{"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-105","SUBJID":"id-105","SITEID":"BRA-1","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.15691,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-08 05:39:28","TRTEDTM":"2022-02-14 20:58:26","TRT01SDTM":"2020-03-08 05:39:28","TRT01EDTM":"2021-02-14 14:58:26","TRT02SDTM":"2021-02-14 14:58:26","TRT02EDTM":"2022-02-14 20:58:26","AP01SDTM":"2020-03-08 05:39:28","AP01EDTM":"2021-02-14 14:58:26","AP02SDTM":"2021-02-14 14:58:26","AP02EDTM":"2022-02-14 20:58:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":709,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6364,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.29792,"AVALU":"U/L","BASE2":4.29792,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-05-27 05:39:28","ADY":80,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-105","SUBJID":"id-105","SITEID":"BRA-1","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.15691,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-08 05:39:28","TRTEDTM":"2022-02-14 20:58:26","TRT01SDTM":"2020-03-08 05:39:28","TRT01EDTM":"2021-02-14 14:58:26","TRT02SDTM":"2021-02-14 14:58:26","TRT02EDTM":"2022-02-14 20:58:26","AP01SDTM":"2020-03-08 05:39:28","AP01EDTM":"2021-02-14 14:58:26","AP02SDTM":"2021-02-14 14:58:26","AP02EDTM":"2022-02-14 20:58:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":709,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1658,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.69588,"AVALU":"U/L","BASE2":4.29792,"BASE":24.69588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":20.39796,"PCHG2":474.60062,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-04 05:39:28","ADY":149,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-105","SUBJID":"id-105","SITEID":"BRA-1","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.15691,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-08 05:39:28","TRTEDTM":"2022-02-14 20:58:26","TRT01SDTM":"2020-03-08 05:39:28","TRT01EDTM":"2021-02-14 14:58:26","TRT02SDTM":"2021-02-14 14:58:26","TRT02EDTM":"2022-02-14 20:58:26","AP01SDTM":"2020-03-08 05:39:28","AP01EDTM":"2021-02-14 14:58:26","AP02SDTM":"2021-02-14 14:58:26","AP02EDTM":"2022-02-14 20:58:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":709,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7407,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.87225,"AVALU":"U/L","BASE2":4.29792,"BASE":24.69588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":20.57433,"PCHG2":478.7043,"CHG":0.17637,"PCHG":0.71418,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-16 05:39:28","ADY":314,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-105","SUBJID":"id-105","SITEID":"BRA-1","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.15691,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-08 05:39:28","TRTEDTM":"2022-02-14 20:58:26","TRT01SDTM":"2020-03-08 05:39:28","TRT01EDTM":"2021-02-14 14:58:26","TRT02SDTM":"2021-02-14 14:58:26","TRT02EDTM":"2022-02-14 20:58:26","AP01SDTM":"2020-03-08 05:39:28","AP01EDTM":"2021-02-14 14:58:26","AP02SDTM":"2021-02-14 14:58:26","AP02EDTM":"2022-02-14 20:58:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":709,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7315,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.66681,"AVALU":"U/L","BASE2":4.29792,"BASE":24.69588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.63111,"PCHG2":-14.68412,"CHG":-21.02907,"PCHG":-85.15214,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-04-10 05:39:28","ADY":398,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-105","SUBJID":"id-105","SITEID":"BRA-1","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.15691,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-08 05:39:28","TRTEDTM":"2022-02-14 20:58:26","TRT01SDTM":"2020-03-08 05:39:28","TRT01EDTM":"2021-02-14 14:58:26","TRT02SDTM":"2021-02-14 14:58:26","TRT02EDTM":"2022-02-14 20:58:26","AP01SDTM":"2020-03-08 05:39:28","AP01EDTM":"2021-02-14 14:58:26","AP02SDTM":"2021-02-14 14:58:26","AP02EDTM":"2022-02-14 20:58:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":709,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1986,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.54845,"AVALU":"U/L","BASE2":4.29792,"BASE":24.69588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.25053,"PCHG2":331.56792,"CHG":-6.14743,"PCHG":-24.89254,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-21 05:39:28","ADY":470,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-105","SUBJID":"id-105","SITEID":"BRA-1","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.15691,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-08 05:39:28","TRTEDTM":"2022-02-14 20:58:26","TRT01SDTM":"2020-03-08 05:39:28","TRT01EDTM":"2021-02-14 14:58:26","TRT02SDTM":"2021-02-14 14:58:26","TRT02EDTM":"2022-02-14 20:58:26","AP01SDTM":"2020-03-08 05:39:28","AP01EDTM":"2021-02-14 14:58:26","AP02SDTM":"2021-02-14 14:58:26","AP02EDTM":"2022-02-14 20:58:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":709,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6455,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.72746,"AVALU":"U/L","BASE2":4.29792,"BASE":24.69588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.42954,"PCHG2":79.79526,"CHG":-16.96842,"PCHG":-68.70953,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-18 05:39:28","ADY":528,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-105","SUBJID":"id-105","SITEID":"BRA-1","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.15691,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-08 05:39:28","TRTEDTM":"2022-02-14 20:58:26","TRT01SDTM":"2020-03-08 05:39:28","TRT01EDTM":"2021-02-14 14:58:26","TRT02SDTM":"2021-02-14 14:58:26","TRT02EDTM":"2022-02-14 20:58:26","AP01SDTM":"2020-03-08 05:39:28","AP01EDTM":"2021-02-14 14:58:26","AP02SDTM":"2021-02-14 14:58:26","AP02EDTM":"2022-02-14 20:58:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":709,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1870,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.51008,"AVALU":"U/L","BASE2":4.29792,"BASE":24.69588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.21216,"PCHG2":447.01059,"CHG":-1.1858,"PCHG":-4.8016,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-25 05:39:28","ADY":535,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-105","SUBJID":"id-105","SITEID":"BRA-1","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.15691,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-08 05:39:28","TRTEDTM":"2022-02-14 20:58:26","TRT01SDTM":"2020-03-08 05:39:28","TRT01EDTM":"2021-02-14 14:58:26","TRT02SDTM":"2021-02-14 14:58:26","TRT02EDTM":"2022-02-14 20:58:26","AP01SDTM":"2020-03-08 05:39:28","AP01EDTM":"2021-02-14 14:58:26","AP02SDTM":"2021-02-14 14:58:26","AP02EDTM":"2022-02-14 20:58:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":709,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6367,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.08534,"AVALU":"mg/L","BASE2":9.08534,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-27 05:39:28","ADY":80,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-105","SUBJID":"id-105","SITEID":"BRA-1","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.15691,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-08 05:39:28","TRTEDTM":"2022-02-14 20:58:26","TRT01SDTM":"2020-03-08 05:39:28","TRT01EDTM":"2021-02-14 14:58:26","TRT02SDTM":"2021-02-14 14:58:26","TRT02EDTM":"2022-02-14 20:58:26","AP01SDTM":"2020-03-08 05:39:28","AP01EDTM":"2021-02-14 14:58:26","AP02SDTM":"2021-02-14 14:58:26","AP02EDTM":"2022-02-14 20:58:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":709,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4770,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.15368,"AVALU":"mg/L","BASE2":9.08534,"BASE":9.15368,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.06834,"PCHG2":0.75217,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-04 05:39:28","ADY":149,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-105","SUBJID":"id-105","SITEID":"BRA-1","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.15691,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-08 05:39:28","TRTEDTM":"2022-02-14 20:58:26","TRT01SDTM":"2020-03-08 05:39:28","TRT01EDTM":"2021-02-14 14:58:26","TRT02SDTM":"2021-02-14 14:58:26","TRT02EDTM":"2022-02-14 20:58:26","AP01SDTM":"2020-03-08 05:39:28","AP01EDTM":"2021-02-14 14:58:26","AP02SDTM":"2021-02-14 14:58:26","AP02EDTM":"2022-02-14 20:58:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":709,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1161,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.89204,"AVALU":"mg/L","BASE2":9.08534,"BASE":9.15368,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.8067,"PCHG2":19.88587,"CHG":1.73836,"PCHG":18.99085,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-01-16 05:39:28","ADY":314,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-105","SUBJID":"id-105","SITEID":"BRA-1","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.15691,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-08 05:39:28","TRTEDTM":"2022-02-14 20:58:26","TRT01SDTM":"2020-03-08 05:39:28","TRT01EDTM":"2021-02-14 14:58:26","TRT02SDTM":"2021-02-14 14:58:26","TRT02EDTM":"2022-02-14 20:58:26","AP01SDTM":"2020-03-08 05:39:28","AP01EDTM":"2021-02-14 14:58:26","AP02SDTM":"2021-02-14 14:58:26","AP02EDTM":"2022-02-14 20:58:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":709,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":900,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.14172,"AVALU":"mg/L","BASE2":9.08534,"BASE":9.15368,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.94362,"PCHG2":-10.38617,"CHG":-1.01196,"PCHG":-11.05518,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-10 05:39:28","ADY":398,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-105","SUBJID":"id-105","SITEID":"BRA-1","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.15691,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-08 05:39:28","TRTEDTM":"2022-02-14 20:58:26","TRT01SDTM":"2020-03-08 05:39:28","TRT01EDTM":"2021-02-14 14:58:26","TRT02SDTM":"2021-02-14 14:58:26","TRT02EDTM":"2022-02-14 20:58:26","AP01SDTM":"2020-03-08 05:39:28","AP01EDTM":"2021-02-14 14:58:26","AP02SDTM":"2021-02-14 14:58:26","AP02EDTM":"2022-02-14 20:58:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":709,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5671,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.59205,"AVALU":"mg/L","BASE2":9.08534,"BASE":9.15368,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.50671,"PCHG2":16.58397,"CHG":1.43837,"PCHG":15.71361,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-06-21 05:39:28","ADY":470,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-105","SUBJID":"id-105","SITEID":"BRA-1","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.15691,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-08 05:39:28","TRTEDTM":"2022-02-14 20:58:26","TRT01SDTM":"2020-03-08 05:39:28","TRT01EDTM":"2021-02-14 14:58:26","TRT02SDTM":"2021-02-14 14:58:26","TRT02EDTM":"2022-02-14 20:58:26","AP01SDTM":"2020-03-08 05:39:28","AP01EDTM":"2021-02-14 14:58:26","AP02SDTM":"2021-02-14 14:58:26","AP02EDTM":"2022-02-14 20:58:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":709,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":129,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.08754,"AVALU":"mg/L","BASE2":9.08534,"BASE":9.15368,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.0022,"PCHG2":11.03091,"CHG":0.93386,"PCHG":10.202,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-08-18 05:39:28","ADY":528,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-105","SUBJID":"id-105","SITEID":"BRA-1","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.15691,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-08 05:39:28","TRTEDTM":"2022-02-14 20:58:26","TRT01SDTM":"2020-03-08 05:39:28","TRT01EDTM":"2021-02-14 14:58:26","TRT02SDTM":"2021-02-14 14:58:26","TRT02EDTM":"2022-02-14 20:58:26","AP01SDTM":"2020-03-08 05:39:28","AP01EDTM":"2021-02-14 14:58:26","AP02SDTM":"2021-02-14 14:58:26","AP02EDTM":"2022-02-14 20:58:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":709,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2287,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.20441,"AVALU":"mg/L","BASE2":9.08534,"BASE":9.15368,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11907,"PCHG2":1.31055,"CHG":0.05073,"PCHG":0.55421,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-25 05:39:28","ADY":535,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-105","SUBJID":"id-105","SITEID":"BRA-1","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.15691,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-08 05:39:28","TRTEDTM":"2022-02-14 20:58:26","TRT01SDTM":"2020-03-08 05:39:28","TRT01EDTM":"2021-02-14 14:58:26","TRT02SDTM":"2021-02-14 14:58:26","TRT02EDTM":"2022-02-14 20:58:26","AP01SDTM":"2020-03-08 05:39:28","AP01EDTM":"2021-02-14 14:58:26","AP02SDTM":"2021-02-14 14:58:26","AP02EDTM":"2022-02-14 20:58:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":709,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1025,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84139,"AVALU":"g/L","BASE2":2.84139,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-27 05:39:28","ADY":80,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-105","SUBJID":"id-105","SITEID":"BRA-1","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.15691,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-08 05:39:28","TRTEDTM":"2022-02-14 20:58:26","TRT01SDTM":"2020-03-08 05:39:28","TRT01EDTM":"2021-02-14 14:58:26","TRT02SDTM":"2021-02-14 14:58:26","TRT02EDTM":"2022-02-14 20:58:26","AP01SDTM":"2020-03-08 05:39:28","AP01EDTM":"2021-02-14 14:58:26","AP02SDTM":"2021-02-14 14:58:26","AP02EDTM":"2022-02-14 20:58:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":709,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4290,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9273,"AVALU":"g/L","BASE2":2.84139,"BASE":2.9273,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.08592,"PCHG2":3.02379,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-04 05:39:28","ADY":149,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-105","SUBJID":"id-105","SITEID":"BRA-1","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.15691,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-08 05:39:28","TRTEDTM":"2022-02-14 20:58:26","TRT01SDTM":"2020-03-08 05:39:28","TRT01EDTM":"2021-02-14 14:58:26","TRT02SDTM":"2021-02-14 14:58:26","TRT02EDTM":"2022-02-14 20:58:26","AP01SDTM":"2020-03-08 05:39:28","AP01EDTM":"2021-02-14 14:58:26","AP02SDTM":"2021-02-14 14:58:26","AP02EDTM":"2022-02-14 20:58:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":709,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5534,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.65926,"AVALU":"g/L","BASE2":2.84139,"BASE":2.9273,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18212,"PCHG2":-6.40961,"CHG":-0.26804,"PCHG":-9.15653,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-16 05:39:28","ADY":314,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-105","SUBJID":"id-105","SITEID":"BRA-1","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.15691,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-08 05:39:28","TRTEDTM":"2022-02-14 20:58:26","TRT01SDTM":"2020-03-08 05:39:28","TRT01EDTM":"2021-02-14 14:58:26","TRT02SDTM":"2021-02-14 14:58:26","TRT02EDTM":"2022-02-14 20:58:26","AP01SDTM":"2020-03-08 05:39:28","AP01EDTM":"2021-02-14 14:58:26","AP02SDTM":"2021-02-14 14:58:26","AP02EDTM":"2022-02-14 20:58:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":709,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2779,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86203,"AVALU":"g/L","BASE2":2.84139,"BASE":2.9273,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02064,"PCHG2":0.7265,"CHG":-0.06527,"PCHG":-2.22986,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-10 05:39:28","ADY":398,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-105","SUBJID":"id-105","SITEID":"BRA-1","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.15691,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-08 05:39:28","TRTEDTM":"2022-02-14 20:58:26","TRT01SDTM":"2020-03-08 05:39:28","TRT01EDTM":"2021-02-14 14:58:26","TRT02SDTM":"2021-02-14 14:58:26","TRT02EDTM":"2022-02-14 20:58:26","AP01SDTM":"2020-03-08 05:39:28","AP01EDTM":"2021-02-14 14:58:26","AP02SDTM":"2021-02-14 14:58:26","AP02EDTM":"2022-02-14 20:58:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":709,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3009,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88083,"AVALU":"g/L","BASE2":2.84139,"BASE":2.9273,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03944,"PCHG2":1.38812,"CHG":-0.04648,"PCHG":-1.58767,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-21 05:39:28","ADY":470,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-105","SUBJID":"id-105","SITEID":"BRA-1","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.15691,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-08 05:39:28","TRTEDTM":"2022-02-14 20:58:26","TRT01SDTM":"2020-03-08 05:39:28","TRT01EDTM":"2021-02-14 14:58:26","TRT02SDTM":"2021-02-14 14:58:26","TRT02EDTM":"2022-02-14 20:58:26","AP01SDTM":"2020-03-08 05:39:28","AP01EDTM":"2021-02-14 14:58:26","AP02SDTM":"2021-02-14 14:58:26","AP02EDTM":"2022-02-14 20:58:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":709,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4107,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92782,"AVALU":"g/L","BASE2":2.84139,"BASE":2.9273,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08643,"PCHG2":3.04197,"CHG":0.00052,"PCHG":0.01765,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-18 05:39:28","ADY":528,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-105","SUBJID":"id-105","SITEID":"BRA-1","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.15691,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-08 05:39:28","TRTEDTM":"2022-02-14 20:58:26","TRT01SDTM":"2020-03-08 05:39:28","TRT01EDTM":"2021-02-14 14:58:26","TRT02SDTM":"2021-02-14 14:58:26","TRT02EDTM":"2022-02-14 20:58:26","AP01SDTM":"2020-03-08 05:39:28","AP01EDTM":"2021-02-14 14:58:26","AP02SDTM":"2021-02-14 14:58:26","AP02EDTM":"2022-02-14 20:58:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":709,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1984,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88469,"AVALU":"g/L","BASE2":2.84139,"BASE":2.9273,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0433,"PCHG2":1.52404,"CHG":-0.04261,"PCHG":-1.45573,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-25 05:39:28","ADY":535,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-134","SUBJID":"id-134","SITEID":"BRA-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":6.46299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-03","TRTSDTM":"2020-11-04 04:08:58","TRTEDTM":"2022-02-20 03:33:55","TRT01SDTM":"2020-11-04 04:08:58","TRT01EDTM":"2021-02-19 21:33:55","TRT02SDTM":"2021-02-19 21:33:55","TRT02EDTM":"2022-02-20 03:33:55","AP01SDTM":"2020-11-04 04:08:58","AP01EDTM":"2021-02-19 21:33:55","AP02SDTM":"2021-02-19 21:33:55","AP02EDTM":"2022-02-20 03:33:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":473,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":24,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":496,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4641,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.36543,"AVALU":"U/L","BASE2":7.36543,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-17 04:08:58","ADY":225,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-134","SUBJID":"id-134","SITEID":"BRA-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":6.46299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-03","TRTSDTM":"2020-11-04 04:08:58","TRTEDTM":"2022-02-20 03:33:55","TRT01SDTM":"2020-11-04 04:08:58","TRT01EDTM":"2021-02-19 21:33:55","TRT02SDTM":"2021-02-19 21:33:55","TRT02EDTM":"2022-02-20 03:33:55","AP01SDTM":"2020-11-04 04:08:58","AP01EDTM":"2021-02-19 21:33:55","AP02SDTM":"2021-02-19 21:33:55","AP02EDTM":"2022-02-20 03:33:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":473,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":24,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":496,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2388,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.417,"AVALU":"U/L","BASE2":7.36543,"BASE":16.417,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":9.05158,"PCHG2":122.8928,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-19 04:08:58","ADY":227,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-134","SUBJID":"id-134","SITEID":"BRA-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":6.46299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-03","TRTSDTM":"2020-11-04 04:08:58","TRTEDTM":"2022-02-20 03:33:55","TRT01SDTM":"2020-11-04 04:08:58","TRT01EDTM":"2021-02-19 21:33:55","TRT02SDTM":"2021-02-19 21:33:55","TRT02EDTM":"2022-02-20 03:33:55","AP01SDTM":"2020-11-04 04:08:58","AP01EDTM":"2021-02-19 21:33:55","AP02SDTM":"2021-02-19 21:33:55","AP02EDTM":"2022-02-20 03:33:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":473,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":24,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":496,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2823,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.16203,"AVALU":"U/L","BASE2":7.36543,"BASE":16.417,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.7966,"PCHG2":51.54626,"CHG":-5.25498,"PCHG":-32.00935,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-17 04:08:58","ADY":255,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-134","SUBJID":"id-134","SITEID":"BRA-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":6.46299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-03","TRTSDTM":"2020-11-04 04:08:58","TRTEDTM":"2022-02-20 03:33:55","TRT01SDTM":"2020-11-04 04:08:58","TRT01EDTM":"2021-02-19 21:33:55","TRT02SDTM":"2021-02-19 21:33:55","TRT02EDTM":"2022-02-20 03:33:55","AP01SDTM":"2020-11-04 04:08:58","AP01EDTM":"2021-02-19 21:33:55","AP02SDTM":"2021-02-19 21:33:55","AP02EDTM":"2022-02-20 03:33:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":473,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":24,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":496,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6731,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.88959,"AVALU":"U/L","BASE2":7.36543,"BASE":16.417,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.52416,"PCHG2":115.73209,"CHG":-0.52742,"PCHG":-3.21263,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-31 04:08:58","ADY":269,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-134","SUBJID":"id-134","SITEID":"BRA-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":6.46299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-03","TRTSDTM":"2020-11-04 04:08:58","TRTEDTM":"2022-02-20 03:33:55","TRT01SDTM":"2020-11-04 04:08:58","TRT01EDTM":"2021-02-19 21:33:55","TRT02SDTM":"2021-02-19 21:33:55","TRT02EDTM":"2022-02-20 03:33:55","AP01SDTM":"2020-11-04 04:08:58","AP01EDTM":"2021-02-19 21:33:55","AP02SDTM":"2021-02-19 21:33:55","AP02EDTM":"2022-02-20 03:33:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":473,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":24,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":496,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5941,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.35408,"AVALU":"U/L","BASE2":7.36543,"BASE":16.417,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.98866,"PCHG2":230.65409,"CHG":7.93708,"PCHG":48.34669,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-27 04:08:58","ADY":357,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-134","SUBJID":"id-134","SITEID":"BRA-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":6.46299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-03","TRTSDTM":"2020-11-04 04:08:58","TRTEDTM":"2022-02-20 03:33:55","TRT01SDTM":"2020-11-04 04:08:58","TRT01EDTM":"2021-02-19 21:33:55","TRT02SDTM":"2021-02-19 21:33:55","TRT02EDTM":"2022-02-20 03:33:55","AP01SDTM":"2020-11-04 04:08:58","AP01EDTM":"2021-02-19 21:33:55","AP02SDTM":"2021-02-19 21:33:55","AP02EDTM":"2022-02-20 03:33:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":473,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":24,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":496,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2168,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.02648,"AVALU":"U/L","BASE2":7.36543,"BASE":16.417,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.66106,"PCHG2":117.5907,"CHG":-0.39052,"PCHG":-2.37877,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-14 04:08:58","ADY":436,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-134","SUBJID":"id-134","SITEID":"BRA-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":6.46299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-03","TRTSDTM":"2020-11-04 04:08:58","TRTEDTM":"2022-02-20 03:33:55","TRT01SDTM":"2020-11-04 04:08:58","TRT01EDTM":"2021-02-19 21:33:55","TRT02SDTM":"2021-02-19 21:33:55","TRT02EDTM":"2022-02-20 03:33:55","AP01SDTM":"2020-11-04 04:08:58","AP01EDTM":"2021-02-19 21:33:55","AP02SDTM":"2021-02-19 21:33:55","AP02EDTM":"2022-02-20 03:33:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":473,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":24,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":496,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5517,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.20915,"AVALU":"U/L","BASE2":7.36543,"BASE":16.417,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.84372,"PCHG2":133.64767,"CHG":0.79214,"PCHG":4.82513,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-18 04:08:58","ADY":440,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-134","SUBJID":"id-134","SITEID":"BRA-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":6.46299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-03","TRTSDTM":"2020-11-04 04:08:58","TRTEDTM":"2022-02-20 03:33:55","TRT01SDTM":"2020-11-04 04:08:58","TRT01EDTM":"2021-02-19 21:33:55","TRT02SDTM":"2021-02-19 21:33:55","TRT02EDTM":"2022-02-20 03:33:55","AP01SDTM":"2020-11-04 04:08:58","AP01EDTM":"2021-02-19 21:33:55","AP02SDTM":"2021-02-19 21:33:55","AP02EDTM":"2022-02-20 03:33:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":473,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":24,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":496,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1446,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.46051,"AVALU":"mg/L","BASE2":10.46051,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"","ATOXGR":"1","BTOXGR":"-1","ADTM":"2021-06-17 04:08:58","ADY":225,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-134","SUBJID":"id-134","SITEID":"BRA-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":6.46299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-03","TRTSDTM":"2020-11-04 04:08:58","TRTEDTM":"2022-02-20 03:33:55","TRT01SDTM":"2020-11-04 04:08:58","TRT01EDTM":"2021-02-19 21:33:55","TRT02SDTM":"2021-02-19 21:33:55","TRT02EDTM":"2022-02-20 03:33:55","AP01SDTM":"2020-11-04 04:08:58","AP01EDTM":"2021-02-19 21:33:55","AP02SDTM":"2021-02-19 21:33:55","AP02EDTM":"2022-02-20 03:33:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":473,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":24,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":496,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8343,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.43498,"AVALU":"mg/L","BASE2":10.46051,"BASE":7.43498,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-3.02554,"PCHG2":-28.9234,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2021-06-19 04:08:58","ADY":227,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-134","SUBJID":"id-134","SITEID":"BRA-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":6.46299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-03","TRTSDTM":"2020-11-04 04:08:58","TRTEDTM":"2022-02-20 03:33:55","TRT01SDTM":"2020-11-04 04:08:58","TRT01EDTM":"2021-02-19 21:33:55","TRT02SDTM":"2021-02-19 21:33:55","TRT02EDTM":"2022-02-20 03:33:55","AP01SDTM":"2020-11-04 04:08:58","AP01EDTM":"2021-02-19 21:33:55","AP02SDTM":"2021-02-19 21:33:55","AP02EDTM":"2022-02-20 03:33:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":473,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":24,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":496,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1000,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.41438,"AVALU":"mg/L","BASE2":10.46051,"BASE":7.43498,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.04613,"PCHG2":-10.00077,"CHG":1.9794,"PCHG":26.62287,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-07-17 04:08:58","ADY":255,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-134","SUBJID":"id-134","SITEID":"BRA-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":6.46299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-03","TRTSDTM":"2020-11-04 04:08:58","TRTEDTM":"2022-02-20 03:33:55","TRT01SDTM":"2020-11-04 04:08:58","TRT01EDTM":"2021-02-19 21:33:55","TRT02SDTM":"2021-02-19 21:33:55","TRT02EDTM":"2022-02-20 03:33:55","AP01SDTM":"2020-11-04 04:08:58","AP01EDTM":"2021-02-19 21:33:55","AP02SDTM":"2021-02-19 21:33:55","AP02EDTM":"2022-02-20 03:33:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":473,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":24,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":496,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6127,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.02258,"AVALU":"mg/L","BASE2":10.46051,"BASE":7.43498,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.43793,"PCHG2":-4.18653,"CHG":2.5876,"PCHG":34.80311,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"4","BTOXGR":"-1","ADTM":"2021-07-31 04:08:58","ADY":269,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-134","SUBJID":"id-134","SITEID":"BRA-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":6.46299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-03","TRTSDTM":"2020-11-04 04:08:58","TRTEDTM":"2022-02-20 03:33:55","TRT01SDTM":"2020-11-04 04:08:58","TRT01EDTM":"2021-02-19 21:33:55","TRT02SDTM":"2021-02-19 21:33:55","TRT02EDTM":"2022-02-20 03:33:55","AP01SDTM":"2020-11-04 04:08:58","AP01EDTM":"2021-02-19 21:33:55","AP02SDTM":"2021-02-19 21:33:55","AP02EDTM":"2022-02-20 03:33:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":473,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":24,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":496,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2293,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.01019,"AVALU":"mg/L","BASE2":10.46051,"BASE":7.43498,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.45032,"PCHG2":-23.42444,"CHG":0.57522,"PCHG":7.73666,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-10-27 04:08:58","ADY":357,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-134","SUBJID":"id-134","SITEID":"BRA-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":6.46299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-03","TRTSDTM":"2020-11-04 04:08:58","TRTEDTM":"2022-02-20 03:33:55","TRT01SDTM":"2020-11-04 04:08:58","TRT01EDTM":"2021-02-19 21:33:55","TRT02SDTM":"2021-02-19 21:33:55","TRT02EDTM":"2022-02-20 03:33:55","AP01SDTM":"2020-11-04 04:08:58","AP01EDTM":"2021-02-19 21:33:55","AP02SDTM":"2021-02-19 21:33:55","AP02EDTM":"2022-02-20 03:33:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":473,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":24,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":496,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4190,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.50619,"AVALU":"mg/L","BASE2":10.46051,"BASE":7.43498,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.95432,"PCHG2":-18.68284,"CHG":1.07122,"PCHG":14.40778,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-01-14 04:08:58","ADY":436,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-134","SUBJID":"id-134","SITEID":"BRA-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":6.46299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-03","TRTSDTM":"2020-11-04 04:08:58","TRTEDTM":"2022-02-20 03:33:55","TRT01SDTM":"2020-11-04 04:08:58","TRT01EDTM":"2021-02-19 21:33:55","TRT02SDTM":"2021-02-19 21:33:55","TRT02EDTM":"2022-02-20 03:33:55","AP01SDTM":"2020-11-04 04:08:58","AP01EDTM":"2021-02-19 21:33:55","AP02SDTM":"2021-02-19 21:33:55","AP02EDTM":"2022-02-20 03:33:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":473,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":24,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":496,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4160,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.62993,"AVALU":"mg/L","BASE2":10.46051,"BASE":7.43498,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.83058,"PCHG2":-27.05969,"CHG":0.19495,"PCHG":2.62212,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-3","BTOXGR":"-1","ADTM":"2022-01-18 04:08:58","ADY":440,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-134","SUBJID":"id-134","SITEID":"BRA-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":6.46299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-03","TRTSDTM":"2020-11-04 04:08:58","TRTEDTM":"2022-02-20 03:33:55","TRT01SDTM":"2020-11-04 04:08:58","TRT01EDTM":"2021-02-19 21:33:55","TRT02SDTM":"2021-02-19 21:33:55","TRT02EDTM":"2022-02-20 03:33:55","AP01SDTM":"2020-11-04 04:08:58","AP01EDTM":"2021-02-19 21:33:55","AP02SDTM":"2021-02-19 21:33:55","AP02EDTM":"2022-02-20 03:33:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":473,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":24,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":496,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7526,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85618,"AVALU":"g/L","BASE2":2.85618,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-17 04:08:58","ADY":225,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-134","SUBJID":"id-134","SITEID":"BRA-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":6.46299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-03","TRTSDTM":"2020-11-04 04:08:58","TRTEDTM":"2022-02-20 03:33:55","TRT01SDTM":"2020-11-04 04:08:58","TRT01EDTM":"2021-02-19 21:33:55","TRT02SDTM":"2021-02-19 21:33:55","TRT02EDTM":"2022-02-20 03:33:55","AP01SDTM":"2020-11-04 04:08:58","AP01EDTM":"2021-02-19 21:33:55","AP02SDTM":"2021-02-19 21:33:55","AP02EDTM":"2022-02-20 03:33:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":473,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":24,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":496,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2906,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76211,"AVALU":"g/L","BASE2":2.85618,"BASE":2.76211,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.09407,"PCHG2":-3.29362,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-19 04:08:58","ADY":227,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-134","SUBJID":"id-134","SITEID":"BRA-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":6.46299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-03","TRTSDTM":"2020-11-04 04:08:58","TRTEDTM":"2022-02-20 03:33:55","TRT01SDTM":"2020-11-04 04:08:58","TRT01EDTM":"2021-02-19 21:33:55","TRT02SDTM":"2021-02-19 21:33:55","TRT02EDTM":"2022-02-20 03:33:55","AP01SDTM":"2020-11-04 04:08:58","AP01EDTM":"2021-02-19 21:33:55","AP02SDTM":"2021-02-19 21:33:55","AP02EDTM":"2022-02-20 03:33:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":473,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":24,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":496,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3343,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74585,"AVALU":"g/L","BASE2":2.85618,"BASE":2.76211,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11033,"PCHG2":-3.86299,"CHG":-0.01626,"PCHG":-0.58876,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-17 04:08:58","ADY":255,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-134","SUBJID":"id-134","SITEID":"BRA-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":6.46299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-03","TRTSDTM":"2020-11-04 04:08:58","TRTEDTM":"2022-02-20 03:33:55","TRT01SDTM":"2020-11-04 04:08:58","TRT01EDTM":"2021-02-19 21:33:55","TRT02SDTM":"2021-02-19 21:33:55","TRT02EDTM":"2022-02-20 03:33:55","AP01SDTM":"2020-11-04 04:08:58","AP01EDTM":"2021-02-19 21:33:55","AP02SDTM":"2021-02-19 21:33:55","AP02EDTM":"2022-02-20 03:33:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":473,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":24,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":496,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":505,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84342,"AVALU":"g/L","BASE2":2.85618,"BASE":2.76211,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01277,"PCHG2":-0.44695,"CHG":0.08131,"PCHG":2.94363,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-31 04:08:58","ADY":269,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-134","SUBJID":"id-134","SITEID":"BRA-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":6.46299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-03","TRTSDTM":"2020-11-04 04:08:58","TRTEDTM":"2022-02-20 03:33:55","TRT01SDTM":"2020-11-04 04:08:58","TRT01EDTM":"2021-02-19 21:33:55","TRT02SDTM":"2021-02-19 21:33:55","TRT02EDTM":"2022-02-20 03:33:55","AP01SDTM":"2020-11-04 04:08:58","AP01EDTM":"2021-02-19 21:33:55","AP02SDTM":"2021-02-19 21:33:55","AP02EDTM":"2022-02-20 03:33:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":473,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":24,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":496,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8033,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86363,"AVALU":"g/L","BASE2":2.85618,"BASE":2.76211,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00744,"PCHG2":0.26066,"CHG":0.10152,"PCHG":3.67533,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-27 04:08:58","ADY":357,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-134","SUBJID":"id-134","SITEID":"BRA-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":6.46299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-03","TRTSDTM":"2020-11-04 04:08:58","TRTEDTM":"2022-02-20 03:33:55","TRT01SDTM":"2020-11-04 04:08:58","TRT01EDTM":"2021-02-19 21:33:55","TRT02SDTM":"2021-02-19 21:33:55","TRT02EDTM":"2022-02-20 03:33:55","AP01SDTM":"2020-11-04 04:08:58","AP01EDTM":"2021-02-19 21:33:55","AP02SDTM":"2021-02-19 21:33:55","AP02EDTM":"2022-02-20 03:33:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":473,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":24,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":496,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":404,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98432,"AVALU":"g/L","BASE2":2.85618,"BASE":2.76211,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12814,"PCHG2":4.48642,"CHG":0.22221,"PCHG":8.04501,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-14 04:08:58","ADY":436,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-134","SUBJID":"id-134","SITEID":"BRA-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":6.46299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-03","TRTSDTM":"2020-11-04 04:08:58","TRTEDTM":"2022-02-20 03:33:55","TRT01SDTM":"2020-11-04 04:08:58","TRT01EDTM":"2021-02-19 21:33:55","TRT02SDTM":"2021-02-19 21:33:55","TRT02EDTM":"2022-02-20 03:33:55","AP01SDTM":"2020-11-04 04:08:58","AP01EDTM":"2021-02-19 21:33:55","AP02SDTM":"2021-02-19 21:33:55","AP02EDTM":"2022-02-20 03:33:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":473,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":24,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":496,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6806,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78496,"AVALU":"g/L","BASE2":2.85618,"BASE":2.76211,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07122,"PCHG2":-2.49363,"CHG":0.02285,"PCHG":0.82724,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-18 04:08:58","ADY":440,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-141","SUBJID":"id-141","SITEID":"BRA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.51608,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-22","TRTSDTM":"2020-07-25 14:26:21","TRTEDTM":"2023-07-26 08:26:21","TRT01SDTM":"2020-07-25 14:26:21","TRT01EDTM":"2022-07-26 02:26:21","TRT02SDTM":"2022-07-26 02:26:21","TRT02EDTM":"2023-07-26 08:26:21","AP01SDTM":"2020-07-25 14:26:21","AP01EDTM":"2022-07-26 02:26:21","AP02SDTM":"2022-07-26 02:26:21","AP02EDTM":"2023-07-26 08:26:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-26","EOSDY":1096,"LSTALVDT":"2023-08-08","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3395,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.31821,"AVALU":"U/L","BASE2":11.31821,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-29 14:26:21","ADY":4,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-141","SUBJID":"id-141","SITEID":"BRA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.51608,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-22","TRTSDTM":"2020-07-25 14:26:21","TRTEDTM":"2023-07-26 08:26:21","TRT01SDTM":"2020-07-25 14:26:21","TRT01EDTM":"2022-07-26 02:26:21","TRT02SDTM":"2022-07-26 02:26:21","TRT02EDTM":"2023-07-26 08:26:21","AP01SDTM":"2020-07-25 14:26:21","AP01EDTM":"2022-07-26 02:26:21","AP02SDTM":"2022-07-26 02:26:21","AP02EDTM":"2023-07-26 08:26:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-26","EOSDY":1096,"LSTALVDT":"2023-08-08","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3320,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.76648,"AVALU":"U/L","BASE2":11.31821,"BASE":25.76648,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":14.44826,"PCHG2":127.65497,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-15 14:26:21","ADY":52,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-141","SUBJID":"id-141","SITEID":"BRA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.51608,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-22","TRTSDTM":"2020-07-25 14:26:21","TRTEDTM":"2023-07-26 08:26:21","TRT01SDTM":"2020-07-25 14:26:21","TRT01EDTM":"2022-07-26 02:26:21","TRT02SDTM":"2022-07-26 02:26:21","TRT02EDTM":"2023-07-26 08:26:21","AP01SDTM":"2020-07-25 14:26:21","AP01EDTM":"2022-07-26 02:26:21","AP02SDTM":"2022-07-26 02:26:21","AP02EDTM":"2023-07-26 08:26:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-26","EOSDY":1096,"LSTALVDT":"2023-08-08","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5649,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.72926,"AVALU":"U/L","BASE2":11.31821,"BASE":25.76648,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":21.41105,"PCHG2":189.17337,"CHG":6.96278,"PCHG":27.02265,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-30 14:26:21","ADY":189,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-141","SUBJID":"id-141","SITEID":"BRA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.51608,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-22","TRTSDTM":"2020-07-25 14:26:21","TRTEDTM":"2023-07-26 08:26:21","TRT01SDTM":"2020-07-25 14:26:21","TRT01EDTM":"2022-07-26 02:26:21","TRT02SDTM":"2022-07-26 02:26:21","TRT02EDTM":"2023-07-26 08:26:21","AP01SDTM":"2020-07-25 14:26:21","AP01EDTM":"2022-07-26 02:26:21","AP02SDTM":"2022-07-26 02:26:21","AP02EDTM":"2023-07-26 08:26:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-26","EOSDY":1096,"LSTALVDT":"2023-08-08","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1324,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.69196,"AVALU":"U/L","BASE2":11.31821,"BASE":25.76648,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":23.37374,"PCHG2":206.51443,"CHG":8.92548,"PCHG":34.6399,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-13 14:26:21","ADY":262,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-141","SUBJID":"id-141","SITEID":"BRA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.51608,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-22","TRTSDTM":"2020-07-25 14:26:21","TRTEDTM":"2023-07-26 08:26:21","TRT01SDTM":"2020-07-25 14:26:21","TRT01EDTM":"2022-07-26 02:26:21","TRT02SDTM":"2022-07-26 02:26:21","TRT02EDTM":"2023-07-26 08:26:21","AP01SDTM":"2020-07-25 14:26:21","AP01EDTM":"2022-07-26 02:26:21","AP02SDTM":"2022-07-26 02:26:21","AP02EDTM":"2023-07-26 08:26:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-26","EOSDY":1096,"LSTALVDT":"2023-08-08","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1671,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.58115,"AVALU":"U/L","BASE2":11.31821,"BASE":25.76648,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.73707,"PCHG2":-24.18284,"CHG":-17.18533,"PCHG":-66.69646,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-15 14:26:21","ADY":386,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-141","SUBJID":"id-141","SITEID":"BRA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.51608,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-22","TRTSDTM":"2020-07-25 14:26:21","TRTEDTM":"2023-07-26 08:26:21","TRT01SDTM":"2020-07-25 14:26:21","TRT01EDTM":"2022-07-26 02:26:21","TRT02SDTM":"2022-07-26 02:26:21","TRT02EDTM":"2023-07-26 08:26:21","AP01SDTM":"2020-07-25 14:26:21","AP01EDTM":"2022-07-26 02:26:21","AP02SDTM":"2022-07-26 02:26:21","AP02EDTM":"2023-07-26 08:26:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-26","EOSDY":1096,"LSTALVDT":"2023-08-08","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6279,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.5773,"AVALU":"U/L","BASE2":11.31821,"BASE":25.76648,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.25909,"PCHG2":72.97166,"CHG":-6.18917,"PCHG":-24.02026,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-23 14:26:21","ADY":425,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-141","SUBJID":"id-141","SITEID":"BRA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.51608,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-22","TRTSDTM":"2020-07-25 14:26:21","TRTEDTM":"2023-07-26 08:26:21","TRT01SDTM":"2020-07-25 14:26:21","TRT01EDTM":"2022-07-26 02:26:21","TRT02SDTM":"2022-07-26 02:26:21","TRT02EDTM":"2023-07-26 08:26:21","AP01SDTM":"2020-07-25 14:26:21","AP01EDTM":"2022-07-26 02:26:21","AP02SDTM":"2022-07-26 02:26:21","AP02EDTM":"2023-07-26 08:26:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-26","EOSDY":1096,"LSTALVDT":"2023-08-08","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6891,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.27678,"AVALU":"U/L","BASE2":11.31821,"BASE":25.76648,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.95857,"PCHG2":105.65775,"CHG":-2.48969,"PCHG":-9.66252,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-25 14:26:21","ADY":730,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-141","SUBJID":"id-141","SITEID":"BRA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.51608,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-22","TRTSDTM":"2020-07-25 14:26:21","TRTEDTM":"2023-07-26 08:26:21","TRT01SDTM":"2020-07-25 14:26:21","TRT01EDTM":"2022-07-26 02:26:21","TRT02SDTM":"2022-07-26 02:26:21","TRT02EDTM":"2023-07-26 08:26:21","AP01SDTM":"2020-07-25 14:26:21","AP01EDTM":"2022-07-26 02:26:21","AP02SDTM":"2022-07-26 02:26:21","AP02EDTM":"2023-07-26 08:26:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-26","EOSDY":1096,"LSTALVDT":"2023-08-08","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6034,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.2068,"AVALU":"mg/L","BASE2":9.2068,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"2","ADTM":"2020-07-29 14:26:21","ADY":4,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-141","SUBJID":"id-141","SITEID":"BRA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.51608,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-22","TRTSDTM":"2020-07-25 14:26:21","TRTEDTM":"2023-07-26 08:26:21","TRT01SDTM":"2020-07-25 14:26:21","TRT01EDTM":"2022-07-26 02:26:21","TRT02SDTM":"2022-07-26 02:26:21","TRT02EDTM":"2023-07-26 08:26:21","AP01SDTM":"2020-07-25 14:26:21","AP01EDTM":"2022-07-26 02:26:21","AP02SDTM":"2022-07-26 02:26:21","AP02EDTM":"2023-07-26 08:26:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-26","EOSDY":1096,"LSTALVDT":"2023-08-08","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6418,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.00348,"AVALU":"mg/L","BASE2":9.2068,"BASE":10.00348,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.79669,"PCHG2":8.65322,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2020-09-15 14:26:21","ADY":52,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-141","SUBJID":"id-141","SITEID":"BRA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.51608,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-22","TRTSDTM":"2020-07-25 14:26:21","TRTEDTM":"2023-07-26 08:26:21","TRT01SDTM":"2020-07-25 14:26:21","TRT01EDTM":"2022-07-26 02:26:21","TRT02SDTM":"2022-07-26 02:26:21","TRT02EDTM":"2023-07-26 08:26:21","AP01SDTM":"2020-07-25 14:26:21","AP01EDTM":"2022-07-26 02:26:21","AP02SDTM":"2022-07-26 02:26:21","AP02EDTM":"2023-07-26 08:26:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-26","EOSDY":1096,"LSTALVDT":"2023-08-08","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5409,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.08327,"AVALU":"mg/L","BASE2":9.2068,"BASE":10.00348,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12353,"PCHG2":-1.34174,"CHG":-0.92022,"PCHG":-9.19896,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-01-30 14:26:21","ADY":189,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-141","SUBJID":"id-141","SITEID":"BRA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.51608,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-22","TRTSDTM":"2020-07-25 14:26:21","TRTEDTM":"2023-07-26 08:26:21","TRT01SDTM":"2020-07-25 14:26:21","TRT01EDTM":"2022-07-26 02:26:21","TRT02SDTM":"2022-07-26 02:26:21","TRT02EDTM":"2023-07-26 08:26:21","AP01SDTM":"2020-07-25 14:26:21","AP01EDTM":"2022-07-26 02:26:21","AP02SDTM":"2022-07-26 02:26:21","AP02EDTM":"2023-07-26 08:26:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-26","EOSDY":1096,"LSTALVDT":"2023-08-08","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6470,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.80689,"AVALU":"mg/L","BASE2":9.2068,"BASE":10.00348,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.39991,"PCHG2":-4.34369,"CHG":-1.1966,"PCHG":-11.96183,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-04-13 14:26:21","ADY":262,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-141","SUBJID":"id-141","SITEID":"BRA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.51608,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-22","TRTSDTM":"2020-07-25 14:26:21","TRTEDTM":"2023-07-26 08:26:21","TRT01SDTM":"2020-07-25 14:26:21","TRT01EDTM":"2022-07-26 02:26:21","TRT02SDTM":"2022-07-26 02:26:21","TRT02EDTM":"2023-07-26 08:26:21","AP01SDTM":"2020-07-25 14:26:21","AP01EDTM":"2022-07-26 02:26:21","AP02SDTM":"2022-07-26 02:26:21","AP02EDTM":"2023-07-26 08:26:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-26","EOSDY":1096,"LSTALVDT":"2023-08-08","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":387,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.80986,"AVALU":"mg/L","BASE2":9.2068,"BASE":10.00348,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.39694,"PCHG2":-4.31136,"CHG":-1.19362,"PCHG":-11.93208,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-08-15 14:26:21","ADY":386,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-141","SUBJID":"id-141","SITEID":"BRA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.51608,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-22","TRTSDTM":"2020-07-25 14:26:21","TRTEDTM":"2023-07-26 08:26:21","TRT01SDTM":"2020-07-25 14:26:21","TRT01EDTM":"2022-07-26 02:26:21","TRT02SDTM":"2022-07-26 02:26:21","TRT02EDTM":"2023-07-26 08:26:21","AP01SDTM":"2020-07-25 14:26:21","AP01EDTM":"2022-07-26 02:26:21","AP02SDTM":"2022-07-26 02:26:21","AP02EDTM":"2023-07-26 08:26:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-26","EOSDY":1096,"LSTALVDT":"2023-08-08","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1908,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.79494,"AVALU":"mg/L","BASE2":9.2068,"BASE":10.00348,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.41186,"PCHG2":-4.47338,"CHG":-1.20854,"PCHG":-12.08119,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-09-23 14:26:21","ADY":425,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-141","SUBJID":"id-141","SITEID":"BRA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.51608,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-22","TRTSDTM":"2020-07-25 14:26:21","TRTEDTM":"2023-07-26 08:26:21","TRT01SDTM":"2020-07-25 14:26:21","TRT01EDTM":"2022-07-26 02:26:21","TRT02SDTM":"2022-07-26 02:26:21","TRT02EDTM":"2023-07-26 08:26:21","AP01SDTM":"2020-07-25 14:26:21","AP01EDTM":"2022-07-26 02:26:21","AP02SDTM":"2022-07-26 02:26:21","AP02EDTM":"2023-07-26 08:26:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-26","EOSDY":1096,"LSTALVDT":"2023-08-08","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":532,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.92349,"AVALU":"mg/L","BASE2":9.2068,"BASE":10.00348,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.28331,"PCHG2":-3.07714,"CHG":-1.07999,"PCHG":-10.79615,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-07-25 14:26:21","ADY":730,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-141","SUBJID":"id-141","SITEID":"BRA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.51608,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-22","TRTSDTM":"2020-07-25 14:26:21","TRTEDTM":"2023-07-26 08:26:21","TRT01SDTM":"2020-07-25 14:26:21","TRT01EDTM":"2022-07-26 02:26:21","TRT02SDTM":"2022-07-26 02:26:21","TRT02EDTM":"2023-07-26 08:26:21","AP01SDTM":"2020-07-25 14:26:21","AP01EDTM":"2022-07-26 02:26:21","AP02SDTM":"2022-07-26 02:26:21","AP02EDTM":"2023-07-26 08:26:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-26","EOSDY":1096,"LSTALVDT":"2023-08-08","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4669,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83939,"AVALU":"g/L","BASE2":2.83939,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-29 14:26:21","ADY":4,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-141","SUBJID":"id-141","SITEID":"BRA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.51608,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-22","TRTSDTM":"2020-07-25 14:26:21","TRTEDTM":"2023-07-26 08:26:21","TRT01SDTM":"2020-07-25 14:26:21","TRT01EDTM":"2022-07-26 02:26:21","TRT02SDTM":"2022-07-26 02:26:21","TRT02EDTM":"2023-07-26 08:26:21","AP01SDTM":"2020-07-25 14:26:21","AP01EDTM":"2022-07-26 02:26:21","AP02SDTM":"2022-07-26 02:26:21","AP02EDTM":"2023-07-26 08:26:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-26","EOSDY":1096,"LSTALVDT":"2023-08-08","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4025,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.69452,"AVALU":"g/L","BASE2":2.83939,"BASE":2.69452,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.14486,"PCHG2":-5.10187,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-15 14:26:21","ADY":52,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-141","SUBJID":"id-141","SITEID":"BRA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.51608,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-22","TRTSDTM":"2020-07-25 14:26:21","TRTEDTM":"2023-07-26 08:26:21","TRT01SDTM":"2020-07-25 14:26:21","TRT01EDTM":"2022-07-26 02:26:21","TRT02SDTM":"2022-07-26 02:26:21","TRT02EDTM":"2023-07-26 08:26:21","AP01SDTM":"2020-07-25 14:26:21","AP01EDTM":"2022-07-26 02:26:21","AP02SDTM":"2022-07-26 02:26:21","AP02EDTM":"2023-07-26 08:26:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-26","EOSDY":1096,"LSTALVDT":"2023-08-08","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1872,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85191,"AVALU":"g/L","BASE2":2.83939,"BASE":2.69452,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01252,"PCHG2":0.44103,"CHG":0.15738,"PCHG":5.8409,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-30 14:26:21","ADY":189,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-141","SUBJID":"id-141","SITEID":"BRA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.51608,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-22","TRTSDTM":"2020-07-25 14:26:21","TRTEDTM":"2023-07-26 08:26:21","TRT01SDTM":"2020-07-25 14:26:21","TRT01EDTM":"2022-07-26 02:26:21","TRT02SDTM":"2022-07-26 02:26:21","TRT02EDTM":"2023-07-26 08:26:21","AP01SDTM":"2020-07-25 14:26:21","AP01EDTM":"2022-07-26 02:26:21","AP02SDTM":"2022-07-26 02:26:21","AP02EDTM":"2023-07-26 08:26:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-26","EOSDY":1096,"LSTALVDT":"2023-08-08","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1764,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80992,"AVALU":"g/L","BASE2":2.83939,"BASE":2.69452,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02947,"PCHG2":-1.03774,"CHG":0.1154,"PCHG":4.28263,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-13 14:26:21","ADY":262,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-141","SUBJID":"id-141","SITEID":"BRA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.51608,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-22","TRTSDTM":"2020-07-25 14:26:21","TRTEDTM":"2023-07-26 08:26:21","TRT01SDTM":"2020-07-25 14:26:21","TRT01EDTM":"2022-07-26 02:26:21","TRT02SDTM":"2022-07-26 02:26:21","TRT02EDTM":"2023-07-26 08:26:21","AP01SDTM":"2020-07-25 14:26:21","AP01EDTM":"2022-07-26 02:26:21","AP02SDTM":"2022-07-26 02:26:21","AP02EDTM":"2023-07-26 08:26:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-26","EOSDY":1096,"LSTALVDT":"2023-08-08","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6035,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81483,"AVALU":"g/L","BASE2":2.83939,"BASE":2.69452,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02456,"PCHG2":-0.8648,"CHG":0.12031,"PCHG":4.46486,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-15 14:26:21","ADY":386,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-141","SUBJID":"id-141","SITEID":"BRA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.51608,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-22","TRTSDTM":"2020-07-25 14:26:21","TRTEDTM":"2023-07-26 08:26:21","TRT01SDTM":"2020-07-25 14:26:21","TRT01EDTM":"2022-07-26 02:26:21","TRT02SDTM":"2022-07-26 02:26:21","TRT02EDTM":"2023-07-26 08:26:21","AP01SDTM":"2020-07-25 14:26:21","AP01EDTM":"2022-07-26 02:26:21","AP02SDTM":"2022-07-26 02:26:21","AP02EDTM":"2023-07-26 08:26:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-26","EOSDY":1096,"LSTALVDT":"2023-08-08","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":179,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87091,"AVALU":"g/L","BASE2":2.83939,"BASE":2.69452,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03153,"PCHG2":1.11035,"CHG":0.17639,"PCHG":6.5462,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-23 14:26:21","ADY":425,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-141","SUBJID":"id-141","SITEID":"BRA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.51608,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-22","TRTSDTM":"2020-07-25 14:26:21","TRTEDTM":"2023-07-26 08:26:21","TRT01SDTM":"2020-07-25 14:26:21","TRT01EDTM":"2022-07-26 02:26:21","TRT02SDTM":"2022-07-26 02:26:21","TRT02EDTM":"2023-07-26 08:26:21","AP01SDTM":"2020-07-25 14:26:21","AP01EDTM":"2022-07-26 02:26:21","AP02SDTM":"2022-07-26 02:26:21","AP02EDTM":"2023-07-26 08:26:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-26","EOSDY":1096,"LSTALVDT":"2023-08-08","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5678,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01413,"AVALU":"g/L","BASE2":2.83939,"BASE":2.69452,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17474,"PCHG2":6.15432,"CHG":0.31961,"PCHG":11.86134,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-07-25 14:26:21","ADY":730,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-236","SUBJID":"id-236","SITEID":"BRA-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.663,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 08:57:38","TRTEDTM":"2024-01-16 02:57:38","TRT01SDTM":"2021-01-15 08:57:38","TRT01EDTM":"2023-01-15 20:57:38","TRT02SDTM":"2023-01-15 20:57:38","TRT02EDTM":"2024-01-16 02:57:38","AP01SDTM":"2021-01-15 08:57:38","AP01EDTM":"2023-01-15 20:57:38","AP02SDTM":"2023-01-15 20:57:38","AP02EDTM":"2024-01-16 02:57:38","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-16","EOSDY":1096,"LSTALVDT":"2024-01-26","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4592,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.43479,"AVALU":"U/L","BASE2":17.43479,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-27 08:57:38","ADY":12,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-236","SUBJID":"id-236","SITEID":"BRA-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.663,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 08:57:38","TRTEDTM":"2024-01-16 02:57:38","TRT01SDTM":"2021-01-15 08:57:38","TRT01EDTM":"2023-01-15 20:57:38","TRT02SDTM":"2023-01-15 20:57:38","TRT02EDTM":"2024-01-16 02:57:38","AP01SDTM":"2021-01-15 08:57:38","AP01EDTM":"2023-01-15 20:57:38","AP02SDTM":"2023-01-15 20:57:38","AP02EDTM":"2024-01-16 02:57:38","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-16","EOSDY":1096,"LSTALVDT":"2024-01-26","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3401,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.52322,"AVALU":"U/L","BASE2":17.43479,"BASE":29.52322,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":12.08843,"PCHG2":69.33513,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-17 08:57:38","ADY":275,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-236","SUBJID":"id-236","SITEID":"BRA-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.663,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 08:57:38","TRTEDTM":"2024-01-16 02:57:38","TRT01SDTM":"2021-01-15 08:57:38","TRT01EDTM":"2023-01-15 20:57:38","TRT02SDTM":"2023-01-15 20:57:38","TRT02EDTM":"2024-01-16 02:57:38","AP01SDTM":"2021-01-15 08:57:38","AP01EDTM":"2023-01-15 20:57:38","AP02SDTM":"2023-01-15 20:57:38","AP02EDTM":"2024-01-16 02:57:38","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-16","EOSDY":1096,"LSTALVDT":"2024-01-26","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5156,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.28502,"AVALU":"U/L","BASE2":17.43479,"BASE":29.52322,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.85023,"PCHG2":27.81928,"CHG":-7.2382,"PCHG":-24.51698,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-22 08:57:38","ADY":431,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-236","SUBJID":"id-236","SITEID":"BRA-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.663,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 08:57:38","TRTEDTM":"2024-01-16 02:57:38","TRT01SDTM":"2021-01-15 08:57:38","TRT01EDTM":"2023-01-15 20:57:38","TRT02SDTM":"2023-01-15 20:57:38","TRT02EDTM":"2024-01-16 02:57:38","AP01SDTM":"2021-01-15 08:57:38","AP01EDTM":"2023-01-15 20:57:38","AP02SDTM":"2023-01-15 20:57:38","AP02EDTM":"2024-01-16 02:57:38","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-16","EOSDY":1096,"LSTALVDT":"2024-01-26","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3933,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.05523,"AVALU":"U/L","BASE2":17.43479,"BASE":29.52322,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.37956,"PCHG2":-42.32663,"CHG":-19.46799,"PCHG":-65.94129,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-07 08:57:38","ADY":781,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-236","SUBJID":"id-236","SITEID":"BRA-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.663,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 08:57:38","TRTEDTM":"2024-01-16 02:57:38","TRT01SDTM":"2021-01-15 08:57:38","TRT01EDTM":"2023-01-15 20:57:38","TRT02SDTM":"2023-01-15 20:57:38","TRT02EDTM":"2024-01-16 02:57:38","AP01SDTM":"2021-01-15 08:57:38","AP01EDTM":"2023-01-15 20:57:38","AP02SDTM":"2023-01-15 20:57:38","AP02EDTM":"2024-01-16 02:57:38","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-16","EOSDY":1096,"LSTALVDT":"2024-01-26","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3238,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.15557,"AVALU":"U/L","BASE2":17.43479,"BASE":29.52322,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.72079,"PCHG2":61.4908,"CHG":-1.36764,"PCHG":-4.63243,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-20 08:57:38","ADY":794,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-236","SUBJID":"id-236","SITEID":"BRA-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.663,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 08:57:38","TRTEDTM":"2024-01-16 02:57:38","TRT01SDTM":"2021-01-15 08:57:38","TRT01EDTM":"2023-01-15 20:57:38","TRT02SDTM":"2023-01-15 20:57:38","TRT02EDTM":"2024-01-16 02:57:38","AP01SDTM":"2021-01-15 08:57:38","AP01EDTM":"2023-01-15 20:57:38","AP02SDTM":"2023-01-15 20:57:38","AP02EDTM":"2024-01-16 02:57:38","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-16","EOSDY":1096,"LSTALVDT":"2024-01-26","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6581,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.63355,"AVALU":"U/L","BASE2":17.43479,"BASE":29.52322,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.80123,"PCHG2":-79.15917,"CHG":-25.88966,"PCHG":-87.69256,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2023-09-30 08:57:38","ADY":988,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-236","SUBJID":"id-236","SITEID":"BRA-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.663,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 08:57:38","TRTEDTM":"2024-01-16 02:57:38","TRT01SDTM":"2021-01-15 08:57:38","TRT01EDTM":"2023-01-15 20:57:38","TRT02SDTM":"2023-01-15 20:57:38","TRT02EDTM":"2024-01-16 02:57:38","AP01SDTM":"2021-01-15 08:57:38","AP01EDTM":"2023-01-15 20:57:38","AP02SDTM":"2023-01-15 20:57:38","AP02EDTM":"2024-01-16 02:57:38","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-16","EOSDY":1096,"LSTALVDT":"2024-01-26","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7895,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.10223,"AVALU":"U/L","BASE2":17.43479,"BASE":29.52322,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.66744,"PCHG2":21.0352,"CHG":-8.42099,"PCHG":-28.52328,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-11-15 08:57:38","ADY":1034,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-236","SUBJID":"id-236","SITEID":"BRA-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.663,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 08:57:38","TRTEDTM":"2024-01-16 02:57:38","TRT01SDTM":"2021-01-15 08:57:38","TRT01EDTM":"2023-01-15 20:57:38","TRT02SDTM":"2023-01-15 20:57:38","TRT02EDTM":"2024-01-16 02:57:38","AP01SDTM":"2021-01-15 08:57:38","AP01EDTM":"2023-01-15 20:57:38","AP02SDTM":"2023-01-15 20:57:38","AP02EDTM":"2024-01-16 02:57:38","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-16","EOSDY":1096,"LSTALVDT":"2024-01-26","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3069,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.54483,"AVALU":"mg/L","BASE2":10.54483,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-01-27 08:57:38","ADY":12,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-236","SUBJID":"id-236","SITEID":"BRA-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.663,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 08:57:38","TRTEDTM":"2024-01-16 02:57:38","TRT01SDTM":"2021-01-15 08:57:38","TRT01EDTM":"2023-01-15 20:57:38","TRT02SDTM":"2023-01-15 20:57:38","TRT02EDTM":"2024-01-16 02:57:38","AP01SDTM":"2021-01-15 08:57:38","AP01EDTM":"2023-01-15 20:57:38","AP02SDTM":"2023-01-15 20:57:38","AP02EDTM":"2024-01-16 02:57:38","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-16","EOSDY":1096,"LSTALVDT":"2024-01-26","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5334,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.50242,"AVALU":"mg/L","BASE2":10.54483,"BASE":9.50242,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.04241,"PCHG2":-9.88547,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-17 08:57:38","ADY":275,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-236","SUBJID":"id-236","SITEID":"BRA-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.663,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 08:57:38","TRTEDTM":"2024-01-16 02:57:38","TRT01SDTM":"2021-01-15 08:57:38","TRT01EDTM":"2023-01-15 20:57:38","TRT02SDTM":"2023-01-15 20:57:38","TRT02EDTM":"2024-01-16 02:57:38","AP01SDTM":"2021-01-15 08:57:38","AP01EDTM":"2023-01-15 20:57:38","AP02SDTM":"2023-01-15 20:57:38","AP02EDTM":"2024-01-16 02:57:38","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-16","EOSDY":1096,"LSTALVDT":"2024-01-26","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6737,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.11317,"AVALU":"mg/L","BASE2":10.54483,"BASE":9.50242,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.43166,"PCHG2":-13.57685,"CHG":-0.38925,"PCHG":-4.09632,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-22 08:57:38","ADY":431,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-236","SUBJID":"id-236","SITEID":"BRA-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.663,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 08:57:38","TRTEDTM":"2024-01-16 02:57:38","TRT01SDTM":"2021-01-15 08:57:38","TRT01EDTM":"2023-01-15 20:57:38","TRT02SDTM":"2023-01-15 20:57:38","TRT02EDTM":"2024-01-16 02:57:38","AP01SDTM":"2021-01-15 08:57:38","AP01EDTM":"2023-01-15 20:57:38","AP02SDTM":"2023-01-15 20:57:38","AP02EDTM":"2024-01-16 02:57:38","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-16","EOSDY":1096,"LSTALVDT":"2024-01-26","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6053,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.09947,"AVALU":"mg/L","BASE2":10.54483,"BASE":9.50242,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.44536,"PCHG2":-13.70679,"CHG":-0.40295,"PCHG":-4.24052,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-07 08:57:38","ADY":781,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-236","SUBJID":"id-236","SITEID":"BRA-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.663,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 08:57:38","TRTEDTM":"2024-01-16 02:57:38","TRT01SDTM":"2021-01-15 08:57:38","TRT01EDTM":"2023-01-15 20:57:38","TRT02SDTM":"2023-01-15 20:57:38","TRT02EDTM":"2024-01-16 02:57:38","AP01SDTM":"2021-01-15 08:57:38","AP01EDTM":"2023-01-15 20:57:38","AP02SDTM":"2023-01-15 20:57:38","AP02EDTM":"2024-01-16 02:57:38","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-16","EOSDY":1096,"LSTALVDT":"2024-01-26","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5047,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.98659,"AVALU":"mg/L","BASE2":10.54483,"BASE":9.50242,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.44176,"PCHG2":4.18934,"CHG":1.48416,"PCHG":15.6188,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2023-03-20 08:57:38","ADY":794,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-236","SUBJID":"id-236","SITEID":"BRA-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.663,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 08:57:38","TRTEDTM":"2024-01-16 02:57:38","TRT01SDTM":"2021-01-15 08:57:38","TRT01EDTM":"2023-01-15 20:57:38","TRT02SDTM":"2023-01-15 20:57:38","TRT02EDTM":"2024-01-16 02:57:38","AP01SDTM":"2021-01-15 08:57:38","AP01EDTM":"2023-01-15 20:57:38","AP02SDTM":"2023-01-15 20:57:38","AP02EDTM":"2024-01-16 02:57:38","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-16","EOSDY":1096,"LSTALVDT":"2024-01-26","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6941,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.32844,"AVALU":"mg/L","BASE2":10.54483,"BASE":9.50242,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.21639,"PCHG2":-11.53543,"CHG":-0.17399,"PCHG":-1.83096,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-30 08:57:38","ADY":988,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-236","SUBJID":"id-236","SITEID":"BRA-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.663,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 08:57:38","TRTEDTM":"2024-01-16 02:57:38","TRT01SDTM":"2021-01-15 08:57:38","TRT01EDTM":"2023-01-15 20:57:38","TRT02SDTM":"2023-01-15 20:57:38","TRT02EDTM":"2024-01-16 02:57:38","AP01SDTM":"2021-01-15 08:57:38","AP01EDTM":"2023-01-15 20:57:38","AP02SDTM":"2023-01-15 20:57:38","AP02EDTM":"2024-01-16 02:57:38","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-16","EOSDY":1096,"LSTALVDT":"2024-01-26","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":265,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.37891,"AVALU":"mg/L","BASE2":10.54483,"BASE":9.50242,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16592,"PCHG2":-1.57344,"CHG":0.87649,"PCHG":9.22385,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2023-11-15 08:57:38","ADY":1034,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-236","SUBJID":"id-236","SITEID":"BRA-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.663,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 08:57:38","TRTEDTM":"2024-01-16 02:57:38","TRT01SDTM":"2021-01-15 08:57:38","TRT01EDTM":"2023-01-15 20:57:38","TRT02SDTM":"2023-01-15 20:57:38","TRT02EDTM":"2024-01-16 02:57:38","AP01SDTM":"2021-01-15 08:57:38","AP01EDTM":"2023-01-15 20:57:38","AP02SDTM":"2023-01-15 20:57:38","AP02EDTM":"2024-01-16 02:57:38","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-16","EOSDY":1096,"LSTALVDT":"2024-01-26","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6052,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04868,"AVALU":"g/L","BASE2":3.04868,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-01-27 08:57:38","ADY":12,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-236","SUBJID":"id-236","SITEID":"BRA-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.663,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 08:57:38","TRTEDTM":"2024-01-16 02:57:38","TRT01SDTM":"2021-01-15 08:57:38","TRT01EDTM":"2023-01-15 20:57:38","TRT02SDTM":"2023-01-15 20:57:38","TRT02EDTM":"2024-01-16 02:57:38","AP01SDTM":"2021-01-15 08:57:38","AP01EDTM":"2023-01-15 20:57:38","AP02SDTM":"2023-01-15 20:57:38","AP02EDTM":"2024-01-16 02:57:38","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-16","EOSDY":1096,"LSTALVDT":"2024-01-26","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6934,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84937,"AVALU":"g/L","BASE2":3.04868,"BASE":2.84937,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.19931,"PCHG2":-6.53758,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-17 08:57:38","ADY":275,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-236","SUBJID":"id-236","SITEID":"BRA-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.663,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 08:57:38","TRTEDTM":"2024-01-16 02:57:38","TRT01SDTM":"2021-01-15 08:57:38","TRT01EDTM":"2023-01-15 20:57:38","TRT02SDTM":"2023-01-15 20:57:38","TRT02EDTM":"2024-01-16 02:57:38","AP01SDTM":"2021-01-15 08:57:38","AP01EDTM":"2023-01-15 20:57:38","AP02SDTM":"2023-01-15 20:57:38","AP02EDTM":"2024-01-16 02:57:38","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-16","EOSDY":1096,"LSTALVDT":"2024-01-26","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2783,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8847,"AVALU":"g/L","BASE2":3.04868,"BASE":2.84937,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16398,"PCHG2":-5.37883,"CHG":0.03533,"PCHG":1.2398,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-22 08:57:38","ADY":431,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-236","SUBJID":"id-236","SITEID":"BRA-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.663,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 08:57:38","TRTEDTM":"2024-01-16 02:57:38","TRT01SDTM":"2021-01-15 08:57:38","TRT01EDTM":"2023-01-15 20:57:38","TRT02SDTM":"2023-01-15 20:57:38","TRT02EDTM":"2024-01-16 02:57:38","AP01SDTM":"2021-01-15 08:57:38","AP01EDTM":"2023-01-15 20:57:38","AP02SDTM":"2023-01-15 20:57:38","AP02EDTM":"2024-01-16 02:57:38","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-16","EOSDY":1096,"LSTALVDT":"2024-01-26","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7619,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82264,"AVALU":"g/L","BASE2":3.04868,"BASE":2.84937,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.22604,"PCHG2":-7.41447,"CHG":-0.02673,"PCHG":-0.93823,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-07 08:57:38","ADY":781,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-236","SUBJID":"id-236","SITEID":"BRA-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.663,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 08:57:38","TRTEDTM":"2024-01-16 02:57:38","TRT01SDTM":"2021-01-15 08:57:38","TRT01EDTM":"2023-01-15 20:57:38","TRT02SDTM":"2023-01-15 20:57:38","TRT02EDTM":"2024-01-16 02:57:38","AP01SDTM":"2021-01-15 08:57:38","AP01EDTM":"2023-01-15 20:57:38","AP02SDTM":"2023-01-15 20:57:38","AP02EDTM":"2024-01-16 02:57:38","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-16","EOSDY":1096,"LSTALVDT":"2024-01-26","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":992,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80263,"AVALU":"g/L","BASE2":3.04868,"BASE":2.84937,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.24606,"PCHG2":-8.07087,"CHG":-0.04675,"PCHG":-1.64055,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-20 08:57:38","ADY":794,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-236","SUBJID":"id-236","SITEID":"BRA-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.663,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 08:57:38","TRTEDTM":"2024-01-16 02:57:38","TRT01SDTM":"2021-01-15 08:57:38","TRT01EDTM":"2023-01-15 20:57:38","TRT02SDTM":"2023-01-15 20:57:38","TRT02EDTM":"2024-01-16 02:57:38","AP01SDTM":"2021-01-15 08:57:38","AP01EDTM":"2023-01-15 20:57:38","AP02SDTM":"2023-01-15 20:57:38","AP02EDTM":"2024-01-16 02:57:38","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-16","EOSDY":1096,"LSTALVDT":"2024-01-26","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5295,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.71277,"AVALU":"g/L","BASE2":3.04868,"BASE":2.84937,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.33591,"PCHG2":-11.01832,"CHG":-0.1366,"PCHG":-4.79416,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-30 08:57:38","ADY":988,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-236","SUBJID":"id-236","SITEID":"BRA-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.663,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 08:57:38","TRTEDTM":"2024-01-16 02:57:38","TRT01SDTM":"2021-01-15 08:57:38","TRT01EDTM":"2023-01-15 20:57:38","TRT02SDTM":"2023-01-15 20:57:38","TRT02EDTM":"2024-01-16 02:57:38","AP01SDTM":"2021-01-15 08:57:38","AP01EDTM":"2023-01-15 20:57:38","AP02SDTM":"2023-01-15 20:57:38","AP02EDTM":"2024-01-16 02:57:38","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-16","EOSDY":1096,"LSTALVDT":"2024-01-26","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6920,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99421,"AVALU":"g/L","BASE2":3.04868,"BASE":2.84937,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05447,"PCHG2":-1.78657,"CHG":0.14484,"PCHG":5.08334,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-11-15 08:57:38","ADY":1034,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-265","SUBJID":"id-265","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":10.32335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-03","TRTSDTM":"2019-10-07 15:08:39","TRTEDTM":"2022-02-16 14:03:39","TRT01SDTM":"2019-10-07 15:08:39","TRT01EDTM":"2021-02-16 08:03:39","TRT02SDTM":"2021-02-16 08:03:39","TRT02EDTM":"2022-02-16 14:03:39","AP01SDTM":"2019-10-07 15:08:39","AP01EDTM":"2021-02-16 08:03:39","AP02SDTM":"2021-02-16 08:03:39","AP02EDTM":"2022-02-16 14:03:39","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":863,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":872,"ADTHAUT":"No","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":752,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.32282,"AVALU":"U/L","BASE2":32.32282,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-17 15:08:39","ADY":41,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-265","SUBJID":"id-265","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":10.32335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-03","TRTSDTM":"2019-10-07 15:08:39","TRTEDTM":"2022-02-16 14:03:39","TRT01SDTM":"2019-10-07 15:08:39","TRT01EDTM":"2021-02-16 08:03:39","TRT02SDTM":"2021-02-16 08:03:39","TRT02EDTM":"2022-02-16 14:03:39","AP01SDTM":"2019-10-07 15:08:39","AP01EDTM":"2021-02-16 08:03:39","AP02SDTM":"2021-02-16 08:03:39","AP02EDTM":"2022-02-16 14:03:39","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":863,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":872,"ADTHAUT":"No","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3845,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.43845,"AVALU":"U/L","BASE2":32.32282,"BASE":20.43845,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-11.88438,"PCHG2":-36.76775,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-26 15:08:39","ADY":536,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-265","SUBJID":"id-265","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":10.32335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-03","TRTSDTM":"2019-10-07 15:08:39","TRTEDTM":"2022-02-16 14:03:39","TRT01SDTM":"2019-10-07 15:08:39","TRT01EDTM":"2021-02-16 08:03:39","TRT02SDTM":"2021-02-16 08:03:39","TRT02EDTM":"2022-02-16 14:03:39","AP01SDTM":"2019-10-07 15:08:39","AP01EDTM":"2021-02-16 08:03:39","AP02SDTM":"2021-02-16 08:03:39","AP02EDTM":"2022-02-16 14:03:39","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":863,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":872,"ADTHAUT":"No","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3104,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.79629,"AVALU":"U/L","BASE2":32.32282,"BASE":20.43845,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-21.52653,"PCHG2":-66.59855,"CHG":-9.64215,"PCHG":-47.17656,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-11 15:08:39","ADY":582,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-265","SUBJID":"id-265","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":10.32335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-03","TRTSDTM":"2019-10-07 15:08:39","TRTEDTM":"2022-02-16 14:03:39","TRT01SDTM":"2019-10-07 15:08:39","TRT01EDTM":"2021-02-16 08:03:39","TRT02SDTM":"2021-02-16 08:03:39","TRT02EDTM":"2022-02-16 14:03:39","AP01SDTM":"2019-10-07 15:08:39","AP01EDTM":"2021-02-16 08:03:39","AP02SDTM":"2021-02-16 08:03:39","AP02EDTM":"2022-02-16 14:03:39","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":863,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":872,"ADTHAUT":"No","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6156,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.03328,"AVALU":"U/L","BASE2":32.32282,"BASE":20.43845,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-25.28954,"PCHG2":-78.24052,"CHG":-13.40517,"PCHG":-65.588,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-08 15:08:39","ADY":671,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-265","SUBJID":"id-265","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":10.32335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-03","TRTSDTM":"2019-10-07 15:08:39","TRTEDTM":"2022-02-16 14:03:39","TRT01SDTM":"2019-10-07 15:08:39","TRT01EDTM":"2021-02-16 08:03:39","TRT02SDTM":"2021-02-16 08:03:39","TRT02EDTM":"2022-02-16 14:03:39","AP01SDTM":"2019-10-07 15:08:39","AP01EDTM":"2021-02-16 08:03:39","AP02SDTM":"2021-02-16 08:03:39","AP02EDTM":"2022-02-16 14:03:39","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":863,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":872,"ADTHAUT":"No","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4678,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.74773,"AVALU":"U/L","BASE2":32.32282,"BASE":20.43845,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-23.57509,"PCHG2":-72.93635,"CHG":-11.69071,"PCHG":-57.19961,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-05 15:08:39","ADY":699,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-265","SUBJID":"id-265","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":10.32335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-03","TRTSDTM":"2019-10-07 15:08:39","TRTEDTM":"2022-02-16 14:03:39","TRT01SDTM":"2019-10-07 15:08:39","TRT01EDTM":"2021-02-16 08:03:39","TRT02SDTM":"2021-02-16 08:03:39","TRT02EDTM":"2022-02-16 14:03:39","AP01SDTM":"2019-10-07 15:08:39","AP01EDTM":"2021-02-16 08:03:39","AP02SDTM":"2021-02-16 08:03:39","AP02EDTM":"2022-02-16 14:03:39","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":863,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":872,"ADTHAUT":"No","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5467,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.09417,"AVALU":"U/L","BASE2":32.32282,"BASE":20.43845,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.22865,"PCHG2":-0.7074,"CHG":11.65572,"PCHG":57.02842,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-10 15:08:39","ADY":704,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-265","SUBJID":"id-265","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":10.32335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-03","TRTSDTM":"2019-10-07 15:08:39","TRTEDTM":"2022-02-16 14:03:39","TRT01SDTM":"2019-10-07 15:08:39","TRT01EDTM":"2021-02-16 08:03:39","TRT02SDTM":"2021-02-16 08:03:39","TRT02EDTM":"2022-02-16 14:03:39","AP01SDTM":"2019-10-07 15:08:39","AP01EDTM":"2021-02-16 08:03:39","AP02SDTM":"2021-02-16 08:03:39","AP02EDTM":"2022-02-16 14:03:39","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":863,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":872,"ADTHAUT":"No","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4812,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.78918,"AVALU":"U/L","BASE2":32.32282,"BASE":20.43845,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.53365,"PCHG2":-44.96404,"CHG":-2.64927,"PCHG":-12.96219,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-29 15:08:39","ADY":723,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-265","SUBJID":"id-265","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":10.32335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-03","TRTSDTM":"2019-10-07 15:08:39","TRTEDTM":"2022-02-16 14:03:39","TRT01SDTM":"2019-10-07 15:08:39","TRT01EDTM":"2021-02-16 08:03:39","TRT02SDTM":"2021-02-16 08:03:39","TRT02EDTM":"2022-02-16 14:03:39","AP01SDTM":"2019-10-07 15:08:39","AP01EDTM":"2021-02-16 08:03:39","AP02SDTM":"2021-02-16 08:03:39","AP02EDTM":"2022-02-16 14:03:39","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":863,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":872,"ADTHAUT":"No","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5580,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.12786,"AVALU":"mg/L","BASE2":10.12786,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2019-11-17 15:08:39","ADY":41,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-265","SUBJID":"id-265","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":10.32335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-03","TRTSDTM":"2019-10-07 15:08:39","TRTEDTM":"2022-02-16 14:03:39","TRT01SDTM":"2019-10-07 15:08:39","TRT01EDTM":"2021-02-16 08:03:39","TRT02SDTM":"2021-02-16 08:03:39","TRT02EDTM":"2022-02-16 14:03:39","AP01SDTM":"2019-10-07 15:08:39","AP01EDTM":"2021-02-16 08:03:39","AP02SDTM":"2021-02-16 08:03:39","AP02EDTM":"2022-02-16 14:03:39","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":863,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":872,"ADTHAUT":"No","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8348,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.52482,"AVALU":"mg/L","BASE2":10.12786,"BASE":8.52482,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.60305,"PCHG2":-15.82811,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-26 15:08:39","ADY":536,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-265","SUBJID":"id-265","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":10.32335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-03","TRTSDTM":"2019-10-07 15:08:39","TRTEDTM":"2022-02-16 14:03:39","TRT01SDTM":"2019-10-07 15:08:39","TRT01EDTM":"2021-02-16 08:03:39","TRT02SDTM":"2021-02-16 08:03:39","TRT02EDTM":"2022-02-16 14:03:39","AP01SDTM":"2019-10-07 15:08:39","AP01EDTM":"2021-02-16 08:03:39","AP02SDTM":"2021-02-16 08:03:39","AP02EDTM":"2022-02-16 14:03:39","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":863,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":872,"ADTHAUT":"No","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7192,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.43996,"AVALU":"mg/L","BASE2":10.12786,"BASE":8.52482,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.6879,"PCHG2":-26.53967,"CHG":-1.08485,"PCHG":-12.72582,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-05-11 15:08:39","ADY":582,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-265","SUBJID":"id-265","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":10.32335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-03","TRTSDTM":"2019-10-07 15:08:39","TRTEDTM":"2022-02-16 14:03:39","TRT01SDTM":"2019-10-07 15:08:39","TRT01EDTM":"2021-02-16 08:03:39","TRT02SDTM":"2021-02-16 08:03:39","TRT02EDTM":"2022-02-16 14:03:39","AP01SDTM":"2019-10-07 15:08:39","AP01EDTM":"2021-02-16 08:03:39","AP02SDTM":"2021-02-16 08:03:39","AP02EDTM":"2022-02-16 14:03:39","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":863,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":872,"ADTHAUT":"No","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":389,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.23313,"AVALU":"mg/L","BASE2":10.12786,"BASE":8.52482,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.89474,"PCHG2":-28.58192,"CHG":-1.29169,"PCHG":-15.15211,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-08-08 15:08:39","ADY":671,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-265","SUBJID":"id-265","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":10.32335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-03","TRTSDTM":"2019-10-07 15:08:39","TRTEDTM":"2022-02-16 14:03:39","TRT01SDTM":"2019-10-07 15:08:39","TRT01EDTM":"2021-02-16 08:03:39","TRT02SDTM":"2021-02-16 08:03:39","TRT02EDTM":"2022-02-16 14:03:39","AP01SDTM":"2019-10-07 15:08:39","AP01EDTM":"2021-02-16 08:03:39","AP02SDTM":"2021-02-16 08:03:39","AP02EDTM":"2022-02-16 14:03:39","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":863,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":872,"ADTHAUT":"No","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6718,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.24024,"AVALU":"mg/L","BASE2":10.12786,"BASE":8.52482,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.88763,"PCHG2":-8.76422,"CHG":0.71542,"PCHG":8.39222,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-05 15:08:39","ADY":699,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-265","SUBJID":"id-265","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":10.32335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-03","TRTSDTM":"2019-10-07 15:08:39","TRTEDTM":"2022-02-16 14:03:39","TRT01SDTM":"2019-10-07 15:08:39","TRT01EDTM":"2021-02-16 08:03:39","TRT02SDTM":"2021-02-16 08:03:39","TRT02EDTM":"2022-02-16 14:03:39","AP01SDTM":"2019-10-07 15:08:39","AP01EDTM":"2021-02-16 08:03:39","AP02SDTM":"2021-02-16 08:03:39","AP02EDTM":"2022-02-16 14:03:39","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":863,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":872,"ADTHAUT":"No","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7559,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.46632,"AVALU":"mg/L","BASE2":10.12786,"BASE":8.52482,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.66154,"PCHG2":-6.53192,"CHG":0.94151,"PCHG":11.04429,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-10 15:08:39","ADY":704,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-265","SUBJID":"id-265","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":10.32335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-03","TRTSDTM":"2019-10-07 15:08:39","TRTEDTM":"2022-02-16 14:03:39","TRT01SDTM":"2019-10-07 15:08:39","TRT01EDTM":"2021-02-16 08:03:39","TRT02SDTM":"2021-02-16 08:03:39","TRT02EDTM":"2022-02-16 14:03:39","AP01SDTM":"2019-10-07 15:08:39","AP01EDTM":"2021-02-16 08:03:39","AP02SDTM":"2021-02-16 08:03:39","AP02EDTM":"2022-02-16 14:03:39","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":863,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":872,"ADTHAUT":"No","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2768,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.9388,"AVALU":"mg/L","BASE2":10.12786,"BASE":8.52482,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18906,"PCHG2":-1.86673,"CHG":1.41399,"PCHG":16.58675,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-29 15:08:39","ADY":723,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-265","SUBJID":"id-265","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":10.32335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-03","TRTSDTM":"2019-10-07 15:08:39","TRTEDTM":"2022-02-16 14:03:39","TRT01SDTM":"2019-10-07 15:08:39","TRT01EDTM":"2021-02-16 08:03:39","TRT02SDTM":"2021-02-16 08:03:39","TRT02EDTM":"2022-02-16 14:03:39","AP01SDTM":"2019-10-07 15:08:39","AP01EDTM":"2021-02-16 08:03:39","AP02SDTM":"2021-02-16 08:03:39","AP02EDTM":"2022-02-16 14:03:39","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":863,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":872,"ADTHAUT":"No","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2485,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90073,"AVALU":"g/L","BASE2":2.90073,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-17 15:08:39","ADY":41,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-265","SUBJID":"id-265","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":10.32335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-03","TRTSDTM":"2019-10-07 15:08:39","TRTEDTM":"2022-02-16 14:03:39","TRT01SDTM":"2019-10-07 15:08:39","TRT01EDTM":"2021-02-16 08:03:39","TRT02SDTM":"2021-02-16 08:03:39","TRT02EDTM":"2022-02-16 14:03:39","AP01SDTM":"2019-10-07 15:08:39","AP01EDTM":"2021-02-16 08:03:39","AP02SDTM":"2021-02-16 08:03:39","AP02EDTM":"2022-02-16 14:03:39","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":863,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":872,"ADTHAUT":"No","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":192,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95916,"AVALU":"g/L","BASE2":2.90073,"BASE":2.95916,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.05842,"PCHG2":2.0141,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-26 15:08:39","ADY":536,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-265","SUBJID":"id-265","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":10.32335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-03","TRTSDTM":"2019-10-07 15:08:39","TRTEDTM":"2022-02-16 14:03:39","TRT01SDTM":"2019-10-07 15:08:39","TRT01EDTM":"2021-02-16 08:03:39","TRT02SDTM":"2021-02-16 08:03:39","TRT02EDTM":"2022-02-16 14:03:39","AP01SDTM":"2019-10-07 15:08:39","AP01EDTM":"2021-02-16 08:03:39","AP02SDTM":"2021-02-16 08:03:39","AP02EDTM":"2022-02-16 14:03:39","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":863,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":872,"ADTHAUT":"No","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5738,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93959,"AVALU":"g/L","BASE2":2.90073,"BASE":2.95916,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03885,"PCHG2":1.33937,"CHG":-0.01957,"PCHG":-0.66141,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-11 15:08:39","ADY":582,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-265","SUBJID":"id-265","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":10.32335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-03","TRTSDTM":"2019-10-07 15:08:39","TRTEDTM":"2022-02-16 14:03:39","TRT01SDTM":"2019-10-07 15:08:39","TRT01EDTM":"2021-02-16 08:03:39","TRT02SDTM":"2021-02-16 08:03:39","TRT02EDTM":"2022-02-16 14:03:39","AP01SDTM":"2019-10-07 15:08:39","AP01EDTM":"2021-02-16 08:03:39","AP02SDTM":"2021-02-16 08:03:39","AP02EDTM":"2022-02-16 14:03:39","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":863,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":872,"ADTHAUT":"No","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":22,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94052,"AVALU":"g/L","BASE2":2.90073,"BASE":2.95916,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03979,"PCHG2":1.37161,"CHG":-0.01864,"PCHG":-0.62981,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-08 15:08:39","ADY":671,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-265","SUBJID":"id-265","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":10.32335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-03","TRTSDTM":"2019-10-07 15:08:39","TRTEDTM":"2022-02-16 14:03:39","TRT01SDTM":"2019-10-07 15:08:39","TRT01EDTM":"2021-02-16 08:03:39","TRT02SDTM":"2021-02-16 08:03:39","TRT02EDTM":"2022-02-16 14:03:39","AP01SDTM":"2019-10-07 15:08:39","AP01EDTM":"2021-02-16 08:03:39","AP02SDTM":"2021-02-16 08:03:39","AP02EDTM":"2022-02-16 14:03:39","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":863,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":872,"ADTHAUT":"No","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4187,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84967,"AVALU":"g/L","BASE2":2.90073,"BASE":2.95916,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05106,"PCHG2":-1.76039,"CHG":-0.10949,"PCHG":-3.69997,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-05 15:08:39","ADY":699,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-265","SUBJID":"id-265","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":10.32335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-03","TRTSDTM":"2019-10-07 15:08:39","TRTEDTM":"2022-02-16 14:03:39","TRT01SDTM":"2019-10-07 15:08:39","TRT01EDTM":"2021-02-16 08:03:39","TRT02SDTM":"2021-02-16 08:03:39","TRT02EDTM":"2022-02-16 14:03:39","AP01SDTM":"2019-10-07 15:08:39","AP01EDTM":"2021-02-16 08:03:39","AP02SDTM":"2021-02-16 08:03:39","AP02EDTM":"2022-02-16 14:03:39","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":863,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":872,"ADTHAUT":"No","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":395,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.68766,"AVALU":"g/L","BASE2":2.90073,"BASE":2.95916,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21307,"PCHG2":-7.34554,"CHG":-0.2715,"PCHG":-9.17485,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-10 15:08:39","ADY":704,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-265","SUBJID":"id-265","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":10.32335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-03","TRTSDTM":"2019-10-07 15:08:39","TRTEDTM":"2022-02-16 14:03:39","TRT01SDTM":"2019-10-07 15:08:39","TRT01EDTM":"2021-02-16 08:03:39","TRT02SDTM":"2021-02-16 08:03:39","TRT02EDTM":"2022-02-16 14:03:39","AP01SDTM":"2019-10-07 15:08:39","AP01EDTM":"2021-02-16 08:03:39","AP02SDTM":"2021-02-16 08:03:39","AP02EDTM":"2022-02-16 14:03:39","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":863,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":872,"ADTHAUT":"No","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":947,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89025,"AVALU":"g/L","BASE2":2.90073,"BASE":2.95916,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01048,"PCHG2":-0.36127,"CHG":-0.0689,"PCHG":-2.32848,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-29 15:08:39","ADY":723,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-42","SUBJID":"id-42","SITEID":"BRA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":2.26754,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-12-31","TRTSDTM":"2020-01-01 21:17:58","TRT01SDTM":"2020-01-01 21:17:58","AP01SDTM":"2020-01-01 21:17:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4000,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.556,"AVALU":"U/L","BASE2":16.556,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-25 21:17:58","ADY":176,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-42","SUBJID":"id-42","SITEID":"BRA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":2.26754,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-12-31","TRTSDTM":"2020-01-01 21:17:58","TRT01SDTM":"2020-01-01 21:17:58","AP01SDTM":"2020-01-01 21:17:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1524,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.49356,"AVALU":"U/L","BASE2":16.556,"BASE":16.49356,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.06244,"PCHG2":-0.37715,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-22 21:17:58","ADY":477,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-42","SUBJID":"id-42","SITEID":"BRA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":2.26754,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-12-31","TRTSDTM":"2020-01-01 21:17:58","TRT01SDTM":"2020-01-01 21:17:58","AP01SDTM":"2020-01-01 21:17:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5184,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.71185,"AVALU":"U/L","BASE2":16.556,"BASE":16.49356,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.15584,"PCHG2":13.02152,"CHG":2.21828,"PCHG":13.44939,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-18 21:17:58","ADY":534,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-42","SUBJID":"id-42","SITEID":"BRA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":2.26754,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-12-31","TRTSDTM":"2020-01-01 21:17:58","TRT01SDTM":"2020-01-01 21:17:58","AP01SDTM":"2020-01-01 21:17:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6843,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.43908,"AVALU":"U/L","BASE2":16.556,"BASE":16.49356,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.11693,"PCHG2":-30.90678,"CHG":-5.05449,"PCHG":-30.64521,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-04 21:17:58","ADY":550,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-42","SUBJID":"id-42","SITEID":"BRA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":2.26754,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-12-31","TRTSDTM":"2020-01-01 21:17:58","TRT01SDTM":"2020-01-01 21:17:58","AP01SDTM":"2020-01-01 21:17:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1855,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.65981,"AVALU":"U/L","BASE2":16.556,"BASE":16.49356,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.10381,"PCHG2":30.82752,"CHG":5.16625,"PCHG":31.3228,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-23 21:17:58","ADY":569,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-42","SUBJID":"id-42","SITEID":"BRA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":2.26754,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-12-31","TRTSDTM":"2020-01-01 21:17:58","TRT01SDTM":"2020-01-01 21:17:58","AP01SDTM":"2020-01-01 21:17:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6833,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.60911,"AVALU":"U/L","BASE2":16.556,"BASE":16.49356,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.05311,"PCHG2":48.64163,"CHG":8.11555,"PCHG":49.20435,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-31 21:17:58","ADY":608,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-42","SUBJID":"id-42","SITEID":"BRA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":2.26754,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-12-31","TRTSDTM":"2020-01-01 21:17:58","TRT01SDTM":"2020-01-01 21:17:58","AP01SDTM":"2020-01-01 21:17:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":967,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.48714,"AVALU":"U/L","BASE2":16.556,"BASE":16.49356,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.93114,"PCHG2":41.86479,"CHG":6.99358,"PCHG":42.40186,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-06 21:17:58","ADY":675,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-42","SUBJID":"id-42","SITEID":"BRA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":2.26754,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-12-31","TRTSDTM":"2020-01-01 21:17:58","TRT01SDTM":"2020-01-01 21:17:58","AP01SDTM":"2020-01-01 21:17:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3052,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.88417,"AVALU":"mg/L","BASE2":8.88417,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-25 21:17:58","ADY":176,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-42","SUBJID":"id-42","SITEID":"BRA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":2.26754,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-12-31","TRTSDTM":"2020-01-01 21:17:58","TRT01SDTM":"2020-01-01 21:17:58","AP01SDTM":"2020-01-01 21:17:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8388,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.11459,"AVALU":"mg/L","BASE2":8.88417,"BASE":8.11459,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.76958,"PCHG2":-8.66233,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-22 21:17:58","ADY":477,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-42","SUBJID":"id-42","SITEID":"BRA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":2.26754,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-12-31","TRTSDTM":"2020-01-01 21:17:58","TRT01SDTM":"2020-01-01 21:17:58","AP01SDTM":"2020-01-01 21:17:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":317,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.77997,"AVALU":"mg/L","BASE2":8.88417,"BASE":8.11459,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1042,"PCHG2":-1.17293,"CHG":0.66537,"PCHG":8.19968,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-18 21:17:58","ADY":534,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-42","SUBJID":"id-42","SITEID":"BRA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":2.26754,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-12-31","TRTSDTM":"2020-01-01 21:17:58","TRT01SDTM":"2020-01-01 21:17:58","AP01SDTM":"2020-01-01 21:17:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7893,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.52563,"AVALU":"mg/L","BASE2":8.88417,"BASE":8.11459,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.64146,"PCHG2":7.22027,"CHG":1.41104,"PCHG":17.38888,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-04 21:17:58","ADY":550,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-42","SUBJID":"id-42","SITEID":"BRA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":2.26754,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-12-31","TRTSDTM":"2020-01-01 21:17:58","TRT01SDTM":"2020-01-01 21:17:58","AP01SDTM":"2020-01-01 21:17:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2928,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.32089,"AVALU":"mg/L","BASE2":8.88417,"BASE":8.11459,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.43672,"PCHG2":16.17169,"CHG":2.2063,"PCHG":27.18924,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-07-23 21:17:58","ADY":569,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-42","SUBJID":"id-42","SITEID":"BRA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":2.26754,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-12-31","TRTSDTM":"2020-01-01 21:17:58","TRT01SDTM":"2020-01-01 21:17:58","AP01SDTM":"2020-01-01 21:17:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3992,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.95038,"AVALU":"mg/L","BASE2":8.88417,"BASE":8.11459,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.93379,"PCHG2":-10.51071,"CHG":-0.16421,"PCHG":-2.02369,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-08-31 21:17:58","ADY":608,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-42","SUBJID":"id-42","SITEID":"BRA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":2.26754,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-12-31","TRTSDTM":"2020-01-01 21:17:58","TRT01SDTM":"2020-01-01 21:17:58","AP01SDTM":"2020-01-01 21:17:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8202,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.4641,"AVALU":"mg/L","BASE2":8.88417,"BASE":8.11459,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.42007,"PCHG2":-4.72833,"CHG":0.3495,"PCHG":4.30708,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-06 21:17:58","ADY":675,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-42","SUBJID":"id-42","SITEID":"BRA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":2.26754,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-12-31","TRTSDTM":"2020-01-01 21:17:58","TRT01SDTM":"2020-01-01 21:17:58","AP01SDTM":"2020-01-01 21:17:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5365,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75078,"AVALU":"g/L","BASE2":2.75078,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-25 21:17:58","ADY":176,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-42","SUBJID":"id-42","SITEID":"BRA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":2.26754,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-12-31","TRTSDTM":"2020-01-01 21:17:58","TRT01SDTM":"2020-01-01 21:17:58","AP01SDTM":"2020-01-01 21:17:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":807,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95185,"AVALU":"g/L","BASE2":2.75078,"BASE":2.95185,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.20107,"PCHG2":7.30963,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-22 21:17:58","ADY":477,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-42","SUBJID":"id-42","SITEID":"BRA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":2.26754,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-12-31","TRTSDTM":"2020-01-01 21:17:58","TRT01SDTM":"2020-01-01 21:17:58","AP01SDTM":"2020-01-01 21:17:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3304,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95095,"AVALU":"g/L","BASE2":2.75078,"BASE":2.95185,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.20018,"PCHG2":7.27705,"CHG":-0.0009,"PCHG":-0.03036,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-18 21:17:58","ADY":534,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-42","SUBJID":"id-42","SITEID":"BRA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":2.26754,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-12-31","TRTSDTM":"2020-01-01 21:17:58","TRT01SDTM":"2020-01-01 21:17:58","AP01SDTM":"2020-01-01 21:17:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":611,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9904,"AVALU":"g/L","BASE2":2.75078,"BASE":2.95185,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.23963,"PCHG2":8.71128,"CHG":0.03856,"PCHG":1.30617,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-04 21:17:58","ADY":550,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-42","SUBJID":"id-42","SITEID":"BRA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":2.26754,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-12-31","TRTSDTM":"2020-01-01 21:17:58","TRT01SDTM":"2020-01-01 21:17:58","AP01SDTM":"2020-01-01 21:17:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5918,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00137,"AVALU":"g/L","BASE2":2.75078,"BASE":2.95185,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.25059,"PCHG2":9.10985,"CHG":0.04952,"PCHG":1.6776,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-07-23 21:17:58","ADY":569,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-42","SUBJID":"id-42","SITEID":"BRA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":2.26754,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-12-31","TRTSDTM":"2020-01-01 21:17:58","TRT01SDTM":"2020-01-01 21:17:58","AP01SDTM":"2020-01-01 21:17:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7222,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78116,"AVALU":"g/L","BASE2":2.75078,"BASE":2.95185,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03039,"PCHG2":1.10462,"CHG":-0.17069,"PCHG":-5.78234,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-31 21:17:58","ADY":608,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-42","SUBJID":"id-42","SITEID":"BRA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":2.26754,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-12-31","TRTSDTM":"2020-01-01 21:17:58","TRT01SDTM":"2020-01-01 21:17:58","AP01SDTM":"2020-01-01 21:17:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4575,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83096,"AVALU":"g/L","BASE2":2.75078,"BASE":2.95185,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08018,"PCHG2":2.9149,"CHG":-0.12089,"PCHG":-4.09537,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-06 21:17:58","ADY":675,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-65","SUBJID":"id-65","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.34092,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-15 13:00:59","TRTEDTM":"2022-07-15 07:00:59","TRT01SDTM":"2019-07-15 13:00:59","TRT01EDTM":"2021-07-15 01:00:59","TRT02SDTM":"2021-07-15 01:00:59","TRT02EDTM":"2022-07-15 07:00:59","AP01SDTM":"2019-07-15 13:00:59","AP01EDTM":"2021-07-15 01:00:59","AP02SDTM":"2021-07-15 01:00:59","AP02EDTM":"2022-07-15 07:00:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-15","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6305,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.04959,"AVALU":"U/L","BASE2":0.04959,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-02-18 13:00:59","ADY":218,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-65","SUBJID":"id-65","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.34092,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-15 13:00:59","TRTEDTM":"2022-07-15 07:00:59","TRT01SDTM":"2019-07-15 13:00:59","TRT01EDTM":"2021-07-15 01:00:59","TRT02SDTM":"2021-07-15 01:00:59","TRT02EDTM":"2022-07-15 07:00:59","AP01SDTM":"2019-07-15 13:00:59","AP01EDTM":"2021-07-15 01:00:59","AP02SDTM":"2021-07-15 01:00:59","AP02EDTM":"2022-07-15 07:00:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-15","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7416,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.33449,"AVALU":"U/L","BASE2":0.04959,"BASE":24.33449,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":24.2849,"PCHG2":48975.03612,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-01 13:00:59","ADY":230,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-65","SUBJID":"id-65","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.34092,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-15 13:00:59","TRTEDTM":"2022-07-15 07:00:59","TRT01SDTM":"2019-07-15 13:00:59","TRT01EDTM":"2021-07-15 01:00:59","TRT02SDTM":"2021-07-15 01:00:59","TRT02EDTM":"2022-07-15 07:00:59","AP01SDTM":"2019-07-15 13:00:59","AP01EDTM":"2021-07-15 01:00:59","AP02SDTM":"2021-07-15 01:00:59","AP02EDTM":"2022-07-15 07:00:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-15","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5583,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.18413,"AVALU":"U/L","BASE2":0.04959,"BASE":24.33449,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.13454,"PCHG2":16404.8157,"CHG":-16.15036,"PCHG":-66.3682,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-09 13:00:59","ADY":269,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-65","SUBJID":"id-65","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.34092,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-15 13:00:59","TRTEDTM":"2022-07-15 07:00:59","TRT01SDTM":"2019-07-15 13:00:59","TRT01EDTM":"2021-07-15 01:00:59","TRT02SDTM":"2021-07-15 01:00:59","TRT02EDTM":"2022-07-15 07:00:59","AP01SDTM":"2019-07-15 13:00:59","AP01EDTM":"2021-07-15 01:00:59","AP02SDTM":"2021-07-15 01:00:59","AP02EDTM":"2022-07-15 07:00:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-15","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2135,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.12484,"AVALU":"U/L","BASE2":0.04959,"BASE":24.33449,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.07525,"PCHG2":28385.37179,"CHG":-10.20965,"PCHG":-41.95547,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-31 13:00:59","ADY":413,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-65","SUBJID":"id-65","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.34092,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-15 13:00:59","TRTEDTM":"2022-07-15 07:00:59","TRT01SDTM":"2019-07-15 13:00:59","TRT01EDTM":"2021-07-15 01:00:59","TRT02SDTM":"2021-07-15 01:00:59","TRT02EDTM":"2022-07-15 07:00:59","AP01SDTM":"2019-07-15 13:00:59","AP01EDTM":"2021-07-15 01:00:59","AP02SDTM":"2021-07-15 01:00:59","AP02EDTM":"2022-07-15 07:00:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-15","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7558,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.85844,"AVALU":"U/L","BASE2":0.04959,"BASE":24.33449,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":24.80886,"PCHG2":50031.68914,"CHG":0.52396,"PCHG":2.15314,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-14 13:00:59","ADY":639,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-65","SUBJID":"id-65","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.34092,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-15 13:00:59","TRTEDTM":"2022-07-15 07:00:59","TRT01SDTM":"2019-07-15 13:00:59","TRT01EDTM":"2021-07-15 01:00:59","TRT02SDTM":"2021-07-15 01:00:59","TRT02EDTM":"2022-07-15 07:00:59","AP01SDTM":"2019-07-15 13:00:59","AP01EDTM":"2021-07-15 01:00:59","AP02SDTM":"2021-07-15 01:00:59","AP02EDTM":"2022-07-15 07:00:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-15","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8316,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.37609,"AVALU":"U/L","BASE2":0.04959,"BASE":24.33449,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.3265,"PCHG2":38975.50175,"CHG":-4.9584,"PCHG":-20.37601,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-15 13:00:59","ADY":762,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-65","SUBJID":"id-65","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.34092,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-15 13:00:59","TRTEDTM":"2022-07-15 07:00:59","TRT01SDTM":"2019-07-15 13:00:59","TRT01EDTM":"2021-07-15 01:00:59","TRT02SDTM":"2021-07-15 01:00:59","TRT02EDTM":"2022-07-15 07:00:59","AP01SDTM":"2019-07-15 13:00:59","AP01EDTM":"2021-07-15 01:00:59","AP02SDTM":"2021-07-15 01:00:59","AP02EDTM":"2022-07-15 07:00:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-15","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3167,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.51663,"AVALU":"U/L","BASE2":0.04959,"BASE":24.33449,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":31.46704,"PCHG2":63459.15543,"CHG":7.18214,"PCHG":29.51423,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-29 13:00:59","ADY":868,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-65","SUBJID":"id-65","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.34092,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-15 13:00:59","TRTEDTM":"2022-07-15 07:00:59","TRT01SDTM":"2019-07-15 13:00:59","TRT01EDTM":"2021-07-15 01:00:59","TRT02SDTM":"2021-07-15 01:00:59","TRT02EDTM":"2022-07-15 07:00:59","AP01SDTM":"2019-07-15 13:00:59","AP01EDTM":"2021-07-15 01:00:59","AP02SDTM":"2021-07-15 01:00:59","AP02EDTM":"2022-07-15 07:00:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-15","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3911,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.13042,"AVALU":"mg/L","BASE2":7.13042,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-02-18 13:00:59","ADY":218,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-65","SUBJID":"id-65","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.34092,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-15 13:00:59","TRTEDTM":"2022-07-15 07:00:59","TRT01SDTM":"2019-07-15 13:00:59","TRT01EDTM":"2021-07-15 01:00:59","TRT02SDTM":"2021-07-15 01:00:59","TRT02EDTM":"2022-07-15 07:00:59","AP01SDTM":"2019-07-15 13:00:59","AP01EDTM":"2021-07-15 01:00:59","AP02SDTM":"2021-07-15 01:00:59","AP02EDTM":"2022-07-15 07:00:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-15","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6358,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.03896,"AVALU":"mg/L","BASE2":7.13042,"BASE":8.03896,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.90854,"PCHG2":12.74176,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-01 13:00:59","ADY":230,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-65","SUBJID":"id-65","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.34092,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-15 13:00:59","TRTEDTM":"2022-07-15 07:00:59","TRT01SDTM":"2019-07-15 13:00:59","TRT01EDTM":"2021-07-15 01:00:59","TRT02SDTM":"2021-07-15 01:00:59","TRT02EDTM":"2022-07-15 07:00:59","AP01SDTM":"2019-07-15 13:00:59","AP01EDTM":"2021-07-15 01:00:59","AP02SDTM":"2021-07-15 01:00:59","AP02EDTM":"2022-07-15 07:00:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-15","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1199,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.05453,"AVALU":"mg/L","BASE2":7.13042,"BASE":8.03896,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.9241,"PCHG2":26.98441,"CHG":1.01556,"PCHG":12.63298,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-09 13:00:59","ADY":269,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-65","SUBJID":"id-65","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.34092,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-15 13:00:59","TRTEDTM":"2022-07-15 07:00:59","TRT01SDTM":"2019-07-15 13:00:59","TRT01EDTM":"2021-07-15 01:00:59","TRT02SDTM":"2021-07-15 01:00:59","TRT02EDTM":"2022-07-15 07:00:59","AP01SDTM":"2019-07-15 13:00:59","AP01EDTM":"2021-07-15 01:00:59","AP02SDTM":"2021-07-15 01:00:59","AP02EDTM":"2022-07-15 07:00:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-15","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1757,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.05084,"AVALU":"mg/L","BASE2":7.13042,"BASE":8.03896,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.92041,"PCHG2":12.90826,"CHG":0.01187,"PCHG":0.14768,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-31 13:00:59","ADY":413,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-65","SUBJID":"id-65","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.34092,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-15 13:00:59","TRTEDTM":"2022-07-15 07:00:59","TRT01SDTM":"2019-07-15 13:00:59","TRT01EDTM":"2021-07-15 01:00:59","TRT02SDTM":"2021-07-15 01:00:59","TRT02EDTM":"2022-07-15 07:00:59","AP01SDTM":"2019-07-15 13:00:59","AP01EDTM":"2021-07-15 01:00:59","AP02SDTM":"2021-07-15 01:00:59","AP02EDTM":"2022-07-15 07:00:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-15","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3182,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.08574,"AVALU":"mg/L","BASE2":7.13042,"BASE":8.03896,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04468,"PCHG2":-0.62666,"CHG":-0.95323,"PCHG":-11.85756,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-04-14 13:00:59","ADY":639,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-65","SUBJID":"id-65","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.34092,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-15 13:00:59","TRTEDTM":"2022-07-15 07:00:59","TRT01SDTM":"2019-07-15 13:00:59","TRT01EDTM":"2021-07-15 01:00:59","TRT02SDTM":"2021-07-15 01:00:59","TRT02EDTM":"2022-07-15 07:00:59","AP01SDTM":"2019-07-15 13:00:59","AP01EDTM":"2021-07-15 01:00:59","AP02SDTM":"2021-07-15 01:00:59","AP02EDTM":"2022-07-15 07:00:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-15","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5155,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.49121,"AVALU":"mg/L","BASE2":7.13042,"BASE":8.03896,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.36078,"PCHG2":19.0842,"CHG":0.45224,"PCHG":5.62563,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-15 13:00:59","ADY":762,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-65","SUBJID":"id-65","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.34092,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-15 13:00:59","TRTEDTM":"2022-07-15 07:00:59","TRT01SDTM":"2019-07-15 13:00:59","TRT01EDTM":"2021-07-15 01:00:59","TRT02SDTM":"2021-07-15 01:00:59","TRT02EDTM":"2022-07-15 07:00:59","AP01SDTM":"2019-07-15 13:00:59","AP01EDTM":"2021-07-15 01:00:59","AP02SDTM":"2021-07-15 01:00:59","AP02EDTM":"2022-07-15 07:00:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-15","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6899,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.4881,"AVALU":"mg/L","BASE2":7.13042,"BASE":8.03896,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.35768,"PCHG2":19.04063,"CHG":0.44914,"PCHG":5.58699,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-29 13:00:59","ADY":868,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-65","SUBJID":"id-65","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.34092,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-15 13:00:59","TRTEDTM":"2022-07-15 07:00:59","TRT01SDTM":"2019-07-15 13:00:59","TRT01EDTM":"2021-07-15 01:00:59","TRT02SDTM":"2021-07-15 01:00:59","TRT02EDTM":"2022-07-15 07:00:59","AP01SDTM":"2019-07-15 13:00:59","AP01EDTM":"2021-07-15 01:00:59","AP02SDTM":"2021-07-15 01:00:59","AP02EDTM":"2022-07-15 07:00:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-15","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":970,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83289,"AVALU":"g/L","BASE2":2.83289,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-18 13:00:59","ADY":218,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-65","SUBJID":"id-65","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.34092,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-15 13:00:59","TRTEDTM":"2022-07-15 07:00:59","TRT01SDTM":"2019-07-15 13:00:59","TRT01EDTM":"2021-07-15 01:00:59","TRT02SDTM":"2021-07-15 01:00:59","TRT02EDTM":"2022-07-15 07:00:59","AP01SDTM":"2019-07-15 13:00:59","AP01EDTM":"2021-07-15 01:00:59","AP02SDTM":"2021-07-15 01:00:59","AP02EDTM":"2022-07-15 07:00:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-15","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7329,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75341,"AVALU":"g/L","BASE2":2.83289,"BASE":2.75341,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.07947,"PCHG2":-2.80543,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-01 13:00:59","ADY":230,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-65","SUBJID":"id-65","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.34092,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-15 13:00:59","TRTEDTM":"2022-07-15 07:00:59","TRT01SDTM":"2019-07-15 13:00:59","TRT01EDTM":"2021-07-15 01:00:59","TRT02SDTM":"2021-07-15 01:00:59","TRT02EDTM":"2022-07-15 07:00:59","AP01SDTM":"2019-07-15 13:00:59","AP01EDTM":"2021-07-15 01:00:59","AP02SDTM":"2021-07-15 01:00:59","AP02EDTM":"2022-07-15 07:00:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-15","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2666,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91071,"AVALU":"g/L","BASE2":2.83289,"BASE":2.75341,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07783,"PCHG2":2.74722,"CHG":0.1573,"PCHG":5.71292,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-09 13:00:59","ADY":269,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-65","SUBJID":"id-65","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.34092,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-15 13:00:59","TRTEDTM":"2022-07-15 07:00:59","TRT01SDTM":"2019-07-15 13:00:59","TRT01EDTM":"2021-07-15 01:00:59","TRT02SDTM":"2021-07-15 01:00:59","TRT02EDTM":"2022-07-15 07:00:59","AP01SDTM":"2019-07-15 13:00:59","AP01EDTM":"2021-07-15 01:00:59","AP02SDTM":"2021-07-15 01:00:59","AP02EDTM":"2022-07-15 07:00:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-15","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4382,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77772,"AVALU":"g/L","BASE2":2.83289,"BASE":2.75341,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05516,"PCHG2":-1.9472,"CHG":0.02431,"PCHG":0.883,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-31 13:00:59","ADY":413,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-65","SUBJID":"id-65","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.34092,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-15 13:00:59","TRTEDTM":"2022-07-15 07:00:59","TRT01SDTM":"2019-07-15 13:00:59","TRT01EDTM":"2021-07-15 01:00:59","TRT02SDTM":"2021-07-15 01:00:59","TRT02EDTM":"2022-07-15 07:00:59","AP01SDTM":"2019-07-15 13:00:59","AP01EDTM":"2021-07-15 01:00:59","AP02SDTM":"2021-07-15 01:00:59","AP02EDTM":"2022-07-15 07:00:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-15","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2077,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9263,"AVALU":"g/L","BASE2":2.83289,"BASE":2.75341,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09341,"PCHG2":3.29743,"CHG":0.17289,"PCHG":6.27901,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-14 13:00:59","ADY":639,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-65","SUBJID":"id-65","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.34092,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-15 13:00:59","TRTEDTM":"2022-07-15 07:00:59","TRT01SDTM":"2019-07-15 13:00:59","TRT01EDTM":"2021-07-15 01:00:59","TRT02SDTM":"2021-07-15 01:00:59","TRT02EDTM":"2022-07-15 07:00:59","AP01SDTM":"2019-07-15 13:00:59","AP01EDTM":"2021-07-15 01:00:59","AP02SDTM":"2021-07-15 01:00:59","AP02EDTM":"2022-07-15 07:00:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-15","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4175,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78102,"AVALU":"g/L","BASE2":2.83289,"BASE":2.75341,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05187,"PCHG2":-1.83101,"CHG":0.0276,"PCHG":1.00254,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-15 13:00:59","ADY":762,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-65","SUBJID":"id-65","SITEID":"BRA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.34092,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-15 13:00:59","TRTEDTM":"2022-07-15 07:00:59","TRT01SDTM":"2019-07-15 13:00:59","TRT01EDTM":"2021-07-15 01:00:59","TRT02SDTM":"2021-07-15 01:00:59","TRT02EDTM":"2022-07-15 07:00:59","AP01SDTM":"2019-07-15 13:00:59","AP01EDTM":"2021-07-15 01:00:59","AP02SDTM":"2021-07-15 01:00:59","AP02EDTM":"2022-07-15 07:00:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-15","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2247,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96409,"AVALU":"g/L","BASE2":2.83289,"BASE":2.75341,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13121,"PCHG2":4.63155,"CHG":0.21068,"PCHG":7.65164,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-29 13:00:59","ADY":868,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-93","SUBJID":"id-93","SITEID":"BRA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.86835,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-17","TRTSDTM":"2020-06-20 06:42:30","TRTEDTM":"2022-02-19 12:31:49","TRT01SDTM":"2020-06-20 06:42:30","TRT01EDTM":"2021-02-19 06:31:49","TRT02SDTM":"2021-02-19 06:31:49","TRT02EDTM":"2022-02-19 12:31:49","AP01SDTM":"2020-06-20 06:42:30","AP01EDTM":"2021-02-19 06:31:49","AP02SDTM":"2021-02-19 06:31:49","AP02EDTM":"2022-02-19 12:31:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":610,"DCSREAS":"DEATH","DTHDT":"2022-04-09","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-09","DTHADY":657,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4979,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.68967,"AVALU":"U/L","BASE2":14.68967,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-09 06:42:30","ADY":19,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-93","SUBJID":"id-93","SITEID":"BRA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.86835,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-17","TRTSDTM":"2020-06-20 06:42:30","TRTEDTM":"2022-02-19 12:31:49","TRT01SDTM":"2020-06-20 06:42:30","TRT01EDTM":"2021-02-19 06:31:49","TRT02SDTM":"2021-02-19 06:31:49","TRT02EDTM":"2022-02-19 12:31:49","AP01SDTM":"2020-06-20 06:42:30","AP01EDTM":"2021-02-19 06:31:49","AP02SDTM":"2021-02-19 06:31:49","AP02EDTM":"2022-02-19 12:31:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":610,"DCSREAS":"DEATH","DTHDT":"2022-04-09","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-09","DTHADY":657,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2619,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.33828,"AVALU":"U/L","BASE2":14.68967,"BASE":15.33828,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.64861,"PCHG2":4.41539,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-01 06:42:30","ADY":73,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-93","SUBJID":"id-93","SITEID":"BRA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.86835,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-17","TRTSDTM":"2020-06-20 06:42:30","TRTEDTM":"2022-02-19 12:31:49","TRT01SDTM":"2020-06-20 06:42:30","TRT01EDTM":"2021-02-19 06:31:49","TRT02SDTM":"2021-02-19 06:31:49","TRT02EDTM":"2022-02-19 12:31:49","AP01SDTM":"2020-06-20 06:42:30","AP01EDTM":"2021-02-19 06:31:49","AP02SDTM":"2021-02-19 06:31:49","AP02EDTM":"2022-02-19 12:31:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":610,"DCSREAS":"DEATH","DTHDT":"2022-04-09","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-09","DTHADY":657,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3502,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.1467,"AVALU":"U/L","BASE2":14.68967,"BASE":15.33828,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.54297,"PCHG2":-58.15633,"CHG":-9.19158,"PCHG":-59.92576,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-01-13 06:42:30","ADY":207,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-93","SUBJID":"id-93","SITEID":"BRA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.86835,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-17","TRTSDTM":"2020-06-20 06:42:30","TRTEDTM":"2022-02-19 12:31:49","TRT01SDTM":"2020-06-20 06:42:30","TRT01EDTM":"2021-02-19 06:31:49","TRT02SDTM":"2021-02-19 06:31:49","TRT02EDTM":"2022-02-19 12:31:49","AP01SDTM":"2020-06-20 06:42:30","AP01EDTM":"2021-02-19 06:31:49","AP02SDTM":"2021-02-19 06:31:49","AP02EDTM":"2022-02-19 12:31:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":610,"DCSREAS":"DEATH","DTHDT":"2022-04-09","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-09","DTHADY":657,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5950,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.43847,"AVALU":"U/L","BASE2":14.68967,"BASE":15.33828,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.7488,"PCHG2":18.71246,"CHG":2.10019,"PCHG":13.69249,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-14 06:42:30","ADY":359,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-93","SUBJID":"id-93","SITEID":"BRA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.86835,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-17","TRTSDTM":"2020-06-20 06:42:30","TRTEDTM":"2022-02-19 12:31:49","TRT01SDTM":"2020-06-20 06:42:30","TRT01EDTM":"2021-02-19 06:31:49","TRT02SDTM":"2021-02-19 06:31:49","TRT02EDTM":"2022-02-19 12:31:49","AP01SDTM":"2020-06-20 06:42:30","AP01EDTM":"2021-02-19 06:31:49","AP02SDTM":"2021-02-19 06:31:49","AP02EDTM":"2022-02-19 12:31:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":610,"DCSREAS":"DEATH","DTHDT":"2022-04-09","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-09","DTHADY":657,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":613,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.13746,"AVALU":"U/L","BASE2":14.68967,"BASE":15.33828,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.44779,"PCHG2":3.04835,"CHG":-0.20081,"PCHG":-1.30924,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-28 06:42:30","ADY":373,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-93","SUBJID":"id-93","SITEID":"BRA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.86835,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-17","TRTSDTM":"2020-06-20 06:42:30","TRTEDTM":"2022-02-19 12:31:49","TRT01SDTM":"2020-06-20 06:42:30","TRT01EDTM":"2021-02-19 06:31:49","TRT02SDTM":"2021-02-19 06:31:49","TRT02EDTM":"2022-02-19 12:31:49","AP01SDTM":"2020-06-20 06:42:30","AP01EDTM":"2021-02-19 06:31:49","AP02SDTM":"2021-02-19 06:31:49","AP02EDTM":"2022-02-19 12:31:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":610,"DCSREAS":"DEATH","DTHDT":"2022-04-09","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-09","DTHADY":657,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1866,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.96646,"AVALU":"U/L","BASE2":14.68967,"BASE":15.33828,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.72321,"PCHG2":-32.15328,"CHG":-5.37182,"PCHG":-35.0223,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-16 06:42:30","ADY":422,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-93","SUBJID":"id-93","SITEID":"BRA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.86835,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-17","TRTSDTM":"2020-06-20 06:42:30","TRTEDTM":"2022-02-19 12:31:49","TRT01SDTM":"2020-06-20 06:42:30","TRT01EDTM":"2021-02-19 06:31:49","TRT02SDTM":"2021-02-19 06:31:49","TRT02EDTM":"2022-02-19 12:31:49","AP01SDTM":"2020-06-20 06:42:30","AP01EDTM":"2021-02-19 06:31:49","AP02SDTM":"2021-02-19 06:31:49","AP02EDTM":"2022-02-19 12:31:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":610,"DCSREAS":"DEATH","DTHDT":"2022-04-09","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-09","DTHADY":657,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2098,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.99248,"AVALU":"U/L","BASE2":14.68967,"BASE":15.33828,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.30281,"PCHG2":56.52141,"CHG":7.6542,"PCHG":49.90262,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-20 06:42:30","ADY":426,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-93","SUBJID":"id-93","SITEID":"BRA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.86835,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-17","TRTSDTM":"2020-06-20 06:42:30","TRTEDTM":"2022-02-19 12:31:49","TRT01SDTM":"2020-06-20 06:42:30","TRT01EDTM":"2021-02-19 06:31:49","TRT02SDTM":"2021-02-19 06:31:49","TRT02EDTM":"2022-02-19 12:31:49","AP01SDTM":"2020-06-20 06:42:30","AP01EDTM":"2021-02-19 06:31:49","AP02SDTM":"2021-02-19 06:31:49","AP02EDTM":"2022-02-19 12:31:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":610,"DCSREAS":"DEATH","DTHDT":"2022-04-09","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-09","DTHADY":657,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1828,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.15385,"AVALU":"mg/L","BASE2":9.15385,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-09 06:42:30","ADY":19,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-93","SUBJID":"id-93","SITEID":"BRA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.86835,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-17","TRTSDTM":"2020-06-20 06:42:30","TRTEDTM":"2022-02-19 12:31:49","TRT01SDTM":"2020-06-20 06:42:30","TRT01EDTM":"2021-02-19 06:31:49","TRT02SDTM":"2021-02-19 06:31:49","TRT02EDTM":"2022-02-19 12:31:49","AP01SDTM":"2020-06-20 06:42:30","AP01EDTM":"2021-02-19 06:31:49","AP02SDTM":"2021-02-19 06:31:49","AP02EDTM":"2022-02-19 12:31:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":610,"DCSREAS":"DEATH","DTHDT":"2022-04-09","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-09","DTHADY":657,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6700,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.7907,"AVALU":"mg/L","BASE2":9.15385,"BASE":8.7907,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.36315,"PCHG2":-3.96714,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-01 06:42:30","ADY":73,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-93","SUBJID":"id-93","SITEID":"BRA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.86835,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-17","TRTSDTM":"2020-06-20 06:42:30","TRTEDTM":"2022-02-19 12:31:49","TRT01SDTM":"2020-06-20 06:42:30","TRT01EDTM":"2021-02-19 06:31:49","TRT02SDTM":"2021-02-19 06:31:49","TRT02EDTM":"2022-02-19 12:31:49","AP01SDTM":"2020-06-20 06:42:30","AP01EDTM":"2021-02-19 06:31:49","AP02SDTM":"2021-02-19 06:31:49","AP02EDTM":"2022-02-19 12:31:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":610,"DCSREAS":"DEATH","DTHDT":"2022-04-09","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-09","DTHADY":657,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1027,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.82568,"AVALU":"mg/L","BASE2":9.15385,"BASE":8.7907,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.32817,"PCHG2":-25.43373,"CHG":-1.96502,"PCHG":-22.35338,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-01-13 06:42:30","ADY":207,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-93","SUBJID":"id-93","SITEID":"BRA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.86835,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-17","TRTSDTM":"2020-06-20 06:42:30","TRTEDTM":"2022-02-19 12:31:49","TRT01SDTM":"2020-06-20 06:42:30","TRT01EDTM":"2021-02-19 06:31:49","TRT02SDTM":"2021-02-19 06:31:49","TRT02EDTM":"2022-02-19 12:31:49","AP01SDTM":"2020-06-20 06:42:30","AP01EDTM":"2021-02-19 06:31:49","AP02SDTM":"2021-02-19 06:31:49","AP02EDTM":"2022-02-19 12:31:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":610,"DCSREAS":"DEATH","DTHDT":"2022-04-09","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-09","DTHADY":657,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7382,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.48957,"AVALU":"mg/L","BASE2":9.15385,"BASE":8.7907,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.66428,"PCHG2":-7.2568,"CHG":-0.30113,"PCHG":-3.42556,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-14 06:42:30","ADY":359,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-93","SUBJID":"id-93","SITEID":"BRA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.86835,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-17","TRTSDTM":"2020-06-20 06:42:30","TRTEDTM":"2022-02-19 12:31:49","TRT01SDTM":"2020-06-20 06:42:30","TRT01EDTM":"2021-02-19 06:31:49","TRT02SDTM":"2021-02-19 06:31:49","TRT02EDTM":"2022-02-19 12:31:49","AP01SDTM":"2020-06-20 06:42:30","AP01EDTM":"2021-02-19 06:31:49","AP02SDTM":"2021-02-19 06:31:49","AP02EDTM":"2022-02-19 12:31:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":610,"DCSREAS":"DEATH","DTHDT":"2022-04-09","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-09","DTHADY":657,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5181,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.25312,"AVALU":"mg/L","BASE2":9.15385,"BASE":8.7907,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.09928,"PCHG2":12.00889,"CHG":1.46242,"PCHG":16.63601,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-06-28 06:42:30","ADY":373,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-93","SUBJID":"id-93","SITEID":"BRA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.86835,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-17","TRTSDTM":"2020-06-20 06:42:30","TRTEDTM":"2022-02-19 12:31:49","TRT01SDTM":"2020-06-20 06:42:30","TRT01EDTM":"2021-02-19 06:31:49","TRT02SDTM":"2021-02-19 06:31:49","TRT02EDTM":"2022-02-19 12:31:49","AP01SDTM":"2020-06-20 06:42:30","AP01EDTM":"2021-02-19 06:31:49","AP02SDTM":"2021-02-19 06:31:49","AP02EDTM":"2022-02-19 12:31:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":610,"DCSREAS":"DEATH","DTHDT":"2022-04-09","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-09","DTHADY":657,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":552,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.48458,"AVALU":"mg/L","BASE2":9.15385,"BASE":8.7907,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.33073,"PCHG2":14.53739,"CHG":1.69388,"PCHG":19.26896,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-08-16 06:42:30","ADY":422,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-93","SUBJID":"id-93","SITEID":"BRA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.86835,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-17","TRTSDTM":"2020-06-20 06:42:30","TRTEDTM":"2022-02-19 12:31:49","TRT01SDTM":"2020-06-20 06:42:30","TRT01EDTM":"2021-02-19 06:31:49","TRT02SDTM":"2021-02-19 06:31:49","TRT02EDTM":"2022-02-19 12:31:49","AP01SDTM":"2020-06-20 06:42:30","AP01EDTM":"2021-02-19 06:31:49","AP02SDTM":"2021-02-19 06:31:49","AP02EDTM":"2022-02-19 12:31:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":610,"DCSREAS":"DEATH","DTHDT":"2022-04-09","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-09","DTHADY":657,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6592,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.92161,"AVALU":"mg/L","BASE2":9.15385,"BASE":8.7907,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.23223,"PCHG2":-24.38575,"CHG":-1.86909,"PCHG":-21.2621,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-08-20 06:42:30","ADY":426,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-93","SUBJID":"id-93","SITEID":"BRA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.86835,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-17","TRTSDTM":"2020-06-20 06:42:30","TRTEDTM":"2022-02-19 12:31:49","TRT01SDTM":"2020-06-20 06:42:30","TRT01EDTM":"2021-02-19 06:31:49","TRT02SDTM":"2021-02-19 06:31:49","TRT02EDTM":"2022-02-19 12:31:49","AP01SDTM":"2020-06-20 06:42:30","AP01EDTM":"2021-02-19 06:31:49","AP02SDTM":"2021-02-19 06:31:49","AP02EDTM":"2022-02-19 12:31:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":610,"DCSREAS":"DEATH","DTHDT":"2022-04-09","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-09","DTHADY":657,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":275,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78509,"AVALU":"g/L","BASE2":2.78509,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-07-09 06:42:30","ADY":19,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-93","SUBJID":"id-93","SITEID":"BRA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.86835,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-17","TRTSDTM":"2020-06-20 06:42:30","TRTEDTM":"2022-02-19 12:31:49","TRT01SDTM":"2020-06-20 06:42:30","TRT01EDTM":"2021-02-19 06:31:49","TRT02SDTM":"2021-02-19 06:31:49","TRT02EDTM":"2022-02-19 12:31:49","AP01SDTM":"2020-06-20 06:42:30","AP01EDTM":"2021-02-19 06:31:49","AP02SDTM":"2021-02-19 06:31:49","AP02EDTM":"2022-02-19 12:31:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":610,"DCSREAS":"DEATH","DTHDT":"2022-04-09","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-09","DTHADY":657,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3275,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02586,"AVALU":"g/L","BASE2":2.78509,"BASE":3.02586,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.24077,"PCHG2":8.64513,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2020-09-01 06:42:30","ADY":73,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-93","SUBJID":"id-93","SITEID":"BRA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.86835,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-17","TRTSDTM":"2020-06-20 06:42:30","TRTEDTM":"2022-02-19 12:31:49","TRT01SDTM":"2020-06-20 06:42:30","TRT01EDTM":"2021-02-19 06:31:49","TRT02SDTM":"2021-02-19 06:31:49","TRT02EDTM":"2022-02-19 12:31:49","AP01SDTM":"2020-06-20 06:42:30","AP01EDTM":"2021-02-19 06:31:49","AP02SDTM":"2021-02-19 06:31:49","AP02EDTM":"2022-02-19 12:31:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":610,"DCSREAS":"DEATH","DTHDT":"2022-04-09","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-09","DTHADY":657,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1592,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7028,"AVALU":"g/L","BASE2":2.78509,"BASE":3.02586,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08228,"PCHG2":-2.95441,"CHG":-0.32306,"PCHG":-10.67654,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-01-13 06:42:30","ADY":207,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-93","SUBJID":"id-93","SITEID":"BRA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.86835,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-17","TRTSDTM":"2020-06-20 06:42:30","TRTEDTM":"2022-02-19 12:31:49","TRT01SDTM":"2020-06-20 06:42:30","TRT01EDTM":"2021-02-19 06:31:49","TRT02SDTM":"2021-02-19 06:31:49","TRT02EDTM":"2022-02-19 12:31:49","AP01SDTM":"2020-06-20 06:42:30","AP01EDTM":"2021-02-19 06:31:49","AP02SDTM":"2021-02-19 06:31:49","AP02EDTM":"2022-02-19 12:31:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":610,"DCSREAS":"DEATH","DTHDT":"2022-04-09","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-09","DTHADY":657,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1752,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81176,"AVALU":"g/L","BASE2":2.78509,"BASE":3.02586,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02667,"PCHG2":0.95757,"CHG":-0.21411,"PCHG":-7.07584,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-06-14 06:42:30","ADY":359,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-93","SUBJID":"id-93","SITEID":"BRA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.86835,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-17","TRTSDTM":"2020-06-20 06:42:30","TRTEDTM":"2022-02-19 12:31:49","TRT01SDTM":"2020-06-20 06:42:30","TRT01EDTM":"2021-02-19 06:31:49","TRT02SDTM":"2021-02-19 06:31:49","TRT02EDTM":"2022-02-19 12:31:49","AP01SDTM":"2020-06-20 06:42:30","AP01EDTM":"2021-02-19 06:31:49","AP02SDTM":"2021-02-19 06:31:49","AP02EDTM":"2022-02-19 12:31:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":610,"DCSREAS":"DEATH","DTHDT":"2022-04-09","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-09","DTHADY":657,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":540,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74375,"AVALU":"g/L","BASE2":2.78509,"BASE":3.02586,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04134,"PCHG2":-1.48433,"CHG":-0.28211,"PCHG":-9.32343,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-06-28 06:42:30","ADY":373,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-93","SUBJID":"id-93","SITEID":"BRA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.86835,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-17","TRTSDTM":"2020-06-20 06:42:30","TRTEDTM":"2022-02-19 12:31:49","TRT01SDTM":"2020-06-20 06:42:30","TRT01EDTM":"2021-02-19 06:31:49","TRT02SDTM":"2021-02-19 06:31:49","TRT02EDTM":"2022-02-19 12:31:49","AP01SDTM":"2020-06-20 06:42:30","AP01EDTM":"2021-02-19 06:31:49","AP02SDTM":"2021-02-19 06:31:49","AP02EDTM":"2022-02-19 12:31:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":610,"DCSREAS":"DEATH","DTHDT":"2022-04-09","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-09","DTHADY":657,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1742,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86472,"AVALU":"g/L","BASE2":2.78509,"BASE":3.02586,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07964,"PCHG2":2.85937,"CHG":-0.16114,"PCHG":-5.32537,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-08-16 06:42:30","ADY":422,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-1-id-93","SUBJID":"id-93","SITEID":"BRA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-1","INVNAM":"Dr. BRA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.86835,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-17","TRTSDTM":"2020-06-20 06:42:30","TRTEDTM":"2022-02-19 12:31:49","TRT01SDTM":"2020-06-20 06:42:30","TRT01EDTM":"2021-02-19 06:31:49","TRT02SDTM":"2021-02-19 06:31:49","TRT02EDTM":"2022-02-19 12:31:49","AP01SDTM":"2020-06-20 06:42:30","AP01EDTM":"2021-02-19 06:31:49","AP02SDTM":"2021-02-19 06:31:49","AP02EDTM":"2022-02-19 12:31:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":610,"DCSREAS":"DEATH","DTHDT":"2022-04-09","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-09","DTHADY":657,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":615,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9106,"AVALU":"g/L","BASE2":2.78509,"BASE":3.02586,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12552,"PCHG2":4.50669,"CHG":-0.11526,"PCHG":-3.80913,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-08-20 06:42:30","ADY":426,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-171","SUBJID":"id-171","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.7018,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-01","TRTSDTM":"2019-12-03 03:13:14","TRT01SDTM":"2019-12-03 03:13:14","AP01SDTM":"2019-12-03 03:13:14","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":923,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.59394,"AVALU":"U/L","BASE2":1.59394,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-01-03 03:13:14","ADY":31,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-171","SUBJID":"id-171","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.7018,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-01","TRTSDTM":"2019-12-03 03:13:14","TRT01SDTM":"2019-12-03 03:13:14","AP01SDTM":"2019-12-03 03:13:14","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2000,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.40343,"AVALU":"U/L","BASE2":1.59394,"BASE":7.40343,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":5.80949,"PCHG2":364.47228,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-21 03:13:14","ADY":49,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-171","SUBJID":"id-171","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.7018,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-01","TRTSDTM":"2019-12-03 03:13:14","TRT01SDTM":"2019-12-03 03:13:14","AP01SDTM":"2019-12-03 03:13:14","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":586,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.60023,"AVALU":"U/L","BASE2":1.59394,"BASE":7.40343,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":17.00628,"PCHG2":1066.93045,"CHG":11.19679,"PCHG":151.23791,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-01 03:13:14","ADY":211,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-171","SUBJID":"id-171","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.7018,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-01","TRTSDTM":"2019-12-03 03:13:14","TRT01SDTM":"2019-12-03 03:13:14","AP01SDTM":"2019-12-03 03:13:14","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":60,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.35103,"AVALU":"U/L","BASE2":1.59394,"BASE":7.40343,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.75708,"PCHG2":674.87191,"CHG":4.9476,"PCHG":66.82845,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-09 03:13:14","ADY":250,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-171","SUBJID":"id-171","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.7018,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-01","TRTSDTM":"2019-12-03 03:13:14","TRT01SDTM":"2019-12-03 03:13:14","AP01SDTM":"2019-12-03 03:13:14","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2011,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.92174,"AVALU":"U/L","BASE2":1.59394,"BASE":7.40343,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.32779,"PCHG2":773.41414,"CHG":6.51831,"PCHG":88.0444,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-16 03:13:14","ADY":288,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-171","SUBJID":"id-171","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.7018,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-01","TRTSDTM":"2019-12-03 03:13:14","TRT01SDTM":"2019-12-03 03:13:14","AP01SDTM":"2019-12-03 03:13:14","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5048,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.00885,"AVALU":"U/L","BASE2":1.59394,"BASE":7.40343,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.4149,"PCHG2":904.35413,"CHG":8.60542,"PCHG":116.23554,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-23 03:13:14","ADY":325,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-171","SUBJID":"id-171","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.7018,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-01","TRTSDTM":"2019-12-03 03:13:14","TRT01SDTM":"2019-12-03 03:13:14","AP01SDTM":"2019-12-03 03:13:14","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1105,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.5073,"AVALU":"U/L","BASE2":1.59394,"BASE":7.40343,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.91336,"PCHG2":1186.57555,"CHG":13.10387,"PCHG":176.99727,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-21 03:13:14","ADY":535,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-171","SUBJID":"id-171","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.7018,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-01","TRTSDTM":"2019-12-03 03:13:14","TRT01SDTM":"2019-12-03 03:13:14","AP01SDTM":"2019-12-03 03:13:14","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2466,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.48182,"AVALU":"mg/L","BASE2":8.48182,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-03 03:13:14","ADY":31,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-171","SUBJID":"id-171","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.7018,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-01","TRTSDTM":"2019-12-03 03:13:14","TRT01SDTM":"2019-12-03 03:13:14","AP01SDTM":"2019-12-03 03:13:14","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3957,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.50356,"AVALU":"mg/L","BASE2":8.48182,"BASE":8.50356,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.02174,"PCHG2":0.2563,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-21 03:13:14","ADY":49,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-171","SUBJID":"id-171","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.7018,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-01","TRTSDTM":"2019-12-03 03:13:14","TRT01SDTM":"2019-12-03 03:13:14","AP01SDTM":"2019-12-03 03:13:14","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3612,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.94293,"AVALU":"mg/L","BASE2":8.48182,"BASE":8.50356,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.53889,"PCHG2":-6.35349,"CHG":-0.56063,"PCHG":-6.5929,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-07-01 03:13:14","ADY":211,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-171","SUBJID":"id-171","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.7018,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-01","TRTSDTM":"2019-12-03 03:13:14","TRT01SDTM":"2019-12-03 03:13:14","AP01SDTM":"2019-12-03 03:13:14","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1933,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.97636,"AVALU":"mg/L","BASE2":8.48182,"BASE":8.50356,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.49454,"PCHG2":17.62049,"CHG":1.4728,"PCHG":17.3198,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-09 03:13:14","ADY":250,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-171","SUBJID":"id-171","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.7018,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-01","TRTSDTM":"2019-12-03 03:13:14","TRT01SDTM":"2019-12-03 03:13:14","AP01SDTM":"2019-12-03 03:13:14","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1789,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.84547,"AVALU":"mg/L","BASE2":8.48182,"BASE":8.50356,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.36365,"PCHG2":4.2874,"CHG":0.34191,"PCHG":4.02079,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-16 03:13:14","ADY":288,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-171","SUBJID":"id-171","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.7018,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-01","TRTSDTM":"2019-12-03 03:13:14","TRT01SDTM":"2019-12-03 03:13:14","AP01SDTM":"2019-12-03 03:13:14","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4472,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.51996,"AVALU":"mg/L","BASE2":8.48182,"BASE":8.50356,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03814,"PCHG2":0.44962,"CHG":0.0164,"PCHG":0.19282,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-23 03:13:14","ADY":325,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-171","SUBJID":"id-171","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.7018,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-01","TRTSDTM":"2019-12-03 03:13:14","TRT01SDTM":"2019-12-03 03:13:14","AP01SDTM":"2019-12-03 03:13:14","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7471,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.06304,"AVALU":"mg/L","BASE2":8.48182,"BASE":8.50356,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.58121,"PCHG2":6.85247,"CHG":0.55948,"PCHG":6.57931,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-21 03:13:14","ADY":535,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-171","SUBJID":"id-171","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.7018,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-01","TRTSDTM":"2019-12-03 03:13:14","TRT01SDTM":"2019-12-03 03:13:14","AP01SDTM":"2019-12-03 03:13:14","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1047,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03419,"AVALU":"g/L","BASE2":3.03419,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"4","ADTM":"2020-01-03 03:13:14","ADY":31,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-171","SUBJID":"id-171","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.7018,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-01","TRTSDTM":"2019-12-03 03:13:14","TRT01SDTM":"2019-12-03 03:13:14","AP01SDTM":"2019-12-03 03:13:14","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4718,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05635,"AVALU":"g/L","BASE2":3.03419,"BASE":3.05635,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.02216,"PCHG2":0.73028,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"4","BTOXGR":"4","ADTM":"2020-01-21 03:13:14","ADY":49,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-171","SUBJID":"id-171","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.7018,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-01","TRTSDTM":"2019-12-03 03:13:14","TRT01SDTM":"2019-12-03 03:13:14","AP01SDTM":"2019-12-03 03:13:14","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5627,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88433,"AVALU":"g/L","BASE2":3.03419,"BASE":3.05635,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14986,"PCHG2":-4.93906,"CHG":-0.17202,"PCHG":-5.62824,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2020-07-01 03:13:14","ADY":211,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-171","SUBJID":"id-171","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.7018,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-01","TRTSDTM":"2019-12-03 03:13:14","TRT01SDTM":"2019-12-03 03:13:14","AP01SDTM":"2019-12-03 03:13:14","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6184,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81888,"AVALU":"g/L","BASE2":3.03419,"BASE":3.05635,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21532,"PCHG2":-7.09631,"CHG":-0.23747,"PCHG":-7.76985,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2020-08-09 03:13:14","ADY":250,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-171","SUBJID":"id-171","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.7018,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-01","TRTSDTM":"2019-12-03 03:13:14","TRT01SDTM":"2019-12-03 03:13:14","AP01SDTM":"2019-12-03 03:13:14","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1662,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8453,"AVALU":"g/L","BASE2":3.03419,"BASE":3.05635,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18889,"PCHG2":-6.22554,"CHG":-0.21105,"PCHG":-6.90539,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2020-09-16 03:13:14","ADY":288,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-171","SUBJID":"id-171","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.7018,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-01","TRTSDTM":"2019-12-03 03:13:14","TRT01SDTM":"2019-12-03 03:13:14","AP01SDTM":"2019-12-03 03:13:14","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":627,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8383,"AVALU":"g/L","BASE2":3.03419,"BASE":3.05635,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19589,"PCHG2":-6.45621,"CHG":-0.21805,"PCHG":-7.13439,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2020-10-23 03:13:14","ADY":325,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-171","SUBJID":"id-171","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":7.7018,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-01","TRTSDTM":"2019-12-03 03:13:14","TRT01SDTM":"2019-12-03 03:13:14","AP01SDTM":"2019-12-03 03:13:14","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1085,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93279,"AVALU":"g/L","BASE2":3.03419,"BASE":3.05635,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1014,"PCHG2":-3.3418,"CHG":-0.12355,"PCHG":-4.04257,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2021-05-21 03:13:14","ADY":535,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-217","SUBJID":"id-217","SITEID":"BRA-11","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":0.4056,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-28 13:03:28","TRTEDTM":"2022-02-15 04:19:26","TRT01SDTM":"2019-09-28 13:03:28","TRT01EDTM":"2021-02-14 22:19:26","TRT02SDTM":"2021-02-14 22:19:26","TRT02EDTM":"2022-02-15 04:19:26","AP01SDTM":"2019-09-28 13:03:28","AP01EDTM":"2021-02-14 22:19:26","AP02SDTM":"2021-02-14 22:19:26","AP02EDTM":"2022-02-15 04:19:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":893,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2185,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.84185,"AVALU":"U/L","BASE2":21.84185,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-21 13:03:28","ADY":146,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-217","SUBJID":"id-217","SITEID":"BRA-11","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":0.4056,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-28 13:03:28","TRTEDTM":"2022-02-15 04:19:26","TRT01SDTM":"2019-09-28 13:03:28","TRT01EDTM":"2021-02-14 22:19:26","TRT02SDTM":"2021-02-14 22:19:26","TRT02EDTM":"2022-02-15 04:19:26","AP01SDTM":"2019-09-28 13:03:28","AP01EDTM":"2021-02-14 22:19:26","AP02SDTM":"2021-02-14 22:19:26","AP02EDTM":"2022-02-15 04:19:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":893,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1649,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.47642,"AVALU":"U/L","BASE2":21.84185,"BASE":12.47642,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-9.36544,"PCHG2":-42.8784,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-13 13:03:28","ADY":320,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-217","SUBJID":"id-217","SITEID":"BRA-11","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":0.4056,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-28 13:03:28","TRTEDTM":"2022-02-15 04:19:26","TRT01SDTM":"2019-09-28 13:03:28","TRT01EDTM":"2021-02-14 22:19:26","TRT02SDTM":"2021-02-14 22:19:26","TRT02EDTM":"2022-02-15 04:19:26","AP01SDTM":"2019-09-28 13:03:28","AP01EDTM":"2021-02-14 22:19:26","AP02SDTM":"2021-02-14 22:19:26","AP02EDTM":"2022-02-15 04:19:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":893,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4950,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.25505,"AVALU":"U/L","BASE2":21.84185,"BASE":12.47642,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.5868,"PCHG2":-66.78373,"CHG":-5.22137,"PCHG":-41.8499,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-13 13:03:28","ADY":442,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-217","SUBJID":"id-217","SITEID":"BRA-11","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":0.4056,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-28 13:03:28","TRTEDTM":"2022-02-15 04:19:26","TRT01SDTM":"2019-09-28 13:03:28","TRT01EDTM":"2021-02-14 22:19:26","TRT02SDTM":"2021-02-14 22:19:26","TRT02EDTM":"2022-02-15 04:19:26","AP01SDTM":"2019-09-28 13:03:28","AP01EDTM":"2021-02-14 22:19:26","AP02SDTM":"2021-02-14 22:19:26","AP02EDTM":"2022-02-15 04:19:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":893,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6839,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.9318,"AVALU":"U/L","BASE2":21.84185,"BASE":12.47642,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.91006,"PCHG2":-31.63677,"CHG":2.45538,"PCHG":19.68017,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-15 13:03:28","ADY":656,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-217","SUBJID":"id-217","SITEID":"BRA-11","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":0.4056,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-28 13:03:28","TRTEDTM":"2022-02-15 04:19:26","TRT01SDTM":"2019-09-28 13:03:28","TRT01EDTM":"2021-02-14 22:19:26","TRT02SDTM":"2021-02-14 22:19:26","TRT02EDTM":"2022-02-15 04:19:26","AP01SDTM":"2019-09-28 13:03:28","AP01EDTM":"2021-02-14 22:19:26","AP02SDTM":"2021-02-14 22:19:26","AP02EDTM":"2022-02-15 04:19:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":893,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1753,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":41.72953,"AVALU":"U/L","BASE2":21.84185,"BASE":12.47642,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.88768,"PCHG2":91.05307,"CHG":29.25311,"PCHG":234.46726,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-20 13:03:28","ADY":692,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-217","SUBJID":"id-217","SITEID":"BRA-11","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":0.4056,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-28 13:03:28","TRTEDTM":"2022-02-15 04:19:26","TRT01SDTM":"2019-09-28 13:03:28","TRT01EDTM":"2021-02-14 22:19:26","TRT02SDTM":"2021-02-14 22:19:26","TRT02EDTM":"2022-02-15 04:19:26","AP01SDTM":"2019-09-28 13:03:28","AP01EDTM":"2021-02-14 22:19:26","AP02SDTM":"2021-02-14 22:19:26","AP02EDTM":"2022-02-15 04:19:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":893,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1456,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.22903,"AVALU":"U/L","BASE2":21.84185,"BASE":12.47642,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.61283,"PCHG2":-53.16777,"CHG":-2.24739,"PCHG":-18.0131,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-29 13:03:28","ADY":762,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-217","SUBJID":"id-217","SITEID":"BRA-11","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":0.4056,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-28 13:03:28","TRTEDTM":"2022-02-15 04:19:26","TRT01SDTM":"2019-09-28 13:03:28","TRT01EDTM":"2021-02-14 22:19:26","TRT02SDTM":"2021-02-14 22:19:26","TRT02EDTM":"2022-02-15 04:19:26","AP01SDTM":"2019-09-28 13:03:28","AP01EDTM":"2021-02-14 22:19:26","AP02SDTM":"2021-02-14 22:19:26","AP02EDTM":"2022-02-15 04:19:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":893,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1263,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.41331,"AVALU":"U/L","BASE2":21.84185,"BASE":12.47642,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.42855,"PCHG2":-34.01061,"CHG":1.93689,"PCHG":15.52439,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-18 13:03:28","ADY":843,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-217","SUBJID":"id-217","SITEID":"BRA-11","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":0.4056,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-28 13:03:28","TRTEDTM":"2022-02-15 04:19:26","TRT01SDTM":"2019-09-28 13:03:28","TRT01EDTM":"2021-02-14 22:19:26","TRT02SDTM":"2021-02-14 22:19:26","TRT02EDTM":"2022-02-15 04:19:26","AP01SDTM":"2019-09-28 13:03:28","AP01EDTM":"2021-02-14 22:19:26","AP02SDTM":"2021-02-14 22:19:26","AP02EDTM":"2022-02-15 04:19:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":893,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":783,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.13541,"AVALU":"mg/L","BASE2":9.13541,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-21 13:03:28","ADY":146,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-217","SUBJID":"id-217","SITEID":"BRA-11","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":0.4056,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-28 13:03:28","TRTEDTM":"2022-02-15 04:19:26","TRT01SDTM":"2019-09-28 13:03:28","TRT01EDTM":"2021-02-14 22:19:26","TRT02SDTM":"2021-02-14 22:19:26","TRT02EDTM":"2022-02-15 04:19:26","AP01SDTM":"2019-09-28 13:03:28","AP01EDTM":"2021-02-14 22:19:26","AP02SDTM":"2021-02-14 22:19:26","AP02EDTM":"2022-02-15 04:19:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":893,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6631,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.73879,"AVALU":"mg/L","BASE2":9.13541,"BASE":8.73879,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.39662,"PCHG2":-4.34158,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-13 13:03:28","ADY":320,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-217","SUBJID":"id-217","SITEID":"BRA-11","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":0.4056,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-28 13:03:28","TRTEDTM":"2022-02-15 04:19:26","TRT01SDTM":"2019-09-28 13:03:28","TRT01EDTM":"2021-02-14 22:19:26","TRT02SDTM":"2021-02-14 22:19:26","TRT02EDTM":"2022-02-15 04:19:26","AP01SDTM":"2019-09-28 13:03:28","AP01EDTM":"2021-02-14 22:19:26","AP02SDTM":"2021-02-14 22:19:26","AP02EDTM":"2022-02-15 04:19:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":893,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1500,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.72588,"AVALU":"mg/L","BASE2":9.13541,"BASE":8.73879,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.40953,"PCHG2":-15.42926,"CHG":-1.01291,"PCHG":-11.59091,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-12-13 13:03:28","ADY":442,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-217","SUBJID":"id-217","SITEID":"BRA-11","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":0.4056,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-28 13:03:28","TRTEDTM":"2022-02-15 04:19:26","TRT01SDTM":"2019-09-28 13:03:28","TRT01EDTM":"2021-02-14 22:19:26","TRT02SDTM":"2021-02-14 22:19:26","TRT02EDTM":"2022-02-15 04:19:26","AP01SDTM":"2019-09-28 13:03:28","AP01EDTM":"2021-02-14 22:19:26","AP02SDTM":"2021-02-14 22:19:26","AP02EDTM":"2022-02-15 04:19:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":893,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7796,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.71509,"AVALU":"mg/L","BASE2":9.13541,"BASE":8.73879,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.57968,"PCHG2":28.23823,"CHG":2.9763,"PCHG":34.05849,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2021-07-15 13:03:28","ADY":656,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-217","SUBJID":"id-217","SITEID":"BRA-11","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":0.4056,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-28 13:03:28","TRTEDTM":"2022-02-15 04:19:26","TRT01SDTM":"2019-09-28 13:03:28","TRT01EDTM":"2021-02-14 22:19:26","TRT02SDTM":"2021-02-14 22:19:26","TRT02EDTM":"2022-02-15 04:19:26","AP01SDTM":"2019-09-28 13:03:28","AP01EDTM":"2021-02-14 22:19:26","AP02SDTM":"2021-02-14 22:19:26","AP02EDTM":"2022-02-15 04:19:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":893,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":633,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.0641,"AVALU":"mg/L","BASE2":9.13541,"BASE":8.73879,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.07131,"PCHG2":-22.67338,"CHG":-1.67468,"PCHG":-19.16381,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-08-20 13:03:28","ADY":692,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-217","SUBJID":"id-217","SITEID":"BRA-11","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":0.4056,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-28 13:03:28","TRTEDTM":"2022-02-15 04:19:26","TRT01SDTM":"2019-09-28 13:03:28","TRT01EDTM":"2021-02-14 22:19:26","TRT02SDTM":"2021-02-14 22:19:26","TRT02EDTM":"2022-02-15 04:19:26","AP01SDTM":"2019-09-28 13:03:28","AP01EDTM":"2021-02-14 22:19:26","AP02SDTM":"2021-02-14 22:19:26","AP02EDTM":"2022-02-15 04:19:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":893,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5836,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.33749,"AVALU":"mg/L","BASE2":9.13541,"BASE":8.73879,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.79792,"PCHG2":-8.73433,"CHG":-0.4013,"PCHG":-4.59213,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-29 13:03:28","ADY":762,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-217","SUBJID":"id-217","SITEID":"BRA-11","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":0.4056,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-28 13:03:28","TRTEDTM":"2022-02-15 04:19:26","TRT01SDTM":"2019-09-28 13:03:28","TRT01EDTM":"2021-02-14 22:19:26","TRT02SDTM":"2021-02-14 22:19:26","TRT02EDTM":"2022-02-15 04:19:26","AP01SDTM":"2019-09-28 13:03:28","AP01EDTM":"2021-02-14 22:19:26","AP02SDTM":"2021-02-14 22:19:26","AP02EDTM":"2022-02-15 04:19:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":893,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2209,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.71354,"AVALU":"mg/L","BASE2":9.13541,"BASE":8.73879,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.57813,"PCHG2":6.32845,"CHG":0.97475,"PCHG":11.1543,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-18 13:03:28","ADY":843,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-217","SUBJID":"id-217","SITEID":"BRA-11","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":0.4056,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-28 13:03:28","TRTEDTM":"2022-02-15 04:19:26","TRT01SDTM":"2019-09-28 13:03:28","TRT01EDTM":"2021-02-14 22:19:26","TRT02SDTM":"2021-02-14 22:19:26","TRT02EDTM":"2022-02-15 04:19:26","AP01SDTM":"2019-09-28 13:03:28","AP01EDTM":"2021-02-14 22:19:26","AP02SDTM":"2021-02-14 22:19:26","AP02EDTM":"2022-02-15 04:19:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":893,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5853,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90444,"AVALU":"g/L","BASE2":2.90444,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-21 13:03:28","ADY":146,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-217","SUBJID":"id-217","SITEID":"BRA-11","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":0.4056,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-28 13:03:28","TRTEDTM":"2022-02-15 04:19:26","TRT01SDTM":"2019-09-28 13:03:28","TRT01EDTM":"2021-02-14 22:19:26","TRT02SDTM":"2021-02-14 22:19:26","TRT02EDTM":"2022-02-15 04:19:26","AP01SDTM":"2019-09-28 13:03:28","AP01EDTM":"2021-02-14 22:19:26","AP02SDTM":"2021-02-14 22:19:26","AP02EDTM":"2022-02-15 04:19:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":893,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1681,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77143,"AVALU":"g/L","BASE2":2.90444,"BASE":2.77143,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.13301,"PCHG2":-4.57943,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-13 13:03:28","ADY":320,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-217","SUBJID":"id-217","SITEID":"BRA-11","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":0.4056,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-28 13:03:28","TRTEDTM":"2022-02-15 04:19:26","TRT01SDTM":"2019-09-28 13:03:28","TRT01EDTM":"2021-02-14 22:19:26","TRT02SDTM":"2021-02-14 22:19:26","TRT02EDTM":"2022-02-15 04:19:26","AP01SDTM":"2019-09-28 13:03:28","AP01EDTM":"2021-02-14 22:19:26","AP02SDTM":"2021-02-14 22:19:26","AP02EDTM":"2022-02-15 04:19:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":893,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":748,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79486,"AVALU":"g/L","BASE2":2.90444,"BASE":2.77143,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10958,"PCHG2":-3.77299,"CHG":0.02342,"PCHG":0.84514,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-13 13:03:28","ADY":442,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-217","SUBJID":"id-217","SITEID":"BRA-11","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":0.4056,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-28 13:03:28","TRTEDTM":"2022-02-15 04:19:26","TRT01SDTM":"2019-09-28 13:03:28","TRT01EDTM":"2021-02-14 22:19:26","TRT02SDTM":"2021-02-14 22:19:26","TRT02EDTM":"2022-02-15 04:19:26","AP01SDTM":"2019-09-28 13:03:28","AP01EDTM":"2021-02-14 22:19:26","AP02SDTM":"2021-02-14 22:19:26","AP02EDTM":"2022-02-15 04:19:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":893,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7519,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93249,"AVALU":"g/L","BASE2":2.90444,"BASE":2.77143,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02805,"PCHG2":0.96567,"CHG":0.16105,"PCHG":5.81122,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-15 13:03:28","ADY":656,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-217","SUBJID":"id-217","SITEID":"BRA-11","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":0.4056,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-28 13:03:28","TRTEDTM":"2022-02-15 04:19:26","TRT01SDTM":"2019-09-28 13:03:28","TRT01EDTM":"2021-02-14 22:19:26","TRT02SDTM":"2021-02-14 22:19:26","TRT02EDTM":"2022-02-15 04:19:26","AP01SDTM":"2019-09-28 13:03:28","AP01EDTM":"2021-02-14 22:19:26","AP02SDTM":"2021-02-14 22:19:26","AP02EDTM":"2022-02-15 04:19:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":893,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4601,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81163,"AVALU":"g/L","BASE2":2.90444,"BASE":2.77143,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09281,"PCHG2":-3.19557,"CHG":0.04019,"PCHG":1.45027,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-20 13:03:28","ADY":692,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-217","SUBJID":"id-217","SITEID":"BRA-11","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":0.4056,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-28 13:03:28","TRTEDTM":"2022-02-15 04:19:26","TRT01SDTM":"2019-09-28 13:03:28","TRT01EDTM":"2021-02-14 22:19:26","TRT02SDTM":"2021-02-14 22:19:26","TRT02EDTM":"2022-02-15 04:19:26","AP01SDTM":"2019-09-28 13:03:28","AP01EDTM":"2021-02-14 22:19:26","AP02SDTM":"2021-02-14 22:19:26","AP02EDTM":"2022-02-15 04:19:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":893,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5121,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78741,"AVALU":"g/L","BASE2":2.90444,"BASE":2.77143,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11703,"PCHG2":-4.02947,"CHG":0.01597,"PCHG":0.57636,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-29 13:03:28","ADY":762,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-217","SUBJID":"id-217","SITEID":"BRA-11","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":0.4056,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-28 13:03:28","TRTEDTM":"2022-02-15 04:19:26","TRT01SDTM":"2019-09-28 13:03:28","TRT01EDTM":"2021-02-14 22:19:26","TRT02SDTM":"2021-02-14 22:19:26","TRT02EDTM":"2022-02-15 04:19:26","AP01SDTM":"2019-09-28 13:03:28","AP01EDTM":"2021-02-14 22:19:26","AP02SDTM":"2021-02-14 22:19:26","AP02EDTM":"2022-02-15 04:19:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":893,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1720,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88254,"AVALU":"g/L","BASE2":2.90444,"BASE":2.77143,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0219,"PCHG2":-0.75391,"CHG":0.11111,"PCHG":4.00912,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-18 13:03:28","ADY":843,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-237","SUBJID":"id-237","SITEID":"BRA-11","AGE":64,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.29531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-03-10","TRTSDTM":"2020-03-10 15:47:06","TRTEDTM":"2023-03-11 09:47:06","TRT01SDTM":"2020-03-10 15:47:06","TRT01EDTM":"2022-03-11 03:47:06","TRT02SDTM":"2022-03-11 03:47:06","TRT02EDTM":"2023-03-11 09:47:06","AP01SDTM":"2020-03-10 15:47:06","AP01EDTM":"2022-03-11 03:47:06","AP02SDTM":"2022-03-11 03:47:06","AP02EDTM":"2023-03-11 09:47:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-11","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5553,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.91259,"AVALU":"U/L","BASE2":14.91259,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-23 15:47:06","ADY":74,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-237","SUBJID":"id-237","SITEID":"BRA-11","AGE":64,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.29531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-03-10","TRTSDTM":"2020-03-10 15:47:06","TRTEDTM":"2023-03-11 09:47:06","TRT01SDTM":"2020-03-10 15:47:06","TRT01EDTM":"2022-03-11 03:47:06","TRT02SDTM":"2022-03-11 03:47:06","TRT02EDTM":"2023-03-11 09:47:06","AP01SDTM":"2020-03-10 15:47:06","AP01EDTM":"2022-03-11 03:47:06","AP02SDTM":"2022-03-11 03:47:06","AP02EDTM":"2023-03-11 09:47:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-11","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":63,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.72987,"AVALU":"U/L","BASE2":14.91259,"BASE":18.72987,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":3.81728,"PCHG2":25.59766,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-15 15:47:06","ADY":250,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-237","SUBJID":"id-237","SITEID":"BRA-11","AGE":64,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.29531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-03-10","TRTSDTM":"2020-03-10 15:47:06","TRTEDTM":"2023-03-11 09:47:06","TRT01SDTM":"2020-03-10 15:47:06","TRT01EDTM":"2022-03-11 03:47:06","TRT02SDTM":"2022-03-11 03:47:06","TRT02EDTM":"2023-03-11 09:47:06","AP01SDTM":"2020-03-10 15:47:06","AP01EDTM":"2022-03-11 03:47:06","AP02SDTM":"2022-03-11 03:47:06","AP02EDTM":"2023-03-11 09:47:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-11","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4778,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.80178,"AVALU":"U/L","BASE2":14.91259,"BASE":18.72987,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.88919,"PCHG2":73.02006,"CHG":7.07191,"PCHG":37.75739,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-03 15:47:06","ADY":419,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-237","SUBJID":"id-237","SITEID":"BRA-11","AGE":64,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.29531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-03-10","TRTSDTM":"2020-03-10 15:47:06","TRTEDTM":"2023-03-11 09:47:06","TRT01SDTM":"2020-03-10 15:47:06","TRT01EDTM":"2022-03-11 03:47:06","TRT02SDTM":"2022-03-11 03:47:06","TRT02EDTM":"2023-03-11 09:47:06","AP01SDTM":"2020-03-10 15:47:06","AP01EDTM":"2022-03-11 03:47:06","AP02SDTM":"2022-03-11 03:47:06","AP02EDTM":"2023-03-11 09:47:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-11","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2285,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.97225,"AVALU":"U/L","BASE2":14.91259,"BASE":18.72987,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.05965,"PCHG2":100.98613,"CHG":11.24238,"PCHG":60.02379,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-01 15:47:06","ADY":693,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-237","SUBJID":"id-237","SITEID":"BRA-11","AGE":64,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.29531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-03-10","TRTSDTM":"2020-03-10 15:47:06","TRTEDTM":"2023-03-11 09:47:06","TRT01SDTM":"2020-03-10 15:47:06","TRT01EDTM":"2022-03-11 03:47:06","TRT02SDTM":"2022-03-11 03:47:06","TRT02EDTM":"2023-03-11 09:47:06","AP01SDTM":"2020-03-10 15:47:06","AP01EDTM":"2022-03-11 03:47:06","AP02SDTM":"2022-03-11 03:47:06","AP02EDTM":"2023-03-11 09:47:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-11","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6333,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.91077,"AVALU":"U/L","BASE2":14.91259,"BASE":18.72987,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.00182,"PCHG2":-33.54094,"CHG":-8.8191,"PCHG":-47.08575,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-17 15:47:06","ADY":859,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-237","SUBJID":"id-237","SITEID":"BRA-11","AGE":64,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.29531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-03-10","TRTSDTM":"2020-03-10 15:47:06","TRTEDTM":"2023-03-11 09:47:06","TRT01SDTM":"2020-03-10 15:47:06","TRT01EDTM":"2022-03-11 03:47:06","TRT02SDTM":"2022-03-11 03:47:06","TRT02EDTM":"2023-03-11 09:47:06","AP01SDTM":"2020-03-10 15:47:06","AP01EDTM":"2022-03-11 03:47:06","AP02SDTM":"2022-03-11 03:47:06","AP02EDTM":"2023-03-11 09:47:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-11","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2925,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.19154,"AVALU":"U/L","BASE2":14.91259,"BASE":18.72987,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.72105,"PCHG2":-45.06963,"CHG":-10.53833,"PCHG":-56.26481,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-23 15:47:06","ADY":896,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-237","SUBJID":"id-237","SITEID":"BRA-11","AGE":64,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.29531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-03-10","TRTSDTM":"2020-03-10 15:47:06","TRTEDTM":"2023-03-11 09:47:06","TRT01SDTM":"2020-03-10 15:47:06","TRT01EDTM":"2022-03-11 03:47:06","TRT02SDTM":"2022-03-11 03:47:06","TRT02EDTM":"2023-03-11 09:47:06","AP01SDTM":"2020-03-10 15:47:06","AP01EDTM":"2022-03-11 03:47:06","AP02SDTM":"2022-03-11 03:47:06","AP02EDTM":"2023-03-11 09:47:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-11","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4156,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.12877,"AVALU":"U/L","BASE2":14.91259,"BASE":18.72987,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.21618,"PCHG2":128.8587,"CHG":15.3989,"PCHG":82.21574,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-15 15:47:06","ADY":1041,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-237","SUBJID":"id-237","SITEID":"BRA-11","AGE":64,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.29531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-03-10","TRTSDTM":"2020-03-10 15:47:06","TRTEDTM":"2023-03-11 09:47:06","TRT01SDTM":"2020-03-10 15:47:06","TRT01EDTM":"2022-03-11 03:47:06","TRT02SDTM":"2022-03-11 03:47:06","TRT02EDTM":"2023-03-11 09:47:06","AP01SDTM":"2020-03-10 15:47:06","AP01EDTM":"2022-03-11 03:47:06","AP02SDTM":"2022-03-11 03:47:06","AP02EDTM":"2023-03-11 09:47:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-11","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1159,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.27599,"AVALU":"mg/L","BASE2":11.27599,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-05-23 15:47:06","ADY":74,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-237","SUBJID":"id-237","SITEID":"BRA-11","AGE":64,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.29531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-03-10","TRTSDTM":"2020-03-10 15:47:06","TRTEDTM":"2023-03-11 09:47:06","TRT01SDTM":"2020-03-10 15:47:06","TRT01EDTM":"2022-03-11 03:47:06","TRT02SDTM":"2022-03-11 03:47:06","TRT02EDTM":"2023-03-11 09:47:06","AP01SDTM":"2020-03-10 15:47:06","AP01EDTM":"2022-03-11 03:47:06","AP02SDTM":"2022-03-11 03:47:06","AP02EDTM":"2023-03-11 09:47:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-11","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6819,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.59506,"AVALU":"mg/L","BASE2":11.27599,"BASE":8.59506,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.68093,"PCHG2":-23.77554,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-15 15:47:06","ADY":250,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-237","SUBJID":"id-237","SITEID":"BRA-11","AGE":64,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.29531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-03-10","TRTSDTM":"2020-03-10 15:47:06","TRTEDTM":"2023-03-11 09:47:06","TRT01SDTM":"2020-03-10 15:47:06","TRT01EDTM":"2022-03-11 03:47:06","TRT02SDTM":"2022-03-11 03:47:06","TRT02EDTM":"2023-03-11 09:47:06","AP01SDTM":"2020-03-10 15:47:06","AP01EDTM":"2022-03-11 03:47:06","AP02SDTM":"2022-03-11 03:47:06","AP02EDTM":"2023-03-11 09:47:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-11","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3361,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.88031,"AVALU":"mg/L","BASE2":11.27599,"BASE":8.59506,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.39568,"PCHG2":-21.24586,"CHG":0.28525,"PCHG":3.31873,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-03 15:47:06","ADY":419,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-237","SUBJID":"id-237","SITEID":"BRA-11","AGE":64,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.29531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-03-10","TRTSDTM":"2020-03-10 15:47:06","TRTEDTM":"2023-03-11 09:47:06","TRT01SDTM":"2020-03-10 15:47:06","TRT01EDTM":"2022-03-11 03:47:06","TRT02SDTM":"2022-03-11 03:47:06","TRT02EDTM":"2023-03-11 09:47:06","AP01SDTM":"2020-03-10 15:47:06","AP01EDTM":"2022-03-11 03:47:06","AP02SDTM":"2022-03-11 03:47:06","AP02EDTM":"2023-03-11 09:47:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-11","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5306,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.55596,"AVALU":"mg/L","BASE2":11.27599,"BASE":8.59506,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.72002,"PCHG2":-24.12228,"CHG":-0.0391,"PCHG":-0.45489,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-01 15:47:06","ADY":693,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-237","SUBJID":"id-237","SITEID":"BRA-11","AGE":64,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.29531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-03-10","TRTSDTM":"2020-03-10 15:47:06","TRTEDTM":"2023-03-11 09:47:06","TRT01SDTM":"2020-03-10 15:47:06","TRT01EDTM":"2022-03-11 03:47:06","TRT02SDTM":"2022-03-11 03:47:06","TRT02EDTM":"2023-03-11 09:47:06","AP01SDTM":"2020-03-10 15:47:06","AP01EDTM":"2022-03-11 03:47:06","AP02SDTM":"2022-03-11 03:47:06","AP02EDTM":"2023-03-11 09:47:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-11","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":203,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.83277,"AVALU":"mg/L","BASE2":11.27599,"BASE":8.59506,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.44322,"PCHG2":-21.66745,"CHG":0.23771,"PCHG":2.76564,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-17 15:47:06","ADY":859,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-237","SUBJID":"id-237","SITEID":"BRA-11","AGE":64,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.29531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-03-10","TRTSDTM":"2020-03-10 15:47:06","TRTEDTM":"2023-03-11 09:47:06","TRT01SDTM":"2020-03-10 15:47:06","TRT01EDTM":"2022-03-11 03:47:06","TRT02SDTM":"2022-03-11 03:47:06","TRT02EDTM":"2023-03-11 09:47:06","AP01SDTM":"2020-03-10 15:47:06","AP01EDTM":"2022-03-11 03:47:06","AP02SDTM":"2022-03-11 03:47:06","AP02EDTM":"2023-03-11 09:47:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-11","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1842,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.84235,"AVALU":"mg/L","BASE2":11.27599,"BASE":8.59506,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.43364,"PCHG2":-21.58246,"CHG":0.24729,"PCHG":2.87713,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-23 15:47:06","ADY":896,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-237","SUBJID":"id-237","SITEID":"BRA-11","AGE":64,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.29531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-03-10","TRTSDTM":"2020-03-10 15:47:06","TRTEDTM":"2023-03-11 09:47:06","TRT01SDTM":"2020-03-10 15:47:06","TRT01EDTM":"2022-03-11 03:47:06","TRT02SDTM":"2022-03-11 03:47:06","TRT02EDTM":"2023-03-11 09:47:06","AP01SDTM":"2020-03-10 15:47:06","AP01EDTM":"2022-03-11 03:47:06","AP02SDTM":"2022-03-11 03:47:06","AP02EDTM":"2023-03-11 09:47:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-11","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3310,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.48505,"AVALU":"mg/L","BASE2":11.27599,"BASE":8.59506,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.79093,"PCHG2":-15.88271,"CHG":0.88999,"PCHG":10.35473,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-15 15:47:06","ADY":1041,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-237","SUBJID":"id-237","SITEID":"BRA-11","AGE":64,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.29531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-03-10","TRTSDTM":"2020-03-10 15:47:06","TRTEDTM":"2023-03-11 09:47:06","TRT01SDTM":"2020-03-10 15:47:06","TRT01EDTM":"2022-03-11 03:47:06","TRT02SDTM":"2022-03-11 03:47:06","TRT02EDTM":"2023-03-11 09:47:06","AP01SDTM":"2020-03-10 15:47:06","AP01EDTM":"2022-03-11 03:47:06","AP02SDTM":"2022-03-11 03:47:06","AP02EDTM":"2023-03-11 09:47:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-11","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1181,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87604,"AVALU":"g/L","BASE2":2.87604,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-23 15:47:06","ADY":74,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-237","SUBJID":"id-237","SITEID":"BRA-11","AGE":64,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.29531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-03-10","TRTSDTM":"2020-03-10 15:47:06","TRTEDTM":"2023-03-11 09:47:06","TRT01SDTM":"2020-03-10 15:47:06","TRT01EDTM":"2022-03-11 03:47:06","TRT02SDTM":"2022-03-11 03:47:06","TRT02EDTM":"2023-03-11 09:47:06","AP01SDTM":"2020-03-10 15:47:06","AP01EDTM":"2022-03-11 03:47:06","AP02SDTM":"2022-03-11 03:47:06","AP02EDTM":"2023-03-11 09:47:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-11","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7628,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94231,"AVALU":"g/L","BASE2":2.87604,"BASE":2.94231,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.06627,"PCHG2":2.30408,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-15 15:47:06","ADY":250,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-237","SUBJID":"id-237","SITEID":"BRA-11","AGE":64,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.29531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-03-10","TRTSDTM":"2020-03-10 15:47:06","TRTEDTM":"2023-03-11 09:47:06","TRT01SDTM":"2020-03-10 15:47:06","TRT01EDTM":"2022-03-11 03:47:06","TRT02SDTM":"2022-03-11 03:47:06","TRT02EDTM":"2023-03-11 09:47:06","AP01SDTM":"2020-03-10 15:47:06","AP01EDTM":"2022-03-11 03:47:06","AP02SDTM":"2022-03-11 03:47:06","AP02EDTM":"2023-03-11 09:47:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-11","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7636,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96192,"AVALU":"g/L","BASE2":2.87604,"BASE":2.94231,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08587,"PCHG2":2.98587,"CHG":0.01961,"PCHG":0.66643,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-03 15:47:06","ADY":419,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-237","SUBJID":"id-237","SITEID":"BRA-11","AGE":64,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.29531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-03-10","TRTSDTM":"2020-03-10 15:47:06","TRTEDTM":"2023-03-11 09:47:06","TRT01SDTM":"2020-03-10 15:47:06","TRT01EDTM":"2022-03-11 03:47:06","TRT02SDTM":"2022-03-11 03:47:06","TRT02EDTM":"2023-03-11 09:47:06","AP01SDTM":"2020-03-10 15:47:06","AP01EDTM":"2022-03-11 03:47:06","AP02SDTM":"2022-03-11 03:47:06","AP02EDTM":"2023-03-11 09:47:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-11","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8089,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7914,"AVALU":"g/L","BASE2":2.87604,"BASE":2.94231,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08464,"PCHG2":-2.94295,"CHG":-0.15091,"PCHG":-5.12887,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-01 15:47:06","ADY":693,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-237","SUBJID":"id-237","SITEID":"BRA-11","AGE":64,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.29531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-03-10","TRTSDTM":"2020-03-10 15:47:06","TRTEDTM":"2023-03-11 09:47:06","TRT01SDTM":"2020-03-10 15:47:06","TRT01EDTM":"2022-03-11 03:47:06","TRT02SDTM":"2022-03-11 03:47:06","TRT02EDTM":"2023-03-11 09:47:06","AP01SDTM":"2020-03-10 15:47:06","AP01EDTM":"2022-03-11 03:47:06","AP02SDTM":"2022-03-11 03:47:06","AP02EDTM":"2023-03-11 09:47:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-11","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2239,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93273,"AVALU":"g/L","BASE2":2.87604,"BASE":2.94231,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05668,"PCHG2":1.97088,"CHG":-0.00958,"PCHG":-0.3257,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-17 15:47:06","ADY":859,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-237","SUBJID":"id-237","SITEID":"BRA-11","AGE":64,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.29531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-03-10","TRTSDTM":"2020-03-10 15:47:06","TRTEDTM":"2023-03-11 09:47:06","TRT01SDTM":"2020-03-10 15:47:06","TRT01EDTM":"2022-03-11 03:47:06","TRT02SDTM":"2022-03-11 03:47:06","TRT02EDTM":"2023-03-11 09:47:06","AP01SDTM":"2020-03-10 15:47:06","AP01EDTM":"2022-03-11 03:47:06","AP02SDTM":"2022-03-11 03:47:06","AP02EDTM":"2023-03-11 09:47:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-11","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4635,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85508,"AVALU":"g/L","BASE2":2.87604,"BASE":2.94231,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02096,"PCHG2":-0.72887,"CHG":-0.08723,"PCHG":-2.96465,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-23 15:47:06","ADY":896,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-237","SUBJID":"id-237","SITEID":"BRA-11","AGE":64,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.29531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-03-10","TRTSDTM":"2020-03-10 15:47:06","TRTEDTM":"2023-03-11 09:47:06","TRT01SDTM":"2020-03-10 15:47:06","TRT01EDTM":"2022-03-11 03:47:06","TRT02SDTM":"2022-03-11 03:47:06","TRT02EDTM":"2023-03-11 09:47:06","AP01SDTM":"2020-03-10 15:47:06","AP01EDTM":"2022-03-11 03:47:06","AP02SDTM":"2022-03-11 03:47:06","AP02EDTM":"2023-03-11 09:47:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-11","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7707,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88381,"AVALU":"g/L","BASE2":2.87604,"BASE":2.94231,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00776,"PCHG2":0.26992,"CHG":-0.0585,"PCHG":-1.98835,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-15 15:47:06","ADY":1041,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-321","SUBJID":"id-321","SITEID":"BRA-11","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":1.77524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-06","TRTSDTM":"2020-10-06 11:27:51","TRTEDTM":"2023-10-07 05:27:51","TRT01SDTM":"2020-10-06 11:27:51","TRT01EDTM":"2022-10-06 23:27:51","TRT02SDTM":"2022-10-06 23:27:51","TRT02EDTM":"2023-10-07 05:27:51","AP01SDTM":"2020-10-06 11:27:51","AP01EDTM":"2022-10-06 23:27:51","AP02SDTM":"2022-10-06 23:27:51","AP02EDTM":"2023-10-07 05:27:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-07","EOSDY":1096,"LSTALVDT":"2023-10-29","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3332,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.70489,"AVALU":"U/L","BASE2":19.70489,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-11 11:27:51","ADY":187,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-321","SUBJID":"id-321","SITEID":"BRA-11","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":1.77524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-06","TRTSDTM":"2020-10-06 11:27:51","TRTEDTM":"2023-10-07 05:27:51","TRT01SDTM":"2020-10-06 11:27:51","TRT01EDTM":"2022-10-06 23:27:51","TRT02SDTM":"2022-10-06 23:27:51","TRT02EDTM":"2023-10-07 05:27:51","AP01SDTM":"2020-10-06 11:27:51","AP01EDTM":"2022-10-06 23:27:51","AP02SDTM":"2022-10-06 23:27:51","AP02EDTM":"2023-10-07 05:27:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-07","EOSDY":1096,"LSTALVDT":"2023-10-29","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":445,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.61306,"AVALU":"U/L","BASE2":19.70489,"BASE":15.61306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-4.09184,"PCHG2":-20.76558,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-25 11:27:51","ADY":231,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-321","SUBJID":"id-321","SITEID":"BRA-11","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":1.77524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-06","TRTSDTM":"2020-10-06 11:27:51","TRTEDTM":"2023-10-07 05:27:51","TRT01SDTM":"2020-10-06 11:27:51","TRT01EDTM":"2022-10-06 23:27:51","TRT02SDTM":"2022-10-06 23:27:51","TRT02EDTM":"2023-10-07 05:27:51","AP01SDTM":"2020-10-06 11:27:51","AP01EDTM":"2022-10-06 23:27:51","AP02SDTM":"2022-10-06 23:27:51","AP02EDTM":"2023-10-07 05:27:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-07","EOSDY":1096,"LSTALVDT":"2023-10-29","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4381,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.31638,"AVALU":"U/L","BASE2":19.70489,"BASE":15.61306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.61149,"PCHG2":33.5525,"CHG":10.70332,"PCHG":68.55364,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-25 11:27:51","ADY":262,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-321","SUBJID":"id-321","SITEID":"BRA-11","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":1.77524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-06","TRTSDTM":"2020-10-06 11:27:51","TRTEDTM":"2023-10-07 05:27:51","TRT01SDTM":"2020-10-06 11:27:51","TRT01EDTM":"2022-10-06 23:27:51","TRT02SDTM":"2022-10-06 23:27:51","TRT02EDTM":"2023-10-07 05:27:51","AP01SDTM":"2020-10-06 11:27:51","AP01EDTM":"2022-10-06 23:27:51","AP02SDTM":"2022-10-06 23:27:51","AP02EDTM":"2023-10-07 05:27:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-07","EOSDY":1096,"LSTALVDT":"2023-10-29","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5474,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.22783,"AVALU":"U/L","BASE2":19.70489,"BASE":15.61306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.47706,"PCHG2":-58.24473,"CHG":-7.38523,"PCHG":-47.30161,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-11 11:27:51","ADY":431,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-321","SUBJID":"id-321","SITEID":"BRA-11","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":1.77524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-06","TRTSDTM":"2020-10-06 11:27:51","TRTEDTM":"2023-10-07 05:27:51","TRT01SDTM":"2020-10-06 11:27:51","TRT01EDTM":"2022-10-06 23:27:51","TRT02SDTM":"2022-10-06 23:27:51","TRT02EDTM":"2023-10-07 05:27:51","AP01SDTM":"2020-10-06 11:27:51","AP01EDTM":"2022-10-06 23:27:51","AP02SDTM":"2022-10-06 23:27:51","AP02EDTM":"2023-10-07 05:27:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-07","EOSDY":1096,"LSTALVDT":"2023-10-29","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":58,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.28962,"AVALU":"U/L","BASE2":19.70489,"BASE":15.61306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.41527,"PCHG2":-32.55675,"CHG":-2.32344,"PCHG":-14.88137,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-19 11:27:51","ADY":682,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-321","SUBJID":"id-321","SITEID":"BRA-11","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":1.77524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-06","TRTSDTM":"2020-10-06 11:27:51","TRTEDTM":"2023-10-07 05:27:51","TRT01SDTM":"2020-10-06 11:27:51","TRT01EDTM":"2022-10-06 23:27:51","TRT02SDTM":"2022-10-06 23:27:51","TRT02EDTM":"2023-10-07 05:27:51","AP01SDTM":"2020-10-06 11:27:51","AP01EDTM":"2022-10-06 23:27:51","AP02SDTM":"2022-10-06 23:27:51","AP02EDTM":"2023-10-07 05:27:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-07","EOSDY":1096,"LSTALVDT":"2023-10-29","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4747,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.24971,"AVALU":"U/L","BASE2":19.70489,"BASE":15.61306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-19.45519,"PCHG2":-98.73275,"CHG":-15.36335,"PCHG":-98.40064,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2023-03-22 11:27:51","ADY":897,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-321","SUBJID":"id-321","SITEID":"BRA-11","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":1.77524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-06","TRTSDTM":"2020-10-06 11:27:51","TRTEDTM":"2023-10-07 05:27:51","TRT01SDTM":"2020-10-06 11:27:51","TRT01EDTM":"2022-10-06 23:27:51","TRT02SDTM":"2022-10-06 23:27:51","TRT02EDTM":"2023-10-07 05:27:51","AP01SDTM":"2020-10-06 11:27:51","AP01EDTM":"2022-10-06 23:27:51","AP02SDTM":"2022-10-06 23:27:51","AP02EDTM":"2023-10-07 05:27:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-07","EOSDY":1096,"LSTALVDT":"2023-10-29","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3595,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.77531,"AVALU":"U/L","BASE2":19.70489,"BASE":15.61306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.92959,"PCHG2":-30.09195,"CHG":-1.83775,"PCHG":-11.77061,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-05 11:27:51","ADY":972,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-321","SUBJID":"id-321","SITEID":"BRA-11","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":1.77524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-06","TRTSDTM":"2020-10-06 11:27:51","TRTEDTM":"2023-10-07 05:27:51","TRT01SDTM":"2020-10-06 11:27:51","TRT01EDTM":"2022-10-06 23:27:51","TRT02SDTM":"2022-10-06 23:27:51","TRT02EDTM":"2023-10-07 05:27:51","AP01SDTM":"2020-10-06 11:27:51","AP01EDTM":"2022-10-06 23:27:51","AP02SDTM":"2022-10-06 23:27:51","AP02EDTM":"2023-10-07 05:27:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-07","EOSDY":1096,"LSTALVDT":"2023-10-29","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":281,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.31832,"AVALU":"mg/L","BASE2":9.31832,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-11 11:27:51","ADY":187,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-321","SUBJID":"id-321","SITEID":"BRA-11","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":1.77524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-06","TRTSDTM":"2020-10-06 11:27:51","TRTEDTM":"2023-10-07 05:27:51","TRT01SDTM":"2020-10-06 11:27:51","TRT01EDTM":"2022-10-06 23:27:51","TRT02SDTM":"2022-10-06 23:27:51","TRT02EDTM":"2023-10-07 05:27:51","AP01SDTM":"2020-10-06 11:27:51","AP01EDTM":"2022-10-06 23:27:51","AP02SDTM":"2022-10-06 23:27:51","AP02EDTM":"2023-10-07 05:27:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-07","EOSDY":1096,"LSTALVDT":"2023-10-29","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6013,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.18692,"AVALU":"mg/L","BASE2":9.31832,"BASE":8.18692,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.1314,"PCHG2":-12.14172,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-25 11:27:51","ADY":231,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-321","SUBJID":"id-321","SITEID":"BRA-11","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":1.77524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-06","TRTSDTM":"2020-10-06 11:27:51","TRTEDTM":"2023-10-07 05:27:51","TRT01SDTM":"2020-10-06 11:27:51","TRT01EDTM":"2022-10-06 23:27:51","TRT02SDTM":"2022-10-06 23:27:51","TRT02EDTM":"2023-10-07 05:27:51","AP01SDTM":"2020-10-06 11:27:51","AP01EDTM":"2022-10-06 23:27:51","AP02SDTM":"2022-10-06 23:27:51","AP02EDTM":"2023-10-07 05:27:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-07","EOSDY":1096,"LSTALVDT":"2023-10-29","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1865,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.62708,"AVALU":"mg/L","BASE2":9.31832,"BASE":8.18692,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.69124,"PCHG2":-7.41811,"CHG":0.44016,"PCHG":5.37639,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-25 11:27:51","ADY":262,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-321","SUBJID":"id-321","SITEID":"BRA-11","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":1.77524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-06","TRTSDTM":"2020-10-06 11:27:51","TRTEDTM":"2023-10-07 05:27:51","TRT01SDTM":"2020-10-06 11:27:51","TRT01EDTM":"2022-10-06 23:27:51","TRT02SDTM":"2022-10-06 23:27:51","TRT02EDTM":"2023-10-07 05:27:51","AP01SDTM":"2020-10-06 11:27:51","AP01EDTM":"2022-10-06 23:27:51","AP02SDTM":"2022-10-06 23:27:51","AP02EDTM":"2023-10-07 05:27:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-07","EOSDY":1096,"LSTALVDT":"2023-10-29","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7273,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.6707,"AVALU":"mg/L","BASE2":9.31832,"BASE":8.18692,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.64763,"PCHG2":-6.95003,"CHG":0.48378,"PCHG":5.90916,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-11 11:27:51","ADY":431,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-321","SUBJID":"id-321","SITEID":"BRA-11","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":1.77524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-06","TRTSDTM":"2020-10-06 11:27:51","TRTEDTM":"2023-10-07 05:27:51","TRT01SDTM":"2020-10-06 11:27:51","TRT01EDTM":"2022-10-06 23:27:51","TRT02SDTM":"2022-10-06 23:27:51","TRT02EDTM":"2023-10-07 05:27:51","AP01SDTM":"2020-10-06 11:27:51","AP01EDTM":"2022-10-06 23:27:51","AP02SDTM":"2022-10-06 23:27:51","AP02EDTM":"2023-10-07 05:27:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-07","EOSDY":1096,"LSTALVDT":"2023-10-29","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":696,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.10219,"AVALU":"mg/L","BASE2":9.31832,"BASE":8.18692,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.21614,"PCHG2":-13.05101,"CHG":-0.08473,"PCHG":-1.03496,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-19 11:27:51","ADY":682,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-321","SUBJID":"id-321","SITEID":"BRA-11","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":1.77524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-06","TRTSDTM":"2020-10-06 11:27:51","TRTEDTM":"2023-10-07 05:27:51","TRT01SDTM":"2020-10-06 11:27:51","TRT01EDTM":"2022-10-06 23:27:51","TRT02SDTM":"2022-10-06 23:27:51","TRT02EDTM":"2023-10-07 05:27:51","AP01SDTM":"2020-10-06 11:27:51","AP01EDTM":"2022-10-06 23:27:51","AP02SDTM":"2022-10-06 23:27:51","AP02EDTM":"2023-10-07 05:27:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-07","EOSDY":1096,"LSTALVDT":"2023-10-29","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":177,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.41162,"AVALU":"mg/L","BASE2":9.31832,"BASE":8.18692,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0933,"PCHG2":1.00127,"CHG":1.22471,"PCHG":14.9593,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-22 11:27:51","ADY":897,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-321","SUBJID":"id-321","SITEID":"BRA-11","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":1.77524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-06","TRTSDTM":"2020-10-06 11:27:51","TRTEDTM":"2023-10-07 05:27:51","TRT01SDTM":"2020-10-06 11:27:51","TRT01EDTM":"2022-10-06 23:27:51","TRT02SDTM":"2022-10-06 23:27:51","TRT02EDTM":"2023-10-07 05:27:51","AP01SDTM":"2020-10-06 11:27:51","AP01EDTM":"2022-10-06 23:27:51","AP02SDTM":"2022-10-06 23:27:51","AP02EDTM":"2023-10-07 05:27:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-07","EOSDY":1096,"LSTALVDT":"2023-10-29","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5084,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.50107,"AVALU":"mg/L","BASE2":9.31832,"BASE":8.18692,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18275,"PCHG2":1.96118,"CHG":1.31415,"PCHG":16.05187,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-05 11:27:51","ADY":972,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-321","SUBJID":"id-321","SITEID":"BRA-11","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":1.77524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-06","TRTSDTM":"2020-10-06 11:27:51","TRTEDTM":"2023-10-07 05:27:51","TRT01SDTM":"2020-10-06 11:27:51","TRT01EDTM":"2022-10-06 23:27:51","TRT02SDTM":"2022-10-06 23:27:51","TRT02EDTM":"2023-10-07 05:27:51","AP01SDTM":"2020-10-06 11:27:51","AP01EDTM":"2022-10-06 23:27:51","AP02SDTM":"2022-10-06 23:27:51","AP02EDTM":"2023-10-07 05:27:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-07","EOSDY":1096,"LSTALVDT":"2023-10-29","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5355,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05391,"AVALU":"g/L","BASE2":3.05391,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"4","BTOXGR":"0","ADTM":"2021-04-11 11:27:51","ADY":187,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-321","SUBJID":"id-321","SITEID":"BRA-11","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":1.77524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-06","TRTSDTM":"2020-10-06 11:27:51","TRTEDTM":"2023-10-07 05:27:51","TRT01SDTM":"2020-10-06 11:27:51","TRT01EDTM":"2022-10-06 23:27:51","TRT02SDTM":"2022-10-06 23:27:51","TRT02EDTM":"2023-10-07 05:27:51","AP01SDTM":"2020-10-06 11:27:51","AP01EDTM":"2022-10-06 23:27:51","AP02SDTM":"2022-10-06 23:27:51","AP02EDTM":"2023-10-07 05:27:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-07","EOSDY":1096,"LSTALVDT":"2023-10-29","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7236,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97174,"AVALU":"g/L","BASE2":3.05391,"BASE":2.97174,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.08217,"PCHG2":-2.69068,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-25 11:27:51","ADY":231,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-321","SUBJID":"id-321","SITEID":"BRA-11","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":1.77524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-06","TRTSDTM":"2020-10-06 11:27:51","TRTEDTM":"2023-10-07 05:27:51","TRT01SDTM":"2020-10-06 11:27:51","TRT01EDTM":"2022-10-06 23:27:51","TRT02SDTM":"2022-10-06 23:27:51","TRT02EDTM":"2023-10-07 05:27:51","AP01SDTM":"2020-10-06 11:27:51","AP01EDTM":"2022-10-06 23:27:51","AP02SDTM":"2022-10-06 23:27:51","AP02EDTM":"2023-10-07 05:27:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-07","EOSDY":1096,"LSTALVDT":"2023-10-29","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5843,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74431,"AVALU":"g/L","BASE2":3.05391,"BASE":2.97174,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.3096,"PCHG2":-10.13795,"CHG":-0.22743,"PCHG":-7.6532,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-25 11:27:51","ADY":262,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-321","SUBJID":"id-321","SITEID":"BRA-11","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":1.77524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-06","TRTSDTM":"2020-10-06 11:27:51","TRTEDTM":"2023-10-07 05:27:51","TRT01SDTM":"2020-10-06 11:27:51","TRT01EDTM":"2022-10-06 23:27:51","TRT02SDTM":"2022-10-06 23:27:51","TRT02EDTM":"2023-10-07 05:27:51","AP01SDTM":"2020-10-06 11:27:51","AP01EDTM":"2022-10-06 23:27:51","AP02SDTM":"2022-10-06 23:27:51","AP02EDTM":"2023-10-07 05:27:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-07","EOSDY":1096,"LSTALVDT":"2023-10-29","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7500,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89134,"AVALU":"g/L","BASE2":3.05391,"BASE":2.97174,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16257,"PCHG2":-5.32335,"CHG":-0.0804,"PCHG":-2.70546,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-11 11:27:51","ADY":431,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-321","SUBJID":"id-321","SITEID":"BRA-11","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":1.77524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-06","TRTSDTM":"2020-10-06 11:27:51","TRTEDTM":"2023-10-07 05:27:51","TRT01SDTM":"2020-10-06 11:27:51","TRT01EDTM":"2022-10-06 23:27:51","TRT02SDTM":"2022-10-06 23:27:51","TRT02EDTM":"2023-10-07 05:27:51","AP01SDTM":"2020-10-06 11:27:51","AP01EDTM":"2022-10-06 23:27:51","AP02SDTM":"2022-10-06 23:27:51","AP02EDTM":"2023-10-07 05:27:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-07","EOSDY":1096,"LSTALVDT":"2023-10-29","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4325,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87149,"AVALU":"g/L","BASE2":3.05391,"BASE":2.97174,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18243,"PCHG2":-5.97353,"CHG":-0.10026,"PCHG":-3.37362,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-19 11:27:51","ADY":682,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-321","SUBJID":"id-321","SITEID":"BRA-11","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":1.77524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-06","TRTSDTM":"2020-10-06 11:27:51","TRTEDTM":"2023-10-07 05:27:51","TRT01SDTM":"2020-10-06 11:27:51","TRT01EDTM":"2022-10-06 23:27:51","TRT02SDTM":"2022-10-06 23:27:51","TRT02EDTM":"2023-10-07 05:27:51","AP01SDTM":"2020-10-06 11:27:51","AP01EDTM":"2022-10-06 23:27:51","AP02SDTM":"2022-10-06 23:27:51","AP02EDTM":"2023-10-07 05:27:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-07","EOSDY":1096,"LSTALVDT":"2023-10-29","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6602,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96146,"AVALU":"g/L","BASE2":3.05391,"BASE":2.97174,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09245,"PCHG2":-3.02738,"CHG":-0.01028,"PCHG":-0.34601,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-22 11:27:51","ADY":897,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-321","SUBJID":"id-321","SITEID":"BRA-11","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":1.77524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-06","TRTSDTM":"2020-10-06 11:27:51","TRTEDTM":"2023-10-07 05:27:51","TRT01SDTM":"2020-10-06 11:27:51","TRT01EDTM":"2022-10-06 23:27:51","TRT02SDTM":"2022-10-06 23:27:51","TRT02EDTM":"2023-10-07 05:27:51","AP01SDTM":"2020-10-06 11:27:51","AP01EDTM":"2022-10-06 23:27:51","AP02SDTM":"2022-10-06 23:27:51","AP02EDTM":"2023-10-07 05:27:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-07","EOSDY":1096,"LSTALVDT":"2023-10-29","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7915,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97492,"AVALU":"g/L","BASE2":3.05391,"BASE":2.97174,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.079,"PCHG2":-2.58671,"CHG":0.00318,"PCHG":0.10685,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-05 11:27:51","ADY":972,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-345","SUBJID":"id-345","SITEID":"BRA-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.45154,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-15","TRTSDTM":"2020-08-18 04:51:06","TRTEDTM":"2023-08-18 22:51:06","TRT01SDTM":"2020-08-18 04:51:06","TRT01EDTM":"2022-08-18 16:51:06","TRT02SDTM":"2022-08-18 16:51:06","TRT02EDTM":"2023-08-18 22:51:06","AP01SDTM":"2020-08-18 04:51:06","AP01EDTM":"2022-08-18 16:51:06","AP02SDTM":"2022-08-18 16:51:06","AP02EDTM":"2023-08-18 22:51:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-02","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5210,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.93674,"AVALU":"U/L","BASE2":26.93674,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-30 04:51:06","ADY":134,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-345","SUBJID":"id-345","SITEID":"BRA-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.45154,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-15","TRTSDTM":"2020-08-18 04:51:06","TRTEDTM":"2023-08-18 22:51:06","TRT01SDTM":"2020-08-18 04:51:06","TRT01EDTM":"2022-08-18 16:51:06","TRT02SDTM":"2022-08-18 16:51:06","TRT02EDTM":"2023-08-18 22:51:06","AP01SDTM":"2020-08-18 04:51:06","AP01EDTM":"2022-08-18 16:51:06","AP02SDTM":"2022-08-18 16:51:06","AP02EDTM":"2023-08-18 22:51:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-02","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2542,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.50043,"AVALU":"U/L","BASE2":26.93674,"BASE":26.50043,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.4363,"PCHG2":-1.61973,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-17 04:51:06","ADY":456,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-345","SUBJID":"id-345","SITEID":"BRA-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.45154,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-15","TRTSDTM":"2020-08-18 04:51:06","TRTEDTM":"2023-08-18 22:51:06","TRT01SDTM":"2020-08-18 04:51:06","TRT01EDTM":"2022-08-18 16:51:06","TRT02SDTM":"2022-08-18 16:51:06","TRT02EDTM":"2023-08-18 22:51:06","AP01SDTM":"2020-08-18 04:51:06","AP01EDTM":"2022-08-18 16:51:06","AP02SDTM":"2022-08-18 16:51:06","AP02EDTM":"2023-08-18 22:51:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-02","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4507,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.94661,"AVALU":"U/L","BASE2":26.93674,"BASE":26.50043,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.99013,"PCHG2":-48.22458,"CHG":-12.55383,"PCHG":-47.37215,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-05 04:51:06","ADY":748,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-345","SUBJID":"id-345","SITEID":"BRA-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.45154,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-15","TRTSDTM":"2020-08-18 04:51:06","TRTEDTM":"2023-08-18 22:51:06","TRT01SDTM":"2020-08-18 04:51:06","TRT01EDTM":"2022-08-18 16:51:06","TRT02SDTM":"2022-08-18 16:51:06","TRT02EDTM":"2023-08-18 22:51:06","AP01SDTM":"2020-08-18 04:51:06","AP01EDTM":"2022-08-18 16:51:06","AP02SDTM":"2022-08-18 16:51:06","AP02EDTM":"2023-08-18 22:51:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-02","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5423,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.61897,"AVALU":"U/L","BASE2":26.93674,"BASE":26.50043,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.31776,"PCHG2":-23.45408,"CHG":-5.88146,"PCHG":-22.19383,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-27 04:51:06","ADY":770,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-345","SUBJID":"id-345","SITEID":"BRA-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.45154,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-15","TRTSDTM":"2020-08-18 04:51:06","TRTEDTM":"2023-08-18 22:51:06","TRT01SDTM":"2020-08-18 04:51:06","TRT01EDTM":"2022-08-18 16:51:06","TRT02SDTM":"2022-08-18 16:51:06","TRT02EDTM":"2023-08-18 22:51:06","AP01SDTM":"2020-08-18 04:51:06","AP01EDTM":"2022-08-18 16:51:06","AP02SDTM":"2022-08-18 16:51:06","AP02EDTM":"2023-08-18 22:51:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-02","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8181,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.83083,"AVALU":"U/L","BASE2":26.93674,"BASE":26.50043,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1059,"PCHG2":-0.39316,"CHG":0.3304,"PCHG":1.24677,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-21 04:51:06","ADY":855,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-345","SUBJID":"id-345","SITEID":"BRA-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.45154,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-15","TRTSDTM":"2020-08-18 04:51:06","TRTEDTM":"2023-08-18 22:51:06","TRT01SDTM":"2020-08-18 04:51:06","TRT01EDTM":"2022-08-18 16:51:06","TRT02SDTM":"2022-08-18 16:51:06","TRT02EDTM":"2023-08-18 22:51:06","AP01SDTM":"2020-08-18 04:51:06","AP01EDTM":"2022-08-18 16:51:06","AP02SDTM":"2022-08-18 16:51:06","AP02EDTM":"2023-08-18 22:51:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-02","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1666,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.61587,"AVALU":"U/L","BASE2":26.93674,"BASE":26.50043,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.32087,"PCHG2":-30.8904,"CHG":-7.88456,"PCHG":-29.75258,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-17 04:51:06","ADY":882,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-345","SUBJID":"id-345","SITEID":"BRA-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.45154,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-15","TRTSDTM":"2020-08-18 04:51:06","TRTEDTM":"2023-08-18 22:51:06","TRT01SDTM":"2020-08-18 04:51:06","TRT01EDTM":"2022-08-18 16:51:06","TRT02SDTM":"2022-08-18 16:51:06","TRT02EDTM":"2023-08-18 22:51:06","AP01SDTM":"2020-08-18 04:51:06","AP01EDTM":"2022-08-18 16:51:06","AP02SDTM":"2022-08-18 16:51:06","AP02EDTM":"2023-08-18 22:51:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-02","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5288,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.05197,"AVALU":"U/L","BASE2":26.93674,"BASE":26.50043,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.88477,"PCHG2":-62.68306,"CHG":-16.44847,"PCHG":-62.06868,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-30 04:51:06","ADY":954,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-345","SUBJID":"id-345","SITEID":"BRA-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.45154,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-15","TRTSDTM":"2020-08-18 04:51:06","TRTEDTM":"2023-08-18 22:51:06","TRT01SDTM":"2020-08-18 04:51:06","TRT01EDTM":"2022-08-18 16:51:06","TRT02SDTM":"2022-08-18 16:51:06","TRT02EDTM":"2023-08-18 22:51:06","AP01SDTM":"2020-08-18 04:51:06","AP01EDTM":"2022-08-18 16:51:06","AP02SDTM":"2022-08-18 16:51:06","AP02EDTM":"2023-08-18 22:51:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-02","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3625,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.15394,"AVALU":"mg/L","BASE2":10.15394,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-12-30 04:51:06","ADY":134,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-345","SUBJID":"id-345","SITEID":"BRA-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.45154,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-15","TRTSDTM":"2020-08-18 04:51:06","TRTEDTM":"2023-08-18 22:51:06","TRT01SDTM":"2020-08-18 04:51:06","TRT01EDTM":"2022-08-18 16:51:06","TRT02SDTM":"2022-08-18 16:51:06","TRT02EDTM":"2023-08-18 22:51:06","AP01SDTM":"2020-08-18 04:51:06","AP01EDTM":"2022-08-18 16:51:06","AP02SDTM":"2022-08-18 16:51:06","AP02EDTM":"2023-08-18 22:51:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-02","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1707,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.652,"AVALU":"mg/L","BASE2":10.15394,"BASE":8.652,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.50194,"PCHG2":-14.79171,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-17 04:51:06","ADY":456,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-345","SUBJID":"id-345","SITEID":"BRA-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.45154,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-15","TRTSDTM":"2020-08-18 04:51:06","TRTEDTM":"2023-08-18 22:51:06","TRT01SDTM":"2020-08-18 04:51:06","TRT01EDTM":"2022-08-18 16:51:06","TRT02SDTM":"2022-08-18 16:51:06","TRT02EDTM":"2023-08-18 22:51:06","AP01SDTM":"2020-08-18 04:51:06","AP01EDTM":"2022-08-18 16:51:06","AP02SDTM":"2022-08-18 16:51:06","AP02EDTM":"2023-08-18 22:51:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-02","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4951,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.60319,"AVALU":"mg/L","BASE2":10.15394,"BASE":8.652,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.55076,"PCHG2":-15.27247,"CHG":-0.04882,"PCHG":-0.56422,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-05 04:51:06","ADY":748,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-345","SUBJID":"id-345","SITEID":"BRA-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.45154,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-15","TRTSDTM":"2020-08-18 04:51:06","TRTEDTM":"2023-08-18 22:51:06","TRT01SDTM":"2020-08-18 04:51:06","TRT01EDTM":"2022-08-18 16:51:06","TRT02SDTM":"2022-08-18 16:51:06","TRT02EDTM":"2023-08-18 22:51:06","AP01SDTM":"2020-08-18 04:51:06","AP01EDTM":"2022-08-18 16:51:06","AP02SDTM":"2022-08-18 16:51:06","AP02EDTM":"2023-08-18 22:51:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-02","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3759,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.971,"AVALU":"mg/L","BASE2":10.15394,"BASE":8.652,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.18295,"PCHG2":-21.4985,"CHG":-0.681,"PCHG":-7.87105,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-09-27 04:51:06","ADY":770,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-345","SUBJID":"id-345","SITEID":"BRA-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.45154,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-15","TRTSDTM":"2020-08-18 04:51:06","TRTEDTM":"2023-08-18 22:51:06","TRT01SDTM":"2020-08-18 04:51:06","TRT01EDTM":"2022-08-18 16:51:06","TRT02SDTM":"2022-08-18 16:51:06","TRT02EDTM":"2023-08-18 22:51:06","AP01SDTM":"2020-08-18 04:51:06","AP01EDTM":"2022-08-18 16:51:06","AP02SDTM":"2022-08-18 16:51:06","AP02EDTM":"2023-08-18 22:51:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-02","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7990,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.64898,"AVALU":"mg/L","BASE2":10.15394,"BASE":8.652,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.50497,"PCHG2":-24.66989,"CHG":-1.00303,"PCHG":-11.59298,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2022-12-21 04:51:06","ADY":855,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-345","SUBJID":"id-345","SITEID":"BRA-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.45154,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-15","TRTSDTM":"2020-08-18 04:51:06","TRTEDTM":"2023-08-18 22:51:06","TRT01SDTM":"2020-08-18 04:51:06","TRT01EDTM":"2022-08-18 16:51:06","TRT02SDTM":"2022-08-18 16:51:06","TRT02EDTM":"2023-08-18 22:51:06","AP01SDTM":"2020-08-18 04:51:06","AP01EDTM":"2022-08-18 16:51:06","AP02SDTM":"2022-08-18 16:51:06","AP02EDTM":"2023-08-18 22:51:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-02","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5964,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.88982,"AVALU":"mg/L","BASE2":10.15394,"BASE":8.652,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.26412,"PCHG2":-22.29793,"CHG":-0.76218,"PCHG":-8.80926,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2023-01-17 04:51:06","ADY":882,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-345","SUBJID":"id-345","SITEID":"BRA-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.45154,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-15","TRTSDTM":"2020-08-18 04:51:06","TRTEDTM":"2023-08-18 22:51:06","TRT01SDTM":"2020-08-18 04:51:06","TRT01EDTM":"2022-08-18 16:51:06","TRT02SDTM":"2022-08-18 16:51:06","TRT02EDTM":"2023-08-18 22:51:06","AP01SDTM":"2020-08-18 04:51:06","AP01EDTM":"2022-08-18 16:51:06","AP02SDTM":"2022-08-18 16:51:06","AP02EDTM":"2023-08-18 22:51:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-02","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6563,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.62539,"AVALU":"mg/L","BASE2":10.15394,"BASE":8.652,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.47144,"PCHG2":4.64294,"CHG":1.97338,"PCHG":22.80841,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2023-03-30 04:51:06","ADY":954,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-345","SUBJID":"id-345","SITEID":"BRA-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.45154,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-15","TRTSDTM":"2020-08-18 04:51:06","TRTEDTM":"2023-08-18 22:51:06","TRT01SDTM":"2020-08-18 04:51:06","TRT01EDTM":"2022-08-18 16:51:06","TRT02SDTM":"2022-08-18 16:51:06","TRT02EDTM":"2023-08-18 22:51:06","AP01SDTM":"2020-08-18 04:51:06","AP01EDTM":"2022-08-18 16:51:06","AP02SDTM":"2022-08-18 16:51:06","AP02EDTM":"2023-08-18 22:51:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-02","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6646,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.033,"AVALU":"g/L","BASE2":3.033,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-12-30 04:51:06","ADY":134,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-345","SUBJID":"id-345","SITEID":"BRA-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.45154,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-15","TRTSDTM":"2020-08-18 04:51:06","TRTEDTM":"2023-08-18 22:51:06","TRT01SDTM":"2020-08-18 04:51:06","TRT01EDTM":"2022-08-18 16:51:06","TRT02SDTM":"2022-08-18 16:51:06","TRT02EDTM":"2023-08-18 22:51:06","AP01SDTM":"2020-08-18 04:51:06","AP01EDTM":"2022-08-18 16:51:06","AP02SDTM":"2022-08-18 16:51:06","AP02EDTM":"2023-08-18 22:51:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-02","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6083,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86588,"AVALU":"g/L","BASE2":3.033,"BASE":2.86588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.16712,"PCHG2":-5.51002,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-17 04:51:06","ADY":456,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-345","SUBJID":"id-345","SITEID":"BRA-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.45154,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-15","TRTSDTM":"2020-08-18 04:51:06","TRTEDTM":"2023-08-18 22:51:06","TRT01SDTM":"2020-08-18 04:51:06","TRT01EDTM":"2022-08-18 16:51:06","TRT02SDTM":"2022-08-18 16:51:06","TRT02EDTM":"2023-08-18 22:51:06","AP01SDTM":"2020-08-18 04:51:06","AP01EDTM":"2022-08-18 16:51:06","AP02SDTM":"2022-08-18 16:51:06","AP02EDTM":"2023-08-18 22:51:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-02","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5595,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86276,"AVALU":"g/L","BASE2":3.033,"BASE":2.86588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17024,"PCHG2":-5.61294,"CHG":-0.00312,"PCHG":-0.10892,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-05 04:51:06","ADY":748,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-345","SUBJID":"id-345","SITEID":"BRA-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.45154,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-15","TRTSDTM":"2020-08-18 04:51:06","TRTEDTM":"2023-08-18 22:51:06","TRT01SDTM":"2020-08-18 04:51:06","TRT01EDTM":"2022-08-18 16:51:06","TRT02SDTM":"2022-08-18 16:51:06","TRT02EDTM":"2023-08-18 22:51:06","AP01SDTM":"2020-08-18 04:51:06","AP01EDTM":"2022-08-18 16:51:06","AP02SDTM":"2022-08-18 16:51:06","AP02EDTM":"2023-08-18 22:51:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-02","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3469,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84317,"AVALU":"g/L","BASE2":3.033,"BASE":2.86588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18983,"PCHG2":-6.25871,"CHG":-0.02271,"PCHG":-0.79234,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-27 04:51:06","ADY":770,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-345","SUBJID":"id-345","SITEID":"BRA-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.45154,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-15","TRTSDTM":"2020-08-18 04:51:06","TRTEDTM":"2023-08-18 22:51:06","TRT01SDTM":"2020-08-18 04:51:06","TRT01EDTM":"2022-08-18 16:51:06","TRT02SDTM":"2022-08-18 16:51:06","TRT02EDTM":"2023-08-18 22:51:06","AP01SDTM":"2020-08-18 04:51:06","AP01EDTM":"2022-08-18 16:51:06","AP02SDTM":"2022-08-18 16:51:06","AP02EDTM":"2023-08-18 22:51:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-02","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4207,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76228,"AVALU":"g/L","BASE2":3.033,"BASE":2.86588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.27072,"PCHG2":-8.92587,"CHG":-0.1036,"PCHG":-3.61504,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-21 04:51:06","ADY":855,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-345","SUBJID":"id-345","SITEID":"BRA-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.45154,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-15","TRTSDTM":"2020-08-18 04:51:06","TRTEDTM":"2023-08-18 22:51:06","TRT01SDTM":"2020-08-18 04:51:06","TRT01EDTM":"2022-08-18 16:51:06","TRT02SDTM":"2022-08-18 16:51:06","TRT02EDTM":"2023-08-18 22:51:06","AP01SDTM":"2020-08-18 04:51:06","AP01EDTM":"2022-08-18 16:51:06","AP02SDTM":"2022-08-18 16:51:06","AP02EDTM":"2023-08-18 22:51:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-02","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6863,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96287,"AVALU":"g/L","BASE2":3.033,"BASE":2.86588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07013,"PCHG2":-2.31217,"CHG":0.09699,"PCHG":3.38433,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-17 04:51:06","ADY":882,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-345","SUBJID":"id-345","SITEID":"BRA-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.45154,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-15","TRTSDTM":"2020-08-18 04:51:06","TRTEDTM":"2023-08-18 22:51:06","TRT01SDTM":"2020-08-18 04:51:06","TRT01EDTM":"2022-08-18 16:51:06","TRT02SDTM":"2022-08-18 16:51:06","TRT02EDTM":"2023-08-18 22:51:06","AP01SDTM":"2020-08-18 04:51:06","AP01EDTM":"2022-08-18 16:51:06","AP02SDTM":"2022-08-18 16:51:06","AP02EDTM":"2023-08-18 22:51:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-02","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8264,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91434,"AVALU":"g/L","BASE2":3.033,"BASE":2.86588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11866,"PCHG2":-3.91231,"CHG":0.04846,"PCHG":1.69088,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-30 04:51:06","ADY":954,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-397","SUBJID":"id-397","SITEID":"BRA-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":11.66389,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-23","TRTSDTM":"2020-06-27 21:54:37","TRTEDTM":"2023-06-28 15:54:37","TRT01SDTM":"2020-06-27 21:54:37","TRT01EDTM":"2022-06-28 09:54:37","TRT02SDTM":"2022-06-28 09:54:37","TRT02EDTM":"2023-06-28 15:54:37","AP01SDTM":"2020-06-27 21:54:37","AP01EDTM":"2022-06-28 09:54:37","AP02SDTM":"2022-06-28 09:54:37","AP02EDTM":"2023-06-28 15:54:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-10","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2194,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.48143,"AVALU":"U/L","BASE2":9.48143,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-05-04 21:54:37","ADY":311,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-397","SUBJID":"id-397","SITEID":"BRA-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":11.66389,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-23","TRTSDTM":"2020-06-27 21:54:37","TRTEDTM":"2023-06-28 15:54:37","TRT01SDTM":"2020-06-27 21:54:37","TRT01EDTM":"2022-06-28 09:54:37","TRT02SDTM":"2022-06-28 09:54:37","TRT02EDTM":"2023-06-28 15:54:37","AP01SDTM":"2020-06-27 21:54:37","AP01EDTM":"2022-06-28 09:54:37","AP02SDTM":"2022-06-28 09:54:37","AP02EDTM":"2023-06-28 15:54:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-10","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2335,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.50025,"AVALU":"U/L","BASE2":9.48143,"BASE":1.50025,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-7.98118,"PCHG2":-84.17693,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2021-05-19 21:54:37","ADY":326,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-397","SUBJID":"id-397","SITEID":"BRA-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":11.66389,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-23","TRTSDTM":"2020-06-27 21:54:37","TRTEDTM":"2023-06-28 15:54:37","TRT01SDTM":"2020-06-27 21:54:37","TRT01EDTM":"2022-06-28 09:54:37","TRT02SDTM":"2022-06-28 09:54:37","TRT02EDTM":"2023-06-28 15:54:37","AP01SDTM":"2020-06-27 21:54:37","AP01EDTM":"2022-06-28 09:54:37","AP02SDTM":"2022-06-28 09:54:37","AP02EDTM":"2023-06-28 15:54:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-10","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6407,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.47122,"AVALU":"U/L","BASE2":9.48143,"BASE":1.50025,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.98979,"PCHG2":31.53314,"CHG":10.97097,"PCHG":731.27469,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-11-09 21:54:37","ADY":500,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-397","SUBJID":"id-397","SITEID":"BRA-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":11.66389,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-23","TRTSDTM":"2020-06-27 21:54:37","TRTEDTM":"2023-06-28 15:54:37","TRT01SDTM":"2020-06-27 21:54:37","TRT01EDTM":"2022-06-28 09:54:37","TRT02SDTM":"2022-06-28 09:54:37","TRT02EDTM":"2023-06-28 15:54:37","AP01SDTM":"2020-06-27 21:54:37","AP01EDTM":"2022-06-28 09:54:37","AP02SDTM":"2022-06-28 09:54:37","AP02EDTM":"2023-06-28 15:54:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-10","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5848,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.82699,"AVALU":"U/L","BASE2":9.48143,"BASE":1.50025,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.65444,"PCHG2":-17.44922,"CHG":6.32674,"PCHG":421.71167,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-01-14 21:54:37","ADY":566,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-397","SUBJID":"id-397","SITEID":"BRA-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":11.66389,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-23","TRTSDTM":"2020-06-27 21:54:37","TRTEDTM":"2023-06-28 15:54:37","TRT01SDTM":"2020-06-27 21:54:37","TRT01EDTM":"2022-06-28 09:54:37","TRT02SDTM":"2022-06-28 09:54:37","TRT02EDTM":"2023-06-28 15:54:37","AP01SDTM":"2020-06-27 21:54:37","AP01EDTM":"2022-06-28 09:54:37","AP02SDTM":"2022-06-28 09:54:37","AP02EDTM":"2023-06-28 15:54:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-10","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6775,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.74227,"AVALU":"U/L","BASE2":9.48143,"BASE":1.50025,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.26084,"PCHG2":192.5959,"CHG":26.24202,"PCHG":1749.17326,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-02-25 21:54:37","ADY":608,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-397","SUBJID":"id-397","SITEID":"BRA-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":11.66389,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-23","TRTSDTM":"2020-06-27 21:54:37","TRTEDTM":"2023-06-28 15:54:37","TRT01SDTM":"2020-06-27 21:54:37","TRT01EDTM":"2022-06-28 09:54:37","TRT02SDTM":"2022-06-28 09:54:37","TRT02EDTM":"2023-06-28 15:54:37","AP01SDTM":"2020-06-27 21:54:37","AP01EDTM":"2022-06-28 09:54:37","AP02SDTM":"2022-06-28 09:54:37","AP02EDTM":"2023-06-28 15:54:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-10","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3442,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.56607,"AVALU":"U/L","BASE2":9.48143,"BASE":1.50025,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":23.08464,"PCHG2":243.47217,"CHG":31.06582,"PCHG":2070.70562,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-06-22 21:54:37","ADY":725,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-397","SUBJID":"id-397","SITEID":"BRA-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":11.66389,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-23","TRTSDTM":"2020-06-27 21:54:37","TRTEDTM":"2023-06-28 15:54:37","TRT01SDTM":"2020-06-27 21:54:37","TRT01EDTM":"2022-06-28 09:54:37","TRT02SDTM":"2022-06-28 09:54:37","TRT02EDTM":"2023-06-28 15:54:37","AP01SDTM":"2020-06-27 21:54:37","AP01EDTM":"2022-06-28 09:54:37","AP02SDTM":"2022-06-28 09:54:37","AP02EDTM":"2023-06-28 15:54:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-10","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3665,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.67845,"AVALU":"U/L","BASE2":9.48143,"BASE":1.50025,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.19703,"PCHG2":107.54734,"CHG":18.1782,"PCHG":1211.67595,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2023-04-19 21:54:37","ADY":1026,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-397","SUBJID":"id-397","SITEID":"BRA-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":11.66389,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-23","TRTSDTM":"2020-06-27 21:54:37","TRTEDTM":"2023-06-28 15:54:37","TRT01SDTM":"2020-06-27 21:54:37","TRT01EDTM":"2022-06-28 09:54:37","TRT02SDTM":"2022-06-28 09:54:37","TRT02EDTM":"2023-06-28 15:54:37","AP01SDTM":"2020-06-27 21:54:37","AP01EDTM":"2022-06-28 09:54:37","AP02SDTM":"2022-06-28 09:54:37","AP02EDTM":"2023-06-28 15:54:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-10","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4113,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.56351,"AVALU":"mg/L","BASE2":8.56351,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-05-04 21:54:37","ADY":311,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-397","SUBJID":"id-397","SITEID":"BRA-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":11.66389,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-23","TRTSDTM":"2020-06-27 21:54:37","TRTEDTM":"2023-06-28 15:54:37","TRT01SDTM":"2020-06-27 21:54:37","TRT01EDTM":"2022-06-28 09:54:37","TRT02SDTM":"2022-06-28 09:54:37","TRT02EDTM":"2023-06-28 15:54:37","AP01SDTM":"2020-06-27 21:54:37","AP01EDTM":"2022-06-28 09:54:37","AP02SDTM":"2022-06-28 09:54:37","AP02EDTM":"2023-06-28 15:54:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-10","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2611,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.07248,"AVALU":"mg/L","BASE2":8.56351,"BASE":10.07248,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.50898,"PCHG2":17.62101,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2021-05-19 21:54:37","ADY":326,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-397","SUBJID":"id-397","SITEID":"BRA-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":11.66389,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-23","TRTSDTM":"2020-06-27 21:54:37","TRTEDTM":"2023-06-28 15:54:37","TRT01SDTM":"2020-06-27 21:54:37","TRT01EDTM":"2022-06-28 09:54:37","TRT02SDTM":"2022-06-28 09:54:37","TRT02EDTM":"2023-06-28 15:54:37","AP01SDTM":"2020-06-27 21:54:37","AP01EDTM":"2022-06-28 09:54:37","AP02SDTM":"2022-06-28 09:54:37","AP02EDTM":"2023-06-28 15:54:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-10","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2665,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.37148,"AVALU":"mg/L","BASE2":8.56351,"BASE":10.07248,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.80797,"PCHG2":9.43507,"CHG":-0.701,"PCHG":-6.95959,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-11-09 21:54:37","ADY":500,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-397","SUBJID":"id-397","SITEID":"BRA-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":11.66389,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-23","TRTSDTM":"2020-06-27 21:54:37","TRTEDTM":"2023-06-28 15:54:37","TRT01SDTM":"2020-06-27 21:54:37","TRT01EDTM":"2022-06-28 09:54:37","TRT02SDTM":"2022-06-28 09:54:37","TRT02EDTM":"2023-06-28 15:54:37","AP01SDTM":"2020-06-27 21:54:37","AP01EDTM":"2022-06-28 09:54:37","AP02SDTM":"2022-06-28 09:54:37","AP02EDTM":"2023-06-28 15:54:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-10","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6643,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.64243,"AVALU":"mg/L","BASE2":8.56351,"BASE":10.07248,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07892,"PCHG2":0.92162,"CHG":-1.43005,"PCHG":-14.19763,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-01-14 21:54:37","ADY":566,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-397","SUBJID":"id-397","SITEID":"BRA-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":11.66389,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-23","TRTSDTM":"2020-06-27 21:54:37","TRTEDTM":"2023-06-28 15:54:37","TRT01SDTM":"2020-06-27 21:54:37","TRT01EDTM":"2022-06-28 09:54:37","TRT02SDTM":"2022-06-28 09:54:37","TRT02EDTM":"2023-06-28 15:54:37","AP01SDTM":"2020-06-27 21:54:37","AP01EDTM":"2022-06-28 09:54:37","AP02SDTM":"2022-06-28 09:54:37","AP02EDTM":"2023-06-28 15:54:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-10","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6961,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.08579,"AVALU":"mg/L","BASE2":8.56351,"BASE":10.07248,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.52229,"PCHG2":6.09898,"CHG":-0.98669,"PCHG":-9.7959,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-02-25 21:54:37","ADY":608,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-397","SUBJID":"id-397","SITEID":"BRA-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":11.66389,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-23","TRTSDTM":"2020-06-27 21:54:37","TRTEDTM":"2023-06-28 15:54:37","TRT01SDTM":"2020-06-27 21:54:37","TRT01EDTM":"2022-06-28 09:54:37","TRT02SDTM":"2022-06-28 09:54:37","TRT02EDTM":"2023-06-28 15:54:37","AP01SDTM":"2020-06-27 21:54:37","AP01EDTM":"2022-06-28 09:54:37","AP02SDTM":"2022-06-28 09:54:37","AP02EDTM":"2023-06-28 15:54:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-10","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4086,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.94744,"AVALU":"mg/L","BASE2":8.56351,"BASE":10.07248,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.38394,"PCHG2":4.4834,"CHG":-1.12504,"PCHG":-11.16944,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-06-22 21:54:37","ADY":725,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-397","SUBJID":"id-397","SITEID":"BRA-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":11.66389,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-23","TRTSDTM":"2020-06-27 21:54:37","TRTEDTM":"2023-06-28 15:54:37","TRT01SDTM":"2020-06-27 21:54:37","TRT01EDTM":"2022-06-28 09:54:37","TRT02SDTM":"2022-06-28 09:54:37","TRT02EDTM":"2023-06-28 15:54:37","AP01SDTM":"2020-06-27 21:54:37","AP01EDTM":"2022-06-28 09:54:37","AP02SDTM":"2022-06-28 09:54:37","AP02EDTM":"2023-06-28 15:54:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-10","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7482,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.09736,"AVALU":"mg/L","BASE2":8.56351,"BASE":10.07248,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.53385,"PCHG2":17.9115,"CHG":0.02488,"PCHG":0.24697,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"2","ADTM":"2023-04-19 21:54:37","ADY":1026,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-397","SUBJID":"id-397","SITEID":"BRA-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":11.66389,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-23","TRTSDTM":"2020-06-27 21:54:37","TRTEDTM":"2023-06-28 15:54:37","TRT01SDTM":"2020-06-27 21:54:37","TRT01EDTM":"2022-06-28 09:54:37","TRT02SDTM":"2022-06-28 09:54:37","TRT02EDTM":"2023-06-28 15:54:37","AP01SDTM":"2020-06-27 21:54:37","AP01EDTM":"2022-06-28 09:54:37","AP02SDTM":"2022-06-28 09:54:37","AP02EDTM":"2023-06-28 15:54:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-10","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6777,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83244,"AVALU":"g/L","BASE2":2.83244,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-04 21:54:37","ADY":311,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-397","SUBJID":"id-397","SITEID":"BRA-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":11.66389,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-23","TRTSDTM":"2020-06-27 21:54:37","TRTEDTM":"2023-06-28 15:54:37","TRT01SDTM":"2020-06-27 21:54:37","TRT01EDTM":"2022-06-28 09:54:37","TRT02SDTM":"2022-06-28 09:54:37","TRT02EDTM":"2023-06-28 15:54:37","AP01SDTM":"2020-06-27 21:54:37","AP01EDTM":"2022-06-28 09:54:37","AP02SDTM":"2022-06-28 09:54:37","AP02EDTM":"2023-06-28 15:54:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-10","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4806,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89466,"AVALU":"g/L","BASE2":2.83244,"BASE":2.89466,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.06222,"PCHG2":2.19677,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-19 21:54:37","ADY":326,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-397","SUBJID":"id-397","SITEID":"BRA-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":11.66389,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-23","TRTSDTM":"2020-06-27 21:54:37","TRTEDTM":"2023-06-28 15:54:37","TRT01SDTM":"2020-06-27 21:54:37","TRT01EDTM":"2022-06-28 09:54:37","TRT02SDTM":"2022-06-28 09:54:37","TRT02EDTM":"2023-06-28 15:54:37","AP01SDTM":"2020-06-27 21:54:37","AP01EDTM":"2022-06-28 09:54:37","AP02SDTM":"2022-06-28 09:54:37","AP02EDTM":"2023-06-28 15:54:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-10","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6735,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03392,"AVALU":"g/L","BASE2":2.83244,"BASE":2.89466,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.20147,"PCHG2":7.11311,"CHG":0.13925,"PCHG":4.81067,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-11-09 21:54:37","ADY":500,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-397","SUBJID":"id-397","SITEID":"BRA-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":11.66389,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-23","TRTSDTM":"2020-06-27 21:54:37","TRTEDTM":"2023-06-28 15:54:37","TRT01SDTM":"2020-06-27 21:54:37","TRT01EDTM":"2022-06-28 09:54:37","TRT02SDTM":"2022-06-28 09:54:37","TRT02EDTM":"2023-06-28 15:54:37","AP01SDTM":"2020-06-27 21:54:37","AP01EDTM":"2022-06-28 09:54:37","AP02SDTM":"2022-06-28 09:54:37","AP02EDTM":"2023-06-28 15:54:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-10","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7829,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95158,"AVALU":"g/L","BASE2":2.83244,"BASE":2.89466,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11914,"PCHG2":4.20624,"CHG":0.05692,"PCHG":1.96628,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-14 21:54:37","ADY":566,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-397","SUBJID":"id-397","SITEID":"BRA-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":11.66389,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-23","TRTSDTM":"2020-06-27 21:54:37","TRTEDTM":"2023-06-28 15:54:37","TRT01SDTM":"2020-06-27 21:54:37","TRT01EDTM":"2022-06-28 09:54:37","TRT02SDTM":"2022-06-28 09:54:37","TRT02EDTM":"2023-06-28 15:54:37","AP01SDTM":"2020-06-27 21:54:37","AP01EDTM":"2022-06-28 09:54:37","AP02SDTM":"2022-06-28 09:54:37","AP02EDTM":"2023-06-28 15:54:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-10","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5070,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83047,"AVALU":"g/L","BASE2":2.83244,"BASE":2.89466,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00197,"PCHG2":-0.06967,"CHG":-0.0642,"PCHG":-2.21772,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-25 21:54:37","ADY":608,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-397","SUBJID":"id-397","SITEID":"BRA-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":11.66389,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-23","TRTSDTM":"2020-06-27 21:54:37","TRTEDTM":"2023-06-28 15:54:37","TRT01SDTM":"2020-06-27 21:54:37","TRT01EDTM":"2022-06-28 09:54:37","TRT02SDTM":"2022-06-28 09:54:37","TRT02EDTM":"2023-06-28 15:54:37","AP01SDTM":"2020-06-27 21:54:37","AP01EDTM":"2022-06-28 09:54:37","AP02SDTM":"2022-06-28 09:54:37","AP02EDTM":"2023-06-28 15:54:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-10","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":273,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88286,"AVALU":"g/L","BASE2":2.83244,"BASE":2.89466,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05042,"PCHG2":1.78009,"CHG":-0.0118,"PCHG":-0.40772,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-22 21:54:37","ADY":725,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-397","SUBJID":"id-397","SITEID":"BRA-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":11.66389,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-23","TRTSDTM":"2020-06-27 21:54:37","TRTEDTM":"2023-06-28 15:54:37","TRT01SDTM":"2020-06-27 21:54:37","TRT01EDTM":"2022-06-28 09:54:37","TRT02SDTM":"2022-06-28 09:54:37","TRT02EDTM":"2023-06-28 15:54:37","AP01SDTM":"2020-06-27 21:54:37","AP01EDTM":"2022-06-28 09:54:37","AP02SDTM":"2022-06-28 09:54:37","AP02EDTM":"2023-06-28 15:54:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-10","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2739,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89986,"AVALU":"g/L","BASE2":2.83244,"BASE":2.89466,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06742,"PCHG2":2.38017,"CHG":0.00519,"PCHG":0.17946,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-19 21:54:37","ADY":1026,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-50","SUBJID":"id-50","SITEID":"BRA-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.60612,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 04:49:14","TRTEDTM":"2022-04-27 22:49:14","TRT01SDTM":"2019-04-28 04:49:14","TRT01EDTM":"2021-04-27 16:49:14","TRT02SDTM":"2021-04-27 16:49:14","TRT02EDTM":"2022-04-27 22:49:14","AP01SDTM":"2019-04-28 04:49:14","AP01EDTM":"2021-04-27 16:49:14","AP02SDTM":"2021-04-27 16:49:14","AP02EDTM":"2022-04-27 22:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1232,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.87672,"AVALU":"U/L","BASE2":21.87672,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-09 04:49:14","ADY":72,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-50","SUBJID":"id-50","SITEID":"BRA-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.60612,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 04:49:14","TRTEDTM":"2022-04-27 22:49:14","TRT01SDTM":"2019-04-28 04:49:14","TRT01EDTM":"2021-04-27 16:49:14","TRT02SDTM":"2021-04-27 16:49:14","TRT02EDTM":"2022-04-27 22:49:14","AP01SDTM":"2019-04-28 04:49:14","AP01EDTM":"2021-04-27 16:49:14","AP02SDTM":"2021-04-27 16:49:14","AP02EDTM":"2022-04-27 22:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7157,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.01481,"AVALU":"U/L","BASE2":21.87672,"BASE":22.01481,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.13809,"PCHG2":0.63123,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-13 04:49:14","ADY":260,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-50","SUBJID":"id-50","SITEID":"BRA-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.60612,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 04:49:14","TRTEDTM":"2022-04-27 22:49:14","TRT01SDTM":"2019-04-28 04:49:14","TRT01EDTM":"2021-04-27 16:49:14","TRT02SDTM":"2021-04-27 16:49:14","TRT02EDTM":"2022-04-27 22:49:14","AP01SDTM":"2019-04-28 04:49:14","AP01EDTM":"2021-04-27 16:49:14","AP02SDTM":"2021-04-27 16:49:14","AP02EDTM":"2022-04-27 22:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5118,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.66416,"AVALU":"U/L","BASE2":21.87672,"BASE":22.01481,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.21256,"PCHG2":-32.9691,"CHG":-7.35065,"PCHG":-33.38956,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-17 04:49:14","ADY":264,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-50","SUBJID":"id-50","SITEID":"BRA-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.60612,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 04:49:14","TRTEDTM":"2022-04-27 22:49:14","TRT01SDTM":"2019-04-28 04:49:14","TRT01EDTM":"2021-04-27 16:49:14","TRT02SDTM":"2021-04-27 16:49:14","TRT02EDTM":"2022-04-27 22:49:14","AP01SDTM":"2019-04-28 04:49:14","AP01EDTM":"2021-04-27 16:49:14","AP02SDTM":"2021-04-27 16:49:14","AP02EDTM":"2022-04-27 22:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2444,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.22482,"AVALU":"U/L","BASE2":21.87672,"BASE":22.01481,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.34811,"PCHG2":15.30443,"CHG":3.21001,"PCHG":14.58116,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-01 04:49:14","ADY":308,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-50","SUBJID":"id-50","SITEID":"BRA-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.60612,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 04:49:14","TRTEDTM":"2022-04-27 22:49:14","TRT01SDTM":"2019-04-28 04:49:14","TRT01EDTM":"2021-04-27 16:49:14","TRT02SDTM":"2021-04-27 16:49:14","TRT02EDTM":"2022-04-27 22:49:14","AP01SDTM":"2019-04-28 04:49:14","AP01EDTM":"2021-04-27 16:49:14","AP02SDTM":"2021-04-27 16:49:14","AP02EDTM":"2022-04-27 22:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7151,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.6057,"AVALU":"U/L","BASE2":21.87672,"BASE":22.01481,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.27102,"PCHG2":-51.52062,"CHG":-11.40911,"PCHG":-51.82472,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-03 04:49:14","ADY":706,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-50","SUBJID":"id-50","SITEID":"BRA-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.60612,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 04:49:14","TRTEDTM":"2022-04-27 22:49:14","TRT01SDTM":"2019-04-28 04:49:14","TRT01EDTM":"2021-04-27 16:49:14","TRT02SDTM":"2021-04-27 16:49:14","TRT02EDTM":"2022-04-27 22:49:14","AP01SDTM":"2019-04-28 04:49:14","AP01EDTM":"2021-04-27 16:49:14","AP02SDTM":"2021-04-27 16:49:14","AP02EDTM":"2022-04-27 22:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2314,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.41059,"AVALU":"U/L","BASE2":21.87672,"BASE":22.01481,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.53387,"PCHG2":16.15359,"CHG":3.39578,"PCHG":15.42499,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-02 04:49:14","ADY":766,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-50","SUBJID":"id-50","SITEID":"BRA-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.60612,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 04:49:14","TRTEDTM":"2022-04-27 22:49:14","TRT01SDTM":"2019-04-28 04:49:14","TRT01EDTM":"2021-04-27 16:49:14","TRT02SDTM":"2021-04-27 16:49:14","TRT02EDTM":"2022-04-27 22:49:14","AP01SDTM":"2019-04-28 04:49:14","AP01EDTM":"2021-04-27 16:49:14","AP02SDTM":"2021-04-27 16:49:14","AP02EDTM":"2022-04-27 22:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5134,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.23451,"AVALU":"U/L","BASE2":21.87672,"BASE":22.01481,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.35779,"PCHG2":10.77764,"CHG":2.2197,"PCHG":10.08277,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-03 04:49:14","ADY":920,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-50","SUBJID":"id-50","SITEID":"BRA-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.60612,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 04:49:14","TRTEDTM":"2022-04-27 22:49:14","TRT01SDTM":"2019-04-28 04:49:14","TRT01EDTM":"2021-04-27 16:49:14","TRT02SDTM":"2021-04-27 16:49:14","TRT02EDTM":"2022-04-27 22:49:14","AP01SDTM":"2019-04-28 04:49:14","AP01EDTM":"2021-04-27 16:49:14","AP02SDTM":"2021-04-27 16:49:14","AP02EDTM":"2022-04-27 22:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2599,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.07881,"AVALU":"mg/L","BASE2":10.07881,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"4","BTOXGR":"0","ADTM":"2019-07-09 04:49:14","ADY":72,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-50","SUBJID":"id-50","SITEID":"BRA-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.60612,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 04:49:14","TRTEDTM":"2022-04-27 22:49:14","TRT01SDTM":"2019-04-28 04:49:14","TRT01EDTM":"2021-04-27 16:49:14","TRT02SDTM":"2021-04-27 16:49:14","TRT02EDTM":"2022-04-27 22:49:14","AP01SDTM":"2019-04-28 04:49:14","AP01EDTM":"2021-04-27 16:49:14","AP02SDTM":"2021-04-27 16:49:14","AP02EDTM":"2022-04-27 22:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3974,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.80314,"AVALU":"mg/L","BASE2":10.07881,"BASE":9.80314,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.27567,"PCHG2":-2.73515,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-13 04:49:14","ADY":260,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-50","SUBJID":"id-50","SITEID":"BRA-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.60612,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 04:49:14","TRTEDTM":"2022-04-27 22:49:14","TRT01SDTM":"2019-04-28 04:49:14","TRT01EDTM":"2021-04-27 16:49:14","TRT02SDTM":"2021-04-27 16:49:14","TRT02EDTM":"2022-04-27 22:49:14","AP01SDTM":"2019-04-28 04:49:14","AP01EDTM":"2021-04-27 16:49:14","AP02SDTM":"2021-04-27 16:49:14","AP02EDTM":"2022-04-27 22:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7613,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.85693,"AVALU":"mg/L","BASE2":10.07881,"BASE":9.80314,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.22188,"PCHG2":-12.12328,"CHG":-0.94621,"PCHG":-9.65213,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-17 04:49:14","ADY":264,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-50","SUBJID":"id-50","SITEID":"BRA-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.60612,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 04:49:14","TRTEDTM":"2022-04-27 22:49:14","TRT01SDTM":"2019-04-28 04:49:14","TRT01EDTM":"2021-04-27 16:49:14","TRT02SDTM":"2021-04-27 16:49:14","TRT02EDTM":"2022-04-27 22:49:14","AP01SDTM":"2019-04-28 04:49:14","AP01EDTM":"2021-04-27 16:49:14","AP02SDTM":"2021-04-27 16:49:14","AP02EDTM":"2022-04-27 22:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7391,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.94423,"AVALU":"mg/L","BASE2":10.07881,"BASE":9.80314,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.13458,"PCHG2":-11.25709,"CHG":-0.85891,"PCHG":-8.76158,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-01 04:49:14","ADY":308,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-50","SUBJID":"id-50","SITEID":"BRA-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.60612,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 04:49:14","TRTEDTM":"2022-04-27 22:49:14","TRT01SDTM":"2019-04-28 04:49:14","TRT01EDTM":"2021-04-27 16:49:14","TRT02SDTM":"2021-04-27 16:49:14","TRT02EDTM":"2022-04-27 22:49:14","AP01SDTM":"2019-04-28 04:49:14","AP01EDTM":"2021-04-27 16:49:14","AP02SDTM":"2021-04-27 16:49:14","AP02EDTM":"2022-04-27 22:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5009,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.23159,"AVALU":"mg/L","BASE2":10.07881,"BASE":9.80314,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.84722,"PCHG2":-18.32777,"CHG":-1.57155,"PCHG":-16.03109,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-03 04:49:14","ADY":706,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-50","SUBJID":"id-50","SITEID":"BRA-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.60612,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 04:49:14","TRTEDTM":"2022-04-27 22:49:14","TRT01SDTM":"2019-04-28 04:49:14","TRT01EDTM":"2021-04-27 16:49:14","TRT02SDTM":"2021-04-27 16:49:14","TRT02EDTM":"2022-04-27 22:49:14","AP01SDTM":"2019-04-28 04:49:14","AP01EDTM":"2021-04-27 16:49:14","AP02SDTM":"2021-04-27 16:49:14","AP02EDTM":"2022-04-27 22:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5709,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.20232,"AVALU":"mg/L","BASE2":10.07881,"BASE":9.80314,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.87649,"PCHG2":-18.6182,"CHG":-1.60082,"PCHG":-16.32969,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-02 04:49:14","ADY":766,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-50","SUBJID":"id-50","SITEID":"BRA-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.60612,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 04:49:14","TRTEDTM":"2022-04-27 22:49:14","TRT01SDTM":"2019-04-28 04:49:14","TRT01EDTM":"2021-04-27 16:49:14","TRT02SDTM":"2021-04-27 16:49:14","TRT02EDTM":"2022-04-27 22:49:14","AP01SDTM":"2019-04-28 04:49:14","AP01EDTM":"2021-04-27 16:49:14","AP02SDTM":"2021-04-27 16:49:14","AP02EDTM":"2022-04-27 22:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8381,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.53296,"AVALU":"mg/L","BASE2":10.07881,"BASE":9.80314,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.54585,"PCHG2":-25.25945,"CHG":-2.27018,"PCHG":-23.15769,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-11-03 04:49:14","ADY":920,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-50","SUBJID":"id-50","SITEID":"BRA-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.60612,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 04:49:14","TRTEDTM":"2022-04-27 22:49:14","TRT01SDTM":"2019-04-28 04:49:14","TRT01EDTM":"2021-04-27 16:49:14","TRT02SDTM":"2021-04-27 16:49:14","TRT02EDTM":"2022-04-27 22:49:14","AP01SDTM":"2019-04-28 04:49:14","AP01EDTM":"2021-04-27 16:49:14","AP02SDTM":"2021-04-27 16:49:14","AP02EDTM":"2022-04-27 22:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7962,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84558,"AVALU":"g/L","BASE2":2.84558,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-09 04:49:14","ADY":72,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-50","SUBJID":"id-50","SITEID":"BRA-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.60612,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 04:49:14","TRTEDTM":"2022-04-27 22:49:14","TRT01SDTM":"2019-04-28 04:49:14","TRT01EDTM":"2021-04-27 16:49:14","TRT02SDTM":"2021-04-27 16:49:14","TRT02EDTM":"2022-04-27 22:49:14","AP01SDTM":"2019-04-28 04:49:14","AP01EDTM":"2021-04-27 16:49:14","AP02SDTM":"2021-04-27 16:49:14","AP02EDTM":"2022-04-27 22:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8063,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91149,"AVALU":"g/L","BASE2":2.84558,"BASE":2.91149,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.06591,"PCHG2":2.31629,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-13 04:49:14","ADY":260,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-50","SUBJID":"id-50","SITEID":"BRA-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.60612,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 04:49:14","TRTEDTM":"2022-04-27 22:49:14","TRT01SDTM":"2019-04-28 04:49:14","TRT01EDTM":"2021-04-27 16:49:14","TRT02SDTM":"2021-04-27 16:49:14","TRT02EDTM":"2022-04-27 22:49:14","AP01SDTM":"2019-04-28 04:49:14","AP01EDTM":"2021-04-27 16:49:14","AP02SDTM":"2021-04-27 16:49:14","AP02EDTM":"2022-04-27 22:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2078,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95783,"AVALU":"g/L","BASE2":2.84558,"BASE":2.91149,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11225,"PCHG2":3.94477,"CHG":0.04634,"PCHG":1.59161,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-17 04:49:14","ADY":264,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-50","SUBJID":"id-50","SITEID":"BRA-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.60612,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 04:49:14","TRTEDTM":"2022-04-27 22:49:14","TRT01SDTM":"2019-04-28 04:49:14","TRT01EDTM":"2021-04-27 16:49:14","TRT02SDTM":"2021-04-27 16:49:14","TRT02EDTM":"2022-04-27 22:49:14","AP01SDTM":"2019-04-28 04:49:14","AP01EDTM":"2021-04-27 16:49:14","AP02SDTM":"2021-04-27 16:49:14","AP02EDTM":"2022-04-27 22:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8275,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80276,"AVALU":"g/L","BASE2":2.84558,"BASE":2.91149,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04282,"PCHG2":-1.50471,"CHG":-0.10873,"PCHG":-3.7345,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-01 04:49:14","ADY":308,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-50","SUBJID":"id-50","SITEID":"BRA-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.60612,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 04:49:14","TRTEDTM":"2022-04-27 22:49:14","TRT01SDTM":"2019-04-28 04:49:14","TRT01EDTM":"2021-04-27 16:49:14","TRT02SDTM":"2021-04-27 16:49:14","TRT02EDTM":"2022-04-27 22:49:14","AP01SDTM":"2019-04-28 04:49:14","AP01EDTM":"2021-04-27 16:49:14","AP02SDTM":"2021-04-27 16:49:14","AP02EDTM":"2022-04-27 22:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2803,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.07218,"AVALU":"g/L","BASE2":2.84558,"BASE":2.91149,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.2266,"PCHG2":7.96334,"CHG":0.16069,"PCHG":5.51921,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-04-03 04:49:14","ADY":706,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-50","SUBJID":"id-50","SITEID":"BRA-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.60612,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 04:49:14","TRTEDTM":"2022-04-27 22:49:14","TRT01SDTM":"2019-04-28 04:49:14","TRT01EDTM":"2021-04-27 16:49:14","TRT02SDTM":"2021-04-27 16:49:14","TRT02EDTM":"2022-04-27 22:49:14","AP01SDTM":"2019-04-28 04:49:14","AP01EDTM":"2021-04-27 16:49:14","AP02SDTM":"2021-04-27 16:49:14","AP02EDTM":"2022-04-27 22:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4873,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99832,"AVALU":"g/L","BASE2":2.84558,"BASE":2.91149,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15274,"PCHG2":5.36759,"CHG":0.08683,"PCHG":2.98222,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-02 04:49:14","ADY":766,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-50","SUBJID":"id-50","SITEID":"BRA-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.60612,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 04:49:14","TRTEDTM":"2022-04-27 22:49:14","TRT01SDTM":"2019-04-28 04:49:14","TRT01EDTM":"2021-04-27 16:49:14","TRT02SDTM":"2021-04-27 16:49:14","TRT02EDTM":"2022-04-27 22:49:14","AP01SDTM":"2019-04-28 04:49:14","AP01EDTM":"2021-04-27 16:49:14","AP02SDTM":"2021-04-27 16:49:14","AP02EDTM":"2022-04-27 22:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2580,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94681,"AVALU":"g/L","BASE2":2.84558,"BASE":2.91149,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10123,"PCHG2":3.55738,"CHG":0.03532,"PCHG":1.21299,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-03 04:49:14","ADY":920,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-9","SUBJID":"id-9","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":7.0163,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-24","TRTSDTM":"2019-03-25 23:40:59","TRTEDTM":"2022-02-13 00:31:35","TRT01SDTM":"2019-03-25 23:40:59","TRT01EDTM":"2021-02-12 18:31:35","TRT02SDTM":"2021-02-12 18:31:35","TRT02EDTM":"2022-02-13 00:31:35","AP01SDTM":"2019-03-25 23:40:59","AP01EDTM":"2021-02-12 18:31:35","AP02SDTM":"2021-02-12 18:31:35","AP02EDTM":"2022-02-13 00:31:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1056,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":1091,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":910,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.8381,"AVALU":"U/L","BASE2":17.8381,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-06-01 23:40:59","ADY":68,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-9","SUBJID":"id-9","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":7.0163,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-24","TRTSDTM":"2019-03-25 23:40:59","TRTEDTM":"2022-02-13 00:31:35","TRT01SDTM":"2019-03-25 23:40:59","TRT01EDTM":"2021-02-12 18:31:35","TRT02SDTM":"2021-02-12 18:31:35","TRT02EDTM":"2022-02-13 00:31:35","AP01SDTM":"2019-03-25 23:40:59","AP01EDTM":"2021-02-12 18:31:35","AP02SDTM":"2021-02-12 18:31:35","AP02EDTM":"2022-02-13 00:31:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1056,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":1091,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2816,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.77952,"AVALU":"U/L","BASE2":17.8381,"BASE":30.77952,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":12.94143,"PCHG2":72.54937,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-16 23:40:59","ADY":297,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-9","SUBJID":"id-9","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":7.0163,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-24","TRTSDTM":"2019-03-25 23:40:59","TRTEDTM":"2022-02-13 00:31:35","TRT01SDTM":"2019-03-25 23:40:59","TRT01EDTM":"2021-02-12 18:31:35","TRT02SDTM":"2021-02-12 18:31:35","TRT02EDTM":"2022-02-13 00:31:35","AP01SDTM":"2019-03-25 23:40:59","AP01EDTM":"2021-02-12 18:31:35","AP02SDTM":"2021-02-12 18:31:35","AP02EDTM":"2022-02-13 00:31:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1056,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":1091,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3195,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.78412,"AVALU":"U/L","BASE2":17.8381,"BASE":30.77952,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.94602,"PCHG2":66.96915,"CHG":-0.99541,"PCHG":-3.23399,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-28 23:40:59","ADY":522,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-9","SUBJID":"id-9","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":7.0163,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-24","TRTSDTM":"2019-03-25 23:40:59","TRTEDTM":"2022-02-13 00:31:35","TRT01SDTM":"2019-03-25 23:40:59","TRT01EDTM":"2021-02-12 18:31:35","TRT02SDTM":"2021-02-12 18:31:35","TRT02EDTM":"2022-02-13 00:31:35","AP01SDTM":"2019-03-25 23:40:59","AP01EDTM":"2021-02-12 18:31:35","AP02SDTM":"2021-02-12 18:31:35","AP02EDTM":"2022-02-13 00:31:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1056,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":1091,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5431,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.39232,"AVALU":"U/L","BASE2":17.8381,"BASE":30.77952,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.44578,"PCHG2":-75.37676,"CHG":-26.38721,"PCHG":-85.72974,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-09-03 23:40:59","ADY":528,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-9","SUBJID":"id-9","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":7.0163,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-24","TRTSDTM":"2019-03-25 23:40:59","TRTEDTM":"2022-02-13 00:31:35","TRT01SDTM":"2019-03-25 23:40:59","TRT01EDTM":"2021-02-12 18:31:35","TRT02SDTM":"2021-02-12 18:31:35","TRT02EDTM":"2022-02-13 00:31:35","AP01SDTM":"2019-03-25 23:40:59","AP01EDTM":"2021-02-12 18:31:35","AP02SDTM":"2021-02-12 18:31:35","AP02EDTM":"2022-02-13 00:31:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1056,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":1091,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2068,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.58514,"AVALU":"U/L","BASE2":17.8381,"BASE":30.77952,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.74705,"PCHG2":32.21782,"CHG":-7.19438,"PCHG":-23.37392,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-03 23:40:59","ADY":801,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-9","SUBJID":"id-9","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":7.0163,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-24","TRTSDTM":"2019-03-25 23:40:59","TRTEDTM":"2022-02-13 00:31:35","TRT01SDTM":"2019-03-25 23:40:59","TRT01EDTM":"2021-02-12 18:31:35","TRT02SDTM":"2021-02-12 18:31:35","TRT02EDTM":"2022-02-13 00:31:35","AP01SDTM":"2019-03-25 23:40:59","AP01EDTM":"2021-02-12 18:31:35","AP02SDTM":"2021-02-12 18:31:35","AP02EDTM":"2022-02-13 00:31:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1056,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":1091,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4545,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.29504,"AVALU":"U/L","BASE2":17.8381,"BASE":30.77952,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.54306,"PCHG2":-8.65034,"CHG":-14.48448,"PCHG":-47.05883,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-07 23:40:59","ADY":958,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-9","SUBJID":"id-9","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":7.0163,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-24","TRTSDTM":"2019-03-25 23:40:59","TRTEDTM":"2022-02-13 00:31:35","TRT01SDTM":"2019-03-25 23:40:59","TRT01EDTM":"2021-02-12 18:31:35","TRT02SDTM":"2021-02-12 18:31:35","TRT02EDTM":"2022-02-13 00:31:35","AP01SDTM":"2019-03-25 23:40:59","AP01EDTM":"2021-02-12 18:31:35","AP02SDTM":"2021-02-12 18:31:35","AP02EDTM":"2022-02-13 00:31:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1056,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":1091,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4989,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.73413,"AVALU":"U/L","BASE2":17.8381,"BASE":30.77952,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.89603,"PCHG2":49.87095,"CHG":-4.0454,"PCHG":-13.14315,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-12 23:40:59","ADY":1024,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-9","SUBJID":"id-9","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":7.0163,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-24","TRTSDTM":"2019-03-25 23:40:59","TRTEDTM":"2022-02-13 00:31:35","TRT01SDTM":"2019-03-25 23:40:59","TRT01EDTM":"2021-02-12 18:31:35","TRT02SDTM":"2021-02-12 18:31:35","TRT02EDTM":"2022-02-13 00:31:35","AP01SDTM":"2019-03-25 23:40:59","AP01EDTM":"2021-02-12 18:31:35","AP02SDTM":"2021-02-12 18:31:35","AP02EDTM":"2022-02-13 00:31:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1056,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":1091,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6784,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.55556,"AVALU":"mg/L","BASE2":10.55556,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2019-06-01 23:40:59","ADY":68,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-9","SUBJID":"id-9","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":7.0163,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-24","TRTSDTM":"2019-03-25 23:40:59","TRTEDTM":"2022-02-13 00:31:35","TRT01SDTM":"2019-03-25 23:40:59","TRT01EDTM":"2021-02-12 18:31:35","TRT02SDTM":"2021-02-12 18:31:35","TRT02EDTM":"2022-02-13 00:31:35","AP01SDTM":"2019-03-25 23:40:59","AP01EDTM":"2021-02-12 18:31:35","AP02SDTM":"2021-02-12 18:31:35","AP02EDTM":"2022-02-13 00:31:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1056,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":1091,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":41,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.87676,"AVALU":"mg/L","BASE2":10.55556,"BASE":8.87676,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.6788,"PCHG2":-15.90439,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-16 23:40:59","ADY":297,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-9","SUBJID":"id-9","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":7.0163,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-24","TRTSDTM":"2019-03-25 23:40:59","TRTEDTM":"2022-02-13 00:31:35","TRT01SDTM":"2019-03-25 23:40:59","TRT01EDTM":"2021-02-12 18:31:35","TRT02SDTM":"2021-02-12 18:31:35","TRT02EDTM":"2022-02-13 00:31:35","AP01SDTM":"2019-03-25 23:40:59","AP01EDTM":"2021-02-12 18:31:35","AP02SDTM":"2021-02-12 18:31:35","AP02EDTM":"2022-02-13 00:31:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1056,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":1091,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3738,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.73293,"AVALU":"mg/L","BASE2":10.55556,"BASE":8.87676,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.82263,"PCHG2":-26.74067,"CHG":-1.14383,"PCHG":-12.88567,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-08-28 23:40:59","ADY":522,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-9","SUBJID":"id-9","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":7.0163,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-24","TRTSDTM":"2019-03-25 23:40:59","TRTEDTM":"2022-02-13 00:31:35","TRT01SDTM":"2019-03-25 23:40:59","TRT01EDTM":"2021-02-12 18:31:35","TRT02SDTM":"2021-02-12 18:31:35","TRT02EDTM":"2022-02-13 00:31:35","AP01SDTM":"2019-03-25 23:40:59","AP01EDTM":"2021-02-12 18:31:35","AP02SDTM":"2021-02-12 18:31:35","AP02EDTM":"2022-02-13 00:31:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1056,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":1091,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7021,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.33908,"AVALU":"mg/L","BASE2":10.55556,"BASE":8.87676,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.21648,"PCHG2":-11.52454,"CHG":0.46232,"PCHG":5.20818,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-03 23:40:59","ADY":528,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-9","SUBJID":"id-9","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":7.0163,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-24","TRTSDTM":"2019-03-25 23:40:59","TRTEDTM":"2022-02-13 00:31:35","TRT01SDTM":"2019-03-25 23:40:59","TRT01EDTM":"2021-02-12 18:31:35","TRT02SDTM":"2021-02-12 18:31:35","TRT02EDTM":"2022-02-13 00:31:35","AP01SDTM":"2019-03-25 23:40:59","AP01EDTM":"2021-02-12 18:31:35","AP02SDTM":"2021-02-12 18:31:35","AP02EDTM":"2022-02-13 00:31:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1056,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":1091,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7360,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.76385,"AVALU":"mg/L","BASE2":10.55556,"BASE":8.87676,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.79172,"PCHG2":-7.50047,"CHG":0.88708,"PCHG":9.9933,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-03 23:40:59","ADY":801,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-9","SUBJID":"id-9","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":7.0163,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-24","TRTSDTM":"2019-03-25 23:40:59","TRTEDTM":"2022-02-13 00:31:35","TRT01SDTM":"2019-03-25 23:40:59","TRT01EDTM":"2021-02-12 18:31:35","TRT02SDTM":"2021-02-12 18:31:35","TRT02EDTM":"2022-02-13 00:31:35","AP01SDTM":"2019-03-25 23:40:59","AP01EDTM":"2021-02-12 18:31:35","AP02SDTM":"2021-02-12 18:31:35","AP02EDTM":"2022-02-13 00:31:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1056,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":1091,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3740,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.19629,"AVALU":"mg/L","BASE2":10.55556,"BASE":8.87676,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.35928,"PCHG2":-12.87734,"CHG":0.31952,"PCHG":3.59953,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-07 23:40:59","ADY":958,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-9","SUBJID":"id-9","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":7.0163,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-24","TRTSDTM":"2019-03-25 23:40:59","TRTEDTM":"2022-02-13 00:31:35","TRT01SDTM":"2019-03-25 23:40:59","TRT01EDTM":"2021-02-12 18:31:35","TRT02SDTM":"2021-02-12 18:31:35","TRT02EDTM":"2022-02-13 00:31:35","AP01SDTM":"2019-03-25 23:40:59","AP01EDTM":"2021-02-12 18:31:35","AP02SDTM":"2021-02-12 18:31:35","AP02EDTM":"2022-02-13 00:31:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1056,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":1091,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1444,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.52599,"AVALU":"mg/L","BASE2":10.55556,"BASE":8.87676,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.02957,"PCHG2":-19.22748,"CHG":-0.35077,"PCHG":-3.95156,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-12 23:40:59","ADY":1024,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-9","SUBJID":"id-9","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":7.0163,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-24","TRTSDTM":"2019-03-25 23:40:59","TRTEDTM":"2022-02-13 00:31:35","TRT01SDTM":"2019-03-25 23:40:59","TRT01EDTM":"2021-02-12 18:31:35","TRT02SDTM":"2021-02-12 18:31:35","TRT02EDTM":"2022-02-13 00:31:35","AP01SDTM":"2019-03-25 23:40:59","AP01EDTM":"2021-02-12 18:31:35","AP02SDTM":"2021-02-12 18:31:35","AP02EDTM":"2022-02-13 00:31:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1056,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":1091,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5384,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91045,"AVALU":"g/L","BASE2":2.91045,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-06-01 23:40:59","ADY":68,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-9","SUBJID":"id-9","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":7.0163,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-24","TRTSDTM":"2019-03-25 23:40:59","TRTEDTM":"2022-02-13 00:31:35","TRT01SDTM":"2019-03-25 23:40:59","TRT01EDTM":"2021-02-12 18:31:35","TRT02SDTM":"2021-02-12 18:31:35","TRT02EDTM":"2022-02-13 00:31:35","AP01SDTM":"2019-03-25 23:40:59","AP01EDTM":"2021-02-12 18:31:35","AP02SDTM":"2021-02-12 18:31:35","AP02EDTM":"2022-02-13 00:31:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1056,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":1091,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4584,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.6515,"AVALU":"g/L","BASE2":2.91045,"BASE":2.6515,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.25895,"PCHG2":-8.89736,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-16 23:40:59","ADY":297,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-9","SUBJID":"id-9","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":7.0163,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-24","TRTSDTM":"2019-03-25 23:40:59","TRTEDTM":"2022-02-13 00:31:35","TRT01SDTM":"2019-03-25 23:40:59","TRT01EDTM":"2021-02-12 18:31:35","TRT02SDTM":"2021-02-12 18:31:35","TRT02EDTM":"2022-02-13 00:31:35","AP01SDTM":"2019-03-25 23:40:59","AP01EDTM":"2021-02-12 18:31:35","AP02SDTM":"2021-02-12 18:31:35","AP02EDTM":"2022-02-13 00:31:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1056,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":1091,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5811,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9313,"AVALU":"g/L","BASE2":2.91045,"BASE":2.6515,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02084,"PCHG2":0.71618,"CHG":0.2798,"PCHG":10.55243,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-28 23:40:59","ADY":522,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-9","SUBJID":"id-9","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":7.0163,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-24","TRTSDTM":"2019-03-25 23:40:59","TRTEDTM":"2022-02-13 00:31:35","TRT01SDTM":"2019-03-25 23:40:59","TRT01EDTM":"2021-02-12 18:31:35","TRT02SDTM":"2021-02-12 18:31:35","TRT02EDTM":"2022-02-13 00:31:35","AP01SDTM":"2019-03-25 23:40:59","AP01EDTM":"2021-02-12 18:31:35","AP02SDTM":"2021-02-12 18:31:35","AP02EDTM":"2022-02-13 00:31:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1056,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":1091,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5932,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91034,"AVALU":"g/L","BASE2":2.91045,"BASE":2.6515,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00011,"PCHG2":-0.00392,"CHG":0.25884,"PCHG":9.762,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-03 23:40:59","ADY":528,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-9","SUBJID":"id-9","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":7.0163,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-24","TRTSDTM":"2019-03-25 23:40:59","TRTEDTM":"2022-02-13 00:31:35","TRT01SDTM":"2019-03-25 23:40:59","TRT01EDTM":"2021-02-12 18:31:35","TRT02SDTM":"2021-02-12 18:31:35","TRT02EDTM":"2022-02-13 00:31:35","AP01SDTM":"2019-03-25 23:40:59","AP01EDTM":"2021-02-12 18:31:35","AP02SDTM":"2021-02-12 18:31:35","AP02EDTM":"2022-02-13 00:31:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1056,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":1091,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7423,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79548,"AVALU":"g/L","BASE2":2.91045,"BASE":2.6515,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11497,"PCHG2":-3.95019,"CHG":0.14399,"PCHG":5.43033,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-03 23:40:59","ADY":801,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-9","SUBJID":"id-9","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":7.0163,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-24","TRTSDTM":"2019-03-25 23:40:59","TRTEDTM":"2022-02-13 00:31:35","TRT01SDTM":"2019-03-25 23:40:59","TRT01EDTM":"2021-02-12 18:31:35","TRT02SDTM":"2021-02-12 18:31:35","TRT02EDTM":"2022-02-13 00:31:35","AP01SDTM":"2019-03-25 23:40:59","AP01EDTM":"2021-02-12 18:31:35","AP02SDTM":"2021-02-12 18:31:35","AP02EDTM":"2022-02-13 00:31:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1056,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":1091,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5206,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80852,"AVALU":"g/L","BASE2":2.91045,"BASE":2.6515,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10193,"PCHG2":-3.50222,"CHG":0.15702,"PCHG":5.92204,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-07 23:40:59","ADY":958,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-11-id-9","SUBJID":"id-9","SITEID":"BRA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-11","INVNAM":"Dr. BRA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":7.0163,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-24","TRTSDTM":"2019-03-25 23:40:59","TRTEDTM":"2022-02-13 00:31:35","TRT01SDTM":"2019-03-25 23:40:59","TRT01EDTM":"2021-02-12 18:31:35","TRT02SDTM":"2021-02-12 18:31:35","TRT02EDTM":"2022-02-13 00:31:35","AP01SDTM":"2019-03-25 23:40:59","AP01EDTM":"2021-02-12 18:31:35","AP02SDTM":"2021-02-12 18:31:35","AP02EDTM":"2022-02-13 00:31:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1056,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":1091,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2793,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8345,"AVALU":"g/L","BASE2":2.91045,"BASE":2.6515,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07595,"PCHG2":-2.60951,"CHG":0.183,"PCHG":6.90194,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-12 23:40:59","ADY":1024,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-12-id-59","SUBJID":"id-59","SITEID":"BRA-12","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-12","INVNAM":"Dr. BRA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":11.1938,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-23","TRTSDTM":"2019-11-25 23:42:12","TRT01SDTM":"2019-11-25 23:42:12","AP01SDTM":"2019-11-25 23:42:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8071,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.17396,"AVALU":"U/L","BASE2":18.17396,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-15 23:42:12","ADY":20,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-12-id-59","SUBJID":"id-59","SITEID":"BRA-12","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-12","INVNAM":"Dr. BRA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":11.1938,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-23","TRTSDTM":"2019-11-25 23:42:12","TRT01SDTM":"2019-11-25 23:42:12","AP01SDTM":"2019-11-25 23:42:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2002,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.03946,"AVALU":"U/L","BASE2":18.17396,"BASE":10.03946,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-8.1345,"PCHG2":-44.75908,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-03 23:42:12","ADY":252,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-12-id-59","SUBJID":"id-59","SITEID":"BRA-12","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-12","INVNAM":"Dr. BRA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":11.1938,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-23","TRTSDTM":"2019-11-25 23:42:12","TRT01SDTM":"2019-11-25 23:42:12","AP01SDTM":"2019-11-25 23:42:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3271,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.8686,"AVALU":"U/L","BASE2":18.17396,"BASE":10.03946,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.69464,"PCHG2":86.35787,"CHG":23.82914,"PCHG":237.35474,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-20 23:42:12","ADY":391,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-12-id-59","SUBJID":"id-59","SITEID":"BRA-12","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-12","INVNAM":"Dr. BRA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":11.1938,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-23","TRTSDTM":"2019-11-25 23:42:12","TRT01SDTM":"2019-11-25 23:42:12","AP01SDTM":"2019-11-25 23:42:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4518,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.85802,"AVALU":"U/L","BASE2":18.17396,"BASE":10.03946,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.31593,"PCHG2":-34.75266,"CHG":1.81856,"PCHG":18.11413,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-21 23:42:12","ADY":423,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-12-id-59","SUBJID":"id-59","SITEID":"BRA-12","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-12","INVNAM":"Dr. BRA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":11.1938,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-23","TRTSDTM":"2019-11-25 23:42:12","TRT01SDTM":"2019-11-25 23:42:12","AP01SDTM":"2019-11-25 23:42:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":580,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.73739,"AVALU":"U/L","BASE2":18.17396,"BASE":10.03946,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.43657,"PCHG2":-2.40215,"CHG":7.69793,"PCHG":76.67672,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-26 23:42:12","ADY":548,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-12-id-59","SUBJID":"id-59","SITEID":"BRA-12","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-12","INVNAM":"Dr. BRA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":11.1938,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-23","TRTSDTM":"2019-11-25 23:42:12","TRT01SDTM":"2019-11-25 23:42:12","AP01SDTM":"2019-11-25 23:42:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7274,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.4369,"AVALU":"U/L","BASE2":18.17396,"BASE":10.03946,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.26295,"PCHG2":83.98252,"CHG":23.39744,"PCHG":233.05476,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-30 23:42:12","ADY":552,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-12-id-59","SUBJID":"id-59","SITEID":"BRA-12","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-12","INVNAM":"Dr. BRA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":11.1938,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-23","TRTSDTM":"2019-11-25 23:42:12","TRT01SDTM":"2019-11-25 23:42:12","AP01SDTM":"2019-11-25 23:42:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6201,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.22784,"AVALU":"U/L","BASE2":18.17396,"BASE":10.03946,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.94612,"PCHG2":-21.71302,"CHG":4.18838,"PCHG":41.71917,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-12 23:42:12","ADY":718,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-12-id-59","SUBJID":"id-59","SITEID":"BRA-12","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-12","INVNAM":"Dr. BRA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":11.1938,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-23","TRTSDTM":"2019-11-25 23:42:12","TRT01SDTM":"2019-11-25 23:42:12","AP01SDTM":"2019-11-25 23:42:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7987,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.34689,"AVALU":"mg/L","BASE2":9.34689,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-15 23:42:12","ADY":20,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-12-id-59","SUBJID":"id-59","SITEID":"BRA-12","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-12","INVNAM":"Dr. BRA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":11.1938,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-23","TRTSDTM":"2019-11-25 23:42:12","TRT01SDTM":"2019-11-25 23:42:12","AP01SDTM":"2019-11-25 23:42:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":84,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.33979,"AVALU":"mg/L","BASE2":9.34689,"BASE":8.33979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.00711,"PCHG2":-10.77476,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-03 23:42:12","ADY":252,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-12-id-59","SUBJID":"id-59","SITEID":"BRA-12","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-12","INVNAM":"Dr. BRA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":11.1938,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-23","TRTSDTM":"2019-11-25 23:42:12","TRT01SDTM":"2019-11-25 23:42:12","AP01SDTM":"2019-11-25 23:42:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8056,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.27131,"AVALU":"mg/L","BASE2":9.34689,"BASE":8.33979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07559,"PCHG2":-0.80868,"CHG":0.93152,"PCHG":11.16958,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-20 23:42:12","ADY":391,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-12-id-59","SUBJID":"id-59","SITEID":"BRA-12","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-12","INVNAM":"Dr. BRA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":11.1938,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-23","TRTSDTM":"2019-11-25 23:42:12","TRT01SDTM":"2019-11-25 23:42:12","AP01SDTM":"2019-11-25 23:42:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7986,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.38263,"AVALU":"mg/L","BASE2":9.34689,"BASE":8.33979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03574,"PCHG2":0.38234,"CHG":1.04284,"PCHG":12.50443,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-21 23:42:12","ADY":423,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-12-id-59","SUBJID":"id-59","SITEID":"BRA-12","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-12","INVNAM":"Dr. BRA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":11.1938,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-23","TRTSDTM":"2019-11-25 23:42:12","TRT01SDTM":"2019-11-25 23:42:12","AP01SDTM":"2019-11-25 23:42:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":438,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.35845,"AVALU":"mg/L","BASE2":9.34689,"BASE":8.33979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01155,"PCHG2":0.12358,"CHG":1.01866,"PCHG":12.21441,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-26 23:42:12","ADY":548,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-12-id-59","SUBJID":"id-59","SITEID":"BRA-12","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-12","INVNAM":"Dr. BRA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":11.1938,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-23","TRTSDTM":"2019-11-25 23:42:12","TRT01SDTM":"2019-11-25 23:42:12","AP01SDTM":"2019-11-25 23:42:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7363,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.43101,"AVALU":"mg/L","BASE2":9.34689,"BASE":8.33979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08412,"PCHG2":0.89997,"CHG":1.09123,"PCHG":13.08456,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-30 23:42:12","ADY":552,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-12-id-59","SUBJID":"id-59","SITEID":"BRA-12","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-12","INVNAM":"Dr. BRA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":11.1938,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-23","TRTSDTM":"2019-11-25 23:42:12","TRT01SDTM":"2019-11-25 23:42:12","AP01SDTM":"2019-11-25 23:42:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4378,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.54298,"AVALU":"mg/L","BASE2":9.34689,"BASE":8.33979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.80391,"PCHG2":-19.29958,"CHG":-0.79681,"PCHG":-9.55426,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-11-12 23:42:12","ADY":718,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-12-id-59","SUBJID":"id-59","SITEID":"BRA-12","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-12","INVNAM":"Dr. BRA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":11.1938,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-23","TRTSDTM":"2019-11-25 23:42:12","TRT01SDTM":"2019-11-25 23:42:12","AP01SDTM":"2019-11-25 23:42:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1038,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84463,"AVALU":"g/L","BASE2":2.84463,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-15 23:42:12","ADY":20,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-12-id-59","SUBJID":"id-59","SITEID":"BRA-12","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-12","INVNAM":"Dr. BRA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":11.1938,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-23","TRTSDTM":"2019-11-25 23:42:12","TRT01SDTM":"2019-11-25 23:42:12","AP01SDTM":"2019-11-25 23:42:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4245,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96893,"AVALU":"g/L","BASE2":2.84463,"BASE":2.96893,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.1243,"PCHG2":4.36952,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-03 23:42:12","ADY":252,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-12-id-59","SUBJID":"id-59","SITEID":"BRA-12","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-12","INVNAM":"Dr. BRA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":11.1938,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-23","TRTSDTM":"2019-11-25 23:42:12","TRT01SDTM":"2019-11-25 23:42:12","AP01SDTM":"2019-11-25 23:42:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6529,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05808,"AVALU":"g/L","BASE2":2.84463,"BASE":2.96893,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.21345,"PCHG2":7.50348,"CHG":0.08915,"PCHG":3.00275,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-12-20 23:42:12","ADY":391,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-12-id-59","SUBJID":"id-59","SITEID":"BRA-12","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-12","INVNAM":"Dr. BRA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":11.1938,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-23","TRTSDTM":"2019-11-25 23:42:12","TRT01SDTM":"2019-11-25 23:42:12","AP01SDTM":"2019-11-25 23:42:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6395,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92497,"AVALU":"g/L","BASE2":2.84463,"BASE":2.96893,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08033,"PCHG2":2.82402,"CHG":-0.04396,"PCHG":-1.4808,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-21 23:42:12","ADY":423,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-12-id-59","SUBJID":"id-59","SITEID":"BRA-12","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-12","INVNAM":"Dr. BRA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":11.1938,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-23","TRTSDTM":"2019-11-25 23:42:12","TRT01SDTM":"2019-11-25 23:42:12","AP01SDTM":"2019-11-25 23:42:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8161,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8223,"AVALU":"g/L","BASE2":2.84463,"BASE":2.96893,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02233,"PCHG2":-0.78507,"CHG":-0.14663,"PCHG":-4.93879,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-26 23:42:12","ADY":548,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-12-id-59","SUBJID":"id-59","SITEID":"BRA-12","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-12","INVNAM":"Dr. BRA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":11.1938,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-23","TRTSDTM":"2019-11-25 23:42:12","TRT01SDTM":"2019-11-25 23:42:12","AP01SDTM":"2019-11-25 23:42:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5258,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02686,"AVALU":"g/L","BASE2":2.84463,"BASE":2.96893,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18223,"PCHG2":6.40602,"CHG":0.05793,"PCHG":1.95124,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-05-30 23:42:12","ADY":552,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-12-id-59","SUBJID":"id-59","SITEID":"BRA-12","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-12","INVNAM":"Dr. BRA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":11.1938,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-23","TRTSDTM":"2019-11-25 23:42:12","TRT01SDTM":"2019-11-25 23:42:12","AP01SDTM":"2019-11-25 23:42:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6512,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91669,"AVALU":"g/L","BASE2":2.84463,"BASE":2.96893,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07206,"PCHG2":2.53304,"CHG":-0.05224,"PCHG":-1.7596,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-12 23:42:12","ADY":718,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-13-id-177","SUBJID":"id-177","SITEID":"BRA-13","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-13","INVNAM":"Dr. BRA-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":12.71923,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-27","TRTSDTM":"2020-08-30 08:45:46","TRTEDTM":"2023-08-31 02:45:46","TRT01SDTM":"2020-08-30 08:45:46","TRT01EDTM":"2022-08-30 20:45:46","TRT02SDTM":"2022-08-30 20:45:46","TRT02EDTM":"2023-08-31 02:45:46","AP01SDTM":"2020-08-30 08:45:46","AP01EDTM":"2022-08-30 20:45:46","AP02SDTM":"2022-08-30 20:45:46","AP02EDTM":"2023-08-31 02:45:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-31","EOSDY":1096,"LSTALVDT":"2023-09-21","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6160,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.12213,"AVALU":"U/L","BASE2":33.12213,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-25 08:45:46","ADY":148,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-13-id-177","SUBJID":"id-177","SITEID":"BRA-13","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-13","INVNAM":"Dr. BRA-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":12.71923,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-27","TRTSDTM":"2020-08-30 08:45:46","TRTEDTM":"2023-08-31 02:45:46","TRT01SDTM":"2020-08-30 08:45:46","TRT01EDTM":"2022-08-30 20:45:46","TRT02SDTM":"2022-08-30 20:45:46","TRT02EDTM":"2023-08-31 02:45:46","AP01SDTM":"2020-08-30 08:45:46","AP01EDTM":"2022-08-30 20:45:46","AP02SDTM":"2022-08-30 20:45:46","AP02EDTM":"2023-08-31 02:45:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-31","EOSDY":1096,"LSTALVDT":"2023-09-21","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2343,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.18026,"AVALU":"U/L","BASE2":33.12213,"BASE":16.18026,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-16.94187,"PCHG2":-51.14971,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-22 08:45:46","ADY":235,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-13-id-177","SUBJID":"id-177","SITEID":"BRA-13","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-13","INVNAM":"Dr. BRA-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":12.71923,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-27","TRTSDTM":"2020-08-30 08:45:46","TRTEDTM":"2023-08-31 02:45:46","TRT01SDTM":"2020-08-30 08:45:46","TRT01EDTM":"2022-08-30 20:45:46","TRT02SDTM":"2022-08-30 20:45:46","TRT02EDTM":"2023-08-31 02:45:46","AP01SDTM":"2020-08-30 08:45:46","AP01EDTM":"2022-08-30 20:45:46","AP02SDTM":"2022-08-30 20:45:46","AP02EDTM":"2023-08-31 02:45:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-31","EOSDY":1096,"LSTALVDT":"2023-09-21","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7479,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.30154,"AVALU":"U/L","BASE2":33.12213,"BASE":16.18026,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-18.82059,"PCHG2":-56.8218,"CHG":-1.87872,"PCHG":-11.61117,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-26 08:45:46","ADY":392,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-13-id-177","SUBJID":"id-177","SITEID":"BRA-13","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-13","INVNAM":"Dr. BRA-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":12.71923,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-27","TRTSDTM":"2020-08-30 08:45:46","TRTEDTM":"2023-08-31 02:45:46","TRT01SDTM":"2020-08-30 08:45:46","TRT01EDTM":"2022-08-30 20:45:46","TRT02SDTM":"2022-08-30 20:45:46","TRT02EDTM":"2023-08-31 02:45:46","AP01SDTM":"2020-08-30 08:45:46","AP01EDTM":"2022-08-30 20:45:46","AP02SDTM":"2022-08-30 20:45:46","AP02EDTM":"2023-08-31 02:45:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-31","EOSDY":1096,"LSTALVDT":"2023-09-21","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5838,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.89962,"AVALU":"U/L","BASE2":33.12213,"BASE":16.18026,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.2225,"PCHG2":-12.74828,"CHG":12.71937,"PCHG":78.61043,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-27 08:45:46","ADY":605,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-13-id-177","SUBJID":"id-177","SITEID":"BRA-13","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-13","INVNAM":"Dr. BRA-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":12.71923,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-27","TRTSDTM":"2020-08-30 08:45:46","TRTEDTM":"2023-08-31 02:45:46","TRT01SDTM":"2020-08-30 08:45:46","TRT01EDTM":"2022-08-30 20:45:46","TRT02SDTM":"2022-08-30 20:45:46","TRT02EDTM":"2023-08-31 02:45:46","AP01SDTM":"2020-08-30 08:45:46","AP01EDTM":"2022-08-30 20:45:46","AP02SDTM":"2022-08-30 20:45:46","AP02EDTM":"2023-08-31 02:45:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-31","EOSDY":1096,"LSTALVDT":"2023-09-21","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3164,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.02914,"AVALU":"U/L","BASE2":33.12213,"BASE":16.18026,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.09299,"PCHG2":-15.3764,"CHG":11.84888,"PCHG":73.23049,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-25 08:45:46","ADY":633,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-13-id-177","SUBJID":"id-177","SITEID":"BRA-13","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-13","INVNAM":"Dr. BRA-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":12.71923,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-27","TRTSDTM":"2020-08-30 08:45:46","TRTEDTM":"2023-08-31 02:45:46","TRT01SDTM":"2020-08-30 08:45:46","TRT01EDTM":"2022-08-30 20:45:46","TRT02SDTM":"2022-08-30 20:45:46","TRT02EDTM":"2023-08-31 02:45:46","AP01SDTM":"2020-08-30 08:45:46","AP01EDTM":"2022-08-30 20:45:46","AP02SDTM":"2022-08-30 20:45:46","AP02EDTM":"2023-08-31 02:45:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-31","EOSDY":1096,"LSTALVDT":"2023-09-21","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3762,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.0889,"AVALU":"U/L","BASE2":33.12213,"BASE":16.18026,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.03322,"PCHG2":-12.17682,"CHG":12.90865,"PCHG":79.78024,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-20 08:45:46","ADY":720,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-13-id-177","SUBJID":"id-177","SITEID":"BRA-13","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-13","INVNAM":"Dr. BRA-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":12.71923,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-27","TRTSDTM":"2020-08-30 08:45:46","TRTEDTM":"2023-08-31 02:45:46","TRT01SDTM":"2020-08-30 08:45:46","TRT01EDTM":"2022-08-30 20:45:46","TRT02SDTM":"2022-08-30 20:45:46","TRT02EDTM":"2023-08-31 02:45:46","AP01SDTM":"2020-08-30 08:45:46","AP01EDTM":"2022-08-30 20:45:46","AP02SDTM":"2022-08-30 20:45:46","AP02EDTM":"2023-08-31 02:45:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-31","EOSDY":1096,"LSTALVDT":"2023-09-21","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5724,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.69025,"AVALU":"U/L","BASE2":33.12213,"BASE":16.18026,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-25.43187,"PCHG2":-76.78213,"CHG":-8.49,"PCHG":-52.47138,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-09 08:45:46","ADY":801,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-13-id-177","SUBJID":"id-177","SITEID":"BRA-13","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-13","INVNAM":"Dr. BRA-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":12.71923,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-27","TRTSDTM":"2020-08-30 08:45:46","TRTEDTM":"2023-08-31 02:45:46","TRT01SDTM":"2020-08-30 08:45:46","TRT01EDTM":"2022-08-30 20:45:46","TRT02SDTM":"2022-08-30 20:45:46","TRT02EDTM":"2023-08-31 02:45:46","AP01SDTM":"2020-08-30 08:45:46","AP01EDTM":"2022-08-30 20:45:46","AP02SDTM":"2022-08-30 20:45:46","AP02EDTM":"2023-08-31 02:45:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-31","EOSDY":1096,"LSTALVDT":"2023-09-21","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4574,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.52377,"AVALU":"mg/L","BASE2":9.52377,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-25 08:45:46","ADY":148,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-13-id-177","SUBJID":"id-177","SITEID":"BRA-13","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-13","INVNAM":"Dr. BRA-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":12.71923,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-27","TRTSDTM":"2020-08-30 08:45:46","TRTEDTM":"2023-08-31 02:45:46","TRT01SDTM":"2020-08-30 08:45:46","TRT01EDTM":"2022-08-30 20:45:46","TRT02SDTM":"2022-08-30 20:45:46","TRT02EDTM":"2023-08-31 02:45:46","AP01SDTM":"2020-08-30 08:45:46","AP01EDTM":"2022-08-30 20:45:46","AP02SDTM":"2022-08-30 20:45:46","AP02EDTM":"2023-08-31 02:45:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-31","EOSDY":1096,"LSTALVDT":"2023-09-21","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6880,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.41287,"AVALU":"mg/L","BASE2":9.52377,"BASE":9.41287,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.1109,"PCHG2":-1.16446,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-22 08:45:46","ADY":235,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-13-id-177","SUBJID":"id-177","SITEID":"BRA-13","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-13","INVNAM":"Dr. BRA-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":12.71923,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-27","TRTSDTM":"2020-08-30 08:45:46","TRTEDTM":"2023-08-31 02:45:46","TRT01SDTM":"2020-08-30 08:45:46","TRT01EDTM":"2022-08-30 20:45:46","TRT02SDTM":"2022-08-30 20:45:46","TRT02EDTM":"2023-08-31 02:45:46","AP01SDTM":"2020-08-30 08:45:46","AP01EDTM":"2022-08-30 20:45:46","AP02SDTM":"2022-08-30 20:45:46","AP02EDTM":"2023-08-31 02:45:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-31","EOSDY":1096,"LSTALVDT":"2023-09-21","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3794,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.3564,"AVALU":"mg/L","BASE2":9.52377,"BASE":9.41287,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16737,"PCHG2":-1.75743,"CHG":-0.05647,"PCHG":-0.59996,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-26 08:45:46","ADY":392,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-13-id-177","SUBJID":"id-177","SITEID":"BRA-13","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-13","INVNAM":"Dr. BRA-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":12.71923,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-27","TRTSDTM":"2020-08-30 08:45:46","TRTEDTM":"2023-08-31 02:45:46","TRT01SDTM":"2020-08-30 08:45:46","TRT01EDTM":"2022-08-30 20:45:46","TRT02SDTM":"2022-08-30 20:45:46","TRT02EDTM":"2023-08-31 02:45:46","AP01SDTM":"2020-08-30 08:45:46","AP01EDTM":"2022-08-30 20:45:46","AP02SDTM":"2022-08-30 20:45:46","AP02EDTM":"2023-08-31 02:45:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-31","EOSDY":1096,"LSTALVDT":"2023-09-21","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1809,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.88128,"AVALU":"mg/L","BASE2":9.52377,"BASE":9.41287,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.3575,"PCHG2":3.7538,"CHG":0.4684,"PCHG":4.97621,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-27 08:45:46","ADY":605,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-13-id-177","SUBJID":"id-177","SITEID":"BRA-13","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-13","INVNAM":"Dr. BRA-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":12.71923,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-27","TRTSDTM":"2020-08-30 08:45:46","TRTEDTM":"2023-08-31 02:45:46","TRT01SDTM":"2020-08-30 08:45:46","TRT01EDTM":"2022-08-30 20:45:46","TRT02SDTM":"2022-08-30 20:45:46","TRT02EDTM":"2023-08-31 02:45:46","AP01SDTM":"2020-08-30 08:45:46","AP01EDTM":"2022-08-30 20:45:46","AP02SDTM":"2022-08-30 20:45:46","AP02EDTM":"2023-08-31 02:45:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-31","EOSDY":1096,"LSTALVDT":"2023-09-21","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7370,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.1076,"AVALU":"mg/L","BASE2":9.52377,"BASE":9.41287,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.41617,"PCHG2":-4.36985,"CHG":-0.30527,"PCHG":-3.24315,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-25 08:45:46","ADY":633,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-13-id-177","SUBJID":"id-177","SITEID":"BRA-13","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-13","INVNAM":"Dr. BRA-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":12.71923,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-27","TRTSDTM":"2020-08-30 08:45:46","TRTEDTM":"2023-08-31 02:45:46","TRT01SDTM":"2020-08-30 08:45:46","TRT01EDTM":"2022-08-30 20:45:46","TRT02SDTM":"2022-08-30 20:45:46","TRT02EDTM":"2023-08-31 02:45:46","AP01SDTM":"2020-08-30 08:45:46","AP01EDTM":"2022-08-30 20:45:46","AP02SDTM":"2022-08-30 20:45:46","AP02EDTM":"2023-08-31 02:45:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-31","EOSDY":1096,"LSTALVDT":"2023-09-21","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2254,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.80206,"AVALU":"mg/L","BASE2":9.52377,"BASE":9.41287,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.72171,"PCHG2":-7.57802,"CHG":-0.61081,"PCHG":-6.48912,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-20 08:45:46","ADY":720,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-13-id-177","SUBJID":"id-177","SITEID":"BRA-13","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-13","INVNAM":"Dr. BRA-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":12.71923,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-27","TRTSDTM":"2020-08-30 08:45:46","TRTEDTM":"2023-08-31 02:45:46","TRT01SDTM":"2020-08-30 08:45:46","TRT01EDTM":"2022-08-30 20:45:46","TRT02SDTM":"2022-08-30 20:45:46","TRT02EDTM":"2023-08-31 02:45:46","AP01SDTM":"2020-08-30 08:45:46","AP01EDTM":"2022-08-30 20:45:46","AP02SDTM":"2022-08-30 20:45:46","AP02EDTM":"2023-08-31 02:45:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-31","EOSDY":1096,"LSTALVDT":"2023-09-21","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1206,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.17343,"AVALU":"mg/L","BASE2":9.52377,"BASE":9.41287,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.35035,"PCHG2":-3.67865,"CHG":-0.23945,"PCHG":-2.54381,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-09 08:45:46","ADY":801,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-13-id-177","SUBJID":"id-177","SITEID":"BRA-13","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-13","INVNAM":"Dr. BRA-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":12.71923,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-27","TRTSDTM":"2020-08-30 08:45:46","TRTEDTM":"2023-08-31 02:45:46","TRT01SDTM":"2020-08-30 08:45:46","TRT01EDTM":"2022-08-30 20:45:46","TRT02SDTM":"2022-08-30 20:45:46","TRT02EDTM":"2023-08-31 02:45:46","AP01SDTM":"2020-08-30 08:45:46","AP01EDTM":"2022-08-30 20:45:46","AP02SDTM":"2022-08-30 20:45:46","AP02EDTM":"2023-08-31 02:45:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-31","EOSDY":1096,"LSTALVDT":"2023-09-21","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4773,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89216,"AVALU":"g/L","BASE2":2.89216,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-01-25 08:45:46","ADY":148,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-13-id-177","SUBJID":"id-177","SITEID":"BRA-13","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-13","INVNAM":"Dr. BRA-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":12.71923,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-27","TRTSDTM":"2020-08-30 08:45:46","TRTEDTM":"2023-08-31 02:45:46","TRT01SDTM":"2020-08-30 08:45:46","TRT01EDTM":"2022-08-30 20:45:46","TRT02SDTM":"2022-08-30 20:45:46","TRT02EDTM":"2023-08-31 02:45:46","AP01SDTM":"2020-08-30 08:45:46","AP01EDTM":"2022-08-30 20:45:46","AP02SDTM":"2022-08-30 20:45:46","AP02EDTM":"2023-08-31 02:45:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-31","EOSDY":1096,"LSTALVDT":"2023-09-21","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6212,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0886,"AVALU":"g/L","BASE2":2.89216,"BASE":3.0886,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.19644,"PCHG2":6.79232,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2021-04-22 08:45:46","ADY":235,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-13-id-177","SUBJID":"id-177","SITEID":"BRA-13","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-13","INVNAM":"Dr. BRA-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":12.71923,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-27","TRTSDTM":"2020-08-30 08:45:46","TRTEDTM":"2023-08-31 02:45:46","TRT01SDTM":"2020-08-30 08:45:46","TRT01EDTM":"2022-08-30 20:45:46","TRT02SDTM":"2022-08-30 20:45:46","TRT02EDTM":"2023-08-31 02:45:46","AP01SDTM":"2020-08-30 08:45:46","AP01EDTM":"2022-08-30 20:45:46","AP02SDTM":"2022-08-30 20:45:46","AP02EDTM":"2023-08-31 02:45:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-31","EOSDY":1096,"LSTALVDT":"2023-09-21","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2133,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84193,"AVALU":"g/L","BASE2":2.89216,"BASE":3.0886,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05023,"PCHG2":-1.73667,"CHG":-0.24667,"PCHG":-7.98652,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-09-26 08:45:46","ADY":392,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-13-id-177","SUBJID":"id-177","SITEID":"BRA-13","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-13","INVNAM":"Dr. BRA-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":12.71923,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-27","TRTSDTM":"2020-08-30 08:45:46","TRTEDTM":"2023-08-31 02:45:46","TRT01SDTM":"2020-08-30 08:45:46","TRT01EDTM":"2022-08-30 20:45:46","TRT02SDTM":"2022-08-30 20:45:46","TRT02EDTM":"2023-08-31 02:45:46","AP01SDTM":"2020-08-30 08:45:46","AP01EDTM":"2022-08-30 20:45:46","AP02SDTM":"2022-08-30 20:45:46","AP02EDTM":"2023-08-31 02:45:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-31","EOSDY":1096,"LSTALVDT":"2023-09-21","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4938,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80953,"AVALU":"g/L","BASE2":2.89216,"BASE":3.0886,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08262,"PCHG2":-2.85672,"CHG":-0.27907,"PCHG":-9.03533,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-04-27 08:45:46","ADY":605,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-13-id-177","SUBJID":"id-177","SITEID":"BRA-13","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-13","INVNAM":"Dr. BRA-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":12.71923,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-27","TRTSDTM":"2020-08-30 08:45:46","TRTEDTM":"2023-08-31 02:45:46","TRT01SDTM":"2020-08-30 08:45:46","TRT01EDTM":"2022-08-30 20:45:46","TRT02SDTM":"2022-08-30 20:45:46","TRT02EDTM":"2023-08-31 02:45:46","AP01SDTM":"2020-08-30 08:45:46","AP01EDTM":"2022-08-30 20:45:46","AP02SDTM":"2022-08-30 20:45:46","AP02EDTM":"2023-08-31 02:45:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-31","EOSDY":1096,"LSTALVDT":"2023-09-21","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7454,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88937,"AVALU":"g/L","BASE2":2.89216,"BASE":3.0886,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00278,"PCHG2":-0.09617,"CHG":-0.19923,"PCHG":-6.45036,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-05-25 08:45:46","ADY":633,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-13-id-177","SUBJID":"id-177","SITEID":"BRA-13","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-13","INVNAM":"Dr. BRA-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":12.71923,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-27","TRTSDTM":"2020-08-30 08:45:46","TRTEDTM":"2023-08-31 02:45:46","TRT01SDTM":"2020-08-30 08:45:46","TRT01EDTM":"2022-08-30 20:45:46","TRT02SDTM":"2022-08-30 20:45:46","TRT02EDTM":"2023-08-31 02:45:46","AP01SDTM":"2020-08-30 08:45:46","AP01EDTM":"2022-08-30 20:45:46","AP02SDTM":"2022-08-30 20:45:46","AP02EDTM":"2023-08-31 02:45:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-31","EOSDY":1096,"LSTALVDT":"2023-09-21","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":796,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86234,"AVALU":"g/L","BASE2":2.89216,"BASE":3.0886,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02982,"PCHG2":-1.03096,"CHG":-0.22626,"PCHG":-7.3257,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-08-20 08:45:46","ADY":720,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-13-id-177","SUBJID":"id-177","SITEID":"BRA-13","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-13","INVNAM":"Dr. BRA-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":12.71923,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-27","TRTSDTM":"2020-08-30 08:45:46","TRTEDTM":"2023-08-31 02:45:46","TRT01SDTM":"2020-08-30 08:45:46","TRT01EDTM":"2022-08-30 20:45:46","TRT02SDTM":"2022-08-30 20:45:46","TRT02EDTM":"2023-08-31 02:45:46","AP01SDTM":"2020-08-30 08:45:46","AP01EDTM":"2022-08-30 20:45:46","AP02SDTM":"2022-08-30 20:45:46","AP02EDTM":"2023-08-31 02:45:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-31","EOSDY":1096,"LSTALVDT":"2023-09-21","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":152,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75528,"AVALU":"g/L","BASE2":2.89216,"BASE":3.0886,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13687,"PCHG2":-4.73261,"CHG":-0.33332,"PCHG":-10.79191,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-11-09 08:45:46","ADY":801,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-120","SUBJID":"id-120","SITEID":"BRA-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.93474,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-17","TRTSDTM":"2020-09-19 09:07:52","TRTEDTM":"2022-02-12 22:51:28","TRT01SDTM":"2020-09-19 09:07:52","TRT01EDTM":"2021-02-12 16:51:28","TRT02SDTM":"2021-02-12 16:51:28","TRT02EDTM":"2022-02-12 22:51:28","AP01SDTM":"2020-09-19 09:07:52","AP01EDTM":"2021-02-12 16:51:28","AP02SDTM":"2021-02-12 16:51:28","AP02EDTM":"2022-02-12 22:51:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":512,"DCSREAS":"DEATH","DTHDT":"2022-03-20","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-20","DTHADY":546,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1113,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.7899,"AVALU":"U/L","BASE2":16.7899,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-06 09:07:52","ADY":109,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-120","SUBJID":"id-120","SITEID":"BRA-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.93474,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-17","TRTSDTM":"2020-09-19 09:07:52","TRTEDTM":"2022-02-12 22:51:28","TRT01SDTM":"2020-09-19 09:07:52","TRT01EDTM":"2021-02-12 16:51:28","TRT02SDTM":"2021-02-12 16:51:28","TRT02EDTM":"2022-02-12 22:51:28","AP01SDTM":"2020-09-19 09:07:52","AP01EDTM":"2021-02-12 16:51:28","AP02SDTM":"2021-02-12 16:51:28","AP02EDTM":"2022-02-12 22:51:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":512,"DCSREAS":"DEATH","DTHDT":"2022-03-20","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-20","DTHADY":546,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6329,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.51283,"AVALU":"U/L","BASE2":16.7899,"BASE":27.51283,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":10.72293,"PCHG2":63.86537,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-14 09:07:52","ADY":148,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-120","SUBJID":"id-120","SITEID":"BRA-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.93474,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-17","TRTSDTM":"2020-09-19 09:07:52","TRTEDTM":"2022-02-12 22:51:28","TRT01SDTM":"2020-09-19 09:07:52","TRT01EDTM":"2021-02-12 16:51:28","TRT02SDTM":"2021-02-12 16:51:28","TRT02EDTM":"2022-02-12 22:51:28","AP01SDTM":"2020-09-19 09:07:52","AP01EDTM":"2021-02-12 16:51:28","AP02SDTM":"2021-02-12 16:51:28","AP02EDTM":"2022-02-12 22:51:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":512,"DCSREAS":"DEATH","DTHDT":"2022-03-20","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-20","DTHADY":546,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5734,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":36.46233,"AVALU":"U/L","BASE2":16.7899,"BASE":27.51283,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.67243,"PCHG2":117.16827,"CHG":8.9495,"PCHG":32.52847,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-15 09:07:52","ADY":177,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-120","SUBJID":"id-120","SITEID":"BRA-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.93474,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-17","TRTSDTM":"2020-09-19 09:07:52","TRTEDTM":"2022-02-12 22:51:28","TRT01SDTM":"2020-09-19 09:07:52","TRT01EDTM":"2021-02-12 16:51:28","TRT02SDTM":"2021-02-12 16:51:28","TRT02EDTM":"2022-02-12 22:51:28","AP01SDTM":"2020-09-19 09:07:52","AP01EDTM":"2021-02-12 16:51:28","AP02SDTM":"2021-02-12 16:51:28","AP02EDTM":"2022-02-12 22:51:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":512,"DCSREAS":"DEATH","DTHDT":"2022-03-20","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-20","DTHADY":546,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8288,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.48453,"AVALU":"U/L","BASE2":16.7899,"BASE":27.51283,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.30537,"PCHG2":-55.42241,"CHG":-20.0283,"PCHG":-72.79621,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-09 09:07:52","ADY":293,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-120","SUBJID":"id-120","SITEID":"BRA-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.93474,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-17","TRTSDTM":"2020-09-19 09:07:52","TRTEDTM":"2022-02-12 22:51:28","TRT01SDTM":"2020-09-19 09:07:52","TRT01EDTM":"2021-02-12 16:51:28","TRT02SDTM":"2021-02-12 16:51:28","TRT02EDTM":"2022-02-12 22:51:28","AP01SDTM":"2020-09-19 09:07:52","AP01EDTM":"2021-02-12 16:51:28","AP02SDTM":"2021-02-12 16:51:28","AP02EDTM":"2022-02-12 22:51:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":512,"DCSREAS":"DEATH","DTHDT":"2022-03-20","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-20","DTHADY":546,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2361,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.79759,"AVALU":"U/L","BASE2":16.7899,"BASE":27.51283,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.99231,"PCHG2":-29.73399,"CHG":-15.71524,"PCHG":-57.11967,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-17 09:07:52","ADY":363,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-120","SUBJID":"id-120","SITEID":"BRA-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.93474,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-17","TRTSDTM":"2020-09-19 09:07:52","TRTEDTM":"2022-02-12 22:51:28","TRT01SDTM":"2020-09-19 09:07:52","TRT01EDTM":"2021-02-12 16:51:28","TRT02SDTM":"2021-02-12 16:51:28","TRT02EDTM":"2022-02-12 22:51:28","AP01SDTM":"2020-09-19 09:07:52","AP01EDTM":"2021-02-12 16:51:28","AP02SDTM":"2021-02-12 16:51:28","AP02EDTM":"2022-02-12 22:51:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":512,"DCSREAS":"DEATH","DTHDT":"2022-03-20","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-20","DTHADY":546,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2876,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.14052,"AVALU":"U/L","BASE2":16.7899,"BASE":27.51283,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.35062,"PCHG2":25.91212,"CHG":-6.37231,"PCHG":-23.16124,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-30 09:07:52","ADY":437,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-120","SUBJID":"id-120","SITEID":"BRA-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.93474,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-17","TRTSDTM":"2020-09-19 09:07:52","TRTEDTM":"2022-02-12 22:51:28","TRT01SDTM":"2020-09-19 09:07:52","TRT01EDTM":"2021-02-12 16:51:28","TRT02SDTM":"2021-02-12 16:51:28","TRT02EDTM":"2022-02-12 22:51:28","AP01SDTM":"2020-09-19 09:07:52","AP01EDTM":"2021-02-12 16:51:28","AP02SDTM":"2021-02-12 16:51:28","AP02EDTM":"2022-02-12 22:51:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":512,"DCSREAS":"DEATH","DTHDT":"2022-03-20","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-20","DTHADY":546,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4628,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.65396,"AVALU":"U/L","BASE2":16.7899,"BASE":27.51283,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.86406,"PCHG2":58.74995,"CHG":-0.85887,"PCHG":-3.12172,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-12 09:07:52","ADY":449,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-120","SUBJID":"id-120","SITEID":"BRA-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.93474,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-17","TRTSDTM":"2020-09-19 09:07:52","TRTEDTM":"2022-02-12 22:51:28","TRT01SDTM":"2020-09-19 09:07:52","TRT01EDTM":"2021-02-12 16:51:28","TRT02SDTM":"2021-02-12 16:51:28","TRT02EDTM":"2022-02-12 22:51:28","AP01SDTM":"2020-09-19 09:07:52","AP01EDTM":"2021-02-12 16:51:28","AP02SDTM":"2021-02-12 16:51:28","AP02EDTM":"2022-02-12 22:51:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":512,"DCSREAS":"DEATH","DTHDT":"2022-03-20","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-20","DTHADY":546,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7794,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.16704,"AVALU":"mg/L","BASE2":9.16704,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-01-06 09:07:52","ADY":109,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-120","SUBJID":"id-120","SITEID":"BRA-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.93474,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-17","TRTSDTM":"2020-09-19 09:07:52","TRTEDTM":"2022-02-12 22:51:28","TRT01SDTM":"2020-09-19 09:07:52","TRT01EDTM":"2021-02-12 16:51:28","TRT02SDTM":"2021-02-12 16:51:28","TRT02EDTM":"2022-02-12 22:51:28","AP01SDTM":"2020-09-19 09:07:52","AP01EDTM":"2021-02-12 16:51:28","AP02SDTM":"2021-02-12 16:51:28","AP02EDTM":"2022-02-12 22:51:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":512,"DCSREAS":"DEATH","DTHDT":"2022-03-20","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-20","DTHADY":546,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4293,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.42927,"AVALU":"mg/L","BASE2":9.16704,"BASE":10.42927,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.26223,"PCHG2":13.76921,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2021-02-14 09:07:52","ADY":148,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-120","SUBJID":"id-120","SITEID":"BRA-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.93474,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-17","TRTSDTM":"2020-09-19 09:07:52","TRTEDTM":"2022-02-12 22:51:28","TRT01SDTM":"2020-09-19 09:07:52","TRT01EDTM":"2021-02-12 16:51:28","TRT02SDTM":"2021-02-12 16:51:28","TRT02EDTM":"2022-02-12 22:51:28","AP01SDTM":"2020-09-19 09:07:52","AP01EDTM":"2021-02-12 16:51:28","AP02SDTM":"2021-02-12 16:51:28","AP02EDTM":"2022-02-12 22:51:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":512,"DCSREAS":"DEATH","DTHDT":"2022-03-20","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-20","DTHADY":546,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7673,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.59905,"AVALU":"mg/L","BASE2":9.16704,"BASE":10.42927,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.56799,"PCHG2":-6.19596,"CHG":-1.83022,"PCHG":-17.54883,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-03-15 09:07:52","ADY":177,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-120","SUBJID":"id-120","SITEID":"BRA-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.93474,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-17","TRTSDTM":"2020-09-19 09:07:52","TRTEDTM":"2022-02-12 22:51:28","TRT01SDTM":"2020-09-19 09:07:52","TRT01EDTM":"2021-02-12 16:51:28","TRT02SDTM":"2021-02-12 16:51:28","TRT02EDTM":"2022-02-12 22:51:28","AP01SDTM":"2020-09-19 09:07:52","AP01EDTM":"2021-02-12 16:51:28","AP02SDTM":"2021-02-12 16:51:28","AP02EDTM":"2022-02-12 22:51:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":512,"DCSREAS":"DEATH","DTHDT":"2022-03-20","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-20","DTHADY":546,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4267,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.82775,"AVALU":"mg/L","BASE2":9.16704,"BASE":10.42927,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.66071,"PCHG2":18.11609,"CHG":0.39848,"PCHG":3.82078,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"1","BTOXGR":"2","ADTM":"2021-07-09 09:07:52","ADY":293,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-120","SUBJID":"id-120","SITEID":"BRA-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.93474,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-17","TRTSDTM":"2020-09-19 09:07:52","TRTEDTM":"2022-02-12 22:51:28","TRT01SDTM":"2020-09-19 09:07:52","TRT01EDTM":"2021-02-12 16:51:28","TRT02SDTM":"2021-02-12 16:51:28","TRT02EDTM":"2022-02-12 22:51:28","AP01SDTM":"2020-09-19 09:07:52","AP01EDTM":"2021-02-12 16:51:28","AP02SDTM":"2021-02-12 16:51:28","AP02EDTM":"2022-02-12 22:51:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":512,"DCSREAS":"DEATH","DTHDT":"2022-03-20","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-20","DTHADY":546,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1936,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.12983,"AVALU":"mg/L","BASE2":9.16704,"BASE":10.42927,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.96279,"PCHG2":10.50276,"CHG":-0.29944,"PCHG":-2.87112,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"1","BTOXGR":"2","ADTM":"2021-09-17 09:07:52","ADY":363,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-120","SUBJID":"id-120","SITEID":"BRA-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.93474,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-17","TRTSDTM":"2020-09-19 09:07:52","TRTEDTM":"2022-02-12 22:51:28","TRT01SDTM":"2020-09-19 09:07:52","TRT01EDTM":"2021-02-12 16:51:28","TRT02SDTM":"2021-02-12 16:51:28","TRT02EDTM":"2022-02-12 22:51:28","AP01SDTM":"2020-09-19 09:07:52","AP01EDTM":"2021-02-12 16:51:28","AP02SDTM":"2021-02-12 16:51:28","AP02EDTM":"2022-02-12 22:51:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":512,"DCSREAS":"DEATH","DTHDT":"2022-03-20","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-20","DTHADY":546,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6953,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.53962,"AVALU":"mg/L","BASE2":9.16704,"BASE":10.42927,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.37258,"PCHG2":25.88162,"CHG":1.11035,"PCHG":10.64648,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"1","BTOXGR":"2","ADTM":"2021-11-30 09:07:52","ADY":437,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-120","SUBJID":"id-120","SITEID":"BRA-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.93474,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-17","TRTSDTM":"2020-09-19 09:07:52","TRTEDTM":"2022-02-12 22:51:28","TRT01SDTM":"2020-09-19 09:07:52","TRT01EDTM":"2021-02-12 16:51:28","TRT02SDTM":"2021-02-12 16:51:28","TRT02EDTM":"2022-02-12 22:51:28","AP01SDTM":"2020-09-19 09:07:52","AP01EDTM":"2021-02-12 16:51:28","AP02SDTM":"2021-02-12 16:51:28","AP02EDTM":"2022-02-12 22:51:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":512,"DCSREAS":"DEATH","DTHDT":"2022-03-20","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-20","DTHADY":546,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3284,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.30127,"AVALU":"mg/L","BASE2":9.16704,"BASE":10.42927,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13423,"PCHG2":1.4643,"CHG":-1.128,"PCHG":-10.81567,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-12-12 09:07:52","ADY":449,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-120","SUBJID":"id-120","SITEID":"BRA-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.93474,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-17","TRTSDTM":"2020-09-19 09:07:52","TRTEDTM":"2022-02-12 22:51:28","TRT01SDTM":"2020-09-19 09:07:52","TRT01EDTM":"2021-02-12 16:51:28","TRT02SDTM":"2021-02-12 16:51:28","TRT02EDTM":"2022-02-12 22:51:28","AP01SDTM":"2020-09-19 09:07:52","AP01EDTM":"2021-02-12 16:51:28","AP02SDTM":"2021-02-12 16:51:28","AP02EDTM":"2022-02-12 22:51:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":512,"DCSREAS":"DEATH","DTHDT":"2022-03-20","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-20","DTHADY":546,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4682,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92864,"AVALU":"g/L","BASE2":2.92864,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-06 09:07:52","ADY":109,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-120","SUBJID":"id-120","SITEID":"BRA-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.93474,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-17","TRTSDTM":"2020-09-19 09:07:52","TRTEDTM":"2022-02-12 22:51:28","TRT01SDTM":"2020-09-19 09:07:52","TRT01EDTM":"2021-02-12 16:51:28","TRT02SDTM":"2021-02-12 16:51:28","TRT02EDTM":"2022-02-12 22:51:28","AP01SDTM":"2020-09-19 09:07:52","AP01EDTM":"2021-02-12 16:51:28","AP02SDTM":"2021-02-12 16:51:28","AP02EDTM":"2022-02-12 22:51:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":512,"DCSREAS":"DEATH","DTHDT":"2022-03-20","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-20","DTHADY":546,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5907,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76719,"AVALU":"g/L","BASE2":2.92864,"BASE":2.76719,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.16145,"PCHG2":-5.51276,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-14 09:07:52","ADY":148,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-120","SUBJID":"id-120","SITEID":"BRA-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.93474,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-17","TRTSDTM":"2020-09-19 09:07:52","TRTEDTM":"2022-02-12 22:51:28","TRT01SDTM":"2020-09-19 09:07:52","TRT01EDTM":"2021-02-12 16:51:28","TRT02SDTM":"2021-02-12 16:51:28","TRT02EDTM":"2022-02-12 22:51:28","AP01SDTM":"2020-09-19 09:07:52","AP01EDTM":"2021-02-12 16:51:28","AP02SDTM":"2021-02-12 16:51:28","AP02EDTM":"2022-02-12 22:51:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":512,"DCSREAS":"DEATH","DTHDT":"2022-03-20","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-20","DTHADY":546,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3597,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83902,"AVALU":"g/L","BASE2":2.92864,"BASE":2.76719,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08962,"PCHG2":-3.06015,"CHG":0.07183,"PCHG":2.5957,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-15 09:07:52","ADY":177,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-120","SUBJID":"id-120","SITEID":"BRA-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.93474,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-17","TRTSDTM":"2020-09-19 09:07:52","TRTEDTM":"2022-02-12 22:51:28","TRT01SDTM":"2020-09-19 09:07:52","TRT01EDTM":"2021-02-12 16:51:28","TRT02SDTM":"2021-02-12 16:51:28","TRT02EDTM":"2022-02-12 22:51:28","AP01SDTM":"2020-09-19 09:07:52","AP01EDTM":"2021-02-12 16:51:28","AP02SDTM":"2021-02-12 16:51:28","AP02EDTM":"2022-02-12 22:51:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":512,"DCSREAS":"DEATH","DTHDT":"2022-03-20","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-20","DTHADY":546,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6744,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93995,"AVALU":"g/L","BASE2":2.92864,"BASE":2.76719,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01131,"PCHG2":0.38607,"CHG":0.17276,"PCHG":6.24299,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-09 09:07:52","ADY":293,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-120","SUBJID":"id-120","SITEID":"BRA-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.93474,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-17","TRTSDTM":"2020-09-19 09:07:52","TRTEDTM":"2022-02-12 22:51:28","TRT01SDTM":"2020-09-19 09:07:52","TRT01EDTM":"2021-02-12 16:51:28","TRT02SDTM":"2021-02-12 16:51:28","TRT02EDTM":"2022-02-12 22:51:28","AP01SDTM":"2020-09-19 09:07:52","AP01EDTM":"2021-02-12 16:51:28","AP02SDTM":"2021-02-12 16:51:28","AP02EDTM":"2022-02-12 22:51:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":512,"DCSREAS":"DEATH","DTHDT":"2022-03-20","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-20","DTHADY":546,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2052,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.06543,"AVALU":"g/L","BASE2":2.92864,"BASE":2.76719,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13679,"PCHG2":4.67075,"CHG":0.29824,"PCHG":10.77765,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-09-17 09:07:52","ADY":363,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-120","SUBJID":"id-120","SITEID":"BRA-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.93474,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-17","TRTSDTM":"2020-09-19 09:07:52","TRTEDTM":"2022-02-12 22:51:28","TRT01SDTM":"2020-09-19 09:07:52","TRT01EDTM":"2021-02-12 16:51:28","TRT02SDTM":"2021-02-12 16:51:28","TRT02EDTM":"2022-02-12 22:51:28","AP01SDTM":"2020-09-19 09:07:52","AP01EDTM":"2021-02-12 16:51:28","AP02SDTM":"2021-02-12 16:51:28","AP02EDTM":"2022-02-12 22:51:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":512,"DCSREAS":"DEATH","DTHDT":"2022-03-20","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-20","DTHADY":546,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6168,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04255,"AVALU":"g/L","BASE2":2.92864,"BASE":2.76719,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11391,"PCHG2":3.8896,"CHG":0.27536,"PCHG":9.95093,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-11-30 09:07:52","ADY":437,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-120","SUBJID":"id-120","SITEID":"BRA-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.93474,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-17","TRTSDTM":"2020-09-19 09:07:52","TRTEDTM":"2022-02-12 22:51:28","TRT01SDTM":"2020-09-19 09:07:52","TRT01EDTM":"2021-02-12 16:51:28","TRT02SDTM":"2021-02-12 16:51:28","TRT02EDTM":"2022-02-12 22:51:28","AP01SDTM":"2020-09-19 09:07:52","AP01EDTM":"2021-02-12 16:51:28","AP02SDTM":"2021-02-12 16:51:28","AP02EDTM":"2022-02-12 22:51:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":512,"DCSREAS":"DEATH","DTHDT":"2022-03-20","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":36,"LDDTHGR1":">30","LSTALVDT":"2022-03-20","DTHADY":546,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5997,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91093,"AVALU":"g/L","BASE2":2.92864,"BASE":2.76719,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01771,"PCHG2":-0.60474,"CHG":0.14374,"PCHG":5.19437,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-12 09:07:52","ADY":449,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-23","SUBJID":"id-23","SITEID":"BRA-14","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.20239,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-06 10:33:42","TRT01SDTM":"2019-11-06 10:33:42","AP01SDTM":"2019-11-06 10:33:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6706,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.06558,"AVALU":"U/L","BASE2":21.06558,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-25 10:33:42","ADY":49,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-23","SUBJID":"id-23","SITEID":"BRA-14","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.20239,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-06 10:33:42","TRT01SDTM":"2019-11-06 10:33:42","AP01SDTM":"2019-11-06 10:33:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6930,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.89258,"AVALU":"U/L","BASE2":21.06558,"BASE":13.89258,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-7.173,"PCHG2":-34.05081,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-01 10:33:42","ADY":238,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-23","SUBJID":"id-23","SITEID":"BRA-14","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.20239,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-06 10:33:42","TRT01SDTM":"2019-11-06 10:33:42","AP01SDTM":"2019-11-06 10:33:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5367,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.05547,"AVALU":"U/L","BASE2":21.06558,"BASE":13.89258,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.98989,"PCHG2":23.6874,"CHG":12.16289,"PCHG":87.54955,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-16 10:33:42","ADY":315,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-23","SUBJID":"id-23","SITEID":"BRA-14","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.20239,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-06 10:33:42","TRT01SDTM":"2019-11-06 10:33:42","AP01SDTM":"2019-11-06 10:33:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2113,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.91448,"AVALU":"U/L","BASE2":21.06558,"BASE":13.89258,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.1511,"PCHG2":-43.44099,"CHG":-1.97809,"PCHG":-14.2385,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-29 10:33:42","ADY":540,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-23","SUBJID":"id-23","SITEID":"BRA-14","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.20239,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-06 10:33:42","TRT01SDTM":"2019-11-06 10:33:42","AP01SDTM":"2019-11-06 10:33:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6682,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.59343,"AVALU":"U/L","BASE2":21.06558,"BASE":13.89258,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-20.47215,"PCHG2":-97.18295,"CHG":-13.29915,"PCHG":-95.72845,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-06-22 10:33:42","ADY":594,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-23","SUBJID":"id-23","SITEID":"BRA-14","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.20239,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-06 10:33:42","TRT01SDTM":"2019-11-06 10:33:42","AP01SDTM":"2019-11-06 10:33:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6877,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.37712,"AVALU":"U/L","BASE2":21.06558,"BASE":13.89258,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.68846,"PCHG2":-8.01526,"CHG":5.48454,"PCHG":39.4782,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-16 10:33:42","ADY":680,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-23","SUBJID":"id-23","SITEID":"BRA-14","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.20239,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-06 10:33:42","TRT01SDTM":"2019-11-06 10:33:42","AP01SDTM":"2019-11-06 10:33:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6006,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.07715,"AVALU":"U/L","BASE2":21.06558,"BASE":13.89258,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.98842,"PCHG2":-18.93337,"CHG":3.18458,"PCHG":22.92286,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-01 10:33:42","ADY":726,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-23","SUBJID":"id-23","SITEID":"BRA-14","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.20239,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-06 10:33:42","TRT01SDTM":"2019-11-06 10:33:42","AP01SDTM":"2019-11-06 10:33:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2501,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.54108,"AVALU":"mg/L","BASE2":9.54108,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-25 10:33:42","ADY":49,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-23","SUBJID":"id-23","SITEID":"BRA-14","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.20239,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-06 10:33:42","TRT01SDTM":"2019-11-06 10:33:42","AP01SDTM":"2019-11-06 10:33:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7694,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.63385,"AVALU":"mg/L","BASE2":9.54108,"BASE":8.63385,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.90722,"PCHG2":-9.5086,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-01 10:33:42","ADY":238,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-23","SUBJID":"id-23","SITEID":"BRA-14","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.20239,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-06 10:33:42","TRT01SDTM":"2019-11-06 10:33:42","AP01SDTM":"2019-11-06 10:33:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4217,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.31276,"AVALU":"mg/L","BASE2":9.54108,"BASE":8.63385,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.22832,"PCHG2":-23.35497,"CHG":-1.32109,"PCHG":-15.30131,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-09-16 10:33:42","ADY":315,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-23","SUBJID":"id-23","SITEID":"BRA-14","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.20239,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-06 10:33:42","TRT01SDTM":"2019-11-06 10:33:42","AP01SDTM":"2019-11-06 10:33:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":338,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.76034,"AVALU":"mg/L","BASE2":9.54108,"BASE":8.63385,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.21926,"PCHG2":2.29809,"CHG":1.12648,"PCHG":13.0473,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-29 10:33:42","ADY":540,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-23","SUBJID":"id-23","SITEID":"BRA-14","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.20239,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-06 10:33:42","TRT01SDTM":"2019-11-06 10:33:42","AP01SDTM":"2019-11-06 10:33:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":417,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.41736,"AVALU":"mg/L","BASE2":9.54108,"BASE":8.63385,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.12371,"PCHG2":-11.77764,"CHG":-0.21649,"PCHG":-2.50747,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-22 10:33:42","ADY":594,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-23","SUBJID":"id-23","SITEID":"BRA-14","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.20239,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-06 10:33:42","TRT01SDTM":"2019-11-06 10:33:42","AP01SDTM":"2019-11-06 10:33:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6759,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.2464,"AVALU":"mg/L","BASE2":9.54108,"BASE":8.63385,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.70532,"PCHG2":7.39246,"CHG":1.61254,"PCHG":18.67698,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-09-16 10:33:42","ADY":680,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-23","SUBJID":"id-23","SITEID":"BRA-14","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.20239,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-06 10:33:42","TRT01SDTM":"2019-11-06 10:33:42","AP01SDTM":"2019-11-06 10:33:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5022,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.88007,"AVALU":"mg/L","BASE2":9.54108,"BASE":8.63385,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.66101,"PCHG2":-6.928,"CHG":0.24622,"PCHG":2.85176,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-01 10:33:42","ADY":726,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-23","SUBJID":"id-23","SITEID":"BRA-14","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.20239,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-06 10:33:42","TRT01SDTM":"2019-11-06 10:33:42","AP01SDTM":"2019-11-06 10:33:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7708,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96046,"AVALU":"g/L","BASE2":2.96046,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-25 10:33:42","ADY":49,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-23","SUBJID":"id-23","SITEID":"BRA-14","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.20239,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-06 10:33:42","TRT01SDTM":"2019-11-06 10:33:42","AP01SDTM":"2019-11-06 10:33:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7783,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.704,"AVALU":"g/L","BASE2":2.96046,"BASE":2.704,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.25646,"PCHG2":-8.66291,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-01 10:33:42","ADY":238,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-23","SUBJID":"id-23","SITEID":"BRA-14","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.20239,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-06 10:33:42","TRT01SDTM":"2019-11-06 10:33:42","AP01SDTM":"2019-11-06 10:33:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5610,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04898,"AVALU":"g/L","BASE2":2.96046,"BASE":2.704,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08853,"PCHG2":2.99031,"CHG":0.34499,"PCHG":12.75847,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-09-16 10:33:42","ADY":315,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-23","SUBJID":"id-23","SITEID":"BRA-14","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.20239,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-06 10:33:42","TRT01SDTM":"2019-11-06 10:33:42","AP01SDTM":"2019-11-06 10:33:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2742,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02826,"AVALU":"g/L","BASE2":2.96046,"BASE":2.704,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0678,"PCHG2":2.29018,"CHG":0.32426,"PCHG":11.99194,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-04-29 10:33:42","ADY":540,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-23","SUBJID":"id-23","SITEID":"BRA-14","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.20239,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-06 10:33:42","TRT01SDTM":"2019-11-06 10:33:42","AP01SDTM":"2019-11-06 10:33:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4050,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85538,"AVALU":"g/L","BASE2":2.96046,"BASE":2.704,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10508,"PCHG2":-3.54945,"CHG":0.15138,"PCHG":5.59845,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-22 10:33:42","ADY":594,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-23","SUBJID":"id-23","SITEID":"BRA-14","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.20239,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-06 10:33:42","TRT01SDTM":"2019-11-06 10:33:42","AP01SDTM":"2019-11-06 10:33:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7820,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01961,"AVALU":"g/L","BASE2":2.96046,"BASE":2.704,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05915,"PCHG2":1.99793,"CHG":0.31561,"PCHG":11.67197,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2021-09-16 10:33:42","ADY":680,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-14-id-23","SUBJID":"id-23","SITEID":"BRA-14","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-14","INVNAM":"Dr. BRA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.20239,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-06 10:33:42","TRT01SDTM":"2019-11-06 10:33:42","AP01SDTM":"2019-11-06 10:33:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":688,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91343,"AVALU":"g/L","BASE2":2.96046,"BASE":2.704,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04703,"PCHG2":-1.58854,"CHG":0.20943,"PCHG":7.74535,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-01 10:33:42","ADY":726,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-15-id-36","SUBJID":"id-36","SITEID":"BRA-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-15","INVNAM":"Dr. BRA-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.40685,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 02:45:36","TRTEDTM":"2022-02-12 18:57:18","TRT01SDTM":"2020-01-08 02:45:36","TRT01EDTM":"2021-02-12 12:57:18","TRT02SDTM":"2021-02-12 12:57:18","TRT02EDTM":"2022-02-12 18:57:18","AP01SDTM":"2020-01-08 02:45:36","AP01EDTM":"2021-02-12 12:57:18","AP02SDTM":"2021-02-12 12:57:18","AP02EDTM":"2022-02-12 18:57:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":767,"DCSREAS":"DEATH","DTHDT":"2022-03-31","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-03-31","DTHADY":812,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4583,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.56999,"AVALU":"U/L","BASE2":22.56999,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-11 02:45:36","ADY":63,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-15-id-36","SUBJID":"id-36","SITEID":"BRA-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-15","INVNAM":"Dr. BRA-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.40685,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 02:45:36","TRTEDTM":"2022-02-12 18:57:18","TRT01SDTM":"2020-01-08 02:45:36","TRT01EDTM":"2021-02-12 12:57:18","TRT02SDTM":"2021-02-12 12:57:18","TRT02EDTM":"2022-02-12 18:57:18","AP01SDTM":"2020-01-08 02:45:36","AP01EDTM":"2021-02-12 12:57:18","AP02SDTM":"2021-02-12 12:57:18","AP02EDTM":"2022-02-12 18:57:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":767,"DCSREAS":"DEATH","DTHDT":"2022-03-31","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-03-31","DTHADY":812,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5754,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.67668,"AVALU":"U/L","BASE2":22.56999,"BASE":26.67668,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":4.10669,"PCHG2":18.19535,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-14 02:45:36","ADY":97,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-15-id-36","SUBJID":"id-36","SITEID":"BRA-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-15","INVNAM":"Dr. BRA-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.40685,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 02:45:36","TRTEDTM":"2022-02-12 18:57:18","TRT01SDTM":"2020-01-08 02:45:36","TRT01EDTM":"2021-02-12 12:57:18","TRT02SDTM":"2021-02-12 12:57:18","TRT02EDTM":"2022-02-12 18:57:18","AP01SDTM":"2020-01-08 02:45:36","AP01EDTM":"2021-02-12 12:57:18","AP02SDTM":"2021-02-12 12:57:18","AP02EDTM":"2022-02-12 18:57:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":767,"DCSREAS":"DEATH","DTHDT":"2022-03-31","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-03-31","DTHADY":812,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8150,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.09864,"AVALU":"U/L","BASE2":22.56999,"BASE":26.67668,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.47134,"PCHG2":-24.24168,"CHG":-9.57803,"PCHG":-35.90414,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-15 02:45:36","ADY":220,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-15-id-36","SUBJID":"id-36","SITEID":"BRA-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-15","INVNAM":"Dr. BRA-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.40685,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 02:45:36","TRTEDTM":"2022-02-12 18:57:18","TRT01SDTM":"2020-01-08 02:45:36","TRT01EDTM":"2021-02-12 12:57:18","TRT02SDTM":"2021-02-12 12:57:18","TRT02EDTM":"2022-02-12 18:57:18","AP01SDTM":"2020-01-08 02:45:36","AP01EDTM":"2021-02-12 12:57:18","AP02SDTM":"2021-02-12 12:57:18","AP02EDTM":"2022-02-12 18:57:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":767,"DCSREAS":"DEATH","DTHDT":"2022-03-31","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-03-31","DTHADY":812,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4504,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.96536,"AVALU":"U/L","BASE2":22.56999,"BASE":26.67668,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.39537,"PCHG2":37.19707,"CHG":4.28869,"PCHG":16.07654,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-25 02:45:36","ADY":442,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-15-id-36","SUBJID":"id-36","SITEID":"BRA-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-15","INVNAM":"Dr. BRA-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.40685,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 02:45:36","TRTEDTM":"2022-02-12 18:57:18","TRT01SDTM":"2020-01-08 02:45:36","TRT01EDTM":"2021-02-12 12:57:18","TRT02SDTM":"2021-02-12 12:57:18","TRT02EDTM":"2022-02-12 18:57:18","AP01SDTM":"2020-01-08 02:45:36","AP01EDTM":"2021-02-12 12:57:18","AP02SDTM":"2021-02-12 12:57:18","AP02EDTM":"2022-02-12 18:57:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":767,"DCSREAS":"DEATH","DTHDT":"2022-03-31","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-03-31","DTHADY":812,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6169,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.71627,"AVALU":"U/L","BASE2":22.56999,"BASE":26.67668,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.85372,"PCHG2":-17.07454,"CHG":-7.96041,"PCHG":-29.84034,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-21 02:45:36","ADY":499,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-15-id-36","SUBJID":"id-36","SITEID":"BRA-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-15","INVNAM":"Dr. BRA-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.40685,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 02:45:36","TRTEDTM":"2022-02-12 18:57:18","TRT01SDTM":"2020-01-08 02:45:36","TRT01EDTM":"2021-02-12 12:57:18","TRT02SDTM":"2021-02-12 12:57:18","TRT02EDTM":"2022-02-12 18:57:18","AP01SDTM":"2020-01-08 02:45:36","AP01EDTM":"2021-02-12 12:57:18","AP02SDTM":"2021-02-12 12:57:18","AP02EDTM":"2022-02-12 18:57:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":767,"DCSREAS":"DEATH","DTHDT":"2022-03-31","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-03-31","DTHADY":812,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3471,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.78539,"AVALU":"U/L","BASE2":22.56999,"BASE":26.67668,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.2154,"PCHG2":45.26098,"CHG":6.10871,"PCHG":22.89906,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-26 02:45:36","ADY":504,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-15-id-36","SUBJID":"id-36","SITEID":"BRA-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-15","INVNAM":"Dr. BRA-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.40685,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 02:45:36","TRTEDTM":"2022-02-12 18:57:18","TRT01SDTM":"2020-01-08 02:45:36","TRT01EDTM":"2021-02-12 12:57:18","TRT02SDTM":"2021-02-12 12:57:18","TRT02EDTM":"2022-02-12 18:57:18","AP01SDTM":"2020-01-08 02:45:36","AP01EDTM":"2021-02-12 12:57:18","AP02SDTM":"2021-02-12 12:57:18","AP02EDTM":"2022-02-12 18:57:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":767,"DCSREAS":"DEATH","DTHDT":"2022-03-31","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-03-31","DTHADY":812,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5902,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.75845,"AVALU":"U/L","BASE2":22.56999,"BASE":26.67668,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.81154,"PCHG2":-43.47161,"CHG":-13.91823,"PCHG":-52.17376,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-23 02:45:36","ADY":654,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-15-id-36","SUBJID":"id-36","SITEID":"BRA-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-15","INVNAM":"Dr. BRA-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.40685,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 02:45:36","TRTEDTM":"2022-02-12 18:57:18","TRT01SDTM":"2020-01-08 02:45:36","TRT01EDTM":"2021-02-12 12:57:18","TRT02SDTM":"2021-02-12 12:57:18","TRT02EDTM":"2022-02-12 18:57:18","AP01SDTM":"2020-01-08 02:45:36","AP01EDTM":"2021-02-12 12:57:18","AP02SDTM":"2021-02-12 12:57:18","AP02EDTM":"2022-02-12 18:57:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":767,"DCSREAS":"DEATH","DTHDT":"2022-03-31","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-03-31","DTHADY":812,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2736,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.23766,"AVALU":"mg/L","BASE2":10.23766,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-03-11 02:45:36","ADY":63,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-15-id-36","SUBJID":"id-36","SITEID":"BRA-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-15","INVNAM":"Dr. BRA-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.40685,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 02:45:36","TRTEDTM":"2022-02-12 18:57:18","TRT01SDTM":"2020-01-08 02:45:36","TRT01EDTM":"2021-02-12 12:57:18","TRT02SDTM":"2021-02-12 12:57:18","TRT02EDTM":"2022-02-12 18:57:18","AP01SDTM":"2020-01-08 02:45:36","AP01EDTM":"2021-02-12 12:57:18","AP02SDTM":"2021-02-12 12:57:18","AP02EDTM":"2022-02-12 18:57:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":767,"DCSREAS":"DEATH","DTHDT":"2022-03-31","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-03-31","DTHADY":812,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6937,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.15387,"AVALU":"mg/L","BASE2":10.23766,"BASE":8.15387,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.08379,"PCHG2":-20.35415,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-14 02:45:36","ADY":97,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-15-id-36","SUBJID":"id-36","SITEID":"BRA-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-15","INVNAM":"Dr. BRA-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.40685,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 02:45:36","TRTEDTM":"2022-02-12 18:57:18","TRT01SDTM":"2020-01-08 02:45:36","TRT01EDTM":"2021-02-12 12:57:18","TRT02SDTM":"2021-02-12 12:57:18","TRT02EDTM":"2022-02-12 18:57:18","AP01SDTM":"2020-01-08 02:45:36","AP01EDTM":"2021-02-12 12:57:18","AP02SDTM":"2021-02-12 12:57:18","AP02EDTM":"2022-02-12 18:57:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":767,"DCSREAS":"DEATH","DTHDT":"2022-03-31","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-03-31","DTHADY":812,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":959,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.61279,"AVALU":"mg/L","BASE2":10.23766,"BASE":8.15387,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.62487,"PCHG2":-15.87145,"CHG":0.45892,"PCHG":5.62828,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-15 02:45:36","ADY":220,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-15-id-36","SUBJID":"id-36","SITEID":"BRA-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-15","INVNAM":"Dr. BRA-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.40685,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 02:45:36","TRTEDTM":"2022-02-12 18:57:18","TRT01SDTM":"2020-01-08 02:45:36","TRT01EDTM":"2021-02-12 12:57:18","TRT02SDTM":"2021-02-12 12:57:18","TRT02EDTM":"2022-02-12 18:57:18","AP01SDTM":"2020-01-08 02:45:36","AP01EDTM":"2021-02-12 12:57:18","AP02SDTM":"2021-02-12 12:57:18","AP02EDTM":"2022-02-12 18:57:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":767,"DCSREAS":"DEATH","DTHDT":"2022-03-31","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-03-31","DTHADY":812,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6172,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.82551,"AVALU":"mg/L","BASE2":10.23766,"BASE":8.15387,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.41215,"PCHG2":-13.79366,"CHG":0.67164,"PCHG":8.23707,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-25 02:45:36","ADY":442,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-15-id-36","SUBJID":"id-36","SITEID":"BRA-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-15","INVNAM":"Dr. BRA-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.40685,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 02:45:36","TRTEDTM":"2022-02-12 18:57:18","TRT01SDTM":"2020-01-08 02:45:36","TRT01EDTM":"2021-02-12 12:57:18","TRT02SDTM":"2021-02-12 12:57:18","TRT02EDTM":"2022-02-12 18:57:18","AP01SDTM":"2020-01-08 02:45:36","AP01EDTM":"2021-02-12 12:57:18","AP02SDTM":"2021-02-12 12:57:18","AP02EDTM":"2022-02-12 18:57:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":767,"DCSREAS":"DEATH","DTHDT":"2022-03-31","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-03-31","DTHADY":812,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5638,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.13767,"AVALU":"mg/L","BASE2":10.23766,"BASE":8.15387,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.09998,"PCHG2":-10.74449,"CHG":0.9838,"PCHG":12.06548,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-21 02:45:36","ADY":499,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-15-id-36","SUBJID":"id-36","SITEID":"BRA-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-15","INVNAM":"Dr. BRA-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.40685,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 02:45:36","TRTEDTM":"2022-02-12 18:57:18","TRT01SDTM":"2020-01-08 02:45:36","TRT01EDTM":"2021-02-12 12:57:18","TRT02SDTM":"2021-02-12 12:57:18","TRT02EDTM":"2022-02-12 18:57:18","AP01SDTM":"2020-01-08 02:45:36","AP01EDTM":"2021-02-12 12:57:18","AP02SDTM":"2021-02-12 12:57:18","AP02EDTM":"2022-02-12 18:57:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":767,"DCSREAS":"DEATH","DTHDT":"2022-03-31","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-03-31","DTHADY":812,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6781,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.58461,"AVALU":"mg/L","BASE2":10.23766,"BASE":8.15387,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.65304,"PCHG2":-25.91456,"CHG":-0.56926,"PCHG":-6.98143,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-05-26 02:45:36","ADY":504,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-15-id-36","SUBJID":"id-36","SITEID":"BRA-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-15","INVNAM":"Dr. BRA-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.40685,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 02:45:36","TRTEDTM":"2022-02-12 18:57:18","TRT01SDTM":"2020-01-08 02:45:36","TRT01EDTM":"2021-02-12 12:57:18","TRT02SDTM":"2021-02-12 12:57:18","TRT02EDTM":"2022-02-12 18:57:18","AP01SDTM":"2020-01-08 02:45:36","AP01EDTM":"2021-02-12 12:57:18","AP02SDTM":"2021-02-12 12:57:18","AP02EDTM":"2022-02-12 18:57:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":767,"DCSREAS":"DEATH","DTHDT":"2022-03-31","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-03-31","DTHADY":812,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6688,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.32342,"AVALU":"mg/L","BASE2":10.23766,"BASE":8.15387,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08576,"PCHG2":0.83768,"CHG":2.16955,"PCHG":26.60757,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2021-10-23 02:45:36","ADY":654,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-15-id-36","SUBJID":"id-36","SITEID":"BRA-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-15","INVNAM":"Dr. BRA-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.40685,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 02:45:36","TRTEDTM":"2022-02-12 18:57:18","TRT01SDTM":"2020-01-08 02:45:36","TRT01EDTM":"2021-02-12 12:57:18","TRT02SDTM":"2021-02-12 12:57:18","TRT02EDTM":"2022-02-12 18:57:18","AP01SDTM":"2020-01-08 02:45:36","AP01EDTM":"2021-02-12 12:57:18","AP02SDTM":"2021-02-12 12:57:18","AP02EDTM":"2022-02-12 18:57:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":767,"DCSREAS":"DEATH","DTHDT":"2022-03-31","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-03-31","DTHADY":812,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7251,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0181,"AVALU":"g/L","BASE2":3.0181,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-03-11 02:45:36","ADY":63,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-15-id-36","SUBJID":"id-36","SITEID":"BRA-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-15","INVNAM":"Dr. BRA-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.40685,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 02:45:36","TRTEDTM":"2022-02-12 18:57:18","TRT01SDTM":"2020-01-08 02:45:36","TRT01EDTM":"2021-02-12 12:57:18","TRT02SDTM":"2021-02-12 12:57:18","TRT02EDTM":"2022-02-12 18:57:18","AP01SDTM":"2020-01-08 02:45:36","AP01EDTM":"2021-02-12 12:57:18","AP02SDTM":"2021-02-12 12:57:18","AP02EDTM":"2022-02-12 18:57:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":767,"DCSREAS":"DEATH","DTHDT":"2022-03-31","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-03-31","DTHADY":812,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7901,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84072,"AVALU":"g/L","BASE2":3.0181,"BASE":2.84072,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.17738,"PCHG2":-5.87712,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-14 02:45:36","ADY":97,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-15-id-36","SUBJID":"id-36","SITEID":"BRA-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-15","INVNAM":"Dr. BRA-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.40685,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 02:45:36","TRTEDTM":"2022-02-12 18:57:18","TRT01SDTM":"2020-01-08 02:45:36","TRT01EDTM":"2021-02-12 12:57:18","TRT02SDTM":"2021-02-12 12:57:18","TRT02EDTM":"2022-02-12 18:57:18","AP01SDTM":"2020-01-08 02:45:36","AP01EDTM":"2021-02-12 12:57:18","AP02SDTM":"2021-02-12 12:57:18","AP02EDTM":"2022-02-12 18:57:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":767,"DCSREAS":"DEATH","DTHDT":"2022-03-31","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-03-31","DTHADY":812,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":504,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93659,"AVALU":"g/L","BASE2":3.0181,"BASE":2.84072,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08151,"PCHG2":-2.70083,"CHG":0.09586,"PCHG":3.37462,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-15 02:45:36","ADY":220,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-15-id-36","SUBJID":"id-36","SITEID":"BRA-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-15","INVNAM":"Dr. BRA-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.40685,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 02:45:36","TRTEDTM":"2022-02-12 18:57:18","TRT01SDTM":"2020-01-08 02:45:36","TRT01EDTM":"2021-02-12 12:57:18","TRT02SDTM":"2021-02-12 12:57:18","TRT02EDTM":"2022-02-12 18:57:18","AP01SDTM":"2020-01-08 02:45:36","AP01EDTM":"2021-02-12 12:57:18","AP02SDTM":"2021-02-12 12:57:18","AP02EDTM":"2022-02-12 18:57:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":767,"DCSREAS":"DEATH","DTHDT":"2022-03-31","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-03-31","DTHADY":812,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3110,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99014,"AVALU":"g/L","BASE2":3.0181,"BASE":2.84072,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02796,"PCHG2":-0.9263,"CHG":0.14942,"PCHG":5.25995,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-25 02:45:36","ADY":442,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-15-id-36","SUBJID":"id-36","SITEID":"BRA-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-15","INVNAM":"Dr. BRA-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.40685,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 02:45:36","TRTEDTM":"2022-02-12 18:57:18","TRT01SDTM":"2020-01-08 02:45:36","TRT01EDTM":"2021-02-12 12:57:18","TRT02SDTM":"2021-02-12 12:57:18","TRT02EDTM":"2022-02-12 18:57:18","AP01SDTM":"2020-01-08 02:45:36","AP01EDTM":"2021-02-12 12:57:18","AP02SDTM":"2021-02-12 12:57:18","AP02EDTM":"2022-02-12 18:57:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":767,"DCSREAS":"DEATH","DTHDT":"2022-03-31","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-03-31","DTHADY":812,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":690,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0312,"AVALU":"g/L","BASE2":3.0181,"BASE":2.84072,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0131,"PCHG2":0.43403,"CHG":0.19048,"PCHG":6.70522,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-05-21 02:45:36","ADY":499,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-15-id-36","SUBJID":"id-36","SITEID":"BRA-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-15","INVNAM":"Dr. BRA-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.40685,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 02:45:36","TRTEDTM":"2022-02-12 18:57:18","TRT01SDTM":"2020-01-08 02:45:36","TRT01EDTM":"2021-02-12 12:57:18","TRT02SDTM":"2021-02-12 12:57:18","TRT02EDTM":"2022-02-12 18:57:18","AP01SDTM":"2020-01-08 02:45:36","AP01EDTM":"2021-02-12 12:57:18","AP02SDTM":"2021-02-12 12:57:18","AP02EDTM":"2022-02-12 18:57:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":767,"DCSREAS":"DEATH","DTHDT":"2022-03-31","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-03-31","DTHADY":812,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2260,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0342,"AVALU":"g/L","BASE2":3.0181,"BASE":2.84072,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0161,"PCHG2":0.53353,"CHG":0.19348,"PCHG":6.81093,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-05-26 02:45:36","ADY":504,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-15-id-36","SUBJID":"id-36","SITEID":"BRA-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"Y","INVID":"INV ID BRA-15","INVNAM":"Dr. BRA-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.40685,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 02:45:36","TRTEDTM":"2022-02-12 18:57:18","TRT01SDTM":"2020-01-08 02:45:36","TRT01EDTM":"2021-02-12 12:57:18","TRT02SDTM":"2021-02-12 12:57:18","TRT02EDTM":"2022-02-12 18:57:18","AP01SDTM":"2020-01-08 02:45:36","AP01EDTM":"2021-02-12 12:57:18","AP02SDTM":"2021-02-12 12:57:18","AP02EDTM":"2022-02-12 18:57:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":767,"DCSREAS":"DEATH","DTHDT":"2022-03-31","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-03-31","DTHADY":812,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7366,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99061,"AVALU":"g/L","BASE2":3.0181,"BASE":2.84072,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02749,"PCHG2":-0.91078,"CHG":0.14989,"PCHG":5.27644,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-23 02:45:36","ADY":654,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-101","SUBJID":"id-101","SITEID":"BRA-2","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.18055,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-26 00:24:28","TRTEDTM":"2023-06-26 18:24:28","TRT01SDTM":"2020-06-26 00:24:28","TRT01EDTM":"2022-06-26 12:24:28","TRT02SDTM":"2022-06-26 12:24:28","TRT02EDTM":"2023-06-26 18:24:28","AP01SDTM":"2020-06-26 00:24:28","AP01EDTM":"2022-06-26 12:24:28","AP02SDTM":"2022-06-26 12:24:28","AP02EDTM":"2023-06-26 18:24:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-26","EOSDY":1096,"LSTALVDT":"2023-07-22","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7689,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.41067,"AVALU":"U/L","BASE2":15.41067,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-4","ADTM":"2020-07-03 00:24:28","ADY":7,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-101","SUBJID":"id-101","SITEID":"BRA-2","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.18055,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-26 00:24:28","TRTEDTM":"2023-06-26 18:24:28","TRT01SDTM":"2020-06-26 00:24:28","TRT01EDTM":"2022-06-26 12:24:28","TRT02SDTM":"2022-06-26 12:24:28","TRT02EDTM":"2023-06-26 18:24:28","AP01SDTM":"2020-06-26 00:24:28","AP01EDTM":"2022-06-26 12:24:28","AP02SDTM":"2022-06-26 12:24:28","AP02EDTM":"2023-06-26 18:24:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-26","EOSDY":1096,"LSTALVDT":"2023-07-22","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1883,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.65782,"AVALU":"U/L","BASE2":15.41067,"BASE":2.65782,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-12.75285,"PCHG2":-82.75335,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-4","BTOXGR":"-4","ADTM":"2021-01-21 00:24:28","ADY":209,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-101","SUBJID":"id-101","SITEID":"BRA-2","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.18055,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-26 00:24:28","TRTEDTM":"2023-06-26 18:24:28","TRT01SDTM":"2020-06-26 00:24:28","TRT01EDTM":"2022-06-26 12:24:28","TRT02SDTM":"2022-06-26 12:24:28","TRT02EDTM":"2023-06-26 18:24:28","AP01SDTM":"2020-06-26 00:24:28","AP01EDTM":"2022-06-26 12:24:28","AP02SDTM":"2022-06-26 12:24:28","AP02EDTM":"2023-06-26 18:24:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-26","EOSDY":1096,"LSTALVDT":"2023-07-22","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2234,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.78736,"AVALU":"U/L","BASE2":15.41067,"BASE":2.65782,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.62331,"PCHG2":-17.02269,"CHG":10.12954,"PCHG":381.12138,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-07-27 00:24:28","ADY":396,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-101","SUBJID":"id-101","SITEID":"BRA-2","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.18055,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-26 00:24:28","TRTEDTM":"2023-06-26 18:24:28","TRT01SDTM":"2020-06-26 00:24:28","TRT01EDTM":"2022-06-26 12:24:28","TRT02SDTM":"2022-06-26 12:24:28","TRT02EDTM":"2023-06-26 18:24:28","AP01SDTM":"2020-06-26 00:24:28","AP01EDTM":"2022-06-26 12:24:28","AP02SDTM":"2022-06-26 12:24:28","AP02EDTM":"2023-06-26 18:24:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-26","EOSDY":1096,"LSTALVDT":"2023-07-22","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":921,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.49485,"AVALU":"U/L","BASE2":15.41067,"BASE":2.65782,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.08417,"PCHG2":78.41431,"CHG":24.83702,"PCHG":934.48695,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-12-25 00:24:28","ADY":547,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-101","SUBJID":"id-101","SITEID":"BRA-2","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.18055,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-26 00:24:28","TRTEDTM":"2023-06-26 18:24:28","TRT01SDTM":"2020-06-26 00:24:28","TRT01EDTM":"2022-06-26 12:24:28","TRT02SDTM":"2022-06-26 12:24:28","TRT02EDTM":"2023-06-26 18:24:28","AP01SDTM":"2020-06-26 00:24:28","AP01EDTM":"2022-06-26 12:24:28","AP02SDTM":"2022-06-26 12:24:28","AP02EDTM":"2023-06-26 18:24:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-26","EOSDY":1096,"LSTALVDT":"2023-07-22","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3264,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.22383,"AVALU":"U/L","BASE2":15.41067,"BASE":2.65782,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.81316,"PCHG2":57.18867,"CHG":21.56601,"PCHG":811.41581,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2022-06-21 00:24:28","ADY":725,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-101","SUBJID":"id-101","SITEID":"BRA-2","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.18055,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-26 00:24:28","TRTEDTM":"2023-06-26 18:24:28","TRT01SDTM":"2020-06-26 00:24:28","TRT01EDTM":"2022-06-26 12:24:28","TRT02SDTM":"2022-06-26 12:24:28","TRT02EDTM":"2023-06-26 18:24:28","AP01SDTM":"2020-06-26 00:24:28","AP01EDTM":"2022-06-26 12:24:28","AP02SDTM":"2022-06-26 12:24:28","AP02EDTM":"2023-06-26 18:24:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-26","EOSDY":1096,"LSTALVDT":"2023-07-22","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":119,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.28624,"AVALU":"U/L","BASE2":15.41067,"BASE":2.65782,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.12443,"PCHG2":-46.2305,"CHG":5.62842,"PCHG":211.76782,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2023-01-17 00:24:28","ADY":935,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-101","SUBJID":"id-101","SITEID":"BRA-2","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.18055,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-26 00:24:28","TRTEDTM":"2023-06-26 18:24:28","TRT01SDTM":"2020-06-26 00:24:28","TRT01EDTM":"2022-06-26 12:24:28","TRT02SDTM":"2022-06-26 12:24:28","TRT02EDTM":"2023-06-26 18:24:28","AP01SDTM":"2020-06-26 00:24:28","AP01EDTM":"2022-06-26 12:24:28","AP02SDTM":"2022-06-26 12:24:28","AP02EDTM":"2023-06-26 18:24:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-26","EOSDY":1096,"LSTALVDT":"2023-07-22","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3547,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.81176,"AVALU":"U/L","BASE2":15.41067,"BASE":2.65782,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.40108,"PCHG2":54.5147,"CHG":21.15393,"PCHG":795.91152,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2023-06-24 00:24:28","ADY":1093,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-101","SUBJID":"id-101","SITEID":"BRA-2","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.18055,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-26 00:24:28","TRTEDTM":"2023-06-26 18:24:28","TRT01SDTM":"2020-06-26 00:24:28","TRT01EDTM":"2022-06-26 12:24:28","TRT02SDTM":"2022-06-26 12:24:28","TRT02EDTM":"2023-06-26 18:24:28","AP01SDTM":"2020-06-26 00:24:28","AP01EDTM":"2022-06-26 12:24:28","AP02SDTM":"2022-06-26 12:24:28","AP02EDTM":"2023-06-26 18:24:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-26","EOSDY":1096,"LSTALVDT":"2023-07-22","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5076,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.07477,"AVALU":"mg/L","BASE2":9.07477,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-07-03 00:24:28","ADY":7,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-101","SUBJID":"id-101","SITEID":"BRA-2","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.18055,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-26 00:24:28","TRTEDTM":"2023-06-26 18:24:28","TRT01SDTM":"2020-06-26 00:24:28","TRT01EDTM":"2022-06-26 12:24:28","TRT02SDTM":"2022-06-26 12:24:28","TRT02EDTM":"2023-06-26 18:24:28","AP01SDTM":"2020-06-26 00:24:28","AP01EDTM":"2022-06-26 12:24:28","AP02SDTM":"2022-06-26 12:24:28","AP02EDTM":"2023-06-26 18:24:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-26","EOSDY":1096,"LSTALVDT":"2023-07-22","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5846,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.47942,"AVALU":"mg/L","BASE2":9.07477,"BASE":10.47942,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.40465,"PCHG2":15.47868,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2021-01-21 00:24:28","ADY":209,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-101","SUBJID":"id-101","SITEID":"BRA-2","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.18055,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-26 00:24:28","TRTEDTM":"2023-06-26 18:24:28","TRT01SDTM":"2020-06-26 00:24:28","TRT01EDTM":"2022-06-26 12:24:28","TRT02SDTM":"2022-06-26 12:24:28","TRT02EDTM":"2023-06-26 18:24:28","AP01SDTM":"2020-06-26 00:24:28","AP01EDTM":"2022-06-26 12:24:28","AP02SDTM":"2022-06-26 12:24:28","AP02EDTM":"2023-06-26 18:24:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-26","EOSDY":1096,"LSTALVDT":"2023-07-22","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7129,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.50173,"AVALU":"mg/L","BASE2":9.07477,"BASE":10.47942,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.42697,"PCHG2":15.72455,"CHG":0.02231,"PCHG":0.21291,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"4","BTOXGR":"3","ADTM":"2021-07-27 00:24:28","ADY":396,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-101","SUBJID":"id-101","SITEID":"BRA-2","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.18055,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-26 00:24:28","TRTEDTM":"2023-06-26 18:24:28","TRT01SDTM":"2020-06-26 00:24:28","TRT01EDTM":"2022-06-26 12:24:28","TRT02SDTM":"2022-06-26 12:24:28","TRT02EDTM":"2023-06-26 18:24:28","AP01SDTM":"2020-06-26 00:24:28","AP01EDTM":"2022-06-26 12:24:28","AP02SDTM":"2022-06-26 12:24:28","AP02EDTM":"2023-06-26 18:24:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-26","EOSDY":1096,"LSTALVDT":"2023-07-22","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2560,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.71679,"AVALU":"mg/L","BASE2":9.07477,"BASE":10.47942,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.35798,"PCHG2":-14.96431,"CHG":-2.76263,"PCHG":-26.36243,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-2","BTOXGR":"3","ADTM":"2021-12-25 00:24:28","ADY":547,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-101","SUBJID":"id-101","SITEID":"BRA-2","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.18055,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-26 00:24:28","TRTEDTM":"2023-06-26 18:24:28","TRT01SDTM":"2020-06-26 00:24:28","TRT01EDTM":"2022-06-26 12:24:28","TRT02SDTM":"2022-06-26 12:24:28","TRT02EDTM":"2023-06-26 18:24:28","AP01SDTM":"2020-06-26 00:24:28","AP01EDTM":"2022-06-26 12:24:28","AP02SDTM":"2022-06-26 12:24:28","AP02EDTM":"2023-06-26 18:24:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-26","EOSDY":1096,"LSTALVDT":"2023-07-22","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6393,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.72153,"AVALU":"mg/L","BASE2":9.07477,"BASE":10.47942,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.64676,"PCHG2":7.12703,"CHG":-0.75789,"PCHG":-7.2322,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-06-21 00:24:28","ADY":725,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-101","SUBJID":"id-101","SITEID":"BRA-2","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.18055,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-26 00:24:28","TRTEDTM":"2023-06-26 18:24:28","TRT01SDTM":"2020-06-26 00:24:28","TRT01EDTM":"2022-06-26 12:24:28","TRT02SDTM":"2022-06-26 12:24:28","TRT02EDTM":"2023-06-26 18:24:28","AP01SDTM":"2020-06-26 00:24:28","AP01EDTM":"2022-06-26 12:24:28","AP02SDTM":"2022-06-26 12:24:28","AP02EDTM":"2023-06-26 18:24:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-26","EOSDY":1096,"LSTALVDT":"2023-07-22","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6815,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.10459,"AVALU":"mg/L","BASE2":9.07477,"BASE":10.47942,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02983,"PCHG2":0.32866,"CHG":-1.37483,"PCHG":-13.11932,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2023-01-17 00:24:28","ADY":935,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-101","SUBJID":"id-101","SITEID":"BRA-2","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.18055,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-26 00:24:28","TRTEDTM":"2023-06-26 18:24:28","TRT01SDTM":"2020-06-26 00:24:28","TRT01EDTM":"2022-06-26 12:24:28","TRT02SDTM":"2022-06-26 12:24:28","TRT02EDTM":"2023-06-26 18:24:28","AP01SDTM":"2020-06-26 00:24:28","AP01EDTM":"2022-06-26 12:24:28","AP02SDTM":"2022-06-26 12:24:28","AP02EDTM":"2023-06-26 18:24:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-26","EOSDY":1096,"LSTALVDT":"2023-07-22","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3800,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.3796,"AVALU":"mg/L","BASE2":9.07477,"BASE":10.47942,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.30484,"PCHG2":14.37875,"CHG":-0.09982,"PCHG":-0.95249,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"4","BTOXGR":"3","ADTM":"2023-06-24 00:24:28","ADY":1093,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-101","SUBJID":"id-101","SITEID":"BRA-2","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.18055,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-26 00:24:28","TRTEDTM":"2023-06-26 18:24:28","TRT01SDTM":"2020-06-26 00:24:28","TRT01EDTM":"2022-06-26 12:24:28","TRT02SDTM":"2022-06-26 12:24:28","TRT02EDTM":"2023-06-26 18:24:28","AP01SDTM":"2020-06-26 00:24:28","AP01EDTM":"2022-06-26 12:24:28","AP02SDTM":"2022-06-26 12:24:28","AP02EDTM":"2023-06-26 18:24:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-26","EOSDY":1096,"LSTALVDT":"2023-07-22","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7902,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96191,"AVALU":"g/L","BASE2":2.96191,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-03 00:24:28","ADY":7,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-101","SUBJID":"id-101","SITEID":"BRA-2","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.18055,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-26 00:24:28","TRTEDTM":"2023-06-26 18:24:28","TRT01SDTM":"2020-06-26 00:24:28","TRT01EDTM":"2022-06-26 12:24:28","TRT02SDTM":"2022-06-26 12:24:28","TRT02EDTM":"2023-06-26 18:24:28","AP01SDTM":"2020-06-26 00:24:28","AP01EDTM":"2022-06-26 12:24:28","AP02SDTM":"2022-06-26 12:24:28","AP02EDTM":"2023-06-26 18:24:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-26","EOSDY":1096,"LSTALVDT":"2023-07-22","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4553,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85789,"AVALU":"g/L","BASE2":2.96191,"BASE":2.85789,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.10402,"PCHG2":-3.51189,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-21 00:24:28","ADY":209,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-101","SUBJID":"id-101","SITEID":"BRA-2","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.18055,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-26 00:24:28","TRTEDTM":"2023-06-26 18:24:28","TRT01SDTM":"2020-06-26 00:24:28","TRT01EDTM":"2022-06-26 12:24:28","TRT02SDTM":"2022-06-26 12:24:28","TRT02EDTM":"2023-06-26 18:24:28","AP01SDTM":"2020-06-26 00:24:28","AP01EDTM":"2022-06-26 12:24:28","AP02SDTM":"2022-06-26 12:24:28","AP02EDTM":"2023-06-26 18:24:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-26","EOSDY":1096,"LSTALVDT":"2023-07-22","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6094,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82437,"AVALU":"g/L","BASE2":2.96191,"BASE":2.85789,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13753,"PCHG2":-4.64339,"CHG":-0.03351,"PCHG":-1.17268,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-27 00:24:28","ADY":396,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-101","SUBJID":"id-101","SITEID":"BRA-2","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.18055,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-26 00:24:28","TRTEDTM":"2023-06-26 18:24:28","TRT01SDTM":"2020-06-26 00:24:28","TRT01EDTM":"2022-06-26 12:24:28","TRT02SDTM":"2022-06-26 12:24:28","TRT02EDTM":"2023-06-26 18:24:28","AP01SDTM":"2020-06-26 00:24:28","AP01EDTM":"2022-06-26 12:24:28","AP02SDTM":"2022-06-26 12:24:28","AP02EDTM":"2023-06-26 18:24:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-26","EOSDY":1096,"LSTALVDT":"2023-07-22","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1562,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75777,"AVALU":"g/L","BASE2":2.96191,"BASE":2.85789,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20413,"PCHG2":-6.89201,"CHG":-0.10012,"PCHG":-3.50315,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-25 00:24:28","ADY":547,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-101","SUBJID":"id-101","SITEID":"BRA-2","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.18055,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-26 00:24:28","TRTEDTM":"2023-06-26 18:24:28","TRT01SDTM":"2020-06-26 00:24:28","TRT01EDTM":"2022-06-26 12:24:28","TRT02SDTM":"2022-06-26 12:24:28","TRT02EDTM":"2023-06-26 18:24:28","AP01SDTM":"2020-06-26 00:24:28","AP01EDTM":"2022-06-26 12:24:28","AP02SDTM":"2022-06-26 12:24:28","AP02EDTM":"2023-06-26 18:24:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-26","EOSDY":1096,"LSTALVDT":"2023-07-22","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1641,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7577,"AVALU":"g/L","BASE2":2.96191,"BASE":2.85789,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.2042,"PCHG2":-6.8943,"CHG":-0.10018,"PCHG":-3.50552,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-21 00:24:28","ADY":725,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-101","SUBJID":"id-101","SITEID":"BRA-2","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.18055,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-26 00:24:28","TRTEDTM":"2023-06-26 18:24:28","TRT01SDTM":"2020-06-26 00:24:28","TRT01EDTM":"2022-06-26 12:24:28","TRT02SDTM":"2022-06-26 12:24:28","TRT02EDTM":"2023-06-26 18:24:28","AP01SDTM":"2020-06-26 00:24:28","AP01EDTM":"2022-06-26 12:24:28","AP02SDTM":"2022-06-26 12:24:28","AP02EDTM":"2023-06-26 18:24:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-26","EOSDY":1096,"LSTALVDT":"2023-07-22","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":628,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05496,"AVALU":"g/L","BASE2":2.96191,"BASE":2.85789,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09305,"PCHG2":3.14156,"CHG":0.19707,"PCHG":6.89562,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2023-01-17 00:24:28","ADY":935,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-101","SUBJID":"id-101","SITEID":"BRA-2","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.18055,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-26 00:24:28","TRTEDTM":"2023-06-26 18:24:28","TRT01SDTM":"2020-06-26 00:24:28","TRT01EDTM":"2022-06-26 12:24:28","TRT02SDTM":"2022-06-26 12:24:28","TRT02EDTM":"2023-06-26 18:24:28","AP01SDTM":"2020-06-26 00:24:28","AP01EDTM":"2022-06-26 12:24:28","AP02SDTM":"2022-06-26 12:24:28","AP02EDTM":"2023-06-26 18:24:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-26","EOSDY":1096,"LSTALVDT":"2023-07-22","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3124,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90117,"AVALU":"g/L","BASE2":2.96191,"BASE":2.85789,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06073,"PCHG2":-2.05046,"CHG":0.04329,"PCHG":1.51462,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-24 00:24:28","ADY":1093,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-296","SUBJID":"id-296","SITEID":"BRA-2","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.75083,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-19","TRTSDTM":"2021-01-22 02:18:40","TRTEDTM":"2024-01-22 20:18:40","TRT01SDTM":"2021-01-22 02:18:40","TRT01EDTM":"2023-01-22 14:18:40","TRT02SDTM":"2023-01-22 14:18:40","TRT02EDTM":"2024-01-22 20:18:40","AP01SDTM":"2021-01-22 02:18:40","AP01EDTM":"2023-01-22 14:18:40","AP02SDTM":"2023-01-22 14:18:40","AP02EDTM":"2024-01-22 20:18:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-22","EOSDY":1096,"LSTALVDT":"2024-02-20","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":378,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.8883,"AVALU":"U/L","BASE2":9.8883,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-02 02:18:40","ADY":223,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-296","SUBJID":"id-296","SITEID":"BRA-2","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.75083,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-19","TRTSDTM":"2021-01-22 02:18:40","TRTEDTM":"2024-01-22 20:18:40","TRT01SDTM":"2021-01-22 02:18:40","TRT01EDTM":"2023-01-22 14:18:40","TRT02SDTM":"2023-01-22 14:18:40","TRT02EDTM":"2024-01-22 20:18:40","AP01SDTM":"2021-01-22 02:18:40","AP01EDTM":"2023-01-22 14:18:40","AP02SDTM":"2023-01-22 14:18:40","AP02EDTM":"2024-01-22 20:18:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-22","EOSDY":1096,"LSTALVDT":"2024-02-20","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4280,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.64719,"AVALU":"U/L","BASE2":9.8883,"BASE":17.64719,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":7.75889,"PCHG2":78.46538,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-26 02:18:40","ADY":247,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-296","SUBJID":"id-296","SITEID":"BRA-2","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.75083,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-19","TRTSDTM":"2021-01-22 02:18:40","TRTEDTM":"2024-01-22 20:18:40","TRT01SDTM":"2021-01-22 02:18:40","TRT01EDTM":"2023-01-22 14:18:40","TRT02SDTM":"2023-01-22 14:18:40","TRT02EDTM":"2024-01-22 20:18:40","AP01SDTM":"2021-01-22 02:18:40","AP01EDTM":"2023-01-22 14:18:40","AP02SDTM":"2023-01-22 14:18:40","AP02EDTM":"2024-01-22 20:18:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-22","EOSDY":1096,"LSTALVDT":"2024-02-20","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7975,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.58904,"AVALU":"U/L","BASE2":9.8883,"BASE":17.64719,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.29926,"PCHG2":-73.81711,"CHG":-15.05815,"PCHG":-85.32887,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-10-30 02:18:40","ADY":281,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-296","SUBJID":"id-296","SITEID":"BRA-2","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.75083,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-19","TRTSDTM":"2021-01-22 02:18:40","TRTEDTM":"2024-01-22 20:18:40","TRT01SDTM":"2021-01-22 02:18:40","TRT01EDTM":"2023-01-22 14:18:40","TRT02SDTM":"2023-01-22 14:18:40","TRT02EDTM":"2024-01-22 20:18:40","AP01SDTM":"2021-01-22 02:18:40","AP01EDTM":"2023-01-22 14:18:40","AP02SDTM":"2023-01-22 14:18:40","AP02EDTM":"2024-01-22 20:18:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-22","EOSDY":1096,"LSTALVDT":"2024-02-20","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2831,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.97456,"AVALU":"U/L","BASE2":9.8883,"BASE":17.64719,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.08626,"PCHG2":71.6631,"CHG":-0.67263,"PCHG":-3.81154,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-16 02:18:40","ADY":418,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-296","SUBJID":"id-296","SITEID":"BRA-2","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.75083,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-19","TRTSDTM":"2021-01-22 02:18:40","TRTEDTM":"2024-01-22 20:18:40","TRT01SDTM":"2021-01-22 02:18:40","TRT01EDTM":"2023-01-22 14:18:40","TRT02SDTM":"2023-01-22 14:18:40","TRT02EDTM":"2024-01-22 20:18:40","AP01SDTM":"2021-01-22 02:18:40","AP01EDTM":"2023-01-22 14:18:40","AP02SDTM":"2023-01-22 14:18:40","AP02EDTM":"2024-01-22 20:18:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-22","EOSDY":1096,"LSTALVDT":"2024-02-20","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5105,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.87745,"AVALU":"U/L","BASE2":9.8883,"BASE":17.64719,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.01085,"PCHG2":-60.78749,"CHG":-13.76974,"PCHG":-78.02795,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2023-01-26 02:18:40","ADY":734,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-296","SUBJID":"id-296","SITEID":"BRA-2","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.75083,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-19","TRTSDTM":"2021-01-22 02:18:40","TRTEDTM":"2024-01-22 20:18:40","TRT01SDTM":"2021-01-22 02:18:40","TRT01EDTM":"2023-01-22 14:18:40","TRT02SDTM":"2023-01-22 14:18:40","TRT02EDTM":"2024-01-22 20:18:40","AP01SDTM":"2021-01-22 02:18:40","AP01EDTM":"2023-01-22 14:18:40","AP02SDTM":"2023-01-22 14:18:40","AP02EDTM":"2024-01-22 20:18:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-22","EOSDY":1096,"LSTALVDT":"2024-02-20","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2540,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.14809,"AVALU":"U/L","BASE2":9.8883,"BASE":17.64719,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.25979,"PCHG2":32.96616,"CHG":-4.4991,"PCHG":-25.49471,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-01 02:18:40","ADY":799,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-296","SUBJID":"id-296","SITEID":"BRA-2","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.75083,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-19","TRTSDTM":"2021-01-22 02:18:40","TRTEDTM":"2024-01-22 20:18:40","TRT01SDTM":"2021-01-22 02:18:40","TRT01EDTM":"2023-01-22 14:18:40","TRT02SDTM":"2023-01-22 14:18:40","TRT02EDTM":"2024-01-22 20:18:40","AP01SDTM":"2021-01-22 02:18:40","AP01EDTM":"2023-01-22 14:18:40","AP02SDTM":"2023-01-22 14:18:40","AP02EDTM":"2024-01-22 20:18:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-22","EOSDY":1096,"LSTALVDT":"2024-02-20","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5478,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":40.01808,"AVALU":"U/L","BASE2":9.8883,"BASE":17.64719,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":30.12978,"PCHG2":304.70138,"CHG":22.37089,"PCHG":126.76744,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-25 02:18:40","ADY":914,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-296","SUBJID":"id-296","SITEID":"BRA-2","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.75083,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-19","TRTSDTM":"2021-01-22 02:18:40","TRTEDTM":"2024-01-22 20:18:40","TRT01SDTM":"2021-01-22 02:18:40","TRT01EDTM":"2023-01-22 14:18:40","TRT02SDTM":"2023-01-22 14:18:40","TRT02EDTM":"2024-01-22 20:18:40","AP01SDTM":"2021-01-22 02:18:40","AP01EDTM":"2023-01-22 14:18:40","AP02SDTM":"2023-01-22 14:18:40","AP02EDTM":"2024-01-22 20:18:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-22","EOSDY":1096,"LSTALVDT":"2024-02-20","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1217,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.95748,"AVALU":"mg/L","BASE2":9.95748,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-02 02:18:40","ADY":223,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-296","SUBJID":"id-296","SITEID":"BRA-2","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.75083,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-19","TRTSDTM":"2021-01-22 02:18:40","TRTEDTM":"2024-01-22 20:18:40","TRT01SDTM":"2021-01-22 02:18:40","TRT01EDTM":"2023-01-22 14:18:40","TRT02SDTM":"2023-01-22 14:18:40","TRT02EDTM":"2024-01-22 20:18:40","AP01SDTM":"2021-01-22 02:18:40","AP01EDTM":"2023-01-22 14:18:40","AP02SDTM":"2023-01-22 14:18:40","AP02EDTM":"2024-01-22 20:18:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-22","EOSDY":1096,"LSTALVDT":"2024-02-20","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2130,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.06716,"AVALU":"mg/L","BASE2":9.95748,"BASE":9.06716,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.89032,"PCHG2":-8.94121,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-26 02:18:40","ADY":247,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-296","SUBJID":"id-296","SITEID":"BRA-2","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.75083,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-19","TRTSDTM":"2021-01-22 02:18:40","TRTEDTM":"2024-01-22 20:18:40","TRT01SDTM":"2021-01-22 02:18:40","TRT01EDTM":"2023-01-22 14:18:40","TRT02SDTM":"2023-01-22 14:18:40","TRT02EDTM":"2024-01-22 20:18:40","AP01SDTM":"2021-01-22 02:18:40","AP01EDTM":"2023-01-22 14:18:40","AP02SDTM":"2023-01-22 14:18:40","AP02EDTM":"2024-01-22 20:18:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-22","EOSDY":1096,"LSTALVDT":"2024-02-20","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5577,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.01554,"AVALU":"mg/L","BASE2":9.95748,"BASE":9.06716,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.94194,"PCHG2":-19.50232,"CHG":-1.05162,"PCHG":-11.59813,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-30 02:18:40","ADY":281,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-296","SUBJID":"id-296","SITEID":"BRA-2","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.75083,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-19","TRTSDTM":"2021-01-22 02:18:40","TRTEDTM":"2024-01-22 20:18:40","TRT01SDTM":"2021-01-22 02:18:40","TRT01EDTM":"2023-01-22 14:18:40","TRT02SDTM":"2023-01-22 14:18:40","TRT02EDTM":"2024-01-22 20:18:40","AP01SDTM":"2021-01-22 02:18:40","AP01EDTM":"2023-01-22 14:18:40","AP02SDTM":"2023-01-22 14:18:40","AP02EDTM":"2024-01-22 20:18:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-22","EOSDY":1096,"LSTALVDT":"2024-02-20","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4150,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.85579,"AVALU":"mg/L","BASE2":9.95748,"BASE":9.06716,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10169,"PCHG2":-1.02126,"CHG":0.78863,"PCHG":8.69762,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-16 02:18:40","ADY":418,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-296","SUBJID":"id-296","SITEID":"BRA-2","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.75083,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-19","TRTSDTM":"2021-01-22 02:18:40","TRTEDTM":"2024-01-22 20:18:40","TRT01SDTM":"2021-01-22 02:18:40","TRT01EDTM":"2023-01-22 14:18:40","TRT02SDTM":"2023-01-22 14:18:40","TRT02EDTM":"2024-01-22 20:18:40","AP01SDTM":"2021-01-22 02:18:40","AP01EDTM":"2023-01-22 14:18:40","AP02SDTM":"2023-01-22 14:18:40","AP02EDTM":"2024-01-22 20:18:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-22","EOSDY":1096,"LSTALVDT":"2024-02-20","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2622,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.24194,"AVALU":"mg/L","BASE2":9.95748,"BASE":9.06716,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.71554,"PCHG2":-7.18594,"CHG":0.17478,"PCHG":1.92762,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-26 02:18:40","ADY":734,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-296","SUBJID":"id-296","SITEID":"BRA-2","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.75083,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-19","TRTSDTM":"2021-01-22 02:18:40","TRTEDTM":"2024-01-22 20:18:40","TRT01SDTM":"2021-01-22 02:18:40","TRT01EDTM":"2023-01-22 14:18:40","TRT02SDTM":"2023-01-22 14:18:40","TRT02EDTM":"2024-01-22 20:18:40","AP01SDTM":"2021-01-22 02:18:40","AP01EDTM":"2023-01-22 14:18:40","AP02SDTM":"2023-01-22 14:18:40","AP02EDTM":"2024-01-22 20:18:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-22","EOSDY":1096,"LSTALVDT":"2024-02-20","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1166,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.98187,"AVALU":"mg/L","BASE2":9.95748,"BASE":9.06716,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.9756,"PCHG2":-9.7977,"CHG":-0.08529,"PCHG":-0.9406,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-01 02:18:40","ADY":799,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-296","SUBJID":"id-296","SITEID":"BRA-2","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.75083,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-19","TRTSDTM":"2021-01-22 02:18:40","TRTEDTM":"2024-01-22 20:18:40","TRT01SDTM":"2021-01-22 02:18:40","TRT01EDTM":"2023-01-22 14:18:40","TRT02SDTM":"2023-01-22 14:18:40","TRT02EDTM":"2024-01-22 20:18:40","AP01SDTM":"2021-01-22 02:18:40","AP01EDTM":"2023-01-22 14:18:40","AP02SDTM":"2023-01-22 14:18:40","AP02EDTM":"2024-01-22 20:18:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-22","EOSDY":1096,"LSTALVDT":"2024-02-20","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6850,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.55849,"AVALU":"mg/L","BASE2":9.95748,"BASE":9.06716,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.39899,"PCHG2":-14.04965,"CHG":-0.50867,"PCHG":-5.61005,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-25 02:18:40","ADY":914,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-296","SUBJID":"id-296","SITEID":"BRA-2","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.75083,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-19","TRTSDTM":"2021-01-22 02:18:40","TRTEDTM":"2024-01-22 20:18:40","TRT01SDTM":"2021-01-22 02:18:40","TRT01EDTM":"2023-01-22 14:18:40","TRT02SDTM":"2023-01-22 14:18:40","TRT02EDTM":"2024-01-22 20:18:40","AP01SDTM":"2021-01-22 02:18:40","AP01EDTM":"2023-01-22 14:18:40","AP02SDTM":"2023-01-22 14:18:40","AP02EDTM":"2024-01-22 20:18:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-22","EOSDY":1096,"LSTALVDT":"2024-02-20","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1117,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96239,"AVALU":"g/L","BASE2":2.96239,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-02 02:18:40","ADY":223,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-296","SUBJID":"id-296","SITEID":"BRA-2","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.75083,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-19","TRTSDTM":"2021-01-22 02:18:40","TRTEDTM":"2024-01-22 20:18:40","TRT01SDTM":"2021-01-22 02:18:40","TRT01EDTM":"2023-01-22 14:18:40","TRT02SDTM":"2023-01-22 14:18:40","TRT02EDTM":"2024-01-22 20:18:40","AP01SDTM":"2021-01-22 02:18:40","AP01EDTM":"2023-01-22 14:18:40","AP02SDTM":"2023-01-22 14:18:40","AP02EDTM":"2024-01-22 20:18:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-22","EOSDY":1096,"LSTALVDT":"2024-02-20","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6334,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88135,"AVALU":"g/L","BASE2":2.96239,"BASE":2.88135,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.08104,"PCHG2":-2.73564,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-26 02:18:40","ADY":247,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-296","SUBJID":"id-296","SITEID":"BRA-2","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.75083,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-19","TRTSDTM":"2021-01-22 02:18:40","TRTEDTM":"2024-01-22 20:18:40","TRT01SDTM":"2021-01-22 02:18:40","TRT01EDTM":"2023-01-22 14:18:40","TRT02SDTM":"2023-01-22 14:18:40","TRT02EDTM":"2024-01-22 20:18:40","AP01SDTM":"2021-01-22 02:18:40","AP01EDTM":"2023-01-22 14:18:40","AP02SDTM":"2023-01-22 14:18:40","AP02EDTM":"2024-01-22 20:18:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-22","EOSDY":1096,"LSTALVDT":"2024-02-20","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5582,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89466,"AVALU":"g/L","BASE2":2.96239,"BASE":2.88135,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06773,"PCHG2":-2.28634,"CHG":0.01331,"PCHG":0.46193,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-30 02:18:40","ADY":281,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-296","SUBJID":"id-296","SITEID":"BRA-2","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.75083,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-19","TRTSDTM":"2021-01-22 02:18:40","TRTEDTM":"2024-01-22 20:18:40","TRT01SDTM":"2021-01-22 02:18:40","TRT01EDTM":"2023-01-22 14:18:40","TRT02SDTM":"2023-01-22 14:18:40","TRT02EDTM":"2024-01-22 20:18:40","AP01SDTM":"2021-01-22 02:18:40","AP01EDTM":"2023-01-22 14:18:40","AP02SDTM":"2023-01-22 14:18:40","AP02EDTM":"2024-01-22 20:18:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-22","EOSDY":1096,"LSTALVDT":"2024-02-20","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7892,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90679,"AVALU":"g/L","BASE2":2.96239,"BASE":2.88135,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0556,"PCHG2":-1.87673,"CHG":0.02544,"PCHG":0.88307,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-16 02:18:40","ADY":418,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-296","SUBJID":"id-296","SITEID":"BRA-2","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.75083,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-19","TRTSDTM":"2021-01-22 02:18:40","TRTEDTM":"2024-01-22 20:18:40","TRT01SDTM":"2021-01-22 02:18:40","TRT01EDTM":"2023-01-22 14:18:40","TRT02SDTM":"2023-01-22 14:18:40","TRT02EDTM":"2024-01-22 20:18:40","AP01SDTM":"2021-01-22 02:18:40","AP01EDTM":"2023-01-22 14:18:40","AP02SDTM":"2023-01-22 14:18:40","AP02EDTM":"2024-01-22 20:18:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-22","EOSDY":1096,"LSTALVDT":"2024-02-20","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4913,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86549,"AVALU":"g/L","BASE2":2.96239,"BASE":2.88135,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0969,"PCHG2":-3.27101,"CHG":-0.01586,"PCHG":-0.55043,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-26 02:18:40","ADY":734,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-296","SUBJID":"id-296","SITEID":"BRA-2","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.75083,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-19","TRTSDTM":"2021-01-22 02:18:40","TRTEDTM":"2024-01-22 20:18:40","TRT01SDTM":"2021-01-22 02:18:40","TRT01EDTM":"2023-01-22 14:18:40","TRT02SDTM":"2023-01-22 14:18:40","TRT02EDTM":"2024-01-22 20:18:40","AP01SDTM":"2021-01-22 02:18:40","AP01EDTM":"2023-01-22 14:18:40","AP02SDTM":"2023-01-22 14:18:40","AP02EDTM":"2024-01-22 20:18:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-22","EOSDY":1096,"LSTALVDT":"2024-02-20","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":692,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05149,"AVALU":"g/L","BASE2":2.96239,"BASE":2.88135,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08911,"PCHG2":3.00799,"CHG":0.17015,"PCHG":5.90517,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2023-04-01 02:18:40","ADY":799,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-2-id-296","SUBJID":"id-296","SITEID":"BRA-2","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-2","INVNAM":"Dr. BRA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.75083,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-19","TRTSDTM":"2021-01-22 02:18:40","TRTEDTM":"2024-01-22 20:18:40","TRT01SDTM":"2021-01-22 02:18:40","TRT01EDTM":"2023-01-22 14:18:40","TRT02SDTM":"2023-01-22 14:18:40","TRT02EDTM":"2024-01-22 20:18:40","AP01SDTM":"2021-01-22 02:18:40","AP01EDTM":"2023-01-22 14:18:40","AP02SDTM":"2023-01-22 14:18:40","AP02EDTM":"2024-01-22 20:18:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-22","EOSDY":1096,"LSTALVDT":"2024-02-20","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6022,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88432,"AVALU":"g/L","BASE2":2.96239,"BASE":2.88135,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07807,"PCHG2":-2.63535,"CHG":0.00297,"PCHG":0.10311,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-25 02:18:40","ADY":914,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-13","SUBJID":"id-13","SITEID":"BRA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.88873,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-20","TRTSDTM":"2020-04-24 22:49:58","TRTEDTM":"2023-04-25 16:49:58","TRT01SDTM":"2020-04-24 22:49:58","TRT01EDTM":"2022-04-25 10:49:58","TRT02SDTM":"2022-04-25 10:49:58","TRT02EDTM":"2023-04-25 16:49:58","AP01SDTM":"2020-04-24 22:49:58","AP01EDTM":"2022-04-25 10:49:58","AP02SDTM":"2022-04-25 10:49:58","AP02EDTM":"2023-04-25 16:49:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-25","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2222,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.21292,"AVALU":"U/L","BASE2":9.21292,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-01 22:49:58","ADY":38,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-13","SUBJID":"id-13","SITEID":"BRA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.88873,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-20","TRTSDTM":"2020-04-24 22:49:58","TRTEDTM":"2023-04-25 16:49:58","TRT01SDTM":"2020-04-24 22:49:58","TRT01EDTM":"2022-04-25 10:49:58","TRT02SDTM":"2022-04-25 10:49:58","TRT02EDTM":"2023-04-25 16:49:58","AP01SDTM":"2020-04-24 22:49:58","AP01EDTM":"2022-04-25 10:49:58","AP02SDTM":"2022-04-25 10:49:58","AP02EDTM":"2023-04-25 16:49:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-25","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2289,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.5709,"AVALU":"U/L","BASE2":9.21292,"BASE":22.5709,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":13.35797,"PCHG2":144.99169,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-15 22:49:58","ADY":113,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-13","SUBJID":"id-13","SITEID":"BRA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.88873,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-20","TRTSDTM":"2020-04-24 22:49:58","TRTEDTM":"2023-04-25 16:49:58","TRT01SDTM":"2020-04-24 22:49:58","TRT01EDTM":"2022-04-25 10:49:58","TRT02SDTM":"2022-04-25 10:49:58","TRT02EDTM":"2023-04-25 16:49:58","AP01SDTM":"2020-04-24 22:49:58","AP01EDTM":"2022-04-25 10:49:58","AP02SDTM":"2022-04-25 10:49:58","AP02EDTM":"2023-04-25 16:49:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-25","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3875,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.72346,"AVALU":"U/L","BASE2":9.21292,"BASE":22.5709,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.51054,"PCHG2":16.39588,"CHG":-11.84743,"PCHG":-52.48987,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-11 22:49:58","ADY":352,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-13","SUBJID":"id-13","SITEID":"BRA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.88873,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-20","TRTSDTM":"2020-04-24 22:49:58","TRTEDTM":"2023-04-25 16:49:58","TRT01SDTM":"2020-04-24 22:49:58","TRT01EDTM":"2022-04-25 10:49:58","TRT02SDTM":"2022-04-25 10:49:58","TRT02EDTM":"2023-04-25 16:49:58","AP01SDTM":"2020-04-24 22:49:58","AP01EDTM":"2022-04-25 10:49:58","AP02SDTM":"2022-04-25 10:49:58","AP02EDTM":"2023-04-25 16:49:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-25","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3601,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.87853,"AVALU":"U/L","BASE2":9.21292,"BASE":22.5709,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.33439,"PCHG2":-68.75552,"CHG":-19.69237,"PCHG":-87.24672,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-06-29 22:49:58","ADY":431,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-13","SUBJID":"id-13","SITEID":"BRA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.88873,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-20","TRTSDTM":"2020-04-24 22:49:58","TRTEDTM":"2023-04-25 16:49:58","TRT01SDTM":"2020-04-24 22:49:58","TRT01EDTM":"2022-04-25 10:49:58","TRT02SDTM":"2022-04-25 10:49:58","TRT02EDTM":"2023-04-25 16:49:58","AP01SDTM":"2020-04-24 22:49:58","AP01EDTM":"2022-04-25 10:49:58","AP02SDTM":"2022-04-25 10:49:58","AP02EDTM":"2023-04-25 16:49:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-25","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":645,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":35.07815,"AVALU":"U/L","BASE2":9.21292,"BASE":22.5709,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":25.86522,"PCHG2":280.74935,"CHG":12.50725,"PCHG":55.41317,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-15 22:49:58","ADY":843,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-13","SUBJID":"id-13","SITEID":"BRA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.88873,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-20","TRTSDTM":"2020-04-24 22:49:58","TRTEDTM":"2023-04-25 16:49:58","TRT01SDTM":"2020-04-24 22:49:58","TRT01EDTM":"2022-04-25 10:49:58","TRT02SDTM":"2022-04-25 10:49:58","TRT02EDTM":"2023-04-25 16:49:58","AP01SDTM":"2020-04-24 22:49:58","AP01EDTM":"2022-04-25 10:49:58","AP02SDTM":"2022-04-25 10:49:58","AP02EDTM":"2023-04-25 16:49:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-25","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8135,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.47707,"AVALU":"U/L","BASE2":9.21292,"BASE":22.5709,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.26415,"PCHG2":13.72149,"CHG":-12.09382,"PCHG":-53.58149,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-16 22:49:58","ADY":844,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-13","SUBJID":"id-13","SITEID":"BRA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.88873,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-20","TRTSDTM":"2020-04-24 22:49:58","TRTEDTM":"2023-04-25 16:49:58","TRT01SDTM":"2020-04-24 22:49:58","TRT01EDTM":"2022-04-25 10:49:58","TRT02SDTM":"2022-04-25 10:49:58","TRT02EDTM":"2023-04-25 16:49:58","AP01SDTM":"2020-04-24 22:49:58","AP01EDTM":"2022-04-25 10:49:58","AP02SDTM":"2022-04-25 10:49:58","AP02EDTM":"2023-04-25 16:49:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-25","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2196,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.1487,"AVALU":"U/L","BASE2":9.21292,"BASE":22.5709,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.93578,"PCHG2":216.38923,"CHG":6.5778,"PCHG":29.14284,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-18 22:49:58","ADY":877,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-13","SUBJID":"id-13","SITEID":"BRA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.88873,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-20","TRTSDTM":"2020-04-24 22:49:58","TRTEDTM":"2023-04-25 16:49:58","TRT01SDTM":"2020-04-24 22:49:58","TRT01EDTM":"2022-04-25 10:49:58","TRT02SDTM":"2022-04-25 10:49:58","TRT02EDTM":"2023-04-25 16:49:58","AP01SDTM":"2020-04-24 22:49:58","AP01EDTM":"2022-04-25 10:49:58","AP02SDTM":"2022-04-25 10:49:58","AP02EDTM":"2023-04-25 16:49:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-25","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8131,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.6892,"AVALU":"mg/L","BASE2":8.6892,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-06-01 22:49:58","ADY":38,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-13","SUBJID":"id-13","SITEID":"BRA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.88873,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-20","TRTSDTM":"2020-04-24 22:49:58","TRTEDTM":"2023-04-25 16:49:58","TRT01SDTM":"2020-04-24 22:49:58","TRT01EDTM":"2022-04-25 10:49:58","TRT02SDTM":"2022-04-25 10:49:58","TRT02EDTM":"2023-04-25 16:49:58","AP01SDTM":"2020-04-24 22:49:58","AP01EDTM":"2022-04-25 10:49:58","AP02SDTM":"2022-04-25 10:49:58","AP02EDTM":"2023-04-25 16:49:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-25","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4632,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.19237,"AVALU":"mg/L","BASE2":8.6892,"BASE":7.19237,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.49683,"PCHG2":-17.22631,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2020-08-15 22:49:58","ADY":113,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-13","SUBJID":"id-13","SITEID":"BRA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.88873,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-20","TRTSDTM":"2020-04-24 22:49:58","TRTEDTM":"2023-04-25 16:49:58","TRT01SDTM":"2020-04-24 22:49:58","TRT01EDTM":"2022-04-25 10:49:58","TRT02SDTM":"2022-04-25 10:49:58","TRT02EDTM":"2023-04-25 16:49:58","AP01SDTM":"2020-04-24 22:49:58","AP01EDTM":"2022-04-25 10:49:58","AP02SDTM":"2022-04-25 10:49:58","AP02EDTM":"2023-04-25 16:49:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-25","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3527,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.10457,"AVALU":"mg/L","BASE2":8.6892,"BASE":7.19237,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.58463,"PCHG2":-6.72825,"CHG":0.9122,"PCHG":12.68284,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-04-11 22:49:58","ADY":352,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-13","SUBJID":"id-13","SITEID":"BRA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.88873,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-20","TRTSDTM":"2020-04-24 22:49:58","TRTEDTM":"2023-04-25 16:49:58","TRT01SDTM":"2020-04-24 22:49:58","TRT01EDTM":"2022-04-25 10:49:58","TRT02SDTM":"2022-04-25 10:49:58","TRT02EDTM":"2023-04-25 16:49:58","AP01SDTM":"2020-04-24 22:49:58","AP01EDTM":"2022-04-25 10:49:58","AP02SDTM":"2022-04-25 10:49:58","AP02EDTM":"2023-04-25 16:49:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-25","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1521,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.43521,"AVALU":"mg/L","BASE2":8.6892,"BASE":7.19237,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.74602,"PCHG2":20.0941,"CHG":3.24284,"PCHG":45.08729,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"2","BTOXGR":"-1","ADTM":"2021-06-29 22:49:58","ADY":431,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-13","SUBJID":"id-13","SITEID":"BRA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.88873,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-20","TRTSDTM":"2020-04-24 22:49:58","TRTEDTM":"2023-04-25 16:49:58","TRT01SDTM":"2020-04-24 22:49:58","TRT01EDTM":"2022-04-25 10:49:58","TRT02SDTM":"2022-04-25 10:49:58","TRT02EDTM":"2023-04-25 16:49:58","AP01SDTM":"2020-04-24 22:49:58","AP01EDTM":"2022-04-25 10:49:58","AP02SDTM":"2022-04-25 10:49:58","AP02EDTM":"2023-04-25 16:49:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-25","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4861,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.24811,"AVALU":"mg/L","BASE2":8.6892,"BASE":7.19237,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.44109,"PCHG2":-16.58486,"CHG":0.05574,"PCHG":0.77495,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-2","BTOXGR":"-1","ADTM":"2022-08-15 22:49:58","ADY":843,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-13","SUBJID":"id-13","SITEID":"BRA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.88873,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-20","TRTSDTM":"2020-04-24 22:49:58","TRTEDTM":"2023-04-25 16:49:58","TRT01SDTM":"2020-04-24 22:49:58","TRT01EDTM":"2022-04-25 10:49:58","TRT02SDTM":"2022-04-25 10:49:58","TRT02EDTM":"2023-04-25 16:49:58","AP01SDTM":"2020-04-24 22:49:58","AP01EDTM":"2022-04-25 10:49:58","AP02SDTM":"2022-04-25 10:49:58","AP02EDTM":"2023-04-25 16:49:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-25","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5525,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.878,"AVALU":"mg/L","BASE2":8.6892,"BASE":7.19237,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1888,"PCHG2":2.17286,"CHG":1.68563,"PCHG":23.4364,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-08-16 22:49:58","ADY":844,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-13","SUBJID":"id-13","SITEID":"BRA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.88873,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-20","TRTSDTM":"2020-04-24 22:49:58","TRTEDTM":"2023-04-25 16:49:58","TRT01SDTM":"2020-04-24 22:49:58","TRT01EDTM":"2022-04-25 10:49:58","TRT02SDTM":"2022-04-25 10:49:58","TRT02EDTM":"2023-04-25 16:49:58","AP01SDTM":"2020-04-24 22:49:58","AP01EDTM":"2022-04-25 10:49:58","AP02SDTM":"2022-04-25 10:49:58","AP02EDTM":"2023-04-25 16:49:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-25","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3555,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.30677,"AVALU":"mg/L","BASE2":8.6892,"BASE":7.19237,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.38242,"PCHG2":-4.40115,"CHG":1.1144,"PCHG":15.49425,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-09-18 22:49:58","ADY":877,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-13","SUBJID":"id-13","SITEID":"BRA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.88873,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-20","TRTSDTM":"2020-04-24 22:49:58","TRTEDTM":"2023-04-25 16:49:58","TRT01SDTM":"2020-04-24 22:49:58","TRT01EDTM":"2022-04-25 10:49:58","TRT02SDTM":"2022-04-25 10:49:58","TRT02EDTM":"2023-04-25 16:49:58","AP01SDTM":"2020-04-24 22:49:58","AP01EDTM":"2022-04-25 10:49:58","AP02SDTM":"2022-04-25 10:49:58","AP02EDTM":"2023-04-25 16:49:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-25","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4307,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9253,"AVALU":"g/L","BASE2":2.9253,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-01 22:49:58","ADY":38,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-13","SUBJID":"id-13","SITEID":"BRA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.88873,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-20","TRTSDTM":"2020-04-24 22:49:58","TRTEDTM":"2023-04-25 16:49:58","TRT01SDTM":"2020-04-24 22:49:58","TRT01EDTM":"2022-04-25 10:49:58","TRT02SDTM":"2022-04-25 10:49:58","TRT02EDTM":"2023-04-25 16:49:58","AP01SDTM":"2020-04-24 22:49:58","AP01EDTM":"2022-04-25 10:49:58","AP02SDTM":"2022-04-25 10:49:58","AP02EDTM":"2023-04-25 16:49:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-25","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":423,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74024,"AVALU":"g/L","BASE2":2.9253,"BASE":2.74024,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.18506,"PCHG2":-6.32634,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-15 22:49:58","ADY":113,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-13","SUBJID":"id-13","SITEID":"BRA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.88873,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-20","TRTSDTM":"2020-04-24 22:49:58","TRTEDTM":"2023-04-25 16:49:58","TRT01SDTM":"2020-04-24 22:49:58","TRT01EDTM":"2022-04-25 10:49:58","TRT02SDTM":"2022-04-25 10:49:58","TRT02EDTM":"2023-04-25 16:49:58","AP01SDTM":"2020-04-24 22:49:58","AP01EDTM":"2022-04-25 10:49:58","AP02SDTM":"2022-04-25 10:49:58","AP02EDTM":"2023-04-25 16:49:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-25","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5457,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95258,"AVALU":"g/L","BASE2":2.9253,"BASE":2.74024,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02728,"PCHG2":0.93263,"CHG":0.21235,"PCHG":7.74921,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-11 22:49:58","ADY":352,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-13","SUBJID":"id-13","SITEID":"BRA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.88873,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-20","TRTSDTM":"2020-04-24 22:49:58","TRTEDTM":"2023-04-25 16:49:58","TRT01SDTM":"2020-04-24 22:49:58","TRT01EDTM":"2022-04-25 10:49:58","TRT02SDTM":"2022-04-25 10:49:58","TRT02EDTM":"2023-04-25 16:49:58","AP01SDTM":"2020-04-24 22:49:58","AP01EDTM":"2022-04-25 10:49:58","AP02SDTM":"2022-04-25 10:49:58","AP02EDTM":"2023-04-25 16:49:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-25","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3898,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88833,"AVALU":"g/L","BASE2":2.9253,"BASE":2.74024,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03698,"PCHG2":-1.26399,"CHG":0.14809,"PCHG":5.40424,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-29 22:49:58","ADY":431,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-13","SUBJID":"id-13","SITEID":"BRA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.88873,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-20","TRTSDTM":"2020-04-24 22:49:58","TRTEDTM":"2023-04-25 16:49:58","TRT01SDTM":"2020-04-24 22:49:58","TRT01EDTM":"2022-04-25 10:49:58","TRT02SDTM":"2022-04-25 10:49:58","TRT02EDTM":"2023-04-25 16:49:58","AP01SDTM":"2020-04-24 22:49:58","AP01EDTM":"2022-04-25 10:49:58","AP02SDTM":"2022-04-25 10:49:58","AP02EDTM":"2023-04-25 16:49:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-25","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2494,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92932,"AVALU":"g/L","BASE2":2.9253,"BASE":2.74024,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00402,"PCHG2":0.13725,"CHG":0.18908,"PCHG":6.90012,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-15 22:49:58","ADY":843,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-13","SUBJID":"id-13","SITEID":"BRA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.88873,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-20","TRTSDTM":"2020-04-24 22:49:58","TRTEDTM":"2023-04-25 16:49:58","TRT01SDTM":"2020-04-24 22:49:58","TRT01EDTM":"2022-04-25 10:49:58","TRT02SDTM":"2022-04-25 10:49:58","TRT02EDTM":"2023-04-25 16:49:58","AP01SDTM":"2020-04-24 22:49:58","AP01EDTM":"2022-04-25 10:49:58","AP02SDTM":"2022-04-25 10:49:58","AP02EDTM":"2023-04-25 16:49:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-25","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1271,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95739,"AVALU":"g/L","BASE2":2.9253,"BASE":2.74024,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03209,"PCHG2":1.09695,"CHG":0.21715,"PCHG":7.92464,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-16 22:49:58","ADY":844,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-13","SUBJID":"id-13","SITEID":"BRA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.88873,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-20","TRTSDTM":"2020-04-24 22:49:58","TRTEDTM":"2023-04-25 16:49:58","TRT01SDTM":"2020-04-24 22:49:58","TRT01EDTM":"2022-04-25 10:49:58","TRT02SDTM":"2022-04-25 10:49:58","TRT02EDTM":"2023-04-25 16:49:58","AP01SDTM":"2020-04-24 22:49:58","AP01EDTM":"2022-04-25 10:49:58","AP02SDTM":"2022-04-25 10:49:58","AP02EDTM":"2023-04-25 16:49:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-25","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3524,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94752,"AVALU":"g/L","BASE2":2.9253,"BASE":2.74024,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02222,"PCHG2":0.7597,"CHG":0.20729,"PCHG":7.56461,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-18 22:49:58","ADY":877,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-8","SUBJID":"id-8","SITEID":"BRA-3","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":0.64837,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 23:40:59","TRTEDTM":"2022-02-17 03:14:20","TRT01SDTM":"2020-03-12 23:40:59","TRT01EDTM":"2021-02-16 21:14:20","TRT02SDTM":"2021-02-16 21:14:20","TRT02EDTM":"2022-02-17 03:14:20","AP01SDTM":"2020-03-12 23:40:59","AP01EDTM":"2021-02-16 21:14:20","AP02SDTM":"2021-02-16 21:14:20","AP02EDTM":"2022-02-17 03:14:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":707,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-10","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6807,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.66782,"AVALU":"U/L","BASE2":0.66782,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-04-24 23:40:59","ADY":43,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-8","SUBJID":"id-8","SITEID":"BRA-3","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":0.64837,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 23:40:59","TRTEDTM":"2022-02-17 03:14:20","TRT01SDTM":"2020-03-12 23:40:59","TRT01EDTM":"2021-02-16 21:14:20","TRT02SDTM":"2021-02-16 21:14:20","TRT02EDTM":"2022-02-17 03:14:20","AP01SDTM":"2020-03-12 23:40:59","AP01EDTM":"2021-02-16 21:14:20","AP02SDTM":"2021-02-16 21:14:20","AP02EDTM":"2022-02-17 03:14:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":707,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-10","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4029,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.79056,"AVALU":"U/L","BASE2":0.66782,"BASE":27.79056,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":27.12275,"PCHG2":4061.41033,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-16 23:40:59","ADY":96,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-8","SUBJID":"id-8","SITEID":"BRA-3","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":0.64837,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 23:40:59","TRTEDTM":"2022-02-17 03:14:20","TRT01SDTM":"2020-03-12 23:40:59","TRT01EDTM":"2021-02-16 21:14:20","TRT02SDTM":"2021-02-16 21:14:20","TRT02EDTM":"2022-02-17 03:14:20","AP01SDTM":"2020-03-12 23:40:59","AP01EDTM":"2021-02-16 21:14:20","AP02SDTM":"2021-02-16 21:14:20","AP02EDTM":"2022-02-17 03:14:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":707,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-10","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5735,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.0304,"AVALU":"U/L","BASE2":0.66782,"BASE":27.79056,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":22.36258,"PCHG2":3348.61478,"CHG":-4.76016,"PCHG":-17.1287,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-16 23:40:59","ADY":188,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-8","SUBJID":"id-8","SITEID":"BRA-3","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":0.64837,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 23:40:59","TRTEDTM":"2022-02-17 03:14:20","TRT01SDTM":"2020-03-12 23:40:59","TRT01EDTM":"2021-02-16 21:14:20","TRT02SDTM":"2021-02-16 21:14:20","TRT02EDTM":"2022-02-17 03:14:20","AP01SDTM":"2020-03-12 23:40:59","AP01EDTM":"2021-02-16 21:14:20","AP02SDTM":"2021-02-16 21:14:20","AP02EDTM":"2022-02-17 03:14:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":707,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-10","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7779,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.62651,"AVALU":"U/L","BASE2":0.66782,"BASE":27.79056,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.95869,"PCHG2":592.78159,"CHG":-23.16406,"PCHG":-83.35224,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-09-21 23:40:59","ADY":193,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-8","SUBJID":"id-8","SITEID":"BRA-3","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":0.64837,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 23:40:59","TRTEDTM":"2022-02-17 03:14:20","TRT01SDTM":"2020-03-12 23:40:59","TRT01EDTM":"2021-02-16 21:14:20","TRT02SDTM":"2021-02-16 21:14:20","TRT02EDTM":"2022-02-17 03:14:20","AP01SDTM":"2020-03-12 23:40:59","AP01EDTM":"2021-02-16 21:14:20","AP02SDTM":"2021-02-16 21:14:20","AP02EDTM":"2022-02-17 03:14:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":707,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-10","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":826,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.42819,"AVALU":"U/L","BASE2":0.66782,"BASE":27.79056,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":20.76037,"PCHG2":3108.69662,"CHG":-6.36237,"PCHG":-22.89401,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-06 23:40:59","ADY":239,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-8","SUBJID":"id-8","SITEID":"BRA-3","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":0.64837,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 23:40:59","TRTEDTM":"2022-02-17 03:14:20","TRT01SDTM":"2020-03-12 23:40:59","TRT01EDTM":"2021-02-16 21:14:20","TRT02SDTM":"2021-02-16 21:14:20","TRT02EDTM":"2022-02-17 03:14:20","AP01SDTM":"2020-03-12 23:40:59","AP01EDTM":"2021-02-16 21:14:20","AP02SDTM":"2021-02-16 21:14:20","AP02EDTM":"2022-02-17 03:14:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":707,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-10","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7968,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.42816,"AVALU":"U/L","BASE2":0.66782,"BASE":27.79056,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":22.76034,"PCHG2":3408.17601,"CHG":-4.3624,"PCHG":-15.69743,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-12 23:40:59","ADY":396,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-8","SUBJID":"id-8","SITEID":"BRA-3","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":0.64837,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 23:40:59","TRTEDTM":"2022-02-17 03:14:20","TRT01SDTM":"2020-03-12 23:40:59","TRT01EDTM":"2021-02-16 21:14:20","TRT02SDTM":"2021-02-16 21:14:20","TRT02EDTM":"2022-02-17 03:14:20","AP01SDTM":"2020-03-12 23:40:59","AP01EDTM":"2021-02-16 21:14:20","AP02SDTM":"2021-02-16 21:14:20","AP02EDTM":"2022-02-17 03:14:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":707,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-10","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2649,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.6534,"AVALU":"U/L","BASE2":0.66782,"BASE":27.79056,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.98558,"PCHG2":2543.45256,"CHG":-10.13716,"PCHG":-36.477,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-07 23:40:59","ADY":452,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-8","SUBJID":"id-8","SITEID":"BRA-3","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":0.64837,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 23:40:59","TRTEDTM":"2022-02-17 03:14:20","TRT01SDTM":"2020-03-12 23:40:59","TRT01EDTM":"2021-02-16 21:14:20","TRT02SDTM":"2021-02-16 21:14:20","TRT02EDTM":"2022-02-17 03:14:20","AP01SDTM":"2020-03-12 23:40:59","AP01EDTM":"2021-02-16 21:14:20","AP02SDTM":"2021-02-16 21:14:20","AP02EDTM":"2022-02-17 03:14:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":707,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-10","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4055,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.26278,"AVALU":"mg/L","BASE2":8.26278,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-24 23:40:59","ADY":43,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-8","SUBJID":"id-8","SITEID":"BRA-3","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":0.64837,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 23:40:59","TRTEDTM":"2022-02-17 03:14:20","TRT01SDTM":"2020-03-12 23:40:59","TRT01EDTM":"2021-02-16 21:14:20","TRT02SDTM":"2021-02-16 21:14:20","TRT02EDTM":"2022-02-17 03:14:20","AP01SDTM":"2020-03-12 23:40:59","AP01EDTM":"2021-02-16 21:14:20","AP02SDTM":"2021-02-16 21:14:20","AP02EDTM":"2022-02-17 03:14:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":707,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-10","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8243,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.76571,"AVALU":"mg/L","BASE2":8.26278,"BASE":9.76571,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.50294,"PCHG2":18.18927,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-16 23:40:59","ADY":96,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-8","SUBJID":"id-8","SITEID":"BRA-3","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":0.64837,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 23:40:59","TRTEDTM":"2022-02-17 03:14:20","TRT01SDTM":"2020-03-12 23:40:59","TRT01EDTM":"2021-02-16 21:14:20","TRT02SDTM":"2021-02-16 21:14:20","TRT02EDTM":"2022-02-17 03:14:20","AP01SDTM":"2020-03-12 23:40:59","AP01EDTM":"2021-02-16 21:14:20","AP02SDTM":"2021-02-16 21:14:20","AP02EDTM":"2022-02-17 03:14:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":707,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-10","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8393,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.12855,"AVALU":"mg/L","BASE2":8.26278,"BASE":9.76571,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.86577,"PCHG2":22.58044,"CHG":0.36283,"PCHG":3.71537,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-09-16 23:40:59","ADY":188,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-8","SUBJID":"id-8","SITEID":"BRA-3","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":0.64837,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 23:40:59","TRTEDTM":"2022-02-17 03:14:20","TRT01SDTM":"2020-03-12 23:40:59","TRT01EDTM":"2021-02-16 21:14:20","TRT02SDTM":"2021-02-16 21:14:20","TRT02EDTM":"2022-02-17 03:14:20","AP01SDTM":"2020-03-12 23:40:59","AP01EDTM":"2021-02-16 21:14:20","AP02SDTM":"2021-02-16 21:14:20","AP02EDTM":"2022-02-17 03:14:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":707,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-10","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":581,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.0336,"AVALU":"mg/L","BASE2":8.26278,"BASE":9.76571,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.22917,"PCHG2":-14.87605,"CHG":-2.73211,"PCHG":-27.97658,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-09-21 23:40:59","ADY":193,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-8","SUBJID":"id-8","SITEID":"BRA-3","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":0.64837,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 23:40:59","TRTEDTM":"2022-02-17 03:14:20","TRT01SDTM":"2020-03-12 23:40:59","TRT01EDTM":"2021-02-16 21:14:20","TRT02SDTM":"2021-02-16 21:14:20","TRT02EDTM":"2022-02-17 03:14:20","AP01SDTM":"2020-03-12 23:40:59","AP01EDTM":"2021-02-16 21:14:20","AP02SDTM":"2021-02-16 21:14:20","AP02EDTM":"2022-02-17 03:14:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":707,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-10","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1677,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.36151,"AVALU":"mg/L","BASE2":8.26278,"BASE":9.76571,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09873,"PCHG2":1.19491,"CHG":-1.40421,"PCHG":-14.37893,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-06 23:40:59","ADY":239,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-8","SUBJID":"id-8","SITEID":"BRA-3","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":0.64837,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 23:40:59","TRTEDTM":"2022-02-17 03:14:20","TRT01SDTM":"2020-03-12 23:40:59","TRT01EDTM":"2021-02-16 21:14:20","TRT02SDTM":"2021-02-16 21:14:20","TRT02EDTM":"2022-02-17 03:14:20","AP01SDTM":"2020-03-12 23:40:59","AP01EDTM":"2021-02-16 21:14:20","AP02SDTM":"2021-02-16 21:14:20","AP02EDTM":"2022-02-17 03:14:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":707,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-10","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7478,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.42275,"AVALU":"mg/L","BASE2":8.26278,"BASE":9.76571,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.84002,"PCHG2":-22.26883,"CHG":-3.34296,"PCHG":-34.23162,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-04-12 23:40:59","ADY":396,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-8","SUBJID":"id-8","SITEID":"BRA-3","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":0.64837,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 23:40:59","TRTEDTM":"2022-02-17 03:14:20","TRT01SDTM":"2020-03-12 23:40:59","TRT01EDTM":"2021-02-16 21:14:20","TRT02SDTM":"2021-02-16 21:14:20","TRT02EDTM":"2022-02-17 03:14:20","AP01SDTM":"2020-03-12 23:40:59","AP01EDTM":"2021-02-16 21:14:20","AP02SDTM":"2021-02-16 21:14:20","AP02EDTM":"2022-02-17 03:14:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":707,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-10","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8138,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.0148,"AVALU":"mg/L","BASE2":8.26278,"BASE":9.76571,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.24797,"PCHG2":-3.00108,"CHG":-1.75091,"PCHG":-17.92916,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-07 23:40:59","ADY":452,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-8","SUBJID":"id-8","SITEID":"BRA-3","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":0.64837,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 23:40:59","TRTEDTM":"2022-02-17 03:14:20","TRT01SDTM":"2020-03-12 23:40:59","TRT01EDTM":"2021-02-16 21:14:20","TRT02SDTM":"2021-02-16 21:14:20","TRT02EDTM":"2022-02-17 03:14:20","AP01SDTM":"2020-03-12 23:40:59","AP01EDTM":"2021-02-16 21:14:20","AP02SDTM":"2021-02-16 21:14:20","AP02EDTM":"2022-02-17 03:14:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":707,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-10","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5412,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95865,"AVALU":"g/L","BASE2":2.95865,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-24 23:40:59","ADY":43,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-8","SUBJID":"id-8","SITEID":"BRA-3","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":0.64837,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 23:40:59","TRTEDTM":"2022-02-17 03:14:20","TRT01SDTM":"2020-03-12 23:40:59","TRT01EDTM":"2021-02-16 21:14:20","TRT02SDTM":"2021-02-16 21:14:20","TRT02EDTM":"2022-02-17 03:14:20","AP01SDTM":"2020-03-12 23:40:59","AP01EDTM":"2021-02-16 21:14:20","AP02SDTM":"2021-02-16 21:14:20","AP02EDTM":"2022-02-17 03:14:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":707,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-10","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1525,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83412,"AVALU":"g/L","BASE2":2.95865,"BASE":2.83412,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.12454,"PCHG2":-4.20919,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-16 23:40:59","ADY":96,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-8","SUBJID":"id-8","SITEID":"BRA-3","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":0.64837,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 23:40:59","TRTEDTM":"2022-02-17 03:14:20","TRT01SDTM":"2020-03-12 23:40:59","TRT01EDTM":"2021-02-16 21:14:20","TRT02SDTM":"2021-02-16 21:14:20","TRT02EDTM":"2022-02-17 03:14:20","AP01SDTM":"2020-03-12 23:40:59","AP01EDTM":"2021-02-16 21:14:20","AP02SDTM":"2021-02-16 21:14:20","AP02EDTM":"2022-02-17 03:14:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":707,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-10","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7456,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.70908,"AVALU":"g/L","BASE2":2.95865,"BASE":2.83412,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.24957,"PCHG2":-8.43516,"CHG":-0.12503,"PCHG":-4.41166,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-16 23:40:59","ADY":188,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-8","SUBJID":"id-8","SITEID":"BRA-3","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":0.64837,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 23:40:59","TRTEDTM":"2022-02-17 03:14:20","TRT01SDTM":"2020-03-12 23:40:59","TRT01EDTM":"2021-02-16 21:14:20","TRT02SDTM":"2021-02-16 21:14:20","TRT02EDTM":"2022-02-17 03:14:20","AP01SDTM":"2020-03-12 23:40:59","AP01EDTM":"2021-02-16 21:14:20","AP02SDTM":"2021-02-16 21:14:20","AP02EDTM":"2022-02-17 03:14:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":707,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-10","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6894,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99297,"AVALU":"g/L","BASE2":2.95865,"BASE":2.83412,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03432,"PCHG2":1.15997,"CHG":0.15885,"PCHG":5.60508,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-21 23:40:59","ADY":193,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-8","SUBJID":"id-8","SITEID":"BRA-3","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":0.64837,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 23:40:59","TRTEDTM":"2022-02-17 03:14:20","TRT01SDTM":"2020-03-12 23:40:59","TRT01EDTM":"2021-02-16 21:14:20","TRT02SDTM":"2021-02-16 21:14:20","TRT02EDTM":"2022-02-17 03:14:20","AP01SDTM":"2020-03-12 23:40:59","AP01EDTM":"2021-02-16 21:14:20","AP02SDTM":"2021-02-16 21:14:20","AP02EDTM":"2022-02-17 03:14:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":707,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-10","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1084,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86146,"AVALU":"g/L","BASE2":2.95865,"BASE":2.83412,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09719,"PCHG2":-3.28488,"CHG":0.02735,"PCHG":0.96493,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-06 23:40:59","ADY":239,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-8","SUBJID":"id-8","SITEID":"BRA-3","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":0.64837,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 23:40:59","TRTEDTM":"2022-02-17 03:14:20","TRT01SDTM":"2020-03-12 23:40:59","TRT01EDTM":"2021-02-16 21:14:20","TRT02SDTM":"2021-02-16 21:14:20","TRT02EDTM":"2022-02-17 03:14:20","AP01SDTM":"2020-03-12 23:40:59","AP01EDTM":"2021-02-16 21:14:20","AP02SDTM":"2021-02-16 21:14:20","AP02EDTM":"2022-02-17 03:14:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":707,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-10","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7742,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79767,"AVALU":"g/L","BASE2":2.95865,"BASE":2.83412,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16098,"PCHG2":-5.44097,"CHG":-0.03644,"PCHG":-1.2859,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-12 23:40:59","ADY":396,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-3-id-8","SUBJID":"id-8","SITEID":"BRA-3","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-3","INVNAM":"Dr. BRA-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":0.64837,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 23:40:59","TRTEDTM":"2022-02-17 03:14:20","TRT01SDTM":"2020-03-12 23:40:59","TRT01EDTM":"2021-02-16 21:14:20","TRT02SDTM":"2021-02-16 21:14:20","TRT02EDTM":"2022-02-17 03:14:20","AP01SDTM":"2020-03-12 23:40:59","AP01EDTM":"2021-02-16 21:14:20","AP02SDTM":"2021-02-16 21:14:20","AP02EDTM":"2022-02-17 03:14:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":707,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-10","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1841,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01709,"AVALU":"g/L","BASE2":2.95865,"BASE":2.83412,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05843,"PCHG2":1.97504,"CHG":0.18297,"PCHG":6.45598,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-06-07 23:40:59","ADY":452,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-368","SUBJID":"id-368","SITEID":"BRA-4","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.20454,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-25 19:46:04","TRTEDTM":"2023-02-25 13:46:04","TRT01SDTM":"2020-02-25 19:46:04","TRT01EDTM":"2022-02-25 07:46:04","TRT02SDTM":"2022-02-25 07:46:04","TRT02EDTM":"2023-02-25 13:46:04","AP01SDTM":"2020-02-25 19:46:04","AP01EDTM":"2022-02-25 07:46:04","AP02SDTM":"2022-02-25 07:46:04","AP02EDTM":"2023-02-25 13:46:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-19","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8391,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.67066,"AVALU":"U/L","BASE2":24.67066,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-23 19:46:04","ADY":211,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-368","SUBJID":"id-368","SITEID":"BRA-4","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.20454,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-25 19:46:04","TRTEDTM":"2023-02-25 13:46:04","TRT01SDTM":"2020-02-25 19:46:04","TRT01EDTM":"2022-02-25 07:46:04","TRT02SDTM":"2022-02-25 07:46:04","TRT02EDTM":"2023-02-25 13:46:04","AP01SDTM":"2020-02-25 19:46:04","AP01EDTM":"2022-02-25 07:46:04","AP02SDTM":"2022-02-25 07:46:04","AP02EDTM":"2023-02-25 13:46:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-19","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1018,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.69911,"AVALU":"U/L","BASE2":24.67066,"BASE":21.69911,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.97155,"PCHG2":-12.04488,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-29 19:46:04","ADY":217,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-368","SUBJID":"id-368","SITEID":"BRA-4","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.20454,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-25 19:46:04","TRTEDTM":"2023-02-25 13:46:04","TRT01SDTM":"2020-02-25 19:46:04","TRT01EDTM":"2022-02-25 07:46:04","TRT02SDTM":"2022-02-25 07:46:04","TRT02EDTM":"2023-02-25 13:46:04","AP01SDTM":"2020-02-25 19:46:04","AP01EDTM":"2022-02-25 07:46:04","AP02SDTM":"2022-02-25 07:46:04","AP02EDTM":"2023-02-25 13:46:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-19","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":431,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.67329,"AVALU":"U/L","BASE2":24.67066,"BASE":21.69911,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.99737,"PCHG2":-20.25632,"CHG":-2.02582,"PCHG":-9.33594,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-16 19:46:04","ADY":446,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-368","SUBJID":"id-368","SITEID":"BRA-4","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.20454,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-25 19:46:04","TRTEDTM":"2023-02-25 13:46:04","TRT01SDTM":"2020-02-25 19:46:04","TRT01EDTM":"2022-02-25 07:46:04","TRT02SDTM":"2022-02-25 07:46:04","TRT02EDTM":"2023-02-25 13:46:04","AP01SDTM":"2020-02-25 19:46:04","AP01EDTM":"2022-02-25 07:46:04","AP02SDTM":"2022-02-25 07:46:04","AP02EDTM":"2023-02-25 13:46:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-19","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3388,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.31164,"AVALU":"U/L","BASE2":24.67066,"BASE":21.69911,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.35902,"PCHG2":-25.77564,"CHG":-3.38747,"PCHG":-15.6111,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-07 19:46:04","ADY":590,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-368","SUBJID":"id-368","SITEID":"BRA-4","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.20454,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-25 19:46:04","TRTEDTM":"2023-02-25 13:46:04","TRT01SDTM":"2020-02-25 19:46:04","TRT01EDTM":"2022-02-25 07:46:04","TRT02SDTM":"2022-02-25 07:46:04","TRT02EDTM":"2023-02-25 13:46:04","AP01SDTM":"2020-02-25 19:46:04","AP01EDTM":"2022-02-25 07:46:04","AP02SDTM":"2022-02-25 07:46:04","AP02EDTM":"2023-02-25 13:46:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-19","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1040,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.69835,"AVALU":"U/L","BASE2":24.67066,"BASE":21.69911,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-18.97231,"PCHG2":-76.9023,"CHG":-16.00076,"PCHG":-73.73922,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-04-25 19:46:04","ADY":790,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-368","SUBJID":"id-368","SITEID":"BRA-4","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.20454,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-25 19:46:04","TRTEDTM":"2023-02-25 13:46:04","TRT01SDTM":"2020-02-25 19:46:04","TRT01EDTM":"2022-02-25 07:46:04","TRT02SDTM":"2022-02-25 07:46:04","TRT02EDTM":"2023-02-25 13:46:04","AP01SDTM":"2020-02-25 19:46:04","AP01EDTM":"2022-02-25 07:46:04","AP02SDTM":"2022-02-25 07:46:04","AP02EDTM":"2023-02-25 13:46:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-19","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5814,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.09592,"AVALU":"U/L","BASE2":24.67066,"BASE":21.69911,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.57474,"PCHG2":-26.65005,"CHG":-3.60319,"PCHG":-16.60526,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-18 19:46:04","ADY":997,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-368","SUBJID":"id-368","SITEID":"BRA-4","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.20454,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-25 19:46:04","TRTEDTM":"2023-02-25 13:46:04","TRT01SDTM":"2020-02-25 19:46:04","TRT01EDTM":"2022-02-25 07:46:04","TRT02SDTM":"2022-02-25 07:46:04","TRT02EDTM":"2023-02-25 13:46:04","AP01SDTM":"2020-02-25 19:46:04","AP01EDTM":"2022-02-25 07:46:04","AP02SDTM":"2022-02-25 07:46:04","AP02EDTM":"2023-02-25 13:46:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-19","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7811,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.74517,"AVALU":"U/L","BASE2":24.67066,"BASE":21.69911,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.92549,"PCHG2":-72.65913,"CHG":-14.95393,"PCHG":-68.91497,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2023-01-10 19:46:04","ADY":1050,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-368","SUBJID":"id-368","SITEID":"BRA-4","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.20454,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-25 19:46:04","TRTEDTM":"2023-02-25 13:46:04","TRT01SDTM":"2020-02-25 19:46:04","TRT01EDTM":"2022-02-25 07:46:04","TRT02SDTM":"2022-02-25 07:46:04","TRT02EDTM":"2023-02-25 13:46:04","AP01SDTM":"2020-02-25 19:46:04","AP01EDTM":"2022-02-25 07:46:04","AP02SDTM":"2022-02-25 07:46:04","AP02EDTM":"2023-02-25 13:46:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-19","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7850,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.55498,"AVALU":"mg/L","BASE2":7.55498,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-09-23 19:46:04","ADY":211,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-368","SUBJID":"id-368","SITEID":"BRA-4","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.20454,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-25 19:46:04","TRTEDTM":"2023-02-25 13:46:04","TRT01SDTM":"2020-02-25 19:46:04","TRT01EDTM":"2022-02-25 07:46:04","TRT02SDTM":"2022-02-25 07:46:04","TRT02EDTM":"2023-02-25 13:46:04","AP01SDTM":"2020-02-25 19:46:04","AP01EDTM":"2022-02-25 07:46:04","AP02SDTM":"2022-02-25 07:46:04","AP02EDTM":"2023-02-25 13:46:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-19","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7379,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.11032,"AVALU":"mg/L","BASE2":7.55498,"BASE":8.11032,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.55535,"PCHG2":7.35073,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-29 19:46:04","ADY":217,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-368","SUBJID":"id-368","SITEID":"BRA-4","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.20454,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-25 19:46:04","TRTEDTM":"2023-02-25 13:46:04","TRT01SDTM":"2020-02-25 19:46:04","TRT01EDTM":"2022-02-25 07:46:04","TRT02SDTM":"2022-02-25 07:46:04","TRT02EDTM":"2023-02-25 13:46:04","AP01SDTM":"2020-02-25 19:46:04","AP01EDTM":"2022-02-25 07:46:04","AP02SDTM":"2022-02-25 07:46:04","AP02EDTM":"2023-02-25 13:46:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-19","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":528,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.3692,"AVALU":"mg/L","BASE2":7.55498,"BASE":8.11032,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.81422,"PCHG2":10.77732,"CHG":0.25888,"PCHG":3.19196,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-16 19:46:04","ADY":446,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-368","SUBJID":"id-368","SITEID":"BRA-4","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.20454,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-25 19:46:04","TRTEDTM":"2023-02-25 13:46:04","TRT01SDTM":"2020-02-25 19:46:04","TRT01EDTM":"2022-02-25 07:46:04","TRT02SDTM":"2022-02-25 07:46:04","TRT02EDTM":"2023-02-25 13:46:04","AP01SDTM":"2020-02-25 19:46:04","AP01EDTM":"2022-02-25 07:46:04","AP02SDTM":"2022-02-25 07:46:04","AP02EDTM":"2023-02-25 13:46:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-19","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3342,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.25866,"AVALU":"mg/L","BASE2":7.55498,"BASE":8.11032,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.70368,"PCHG2":9.31417,"CHG":0.14834,"PCHG":1.829,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-07 19:46:04","ADY":590,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-368","SUBJID":"id-368","SITEID":"BRA-4","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.20454,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-25 19:46:04","TRTEDTM":"2023-02-25 13:46:04","TRT01SDTM":"2020-02-25 19:46:04","TRT01EDTM":"2022-02-25 07:46:04","TRT02SDTM":"2022-02-25 07:46:04","TRT02EDTM":"2023-02-25 13:46:04","AP01SDTM":"2020-02-25 19:46:04","AP01EDTM":"2022-02-25 07:46:04","AP02SDTM":"2022-02-25 07:46:04","AP02EDTM":"2023-02-25 13:46:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-19","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1708,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.78099,"AVALU":"mg/L","BASE2":7.55498,"BASE":8.11032,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.22601,"PCHG2":29.46419,"CHG":1.67067,"PCHG":20.59926,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-25 19:46:04","ADY":790,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-368","SUBJID":"id-368","SITEID":"BRA-4","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.20454,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-25 19:46:04","TRTEDTM":"2023-02-25 13:46:04","TRT01SDTM":"2020-02-25 19:46:04","TRT01EDTM":"2022-02-25 07:46:04","TRT02SDTM":"2022-02-25 07:46:04","TRT02EDTM":"2023-02-25 13:46:04","AP01SDTM":"2020-02-25 19:46:04","AP01EDTM":"2022-02-25 07:46:04","AP02SDTM":"2022-02-25 07:46:04","AP02EDTM":"2023-02-25 13:46:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-19","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6704,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.73257,"AVALU":"mg/L","BASE2":7.55498,"BASE":8.11032,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17759,"PCHG2":2.35066,"CHG":-0.37775,"PCHG":-4.65769,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2022-11-18 19:46:04","ADY":997,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-368","SUBJID":"id-368","SITEID":"BRA-4","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.20454,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-25 19:46:04","TRTEDTM":"2023-02-25 13:46:04","TRT01SDTM":"2020-02-25 19:46:04","TRT01EDTM":"2022-02-25 07:46:04","TRT02SDTM":"2022-02-25 07:46:04","TRT02EDTM":"2023-02-25 13:46:04","AP01SDTM":"2020-02-25 19:46:04","AP01EDTM":"2022-02-25 07:46:04","AP02SDTM":"2022-02-25 07:46:04","AP02EDTM":"2023-02-25 13:46:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-19","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":457,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.39921,"AVALU":"mg/L","BASE2":7.55498,"BASE":8.11032,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.84424,"PCHG2":37.64717,"CHG":2.28889,"PCHG":28.22193,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2023-01-10 19:46:04","ADY":1050,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-368","SUBJID":"id-368","SITEID":"BRA-4","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.20454,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-25 19:46:04","TRTEDTM":"2023-02-25 13:46:04","TRT01SDTM":"2020-02-25 19:46:04","TRT01EDTM":"2022-02-25 07:46:04","TRT02SDTM":"2022-02-25 07:46:04","TRT02EDTM":"2023-02-25 13:46:04","AP01SDTM":"2020-02-25 19:46:04","AP01EDTM":"2022-02-25 07:46:04","AP02SDTM":"2022-02-25 07:46:04","AP02EDTM":"2023-02-25 13:46:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-19","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7271,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8949,"AVALU":"g/L","BASE2":2.8949,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-23 19:46:04","ADY":211,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-368","SUBJID":"id-368","SITEID":"BRA-4","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.20454,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-25 19:46:04","TRTEDTM":"2023-02-25 13:46:04","TRT01SDTM":"2020-02-25 19:46:04","TRT01EDTM":"2022-02-25 07:46:04","TRT02SDTM":"2022-02-25 07:46:04","TRT02EDTM":"2023-02-25 13:46:04","AP01SDTM":"2020-02-25 19:46:04","AP01EDTM":"2022-02-25 07:46:04","AP02SDTM":"2022-02-25 07:46:04","AP02EDTM":"2023-02-25 13:46:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-19","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2865,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77912,"AVALU":"g/L","BASE2":2.8949,"BASE":2.77912,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.11578,"PCHG2":-3.99939,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-29 19:46:04","ADY":217,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-368","SUBJID":"id-368","SITEID":"BRA-4","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.20454,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-25 19:46:04","TRTEDTM":"2023-02-25 13:46:04","TRT01SDTM":"2020-02-25 19:46:04","TRT01EDTM":"2022-02-25 07:46:04","TRT02SDTM":"2022-02-25 07:46:04","TRT02EDTM":"2023-02-25 13:46:04","AP01SDTM":"2020-02-25 19:46:04","AP01EDTM":"2022-02-25 07:46:04","AP02SDTM":"2022-02-25 07:46:04","AP02EDTM":"2023-02-25 13:46:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-19","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5937,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96866,"AVALU":"g/L","BASE2":2.8949,"BASE":2.77912,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07376,"PCHG2":2.54791,"CHG":0.18954,"PCHG":6.82005,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-16 19:46:04","ADY":446,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-368","SUBJID":"id-368","SITEID":"BRA-4","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.20454,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-25 19:46:04","TRTEDTM":"2023-02-25 13:46:04","TRT01SDTM":"2020-02-25 19:46:04","TRT01EDTM":"2022-02-25 07:46:04","TRT02SDTM":"2022-02-25 07:46:04","TRT02EDTM":"2023-02-25 13:46:04","AP01SDTM":"2020-02-25 19:46:04","AP01EDTM":"2022-02-25 07:46:04","AP02SDTM":"2022-02-25 07:46:04","AP02EDTM":"2023-02-25 13:46:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-19","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4569,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83476,"AVALU":"g/L","BASE2":2.8949,"BASE":2.77912,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06015,"PCHG2":-2.07767,"CHG":0.05563,"PCHG":2.00178,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-07 19:46:04","ADY":590,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-368","SUBJID":"id-368","SITEID":"BRA-4","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.20454,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-25 19:46:04","TRTEDTM":"2023-02-25 13:46:04","TRT01SDTM":"2020-02-25 19:46:04","TRT01EDTM":"2022-02-25 07:46:04","TRT02SDTM":"2022-02-25 07:46:04","TRT02EDTM":"2023-02-25 13:46:04","AP01SDTM":"2020-02-25 19:46:04","AP01EDTM":"2022-02-25 07:46:04","AP02SDTM":"2022-02-25 07:46:04","AP02EDTM":"2023-02-25 13:46:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-19","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5417,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88863,"AVALU":"g/L","BASE2":2.8949,"BASE":2.77912,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00628,"PCHG2":-0.2168,"CHG":0.1095,"PCHG":3.94017,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-25 19:46:04","ADY":790,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-368","SUBJID":"id-368","SITEID":"BRA-4","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.20454,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-25 19:46:04","TRTEDTM":"2023-02-25 13:46:04","TRT01SDTM":"2020-02-25 19:46:04","TRT01EDTM":"2022-02-25 07:46:04","TRT02SDTM":"2022-02-25 07:46:04","TRT02EDTM":"2023-02-25 13:46:04","AP01SDTM":"2020-02-25 19:46:04","AP01EDTM":"2022-02-25 07:46:04","AP02SDTM":"2022-02-25 07:46:04","AP02EDTM":"2023-02-25 13:46:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-19","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3197,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89239,"AVALU":"g/L","BASE2":2.8949,"BASE":2.77912,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00251,"PCHG2":-0.08672,"CHG":0.11327,"PCHG":4.07567,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-18 19:46:04","ADY":997,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-368","SUBJID":"id-368","SITEID":"BRA-4","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.20454,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-25 19:46:04","TRTEDTM":"2023-02-25 13:46:04","TRT01SDTM":"2020-02-25 19:46:04","TRT01EDTM":"2022-02-25 07:46:04","TRT02SDTM":"2022-02-25 07:46:04","TRT02EDTM":"2023-02-25 13:46:04","AP01SDTM":"2020-02-25 19:46:04","AP01EDTM":"2022-02-25 07:46:04","AP02SDTM":"2022-02-25 07:46:04","AP02EDTM":"2023-02-25 13:46:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-19","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6699,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95413,"AVALU":"g/L","BASE2":2.8949,"BASE":2.77912,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05923,"PCHG2":2.046,"CHG":0.17501,"PCHG":6.29724,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-10 19:46:04","ADY":1050,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-383","SUBJID":"id-383","SITEID":"BRA-4","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":4.60353,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-15","TRTSDTM":"2020-01-18 21:44:29","TRT01SDTM":"2020-01-18 21:44:29","AP01SDTM":"2020-01-18 21:44:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1497,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.3275,"AVALU":"U/L","BASE2":3.3275,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-02-26 21:44:29","ADY":39,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-383","SUBJID":"id-383","SITEID":"BRA-4","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":4.60353,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-15","TRTSDTM":"2020-01-18 21:44:29","TRT01SDTM":"2020-01-18 21:44:29","AP01SDTM":"2020-01-18 21:44:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7679,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.5132,"AVALU":"U/L","BASE2":3.3275,"BASE":10.5132,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":7.1857,"PCHG2":215.94906,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-13 21:44:29","ADY":86,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-383","SUBJID":"id-383","SITEID":"BRA-4","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":4.60353,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-15","TRTSDTM":"2020-01-18 21:44:29","TRT01SDTM":"2020-01-18 21:44:29","AP01SDTM":"2020-01-18 21:44:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":915,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.22535,"AVALU":"U/L","BASE2":3.3275,"BASE":10.5132,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.89785,"PCHG2":297.45622,"CHG":2.71215,"PCHG":25.79756,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-22 21:44:29","ADY":186,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-383","SUBJID":"id-383","SITEID":"BRA-4","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":4.60353,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-15","TRTSDTM":"2020-01-18 21:44:29","TRT01SDTM":"2020-01-18 21:44:29","AP01SDTM":"2020-01-18 21:44:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4795,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.92292,"AVALU":"U/L","BASE2":3.3275,"BASE":10.5132,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":29.59542,"PCHG2":889.41904,"CHG":22.40971,"PCHG":213.15777,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-21 21:44:29","ADY":338,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-383","SUBJID":"id-383","SITEID":"BRA-4","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":4.60353,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-15","TRTSDTM":"2020-01-18 21:44:29","TRT01SDTM":"2020-01-18 21:44:29","AP01SDTM":"2020-01-18 21:44:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1123,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.19801,"AVALU":"U/L","BASE2":3.3275,"BASE":10.5132,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.87051,"PCHG2":476.95013,"CHG":8.68481,"PCHG":82.60859,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-17 21:44:29","ADY":365,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-383","SUBJID":"id-383","SITEID":"BRA-4","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":4.60353,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-15","TRTSDTM":"2020-01-18 21:44:29","TRT01SDTM":"2020-01-18 21:44:29","AP01SDTM":"2020-01-18 21:44:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3812,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.89668,"AVALU":"U/L","BASE2":3.3275,"BASE":10.5132,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.56918,"PCHG2":257.52601,"CHG":1.38347,"PCHG":13.15939,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-19 21:44:29","ADY":610,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-383","SUBJID":"id-383","SITEID":"BRA-4","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":4.60353,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-15","TRTSDTM":"2020-01-18 21:44:29","TRT01SDTM":"2020-01-18 21:44:29","AP01SDTM":"2020-01-18 21:44:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7310,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.89903,"AVALU":"U/L","BASE2":3.3275,"BASE":10.5132,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.57153,"PCHG2":257.59676,"CHG":1.38583,"PCHG":13.18178,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-20 21:44:29","ADY":641,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-383","SUBJID":"id-383","SITEID":"BRA-4","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":4.60353,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-15","TRTSDTM":"2020-01-18 21:44:29","TRT01SDTM":"2020-01-18 21:44:29","AP01SDTM":"2020-01-18 21:44:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8232,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.48644,"AVALU":"mg/L","BASE2":8.48644,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-26 21:44:29","ADY":39,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-383","SUBJID":"id-383","SITEID":"BRA-4","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":4.60353,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-15","TRTSDTM":"2020-01-18 21:44:29","TRT01SDTM":"2020-01-18 21:44:29","AP01SDTM":"2020-01-18 21:44:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4283,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.23015,"AVALU":"mg/L","BASE2":8.48644,"BASE":9.23015,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.74371,"PCHG2":8.76352,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-13 21:44:29","ADY":86,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-383","SUBJID":"id-383","SITEID":"BRA-4","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":4.60353,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-15","TRTSDTM":"2020-01-18 21:44:29","TRT01SDTM":"2020-01-18 21:44:29","AP01SDTM":"2020-01-18 21:44:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4296,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.65102,"AVALU":"mg/L","BASE2":8.48644,"BASE":9.23015,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.16458,"PCHG2":13.72284,"CHG":0.42087,"PCHG":4.55972,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-22 21:44:29","ADY":186,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-383","SUBJID":"id-383","SITEID":"BRA-4","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":4.60353,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-15","TRTSDTM":"2020-01-18 21:44:29","TRT01SDTM":"2020-01-18 21:44:29","AP01SDTM":"2020-01-18 21:44:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7871,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.41124,"AVALU":"mg/L","BASE2":8.48644,"BASE":9.23015,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.9248,"PCHG2":10.89733,"CHG":0.18108,"PCHG":1.96188,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-21 21:44:29","ADY":338,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-383","SUBJID":"id-383","SITEID":"BRA-4","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":4.60353,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-15","TRTSDTM":"2020-01-18 21:44:29","TRT01SDTM":"2020-01-18 21:44:29","AP01SDTM":"2020-01-18 21:44:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5379,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.23093,"AVALU":"mg/L","BASE2":8.48644,"BASE":9.23015,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.74449,"PCHG2":8.77271,"CHG":0.00078,"PCHG":0.00845,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-17 21:44:29","ADY":365,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-383","SUBJID":"id-383","SITEID":"BRA-4","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":4.60353,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-15","TRTSDTM":"2020-01-18 21:44:29","TRT01SDTM":"2020-01-18 21:44:29","AP01SDTM":"2020-01-18 21:44:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4348,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.62462,"AVALU":"mg/L","BASE2":8.48644,"BASE":9.23015,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.13818,"PCHG2":13.4117,"CHG":0.39447,"PCHG":4.27366,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-19 21:44:29","ADY":610,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-383","SUBJID":"id-383","SITEID":"BRA-4","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":4.60353,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-15","TRTSDTM":"2020-01-18 21:44:29","TRT01SDTM":"2020-01-18 21:44:29","AP01SDTM":"2020-01-18 21:44:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2088,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.14789,"AVALU":"mg/L","BASE2":8.48644,"BASE":9.23015,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.66145,"PCHG2":19.57774,"CHG":0.91774,"PCHG":9.94288,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-10-20 21:44:29","ADY":641,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-383","SUBJID":"id-383","SITEID":"BRA-4","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":4.60353,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-15","TRTSDTM":"2020-01-18 21:44:29","TRT01SDTM":"2020-01-18 21:44:29","AP01SDTM":"2020-01-18 21:44:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6712,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76586,"AVALU":"g/L","BASE2":2.76586,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-02-26 21:44:29","ADY":39,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-383","SUBJID":"id-383","SITEID":"BRA-4","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":4.60353,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-15","TRTSDTM":"2020-01-18 21:44:29","TRT01SDTM":"2020-01-18 21:44:29","AP01SDTM":"2020-01-18 21:44:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8234,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04487,"AVALU":"g/L","BASE2":2.76586,"BASE":3.04487,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.27901,"PCHG2":10.08763,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2020-04-13 21:44:29","ADY":86,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-383","SUBJID":"id-383","SITEID":"BRA-4","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":4.60353,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-15","TRTSDTM":"2020-01-18 21:44:29","TRT01SDTM":"2020-01-18 21:44:29","AP01SDTM":"2020-01-18 21:44:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6128,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78285,"AVALU":"g/L","BASE2":2.76586,"BASE":3.04487,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01698,"PCHG2":0.61406,"CHG":-0.26203,"PCHG":-8.60548,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-07-22 21:44:29","ADY":186,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-383","SUBJID":"id-383","SITEID":"BRA-4","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":4.60353,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-15","TRTSDTM":"2020-01-18 21:44:29","TRT01SDTM":"2020-01-18 21:44:29","AP01SDTM":"2020-01-18 21:44:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7711,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9128,"AVALU":"g/L","BASE2":2.76586,"BASE":3.04487,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14693,"PCHG2":5.31235,"CHG":-0.13208,"PCHG":-4.33771,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-12-21 21:44:29","ADY":338,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-383","SUBJID":"id-383","SITEID":"BRA-4","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":4.60353,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-15","TRTSDTM":"2020-01-18 21:44:29","TRT01SDTM":"2020-01-18 21:44:29","AP01SDTM":"2020-01-18 21:44:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":818,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8896,"AVALU":"g/L","BASE2":2.76586,"BASE":3.04487,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12374,"PCHG2":4.47374,"CHG":-0.15527,"PCHG":-5.09948,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-01-17 21:44:29","ADY":365,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-383","SUBJID":"id-383","SITEID":"BRA-4","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":4.60353,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-15","TRTSDTM":"2020-01-18 21:44:29","TRT01SDTM":"2020-01-18 21:44:29","AP01SDTM":"2020-01-18 21:44:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":666,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89815,"AVALU":"g/L","BASE2":2.76586,"BASE":3.04487,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13229,"PCHG2":4.78292,"CHG":-0.14672,"PCHG":-4.81863,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-09-19 21:44:29","ADY":610,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-4-id-383","SUBJID":"id-383","SITEID":"BRA-4","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-4","INVNAM":"Dr. BRA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":4.60353,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-15","TRTSDTM":"2020-01-18 21:44:29","TRT01SDTM":"2020-01-18 21:44:29","AP01SDTM":"2020-01-18 21:44:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4943,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77823,"AVALU":"g/L","BASE2":2.76586,"BASE":3.04487,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01236,"PCHG2":0.44703,"CHG":-0.26665,"PCHG":-8.7572,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-10-20 21:44:29","ADY":641,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-5-id-234","SUBJID":"id-234","SITEID":"BRA-5","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-5","INVNAM":"Dr. BRA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.86786,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-21","TRTSDTM":"2019-06-22 20:47:28","TRTEDTM":"2022-06-22 14:47:28","TRT01SDTM":"2019-06-22 20:47:28","TRT01EDTM":"2021-06-22 08:47:28","TRT02SDTM":"2021-06-22 08:47:28","TRT02EDTM":"2022-06-22 14:47:28","AP01SDTM":"2019-06-22 20:47:28","AP01EDTM":"2021-06-22 08:47:28","AP02SDTM":"2021-06-22 08:47:28","AP02EDTM":"2022-06-22 14:47:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-22","EOSDY":1096,"LSTALVDT":"2022-07-06","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3377,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.55865,"AVALU":"U/L","BASE2":7.55865,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-06-23 20:47:28","ADY":1,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-5-id-234","SUBJID":"id-234","SITEID":"BRA-5","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-5","INVNAM":"Dr. BRA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.86786,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-21","TRTSDTM":"2019-06-22 20:47:28","TRTEDTM":"2022-06-22 14:47:28","TRT01SDTM":"2019-06-22 20:47:28","TRT01EDTM":"2021-06-22 08:47:28","TRT02SDTM":"2021-06-22 08:47:28","TRT02EDTM":"2022-06-22 14:47:28","AP01SDTM":"2019-06-22 20:47:28","AP01EDTM":"2021-06-22 08:47:28","AP02SDTM":"2021-06-22 08:47:28","AP02EDTM":"2022-06-22 14:47:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-22","EOSDY":1096,"LSTALVDT":"2022-07-06","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2772,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.89959,"AVALU":"U/L","BASE2":7.55865,"BASE":17.89959,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":10.34093,"PCHG2":136.80918,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-08 20:47:28","ADY":16,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-5-id-234","SUBJID":"id-234","SITEID":"BRA-5","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-5","INVNAM":"Dr. BRA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.86786,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-21","TRTSDTM":"2019-06-22 20:47:28","TRTEDTM":"2022-06-22 14:47:28","TRT01SDTM":"2019-06-22 20:47:28","TRT01EDTM":"2021-06-22 08:47:28","TRT02SDTM":"2021-06-22 08:47:28","TRT02EDTM":"2022-06-22 14:47:28","AP01SDTM":"2019-06-22 20:47:28","AP01EDTM":"2021-06-22 08:47:28","AP02SDTM":"2021-06-22 08:47:28","AP02EDTM":"2022-06-22 14:47:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-22","EOSDY":1096,"LSTALVDT":"2022-07-06","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7333,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.02612,"AVALU":"U/L","BASE2":7.55865,"BASE":17.89959,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.53254,"PCHG2":-33.50511,"CHG":-12.87347,"PCHG":-71.92048,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2019-11-01 20:47:28","ADY":132,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-5-id-234","SUBJID":"id-234","SITEID":"BRA-5","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-5","INVNAM":"Dr. BRA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.86786,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-21","TRTSDTM":"2019-06-22 20:47:28","TRTEDTM":"2022-06-22 14:47:28","TRT01SDTM":"2019-06-22 20:47:28","TRT01EDTM":"2021-06-22 08:47:28","TRT02SDTM":"2021-06-22 08:47:28","TRT02EDTM":"2022-06-22 14:47:28","AP01SDTM":"2019-06-22 20:47:28","AP01EDTM":"2021-06-22 08:47:28","AP02SDTM":"2021-06-22 08:47:28","AP02EDTM":"2022-06-22 14:47:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-22","EOSDY":1096,"LSTALVDT":"2022-07-06","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2360,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.16416,"AVALU":"U/L","BASE2":7.55865,"BASE":17.89959,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":21.60551,"PCHG2":285.83804,"CHG":11.26458,"PCHG":62.93204,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-10 20:47:28","ADY":202,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-5-id-234","SUBJID":"id-234","SITEID":"BRA-5","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-5","INVNAM":"Dr. BRA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.86786,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-21","TRTSDTM":"2019-06-22 20:47:28","TRTEDTM":"2022-06-22 14:47:28","TRT01SDTM":"2019-06-22 20:47:28","TRT01EDTM":"2021-06-22 08:47:28","TRT02SDTM":"2021-06-22 08:47:28","TRT02EDTM":"2022-06-22 14:47:28","AP01SDTM":"2019-06-22 20:47:28","AP01EDTM":"2021-06-22 08:47:28","AP02SDTM":"2021-06-22 08:47:28","AP02EDTM":"2022-06-22 14:47:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-22","EOSDY":1096,"LSTALVDT":"2022-07-06","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5316,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.0802,"AVALU":"U/L","BASE2":7.55865,"BASE":17.89959,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":25.52155,"PCHG2":337.6467,"CHG":15.18061,"PCHG":84.80986,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-08 20:47:28","ADY":444,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-5-id-234","SUBJID":"id-234","SITEID":"BRA-5","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-5","INVNAM":"Dr. BRA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.86786,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-21","TRTSDTM":"2019-06-22 20:47:28","TRTEDTM":"2022-06-22 14:47:28","TRT01SDTM":"2019-06-22 20:47:28","TRT01EDTM":"2021-06-22 08:47:28","TRT02SDTM":"2021-06-22 08:47:28","TRT02EDTM":"2022-06-22 14:47:28","AP01SDTM":"2019-06-22 20:47:28","AP01EDTM":"2021-06-22 08:47:28","AP02SDTM":"2021-06-22 08:47:28","AP02EDTM":"2022-06-22 14:47:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-22","EOSDY":1096,"LSTALVDT":"2022-07-06","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5270,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.30086,"AVALU":"U/L","BASE2":7.55865,"BASE":17.89959,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":22.7422,"PCHG2":300.87638,"CHG":12.40127,"PCHG":69.28245,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-18 20:47:28","ADY":607,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-5-id-234","SUBJID":"id-234","SITEID":"BRA-5","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-5","INVNAM":"Dr. BRA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.86786,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-21","TRTSDTM":"2019-06-22 20:47:28","TRTEDTM":"2022-06-22 14:47:28","TRT01SDTM":"2019-06-22 20:47:28","TRT01EDTM":"2021-06-22 08:47:28","TRT02SDTM":"2021-06-22 08:47:28","TRT02EDTM":"2022-06-22 14:47:28","AP01SDTM":"2019-06-22 20:47:28","AP01EDTM":"2021-06-22 08:47:28","AP02SDTM":"2021-06-22 08:47:28","AP02EDTM":"2022-06-22 14:47:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-22","EOSDY":1096,"LSTALVDT":"2022-07-06","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7972,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.99604,"AVALU":"U/L","BASE2":7.55865,"BASE":17.89959,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.56261,"PCHG2":-60.36272,"CHG":-14.90354,"PCHG":-83.26193,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-03-15 20:47:28","ADY":632,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-5-id-234","SUBJID":"id-234","SITEID":"BRA-5","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-5","INVNAM":"Dr. BRA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.86786,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-21","TRTSDTM":"2019-06-22 20:47:28","TRTEDTM":"2022-06-22 14:47:28","TRT01SDTM":"2019-06-22 20:47:28","TRT01EDTM":"2021-06-22 08:47:28","TRT02SDTM":"2021-06-22 08:47:28","TRT02EDTM":"2022-06-22 14:47:28","AP01SDTM":"2019-06-22 20:47:28","AP01EDTM":"2021-06-22 08:47:28","AP02SDTM":"2021-06-22 08:47:28","AP02EDTM":"2022-06-22 14:47:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-22","EOSDY":1096,"LSTALVDT":"2022-07-06","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3868,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.67052,"AVALU":"mg/L","BASE2":7.67052,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2019-06-23 20:47:28","ADY":1,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-5-id-234","SUBJID":"id-234","SITEID":"BRA-5","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-5","INVNAM":"Dr. BRA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.86786,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-21","TRTSDTM":"2019-06-22 20:47:28","TRTEDTM":"2022-06-22 14:47:28","TRT01SDTM":"2019-06-22 20:47:28","TRT01EDTM":"2021-06-22 08:47:28","TRT02SDTM":"2021-06-22 08:47:28","TRT02EDTM":"2022-06-22 14:47:28","AP01SDTM":"2019-06-22 20:47:28","AP01EDTM":"2021-06-22 08:47:28","AP02SDTM":"2021-06-22 08:47:28","AP02EDTM":"2022-06-22 14:47:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-22","EOSDY":1096,"LSTALVDT":"2022-07-06","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8048,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.79937,"AVALU":"mg/L","BASE2":7.67052,"BASE":8.79937,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.12885,"PCHG2":14.71672,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-08 20:47:28","ADY":16,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-5-id-234","SUBJID":"id-234","SITEID":"BRA-5","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-5","INVNAM":"Dr. BRA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.86786,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-21","TRTSDTM":"2019-06-22 20:47:28","TRTEDTM":"2022-06-22 14:47:28","TRT01SDTM":"2019-06-22 20:47:28","TRT01EDTM":"2021-06-22 08:47:28","TRT02SDTM":"2021-06-22 08:47:28","TRT02EDTM":"2022-06-22 14:47:28","AP01SDTM":"2019-06-22 20:47:28","AP01EDTM":"2021-06-22 08:47:28","AP02SDTM":"2021-06-22 08:47:28","AP02EDTM":"2022-06-22 14:47:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-22","EOSDY":1096,"LSTALVDT":"2022-07-06","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5840,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.40889,"AVALU":"mg/L","BASE2":7.67052,"BASE":8.79937,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.73836,"PCHG2":9.62594,"CHG":-0.39049,"PCHG":-4.43769,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-01 20:47:28","ADY":132,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-5-id-234","SUBJID":"id-234","SITEID":"BRA-5","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-5","INVNAM":"Dr. BRA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.86786,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-21","TRTSDTM":"2019-06-22 20:47:28","TRTEDTM":"2022-06-22 14:47:28","TRT01SDTM":"2019-06-22 20:47:28","TRT01EDTM":"2021-06-22 08:47:28","TRT02SDTM":"2021-06-22 08:47:28","TRT02EDTM":"2022-06-22 14:47:28","AP01SDTM":"2019-06-22 20:47:28","AP01EDTM":"2021-06-22 08:47:28","AP02SDTM":"2021-06-22 08:47:28","AP02EDTM":"2022-06-22 14:47:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-22","EOSDY":1096,"LSTALVDT":"2022-07-06","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8356,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.8204,"AVALU":"mg/L","BASE2":7.67052,"BASE":8.79937,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.14987,"PCHG2":14.99077,"CHG":0.02102,"PCHG":0.23889,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-10 20:47:28","ADY":202,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-5-id-234","SUBJID":"id-234","SITEID":"BRA-5","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-5","INVNAM":"Dr. BRA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.86786,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-21","TRTSDTM":"2019-06-22 20:47:28","TRTEDTM":"2022-06-22 14:47:28","TRT01SDTM":"2019-06-22 20:47:28","TRT01EDTM":"2021-06-22 08:47:28","TRT02SDTM":"2021-06-22 08:47:28","TRT02EDTM":"2022-06-22 14:47:28","AP01SDTM":"2019-06-22 20:47:28","AP01EDTM":"2021-06-22 08:47:28","AP02SDTM":"2021-06-22 08:47:28","AP02EDTM":"2022-06-22 14:47:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-22","EOSDY":1096,"LSTALVDT":"2022-07-06","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6303,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.92812,"AVALU":"mg/L","BASE2":7.67052,"BASE":8.79937,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.74241,"PCHG2":-9.67871,"CHG":-1.87126,"PCHG":-21.2658,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-09-08 20:47:28","ADY":444,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-5-id-234","SUBJID":"id-234","SITEID":"BRA-5","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-5","INVNAM":"Dr. BRA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.86786,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-21","TRTSDTM":"2019-06-22 20:47:28","TRTEDTM":"2022-06-22 14:47:28","TRT01SDTM":"2019-06-22 20:47:28","TRT01EDTM":"2021-06-22 08:47:28","TRT02SDTM":"2021-06-22 08:47:28","TRT02EDTM":"2022-06-22 14:47:28","AP01SDTM":"2019-06-22 20:47:28","AP01EDTM":"2021-06-22 08:47:28","AP02SDTM":"2021-06-22 08:47:28","AP02EDTM":"2022-06-22 14:47:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-22","EOSDY":1096,"LSTALVDT":"2022-07-06","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5812,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.21242,"AVALU":"mg/L","BASE2":7.67052,"BASE":8.79937,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.54189,"PCHG2":7.06464,"CHG":-0.58695,"PCHG":-6.67041,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-18 20:47:28","ADY":607,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-5-id-234","SUBJID":"id-234","SITEID":"BRA-5","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-5","INVNAM":"Dr. BRA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.86786,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-21","TRTSDTM":"2019-06-22 20:47:28","TRTEDTM":"2022-06-22 14:47:28","TRT01SDTM":"2019-06-22 20:47:28","TRT01EDTM":"2021-06-22 08:47:28","TRT02SDTM":"2021-06-22 08:47:28","TRT02EDTM":"2022-06-22 14:47:28","AP01SDTM":"2019-06-22 20:47:28","AP01EDTM":"2021-06-22 08:47:28","AP02SDTM":"2021-06-22 08:47:28","AP02EDTM":"2022-06-22 14:47:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-22","EOSDY":1096,"LSTALVDT":"2022-07-06","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5333,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.66531,"AVALU":"mg/L","BASE2":7.67052,"BASE":8.79937,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.99478,"PCHG2":39.04276,"CHG":1.86594,"PCHG":21.20532,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-03-15 20:47:28","ADY":632,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-5-id-234","SUBJID":"id-234","SITEID":"BRA-5","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-5","INVNAM":"Dr. BRA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.86786,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-21","TRTSDTM":"2019-06-22 20:47:28","TRTEDTM":"2022-06-22 14:47:28","TRT01SDTM":"2019-06-22 20:47:28","TRT01EDTM":"2021-06-22 08:47:28","TRT02SDTM":"2021-06-22 08:47:28","TRT02EDTM":"2022-06-22 14:47:28","AP01SDTM":"2019-06-22 20:47:28","AP01EDTM":"2021-06-22 08:47:28","AP02SDTM":"2021-06-22 08:47:28","AP02EDTM":"2022-06-22 14:47:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-22","EOSDY":1096,"LSTALVDT":"2022-07-06","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2230,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.784,"AVALU":"g/L","BASE2":2.784,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-06-23 20:47:28","ADY":1,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-5-id-234","SUBJID":"id-234","SITEID":"BRA-5","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-5","INVNAM":"Dr. BRA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.86786,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-21","TRTSDTM":"2019-06-22 20:47:28","TRTEDTM":"2022-06-22 14:47:28","TRT01SDTM":"2019-06-22 20:47:28","TRT01EDTM":"2021-06-22 08:47:28","TRT02SDTM":"2021-06-22 08:47:28","TRT02EDTM":"2022-06-22 14:47:28","AP01SDTM":"2019-06-22 20:47:28","AP01EDTM":"2021-06-22 08:47:28","AP02SDTM":"2021-06-22 08:47:28","AP02EDTM":"2022-06-22 14:47:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-22","EOSDY":1096,"LSTALVDT":"2022-07-06","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4092,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88939,"AVALU":"g/L","BASE2":2.784,"BASE":2.88939,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.1054,"PCHG2":3.7858,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-08 20:47:28","ADY":16,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-5-id-234","SUBJID":"id-234","SITEID":"BRA-5","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-5","INVNAM":"Dr. BRA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.86786,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-21","TRTSDTM":"2019-06-22 20:47:28","TRTEDTM":"2022-06-22 14:47:28","TRT01SDTM":"2019-06-22 20:47:28","TRT01EDTM":"2021-06-22 08:47:28","TRT02SDTM":"2021-06-22 08:47:28","TRT02EDTM":"2022-06-22 14:47:28","AP01SDTM":"2019-06-22 20:47:28","AP01EDTM":"2021-06-22 08:47:28","AP02SDTM":"2021-06-22 08:47:28","AP02EDTM":"2022-06-22 14:47:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-22","EOSDY":1096,"LSTALVDT":"2022-07-06","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4019,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83399,"AVALU":"g/L","BASE2":2.784,"BASE":2.88939,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04999,"PCHG2":1.79552,"CHG":-0.05541,"PCHG":-1.91768,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-01 20:47:28","ADY":132,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-5-id-234","SUBJID":"id-234","SITEID":"BRA-5","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-5","INVNAM":"Dr. BRA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.86786,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-21","TRTSDTM":"2019-06-22 20:47:28","TRTEDTM":"2022-06-22 14:47:28","TRT01SDTM":"2019-06-22 20:47:28","TRT01EDTM":"2021-06-22 08:47:28","TRT02SDTM":"2021-06-22 08:47:28","TRT02EDTM":"2022-06-22 14:47:28","AP01SDTM":"2019-06-22 20:47:28","AP01EDTM":"2021-06-22 08:47:28","AP02SDTM":"2021-06-22 08:47:28","AP02EDTM":"2022-06-22 14:47:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-22","EOSDY":1096,"LSTALVDT":"2022-07-06","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1564,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87346,"AVALU":"g/L","BASE2":2.784,"BASE":2.88939,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08946,"PCHG2":3.2135,"CHG":-0.01593,"PCHG":-0.55143,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-10 20:47:28","ADY":202,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-5-id-234","SUBJID":"id-234","SITEID":"BRA-5","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-5","INVNAM":"Dr. BRA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.86786,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-21","TRTSDTM":"2019-06-22 20:47:28","TRTEDTM":"2022-06-22 14:47:28","TRT01SDTM":"2019-06-22 20:47:28","TRT01EDTM":"2021-06-22 08:47:28","TRT02SDTM":"2021-06-22 08:47:28","TRT02EDTM":"2022-06-22 14:47:28","AP01SDTM":"2019-06-22 20:47:28","AP01EDTM":"2021-06-22 08:47:28","AP02SDTM":"2021-06-22 08:47:28","AP02EDTM":"2022-06-22 14:47:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-22","EOSDY":1096,"LSTALVDT":"2022-07-06","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6788,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88592,"AVALU":"g/L","BASE2":2.784,"BASE":2.88939,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10192,"PCHG2":3.66086,"CHG":-0.00348,"PCHG":-0.12038,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-08 20:47:28","ADY":444,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-5-id-234","SUBJID":"id-234","SITEID":"BRA-5","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-5","INVNAM":"Dr. BRA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.86786,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-21","TRTSDTM":"2019-06-22 20:47:28","TRTEDTM":"2022-06-22 14:47:28","TRT01SDTM":"2019-06-22 20:47:28","TRT01EDTM":"2021-06-22 08:47:28","TRT02SDTM":"2021-06-22 08:47:28","TRT02EDTM":"2022-06-22 14:47:28","AP01SDTM":"2019-06-22 20:47:28","AP01EDTM":"2021-06-22 08:47:28","AP02SDTM":"2021-06-22 08:47:28","AP02EDTM":"2022-06-22 14:47:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-22","EOSDY":1096,"LSTALVDT":"2022-07-06","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3268,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87571,"AVALU":"g/L","BASE2":2.784,"BASE":2.88939,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09171,"PCHG2":3.29426,"CHG":-0.01368,"PCHG":-0.47361,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-18 20:47:28","ADY":607,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-5-id-234","SUBJID":"id-234","SITEID":"BRA-5","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-5","INVNAM":"Dr. BRA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.86786,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-21","TRTSDTM":"2019-06-22 20:47:28","TRTEDTM":"2022-06-22 14:47:28","TRT01SDTM":"2019-06-22 20:47:28","TRT01EDTM":"2021-06-22 08:47:28","TRT02SDTM":"2021-06-22 08:47:28","TRT02EDTM":"2022-06-22 14:47:28","AP01SDTM":"2019-06-22 20:47:28","AP01EDTM":"2021-06-22 08:47:28","AP02SDTM":"2021-06-22 08:47:28","AP02EDTM":"2022-06-22 14:47:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-22","EOSDY":1096,"LSTALVDT":"2022-07-06","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6235,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02679,"AVALU":"g/L","BASE2":2.784,"BASE":2.88939,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.24279,"PCHG2":8.72084,"CHG":0.13739,"PCHG":4.75503,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-03-15 20:47:28","ADY":632,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-6-id-369","SUBJID":"id-369","SITEID":"BRA-6","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-6","INVNAM":"Dr. BRA-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":5.41359,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-09","TRTSDTM":"2020-08-13 10:27:02","TRTEDTM":"2023-08-14 04:27:02","TRT01SDTM":"2020-08-13 10:27:02","TRT01EDTM":"2022-08-13 22:27:02","TRT02SDTM":"2022-08-13 22:27:02","TRT02EDTM":"2023-08-14 04:27:02","AP01SDTM":"2020-08-13 10:27:02","AP01EDTM":"2022-08-13 22:27:02","AP02SDTM":"2022-08-13 22:27:02","AP02EDTM":"2023-08-14 04:27:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-14","EOSDY":1096,"LSTALVDT":"2023-08-27","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2010,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.65599,"AVALU":"U/L","BASE2":25.65599,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-25 10:27:02","ADY":134,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-6-id-369","SUBJID":"id-369","SITEID":"BRA-6","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-6","INVNAM":"Dr. BRA-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":5.41359,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-09","TRTSDTM":"2020-08-13 10:27:02","TRTEDTM":"2023-08-14 04:27:02","TRT01SDTM":"2020-08-13 10:27:02","TRT01EDTM":"2022-08-13 22:27:02","TRT02SDTM":"2022-08-13 22:27:02","TRT02EDTM":"2023-08-14 04:27:02","AP01SDTM":"2020-08-13 10:27:02","AP01EDTM":"2022-08-13 22:27:02","AP02SDTM":"2022-08-13 22:27:02","AP02EDTM":"2023-08-14 04:27:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-14","EOSDY":1096,"LSTALVDT":"2023-08-27","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5250,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.07735,"AVALU":"U/L","BASE2":25.65599,"BASE":14.07735,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-11.57864,"PCHG2":-45.13034,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-02 10:27:02","ADY":566,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-6-id-369","SUBJID":"id-369","SITEID":"BRA-6","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-6","INVNAM":"Dr. BRA-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":5.41359,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-09","TRTSDTM":"2020-08-13 10:27:02","TRTEDTM":"2023-08-14 04:27:02","TRT01SDTM":"2020-08-13 10:27:02","TRT01EDTM":"2022-08-13 22:27:02","TRT02SDTM":"2022-08-13 22:27:02","TRT02EDTM":"2023-08-14 04:27:02","AP01SDTM":"2020-08-13 10:27:02","AP01EDTM":"2022-08-13 22:27:02","AP02SDTM":"2022-08-13 22:27:02","AP02EDTM":"2023-08-14 04:27:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-14","EOSDY":1096,"LSTALVDT":"2023-08-27","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":870,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.95747,"AVALU":"U/L","BASE2":25.65599,"BASE":14.07735,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.69852,"PCHG2":-68.98398,"CHG":-6.11989,"PCHG":-43.47328,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-06 10:27:02","ADY":570,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-6-id-369","SUBJID":"id-369","SITEID":"BRA-6","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-6","INVNAM":"Dr. BRA-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":5.41359,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-09","TRTSDTM":"2020-08-13 10:27:02","TRTEDTM":"2023-08-14 04:27:02","TRT01SDTM":"2020-08-13 10:27:02","TRT01EDTM":"2022-08-13 22:27:02","TRT02SDTM":"2022-08-13 22:27:02","TRT02EDTM":"2023-08-14 04:27:02","AP01SDTM":"2020-08-13 10:27:02","AP01EDTM":"2022-08-13 22:27:02","AP02SDTM":"2022-08-13 22:27:02","AP02EDTM":"2023-08-14 04:27:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-14","EOSDY":1096,"LSTALVDT":"2023-08-27","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2095,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.10626,"AVALU":"U/L","BASE2":25.65599,"BASE":14.07735,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.54973,"PCHG2":-45.01769,"CHG":0.0289,"PCHG":0.20532,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-29 10:27:02","ADY":593,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-6-id-369","SUBJID":"id-369","SITEID":"BRA-6","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-6","INVNAM":"Dr. BRA-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":5.41359,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-09","TRTSDTM":"2020-08-13 10:27:02","TRTEDTM":"2023-08-14 04:27:02","TRT01SDTM":"2020-08-13 10:27:02","TRT01EDTM":"2022-08-13 22:27:02","TRT02SDTM":"2022-08-13 22:27:02","TRT02EDTM":"2023-08-14 04:27:02","AP01SDTM":"2020-08-13 10:27:02","AP01EDTM":"2022-08-13 22:27:02","AP02SDTM":"2022-08-13 22:27:02","AP02EDTM":"2023-08-14 04:27:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-14","EOSDY":1096,"LSTALVDT":"2023-08-27","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1833,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.24752,"AVALU":"U/L","BASE2":25.65599,"BASE":14.07735,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.40847,"PCHG2":-21.08073,"CHG":6.17017,"PCHG":43.83045,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-19 10:27:02","ADY":736,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-6-id-369","SUBJID":"id-369","SITEID":"BRA-6","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-6","INVNAM":"Dr. BRA-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":5.41359,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-09","TRTSDTM":"2020-08-13 10:27:02","TRTEDTM":"2023-08-14 04:27:02","TRT01SDTM":"2020-08-13 10:27:02","TRT01EDTM":"2022-08-13 22:27:02","TRT02SDTM":"2022-08-13 22:27:02","TRT02EDTM":"2023-08-14 04:27:02","AP01SDTM":"2020-08-13 10:27:02","AP01EDTM":"2022-08-13 22:27:02","AP02SDTM":"2022-08-13 22:27:02","AP02EDTM":"2023-08-14 04:27:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-14","EOSDY":1096,"LSTALVDT":"2023-08-27","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3639,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.65268,"AVALU":"U/L","BASE2":25.65599,"BASE":14.07735,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.00331,"PCHG2":-50.68335,"CHG":-1.42468,"PCHG":-10.12036,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-03 10:27:02","ADY":812,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-6-id-369","SUBJID":"id-369","SITEID":"BRA-6","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-6","INVNAM":"Dr. BRA-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":5.41359,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-09","TRTSDTM":"2020-08-13 10:27:02","TRTEDTM":"2023-08-14 04:27:02","TRT01SDTM":"2020-08-13 10:27:02","TRT01EDTM":"2022-08-13 22:27:02","TRT02SDTM":"2022-08-13 22:27:02","TRT02EDTM":"2023-08-14 04:27:02","AP01SDTM":"2020-08-13 10:27:02","AP01EDTM":"2022-08-13 22:27:02","AP02SDTM":"2022-08-13 22:27:02","AP02EDTM":"2023-08-14 04:27:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-14","EOSDY":1096,"LSTALVDT":"2023-08-27","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2577,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.49667,"AVALU":"U/L","BASE2":25.65599,"BASE":14.07735,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15932,"PCHG2":-0.621,"CHG":11.41931,"PCHG":81.11833,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-21 10:27:02","ADY":922,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-6-id-369","SUBJID":"id-369","SITEID":"BRA-6","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-6","INVNAM":"Dr. BRA-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":5.41359,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-09","TRTSDTM":"2020-08-13 10:27:02","TRTEDTM":"2023-08-14 04:27:02","TRT01SDTM":"2020-08-13 10:27:02","TRT01EDTM":"2022-08-13 22:27:02","TRT02SDTM":"2022-08-13 22:27:02","TRT02EDTM":"2023-08-14 04:27:02","AP01SDTM":"2020-08-13 10:27:02","AP01EDTM":"2022-08-13 22:27:02","AP02SDTM":"2022-08-13 22:27:02","AP02EDTM":"2023-08-14 04:27:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-14","EOSDY":1096,"LSTALVDT":"2023-08-27","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4454,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.86615,"AVALU":"mg/L","BASE2":7.86615,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-12-25 10:27:02","ADY":134,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-6-id-369","SUBJID":"id-369","SITEID":"BRA-6","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-6","INVNAM":"Dr. BRA-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":5.41359,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-09","TRTSDTM":"2020-08-13 10:27:02","TRTEDTM":"2023-08-14 04:27:02","TRT01SDTM":"2020-08-13 10:27:02","TRT01EDTM":"2022-08-13 22:27:02","TRT02SDTM":"2022-08-13 22:27:02","TRT02EDTM":"2023-08-14 04:27:02","AP01SDTM":"2020-08-13 10:27:02","AP01EDTM":"2022-08-13 22:27:02","AP02SDTM":"2022-08-13 22:27:02","AP02EDTM":"2023-08-14 04:27:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-14","EOSDY":1096,"LSTALVDT":"2023-08-27","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6285,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.19377,"AVALU":"mg/L","BASE2":7.86615,"BASE":9.19377,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.32761,"PCHG2":16.87756,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-02 10:27:02","ADY":566,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-6-id-369","SUBJID":"id-369","SITEID":"BRA-6","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-6","INVNAM":"Dr. BRA-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":5.41359,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-09","TRTSDTM":"2020-08-13 10:27:02","TRTEDTM":"2023-08-14 04:27:02","TRT01SDTM":"2020-08-13 10:27:02","TRT01EDTM":"2022-08-13 22:27:02","TRT02SDTM":"2022-08-13 22:27:02","TRT02EDTM":"2023-08-14 04:27:02","AP01SDTM":"2020-08-13 10:27:02","AP01EDTM":"2022-08-13 22:27:02","AP02SDTM":"2022-08-13 22:27:02","AP02EDTM":"2023-08-14 04:27:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-14","EOSDY":1096,"LSTALVDT":"2023-08-27","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2392,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.43497,"AVALU":"mg/L","BASE2":7.86615,"BASE":9.19377,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.56882,"PCHG2":19.94393,"CHG":0.24121,"PCHG":2.62357,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-06 10:27:02","ADY":570,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-6-id-369","SUBJID":"id-369","SITEID":"BRA-6","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-6","INVNAM":"Dr. BRA-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":5.41359,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-09","TRTSDTM":"2020-08-13 10:27:02","TRTEDTM":"2023-08-14 04:27:02","TRT01SDTM":"2020-08-13 10:27:02","TRT01EDTM":"2022-08-13 22:27:02","TRT02SDTM":"2022-08-13 22:27:02","TRT02EDTM":"2023-08-14 04:27:02","AP01SDTM":"2020-08-13 10:27:02","AP01EDTM":"2022-08-13 22:27:02","AP02SDTM":"2022-08-13 22:27:02","AP02EDTM":"2023-08-14 04:27:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-14","EOSDY":1096,"LSTALVDT":"2023-08-27","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2269,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.58848,"AVALU":"mg/L","BASE2":7.86615,"BASE":9.19377,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.72233,"PCHG2":9.18276,"CHG":-0.60529,"PCHG":-6.58365,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-29 10:27:02","ADY":593,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-6-id-369","SUBJID":"id-369","SITEID":"BRA-6","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-6","INVNAM":"Dr. BRA-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":5.41359,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-09","TRTSDTM":"2020-08-13 10:27:02","TRTEDTM":"2023-08-14 04:27:02","TRT01SDTM":"2020-08-13 10:27:02","TRT01EDTM":"2022-08-13 22:27:02","TRT02SDTM":"2022-08-13 22:27:02","TRT02EDTM":"2023-08-14 04:27:02","AP01SDTM":"2020-08-13 10:27:02","AP01EDTM":"2022-08-13 22:27:02","AP02SDTM":"2022-08-13 22:27:02","AP02EDTM":"2023-08-14 04:27:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-14","EOSDY":1096,"LSTALVDT":"2023-08-27","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3689,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.75715,"AVALU":"mg/L","BASE2":7.86615,"BASE":9.19377,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.891,"PCHG2":24.03971,"CHG":0.56339,"PCHG":6.12791,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-19 10:27:02","ADY":736,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-6-id-369","SUBJID":"id-369","SITEID":"BRA-6","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-6","INVNAM":"Dr. BRA-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":5.41359,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-09","TRTSDTM":"2020-08-13 10:27:02","TRTEDTM":"2023-08-14 04:27:02","TRT01SDTM":"2020-08-13 10:27:02","TRT01EDTM":"2022-08-13 22:27:02","TRT02SDTM":"2022-08-13 22:27:02","TRT02EDTM":"2023-08-14 04:27:02","AP01SDTM":"2020-08-13 10:27:02","AP01EDTM":"2022-08-13 22:27:02","AP02SDTM":"2022-08-13 22:27:02","AP02EDTM":"2023-08-14 04:27:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-14","EOSDY":1096,"LSTALVDT":"2023-08-27","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":763,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.83334,"AVALU":"mg/L","BASE2":7.86615,"BASE":9.19377,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.96719,"PCHG2":25.00825,"CHG":0.63957,"PCHG":6.95658,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-03 10:27:02","ADY":812,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-6-id-369","SUBJID":"id-369","SITEID":"BRA-6","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-6","INVNAM":"Dr. BRA-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":5.41359,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-09","TRTSDTM":"2020-08-13 10:27:02","TRTEDTM":"2023-08-14 04:27:02","TRT01SDTM":"2020-08-13 10:27:02","TRT01EDTM":"2022-08-13 22:27:02","TRT02SDTM":"2022-08-13 22:27:02","TRT02EDTM":"2023-08-14 04:27:02","AP01SDTM":"2020-08-13 10:27:02","AP01EDTM":"2022-08-13 22:27:02","AP02SDTM":"2022-08-13 22:27:02","AP02EDTM":"2023-08-14 04:27:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-14","EOSDY":1096,"LSTALVDT":"2023-08-27","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3219,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.58972,"AVALU":"mg/L","BASE2":7.86615,"BASE":9.19377,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.72356,"PCHG2":21.91114,"CHG":0.39595,"PCHG":4.30671,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-21 10:27:02","ADY":922,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-6-id-369","SUBJID":"id-369","SITEID":"BRA-6","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-6","INVNAM":"Dr. BRA-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":5.41359,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-09","TRTSDTM":"2020-08-13 10:27:02","TRTEDTM":"2023-08-14 04:27:02","TRT01SDTM":"2020-08-13 10:27:02","TRT01EDTM":"2022-08-13 22:27:02","TRT02SDTM":"2022-08-13 22:27:02","TRT02EDTM":"2023-08-14 04:27:02","AP01SDTM":"2020-08-13 10:27:02","AP01EDTM":"2022-08-13 22:27:02","AP02SDTM":"2022-08-13 22:27:02","AP02EDTM":"2023-08-14 04:27:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-14","EOSDY":1096,"LSTALVDT":"2023-08-27","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5654,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88901,"AVALU":"g/L","BASE2":2.88901,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-25 10:27:02","ADY":134,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-6-id-369","SUBJID":"id-369","SITEID":"BRA-6","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-6","INVNAM":"Dr. BRA-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":5.41359,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-09","TRTSDTM":"2020-08-13 10:27:02","TRTEDTM":"2023-08-14 04:27:02","TRT01SDTM":"2020-08-13 10:27:02","TRT01EDTM":"2022-08-13 22:27:02","TRT02SDTM":"2022-08-13 22:27:02","TRT02EDTM":"2023-08-14 04:27:02","AP01SDTM":"2020-08-13 10:27:02","AP01EDTM":"2022-08-13 22:27:02","AP02SDTM":"2022-08-13 22:27:02","AP02EDTM":"2023-08-14 04:27:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-14","EOSDY":1096,"LSTALVDT":"2023-08-27","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4226,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.71405,"AVALU":"g/L","BASE2":2.88901,"BASE":2.71405,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.17496,"PCHG2":-6.05603,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-02 10:27:02","ADY":566,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-6-id-369","SUBJID":"id-369","SITEID":"BRA-6","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-6","INVNAM":"Dr. BRA-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":5.41359,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-09","TRTSDTM":"2020-08-13 10:27:02","TRTEDTM":"2023-08-14 04:27:02","TRT01SDTM":"2020-08-13 10:27:02","TRT01EDTM":"2022-08-13 22:27:02","TRT02SDTM":"2022-08-13 22:27:02","TRT02EDTM":"2023-08-14 04:27:02","AP01SDTM":"2020-08-13 10:27:02","AP01EDTM":"2022-08-13 22:27:02","AP02SDTM":"2022-08-13 22:27:02","AP02EDTM":"2023-08-14 04:27:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-14","EOSDY":1096,"LSTALVDT":"2023-08-27","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5420,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79958,"AVALU":"g/L","BASE2":2.88901,"BASE":2.71405,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08942,"PCHG2":-3.09535,"CHG":0.08553,"PCHG":3.15154,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-06 10:27:02","ADY":570,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-6-id-369","SUBJID":"id-369","SITEID":"BRA-6","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-6","INVNAM":"Dr. BRA-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":5.41359,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-09","TRTSDTM":"2020-08-13 10:27:02","TRTEDTM":"2023-08-14 04:27:02","TRT01SDTM":"2020-08-13 10:27:02","TRT01EDTM":"2022-08-13 22:27:02","TRT02SDTM":"2022-08-13 22:27:02","TRT02EDTM":"2023-08-14 04:27:02","AP01SDTM":"2020-08-13 10:27:02","AP01EDTM":"2022-08-13 22:27:02","AP02SDTM":"2022-08-13 22:27:02","AP02EDTM":"2023-08-14 04:27:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-14","EOSDY":1096,"LSTALVDT":"2023-08-27","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6380,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02513,"AVALU":"g/L","BASE2":2.88901,"BASE":2.71405,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13613,"PCHG2":4.71186,"CHG":0.31108,"PCHG":11.46204,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-03-29 10:27:02","ADY":593,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-6-id-369","SUBJID":"id-369","SITEID":"BRA-6","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-6","INVNAM":"Dr. BRA-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":5.41359,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-09","TRTSDTM":"2020-08-13 10:27:02","TRTEDTM":"2023-08-14 04:27:02","TRT01SDTM":"2020-08-13 10:27:02","TRT01EDTM":"2022-08-13 22:27:02","TRT02SDTM":"2022-08-13 22:27:02","TRT02EDTM":"2023-08-14 04:27:02","AP01SDTM":"2020-08-13 10:27:02","AP01EDTM":"2022-08-13 22:27:02","AP02SDTM":"2022-08-13 22:27:02","AP02EDTM":"2023-08-14 04:27:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-14","EOSDY":1096,"LSTALVDT":"2023-08-27","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5621,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9242,"AVALU":"g/L","BASE2":2.88901,"BASE":2.71405,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0352,"PCHG2":1.21828,"CHG":0.21016,"PCHG":7.74324,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-19 10:27:02","ADY":736,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-6-id-369","SUBJID":"id-369","SITEID":"BRA-6","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-6","INVNAM":"Dr. BRA-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":5.41359,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-09","TRTSDTM":"2020-08-13 10:27:02","TRTEDTM":"2023-08-14 04:27:02","TRT01SDTM":"2020-08-13 10:27:02","TRT01EDTM":"2022-08-13 22:27:02","TRT02SDTM":"2022-08-13 22:27:02","TRT02EDTM":"2023-08-14 04:27:02","AP01SDTM":"2020-08-13 10:27:02","AP01EDTM":"2022-08-13 22:27:02","AP02SDTM":"2022-08-13 22:27:02","AP02EDTM":"2023-08-14 04:27:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-14","EOSDY":1096,"LSTALVDT":"2023-08-27","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3921,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87347,"AVALU":"g/L","BASE2":2.88901,"BASE":2.71405,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01553,"PCHG2":-0.53763,"CHG":0.15943,"PCHG":5.87414,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-03 10:27:02","ADY":812,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-6-id-369","SUBJID":"id-369","SITEID":"BRA-6","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-6","INVNAM":"Dr. BRA-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"A","STRATA2":"S1","BMRKR1":5.41359,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-09","TRTSDTM":"2020-08-13 10:27:02","TRTEDTM":"2023-08-14 04:27:02","TRT01SDTM":"2020-08-13 10:27:02","TRT01EDTM":"2022-08-13 22:27:02","TRT02SDTM":"2022-08-13 22:27:02","TRT02EDTM":"2023-08-14 04:27:02","AP01SDTM":"2020-08-13 10:27:02","AP01EDTM":"2022-08-13 22:27:02","AP02SDTM":"2022-08-13 22:27:02","AP02EDTM":"2023-08-14 04:27:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-14","EOSDY":1096,"LSTALVDT":"2023-08-27","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5406,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.65565,"AVALU":"g/L","BASE2":2.88901,"BASE":2.71405,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.23336,"PCHG2":-8.07749,"CHG":-0.0584,"PCHG":-2.15177,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-21 10:27:02","ADY":922,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-7-id-301","SUBJID":"id-301","SITEID":"BRA-7","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-7","INVNAM":"Dr. BRA-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":10.52061,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-21","TRTSDTM":"2019-07-25 03:32:13","TRTEDTM":"2022-07-24 21:32:13","TRT01SDTM":"2019-07-25 03:32:13","TRT01EDTM":"2021-07-24 15:32:13","TRT02SDTM":"2021-07-24 15:32:13","TRT02EDTM":"2022-07-24 21:32:13","AP01SDTM":"2019-07-25 03:32:13","AP01EDTM":"2021-07-24 15:32:13","AP02SDTM":"2021-07-24 15:32:13","AP02EDTM":"2022-07-24 21:32:13","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-24","EOSDY":1096,"LSTALVDT":"2022-08-10","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7959,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.65902,"AVALU":"U/L","BASE2":8.65902,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-27 03:32:13","ADY":2,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-7-id-301","SUBJID":"id-301","SITEID":"BRA-7","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-7","INVNAM":"Dr. BRA-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":10.52061,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-21","TRTSDTM":"2019-07-25 03:32:13","TRTEDTM":"2022-07-24 21:32:13","TRT01SDTM":"2019-07-25 03:32:13","TRT01EDTM":"2021-07-24 15:32:13","TRT02SDTM":"2021-07-24 15:32:13","TRT02EDTM":"2022-07-24 21:32:13","AP01SDTM":"2019-07-25 03:32:13","AP01EDTM":"2021-07-24 15:32:13","AP02SDTM":"2021-07-24 15:32:13","AP02EDTM":"2022-07-24 21:32:13","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-24","EOSDY":1096,"LSTALVDT":"2022-08-10","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1995,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.22258,"AVALU":"U/L","BASE2":8.65902,"BASE":8.22258,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.43644,"PCHG2":-5.04033,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-02 03:32:13","ADY":69,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-7-id-301","SUBJID":"id-301","SITEID":"BRA-7","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-7","INVNAM":"Dr. BRA-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":10.52061,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-21","TRTSDTM":"2019-07-25 03:32:13","TRTEDTM":"2022-07-24 21:32:13","TRT01SDTM":"2019-07-25 03:32:13","TRT01EDTM":"2021-07-24 15:32:13","TRT02SDTM":"2021-07-24 15:32:13","TRT02EDTM":"2022-07-24 21:32:13","AP01SDTM":"2019-07-25 03:32:13","AP01EDTM":"2021-07-24 15:32:13","AP02SDTM":"2021-07-24 15:32:13","AP02EDTM":"2022-07-24 21:32:13","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-24","EOSDY":1096,"LSTALVDT":"2022-08-10","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7078,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":38.962,"AVALU":"U/L","BASE2":8.65902,"BASE":8.22258,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":30.30298,"PCHG2":349.95838,"CHG":30.73942,"PCHG":373.84154,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-27 03:32:13","ADY":583,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-7-id-301","SUBJID":"id-301","SITEID":"BRA-7","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-7","INVNAM":"Dr. BRA-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":10.52061,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-21","TRTSDTM":"2019-07-25 03:32:13","TRTEDTM":"2022-07-24 21:32:13","TRT01SDTM":"2019-07-25 03:32:13","TRT01EDTM":"2021-07-24 15:32:13","TRT02SDTM":"2021-07-24 15:32:13","TRT02EDTM":"2022-07-24 21:32:13","AP01SDTM":"2019-07-25 03:32:13","AP01EDTM":"2021-07-24 15:32:13","AP02SDTM":"2021-07-24 15:32:13","AP02EDTM":"2022-07-24 21:32:13","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-24","EOSDY":1096,"LSTALVDT":"2022-08-10","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2275,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.19803,"AVALU":"U/L","BASE2":8.65902,"BASE":8.22258,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":23.539,"PCHG2":271.84363,"CHG":23.97545,"PCHG":291.58057,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-18 03:32:13","ADY":663,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-7-id-301","SUBJID":"id-301","SITEID":"BRA-7","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-7","INVNAM":"Dr. BRA-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":10.52061,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-21","TRTSDTM":"2019-07-25 03:32:13","TRTEDTM":"2022-07-24 21:32:13","TRT01SDTM":"2019-07-25 03:32:13","TRT01EDTM":"2021-07-24 15:32:13","TRT02SDTM":"2021-07-24 15:32:13","TRT02EDTM":"2022-07-24 21:32:13","AP01SDTM":"2019-07-25 03:32:13","AP01EDTM":"2021-07-24 15:32:13","AP02SDTM":"2021-07-24 15:32:13","AP02EDTM":"2022-07-24 21:32:13","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-24","EOSDY":1096,"LSTALVDT":"2022-08-10","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3724,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.63692,"AVALU":"U/L","BASE2":8.65902,"BASE":8.22258,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.9779,"PCHG2":172.97445,"CHG":15.41434,"PCHG":187.46355,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-18 03:32:13","ADY":755,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-7-id-301","SUBJID":"id-301","SITEID":"BRA-7","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-7","INVNAM":"Dr. BRA-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":10.52061,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-21","TRTSDTM":"2019-07-25 03:32:13","TRTEDTM":"2022-07-24 21:32:13","TRT01SDTM":"2019-07-25 03:32:13","TRT01EDTM":"2021-07-24 15:32:13","TRT02SDTM":"2021-07-24 15:32:13","TRT02EDTM":"2022-07-24 21:32:13","AP01SDTM":"2019-07-25 03:32:13","AP01EDTM":"2021-07-24 15:32:13","AP02SDTM":"2021-07-24 15:32:13","AP02EDTM":"2022-07-24 21:32:13","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-24","EOSDY":1096,"LSTALVDT":"2022-08-10","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7542,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.64708,"AVALU":"U/L","BASE2":8.65902,"BASE":8.22258,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.01194,"PCHG2":-34.78384,"CHG":-2.5755,"PCHG":-31.32226,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-09-25 03:32:13","ADY":793,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-7-id-301","SUBJID":"id-301","SITEID":"BRA-7","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-7","INVNAM":"Dr. BRA-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":10.52061,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-21","TRTSDTM":"2019-07-25 03:32:13","TRTEDTM":"2022-07-24 21:32:13","TRT01SDTM":"2019-07-25 03:32:13","TRT01EDTM":"2021-07-24 15:32:13","TRT02SDTM":"2021-07-24 15:32:13","TRT02EDTM":"2022-07-24 21:32:13","AP01SDTM":"2019-07-25 03:32:13","AP01EDTM":"2021-07-24 15:32:13","AP02SDTM":"2021-07-24 15:32:13","AP02EDTM":"2022-07-24 21:32:13","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-24","EOSDY":1096,"LSTALVDT":"2022-08-10","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":605,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.03214,"AVALU":"U/L","BASE2":8.65902,"BASE":8.22258,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.62688,"PCHG2":-53.43419,"CHG":-4.19044,"PCHG":-50.96254,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-07-11 03:32:13","ADY":1082,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-7-id-301","SUBJID":"id-301","SITEID":"BRA-7","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-7","INVNAM":"Dr. BRA-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":10.52061,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-21","TRTSDTM":"2019-07-25 03:32:13","TRTEDTM":"2022-07-24 21:32:13","TRT01SDTM":"2019-07-25 03:32:13","TRT01EDTM":"2021-07-24 15:32:13","TRT02SDTM":"2021-07-24 15:32:13","TRT02EDTM":"2022-07-24 21:32:13","AP01SDTM":"2019-07-25 03:32:13","AP01EDTM":"2021-07-24 15:32:13","AP02SDTM":"2021-07-24 15:32:13","AP02EDTM":"2022-07-24 21:32:13","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-24","EOSDY":1096,"LSTALVDT":"2022-08-10","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8167,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.29117,"AVALU":"mg/L","BASE2":10.29117,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"3","BTOXGR":"0","ADTM":"2019-07-27 03:32:13","ADY":2,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-7-id-301","SUBJID":"id-301","SITEID":"BRA-7","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-7","INVNAM":"Dr. BRA-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":10.52061,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-21","TRTSDTM":"2019-07-25 03:32:13","TRTEDTM":"2022-07-24 21:32:13","TRT01SDTM":"2019-07-25 03:32:13","TRT01EDTM":"2021-07-24 15:32:13","TRT02SDTM":"2021-07-24 15:32:13","TRT02EDTM":"2022-07-24 21:32:13","AP01SDTM":"2019-07-25 03:32:13","AP01EDTM":"2021-07-24 15:32:13","AP02SDTM":"2021-07-24 15:32:13","AP02EDTM":"2022-07-24 21:32:13","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-24","EOSDY":1096,"LSTALVDT":"2022-08-10","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5147,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.02207,"AVALU":"mg/L","BASE2":10.29117,"BASE":9.02207,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.2691,"PCHG2":-12.33191,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-02 03:32:13","ADY":69,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-7-id-301","SUBJID":"id-301","SITEID":"BRA-7","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-7","INVNAM":"Dr. BRA-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":10.52061,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-21","TRTSDTM":"2019-07-25 03:32:13","TRTEDTM":"2022-07-24 21:32:13","TRT01SDTM":"2019-07-25 03:32:13","TRT01EDTM":"2021-07-24 15:32:13","TRT02SDTM":"2021-07-24 15:32:13","TRT02EDTM":"2022-07-24 21:32:13","AP01SDTM":"2019-07-25 03:32:13","AP01EDTM":"2021-07-24 15:32:13","AP02SDTM":"2021-07-24 15:32:13","AP02EDTM":"2022-07-24 21:32:13","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-24","EOSDY":1096,"LSTALVDT":"2022-08-10","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":709,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.62957,"AVALU":"mg/L","BASE2":10.29117,"BASE":9.02207,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.6616,"PCHG2":-16.14587,"CHG":-0.3925,"PCHG":-4.35045,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-27 03:32:13","ADY":583,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-7-id-301","SUBJID":"id-301","SITEID":"BRA-7","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-7","INVNAM":"Dr. BRA-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":10.52061,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-21","TRTSDTM":"2019-07-25 03:32:13","TRTEDTM":"2022-07-24 21:32:13","TRT01SDTM":"2019-07-25 03:32:13","TRT01EDTM":"2021-07-24 15:32:13","TRT02SDTM":"2021-07-24 15:32:13","TRT02EDTM":"2022-07-24 21:32:13","AP01SDTM":"2019-07-25 03:32:13","AP01EDTM":"2021-07-24 15:32:13","AP02SDTM":"2021-07-24 15:32:13","AP02EDTM":"2022-07-24 21:32:13","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-24","EOSDY":1096,"LSTALVDT":"2022-08-10","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3453,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.20203,"AVALU":"mg/L","BASE2":10.29117,"BASE":9.02207,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.08914,"PCHG2":-10.58322,"CHG":0.17996,"PCHG":1.99468,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-18 03:32:13","ADY":663,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-7-id-301","SUBJID":"id-301","SITEID":"BRA-7","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-7","INVNAM":"Dr. BRA-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":10.52061,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-21","TRTSDTM":"2019-07-25 03:32:13","TRTEDTM":"2022-07-24 21:32:13","TRT01SDTM":"2019-07-25 03:32:13","TRT01EDTM":"2021-07-24 15:32:13","TRT02SDTM":"2021-07-24 15:32:13","TRT02EDTM":"2022-07-24 21:32:13","AP01SDTM":"2019-07-25 03:32:13","AP01EDTM":"2021-07-24 15:32:13","AP02SDTM":"2021-07-24 15:32:13","AP02EDTM":"2022-07-24 21:32:13","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-24","EOSDY":1096,"LSTALVDT":"2022-08-10","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4663,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.204,"AVALU":"mg/L","BASE2":10.29117,"BASE":9.02207,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.08717,"PCHG2":-20.28122,"CHG":-0.81808,"PCHG":-9.0675,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-18 03:32:13","ADY":755,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-7-id-301","SUBJID":"id-301","SITEID":"BRA-7","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-7","INVNAM":"Dr. BRA-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":10.52061,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-21","TRTSDTM":"2019-07-25 03:32:13","TRTEDTM":"2022-07-24 21:32:13","TRT01SDTM":"2019-07-25 03:32:13","TRT01EDTM":"2021-07-24 15:32:13","TRT02SDTM":"2021-07-24 15:32:13","TRT02EDTM":"2022-07-24 21:32:13","AP01SDTM":"2019-07-25 03:32:13","AP01EDTM":"2021-07-24 15:32:13","AP02SDTM":"2021-07-24 15:32:13","AP02EDTM":"2022-07-24 21:32:13","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-24","EOSDY":1096,"LSTALVDT":"2022-08-10","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5890,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.88627,"AVALU":"mg/L","BASE2":10.29117,"BASE":9.02207,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.4049,"PCHG2":-23.3686,"CHG":-1.1358,"PCHG":-12.58917,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-09-25 03:32:13","ADY":793,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-7-id-301","SUBJID":"id-301","SITEID":"BRA-7","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-7","INVNAM":"Dr. BRA-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":10.52061,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-21","TRTSDTM":"2019-07-25 03:32:13","TRTEDTM":"2022-07-24 21:32:13","TRT01SDTM":"2019-07-25 03:32:13","TRT01EDTM":"2021-07-24 15:32:13","TRT02SDTM":"2021-07-24 15:32:13","TRT02EDTM":"2022-07-24 21:32:13","AP01SDTM":"2019-07-25 03:32:13","AP01EDTM":"2021-07-24 15:32:13","AP02SDTM":"2021-07-24 15:32:13","AP02EDTM":"2022-07-24 21:32:13","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-24","EOSDY":1096,"LSTALVDT":"2022-08-10","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6745,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.18195,"AVALU":"mg/L","BASE2":10.29117,"BASE":9.02207,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.10922,"PCHG2":-20.49548,"CHG":-0.84013,"PCHG":-9.3119,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-11 03:32:13","ADY":1082,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-7-id-301","SUBJID":"id-301","SITEID":"BRA-7","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-7","INVNAM":"Dr. BRA-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":10.52061,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-21","TRTSDTM":"2019-07-25 03:32:13","TRTEDTM":"2022-07-24 21:32:13","TRT01SDTM":"2019-07-25 03:32:13","TRT01EDTM":"2021-07-24 15:32:13","TRT02SDTM":"2021-07-24 15:32:13","TRT02EDTM":"2022-07-24 21:32:13","AP01SDTM":"2019-07-25 03:32:13","AP01EDTM":"2021-07-24 15:32:13","AP02SDTM":"2021-07-24 15:32:13","AP02EDTM":"2022-07-24 21:32:13","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-24","EOSDY":1096,"LSTALVDT":"2022-08-10","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5630,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88704,"AVALU":"g/L","BASE2":2.88704,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"2","ADTM":"2019-07-27 03:32:13","ADY":2,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-7-id-301","SUBJID":"id-301","SITEID":"BRA-7","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-7","INVNAM":"Dr. BRA-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":10.52061,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-21","TRTSDTM":"2019-07-25 03:32:13","TRTEDTM":"2022-07-24 21:32:13","TRT01SDTM":"2019-07-25 03:32:13","TRT01EDTM":"2021-07-24 15:32:13","TRT02SDTM":"2021-07-24 15:32:13","TRT02EDTM":"2022-07-24 21:32:13","AP01SDTM":"2019-07-25 03:32:13","AP01EDTM":"2021-07-24 15:32:13","AP02SDTM":"2021-07-24 15:32:13","AP02EDTM":"2022-07-24 21:32:13","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-24","EOSDY":1096,"LSTALVDT":"2022-08-10","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4413,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.14263,"AVALU":"g/L","BASE2":2.88704,"BASE":3.14263,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.2556,"PCHG2":8.85319,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2019-10-02 03:32:13","ADY":69,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-7-id-301","SUBJID":"id-301","SITEID":"BRA-7","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-7","INVNAM":"Dr. BRA-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":10.52061,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-21","TRTSDTM":"2019-07-25 03:32:13","TRTEDTM":"2022-07-24 21:32:13","TRT01SDTM":"2019-07-25 03:32:13","TRT01EDTM":"2021-07-24 15:32:13","TRT02SDTM":"2021-07-24 15:32:13","TRT02EDTM":"2022-07-24 21:32:13","AP01SDTM":"2019-07-25 03:32:13","AP01EDTM":"2021-07-24 15:32:13","AP02SDTM":"2021-07-24 15:32:13","AP02EDTM":"2022-07-24 21:32:13","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-24","EOSDY":1096,"LSTALVDT":"2022-08-10","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5221,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90458,"AVALU":"g/L","BASE2":2.88704,"BASE":3.14263,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01754,"PCHG2":0.60771,"CHG":-0.23805,"PCHG":-7.57487,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-02-27 03:32:13","ADY":583,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-7-id-301","SUBJID":"id-301","SITEID":"BRA-7","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-7","INVNAM":"Dr. BRA-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":10.52061,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-21","TRTSDTM":"2019-07-25 03:32:13","TRTEDTM":"2022-07-24 21:32:13","TRT01SDTM":"2019-07-25 03:32:13","TRT01EDTM":"2021-07-24 15:32:13","TRT02SDTM":"2021-07-24 15:32:13","TRT02EDTM":"2022-07-24 21:32:13","AP01SDTM":"2019-07-25 03:32:13","AP01EDTM":"2021-07-24 15:32:13","AP02SDTM":"2021-07-24 15:32:13","AP02EDTM":"2022-07-24 21:32:13","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-24","EOSDY":1096,"LSTALVDT":"2022-08-10","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3653,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74391,"AVALU":"g/L","BASE2":2.88704,"BASE":3.14263,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14313,"PCHG2":-4.95781,"CHG":-0.39873,"PCHG":-12.68774,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-05-18 03:32:13","ADY":663,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-7-id-301","SUBJID":"id-301","SITEID":"BRA-7","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-7","INVNAM":"Dr. BRA-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":10.52061,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-21","TRTSDTM":"2019-07-25 03:32:13","TRTEDTM":"2022-07-24 21:32:13","TRT01SDTM":"2019-07-25 03:32:13","TRT01EDTM":"2021-07-24 15:32:13","TRT02SDTM":"2021-07-24 15:32:13","TRT02EDTM":"2022-07-24 21:32:13","AP01SDTM":"2019-07-25 03:32:13","AP01EDTM":"2021-07-24 15:32:13","AP02SDTM":"2021-07-24 15:32:13","AP02EDTM":"2022-07-24 21:32:13","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-24","EOSDY":1096,"LSTALVDT":"2022-08-10","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5987,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92113,"AVALU":"g/L","BASE2":2.88704,"BASE":3.14263,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03409,"PCHG2":1.18065,"CHG":-0.22151,"PCHG":-7.04852,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-08-18 03:32:13","ADY":755,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-7-id-301","SUBJID":"id-301","SITEID":"BRA-7","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-7","INVNAM":"Dr. BRA-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":10.52061,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-21","TRTSDTM":"2019-07-25 03:32:13","TRTEDTM":"2022-07-24 21:32:13","TRT01SDTM":"2019-07-25 03:32:13","TRT01EDTM":"2021-07-24 15:32:13","TRT02SDTM":"2021-07-24 15:32:13","TRT02EDTM":"2022-07-24 21:32:13","AP01SDTM":"2019-07-25 03:32:13","AP01EDTM":"2021-07-24 15:32:13","AP02SDTM":"2021-07-24 15:32:13","AP02EDTM":"2022-07-24 21:32:13","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-24","EOSDY":1096,"LSTALVDT":"2022-08-10","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2140,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0941,"AVALU":"g/L","BASE2":2.88704,"BASE":3.14263,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.20706,"PCHG2":7.17218,"CHG":-0.04853,"PCHG":-1.54429,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"1","BTOXGR":"2","ADTM":"2021-09-25 03:32:13","ADY":793,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-BRA-7-id-301","SUBJID":"id-301","SITEID":"BRA-7","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"BRA","DTHFL":"N","INVID":"INV ID BRA-7","INVNAM":"Dr. BRA-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"South America","STRATA1":"B","STRATA2":"S2","BMRKR1":10.52061,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-21","TRTSDTM":"2019-07-25 03:32:13","TRTEDTM":"2022-07-24 21:32:13","TRT01SDTM":"2019-07-25 03:32:13","TRT01EDTM":"2021-07-24 15:32:13","TRT02SDTM":"2021-07-24 15:32:13","TRT02EDTM":"2022-07-24 21:32:13","AP01SDTM":"2019-07-25 03:32:13","AP01EDTM":"2021-07-24 15:32:13","AP02SDTM":"2021-07-24 15:32:13","AP02EDTM":"2022-07-24 21:32:13","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-24","EOSDY":1096,"LSTALVDT":"2022-08-10","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":357,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.62462,"AVALU":"g/L","BASE2":2.88704,"BASE":3.14263,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.26242,"PCHG2":-9.08961,"CHG":-0.51802,"PCHG":-16.48349,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-07-11 03:32:13","ADY":1082,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-18","SUBJID":"id-18","SITEID":"CAN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.47872,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-30","TRTSDTM":"2021-01-02 02:01:15","TRTEDTM":"2024-01-02 20:01:15","TRT01SDTM":"2021-01-02 02:01:15","TRT01EDTM":"2023-01-02 14:01:15","TRT02SDTM":"2023-01-02 14:01:15","TRT02EDTM":"2024-01-02 20:01:15","AP01SDTM":"2021-01-02 02:01:15","AP01EDTM":"2023-01-02 14:01:15","AP02SDTM":"2023-01-02 14:01:15","AP02EDTM":"2024-01-02 20:01:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-02","EOSDY":1096,"LSTALVDT":"2024-01-24","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6906,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.91691,"AVALU":"U/L","BASE2":17.91691,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-27 02:01:15","ADY":56,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-18","SUBJID":"id-18","SITEID":"CAN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.47872,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-30","TRTSDTM":"2021-01-02 02:01:15","TRTEDTM":"2024-01-02 20:01:15","TRT01SDTM":"2021-01-02 02:01:15","TRT01EDTM":"2023-01-02 14:01:15","TRT02SDTM":"2023-01-02 14:01:15","TRT02EDTM":"2024-01-02 20:01:15","AP01SDTM":"2021-01-02 02:01:15","AP01EDTM":"2023-01-02 14:01:15","AP02SDTM":"2023-01-02 14:01:15","AP02EDTM":"2024-01-02 20:01:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-02","EOSDY":1096,"LSTALVDT":"2024-01-24","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2105,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.7065,"AVALU":"U/L","BASE2":17.91691,"BASE":12.7065,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-5.21041,"PCHG2":-29.08096,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-02 02:01:15","ADY":151,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-18","SUBJID":"id-18","SITEID":"CAN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.47872,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-30","TRTSDTM":"2021-01-02 02:01:15","TRTEDTM":"2024-01-02 20:01:15","TRT01SDTM":"2021-01-02 02:01:15","TRT01EDTM":"2023-01-02 14:01:15","TRT02SDTM":"2023-01-02 14:01:15","TRT02EDTM":"2024-01-02 20:01:15","AP01SDTM":"2021-01-02 02:01:15","AP01EDTM":"2023-01-02 14:01:15","AP02SDTM":"2023-01-02 14:01:15","AP02EDTM":"2024-01-02 20:01:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-02","EOSDY":1096,"LSTALVDT":"2024-01-24","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3645,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.47416,"AVALU":"U/L","BASE2":17.91691,"BASE":12.7065,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.44275,"PCHG2":-24.79642,"CHG":0.76766,"PCHG":6.04145,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-19 02:01:15","ADY":351,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-18","SUBJID":"id-18","SITEID":"CAN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.47872,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-30","TRTSDTM":"2021-01-02 02:01:15","TRTEDTM":"2024-01-02 20:01:15","TRT01SDTM":"2021-01-02 02:01:15","TRT01EDTM":"2023-01-02 14:01:15","TRT02SDTM":"2023-01-02 14:01:15","TRT02EDTM":"2024-01-02 20:01:15","AP01SDTM":"2021-01-02 02:01:15","AP01EDTM":"2023-01-02 14:01:15","AP02SDTM":"2023-01-02 14:01:15","AP02EDTM":"2024-01-02 20:01:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-02","EOSDY":1096,"LSTALVDT":"2024-01-24","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":551,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.8408,"AVALU":"U/L","BASE2":17.91691,"BASE":12.7065,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.07611,"PCHG2":-89.72591,"CHG":-10.8657,"PCHG":-85.51293,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-04-12 02:01:15","ADY":465,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-18","SUBJID":"id-18","SITEID":"CAN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.47872,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-30","TRTSDTM":"2021-01-02 02:01:15","TRTEDTM":"2024-01-02 20:01:15","TRT01SDTM":"2021-01-02 02:01:15","TRT01EDTM":"2023-01-02 14:01:15","TRT02SDTM":"2023-01-02 14:01:15","TRT02EDTM":"2024-01-02 20:01:15","AP01SDTM":"2021-01-02 02:01:15","AP01EDTM":"2023-01-02 14:01:15","AP02SDTM":"2023-01-02 14:01:15","AP02EDTM":"2024-01-02 20:01:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-02","EOSDY":1096,"LSTALVDT":"2024-01-24","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2669,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.8148,"AVALU":"U/L","BASE2":17.91691,"BASE":12.7065,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.10211,"PCHG2":-11.73254,"CHG":3.1083,"PCHG":24.46228,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-03 02:01:15","ADY":547,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-18","SUBJID":"id-18","SITEID":"CAN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.47872,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-30","TRTSDTM":"2021-01-02 02:01:15","TRTEDTM":"2024-01-02 20:01:15","TRT01SDTM":"2021-01-02 02:01:15","TRT01EDTM":"2023-01-02 14:01:15","TRT02SDTM":"2023-01-02 14:01:15","TRT02EDTM":"2024-01-02 20:01:15","AP01SDTM":"2021-01-02 02:01:15","AP01EDTM":"2023-01-02 14:01:15","AP02SDTM":"2023-01-02 14:01:15","AP02EDTM":"2024-01-02 20:01:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-02","EOSDY":1096,"LSTALVDT":"2024-01-24","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":82,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":48.30035,"AVALU":"U/L","BASE2":17.91691,"BASE":12.7065,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":30.38344,"PCHG2":169.5797,"CHG":35.59385,"PCHG":280.12315,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-17 02:01:15","ADY":926,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-18","SUBJID":"id-18","SITEID":"CAN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.47872,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-30","TRTSDTM":"2021-01-02 02:01:15","TRTEDTM":"2024-01-02 20:01:15","TRT01SDTM":"2021-01-02 02:01:15","TRT01EDTM":"2023-01-02 14:01:15","TRT02SDTM":"2023-01-02 14:01:15","TRT02EDTM":"2024-01-02 20:01:15","AP01SDTM":"2021-01-02 02:01:15","AP01EDTM":"2023-01-02 14:01:15","AP02SDTM":"2023-01-02 14:01:15","AP02EDTM":"2024-01-02 20:01:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-02","EOSDY":1096,"LSTALVDT":"2024-01-24","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1768,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.7067,"AVALU":"U/L","BASE2":17.91691,"BASE":12.7065,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.78979,"PCHG2":32.31464,"CHG":11.00019,"PCHG":86.57139,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-27 02:01:15","ADY":967,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-18","SUBJID":"id-18","SITEID":"CAN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.47872,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-30","TRTSDTM":"2021-01-02 02:01:15","TRTEDTM":"2024-01-02 20:01:15","TRT01SDTM":"2021-01-02 02:01:15","TRT01EDTM":"2023-01-02 14:01:15","TRT02SDTM":"2023-01-02 14:01:15","TRT02EDTM":"2024-01-02 20:01:15","AP01SDTM":"2021-01-02 02:01:15","AP01EDTM":"2023-01-02 14:01:15","AP02SDTM":"2023-01-02 14:01:15","AP02EDTM":"2024-01-02 20:01:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-02","EOSDY":1096,"LSTALVDT":"2024-01-24","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3782,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.7496,"AVALU":"mg/L","BASE2":7.7496,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-4","BTOXGR":"-2","ADTM":"2021-02-27 02:01:15","ADY":56,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-18","SUBJID":"id-18","SITEID":"CAN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.47872,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-30","TRTSDTM":"2021-01-02 02:01:15","TRTEDTM":"2024-01-02 20:01:15","TRT01SDTM":"2021-01-02 02:01:15","TRT01EDTM":"2023-01-02 14:01:15","TRT02SDTM":"2023-01-02 14:01:15","TRT02EDTM":"2024-01-02 20:01:15","AP01SDTM":"2021-01-02 02:01:15","AP01EDTM":"2023-01-02 14:01:15","AP02SDTM":"2023-01-02 14:01:15","AP02EDTM":"2024-01-02 20:01:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-02","EOSDY":1096,"LSTALVDT":"2024-01-24","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2798,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.82223,"AVALU":"mg/L","BASE2":7.7496,"BASE":7.82223,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.07263,"PCHG2":0.93717,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2021-06-02 02:01:15","ADY":151,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-18","SUBJID":"id-18","SITEID":"CAN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.47872,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-30","TRTSDTM":"2021-01-02 02:01:15","TRTEDTM":"2024-01-02 20:01:15","TRT01SDTM":"2021-01-02 02:01:15","TRT01EDTM":"2023-01-02 14:01:15","TRT02SDTM":"2023-01-02 14:01:15","TRT02EDTM":"2024-01-02 20:01:15","AP01SDTM":"2021-01-02 02:01:15","AP01EDTM":"2023-01-02 14:01:15","AP02SDTM":"2023-01-02 14:01:15","AP02EDTM":"2024-01-02 20:01:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-02","EOSDY":1096,"LSTALVDT":"2024-01-24","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7920,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.71235,"AVALU":"mg/L","BASE2":7.7496,"BASE":7.82223,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.96275,"PCHG2":25.32713,"CHG":1.89012,"PCHG":24.16351,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-12-19 02:01:15","ADY":351,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-18","SUBJID":"id-18","SITEID":"CAN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.47872,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-30","TRTSDTM":"2021-01-02 02:01:15","TRTEDTM":"2024-01-02 20:01:15","TRT01SDTM":"2021-01-02 02:01:15","TRT01EDTM":"2023-01-02 14:01:15","TRT02SDTM":"2023-01-02 14:01:15","TRT02EDTM":"2024-01-02 20:01:15","AP01SDTM":"2021-01-02 02:01:15","AP01EDTM":"2023-01-02 14:01:15","AP02SDTM":"2023-01-02 14:01:15","AP02EDTM":"2024-01-02 20:01:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-02","EOSDY":1096,"LSTALVDT":"2024-01-24","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4926,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.51822,"AVALU":"mg/L","BASE2":7.7496,"BASE":7.82223,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.76862,"PCHG2":22.82209,"CHG":1.69599,"PCHG":21.68173,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-04-12 02:01:15","ADY":465,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-18","SUBJID":"id-18","SITEID":"CAN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.47872,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-30","TRTSDTM":"2021-01-02 02:01:15","TRTEDTM":"2024-01-02 20:01:15","TRT01SDTM":"2021-01-02 02:01:15","TRT01EDTM":"2023-01-02 14:01:15","TRT02SDTM":"2023-01-02 14:01:15","TRT02EDTM":"2024-01-02 20:01:15","AP01SDTM":"2021-01-02 02:01:15","AP01EDTM":"2023-01-02 14:01:15","AP02SDTM":"2023-01-02 14:01:15","AP02EDTM":"2024-01-02 20:01:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-02","EOSDY":1096,"LSTALVDT":"2024-01-24","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6478,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.53619,"AVALU":"mg/L","BASE2":7.7496,"BASE":7.82223,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.78659,"PCHG2":35.9579,"CHG":2.71397,"PCHG":34.69557,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"2","BTOXGR":"-2","ADTM":"2022-07-03 02:01:15","ADY":547,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-18","SUBJID":"id-18","SITEID":"CAN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.47872,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-30","TRTSDTM":"2021-01-02 02:01:15","TRTEDTM":"2024-01-02 20:01:15","TRT01SDTM":"2021-01-02 02:01:15","TRT01EDTM":"2023-01-02 14:01:15","TRT02SDTM":"2023-01-02 14:01:15","TRT02EDTM":"2024-01-02 20:01:15","AP01SDTM":"2021-01-02 02:01:15","AP01EDTM":"2023-01-02 14:01:15","AP02SDTM":"2023-01-02 14:01:15","AP02EDTM":"2024-01-02 20:01:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-02","EOSDY":1096,"LSTALVDT":"2024-01-24","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":990,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.97088,"AVALU":"mg/L","BASE2":7.7496,"BASE":7.82223,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.22128,"PCHG2":2.85539,"CHG":0.14865,"PCHG":1.90041,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-2","ADTM":"2023-07-17 02:01:15","ADY":926,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-18","SUBJID":"id-18","SITEID":"CAN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.47872,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-30","TRTSDTM":"2021-01-02 02:01:15","TRTEDTM":"2024-01-02 20:01:15","TRT01SDTM":"2021-01-02 02:01:15","TRT01EDTM":"2023-01-02 14:01:15","TRT02SDTM":"2023-01-02 14:01:15","TRT02EDTM":"2024-01-02 20:01:15","AP01SDTM":"2021-01-02 02:01:15","AP01EDTM":"2023-01-02 14:01:15","AP02SDTM":"2023-01-02 14:01:15","AP02EDTM":"2024-01-02 20:01:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-02","EOSDY":1096,"LSTALVDT":"2024-01-24","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3755,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.47884,"AVALU":"mg/L","BASE2":7.7496,"BASE":7.82223,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.72924,"PCHG2":35.2178,"CHG":2.65661,"PCHG":33.96235,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"4","BTOXGR":"-2","ADTM":"2023-08-27 02:01:15","ADY":967,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-18","SUBJID":"id-18","SITEID":"CAN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.47872,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-30","TRTSDTM":"2021-01-02 02:01:15","TRTEDTM":"2024-01-02 20:01:15","TRT01SDTM":"2021-01-02 02:01:15","TRT01EDTM":"2023-01-02 14:01:15","TRT02SDTM":"2023-01-02 14:01:15","TRT02EDTM":"2024-01-02 20:01:15","AP01SDTM":"2021-01-02 02:01:15","AP01EDTM":"2023-01-02 14:01:15","AP02SDTM":"2023-01-02 14:01:15","AP02EDTM":"2024-01-02 20:01:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-02","EOSDY":1096,"LSTALVDT":"2024-01-24","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3103,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93854,"AVALU":"g/L","BASE2":2.93854,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-27 02:01:15","ADY":56,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-18","SUBJID":"id-18","SITEID":"CAN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.47872,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-30","TRTSDTM":"2021-01-02 02:01:15","TRTEDTM":"2024-01-02 20:01:15","TRT01SDTM":"2021-01-02 02:01:15","TRT01EDTM":"2023-01-02 14:01:15","TRT02SDTM":"2023-01-02 14:01:15","TRT02EDTM":"2024-01-02 20:01:15","AP01SDTM":"2021-01-02 02:01:15","AP01EDTM":"2023-01-02 14:01:15","AP02SDTM":"2023-01-02 14:01:15","AP02EDTM":"2024-01-02 20:01:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-02","EOSDY":1096,"LSTALVDT":"2024-01-24","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3924,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88301,"AVALU":"g/L","BASE2":2.93854,"BASE":2.88301,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.05553,"PCHG2":-1.88968,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-02 02:01:15","ADY":151,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-18","SUBJID":"id-18","SITEID":"CAN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.47872,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-30","TRTSDTM":"2021-01-02 02:01:15","TRTEDTM":"2024-01-02 20:01:15","TRT01SDTM":"2021-01-02 02:01:15","TRT01EDTM":"2023-01-02 14:01:15","TRT02SDTM":"2023-01-02 14:01:15","TRT02EDTM":"2024-01-02 20:01:15","AP01SDTM":"2021-01-02 02:01:15","AP01EDTM":"2023-01-02 14:01:15","AP02SDTM":"2023-01-02 14:01:15","AP02EDTM":"2024-01-02 20:01:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-02","EOSDY":1096,"LSTALVDT":"2024-01-24","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7870,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.20721,"AVALU":"g/L","BASE2":2.93854,"BASE":2.88301,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.26867,"PCHG2":9.14296,"CHG":0.3242,"PCHG":11.24514,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-12-19 02:01:15","ADY":351,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-18","SUBJID":"id-18","SITEID":"CAN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.47872,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-30","TRTSDTM":"2021-01-02 02:01:15","TRTEDTM":"2024-01-02 20:01:15","TRT01SDTM":"2021-01-02 02:01:15","TRT01EDTM":"2023-01-02 14:01:15","TRT02SDTM":"2023-01-02 14:01:15","TRT02EDTM":"2024-01-02 20:01:15","AP01SDTM":"2021-01-02 02:01:15","AP01EDTM":"2023-01-02 14:01:15","AP02SDTM":"2023-01-02 14:01:15","AP02EDTM":"2024-01-02 20:01:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-02","EOSDY":1096,"LSTALVDT":"2024-01-24","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6996,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95,"AVALU":"g/L","BASE2":2.93854,"BASE":2.88301,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01146,"PCHG2":0.39011,"CHG":0.06699,"PCHG":2.32369,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-12 02:01:15","ADY":465,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-18","SUBJID":"id-18","SITEID":"CAN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.47872,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-30","TRTSDTM":"2021-01-02 02:01:15","TRTEDTM":"2024-01-02 20:01:15","TRT01SDTM":"2021-01-02 02:01:15","TRT01EDTM":"2023-01-02 14:01:15","TRT02SDTM":"2023-01-02 14:01:15","TRT02EDTM":"2024-01-02 20:01:15","AP01SDTM":"2021-01-02 02:01:15","AP01EDTM":"2023-01-02 14:01:15","AP02SDTM":"2023-01-02 14:01:15","AP02EDTM":"2024-01-02 20:01:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-02","EOSDY":1096,"LSTALVDT":"2024-01-24","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6678,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89877,"AVALU":"g/L","BASE2":2.93854,"BASE":2.88301,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03977,"PCHG2":-1.35339,"CHG":0.01576,"PCHG":0.54662,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-03 02:01:15","ADY":547,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-18","SUBJID":"id-18","SITEID":"CAN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.47872,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-30","TRTSDTM":"2021-01-02 02:01:15","TRTEDTM":"2024-01-02 20:01:15","TRT01SDTM":"2021-01-02 02:01:15","TRT01EDTM":"2023-01-02 14:01:15","TRT02SDTM":"2023-01-02 14:01:15","TRT02EDTM":"2024-01-02 20:01:15","AP01SDTM":"2021-01-02 02:01:15","AP01EDTM":"2023-01-02 14:01:15","AP02SDTM":"2023-01-02 14:01:15","AP02EDTM":"2024-01-02 20:01:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-02","EOSDY":1096,"LSTALVDT":"2024-01-24","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8093,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90009,"AVALU":"g/L","BASE2":2.93854,"BASE":2.88301,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03845,"PCHG2":-1.30835,"CHG":0.01708,"PCHG":0.59252,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-17 02:01:15","ADY":926,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-18","SUBJID":"id-18","SITEID":"CAN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":7.47872,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-30","TRTSDTM":"2021-01-02 02:01:15","TRTEDTM":"2024-01-02 20:01:15","TRT01SDTM":"2021-01-02 02:01:15","TRT01EDTM":"2023-01-02 14:01:15","TRT02SDTM":"2023-01-02 14:01:15","TRT02EDTM":"2024-01-02 20:01:15","AP01SDTM":"2021-01-02 02:01:15","AP01EDTM":"2023-01-02 14:01:15","AP02SDTM":"2023-01-02 14:01:15","AP02EDTM":"2024-01-02 20:01:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-02","EOSDY":1096,"LSTALVDT":"2024-01-24","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6288,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85843,"AVALU":"g/L","BASE2":2.93854,"BASE":2.88301,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0801,"PCHG2":-2.7259,"CHG":-0.02457,"PCHG":-0.85233,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-27 02:01:15","ADY":967,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-341","SUBJID":"id-341","SITEID":"CAN-1","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.64258,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-20","TRTSDTM":"2019-05-23 08:24:02","TRTEDTM":"2022-02-14 04:53:27","TRT01SDTM":"2019-05-23 08:24:02","TRT01EDTM":"2021-02-13 22:53:27","TRT02SDTM":"2021-02-13 22:53:27","TRT02EDTM":"2022-02-14 04:53:27","AP01SDTM":"2019-05-23 08:24:02","AP01EDTM":"2021-02-13 22:53:27","AP02SDTM":"2021-02-13 22:53:27","AP02EDTM":"2022-02-14 04:53:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":998,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":1013,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7498,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.64582,"AVALU":"U/L","BASE2":21.64582,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-06-13 08:24:02","ADY":21,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-341","SUBJID":"id-341","SITEID":"CAN-1","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.64258,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-20","TRTSDTM":"2019-05-23 08:24:02","TRTEDTM":"2022-02-14 04:53:27","TRT01SDTM":"2019-05-23 08:24:02","TRT01EDTM":"2021-02-13 22:53:27","TRT02SDTM":"2021-02-13 22:53:27","TRT02EDTM":"2022-02-14 04:53:27","AP01SDTM":"2019-05-23 08:24:02","AP01EDTM":"2021-02-13 22:53:27","AP02SDTM":"2021-02-13 22:53:27","AP02EDTM":"2022-02-14 04:53:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":998,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":1013,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":110,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.81454,"AVALU":"U/L","BASE2":21.64582,"BASE":31.81454,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":10.16872,"PCHG2":46.97777,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-26 08:24:02","ADY":430,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-341","SUBJID":"id-341","SITEID":"CAN-1","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.64258,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-20","TRTSDTM":"2019-05-23 08:24:02","TRTEDTM":"2022-02-14 04:53:27","TRT01SDTM":"2019-05-23 08:24:02","TRT01EDTM":"2021-02-13 22:53:27","TRT02SDTM":"2021-02-13 22:53:27","TRT02EDTM":"2022-02-14 04:53:27","AP01SDTM":"2019-05-23 08:24:02","AP01EDTM":"2021-02-13 22:53:27","AP02SDTM":"2021-02-13 22:53:27","AP02EDTM":"2022-02-14 04:53:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":998,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":1013,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1793,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.99729,"AVALU":"U/L","BASE2":21.64582,"BASE":31.81454,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.64853,"PCHG2":-30.71506,"CHG":-16.81725,"PCHG":-52.86026,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-02 08:24:02","ADY":468,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-341","SUBJID":"id-341","SITEID":"CAN-1","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.64258,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-20","TRTSDTM":"2019-05-23 08:24:02","TRTEDTM":"2022-02-14 04:53:27","TRT01SDTM":"2019-05-23 08:24:02","TRT01EDTM":"2021-02-13 22:53:27","TRT02SDTM":"2021-02-13 22:53:27","TRT02EDTM":"2022-02-14 04:53:27","AP01SDTM":"2019-05-23 08:24:02","AP01EDTM":"2021-02-13 22:53:27","AP02SDTM":"2021-02-13 22:53:27","AP02EDTM":"2022-02-14 04:53:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":998,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":1013,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":896,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.70925,"AVALU":"U/L","BASE2":21.64582,"BASE":31.81454,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.06343,"PCHG2":32.63184,"CHG":-3.10529,"PCHG":-9.76061,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-07 08:24:02","ADY":503,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-341","SUBJID":"id-341","SITEID":"CAN-1","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.64258,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-20","TRTSDTM":"2019-05-23 08:24:02","TRTEDTM":"2022-02-14 04:53:27","TRT01SDTM":"2019-05-23 08:24:02","TRT01EDTM":"2021-02-13 22:53:27","TRT02SDTM":"2021-02-13 22:53:27","TRT02EDTM":"2022-02-14 04:53:27","AP01SDTM":"2019-05-23 08:24:02","AP01EDTM":"2021-02-13 22:53:27","AP02SDTM":"2021-02-13 22:53:27","AP02EDTM":"2022-02-14 04:53:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":998,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":1013,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":311,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.86603,"AVALU":"U/L","BASE2":21.64582,"BASE":31.81454,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.22021,"PCHG2":1.01732,"CHG":-9.94852,"PCHG":-31.27034,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-22 08:24:02","ADY":730,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-341","SUBJID":"id-341","SITEID":"CAN-1","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.64258,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-20","TRTSDTM":"2019-05-23 08:24:02","TRTEDTM":"2022-02-14 04:53:27","TRT01SDTM":"2019-05-23 08:24:02","TRT01EDTM":"2021-02-13 22:53:27","TRT02SDTM":"2021-02-13 22:53:27","TRT02EDTM":"2022-02-14 04:53:27","AP01SDTM":"2019-05-23 08:24:02","AP01EDTM":"2021-02-13 22:53:27","AP02SDTM":"2021-02-13 22:53:27","AP02EDTM":"2022-02-14 04:53:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":998,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":1013,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1170,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.09596,"AVALU":"U/L","BASE2":21.64582,"BASE":31.81454,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.54986,"PCHG2":-7.16009,"CHG":-11.71858,"PCHG":-36.83405,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-16 08:24:02","ADY":816,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-341","SUBJID":"id-341","SITEID":"CAN-1","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.64258,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-20","TRTSDTM":"2019-05-23 08:24:02","TRTEDTM":"2022-02-14 04:53:27","TRT01SDTM":"2019-05-23 08:24:02","TRT01EDTM":"2021-02-13 22:53:27","TRT02SDTM":"2021-02-13 22:53:27","TRT02EDTM":"2022-02-14 04:53:27","AP01SDTM":"2019-05-23 08:24:02","AP01EDTM":"2021-02-13 22:53:27","AP02SDTM":"2021-02-13 22:53:27","AP02EDTM":"2022-02-14 04:53:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":998,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":1013,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5007,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.13368,"AVALU":"U/L","BASE2":21.64582,"BASE":31.81454,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.51214,"PCHG2":-53.1841,"CHG":-21.68086,"PCHG":-68.14763,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-08 08:24:02","ADY":992,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-341","SUBJID":"id-341","SITEID":"CAN-1","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.64258,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-20","TRTSDTM":"2019-05-23 08:24:02","TRTEDTM":"2022-02-14 04:53:27","TRT01SDTM":"2019-05-23 08:24:02","TRT01EDTM":"2021-02-13 22:53:27","TRT02SDTM":"2021-02-13 22:53:27","TRT02EDTM":"2022-02-14 04:53:27","AP01SDTM":"2019-05-23 08:24:02","AP01EDTM":"2021-02-13 22:53:27","AP02SDTM":"2021-02-13 22:53:27","AP02EDTM":"2022-02-14 04:53:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":998,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":1013,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2867,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.94536,"AVALU":"mg/L","BASE2":8.94536,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-06-13 08:24:02","ADY":21,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-341","SUBJID":"id-341","SITEID":"CAN-1","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.64258,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-20","TRTSDTM":"2019-05-23 08:24:02","TRTEDTM":"2022-02-14 04:53:27","TRT01SDTM":"2019-05-23 08:24:02","TRT01EDTM":"2021-02-13 22:53:27","TRT02SDTM":"2021-02-13 22:53:27","TRT02EDTM":"2022-02-14 04:53:27","AP01SDTM":"2019-05-23 08:24:02","AP01EDTM":"2021-02-13 22:53:27","AP02SDTM":"2021-02-13 22:53:27","AP02EDTM":"2022-02-14 04:53:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":998,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":1013,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8369,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.59177,"AVALU":"mg/L","BASE2":8.94536,"BASE":8.59177,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.35359,"PCHG2":-3.95281,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-26 08:24:02","ADY":430,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-341","SUBJID":"id-341","SITEID":"CAN-1","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.64258,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-20","TRTSDTM":"2019-05-23 08:24:02","TRTEDTM":"2022-02-14 04:53:27","TRT01SDTM":"2019-05-23 08:24:02","TRT01EDTM":"2021-02-13 22:53:27","TRT02SDTM":"2021-02-13 22:53:27","TRT02EDTM":"2022-02-14 04:53:27","AP01SDTM":"2019-05-23 08:24:02","AP01EDTM":"2021-02-13 22:53:27","AP02SDTM":"2021-02-13 22:53:27","AP02EDTM":"2022-02-14 04:53:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":998,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":1013,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5358,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.14443,"AVALU":"mg/L","BASE2":8.94536,"BASE":8.59177,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.19907,"PCHG2":13.40436,"CHG":1.55266,"PCHG":18.07151,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-09-02 08:24:02","ADY":468,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-341","SUBJID":"id-341","SITEID":"CAN-1","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.64258,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-20","TRTSDTM":"2019-05-23 08:24:02","TRTEDTM":"2022-02-14 04:53:27","TRT01SDTM":"2019-05-23 08:24:02","TRT01EDTM":"2021-02-13 22:53:27","TRT02SDTM":"2021-02-13 22:53:27","TRT02EDTM":"2022-02-14 04:53:27","AP01SDTM":"2019-05-23 08:24:02","AP01EDTM":"2021-02-13 22:53:27","AP02SDTM":"2021-02-13 22:53:27","AP02EDTM":"2022-02-14 04:53:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":998,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":1013,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1130,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.54206,"AVALU":"mg/L","BASE2":8.94536,"BASE":8.59177,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.5967,"PCHG2":6.67049,"CHG":0.95029,"PCHG":11.0605,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-07 08:24:02","ADY":503,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-341","SUBJID":"id-341","SITEID":"CAN-1","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.64258,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-20","TRTSDTM":"2019-05-23 08:24:02","TRTEDTM":"2022-02-14 04:53:27","TRT01SDTM":"2019-05-23 08:24:02","TRT01EDTM":"2021-02-13 22:53:27","TRT02SDTM":"2021-02-13 22:53:27","TRT02EDTM":"2022-02-14 04:53:27","AP01SDTM":"2019-05-23 08:24:02","AP01EDTM":"2021-02-13 22:53:27","AP02SDTM":"2021-02-13 22:53:27","AP02EDTM":"2022-02-14 04:53:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":998,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":1013,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5689,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.4199,"AVALU":"mg/L","BASE2":8.94536,"BASE":8.59177,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.52546,"PCHG2":-17.05305,"CHG":-1.17186,"PCHG":-13.63938,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-05-22 08:24:02","ADY":730,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-341","SUBJID":"id-341","SITEID":"CAN-1","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.64258,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-20","TRTSDTM":"2019-05-23 08:24:02","TRTEDTM":"2022-02-14 04:53:27","TRT01SDTM":"2019-05-23 08:24:02","TRT01EDTM":"2021-02-13 22:53:27","TRT02SDTM":"2021-02-13 22:53:27","TRT02EDTM":"2022-02-14 04:53:27","AP01SDTM":"2019-05-23 08:24:02","AP01EDTM":"2021-02-13 22:53:27","AP02SDTM":"2021-02-13 22:53:27","AP02EDTM":"2022-02-14 04:53:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":998,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":1013,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7203,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.13557,"AVALU":"mg/L","BASE2":8.94536,"BASE":8.59177,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.19021,"PCHG2":13.30529,"CHG":1.5438,"PCHG":17.96835,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-08-16 08:24:02","ADY":816,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-341","SUBJID":"id-341","SITEID":"CAN-1","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.64258,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-20","TRTSDTM":"2019-05-23 08:24:02","TRTEDTM":"2022-02-14 04:53:27","TRT01SDTM":"2019-05-23 08:24:02","TRT01EDTM":"2021-02-13 22:53:27","TRT02SDTM":"2021-02-13 22:53:27","TRT02EDTM":"2022-02-14 04:53:27","AP01SDTM":"2019-05-23 08:24:02","AP01EDTM":"2021-02-13 22:53:27","AP02SDTM":"2021-02-13 22:53:27","AP02EDTM":"2022-02-14 04:53:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":998,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":1013,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6251,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.25718,"AVALU":"mg/L","BASE2":8.94536,"BASE":8.59177,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.31182,"PCHG2":3.48582,"CHG":0.66541,"PCHG":7.74477,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-08 08:24:02","ADY":992,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-341","SUBJID":"id-341","SITEID":"CAN-1","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.64258,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-20","TRTSDTM":"2019-05-23 08:24:02","TRTEDTM":"2022-02-14 04:53:27","TRT01SDTM":"2019-05-23 08:24:02","TRT01EDTM":"2021-02-13 22:53:27","TRT02SDTM":"2021-02-13 22:53:27","TRT02EDTM":"2022-02-14 04:53:27","AP01SDTM":"2019-05-23 08:24:02","AP01EDTM":"2021-02-13 22:53:27","AP02SDTM":"2021-02-13 22:53:27","AP02EDTM":"2022-02-14 04:53:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":998,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":1013,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1715,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87956,"AVALU":"g/L","BASE2":2.87956,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-06-13 08:24:02","ADY":21,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-341","SUBJID":"id-341","SITEID":"CAN-1","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.64258,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-20","TRTSDTM":"2019-05-23 08:24:02","TRTEDTM":"2022-02-14 04:53:27","TRT01SDTM":"2019-05-23 08:24:02","TRT01EDTM":"2021-02-13 22:53:27","TRT02SDTM":"2021-02-13 22:53:27","TRT02EDTM":"2022-02-14 04:53:27","AP01SDTM":"2019-05-23 08:24:02","AP01EDTM":"2021-02-13 22:53:27","AP02SDTM":"2021-02-13 22:53:27","AP02EDTM":"2022-02-14 04:53:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":998,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":1013,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1888,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91132,"AVALU":"g/L","BASE2":2.87956,"BASE":2.91132,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.03175,"PCHG2":1.10269,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-26 08:24:02","ADY":430,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-341","SUBJID":"id-341","SITEID":"CAN-1","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.64258,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-20","TRTSDTM":"2019-05-23 08:24:02","TRTEDTM":"2022-02-14 04:53:27","TRT01SDTM":"2019-05-23 08:24:02","TRT01EDTM":"2021-02-13 22:53:27","TRT02SDTM":"2021-02-13 22:53:27","TRT02EDTM":"2022-02-14 04:53:27","AP01SDTM":"2019-05-23 08:24:02","AP01EDTM":"2021-02-13 22:53:27","AP02SDTM":"2021-02-13 22:53:27","AP02EDTM":"2022-02-14 04:53:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":998,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":1013,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3138,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02073,"AVALU":"g/L","BASE2":2.87956,"BASE":2.91132,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14116,"PCHG2":4.90227,"CHG":0.10941,"PCHG":3.75814,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-09-02 08:24:02","ADY":468,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-341","SUBJID":"id-341","SITEID":"CAN-1","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.64258,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-20","TRTSDTM":"2019-05-23 08:24:02","TRTEDTM":"2022-02-14 04:53:27","TRT01SDTM":"2019-05-23 08:24:02","TRT01EDTM":"2021-02-13 22:53:27","TRT02SDTM":"2021-02-13 22:53:27","TRT02EDTM":"2022-02-14 04:53:27","AP01SDTM":"2019-05-23 08:24:02","AP01EDTM":"2021-02-13 22:53:27","AP02SDTM":"2021-02-13 22:53:27","AP02EDTM":"2022-02-14 04:53:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":998,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":1013,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6344,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78811,"AVALU":"g/L","BASE2":2.87956,"BASE":2.91132,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09145,"PCHG2":-3.1759,"CHG":-0.1232,"PCHG":-4.23193,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-07 08:24:02","ADY":503,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-341","SUBJID":"id-341","SITEID":"CAN-1","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.64258,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-20","TRTSDTM":"2019-05-23 08:24:02","TRTEDTM":"2022-02-14 04:53:27","TRT01SDTM":"2019-05-23 08:24:02","TRT01EDTM":"2021-02-13 22:53:27","TRT02SDTM":"2021-02-13 22:53:27","TRT02EDTM":"2022-02-14 04:53:27","AP01SDTM":"2019-05-23 08:24:02","AP01EDTM":"2021-02-13 22:53:27","AP02SDTM":"2021-02-13 22:53:27","AP02EDTM":"2022-02-14 04:53:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":998,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":1013,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7425,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7475,"AVALU":"g/L","BASE2":2.87956,"BASE":2.91132,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13206,"PCHG2":-4.58613,"CHG":-0.16381,"PCHG":-5.62678,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-22 08:24:02","ADY":730,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-341","SUBJID":"id-341","SITEID":"CAN-1","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.64258,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-20","TRTSDTM":"2019-05-23 08:24:02","TRTEDTM":"2022-02-14 04:53:27","TRT01SDTM":"2019-05-23 08:24:02","TRT01EDTM":"2021-02-13 22:53:27","TRT02SDTM":"2021-02-13 22:53:27","TRT02EDTM":"2022-02-14 04:53:27","AP01SDTM":"2019-05-23 08:24:02","AP01EDTM":"2021-02-13 22:53:27","AP02SDTM":"2021-02-13 22:53:27","AP02EDTM":"2022-02-14 04:53:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":998,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":1013,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2488,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79726,"AVALU":"g/L","BASE2":2.87956,"BASE":2.91132,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08231,"PCHG2":-2.85825,"CHG":-0.11406,"PCHG":-3.91774,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-16 08:24:02","ADY":816,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-1-id-341","SUBJID":"id-341","SITEID":"CAN-1","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-1","INVNAM":"Dr. CAN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":4.64258,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-20","TRTSDTM":"2019-05-23 08:24:02","TRTEDTM":"2022-02-14 04:53:27","TRT01SDTM":"2019-05-23 08:24:02","TRT01EDTM":"2021-02-13 22:53:27","TRT02SDTM":"2021-02-13 22:53:27","TRT02EDTM":"2022-02-14 04:53:27","AP01SDTM":"2019-05-23 08:24:02","AP01EDTM":"2021-02-13 22:53:27","AP02SDTM":"2021-02-13 22:53:27","AP02EDTM":"2022-02-14 04:53:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":998,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":1013,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6118,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97076,"AVALU":"g/L","BASE2":2.87956,"BASE":2.91132,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0912,"PCHG2":3.16704,"CHG":0.05944,"PCHG":2.04184,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-08 08:24:02","ADY":992,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-139","SUBJID":"id-139","SITEID":"CAN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":15.07391,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-14","TRTSDTM":"2020-09-15 01:17:01","TRTEDTM":"2022-02-15 10:49:27","TRT01SDTM":"2020-09-15 01:17:01","TRT01EDTM":"2021-02-15 04:49:27","TRT02SDTM":"2021-02-15 04:49:27","TRT02EDTM":"2022-02-15 10:49:27","AP01SDTM":"2020-09-15 01:17:01","AP01EDTM":"2021-02-15 04:49:27","AP02SDTM":"2021-02-15 04:49:27","AP02EDTM":"2022-02-15 10:49:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":519,"DCSREAS":"DEATH","DTHDT":"2022-04-02","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":46,"LDDTHGR1":">30","LSTALVDT":"2022-04-02","DTHADY":563,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":569,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.64078,"AVALU":"U/L","BASE2":17.64078,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-26 01:17:01","ADY":41,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-139","SUBJID":"id-139","SITEID":"CAN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":15.07391,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-14","TRTSDTM":"2020-09-15 01:17:01","TRTEDTM":"2022-02-15 10:49:27","TRT01SDTM":"2020-09-15 01:17:01","TRT01EDTM":"2021-02-15 04:49:27","TRT02SDTM":"2021-02-15 04:49:27","TRT02EDTM":"2022-02-15 10:49:27","AP01SDTM":"2020-09-15 01:17:01","AP01EDTM":"2021-02-15 04:49:27","AP02SDTM":"2021-02-15 04:49:27","AP02EDTM":"2022-02-15 10:49:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":519,"DCSREAS":"DEATH","DTHDT":"2022-04-02","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":46,"LDDTHGR1":">30","LSTALVDT":"2022-04-02","DTHADY":563,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7442,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.86006,"AVALU":"U/L","BASE2":17.64078,"BASE":17.86006,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.21928,"PCHG2":1.24305,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-04 01:17:01","ADY":50,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-139","SUBJID":"id-139","SITEID":"CAN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":15.07391,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-14","TRTSDTM":"2020-09-15 01:17:01","TRTEDTM":"2022-02-15 10:49:27","TRT01SDTM":"2020-09-15 01:17:01","TRT01EDTM":"2021-02-15 04:49:27","TRT02SDTM":"2021-02-15 04:49:27","TRT02EDTM":"2022-02-15 10:49:27","AP01SDTM":"2020-09-15 01:17:01","AP01EDTM":"2021-02-15 04:49:27","AP02SDTM":"2021-02-15 04:49:27","AP02EDTM":"2022-02-15 10:49:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":519,"DCSREAS":"DEATH","DTHDT":"2022-04-02","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":46,"LDDTHGR1":">30","LSTALVDT":"2022-04-02","DTHADY":563,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3085,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.78419,"AVALU":"U/L","BASE2":17.64078,"BASE":17.86006,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.14342,"PCHG2":40.49378,"CHG":6.92413,"PCHG":38.76881,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-26 01:17:01","ADY":102,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-139","SUBJID":"id-139","SITEID":"CAN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":15.07391,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-14","TRTSDTM":"2020-09-15 01:17:01","TRTEDTM":"2022-02-15 10:49:27","TRT01SDTM":"2020-09-15 01:17:01","TRT01EDTM":"2021-02-15 04:49:27","TRT02SDTM":"2021-02-15 04:49:27","TRT02EDTM":"2022-02-15 10:49:27","AP01SDTM":"2020-09-15 01:17:01","AP01EDTM":"2021-02-15 04:49:27","AP02SDTM":"2021-02-15 04:49:27","AP02EDTM":"2022-02-15 10:49:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":519,"DCSREAS":"DEATH","DTHDT":"2022-04-02","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":46,"LDDTHGR1":">30","LSTALVDT":"2022-04-02","DTHADY":563,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5388,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.04961,"AVALU":"U/L","BASE2":17.64078,"BASE":17.86006,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.59116,"PCHG2":-48.7006,"CHG":-8.81045,"PCHG":-49.33044,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-10 01:17:01","ADY":117,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-139","SUBJID":"id-139","SITEID":"CAN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":15.07391,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-14","TRTSDTM":"2020-09-15 01:17:01","TRTEDTM":"2022-02-15 10:49:27","TRT01SDTM":"2020-09-15 01:17:01","TRT01EDTM":"2021-02-15 04:49:27","TRT02SDTM":"2021-02-15 04:49:27","TRT02EDTM":"2022-02-15 10:49:27","AP01SDTM":"2020-09-15 01:17:01","AP01EDTM":"2021-02-15 04:49:27","AP02SDTM":"2021-02-15 04:49:27","AP02EDTM":"2022-02-15 10:49:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":519,"DCSREAS":"DEATH","DTHDT":"2022-04-02","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":46,"LDDTHGR1":">30","LSTALVDT":"2022-04-02","DTHADY":563,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6363,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.80539,"AVALU":"U/L","BASE2":17.64078,"BASE":17.86006,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.16461,"PCHG2":40.61393,"CHG":6.94533,"PCHG":38.88749,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-31 01:17:01","ADY":138,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-139","SUBJID":"id-139","SITEID":"CAN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":15.07391,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-14","TRTSDTM":"2020-09-15 01:17:01","TRTEDTM":"2022-02-15 10:49:27","TRT01SDTM":"2020-09-15 01:17:01","TRT01EDTM":"2021-02-15 04:49:27","TRT02SDTM":"2021-02-15 04:49:27","TRT02EDTM":"2022-02-15 10:49:27","AP01SDTM":"2020-09-15 01:17:01","AP01EDTM":"2021-02-15 04:49:27","AP02SDTM":"2021-02-15 04:49:27","AP02EDTM":"2022-02-15 10:49:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":519,"DCSREAS":"DEATH","DTHDT":"2022-04-02","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":46,"LDDTHGR1":">30","LSTALVDT":"2022-04-02","DTHADY":563,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5101,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.13486,"AVALU":"U/L","BASE2":17.64078,"BASE":17.86006,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.49408,"PCHG2":19.80686,"CHG":3.2748,"PCHG":18.33589,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-11 01:17:01","ADY":238,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-139","SUBJID":"id-139","SITEID":"CAN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":15.07391,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-14","TRTSDTM":"2020-09-15 01:17:01","TRTEDTM":"2022-02-15 10:49:27","TRT01SDTM":"2020-09-15 01:17:01","TRT01EDTM":"2021-02-15 04:49:27","TRT02SDTM":"2021-02-15 04:49:27","TRT02EDTM":"2022-02-15 10:49:27","AP01SDTM":"2020-09-15 01:17:01","AP01EDTM":"2021-02-15 04:49:27","AP02SDTM":"2021-02-15 04:49:27","AP02EDTM":"2022-02-15 10:49:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":519,"DCSREAS":"DEATH","DTHDT":"2022-04-02","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":46,"LDDTHGR1":">30","LSTALVDT":"2022-04-02","DTHADY":563,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":126,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.52147,"AVALU":"U/L","BASE2":17.64078,"BASE":17.86006,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.88069,"PCHG2":56.01052,"CHG":9.66141,"PCHG":54.09505,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-27 01:17:01","ADY":499,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-139","SUBJID":"id-139","SITEID":"CAN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":15.07391,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-14","TRTSDTM":"2020-09-15 01:17:01","TRTEDTM":"2022-02-15 10:49:27","TRT01SDTM":"2020-09-15 01:17:01","TRT01EDTM":"2021-02-15 04:49:27","TRT02SDTM":"2021-02-15 04:49:27","TRT02EDTM":"2022-02-15 10:49:27","AP01SDTM":"2020-09-15 01:17:01","AP01EDTM":"2021-02-15 04:49:27","AP02SDTM":"2021-02-15 04:49:27","AP02EDTM":"2022-02-15 10:49:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":519,"DCSREAS":"DEATH","DTHDT":"2022-04-02","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":46,"LDDTHGR1":">30","LSTALVDT":"2022-04-02","DTHADY":563,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6985,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.14166,"AVALU":"mg/L","BASE2":8.14166,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-10-26 01:17:01","ADY":41,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-139","SUBJID":"id-139","SITEID":"CAN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":15.07391,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-14","TRTSDTM":"2020-09-15 01:17:01","TRTEDTM":"2022-02-15 10:49:27","TRT01SDTM":"2020-09-15 01:17:01","TRT01EDTM":"2021-02-15 04:49:27","TRT02SDTM":"2021-02-15 04:49:27","TRT02EDTM":"2022-02-15 10:49:27","AP01SDTM":"2020-09-15 01:17:01","AP01EDTM":"2021-02-15 04:49:27","AP02SDTM":"2021-02-15 04:49:27","AP02EDTM":"2022-02-15 10:49:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":519,"DCSREAS":"DEATH","DTHDT":"2022-04-02","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":46,"LDDTHGR1":">30","LSTALVDT":"2022-04-02","DTHADY":563,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1739,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.01894,"AVALU":"mg/L","BASE2":8.14166,"BASE":10.01894,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.87729,"PCHG2":23.0578,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-11-04 01:17:01","ADY":50,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-139","SUBJID":"id-139","SITEID":"CAN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":15.07391,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-14","TRTSDTM":"2020-09-15 01:17:01","TRTEDTM":"2022-02-15 10:49:27","TRT01SDTM":"2020-09-15 01:17:01","TRT01EDTM":"2021-02-15 04:49:27","TRT02SDTM":"2021-02-15 04:49:27","TRT02EDTM":"2022-02-15 10:49:27","AP01SDTM":"2020-09-15 01:17:01","AP01EDTM":"2021-02-15 04:49:27","AP02SDTM":"2021-02-15 04:49:27","AP02EDTM":"2022-02-15 10:49:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":519,"DCSREAS":"DEATH","DTHDT":"2022-04-02","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":46,"LDDTHGR1":">30","LSTALVDT":"2022-04-02","DTHADY":563,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2241,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.55863,"AVALU":"mg/L","BASE2":8.14166,"BASE":10.01894,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.41697,"PCHG2":5.12146,"CHG":-1.46032,"PCHG":-14.57554,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-12-26 01:17:01","ADY":102,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-139","SUBJID":"id-139","SITEID":"CAN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":15.07391,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-14","TRTSDTM":"2020-09-15 01:17:01","TRTEDTM":"2022-02-15 10:49:27","TRT01SDTM":"2020-09-15 01:17:01","TRT01EDTM":"2021-02-15 04:49:27","TRT02SDTM":"2021-02-15 04:49:27","TRT02EDTM":"2022-02-15 10:49:27","AP01SDTM":"2020-09-15 01:17:01","AP01EDTM":"2021-02-15 04:49:27","AP02SDTM":"2021-02-15 04:49:27","AP02EDTM":"2022-02-15 10:49:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":519,"DCSREAS":"DEATH","DTHDT":"2022-04-02","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":46,"LDDTHGR1":">30","LSTALVDT":"2022-04-02","DTHADY":563,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5027,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.94015,"AVALU":"mg/L","BASE2":8.14166,"BASE":10.01894,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.7985,"PCHG2":22.09008,"CHG":-0.07879,"PCHG":-0.78639,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-01-10 01:17:01","ADY":117,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-139","SUBJID":"id-139","SITEID":"CAN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":15.07391,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-14","TRTSDTM":"2020-09-15 01:17:01","TRTEDTM":"2022-02-15 10:49:27","TRT01SDTM":"2020-09-15 01:17:01","TRT01EDTM":"2021-02-15 04:49:27","TRT02SDTM":"2021-02-15 04:49:27","TRT02EDTM":"2022-02-15 10:49:27","AP01SDTM":"2020-09-15 01:17:01","AP01EDTM":"2021-02-15 04:49:27","AP02SDTM":"2021-02-15 04:49:27","AP02EDTM":"2022-02-15 10:49:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":519,"DCSREAS":"DEATH","DTHDT":"2022-04-02","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":46,"LDDTHGR1":">30","LSTALVDT":"2022-04-02","DTHADY":563,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3451,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.78411,"AVALU":"mg/L","BASE2":8.14166,"BASE":10.01894,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.35755,"PCHG2":-4.39156,"CHG":-2.23483,"PCHG":-22.30607,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-4","BTOXGR":"1","ADTM":"2021-01-31 01:17:01","ADY":138,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-139","SUBJID":"id-139","SITEID":"CAN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":15.07391,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-14","TRTSDTM":"2020-09-15 01:17:01","TRTEDTM":"2022-02-15 10:49:27","TRT01SDTM":"2020-09-15 01:17:01","TRT01EDTM":"2021-02-15 04:49:27","TRT02SDTM":"2021-02-15 04:49:27","TRT02EDTM":"2022-02-15 10:49:27","AP01SDTM":"2020-09-15 01:17:01","AP01EDTM":"2021-02-15 04:49:27","AP02SDTM":"2021-02-15 04:49:27","AP02EDTM":"2022-02-15 10:49:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":519,"DCSREAS":"DEATH","DTHDT":"2022-04-02","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":46,"LDDTHGR1":">30","LSTALVDT":"2022-04-02","DTHADY":563,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3983,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.52846,"AVALU":"mg/L","BASE2":8.14166,"BASE":10.01894,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.3868,"PCHG2":4.75092,"CHG":-1.49048,"PCHG":-14.87665,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-05-11 01:17:01","ADY":238,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-139","SUBJID":"id-139","SITEID":"CAN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":15.07391,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-14","TRTSDTM":"2020-09-15 01:17:01","TRTEDTM":"2022-02-15 10:49:27","TRT01SDTM":"2020-09-15 01:17:01","TRT01EDTM":"2021-02-15 04:49:27","TRT02SDTM":"2021-02-15 04:49:27","TRT02EDTM":"2022-02-15 10:49:27","AP01SDTM":"2020-09-15 01:17:01","AP01EDTM":"2021-02-15 04:49:27","AP02SDTM":"2021-02-15 04:49:27","AP02EDTM":"2022-02-15 10:49:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":519,"DCSREAS":"DEATH","DTHDT":"2022-04-02","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":46,"LDDTHGR1":">30","LSTALVDT":"2022-04-02","DTHADY":563,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":194,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.06107,"AVALU":"mg/L","BASE2":8.14166,"BASE":10.01894,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.91941,"PCHG2":23.57522,"CHG":0.04213,"PCHG":0.42047,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"4","BTOXGR":"1","ADTM":"2022-01-27 01:17:01","ADY":499,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-139","SUBJID":"id-139","SITEID":"CAN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":15.07391,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-14","TRTSDTM":"2020-09-15 01:17:01","TRTEDTM":"2022-02-15 10:49:27","TRT01SDTM":"2020-09-15 01:17:01","TRT01EDTM":"2021-02-15 04:49:27","TRT02SDTM":"2021-02-15 04:49:27","TRT02EDTM":"2022-02-15 10:49:27","AP01SDTM":"2020-09-15 01:17:01","AP01EDTM":"2021-02-15 04:49:27","AP02SDTM":"2021-02-15 04:49:27","AP02EDTM":"2022-02-15 10:49:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":519,"DCSREAS":"DEATH","DTHDT":"2022-04-02","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":46,"LDDTHGR1":">30","LSTALVDT":"2022-04-02","DTHADY":563,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7258,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.12734,"AVALU":"g/L","BASE2":3.12734,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"1","ADTM":"2020-10-26 01:17:01","ADY":41,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-139","SUBJID":"id-139","SITEID":"CAN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":15.07391,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-14","TRTSDTM":"2020-09-15 01:17:01","TRTEDTM":"2022-02-15 10:49:27","TRT01SDTM":"2020-09-15 01:17:01","TRT01EDTM":"2021-02-15 04:49:27","TRT02SDTM":"2021-02-15 04:49:27","TRT02EDTM":"2022-02-15 10:49:27","AP01SDTM":"2020-09-15 01:17:01","AP01EDTM":"2021-02-15 04:49:27","AP02SDTM":"2021-02-15 04:49:27","AP02EDTM":"2022-02-15 10:49:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":519,"DCSREAS":"DEATH","DTHDT":"2022-04-02","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":46,"LDDTHGR1":">30","LSTALVDT":"2022-04-02","DTHADY":563,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6410,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.12164,"AVALU":"g/L","BASE2":3.12734,"BASE":3.12164,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.0057,"PCHG2":-0.18232,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-11-04 01:17:01","ADY":50,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-139","SUBJID":"id-139","SITEID":"CAN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":15.07391,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-14","TRTSDTM":"2020-09-15 01:17:01","TRTEDTM":"2022-02-15 10:49:27","TRT01SDTM":"2020-09-15 01:17:01","TRT01EDTM":"2021-02-15 04:49:27","TRT02SDTM":"2021-02-15 04:49:27","TRT02EDTM":"2022-02-15 10:49:27","AP01SDTM":"2020-09-15 01:17:01","AP01EDTM":"2021-02-15 04:49:27","AP02SDTM":"2021-02-15 04:49:27","AP02EDTM":"2022-02-15 10:49:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":519,"DCSREAS":"DEATH","DTHDT":"2022-04-02","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":46,"LDDTHGR1":">30","LSTALVDT":"2022-04-02","DTHADY":563,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5634,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88202,"AVALU":"g/L","BASE2":3.12734,"BASE":3.12164,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.24532,"PCHG2":-7.84424,"CHG":-0.23961,"PCHG":-7.67592,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-12-26 01:17:01","ADY":102,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-139","SUBJID":"id-139","SITEID":"CAN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":15.07391,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-14","TRTSDTM":"2020-09-15 01:17:01","TRTEDTM":"2022-02-15 10:49:27","TRT01SDTM":"2020-09-15 01:17:01","TRT01EDTM":"2021-02-15 04:49:27","TRT02SDTM":"2021-02-15 04:49:27","TRT02EDTM":"2022-02-15 10:49:27","AP01SDTM":"2020-09-15 01:17:01","AP01EDTM":"2021-02-15 04:49:27","AP02SDTM":"2021-02-15 04:49:27","AP02EDTM":"2022-02-15 10:49:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":519,"DCSREAS":"DEATH","DTHDT":"2022-04-02","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":46,"LDDTHGR1":">30","LSTALVDT":"2022-04-02","DTHADY":563,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6586,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91842,"AVALU":"g/L","BASE2":3.12734,"BASE":3.12164,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20892,"PCHG2":-6.68041,"CHG":-0.20322,"PCHG":-6.50996,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-01-10 01:17:01","ADY":117,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-139","SUBJID":"id-139","SITEID":"CAN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":15.07391,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-14","TRTSDTM":"2020-09-15 01:17:01","TRTEDTM":"2022-02-15 10:49:27","TRT01SDTM":"2020-09-15 01:17:01","TRT01EDTM":"2021-02-15 04:49:27","TRT02SDTM":"2021-02-15 04:49:27","TRT02EDTM":"2022-02-15 10:49:27","AP01SDTM":"2020-09-15 01:17:01","AP01EDTM":"2021-02-15 04:49:27","AP02SDTM":"2021-02-15 04:49:27","AP02EDTM":"2022-02-15 10:49:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":519,"DCSREAS":"DEATH","DTHDT":"2022-04-02","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":46,"LDDTHGR1":">30","LSTALVDT":"2022-04-02","DTHADY":563,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5672,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91413,"AVALU":"g/L","BASE2":3.12734,"BASE":3.12164,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21321,"PCHG2":-6.81759,"CHG":-0.20751,"PCHG":-6.64739,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-01-31 01:17:01","ADY":138,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-139","SUBJID":"id-139","SITEID":"CAN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":15.07391,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-14","TRTSDTM":"2020-09-15 01:17:01","TRTEDTM":"2022-02-15 10:49:27","TRT01SDTM":"2020-09-15 01:17:01","TRT01EDTM":"2021-02-15 04:49:27","TRT02SDTM":"2021-02-15 04:49:27","TRT02EDTM":"2022-02-15 10:49:27","AP01SDTM":"2020-09-15 01:17:01","AP01EDTM":"2021-02-15 04:49:27","AP02SDTM":"2021-02-15 04:49:27","AP02EDTM":"2022-02-15 10:49:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":519,"DCSREAS":"DEATH","DTHDT":"2022-04-02","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":46,"LDDTHGR1":">30","LSTALVDT":"2022-04-02","DTHADY":563,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":978,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95042,"AVALU":"g/L","BASE2":3.12734,"BASE":3.12164,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17692,"PCHG2":-5.65729,"CHG":-0.17122,"PCHG":-5.48497,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-05-11 01:17:01","ADY":238,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-139","SUBJID":"id-139","SITEID":"CAN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"Y","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":15.07391,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-14","TRTSDTM":"2020-09-15 01:17:01","TRTEDTM":"2022-02-15 10:49:27","TRT01SDTM":"2020-09-15 01:17:01","TRT01EDTM":"2021-02-15 04:49:27","TRT02SDTM":"2021-02-15 04:49:27","TRT02EDTM":"2022-02-15 10:49:27","AP01SDTM":"2020-09-15 01:17:01","AP01EDTM":"2021-02-15 04:49:27","AP02SDTM":"2021-02-15 04:49:27","AP02EDTM":"2022-02-15 10:49:27","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":519,"DCSREAS":"DEATH","DTHDT":"2022-04-02","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":46,"LDDTHGR1":">30","LSTALVDT":"2022-04-02","DTHADY":563,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8149,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97069,"AVALU":"g/L","BASE2":3.12734,"BASE":3.12164,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15665,"PCHG2":-5.00893,"CHG":-0.15094,"PCHG":-4.83543,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2022-01-27 01:17:01","ADY":499,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-306","SUBJID":"id-306","SITEID":"CAN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.11267,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-04","TRTSDTM":"2020-06-08 23:55:30","TRTEDTM":"2023-06-09 17:55:30","TRT01SDTM":"2020-06-08 23:55:30","TRT01EDTM":"2022-06-09 11:55:30","TRT02SDTM":"2022-06-09 11:55:30","TRT02EDTM":"2023-06-09 17:55:30","AP01SDTM":"2020-06-08 23:55:30","AP01EDTM":"2022-06-09 11:55:30","AP02SDTM":"2022-06-09 11:55:30","AP02EDTM":"2023-06-09 17:55:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-09","EOSDY":1096,"LSTALVDT":"2023-07-05","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5279,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.77816,"AVALU":"U/L","BASE2":13.77816,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-24 23:55:30","ADY":626,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-306","SUBJID":"id-306","SITEID":"CAN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.11267,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-04","TRTSDTM":"2020-06-08 23:55:30","TRTEDTM":"2023-06-09 17:55:30","TRT01SDTM":"2020-06-08 23:55:30","TRT01EDTM":"2022-06-09 11:55:30","TRT02SDTM":"2022-06-09 11:55:30","TRT02EDTM":"2023-06-09 17:55:30","AP01SDTM":"2020-06-08 23:55:30","AP01EDTM":"2022-06-09 11:55:30","AP02SDTM":"2022-06-09 11:55:30","AP02EDTM":"2023-06-09 17:55:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-09","EOSDY":1096,"LSTALVDT":"2023-07-05","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2654,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.72747,"AVALU":"U/L","BASE2":13.77816,"BASE":9.72747,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-4.05069,"PCHG2":-29.39936,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-01 23:55:30","ADY":723,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-306","SUBJID":"id-306","SITEID":"CAN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.11267,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-04","TRTSDTM":"2020-06-08 23:55:30","TRTEDTM":"2023-06-09 17:55:30","TRT01SDTM":"2020-06-08 23:55:30","TRT01EDTM":"2022-06-09 11:55:30","TRT02SDTM":"2022-06-09 11:55:30","TRT02EDTM":"2023-06-09 17:55:30","AP01SDTM":"2020-06-08 23:55:30","AP01EDTM":"2022-06-09 11:55:30","AP02SDTM":"2022-06-09 11:55:30","AP02EDTM":"2023-06-09 17:55:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-09","EOSDY":1096,"LSTALVDT":"2023-07-05","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":725,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.88491,"AVALU":"U/L","BASE2":13.77816,"BASE":9.72747,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.10675,"PCHG2":22.54838,"CHG":7.15744,"PCHG":73.57969,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-07 23:55:30","ADY":729,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-306","SUBJID":"id-306","SITEID":"CAN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.11267,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-04","TRTSDTM":"2020-06-08 23:55:30","TRTEDTM":"2023-06-09 17:55:30","TRT01SDTM":"2020-06-08 23:55:30","TRT01EDTM":"2022-06-09 11:55:30","TRT02SDTM":"2022-06-09 11:55:30","TRT02EDTM":"2023-06-09 17:55:30","AP01SDTM":"2020-06-08 23:55:30","AP01EDTM":"2022-06-09 11:55:30","AP02SDTM":"2022-06-09 11:55:30","AP02EDTM":"2023-06-09 17:55:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-09","EOSDY":1096,"LSTALVDT":"2023-07-05","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3931,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.33498,"AVALU":"U/L","BASE2":13.77816,"BASE":9.72747,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.55682,"PCHG2":47.58848,"CHG":10.60751,"PCHG":109.04693,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-31 23:55:30","ADY":875,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-306","SUBJID":"id-306","SITEID":"CAN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.11267,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-04","TRTSDTM":"2020-06-08 23:55:30","TRTEDTM":"2023-06-09 17:55:30","TRT01SDTM":"2020-06-08 23:55:30","TRT01EDTM":"2022-06-09 11:55:30","TRT02SDTM":"2022-06-09 11:55:30","TRT02EDTM":"2023-06-09 17:55:30","AP01SDTM":"2020-06-08 23:55:30","AP01EDTM":"2022-06-09 11:55:30","AP02SDTM":"2022-06-09 11:55:30","AP02EDTM":"2023-06-09 17:55:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-09","EOSDY":1096,"LSTALVDT":"2023-07-05","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7716,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.66387,"AVALU":"U/L","BASE2":13.77816,"BASE":9.72747,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.88571,"PCHG2":108.03844,"CHG":18.9364,"PCHG":194.66932,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-05 23:55:30","ADY":972,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-306","SUBJID":"id-306","SITEID":"CAN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.11267,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-04","TRTSDTM":"2020-06-08 23:55:30","TRTEDTM":"2023-06-09 17:55:30","TRT01SDTM":"2020-06-08 23:55:30","TRT01EDTM":"2022-06-09 11:55:30","TRT02SDTM":"2022-06-09 11:55:30","TRT02EDTM":"2023-06-09 17:55:30","AP01SDTM":"2020-06-08 23:55:30","AP01EDTM":"2022-06-09 11:55:30","AP02SDTM":"2022-06-09 11:55:30","AP02EDTM":"2023-06-09 17:55:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-09","EOSDY":1096,"LSTALVDT":"2023-07-05","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4606,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.65649,"AVALU":"U/L","BASE2":13.77816,"BASE":9.72747,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.87833,"PCHG2":78.95343,"CHG":14.92902,"PCHG":153.47281,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-10 23:55:30","ADY":977,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-306","SUBJID":"id-306","SITEID":"CAN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.11267,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-04","TRTSDTM":"2020-06-08 23:55:30","TRTEDTM":"2023-06-09 17:55:30","TRT01SDTM":"2020-06-08 23:55:30","TRT01EDTM":"2022-06-09 11:55:30","TRT02SDTM":"2022-06-09 11:55:30","TRT02EDTM":"2023-06-09 17:55:30","AP01SDTM":"2020-06-08 23:55:30","AP01EDTM":"2022-06-09 11:55:30","AP02SDTM":"2022-06-09 11:55:30","AP02EDTM":"2023-06-09 17:55:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-09","EOSDY":1096,"LSTALVDT":"2023-07-05","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":287,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.29657,"AVALU":"U/L","BASE2":13.77816,"BASE":9.72747,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.51841,"PCHG2":47.3097,"CHG":10.5691,"PCHG":108.65206,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-21 23:55:30","ADY":1047,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-306","SUBJID":"id-306","SITEID":"CAN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.11267,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-04","TRTSDTM":"2020-06-08 23:55:30","TRTEDTM":"2023-06-09 17:55:30","TRT01SDTM":"2020-06-08 23:55:30","TRT01EDTM":"2022-06-09 11:55:30","TRT02SDTM":"2022-06-09 11:55:30","TRT02EDTM":"2023-06-09 17:55:30","AP01SDTM":"2020-06-08 23:55:30","AP01EDTM":"2022-06-09 11:55:30","AP02SDTM":"2022-06-09 11:55:30","AP02EDTM":"2023-06-09 17:55:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-09","EOSDY":1096,"LSTALVDT":"2023-07-05","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3120,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.36353,"AVALU":"mg/L","BASE2":9.36353,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-02-24 23:55:30","ADY":626,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-306","SUBJID":"id-306","SITEID":"CAN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.11267,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-04","TRTSDTM":"2020-06-08 23:55:30","TRTEDTM":"2023-06-09 17:55:30","TRT01SDTM":"2020-06-08 23:55:30","TRT01EDTM":"2022-06-09 11:55:30","TRT02SDTM":"2022-06-09 11:55:30","TRT02EDTM":"2023-06-09 17:55:30","AP01SDTM":"2020-06-08 23:55:30","AP01EDTM":"2022-06-09 11:55:30","AP02SDTM":"2022-06-09 11:55:30","AP02EDTM":"2023-06-09 17:55:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-09","EOSDY":1096,"LSTALVDT":"2023-07-05","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4753,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.51633,"AVALU":"mg/L","BASE2":9.36353,"BASE":7.51633,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.84721,"PCHG2":-19.72768,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2022-06-01 23:55:30","ADY":723,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-306","SUBJID":"id-306","SITEID":"CAN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.11267,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-04","TRTSDTM":"2020-06-08 23:55:30","TRTEDTM":"2023-06-09 17:55:30","TRT01SDTM":"2020-06-08 23:55:30","TRT01EDTM":"2022-06-09 11:55:30","TRT02SDTM":"2022-06-09 11:55:30","TRT02EDTM":"2023-06-09 17:55:30","AP01SDTM":"2020-06-08 23:55:30","AP01EDTM":"2022-06-09 11:55:30","AP02SDTM":"2022-06-09 11:55:30","AP02EDTM":"2023-06-09 17:55:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-09","EOSDY":1096,"LSTALVDT":"2023-07-05","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2773,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.02938,"AVALU":"mg/L","BASE2":9.36353,"BASE":7.51633,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.33415,"PCHG2":-3.56863,"CHG":1.51306,"PCHG":20.13029,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-06-07 23:55:30","ADY":729,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-306","SUBJID":"id-306","SITEID":"CAN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.11267,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-04","TRTSDTM":"2020-06-08 23:55:30","TRTEDTM":"2023-06-09 17:55:30","TRT01SDTM":"2020-06-08 23:55:30","TRT01EDTM":"2022-06-09 11:55:30","TRT02SDTM":"2022-06-09 11:55:30","TRT02EDTM":"2023-06-09 17:55:30","AP01SDTM":"2020-06-08 23:55:30","AP01EDTM":"2022-06-09 11:55:30","AP02SDTM":"2022-06-09 11:55:30","AP02EDTM":"2023-06-09 17:55:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-09","EOSDY":1096,"LSTALVDT":"2023-07-05","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6368,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.53358,"AVALU":"mg/L","BASE2":9.36353,"BASE":7.51633,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.17004,"PCHG2":12.49575,"CHG":3.01725,"PCHG":40.14264,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"1","BTOXGR":"-1","ADTM":"2022-10-31 23:55:30","ADY":875,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-306","SUBJID":"id-306","SITEID":"CAN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.11267,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-04","TRTSDTM":"2020-06-08 23:55:30","TRTEDTM":"2023-06-09 17:55:30","TRT01SDTM":"2020-06-08 23:55:30","TRT01EDTM":"2022-06-09 11:55:30","TRT02SDTM":"2022-06-09 11:55:30","TRT02EDTM":"2023-06-09 17:55:30","AP01SDTM":"2020-06-08 23:55:30","AP01EDTM":"2022-06-09 11:55:30","AP02SDTM":"2022-06-09 11:55:30","AP02EDTM":"2023-06-09 17:55:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-09","EOSDY":1096,"LSTALVDT":"2023-07-05","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":863,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.44507,"AVALU":"mg/L","BASE2":9.36353,"BASE":7.51633,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.91846,"PCHG2":-9.80892,"CHG":0.92875,"PCHG":12.35638,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2023-02-05 23:55:30","ADY":972,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-306","SUBJID":"id-306","SITEID":"CAN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.11267,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-04","TRTSDTM":"2020-06-08 23:55:30","TRTEDTM":"2023-06-09 17:55:30","TRT01SDTM":"2020-06-08 23:55:30","TRT01EDTM":"2022-06-09 11:55:30","TRT02SDTM":"2022-06-09 11:55:30","TRT02EDTM":"2023-06-09 17:55:30","AP01SDTM":"2020-06-08 23:55:30","AP01EDTM":"2022-06-09 11:55:30","AP02SDTM":"2022-06-09 11:55:30","AP02EDTM":"2023-06-09 17:55:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-09","EOSDY":1096,"LSTALVDT":"2023-07-05","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1430,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.73452,"AVALU":"mg/L","BASE2":9.36353,"BASE":7.51633,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.37099,"PCHG2":14.64175,"CHG":3.21819,"PCHG":42.81604,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"1","BTOXGR":"-1","ADTM":"2023-02-10 23:55:30","ADY":977,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-306","SUBJID":"id-306","SITEID":"CAN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.11267,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-04","TRTSDTM":"2020-06-08 23:55:30","TRTEDTM":"2023-06-09 17:55:30","TRT01SDTM":"2020-06-08 23:55:30","TRT01EDTM":"2022-06-09 11:55:30","TRT02SDTM":"2022-06-09 11:55:30","TRT02EDTM":"2023-06-09 17:55:30","AP01SDTM":"2020-06-08 23:55:30","AP01EDTM":"2022-06-09 11:55:30","AP02SDTM":"2022-06-09 11:55:30","AP02EDTM":"2023-06-09 17:55:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-09","EOSDY":1096,"LSTALVDT":"2023-07-05","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8210,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.7214,"AVALU":"mg/L","BASE2":9.36353,"BASE":7.51633,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.64213,"PCHG2":-17.5375,"CHG":0.20508,"PCHG":2.72844,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-4","BTOXGR":"-1","ADTM":"2023-04-21 23:55:30","ADY":1047,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-306","SUBJID":"id-306","SITEID":"CAN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.11267,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-04","TRTSDTM":"2020-06-08 23:55:30","TRTEDTM":"2023-06-09 17:55:30","TRT01SDTM":"2020-06-08 23:55:30","TRT01EDTM":"2022-06-09 11:55:30","TRT02SDTM":"2022-06-09 11:55:30","TRT02EDTM":"2023-06-09 17:55:30","AP01SDTM":"2020-06-08 23:55:30","AP01EDTM":"2022-06-09 11:55:30","AP02SDTM":"2022-06-09 11:55:30","AP02EDTM":"2023-06-09 17:55:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-09","EOSDY":1096,"LSTALVDT":"2023-07-05","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6164,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75648,"AVALU":"g/L","BASE2":2.75648,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-24 23:55:30","ADY":626,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-306","SUBJID":"id-306","SITEID":"CAN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.11267,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-04","TRTSDTM":"2020-06-08 23:55:30","TRTEDTM":"2023-06-09 17:55:30","TRT01SDTM":"2020-06-08 23:55:30","TRT01EDTM":"2022-06-09 11:55:30","TRT02SDTM":"2022-06-09 11:55:30","TRT02EDTM":"2023-06-09 17:55:30","AP01SDTM":"2020-06-08 23:55:30","AP01EDTM":"2022-06-09 11:55:30","AP02SDTM":"2022-06-09 11:55:30","AP02EDTM":"2023-06-09 17:55:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-09","EOSDY":1096,"LSTALVDT":"2023-07-05","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6136,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93374,"AVALU":"g/L","BASE2":2.75648,"BASE":2.93374,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.17727,"PCHG2":6.43087,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-01 23:55:30","ADY":723,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-306","SUBJID":"id-306","SITEID":"CAN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.11267,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-04","TRTSDTM":"2020-06-08 23:55:30","TRTEDTM":"2023-06-09 17:55:30","TRT01SDTM":"2020-06-08 23:55:30","TRT01EDTM":"2022-06-09 11:55:30","TRT02SDTM":"2022-06-09 11:55:30","TRT02EDTM":"2023-06-09 17:55:30","AP01SDTM":"2020-06-08 23:55:30","AP01EDTM":"2022-06-09 11:55:30","AP02SDTM":"2022-06-09 11:55:30","AP02EDTM":"2023-06-09 17:55:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-09","EOSDY":1096,"LSTALVDT":"2023-07-05","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5878,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91935,"AVALU":"g/L","BASE2":2.75648,"BASE":2.93374,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16287,"PCHG2":5.90854,"CHG":-0.0144,"PCHG":-0.49077,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-07 23:55:30","ADY":729,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-306","SUBJID":"id-306","SITEID":"CAN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.11267,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-04","TRTSDTM":"2020-06-08 23:55:30","TRTEDTM":"2023-06-09 17:55:30","TRT01SDTM":"2020-06-08 23:55:30","TRT01EDTM":"2022-06-09 11:55:30","TRT02SDTM":"2022-06-09 11:55:30","TRT02EDTM":"2023-06-09 17:55:30","AP01SDTM":"2020-06-08 23:55:30","AP01EDTM":"2022-06-09 11:55:30","AP02SDTM":"2022-06-09 11:55:30","AP02EDTM":"2023-06-09 17:55:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-09","EOSDY":1096,"LSTALVDT":"2023-07-05","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5054,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83915,"AVALU":"g/L","BASE2":2.75648,"BASE":2.93374,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08267,"PCHG2":2.99909,"CHG":-0.0946,"PCHG":-3.22442,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-31 23:55:30","ADY":875,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-306","SUBJID":"id-306","SITEID":"CAN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.11267,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-04","TRTSDTM":"2020-06-08 23:55:30","TRTEDTM":"2023-06-09 17:55:30","TRT01SDTM":"2020-06-08 23:55:30","TRT01EDTM":"2022-06-09 11:55:30","TRT02SDTM":"2022-06-09 11:55:30","TRT02EDTM":"2023-06-09 17:55:30","AP01SDTM":"2020-06-08 23:55:30","AP01EDTM":"2022-06-09 11:55:30","AP02SDTM":"2022-06-09 11:55:30","AP02EDTM":"2023-06-09 17:55:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-09","EOSDY":1096,"LSTALVDT":"2023-07-05","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6535,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88348,"AVALU":"g/L","BASE2":2.75648,"BASE":2.93374,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.127,"PCHG2":4.60738,"CHG":-0.05026,"PCHG":-1.71331,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-05 23:55:30","ADY":972,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-306","SUBJID":"id-306","SITEID":"CAN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.11267,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-04","TRTSDTM":"2020-06-08 23:55:30","TRTEDTM":"2023-06-09 17:55:30","TRT01SDTM":"2020-06-08 23:55:30","TRT01EDTM":"2022-06-09 11:55:30","TRT02SDTM":"2022-06-09 11:55:30","TRT02EDTM":"2023-06-09 17:55:30","AP01SDTM":"2020-06-08 23:55:30","AP01EDTM":"2022-06-09 11:55:30","AP02SDTM":"2022-06-09 11:55:30","AP02EDTM":"2023-06-09 17:55:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-09","EOSDY":1096,"LSTALVDT":"2023-07-05","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8196,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91709,"AVALU":"g/L","BASE2":2.75648,"BASE":2.93374,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16061,"PCHG2":5.82678,"CHG":-0.01665,"PCHG":-0.56759,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-10 23:55:30","ADY":977,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-11-id-306","SUBJID":"id-306","SITEID":"CAN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-11","INVNAM":"Dr. CAN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":3.11267,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-04","TRTSDTM":"2020-06-08 23:55:30","TRTEDTM":"2023-06-09 17:55:30","TRT01SDTM":"2020-06-08 23:55:30","TRT01EDTM":"2022-06-09 11:55:30","TRT02SDTM":"2022-06-09 11:55:30","TRT02EDTM":"2023-06-09 17:55:30","AP01SDTM":"2020-06-08 23:55:30","AP01EDTM":"2022-06-09 11:55:30","AP02SDTM":"2022-06-09 11:55:30","AP02EDTM":"2023-06-09 17:55:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-09","EOSDY":1096,"LSTALVDT":"2023-07-05","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5686,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00679,"AVALU":"g/L","BASE2":2.75648,"BASE":2.93374,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.25031,"PCHG2":9.08088,"CHG":0.07305,"PCHG":2.48989,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2023-04-21 23:55:30","ADY":1047,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-14-id-104","SUBJID":"id-104","SITEID":"CAN-14","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-14","INVNAM":"Dr. CAN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.66313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-26","TRTSDTM":"2019-06-28 02:51:57","TRTEDTM":"2022-06-27 20:51:57","TRT01SDTM":"2019-06-28 02:51:57","TRT01EDTM":"2021-06-27 14:51:57","TRT02SDTM":"2021-06-27 14:51:57","TRT02EDTM":"2022-06-27 20:51:57","AP01SDTM":"2019-06-28 02:51:57","AP01EDTM":"2021-06-27 14:51:57","AP02SDTM":"2021-06-27 14:51:57","AP02EDTM":"2022-06-27 20:51:57","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-27","EOSDY":1096,"LSTALVDT":"2022-07-21","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1313,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.6972,"AVALU":"U/L","BASE2":23.6972,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-03 02:51:57","ADY":5,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-14-id-104","SUBJID":"id-104","SITEID":"CAN-14","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-14","INVNAM":"Dr. CAN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.66313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-26","TRTSDTM":"2019-06-28 02:51:57","TRTEDTM":"2022-06-27 20:51:57","TRT01SDTM":"2019-06-28 02:51:57","TRT01EDTM":"2021-06-27 14:51:57","TRT02SDTM":"2021-06-27 14:51:57","TRT02EDTM":"2022-06-27 20:51:57","AP01SDTM":"2019-06-28 02:51:57","AP01EDTM":"2021-06-27 14:51:57","AP02SDTM":"2021-06-27 14:51:57","AP02EDTM":"2022-06-27 20:51:57","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-27","EOSDY":1096,"LSTALVDT":"2022-07-21","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2723,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.7533,"AVALU":"U/L","BASE2":23.6972,"BASE":20.7533,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.94389,"PCHG2":-12.42296,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-15 02:51:57","ADY":79,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-14-id-104","SUBJID":"id-104","SITEID":"CAN-14","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-14","INVNAM":"Dr. CAN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.66313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-26","TRTSDTM":"2019-06-28 02:51:57","TRTEDTM":"2022-06-27 20:51:57","TRT01SDTM":"2019-06-28 02:51:57","TRT01EDTM":"2021-06-27 14:51:57","TRT02SDTM":"2021-06-27 14:51:57","TRT02EDTM":"2022-06-27 20:51:57","AP01SDTM":"2019-06-28 02:51:57","AP01EDTM":"2021-06-27 14:51:57","AP02SDTM":"2021-06-27 14:51:57","AP02EDTM":"2022-06-27 20:51:57","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-27","EOSDY":1096,"LSTALVDT":"2022-07-21","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2424,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.90233,"AVALU":"U/L","BASE2":23.6972,"BASE":20.7533,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.79486,"PCHG2":-16.01397,"CHG":-0.85097,"PCHG":-4.1004,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-04 02:51:57","ADY":190,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-14-id-104","SUBJID":"id-104","SITEID":"CAN-14","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-14","INVNAM":"Dr. CAN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.66313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-26","TRTSDTM":"2019-06-28 02:51:57","TRTEDTM":"2022-06-27 20:51:57","TRT01SDTM":"2019-06-28 02:51:57","TRT01EDTM":"2021-06-27 14:51:57","TRT02SDTM":"2021-06-27 14:51:57","TRT02EDTM":"2022-06-27 20:51:57","AP01SDTM":"2019-06-28 02:51:57","AP01EDTM":"2021-06-27 14:51:57","AP02SDTM":"2021-06-27 14:51:57","AP02EDTM":"2022-06-27 20:51:57","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-27","EOSDY":1096,"LSTALVDT":"2022-07-21","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7026,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.03308,"AVALU":"U/L","BASE2":23.6972,"BASE":20.7533,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.66412,"PCHG2":-40.78168,"CHG":-6.72022,"PCHG":-32.38146,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-15 02:51:57","ADY":232,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-14-id-104","SUBJID":"id-104","SITEID":"CAN-14","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-14","INVNAM":"Dr. CAN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.66313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-26","TRTSDTM":"2019-06-28 02:51:57","TRTEDTM":"2022-06-27 20:51:57","TRT01SDTM":"2019-06-28 02:51:57","TRT01EDTM":"2021-06-27 14:51:57","TRT02SDTM":"2021-06-27 14:51:57","TRT02EDTM":"2022-06-27 20:51:57","AP01SDTM":"2019-06-28 02:51:57","AP01EDTM":"2021-06-27 14:51:57","AP02SDTM":"2021-06-27 14:51:57","AP02EDTM":"2022-06-27 20:51:57","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-27","EOSDY":1096,"LSTALVDT":"2022-07-21","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2434,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.27872,"AVALU":"U/L","BASE2":23.6972,"BASE":20.7533,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.41847,"PCHG2":-5.98583,"CHG":1.52542,"PCHG":7.35024,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-15 02:51:57","ADY":292,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-14-id-104","SUBJID":"id-104","SITEID":"CAN-14","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-14","INVNAM":"Dr. CAN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.66313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-26","TRTSDTM":"2019-06-28 02:51:57","TRTEDTM":"2022-06-27 20:51:57","TRT01SDTM":"2019-06-28 02:51:57","TRT01EDTM":"2021-06-27 14:51:57","TRT02SDTM":"2021-06-27 14:51:57","TRT02EDTM":"2022-06-27 20:51:57","AP01SDTM":"2019-06-28 02:51:57","AP01EDTM":"2021-06-27 14:51:57","AP02SDTM":"2021-06-27 14:51:57","AP02EDTM":"2022-06-27 20:51:57","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-27","EOSDY":1096,"LSTALVDT":"2022-07-21","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8400,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.93949,"AVALU":"U/L","BASE2":23.6972,"BASE":20.7533,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.7577,"PCHG2":-11.63726,"CHG":0.18619,"PCHG":0.89715,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-30 02:51:57","ADY":763,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-14-id-104","SUBJID":"id-104","SITEID":"CAN-14","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-14","INVNAM":"Dr. CAN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.66313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-26","TRTSDTM":"2019-06-28 02:51:57","TRTEDTM":"2022-06-27 20:51:57","TRT01SDTM":"2019-06-28 02:51:57","TRT01EDTM":"2021-06-27 14:51:57","TRT02SDTM":"2021-06-27 14:51:57","TRT02EDTM":"2022-06-27 20:51:57","AP01SDTM":"2019-06-28 02:51:57","AP01EDTM":"2021-06-27 14:51:57","AP02SDTM":"2021-06-27 14:51:57","AP02EDTM":"2022-06-27 20:51:57","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-27","EOSDY":1096,"LSTALVDT":"2022-07-21","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4907,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.8697,"AVALU":"U/L","BASE2":23.6972,"BASE":20.7533,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.8275,"PCHG2":-24.5915,"CHG":-2.8836,"PCHG":-13.89467,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-17 02:51:57","ADY":993,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-14-id-104","SUBJID":"id-104","SITEID":"CAN-14","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-14","INVNAM":"Dr. CAN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.66313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-26","TRTSDTM":"2019-06-28 02:51:57","TRTEDTM":"2022-06-27 20:51:57","TRT01SDTM":"2019-06-28 02:51:57","TRT01EDTM":"2021-06-27 14:51:57","TRT02SDTM":"2021-06-27 14:51:57","TRT02EDTM":"2022-06-27 20:51:57","AP01SDTM":"2019-06-28 02:51:57","AP01EDTM":"2021-06-27 14:51:57","AP02SDTM":"2021-06-27 14:51:57","AP02EDTM":"2022-06-27 20:51:57","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-27","EOSDY":1096,"LSTALVDT":"2022-07-21","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2942,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.88899,"AVALU":"mg/L","BASE2":8.88899,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-03 02:51:57","ADY":5,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-14-id-104","SUBJID":"id-104","SITEID":"CAN-14","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-14","INVNAM":"Dr. CAN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.66313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-26","TRTSDTM":"2019-06-28 02:51:57","TRTEDTM":"2022-06-27 20:51:57","TRT01SDTM":"2019-06-28 02:51:57","TRT01EDTM":"2021-06-27 14:51:57","TRT02SDTM":"2021-06-27 14:51:57","TRT02EDTM":"2022-06-27 20:51:57","AP01SDTM":"2019-06-28 02:51:57","AP01EDTM":"2021-06-27 14:51:57","AP02SDTM":"2021-06-27 14:51:57","AP02EDTM":"2022-06-27 20:51:57","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-27","EOSDY":1096,"LSTALVDT":"2022-07-21","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8306,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.339,"AVALU":"mg/L","BASE2":8.88899,"BASE":9.339,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.45001,"PCHG2":5.06253,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-15 02:51:57","ADY":79,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-14-id-104","SUBJID":"id-104","SITEID":"CAN-14","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-14","INVNAM":"Dr. CAN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.66313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-26","TRTSDTM":"2019-06-28 02:51:57","TRTEDTM":"2022-06-27 20:51:57","TRT01SDTM":"2019-06-28 02:51:57","TRT01EDTM":"2021-06-27 14:51:57","TRT02SDTM":"2021-06-27 14:51:57","TRT02EDTM":"2022-06-27 20:51:57","AP01SDTM":"2019-06-28 02:51:57","AP01EDTM":"2021-06-27 14:51:57","AP02SDTM":"2021-06-27 14:51:57","AP02EDTM":"2022-06-27 20:51:57","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-27","EOSDY":1096,"LSTALVDT":"2022-07-21","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8102,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.5066,"AVALU":"mg/L","BASE2":8.88899,"BASE":9.339,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.61761,"PCHG2":6.94798,"CHG":0.1676,"PCHG":1.79461,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-04 02:51:57","ADY":190,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-14-id-104","SUBJID":"id-104","SITEID":"CAN-14","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-14","INVNAM":"Dr. CAN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.66313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-26","TRTSDTM":"2019-06-28 02:51:57","TRTEDTM":"2022-06-27 20:51:57","TRT01SDTM":"2019-06-28 02:51:57","TRT01EDTM":"2021-06-27 14:51:57","TRT02SDTM":"2021-06-27 14:51:57","TRT02EDTM":"2022-06-27 20:51:57","AP01SDTM":"2019-06-28 02:51:57","AP01EDTM":"2021-06-27 14:51:57","AP02SDTM":"2021-06-27 14:51:57","AP02EDTM":"2022-06-27 20:51:57","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-27","EOSDY":1096,"LSTALVDT":"2022-07-21","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2147,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.85177,"AVALU":"mg/L","BASE2":8.88899,"BASE":9.339,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03722,"PCHG2":-0.41877,"CHG":-0.48723,"PCHG":-5.21717,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-15 02:51:57","ADY":232,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-14-id-104","SUBJID":"id-104","SITEID":"CAN-14","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-14","INVNAM":"Dr. CAN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.66313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-26","TRTSDTM":"2019-06-28 02:51:57","TRTEDTM":"2022-06-27 20:51:57","TRT01SDTM":"2019-06-28 02:51:57","TRT01EDTM":"2021-06-27 14:51:57","TRT02SDTM":"2021-06-27 14:51:57","TRT02EDTM":"2022-06-27 20:51:57","AP01SDTM":"2019-06-28 02:51:57","AP01EDTM":"2021-06-27 14:51:57","AP02SDTM":"2021-06-27 14:51:57","AP02EDTM":"2022-06-27 20:51:57","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-27","EOSDY":1096,"LSTALVDT":"2022-07-21","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4869,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.59945,"AVALU":"mg/L","BASE2":8.88899,"BASE":9.339,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.71046,"PCHG2":30.49228,"CHG":2.26045,"PCHG":24.2044,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-04-15 02:51:57","ADY":292,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-14-id-104","SUBJID":"id-104","SITEID":"CAN-14","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-14","INVNAM":"Dr. CAN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.66313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-26","TRTSDTM":"2019-06-28 02:51:57","TRTEDTM":"2022-06-27 20:51:57","TRT01SDTM":"2019-06-28 02:51:57","TRT01EDTM":"2021-06-27 14:51:57","TRT02SDTM":"2021-06-27 14:51:57","TRT02EDTM":"2022-06-27 20:51:57","AP01SDTM":"2019-06-28 02:51:57","AP01EDTM":"2021-06-27 14:51:57","AP02SDTM":"2021-06-27 14:51:57","AP02EDTM":"2022-06-27 20:51:57","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-27","EOSDY":1096,"LSTALVDT":"2022-07-21","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1563,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.90498,"AVALU":"mg/L","BASE2":8.88899,"BASE":9.339,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.01599,"PCHG2":11.42971,"CHG":0.56598,"PCHG":6.06037,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-30 02:51:57","ADY":763,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-14-id-104","SUBJID":"id-104","SITEID":"CAN-14","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-14","INVNAM":"Dr. CAN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.66313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-26","TRTSDTM":"2019-06-28 02:51:57","TRTEDTM":"2022-06-27 20:51:57","TRT01SDTM":"2019-06-28 02:51:57","TRT01EDTM":"2021-06-27 14:51:57","TRT02SDTM":"2021-06-27 14:51:57","TRT02EDTM":"2022-06-27 20:51:57","AP01SDTM":"2019-06-28 02:51:57","AP01EDTM":"2021-06-27 14:51:57","AP02SDTM":"2021-06-27 14:51:57","AP02EDTM":"2022-06-27 20:51:57","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-27","EOSDY":1096,"LSTALVDT":"2022-07-21","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6933,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":12.11907,"AVALU":"mg/L","BASE2":8.88899,"BASE":9.339,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.23009,"PCHG2":36.33805,"CHG":2.78008,"PCHG":29.76849,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-03-17 02:51:57","ADY":993,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-14-id-104","SUBJID":"id-104","SITEID":"CAN-14","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-14","INVNAM":"Dr. CAN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.66313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-26","TRTSDTM":"2019-06-28 02:51:57","TRTEDTM":"2022-06-27 20:51:57","TRT01SDTM":"2019-06-28 02:51:57","TRT01EDTM":"2021-06-27 14:51:57","TRT02SDTM":"2021-06-27 14:51:57","TRT02EDTM":"2022-06-27 20:51:57","AP01SDTM":"2019-06-28 02:51:57","AP01EDTM":"2021-06-27 14:51:57","AP02SDTM":"2021-06-27 14:51:57","AP02EDTM":"2022-06-27 20:51:57","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-27","EOSDY":1096,"LSTALVDT":"2022-07-21","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":579,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84565,"AVALU":"g/L","BASE2":2.84565,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-03 02:51:57","ADY":5,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-14-id-104","SUBJID":"id-104","SITEID":"CAN-14","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-14","INVNAM":"Dr. CAN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.66313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-26","TRTSDTM":"2019-06-28 02:51:57","TRTEDTM":"2022-06-27 20:51:57","TRT01SDTM":"2019-06-28 02:51:57","TRT01EDTM":"2021-06-27 14:51:57","TRT02SDTM":"2021-06-27 14:51:57","TRT02EDTM":"2022-06-27 20:51:57","AP01SDTM":"2019-06-28 02:51:57","AP01EDTM":"2021-06-27 14:51:57","AP02SDTM":"2021-06-27 14:51:57","AP02EDTM":"2022-06-27 20:51:57","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-27","EOSDY":1096,"LSTALVDT":"2022-07-21","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6230,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94333,"AVALU":"g/L","BASE2":2.84565,"BASE":2.94333,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.09768,"PCHG2":3.43261,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-15 02:51:57","ADY":79,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-14-id-104","SUBJID":"id-104","SITEID":"CAN-14","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-14","INVNAM":"Dr. CAN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.66313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-26","TRTSDTM":"2019-06-28 02:51:57","TRTEDTM":"2022-06-27 20:51:57","TRT01SDTM":"2019-06-28 02:51:57","TRT01EDTM":"2021-06-27 14:51:57","TRT02SDTM":"2021-06-27 14:51:57","TRT02EDTM":"2022-06-27 20:51:57","AP01SDTM":"2019-06-28 02:51:57","AP01EDTM":"2021-06-27 14:51:57","AP02SDTM":"2021-06-27 14:51:57","AP02EDTM":"2022-06-27 20:51:57","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-27","EOSDY":1096,"LSTALVDT":"2022-07-21","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5857,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91652,"AVALU":"g/L","BASE2":2.84565,"BASE":2.94333,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07087,"PCHG2":2.49039,"CHG":-0.02681,"PCHG":-0.91095,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-04 02:51:57","ADY":190,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-14-id-104","SUBJID":"id-104","SITEID":"CAN-14","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-14","INVNAM":"Dr. CAN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.66313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-26","TRTSDTM":"2019-06-28 02:51:57","TRTEDTM":"2022-06-27 20:51:57","TRT01SDTM":"2019-06-28 02:51:57","TRT01EDTM":"2021-06-27 14:51:57","TRT02SDTM":"2021-06-27 14:51:57","TRT02EDTM":"2022-06-27 20:51:57","AP01SDTM":"2019-06-28 02:51:57","AP01EDTM":"2021-06-27 14:51:57","AP02SDTM":"2021-06-27 14:51:57","AP02EDTM":"2022-06-27 20:51:57","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-27","EOSDY":1096,"LSTALVDT":"2022-07-21","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2824,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86601,"AVALU":"g/L","BASE2":2.84565,"BASE":2.94333,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02035,"PCHG2":0.71529,"CHG":-0.07733,"PCHG":-2.62714,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-15 02:51:57","ADY":232,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-14-id-104","SUBJID":"id-104","SITEID":"CAN-14","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-14","INVNAM":"Dr. CAN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.66313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-26","TRTSDTM":"2019-06-28 02:51:57","TRTEDTM":"2022-06-27 20:51:57","TRT01SDTM":"2019-06-28 02:51:57","TRT01EDTM":"2021-06-27 14:51:57","TRT02SDTM":"2021-06-27 14:51:57","TRT02EDTM":"2022-06-27 20:51:57","AP01SDTM":"2019-06-28 02:51:57","AP01EDTM":"2021-06-27 14:51:57","AP02SDTM":"2021-06-27 14:51:57","AP02EDTM":"2022-06-27 20:51:57","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-27","EOSDY":1096,"LSTALVDT":"2022-07-21","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5132,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80083,"AVALU":"g/L","BASE2":2.84565,"BASE":2.94333,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04482,"PCHG2":-1.5752,"CHG":-0.1425,"PCHG":-4.84161,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-15 02:51:57","ADY":292,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-14-id-104","SUBJID":"id-104","SITEID":"CAN-14","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-14","INVNAM":"Dr. CAN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.66313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-26","TRTSDTM":"2019-06-28 02:51:57","TRTEDTM":"2022-06-27 20:51:57","TRT01SDTM":"2019-06-28 02:51:57","TRT01EDTM":"2021-06-27 14:51:57","TRT02SDTM":"2021-06-27 14:51:57","TRT02EDTM":"2022-06-27 20:51:57","AP01SDTM":"2019-06-28 02:51:57","AP01EDTM":"2021-06-27 14:51:57","AP02SDTM":"2021-06-27 14:51:57","AP02EDTM":"2022-06-27 20:51:57","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-27","EOSDY":1096,"LSTALVDT":"2022-07-21","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6346,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9126,"AVALU":"g/L","BASE2":2.84565,"BASE":2.94333,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06695,"PCHG2":2.35254,"CHG":-0.03073,"PCHG":-1.04422,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-30 02:51:57","ADY":763,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-14-id-104","SUBJID":"id-104","SITEID":"CAN-14","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-14","INVNAM":"Dr. CAN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.66313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-26","TRTSDTM":"2019-06-28 02:51:57","TRTEDTM":"2022-06-27 20:51:57","TRT01SDTM":"2019-06-28 02:51:57","TRT01EDTM":"2021-06-27 14:51:57","TRT02SDTM":"2021-06-27 14:51:57","TRT02EDTM":"2022-06-27 20:51:57","AP01SDTM":"2019-06-28 02:51:57","AP01EDTM":"2021-06-27 14:51:57","AP02SDTM":"2021-06-27 14:51:57","AP02EDTM":"2022-06-27 20:51:57","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-27","EOSDY":1096,"LSTALVDT":"2022-07-21","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3249,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94743,"AVALU":"g/L","BASE2":2.84565,"BASE":2.94333,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10178,"PCHG2":3.57655,"CHG":0.0041,"PCHG":0.13917,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-17 02:51:57","ADY":993,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-324","SUBJID":"id-324","SITEID":"CAN-4","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.34637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 08:05:15","TRTEDTM":"2023-11-18 02:05:15","TRT01SDTM":"2020-11-17 08:05:15","TRT01EDTM":"2022-11-17 20:05:15","TRT02SDTM":"2022-11-17 20:05:15","TRT02EDTM":"2023-11-18 02:05:15","AP01SDTM":"2020-11-17 08:05:15","AP01EDTM":"2022-11-17 20:05:15","AP02SDTM":"2022-11-17 20:05:15","AP02EDTM":"2023-11-18 02:05:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-03","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2324,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.73881,"AVALU":"U/L","BASE2":32.73881,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-14 08:05:15","ADY":89,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-324","SUBJID":"id-324","SITEID":"CAN-4","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.34637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 08:05:15","TRTEDTM":"2023-11-18 02:05:15","TRT01SDTM":"2020-11-17 08:05:15","TRT01EDTM":"2022-11-17 20:05:15","TRT02SDTM":"2022-11-17 20:05:15","TRT02EDTM":"2023-11-18 02:05:15","AP01SDTM":"2020-11-17 08:05:15","AP01EDTM":"2022-11-17 20:05:15","AP02SDTM":"2022-11-17 20:05:15","AP02EDTM":"2023-11-18 02:05:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-03","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5016,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.59341,"AVALU":"U/L","BASE2":32.73881,"BASE":14.59341,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-18.1454,"PCHG2":-55.42474,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-25 08:05:15","ADY":159,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-324","SUBJID":"id-324","SITEID":"CAN-4","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.34637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 08:05:15","TRTEDTM":"2023-11-18 02:05:15","TRT01SDTM":"2020-11-17 08:05:15","TRT01EDTM":"2022-11-17 20:05:15","TRT02SDTM":"2022-11-17 20:05:15","TRT02EDTM":"2023-11-18 02:05:15","AP01SDTM":"2020-11-17 08:05:15","AP01EDTM":"2022-11-17 20:05:15","AP02SDTM":"2022-11-17 20:05:15","AP02EDTM":"2023-11-18 02:05:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-03","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4340,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.09717,"AVALU":"U/L","BASE2":32.73881,"BASE":14.59341,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.64165,"PCHG2":-32.50468,"CHG":7.50376,"PCHG":51.4188,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-27 08:05:15","ADY":679,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-324","SUBJID":"id-324","SITEID":"CAN-4","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.34637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 08:05:15","TRTEDTM":"2023-11-18 02:05:15","TRT01SDTM":"2020-11-17 08:05:15","TRT01EDTM":"2022-11-17 20:05:15","TRT02SDTM":"2022-11-17 20:05:15","TRT02EDTM":"2023-11-18 02:05:15","AP01SDTM":"2020-11-17 08:05:15","AP01EDTM":"2022-11-17 20:05:15","AP02SDTM":"2022-11-17 20:05:15","AP02EDTM":"2023-11-18 02:05:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-03","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8024,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.48136,"AVALU":"U/L","BASE2":32.73881,"BASE":14.59341,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.25745,"PCHG2":-0.78638,"CHG":17.88795,"PCHG":122.57555,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-28 08:05:15","ADY":741,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-324","SUBJID":"id-324","SITEID":"CAN-4","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.34637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 08:05:15","TRTEDTM":"2023-11-18 02:05:15","TRT01SDTM":"2020-11-17 08:05:15","TRT01EDTM":"2022-11-17 20:05:15","TRT02SDTM":"2022-11-17 20:05:15","TRT02EDTM":"2023-11-18 02:05:15","AP01SDTM":"2020-11-17 08:05:15","AP01EDTM":"2022-11-17 20:05:15","AP02SDTM":"2022-11-17 20:05:15","AP02EDTM":"2023-11-18 02:05:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-03","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1264,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.64648,"AVALU":"U/L","BASE2":32.73881,"BASE":14.59341,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-28.09233,"PCHG2":-85.80743,"CHG":-9.94693,"PCHG":-68.16042,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2022-12-11 08:05:15","ADY":754,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-324","SUBJID":"id-324","SITEID":"CAN-4","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.34637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 08:05:15","TRTEDTM":"2023-11-18 02:05:15","TRT01SDTM":"2020-11-17 08:05:15","TRT01EDTM":"2022-11-17 20:05:15","TRT02SDTM":"2022-11-17 20:05:15","TRT02EDTM":"2023-11-18 02:05:15","AP01SDTM":"2020-11-17 08:05:15","AP01EDTM":"2022-11-17 20:05:15","AP02SDTM":"2022-11-17 20:05:15","AP02EDTM":"2023-11-18 02:05:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-03","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2164,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.09217,"AVALU":"U/L","BASE2":32.73881,"BASE":14.59341,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.64664,"PCHG2":-1.97515,"CHG":17.49876,"PCHG":119.90867,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-29 08:05:15","ADY":862,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-324","SUBJID":"id-324","SITEID":"CAN-4","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.34637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 08:05:15","TRTEDTM":"2023-11-18 02:05:15","TRT01SDTM":"2020-11-17 08:05:15","TRT01EDTM":"2022-11-17 20:05:15","TRT02SDTM":"2022-11-17 20:05:15","TRT02EDTM":"2023-11-18 02:05:15","AP01SDTM":"2020-11-17 08:05:15","AP01EDTM":"2022-11-17 20:05:15","AP02SDTM":"2022-11-17 20:05:15","AP02EDTM":"2023-11-18 02:05:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-03","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4101,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.95503,"AVALU":"U/L","BASE2":32.73881,"BASE":14.59341,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.78378,"PCHG2":-39.04778,"CHG":5.36162,"PCHG":36.74003,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-11-05 08:05:15","ADY":1083,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-324","SUBJID":"id-324","SITEID":"CAN-4","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.34637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 08:05:15","TRTEDTM":"2023-11-18 02:05:15","TRT01SDTM":"2020-11-17 08:05:15","TRT01EDTM":"2022-11-17 20:05:15","TRT02SDTM":"2022-11-17 20:05:15","TRT02EDTM":"2023-11-18 02:05:15","AP01SDTM":"2020-11-17 08:05:15","AP01EDTM":"2022-11-17 20:05:15","AP02SDTM":"2022-11-17 20:05:15","AP02EDTM":"2023-11-18 02:05:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-03","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3397,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.4693,"AVALU":"mg/L","BASE2":7.4693,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-02-14 08:05:15","ADY":89,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-324","SUBJID":"id-324","SITEID":"CAN-4","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.34637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 08:05:15","TRTEDTM":"2023-11-18 02:05:15","TRT01SDTM":"2020-11-17 08:05:15","TRT01EDTM":"2022-11-17 20:05:15","TRT02SDTM":"2022-11-17 20:05:15","TRT02EDTM":"2023-11-18 02:05:15","AP01SDTM":"2020-11-17 08:05:15","AP01EDTM":"2022-11-17 20:05:15","AP02SDTM":"2022-11-17 20:05:15","AP02EDTM":"2023-11-18 02:05:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-03","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2954,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.76369,"AVALU":"mg/L","BASE2":7.4693,"BASE":8.76369,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.29439,"PCHG2":17.32947,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-25 08:05:15","ADY":159,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-324","SUBJID":"id-324","SITEID":"CAN-4","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.34637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 08:05:15","TRTEDTM":"2023-11-18 02:05:15","TRT01SDTM":"2020-11-17 08:05:15","TRT01EDTM":"2022-11-17 20:05:15","TRT02SDTM":"2022-11-17 20:05:15","TRT02EDTM":"2023-11-18 02:05:15","AP01SDTM":"2020-11-17 08:05:15","AP01EDTM":"2022-11-17 20:05:15","AP02SDTM":"2022-11-17 20:05:15","AP02EDTM":"2023-11-18 02:05:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-03","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8249,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.96186,"AVALU":"mg/L","BASE2":7.4693,"BASE":8.76369,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.49256,"PCHG2":46.75892,"CHG":2.19817,"PCHG":25.08275,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-09-27 08:05:15","ADY":679,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-324","SUBJID":"id-324","SITEID":"CAN-4","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.34637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 08:05:15","TRTEDTM":"2023-11-18 02:05:15","TRT01SDTM":"2020-11-17 08:05:15","TRT01EDTM":"2022-11-17 20:05:15","TRT02SDTM":"2022-11-17 20:05:15","TRT02EDTM":"2023-11-18 02:05:15","AP01SDTM":"2020-11-17 08:05:15","AP01EDTM":"2022-11-17 20:05:15","AP02SDTM":"2022-11-17 20:05:15","AP02EDTM":"2023-11-18 02:05:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-03","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7371,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.9011,"AVALU":"mg/L","BASE2":7.4693,"BASE":8.76369,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.4318,"PCHG2":5.78097,"CHG":-0.86259,"PCHG":-9.84279,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-11-28 08:05:15","ADY":741,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-324","SUBJID":"id-324","SITEID":"CAN-4","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.34637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 08:05:15","TRTEDTM":"2023-11-18 02:05:15","TRT01SDTM":"2020-11-17 08:05:15","TRT01EDTM":"2022-11-17 20:05:15","TRT02SDTM":"2022-11-17 20:05:15","TRT02EDTM":"2023-11-18 02:05:15","AP01SDTM":"2020-11-17 08:05:15","AP01EDTM":"2022-11-17 20:05:15","AP02SDTM":"2022-11-17 20:05:15","AP02EDTM":"2023-11-18 02:05:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-03","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2681,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.99298,"AVALU":"mg/L","BASE2":7.4693,"BASE":8.76369,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.52368,"PCHG2":7.01107,"CHG":-0.77071,"PCHG":-8.79438,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-12-11 08:05:15","ADY":754,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-324","SUBJID":"id-324","SITEID":"CAN-4","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.34637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 08:05:15","TRTEDTM":"2023-11-18 02:05:15","TRT01SDTM":"2020-11-17 08:05:15","TRT01EDTM":"2022-11-17 20:05:15","TRT02SDTM":"2022-11-17 20:05:15","TRT02EDTM":"2023-11-18 02:05:15","AP01SDTM":"2020-11-17 08:05:15","AP01EDTM":"2022-11-17 20:05:15","AP02SDTM":"2022-11-17 20:05:15","AP02EDTM":"2023-11-18 02:05:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-03","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3168,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.29411,"AVALU":"mg/L","BASE2":7.4693,"BASE":8.76369,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.82481,"PCHG2":11.04264,"CHG":-0.46958,"PCHG":-5.35827,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-29 08:05:15","ADY":862,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-324","SUBJID":"id-324","SITEID":"CAN-4","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.34637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 08:05:15","TRTEDTM":"2023-11-18 02:05:15","TRT01SDTM":"2020-11-17 08:05:15","TRT01EDTM":"2022-11-17 20:05:15","TRT02SDTM":"2022-11-17 20:05:15","TRT02EDTM":"2023-11-18 02:05:15","AP01SDTM":"2020-11-17 08:05:15","AP01EDTM":"2022-11-17 20:05:15","AP02SDTM":"2022-11-17 20:05:15","AP02EDTM":"2023-11-18 02:05:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-03","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":726,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.64374,"AVALU":"mg/L","BASE2":7.4693,"BASE":8.76369,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.17444,"PCHG2":15.72359,"CHG":-0.11995,"PCHG":-1.36869,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-11-05 08:05:15","ADY":1083,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-324","SUBJID":"id-324","SITEID":"CAN-4","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.34637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 08:05:15","TRTEDTM":"2023-11-18 02:05:15","TRT01SDTM":"2020-11-17 08:05:15","TRT01EDTM":"2022-11-17 20:05:15","TRT02SDTM":"2022-11-17 20:05:15","TRT02EDTM":"2023-11-18 02:05:15","AP01SDTM":"2020-11-17 08:05:15","AP01EDTM":"2022-11-17 20:05:15","AP02SDTM":"2022-11-17 20:05:15","AP02EDTM":"2023-11-18 02:05:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-03","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":243,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7384,"AVALU":"g/L","BASE2":2.7384,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-14 08:05:15","ADY":89,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-324","SUBJID":"id-324","SITEID":"CAN-4","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.34637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 08:05:15","TRTEDTM":"2023-11-18 02:05:15","TRT01SDTM":"2020-11-17 08:05:15","TRT01EDTM":"2022-11-17 20:05:15","TRT02SDTM":"2022-11-17 20:05:15","TRT02EDTM":"2023-11-18 02:05:15","AP01SDTM":"2020-11-17 08:05:15","AP01EDTM":"2022-11-17 20:05:15","AP02SDTM":"2022-11-17 20:05:15","AP02EDTM":"2023-11-18 02:05:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-03","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6216,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82978,"AVALU":"g/L","BASE2":2.7384,"BASE":2.82978,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.09138,"PCHG2":3.337,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-25 08:05:15","ADY":159,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-324","SUBJID":"id-324","SITEID":"CAN-4","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.34637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 08:05:15","TRTEDTM":"2023-11-18 02:05:15","TRT01SDTM":"2020-11-17 08:05:15","TRT01EDTM":"2022-11-17 20:05:15","TRT02SDTM":"2022-11-17 20:05:15","TRT02EDTM":"2023-11-18 02:05:15","AP01SDTM":"2020-11-17 08:05:15","AP01EDTM":"2022-11-17 20:05:15","AP02SDTM":"2022-11-17 20:05:15","AP02EDTM":"2023-11-18 02:05:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-03","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8186,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05505,"AVALU":"g/L","BASE2":2.7384,"BASE":2.82978,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.31664,"PCHG2":11.56309,"CHG":0.22526,"PCHG":7.96045,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-09-27 08:05:15","ADY":679,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-324","SUBJID":"id-324","SITEID":"CAN-4","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.34637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 08:05:15","TRTEDTM":"2023-11-18 02:05:15","TRT01SDTM":"2020-11-17 08:05:15","TRT01EDTM":"2022-11-17 20:05:15","TRT02SDTM":"2022-11-17 20:05:15","TRT02EDTM":"2023-11-18 02:05:15","AP01SDTM":"2020-11-17 08:05:15","AP01EDTM":"2022-11-17 20:05:15","AP02SDTM":"2022-11-17 20:05:15","AP02EDTM":"2023-11-18 02:05:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-03","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6743,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85889,"AVALU":"g/L","BASE2":2.7384,"BASE":2.82978,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12048,"PCHG2":4.3997,"CHG":0.0291,"PCHG":1.02839,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-28 08:05:15","ADY":741,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-324","SUBJID":"id-324","SITEID":"CAN-4","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.34637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 08:05:15","TRTEDTM":"2023-11-18 02:05:15","TRT01SDTM":"2020-11-17 08:05:15","TRT01EDTM":"2022-11-17 20:05:15","TRT02SDTM":"2022-11-17 20:05:15","TRT02EDTM":"2023-11-18 02:05:15","AP01SDTM":"2020-11-17 08:05:15","AP01EDTM":"2022-11-17 20:05:15","AP02SDTM":"2022-11-17 20:05:15","AP02EDTM":"2023-11-18 02:05:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-03","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4916,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.10898,"AVALU":"g/L","BASE2":2.7384,"BASE":2.82978,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.37058,"PCHG2":13.53265,"CHG":0.2792,"PCHG":9.86642,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-12-11 08:05:15","ADY":754,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-324","SUBJID":"id-324","SITEID":"CAN-4","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.34637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 08:05:15","TRTEDTM":"2023-11-18 02:05:15","TRT01SDTM":"2020-11-17 08:05:15","TRT01EDTM":"2022-11-17 20:05:15","TRT02SDTM":"2022-11-17 20:05:15","TRT02EDTM":"2023-11-18 02:05:15","AP01SDTM":"2020-11-17 08:05:15","AP01EDTM":"2022-11-17 20:05:15","AP02SDTM":"2022-11-17 20:05:15","AP02EDTM":"2023-11-18 02:05:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-03","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5024,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76083,"AVALU":"g/L","BASE2":2.7384,"BASE":2.82978,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02243,"PCHG2":0.81906,"CHG":-0.06895,"PCHG":-2.43663,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-29 08:05:15","ADY":862,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-324","SUBJID":"id-324","SITEID":"CAN-4","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.34637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 08:05:15","TRTEDTM":"2023-11-18 02:05:15","TRT01SDTM":"2020-11-17 08:05:15","TRT01EDTM":"2022-11-17 20:05:15","TRT02SDTM":"2022-11-17 20:05:15","TRT02EDTM":"2023-11-18 02:05:15","AP01SDTM":"2020-11-17 08:05:15","AP01EDTM":"2022-11-17 20:05:15","AP02SDTM":"2022-11-17 20:05:15","AP02EDTM":"2023-11-18 02:05:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-03","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2227,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83772,"AVALU":"g/L","BASE2":2.7384,"BASE":2.82978,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09932,"PCHG2":3.62676,"CHG":0.00793,"PCHG":0.2804,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-11-05 08:05:15","ADY":1083,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-331","SUBJID":"id-331","SITEID":"CAN-4","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.65637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 04:59:48","TRTEDTM":"2023-05-03 22:59:48","TRT01SDTM":"2020-05-03 04:59:48","TRT01EDTM":"2022-05-03 16:59:48","TRT02SDTM":"2022-05-03 16:59:48","TRT02EDTM":"2023-05-03 22:59:48","AP01SDTM":"2020-05-03 04:59:48","AP01EDTM":"2022-05-03 16:59:48","AP02SDTM":"2022-05-03 16:59:48","AP02EDTM":"2023-05-03 22:59:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-03","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4386,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.62965,"AVALU":"U/L","BASE2":29.62965,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-3","ADTM":"2020-12-30 04:59:48","ADY":241,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-331","SUBJID":"id-331","SITEID":"CAN-4","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.65637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 04:59:48","TRTEDTM":"2023-05-03 22:59:48","TRT01SDTM":"2020-05-03 04:59:48","TRT01EDTM":"2022-05-03 16:59:48","TRT02SDTM":"2022-05-03 16:59:48","TRT02EDTM":"2023-05-03 22:59:48","AP01SDTM":"2020-05-03 04:59:48","AP01EDTM":"2022-05-03 16:59:48","AP02SDTM":"2022-05-03 16:59:48","AP02EDTM":"2023-05-03 22:59:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-03","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2126,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.95896,"AVALU":"U/L","BASE2":29.62965,"BASE":4.95896,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-24.67068,"PCHG2":-83.26351,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2021-04-20 04:59:48","ADY":352,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-331","SUBJID":"id-331","SITEID":"CAN-4","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.65637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 04:59:48","TRTEDTM":"2023-05-03 22:59:48","TRT01SDTM":"2020-05-03 04:59:48","TRT01EDTM":"2022-05-03 16:59:48","TRT02SDTM":"2022-05-03 16:59:48","TRT02EDTM":"2023-05-03 22:59:48","AP01SDTM":"2020-05-03 04:59:48","AP01EDTM":"2022-05-03 16:59:48","AP02SDTM":"2022-05-03 16:59:48","AP02EDTM":"2023-05-03 22:59:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-03","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7957,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.02091,"AVALU":"U/L","BASE2":29.62965,"BASE":4.95896,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.60874,"PCHG2":-29.05447,"CHG":16.06195,"PCHG":323.89735,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-11-27 04:59:48","ADY":573,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-331","SUBJID":"id-331","SITEID":"CAN-4","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.65637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 04:59:48","TRTEDTM":"2023-05-03 22:59:48","TRT01SDTM":"2020-05-03 04:59:48","TRT01EDTM":"2022-05-03 16:59:48","TRT02SDTM":"2022-05-03 16:59:48","TRT02EDTM":"2023-05-03 22:59:48","AP01SDTM":"2020-05-03 04:59:48","AP01EDTM":"2022-05-03 16:59:48","AP02SDTM":"2022-05-03 16:59:48","AP02EDTM":"2023-05-03 22:59:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-03","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7347,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.85298,"AVALU":"U/L","BASE2":29.62965,"BASE":4.95896,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.77667,"PCHG2":-39.74624,"CHG":12.89401,"PCHG":260.01435,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-12-09 04:59:48","ADY":585,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-331","SUBJID":"id-331","SITEID":"CAN-4","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.65637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 04:59:48","TRTEDTM":"2023-05-03 22:59:48","TRT01SDTM":"2020-05-03 04:59:48","TRT01EDTM":"2022-05-03 16:59:48","TRT02SDTM":"2022-05-03 16:59:48","TRT02EDTM":"2023-05-03 22:59:48","AP01SDTM":"2020-05-03 04:59:48","AP01EDTM":"2022-05-03 16:59:48","AP02SDTM":"2022-05-03 16:59:48","AP02EDTM":"2023-05-03 22:59:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-03","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":302,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.92421,"AVALU":"U/L","BASE2":29.62965,"BASE":4.95896,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-27.70544,"PCHG2":-93.50581,"CHG":-3.03476,"PCHG":-61.19742,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2021-12-20 04:59:48","ADY":596,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-331","SUBJID":"id-331","SITEID":"CAN-4","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.65637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 04:59:48","TRTEDTM":"2023-05-03 22:59:48","TRT01SDTM":"2020-05-03 04:59:48","TRT01EDTM":"2022-05-03 16:59:48","TRT02SDTM":"2022-05-03 16:59:48","TRT02EDTM":"2023-05-03 22:59:48","AP01SDTM":"2020-05-03 04:59:48","AP01EDTM":"2022-05-03 16:59:48","AP02SDTM":"2022-05-03 16:59:48","AP02EDTM":"2023-05-03 22:59:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-03","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5435,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.72578,"AVALU":"U/L","BASE2":29.62965,"BASE":4.95896,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-23.90387,"PCHG2":-80.67552,"CHG":0.76681,"PCHG":15.46317,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2022-03-03 04:59:48","ADY":669,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-331","SUBJID":"id-331","SITEID":"CAN-4","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.65637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 04:59:48","TRTEDTM":"2023-05-03 22:59:48","TRT01SDTM":"2020-05-03 04:59:48","TRT01EDTM":"2022-05-03 16:59:48","TRT02SDTM":"2022-05-03 16:59:48","TRT02EDTM":"2023-05-03 22:59:48","AP01SDTM":"2020-05-03 04:59:48","AP01EDTM":"2022-05-03 16:59:48","AP02SDTM":"2022-05-03 16:59:48","AP02EDTM":"2023-05-03 22:59:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-03","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5804,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.13989,"AVALU":"U/L","BASE2":29.62965,"BASE":4.95896,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-24.48976,"PCHG2":-82.65289,"CHG":0.18093,"PCHG":3.64846,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-3","ADTM":"2022-12-22 04:59:48","ADY":963,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-331","SUBJID":"id-331","SITEID":"CAN-4","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.65637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 04:59:48","TRTEDTM":"2023-05-03 22:59:48","TRT01SDTM":"2020-05-03 04:59:48","TRT01EDTM":"2022-05-03 16:59:48","TRT02SDTM":"2022-05-03 16:59:48","TRT02EDTM":"2023-05-03 22:59:48","AP01SDTM":"2020-05-03 04:59:48","AP01EDTM":"2022-05-03 16:59:48","AP02SDTM":"2022-05-03 16:59:48","AP02EDTM":"2023-05-03 22:59:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-03","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5685,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.90637,"AVALU":"mg/L","BASE2":9.90637,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-30 04:59:48","ADY":241,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-331","SUBJID":"id-331","SITEID":"CAN-4","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.65637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 04:59:48","TRTEDTM":"2023-05-03 22:59:48","TRT01SDTM":"2020-05-03 04:59:48","TRT01EDTM":"2022-05-03 16:59:48","TRT02SDTM":"2022-05-03 16:59:48","TRT02EDTM":"2023-05-03 22:59:48","AP01SDTM":"2020-05-03 04:59:48","AP01EDTM":"2022-05-03 16:59:48","AP02SDTM":"2022-05-03 16:59:48","AP02EDTM":"2023-05-03 22:59:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-03","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":226,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.02468,"AVALU":"mg/L","BASE2":9.90637,"BASE":8.02468,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.88169,"PCHG2":-18.99472,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-20 04:59:48","ADY":352,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-331","SUBJID":"id-331","SITEID":"CAN-4","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.65637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 04:59:48","TRTEDTM":"2023-05-03 22:59:48","TRT01SDTM":"2020-05-03 04:59:48","TRT01EDTM":"2022-05-03 16:59:48","TRT02SDTM":"2022-05-03 16:59:48","TRT02EDTM":"2023-05-03 22:59:48","AP01SDTM":"2020-05-03 04:59:48","AP01EDTM":"2022-05-03 16:59:48","AP02SDTM":"2022-05-03 16:59:48","AP02EDTM":"2023-05-03 22:59:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-03","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5515,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.54731,"AVALU":"mg/L","BASE2":9.90637,"BASE":8.02468,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.64094,"PCHG2":6.46995,"CHG":2.52262,"PCHG":31.43582,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2021-11-27 04:59:48","ADY":573,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-331","SUBJID":"id-331","SITEID":"CAN-4","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.65637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 04:59:48","TRTEDTM":"2023-05-03 22:59:48","TRT01SDTM":"2020-05-03 04:59:48","TRT01EDTM":"2022-05-03 16:59:48","TRT02SDTM":"2022-05-03 16:59:48","TRT02EDTM":"2023-05-03 22:59:48","AP01SDTM":"2020-05-03 04:59:48","AP01EDTM":"2022-05-03 16:59:48","AP02SDTM":"2022-05-03 16:59:48","AP02EDTM":"2023-05-03 22:59:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-03","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4800,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.26552,"AVALU":"mg/L","BASE2":9.90637,"BASE":8.02468,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.35915,"PCHG2":3.62545,"CHG":2.24084,"PCHG":27.92432,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-12-09 04:59:48","ADY":585,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-331","SUBJID":"id-331","SITEID":"CAN-4","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.65637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 04:59:48","TRTEDTM":"2023-05-03 22:59:48","TRT01SDTM":"2020-05-03 04:59:48","TRT01EDTM":"2022-05-03 16:59:48","TRT02SDTM":"2022-05-03 16:59:48","TRT02EDTM":"2023-05-03 22:59:48","AP01SDTM":"2020-05-03 04:59:48","AP01EDTM":"2022-05-03 16:59:48","AP02SDTM":"2022-05-03 16:59:48","AP02EDTM":"2023-05-03 22:59:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-03","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1951,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.34681,"AVALU":"mg/L","BASE2":9.90637,"BASE":8.02468,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.44044,"PCHG2":14.54059,"CHG":3.32213,"PCHG":41.39892,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2021-12-20 04:59:48","ADY":596,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-331","SUBJID":"id-331","SITEID":"CAN-4","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.65637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 04:59:48","TRTEDTM":"2023-05-03 22:59:48","TRT01SDTM":"2020-05-03 04:59:48","TRT01EDTM":"2022-05-03 16:59:48","TRT02SDTM":"2022-05-03 16:59:48","TRT02EDTM":"2023-05-03 22:59:48","AP01SDTM":"2020-05-03 04:59:48","AP01EDTM":"2022-05-03 16:59:48","AP02SDTM":"2022-05-03 16:59:48","AP02EDTM":"2023-05-03 22:59:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-03","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4865,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.06182,"AVALU":"mg/L","BASE2":9.90637,"BASE":8.02468,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.84455,"PCHG2":-8.52531,"CHG":1.03714,"PCHG":12.92435,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-03 04:59:48","ADY":669,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-331","SUBJID":"id-331","SITEID":"CAN-4","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.65637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 04:59:48","TRTEDTM":"2023-05-03 22:59:48","TRT01SDTM":"2020-05-03 04:59:48","TRT01EDTM":"2022-05-03 16:59:48","TRT02SDTM":"2022-05-03 16:59:48","TRT02EDTM":"2023-05-03 22:59:48","AP01SDTM":"2020-05-03 04:59:48","AP01EDTM":"2022-05-03 16:59:48","AP02SDTM":"2022-05-03 16:59:48","AP02EDTM":"2023-05-03 22:59:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-03","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7925,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.42501,"AVALU":"mg/L","BASE2":9.90637,"BASE":8.02468,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.51865,"PCHG2":5.23548,"CHG":2.40033,"PCHG":29.91187,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-12-22 04:59:48","ADY":963,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-331","SUBJID":"id-331","SITEID":"CAN-4","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.65637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 04:59:48","TRTEDTM":"2023-05-03 22:59:48","TRT01SDTM":"2020-05-03 04:59:48","TRT01EDTM":"2022-05-03 16:59:48","TRT02SDTM":"2022-05-03 16:59:48","TRT02EDTM":"2023-05-03 22:59:48","AP01SDTM":"2020-05-03 04:59:48","AP01EDTM":"2022-05-03 16:59:48","AP02SDTM":"2022-05-03 16:59:48","AP02EDTM":"2023-05-03 22:59:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-03","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":520,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74959,"AVALU":"g/L","BASE2":2.74959,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-30 04:59:48","ADY":241,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-331","SUBJID":"id-331","SITEID":"CAN-4","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.65637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 04:59:48","TRTEDTM":"2023-05-03 22:59:48","TRT01SDTM":"2020-05-03 04:59:48","TRT01EDTM":"2022-05-03 16:59:48","TRT02SDTM":"2022-05-03 16:59:48","TRT02EDTM":"2023-05-03 22:59:48","AP01SDTM":"2020-05-03 04:59:48","AP01EDTM":"2022-05-03 16:59:48","AP02SDTM":"2022-05-03 16:59:48","AP02EDTM":"2023-05-03 22:59:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-03","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":741,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75027,"AVALU":"g/L","BASE2":2.74959,"BASE":2.75027,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.00068,"PCHG2":0.0247,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-20 04:59:48","ADY":352,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-331","SUBJID":"id-331","SITEID":"CAN-4","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.65637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 04:59:48","TRTEDTM":"2023-05-03 22:59:48","TRT01SDTM":"2020-05-03 04:59:48","TRT01EDTM":"2022-05-03 16:59:48","TRT02SDTM":"2022-05-03 16:59:48","TRT02EDTM":"2023-05-03 22:59:48","AP01SDTM":"2020-05-03 04:59:48","AP01EDTM":"2022-05-03 16:59:48","AP02SDTM":"2022-05-03 16:59:48","AP02EDTM":"2023-05-03 22:59:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-03","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4342,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86699,"AVALU":"g/L","BASE2":2.74959,"BASE":2.75027,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11739,"PCHG2":4.26948,"CHG":0.11671,"PCHG":4.24373,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-27 04:59:48","ADY":573,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-331","SUBJID":"id-331","SITEID":"CAN-4","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.65637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 04:59:48","TRTEDTM":"2023-05-03 22:59:48","TRT01SDTM":"2020-05-03 04:59:48","TRT01EDTM":"2022-05-03 16:59:48","TRT02SDTM":"2022-05-03 16:59:48","TRT02EDTM":"2023-05-03 22:59:48","AP01SDTM":"2020-05-03 04:59:48","AP01EDTM":"2022-05-03 16:59:48","AP02SDTM":"2022-05-03 16:59:48","AP02EDTM":"2023-05-03 22:59:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-03","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1837,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80741,"AVALU":"g/L","BASE2":2.74959,"BASE":2.75027,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05782,"PCHG2":2.10288,"CHG":0.05714,"PCHG":2.07767,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-09 04:59:48","ADY":585,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-331","SUBJID":"id-331","SITEID":"CAN-4","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.65637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 04:59:48","TRTEDTM":"2023-05-03 22:59:48","TRT01SDTM":"2020-05-03 04:59:48","TRT01EDTM":"2022-05-03 16:59:48","TRT02SDTM":"2022-05-03 16:59:48","TRT02EDTM":"2023-05-03 22:59:48","AP01SDTM":"2020-05-03 04:59:48","AP01EDTM":"2022-05-03 16:59:48","AP02SDTM":"2022-05-03 16:59:48","AP02EDTM":"2023-05-03 22:59:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-03","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1811,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90779,"AVALU":"g/L","BASE2":2.74959,"BASE":2.75027,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15819,"PCHG2":5.75327,"CHG":0.15751,"PCHG":5.72716,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-20 04:59:48","ADY":596,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-331","SUBJID":"id-331","SITEID":"CAN-4","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.65637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 04:59:48","TRTEDTM":"2023-05-03 22:59:48","TRT01SDTM":"2020-05-03 04:59:48","TRT01EDTM":"2022-05-03 16:59:48","TRT02SDTM":"2022-05-03 16:59:48","TRT02EDTM":"2023-05-03 22:59:48","AP01SDTM":"2020-05-03 04:59:48","AP01EDTM":"2022-05-03 16:59:48","AP02SDTM":"2022-05-03 16:59:48","AP02EDTM":"2023-05-03 22:59:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-03","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7976,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83139,"AVALU":"g/L","BASE2":2.74959,"BASE":2.75027,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0818,"PCHG2":2.97489,"CHG":0.08112,"PCHG":2.94947,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-03 04:59:48","ADY":669,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-4-id-331","SUBJID":"id-331","SITEID":"CAN-4","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-4","INVNAM":"Dr. CAN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":3.65637,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 04:59:48","TRTEDTM":"2023-05-03 22:59:48","TRT01SDTM":"2020-05-03 04:59:48","TRT01EDTM":"2022-05-03 16:59:48","TRT02SDTM":"2022-05-03 16:59:48","TRT02EDTM":"2023-05-03 22:59:48","AP01SDTM":"2020-05-03 04:59:48","AP01EDTM":"2022-05-03 16:59:48","AP02SDTM":"2022-05-03 16:59:48","AP02EDTM":"2023-05-03 22:59:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-03","EOSDY":1096,"LSTALVDT":"2023-05-15","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3045,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96033,"AVALU":"g/L","BASE2":2.74959,"BASE":2.75027,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.21074,"PCHG2":7.66437,"CHG":0.21006,"PCHG":7.63779,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-22 04:59:48","ADY":963,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-5-id-121","SUBJID":"id-121","SITEID":"CAN-5","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-5","INVNAM":"Dr. CAN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":8.41726,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-11","TRTSDTM":"2019-10-15 07:06:19","TRT01SDTM":"2019-10-15 07:06:19","AP01SDTM":"2019-10-15 07:06:19","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8199,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.85421,"AVALU":"U/L","BASE2":15.85421,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-17 07:06:19","ADY":63,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-5-id-121","SUBJID":"id-121","SITEID":"CAN-5","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-5","INVNAM":"Dr. CAN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":8.41726,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-11","TRTSDTM":"2019-10-15 07:06:19","TRT01SDTM":"2019-10-15 07:06:19","AP01SDTM":"2019-10-15 07:06:19","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":880,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.41586,"AVALU":"U/L","BASE2":15.85421,"BASE":17.41586,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.56165,"PCHG2":9.85006,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-20 07:06:19","ADY":97,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-5-id-121","SUBJID":"id-121","SITEID":"CAN-5","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-5","INVNAM":"Dr. CAN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":8.41726,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-11","TRTSDTM":"2019-10-15 07:06:19","TRT01SDTM":"2019-10-15 07:06:19","AP01SDTM":"2019-10-15 07:06:19","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1734,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.84313,"AVALU":"U/L","BASE2":15.85421,"BASE":17.41586,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.01107,"PCHG2":-37.9147,"CHG":-7.57272,"PCHG":-43.48178,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-22 07:06:19","ADY":190,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-5-id-121","SUBJID":"id-121","SITEID":"CAN-5","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-5","INVNAM":"Dr. CAN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":8.41726,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-11","TRTSDTM":"2019-10-15 07:06:19","TRT01SDTM":"2019-10-15 07:06:19","AP01SDTM":"2019-10-15 07:06:19","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4972,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.49329,"AVALU":"U/L","BASE2":15.85421,"BASE":17.41586,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.63908,"PCHG2":54.49078,"CHG":7.07743,"PCHG":40.63786,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-11 07:06:19","ADY":209,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-5-id-121","SUBJID":"id-121","SITEID":"CAN-5","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-5","INVNAM":"Dr. CAN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":8.41726,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-11","TRTSDTM":"2019-10-15 07:06:19","TRT01SDTM":"2019-10-15 07:06:19","AP01SDTM":"2019-10-15 07:06:19","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4897,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.80645,"AVALU":"U/L","BASE2":15.85421,"BASE":17.41586,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.95224,"PCHG2":18.6212,"CHG":1.39059,"PCHG":7.98464,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-04 07:06:19","ADY":294,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-5-id-121","SUBJID":"id-121","SITEID":"CAN-5","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-5","INVNAM":"Dr. CAN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":8.41726,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-11","TRTSDTM":"2019-10-15 07:06:19","TRT01SDTM":"2019-10-15 07:06:19","AP01SDTM":"2019-10-15 07:06:19","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":764,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.8718,"AVALU":"U/L","BASE2":15.85421,"BASE":17.41586,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0176,"PCHG2":0.11098,"CHG":-1.54405,"PCHG":-8.8658,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-22 07:06:19","ADY":343,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-5-id-121","SUBJID":"id-121","SITEID":"CAN-5","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-5","INVNAM":"Dr. CAN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":8.41726,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-11","TRTSDTM":"2019-10-15 07:06:19","TRT01SDTM":"2019-10-15 07:06:19","AP01SDTM":"2019-10-15 07:06:19","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4122,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.563,"AVALU":"U/L","BASE2":15.85421,"BASE":17.41586,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.7088,"PCHG2":86.46788,"CHG":12.14715,"PCHG":69.74763,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-18 07:06:19","ADY":369,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-5-id-121","SUBJID":"id-121","SITEID":"CAN-5","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-5","INVNAM":"Dr. CAN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":8.41726,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-11","TRTSDTM":"2019-10-15 07:06:19","TRT01SDTM":"2019-10-15 07:06:19","AP01SDTM":"2019-10-15 07:06:19","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4033,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.02889,"AVALU":"mg/L","BASE2":10.02889,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"3","ADTM":"2019-12-17 07:06:19","ADY":63,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-5-id-121","SUBJID":"id-121","SITEID":"CAN-5","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-5","INVNAM":"Dr. CAN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":8.41726,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-11","TRTSDTM":"2019-10-15 07:06:19","TRT01SDTM":"2019-10-15 07:06:19","AP01SDTM":"2019-10-15 07:06:19","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3005,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.16373,"AVALU":"mg/L","BASE2":10.02889,"BASE":10.16373,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.13484,"PCHG2":1.34449,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2020-01-20 07:06:19","ADY":97,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-5-id-121","SUBJID":"id-121","SITEID":"CAN-5","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-5","INVNAM":"Dr. CAN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":8.41726,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-11","TRTSDTM":"2019-10-15 07:06:19","TRT01SDTM":"2019-10-15 07:06:19","AP01SDTM":"2019-10-15 07:06:19","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8134,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.60902,"AVALU":"mg/L","BASE2":10.02889,"BASE":10.16373,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.58013,"PCHG2":5.78462,"CHG":0.4453,"PCHG":4.38123,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"1","BTOXGR":"3","ADTM":"2020-04-22 07:06:19","ADY":190,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-5-id-121","SUBJID":"id-121","SITEID":"CAN-5","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-5","INVNAM":"Dr. CAN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":8.41726,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-11","TRTSDTM":"2019-10-15 07:06:19","TRT01SDTM":"2019-10-15 07:06:19","AP01SDTM":"2019-10-15 07:06:19","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":901,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.11576,"AVALU":"mg/L","BASE2":10.02889,"BASE":10.16373,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.91313,"PCHG2":-9.10502,"CHG":-1.04797,"PCHG":-10.31088,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-05-11 07:06:19","ADY":209,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-5-id-121","SUBJID":"id-121","SITEID":"CAN-5","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-5","INVNAM":"Dr. CAN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":8.41726,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-11","TRTSDTM":"2019-10-15 07:06:19","TRT01SDTM":"2019-10-15 07:06:19","AP01SDTM":"2019-10-15 07:06:19","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1176,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.08422,"AVALU":"mg/L","BASE2":10.02889,"BASE":10.16373,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.94467,"PCHG2":-9.41952,"CHG":-1.07951,"PCHG":-10.62121,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-08-04 07:06:19","ADY":294,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-5-id-121","SUBJID":"id-121","SITEID":"CAN-5","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-5","INVNAM":"Dr. CAN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":8.41726,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-11","TRTSDTM":"2019-10-15 07:06:19","TRT01SDTM":"2019-10-15 07:06:19","AP01SDTM":"2019-10-15 07:06:19","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4627,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.26962,"AVALU":"mg/L","BASE2":10.02889,"BASE":10.16373,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.75927,"PCHG2":-7.57087,"CHG":-0.89411,"PCHG":-8.79708,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-09-22 07:06:19","ADY":343,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-5-id-121","SUBJID":"id-121","SITEID":"CAN-5","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-5","INVNAM":"Dr. CAN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":8.41726,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-11","TRTSDTM":"2019-10-15 07:06:19","TRT01SDTM":"2019-10-15 07:06:19","AP01SDTM":"2019-10-15 07:06:19","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1006,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.45262,"AVALU":"mg/L","BASE2":10.02889,"BASE":10.16373,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.57627,"PCHG2":-5.74611,"CHG":-0.71111,"PCHG":-6.99653,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-10-18 07:06:19","ADY":369,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-5-id-121","SUBJID":"id-121","SITEID":"CAN-5","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-5","INVNAM":"Dr. CAN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":8.41726,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-11","TRTSDTM":"2019-10-15 07:06:19","TRT01SDTM":"2019-10-15 07:06:19","AP01SDTM":"2019-10-15 07:06:19","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6117,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.68377,"AVALU":"g/L","BASE2":2.68377,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-17 07:06:19","ADY":63,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-5-id-121","SUBJID":"id-121","SITEID":"CAN-5","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-5","INVNAM":"Dr. CAN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":8.41726,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-11","TRTSDTM":"2019-10-15 07:06:19","TRT01SDTM":"2019-10-15 07:06:19","AP01SDTM":"2019-10-15 07:06:19","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6657,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93375,"AVALU":"g/L","BASE2":2.68377,"BASE":2.93375,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.24998,"PCHG2":9.31457,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-20 07:06:19","ADY":97,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-5-id-121","SUBJID":"id-121","SITEID":"CAN-5","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-5","INVNAM":"Dr. CAN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":8.41726,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-11","TRTSDTM":"2019-10-15 07:06:19","TRT01SDTM":"2019-10-15 07:06:19","AP01SDTM":"2019-10-15 07:06:19","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4875,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97088,"AVALU":"g/L","BASE2":2.68377,"BASE":2.93375,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.2871,"PCHG2":10.69778,"CHG":0.03712,"PCHG":1.26535,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-22 07:06:19","ADY":190,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-5-id-121","SUBJID":"id-121","SITEID":"CAN-5","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-5","INVNAM":"Dr. CAN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":8.41726,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-11","TRTSDTM":"2019-10-15 07:06:19","TRT01SDTM":"2019-10-15 07:06:19","AP01SDTM":"2019-10-15 07:06:19","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5818,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96493,"AVALU":"g/L","BASE2":2.68377,"BASE":2.93375,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.28116,"PCHG2":10.47618,"CHG":0.03118,"PCHG":1.06263,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-11 07:06:19","ADY":209,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-5-id-121","SUBJID":"id-121","SITEID":"CAN-5","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-5","INVNAM":"Dr. CAN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":8.41726,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-11","TRTSDTM":"2019-10-15 07:06:19","TRT01SDTM":"2019-10-15 07:06:19","AP01SDTM":"2019-10-15 07:06:19","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6335,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98359,"AVALU":"g/L","BASE2":2.68377,"BASE":2.93375,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.29982,"PCHG2":11.17155,"CHG":0.04984,"PCHG":1.69875,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-04 07:06:19","ADY":294,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-5-id-121","SUBJID":"id-121","SITEID":"CAN-5","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-5","INVNAM":"Dr. CAN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":8.41726,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-11","TRTSDTM":"2019-10-15 07:06:19","TRT01SDTM":"2019-10-15 07:06:19","AP01SDTM":"2019-10-15 07:06:19","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5883,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99861,"AVALU":"g/L","BASE2":2.68377,"BASE":2.93375,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.31484,"PCHG2":11.73111,"CHG":0.06485,"PCHG":2.21063,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-22 07:06:19","ADY":343,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CAN-5-id-121","SUBJID":"id-121","SITEID":"CAN-5","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CAN","DTHFL":"N","INVID":"INV ID CAN-5","INVNAM":"Dr. CAN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":8.41726,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-11","TRTSDTM":"2019-10-15 07:06:19","TRT01SDTM":"2019-10-15 07:06:19","AP01SDTM":"2019-10-15 07:06:19","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3867,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86647,"AVALU":"g/L","BASE2":2.68377,"BASE":2.93375,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1827,"PCHG2":6.80748,"CHG":-0.06728,"PCHG":-2.29346,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-18 07:06:19","ADY":369,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-107","SUBJID":"id-107","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.02114,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-07-31 01:51:06","TRTEDTM":"2022-02-19 21:20:15","TRT01SDTM":"2020-07-31 01:51:06","TRT01EDTM":"2021-02-19 15:20:15","TRT02SDTM":"2021-02-19 15:20:15","TRT02EDTM":"2022-02-19 21:20:15","AP01SDTM":"2020-07-31 01:51:06","AP01EDTM":"2021-02-19 15:20:15","AP02SDTM":"2021-02-19 15:20:15","AP02EDTM":"2022-02-19 21:20:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":569,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4277,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.45185,"AVALU":"U/L","BASE2":27.45185,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-06 01:51:06","ADY":6,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-107","SUBJID":"id-107","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.02114,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-07-31 01:51:06","TRTEDTM":"2022-02-19 21:20:15","TRT01SDTM":"2020-07-31 01:51:06","TRT01EDTM":"2021-02-19 15:20:15","TRT02SDTM":"2021-02-19 15:20:15","TRT02EDTM":"2022-02-19 21:20:15","AP01SDTM":"2020-07-31 01:51:06","AP01EDTM":"2021-02-19 15:20:15","AP02SDTM":"2021-02-19 15:20:15","AP02EDTM":"2022-02-19 21:20:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":569,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2887,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.32172,"AVALU":"U/L","BASE2":27.45185,"BASE":19.32172,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-8.13013,"PCHG2":-29.61597,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-17 01:51:06","ADY":109,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-107","SUBJID":"id-107","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.02114,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-07-31 01:51:06","TRTEDTM":"2022-02-19 21:20:15","TRT01SDTM":"2020-07-31 01:51:06","TRT01EDTM":"2021-02-19 15:20:15","TRT02SDTM":"2021-02-19 15:20:15","TRT02EDTM":"2022-02-19 21:20:15","AP01SDTM":"2020-07-31 01:51:06","AP01EDTM":"2021-02-19 15:20:15","AP02SDTM":"2021-02-19 15:20:15","AP02EDTM":"2022-02-19 21:20:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":569,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4120,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.94222,"AVALU":"U/L","BASE2":27.45185,"BASE":19.32172,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.49038,"PCHG2":23.64276,"CHG":14.62051,"PCHG":75.66878,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-28 01:51:06","ADY":240,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-107","SUBJID":"id-107","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.02114,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-07-31 01:51:06","TRTEDTM":"2022-02-19 21:20:15","TRT01SDTM":"2020-07-31 01:51:06","TRT01EDTM":"2021-02-19 15:20:15","TRT02SDTM":"2021-02-19 15:20:15","TRT02EDTM":"2022-02-19 21:20:15","AP01SDTM":"2020-07-31 01:51:06","AP01EDTM":"2021-02-19 15:20:15","AP02SDTM":"2021-02-19 15:20:15","AP02EDTM":"2022-02-19 21:20:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":569,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3696,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.21996,"AVALU":"U/L","BASE2":27.45185,"BASE":19.32172,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-22.23189,"PCHG2":-80.98503,"CHG":-14.10176,"PCHG":-72.98397,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-05-03 01:51:06","ADY":276,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-107","SUBJID":"id-107","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.02114,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-07-31 01:51:06","TRTEDTM":"2022-02-19 21:20:15","TRT01SDTM":"2020-07-31 01:51:06","TRT01EDTM":"2021-02-19 15:20:15","TRT02SDTM":"2021-02-19 15:20:15","TRT02EDTM":"2022-02-19 21:20:15","AP01SDTM":"2020-07-31 01:51:06","AP01EDTM":"2021-02-19 15:20:15","AP02SDTM":"2021-02-19 15:20:15","AP02EDTM":"2022-02-19 21:20:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":569,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3513,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.77267,"AVALU":"U/L","BASE2":27.45185,"BASE":19.32172,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-21.67918,"PCHG2":-78.97165,"CHG":-13.54905,"PCHG":-70.12341,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-07-08 01:51:06","ADY":342,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-107","SUBJID":"id-107","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.02114,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-07-31 01:51:06","TRTEDTM":"2022-02-19 21:20:15","TRT01SDTM":"2020-07-31 01:51:06","TRT01EDTM":"2021-02-19 15:20:15","TRT02SDTM":"2021-02-19 15:20:15","TRT02EDTM":"2022-02-19 21:20:15","AP01SDTM":"2020-07-31 01:51:06","AP01EDTM":"2021-02-19 15:20:15","AP02SDTM":"2021-02-19 15:20:15","AP02EDTM":"2022-02-19 21:20:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":569,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":478,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.12612,"AVALU":"U/L","BASE2":27.45185,"BASE":19.32172,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.32573,"PCHG2":-59.47043,"CHG":-8.1956,"PCHG":-42.41653,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-24 01:51:06","ADY":420,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-107","SUBJID":"id-107","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.02114,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-07-31 01:51:06","TRTEDTM":"2022-02-19 21:20:15","TRT01SDTM":"2020-07-31 01:51:06","TRT01EDTM":"2021-02-19 15:20:15","TRT02SDTM":"2021-02-19 15:20:15","TRT02EDTM":"2022-02-19 21:20:15","AP01SDTM":"2020-07-31 01:51:06","AP01EDTM":"2021-02-19 15:20:15","AP02SDTM":"2021-02-19 15:20:15","AP02EDTM":"2022-02-19 21:20:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":569,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":230,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.67752,"AVALU":"U/L","BASE2":27.45185,"BASE":19.32172,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.77433,"PCHG2":-53.81905,"CHG":-6.64419,"PCHG":-34.38718,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-16 01:51:06","ADY":442,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-107","SUBJID":"id-107","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.02114,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-07-31 01:51:06","TRTEDTM":"2022-02-19 21:20:15","TRT01SDTM":"2020-07-31 01:51:06","TRT01EDTM":"2021-02-19 15:20:15","TRT02SDTM":"2021-02-19 15:20:15","TRT02EDTM":"2022-02-19 21:20:15","AP01SDTM":"2020-07-31 01:51:06","AP01EDTM":"2021-02-19 15:20:15","AP02SDTM":"2021-02-19 15:20:15","AP02EDTM":"2022-02-19 21:20:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":569,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2974,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.39967,"AVALU":"mg/L","BASE2":8.39967,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-08-06 01:51:06","ADY":6,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-107","SUBJID":"id-107","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.02114,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-07-31 01:51:06","TRTEDTM":"2022-02-19 21:20:15","TRT01SDTM":"2020-07-31 01:51:06","TRT01EDTM":"2021-02-19 15:20:15","TRT02SDTM":"2021-02-19 15:20:15","TRT02EDTM":"2022-02-19 21:20:15","AP01SDTM":"2020-07-31 01:51:06","AP01EDTM":"2021-02-19 15:20:15","AP02SDTM":"2021-02-19 15:20:15","AP02EDTM":"2022-02-19 21:20:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":569,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4784,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.69592,"AVALU":"mg/L","BASE2":8.39967,"BASE":6.69592,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.70375,"PCHG2":-20.28355,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2020-11-17 01:51:06","ADY":109,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-107","SUBJID":"id-107","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.02114,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-07-31 01:51:06","TRTEDTM":"2022-02-19 21:20:15","TRT01SDTM":"2020-07-31 01:51:06","TRT01EDTM":"2021-02-19 15:20:15","TRT02SDTM":"2021-02-19 15:20:15","TRT02EDTM":"2022-02-19 21:20:15","AP01SDTM":"2020-07-31 01:51:06","AP01EDTM":"2021-02-19 15:20:15","AP02SDTM":"2021-02-19 15:20:15","AP02EDTM":"2022-02-19 21:20:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":569,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3744,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.51409,"AVALU":"mg/L","BASE2":8.39967,"BASE":6.69592,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.11442,"PCHG2":25.17261,"CHG":3.81817,"PCHG":57.02231,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"1","BTOXGR":"-1","ADTM":"2021-03-28 01:51:06","ADY":240,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-107","SUBJID":"id-107","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.02114,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-07-31 01:51:06","TRTEDTM":"2022-02-19 21:20:15","TRT01SDTM":"2020-07-31 01:51:06","TRT01EDTM":"2021-02-19 15:20:15","TRT02SDTM":"2021-02-19 15:20:15","TRT02EDTM":"2022-02-19 21:20:15","AP01SDTM":"2020-07-31 01:51:06","AP01EDTM":"2021-02-19 15:20:15","AP02SDTM":"2021-02-19 15:20:15","AP02EDTM":"2022-02-19 21:20:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":569,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6306,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.95461,"AVALU":"mg/L","BASE2":8.39967,"BASE":6.69592,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.55494,"PCHG2":18.51186,"CHG":3.25869,"PCHG":48.66676,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-05-03 01:51:06","ADY":276,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-107","SUBJID":"id-107","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.02114,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-07-31 01:51:06","TRTEDTM":"2022-02-19 21:20:15","TRT01SDTM":"2020-07-31 01:51:06","TRT01EDTM":"2021-02-19 15:20:15","TRT02SDTM":"2021-02-19 15:20:15","TRT02EDTM":"2022-02-19 21:20:15","AP01SDTM":"2020-07-31 01:51:06","AP01EDTM":"2021-02-19 15:20:15","AP02SDTM":"2021-02-19 15:20:15","AP02EDTM":"2022-02-19 21:20:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":569,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7590,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.4994,"AVALU":"mg/L","BASE2":8.39967,"BASE":6.69592,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.09973,"PCHG2":24.9977,"CHG":3.80348,"PCHG":56.8029,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"4","BTOXGR":"-1","ADTM":"2021-07-08 01:51:06","ADY":342,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-107","SUBJID":"id-107","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.02114,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-07-31 01:51:06","TRTEDTM":"2022-02-19 21:20:15","TRT01SDTM":"2020-07-31 01:51:06","TRT01EDTM":"2021-02-19 15:20:15","TRT02SDTM":"2021-02-19 15:20:15","TRT02EDTM":"2022-02-19 21:20:15","AP01SDTM":"2020-07-31 01:51:06","AP01EDTM":"2021-02-19 15:20:15","AP02SDTM":"2021-02-19 15:20:15","AP02EDTM":"2022-02-19 21:20:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":569,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5056,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.15363,"AVALU":"mg/L","BASE2":8.39967,"BASE":6.69592,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.24605,"PCHG2":-14.8345,"CHG":0.4577,"PCHG":6.83554,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-3","BTOXGR":"-1","ADTM":"2021-09-24 01:51:06","ADY":420,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-107","SUBJID":"id-107","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.02114,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-07-31 01:51:06","TRTEDTM":"2022-02-19 21:20:15","TRT01SDTM":"2020-07-31 01:51:06","TRT01EDTM":"2021-02-19 15:20:15","TRT02SDTM":"2021-02-19 15:20:15","TRT02EDTM":"2022-02-19 21:20:15","AP01SDTM":"2020-07-31 01:51:06","AP01EDTM":"2021-02-19 15:20:15","AP02SDTM":"2021-02-19 15:20:15","AP02EDTM":"2022-02-19 21:20:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":569,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6768,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.36131,"AVALU":"mg/L","BASE2":8.39967,"BASE":6.69592,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.03837,"PCHG2":-12.362,"CHG":0.66538,"PCHG":9.93717,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2021-10-16 01:51:06","ADY":442,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-107","SUBJID":"id-107","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.02114,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-07-31 01:51:06","TRTEDTM":"2022-02-19 21:20:15","TRT01SDTM":"2020-07-31 01:51:06","TRT01EDTM":"2021-02-19 15:20:15","TRT02SDTM":"2021-02-19 15:20:15","TRT02EDTM":"2022-02-19 21:20:15","AP01SDTM":"2020-07-31 01:51:06","AP01EDTM":"2021-02-19 15:20:15","AP02SDTM":"2021-02-19 15:20:15","AP02EDTM":"2022-02-19 21:20:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":569,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8006,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95441,"AVALU":"g/L","BASE2":2.95441,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-06 01:51:06","ADY":6,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-107","SUBJID":"id-107","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.02114,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-07-31 01:51:06","TRTEDTM":"2022-02-19 21:20:15","TRT01SDTM":"2020-07-31 01:51:06","TRT01EDTM":"2021-02-19 15:20:15","TRT02SDTM":"2021-02-19 15:20:15","TRT02EDTM":"2022-02-19 21:20:15","AP01SDTM":"2020-07-31 01:51:06","AP01EDTM":"2021-02-19 15:20:15","AP02SDTM":"2021-02-19 15:20:15","AP02EDTM":"2022-02-19 21:20:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":569,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2931,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99923,"AVALU":"g/L","BASE2":2.95441,"BASE":2.99923,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.04481,"PCHG2":1.51686,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-17 01:51:06","ADY":109,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-107","SUBJID":"id-107","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.02114,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-07-31 01:51:06","TRTEDTM":"2022-02-19 21:20:15","TRT01SDTM":"2020-07-31 01:51:06","TRT01EDTM":"2021-02-19 15:20:15","TRT02SDTM":"2021-02-19 15:20:15","TRT02EDTM":"2022-02-19 21:20:15","AP01SDTM":"2020-07-31 01:51:06","AP01EDTM":"2021-02-19 15:20:15","AP02SDTM":"2021-02-19 15:20:15","AP02EDTM":"2022-02-19 21:20:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":569,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1125,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94698,"AVALU":"g/L","BASE2":2.95441,"BASE":2.99923,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00743,"PCHG2":-0.25155,"CHG":-0.05225,"PCHG":-1.74199,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-28 01:51:06","ADY":240,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-107","SUBJID":"id-107","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.02114,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-07-31 01:51:06","TRTEDTM":"2022-02-19 21:20:15","TRT01SDTM":"2020-07-31 01:51:06","TRT01EDTM":"2021-02-19 15:20:15","TRT02SDTM":"2021-02-19 15:20:15","TRT02EDTM":"2022-02-19 21:20:15","AP01SDTM":"2020-07-31 01:51:06","AP01EDTM":"2021-02-19 15:20:15","AP02SDTM":"2021-02-19 15:20:15","AP02EDTM":"2022-02-19 21:20:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":569,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8139,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87867,"AVALU":"g/L","BASE2":2.95441,"BASE":2.99923,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07575,"PCHG2":-2.56387,"CHG":-0.12056,"PCHG":-4.01975,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-03 01:51:06","ADY":276,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-107","SUBJID":"id-107","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.02114,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-07-31 01:51:06","TRTEDTM":"2022-02-19 21:20:15","TRT01SDTM":"2020-07-31 01:51:06","TRT01EDTM":"2021-02-19 15:20:15","TRT02SDTM":"2021-02-19 15:20:15","TRT02EDTM":"2022-02-19 21:20:15","AP01SDTM":"2020-07-31 01:51:06","AP01EDTM":"2021-02-19 15:20:15","AP02SDTM":"2021-02-19 15:20:15","AP02EDTM":"2022-02-19 21:20:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":569,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6785,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00065,"AVALU":"g/L","BASE2":2.95441,"BASE":2.99923,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04624,"PCHG2":1.56506,"CHG":0.00142,"PCHG":0.04748,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-07-08 01:51:06","ADY":342,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-107","SUBJID":"id-107","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.02114,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-07-31 01:51:06","TRTEDTM":"2022-02-19 21:20:15","TRT01SDTM":"2020-07-31 01:51:06","TRT01EDTM":"2021-02-19 15:20:15","TRT02SDTM":"2021-02-19 15:20:15","TRT02EDTM":"2022-02-19 21:20:15","AP01SDTM":"2020-07-31 01:51:06","AP01EDTM":"2021-02-19 15:20:15","AP02SDTM":"2021-02-19 15:20:15","AP02EDTM":"2022-02-19 21:20:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":569,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8235,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88421,"AVALU":"g/L","BASE2":2.95441,"BASE":2.99923,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07021,"PCHG2":-2.37629,"CHG":-0.11502,"PCHG":-3.83498,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-24 01:51:06","ADY":420,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-107","SUBJID":"id-107","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.02114,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-07-31 01:51:06","TRTEDTM":"2022-02-19 21:20:15","TRT01SDTM":"2020-07-31 01:51:06","TRT01EDTM":"2021-02-19 15:20:15","TRT02SDTM":"2021-02-19 15:20:15","TRT02EDTM":"2022-02-19 21:20:15","AP01SDTM":"2020-07-31 01:51:06","AP01EDTM":"2021-02-19 15:20:15","AP02SDTM":"2021-02-19 15:20:15","AP02EDTM":"2022-02-19 21:20:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":569,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":670,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0275,"AVALU":"g/L","BASE2":2.95441,"BASE":2.99923,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07308,"PCHG2":2.47369,"CHG":0.02827,"PCHG":0.94254,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-10-16 01:51:06","ADY":442,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-119","SUBJID":"id-119","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":8.61739,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-14 00:58:47","TRTEDTM":"2022-02-15 20:00:07","TRT01SDTM":"2020-01-14 00:58:47","TRT01EDTM":"2021-02-15 14:00:07","TRT02SDTM":"2021-02-15 14:00:07","TRT02EDTM":"2022-02-15 20:00:07","AP01SDTM":"2020-01-14 00:58:47","AP01EDTM":"2021-02-15 14:00:07","AP02SDTM":"2021-02-15 14:00:07","AP02EDTM":"2022-02-15 20:00:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":764,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-16","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":938,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":38.75245,"AVALU":"U/L","BASE2":38.75245,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-31 00:58:47","ADY":17,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-119","SUBJID":"id-119","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":8.61739,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-14 00:58:47","TRTEDTM":"2022-02-15 20:00:07","TRT01SDTM":"2020-01-14 00:58:47","TRT01EDTM":"2021-02-15 14:00:07","TRT02SDTM":"2021-02-15 14:00:07","TRT02EDTM":"2022-02-15 20:00:07","AP01SDTM":"2020-01-14 00:58:47","AP01EDTM":"2021-02-15 14:00:07","AP02SDTM":"2021-02-15 14:00:07","AP02EDTM":"2022-02-15 20:00:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":764,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-16","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7929,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.23447,"AVALU":"U/L","BASE2":38.75245,"BASE":17.23447,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-21.51798,"PCHG2":-55.52675,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-25 00:58:47","ADY":102,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-119","SUBJID":"id-119","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":8.61739,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-14 00:58:47","TRTEDTM":"2022-02-15 20:00:07","TRT01SDTM":"2020-01-14 00:58:47","TRT01EDTM":"2021-02-15 14:00:07","TRT02SDTM":"2021-02-15 14:00:07","TRT02EDTM":"2022-02-15 20:00:07","AP01SDTM":"2020-01-14 00:58:47","AP01EDTM":"2021-02-15 14:00:07","AP02SDTM":"2021-02-15 14:00:07","AP02EDTM":"2022-02-15 20:00:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":764,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-16","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2453,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.86712,"AVALU":"U/L","BASE2":38.75245,"BASE":17.23447,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-28.88533,"PCHG2":-74.53807,"CHG":-7.36735,"PCHG":-42.74776,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-21 00:58:47","ADY":251,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-119","SUBJID":"id-119","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":8.61739,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-14 00:58:47","TRTEDTM":"2022-02-15 20:00:07","TRT01SDTM":"2020-01-14 00:58:47","TRT01EDTM":"2021-02-15 14:00:07","TRT02SDTM":"2021-02-15 14:00:07","TRT02EDTM":"2022-02-15 20:00:07","AP01SDTM":"2020-01-14 00:58:47","AP01EDTM":"2021-02-15 14:00:07","AP02SDTM":"2021-02-15 14:00:07","AP02EDTM":"2022-02-15 20:00:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":764,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-16","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1068,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.71943,"AVALU":"U/L","BASE2":38.75245,"BASE":17.23447,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.03302,"PCHG2":-12.98761,"CHG":16.48496,"PCHG":95.65108,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-13 00:58:47","ADY":424,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-119","SUBJID":"id-119","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":8.61739,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-14 00:58:47","TRTEDTM":"2022-02-15 20:00:07","TRT01SDTM":"2020-01-14 00:58:47","TRT01EDTM":"2021-02-15 14:00:07","TRT02SDTM":"2021-02-15 14:00:07","TRT02EDTM":"2022-02-15 20:00:07","AP01SDTM":"2020-01-14 00:58:47","AP01EDTM":"2021-02-15 14:00:07","AP02SDTM":"2021-02-15 14:00:07","AP02EDTM":"2022-02-15 20:00:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":764,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-16","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":668,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.49618,"AVALU":"U/L","BASE2":38.75245,"BASE":17.23447,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.25627,"PCHG2":-44.5295,"CHG":4.26171,"PCHG":24.7278,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-20 00:58:47","ADY":553,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-119","SUBJID":"id-119","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":8.61739,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-14 00:58:47","TRTEDTM":"2022-02-15 20:00:07","TRT01SDTM":"2020-01-14 00:58:47","TRT01EDTM":"2021-02-15 14:00:07","TRT02SDTM":"2021-02-15 14:00:07","TRT02EDTM":"2022-02-15 20:00:07","AP01SDTM":"2020-01-14 00:58:47","AP01EDTM":"2021-02-15 14:00:07","AP02SDTM":"2021-02-15 14:00:07","AP02EDTM":"2022-02-15 20:00:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":764,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-16","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":188,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.0302,"AVALU":"U/L","BASE2":38.75245,"BASE":17.23447,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-21.72225,"PCHG2":-56.05388,"CHG":-0.20428,"PCHG":-1.18527,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-17 00:58:47","ADY":673,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-119","SUBJID":"id-119","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":8.61739,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-14 00:58:47","TRTEDTM":"2022-02-15 20:00:07","TRT01SDTM":"2020-01-14 00:58:47","TRT01EDTM":"2021-02-15 14:00:07","TRT02SDTM":"2021-02-15 14:00:07","TRT02EDTM":"2022-02-15 20:00:07","AP01SDTM":"2020-01-14 00:58:47","AP01EDTM":"2021-02-15 14:00:07","AP02SDTM":"2021-02-15 14:00:07","AP02EDTM":"2022-02-15 20:00:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":764,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-16","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3789,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.20625,"AVALU":"U/L","BASE2":38.75245,"BASE":17.23447,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-21.5462,"PCHG2":-55.59957,"CHG":-0.02822,"PCHG":-0.16373,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-02 00:58:47","ADY":719,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-119","SUBJID":"id-119","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":8.61739,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-14 00:58:47","TRTEDTM":"2022-02-15 20:00:07","TRT01SDTM":"2020-01-14 00:58:47","TRT01EDTM":"2021-02-15 14:00:07","TRT02SDTM":"2021-02-15 14:00:07","TRT02EDTM":"2022-02-15 20:00:07","AP01SDTM":"2020-01-14 00:58:47","AP01EDTM":"2021-02-15 14:00:07","AP02SDTM":"2021-02-15 14:00:07","AP02EDTM":"2022-02-15 20:00:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":764,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-16","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3154,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.34968,"AVALU":"mg/L","BASE2":8.34968,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-3","ADTM":"2020-01-31 00:58:47","ADY":17,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-119","SUBJID":"id-119","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":8.61739,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-14 00:58:47","TRTEDTM":"2022-02-15 20:00:07","TRT01SDTM":"2020-01-14 00:58:47","TRT01EDTM":"2021-02-15 14:00:07","TRT02SDTM":"2021-02-15 14:00:07","TRT02EDTM":"2022-02-15 20:00:07","AP01SDTM":"2020-01-14 00:58:47","AP01EDTM":"2021-02-15 14:00:07","AP02SDTM":"2021-02-15 14:00:07","AP02EDTM":"2022-02-15 20:00:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":764,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-16","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7866,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.94733,"AVALU":"mg/L","BASE2":8.34968,"BASE":7.94733,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.40235,"PCHG2":-4.81873,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2020-04-25 00:58:47","ADY":102,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-119","SUBJID":"id-119","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":8.61739,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-14 00:58:47","TRTEDTM":"2022-02-15 20:00:07","TRT01SDTM":"2020-01-14 00:58:47","TRT01EDTM":"2021-02-15 14:00:07","TRT02SDTM":"2021-02-15 14:00:07","TRT02EDTM":"2022-02-15 20:00:07","AP01SDTM":"2020-01-14 00:58:47","AP01EDTM":"2021-02-15 14:00:07","AP02SDTM":"2021-02-15 14:00:07","AP02EDTM":"2022-02-15 20:00:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":764,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-16","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1633,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.78866,"AVALU":"mg/L","BASE2":8.34968,"BASE":7.94733,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.56102,"PCHG2":-6.71907,"CHG":-0.15867,"PCHG":-1.99655,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-3","ADTM":"2020-09-21 00:58:47","ADY":251,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-119","SUBJID":"id-119","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":8.61739,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-14 00:58:47","TRTEDTM":"2022-02-15 20:00:07","TRT01SDTM":"2020-01-14 00:58:47","TRT01EDTM":"2021-02-15 14:00:07","TRT02SDTM":"2021-02-15 14:00:07","TRT02EDTM":"2022-02-15 20:00:07","AP01SDTM":"2020-01-14 00:58:47","AP01EDTM":"2021-02-15 14:00:07","AP02SDTM":"2021-02-15 14:00:07","AP02EDTM":"2022-02-15 20:00:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":764,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-16","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6693,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.38286,"AVALU":"mg/L","BASE2":8.34968,"BASE":7.94733,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03318,"PCHG2":0.39739,"CHG":0.43553,"PCHG":5.48019,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-03-13 00:58:47","ADY":424,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-119","SUBJID":"id-119","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":8.61739,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-14 00:58:47","TRTEDTM":"2022-02-15 20:00:07","TRT01SDTM":"2020-01-14 00:58:47","TRT01EDTM":"2021-02-15 14:00:07","TRT02SDTM":"2021-02-15 14:00:07","TRT02EDTM":"2022-02-15 20:00:07","AP01SDTM":"2020-01-14 00:58:47","AP01EDTM":"2021-02-15 14:00:07","AP02SDTM":"2021-02-15 14:00:07","AP02EDTM":"2022-02-15 20:00:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":764,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-16","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6825,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.38465,"AVALU":"mg/L","BASE2":8.34968,"BASE":7.94733,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.03496,"PCHG2":12.39523,"CHG":1.43731,"PCHG":18.08545,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-07-20 00:58:47","ADY":553,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-119","SUBJID":"id-119","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":8.61739,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-14 00:58:47","TRTEDTM":"2022-02-15 20:00:07","TRT01SDTM":"2020-01-14 00:58:47","TRT01EDTM":"2021-02-15 14:00:07","TRT02SDTM":"2021-02-15 14:00:07","TRT02EDTM":"2022-02-15 20:00:07","AP01SDTM":"2020-01-14 00:58:47","AP01EDTM":"2021-02-15 14:00:07","AP02SDTM":"2021-02-15 14:00:07","AP02EDTM":"2022-02-15 20:00:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":764,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-16","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8027,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.6361,"AVALU":"mg/L","BASE2":8.34968,"BASE":7.94733,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.71359,"PCHG2":-8.54628,"CHG":-0.31124,"PCHG":-3.91626,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2021-11-17 00:58:47","ADY":673,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-119","SUBJID":"id-119","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":8.61739,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-14 00:58:47","TRTEDTM":"2022-02-15 20:00:07","TRT01SDTM":"2020-01-14 00:58:47","TRT01EDTM":"2021-02-15 14:00:07","TRT02SDTM":"2021-02-15 14:00:07","TRT02EDTM":"2022-02-15 20:00:07","AP01SDTM":"2020-01-14 00:58:47","AP01EDTM":"2021-02-15 14:00:07","AP02SDTM":"2021-02-15 14:00:07","AP02EDTM":"2022-02-15 20:00:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":764,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-16","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5112,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.96785,"AVALU":"mg/L","BASE2":8.34968,"BASE":7.94733,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.61816,"PCHG2":19.37994,"CHG":2.02051,"PCHG":25.42377,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2022-01-02 00:58:47","ADY":719,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-119","SUBJID":"id-119","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":8.61739,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-14 00:58:47","TRTEDTM":"2022-02-15 20:00:07","TRT01SDTM":"2020-01-14 00:58:47","TRT01EDTM":"2021-02-15 14:00:07","TRT02SDTM":"2021-02-15 14:00:07","TRT02EDTM":"2022-02-15 20:00:07","AP01SDTM":"2020-01-14 00:58:47","AP01EDTM":"2021-02-15 14:00:07","AP02SDTM":"2021-02-15 14:00:07","AP02EDTM":"2022-02-15 20:00:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":764,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-16","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":606,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88044,"AVALU":"g/L","BASE2":2.88044,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-31 00:58:47","ADY":17,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-119","SUBJID":"id-119","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":8.61739,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-14 00:58:47","TRTEDTM":"2022-02-15 20:00:07","TRT01SDTM":"2020-01-14 00:58:47","TRT01EDTM":"2021-02-15 14:00:07","TRT02SDTM":"2021-02-15 14:00:07","TRT02EDTM":"2022-02-15 20:00:07","AP01SDTM":"2020-01-14 00:58:47","AP01EDTM":"2021-02-15 14:00:07","AP02SDTM":"2021-02-15 14:00:07","AP02EDTM":"2022-02-15 20:00:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":764,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-16","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8384,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87323,"AVALU":"g/L","BASE2":2.88044,"BASE":2.87323,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.00721,"PCHG2":-0.25024,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-25 00:58:47","ADY":102,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-119","SUBJID":"id-119","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":8.61739,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-14 00:58:47","TRTEDTM":"2022-02-15 20:00:07","TRT01SDTM":"2020-01-14 00:58:47","TRT01EDTM":"2021-02-15 14:00:07","TRT02SDTM":"2021-02-15 14:00:07","TRT02EDTM":"2022-02-15 20:00:07","AP01SDTM":"2020-01-14 00:58:47","AP01EDTM":"2021-02-15 14:00:07","AP02SDTM":"2021-02-15 14:00:07","AP02EDTM":"2022-02-15 20:00:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":764,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-16","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3391,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91692,"AVALU":"g/L","BASE2":2.88044,"BASE":2.87323,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03649,"PCHG2":1.26669,"CHG":0.04369,"PCHG":1.52074,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-21 00:58:47","ADY":251,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-119","SUBJID":"id-119","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":8.61739,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-14 00:58:47","TRTEDTM":"2022-02-15 20:00:07","TRT01SDTM":"2020-01-14 00:58:47","TRT01EDTM":"2021-02-15 14:00:07","TRT02SDTM":"2021-02-15 14:00:07","TRT02EDTM":"2022-02-15 20:00:07","AP01SDTM":"2020-01-14 00:58:47","AP01EDTM":"2021-02-15 14:00:07","AP02SDTM":"2021-02-15 14:00:07","AP02EDTM":"2022-02-15 20:00:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":764,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-16","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1816,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95606,"AVALU":"g/L","BASE2":2.88044,"BASE":2.87323,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07562,"PCHG2":2.62537,"CHG":0.08283,"PCHG":2.88283,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-13 00:58:47","ADY":424,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-119","SUBJID":"id-119","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":8.61739,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-14 00:58:47","TRTEDTM":"2022-02-15 20:00:07","TRT01SDTM":"2020-01-14 00:58:47","TRT01EDTM":"2021-02-15 14:00:07","TRT02SDTM":"2021-02-15 14:00:07","TRT02EDTM":"2022-02-15 20:00:07","AP01SDTM":"2020-01-14 00:58:47","AP01EDTM":"2021-02-15 14:00:07","AP02SDTM":"2021-02-15 14:00:07","AP02EDTM":"2022-02-15 20:00:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":764,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-16","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1089,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8988,"AVALU":"g/L","BASE2":2.88044,"BASE":2.87323,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01836,"PCHG2":0.63752,"CHG":0.02557,"PCHG":0.88999,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-20 00:58:47","ADY":553,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-119","SUBJID":"id-119","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":8.61739,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-14 00:58:47","TRTEDTM":"2022-02-15 20:00:07","TRT01SDTM":"2020-01-14 00:58:47","TRT01EDTM":"2021-02-15 14:00:07","TRT02SDTM":"2021-02-15 14:00:07","TRT02EDTM":"2022-02-15 20:00:07","AP01SDTM":"2020-01-14 00:58:47","AP01EDTM":"2021-02-15 14:00:07","AP02SDTM":"2021-02-15 14:00:07","AP02EDTM":"2022-02-15 20:00:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":764,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-16","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5471,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9061,"AVALU":"g/L","BASE2":2.88044,"BASE":2.87323,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02566,"PCHG2":0.89075,"CHG":0.03287,"PCHG":1.14385,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-17 00:58:47","ADY":673,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-119","SUBJID":"id-119","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":8.61739,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-14 00:58:47","TRTEDTM":"2022-02-15 20:00:07","TRT01SDTM":"2020-01-14 00:58:47","TRT01EDTM":"2021-02-15 14:00:07","TRT02SDTM":"2021-02-15 14:00:07","TRT02EDTM":"2022-02-15 20:00:07","AP01SDTM":"2020-01-14 00:58:47","AP01EDTM":"2021-02-15 14:00:07","AP02SDTM":"2021-02-15 14:00:07","AP02EDTM":"2022-02-15 20:00:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":764,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-16","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2226,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93506,"AVALU":"g/L","BASE2":2.88044,"BASE":2.87323,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05462,"PCHG2":1.89623,"CHG":0.06183,"PCHG":2.15185,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-02 00:58:47","ADY":719,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-12","SUBJID":"id-12","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.24721,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-20 05:45:02","TRTEDTM":"2023-12-20 23:45:02","TRT01SDTM":"2020-12-20 05:45:02","TRT01EDTM":"2022-12-20 17:45:02","TRT02SDTM":"2022-12-20 17:45:02","TRT02EDTM":"2023-12-20 23:45:02","AP01SDTM":"2020-12-20 05:45:02","AP01EDTM":"2022-12-20 17:45:02","AP02SDTM":"2022-12-20 17:45:02","AP02EDTM":"2023-12-20 23:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":561,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.36709,"AVALU":"U/L","BASE2":4.36709,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-04-10 05:45:02","ADY":111,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-12","SUBJID":"id-12","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.24721,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-20 05:45:02","TRTEDTM":"2023-12-20 23:45:02","TRT01SDTM":"2020-12-20 05:45:02","TRT01EDTM":"2022-12-20 17:45:02","TRT02SDTM":"2022-12-20 17:45:02","TRT02EDTM":"2023-12-20 23:45:02","AP01SDTM":"2020-12-20 05:45:02","AP01EDTM":"2022-12-20 17:45:02","AP02SDTM":"2022-12-20 17:45:02","AP02EDTM":"2023-12-20 23:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3479,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.87885,"AVALU":"U/L","BASE2":4.36709,"BASE":14.87885,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":10.51176,"PCHG2":240.70423,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-17 05:45:02","ADY":148,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-12","SUBJID":"id-12","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.24721,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-20 05:45:02","TRTEDTM":"2023-12-20 23:45:02","TRT01SDTM":"2020-12-20 05:45:02","TRT01EDTM":"2022-12-20 17:45:02","TRT02SDTM":"2022-12-20 17:45:02","TRT02EDTM":"2023-12-20 23:45:02","AP01SDTM":"2020-12-20 05:45:02","AP01EDTM":"2022-12-20 17:45:02","AP02SDTM":"2022-12-20 17:45:02","AP02EDTM":"2023-12-20 23:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5041,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.31807,"AVALU":"U/L","BASE2":4.36709,"BASE":14.87885,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.95099,"PCHG2":67.57332,"CHG":-7.56078,"PCHG":-50.8156,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-16 05:45:02","ADY":392,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-12","SUBJID":"id-12","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.24721,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-20 05:45:02","TRTEDTM":"2023-12-20 23:45:02","TRT01SDTM":"2020-12-20 05:45:02","TRT01EDTM":"2022-12-20 17:45:02","TRT02SDTM":"2022-12-20 17:45:02","TRT02EDTM":"2023-12-20 23:45:02","AP01SDTM":"2020-12-20 05:45:02","AP01EDTM":"2022-12-20 17:45:02","AP02SDTM":"2022-12-20 17:45:02","AP02EDTM":"2023-12-20 23:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6566,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.99693,"AVALU":"U/L","BASE2":4.36709,"BASE":14.87885,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.62984,"PCHG2":335.00227,"CHG":4.11808,"PCHG":27.67739,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-07 05:45:02","ADY":442,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-12","SUBJID":"id-12","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.24721,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-20 05:45:02","TRTEDTM":"2023-12-20 23:45:02","TRT01SDTM":"2020-12-20 05:45:02","TRT01EDTM":"2022-12-20 17:45:02","TRT02SDTM":"2022-12-20 17:45:02","TRT02EDTM":"2023-12-20 23:45:02","AP01SDTM":"2020-12-20 05:45:02","AP01EDTM":"2022-12-20 17:45:02","AP02SDTM":"2022-12-20 17:45:02","AP02EDTM":"2023-12-20 23:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":737,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.84582,"AVALU":"U/L","BASE2":4.36709,"BASE":14.87885,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.47873,"PCHG2":262.84638,"CHG":0.96697,"PCHG":6.49894,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-24 05:45:02","ADY":490,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-12","SUBJID":"id-12","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.24721,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-20 05:45:02","TRTEDTM":"2023-12-20 23:45:02","TRT01SDTM":"2020-12-20 05:45:02","TRT01EDTM":"2022-12-20 17:45:02","TRT02SDTM":"2022-12-20 17:45:02","TRT02EDTM":"2023-12-20 23:45:02","AP01SDTM":"2020-12-20 05:45:02","AP01EDTM":"2022-12-20 17:45:02","AP02SDTM":"2022-12-20 17:45:02","AP02EDTM":"2023-12-20 23:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3019,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.49869,"AVALU":"U/L","BASE2":4.36709,"BASE":14.87885,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.1316,"PCHG2":300.6947,"CHG":2.61984,"PCHG":17.60779,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-16 05:45:02","ADY":635,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-12","SUBJID":"id-12","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.24721,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-20 05:45:02","TRTEDTM":"2023-12-20 23:45:02","TRT01SDTM":"2020-12-20 05:45:02","TRT01EDTM":"2022-12-20 17:45:02","TRT02SDTM":"2022-12-20 17:45:02","TRT02EDTM":"2023-12-20 23:45:02","AP01SDTM":"2020-12-20 05:45:02","AP01EDTM":"2022-12-20 17:45:02","AP02SDTM":"2022-12-20 17:45:02","AP02EDTM":"2023-12-20 23:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5794,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.44498,"AVALU":"U/L","BASE2":4.36709,"BASE":14.87885,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":20.07789,"PCHG2":459.75469,"CHG":9.56613,"PCHG":64.29344,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-30 05:45:02","ADY":679,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-12","SUBJID":"id-12","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.24721,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-20 05:45:02","TRTEDTM":"2023-12-20 23:45:02","TRT01SDTM":"2020-12-20 05:45:02","TRT01EDTM":"2022-12-20 17:45:02","TRT02SDTM":"2022-12-20 17:45:02","TRT02EDTM":"2023-12-20 23:45:02","AP01SDTM":"2020-12-20 05:45:02","AP01EDTM":"2022-12-20 17:45:02","AP02SDTM":"2022-12-20 17:45:02","AP02EDTM":"2023-12-20 23:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":558,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.01563,"AVALU":"mg/L","BASE2":10.01563,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"2","ADTM":"2021-04-10 05:45:02","ADY":111,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-12","SUBJID":"id-12","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.24721,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-20 05:45:02","TRTEDTM":"2023-12-20 23:45:02","TRT01SDTM":"2020-12-20 05:45:02","TRT01EDTM":"2022-12-20 17:45:02","TRT02SDTM":"2022-12-20 17:45:02","TRT02EDTM":"2023-12-20 23:45:02","AP01SDTM":"2020-12-20 05:45:02","AP01EDTM":"2022-12-20 17:45:02","AP02SDTM":"2022-12-20 17:45:02","AP02EDTM":"2023-12-20 23:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5323,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.38554,"AVALU":"mg/L","BASE2":10.01563,"BASE":10.38554,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.36991,"PCHG2":3.69336,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2021-05-17 05:45:02","ADY":148,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-12","SUBJID":"id-12","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.24721,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-20 05:45:02","TRTEDTM":"2023-12-20 23:45:02","TRT01SDTM":"2020-12-20 05:45:02","TRT01EDTM":"2022-12-20 17:45:02","TRT02SDTM":"2022-12-20 17:45:02","TRT02EDTM":"2023-12-20 23:45:02","AP01SDTM":"2020-12-20 05:45:02","AP01EDTM":"2022-12-20 17:45:02","AP02SDTM":"2022-12-20 17:45:02","AP02EDTM":"2023-12-20 23:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4410,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.72474,"AVALU":"mg/L","BASE2":10.01563,"BASE":10.38554,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.29089,"PCHG2":-2.90431,"CHG":-0.6608,"PCHG":-6.36268,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-01-16 05:45:02","ADY":392,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-12","SUBJID":"id-12","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.24721,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-20 05:45:02","TRTEDTM":"2023-12-20 23:45:02","TRT01SDTM":"2020-12-20 05:45:02","TRT01EDTM":"2022-12-20 17:45:02","TRT02SDTM":"2022-12-20 17:45:02","TRT02EDTM":"2023-12-20 23:45:02","AP01SDTM":"2020-12-20 05:45:02","AP01EDTM":"2022-12-20 17:45:02","AP02SDTM":"2022-12-20 17:45:02","AP02EDTM":"2023-12-20 23:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6991,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.65459,"AVALU":"mg/L","BASE2":10.01563,"BASE":10.38554,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.36104,"PCHG2":-3.60477,"CHG":-0.73095,"PCHG":-7.03819,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-03-07 05:45:02","ADY":442,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-12","SUBJID":"id-12","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.24721,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-20 05:45:02","TRTEDTM":"2023-12-20 23:45:02","TRT01SDTM":"2020-12-20 05:45:02","TRT01EDTM":"2022-12-20 17:45:02","TRT02SDTM":"2022-12-20 17:45:02","TRT02EDTM":"2023-12-20 23:45:02","AP01SDTM":"2020-12-20 05:45:02","AP01EDTM":"2022-12-20 17:45:02","AP02SDTM":"2022-12-20 17:45:02","AP02EDTM":"2023-12-20 23:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4216,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.18852,"AVALU":"mg/L","BASE2":10.01563,"BASE":10.38554,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17289,"PCHG2":1.72617,"CHG":-0.19703,"PCHG":-1.89713,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"1","BTOXGR":"2","ADTM":"2022-04-24 05:45:02","ADY":490,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-12","SUBJID":"id-12","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.24721,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-20 05:45:02","TRTEDTM":"2023-12-20 23:45:02","TRT01SDTM":"2020-12-20 05:45:02","TRT01EDTM":"2022-12-20 17:45:02","TRT02SDTM":"2022-12-20 17:45:02","TRT02EDTM":"2023-12-20 23:45:02","AP01SDTM":"2020-12-20 05:45:02","AP01EDTM":"2022-12-20 17:45:02","AP02SDTM":"2022-12-20 17:45:02","AP02EDTM":"2023-12-20 23:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2103,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.0078,"AVALU":"mg/L","BASE2":10.01563,"BASE":10.38554,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.00783,"PCHG2":-10.06252,"CHG":-1.37774,"PCHG":-13.26593,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-09-16 05:45:02","ADY":635,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-12","SUBJID":"id-12","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.24721,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-20 05:45:02","TRTEDTM":"2023-12-20 23:45:02","TRT01SDTM":"2020-12-20 05:45:02","TRT01EDTM":"2022-12-20 17:45:02","TRT02SDTM":"2022-12-20 17:45:02","TRT02EDTM":"2023-12-20 23:45:02","AP01SDTM":"2020-12-20 05:45:02","AP01EDTM":"2022-12-20 17:45:02","AP02SDTM":"2022-12-20 17:45:02","AP02EDTM":"2023-12-20 23:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1026,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.72711,"AVALU":"mg/L","BASE2":10.01563,"BASE":10.38554,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.28852,"PCHG2":-12.86511,"CHG":-1.65844,"PCHG":-15.96869,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-10-30 05:45:02","ADY":679,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-12","SUBJID":"id-12","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.24721,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-20 05:45:02","TRTEDTM":"2023-12-20 23:45:02","TRT01SDTM":"2020-12-20 05:45:02","TRT01EDTM":"2022-12-20 17:45:02","TRT02SDTM":"2022-12-20 17:45:02","TRT02EDTM":"2023-12-20 23:45:02","AP01SDTM":"2020-12-20 05:45:02","AP01EDTM":"2022-12-20 17:45:02","AP02SDTM":"2022-12-20 17:45:02","AP02EDTM":"2023-12-20 23:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":24,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95238,"AVALU":"g/L","BASE2":2.95238,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-10 05:45:02","ADY":111,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-12","SUBJID":"id-12","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.24721,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-20 05:45:02","TRTEDTM":"2023-12-20 23:45:02","TRT01SDTM":"2020-12-20 05:45:02","TRT01EDTM":"2022-12-20 17:45:02","TRT02SDTM":"2022-12-20 17:45:02","TRT02EDTM":"2023-12-20 23:45:02","AP01SDTM":"2020-12-20 05:45:02","AP01EDTM":"2022-12-20 17:45:02","AP02SDTM":"2022-12-20 17:45:02","AP02EDTM":"2023-12-20 23:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5149,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84826,"AVALU":"g/L","BASE2":2.95238,"BASE":2.84826,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.10412,"PCHG2":-3.52661,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-17 05:45:02","ADY":148,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-12","SUBJID":"id-12","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.24721,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-20 05:45:02","TRTEDTM":"2023-12-20 23:45:02","TRT01SDTM":"2020-12-20 05:45:02","TRT01EDTM":"2022-12-20 17:45:02","TRT02SDTM":"2022-12-20 17:45:02","TRT02EDTM":"2023-12-20 23:45:02","AP01SDTM":"2020-12-20 05:45:02","AP01EDTM":"2022-12-20 17:45:02","AP02SDTM":"2022-12-20 17:45:02","AP02EDTM":"2023-12-20 23:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3243,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90073,"AVALU":"g/L","BASE2":2.95238,"BASE":2.84826,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05166,"PCHG2":-1.74961,"CHG":0.05246,"PCHG":1.84197,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-16 05:45:02","ADY":392,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-12","SUBJID":"id-12","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.24721,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-20 05:45:02","TRTEDTM":"2023-12-20 23:45:02","TRT01SDTM":"2020-12-20 05:45:02","TRT01EDTM":"2022-12-20 17:45:02","TRT02SDTM":"2022-12-20 17:45:02","TRT02EDTM":"2023-12-20 23:45:02","AP01SDTM":"2020-12-20 05:45:02","AP01EDTM":"2022-12-20 17:45:02","AP02SDTM":"2022-12-20 17:45:02","AP02EDTM":"2023-12-20 23:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2457,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83963,"AVALU":"g/L","BASE2":2.95238,"BASE":2.84826,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11275,"PCHG2":-3.81888,"CHG":-0.00863,"PCHG":-0.30295,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-07 05:45:02","ADY":442,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-12","SUBJID":"id-12","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.24721,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-20 05:45:02","TRTEDTM":"2023-12-20 23:45:02","TRT01SDTM":"2020-12-20 05:45:02","TRT01EDTM":"2022-12-20 17:45:02","TRT02SDTM":"2022-12-20 17:45:02","TRT02EDTM":"2023-12-20 23:45:02","AP01SDTM":"2020-12-20 05:45:02","AP01EDTM":"2022-12-20 17:45:02","AP02SDTM":"2022-12-20 17:45:02","AP02EDTM":"2023-12-20 23:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1415,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9253,"AVALU":"g/L","BASE2":2.95238,"BASE":2.84826,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02708,"PCHG2":-0.91735,"CHG":0.07704,"PCHG":2.70464,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-24 05:45:02","ADY":490,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-12","SUBJID":"id-12","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.24721,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-20 05:45:02","TRTEDTM":"2023-12-20 23:45:02","TRT01SDTM":"2020-12-20 05:45:02","TRT01EDTM":"2022-12-20 17:45:02","TRT02SDTM":"2022-12-20 17:45:02","TRT02EDTM":"2023-12-20 23:45:02","AP01SDTM":"2020-12-20 05:45:02","AP01EDTM":"2022-12-20 17:45:02","AP02SDTM":"2022-12-20 17:45:02","AP02EDTM":"2023-12-20 23:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":225,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9592,"AVALU":"g/L","BASE2":2.95238,"BASE":2.84826,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00681,"PCHG2":0.23074,"CHG":0.11093,"PCHG":3.89471,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-16 05:45:02","ADY":635,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-12","SUBJID":"id-12","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.24721,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-20 05:45:02","TRTEDTM":"2023-12-20 23:45:02","TRT01SDTM":"2020-12-20 05:45:02","TRT01EDTM":"2022-12-20 17:45:02","TRT02SDTM":"2022-12-20 17:45:02","TRT02EDTM":"2023-12-20 23:45:02","AP01SDTM":"2020-12-20 05:45:02","AP01EDTM":"2022-12-20 17:45:02","AP02SDTM":"2022-12-20 17:45:02","AP02EDTM":"2023-12-20 23:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2719,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83383,"AVALU":"g/L","BASE2":2.95238,"BASE":2.84826,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11855,"PCHG2":-4.0155,"CHG":-0.01443,"PCHG":-0.50676,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-30 05:45:02","ADY":679,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-123","SUBJID":"id-123","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.88609,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-24","TRTSDTM":"2020-01-28 17:26:17","TRTEDTM":"2022-02-16 13:12:24","TRT01SDTM":"2020-01-28 17:26:17","TRT01EDTM":"2021-02-16 07:12:24","TRT02SDTM":"2021-02-16 07:12:24","TRT02EDTM":"2022-02-16 13:12:24","AP01SDTM":"2020-01-28 17:26:17","AP01EDTM":"2021-02-16 07:12:24","AP02SDTM":"2021-02-16 07:12:24","AP02EDTM":"2022-02-16 13:12:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":750,"DCSREAS":"DEATH","DTHDT":"2022-02-17","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-17","DTHADY":750,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6181,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.68252,"AVALU":"U/L","BASE2":10.68252,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-14 17:26:17","ADY":168,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-123","SUBJID":"id-123","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.88609,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-24","TRTSDTM":"2020-01-28 17:26:17","TRTEDTM":"2022-02-16 13:12:24","TRT01SDTM":"2020-01-28 17:26:17","TRT01EDTM":"2021-02-16 07:12:24","TRT02SDTM":"2021-02-16 07:12:24","TRT02EDTM":"2022-02-16 13:12:24","AP01SDTM":"2020-01-28 17:26:17","AP01EDTM":"2021-02-16 07:12:24","AP02SDTM":"2021-02-16 07:12:24","AP02EDTM":"2022-02-16 13:12:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":750,"DCSREAS":"DEATH","DTHDT":"2022-02-17","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-17","DTHADY":750,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3998,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.93299,"AVALU":"U/L","BASE2":10.68252,"BASE":18.93299,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":8.25048,"PCHG2":77.23344,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-01 17:26:17","ADY":217,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-123","SUBJID":"id-123","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.88609,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-24","TRTSDTM":"2020-01-28 17:26:17","TRTEDTM":"2022-02-16 13:12:24","TRT01SDTM":"2020-01-28 17:26:17","TRT01EDTM":"2021-02-16 07:12:24","TRT02SDTM":"2021-02-16 07:12:24","TRT02EDTM":"2022-02-16 13:12:24","AP01SDTM":"2020-01-28 17:26:17","AP01EDTM":"2021-02-16 07:12:24","AP02SDTM":"2021-02-16 07:12:24","AP02EDTM":"2022-02-16 13:12:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":750,"DCSREAS":"DEATH","DTHDT":"2022-02-17","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-17","DTHADY":750,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1330,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.57308,"AVALU":"U/L","BASE2":10.68252,"BASE":18.93299,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":23.89056,"PCHG2":223.64163,"CHG":15.64008,"PCHG":82.60755,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-10 17:26:17","ADY":226,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-123","SUBJID":"id-123","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.88609,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-24","TRTSDTM":"2020-01-28 17:26:17","TRTEDTM":"2022-02-16 13:12:24","TRT01SDTM":"2020-01-28 17:26:17","TRT01EDTM":"2021-02-16 07:12:24","TRT02SDTM":"2021-02-16 07:12:24","TRT02EDTM":"2022-02-16 13:12:24","AP01SDTM":"2020-01-28 17:26:17","AP01EDTM":"2021-02-16 07:12:24","AP02SDTM":"2021-02-16 07:12:24","AP02EDTM":"2022-02-16 13:12:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":750,"DCSREAS":"DEATH","DTHDT":"2022-02-17","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-17","DTHADY":750,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":240,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.52391,"AVALU":"U/L","BASE2":10.68252,"BASE":18.93299,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.84139,"PCHG2":129.57051,"CHG":5.59092,"PCHG":29.53002,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-29 17:26:17","ADY":336,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-123","SUBJID":"id-123","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.88609,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-24","TRTSDTM":"2020-01-28 17:26:17","TRTEDTM":"2022-02-16 13:12:24","TRT01SDTM":"2020-01-28 17:26:17","TRT01EDTM":"2021-02-16 07:12:24","TRT02SDTM":"2021-02-16 07:12:24","TRT02EDTM":"2022-02-16 13:12:24","AP01SDTM":"2020-01-28 17:26:17","AP01EDTM":"2021-02-16 07:12:24","AP02SDTM":"2021-02-16 07:12:24","AP02EDTM":"2022-02-16 13:12:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":750,"DCSREAS":"DEATH","DTHDT":"2022-02-17","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-17","DTHADY":750,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5980,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.53317,"AVALU":"U/L","BASE2":10.68252,"BASE":18.93299,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.85066,"PCHG2":176.46266,"CHG":10.60018,"PCHG":55.98786,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-21 17:26:17","ADY":359,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-123","SUBJID":"id-123","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.88609,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-24","TRTSDTM":"2020-01-28 17:26:17","TRTEDTM":"2022-02-16 13:12:24","TRT01SDTM":"2020-01-28 17:26:17","TRT01EDTM":"2021-02-16 07:12:24","TRT02SDTM":"2021-02-16 07:12:24","TRT02EDTM":"2022-02-16 13:12:24","AP01SDTM":"2020-01-28 17:26:17","AP01EDTM":"2021-02-16 07:12:24","AP02SDTM":"2021-02-16 07:12:24","AP02EDTM":"2022-02-16 13:12:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":750,"DCSREAS":"DEATH","DTHDT":"2022-02-17","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-17","DTHADY":750,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4385,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.27684,"AVALU":"U/L","BASE2":10.68252,"BASE":18.93299,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.59432,"PCHG2":5.56352,"CHG":-7.65615,"PCHG":-40.43815,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-23 17:26:17","ADY":392,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-123","SUBJID":"id-123","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.88609,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-24","TRTSDTM":"2020-01-28 17:26:17","TRTEDTM":"2022-02-16 13:12:24","TRT01SDTM":"2020-01-28 17:26:17","TRT01EDTM":"2021-02-16 07:12:24","TRT02SDTM":"2021-02-16 07:12:24","TRT02EDTM":"2022-02-16 13:12:24","AP01SDTM":"2020-01-28 17:26:17","AP01EDTM":"2021-02-16 07:12:24","AP02SDTM":"2021-02-16 07:12:24","AP02EDTM":"2022-02-16 13:12:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":750,"DCSREAS":"DEATH","DTHDT":"2022-02-17","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-17","DTHADY":750,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":768,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.90519,"AVALU":"U/L","BASE2":10.68252,"BASE":18.93299,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.22267,"PCHG2":58.25097,"CHG":-2.02781,"PCHG":-10.71043,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-23 17:26:17","ADY":451,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-123","SUBJID":"id-123","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.88609,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-24","TRTSDTM":"2020-01-28 17:26:17","TRTEDTM":"2022-02-16 13:12:24","TRT01SDTM":"2020-01-28 17:26:17","TRT01EDTM":"2021-02-16 07:12:24","TRT02SDTM":"2021-02-16 07:12:24","TRT02EDTM":"2022-02-16 13:12:24","AP01SDTM":"2020-01-28 17:26:17","AP01EDTM":"2021-02-16 07:12:24","AP02SDTM":"2021-02-16 07:12:24","AP02EDTM":"2022-02-16 13:12:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":750,"DCSREAS":"DEATH","DTHDT":"2022-02-17","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-17","DTHADY":750,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3007,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.27422,"AVALU":"mg/L","BASE2":9.27422,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-14 17:26:17","ADY":168,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-123","SUBJID":"id-123","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.88609,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-24","TRTSDTM":"2020-01-28 17:26:17","TRTEDTM":"2022-02-16 13:12:24","TRT01SDTM":"2020-01-28 17:26:17","TRT01EDTM":"2021-02-16 07:12:24","TRT02SDTM":"2021-02-16 07:12:24","TRT02EDTM":"2022-02-16 13:12:24","AP01SDTM":"2020-01-28 17:26:17","AP01EDTM":"2021-02-16 07:12:24","AP02SDTM":"2021-02-16 07:12:24","AP02EDTM":"2022-02-16 13:12:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":750,"DCSREAS":"DEATH","DTHDT":"2022-02-17","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-17","DTHADY":750,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5766,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.61628,"AVALU":"mg/L","BASE2":9.27422,"BASE":9.61628,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.34206,"PCHG2":3.68831,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-01 17:26:17","ADY":217,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-123","SUBJID":"id-123","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.88609,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-24","TRTSDTM":"2020-01-28 17:26:17","TRTEDTM":"2022-02-16 13:12:24","TRT01SDTM":"2020-01-28 17:26:17","TRT01EDTM":"2021-02-16 07:12:24","TRT02SDTM":"2021-02-16 07:12:24","TRT02EDTM":"2022-02-16 13:12:24","AP01SDTM":"2020-01-28 17:26:17","AP01EDTM":"2021-02-16 07:12:24","AP02SDTM":"2021-02-16 07:12:24","AP02EDTM":"2022-02-16 13:12:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":750,"DCSREAS":"DEATH","DTHDT":"2022-02-17","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-17","DTHADY":750,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6019,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.04543,"AVALU":"mg/L","BASE2":9.27422,"BASE":9.61628,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.2288,"PCHG2":-2.46703,"CHG":-0.57086,"PCHG":-5.93638,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-10 17:26:17","ADY":226,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-123","SUBJID":"id-123","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.88609,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-24","TRTSDTM":"2020-01-28 17:26:17","TRTEDTM":"2022-02-16 13:12:24","TRT01SDTM":"2020-01-28 17:26:17","TRT01EDTM":"2021-02-16 07:12:24","TRT02SDTM":"2021-02-16 07:12:24","TRT02EDTM":"2022-02-16 13:12:24","AP01SDTM":"2020-01-28 17:26:17","AP01EDTM":"2021-02-16 07:12:24","AP02SDTM":"2021-02-16 07:12:24","AP02EDTM":"2022-02-16 13:12:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":750,"DCSREAS":"DEATH","DTHDT":"2022-02-17","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-17","DTHADY":750,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":13,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.10199,"AVALU":"mg/L","BASE2":9.27422,"BASE":9.61628,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.82776,"PCHG2":8.92543,"CHG":0.4857,"PCHG":5.05083,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-12-29 17:26:17","ADY":336,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-123","SUBJID":"id-123","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.88609,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-24","TRTSDTM":"2020-01-28 17:26:17","TRTEDTM":"2022-02-16 13:12:24","TRT01SDTM":"2020-01-28 17:26:17","TRT01EDTM":"2021-02-16 07:12:24","TRT02SDTM":"2021-02-16 07:12:24","TRT02EDTM":"2022-02-16 13:12:24","AP01SDTM":"2020-01-28 17:26:17","AP01EDTM":"2021-02-16 07:12:24","AP02SDTM":"2021-02-16 07:12:24","AP02EDTM":"2022-02-16 13:12:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":750,"DCSREAS":"DEATH","DTHDT":"2022-02-17","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-17","DTHADY":750,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3487,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.98767,"AVALU":"mg/L","BASE2":9.27422,"BASE":9.61628,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.28655,"PCHG2":-13.87231,"CHG":-1.62861,"PCHG":-16.93596,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-01-21 17:26:17","ADY":359,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-123","SUBJID":"id-123","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.88609,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-24","TRTSDTM":"2020-01-28 17:26:17","TRTEDTM":"2022-02-16 13:12:24","TRT01SDTM":"2020-01-28 17:26:17","TRT01EDTM":"2021-02-16 07:12:24","TRT02SDTM":"2021-02-16 07:12:24","TRT02EDTM":"2022-02-16 13:12:24","AP01SDTM":"2020-01-28 17:26:17","AP01EDTM":"2021-02-16 07:12:24","AP02SDTM":"2021-02-16 07:12:24","AP02EDTM":"2022-02-16 13:12:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":750,"DCSREAS":"DEATH","DTHDT":"2022-02-17","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-17","DTHADY":750,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2712,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.24576,"AVALU":"mg/L","BASE2":9.27422,"BASE":9.61628,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.97154,"PCHG2":10.47572,"CHG":0.62948,"PCHG":6.54598,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-02-23 17:26:17","ADY":392,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-123","SUBJID":"id-123","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.88609,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-24","TRTSDTM":"2020-01-28 17:26:17","TRTEDTM":"2022-02-16 13:12:24","TRT01SDTM":"2020-01-28 17:26:17","TRT01EDTM":"2021-02-16 07:12:24","TRT02SDTM":"2021-02-16 07:12:24","TRT02EDTM":"2022-02-16 13:12:24","AP01SDTM":"2020-01-28 17:26:17","AP01EDTM":"2021-02-16 07:12:24","AP02SDTM":"2021-02-16 07:12:24","AP02EDTM":"2022-02-16 13:12:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":750,"DCSREAS":"DEATH","DTHDT":"2022-02-17","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-17","DTHADY":750,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1480,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.05957,"AVALU":"mg/L","BASE2":9.27422,"BASE":9.61628,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.21466,"PCHG2":-13.09712,"CHG":-1.55672,"PCHG":-16.18836,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-23 17:26:17","ADY":451,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-123","SUBJID":"id-123","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.88609,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-24","TRTSDTM":"2020-01-28 17:26:17","TRTEDTM":"2022-02-16 13:12:24","TRT01SDTM":"2020-01-28 17:26:17","TRT01EDTM":"2021-02-16 07:12:24","TRT02SDTM":"2021-02-16 07:12:24","TRT02EDTM":"2022-02-16 13:12:24","AP01SDTM":"2020-01-28 17:26:17","AP01EDTM":"2021-02-16 07:12:24","AP02SDTM":"2021-02-16 07:12:24","AP02EDTM":"2022-02-16 13:12:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":750,"DCSREAS":"DEATH","DTHDT":"2022-02-17","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-17","DTHADY":750,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4721,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96554,"AVALU":"g/L","BASE2":2.96554,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-14 17:26:17","ADY":168,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-123","SUBJID":"id-123","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.88609,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-24","TRTSDTM":"2020-01-28 17:26:17","TRTEDTM":"2022-02-16 13:12:24","TRT01SDTM":"2020-01-28 17:26:17","TRT01EDTM":"2021-02-16 07:12:24","TRT02SDTM":"2021-02-16 07:12:24","TRT02EDTM":"2022-02-16 13:12:24","AP01SDTM":"2020-01-28 17:26:17","AP01EDTM":"2021-02-16 07:12:24","AP02SDTM":"2021-02-16 07:12:24","AP02EDTM":"2022-02-16 13:12:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":750,"DCSREAS":"DEATH","DTHDT":"2022-02-17","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-17","DTHADY":750,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1498,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8206,"AVALU":"g/L","BASE2":2.96554,"BASE":2.8206,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.14495,"PCHG2":-4.88768,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-01 17:26:17","ADY":217,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-123","SUBJID":"id-123","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.88609,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-24","TRTSDTM":"2020-01-28 17:26:17","TRTEDTM":"2022-02-16 13:12:24","TRT01SDTM":"2020-01-28 17:26:17","TRT01EDTM":"2021-02-16 07:12:24","TRT02SDTM":"2021-02-16 07:12:24","TRT02EDTM":"2022-02-16 13:12:24","AP01SDTM":"2020-01-28 17:26:17","AP01EDTM":"2021-02-16 07:12:24","AP02SDTM":"2021-02-16 07:12:24","AP02EDTM":"2022-02-16 13:12:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":750,"DCSREAS":"DEATH","DTHDT":"2022-02-17","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-17","DTHADY":750,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":245,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90169,"AVALU":"g/L","BASE2":2.96554,"BASE":2.8206,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06385,"PCHG2":-2.15305,"CHG":0.0811,"PCHG":2.87516,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-10 17:26:17","ADY":226,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-123","SUBJID":"id-123","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.88609,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-24","TRTSDTM":"2020-01-28 17:26:17","TRTEDTM":"2022-02-16 13:12:24","TRT01SDTM":"2020-01-28 17:26:17","TRT01EDTM":"2021-02-16 07:12:24","TRT02SDTM":"2021-02-16 07:12:24","TRT02EDTM":"2022-02-16 13:12:24","AP01SDTM":"2020-01-28 17:26:17","AP01EDTM":"2021-02-16 07:12:24","AP02SDTM":"2021-02-16 07:12:24","AP02EDTM":"2022-02-16 13:12:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":750,"DCSREAS":"DEATH","DTHDT":"2022-02-17","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-17","DTHADY":750,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3941,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0343,"AVALU":"g/L","BASE2":2.96554,"BASE":2.8206,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06875,"PCHG2":2.31844,"CHG":0.2137,"PCHG":7.57644,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-12-29 17:26:17","ADY":336,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-123","SUBJID":"id-123","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.88609,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-24","TRTSDTM":"2020-01-28 17:26:17","TRTEDTM":"2022-02-16 13:12:24","TRT01SDTM":"2020-01-28 17:26:17","TRT01EDTM":"2021-02-16 07:12:24","TRT02SDTM":"2021-02-16 07:12:24","TRT02EDTM":"2022-02-16 13:12:24","AP01SDTM":"2020-01-28 17:26:17","AP01EDTM":"2021-02-16 07:12:24","AP02SDTM":"2021-02-16 07:12:24","AP02EDTM":"2022-02-16 13:12:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":750,"DCSREAS":"DEATH","DTHDT":"2022-02-17","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-17","DTHADY":750,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":917,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99539,"AVALU":"g/L","BASE2":2.96554,"BASE":2.8206,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02985,"PCHG2":1.0064,"CHG":0.17479,"PCHG":6.19697,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-21 17:26:17","ADY":359,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-123","SUBJID":"id-123","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.88609,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-24","TRTSDTM":"2020-01-28 17:26:17","TRTEDTM":"2022-02-16 13:12:24","TRT01SDTM":"2020-01-28 17:26:17","TRT01EDTM":"2021-02-16 07:12:24","TRT02SDTM":"2021-02-16 07:12:24","TRT02EDTM":"2022-02-16 13:12:24","AP01SDTM":"2020-01-28 17:26:17","AP01EDTM":"2021-02-16 07:12:24","AP02SDTM":"2021-02-16 07:12:24","AP02EDTM":"2022-02-16 13:12:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":750,"DCSREAS":"DEATH","DTHDT":"2022-02-17","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-17","DTHADY":750,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4103,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94034,"AVALU":"g/L","BASE2":2.96554,"BASE":2.8206,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0252,"PCHG2":-0.84984,"CHG":0.11974,"PCHG":4.24534,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-23 17:26:17","ADY":392,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-123","SUBJID":"id-123","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.88609,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-24","TRTSDTM":"2020-01-28 17:26:17","TRTEDTM":"2022-02-16 13:12:24","TRT01SDTM":"2020-01-28 17:26:17","TRT01EDTM":"2021-02-16 07:12:24","TRT02SDTM":"2021-02-16 07:12:24","TRT02EDTM":"2022-02-16 13:12:24","AP01SDTM":"2020-01-28 17:26:17","AP01EDTM":"2021-02-16 07:12:24","AP02SDTM":"2021-02-16 07:12:24","AP02EDTM":"2022-02-16 13:12:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":750,"DCSREAS":"DEATH","DTHDT":"2022-02-17","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-17","DTHADY":750,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":9,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01284,"AVALU":"g/L","BASE2":2.96554,"BASE":2.8206,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0473,"PCHG2":1.59498,"CHG":0.19225,"PCHG":6.8158,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2021-04-23 17:26:17","ADY":451,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-133","SUBJID":"id-133","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.31712,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-08 03:10:13","TRTEDTM":"2022-02-17 17:39:37","TRT01SDTM":"2020-08-08 03:10:13","TRT01EDTM":"2021-02-17 11:39:37","TRT02SDTM":"2021-02-17 11:39:37","TRT02EDTM":"2022-02-17 17:39:37","AP01SDTM":"2020-08-08 03:10:13","AP01EDTM":"2021-02-17 11:39:37","AP02SDTM":"2021-02-17 11:39:37","AP02EDTM":"2022-02-17 17:39:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":559,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7780,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":35.78429,"AVALU":"U/L","BASE2":35.78429,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-14 03:10:13","ADY":6,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-133","SUBJID":"id-133","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.31712,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-08 03:10:13","TRTEDTM":"2022-02-17 17:39:37","TRT01SDTM":"2020-08-08 03:10:13","TRT01EDTM":"2021-02-17 11:39:37","TRT02SDTM":"2021-02-17 11:39:37","TRT02EDTM":"2022-02-17 17:39:37","AP01SDTM":"2020-08-08 03:10:13","AP01EDTM":"2021-02-17 11:39:37","AP02SDTM":"2021-02-17 11:39:37","AP02EDTM":"2022-02-17 17:39:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":559,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4362,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.4048,"AVALU":"U/L","BASE2":35.78429,"BASE":31.4048,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-4.37949,"PCHG2":-12.23859,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-23 03:10:13","ADY":15,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-133","SUBJID":"id-133","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.31712,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-08 03:10:13","TRTEDTM":"2022-02-17 17:39:37","TRT01SDTM":"2020-08-08 03:10:13","TRT01EDTM":"2021-02-17 11:39:37","TRT02SDTM":"2021-02-17 11:39:37","TRT02EDTM":"2022-02-17 17:39:37","AP01SDTM":"2020-08-08 03:10:13","AP01EDTM":"2021-02-17 11:39:37","AP02SDTM":"2021-02-17 11:39:37","AP02EDTM":"2022-02-17 17:39:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":559,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3912,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.83184,"AVALU":"U/L","BASE2":35.78429,"BASE":31.4048,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.95245,"PCHG2":-38.99043,"CHG":-9.57296,"PCHG":-30.48247,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-03 03:10:13","ADY":56,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-133","SUBJID":"id-133","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.31712,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-08 03:10:13","TRTEDTM":"2022-02-17 17:39:37","TRT01SDTM":"2020-08-08 03:10:13","TRT01EDTM":"2021-02-17 11:39:37","TRT02SDTM":"2021-02-17 11:39:37","TRT02EDTM":"2022-02-17 17:39:37","AP01SDTM":"2020-08-08 03:10:13","AP01EDTM":"2021-02-17 11:39:37","AP02SDTM":"2021-02-17 11:39:37","AP02EDTM":"2022-02-17 17:39:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":559,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7601,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.61561,"AVALU":"U/L","BASE2":35.78429,"BASE":31.4048,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-30.16869,"PCHG2":-84.30706,"CHG":-25.78919,"PCHG":-82.11864,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-12-13 03:10:13","ADY":127,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-133","SUBJID":"id-133","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.31712,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-08 03:10:13","TRTEDTM":"2022-02-17 17:39:37","TRT01SDTM":"2020-08-08 03:10:13","TRT01EDTM":"2021-02-17 11:39:37","TRT02SDTM":"2021-02-17 11:39:37","TRT02EDTM":"2022-02-17 17:39:37","AP01SDTM":"2020-08-08 03:10:13","AP01EDTM":"2021-02-17 11:39:37","AP02SDTM":"2021-02-17 11:39:37","AP02EDTM":"2022-02-17 17:39:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":559,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1609,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.24319,"AVALU":"U/L","BASE2":35.78429,"BASE":31.4048,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-34.5411,"PCHG2":-96.52587,"CHG":-30.16161,"PCHG":-96.0414,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-02-21 03:10:13","ADY":197,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-133","SUBJID":"id-133","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.31712,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-08 03:10:13","TRTEDTM":"2022-02-17 17:39:37","TRT01SDTM":"2020-08-08 03:10:13","TRT01EDTM":"2021-02-17 11:39:37","TRT02SDTM":"2021-02-17 11:39:37","TRT02EDTM":"2022-02-17 17:39:37","AP01SDTM":"2020-08-08 03:10:13","AP01EDTM":"2021-02-17 11:39:37","AP02SDTM":"2021-02-17 11:39:37","AP02EDTM":"2022-02-17 17:39:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":559,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4119,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.52095,"AVALU":"U/L","BASE2":35.78429,"BASE":31.4048,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.26334,"PCHG2":-25.88662,"CHG":-4.88385,"PCHG":-15.55129,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-13 03:10:13","ADY":370,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-133","SUBJID":"id-133","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.31712,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-08 03:10:13","TRTEDTM":"2022-02-17 17:39:37","TRT01SDTM":"2020-08-08 03:10:13","TRT01EDTM":"2021-02-17 11:39:37","TRT02SDTM":"2021-02-17 11:39:37","TRT02EDTM":"2022-02-17 17:39:37","AP01SDTM":"2020-08-08 03:10:13","AP01EDTM":"2021-02-17 11:39:37","AP02SDTM":"2021-02-17 11:39:37","AP02EDTM":"2022-02-17 17:39:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":559,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6522,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.60659,"AVALU":"U/L","BASE2":35.78429,"BASE":31.4048,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-24.1777,"PCHG2":-67.56512,"CHG":-19.79821,"PCHG":-63.04198,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-23 03:10:13","ADY":502,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-133","SUBJID":"id-133","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.31712,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-08 03:10:13","TRTEDTM":"2022-02-17 17:39:37","TRT01SDTM":"2020-08-08 03:10:13","TRT01EDTM":"2021-02-17 11:39:37","TRT02SDTM":"2021-02-17 11:39:37","TRT02EDTM":"2022-02-17 17:39:37","AP01SDTM":"2020-08-08 03:10:13","AP01EDTM":"2021-02-17 11:39:37","AP02SDTM":"2021-02-17 11:39:37","AP02EDTM":"2022-02-17 17:39:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":559,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7813,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.12721,"AVALU":"mg/L","BASE2":8.12721,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-14 03:10:13","ADY":6,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-133","SUBJID":"id-133","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.31712,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-08 03:10:13","TRTEDTM":"2022-02-17 17:39:37","TRT01SDTM":"2020-08-08 03:10:13","TRT01EDTM":"2021-02-17 11:39:37","TRT02SDTM":"2021-02-17 11:39:37","TRT02EDTM":"2022-02-17 17:39:37","AP01SDTM":"2020-08-08 03:10:13","AP01EDTM":"2021-02-17 11:39:37","AP02SDTM":"2021-02-17 11:39:37","AP02EDTM":"2022-02-17 17:39:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":559,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1331,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.5397,"AVALU":"mg/L","BASE2":8.12721,"BASE":9.5397,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.41249,"PCHG2":17.37971,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-23 03:10:13","ADY":15,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-133","SUBJID":"id-133","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.31712,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-08 03:10:13","TRTEDTM":"2022-02-17 17:39:37","TRT01SDTM":"2020-08-08 03:10:13","TRT01EDTM":"2021-02-17 11:39:37","TRT02SDTM":"2021-02-17 11:39:37","TRT02EDTM":"2022-02-17 17:39:37","AP01SDTM":"2020-08-08 03:10:13","AP01EDTM":"2021-02-17 11:39:37","AP02SDTM":"2021-02-17 11:39:37","AP02EDTM":"2022-02-17 17:39:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":559,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3699,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.01129,"AVALU":"mg/L","BASE2":8.12721,"BASE":9.5397,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11593,"PCHG2":-1.42638,"CHG":-1.52841,"PCHG":-16.02159,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-03 03:10:13","ADY":56,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-133","SUBJID":"id-133","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.31712,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-08 03:10:13","TRTEDTM":"2022-02-17 17:39:37","TRT01SDTM":"2020-08-08 03:10:13","TRT01EDTM":"2021-02-17 11:39:37","TRT02SDTM":"2021-02-17 11:39:37","TRT02EDTM":"2022-02-17 17:39:37","AP01SDTM":"2020-08-08 03:10:13","AP01EDTM":"2021-02-17 11:39:37","AP02SDTM":"2021-02-17 11:39:37","AP02EDTM":"2022-02-17 17:39:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":559,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2425,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.15304,"AVALU":"mg/L","BASE2":8.12721,"BASE":9.5397,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.97417,"PCHG2":-11.98653,"CHG":-2.38666,"PCHG":-25.01816,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-12-13 03:10:13","ADY":127,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-133","SUBJID":"id-133","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.31712,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-08 03:10:13","TRTEDTM":"2022-02-17 17:39:37","TRT01SDTM":"2020-08-08 03:10:13","TRT01EDTM":"2021-02-17 11:39:37","TRT02SDTM":"2021-02-17 11:39:37","TRT02EDTM":"2022-02-17 17:39:37","AP01SDTM":"2020-08-08 03:10:13","AP01EDTM":"2021-02-17 11:39:37","AP02SDTM":"2021-02-17 11:39:37","AP02EDTM":"2022-02-17 17:39:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":559,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7499,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.32186,"AVALU":"mg/L","BASE2":8.12721,"BASE":9.5397,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.19465,"PCHG2":27.00374,"CHG":0.78217,"PCHG":8.19906,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-02-21 03:10:13","ADY":197,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-133","SUBJID":"id-133","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.31712,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-08 03:10:13","TRTEDTM":"2022-02-17 17:39:37","TRT01SDTM":"2020-08-08 03:10:13","TRT01EDTM":"2021-02-17 11:39:37","TRT02SDTM":"2021-02-17 11:39:37","TRT02EDTM":"2022-02-17 17:39:37","AP01SDTM":"2020-08-08 03:10:13","AP01EDTM":"2021-02-17 11:39:37","AP02SDTM":"2021-02-17 11:39:37","AP02EDTM":"2022-02-17 17:39:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":559,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5711,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.70768,"AVALU":"mg/L","BASE2":8.12721,"BASE":9.5397,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.58046,"PCHG2":7.14221,"CHG":-0.83202,"PCHG":-8.7217,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-13 03:10:13","ADY":370,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-133","SUBJID":"id-133","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.31712,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-08 03:10:13","TRTEDTM":"2022-02-17 17:39:37","TRT01SDTM":"2020-08-08 03:10:13","TRT01EDTM":"2021-02-17 11:39:37","TRT02SDTM":"2021-02-17 11:39:37","TRT02EDTM":"2022-02-17 17:39:37","AP01SDTM":"2020-08-08 03:10:13","AP01EDTM":"2021-02-17 11:39:37","AP02SDTM":"2021-02-17 11:39:37","AP02EDTM":"2022-02-17 17:39:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":559,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1268,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.54881,"AVALU":"mg/L","BASE2":8.12721,"BASE":9.5397,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.4216,"PCHG2":17.49182,"CHG":0.00911,"PCHG":0.09551,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-23 03:10:13","ADY":502,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-133","SUBJID":"id-133","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.31712,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-08 03:10:13","TRTEDTM":"2022-02-17 17:39:37","TRT01SDTM":"2020-08-08 03:10:13","TRT01EDTM":"2021-02-17 11:39:37","TRT02SDTM":"2021-02-17 11:39:37","TRT02EDTM":"2022-02-17 17:39:37","AP01SDTM":"2020-08-08 03:10:13","AP01EDTM":"2021-02-17 11:39:37","AP02SDTM":"2021-02-17 11:39:37","AP02EDTM":"2022-02-17 17:39:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":559,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1507,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75457,"AVALU":"g/L","BASE2":2.75457,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"2","ADTM":"2020-08-14 03:10:13","ADY":6,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-133","SUBJID":"id-133","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.31712,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-08 03:10:13","TRTEDTM":"2022-02-17 17:39:37","TRT01SDTM":"2020-08-08 03:10:13","TRT01EDTM":"2021-02-17 11:39:37","TRT02SDTM":"2021-02-17 11:39:37","TRT02EDTM":"2022-02-17 17:39:37","AP01SDTM":"2020-08-08 03:10:13","AP01EDTM":"2021-02-17 11:39:37","AP02SDTM":"2021-02-17 11:39:37","AP02EDTM":"2022-02-17 17:39:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":559,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2671,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04024,"AVALU":"g/L","BASE2":2.75457,"BASE":3.04024,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.28567,"PCHG2":10.37073,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2020-08-23 03:10:13","ADY":15,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-133","SUBJID":"id-133","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.31712,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-08 03:10:13","TRTEDTM":"2022-02-17 17:39:37","TRT01SDTM":"2020-08-08 03:10:13","TRT01EDTM":"2021-02-17 11:39:37","TRT02SDTM":"2021-02-17 11:39:37","TRT02EDTM":"2022-02-17 17:39:37","AP01SDTM":"2020-08-08 03:10:13","AP01EDTM":"2021-02-17 11:39:37","AP02SDTM":"2021-02-17 11:39:37","AP02EDTM":"2022-02-17 17:39:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":559,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2109,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85918,"AVALU":"g/L","BASE2":2.75457,"BASE":3.04024,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10462,"PCHG2":3.7979,"CHG":-0.18105,"PCHG":-5.95523,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2020-10-03 03:10:13","ADY":56,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-133","SUBJID":"id-133","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.31712,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-08 03:10:13","TRTEDTM":"2022-02-17 17:39:37","TRT01SDTM":"2020-08-08 03:10:13","TRT01EDTM":"2021-02-17 11:39:37","TRT02SDTM":"2021-02-17 11:39:37","TRT02EDTM":"2022-02-17 17:39:37","AP01SDTM":"2020-08-08 03:10:13","AP01EDTM":"2021-02-17 11:39:37","AP02SDTM":"2021-02-17 11:39:37","AP02EDTM":"2022-02-17 17:39:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":559,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7623,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80033,"AVALU":"g/L","BASE2":2.75457,"BASE":3.04024,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04576,"PCHG2":1.66127,"CHG":-0.23991,"PCHG":-7.8911,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2020-12-13 03:10:13","ADY":127,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-133","SUBJID":"id-133","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.31712,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-08 03:10:13","TRTEDTM":"2022-02-17 17:39:37","TRT01SDTM":"2020-08-08 03:10:13","TRT01EDTM":"2021-02-17 11:39:37","TRT02SDTM":"2021-02-17 11:39:37","TRT02EDTM":"2022-02-17 17:39:37","AP01SDTM":"2020-08-08 03:10:13","AP01EDTM":"2021-02-17 11:39:37","AP02SDTM":"2021-02-17 11:39:37","AP02EDTM":"2022-02-17 17:39:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":559,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6545,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95679,"AVALU":"g/L","BASE2":2.75457,"BASE":3.04024,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.20222,"PCHG2":7.34124,"CHG":-0.08345,"PCHG":-2.74484,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-02-21 03:10:13","ADY":197,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-133","SUBJID":"id-133","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.31712,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-08 03:10:13","TRTEDTM":"2022-02-17 17:39:37","TRT01SDTM":"2020-08-08 03:10:13","TRT01EDTM":"2021-02-17 11:39:37","TRT02SDTM":"2021-02-17 11:39:37","TRT02EDTM":"2022-02-17 17:39:37","AP01SDTM":"2020-08-08 03:10:13","AP01EDTM":"2021-02-17 11:39:37","AP02SDTM":"2021-02-17 11:39:37","AP02EDTM":"2022-02-17 17:39:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":559,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3590,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84714,"AVALU":"g/L","BASE2":2.75457,"BASE":3.04024,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09257,"PCHG2":3.36068,"CHG":-0.1931,"PCHG":-6.35137,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-08-13 03:10:13","ADY":370,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-133","SUBJID":"id-133","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.31712,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-08 03:10:13","TRTEDTM":"2022-02-17 17:39:37","TRT01SDTM":"2020-08-08 03:10:13","TRT01EDTM":"2021-02-17 11:39:37","TRT02SDTM":"2021-02-17 11:39:37","TRT02EDTM":"2022-02-17 17:39:37","AP01SDTM":"2020-08-08 03:10:13","AP01EDTM":"2021-02-17 11:39:37","AP02SDTM":"2021-02-17 11:39:37","AP02EDTM":"2022-02-17 17:39:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":559,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5983,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92431,"AVALU":"g/L","BASE2":2.75457,"BASE":3.04024,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16974,"PCHG2":6.16218,"CHG":-0.11593,"PCHG":-3.81311,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-12-23 03:10:13","ADY":502,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-144","SUBJID":"id-144","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.10856,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-16","TRTSDTM":"2020-02-19 20:29:48","TRTEDTM":"2022-02-19 09:43:45","TRT01SDTM":"2020-02-19 20:29:48","TRT01EDTM":"2021-02-19 03:43:45","TRT02SDTM":"2021-02-19 03:43:45","TRT02EDTM":"2022-02-19 09:43:45","AP01SDTM":"2020-02-19 20:29:48","AP01EDTM":"2021-02-19 03:43:45","AP02SDTM":"2021-02-19 03:43:45","AP02EDTM":"2022-02-19 09:43:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":731,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-04","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5512,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.09402,"AVALU":"U/L","BASE2":22.09402,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-17 20:29:48","ADY":241,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-144","SUBJID":"id-144","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.10856,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-16","TRTSDTM":"2020-02-19 20:29:48","TRTEDTM":"2022-02-19 09:43:45","TRT01SDTM":"2020-02-19 20:29:48","TRT01EDTM":"2021-02-19 03:43:45","TRT02SDTM":"2021-02-19 03:43:45","TRT02EDTM":"2022-02-19 09:43:45","AP01SDTM":"2020-02-19 20:29:48","AP01EDTM":"2021-02-19 03:43:45","AP02SDTM":"2021-02-19 03:43:45","AP02EDTM":"2022-02-19 09:43:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":731,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-04","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2273,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.46881,"AVALU":"U/L","BASE2":22.09402,"BASE":33.46881,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":11.37479,"PCHG2":51.48359,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-20 20:29:48","ADY":244,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-144","SUBJID":"id-144","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.10856,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-16","TRTSDTM":"2020-02-19 20:29:48","TRTEDTM":"2022-02-19 09:43:45","TRT01SDTM":"2020-02-19 20:29:48","TRT01EDTM":"2021-02-19 03:43:45","TRT02SDTM":"2021-02-19 03:43:45","TRT02EDTM":"2022-02-19 09:43:45","AP01SDTM":"2020-02-19 20:29:48","AP01EDTM":"2021-02-19 03:43:45","AP02SDTM":"2021-02-19 03:43:45","AP02EDTM":"2022-02-19 09:43:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":731,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-04","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4558,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.40337,"AVALU":"U/L","BASE2":22.09402,"BASE":33.46881,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.30935,"PCHG2":24.03071,"CHG":-6.06545,"PCHG":-18.12268,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-30 20:29:48","ADY":315,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-144","SUBJID":"id-144","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.10856,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-16","TRTSDTM":"2020-02-19 20:29:48","TRTEDTM":"2022-02-19 09:43:45","TRT01SDTM":"2020-02-19 20:29:48","TRT01EDTM":"2021-02-19 03:43:45","TRT02SDTM":"2021-02-19 03:43:45","TRT02EDTM":"2022-02-19 09:43:45","AP01SDTM":"2020-02-19 20:29:48","AP01EDTM":"2021-02-19 03:43:45","AP02SDTM":"2021-02-19 03:43:45","AP02EDTM":"2022-02-19 09:43:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":731,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-04","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7842,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.71901,"AVALU":"U/L","BASE2":22.09402,"BASE":33.46881,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.375,"PCHG2":-51.48454,"CHG":-22.7498,"PCHG":-67.97313,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-07 20:29:48","ADY":443,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-144","SUBJID":"id-144","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.10856,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-16","TRTSDTM":"2020-02-19 20:29:48","TRTEDTM":"2022-02-19 09:43:45","TRT01SDTM":"2020-02-19 20:29:48","TRT01EDTM":"2021-02-19 03:43:45","TRT02SDTM":"2021-02-19 03:43:45","TRT02EDTM":"2022-02-19 09:43:45","AP01SDTM":"2020-02-19 20:29:48","AP01EDTM":"2021-02-19 03:43:45","AP02SDTM":"2021-02-19 03:43:45","AP02EDTM":"2022-02-19 09:43:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":731,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-04","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2846,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.83627,"AVALU":"U/L","BASE2":22.09402,"BASE":33.46881,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-19.25775,"PCHG2":-87.16274,"CHG":-30.63255,"PCHG":-91.52564,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-07-06 20:29:48","ADY":503,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-144","SUBJID":"id-144","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.10856,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-16","TRTSDTM":"2020-02-19 20:29:48","TRTEDTM":"2022-02-19 09:43:45","TRT01SDTM":"2020-02-19 20:29:48","TRT01EDTM":"2021-02-19 03:43:45","TRT02SDTM":"2021-02-19 03:43:45","TRT02EDTM":"2022-02-19 09:43:45","AP01SDTM":"2020-02-19 20:29:48","AP01EDTM":"2021-02-19 03:43:45","AP02SDTM":"2021-02-19 03:43:45","AP02EDTM":"2022-02-19 09:43:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":731,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-04","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4459,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.74288,"AVALU":"U/L","BASE2":22.09402,"BASE":33.46881,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.35114,"PCHG2":-74.00709,"CHG":-27.72593,"PCHG":-82.84111,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-08-29 20:29:48","ADY":557,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-144","SUBJID":"id-144","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.10856,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-16","TRTSDTM":"2020-02-19 20:29:48","TRTEDTM":"2022-02-19 09:43:45","TRT01SDTM":"2020-02-19 20:29:48","TRT01EDTM":"2021-02-19 03:43:45","TRT02SDTM":"2021-02-19 03:43:45","TRT02EDTM":"2022-02-19 09:43:45","AP01SDTM":"2020-02-19 20:29:48","AP01EDTM":"2021-02-19 03:43:45","AP02SDTM":"2021-02-19 03:43:45","AP02EDTM":"2022-02-19 09:43:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":731,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-04","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7179,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.91771,"AVALU":"U/L","BASE2":22.09402,"BASE":33.46881,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.82369,"PCHG2":12.78034,"CHG":-8.55111,"PCHG":-25.54947,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-14 20:29:48","ADY":634,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-144","SUBJID":"id-144","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.10856,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-16","TRTSDTM":"2020-02-19 20:29:48","TRTEDTM":"2022-02-19 09:43:45","TRT01SDTM":"2020-02-19 20:29:48","TRT01EDTM":"2021-02-19 03:43:45","TRT02SDTM":"2021-02-19 03:43:45","TRT02EDTM":"2022-02-19 09:43:45","AP01SDTM":"2020-02-19 20:29:48","AP01EDTM":"2021-02-19 03:43:45","AP02SDTM":"2021-02-19 03:43:45","AP02EDTM":"2022-02-19 09:43:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":731,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-04","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3730,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.78288,"AVALU":"mg/L","BASE2":7.78288,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-10-17 20:29:48","ADY":241,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-144","SUBJID":"id-144","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.10856,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-16","TRTSDTM":"2020-02-19 20:29:48","TRTEDTM":"2022-02-19 09:43:45","TRT01SDTM":"2020-02-19 20:29:48","TRT01EDTM":"2021-02-19 03:43:45","TRT02SDTM":"2021-02-19 03:43:45","TRT02EDTM":"2022-02-19 09:43:45","AP01SDTM":"2020-02-19 20:29:48","AP01EDTM":"2021-02-19 03:43:45","AP02SDTM":"2021-02-19 03:43:45","AP02EDTM":"2022-02-19 09:43:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":731,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-04","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1962,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.74263,"AVALU":"mg/L","BASE2":7.78288,"BASE":8.74263,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.95975,"PCHG2":12.33159,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-20 20:29:48","ADY":244,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-144","SUBJID":"id-144","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.10856,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-16","TRTSDTM":"2020-02-19 20:29:48","TRTEDTM":"2022-02-19 09:43:45","TRT01SDTM":"2020-02-19 20:29:48","TRT01EDTM":"2021-02-19 03:43:45","TRT02SDTM":"2021-02-19 03:43:45","TRT02EDTM":"2022-02-19 09:43:45","AP01SDTM":"2020-02-19 20:29:48","AP01EDTM":"2021-02-19 03:43:45","AP02SDTM":"2021-02-19 03:43:45","AP02EDTM":"2022-02-19 09:43:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":731,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-04","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2938,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.91849,"AVALU":"mg/L","BASE2":7.78288,"BASE":8.74263,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13561,"PCHG2":1.74241,"CHG":-0.82414,"PCHG":-9.42672,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-12-30 20:29:48","ADY":315,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-144","SUBJID":"id-144","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.10856,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-16","TRTSDTM":"2020-02-19 20:29:48","TRTEDTM":"2022-02-19 09:43:45","TRT01SDTM":"2020-02-19 20:29:48","TRT01EDTM":"2021-02-19 03:43:45","TRT02SDTM":"2021-02-19 03:43:45","TRT02EDTM":"2022-02-19 09:43:45","AP01SDTM":"2020-02-19 20:29:48","AP01EDTM":"2021-02-19 03:43:45","AP02SDTM":"2021-02-19 03:43:45","AP02EDTM":"2022-02-19 09:43:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":731,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-04","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7645,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.55057,"AVALU":"mg/L","BASE2":7.78288,"BASE":8.74263,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.76769,"PCHG2":22.71254,"CHG":0.80794,"PCHG":9.24135,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-07 20:29:48","ADY":443,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-144","SUBJID":"id-144","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.10856,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-16","TRTSDTM":"2020-02-19 20:29:48","TRTEDTM":"2022-02-19 09:43:45","TRT01SDTM":"2020-02-19 20:29:48","TRT01EDTM":"2021-02-19 03:43:45","TRT02SDTM":"2021-02-19 03:43:45","TRT02EDTM":"2022-02-19 09:43:45","AP01SDTM":"2020-02-19 20:29:48","AP01EDTM":"2021-02-19 03:43:45","AP02SDTM":"2021-02-19 03:43:45","AP02EDTM":"2022-02-19 09:43:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":731,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-04","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4636,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.02016,"AVALU":"mg/L","BASE2":7.78288,"BASE":8.74263,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.23728,"PCHG2":15.89747,"CHG":0.27753,"PCHG":3.17442,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-06 20:29:48","ADY":503,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-144","SUBJID":"id-144","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.10856,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-16","TRTSDTM":"2020-02-19 20:29:48","TRTEDTM":"2022-02-19 09:43:45","TRT01SDTM":"2020-02-19 20:29:48","TRT01EDTM":"2021-02-19 03:43:45","TRT02SDTM":"2021-02-19 03:43:45","TRT02EDTM":"2022-02-19 09:43:45","AP01SDTM":"2020-02-19 20:29:48","AP01EDTM":"2021-02-19 03:43:45","AP02SDTM":"2021-02-19 03:43:45","AP02EDTM":"2022-02-19 09:43:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":731,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-04","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8014,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.78609,"AVALU":"mg/L","BASE2":7.78288,"BASE":8.74263,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.00321,"PCHG2":12.88997,"CHG":0.04346,"PCHG":0.49709,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-29 20:29:48","ADY":557,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-144","SUBJID":"id-144","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.10856,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-16","TRTSDTM":"2020-02-19 20:29:48","TRTEDTM":"2022-02-19 09:43:45","TRT01SDTM":"2020-02-19 20:29:48","TRT01EDTM":"2021-02-19 03:43:45","TRT02SDTM":"2021-02-19 03:43:45","TRT02EDTM":"2022-02-19 09:43:45","AP01SDTM":"2020-02-19 20:29:48","AP01EDTM":"2021-02-19 03:43:45","AP02SDTM":"2021-02-19 03:43:45","AP02EDTM":"2022-02-19 09:43:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":731,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-04","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5930,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.41899,"AVALU":"mg/L","BASE2":7.78288,"BASE":8.74263,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.63611,"PCHG2":8.17322,"CHG":-0.32364,"PCHG":-3.70187,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-14 20:29:48","ADY":634,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-144","SUBJID":"id-144","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.10856,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-16","TRTSDTM":"2020-02-19 20:29:48","TRTEDTM":"2022-02-19 09:43:45","TRT01SDTM":"2020-02-19 20:29:48","TRT01EDTM":"2021-02-19 03:43:45","TRT02SDTM":"2021-02-19 03:43:45","TRT02EDTM":"2022-02-19 09:43:45","AP01SDTM":"2020-02-19 20:29:48","AP01EDTM":"2021-02-19 03:43:45","AP02SDTM":"2021-02-19 03:43:45","AP02EDTM":"2022-02-19 09:43:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":731,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-04","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7477,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94388,"AVALU":"g/L","BASE2":2.94388,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-17 20:29:48","ADY":241,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-144","SUBJID":"id-144","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.10856,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-16","TRTSDTM":"2020-02-19 20:29:48","TRTEDTM":"2022-02-19 09:43:45","TRT01SDTM":"2020-02-19 20:29:48","TRT01EDTM":"2021-02-19 03:43:45","TRT02SDTM":"2021-02-19 03:43:45","TRT02EDTM":"2022-02-19 09:43:45","AP01SDTM":"2020-02-19 20:29:48","AP01EDTM":"2021-02-19 03:43:45","AP02SDTM":"2021-02-19 03:43:45","AP02EDTM":"2022-02-19 09:43:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":731,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-04","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5684,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.69223,"AVALU":"g/L","BASE2":2.94388,"BASE":2.69223,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.25165,"PCHG2":-8.54833,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-20 20:29:48","ADY":244,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-144","SUBJID":"id-144","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.10856,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-16","TRTSDTM":"2020-02-19 20:29:48","TRTEDTM":"2022-02-19 09:43:45","TRT01SDTM":"2020-02-19 20:29:48","TRT01EDTM":"2021-02-19 03:43:45","TRT02SDTM":"2021-02-19 03:43:45","TRT02EDTM":"2022-02-19 09:43:45","AP01SDTM":"2020-02-19 20:29:48","AP01EDTM":"2021-02-19 03:43:45","AP02SDTM":"2021-02-19 03:43:45","AP02EDTM":"2022-02-19 09:43:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":731,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-04","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3588,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78722,"AVALU":"g/L","BASE2":2.94388,"BASE":2.69223,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15666,"PCHG2":-5.32147,"CHG":0.09499,"PCHG":3.52848,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-30 20:29:48","ADY":315,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-144","SUBJID":"id-144","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.10856,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-16","TRTSDTM":"2020-02-19 20:29:48","TRTEDTM":"2022-02-19 09:43:45","TRT01SDTM":"2020-02-19 20:29:48","TRT01EDTM":"2021-02-19 03:43:45","TRT02SDTM":"2021-02-19 03:43:45","TRT02EDTM":"2022-02-19 09:43:45","AP01SDTM":"2020-02-19 20:29:48","AP01EDTM":"2021-02-19 03:43:45","AP02SDTM":"2021-02-19 03:43:45","AP02EDTM":"2022-02-19 09:43:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":731,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-04","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1695,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04125,"AVALU":"g/L","BASE2":2.94388,"BASE":2.69223,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09737,"PCHG2":3.30763,"CHG":0.34903,"PCHG":12.96418,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-05-07 20:29:48","ADY":443,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-144","SUBJID":"id-144","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.10856,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-16","TRTSDTM":"2020-02-19 20:29:48","TRTEDTM":"2022-02-19 09:43:45","TRT01SDTM":"2020-02-19 20:29:48","TRT01EDTM":"2021-02-19 03:43:45","TRT02SDTM":"2021-02-19 03:43:45","TRT02EDTM":"2022-02-19 09:43:45","AP01SDTM":"2020-02-19 20:29:48","AP01EDTM":"2021-02-19 03:43:45","AP02SDTM":"2021-02-19 03:43:45","AP02EDTM":"2022-02-19 09:43:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":731,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-04","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1901,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9538,"AVALU":"g/L","BASE2":2.94388,"BASE":2.69223,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00992,"PCHG2":0.33691,"CHG":0.26157,"PCHG":9.71578,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-06 20:29:48","ADY":503,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-144","SUBJID":"id-144","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.10856,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-16","TRTSDTM":"2020-02-19 20:29:48","TRTEDTM":"2022-02-19 09:43:45","TRT01SDTM":"2020-02-19 20:29:48","TRT01EDTM":"2021-02-19 03:43:45","TRT02SDTM":"2021-02-19 03:43:45","TRT02EDTM":"2022-02-19 09:43:45","AP01SDTM":"2020-02-19 20:29:48","AP01EDTM":"2021-02-19 03:43:45","AP02SDTM":"2021-02-19 03:43:45","AP02EDTM":"2022-02-19 09:43:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":731,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-04","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4808,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93921,"AVALU":"g/L","BASE2":2.94388,"BASE":2.69223,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00467,"PCHG2":-0.15872,"CHG":0.24698,"PCHG":9.17382,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-29 20:29:48","ADY":557,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-144","SUBJID":"id-144","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.10856,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-16","TRTSDTM":"2020-02-19 20:29:48","TRTEDTM":"2022-02-19 09:43:45","TRT01SDTM":"2020-02-19 20:29:48","TRT01EDTM":"2021-02-19 03:43:45","TRT02SDTM":"2021-02-19 03:43:45","TRT02EDTM":"2022-02-19 09:43:45","AP01SDTM":"2020-02-19 20:29:48","AP01EDTM":"2021-02-19 03:43:45","AP02SDTM":"2021-02-19 03:43:45","AP02EDTM":"2022-02-19 09:43:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":731,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-04","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":127,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91966,"AVALU":"g/L","BASE2":2.94388,"BASE":2.69223,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02423,"PCHG2":-0.8229,"CHG":0.22743,"PCHG":8.44755,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-14 20:29:48","ADY":634,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-156","SUBJID":"id-156","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.72875,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-05","TRTSDTM":"2020-09-06 11:11:20","TRTEDTM":"2022-02-16 10:37:51","TRT01SDTM":"2020-09-06 11:11:20","TRT01EDTM":"2021-02-16 04:37:51","TRT02SDTM":"2021-02-16 04:37:51","TRT02EDTM":"2022-02-16 10:37:51","AP01SDTM":"2020-09-06 11:11:20","AP01EDTM":"2021-02-16 04:37:51","AP02SDTM":"2021-02-16 04:37:51","AP02EDTM":"2022-02-16 10:37:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":528,"DCSREAS":"DEATH","DTHDT":"2022-03-03","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-03","DTHADY":542,"ADTHAUT":"No","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3158,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.67221,"AVALU":"U/L","BASE2":23.67221,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-07 11:11:20","ADY":1,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-156","SUBJID":"id-156","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.72875,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-05","TRTSDTM":"2020-09-06 11:11:20","TRTEDTM":"2022-02-16 10:37:51","TRT01SDTM":"2020-09-06 11:11:20","TRT01EDTM":"2021-02-16 04:37:51","TRT02SDTM":"2021-02-16 04:37:51","TRT02EDTM":"2022-02-16 10:37:51","AP01SDTM":"2020-09-06 11:11:20","AP01EDTM":"2021-02-16 04:37:51","AP02SDTM":"2021-02-16 04:37:51","AP02EDTM":"2022-02-16 10:37:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":528,"DCSREAS":"DEATH","DTHDT":"2022-03-03","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-03","DTHADY":542,"ADTHAUT":"No","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7233,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.29208,"AVALU":"U/L","BASE2":23.67221,"BASE":31.29208,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":7.61987,"PCHG2":32.18911,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-17 11:11:20","ADY":192,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-156","SUBJID":"id-156","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.72875,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-05","TRTSDTM":"2020-09-06 11:11:20","TRTEDTM":"2022-02-16 10:37:51","TRT01SDTM":"2020-09-06 11:11:20","TRT01EDTM":"2021-02-16 04:37:51","TRT02SDTM":"2021-02-16 04:37:51","TRT02EDTM":"2022-02-16 10:37:51","AP01SDTM":"2020-09-06 11:11:20","AP01EDTM":"2021-02-16 04:37:51","AP02SDTM":"2021-02-16 04:37:51","AP02EDTM":"2022-02-16 10:37:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":528,"DCSREAS":"DEATH","DTHDT":"2022-03-03","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-03","DTHADY":542,"ADTHAUT":"No","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4716,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.97789,"AVALU":"U/L","BASE2":23.67221,"BASE":31.29208,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.69432,"PCHG2":-15.60614,"CHG":-11.31419,"PCHG":-36.15672,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-07 11:11:20","ADY":213,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-156","SUBJID":"id-156","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.72875,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-05","TRTSDTM":"2020-09-06 11:11:20","TRTEDTM":"2022-02-16 10:37:51","TRT01SDTM":"2020-09-06 11:11:20","TRT01EDTM":"2021-02-16 04:37:51","TRT02SDTM":"2021-02-16 04:37:51","TRT02EDTM":"2022-02-16 10:37:51","AP01SDTM":"2020-09-06 11:11:20","AP01EDTM":"2021-02-16 04:37:51","AP02SDTM":"2021-02-16 04:37:51","AP02EDTM":"2022-02-16 10:37:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":528,"DCSREAS":"DEATH","DTHDT":"2022-03-03","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-03","DTHADY":542,"ADTHAUT":"No","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3570,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.97043,"AVALU":"U/L","BASE2":23.67221,"BASE":31.29208,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.70178,"PCHG2":-2.96459,"CHG":-8.32166,"PCHG":-26.59349,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-12 11:11:20","ADY":248,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-156","SUBJID":"id-156","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.72875,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-05","TRTSDTM":"2020-09-06 11:11:20","TRTEDTM":"2022-02-16 10:37:51","TRT01SDTM":"2020-09-06 11:11:20","TRT01EDTM":"2021-02-16 04:37:51","TRT02SDTM":"2021-02-16 04:37:51","TRT02EDTM":"2022-02-16 10:37:51","AP01SDTM":"2020-09-06 11:11:20","AP01EDTM":"2021-02-16 04:37:51","AP02SDTM":"2021-02-16 04:37:51","AP02EDTM":"2022-02-16 10:37:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":528,"DCSREAS":"DEATH","DTHDT":"2022-03-03","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-03","DTHADY":542,"ADTHAUT":"No","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7633,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.88839,"AVALU":"U/L","BASE2":23.67221,"BASE":31.29208,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.78382,"PCHG2":-37.10605,"CHG":-16.40369,"PCHG":-52.42123,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-21 11:11:20","ADY":288,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-156","SUBJID":"id-156","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.72875,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-05","TRTSDTM":"2020-09-06 11:11:20","TRTEDTM":"2022-02-16 10:37:51","TRT01SDTM":"2020-09-06 11:11:20","TRT01EDTM":"2021-02-16 04:37:51","TRT02SDTM":"2021-02-16 04:37:51","TRT02EDTM":"2022-02-16 10:37:51","AP01SDTM":"2020-09-06 11:11:20","AP01EDTM":"2021-02-16 04:37:51","AP02SDTM":"2021-02-16 04:37:51","AP02EDTM":"2022-02-16 10:37:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":528,"DCSREAS":"DEATH","DTHDT":"2022-03-03","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-03","DTHADY":542,"ADTHAUT":"No","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7413,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":43.64266,"AVALU":"U/L","BASE2":23.67221,"BASE":31.29208,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.97045,"PCHG2":84.36241,"CHG":12.35057,"PCHG":39.46868,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-14 11:11:20","ADY":403,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-156","SUBJID":"id-156","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.72875,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-05","TRTSDTM":"2020-09-06 11:11:20","TRTEDTM":"2022-02-16 10:37:51","TRT01SDTM":"2020-09-06 11:11:20","TRT01EDTM":"2021-02-16 04:37:51","TRT02SDTM":"2021-02-16 04:37:51","TRT02EDTM":"2022-02-16 10:37:51","AP01SDTM":"2020-09-06 11:11:20","AP01EDTM":"2021-02-16 04:37:51","AP02SDTM":"2021-02-16 04:37:51","AP02EDTM":"2022-02-16 10:37:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":528,"DCSREAS":"DEATH","DTHDT":"2022-03-03","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-03","DTHADY":542,"ADTHAUT":"No","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6426,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.40345,"AVALU":"U/L","BASE2":23.67221,"BASE":31.29208,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.26876,"PCHG2":-22.25715,"CHG":-12.88863,"PCHG":-41.18816,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-05 11:11:20","ADY":455,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-156","SUBJID":"id-156","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.72875,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-05","TRTSDTM":"2020-09-06 11:11:20","TRTEDTM":"2022-02-16 10:37:51","TRT01SDTM":"2020-09-06 11:11:20","TRT01EDTM":"2021-02-16 04:37:51","TRT02SDTM":"2021-02-16 04:37:51","TRT02EDTM":"2022-02-16 10:37:51","AP01SDTM":"2020-09-06 11:11:20","AP01EDTM":"2021-02-16 04:37:51","AP02SDTM":"2021-02-16 04:37:51","AP02EDTM":"2022-02-16 10:37:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":528,"DCSREAS":"DEATH","DTHDT":"2022-03-03","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-03","DTHADY":542,"ADTHAUT":"No","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4829,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.8514,"AVALU":"mg/L","BASE2":8.8514,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-09-07 11:11:20","ADY":1,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-156","SUBJID":"id-156","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.72875,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-05","TRTSDTM":"2020-09-06 11:11:20","TRTEDTM":"2022-02-16 10:37:51","TRT01SDTM":"2020-09-06 11:11:20","TRT01EDTM":"2021-02-16 04:37:51","TRT02SDTM":"2021-02-16 04:37:51","TRT02EDTM":"2022-02-16 10:37:51","AP01SDTM":"2020-09-06 11:11:20","AP01EDTM":"2021-02-16 04:37:51","AP02SDTM":"2021-02-16 04:37:51","AP02EDTM":"2022-02-16 10:37:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":528,"DCSREAS":"DEATH","DTHDT":"2022-03-03","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-03","DTHADY":542,"ADTHAUT":"No","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2074,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.77637,"AVALU":"mg/L","BASE2":8.8514,"BASE":7.77637,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.07503,"PCHG2":-12.14532,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2021-03-17 11:11:20","ADY":192,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-156","SUBJID":"id-156","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.72875,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-05","TRTSDTM":"2020-09-06 11:11:20","TRTEDTM":"2022-02-16 10:37:51","TRT01SDTM":"2020-09-06 11:11:20","TRT01EDTM":"2021-02-16 04:37:51","TRT02SDTM":"2021-02-16 04:37:51","TRT02EDTM":"2022-02-16 10:37:51","AP01SDTM":"2020-09-06 11:11:20","AP01EDTM":"2021-02-16 04:37:51","AP02SDTM":"2021-02-16 04:37:51","AP02EDTM":"2022-02-16 10:37:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":528,"DCSREAS":"DEATH","DTHDT":"2022-03-03","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-03","DTHADY":542,"ADTHAUT":"No","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":559,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.79816,"AVALU":"mg/L","BASE2":8.8514,"BASE":7.77637,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05324,"PCHG2":-0.6015,"CHG":1.02179,"PCHG":13.13968,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-04-07 11:11:20","ADY":213,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-156","SUBJID":"id-156","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.72875,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-05","TRTSDTM":"2020-09-06 11:11:20","TRTEDTM":"2022-02-16 10:37:51","TRT01SDTM":"2020-09-06 11:11:20","TRT01EDTM":"2021-02-16 04:37:51","TRT02SDTM":"2021-02-16 04:37:51","TRT02EDTM":"2022-02-16 10:37:51","AP01SDTM":"2020-09-06 11:11:20","AP01EDTM":"2021-02-16 04:37:51","AP02SDTM":"2021-02-16 04:37:51","AP02EDTM":"2022-02-16 10:37:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":528,"DCSREAS":"DEATH","DTHDT":"2022-03-03","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-03","DTHADY":542,"ADTHAUT":"No","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2794,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.82132,"AVALU":"mg/L","BASE2":8.8514,"BASE":7.77637,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.03008,"PCHG2":-11.63748,"CHG":0.04495,"PCHG":0.57805,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-2","ADTM":"2021-05-12 11:11:20","ADY":248,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-156","SUBJID":"id-156","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.72875,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-05","TRTSDTM":"2020-09-06 11:11:20","TRTEDTM":"2022-02-16 10:37:51","TRT01SDTM":"2020-09-06 11:11:20","TRT01EDTM":"2021-02-16 04:37:51","TRT02SDTM":"2021-02-16 04:37:51","TRT02EDTM":"2022-02-16 10:37:51","AP01SDTM":"2020-09-06 11:11:20","AP01EDTM":"2021-02-16 04:37:51","AP02SDTM":"2021-02-16 04:37:51","AP02EDTM":"2022-02-16 10:37:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":528,"DCSREAS":"DEATH","DTHDT":"2022-03-03","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-03","DTHADY":542,"ADTHAUT":"No","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":865,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.60758,"AVALU":"mg/L","BASE2":8.8514,"BASE":7.77637,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.75618,"PCHG2":8.543,"CHG":1.83121,"PCHG":23.54835,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-06-21 11:11:20","ADY":288,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-156","SUBJID":"id-156","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.72875,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-05","TRTSDTM":"2020-09-06 11:11:20","TRTEDTM":"2022-02-16 10:37:51","TRT01SDTM":"2020-09-06 11:11:20","TRT01EDTM":"2021-02-16 04:37:51","TRT02SDTM":"2021-02-16 04:37:51","TRT02EDTM":"2022-02-16 10:37:51","AP01SDTM":"2020-09-06 11:11:20","AP01EDTM":"2021-02-16 04:37:51","AP02SDTM":"2021-02-16 04:37:51","AP02EDTM":"2022-02-16 10:37:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":528,"DCSREAS":"DEATH","DTHDT":"2022-03-03","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-03","DTHADY":542,"ADTHAUT":"No","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4680,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.55295,"AVALU":"mg/L","BASE2":8.8514,"BASE":7.77637,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.70155,"PCHG2":7.92584,"CHG":1.77658,"PCHG":22.84587,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-10-14 11:11:20","ADY":403,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-156","SUBJID":"id-156","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.72875,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-05","TRTSDTM":"2020-09-06 11:11:20","TRTEDTM":"2022-02-16 10:37:51","TRT01SDTM":"2020-09-06 11:11:20","TRT01EDTM":"2021-02-16 04:37:51","TRT02SDTM":"2021-02-16 04:37:51","TRT02EDTM":"2022-02-16 10:37:51","AP01SDTM":"2020-09-06 11:11:20","AP01EDTM":"2021-02-16 04:37:51","AP02SDTM":"2021-02-16 04:37:51","AP02EDTM":"2022-02-16 10:37:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":528,"DCSREAS":"DEATH","DTHDT":"2022-03-03","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-03","DTHADY":542,"ADTHAUT":"No","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3801,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.35632,"AVALU":"mg/L","BASE2":8.8514,"BASE":7.77637,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.50492,"PCHG2":5.70437,"CHG":1.57995,"PCHG":20.3173,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-12-05 11:11:20","ADY":455,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-156","SUBJID":"id-156","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.72875,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-05","TRTSDTM":"2020-09-06 11:11:20","TRTEDTM":"2022-02-16 10:37:51","TRT01SDTM":"2020-09-06 11:11:20","TRT01EDTM":"2021-02-16 04:37:51","TRT02SDTM":"2021-02-16 04:37:51","TRT02EDTM":"2022-02-16 10:37:51","AP01SDTM":"2020-09-06 11:11:20","AP01EDTM":"2021-02-16 04:37:51","AP02SDTM":"2021-02-16 04:37:51","AP02EDTM":"2022-02-16 10:37:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":528,"DCSREAS":"DEATH","DTHDT":"2022-03-03","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-03","DTHADY":542,"ADTHAUT":"No","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8312,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.08164,"AVALU":"g/L","BASE2":3.08164,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2020-09-07 11:11:20","ADY":1,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-156","SUBJID":"id-156","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.72875,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-05","TRTSDTM":"2020-09-06 11:11:20","TRTEDTM":"2022-02-16 10:37:51","TRT01SDTM":"2020-09-06 11:11:20","TRT01EDTM":"2021-02-16 04:37:51","TRT02SDTM":"2021-02-16 04:37:51","TRT02EDTM":"2022-02-16 10:37:51","AP01SDTM":"2020-09-06 11:11:20","AP01EDTM":"2021-02-16 04:37:51","AP02SDTM":"2021-02-16 04:37:51","AP02EDTM":"2022-02-16 10:37:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":528,"DCSREAS":"DEATH","DTHDT":"2022-03-03","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-03","DTHADY":542,"ADTHAUT":"No","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1431,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01099,"AVALU":"g/L","BASE2":3.08164,"BASE":3.01099,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.07064,"PCHG2":-2.29238,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2021-03-17 11:11:20","ADY":192,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-156","SUBJID":"id-156","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.72875,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-05","TRTSDTM":"2020-09-06 11:11:20","TRTEDTM":"2022-02-16 10:37:51","TRT01SDTM":"2020-09-06 11:11:20","TRT01EDTM":"2021-02-16 04:37:51","TRT02SDTM":"2021-02-16 04:37:51","TRT02EDTM":"2022-02-16 10:37:51","AP01SDTM":"2020-09-06 11:11:20","AP01EDTM":"2021-02-16 04:37:51","AP02SDTM":"2021-02-16 04:37:51","AP02EDTM":"2022-02-16 10:37:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":528,"DCSREAS":"DEATH","DTHDT":"2022-03-03","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-03","DTHADY":542,"ADTHAUT":"No","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2115,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00476,"AVALU":"g/L","BASE2":3.08164,"BASE":3.01099,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07688,"PCHG2":-2.49465,"CHG":-0.00623,"PCHG":-0.20702,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"4","BTOXGR":"3","ADTM":"2021-04-07 11:11:20","ADY":213,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-156","SUBJID":"id-156","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.72875,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-05","TRTSDTM":"2020-09-06 11:11:20","TRTEDTM":"2022-02-16 10:37:51","TRT01SDTM":"2020-09-06 11:11:20","TRT01EDTM":"2021-02-16 04:37:51","TRT02SDTM":"2021-02-16 04:37:51","TRT02EDTM":"2022-02-16 10:37:51","AP01SDTM":"2020-09-06 11:11:20","AP01EDTM":"2021-02-16 04:37:51","AP02SDTM":"2021-02-16 04:37:51","AP02EDTM":"2022-02-16 10:37:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":528,"DCSREAS":"DEATH","DTHDT":"2022-03-03","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-03","DTHADY":542,"ADTHAUT":"No","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4202,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92394,"AVALU":"g/L","BASE2":3.08164,"BASE":3.01099,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1577,"PCHG2":-5.11734,"CHG":-0.08706,"PCHG":-2.89124,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-05-12 11:11:20","ADY":248,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-156","SUBJID":"id-156","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.72875,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-05","TRTSDTM":"2020-09-06 11:11:20","TRTEDTM":"2022-02-16 10:37:51","TRT01SDTM":"2020-09-06 11:11:20","TRT01EDTM":"2021-02-16 04:37:51","TRT02SDTM":"2021-02-16 04:37:51","TRT02EDTM":"2022-02-16 10:37:51","AP01SDTM":"2020-09-06 11:11:20","AP01EDTM":"2021-02-16 04:37:51","AP02SDTM":"2021-02-16 04:37:51","AP02EDTM":"2022-02-16 10:37:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":528,"DCSREAS":"DEATH","DTHDT":"2022-03-03","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-03","DTHADY":542,"ADTHAUT":"No","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6503,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87912,"AVALU":"g/L","BASE2":3.08164,"BASE":3.01099,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20252,"PCHG2":-6.57171,"CHG":-0.13187,"PCHG":-4.37973,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-06-21 11:11:20","ADY":288,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-156","SUBJID":"id-156","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.72875,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-05","TRTSDTM":"2020-09-06 11:11:20","TRTEDTM":"2022-02-16 10:37:51","TRT01SDTM":"2020-09-06 11:11:20","TRT01EDTM":"2021-02-16 04:37:51","TRT02SDTM":"2021-02-16 04:37:51","TRT02EDTM":"2022-02-16 10:37:51","AP01SDTM":"2020-09-06 11:11:20","AP01EDTM":"2021-02-16 04:37:51","AP02SDTM":"2021-02-16 04:37:51","AP02EDTM":"2022-02-16 10:37:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":528,"DCSREAS":"DEATH","DTHDT":"2022-03-03","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-03","DTHADY":542,"ADTHAUT":"No","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1002,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.09388,"AVALU":"g/L","BASE2":3.08164,"BASE":3.01099,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01224,"PCHG2":0.39728,"CHG":0.08289,"PCHG":2.75276,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"3","ADTM":"2021-10-14 11:11:20","ADY":403,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-156","SUBJID":"id-156","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.72875,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-05","TRTSDTM":"2020-09-06 11:11:20","TRTEDTM":"2022-02-16 10:37:51","TRT01SDTM":"2020-09-06 11:11:20","TRT01EDTM":"2021-02-16 04:37:51","TRT02SDTM":"2021-02-16 04:37:51","TRT02EDTM":"2022-02-16 10:37:51","AP01SDTM":"2020-09-06 11:11:20","AP01EDTM":"2021-02-16 04:37:51","AP02SDTM":"2021-02-16 04:37:51","AP02EDTM":"2022-02-16 10:37:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":528,"DCSREAS":"DEATH","DTHDT":"2022-03-03","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-03","DTHADY":542,"ADTHAUT":"No","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6492,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8553,"AVALU":"g/L","BASE2":3.08164,"BASE":3.01099,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.22634,"PCHG2":-7.34479,"CHG":-0.1557,"PCHG":-5.17095,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-12-05 11:11:20","ADY":455,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-16","SUBJID":"id-16","SITEID":"CHN-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.92419,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-02","TRTSDTM":"2021-01-03 15:31:17","TRTEDTM":"2024-01-04 09:31:17","TRT01SDTM":"2021-01-03 15:31:17","TRT01EDTM":"2023-01-04 03:31:17","TRT02SDTM":"2023-01-04 03:31:17","TRT02EDTM":"2024-01-04 09:31:17","AP01SDTM":"2021-01-03 15:31:17","AP01EDTM":"2023-01-04 03:31:17","AP02SDTM":"2023-01-04 03:31:17","AP02EDTM":"2024-01-04 09:31:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5505,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.54124,"AVALU":"U/L","BASE2":16.54124,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-10 15:31:17","ADY":66,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-16","SUBJID":"id-16","SITEID":"CHN-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.92419,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-02","TRTSDTM":"2021-01-03 15:31:17","TRTEDTM":"2024-01-04 09:31:17","TRT01SDTM":"2021-01-03 15:31:17","TRT01EDTM":"2023-01-04 03:31:17","TRT02SDTM":"2023-01-04 03:31:17","TRT02EDTM":"2024-01-04 09:31:17","AP01SDTM":"2021-01-03 15:31:17","AP01EDTM":"2023-01-04 03:31:17","AP02SDTM":"2023-01-04 03:31:17","AP02EDTM":"2024-01-04 09:31:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":815,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.69434,"AVALU":"U/L","BASE2":16.54124,"BASE":22.69434,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":6.1531,"PCHG2":37.19851,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-13 15:31:17","ADY":495,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-16","SUBJID":"id-16","SITEID":"CHN-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.92419,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-02","TRTSDTM":"2021-01-03 15:31:17","TRTEDTM":"2024-01-04 09:31:17","TRT01SDTM":"2021-01-03 15:31:17","TRT01EDTM":"2023-01-04 03:31:17","TRT02SDTM":"2023-01-04 03:31:17","TRT02EDTM":"2024-01-04 09:31:17","AP01SDTM":"2021-01-03 15:31:17","AP01EDTM":"2023-01-04 03:31:17","AP02SDTM":"2023-01-04 03:31:17","AP02EDTM":"2024-01-04 09:31:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4306,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.01258,"AVALU":"U/L","BASE2":16.54124,"BASE":22.69434,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.47133,"PCHG2":51.2134,"CHG":2.31824,"PCHG":10.21505,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-14 15:31:17","ADY":496,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-16","SUBJID":"id-16","SITEID":"CHN-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.92419,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-02","TRTSDTM":"2021-01-03 15:31:17","TRTEDTM":"2024-01-04 09:31:17","TRT01SDTM":"2021-01-03 15:31:17","TRT01EDTM":"2023-01-04 03:31:17","TRT02SDTM":"2023-01-04 03:31:17","TRT02EDTM":"2024-01-04 09:31:17","AP01SDTM":"2021-01-03 15:31:17","AP01EDTM":"2023-01-04 03:31:17","AP02SDTM":"2023-01-04 03:31:17","AP02EDTM":"2024-01-04 09:31:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5860,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.65797,"AVALU":"U/L","BASE2":16.54124,"BASE":22.69434,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.11673,"PCHG2":61.16061,"CHG":3.96363,"PCHG":17.46528,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-19 15:31:17","ADY":624,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-16","SUBJID":"id-16","SITEID":"CHN-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.92419,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-02","TRTSDTM":"2021-01-03 15:31:17","TRTEDTM":"2024-01-04 09:31:17","TRT01SDTM":"2021-01-03 15:31:17","TRT01EDTM":"2023-01-04 03:31:17","TRT02SDTM":"2023-01-04 03:31:17","TRT02EDTM":"2024-01-04 09:31:17","AP01SDTM":"2021-01-03 15:31:17","AP01EDTM":"2023-01-04 03:31:17","AP02SDTM":"2023-01-04 03:31:17","AP02EDTM":"2024-01-04 09:31:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7405,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.88369,"AVALU":"U/L","BASE2":16.54124,"BASE":22.69434,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.34244,"PCHG2":86.70716,"CHG":8.18935,"PCHG":36.08541,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-24 15:31:17","ADY":782,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-16","SUBJID":"id-16","SITEID":"CHN-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.92419,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-02","TRTSDTM":"2021-01-03 15:31:17","TRTEDTM":"2024-01-04 09:31:17","TRT01SDTM":"2021-01-03 15:31:17","TRT01EDTM":"2023-01-04 03:31:17","TRT02SDTM":"2023-01-04 03:31:17","TRT02EDTM":"2024-01-04 09:31:17","AP01SDTM":"2021-01-03 15:31:17","AP01EDTM":"2023-01-04 03:31:17","AP02SDTM":"2023-01-04 03:31:17","AP02EDTM":"2024-01-04 09:31:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3205,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.79242,"AVALU":"U/L","BASE2":16.54124,"BASE":22.69434,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.25118,"PCHG2":7.564,"CHG":-4.90192,"PCHG":-21.59973,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-10-22 15:31:17","ADY":1022,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-16","SUBJID":"id-16","SITEID":"CHN-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.92419,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-02","TRTSDTM":"2021-01-03 15:31:17","TRTEDTM":"2024-01-04 09:31:17","TRT01SDTM":"2021-01-03 15:31:17","TRT01EDTM":"2023-01-04 03:31:17","TRT02SDTM":"2023-01-04 03:31:17","TRT02EDTM":"2024-01-04 09:31:17","AP01SDTM":"2021-01-03 15:31:17","AP01EDTM":"2023-01-04 03:31:17","AP02SDTM":"2023-01-04 03:31:17","AP02EDTM":"2024-01-04 09:31:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2007,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.16303,"AVALU":"U/L","BASE2":16.54124,"BASE":22.69434,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.37821,"PCHG2":-50.65043,"CHG":-14.53131,"PCHG":-64.03053,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-11-05 15:31:17","ADY":1036,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-16","SUBJID":"id-16","SITEID":"CHN-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.92419,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-02","TRTSDTM":"2021-01-03 15:31:17","TRTEDTM":"2024-01-04 09:31:17","TRT01SDTM":"2021-01-03 15:31:17","TRT01EDTM":"2023-01-04 03:31:17","TRT02SDTM":"2023-01-04 03:31:17","TRT02EDTM":"2024-01-04 09:31:17","AP01SDTM":"2021-01-03 15:31:17","AP01EDTM":"2023-01-04 03:31:17","AP02SDTM":"2023-01-04 03:31:17","AP02EDTM":"2024-01-04 09:31:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2689,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.61566,"AVALU":"mg/L","BASE2":9.61566,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-03-10 15:31:17","ADY":66,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-16","SUBJID":"id-16","SITEID":"CHN-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.92419,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-02","TRTSDTM":"2021-01-03 15:31:17","TRTEDTM":"2024-01-04 09:31:17","TRT01SDTM":"2021-01-03 15:31:17","TRT01EDTM":"2023-01-04 03:31:17","TRT02SDTM":"2023-01-04 03:31:17","TRT02EDTM":"2024-01-04 09:31:17","AP01SDTM":"2021-01-03 15:31:17","AP01EDTM":"2023-01-04 03:31:17","AP02SDTM":"2023-01-04 03:31:17","AP02EDTM":"2024-01-04 09:31:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5344,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.2425,"AVALU":"mg/L","BASE2":9.61566,"BASE":6.2425,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-3.37316,"PCHG2":-35.07987,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-4","BTOXGR":"-4","ADTM":"2022-05-13 15:31:17","ADY":495,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-16","SUBJID":"id-16","SITEID":"CHN-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.92419,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-02","TRTSDTM":"2021-01-03 15:31:17","TRTEDTM":"2024-01-04 09:31:17","TRT01SDTM":"2021-01-03 15:31:17","TRT01EDTM":"2023-01-04 03:31:17","TRT02SDTM":"2023-01-04 03:31:17","TRT02EDTM":"2024-01-04 09:31:17","AP01SDTM":"2021-01-03 15:31:17","AP01EDTM":"2023-01-04 03:31:17","AP02SDTM":"2023-01-04 03:31:17","AP02EDTM":"2024-01-04 09:31:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3306,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.6368,"AVALU":"mg/L","BASE2":9.61566,"BASE":6.2425,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.97886,"PCHG2":-20.57956,"CHG":1.3943,"PCHG":22.33561,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-4","BTOXGR":"-4","ADTM":"2022-05-14 15:31:17","ADY":496,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-16","SUBJID":"id-16","SITEID":"CHN-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.92419,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-02","TRTSDTM":"2021-01-03 15:31:17","TRTEDTM":"2024-01-04 09:31:17","TRT01SDTM":"2021-01-03 15:31:17","TRT01EDTM":"2023-01-04 03:31:17","TRT02SDTM":"2023-01-04 03:31:17","TRT02EDTM":"2024-01-04 09:31:17","AP01SDTM":"2021-01-03 15:31:17","AP01EDTM":"2023-01-04 03:31:17","AP02SDTM":"2023-01-04 03:31:17","AP02EDTM":"2024-01-04 09:31:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7858,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.82866,"AVALU":"mg/L","BASE2":9.61566,"BASE":6.2425,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.78699,"PCHG2":-28.98388,"CHG":0.58617,"PCHG":9.38997,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-4","ADTM":"2022-09-19 15:31:17","ADY":624,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-16","SUBJID":"id-16","SITEID":"CHN-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.92419,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-02","TRTSDTM":"2021-01-03 15:31:17","TRTEDTM":"2024-01-04 09:31:17","TRT01SDTM":"2021-01-03 15:31:17","TRT01EDTM":"2023-01-04 03:31:17","TRT02SDTM":"2023-01-04 03:31:17","TRT02EDTM":"2024-01-04 09:31:17","AP01SDTM":"2021-01-03 15:31:17","AP01EDTM":"2023-01-04 03:31:17","AP02SDTM":"2023-01-04 03:31:17","AP02EDTM":"2024-01-04 09:31:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1667,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.25399,"AVALU":"mg/L","BASE2":9.61566,"BASE":6.2425,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.36166,"PCHG2":-3.76117,"CHG":3.0115,"PCHG":48.24188,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2023-02-24 15:31:17","ADY":782,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-16","SUBJID":"id-16","SITEID":"CHN-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.92419,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-02","TRTSDTM":"2021-01-03 15:31:17","TRTEDTM":"2024-01-04 09:31:17","TRT01SDTM":"2021-01-03 15:31:17","TRT01EDTM":"2023-01-04 03:31:17","TRT02SDTM":"2023-01-04 03:31:17","TRT02EDTM":"2024-01-04 09:31:17","AP01SDTM":"2021-01-03 15:31:17","AP01EDTM":"2023-01-04 03:31:17","AP02SDTM":"2023-01-04 03:31:17","AP02EDTM":"2024-01-04 09:31:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4291,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.7367,"AVALU":"mg/L","BASE2":9.61566,"BASE":6.2425,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.87896,"PCHG2":-9.14092,"CHG":2.4942,"PCHG":39.95516,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2023-10-22 15:31:17","ADY":1022,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-16","SUBJID":"id-16","SITEID":"CHN-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.92419,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-02","TRTSDTM":"2021-01-03 15:31:17","TRTEDTM":"2024-01-04 09:31:17","TRT01SDTM":"2021-01-03 15:31:17","TRT01EDTM":"2023-01-04 03:31:17","TRT02SDTM":"2023-01-04 03:31:17","TRT02EDTM":"2024-01-04 09:31:17","AP01SDTM":"2021-01-03 15:31:17","AP01EDTM":"2023-01-04 03:31:17","AP02SDTM":"2023-01-04 03:31:17","AP02EDTM":"2024-01-04 09:31:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3678,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.43756,"AVALU":"mg/L","BASE2":9.61566,"BASE":6.2425,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.17809,"PCHG2":-12.25184,"CHG":2.19506,"PCHG":35.16325,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2023-11-05 15:31:17","ADY":1036,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-16","SUBJID":"id-16","SITEID":"CHN-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.92419,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-02","TRTSDTM":"2021-01-03 15:31:17","TRTEDTM":"2024-01-04 09:31:17","TRT01SDTM":"2021-01-03 15:31:17","TRT01EDTM":"2023-01-04 03:31:17","TRT02SDTM":"2023-01-04 03:31:17","TRT02EDTM":"2024-01-04 09:31:17","AP01SDTM":"2021-01-03 15:31:17","AP01EDTM":"2023-01-04 03:31:17","AP02SDTM":"2023-01-04 03:31:17","AP02EDTM":"2024-01-04 09:31:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5556,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0728,"AVALU":"g/L","BASE2":3.0728,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"4","BTOXGR":"0","ADTM":"2021-03-10 15:31:17","ADY":66,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-16","SUBJID":"id-16","SITEID":"CHN-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.92419,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-02","TRTSDTM":"2021-01-03 15:31:17","TRTEDTM":"2024-01-04 09:31:17","TRT01SDTM":"2021-01-03 15:31:17","TRT01EDTM":"2023-01-04 03:31:17","TRT02SDTM":"2023-01-04 03:31:17","TRT02EDTM":"2024-01-04 09:31:17","AP01SDTM":"2021-01-03 15:31:17","AP01EDTM":"2023-01-04 03:31:17","AP02SDTM":"2023-01-04 03:31:17","AP02EDTM":"2024-01-04 09:31:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3641,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98526,"AVALU":"g/L","BASE2":3.0728,"BASE":2.98526,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.08754,"PCHG2":-2.84882,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-13 15:31:17","ADY":495,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-16","SUBJID":"id-16","SITEID":"CHN-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.92419,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-02","TRTSDTM":"2021-01-03 15:31:17","TRTEDTM":"2024-01-04 09:31:17","TRT01SDTM":"2021-01-03 15:31:17","TRT01EDTM":"2023-01-04 03:31:17","TRT02SDTM":"2023-01-04 03:31:17","TRT02EDTM":"2024-01-04 09:31:17","AP01SDTM":"2021-01-03 15:31:17","AP01EDTM":"2023-01-04 03:31:17","AP02SDTM":"2023-01-04 03:31:17","AP02EDTM":"2024-01-04 09:31:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":647,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94829,"AVALU":"g/L","BASE2":3.0728,"BASE":2.98526,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12451,"PCHG2":-4.0519,"CHG":-0.03697,"PCHG":-1.23836,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-14 15:31:17","ADY":496,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-16","SUBJID":"id-16","SITEID":"CHN-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.92419,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-02","TRTSDTM":"2021-01-03 15:31:17","TRTEDTM":"2024-01-04 09:31:17","TRT01SDTM":"2021-01-03 15:31:17","TRT01EDTM":"2023-01-04 03:31:17","TRT02SDTM":"2023-01-04 03:31:17","TRT02EDTM":"2024-01-04 09:31:17","AP01SDTM":"2021-01-03 15:31:17","AP01EDTM":"2023-01-04 03:31:17","AP02SDTM":"2023-01-04 03:31:17","AP02EDTM":"2024-01-04 09:31:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6194,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88302,"AVALU":"g/L","BASE2":3.0728,"BASE":2.98526,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18978,"PCHG2":-6.17615,"CHG":-0.10224,"PCHG":-3.4249,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-19 15:31:17","ADY":624,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-16","SUBJID":"id-16","SITEID":"CHN-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.92419,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-02","TRTSDTM":"2021-01-03 15:31:17","TRTEDTM":"2024-01-04 09:31:17","TRT01SDTM":"2021-01-03 15:31:17","TRT01EDTM":"2023-01-04 03:31:17","TRT02SDTM":"2023-01-04 03:31:17","TRT02EDTM":"2024-01-04 09:31:17","AP01SDTM":"2021-01-03 15:31:17","AP01EDTM":"2023-01-04 03:31:17","AP02SDTM":"2023-01-04 03:31:17","AP02EDTM":"2024-01-04 09:31:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3836,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74751,"AVALU":"g/L","BASE2":3.0728,"BASE":2.98526,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.32529,"PCHG2":-10.5862,"CHG":-0.23775,"PCHG":-7.96426,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-24 15:31:17","ADY":782,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-16","SUBJID":"id-16","SITEID":"CHN-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.92419,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-02","TRTSDTM":"2021-01-03 15:31:17","TRTEDTM":"2024-01-04 09:31:17","TRT01SDTM":"2021-01-03 15:31:17","TRT01EDTM":"2023-01-04 03:31:17","TRT02SDTM":"2023-01-04 03:31:17","TRT02EDTM":"2024-01-04 09:31:17","AP01SDTM":"2021-01-03 15:31:17","AP01EDTM":"2023-01-04 03:31:17","AP02SDTM":"2023-01-04 03:31:17","AP02EDTM":"2024-01-04 09:31:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3981,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77232,"AVALU":"g/L","BASE2":3.0728,"BASE":2.98526,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.30047,"PCHG2":-9.77851,"CHG":-0.21294,"PCHG":-7.1329,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-10-22 15:31:17","ADY":1022,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-16","SUBJID":"id-16","SITEID":"CHN-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.92419,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-02","TRTSDTM":"2021-01-03 15:31:17","TRTEDTM":"2024-01-04 09:31:17","TRT01SDTM":"2021-01-03 15:31:17","TRT01EDTM":"2023-01-04 03:31:17","TRT02SDTM":"2023-01-04 03:31:17","TRT02EDTM":"2024-01-04 09:31:17","AP01SDTM":"2021-01-03 15:31:17","AP01EDTM":"2023-01-04 03:31:17","AP02SDTM":"2023-01-04 03:31:17","AP02EDTM":"2024-01-04 09:31:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4649,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99181,"AVALU":"g/L","BASE2":3.0728,"BASE":2.98526,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08099,"PCHG2":-2.63577,"CHG":0.00655,"PCHG":0.2193,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-11-05 15:31:17","ADY":1036,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-163","SUBJID":"id-163","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.76362,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-27","TRTSDTM":"2020-05-27 03:46:14","TRTEDTM":"2022-02-19 06:19:03","TRT01SDTM":"2020-05-27 03:46:14","TRT01EDTM":"2021-02-19 00:19:03","TRT02SDTM":"2021-02-19 00:19:03","TRT02EDTM":"2022-02-19 06:19:03","AP01SDTM":"2020-05-27 03:46:14","AP01EDTM":"2021-02-19 00:19:03","AP02SDTM":"2021-02-19 00:19:03","AP02EDTM":"2022-02-19 06:19:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":634,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4876,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.51013,"AVALU":"U/L","BASE2":27.51013,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-23 03:46:14","ADY":57,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-163","SUBJID":"id-163","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.76362,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-27","TRTSDTM":"2020-05-27 03:46:14","TRTEDTM":"2022-02-19 06:19:03","TRT01SDTM":"2020-05-27 03:46:14","TRT01EDTM":"2021-02-19 00:19:03","TRT02SDTM":"2021-02-19 00:19:03","TRT02EDTM":"2022-02-19 06:19:03","AP01SDTM":"2020-05-27 03:46:14","AP01EDTM":"2021-02-19 00:19:03","AP02SDTM":"2021-02-19 00:19:03","AP02EDTM":"2022-02-19 06:19:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":634,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2152,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.2512,"AVALU":"U/L","BASE2":27.51013,"BASE":15.2512,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-12.25893,"PCHG2":-44.56152,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-06 03:46:14","ADY":71,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-163","SUBJID":"id-163","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.76362,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-27","TRTSDTM":"2020-05-27 03:46:14","TRTEDTM":"2022-02-19 06:19:03","TRT01SDTM":"2020-05-27 03:46:14","TRT01EDTM":"2021-02-19 00:19:03","TRT02SDTM":"2021-02-19 00:19:03","TRT02EDTM":"2022-02-19 06:19:03","AP01SDTM":"2020-05-27 03:46:14","AP01EDTM":"2021-02-19 00:19:03","AP02SDTM":"2021-02-19 00:19:03","AP02EDTM":"2022-02-19 06:19:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":634,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1843,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.99629,"AVALU":"U/L","BASE2":27.51013,"BASE":15.2512,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.51384,"PCHG2":-38.21808,"CHG":1.74509,"PCHG":11.44231,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-07 03:46:14","ADY":225,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-163","SUBJID":"id-163","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.76362,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-27","TRTSDTM":"2020-05-27 03:46:14","TRTEDTM":"2022-02-19 06:19:03","TRT01SDTM":"2020-05-27 03:46:14","TRT01EDTM":"2021-02-19 00:19:03","TRT02SDTM":"2021-02-19 00:19:03","TRT02EDTM":"2022-02-19 06:19:03","AP01SDTM":"2020-05-27 03:46:14","AP01EDTM":"2021-02-19 00:19:03","AP02SDTM":"2021-02-19 00:19:03","AP02EDTM":"2022-02-19 06:19:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":634,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2465,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.93929,"AVALU":"U/L","BASE2":27.51013,"BASE":15.2512,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.57084,"PCHG2":-49.33035,"CHG":-1.31191,"PCHG":-8.60201,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-20 03:46:14","ADY":297,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-163","SUBJID":"id-163","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.76362,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-27","TRTSDTM":"2020-05-27 03:46:14","TRTEDTM":"2022-02-19 06:19:03","TRT01SDTM":"2020-05-27 03:46:14","TRT01EDTM":"2021-02-19 00:19:03","TRT02SDTM":"2021-02-19 00:19:03","TRT02EDTM":"2022-02-19 06:19:03","AP01SDTM":"2020-05-27 03:46:14","AP01EDTM":"2021-02-19 00:19:03","AP02SDTM":"2021-02-19 00:19:03","AP02EDTM":"2022-02-19 06:19:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":634,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8291,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.34638,"AVALU":"U/L","BASE2":27.51013,"BASE":15.2512,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-27.16374,"PCHG2":-98.74089,"CHG":-14.90481,"PCHG":-97.72881,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-05-24 03:46:14","ADY":362,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-163","SUBJID":"id-163","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.76362,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-27","TRTSDTM":"2020-05-27 03:46:14","TRTEDTM":"2022-02-19 06:19:03","TRT01SDTM":"2020-05-27 03:46:14","TRT01EDTM":"2021-02-19 00:19:03","TRT02SDTM":"2021-02-19 00:19:03","TRT02EDTM":"2022-02-19 06:19:03","AP01SDTM":"2020-05-27 03:46:14","AP01EDTM":"2021-02-19 00:19:03","AP02SDTM":"2021-02-19 00:19:03","AP02EDTM":"2022-02-19 06:19:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":634,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6148,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.70849,"AVALU":"U/L","BASE2":27.51013,"BASE":15.2512,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.80164,"PCHG2":-64.70939,"CHG":-5.5427,"PCHG":-36.34274,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-19 03:46:14","ADY":541,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-163","SUBJID":"id-163","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.76362,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-27","TRTSDTM":"2020-05-27 03:46:14","TRTEDTM":"2022-02-19 06:19:03","TRT01SDTM":"2020-05-27 03:46:14","TRT01EDTM":"2021-02-19 00:19:03","TRT02SDTM":"2021-02-19 00:19:03","TRT02EDTM":"2022-02-19 06:19:03","AP01SDTM":"2020-05-27 03:46:14","AP01EDTM":"2021-02-19 00:19:03","AP02SDTM":"2021-02-19 00:19:03","AP02EDTM":"2022-02-19 06:19:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":634,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3163,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.97184,"AVALU":"U/L","BASE2":27.51013,"BASE":15.2512,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.46171,"PCHG2":23.48848,"CHG":18.72064,"PCHG":122.74869,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-17 03:46:14","ADY":569,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-163","SUBJID":"id-163","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.76362,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-27","TRTSDTM":"2020-05-27 03:46:14","TRTEDTM":"2022-02-19 06:19:03","TRT01SDTM":"2020-05-27 03:46:14","TRT01EDTM":"2021-02-19 00:19:03","TRT02SDTM":"2021-02-19 00:19:03","TRT02EDTM":"2022-02-19 06:19:03","AP01SDTM":"2020-05-27 03:46:14","AP01EDTM":"2021-02-19 00:19:03","AP02SDTM":"2021-02-19 00:19:03","AP02EDTM":"2022-02-19 06:19:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":634,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8278,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.86289,"AVALU":"mg/L","BASE2":9.86289,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-23 03:46:14","ADY":57,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-163","SUBJID":"id-163","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.76362,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-27","TRTSDTM":"2020-05-27 03:46:14","TRTEDTM":"2022-02-19 06:19:03","TRT01SDTM":"2020-05-27 03:46:14","TRT01EDTM":"2021-02-19 00:19:03","TRT02SDTM":"2021-02-19 00:19:03","TRT02EDTM":"2022-02-19 06:19:03","AP01SDTM":"2020-05-27 03:46:14","AP01EDTM":"2021-02-19 00:19:03","AP02SDTM":"2021-02-19 00:19:03","AP02EDTM":"2022-02-19 06:19:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":634,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":45,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.67553,"AVALU":"mg/L","BASE2":9.86289,"BASE":8.67553,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.18736,"PCHG2":-12.0387,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-06 03:46:14","ADY":71,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-163","SUBJID":"id-163","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.76362,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-27","TRTSDTM":"2020-05-27 03:46:14","TRTEDTM":"2022-02-19 06:19:03","TRT01SDTM":"2020-05-27 03:46:14","TRT01EDTM":"2021-02-19 00:19:03","TRT02SDTM":"2021-02-19 00:19:03","TRT02EDTM":"2022-02-19 06:19:03","AP01SDTM":"2020-05-27 03:46:14","AP01EDTM":"2021-02-19 00:19:03","AP02SDTM":"2021-02-19 00:19:03","AP02EDTM":"2022-02-19 06:19:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":634,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5748,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.46438,"AVALU":"mg/L","BASE2":9.86289,"BASE":8.67553,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.60149,"PCHG2":6.09849,"CHG":1.78885,"PCHG":20.61951,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-01-07 03:46:14","ADY":225,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-163","SUBJID":"id-163","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.76362,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-27","TRTSDTM":"2020-05-27 03:46:14","TRTEDTM":"2022-02-19 06:19:03","TRT01SDTM":"2020-05-27 03:46:14","TRT01EDTM":"2021-02-19 00:19:03","TRT02SDTM":"2021-02-19 00:19:03","TRT02EDTM":"2022-02-19 06:19:03","AP01SDTM":"2020-05-27 03:46:14","AP01EDTM":"2021-02-19 00:19:03","AP02SDTM":"2021-02-19 00:19:03","AP02EDTM":"2022-02-19 06:19:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":634,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8127,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.96126,"AVALU":"mg/L","BASE2":9.86289,"BASE":8.67553,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.90163,"PCHG2":-19.28068,"CHG":-0.71427,"PCHG":-8.23314,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-03-20 03:46:14","ADY":297,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-163","SUBJID":"id-163","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.76362,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-27","TRTSDTM":"2020-05-27 03:46:14","TRTEDTM":"2022-02-19 06:19:03","TRT01SDTM":"2020-05-27 03:46:14","TRT01EDTM":"2021-02-19 00:19:03","TRT02SDTM":"2021-02-19 00:19:03","TRT02EDTM":"2022-02-19 06:19:03","AP01SDTM":"2020-05-27 03:46:14","AP01EDTM":"2021-02-19 00:19:03","AP02SDTM":"2021-02-19 00:19:03","AP02EDTM":"2022-02-19 06:19:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":634,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3000,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.06626,"AVALU":"mg/L","BASE2":9.86289,"BASE":8.67553,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.79663,"PCHG2":-8.07703,"CHG":0.39073,"PCHG":4.50387,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-24 03:46:14","ADY":362,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-163","SUBJID":"id-163","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.76362,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-27","TRTSDTM":"2020-05-27 03:46:14","TRTEDTM":"2022-02-19 06:19:03","TRT01SDTM":"2020-05-27 03:46:14","TRT01EDTM":"2021-02-19 00:19:03","TRT02SDTM":"2021-02-19 00:19:03","TRT02EDTM":"2022-02-19 06:19:03","AP01SDTM":"2020-05-27 03:46:14","AP01EDTM":"2021-02-19 00:19:03","AP02SDTM":"2021-02-19 00:19:03","AP02EDTM":"2022-02-19 06:19:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":634,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4893,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.87798,"AVALU":"mg/L","BASE2":9.86289,"BASE":8.67553,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01509,"PCHG2":0.15299,"CHG":1.20245,"PCHG":13.86029,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-19 03:46:14","ADY":541,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-163","SUBJID":"id-163","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.76362,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-27","TRTSDTM":"2020-05-27 03:46:14","TRTEDTM":"2022-02-19 06:19:03","TRT01SDTM":"2020-05-27 03:46:14","TRT01EDTM":"2021-02-19 00:19:03","TRT02SDTM":"2021-02-19 00:19:03","TRT02EDTM":"2022-02-19 06:19:03","AP01SDTM":"2020-05-27 03:46:14","AP01EDTM":"2021-02-19 00:19:03","AP02SDTM":"2021-02-19 00:19:03","AP02EDTM":"2022-02-19 06:19:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":634,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7642,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.16996,"AVALU":"mg/L","BASE2":9.86289,"BASE":8.67553,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.69293,"PCHG2":-7.02564,"CHG":0.49443,"PCHG":5.69917,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-17 03:46:14","ADY":569,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-163","SUBJID":"id-163","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.76362,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-27","TRTSDTM":"2020-05-27 03:46:14","TRTEDTM":"2022-02-19 06:19:03","TRT01SDTM":"2020-05-27 03:46:14","TRT01EDTM":"2021-02-19 00:19:03","TRT02SDTM":"2021-02-19 00:19:03","TRT02EDTM":"2022-02-19 06:19:03","AP01SDTM":"2020-05-27 03:46:14","AP01EDTM":"2021-02-19 00:19:03","AP02SDTM":"2021-02-19 00:19:03","AP02EDTM":"2022-02-19 06:19:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":634,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4059,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96605,"AVALU":"g/L","BASE2":2.96605,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-23 03:46:14","ADY":57,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-163","SUBJID":"id-163","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.76362,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-27","TRTSDTM":"2020-05-27 03:46:14","TRTEDTM":"2022-02-19 06:19:03","TRT01SDTM":"2020-05-27 03:46:14","TRT01EDTM":"2021-02-19 00:19:03","TRT02SDTM":"2021-02-19 00:19:03","TRT02EDTM":"2022-02-19 06:19:03","AP01SDTM":"2020-05-27 03:46:14","AP01EDTM":"2021-02-19 00:19:03","AP02SDTM":"2021-02-19 00:19:03","AP02EDTM":"2022-02-19 06:19:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":634,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6719,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79682,"AVALU":"g/L","BASE2":2.96605,"BASE":2.79682,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.16923,"PCHG2":-5.70559,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-06 03:46:14","ADY":71,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-163","SUBJID":"id-163","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.76362,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-27","TRTSDTM":"2020-05-27 03:46:14","TRTEDTM":"2022-02-19 06:19:03","TRT01SDTM":"2020-05-27 03:46:14","TRT01EDTM":"2021-02-19 00:19:03","TRT02SDTM":"2021-02-19 00:19:03","TRT02EDTM":"2022-02-19 06:19:03","AP01SDTM":"2020-05-27 03:46:14","AP01EDTM":"2021-02-19 00:19:03","AP02SDTM":"2021-02-19 00:19:03","AP02EDTM":"2022-02-19 06:19:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":634,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4416,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94727,"AVALU":"g/L","BASE2":2.96605,"BASE":2.79682,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01878,"PCHG2":-0.63318,"CHG":0.15045,"PCHG":5.37933,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-07 03:46:14","ADY":225,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-163","SUBJID":"id-163","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.76362,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-27","TRTSDTM":"2020-05-27 03:46:14","TRTEDTM":"2022-02-19 06:19:03","TRT01SDTM":"2020-05-27 03:46:14","TRT01EDTM":"2021-02-19 00:19:03","TRT02SDTM":"2021-02-19 00:19:03","TRT02EDTM":"2022-02-19 06:19:03","AP01SDTM":"2020-05-27 03:46:14","AP01EDTM":"2021-02-19 00:19:03","AP02SDTM":"2021-02-19 00:19:03","AP02EDTM":"2022-02-19 06:19:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":634,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3172,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9243,"AVALU":"g/L","BASE2":2.96605,"BASE":2.79682,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04175,"PCHG2":-1.40757,"CHG":0.12748,"PCHG":4.55809,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-20 03:46:14","ADY":297,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-163","SUBJID":"id-163","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.76362,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-27","TRTSDTM":"2020-05-27 03:46:14","TRTEDTM":"2022-02-19 06:19:03","TRT01SDTM":"2020-05-27 03:46:14","TRT01EDTM":"2021-02-19 00:19:03","TRT02SDTM":"2021-02-19 00:19:03","TRT02EDTM":"2022-02-19 06:19:03","AP01SDTM":"2020-05-27 03:46:14","AP01EDTM":"2021-02-19 00:19:03","AP02SDTM":"2021-02-19 00:19:03","AP02EDTM":"2022-02-19 06:19:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":634,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":164,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00233,"AVALU":"g/L","BASE2":2.96605,"BASE":2.79682,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03628,"PCHG2":1.22333,"CHG":0.20551,"PCHG":7.34817,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-05-24 03:46:14","ADY":362,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-163","SUBJID":"id-163","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.76362,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-27","TRTSDTM":"2020-05-27 03:46:14","TRTEDTM":"2022-02-19 06:19:03","TRT01SDTM":"2020-05-27 03:46:14","TRT01EDTM":"2021-02-19 00:19:03","TRT02SDTM":"2021-02-19 00:19:03","TRT02EDTM":"2022-02-19 06:19:03","AP01SDTM":"2020-05-27 03:46:14","AP01EDTM":"2021-02-19 00:19:03","AP02SDTM":"2021-02-19 00:19:03","AP02EDTM":"2022-02-19 06:19:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":634,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3975,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8531,"AVALU":"g/L","BASE2":2.96605,"BASE":2.79682,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11295,"PCHG2":-3.80797,"CHG":0.05628,"PCHG":2.01244,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-19 03:46:14","ADY":541,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-163","SUBJID":"id-163","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.76362,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-27","TRTSDTM":"2020-05-27 03:46:14","TRTEDTM":"2022-02-19 06:19:03","TRT01SDTM":"2020-05-27 03:46:14","TRT01EDTM":"2021-02-19 00:19:03","TRT02SDTM":"2021-02-19 00:19:03","TRT02EDTM":"2022-02-19 06:19:03","AP01SDTM":"2020-05-27 03:46:14","AP01EDTM":"2021-02-19 00:19:03","AP02SDTM":"2021-02-19 00:19:03","AP02EDTM":"2022-02-19 06:19:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":634,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4379,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02925,"AVALU":"g/L","BASE2":2.96605,"BASE":2.79682,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0632,"PCHG2":2.13094,"CHG":0.23244,"PCHG":8.3107,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-12-17 03:46:14","ADY":569,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-181","SUBJID":"id-181","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.5313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-03","TRTSDTM":"2020-05-05 04:15:17","TRTEDTM":"2023-05-05 22:15:17","TRT01SDTM":"2020-05-05 04:15:17","TRT01EDTM":"2022-05-05 16:15:17","TRT02SDTM":"2022-05-05 16:15:17","TRT02EDTM":"2023-05-05 22:15:17","AP01SDTM":"2020-05-05 04:15:17","AP01EDTM":"2022-05-05 16:15:17","AP02SDTM":"2022-05-05 16:15:17","AP02EDTM":"2023-05-05 22:15:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-23","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1541,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.44329,"AVALU":"U/L","BASE2":15.44329,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-02 04:15:17","ADY":181,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-181","SUBJID":"id-181","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.5313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-03","TRTSDTM":"2020-05-05 04:15:17","TRTEDTM":"2023-05-05 22:15:17","TRT01SDTM":"2020-05-05 04:15:17","TRT01EDTM":"2022-05-05 16:15:17","TRT02SDTM":"2022-05-05 16:15:17","TRT02EDTM":"2023-05-05 22:15:17","AP01SDTM":"2020-05-05 04:15:17","AP01EDTM":"2022-05-05 16:15:17","AP02SDTM":"2022-05-05 16:15:17","AP02EDTM":"2023-05-05 22:15:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-23","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3517,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.95961,"AVALU":"U/L","BASE2":15.44329,"BASE":9.95961,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-5.48368,"PCHG2":-35.50848,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-14 04:15:17","ADY":285,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-181","SUBJID":"id-181","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.5313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-03","TRTSDTM":"2020-05-05 04:15:17","TRTEDTM":"2023-05-05 22:15:17","TRT01SDTM":"2020-05-05 04:15:17","TRT01EDTM":"2022-05-05 16:15:17","TRT02SDTM":"2022-05-05 16:15:17","TRT02EDTM":"2023-05-05 22:15:17","AP01SDTM":"2020-05-05 04:15:17","AP01EDTM":"2022-05-05 16:15:17","AP02SDTM":"2022-05-05 16:15:17","AP02EDTM":"2023-05-05 22:15:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-23","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":99,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.89894,"AVALU":"U/L","BASE2":15.44329,"BASE":9.95961,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.54436,"PCHG2":-3.52488,"CHG":4.93932,"PCHG":49.59349,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-12 04:15:17","ADY":372,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-181","SUBJID":"id-181","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.5313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-03","TRTSDTM":"2020-05-05 04:15:17","TRTEDTM":"2023-05-05 22:15:17","TRT01SDTM":"2020-05-05 04:15:17","TRT01EDTM":"2022-05-05 16:15:17","TRT02SDTM":"2022-05-05 16:15:17","TRT02EDTM":"2023-05-05 22:15:17","AP01SDTM":"2020-05-05 04:15:17","AP01EDTM":"2022-05-05 16:15:17","AP02SDTM":"2022-05-05 16:15:17","AP02EDTM":"2023-05-05 22:15:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-23","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3058,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.1564,"AVALU":"U/L","BASE2":15.44329,"BASE":9.95961,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.7131,"PCHG2":88.79649,"CHG":19.19678,"PCHG":192.74621,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-15 04:15:17","ADY":467,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-181","SUBJID":"id-181","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.5313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-03","TRTSDTM":"2020-05-05 04:15:17","TRTEDTM":"2023-05-05 22:15:17","TRT01SDTM":"2020-05-05 04:15:17","TRT01EDTM":"2022-05-05 16:15:17","TRT02SDTM":"2022-05-05 16:15:17","TRT02EDTM":"2023-05-05 22:15:17","AP01SDTM":"2020-05-05 04:15:17","AP01EDTM":"2022-05-05 16:15:17","AP02SDTM":"2022-05-05 16:15:17","AP02EDTM":"2023-05-05 22:15:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-23","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1458,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.8551,"AVALU":"U/L","BASE2":15.44329,"BASE":9.95961,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.58819,"PCHG2":-36.18522,"CHG":-0.10451,"PCHG":-1.04936,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-21 04:15:17","ADY":716,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-181","SUBJID":"id-181","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.5313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-03","TRTSDTM":"2020-05-05 04:15:17","TRTEDTM":"2023-05-05 22:15:17","TRT01SDTM":"2020-05-05 04:15:17","TRT01EDTM":"2022-05-05 16:15:17","TRT02SDTM":"2022-05-05 16:15:17","TRT02EDTM":"2023-05-05 22:15:17","AP01SDTM":"2020-05-05 04:15:17","AP01EDTM":"2022-05-05 16:15:17","AP02SDTM":"2022-05-05 16:15:17","AP02EDTM":"2023-05-05 22:15:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-23","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6984,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.66406,"AVALU":"U/L","BASE2":15.44329,"BASE":9.95961,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.77923,"PCHG2":-95.70002,"CHG":-9.29556,"PCHG":-93.33249,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-06-25 04:15:17","ADY":781,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-181","SUBJID":"id-181","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.5313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-03","TRTSDTM":"2020-05-05 04:15:17","TRTEDTM":"2023-05-05 22:15:17","TRT01SDTM":"2020-05-05 04:15:17","TRT01EDTM":"2022-05-05 16:15:17","TRT02SDTM":"2022-05-05 16:15:17","TRT02EDTM":"2023-05-05 22:15:17","AP01SDTM":"2020-05-05 04:15:17","AP01EDTM":"2022-05-05 16:15:17","AP02SDTM":"2022-05-05 16:15:17","AP02EDTM":"2023-05-05 22:15:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-23","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7470,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.01503,"AVALU":"U/L","BASE2":15.44329,"BASE":9.95961,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-15.42826,"PCHG2":-99.90268,"CHG":-9.94459,"PCHG":-99.8491,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2022-12-18 04:15:17","ADY":957,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-181","SUBJID":"id-181","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.5313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-03","TRTSDTM":"2020-05-05 04:15:17","TRTEDTM":"2023-05-05 22:15:17","TRT01SDTM":"2020-05-05 04:15:17","TRT01EDTM":"2022-05-05 16:15:17","TRT02SDTM":"2022-05-05 16:15:17","TRT02EDTM":"2023-05-05 22:15:17","AP01SDTM":"2020-05-05 04:15:17","AP01EDTM":"2022-05-05 16:15:17","AP02SDTM":"2022-05-05 16:15:17","AP02EDTM":"2023-05-05 22:15:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-23","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3300,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.17251,"AVALU":"mg/L","BASE2":8.17251,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-3","ADTM":"2020-11-02 04:15:17","ADY":181,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-181","SUBJID":"id-181","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.5313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-03","TRTSDTM":"2020-05-05 04:15:17","TRTEDTM":"2023-05-05 22:15:17","TRT01SDTM":"2020-05-05 04:15:17","TRT01EDTM":"2022-05-05 16:15:17","TRT02SDTM":"2022-05-05 16:15:17","TRT02EDTM":"2023-05-05 22:15:17","AP01SDTM":"2020-05-05 04:15:17","AP01EDTM":"2022-05-05 16:15:17","AP02SDTM":"2022-05-05 16:15:17","AP02EDTM":"2023-05-05 22:15:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-23","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8173,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.92079,"AVALU":"mg/L","BASE2":8.17251,"BASE":7.92079,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.25172,"PCHG2":-3.08006,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2021-02-14 04:15:17","ADY":285,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-181","SUBJID":"id-181","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.5313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-03","TRTSDTM":"2020-05-05 04:15:17","TRTEDTM":"2023-05-05 22:15:17","TRT01SDTM":"2020-05-05 04:15:17","TRT01EDTM":"2022-05-05 16:15:17","TRT02SDTM":"2022-05-05 16:15:17","TRT02EDTM":"2023-05-05 22:15:17","AP01SDTM":"2020-05-05 04:15:17","AP01EDTM":"2022-05-05 16:15:17","AP02SDTM":"2022-05-05 16:15:17","AP02EDTM":"2023-05-05 22:15:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-23","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1190,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.95538,"AVALU":"mg/L","BASE2":8.17251,"BASE":7.92079,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21713,"PCHG2":-2.65681,"CHG":0.03459,"PCHG":0.4367,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-2","BTOXGR":"-3","ADTM":"2021-05-12 04:15:17","ADY":372,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-181","SUBJID":"id-181","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.5313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-03","TRTSDTM":"2020-05-05 04:15:17","TRTEDTM":"2023-05-05 22:15:17","TRT01SDTM":"2020-05-05 04:15:17","TRT01EDTM":"2022-05-05 16:15:17","TRT02SDTM":"2022-05-05 16:15:17","TRT02EDTM":"2023-05-05 22:15:17","AP01SDTM":"2020-05-05 04:15:17","AP01EDTM":"2022-05-05 16:15:17","AP02SDTM":"2022-05-05 16:15:17","AP02EDTM":"2023-05-05 22:15:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-23","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":202,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.41528,"AVALU":"mg/L","BASE2":8.17251,"BASE":7.92079,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.24277,"PCHG2":15.20668,"CHG":1.49449,"PCHG":18.86789,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-08-15 04:15:17","ADY":467,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-181","SUBJID":"id-181","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.5313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-03","TRTSDTM":"2020-05-05 04:15:17","TRTEDTM":"2023-05-05 22:15:17","TRT01SDTM":"2020-05-05 04:15:17","TRT01EDTM":"2022-05-05 16:15:17","TRT02SDTM":"2022-05-05 16:15:17","TRT02EDTM":"2023-05-05 22:15:17","AP01SDTM":"2020-05-05 04:15:17","AP01EDTM":"2022-05-05 16:15:17","AP02SDTM":"2022-05-05 16:15:17","AP02EDTM":"2023-05-05 22:15:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-23","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5851,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.8331,"AVALU":"mg/L","BASE2":8.17251,"BASE":7.92079,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.66059,"PCHG2":20.31918,"CHG":1.91231,"PCHG":24.14286,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2022-04-21 04:15:17","ADY":716,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-181","SUBJID":"id-181","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.5313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-03","TRTSDTM":"2020-05-05 04:15:17","TRTEDTM":"2023-05-05 22:15:17","TRT01SDTM":"2020-05-05 04:15:17","TRT01EDTM":"2022-05-05 16:15:17","TRT02SDTM":"2022-05-05 16:15:17","TRT02EDTM":"2023-05-05 22:15:17","AP01SDTM":"2020-05-05 04:15:17","AP01EDTM":"2022-05-05 16:15:17","AP02SDTM":"2022-05-05 16:15:17","AP02EDTM":"2023-05-05 22:15:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-23","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4075,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.58784,"AVALU":"mg/L","BASE2":8.17251,"BASE":7.92079,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.41533,"PCHG2":17.31814,"CHG":1.66705,"PCHG":21.04645,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2022-06-25 04:15:17","ADY":781,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-181","SUBJID":"id-181","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.5313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-03","TRTSDTM":"2020-05-05 04:15:17","TRTEDTM":"2023-05-05 22:15:17","TRT01SDTM":"2020-05-05 04:15:17","TRT01EDTM":"2022-05-05 16:15:17","TRT02SDTM":"2022-05-05 16:15:17","TRT02EDTM":"2023-05-05 22:15:17","AP01SDTM":"2020-05-05 04:15:17","AP01EDTM":"2022-05-05 16:15:17","AP02SDTM":"2022-05-05 16:15:17","AP02EDTM":"2023-05-05 22:15:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-23","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5213,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.30411,"AVALU":"mg/L","BASE2":8.17251,"BASE":7.92079,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1316,"PCHG2":1.61027,"CHG":0.38332,"PCHG":4.83939,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2022-12-18 04:15:17","ADY":957,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-181","SUBJID":"id-181","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.5313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-03","TRTSDTM":"2020-05-05 04:15:17","TRTEDTM":"2023-05-05 22:15:17","TRT01SDTM":"2020-05-05 04:15:17","TRT01EDTM":"2022-05-05 16:15:17","TRT02SDTM":"2022-05-05 16:15:17","TRT02EDTM":"2023-05-05 22:15:17","AP01SDTM":"2020-05-05 04:15:17","AP01EDTM":"2022-05-05 16:15:17","AP02SDTM":"2022-05-05 16:15:17","AP02EDTM":"2023-05-05 22:15:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-23","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4322,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80245,"AVALU":"g/L","BASE2":2.80245,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-02 04:15:17","ADY":181,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-181","SUBJID":"id-181","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.5313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-03","TRTSDTM":"2020-05-05 04:15:17","TRTEDTM":"2023-05-05 22:15:17","TRT01SDTM":"2020-05-05 04:15:17","TRT01EDTM":"2022-05-05 16:15:17","TRT02SDTM":"2022-05-05 16:15:17","TRT02EDTM":"2023-05-05 22:15:17","AP01SDTM":"2020-05-05 04:15:17","AP01EDTM":"2022-05-05 16:15:17","AP02SDTM":"2022-05-05 16:15:17","AP02EDTM":"2023-05-05 22:15:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-23","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6049,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80244,"AVALU":"g/L","BASE2":2.80245,"BASE":2.80244,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-9.78489e-06,"PCHG2":-0.00035,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-14 04:15:17","ADY":285,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-181","SUBJID":"id-181","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.5313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-03","TRTSDTM":"2020-05-05 04:15:17","TRTEDTM":"2023-05-05 22:15:17","TRT01SDTM":"2020-05-05 04:15:17","TRT01EDTM":"2022-05-05 16:15:17","TRT02SDTM":"2022-05-05 16:15:17","TRT02EDTM":"2023-05-05 22:15:17","AP01SDTM":"2020-05-05 04:15:17","AP01EDTM":"2022-05-05 16:15:17","AP02SDTM":"2022-05-05 16:15:17","AP02EDTM":"2023-05-05 22:15:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-23","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4858,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91271,"AVALU":"g/L","BASE2":2.80245,"BASE":2.80244,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11026,"PCHG2":3.93439,"CHG":0.11027,"PCHG":3.93476,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-12 04:15:17","ADY":372,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-181","SUBJID":"id-181","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.5313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-03","TRTSDTM":"2020-05-05 04:15:17","TRTEDTM":"2023-05-05 22:15:17","TRT01SDTM":"2020-05-05 04:15:17","TRT01EDTM":"2022-05-05 16:15:17","TRT02SDTM":"2022-05-05 16:15:17","TRT02EDTM":"2023-05-05 22:15:17","AP01SDTM":"2020-05-05 04:15:17","AP01EDTM":"2022-05-05 16:15:17","AP02SDTM":"2022-05-05 16:15:17","AP02EDTM":"2023-05-05 22:15:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-23","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1963,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95973,"AVALU":"g/L","BASE2":2.80245,"BASE":2.80244,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15728,"PCHG2":5.61215,"CHG":0.15729,"PCHG":5.61252,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-15 04:15:17","ADY":467,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-181","SUBJID":"id-181","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.5313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-03","TRTSDTM":"2020-05-05 04:15:17","TRTEDTM":"2023-05-05 22:15:17","TRT01SDTM":"2020-05-05 04:15:17","TRT01EDTM":"2022-05-05 16:15:17","TRT02SDTM":"2022-05-05 16:15:17","TRT02EDTM":"2023-05-05 22:15:17","AP01SDTM":"2020-05-05 04:15:17","AP01EDTM":"2022-05-05 16:15:17","AP02SDTM":"2022-05-05 16:15:17","AP02EDTM":"2023-05-05 22:15:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-23","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4750,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84658,"AVALU":"g/L","BASE2":2.80245,"BASE":2.80244,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04413,"PCHG2":1.57487,"CHG":0.04414,"PCHG":1.57523,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-21 04:15:17","ADY":716,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-181","SUBJID":"id-181","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.5313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-03","TRTSDTM":"2020-05-05 04:15:17","TRTEDTM":"2023-05-05 22:15:17","TRT01SDTM":"2020-05-05 04:15:17","TRT01EDTM":"2022-05-05 16:15:17","TRT02SDTM":"2022-05-05 16:15:17","TRT02EDTM":"2023-05-05 22:15:17","AP01SDTM":"2020-05-05 04:15:17","AP01EDTM":"2022-05-05 16:15:17","AP02SDTM":"2022-05-05 16:15:17","AP02EDTM":"2023-05-05 22:15:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-23","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7731,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.08252,"AVALU":"g/L","BASE2":2.80245,"BASE":2.80244,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.28007,"PCHG2":9.99393,"CHG":0.28008,"PCHG":9.99432,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-06-25 04:15:17","ADY":781,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-181","SUBJID":"id-181","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.5313,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-03","TRTSDTM":"2020-05-05 04:15:17","TRTEDTM":"2023-05-05 22:15:17","TRT01SDTM":"2020-05-05 04:15:17","TRT01EDTM":"2022-05-05 16:15:17","TRT02SDTM":"2022-05-05 16:15:17","TRT02EDTM":"2023-05-05 22:15:17","AP01SDTM":"2020-05-05 04:15:17","AP01EDTM":"2022-05-05 16:15:17","AP02SDTM":"2022-05-05 16:15:17","AP02EDTM":"2023-05-05 22:15:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-23","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8395,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97439,"AVALU":"g/L","BASE2":2.80245,"BASE":2.80244,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17194,"PCHG2":6.13546,"CHG":0.17195,"PCHG":6.13583,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-18 04:15:17","ADY":957,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-186","SUBJID":"id-186","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.52118,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 19:35:51","TRTEDTM":"2024-02-03 13:35:51","TRT01SDTM":"2021-02-02 19:35:51","TRT01EDTM":"2023-02-03 07:35:51","TRT02SDTM":"2023-02-03 07:35:51","TRT02EDTM":"2024-02-03 13:35:51","AP01SDTM":"2021-02-02 19:35:51","AP01EDTM":"2023-02-03 07:35:51","AP02SDTM":"2023-02-03 07:35:51","AP02EDTM":"2024-02-03 13:35:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-18","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1377,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.92914,"AVALU":"U/L","BASE2":33.92914,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-03 19:35:51","ADY":121,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-186","SUBJID":"id-186","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.52118,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 19:35:51","TRTEDTM":"2024-02-03 13:35:51","TRT01SDTM":"2021-02-02 19:35:51","TRT01EDTM":"2023-02-03 07:35:51","TRT02SDTM":"2023-02-03 07:35:51","TRT02EDTM":"2024-02-03 13:35:51","AP01SDTM":"2021-02-02 19:35:51","AP01EDTM":"2023-02-03 07:35:51","AP02SDTM":"2023-02-03 07:35:51","AP02EDTM":"2024-02-03 13:35:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-18","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6298,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.37874,"AVALU":"U/L","BASE2":33.92914,"BASE":34.37874,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.4496,"PCHG2":1.32513,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-14 19:35:51","ADY":193,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-186","SUBJID":"id-186","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.52118,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 19:35:51","TRTEDTM":"2024-02-03 13:35:51","TRT01SDTM":"2021-02-02 19:35:51","TRT01EDTM":"2023-02-03 07:35:51","TRT02SDTM":"2023-02-03 07:35:51","TRT02EDTM":"2024-02-03 13:35:51","AP01SDTM":"2021-02-02 19:35:51","AP01EDTM":"2023-02-03 07:35:51","AP02SDTM":"2023-02-03 07:35:51","AP02EDTM":"2024-02-03 13:35:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-18","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3427,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.92971,"AVALU":"U/L","BASE2":33.92914,"BASE":34.37874,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.99942,"PCHG2":-29.4715,"CHG":-10.44903,"PCHG":-30.39387,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-19 19:35:51","ADY":382,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-186","SUBJID":"id-186","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.52118,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 19:35:51","TRTEDTM":"2024-02-03 13:35:51","TRT01SDTM":"2021-02-02 19:35:51","TRT01EDTM":"2023-02-03 07:35:51","TRT02SDTM":"2023-02-03 07:35:51","TRT02EDTM":"2024-02-03 13:35:51","AP01SDTM":"2021-02-02 19:35:51","AP01EDTM":"2023-02-03 07:35:51","AP02SDTM":"2023-02-03 07:35:51","AP02EDTM":"2024-02-03 13:35:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-18","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3739,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.64286,"AVALU":"U/L","BASE2":33.92914,"BASE":34.37874,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.28628,"PCHG2":-21.47499,"CHG":-7.73588,"PCHG":-22.50193,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-10 19:35:51","ADY":676,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-186","SUBJID":"id-186","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.52118,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 19:35:51","TRTEDTM":"2024-02-03 13:35:51","TRT01SDTM":"2021-02-02 19:35:51","TRT01EDTM":"2023-02-03 07:35:51","TRT02SDTM":"2023-02-03 07:35:51","TRT02EDTM":"2024-02-03 13:35:51","AP01SDTM":"2021-02-02 19:35:51","AP01EDTM":"2023-02-03 07:35:51","AP02SDTM":"2023-02-03 07:35:51","AP02EDTM":"2024-02-03 13:35:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-18","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5189,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.74979,"AVALU":"U/L","BASE2":33.92914,"BASE":34.37874,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.17934,"PCHG2":-21.15982,"CHG":-7.62895,"PCHG":-22.19088,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-19 19:35:51","ADY":836,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-186","SUBJID":"id-186","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.52118,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 19:35:51","TRTEDTM":"2024-02-03 13:35:51","TRT01SDTM":"2021-02-02 19:35:51","TRT01EDTM":"2023-02-03 07:35:51","TRT02SDTM":"2023-02-03 07:35:51","TRT02EDTM":"2024-02-03 13:35:51","AP01SDTM":"2021-02-02 19:35:51","AP01EDTM":"2023-02-03 07:35:51","AP02SDTM":"2023-02-03 07:35:51","AP02EDTM":"2024-02-03 13:35:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-18","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7356,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.55647,"AVALU":"U/L","BASE2":33.92914,"BASE":34.37874,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-28.37267,"PCHG2":-83.62332,"CHG":-28.82228,"PCHG":-83.8375,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2023-06-30 19:35:51","ADY":878,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-186","SUBJID":"id-186","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.52118,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 19:35:51","TRTEDTM":"2024-02-03 13:35:51","TRT01SDTM":"2021-02-02 19:35:51","TRT01EDTM":"2023-02-03 07:35:51","TRT02SDTM":"2023-02-03 07:35:51","TRT02EDTM":"2024-02-03 13:35:51","AP01SDTM":"2021-02-02 19:35:51","AP01EDTM":"2023-02-03 07:35:51","AP02SDTM":"2023-02-03 07:35:51","AP02EDTM":"2024-02-03 13:35:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-18","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":519,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.32741,"AVALU":"U/L","BASE2":33.92914,"BASE":34.37874,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-30.60173,"PCHG2":-90.19306,"CHG":-31.05133,"PCHG":-90.32132,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2023-09-22 19:35:51","ADY":962,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-186","SUBJID":"id-186","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.52118,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 19:35:51","TRTEDTM":"2024-02-03 13:35:51","TRT01SDTM":"2021-02-02 19:35:51","TRT01EDTM":"2023-02-03 07:35:51","TRT02SDTM":"2023-02-03 07:35:51","TRT02EDTM":"2024-02-03 13:35:51","AP01SDTM":"2021-02-02 19:35:51","AP01EDTM":"2023-02-03 07:35:51","AP02SDTM":"2023-02-03 07:35:51","AP02EDTM":"2024-02-03 13:35:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-18","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6977,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.51087,"AVALU":"mg/L","BASE2":8.51087,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-03 19:35:51","ADY":121,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-186","SUBJID":"id-186","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.52118,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 19:35:51","TRTEDTM":"2024-02-03 13:35:51","TRT01SDTM":"2021-02-02 19:35:51","TRT01EDTM":"2023-02-03 07:35:51","TRT02SDTM":"2023-02-03 07:35:51","TRT02EDTM":"2024-02-03 13:35:51","AP01SDTM":"2021-02-02 19:35:51","AP01EDTM":"2023-02-03 07:35:51","AP02SDTM":"2023-02-03 07:35:51","AP02EDTM":"2024-02-03 13:35:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-18","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4830,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.33116,"AVALU":"mg/L","BASE2":8.51087,"BASE":9.33116,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.82028,"PCHG2":9.63806,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-14 19:35:51","ADY":193,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-186","SUBJID":"id-186","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.52118,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 19:35:51","TRTEDTM":"2024-02-03 13:35:51","TRT01SDTM":"2021-02-02 19:35:51","TRT01EDTM":"2023-02-03 07:35:51","TRT02SDTM":"2023-02-03 07:35:51","TRT02EDTM":"2024-02-03 13:35:51","AP01SDTM":"2021-02-02 19:35:51","AP01EDTM":"2023-02-03 07:35:51","AP02SDTM":"2023-02-03 07:35:51","AP02EDTM":"2024-02-03 13:35:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-18","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6317,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.35097,"AVALU":"mg/L","BASE2":8.51087,"BASE":9.33116,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.84009,"PCHG2":9.87084,"CHG":0.01981,"PCHG":0.21231,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-19 19:35:51","ADY":382,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-186","SUBJID":"id-186","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.52118,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 19:35:51","TRTEDTM":"2024-02-03 13:35:51","TRT01SDTM":"2021-02-02 19:35:51","TRT01EDTM":"2023-02-03 07:35:51","TRT02SDTM":"2023-02-03 07:35:51","TRT02EDTM":"2024-02-03 13:35:51","AP01SDTM":"2021-02-02 19:35:51","AP01EDTM":"2023-02-03 07:35:51","AP02SDTM":"2023-02-03 07:35:51","AP02EDTM":"2024-02-03 13:35:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-18","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6289,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.36493,"AVALU":"mg/L","BASE2":8.51087,"BASE":9.33116,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14594,"PCHG2":-1.71476,"CHG":-0.96622,"PCHG":-10.35481,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-10 19:35:51","ADY":676,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-186","SUBJID":"id-186","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.52118,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 19:35:51","TRTEDTM":"2024-02-03 13:35:51","TRT01SDTM":"2021-02-02 19:35:51","TRT01EDTM":"2023-02-03 07:35:51","TRT02SDTM":"2023-02-03 07:35:51","TRT02EDTM":"2024-02-03 13:35:51","AP01SDTM":"2021-02-02 19:35:51","AP01EDTM":"2023-02-03 07:35:51","AP02SDTM":"2023-02-03 07:35:51","AP02EDTM":"2024-02-03 13:35:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-18","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3902,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.23616,"AVALU":"mg/L","BASE2":8.51087,"BASE":9.33116,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.27472,"PCHG2":-3.22785,"CHG":-1.095,"PCHG":-11.7349,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-19 19:35:51","ADY":836,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-186","SUBJID":"id-186","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.52118,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 19:35:51","TRTEDTM":"2024-02-03 13:35:51","TRT01SDTM":"2021-02-02 19:35:51","TRT01EDTM":"2023-02-03 07:35:51","TRT02SDTM":"2023-02-03 07:35:51","TRT02EDTM":"2024-02-03 13:35:51","AP01SDTM":"2021-02-02 19:35:51","AP01EDTM":"2023-02-03 07:35:51","AP02SDTM":"2023-02-03 07:35:51","AP02EDTM":"2024-02-03 13:35:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-18","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5438,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.75406,"AVALU":"mg/L","BASE2":8.51087,"BASE":9.33116,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.24318,"PCHG2":14.607,"CHG":0.4229,"PCHG":4.53213,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-30 19:35:51","ADY":878,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-186","SUBJID":"id-186","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.52118,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 19:35:51","TRTEDTM":"2024-02-03 13:35:51","TRT01SDTM":"2021-02-02 19:35:51","TRT01EDTM":"2023-02-03 07:35:51","TRT02SDTM":"2023-02-03 07:35:51","TRT02EDTM":"2024-02-03 13:35:51","AP01SDTM":"2021-02-02 19:35:51","AP01EDTM":"2023-02-03 07:35:51","AP02SDTM":"2023-02-03 07:35:51","AP02EDTM":"2024-02-03 13:35:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-18","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6498,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.16724,"AVALU":"mg/L","BASE2":8.51087,"BASE":9.33116,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.65637,"PCHG2":19.46179,"CHG":0.83609,"PCHG":8.96015,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2023-09-22 19:35:51","ADY":962,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-186","SUBJID":"id-186","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.52118,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 19:35:51","TRTEDTM":"2024-02-03 13:35:51","TRT01SDTM":"2021-02-02 19:35:51","TRT01EDTM":"2023-02-03 07:35:51","TRT02SDTM":"2023-02-03 07:35:51","TRT02EDTM":"2024-02-03 13:35:51","AP01SDTM":"2021-02-02 19:35:51","AP01EDTM":"2023-02-03 07:35:51","AP02SDTM":"2023-02-03 07:35:51","AP02EDTM":"2024-02-03 13:35:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-18","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7897,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85676,"AVALU":"g/L","BASE2":2.85676,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-03 19:35:51","ADY":121,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-186","SUBJID":"id-186","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.52118,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 19:35:51","TRTEDTM":"2024-02-03 13:35:51","TRT01SDTM":"2021-02-02 19:35:51","TRT01EDTM":"2023-02-03 07:35:51","TRT02SDTM":"2023-02-03 07:35:51","TRT02EDTM":"2024-02-03 13:35:51","AP01SDTM":"2021-02-02 19:35:51","AP01EDTM":"2023-02-03 07:35:51","AP02SDTM":"2023-02-03 07:35:51","AP02EDTM":"2024-02-03 13:35:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-18","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3582,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9147,"AVALU":"g/L","BASE2":2.85676,"BASE":2.9147,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.05794,"PCHG2":2.02806,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-14 19:35:51","ADY":193,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-186","SUBJID":"id-186","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.52118,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 19:35:51","TRTEDTM":"2024-02-03 13:35:51","TRT01SDTM":"2021-02-02 19:35:51","TRT01EDTM":"2023-02-03 07:35:51","TRT02SDTM":"2023-02-03 07:35:51","TRT02EDTM":"2024-02-03 13:35:51","AP01SDTM":"2021-02-02 19:35:51","AP01EDTM":"2023-02-03 07:35:51","AP02SDTM":"2023-02-03 07:35:51","AP02EDTM":"2024-02-03 13:35:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-18","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7596,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84918,"AVALU":"g/L","BASE2":2.85676,"BASE":2.9147,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00758,"PCHG2":-0.26529,"CHG":-0.06552,"PCHG":-2.24777,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-19 19:35:51","ADY":382,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-186","SUBJID":"id-186","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.52118,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 19:35:51","TRTEDTM":"2024-02-03 13:35:51","TRT01SDTM":"2021-02-02 19:35:51","TRT01EDTM":"2023-02-03 07:35:51","TRT02SDTM":"2023-02-03 07:35:51","TRT02EDTM":"2024-02-03 13:35:51","AP01SDTM":"2021-02-02 19:35:51","AP01EDTM":"2023-02-03 07:35:51","AP02SDTM":"2023-02-03 07:35:51","AP02EDTM":"2024-02-03 13:35:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-18","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":966,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86855,"AVALU":"g/L","BASE2":2.85676,"BASE":2.9147,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01179,"PCHG2":0.41274,"CHG":-0.04615,"PCHG":-1.58321,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-10 19:35:51","ADY":676,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-186","SUBJID":"id-186","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.52118,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 19:35:51","TRTEDTM":"2024-02-03 13:35:51","TRT01SDTM":"2021-02-02 19:35:51","TRT01EDTM":"2023-02-03 07:35:51","TRT02SDTM":"2023-02-03 07:35:51","TRT02EDTM":"2024-02-03 13:35:51","AP01SDTM":"2021-02-02 19:35:51","AP01EDTM":"2023-02-03 07:35:51","AP02SDTM":"2023-02-03 07:35:51","AP02EDTM":"2024-02-03 13:35:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-18","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6992,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86241,"AVALU":"g/L","BASE2":2.85676,"BASE":2.9147,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00565,"PCHG2":0.19775,"CHG":-0.05229,"PCHG":-1.79393,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-19 19:35:51","ADY":836,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-186","SUBJID":"id-186","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.52118,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 19:35:51","TRTEDTM":"2024-02-03 13:35:51","TRT01SDTM":"2021-02-02 19:35:51","TRT01EDTM":"2023-02-03 07:35:51","TRT02SDTM":"2023-02-03 07:35:51","TRT02EDTM":"2024-02-03 13:35:51","AP01SDTM":"2021-02-02 19:35:51","AP01EDTM":"2023-02-03 07:35:51","AP02SDTM":"2023-02-03 07:35:51","AP02EDTM":"2024-02-03 13:35:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-18","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1653,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84593,"AVALU":"g/L","BASE2":2.85676,"BASE":2.9147,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01083,"PCHG2":-0.37899,"CHG":-0.06876,"PCHG":-2.35921,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-30 19:35:51","ADY":878,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-186","SUBJID":"id-186","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.52118,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 19:35:51","TRTEDTM":"2024-02-03 13:35:51","TRT01SDTM":"2021-02-02 19:35:51","TRT01EDTM":"2023-02-03 07:35:51","TRT02SDTM":"2023-02-03 07:35:51","TRT02EDTM":"2024-02-03 13:35:51","AP01SDTM":"2021-02-02 19:35:51","AP01EDTM":"2023-02-03 07:35:51","AP02SDTM":"2023-02-03 07:35:51","AP02EDTM":"2024-02-03 13:35:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-18","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4646,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86903,"AVALU":"g/L","BASE2":2.85676,"BASE":2.9147,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01227,"PCHG2":0.42948,"CHG":-0.04567,"PCHG":-1.5668,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-22 19:35:51","ADY":962,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-197","SUBJID":"id-197","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.65225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-29","TRTSDTM":"2020-06-01 07:02:57","TRTEDTM":"2022-02-12 08:33:57","TRT01SDTM":"2020-06-01 07:02:57","TRT01EDTM":"2021-02-12 02:33:57","TRT02SDTM":"2021-02-12 02:33:57","TRT02EDTM":"2022-02-12 08:33:57","AP01SDTM":"2020-06-01 07:02:57","AP01EDTM":"2021-02-12 02:33:57","AP02SDTM":"2021-02-12 02:33:57","AP02EDTM":"2022-02-12 08:33:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":622,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7183,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.15669,"AVALU":"U/L","BASE2":15.15669,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-08 07:02:57","ADY":7,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-197","SUBJID":"id-197","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.65225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-29","TRTSDTM":"2020-06-01 07:02:57","TRTEDTM":"2022-02-12 08:33:57","TRT01SDTM":"2020-06-01 07:02:57","TRT01EDTM":"2021-02-12 02:33:57","TRT02SDTM":"2021-02-12 02:33:57","TRT02EDTM":"2022-02-12 08:33:57","AP01SDTM":"2020-06-01 07:02:57","AP01EDTM":"2021-02-12 02:33:57","AP02SDTM":"2021-02-12 02:33:57","AP02EDTM":"2022-02-12 08:33:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":622,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1361,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.03359,"AVALU":"U/L","BASE2":15.15669,"BASE":23.03359,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":7.87689,"PCHG2":51.96973,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-01 07:02:57","ADY":92,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-197","SUBJID":"id-197","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.65225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-29","TRTSDTM":"2020-06-01 07:02:57","TRTEDTM":"2022-02-12 08:33:57","TRT01SDTM":"2020-06-01 07:02:57","TRT01EDTM":"2021-02-12 02:33:57","TRT02SDTM":"2021-02-12 02:33:57","TRT02EDTM":"2022-02-12 08:33:57","AP01SDTM":"2020-06-01 07:02:57","AP01EDTM":"2021-02-12 02:33:57","AP02SDTM":"2021-02-12 02:33:57","AP02EDTM":"2022-02-12 08:33:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":622,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4710,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.88816,"AVALU":"U/L","BASE2":15.15669,"BASE":23.03359,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.26853,"PCHG2":-14.96718,"CHG":-10.14542,"PCHG":-44.04621,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-11 07:02:57","ADY":193,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-197","SUBJID":"id-197","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.65225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-29","TRTSDTM":"2020-06-01 07:02:57","TRTEDTM":"2022-02-12 08:33:57","TRT01SDTM":"2020-06-01 07:02:57","TRT01EDTM":"2021-02-12 02:33:57","TRT02SDTM":"2021-02-12 02:33:57","TRT02EDTM":"2022-02-12 08:33:57","AP01SDTM":"2020-06-01 07:02:57","AP01EDTM":"2021-02-12 02:33:57","AP02SDTM":"2021-02-12 02:33:57","AP02EDTM":"2022-02-12 08:33:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":622,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":101,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.68735,"AVALU":"U/L","BASE2":15.15669,"BASE":23.03359,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.46935,"PCHG2":-49.28084,"CHG":-15.34624,"PCHG":-66.62548,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-28 07:02:57","ADY":210,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-197","SUBJID":"id-197","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.65225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-29","TRTSDTM":"2020-06-01 07:02:57","TRTEDTM":"2022-02-12 08:33:57","TRT01SDTM":"2020-06-01 07:02:57","TRT01EDTM":"2021-02-12 02:33:57","TRT02SDTM":"2021-02-12 02:33:57","TRT02EDTM":"2022-02-12 08:33:57","AP01SDTM":"2020-06-01 07:02:57","AP01EDTM":"2021-02-12 02:33:57","AP02SDTM":"2021-02-12 02:33:57","AP02EDTM":"2022-02-12 08:33:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":622,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3025,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.22201,"AVALU":"U/L","BASE2":15.15669,"BASE":23.03359,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06532,"PCHG2":0.43095,"CHG":-7.81157,"PCHG":-33.91384,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-05 07:02:57","ADY":277,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-197","SUBJID":"id-197","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.65225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-29","TRTSDTM":"2020-06-01 07:02:57","TRTEDTM":"2022-02-12 08:33:57","TRT01SDTM":"2020-06-01 07:02:57","TRT01EDTM":"2021-02-12 02:33:57","TRT02SDTM":"2021-02-12 02:33:57","TRT02EDTM":"2022-02-12 08:33:57","AP01SDTM":"2020-06-01 07:02:57","AP01EDTM":"2021-02-12 02:33:57","AP02SDTM":"2021-02-12 02:33:57","AP02EDTM":"2022-02-12 08:33:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":622,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6539,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.48713,"AVALU":"U/L","BASE2":15.15669,"BASE":23.03359,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.66957,"PCHG2":-17.61312,"CHG":-10.54646,"PCHG":-45.78731,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-06 07:02:57","ADY":523,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-197","SUBJID":"id-197","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.65225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-29","TRTSDTM":"2020-06-01 07:02:57","TRTEDTM":"2022-02-12 08:33:57","TRT01SDTM":"2020-06-01 07:02:57","TRT01EDTM":"2021-02-12 02:33:57","TRT02SDTM":"2021-02-12 02:33:57","TRT02EDTM":"2022-02-12 08:33:57","AP01SDTM":"2020-06-01 07:02:57","AP01EDTM":"2021-02-12 02:33:57","AP02SDTM":"2021-02-12 02:33:57","AP02EDTM":"2022-02-12 08:33:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":622,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4992,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.88939,"AVALU":"U/L","BASE2":15.15669,"BASE":23.03359,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.7327,"PCHG2":31.22514,"CHG":-3.14419,"PCHG":-13.65047,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-05 07:02:57","ADY":552,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-197","SUBJID":"id-197","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.65225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-29","TRTSDTM":"2020-06-01 07:02:57","TRTEDTM":"2022-02-12 08:33:57","TRT01SDTM":"2020-06-01 07:02:57","TRT01EDTM":"2021-02-12 02:33:57","TRT02SDTM":"2021-02-12 02:33:57","TRT02EDTM":"2022-02-12 08:33:57","AP01SDTM":"2020-06-01 07:02:57","AP01EDTM":"2021-02-12 02:33:57","AP02SDTM":"2021-02-12 02:33:57","AP02EDTM":"2022-02-12 08:33:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":622,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7793,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.54312,"AVALU":"mg/L","BASE2":8.54312,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-08 07:02:57","ADY":7,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-197","SUBJID":"id-197","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.65225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-29","TRTSDTM":"2020-06-01 07:02:57","TRTEDTM":"2022-02-12 08:33:57","TRT01SDTM":"2020-06-01 07:02:57","TRT01EDTM":"2021-02-12 02:33:57","TRT02SDTM":"2021-02-12 02:33:57","TRT02EDTM":"2022-02-12 08:33:57","AP01SDTM":"2020-06-01 07:02:57","AP01EDTM":"2021-02-12 02:33:57","AP02SDTM":"2021-02-12 02:33:57","AP02EDTM":"2022-02-12 08:33:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":622,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3729,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.31055,"AVALU":"mg/L","BASE2":8.54312,"BASE":9.31055,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.76743,"PCHG2":8.98297,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-01 07:02:57","ADY":92,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-197","SUBJID":"id-197","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.65225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-29","TRTSDTM":"2020-06-01 07:02:57","TRTEDTM":"2022-02-12 08:33:57","TRT01SDTM":"2020-06-01 07:02:57","TRT01EDTM":"2021-02-12 02:33:57","TRT02SDTM":"2021-02-12 02:33:57","TRT02EDTM":"2022-02-12 08:33:57","AP01SDTM":"2020-06-01 07:02:57","AP01EDTM":"2021-02-12 02:33:57","AP02SDTM":"2021-02-12 02:33:57","AP02EDTM":"2022-02-12 08:33:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":622,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5340,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.26366,"AVALU":"mg/L","BASE2":8.54312,"BASE":9.31055,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.72054,"PCHG2":8.43418,"CHG":-0.04688,"PCHG":-0.50355,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-11 07:02:57","ADY":193,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-197","SUBJID":"id-197","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.65225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-29","TRTSDTM":"2020-06-01 07:02:57","TRTEDTM":"2022-02-12 08:33:57","TRT01SDTM":"2020-06-01 07:02:57","TRT01EDTM":"2021-02-12 02:33:57","TRT02SDTM":"2021-02-12 02:33:57","TRT02EDTM":"2022-02-12 08:33:57","AP01SDTM":"2020-06-01 07:02:57","AP01EDTM":"2021-02-12 02:33:57","AP02SDTM":"2021-02-12 02:33:57","AP02EDTM":"2022-02-12 08:33:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":622,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4489,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.30466,"AVALU":"mg/L","BASE2":8.54312,"BASE":9.31055,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.76154,"PCHG2":8.9141,"CHG":-0.00588,"PCHG":-0.0632,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-28 07:02:57","ADY":210,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-197","SUBJID":"id-197","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.65225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-29","TRTSDTM":"2020-06-01 07:02:57","TRTEDTM":"2022-02-12 08:33:57","TRT01SDTM":"2020-06-01 07:02:57","TRT01EDTM":"2021-02-12 02:33:57","TRT02SDTM":"2021-02-12 02:33:57","TRT02EDTM":"2022-02-12 08:33:57","AP01SDTM":"2020-06-01 07:02:57","AP01EDTM":"2021-02-12 02:33:57","AP02SDTM":"2021-02-12 02:33:57","AP02EDTM":"2022-02-12 08:33:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":622,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2661,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.75677,"AVALU":"mg/L","BASE2":8.54312,"BASE":9.31055,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.78636,"PCHG2":-9.20455,"CHG":-1.55378,"PCHG":-16.68841,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-03-05 07:02:57","ADY":277,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-197","SUBJID":"id-197","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.65225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-29","TRTSDTM":"2020-06-01 07:02:57","TRTEDTM":"2022-02-12 08:33:57","TRT01SDTM":"2020-06-01 07:02:57","TRT01EDTM":"2021-02-12 02:33:57","TRT02SDTM":"2021-02-12 02:33:57","TRT02EDTM":"2022-02-12 08:33:57","AP01SDTM":"2020-06-01 07:02:57","AP01EDTM":"2021-02-12 02:33:57","AP02SDTM":"2021-02-12 02:33:57","AP02EDTM":"2022-02-12 08:33:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":622,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6611,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.94603,"AVALU":"mg/L","BASE2":8.54312,"BASE":9.31055,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.40291,"PCHG2":16.42151,"CHG":0.63548,"PCHG":6.82541,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-06 07:02:57","ADY":523,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-197","SUBJID":"id-197","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.65225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-29","TRTSDTM":"2020-06-01 07:02:57","TRTEDTM":"2022-02-12 08:33:57","TRT01SDTM":"2020-06-01 07:02:57","TRT01EDTM":"2021-02-12 02:33:57","TRT02SDTM":"2021-02-12 02:33:57","TRT02EDTM":"2022-02-12 08:33:57","AP01SDTM":"2020-06-01 07:02:57","AP01EDTM":"2021-02-12 02:33:57","AP02SDTM":"2021-02-12 02:33:57","AP02EDTM":"2022-02-12 08:33:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":622,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7882,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.60715,"AVALU":"mg/L","BASE2":8.54312,"BASE":9.31055,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.93598,"PCHG2":-10.95589,"CHG":-1.7034,"PCHG":-18.29539,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-12-05 07:02:57","ADY":552,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-197","SUBJID":"id-197","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.65225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-29","TRTSDTM":"2020-06-01 07:02:57","TRTEDTM":"2022-02-12 08:33:57","TRT01SDTM":"2020-06-01 07:02:57","TRT01EDTM":"2021-02-12 02:33:57","TRT02SDTM":"2021-02-12 02:33:57","TRT02EDTM":"2022-02-12 08:33:57","AP01SDTM":"2020-06-01 07:02:57","AP01EDTM":"2021-02-12 02:33:57","AP02SDTM":"2021-02-12 02:33:57","AP02EDTM":"2022-02-12 08:33:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":622,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":407,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00253,"AVALU":"g/L","BASE2":3.00253,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-06-08 07:02:57","ADY":7,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-197","SUBJID":"id-197","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.65225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-29","TRTSDTM":"2020-06-01 07:02:57","TRTEDTM":"2022-02-12 08:33:57","TRT01SDTM":"2020-06-01 07:02:57","TRT01EDTM":"2021-02-12 02:33:57","TRT02SDTM":"2021-02-12 02:33:57","TRT02EDTM":"2022-02-12 08:33:57","AP01SDTM":"2020-06-01 07:02:57","AP01EDTM":"2021-02-12 02:33:57","AP02SDTM":"2021-02-12 02:33:57","AP02EDTM":"2022-02-12 08:33:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":622,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":571,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8787,"AVALU":"g/L","BASE2":3.00253,"BASE":2.8787,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.12383,"PCHG2":-4.12405,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-01 07:02:57","ADY":92,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-197","SUBJID":"id-197","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.65225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-29","TRTSDTM":"2020-06-01 07:02:57","TRTEDTM":"2022-02-12 08:33:57","TRT01SDTM":"2020-06-01 07:02:57","TRT01EDTM":"2021-02-12 02:33:57","TRT02SDTM":"2021-02-12 02:33:57","TRT02EDTM":"2022-02-12 08:33:57","AP01SDTM":"2020-06-01 07:02:57","AP01EDTM":"2021-02-12 02:33:57","AP02SDTM":"2021-02-12 02:33:57","AP02EDTM":"2022-02-12 08:33:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":622,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3047,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01206,"AVALU":"g/L","BASE2":3.00253,"BASE":2.8787,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00953,"PCHG2":0.31753,"CHG":0.13336,"PCHG":4.63264,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-12-11 07:02:57","ADY":193,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-197","SUBJID":"id-197","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.65225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-29","TRTSDTM":"2020-06-01 07:02:57","TRTEDTM":"2022-02-12 08:33:57","TRT01SDTM":"2020-06-01 07:02:57","TRT01EDTM":"2021-02-12 02:33:57","TRT02SDTM":"2021-02-12 02:33:57","TRT02EDTM":"2022-02-12 08:33:57","AP01SDTM":"2020-06-01 07:02:57","AP01EDTM":"2021-02-12 02:33:57","AP02SDTM":"2021-02-12 02:33:57","AP02EDTM":"2022-02-12 08:33:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":622,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6432,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8617,"AVALU":"g/L","BASE2":3.00253,"BASE":2.8787,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14083,"PCHG2":-4.6904,"CHG":-0.017,"PCHG":-0.59071,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-28 07:02:57","ADY":210,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-197","SUBJID":"id-197","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.65225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-29","TRTSDTM":"2020-06-01 07:02:57","TRTEDTM":"2022-02-12 08:33:57","TRT01SDTM":"2020-06-01 07:02:57","TRT01EDTM":"2021-02-12 02:33:57","TRT02SDTM":"2021-02-12 02:33:57","TRT02EDTM":"2022-02-12 08:33:57","AP01SDTM":"2020-06-01 07:02:57","AP01EDTM":"2021-02-12 02:33:57","AP02SDTM":"2021-02-12 02:33:57","AP02EDTM":"2022-02-12 08:33:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":622,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2843,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85055,"AVALU":"g/L","BASE2":3.00253,"BASE":2.8787,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15198,"PCHG2":-5.06162,"CHG":-0.02815,"PCHG":-0.97789,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-05 07:02:57","ADY":277,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-197","SUBJID":"id-197","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.65225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-29","TRTSDTM":"2020-06-01 07:02:57","TRTEDTM":"2022-02-12 08:33:57","TRT01SDTM":"2020-06-01 07:02:57","TRT01EDTM":"2021-02-12 02:33:57","TRT02SDTM":"2021-02-12 02:33:57","TRT02EDTM":"2022-02-12 08:33:57","AP01SDTM":"2020-06-01 07:02:57","AP01EDTM":"2021-02-12 02:33:57","AP02SDTM":"2021-02-12 02:33:57","AP02EDTM":"2022-02-12 08:33:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":622,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8036,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93631,"AVALU":"g/L","BASE2":3.00253,"BASE":2.8787,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06622,"PCHG2":-2.20553,"CHG":0.0576,"PCHG":2.00104,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-06 07:02:57","ADY":523,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-197","SUBJID":"id-197","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.65225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-29","TRTSDTM":"2020-06-01 07:02:57","TRTEDTM":"2022-02-12 08:33:57","TRT01SDTM":"2020-06-01 07:02:57","TRT01EDTM":"2021-02-12 02:33:57","TRT02SDTM":"2021-02-12 02:33:57","TRT02EDTM":"2022-02-12 08:33:57","AP01SDTM":"2020-06-01 07:02:57","AP01EDTM":"2021-02-12 02:33:57","AP02SDTM":"2021-02-12 02:33:57","AP02EDTM":"2022-02-12 08:33:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":622,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4056,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78879,"AVALU":"g/L","BASE2":3.00253,"BASE":2.8787,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21373,"PCHG2":-7.11848,"CHG":-0.08991,"PCHG":-3.12324,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-05 07:02:57","ADY":552,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-199","SUBJID":"id-199","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.85826,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 21:47:26","TRTEDTM":"2022-02-19 21:37:55","TRT01SDTM":"2020-01-08 21:47:26","TRT01EDTM":"2021-02-19 15:37:55","TRT02SDTM":"2021-02-19 15:37:55","TRT02EDTM":"2022-02-19 21:37:55","AP01SDTM":"2020-01-08 21:47:26","AP01EDTM":"2021-02-19 15:37:55","AP02SDTM":"2021-02-19 15:37:55","AP02EDTM":"2022-02-19 21:37:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":773,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":779,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3331,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.22847,"AVALU":"U/L","BASE2":17.22847,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-23 21:47:26","ADY":75,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-199","SUBJID":"id-199","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.85826,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 21:47:26","TRTEDTM":"2022-02-19 21:37:55","TRT01SDTM":"2020-01-08 21:47:26","TRT01EDTM":"2021-02-19 15:37:55","TRT02SDTM":"2021-02-19 15:37:55","TRT02EDTM":"2022-02-19 21:37:55","AP01SDTM":"2020-01-08 21:47:26","AP01EDTM":"2021-02-19 15:37:55","AP02SDTM":"2021-02-19 15:37:55","AP02EDTM":"2022-02-19 21:37:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":773,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":779,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4870,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.20091,"AVALU":"U/L","BASE2":17.22847,"BASE":25.20091,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":7.97244,"PCHG2":46.2748,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-08 21:47:26","ADY":182,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-199","SUBJID":"id-199","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.85826,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 21:47:26","TRTEDTM":"2022-02-19 21:37:55","TRT01SDTM":"2020-01-08 21:47:26","TRT01EDTM":"2021-02-19 15:37:55","TRT02SDTM":"2021-02-19 15:37:55","TRT02EDTM":"2022-02-19 21:37:55","AP01SDTM":"2020-01-08 21:47:26","AP01EDTM":"2021-02-19 15:37:55","AP02SDTM":"2021-02-19 15:37:55","AP02EDTM":"2022-02-19 21:37:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":773,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":779,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2192,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.06688,"AVALU":"U/L","BASE2":17.22847,"BASE":25.20091,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.16159,"PCHG2":-6.74227,"CHG":-9.13403,"PCHG":-36.24484,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-24 21:47:26","ADY":198,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-199","SUBJID":"id-199","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.85826,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 21:47:26","TRTEDTM":"2022-02-19 21:37:55","TRT01SDTM":"2020-01-08 21:47:26","TRT01EDTM":"2021-02-19 15:37:55","TRT02SDTM":"2021-02-19 15:37:55","TRT02EDTM":"2022-02-19 21:37:55","AP01SDTM":"2020-01-08 21:47:26","AP01EDTM":"2021-02-19 15:37:55","AP02SDTM":"2021-02-19 15:37:55","AP02EDTM":"2022-02-19 21:37:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":773,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":779,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2893,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.99364,"AVALU":"U/L","BASE2":17.22847,"BASE":25.20091,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.76517,"PCHG2":62.48478,"CHG":2.79273,"PCHG":11.08186,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-29 21:47:26","ADY":265,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-199","SUBJID":"id-199","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.85826,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 21:47:26","TRTEDTM":"2022-02-19 21:37:55","TRT01SDTM":"2020-01-08 21:47:26","TRT01EDTM":"2021-02-19 15:37:55","TRT02SDTM":"2021-02-19 15:37:55","TRT02EDTM":"2022-02-19 21:37:55","AP01SDTM":"2020-01-08 21:47:26","AP01EDTM":"2021-02-19 15:37:55","AP02SDTM":"2021-02-19 15:37:55","AP02EDTM":"2022-02-19 21:37:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":773,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":779,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1717,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.3041,"AVALU":"U/L","BASE2":17.22847,"BASE":25.20091,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.92437,"PCHG2":-69.21317,"CHG":-19.89681,"PCHG":-78.95274,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-10-11 21:47:26","ADY":277,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-199","SUBJID":"id-199","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.85826,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 21:47:26","TRTEDTM":"2022-02-19 21:37:55","TRT01SDTM":"2020-01-08 21:47:26","TRT01EDTM":"2021-02-19 15:37:55","TRT02SDTM":"2021-02-19 15:37:55","TRT02EDTM":"2022-02-19 21:37:55","AP01SDTM":"2020-01-08 21:47:26","AP01EDTM":"2021-02-19 15:37:55","AP02SDTM":"2021-02-19 15:37:55","AP02EDTM":"2022-02-19 21:37:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":773,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":779,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3215,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.32938,"AVALU":"U/L","BASE2":17.22847,"BASE":25.20091,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10091,"PCHG2":0.58571,"CHG":-7.87153,"PCHG":-31.23511,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-01 21:47:26","ADY":602,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-199","SUBJID":"id-199","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.85826,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 21:47:26","TRTEDTM":"2022-02-19 21:37:55","TRT01SDTM":"2020-01-08 21:47:26","TRT01EDTM":"2021-02-19 15:37:55","TRT02SDTM":"2021-02-19 15:37:55","TRT02EDTM":"2022-02-19 21:37:55","AP01SDTM":"2020-01-08 21:47:26","AP01EDTM":"2021-02-19 15:37:55","AP02SDTM":"2021-02-19 15:37:55","AP02EDTM":"2022-02-19 21:37:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":773,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":779,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6307,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.81687,"AVALU":"U/L","BASE2":17.22847,"BASE":25.20091,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.4116,"PCHG2":-60.43254,"CHG":-18.38404,"PCHG":-72.94991,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-11-10 21:47:26","ADY":672,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-199","SUBJID":"id-199","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.85826,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 21:47:26","TRTEDTM":"2022-02-19 21:37:55","TRT01SDTM":"2020-01-08 21:47:26","TRT01EDTM":"2021-02-19 15:37:55","TRT02SDTM":"2021-02-19 15:37:55","TRT02EDTM":"2022-02-19 21:37:55","AP01SDTM":"2020-01-08 21:47:26","AP01EDTM":"2021-02-19 15:37:55","AP02SDTM":"2021-02-19 15:37:55","AP02EDTM":"2022-02-19 21:37:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":773,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":779,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":543,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.30595,"AVALU":"mg/L","BASE2":9.30595,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-23 21:47:26","ADY":75,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-199","SUBJID":"id-199","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.85826,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 21:47:26","TRTEDTM":"2022-02-19 21:37:55","TRT01SDTM":"2020-01-08 21:47:26","TRT01EDTM":"2021-02-19 15:37:55","TRT02SDTM":"2021-02-19 15:37:55","TRT02EDTM":"2022-02-19 21:37:55","AP01SDTM":"2020-01-08 21:47:26","AP01EDTM":"2021-02-19 15:37:55","AP02SDTM":"2021-02-19 15:37:55","AP02EDTM":"2022-02-19 21:37:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":773,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":779,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5296,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.58013,"AVALU":"mg/L","BASE2":9.30595,"BASE":8.58013,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.72583,"PCHG2":-7.79959,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-08 21:47:26","ADY":182,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-199","SUBJID":"id-199","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.85826,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 21:47:26","TRTEDTM":"2022-02-19 21:37:55","TRT01SDTM":"2020-01-08 21:47:26","TRT01EDTM":"2021-02-19 15:37:55","TRT02SDTM":"2021-02-19 15:37:55","TRT02EDTM":"2022-02-19 21:37:55","AP01SDTM":"2020-01-08 21:47:26","AP01EDTM":"2021-02-19 15:37:55","AP02SDTM":"2021-02-19 15:37:55","AP02EDTM":"2022-02-19 21:37:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":773,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":779,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5841,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.02932,"AVALU":"mg/L","BASE2":9.30595,"BASE":8.58013,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.27663,"PCHG2":-13.71847,"CHG":-0.55081,"PCHG":-6.41959,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-24 21:47:26","ADY":198,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-199","SUBJID":"id-199","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.85826,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 21:47:26","TRTEDTM":"2022-02-19 21:37:55","TRT01SDTM":"2020-01-08 21:47:26","TRT01EDTM":"2021-02-19 15:37:55","TRT02SDTM":"2021-02-19 15:37:55","TRT02EDTM":"2022-02-19 21:37:55","AP01SDTM":"2020-01-08 21:47:26","AP01EDTM":"2021-02-19 15:37:55","AP02SDTM":"2021-02-19 15:37:55","AP02EDTM":"2022-02-19 21:37:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":773,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":779,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7579,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.75458,"AVALU":"mg/L","BASE2":9.30595,"BASE":8.58013,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.55137,"PCHG2":-16.67075,"CHG":-0.82555,"PCHG":-9.62161,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-09-29 21:47:26","ADY":265,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-199","SUBJID":"id-199","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.85826,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 21:47:26","TRTEDTM":"2022-02-19 21:37:55","TRT01SDTM":"2020-01-08 21:47:26","TRT01EDTM":"2021-02-19 15:37:55","TRT02SDTM":"2021-02-19 15:37:55","TRT02EDTM":"2022-02-19 21:37:55","AP01SDTM":"2020-01-08 21:47:26","AP01EDTM":"2021-02-19 15:37:55","AP02SDTM":"2021-02-19 15:37:55","AP02EDTM":"2022-02-19 21:37:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":773,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":779,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6089,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.85564,"AVALU":"mg/L","BASE2":9.30595,"BASE":8.58013,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.45031,"PCHG2":-4.83896,"CHG":0.27551,"PCHG":3.21108,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-11 21:47:26","ADY":277,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-199","SUBJID":"id-199","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.85826,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 21:47:26","TRTEDTM":"2022-02-19 21:37:55","TRT01SDTM":"2020-01-08 21:47:26","TRT01EDTM":"2021-02-19 15:37:55","TRT02SDTM":"2021-02-19 15:37:55","TRT02EDTM":"2022-02-19 21:37:55","AP01SDTM":"2020-01-08 21:47:26","AP01EDTM":"2021-02-19 15:37:55","AP02SDTM":"2021-02-19 15:37:55","AP02EDTM":"2022-02-19 21:37:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":773,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":779,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2149,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.57076,"AVALU":"mg/L","BASE2":9.30595,"BASE":8.58013,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.73519,"PCHG2":-7.90025,"CHG":-0.00937,"PCHG":-0.10918,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-01 21:47:26","ADY":602,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-199","SUBJID":"id-199","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.85826,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 21:47:26","TRTEDTM":"2022-02-19 21:37:55","TRT01SDTM":"2020-01-08 21:47:26","TRT01EDTM":"2021-02-19 15:37:55","TRT02SDTM":"2021-02-19 15:37:55","TRT02EDTM":"2022-02-19 21:37:55","AP01SDTM":"2020-01-08 21:47:26","AP01EDTM":"2021-02-19 15:37:55","AP02SDTM":"2021-02-19 15:37:55","AP02EDTM":"2022-02-19 21:37:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":773,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":779,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1447,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.14776,"AVALU":"mg/L","BASE2":9.30595,"BASE":8.58013,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1582,"PCHG2":-1.69994,"CHG":0.56763,"PCHG":6.61564,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-10 21:47:26","ADY":672,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-199","SUBJID":"id-199","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.85826,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 21:47:26","TRTEDTM":"2022-02-19 21:37:55","TRT01SDTM":"2020-01-08 21:47:26","TRT01EDTM":"2021-02-19 15:37:55","TRT02SDTM":"2021-02-19 15:37:55","TRT02EDTM":"2022-02-19 21:37:55","AP01SDTM":"2020-01-08 21:47:26","AP01EDTM":"2021-02-19 15:37:55","AP02SDTM":"2021-02-19 15:37:55","AP02EDTM":"2022-02-19 21:37:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":773,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":779,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1844,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.10943,"AVALU":"g/L","BASE2":3.10943,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"2","ADTM":"2020-03-23 21:47:26","ADY":75,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-199","SUBJID":"id-199","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.85826,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 21:47:26","TRTEDTM":"2022-02-19 21:37:55","TRT01SDTM":"2020-01-08 21:47:26","TRT01EDTM":"2021-02-19 15:37:55","TRT02SDTM":"2021-02-19 15:37:55","TRT02EDTM":"2022-02-19 21:37:55","AP01SDTM":"2020-01-08 21:47:26","AP01EDTM":"2021-02-19 15:37:55","AP02SDTM":"2021-02-19 15:37:55","AP02EDTM":"2022-02-19 21:37:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":773,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":779,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2971,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.06962,"AVALU":"g/L","BASE2":3.10943,"BASE":3.06962,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.03981,"PCHG2":-1.28019,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2020-07-08 21:47:26","ADY":182,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-199","SUBJID":"id-199","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.85826,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 21:47:26","TRTEDTM":"2022-02-19 21:37:55","TRT01SDTM":"2020-01-08 21:47:26","TRT01EDTM":"2021-02-19 15:37:55","TRT02SDTM":"2021-02-19 15:37:55","TRT02EDTM":"2022-02-19 21:37:55","AP01SDTM":"2020-01-08 21:47:26","AP01EDTM":"2021-02-19 15:37:55","AP02SDTM":"2021-02-19 15:37:55","AP02EDTM":"2022-02-19 21:37:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":773,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":779,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6621,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00248,"AVALU":"g/L","BASE2":3.10943,"BASE":3.06962,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10695,"PCHG2":-3.43953,"CHG":-0.06714,"PCHG":-2.18734,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"3","BTOXGR":"2","ADTM":"2020-07-24 21:47:26","ADY":198,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-199","SUBJID":"id-199","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.85826,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 21:47:26","TRTEDTM":"2022-02-19 21:37:55","TRT01SDTM":"2020-01-08 21:47:26","TRT01EDTM":"2021-02-19 15:37:55","TRT02SDTM":"2021-02-19 15:37:55","TRT02EDTM":"2022-02-19 21:37:55","AP01SDTM":"2020-01-08 21:47:26","AP01EDTM":"2021-02-19 15:37:55","AP02SDTM":"2021-02-19 15:37:55","AP02EDTM":"2022-02-19 21:37:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":773,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":779,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1513,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95249,"AVALU":"g/L","BASE2":3.10943,"BASE":3.06962,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15694,"PCHG2":-5.04713,"CHG":-0.11713,"PCHG":-3.81579,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2020-09-29 21:47:26","ADY":265,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-199","SUBJID":"id-199","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.85826,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 21:47:26","TRTEDTM":"2022-02-19 21:37:55","TRT01SDTM":"2020-01-08 21:47:26","TRT01EDTM":"2021-02-19 15:37:55","TRT02SDTM":"2021-02-19 15:37:55","TRT02EDTM":"2022-02-19 21:37:55","AP01SDTM":"2020-01-08 21:47:26","AP01EDTM":"2021-02-19 15:37:55","AP02SDTM":"2021-02-19 15:37:55","AP02EDTM":"2022-02-19 21:37:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":773,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":779,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1342,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85711,"AVALU":"g/L","BASE2":3.10943,"BASE":3.06962,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.25232,"PCHG2":-8.11454,"CHG":-0.21251,"PCHG":-6.92298,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2020-10-11 21:47:26","ADY":277,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-199","SUBJID":"id-199","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.85826,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 21:47:26","TRTEDTM":"2022-02-19 21:37:55","TRT01SDTM":"2020-01-08 21:47:26","TRT01EDTM":"2021-02-19 15:37:55","TRT02SDTM":"2021-02-19 15:37:55","TRT02EDTM":"2022-02-19 21:37:55","AP01SDTM":"2020-01-08 21:47:26","AP01EDTM":"2021-02-19 15:37:55","AP02SDTM":"2021-02-19 15:37:55","AP02EDTM":"2022-02-19 21:37:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":773,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":779,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7111,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03634,"AVALU":"g/L","BASE2":3.10943,"BASE":3.06962,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07309,"PCHG2":-2.35052,"CHG":-0.03328,"PCHG":-1.08421,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"2","ADTM":"2021-09-01 21:47:26","ADY":602,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-199","SUBJID":"id-199","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.85826,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-07","TRTSDTM":"2020-01-08 21:47:26","TRTEDTM":"2022-02-19 21:37:55","TRT01SDTM":"2020-01-08 21:47:26","TRT01EDTM":"2021-02-19 15:37:55","TRT02SDTM":"2021-02-19 15:37:55","TRT02EDTM":"2022-02-19 21:37:55","AP01SDTM":"2020-01-08 21:47:26","AP01EDTM":"2021-02-19 15:37:55","AP02SDTM":"2021-02-19 15:37:55","AP02EDTM":"2022-02-19 21:37:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":773,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":779,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6568,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88246,"AVALU":"g/L","BASE2":3.10943,"BASE":3.06962,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.22697,"PCHG2":-7.29937,"CHG":-0.18716,"PCHG":-6.09723,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-11-10 21:47:26","ADY":672,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-208","SUBJID":"id-208","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.5165,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-27","TRTSDTM":"2020-07-31 15:15:03","TRTEDTM":"2023-08-01 09:15:03","TRT01SDTM":"2020-07-31 15:15:03","TRT01EDTM":"2022-08-01 03:15:03","TRT02SDTM":"2022-08-01 03:15:03","TRT02EDTM":"2023-08-01 09:15:03","AP01SDTM":"2020-07-31 15:15:03","AP01EDTM":"2022-08-01 03:15:03","AP02SDTM":"2022-08-01 03:15:03","AP02EDTM":"2023-08-01 09:15:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7767,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.33702,"AVALU":"U/L","BASE2":22.33702,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-15 15:15:03","ADY":380,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-208","SUBJID":"id-208","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.5165,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-27","TRTSDTM":"2020-07-31 15:15:03","TRTEDTM":"2023-08-01 09:15:03","TRT01SDTM":"2020-07-31 15:15:03","TRT01EDTM":"2022-08-01 03:15:03","TRT02SDTM":"2022-08-01 03:15:03","TRT02EDTM":"2023-08-01 09:15:03","AP01SDTM":"2020-07-31 15:15:03","AP01EDTM":"2022-08-01 03:15:03","AP02SDTM":"2022-08-01 03:15:03","AP02EDTM":"2023-08-01 09:15:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7687,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.93135,"AVALU":"U/L","BASE2":22.33702,"BASE":9.93135,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-12.40567,"PCHG2":-55.53862,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-18 15:15:03","ADY":567,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-208","SUBJID":"id-208","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.5165,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-27","TRTSDTM":"2020-07-31 15:15:03","TRTEDTM":"2023-08-01 09:15:03","TRT01SDTM":"2020-07-31 15:15:03","TRT01EDTM":"2022-08-01 03:15:03","TRT02SDTM":"2022-08-01 03:15:03","TRT02EDTM":"2023-08-01 09:15:03","AP01SDTM":"2020-07-31 15:15:03","AP01EDTM":"2022-08-01 03:15:03","AP02SDTM":"2022-08-01 03:15:03","AP02EDTM":"2023-08-01 09:15:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":367,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.6913,"AVALU":"U/L","BASE2":22.33702,"BASE":9.93135,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.64572,"PCHG2":-52.1364,"CHG":0.75996,"PCHG":7.65208,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-14 15:15:03","ADY":744,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-208","SUBJID":"id-208","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.5165,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-27","TRTSDTM":"2020-07-31 15:15:03","TRTEDTM":"2023-08-01 09:15:03","TRT01SDTM":"2020-07-31 15:15:03","TRT01EDTM":"2022-08-01 03:15:03","TRT02SDTM":"2022-08-01 03:15:03","TRT02EDTM":"2023-08-01 09:15:03","AP01SDTM":"2020-07-31 15:15:03","AP01EDTM":"2022-08-01 03:15:03","AP02SDTM":"2022-08-01 03:15:03","AP02EDTM":"2023-08-01 09:15:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6940,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.45799,"AVALU":"U/L","BASE2":22.33702,"BASE":9.93135,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.12097,"PCHG2":13.97219,"CHG":15.52665,"PCHG":156.33978,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-01 15:15:03","ADY":943,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-208","SUBJID":"id-208","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.5165,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-27","TRTSDTM":"2020-07-31 15:15:03","TRTEDTM":"2023-08-01 09:15:03","TRT01SDTM":"2020-07-31 15:15:03","TRT01EDTM":"2022-08-01 03:15:03","TRT02SDTM":"2022-08-01 03:15:03","TRT02EDTM":"2023-08-01 09:15:03","AP01SDTM":"2020-07-31 15:15:03","AP01EDTM":"2022-08-01 03:15:03","AP02SDTM":"2022-08-01 03:15:03","AP02EDTM":"2023-08-01 09:15:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6012,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.30833,"AVALU":"U/L","BASE2":22.33702,"BASE":9.93135,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.02869,"PCHG2":-44.89718,"CHG":2.37698,"PCHG":23.93413,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-04 15:15:03","ADY":946,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-208","SUBJID":"id-208","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.5165,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-27","TRTSDTM":"2020-07-31 15:15:03","TRTEDTM":"2023-08-01 09:15:03","TRT01SDTM":"2020-07-31 15:15:03","TRT01EDTM":"2022-08-01 03:15:03","TRT02SDTM":"2022-08-01 03:15:03","TRT02EDTM":"2023-08-01 09:15:03","AP01SDTM":"2020-07-31 15:15:03","AP01EDTM":"2022-08-01 03:15:03","AP02SDTM":"2022-08-01 03:15:03","AP02EDTM":"2023-08-01 09:15:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6477,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.54989,"AVALU":"U/L","BASE2":22.33702,"BASE":9.93135,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.21286,"PCHG2":23.33733,"CHG":17.61854,"PCHG":177.40332,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-19 15:15:03","ADY":992,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-208","SUBJID":"id-208","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.5165,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-27","TRTSDTM":"2020-07-31 15:15:03","TRTEDTM":"2023-08-01 09:15:03","TRT01SDTM":"2020-07-31 15:15:03","TRT01EDTM":"2022-08-01 03:15:03","TRT02SDTM":"2022-08-01 03:15:03","TRT02EDTM":"2023-08-01 09:15:03","AP01SDTM":"2020-07-31 15:15:03","AP01EDTM":"2022-08-01 03:15:03","AP02SDTM":"2022-08-01 03:15:03","AP02EDTM":"2023-08-01 09:15:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7260,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.07963,"AVALU":"U/L","BASE2":22.33702,"BASE":9.93135,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.74261,"PCHG2":21.23207,"CHG":17.14829,"PCHG":172.66828,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-22 15:15:03","ADY":1086,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-208","SUBJID":"id-208","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.5165,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-27","TRTSDTM":"2020-07-31 15:15:03","TRTEDTM":"2023-08-01 09:15:03","TRT01SDTM":"2020-07-31 15:15:03","TRT01EDTM":"2022-08-01 03:15:03","TRT02SDTM":"2022-08-01 03:15:03","TRT02EDTM":"2023-08-01 09:15:03","AP01SDTM":"2020-07-31 15:15:03","AP01EDTM":"2022-08-01 03:15:03","AP02SDTM":"2022-08-01 03:15:03","AP02EDTM":"2023-08-01 09:15:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2510,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.11051,"AVALU":"mg/L","BASE2":9.11051,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-15 15:15:03","ADY":380,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-208","SUBJID":"id-208","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.5165,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-27","TRTSDTM":"2020-07-31 15:15:03","TRTEDTM":"2023-08-01 09:15:03","TRT01SDTM":"2020-07-31 15:15:03","TRT01EDTM":"2022-08-01 03:15:03","TRT02SDTM":"2022-08-01 03:15:03","TRT02EDTM":"2023-08-01 09:15:03","AP01SDTM":"2020-07-31 15:15:03","AP01EDTM":"2022-08-01 03:15:03","AP02SDTM":"2022-08-01 03:15:03","AP02EDTM":"2023-08-01 09:15:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1765,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.28928,"AVALU":"mg/L","BASE2":9.11051,"BASE":9.28928,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.17877,"PCHG2":1.96225,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-18 15:15:03","ADY":567,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-208","SUBJID":"id-208","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.5165,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-27","TRTSDTM":"2020-07-31 15:15:03","TRTEDTM":"2023-08-01 09:15:03","TRT01SDTM":"2020-07-31 15:15:03","TRT01EDTM":"2022-08-01 03:15:03","TRT02SDTM":"2022-08-01 03:15:03","TRT02EDTM":"2023-08-01 09:15:03","AP01SDTM":"2020-07-31 15:15:03","AP01EDTM":"2022-08-01 03:15:03","AP02SDTM":"2022-08-01 03:15:03","AP02EDTM":"2023-08-01 09:15:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5198,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.39246,"AVALU":"mg/L","BASE2":9.11051,"BASE":9.28928,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.71805,"PCHG2":-7.88156,"CHG":-0.89682,"PCHG":-9.65436,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-14 15:15:03","ADY":744,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-208","SUBJID":"id-208","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.5165,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-27","TRTSDTM":"2020-07-31 15:15:03","TRTEDTM":"2023-08-01 09:15:03","TRT01SDTM":"2020-07-31 15:15:03","TRT01EDTM":"2022-08-01 03:15:03","TRT02SDTM":"2022-08-01 03:15:03","TRT02EDTM":"2023-08-01 09:15:03","AP01SDTM":"2020-07-31 15:15:03","AP01EDTM":"2022-08-01 03:15:03","AP02SDTM":"2022-08-01 03:15:03","AP02EDTM":"2023-08-01 09:15:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2603,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.20887,"AVALU":"mg/L","BASE2":9.11051,"BASE":9.28928,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.09836,"PCHG2":12.05597,"CHG":0.91959,"PCHG":9.89947,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2023-03-01 15:15:03","ADY":943,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-208","SUBJID":"id-208","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.5165,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-27","TRTSDTM":"2020-07-31 15:15:03","TRTEDTM":"2023-08-01 09:15:03","TRT01SDTM":"2020-07-31 15:15:03","TRT01EDTM":"2022-08-01 03:15:03","TRT02SDTM":"2022-08-01 03:15:03","TRT02EDTM":"2023-08-01 09:15:03","AP01SDTM":"2020-07-31 15:15:03","AP01EDTM":"2022-08-01 03:15:03","AP02SDTM":"2022-08-01 03:15:03","AP02EDTM":"2023-08-01 09:15:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7864,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.58465,"AVALU":"mg/L","BASE2":9.11051,"BASE":9.28928,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.47414,"PCHG2":5.20432,"CHG":0.29537,"PCHG":3.17968,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-04 15:15:03","ADY":946,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-208","SUBJID":"id-208","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.5165,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-27","TRTSDTM":"2020-07-31 15:15:03","TRTEDTM":"2023-08-01 09:15:03","TRT01SDTM":"2020-07-31 15:15:03","TRT01EDTM":"2022-08-01 03:15:03","TRT02SDTM":"2022-08-01 03:15:03","TRT02EDTM":"2023-08-01 09:15:03","AP01SDTM":"2020-07-31 15:15:03","AP01EDTM":"2022-08-01 03:15:03","AP02SDTM":"2022-08-01 03:15:03","AP02EDTM":"2023-08-01 09:15:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6422,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.16069,"AVALU":"mg/L","BASE2":9.11051,"BASE":9.28928,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.94982,"PCHG2":-21.40191,"CHG":-2.12859,"PCHG":-22.91451,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2023-04-19 15:15:03","ADY":992,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-208","SUBJID":"id-208","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.5165,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-27","TRTSDTM":"2020-07-31 15:15:03","TRTEDTM":"2023-08-01 09:15:03","TRT01SDTM":"2020-07-31 15:15:03","TRT01EDTM":"2022-08-01 03:15:03","TRT02SDTM":"2022-08-01 03:15:03","TRT02EDTM":"2023-08-01 09:15:03","AP01SDTM":"2020-07-31 15:15:03","AP01EDTM":"2022-08-01 03:15:03","AP02SDTM":"2022-08-01 03:15:03","AP02EDTM":"2023-08-01 09:15:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1482,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.74391,"AVALU":"mg/L","BASE2":9.11051,"BASE":9.28928,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.36661,"PCHG2":-4.02398,"CHG":-0.54538,"PCHG":-5.87103,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-22 15:15:03","ADY":1086,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-208","SUBJID":"id-208","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.5165,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-27","TRTSDTM":"2020-07-31 15:15:03","TRTEDTM":"2023-08-01 09:15:03","TRT01SDTM":"2020-07-31 15:15:03","TRT01EDTM":"2022-08-01 03:15:03","TRT02SDTM":"2022-08-01 03:15:03","TRT02EDTM":"2023-08-01 09:15:03","AP01SDTM":"2020-07-31 15:15:03","AP01EDTM":"2022-08-01 03:15:03","AP02SDTM":"2022-08-01 03:15:03","AP02EDTM":"2023-08-01 09:15:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1638,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9361,"AVALU":"g/L","BASE2":2.9361,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-08-15 15:15:03","ADY":380,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-208","SUBJID":"id-208","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.5165,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-27","TRTSDTM":"2020-07-31 15:15:03","TRTEDTM":"2023-08-01 09:15:03","TRT01SDTM":"2020-07-31 15:15:03","TRT01EDTM":"2022-08-01 03:15:03","TRT02SDTM":"2022-08-01 03:15:03","TRT02EDTM":"2023-08-01 09:15:03","AP01SDTM":"2020-07-31 15:15:03","AP01EDTM":"2022-08-01 03:15:03","AP02SDTM":"2022-08-01 03:15:03","AP02EDTM":"2023-08-01 09:15:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7060,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04058,"AVALU":"g/L","BASE2":2.9361,"BASE":3.04058,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.10448,"PCHG2":3.55829,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2022-02-18 15:15:03","ADY":567,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-208","SUBJID":"id-208","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.5165,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-27","TRTSDTM":"2020-07-31 15:15:03","TRTEDTM":"2023-08-01 09:15:03","TRT01SDTM":"2020-07-31 15:15:03","TRT01EDTM":"2022-08-01 03:15:03","TRT02SDTM":"2022-08-01 03:15:03","TRT02EDTM":"2023-08-01 09:15:03","AP01SDTM":"2020-07-31 15:15:03","AP01EDTM":"2022-08-01 03:15:03","AP02SDTM":"2022-08-01 03:15:03","AP02EDTM":"2023-08-01 09:15:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6789,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76484,"AVALU":"g/L","BASE2":2.9361,"BASE":3.04058,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17127,"PCHG2":-5.83309,"CHG":-0.27574,"PCHG":-9.06869,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-08-14 15:15:03","ADY":744,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-208","SUBJID":"id-208","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.5165,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-27","TRTSDTM":"2020-07-31 15:15:03","TRTEDTM":"2023-08-01 09:15:03","TRT01SDTM":"2020-07-31 15:15:03","TRT01EDTM":"2022-08-01 03:15:03","TRT02SDTM":"2022-08-01 03:15:03","TRT02EDTM":"2023-08-01 09:15:03","AP01SDTM":"2020-07-31 15:15:03","AP01EDTM":"2022-08-01 03:15:03","AP02SDTM":"2022-08-01 03:15:03","AP02EDTM":"2023-08-01 09:15:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7549,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96053,"AVALU":"g/L","BASE2":2.9361,"BASE":3.04058,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02442,"PCHG2":0.8318,"CHG":-0.08005,"PCHG":-2.63281,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2023-03-01 15:15:03","ADY":943,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-208","SUBJID":"id-208","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.5165,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-27","TRTSDTM":"2020-07-31 15:15:03","TRTEDTM":"2023-08-01 09:15:03","TRT01SDTM":"2020-07-31 15:15:03","TRT01EDTM":"2022-08-01 03:15:03","TRT02SDTM":"2022-08-01 03:15:03","TRT02EDTM":"2023-08-01 09:15:03","AP01SDTM":"2020-07-31 15:15:03","AP01EDTM":"2022-08-01 03:15:03","AP02SDTM":"2022-08-01 03:15:03","AP02EDTM":"2023-08-01 09:15:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4559,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80124,"AVALU":"g/L","BASE2":2.9361,"BASE":3.04058,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13487,"PCHG2":-4.59347,"CHG":-0.23934,"PCHG":-7.87166,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2023-03-04 15:15:03","ADY":946,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-208","SUBJID":"id-208","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.5165,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-27","TRTSDTM":"2020-07-31 15:15:03","TRTEDTM":"2023-08-01 09:15:03","TRT01SDTM":"2020-07-31 15:15:03","TRT01EDTM":"2022-08-01 03:15:03","TRT02SDTM":"2022-08-01 03:15:03","TRT02EDTM":"2023-08-01 09:15:03","AP01SDTM":"2020-07-31 15:15:03","AP01EDTM":"2022-08-01 03:15:03","AP02SDTM":"2022-08-01 03:15:03","AP02EDTM":"2023-08-01 09:15:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4473,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78991,"AVALU":"g/L","BASE2":2.9361,"BASE":3.04058,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14619,"PCHG2":-4.97906,"CHG":-0.25067,"PCHG":-8.24401,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2023-04-19 15:15:03","ADY":992,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-208","SUBJID":"id-208","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.5165,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-27","TRTSDTM":"2020-07-31 15:15:03","TRTEDTM":"2023-08-01 09:15:03","TRT01SDTM":"2020-07-31 15:15:03","TRT01EDTM":"2022-08-01 03:15:03","TRT02SDTM":"2022-08-01 03:15:03","TRT02EDTM":"2023-08-01 09:15:03","AP01SDTM":"2020-07-31 15:15:03","AP01EDTM":"2022-08-01 03:15:03","AP02SDTM":"2022-08-01 03:15:03","AP02EDTM":"2023-08-01 09:15:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3419,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81436,"AVALU":"g/L","BASE2":2.9361,"BASE":3.04058,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12175,"PCHG2":-4.1466,"CHG":-0.22622,"PCHG":-7.44014,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2023-07-22 15:15:03","ADY":1086,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-212","SUBJID":"id-212","SITEID":"CHN-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.12569,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-28","TRTSDTM":"2020-12-30 06:40:35","TRTEDTM":"2023-12-31 00:40:35","TRT01SDTM":"2020-12-30 06:40:35","TRT01EDTM":"2022-12-30 18:40:35","TRT02SDTM":"2022-12-30 18:40:35","TRT02EDTM":"2023-12-31 00:40:35","AP01SDTM":"2020-12-30 06:40:35","AP01EDTM":"2022-12-30 18:40:35","AP02SDTM":"2022-12-30 18:40:35","AP02EDTM":"2023-12-31 00:40:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-31","EOSDY":1096,"LSTALVDT":"2024-01-28","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6197,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.32338,"AVALU":"U/L","BASE2":6.32338,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-03-24 06:40:35","ADY":84,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-212","SUBJID":"id-212","SITEID":"CHN-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.12569,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-28","TRTSDTM":"2020-12-30 06:40:35","TRTEDTM":"2023-12-31 00:40:35","TRT01SDTM":"2020-12-30 06:40:35","TRT01EDTM":"2022-12-30 18:40:35","TRT02SDTM":"2022-12-30 18:40:35","TRT02EDTM":"2023-12-31 00:40:35","AP01SDTM":"2020-12-30 06:40:35","AP01EDTM":"2022-12-30 18:40:35","AP02SDTM":"2022-12-30 18:40:35","AP02EDTM":"2023-12-31 00:40:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-31","EOSDY":1096,"LSTALVDT":"2024-01-28","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2588,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.93311,"AVALU":"U/L","BASE2":6.32338,"BASE":8.93311,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.60973,"PCHG2":41.27122,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-16 06:40:35","ADY":107,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-212","SUBJID":"id-212","SITEID":"CHN-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.12569,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-28","TRTSDTM":"2020-12-30 06:40:35","TRTEDTM":"2023-12-31 00:40:35","TRT01SDTM":"2020-12-30 06:40:35","TRT01EDTM":"2022-12-30 18:40:35","TRT02SDTM":"2022-12-30 18:40:35","TRT02EDTM":"2023-12-31 00:40:35","AP01SDTM":"2020-12-30 06:40:35","AP01EDTM":"2022-12-30 18:40:35","AP02SDTM":"2022-12-30 18:40:35","AP02EDTM":"2023-12-31 00:40:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-31","EOSDY":1096,"LSTALVDT":"2024-01-28","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7335,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.53921,"AVALU":"U/L","BASE2":6.32338,"BASE":8.93311,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.21583,"PCHG2":161.55662,"CHG":7.6061,"PCHG":85.14501,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-21 06:40:35","ADY":234,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-212","SUBJID":"id-212","SITEID":"CHN-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.12569,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-28","TRTSDTM":"2020-12-30 06:40:35","TRTEDTM":"2023-12-31 00:40:35","TRT01SDTM":"2020-12-30 06:40:35","TRT01EDTM":"2022-12-30 18:40:35","TRT02SDTM":"2022-12-30 18:40:35","TRT02EDTM":"2023-12-31 00:40:35","AP01SDTM":"2020-12-30 06:40:35","AP01EDTM":"2022-12-30 18:40:35","AP02SDTM":"2022-12-30 18:40:35","AP02EDTM":"2023-12-31 00:40:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-31","EOSDY":1096,"LSTALVDT":"2024-01-28","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1889,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.76503,"AVALU":"U/L","BASE2":6.32338,"BASE":8.93311,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.44166,"PCHG2":22.79883,"CHG":-1.16808,"PCHG":-13.07583,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-14 06:40:35","ADY":319,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-212","SUBJID":"id-212","SITEID":"CHN-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.12569,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-28","TRTSDTM":"2020-12-30 06:40:35","TRTEDTM":"2023-12-31 00:40:35","TRT01SDTM":"2020-12-30 06:40:35","TRT01EDTM":"2022-12-30 18:40:35","TRT02SDTM":"2022-12-30 18:40:35","TRT02EDTM":"2023-12-31 00:40:35","AP01SDTM":"2020-12-30 06:40:35","AP01EDTM":"2022-12-30 18:40:35","AP02SDTM":"2022-12-30 18:40:35","AP02EDTM":"2023-12-31 00:40:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-31","EOSDY":1096,"LSTALVDT":"2024-01-28","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3105,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.70509,"AVALU":"U/L","BASE2":6.32338,"BASE":8.93311,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.38171,"PCHG2":306.50888,"CHG":16.77198,"PCHG":187.75066,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-22 06:40:35","ADY":631,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-212","SUBJID":"id-212","SITEID":"CHN-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.12569,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-28","TRTSDTM":"2020-12-30 06:40:35","TRTEDTM":"2023-12-31 00:40:35","TRT01SDTM":"2020-12-30 06:40:35","TRT01EDTM":"2022-12-30 18:40:35","TRT02SDTM":"2022-12-30 18:40:35","TRT02EDTM":"2023-12-31 00:40:35","AP01SDTM":"2020-12-30 06:40:35","AP01EDTM":"2022-12-30 18:40:35","AP02SDTM":"2022-12-30 18:40:35","AP02EDTM":"2023-12-31 00:40:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-31","EOSDY":1096,"LSTALVDT":"2024-01-28","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3834,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.69537,"AVALU":"U/L","BASE2":6.32338,"BASE":8.93311,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.37199,"PCHG2":179.84046,"CHG":8.76225,"PCHG":98.08738,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-03 06:40:35","ADY":793,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-212","SUBJID":"id-212","SITEID":"CHN-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.12569,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-28","TRTSDTM":"2020-12-30 06:40:35","TRTEDTM":"2023-12-31 00:40:35","TRT01SDTM":"2020-12-30 06:40:35","TRT01EDTM":"2022-12-30 18:40:35","TRT02SDTM":"2022-12-30 18:40:35","TRT02EDTM":"2023-12-31 00:40:35","AP01SDTM":"2020-12-30 06:40:35","AP01EDTM":"2022-12-30 18:40:35","AP02SDTM":"2022-12-30 18:40:35","AP02EDTM":"2023-12-31 00:40:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-31","EOSDY":1096,"LSTALVDT":"2024-01-28","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4455,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.71061,"AVALU":"U/L","BASE2":6.32338,"BASE":8.93311,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.38724,"PCHG2":211.71023,"CHG":10.7775,"PCHG":120.64666,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-06 06:40:35","ADY":918,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-212","SUBJID":"id-212","SITEID":"CHN-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.12569,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-28","TRTSDTM":"2020-12-30 06:40:35","TRTEDTM":"2023-12-31 00:40:35","TRT01SDTM":"2020-12-30 06:40:35","TRT01EDTM":"2022-12-30 18:40:35","TRT02SDTM":"2022-12-30 18:40:35","TRT02EDTM":"2023-12-31 00:40:35","AP01SDTM":"2020-12-30 06:40:35","AP01EDTM":"2022-12-30 18:40:35","AP02SDTM":"2022-12-30 18:40:35","AP02EDTM":"2023-12-31 00:40:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-31","EOSDY":1096,"LSTALVDT":"2024-01-28","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4279,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.14171,"AVALU":"mg/L","BASE2":9.14171,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-24 06:40:35","ADY":84,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-212","SUBJID":"id-212","SITEID":"CHN-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.12569,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-28","TRTSDTM":"2020-12-30 06:40:35","TRTEDTM":"2023-12-31 00:40:35","TRT01SDTM":"2020-12-30 06:40:35","TRT01EDTM":"2022-12-30 18:40:35","TRT02SDTM":"2022-12-30 18:40:35","TRT02EDTM":"2023-12-31 00:40:35","AP01SDTM":"2020-12-30 06:40:35","AP01EDTM":"2022-12-30 18:40:35","AP02SDTM":"2022-12-30 18:40:35","AP02EDTM":"2023-12-31 00:40:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-31","EOSDY":1096,"LSTALVDT":"2024-01-28","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1722,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.73231,"AVALU":"mg/L","BASE2":9.14171,"BASE":8.73231,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.4094,"PCHG2":-4.47839,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-16 06:40:35","ADY":107,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-212","SUBJID":"id-212","SITEID":"CHN-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.12569,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-28","TRTSDTM":"2020-12-30 06:40:35","TRTEDTM":"2023-12-31 00:40:35","TRT01SDTM":"2020-12-30 06:40:35","TRT01EDTM":"2022-12-30 18:40:35","TRT02SDTM":"2022-12-30 18:40:35","TRT02EDTM":"2023-12-31 00:40:35","AP01SDTM":"2020-12-30 06:40:35","AP01EDTM":"2022-12-30 18:40:35","AP02SDTM":"2022-12-30 18:40:35","AP02EDTM":"2023-12-31 00:40:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-31","EOSDY":1096,"LSTALVDT":"2024-01-28","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":116,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.97372,"AVALU":"mg/L","BASE2":9.14171,"BASE":8.73231,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16799,"PCHG2":-1.8376,"CHG":0.24141,"PCHG":2.7646,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-21 06:40:35","ADY":234,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-212","SUBJID":"id-212","SITEID":"CHN-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.12569,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-28","TRTSDTM":"2020-12-30 06:40:35","TRTEDTM":"2023-12-31 00:40:35","TRT01SDTM":"2020-12-30 06:40:35","TRT01EDTM":"2022-12-30 18:40:35","TRT02SDTM":"2022-12-30 18:40:35","TRT02EDTM":"2023-12-31 00:40:35","AP01SDTM":"2020-12-30 06:40:35","AP01EDTM":"2022-12-30 18:40:35","AP02SDTM":"2022-12-30 18:40:35","AP02EDTM":"2023-12-31 00:40:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-31","EOSDY":1096,"LSTALVDT":"2024-01-28","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7575,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.97243,"AVALU":"mg/L","BASE2":9.14171,"BASE":8.73231,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16928,"PCHG2":-1.85171,"CHG":0.24012,"PCHG":2.74983,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-14 06:40:35","ADY":319,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-212","SUBJID":"id-212","SITEID":"CHN-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.12569,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-28","TRTSDTM":"2020-12-30 06:40:35","TRTEDTM":"2023-12-31 00:40:35","TRT01SDTM":"2020-12-30 06:40:35","TRT01EDTM":"2022-12-30 18:40:35","TRT02SDTM":"2022-12-30 18:40:35","TRT02EDTM":"2023-12-31 00:40:35","AP01SDTM":"2020-12-30 06:40:35","AP01EDTM":"2022-12-30 18:40:35","AP02SDTM":"2022-12-30 18:40:35","AP02EDTM":"2023-12-31 00:40:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-31","EOSDY":1096,"LSTALVDT":"2024-01-28","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6525,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.94453,"AVALU":"mg/L","BASE2":9.14171,"BASE":8.73231,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.19718,"PCHG2":-13.0958,"CHG":-0.78778,"PCHG":-9.02143,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-09-22 06:40:35","ADY":631,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-212","SUBJID":"id-212","SITEID":"CHN-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.12569,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-28","TRTSDTM":"2020-12-30 06:40:35","TRTEDTM":"2023-12-31 00:40:35","TRT01SDTM":"2020-12-30 06:40:35","TRT01EDTM":"2022-12-30 18:40:35","TRT02SDTM":"2022-12-30 18:40:35","TRT02EDTM":"2023-12-31 00:40:35","AP01SDTM":"2020-12-30 06:40:35","AP01EDTM":"2022-12-30 18:40:35","AP02SDTM":"2022-12-30 18:40:35","AP02EDTM":"2023-12-31 00:40:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-31","EOSDY":1096,"LSTALVDT":"2024-01-28","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2023,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.56873,"AVALU":"mg/L","BASE2":9.14171,"BASE":8.73231,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.57298,"PCHG2":-6.26777,"CHG":-0.16358,"PCHG":-1.87327,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-03 06:40:35","ADY":793,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-212","SUBJID":"id-212","SITEID":"CHN-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.12569,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-28","TRTSDTM":"2020-12-30 06:40:35","TRTEDTM":"2023-12-31 00:40:35","TRT01SDTM":"2020-12-30 06:40:35","TRT01EDTM":"2022-12-30 18:40:35","TRT02SDTM":"2022-12-30 18:40:35","TRT02EDTM":"2023-12-31 00:40:35","AP01SDTM":"2020-12-30 06:40:35","AP01EDTM":"2022-12-30 18:40:35","AP02SDTM":"2022-12-30 18:40:35","AP02EDTM":"2023-12-31 00:40:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-31","EOSDY":1096,"LSTALVDT":"2024-01-28","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4215,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.39183,"AVALU":"mg/L","BASE2":9.14171,"BASE":8.73231,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.74989,"PCHG2":-8.20291,"CHG":-0.34049,"PCHG":-3.89914,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-06 06:40:35","ADY":918,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-212","SUBJID":"id-212","SITEID":"CHN-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.12569,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-28","TRTSDTM":"2020-12-30 06:40:35","TRTEDTM":"2023-12-31 00:40:35","TRT01SDTM":"2020-12-30 06:40:35","TRT01EDTM":"2022-12-30 18:40:35","TRT02SDTM":"2022-12-30 18:40:35","TRT02EDTM":"2023-12-31 00:40:35","AP01SDTM":"2020-12-30 06:40:35","AP01EDTM":"2022-12-30 18:40:35","AP02SDTM":"2022-12-30 18:40:35","AP02EDTM":"2023-12-31 00:40:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-31","EOSDY":1096,"LSTALVDT":"2024-01-28","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5130,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97482,"AVALU":"g/L","BASE2":2.97482,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"4","ADTM":"2021-03-24 06:40:35","ADY":84,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-212","SUBJID":"id-212","SITEID":"CHN-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.12569,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-28","TRTSDTM":"2020-12-30 06:40:35","TRTEDTM":"2023-12-31 00:40:35","TRT01SDTM":"2020-12-30 06:40:35","TRT01EDTM":"2022-12-30 18:40:35","TRT02SDTM":"2022-12-30 18:40:35","TRT02EDTM":"2023-12-31 00:40:35","AP01SDTM":"2020-12-30 06:40:35","AP01EDTM":"2022-12-30 18:40:35","AP02SDTM":"2022-12-30 18:40:35","AP02EDTM":"2023-12-31 00:40:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-31","EOSDY":1096,"LSTALVDT":"2024-01-28","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7134,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04637,"AVALU":"g/L","BASE2":2.97482,"BASE":3.04637,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.07155,"PCHG2":2.40528,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"4","BTOXGR":"4","ADTM":"2021-04-16 06:40:35","ADY":107,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-212","SUBJID":"id-212","SITEID":"CHN-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.12569,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-28","TRTSDTM":"2020-12-30 06:40:35","TRTEDTM":"2023-12-31 00:40:35","TRT01SDTM":"2020-12-30 06:40:35","TRT01EDTM":"2022-12-30 18:40:35","TRT02SDTM":"2022-12-30 18:40:35","TRT02EDTM":"2023-12-31 00:40:35","AP01SDTM":"2020-12-30 06:40:35","AP01EDTM":"2022-12-30 18:40:35","AP02SDTM":"2022-12-30 18:40:35","AP02EDTM":"2023-12-31 00:40:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-31","EOSDY":1096,"LSTALVDT":"2024-01-28","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8350,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85924,"AVALU":"g/L","BASE2":2.97482,"BASE":3.04637,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11558,"PCHG2":-3.88515,"CHG":-0.18713,"PCHG":-6.14268,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2021-08-21 06:40:35","ADY":234,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-212","SUBJID":"id-212","SITEID":"CHN-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.12569,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-28","TRTSDTM":"2020-12-30 06:40:35","TRTEDTM":"2023-12-31 00:40:35","TRT01SDTM":"2020-12-30 06:40:35","TRT01EDTM":"2022-12-30 18:40:35","TRT02SDTM":"2022-12-30 18:40:35","TRT02EDTM":"2023-12-31 00:40:35","AP01SDTM":"2020-12-30 06:40:35","AP01EDTM":"2022-12-30 18:40:35","AP02SDTM":"2022-12-30 18:40:35","AP02EDTM":"2023-12-31 00:40:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-31","EOSDY":1096,"LSTALVDT":"2024-01-28","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":757,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8027,"AVALU":"g/L","BASE2":2.97482,"BASE":3.04637,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17212,"PCHG2":-5.78583,"CHG":-0.24367,"PCHG":-7.99872,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2021-11-14 06:40:35","ADY":319,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-212","SUBJID":"id-212","SITEID":"CHN-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.12569,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-28","TRTSDTM":"2020-12-30 06:40:35","TRTEDTM":"2023-12-31 00:40:35","TRT01SDTM":"2020-12-30 06:40:35","TRT01EDTM":"2022-12-30 18:40:35","TRT02SDTM":"2022-12-30 18:40:35","TRT02EDTM":"2023-12-31 00:40:35","AP01SDTM":"2020-12-30 06:40:35","AP01EDTM":"2022-12-30 18:40:35","AP02SDTM":"2022-12-30 18:40:35","AP02EDTM":"2023-12-31 00:40:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-31","EOSDY":1096,"LSTALVDT":"2024-01-28","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4390,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99745,"AVALU":"g/L","BASE2":2.97482,"BASE":3.04637,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02264,"PCHG2":0.76092,"CHG":-0.04892,"PCHG":-1.60573,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2022-09-22 06:40:35","ADY":631,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-212","SUBJID":"id-212","SITEID":"CHN-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.12569,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-28","TRTSDTM":"2020-12-30 06:40:35","TRTEDTM":"2023-12-31 00:40:35","TRT01SDTM":"2020-12-30 06:40:35","TRT01EDTM":"2022-12-30 18:40:35","TRT02SDTM":"2022-12-30 18:40:35","TRT02EDTM":"2023-12-31 00:40:35","AP01SDTM":"2020-12-30 06:40:35","AP01EDTM":"2022-12-30 18:40:35","AP02SDTM":"2022-12-30 18:40:35","AP02EDTM":"2023-12-31 00:40:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-31","EOSDY":1096,"LSTALVDT":"2024-01-28","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6935,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7917,"AVALU":"g/L","BASE2":2.97482,"BASE":3.04637,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18312,"PCHG2":-6.15557,"CHG":-0.25467,"PCHG":-8.35977,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2023-03-03 06:40:35","ADY":793,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-212","SUBJID":"id-212","SITEID":"CHN-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.12569,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-28","TRTSDTM":"2020-12-30 06:40:35","TRTEDTM":"2023-12-31 00:40:35","TRT01SDTM":"2020-12-30 06:40:35","TRT01EDTM":"2022-12-30 18:40:35","TRT02SDTM":"2022-12-30 18:40:35","TRT02EDTM":"2023-12-31 00:40:35","AP01SDTM":"2020-12-30 06:40:35","AP01EDTM":"2022-12-30 18:40:35","AP02SDTM":"2022-12-30 18:40:35","AP02EDTM":"2023-12-31 00:40:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-31","EOSDY":1096,"LSTALVDT":"2024-01-28","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1471,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.896,"AVALU":"g/L","BASE2":2.97482,"BASE":3.04637,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07882,"PCHG2":-2.64951,"CHG":-0.15037,"PCHG":-4.93606,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2023-07-06 06:40:35","ADY":918,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-216","SUBJID":"id-216","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.43058,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-30","TRTSDTM":"2020-10-04 02:51:15","TRTEDTM":"2023-10-04 20:51:15","TRT01SDTM":"2020-10-04 02:51:15","TRT01EDTM":"2022-10-04 14:51:15","TRT02SDTM":"2022-10-04 14:51:15","TRT02EDTM":"2023-10-04 20:51:15","AP01SDTM":"2020-10-04 02:51:15","AP01EDTM":"2022-10-04 14:51:15","AP02SDTM":"2022-10-04 14:51:15","AP02EDTM":"2023-10-04 20:51:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-17","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8016,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.56136,"AVALU":"U/L","BASE2":22.56136,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-16 02:51:15","ADY":43,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-216","SUBJID":"id-216","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.43058,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-30","TRTSDTM":"2020-10-04 02:51:15","TRTEDTM":"2023-10-04 20:51:15","TRT01SDTM":"2020-10-04 02:51:15","TRT01EDTM":"2022-10-04 14:51:15","TRT02SDTM":"2022-10-04 14:51:15","TRT02EDTM":"2023-10-04 20:51:15","AP01SDTM":"2020-10-04 02:51:15","AP01EDTM":"2022-10-04 14:51:15","AP02SDTM":"2022-10-04 14:51:15","AP02EDTM":"2023-10-04 20:51:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-17","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3437,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.02431,"AVALU":"U/L","BASE2":22.56136,"BASE":14.02431,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-8.53705,"PCHG2":-37.83926,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-22 02:51:15","ADY":79,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-216","SUBJID":"id-216","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.43058,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-30","TRTSDTM":"2020-10-04 02:51:15","TRTEDTM":"2023-10-04 20:51:15","TRT01SDTM":"2020-10-04 02:51:15","TRT01EDTM":"2022-10-04 14:51:15","TRT02SDTM":"2022-10-04 14:51:15","TRT02EDTM":"2023-10-04 20:51:15","AP01SDTM":"2020-10-04 02:51:15","AP01EDTM":"2022-10-04 14:51:15","AP02SDTM":"2022-10-04 14:51:15","AP02EDTM":"2023-10-04 20:51:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-17","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7119,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.86015,"AVALU":"U/L","BASE2":22.56136,"BASE":14.02431,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.70121,"PCHG2":-56.2963,"CHG":-4.16416,"PCHG":-29.69244,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-24 02:51:15","ADY":81,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-216","SUBJID":"id-216","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.43058,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-30","TRTSDTM":"2020-10-04 02:51:15","TRTEDTM":"2023-10-04 20:51:15","TRT01SDTM":"2020-10-04 02:51:15","TRT01EDTM":"2022-10-04 14:51:15","TRT02SDTM":"2022-10-04 14:51:15","TRT02EDTM":"2023-10-04 20:51:15","AP01SDTM":"2020-10-04 02:51:15","AP01EDTM":"2022-10-04 14:51:15","AP02SDTM":"2022-10-04 14:51:15","AP02EDTM":"2023-10-04 20:51:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-17","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5954,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.98461,"AVALU":"U/L","BASE2":22.56136,"BASE":14.02431,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.57674,"PCHG2":-38.0152,"CHG":-0.03969,"PCHG":-0.28303,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-01 02:51:15","ADY":120,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-216","SUBJID":"id-216","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.43058,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-30","TRTSDTM":"2020-10-04 02:51:15","TRTEDTM":"2023-10-04 20:51:15","TRT01SDTM":"2020-10-04 02:51:15","TRT01EDTM":"2022-10-04 14:51:15","TRT02SDTM":"2022-10-04 14:51:15","TRT02EDTM":"2023-10-04 20:51:15","AP01SDTM":"2020-10-04 02:51:15","AP01EDTM":"2022-10-04 14:51:15","AP02SDTM":"2022-10-04 14:51:15","AP02EDTM":"2023-10-04 20:51:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-17","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2252,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.35861,"AVALU":"U/L","BASE2":22.56136,"BASE":14.02431,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.20275,"PCHG2":-40.78988,"CHG":-0.6657,"PCHG":-4.74676,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-07 02:51:15","ADY":307,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-216","SUBJID":"id-216","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.43058,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-30","TRTSDTM":"2020-10-04 02:51:15","TRTEDTM":"2023-10-04 20:51:15","TRT01SDTM":"2020-10-04 02:51:15","TRT01EDTM":"2022-10-04 14:51:15","TRT02SDTM":"2022-10-04 14:51:15","TRT02EDTM":"2023-10-04 20:51:15","AP01SDTM":"2020-10-04 02:51:15","AP01EDTM":"2022-10-04 14:51:15","AP02SDTM":"2022-10-04 14:51:15","AP02EDTM":"2023-10-04 20:51:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-17","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3387,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.24245,"AVALU":"U/L","BASE2":22.56136,"BASE":14.02431,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.31891,"PCHG2":-1.41351,"CHG":8.21814,"PCHG":58.5993,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-03 02:51:15","ADY":852,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-216","SUBJID":"id-216","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.43058,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-30","TRTSDTM":"2020-10-04 02:51:15","TRTEDTM":"2023-10-04 20:51:15","TRT01SDTM":"2020-10-04 02:51:15","TRT01EDTM":"2022-10-04 14:51:15","TRT02SDTM":"2022-10-04 14:51:15","TRT02EDTM":"2023-10-04 20:51:15","AP01SDTM":"2020-10-04 02:51:15","AP01EDTM":"2022-10-04 14:51:15","AP02SDTM":"2022-10-04 14:51:15","AP02EDTM":"2023-10-04 20:51:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-17","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2339,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.34826,"AVALU":"U/L","BASE2":22.56136,"BASE":14.02431,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.21309,"PCHG2":-18.67393,"CHG":4.32396,"PCHG":30.83189,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-23 02:51:15","ADY":1084,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-216","SUBJID":"id-216","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.43058,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-30","TRTSDTM":"2020-10-04 02:51:15","TRTEDTM":"2023-10-04 20:51:15","TRT01SDTM":"2020-10-04 02:51:15","TRT01EDTM":"2022-10-04 14:51:15","TRT02SDTM":"2022-10-04 14:51:15","TRT02EDTM":"2023-10-04 20:51:15","AP01SDTM":"2020-10-04 02:51:15","AP01EDTM":"2022-10-04 14:51:15","AP02SDTM":"2022-10-04 14:51:15","AP02EDTM":"2023-10-04 20:51:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-17","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2668,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.07962,"AVALU":"mg/L","BASE2":9.07962,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"4","ADTM":"2020-11-16 02:51:15","ADY":43,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-216","SUBJID":"id-216","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.43058,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-30","TRTSDTM":"2020-10-04 02:51:15","TRTEDTM":"2023-10-04 20:51:15","TRT01SDTM":"2020-10-04 02:51:15","TRT01EDTM":"2022-10-04 14:51:15","TRT02SDTM":"2022-10-04 14:51:15","TRT02EDTM":"2023-10-04 20:51:15","AP01SDTM":"2020-10-04 02:51:15","AP01EDTM":"2022-10-04 14:51:15","AP02SDTM":"2022-10-04 14:51:15","AP02EDTM":"2023-10-04 20:51:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-17","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":789,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.87108,"AVALU":"mg/L","BASE2":9.07962,"BASE":11.87108,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.79146,"PCHG2":30.74428,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"4","BTOXGR":"4","ADTM":"2020-12-22 02:51:15","ADY":79,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-216","SUBJID":"id-216","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.43058,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-30","TRTSDTM":"2020-10-04 02:51:15","TRTEDTM":"2023-10-04 20:51:15","TRT01SDTM":"2020-10-04 02:51:15","TRT01EDTM":"2022-10-04 14:51:15","TRT02SDTM":"2022-10-04 14:51:15","TRT02EDTM":"2023-10-04 20:51:15","AP01SDTM":"2020-10-04 02:51:15","AP01EDTM":"2022-10-04 14:51:15","AP02SDTM":"2022-10-04 14:51:15","AP02EDTM":"2023-10-04 20:51:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-17","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7841,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.43264,"AVALU":"mg/L","BASE2":9.07962,"BASE":11.87108,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.64698,"PCHG2":-7.12561,"CHG":-3.43844,"PCHG":-28.96486,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2020-12-24 02:51:15","ADY":81,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-216","SUBJID":"id-216","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.43058,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-30","TRTSDTM":"2020-10-04 02:51:15","TRTEDTM":"2023-10-04 20:51:15","TRT01SDTM":"2020-10-04 02:51:15","TRT01EDTM":"2022-10-04 14:51:15","TRT02SDTM":"2022-10-04 14:51:15","TRT02EDTM":"2023-10-04 20:51:15","AP01SDTM":"2020-10-04 02:51:15","AP01EDTM":"2022-10-04 14:51:15","AP02SDTM":"2022-10-04 14:51:15","AP02EDTM":"2023-10-04 20:51:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-17","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5911,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.34554,"AVALU":"mg/L","BASE2":9.07962,"BASE":11.87108,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.73408,"PCHG2":-19.09856,"CHG":-4.52554,"PCHG":-38.12239,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-2","BTOXGR":"4","ADTM":"2021-02-01 02:51:15","ADY":120,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-216","SUBJID":"id-216","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.43058,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-30","TRTSDTM":"2020-10-04 02:51:15","TRTEDTM":"2023-10-04 20:51:15","TRT01SDTM":"2020-10-04 02:51:15","TRT01EDTM":"2022-10-04 14:51:15","TRT02SDTM":"2022-10-04 14:51:15","TRT02EDTM":"2023-10-04 20:51:15","AP01SDTM":"2020-10-04 02:51:15","AP01EDTM":"2022-10-04 14:51:15","AP02SDTM":"2022-10-04 14:51:15","AP02EDTM":"2023-10-04 20:51:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-17","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4003,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.92547,"AVALU":"mg/L","BASE2":9.07962,"BASE":11.87108,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.15415,"PCHG2":-12.71147,"CHG":-3.94562,"PCHG":-33.23721,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-1","BTOXGR":"4","ADTM":"2021-08-07 02:51:15","ADY":307,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-216","SUBJID":"id-216","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.43058,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-30","TRTSDTM":"2020-10-04 02:51:15","TRTEDTM":"2023-10-04 20:51:15","TRT01SDTM":"2020-10-04 02:51:15","TRT01EDTM":"2022-10-04 14:51:15","TRT02SDTM":"2022-10-04 14:51:15","TRT02EDTM":"2023-10-04 20:51:15","AP01SDTM":"2020-10-04 02:51:15","AP01EDTM":"2022-10-04 14:51:15","AP02SDTM":"2022-10-04 14:51:15","AP02EDTM":"2023-10-04 20:51:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-17","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6467,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.13672,"AVALU":"mg/L","BASE2":9.07962,"BASE":11.87108,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.0571,"PCHG2":22.65621,"CHG":-0.73437,"PCHG":-6.18618,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"4","BTOXGR":"4","ADTM":"2023-02-03 02:51:15","ADY":852,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-216","SUBJID":"id-216","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.43058,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-30","TRTSDTM":"2020-10-04 02:51:15","TRTEDTM":"2023-10-04 20:51:15","TRT01SDTM":"2020-10-04 02:51:15","TRT01EDTM":"2022-10-04 14:51:15","TRT02SDTM":"2022-10-04 14:51:15","TRT02EDTM":"2023-10-04 20:51:15","AP01SDTM":"2020-10-04 02:51:15","AP01EDTM":"2022-10-04 14:51:15","AP02SDTM":"2022-10-04 14:51:15","AP02EDTM":"2023-10-04 20:51:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-17","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2489,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.15214,"AVALU":"mg/L","BASE2":9.07962,"BASE":11.87108,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07252,"PCHG2":0.7987,"CHG":-2.71895,"PCHG":-22.90394,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2023-09-23 02:51:15","ADY":1084,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-216","SUBJID":"id-216","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.43058,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-30","TRTSDTM":"2020-10-04 02:51:15","TRTEDTM":"2023-10-04 20:51:15","TRT01SDTM":"2020-10-04 02:51:15","TRT01EDTM":"2022-10-04 14:51:15","TRT02SDTM":"2022-10-04 14:51:15","TRT02EDTM":"2023-10-04 20:51:15","AP01SDTM":"2020-10-04 02:51:15","AP01EDTM":"2022-10-04 14:51:15","AP02SDTM":"2022-10-04 14:51:15","AP02EDTM":"2023-10-04 20:51:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-17","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5589,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74636,"AVALU":"g/L","BASE2":2.74636,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-16 02:51:15","ADY":43,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-216","SUBJID":"id-216","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.43058,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-30","TRTSDTM":"2020-10-04 02:51:15","TRTEDTM":"2023-10-04 20:51:15","TRT01SDTM":"2020-10-04 02:51:15","TRT01EDTM":"2022-10-04 14:51:15","TRT02SDTM":"2022-10-04 14:51:15","TRT02EDTM":"2023-10-04 20:51:15","AP01SDTM":"2020-10-04 02:51:15","AP01EDTM":"2022-10-04 14:51:15","AP02SDTM":"2022-10-04 14:51:15","AP02EDTM":"2023-10-04 20:51:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-17","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3351,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86287,"AVALU":"g/L","BASE2":2.74636,"BASE":2.86287,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.11651,"PCHG2":4.24238,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-22 02:51:15","ADY":79,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-216","SUBJID":"id-216","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.43058,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-30","TRTSDTM":"2020-10-04 02:51:15","TRTEDTM":"2023-10-04 20:51:15","TRT01SDTM":"2020-10-04 02:51:15","TRT01EDTM":"2022-10-04 14:51:15","TRT02SDTM":"2022-10-04 14:51:15","TRT02EDTM":"2023-10-04 20:51:15","AP01SDTM":"2020-10-04 02:51:15","AP01EDTM":"2022-10-04 14:51:15","AP02SDTM":"2022-10-04 14:51:15","AP02EDTM":"2023-10-04 20:51:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-17","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2365,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.10156,"AVALU":"g/L","BASE2":2.74636,"BASE":2.86287,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.3552,"PCHG2":12.93355,"CHG":0.23869,"PCHG":8.33747,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-12-24 02:51:15","ADY":81,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-216","SUBJID":"id-216","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.43058,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-30","TRTSDTM":"2020-10-04 02:51:15","TRTEDTM":"2023-10-04 20:51:15","TRT01SDTM":"2020-10-04 02:51:15","TRT01EDTM":"2022-10-04 14:51:15","TRT02SDTM":"2022-10-04 14:51:15","TRT02EDTM":"2023-10-04 20:51:15","AP01SDTM":"2020-10-04 02:51:15","AP01EDTM":"2022-10-04 14:51:15","AP02SDTM":"2022-10-04 14:51:15","AP02EDTM":"2023-10-04 20:51:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-17","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4780,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78699,"AVALU":"g/L","BASE2":2.74636,"BASE":2.86287,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04062,"PCHG2":1.47919,"CHG":-0.07589,"PCHG":-2.65073,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-01 02:51:15","ADY":120,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-216","SUBJID":"id-216","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.43058,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-30","TRTSDTM":"2020-10-04 02:51:15","TRTEDTM":"2023-10-04 20:51:15","TRT01SDTM":"2020-10-04 02:51:15","TRT01EDTM":"2022-10-04 14:51:15","TRT02SDTM":"2022-10-04 14:51:15","TRT02EDTM":"2023-10-04 20:51:15","AP01SDTM":"2020-10-04 02:51:15","AP01EDTM":"2022-10-04 14:51:15","AP02SDTM":"2022-10-04 14:51:15","AP02EDTM":"2023-10-04 20:51:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-17","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1629,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79721,"AVALU":"g/L","BASE2":2.74636,"BASE":2.86287,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05085,"PCHG2":1.85155,"CHG":-0.06566,"PCHG":-2.29353,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-07 02:51:15","ADY":307,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-216","SUBJID":"id-216","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.43058,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-30","TRTSDTM":"2020-10-04 02:51:15","TRTEDTM":"2023-10-04 20:51:15","TRT01SDTM":"2020-10-04 02:51:15","TRT01EDTM":"2022-10-04 14:51:15","TRT02SDTM":"2022-10-04 14:51:15","TRT02EDTM":"2023-10-04 20:51:15","AP01SDTM":"2020-10-04 02:51:15","AP01EDTM":"2022-10-04 14:51:15","AP02SDTM":"2022-10-04 14:51:15","AP02EDTM":"2023-10-04 20:51:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-17","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7352,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97814,"AVALU":"g/L","BASE2":2.74636,"BASE":2.86287,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.23178,"PCHG2":8.43955,"CHG":0.11527,"PCHG":4.02636,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-03 02:51:15","ADY":852,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-216","SUBJID":"id-216","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.43058,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-30","TRTSDTM":"2020-10-04 02:51:15","TRTEDTM":"2023-10-04 20:51:15","TRT01SDTM":"2020-10-04 02:51:15","TRT01EDTM":"2022-10-04 14:51:15","TRT02SDTM":"2022-10-04 14:51:15","TRT02EDTM":"2023-10-04 20:51:15","AP01SDTM":"2020-10-04 02:51:15","AP01EDTM":"2022-10-04 14:51:15","AP02SDTM":"2022-10-04 14:51:15","AP02EDTM":"2023-10-04 20:51:15","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-17","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6163,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79763,"AVALU":"g/L","BASE2":2.74636,"BASE":2.86287,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05127,"PCHG2":1.86683,"CHG":-0.06524,"PCHG":-2.27887,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-23 02:51:15","ADY":1084,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-227","SUBJID":"id-227","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.1904,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-07","TRTSDTM":"2019-04-09 23:09:23","TRTEDTM":"2022-02-17 14:54:24","TRT01SDTM":"2019-04-09 23:09:23","TRT01EDTM":"2021-02-17 08:54:24","TRT02SDTM":"2021-02-17 08:54:24","TRT02EDTM":"2022-02-17 14:54:24","AP01SDTM":"2019-04-09 23:09:23","AP01EDTM":"2021-02-17 08:54:24","AP02SDTM":"2021-02-17 08:54:24","AP02EDTM":"2022-02-17 14:54:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1045,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-15","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6708,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.19826,"AVALU":"U/L","BASE2":24.19826,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-29 23:09:23","ADY":264,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-227","SUBJID":"id-227","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.1904,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-07","TRTSDTM":"2019-04-09 23:09:23","TRTEDTM":"2022-02-17 14:54:24","TRT01SDTM":"2019-04-09 23:09:23","TRT01EDTM":"2021-02-17 08:54:24","TRT02SDTM":"2021-02-17 08:54:24","TRT02EDTM":"2022-02-17 14:54:24","AP01SDTM":"2019-04-09 23:09:23","AP01EDTM":"2021-02-17 08:54:24","AP02SDTM":"2021-02-17 08:54:24","AP02EDTM":"2022-02-17 14:54:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1045,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-15","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7444,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.28972,"AVALU":"U/L","BASE2":24.19826,"BASE":23.28972,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.90854,"PCHG2":-3.75457,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-20 23:09:23","ADY":286,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-227","SUBJID":"id-227","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.1904,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-07","TRTSDTM":"2019-04-09 23:09:23","TRTEDTM":"2022-02-17 14:54:24","TRT01SDTM":"2019-04-09 23:09:23","TRT01EDTM":"2021-02-17 08:54:24","TRT02SDTM":"2021-02-17 08:54:24","TRT02EDTM":"2022-02-17 14:54:24","AP01SDTM":"2019-04-09 23:09:23","AP01EDTM":"2021-02-17 08:54:24","AP02SDTM":"2021-02-17 08:54:24","AP02EDTM":"2022-02-17 14:54:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1045,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-15","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3682,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.122,"AVALU":"U/L","BASE2":24.19826,"BASE":23.28972,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.07626,"PCHG2":-54.03802,"CHG":-12.16772,"PCHG":-52.24502,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-16 23:09:23","ADY":403,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-227","SUBJID":"id-227","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.1904,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-07","TRTSDTM":"2019-04-09 23:09:23","TRTEDTM":"2022-02-17 14:54:24","TRT01SDTM":"2019-04-09 23:09:23","TRT01EDTM":"2021-02-17 08:54:24","TRT02SDTM":"2021-02-17 08:54:24","TRT02EDTM":"2022-02-17 14:54:24","AP01SDTM":"2019-04-09 23:09:23","AP01EDTM":"2021-02-17 08:54:24","AP02SDTM":"2021-02-17 08:54:24","AP02EDTM":"2022-02-17 14:54:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1045,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-15","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4802,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.44774,"AVALU":"U/L","BASE2":24.19826,"BASE":23.28972,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.75052,"PCHG2":-32.02925,"CHG":-6.84198,"PCHG":-29.37769,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-07 23:09:23","ADY":608,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-227","SUBJID":"id-227","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.1904,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-07","TRTSDTM":"2019-04-09 23:09:23","TRTEDTM":"2022-02-17 14:54:24","TRT01SDTM":"2019-04-09 23:09:23","TRT01EDTM":"2021-02-17 08:54:24","TRT02SDTM":"2021-02-17 08:54:24","TRT02EDTM":"2022-02-17 14:54:24","AP01SDTM":"2019-04-09 23:09:23","AP01EDTM":"2021-02-17 08:54:24","AP02SDTM":"2021-02-17 08:54:24","AP02EDTM":"2022-02-17 14:54:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1045,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-15","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6626,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.99169,"AVALU":"U/L","BASE2":24.19826,"BASE":23.28972,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.20657,"PCHG2":-29.78135,"CHG":-6.29803,"PCHG":-27.0421,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-11 23:09:23","ADY":612,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-227","SUBJID":"id-227","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.1904,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-07","TRTSDTM":"2019-04-09 23:09:23","TRTEDTM":"2022-02-17 14:54:24","TRT01SDTM":"2019-04-09 23:09:23","TRT01EDTM":"2021-02-17 08:54:24","TRT02SDTM":"2021-02-17 08:54:24","TRT02EDTM":"2022-02-17 14:54:24","AP01SDTM":"2019-04-09 23:09:23","AP01EDTM":"2021-02-17 08:54:24","AP02SDTM":"2021-02-17 08:54:24","AP02EDTM":"2022-02-17 14:54:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1045,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-15","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5220,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.26826,"AVALU":"U/L","BASE2":24.19826,"BASE":23.28972,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.93,"PCHG2":-53.43358,"CHG":-12.02145,"PCHG":-51.61701,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-12 23:09:23","ADY":795,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-227","SUBJID":"id-227","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.1904,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-07","TRTSDTM":"2019-04-09 23:09:23","TRTEDTM":"2022-02-17 14:54:24","TRT01SDTM":"2019-04-09 23:09:23","TRT01EDTM":"2021-02-17 08:54:24","TRT02SDTM":"2021-02-17 08:54:24","TRT02EDTM":"2022-02-17 14:54:24","AP01SDTM":"2019-04-09 23:09:23","AP01EDTM":"2021-02-17 08:54:24","AP02SDTM":"2021-02-17 08:54:24","AP02EDTM":"2022-02-17 14:54:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1045,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-15","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5039,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.92145,"AVALU":"U/L","BASE2":24.19826,"BASE":23.28972,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.27681,"PCHG2":-46.60175,"CHG":-10.36827,"PCHG":-44.51866,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-29 23:09:23","ADY":934,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-227","SUBJID":"id-227","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.1904,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-07","TRTSDTM":"2019-04-09 23:09:23","TRTEDTM":"2022-02-17 14:54:24","TRT01SDTM":"2019-04-09 23:09:23","TRT01EDTM":"2021-02-17 08:54:24","TRT02SDTM":"2021-02-17 08:54:24","TRT02EDTM":"2022-02-17 14:54:24","AP01SDTM":"2019-04-09 23:09:23","AP01EDTM":"2021-02-17 08:54:24","AP02SDTM":"2021-02-17 08:54:24","AP02EDTM":"2022-02-17 14:54:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1045,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-15","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3286,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.8709,"AVALU":"mg/L","BASE2":9.8709,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-3","ADTM":"2019-12-29 23:09:23","ADY":264,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-227","SUBJID":"id-227","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.1904,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-07","TRTSDTM":"2019-04-09 23:09:23","TRTEDTM":"2022-02-17 14:54:24","TRT01SDTM":"2019-04-09 23:09:23","TRT01EDTM":"2021-02-17 08:54:24","TRT02SDTM":"2021-02-17 08:54:24","TRT02EDTM":"2022-02-17 14:54:24","AP01SDTM":"2019-04-09 23:09:23","AP01EDTM":"2021-02-17 08:54:24","AP02SDTM":"2021-02-17 08:54:24","AP02EDTM":"2022-02-17 14:54:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1045,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-15","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":711,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.38324,"AVALU":"mg/L","BASE2":9.8709,"BASE":7.38324,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.48767,"PCHG2":-25.20202,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2020-01-20 23:09:23","ADY":286,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-227","SUBJID":"id-227","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.1904,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-07","TRTSDTM":"2019-04-09 23:09:23","TRTEDTM":"2022-02-17 14:54:24","TRT01SDTM":"2019-04-09 23:09:23","TRT01EDTM":"2021-02-17 08:54:24","TRT02SDTM":"2021-02-17 08:54:24","TRT02EDTM":"2022-02-17 14:54:24","AP01SDTM":"2019-04-09 23:09:23","AP01EDTM":"2021-02-17 08:54:24","AP02SDTM":"2021-02-17 08:54:24","AP02EDTM":"2022-02-17 14:54:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1045,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-15","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":53,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.67834,"AVALU":"mg/L","BASE2":9.8709,"BASE":7.38324,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.19256,"PCHG2":-22.2124,"CHG":0.2951,"PCHG":3.99693,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2020-05-16 23:09:23","ADY":403,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-227","SUBJID":"id-227","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.1904,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-07","TRTSDTM":"2019-04-09 23:09:23","TRTEDTM":"2022-02-17 14:54:24","TRT01SDTM":"2019-04-09 23:09:23","TRT01EDTM":"2021-02-17 08:54:24","TRT02SDTM":"2021-02-17 08:54:24","TRT02EDTM":"2022-02-17 14:54:24","AP01SDTM":"2019-04-09 23:09:23","AP01EDTM":"2021-02-17 08:54:24","AP02SDTM":"2021-02-17 08:54:24","AP02EDTM":"2022-02-17 14:54:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1045,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-15","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1204,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.12021,"AVALU":"mg/L","BASE2":9.8709,"BASE":7.38324,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.2493,"PCHG2":2.52562,"CHG":2.73697,"PCHG":37.07004,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"1","BTOXGR":"-3","ADTM":"2020-12-07 23:09:23","ADY":608,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-227","SUBJID":"id-227","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.1904,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-07","TRTSDTM":"2019-04-09 23:09:23","TRTEDTM":"2022-02-17 14:54:24","TRT01SDTM":"2019-04-09 23:09:23","TRT01EDTM":"2021-02-17 08:54:24","TRT02SDTM":"2021-02-17 08:54:24","TRT02EDTM":"2022-02-17 14:54:24","AP01SDTM":"2019-04-09 23:09:23","AP01EDTM":"2021-02-17 08:54:24","AP02SDTM":"2021-02-17 08:54:24","AP02EDTM":"2022-02-17 14:54:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1045,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-15","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":255,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.65525,"AVALU":"mg/L","BASE2":9.8709,"BASE":7.38324,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.78434,"PCHG2":7.946,"CHG":3.27201,"PCHG":44.31673,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"2","BTOXGR":"-3","ADTM":"2020-12-11 23:09:23","ADY":612,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-227","SUBJID":"id-227","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.1904,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-07","TRTSDTM":"2019-04-09 23:09:23","TRTEDTM":"2022-02-17 14:54:24","TRT01SDTM":"2019-04-09 23:09:23","TRT01EDTM":"2021-02-17 08:54:24","TRT02SDTM":"2021-02-17 08:54:24","TRT02EDTM":"2022-02-17 14:54:24","AP01SDTM":"2019-04-09 23:09:23","AP01EDTM":"2021-02-17 08:54:24","AP02SDTM":"2021-02-17 08:54:24","AP02EDTM":"2022-02-17 14:54:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1045,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-15","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1600,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.87929,"AVALU":"mg/L","BASE2":9.8709,"BASE":7.38324,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.99162,"PCHG2":-10.04588,"CHG":1.49605,"PCHG":20.26277,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-06-12 23:09:23","ADY":795,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-227","SUBJID":"id-227","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.1904,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-07","TRTSDTM":"2019-04-09 23:09:23","TRTEDTM":"2022-02-17 14:54:24","TRT01SDTM":"2019-04-09 23:09:23","TRT01EDTM":"2021-02-17 08:54:24","TRT02SDTM":"2021-02-17 08:54:24","TRT02EDTM":"2022-02-17 14:54:24","AP01SDTM":"2019-04-09 23:09:23","AP01EDTM":"2021-02-17 08:54:24","AP02SDTM":"2021-02-17 08:54:24","AP02EDTM":"2022-02-17 14:54:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1045,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-15","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8318,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.58071,"AVALU":"mg/L","BASE2":9.8709,"BASE":7.38324,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.2902,"PCHG2":-13.07071,"CHG":1.19747,"PCHG":16.21876,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-10-29 23:09:23","ADY":934,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-227","SUBJID":"id-227","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.1904,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-07","TRTSDTM":"2019-04-09 23:09:23","TRTEDTM":"2022-02-17 14:54:24","TRT01SDTM":"2019-04-09 23:09:23","TRT01EDTM":"2021-02-17 08:54:24","TRT02SDTM":"2021-02-17 08:54:24","TRT02EDTM":"2022-02-17 14:54:24","AP01SDTM":"2019-04-09 23:09:23","AP01EDTM":"2021-02-17 08:54:24","AP02SDTM":"2021-02-17 08:54:24","AP02EDTM":"2022-02-17 14:54:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1045,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-15","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1171,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00398,"AVALU":"g/L","BASE2":3.00398,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"3","BTOXGR":"0","ADTM":"2019-12-29 23:09:23","ADY":264,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-227","SUBJID":"id-227","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.1904,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-07","TRTSDTM":"2019-04-09 23:09:23","TRTEDTM":"2022-02-17 14:54:24","TRT01SDTM":"2019-04-09 23:09:23","TRT01EDTM":"2021-02-17 08:54:24","TRT02SDTM":"2021-02-17 08:54:24","TRT02EDTM":"2022-02-17 14:54:24","AP01SDTM":"2019-04-09 23:09:23","AP01EDTM":"2021-02-17 08:54:24","AP02SDTM":"2021-02-17 08:54:24","AP02EDTM":"2022-02-17 14:54:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1045,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-15","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3169,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95588,"AVALU":"g/L","BASE2":3.00398,"BASE":2.95588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.0481,"PCHG2":-1.60106,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-20 23:09:23","ADY":286,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-227","SUBJID":"id-227","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.1904,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-07","TRTSDTM":"2019-04-09 23:09:23","TRTEDTM":"2022-02-17 14:54:24","TRT01SDTM":"2019-04-09 23:09:23","TRT01EDTM":"2021-02-17 08:54:24","TRT02SDTM":"2021-02-17 08:54:24","TRT02EDTM":"2022-02-17 14:54:24","AP01SDTM":"2019-04-09 23:09:23","AP01EDTM":"2021-02-17 08:54:24","AP02SDTM":"2021-02-17 08:54:24","AP02EDTM":"2022-02-17 14:54:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1045,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-15","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1141,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82143,"AVALU":"g/L","BASE2":3.00398,"BASE":2.95588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18255,"PCHG2":-6.07691,"CHG":-0.13445,"PCHG":-4.54868,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-16 23:09:23","ADY":403,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-227","SUBJID":"id-227","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.1904,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-07","TRTSDTM":"2019-04-09 23:09:23","TRTEDTM":"2022-02-17 14:54:24","TRT01SDTM":"2019-04-09 23:09:23","TRT01EDTM":"2021-02-17 08:54:24","TRT02SDTM":"2021-02-17 08:54:24","TRT02EDTM":"2022-02-17 14:54:24","AP01SDTM":"2019-04-09 23:09:23","AP01EDTM":"2021-02-17 08:54:24","AP02SDTM":"2021-02-17 08:54:24","AP02EDTM":"2022-02-17 14:54:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1045,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-15","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6026,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90048,"AVALU":"g/L","BASE2":3.00398,"BASE":2.95588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1035,"PCHG2":-3.44541,"CHG":-0.0554,"PCHG":-1.87436,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-07 23:09:23","ADY":608,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-227","SUBJID":"id-227","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.1904,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-07","TRTSDTM":"2019-04-09 23:09:23","TRTEDTM":"2022-02-17 14:54:24","TRT01SDTM":"2019-04-09 23:09:23","TRT01EDTM":"2021-02-17 08:54:24","TRT02SDTM":"2021-02-17 08:54:24","TRT02EDTM":"2022-02-17 14:54:24","AP01SDTM":"2019-04-09 23:09:23","AP01EDTM":"2021-02-17 08:54:24","AP02SDTM":"2021-02-17 08:54:24","AP02EDTM":"2022-02-17 14:54:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1045,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-15","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8182,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79557,"AVALU":"g/L","BASE2":3.00398,"BASE":2.95588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20841,"PCHG2":-6.93774,"CHG":-0.16031,"PCHG":-5.42352,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-11 23:09:23","ADY":612,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-227","SUBJID":"id-227","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.1904,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-07","TRTSDTM":"2019-04-09 23:09:23","TRTEDTM":"2022-02-17 14:54:24","TRT01SDTM":"2019-04-09 23:09:23","TRT01EDTM":"2021-02-17 08:54:24","TRT02SDTM":"2021-02-17 08:54:24","TRT02EDTM":"2022-02-17 14:54:24","AP01SDTM":"2019-04-09 23:09:23","AP01EDTM":"2021-02-17 08:54:24","AP02SDTM":"2021-02-17 08:54:24","AP02EDTM":"2022-02-17 14:54:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1045,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-15","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7570,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88007,"AVALU":"g/L","BASE2":3.00398,"BASE":2.95588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12391,"PCHG2":-4.12491,"CHG":-0.07582,"PCHG":-2.56492,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-12 23:09:23","ADY":795,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-227","SUBJID":"id-227","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.1904,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-07","TRTSDTM":"2019-04-09 23:09:23","TRTEDTM":"2022-02-17 14:54:24","TRT01SDTM":"2019-04-09 23:09:23","TRT01EDTM":"2021-02-17 08:54:24","TRT02SDTM":"2021-02-17 08:54:24","TRT02EDTM":"2022-02-17 14:54:24","AP01SDTM":"2019-04-09 23:09:23","AP01EDTM":"2021-02-17 08:54:24","AP02SDTM":"2021-02-17 08:54:24","AP02EDTM":"2022-02-17 14:54:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1045,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-15","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5151,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93587,"AVALU":"g/L","BASE2":3.00398,"BASE":2.95588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06811,"PCHG2":-2.26732,"CHG":-0.02001,"PCHG":-0.67711,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-29 23:09:23","ADY":934,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-229","SUBJID":"id-229","SITEID":"CHN-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":9.50695,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 12:03:40","TRTEDTM":"2022-02-19 20:39:33","TRT01SDTM":"2020-10-13 12:03:40","TRT01EDTM":"2021-02-19 14:39:33","TRT02SDTM":"2021-02-19 14:39:33","TRT02EDTM":"2022-02-19 20:39:33","AP01SDTM":"2020-10-13 12:03:40","AP01EDTM":"2021-02-19 14:39:33","AP02SDTM":"2021-02-19 14:39:33","AP02EDTM":"2022-02-19 20:39:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":495,"DCSREAS":"DEATH","DTHDT":"2022-04-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-10","DTHADY":543,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6840,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.79231,"AVALU":"U/L","BASE2":24.79231,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-06 12:03:40","ADY":24,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-229","SUBJID":"id-229","SITEID":"CHN-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":9.50695,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 12:03:40","TRTEDTM":"2022-02-19 20:39:33","TRT01SDTM":"2020-10-13 12:03:40","TRT01EDTM":"2021-02-19 14:39:33","TRT02SDTM":"2021-02-19 14:39:33","TRT02EDTM":"2022-02-19 20:39:33","AP01SDTM":"2020-10-13 12:03:40","AP01EDTM":"2021-02-19 14:39:33","AP02SDTM":"2021-02-19 14:39:33","AP02EDTM":"2022-02-19 20:39:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":495,"DCSREAS":"DEATH","DTHDT":"2022-04-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-10","DTHADY":543,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7098,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":37.26341,"AVALU":"U/L","BASE2":24.79231,"BASE":37.26341,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":12.4711,"PCHG2":50.30229,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-15 12:03:40","ADY":125,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-229","SUBJID":"id-229","SITEID":"CHN-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":9.50695,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 12:03:40","TRTEDTM":"2022-02-19 20:39:33","TRT01SDTM":"2020-10-13 12:03:40","TRT01EDTM":"2021-02-19 14:39:33","TRT02SDTM":"2021-02-19 14:39:33","TRT02EDTM":"2022-02-19 20:39:33","AP01SDTM":"2020-10-13 12:03:40","AP01EDTM":"2021-02-19 14:39:33","AP02SDTM":"2021-02-19 14:39:33","AP02EDTM":"2022-02-19 20:39:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":495,"DCSREAS":"DEATH","DTHDT":"2022-04-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-10","DTHADY":543,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3028,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.53906,"AVALU":"U/L","BASE2":24.79231,"BASE":37.26341,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-18.25324,"PCHG2":-73.62462,"CHG":-30.72434,"PCHG":-82.45178,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-06-11 12:03:40","ADY":241,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-229","SUBJID":"id-229","SITEID":"CHN-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":9.50695,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 12:03:40","TRTEDTM":"2022-02-19 20:39:33","TRT01SDTM":"2020-10-13 12:03:40","TRT01EDTM":"2021-02-19 14:39:33","TRT02SDTM":"2021-02-19 14:39:33","TRT02EDTM":"2022-02-19 20:39:33","AP01SDTM":"2020-10-13 12:03:40","AP01EDTM":"2021-02-19 14:39:33","AP02SDTM":"2021-02-19 14:39:33","AP02EDTM":"2022-02-19 20:39:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":495,"DCSREAS":"DEATH","DTHDT":"2022-04-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-10","DTHADY":543,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1160,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.08258,"AVALU":"U/L","BASE2":24.79231,"BASE":37.26341,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.70973,"PCHG2":-31.09727,"CHG":-20.18083,"PCHG":-54.15723,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-29 12:03:40","ADY":381,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-229","SUBJID":"id-229","SITEID":"CHN-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":9.50695,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 12:03:40","TRTEDTM":"2022-02-19 20:39:33","TRT01SDTM":"2020-10-13 12:03:40","TRT01EDTM":"2021-02-19 14:39:33","TRT02SDTM":"2021-02-19 14:39:33","TRT02EDTM":"2022-02-19 20:39:33","AP01SDTM":"2020-10-13 12:03:40","AP01EDTM":"2021-02-19 14:39:33","AP02SDTM":"2021-02-19 14:39:33","AP02EDTM":"2022-02-19 20:39:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":495,"DCSREAS":"DEATH","DTHDT":"2022-04-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-10","DTHADY":543,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1293,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.22757,"AVALU":"U/L","BASE2":24.79231,"BASE":37.26341,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.56474,"PCHG2":-10.3449,"CHG":-15.03584,"PCHG":-40.35014,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-11 12:03:40","ADY":394,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-229","SUBJID":"id-229","SITEID":"CHN-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":9.50695,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 12:03:40","TRTEDTM":"2022-02-19 20:39:33","TRT01SDTM":"2020-10-13 12:03:40","TRT01EDTM":"2021-02-19 14:39:33","TRT02SDTM":"2021-02-19 14:39:33","TRT02EDTM":"2022-02-19 20:39:33","AP01SDTM":"2020-10-13 12:03:40","AP01EDTM":"2021-02-19 14:39:33","AP02SDTM":"2021-02-19 14:39:33","AP02EDTM":"2022-02-19 20:39:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":495,"DCSREAS":"DEATH","DTHDT":"2022-04-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-10","DTHADY":543,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7248,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.90227,"AVALU":"U/L","BASE2":24.79231,"BASE":37.26341,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-21.89004,"PCHG2":-88.29367,"CHG":-34.36114,"PCHG":-92.21147,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-12-19 12:03:40","ADY":432,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-229","SUBJID":"id-229","SITEID":"CHN-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":9.50695,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 12:03:40","TRTEDTM":"2022-02-19 20:39:33","TRT01SDTM":"2020-10-13 12:03:40","TRT01EDTM":"2021-02-19 14:39:33","TRT02SDTM":"2021-02-19 14:39:33","TRT02EDTM":"2022-02-19 20:39:33","AP01SDTM":"2020-10-13 12:03:40","AP01EDTM":"2021-02-19 14:39:33","AP02SDTM":"2021-02-19 14:39:33","AP02EDTM":"2022-02-19 20:39:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":495,"DCSREAS":"DEATH","DTHDT":"2022-04-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-10","DTHADY":543,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":210,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.40267,"AVALU":"U/L","BASE2":24.79231,"BASE":37.26341,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.61036,"PCHG2":18.59594,"CHG":-7.86074,"PCHG":-21.09505,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-17 12:03:40","ADY":492,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-229","SUBJID":"id-229","SITEID":"CHN-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":9.50695,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 12:03:40","TRTEDTM":"2022-02-19 20:39:33","TRT01SDTM":"2020-10-13 12:03:40","TRT01EDTM":"2021-02-19 14:39:33","TRT02SDTM":"2021-02-19 14:39:33","TRT02EDTM":"2022-02-19 20:39:33","AP01SDTM":"2020-10-13 12:03:40","AP01EDTM":"2021-02-19 14:39:33","AP02SDTM":"2021-02-19 14:39:33","AP02EDTM":"2022-02-19 20:39:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":495,"DCSREAS":"DEATH","DTHDT":"2022-04-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-10","DTHADY":543,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2563,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.07144,"AVALU":"mg/L","BASE2":9.07144,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-06 12:03:40","ADY":24,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-229","SUBJID":"id-229","SITEID":"CHN-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":9.50695,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 12:03:40","TRTEDTM":"2022-02-19 20:39:33","TRT01SDTM":"2020-10-13 12:03:40","TRT01EDTM":"2021-02-19 14:39:33","TRT02SDTM":"2021-02-19 14:39:33","TRT02EDTM":"2022-02-19 20:39:33","AP01SDTM":"2020-10-13 12:03:40","AP01EDTM":"2021-02-19 14:39:33","AP02SDTM":"2021-02-19 14:39:33","AP02EDTM":"2022-02-19 20:39:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":495,"DCSREAS":"DEATH","DTHDT":"2022-04-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-10","DTHADY":543,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7244,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.18073,"AVALU":"mg/L","BASE2":9.07144,"BASE":9.18073,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.1093,"PCHG2":1.20483,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-15 12:03:40","ADY":125,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-229","SUBJID":"id-229","SITEID":"CHN-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":9.50695,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 12:03:40","TRTEDTM":"2022-02-19 20:39:33","TRT01SDTM":"2020-10-13 12:03:40","TRT01EDTM":"2021-02-19 14:39:33","TRT02SDTM":"2021-02-19 14:39:33","TRT02EDTM":"2022-02-19 20:39:33","AP01SDTM":"2020-10-13 12:03:40","AP01EDTM":"2021-02-19 14:39:33","AP02SDTM":"2021-02-19 14:39:33","AP02EDTM":"2022-02-19 20:39:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":495,"DCSREAS":"DEATH","DTHDT":"2022-04-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-10","DTHADY":543,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8357,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.67462,"AVALU":"mg/L","BASE2":9.07144,"BASE":9.18073,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.39682,"PCHG2":-4.37435,"CHG":-0.50611,"PCHG":-5.51276,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-11 12:03:40","ADY":241,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-229","SUBJID":"id-229","SITEID":"CHN-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":9.50695,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 12:03:40","TRTEDTM":"2022-02-19 20:39:33","TRT01SDTM":"2020-10-13 12:03:40","TRT01EDTM":"2021-02-19 14:39:33","TRT02SDTM":"2021-02-19 14:39:33","TRT02EDTM":"2022-02-19 20:39:33","AP01SDTM":"2020-10-13 12:03:40","AP01EDTM":"2021-02-19 14:39:33","AP02SDTM":"2021-02-19 14:39:33","AP02EDTM":"2022-02-19 20:39:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":495,"DCSREAS":"DEATH","DTHDT":"2022-04-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-10","DTHADY":543,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6779,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.19222,"AVALU":"mg/L","BASE2":9.07144,"BASE":9.18073,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.12078,"PCHG2":12.35501,"CHG":1.01148,"PCHG":11.01744,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-10-29 12:03:40","ADY":381,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-229","SUBJID":"id-229","SITEID":"CHN-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":9.50695,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 12:03:40","TRTEDTM":"2022-02-19 20:39:33","TRT01SDTM":"2020-10-13 12:03:40","TRT01EDTM":"2021-02-19 14:39:33","TRT02SDTM":"2021-02-19 14:39:33","TRT02EDTM":"2022-02-19 20:39:33","AP01SDTM":"2020-10-13 12:03:40","AP01EDTM":"2021-02-19 14:39:33","AP02SDTM":"2021-02-19 14:39:33","AP02EDTM":"2022-02-19 20:39:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":495,"DCSREAS":"DEATH","DTHDT":"2022-04-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-10","DTHADY":543,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7951,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.92355,"AVALU":"mg/L","BASE2":9.07144,"BASE":9.18073,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.85211,"PCHG2":9.39335,"CHG":0.74282,"PCHG":8.09104,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-11 12:03:40","ADY":394,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-229","SUBJID":"id-229","SITEID":"CHN-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":9.50695,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 12:03:40","TRTEDTM":"2022-02-19 20:39:33","TRT01SDTM":"2020-10-13 12:03:40","TRT01EDTM":"2021-02-19 14:39:33","TRT02SDTM":"2021-02-19 14:39:33","TRT02EDTM":"2022-02-19 20:39:33","AP01SDTM":"2020-10-13 12:03:40","AP01EDTM":"2021-02-19 14:39:33","AP02SDTM":"2021-02-19 14:39:33","AP02EDTM":"2022-02-19 20:39:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":495,"DCSREAS":"DEATH","DTHDT":"2022-04-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-10","DTHADY":543,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7035,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.92903,"AVALU":"mg/L","BASE2":9.07144,"BASE":9.18073,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.14241,"PCHG2":-12.59343,"CHG":-1.2517,"PCHG":-13.63399,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-12-19 12:03:40","ADY":432,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-229","SUBJID":"id-229","SITEID":"CHN-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":9.50695,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 12:03:40","TRTEDTM":"2022-02-19 20:39:33","TRT01SDTM":"2020-10-13 12:03:40","TRT01EDTM":"2021-02-19 14:39:33","TRT02SDTM":"2021-02-19 14:39:33","TRT02EDTM":"2022-02-19 20:39:33","AP01SDTM":"2020-10-13 12:03:40","AP01EDTM":"2021-02-19 14:39:33","AP02SDTM":"2021-02-19 14:39:33","AP02EDTM":"2022-02-19 20:39:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":495,"DCSREAS":"DEATH","DTHDT":"2022-04-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-10","DTHADY":543,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3609,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.71845,"AVALU":"mg/L","BASE2":9.07144,"BASE":9.18073,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.64701,"PCHG2":7.13234,"CHG":0.53771,"PCHG":5.85695,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-17 12:03:40","ADY":492,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-229","SUBJID":"id-229","SITEID":"CHN-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":9.50695,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 12:03:40","TRTEDTM":"2022-02-19 20:39:33","TRT01SDTM":"2020-10-13 12:03:40","TRT01EDTM":"2021-02-19 14:39:33","TRT02SDTM":"2021-02-19 14:39:33","TRT02EDTM":"2022-02-19 20:39:33","AP01SDTM":"2020-10-13 12:03:40","AP01EDTM":"2021-02-19 14:39:33","AP02SDTM":"2021-02-19 14:39:33","AP02EDTM":"2022-02-19 20:39:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":495,"DCSREAS":"DEATH","DTHDT":"2022-04-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-10","DTHADY":543,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3722,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98141,"AVALU":"g/L","BASE2":2.98141,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"2","ADTM":"2020-11-06 12:03:40","ADY":24,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-229","SUBJID":"id-229","SITEID":"CHN-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":9.50695,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 12:03:40","TRTEDTM":"2022-02-19 20:39:33","TRT01SDTM":"2020-10-13 12:03:40","TRT01EDTM":"2021-02-19 14:39:33","TRT02SDTM":"2021-02-19 14:39:33","TRT02EDTM":"2022-02-19 20:39:33","AP01SDTM":"2020-10-13 12:03:40","AP01EDTM":"2021-02-19 14:39:33","AP02SDTM":"2021-02-19 14:39:33","AP02EDTM":"2022-02-19 20:39:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":495,"DCSREAS":"DEATH","DTHDT":"2022-04-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-10","DTHADY":543,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4281,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03817,"AVALU":"g/L","BASE2":2.98141,"BASE":3.03817,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.05676,"PCHG2":1.90364,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2021-02-15 12:03:40","ADY":125,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-229","SUBJID":"id-229","SITEID":"CHN-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":9.50695,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 12:03:40","TRTEDTM":"2022-02-19 20:39:33","TRT01SDTM":"2020-10-13 12:03:40","TRT01EDTM":"2021-02-19 14:39:33","TRT02SDTM":"2021-02-19 14:39:33","TRT02EDTM":"2022-02-19 20:39:33","AP01SDTM":"2020-10-13 12:03:40","AP01EDTM":"2021-02-19 14:39:33","AP02SDTM":"2021-02-19 14:39:33","AP02EDTM":"2022-02-19 20:39:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":495,"DCSREAS":"DEATH","DTHDT":"2022-04-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-10","DTHADY":543,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2618,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83825,"AVALU":"g/L","BASE2":2.98141,"BASE":3.03817,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14316,"PCHG2":-4.80168,"CHG":-0.19991,"PCHG":-6.58006,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-06-11 12:03:40","ADY":241,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-229","SUBJID":"id-229","SITEID":"CHN-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":9.50695,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 12:03:40","TRTEDTM":"2022-02-19 20:39:33","TRT01SDTM":"2020-10-13 12:03:40","TRT01EDTM":"2021-02-19 14:39:33","TRT02SDTM":"2021-02-19 14:39:33","TRT02EDTM":"2022-02-19 20:39:33","AP01SDTM":"2020-10-13 12:03:40","AP01EDTM":"2021-02-19 14:39:33","AP02SDTM":"2021-02-19 14:39:33","AP02EDTM":"2022-02-19 20:39:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":495,"DCSREAS":"DEATH","DTHDT":"2022-04-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-10","DTHADY":543,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7085,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81732,"AVALU":"g/L","BASE2":2.98141,"BASE":3.03817,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16409,"PCHG2":-5.50374,"CHG":-0.22084,"PCHG":-7.269,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-10-29 12:03:40","ADY":381,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-229","SUBJID":"id-229","SITEID":"CHN-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":9.50695,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 12:03:40","TRTEDTM":"2022-02-19 20:39:33","TRT01SDTM":"2020-10-13 12:03:40","TRT01EDTM":"2021-02-19 14:39:33","TRT02SDTM":"2021-02-19 14:39:33","TRT02EDTM":"2022-02-19 20:39:33","AP01SDTM":"2020-10-13 12:03:40","AP01EDTM":"2021-02-19 14:39:33","AP02SDTM":"2021-02-19 14:39:33","AP02EDTM":"2022-02-19 20:39:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":495,"DCSREAS":"DEATH","DTHDT":"2022-04-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-10","DTHADY":543,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3151,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93667,"AVALU":"g/L","BASE2":2.98141,"BASE":3.03817,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04474,"PCHG2":-1.50061,"CHG":-0.10149,"PCHG":-3.34065,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-11-11 12:03:40","ADY":394,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-229","SUBJID":"id-229","SITEID":"CHN-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":9.50695,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 12:03:40","TRTEDTM":"2022-02-19 20:39:33","TRT01SDTM":"2020-10-13 12:03:40","TRT01EDTM":"2021-02-19 14:39:33","TRT02SDTM":"2021-02-19 14:39:33","TRT02EDTM":"2022-02-19 20:39:33","AP01SDTM":"2020-10-13 12:03:40","AP01EDTM":"2021-02-19 14:39:33","AP02SDTM":"2021-02-19 14:39:33","AP02EDTM":"2022-02-19 20:39:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":495,"DCSREAS":"DEATH","DTHDT":"2022-04-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-10","DTHADY":543,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":564,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97034,"AVALU":"g/L","BASE2":2.98141,"BASE":3.03817,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01107,"PCHG2":-0.37133,"CHG":-0.06783,"PCHG":-2.23247,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-12-19 12:03:40","ADY":432,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-229","SUBJID":"id-229","SITEID":"CHN-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":9.50695,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 12:03:40","TRTEDTM":"2022-02-19 20:39:33","TRT01SDTM":"2020-10-13 12:03:40","TRT01EDTM":"2021-02-19 14:39:33","TRT02SDTM":"2021-02-19 14:39:33","TRT02EDTM":"2022-02-19 20:39:33","AP01SDTM":"2020-10-13 12:03:40","AP01EDTM":"2021-02-19 14:39:33","AP02SDTM":"2021-02-19 14:39:33","AP02EDTM":"2022-02-19 20:39:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":495,"DCSREAS":"DEATH","DTHDT":"2022-04-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-10","DTHADY":543,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4900,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74224,"AVALU":"g/L","BASE2":2.98141,"BASE":3.03817,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.23917,"PCHG2":-8.02215,"CHG":-0.29593,"PCHG":-9.74037,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-02-17 12:03:40","ADY":492,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-232","SUBJID":"id-232","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.17424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-24 14:35:03","TRTEDTM":"2023-02-24 08:35:03","TRT01SDTM":"2020-02-24 14:35:03","TRT01EDTM":"2022-02-24 02:35:03","TRT02SDTM":"2022-02-24 02:35:03","TRT02EDTM":"2023-02-24 08:35:03","AP01SDTM":"2020-02-24 14:35:03","AP01EDTM":"2022-02-24 02:35:03","AP02SDTM":"2022-02-24 02:35:03","AP02EDTM":"2023-02-24 08:35:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-24","EOSDY":1096,"LSTALVDT":"2023-03-16","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3067,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.69092,"AVALU":"U/L","BASE2":14.69092,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-29 14:35:03","ADY":126,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-232","SUBJID":"id-232","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.17424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-24 14:35:03","TRTEDTM":"2023-02-24 08:35:03","TRT01SDTM":"2020-02-24 14:35:03","TRT01EDTM":"2022-02-24 02:35:03","TRT02SDTM":"2022-02-24 02:35:03","TRT02EDTM":"2023-02-24 08:35:03","AP01SDTM":"2020-02-24 14:35:03","AP01EDTM":"2022-02-24 02:35:03","AP02SDTM":"2022-02-24 02:35:03","AP02EDTM":"2023-02-24 08:35:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-24","EOSDY":1096,"LSTALVDT":"2023-03-16","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7818,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.32701,"AVALU":"U/L","BASE2":14.69092,"BASE":10.32701,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-4.36391,"PCHG2":-29.70481,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-09 14:35:03","ADY":532,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-232","SUBJID":"id-232","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.17424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-24 14:35:03","TRTEDTM":"2023-02-24 08:35:03","TRT01SDTM":"2020-02-24 14:35:03","TRT01EDTM":"2022-02-24 02:35:03","TRT02SDTM":"2022-02-24 02:35:03","TRT02EDTM":"2023-02-24 08:35:03","AP01SDTM":"2020-02-24 14:35:03","AP01EDTM":"2022-02-24 02:35:03","AP02SDTM":"2022-02-24 02:35:03","AP02EDTM":"2023-02-24 08:35:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-24","EOSDY":1096,"LSTALVDT":"2023-03-16","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2830,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.32801,"AVALU":"U/L","BASE2":14.69092,"BASE":10.32701,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.63709,"PCHG2":24.75738,"CHG":8.001,"PCHG":77.4764,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-07 14:35:03","ADY":622,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-232","SUBJID":"id-232","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.17424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-24 14:35:03","TRTEDTM":"2023-02-24 08:35:03","TRT01SDTM":"2020-02-24 14:35:03","TRT01EDTM":"2022-02-24 02:35:03","TRT02SDTM":"2022-02-24 02:35:03","TRT02EDTM":"2023-02-24 08:35:03","AP01SDTM":"2020-02-24 14:35:03","AP01EDTM":"2022-02-24 02:35:03","AP02SDTM":"2022-02-24 02:35:03","AP02EDTM":"2023-02-24 08:35:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-24","EOSDY":1096,"LSTALVDT":"2023-03-16","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7010,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.03948,"AVALU":"U/L","BASE2":14.69092,"BASE":10.32701,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.34856,"PCHG2":29.6003,"CHG":8.71247,"PCHG":84.3658,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-27 14:35:03","ADY":672,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-232","SUBJID":"id-232","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.17424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-24 14:35:03","TRTEDTM":"2023-02-24 08:35:03","TRT01SDTM":"2020-02-24 14:35:03","TRT01EDTM":"2022-02-24 02:35:03","TRT02SDTM":"2022-02-24 02:35:03","TRT02EDTM":"2023-02-24 08:35:03","AP01SDTM":"2020-02-24 14:35:03","AP01EDTM":"2022-02-24 02:35:03","AP02SDTM":"2022-02-24 02:35:03","AP02EDTM":"2023-02-24 08:35:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-24","EOSDY":1096,"LSTALVDT":"2023-03-16","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1799,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.79781,"AVALU":"U/L","BASE2":14.69092,"BASE":10.32701,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.10689,"PCHG2":102.83146,"CHG":19.4708,"PCHG":188.54243,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-19 14:35:03","ADY":726,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-232","SUBJID":"id-232","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.17424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-24 14:35:03","TRTEDTM":"2023-02-24 08:35:03","TRT01SDTM":"2020-02-24 14:35:03","TRT01EDTM":"2022-02-24 02:35:03","TRT02SDTM":"2022-02-24 02:35:03","TRT02EDTM":"2023-02-24 08:35:03","AP01SDTM":"2020-02-24 14:35:03","AP01EDTM":"2022-02-24 02:35:03","AP02SDTM":"2022-02-24 02:35:03","AP02EDTM":"2023-02-24 08:35:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-24","EOSDY":1096,"LSTALVDT":"2023-03-16","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8051,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.37639,"AVALU":"U/L","BASE2":14.69092,"BASE":10.32701,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.68547,"PCHG2":45.5075,"CHG":11.04938,"PCHG":106.99495,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-21 14:35:03","ADY":817,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-232","SUBJID":"id-232","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.17424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-24 14:35:03","TRTEDTM":"2023-02-24 08:35:03","TRT01SDTM":"2020-02-24 14:35:03","TRT01EDTM":"2022-02-24 02:35:03","TRT02SDTM":"2022-02-24 02:35:03","TRT02EDTM":"2023-02-24 08:35:03","AP01SDTM":"2020-02-24 14:35:03","AP01EDTM":"2022-02-24 02:35:03","AP02SDTM":"2022-02-24 02:35:03","AP02EDTM":"2023-02-24 08:35:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-24","EOSDY":1096,"LSTALVDT":"2023-03-16","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3908,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.84277,"AVALU":"U/L","BASE2":14.69092,"BASE":10.32701,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.84815,"PCHG2":-87.4564,"CHG":-8.48424,"PCHG":-82.15582,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-08-13 14:35:03","ADY":901,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-232","SUBJID":"id-232","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.17424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-24 14:35:03","TRTEDTM":"2023-02-24 08:35:03","TRT01SDTM":"2020-02-24 14:35:03","TRT01EDTM":"2022-02-24 02:35:03","TRT02SDTM":"2022-02-24 02:35:03","TRT02EDTM":"2023-02-24 08:35:03","AP01SDTM":"2020-02-24 14:35:03","AP01EDTM":"2022-02-24 02:35:03","AP02SDTM":"2022-02-24 02:35:03","AP02EDTM":"2023-02-24 08:35:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-24","EOSDY":1096,"LSTALVDT":"2023-03-16","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7268,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.70135,"AVALU":"mg/L","BASE2":9.70135,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-29 14:35:03","ADY":126,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-232","SUBJID":"id-232","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.17424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-24 14:35:03","TRTEDTM":"2023-02-24 08:35:03","TRT01SDTM":"2020-02-24 14:35:03","TRT01EDTM":"2022-02-24 02:35:03","TRT02SDTM":"2022-02-24 02:35:03","TRT02EDTM":"2023-02-24 08:35:03","AP01SDTM":"2020-02-24 14:35:03","AP01EDTM":"2022-02-24 02:35:03","AP02SDTM":"2022-02-24 02:35:03","AP02EDTM":"2023-02-24 08:35:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-24","EOSDY":1096,"LSTALVDT":"2023-03-16","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3768,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.83251,"AVALU":"mg/L","BASE2":9.70135,"BASE":8.83251,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.86884,"PCHG2":-8.95585,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-09 14:35:03","ADY":532,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-232","SUBJID":"id-232","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.17424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-24 14:35:03","TRTEDTM":"2023-02-24 08:35:03","TRT01SDTM":"2020-02-24 14:35:03","TRT01EDTM":"2022-02-24 02:35:03","TRT02SDTM":"2022-02-24 02:35:03","TRT02EDTM":"2023-02-24 08:35:03","AP01SDTM":"2020-02-24 14:35:03","AP01EDTM":"2022-02-24 02:35:03","AP02SDTM":"2022-02-24 02:35:03","AP02EDTM":"2023-02-24 08:35:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-24","EOSDY":1096,"LSTALVDT":"2023-03-16","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1241,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.32767,"AVALU":"mg/L","BASE2":9.70135,"BASE":8.83251,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.37368,"PCHG2":-14.15968,"CHG":-0.50484,"PCHG":-5.71572,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-07 14:35:03","ADY":622,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-232","SUBJID":"id-232","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.17424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-24 14:35:03","TRTEDTM":"2023-02-24 08:35:03","TRT01SDTM":"2020-02-24 14:35:03","TRT01EDTM":"2022-02-24 02:35:03","TRT02SDTM":"2022-02-24 02:35:03","TRT02EDTM":"2023-02-24 08:35:03","AP01SDTM":"2020-02-24 14:35:03","AP01EDTM":"2022-02-24 02:35:03","AP02SDTM":"2022-02-24 02:35:03","AP02EDTM":"2023-02-24 08:35:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-24","EOSDY":1096,"LSTALVDT":"2023-03-16","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6885,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.33105,"AVALU":"mg/L","BASE2":9.70135,"BASE":8.83251,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.6297,"PCHG2":16.79866,"CHG":2.49854,"PCHG":28.28793,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-12-27 14:35:03","ADY":672,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-232","SUBJID":"id-232","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.17424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-24 14:35:03","TRTEDTM":"2023-02-24 08:35:03","TRT01SDTM":"2020-02-24 14:35:03","TRT01EDTM":"2022-02-24 02:35:03","TRT02SDTM":"2022-02-24 02:35:03","TRT02EDTM":"2023-02-24 08:35:03","AP01SDTM":"2020-02-24 14:35:03","AP01EDTM":"2022-02-24 02:35:03","AP02SDTM":"2022-02-24 02:35:03","AP02EDTM":"2023-02-24 08:35:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-24","EOSDY":1096,"LSTALVDT":"2023-03-16","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3662,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.04591,"AVALU":"mg/L","BASE2":9.70135,"BASE":8.83251,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.65544,"PCHG2":-17.06399,"CHG":-0.7866,"PCHG":-8.90573,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-19 14:35:03","ADY":726,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-232","SUBJID":"id-232","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.17424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-24 14:35:03","TRTEDTM":"2023-02-24 08:35:03","TRT01SDTM":"2020-02-24 14:35:03","TRT01EDTM":"2022-02-24 02:35:03","TRT02SDTM":"2022-02-24 02:35:03","TRT02EDTM":"2023-02-24 08:35:03","AP01SDTM":"2020-02-24 14:35:03","AP01EDTM":"2022-02-24 02:35:03","AP02SDTM":"2022-02-24 02:35:03","AP02EDTM":"2023-02-24 08:35:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-24","EOSDY":1096,"LSTALVDT":"2023-03-16","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4301,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.31573,"AVALU":"mg/L","BASE2":9.70135,"BASE":8.83251,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.38562,"PCHG2":-14.28279,"CHG":-0.51679,"PCHG":-5.85095,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-21 14:35:03","ADY":817,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-232","SUBJID":"id-232","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.17424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-24 14:35:03","TRTEDTM":"2023-02-24 08:35:03","TRT01SDTM":"2020-02-24 14:35:03","TRT01EDTM":"2022-02-24 02:35:03","TRT02SDTM":"2022-02-24 02:35:03","TRT02EDTM":"2023-02-24 08:35:03","AP01SDTM":"2020-02-24 14:35:03","AP01EDTM":"2022-02-24 02:35:03","AP02SDTM":"2022-02-24 02:35:03","AP02EDTM":"2023-02-24 08:35:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-24","EOSDY":1096,"LSTALVDT":"2023-03-16","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7778,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.66236,"AVALU":"mg/L","BASE2":9.70135,"BASE":8.83251,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03899,"PCHG2":-0.40189,"CHG":0.82985,"PCHG":9.39539,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-13 14:35:03","ADY":901,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-232","SUBJID":"id-232","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.17424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-24 14:35:03","TRTEDTM":"2023-02-24 08:35:03","TRT01SDTM":"2020-02-24 14:35:03","TRT01EDTM":"2022-02-24 02:35:03","TRT02SDTM":"2022-02-24 02:35:03","TRT02EDTM":"2023-02-24 08:35:03","AP01SDTM":"2020-02-24 14:35:03","AP01EDTM":"2022-02-24 02:35:03","AP02SDTM":"2022-02-24 02:35:03","AP02EDTM":"2023-02-24 08:35:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-24","EOSDY":1096,"LSTALVDT":"2023-03-16","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":785,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01817,"AVALU":"g/L","BASE2":3.01817,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-06-29 14:35:03","ADY":126,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-232","SUBJID":"id-232","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.17424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-24 14:35:03","TRTEDTM":"2023-02-24 08:35:03","TRT01SDTM":"2020-02-24 14:35:03","TRT01EDTM":"2022-02-24 02:35:03","TRT02SDTM":"2022-02-24 02:35:03","TRT02EDTM":"2023-02-24 08:35:03","AP01SDTM":"2020-02-24 14:35:03","AP01EDTM":"2022-02-24 02:35:03","AP02SDTM":"2022-02-24 02:35:03","AP02EDTM":"2023-02-24 08:35:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-24","EOSDY":1096,"LSTALVDT":"2023-03-16","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98977,"AVALU":"g/L","BASE2":3.01817,"BASE":2.98977,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.02841,"PCHG2":-0.94116,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-09 14:35:03","ADY":532,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-232","SUBJID":"id-232","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.17424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-24 14:35:03","TRTEDTM":"2023-02-24 08:35:03","TRT01SDTM":"2020-02-24 14:35:03","TRT01EDTM":"2022-02-24 02:35:03","TRT02SDTM":"2022-02-24 02:35:03","TRT02EDTM":"2023-02-24 08:35:03","AP01SDTM":"2020-02-24 14:35:03","AP01EDTM":"2022-02-24 02:35:03","AP02SDTM":"2022-02-24 02:35:03","AP02EDTM":"2023-02-24 08:35:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-24","EOSDY":1096,"LSTALVDT":"2023-03-16","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5305,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75512,"AVALU":"g/L","BASE2":3.01817,"BASE":2.98977,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.26305,"PCHG2":-8.71551,"CHG":-0.23464,"PCHG":-7.84822,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-07 14:35:03","ADY":622,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-232","SUBJID":"id-232","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.17424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-24 14:35:03","TRTEDTM":"2023-02-24 08:35:03","TRT01SDTM":"2020-02-24 14:35:03","TRT01EDTM":"2022-02-24 02:35:03","TRT02SDTM":"2022-02-24 02:35:03","TRT02EDTM":"2023-02-24 08:35:03","AP01SDTM":"2020-02-24 14:35:03","AP01EDTM":"2022-02-24 02:35:03","AP02SDTM":"2022-02-24 02:35:03","AP02EDTM":"2023-02-24 08:35:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-24","EOSDY":1096,"LSTALVDT":"2023-03-16","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8273,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88815,"AVALU":"g/L","BASE2":3.01817,"BASE":2.98977,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13002,"PCHG2":-4.30807,"CHG":-0.10162,"PCHG":-3.3989,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-27 14:35:03","ADY":672,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-232","SUBJID":"id-232","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.17424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-24 14:35:03","TRTEDTM":"2023-02-24 08:35:03","TRT01SDTM":"2020-02-24 14:35:03","TRT01EDTM":"2022-02-24 02:35:03","TRT02SDTM":"2022-02-24 02:35:03","TRT02EDTM":"2023-02-24 08:35:03","AP01SDTM":"2020-02-24 14:35:03","AP01EDTM":"2022-02-24 02:35:03","AP02SDTM":"2022-02-24 02:35:03","AP02EDTM":"2023-02-24 08:35:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-24","EOSDY":1096,"LSTALVDT":"2023-03-16","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5152,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89442,"AVALU":"g/L","BASE2":3.01817,"BASE":2.98977,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12375,"PCHG2":-4.10008,"CHG":-0.09534,"PCHG":-3.18894,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-19 14:35:03","ADY":726,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-232","SUBJID":"id-232","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.17424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-24 14:35:03","TRTEDTM":"2023-02-24 08:35:03","TRT01SDTM":"2020-02-24 14:35:03","TRT01EDTM":"2022-02-24 02:35:03","TRT02SDTM":"2022-02-24 02:35:03","TRT02EDTM":"2023-02-24 08:35:03","AP01SDTM":"2020-02-24 14:35:03","AP01EDTM":"2022-02-24 02:35:03","AP02SDTM":"2022-02-24 02:35:03","AP02EDTM":"2023-02-24 08:35:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-24","EOSDY":1096,"LSTALVDT":"2023-03-16","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4407,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00284,"AVALU":"g/L","BASE2":3.01817,"BASE":2.98977,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01533,"PCHG2":-0.50796,"CHG":0.01307,"PCHG":0.43731,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2022-05-21 14:35:03","ADY":817,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-232","SUBJID":"id-232","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.17424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-24 14:35:03","TRTEDTM":"2023-02-24 08:35:03","TRT01SDTM":"2020-02-24 14:35:03","TRT01EDTM":"2022-02-24 02:35:03","TRT02SDTM":"2022-02-24 02:35:03","TRT02EDTM":"2023-02-24 08:35:03","AP01SDTM":"2020-02-24 14:35:03","AP01EDTM":"2022-02-24 02:35:03","AP02SDTM":"2022-02-24 02:35:03","AP02EDTM":"2023-02-24 08:35:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-24","EOSDY":1096,"LSTALVDT":"2023-03-16","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2069,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85942,"AVALU":"g/L","BASE2":3.01817,"BASE":2.98977,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15875,"PCHG2":-5.25969,"CHG":-0.13034,"PCHG":-4.35957,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-13 14:35:03","ADY":901,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-233","SUBJID":"id-233","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.07682,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-09","TRTSDTM":"2021-02-11 21:54:30","TRTEDTM":"2022-02-15 19:43:12","TRT01SDTM":"2021-02-11 21:54:30","TRT01EDTM":"2021-02-15 13:43:12","TRT02SDTM":"2021-02-15 13:43:12","TRT02EDTM":"2022-02-15 19:43:12","AP01SDTM":"2021-02-11 21:54:30","AP01EDTM":"2021-02-15 13:43:12","AP02SDTM":"2021-02-15 13:43:12","AP02EDTM":"2022-02-15 19:43:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":369,"DCSREAS":"DEATH","DTHDT":"2022-03-25","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-25","DTHADY":406,"ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":109,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.84872,"AVALU":"U/L","BASE2":10.84872,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-10 21:54:30","ADY":27,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-233","SUBJID":"id-233","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.07682,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-09","TRTSDTM":"2021-02-11 21:54:30","TRTEDTM":"2022-02-15 19:43:12","TRT01SDTM":"2021-02-11 21:54:30","TRT01EDTM":"2021-02-15 13:43:12","TRT02SDTM":"2021-02-15 13:43:12","TRT02EDTM":"2022-02-15 19:43:12","AP01SDTM":"2021-02-11 21:54:30","AP01EDTM":"2021-02-15 13:43:12","AP02SDTM":"2021-02-15 13:43:12","AP02EDTM":"2022-02-15 19:43:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":369,"DCSREAS":"DEATH","DTHDT":"2022-03-25","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-25","DTHADY":406,"ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6555,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.26155,"AVALU":"U/L","BASE2":10.84872,"BASE":8.26155,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.58717,"PCHG2":-23.84766,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-13 21:54:30","ADY":30,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-233","SUBJID":"id-233","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.07682,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-09","TRTSDTM":"2021-02-11 21:54:30","TRTEDTM":"2022-02-15 19:43:12","TRT01SDTM":"2021-02-11 21:54:30","TRT01EDTM":"2021-02-15 13:43:12","TRT02SDTM":"2021-02-15 13:43:12","TRT02EDTM":"2022-02-15 19:43:12","AP01SDTM":"2021-02-11 21:54:30","AP01EDTM":"2021-02-15 13:43:12","AP02SDTM":"2021-02-15 13:43:12","AP02EDTM":"2022-02-15 19:43:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":369,"DCSREAS":"DEATH","DTHDT":"2022-03-25","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-25","DTHADY":406,"ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2759,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.0699,"AVALU":"U/L","BASE2":10.84872,"BASE":8.26155,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":17.22118,"PCHG2":158.73936,"CHG":19.80835,"PCHG":239.76548,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-01 21:54:30","ADY":110,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-233","SUBJID":"id-233","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.07682,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-09","TRTSDTM":"2021-02-11 21:54:30","TRTEDTM":"2022-02-15 19:43:12","TRT01SDTM":"2021-02-11 21:54:30","TRT01EDTM":"2021-02-15 13:43:12","TRT02SDTM":"2021-02-15 13:43:12","TRT02EDTM":"2022-02-15 19:43:12","AP01SDTM":"2021-02-11 21:54:30","AP01EDTM":"2021-02-15 13:43:12","AP02SDTM":"2021-02-15 13:43:12","AP02EDTM":"2022-02-15 19:43:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":369,"DCSREAS":"DEATH","DTHDT":"2022-03-25","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-25","DTHADY":406,"ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6627,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.35269,"AVALU":"U/L","BASE2":10.84872,"BASE":8.26155,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.50398,"PCHG2":41.51621,"CHG":7.09114,"PCHG":85.83304,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-24 21:54:30","ADY":163,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-233","SUBJID":"id-233","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.07682,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-09","TRTSDTM":"2021-02-11 21:54:30","TRTEDTM":"2022-02-15 19:43:12","TRT01SDTM":"2021-02-11 21:54:30","TRT01EDTM":"2021-02-15 13:43:12","TRT02SDTM":"2021-02-15 13:43:12","TRT02EDTM":"2022-02-15 19:43:12","AP01SDTM":"2021-02-11 21:54:30","AP01EDTM":"2021-02-15 13:43:12","AP02SDTM":"2021-02-15 13:43:12","AP02EDTM":"2022-02-15 19:43:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":369,"DCSREAS":"DEATH","DTHDT":"2022-03-25","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-25","DTHADY":406,"ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6764,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.59038,"AVALU":"U/L","BASE2":10.84872,"BASE":8.26155,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.74166,"PCHG2":34.48946,"CHG":6.32883,"PCHG":76.60582,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-25 21:54:30","ADY":164,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-233","SUBJID":"id-233","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.07682,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-09","TRTSDTM":"2021-02-11 21:54:30","TRTEDTM":"2022-02-15 19:43:12","TRT01SDTM":"2021-02-11 21:54:30","TRT01EDTM":"2021-02-15 13:43:12","TRT02SDTM":"2021-02-15 13:43:12","TRT02EDTM":"2022-02-15 19:43:12","AP01SDTM":"2021-02-11 21:54:30","AP01EDTM":"2021-02-15 13:43:12","AP02SDTM":"2021-02-15 13:43:12","AP02EDTM":"2022-02-15 19:43:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":369,"DCSREAS":"DEATH","DTHDT":"2022-03-25","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-25","DTHADY":406,"ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3426,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.99156,"AVALU":"U/L","BASE2":10.84872,"BASE":8.26155,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.14285,"PCHG2":176.45263,"CHG":21.73001,"PCHG":263.0258,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-24 21:54:30","ADY":194,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-233","SUBJID":"id-233","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.07682,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-09","TRTSDTM":"2021-02-11 21:54:30","TRTEDTM":"2022-02-15 19:43:12","TRT01SDTM":"2021-02-11 21:54:30","TRT01EDTM":"2021-02-15 13:43:12","TRT02SDTM":"2021-02-15 13:43:12","TRT02EDTM":"2022-02-15 19:43:12","AP01SDTM":"2021-02-11 21:54:30","AP01EDTM":"2021-02-15 13:43:12","AP02SDTM":"2021-02-15 13:43:12","AP02EDTM":"2022-02-15 19:43:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":369,"DCSREAS":"DEATH","DTHDT":"2022-03-25","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-25","DTHADY":406,"ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3099,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.25972,"AVALU":"U/L","BASE2":10.84872,"BASE":8.26155,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":22.411,"PCHG2":206.57749,"CHG":24.99817,"PCHG":302.58447,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-15 21:54:30","ADY":307,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-233","SUBJID":"id-233","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.07682,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-09","TRTSDTM":"2021-02-11 21:54:30","TRTEDTM":"2022-02-15 19:43:12","TRT01SDTM":"2021-02-11 21:54:30","TRT01EDTM":"2021-02-15 13:43:12","TRT02SDTM":"2021-02-15 13:43:12","TRT02EDTM":"2022-02-15 19:43:12","AP01SDTM":"2021-02-11 21:54:30","AP01EDTM":"2021-02-15 13:43:12","AP02SDTM":"2021-02-15 13:43:12","AP02EDTM":"2022-02-15 19:43:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":369,"DCSREAS":"DEATH","DTHDT":"2022-03-25","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-25","DTHADY":406,"ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":190,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.21293,"AVALU":"mg/L","BASE2":8.21293,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-10 21:54:30","ADY":27,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-233","SUBJID":"id-233","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.07682,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-09","TRTSDTM":"2021-02-11 21:54:30","TRTEDTM":"2022-02-15 19:43:12","TRT01SDTM":"2021-02-11 21:54:30","TRT01EDTM":"2021-02-15 13:43:12","TRT02SDTM":"2021-02-15 13:43:12","TRT02EDTM":"2022-02-15 19:43:12","AP01SDTM":"2021-02-11 21:54:30","AP01EDTM":"2021-02-15 13:43:12","AP02SDTM":"2021-02-15 13:43:12","AP02EDTM":"2022-02-15 19:43:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":369,"DCSREAS":"DEATH","DTHDT":"2022-03-25","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-25","DTHADY":406,"ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1194,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.63985,"AVALU":"mg/L","BASE2":8.21293,"BASE":9.63985,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.42692,"PCHG2":17.37409,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-13 21:54:30","ADY":30,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-233","SUBJID":"id-233","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.07682,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-09","TRTSDTM":"2021-02-11 21:54:30","TRTEDTM":"2022-02-15 19:43:12","TRT01SDTM":"2021-02-11 21:54:30","TRT01EDTM":"2021-02-15 13:43:12","TRT02SDTM":"2021-02-15 13:43:12","TRT02EDTM":"2022-02-15 19:43:12","AP01SDTM":"2021-02-11 21:54:30","AP01EDTM":"2021-02-15 13:43:12","AP02SDTM":"2021-02-15 13:43:12","AP02EDTM":"2022-02-15 19:43:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":369,"DCSREAS":"DEATH","DTHDT":"2022-03-25","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-25","DTHADY":406,"ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1359,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.96718,"AVALU":"mg/L","BASE2":8.21293,"BASE":9.63985,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.24575,"PCHG2":-2.99222,"CHG":-1.67267,"PCHG":-17.35162,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-06-01 21:54:30","ADY":110,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-233","SUBJID":"id-233","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.07682,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-09","TRTSDTM":"2021-02-11 21:54:30","TRTEDTM":"2022-02-15 19:43:12","TRT01SDTM":"2021-02-11 21:54:30","TRT01EDTM":"2021-02-15 13:43:12","TRT02SDTM":"2021-02-15 13:43:12","TRT02EDTM":"2022-02-15 19:43:12","AP01SDTM":"2021-02-11 21:54:30","AP01EDTM":"2021-02-15 13:43:12","AP02SDTM":"2021-02-15 13:43:12","AP02EDTM":"2022-02-15 19:43:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":369,"DCSREAS":"DEATH","DTHDT":"2022-03-25","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-25","DTHADY":406,"ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":257,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.97003,"AVALU":"mg/L","BASE2":8.21293,"BASE":9.63985,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.7571,"PCHG2":21.39429,"CHG":0.33018,"PCHG":3.42511,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-24 21:54:30","ADY":163,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-233","SUBJID":"id-233","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.07682,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-09","TRTSDTM":"2021-02-11 21:54:30","TRTEDTM":"2022-02-15 19:43:12","TRT01SDTM":"2021-02-11 21:54:30","TRT01EDTM":"2021-02-15 13:43:12","TRT02SDTM":"2021-02-15 13:43:12","TRT02EDTM":"2022-02-15 19:43:12","AP01SDTM":"2021-02-11 21:54:30","AP01EDTM":"2021-02-15 13:43:12","AP02SDTM":"2021-02-15 13:43:12","AP02EDTM":"2022-02-15 19:43:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":369,"DCSREAS":"DEATH","DTHDT":"2022-03-25","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-25","DTHADY":406,"ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4983,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.07818,"AVALU":"mg/L","BASE2":8.21293,"BASE":9.63985,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.86525,"PCHG2":10.53517,"CHG":-0.56168,"PCHG":-5.8266,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-25 21:54:30","ADY":164,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-233","SUBJID":"id-233","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.07682,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-09","TRTSDTM":"2021-02-11 21:54:30","TRTEDTM":"2022-02-15 19:43:12","TRT01SDTM":"2021-02-11 21:54:30","TRT01EDTM":"2021-02-15 13:43:12","TRT02SDTM":"2021-02-15 13:43:12","TRT02EDTM":"2022-02-15 19:43:12","AP01SDTM":"2021-02-11 21:54:30","AP01EDTM":"2021-02-15 13:43:12","AP02SDTM":"2021-02-15 13:43:12","AP02EDTM":"2022-02-15 19:43:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":369,"DCSREAS":"DEATH","DTHDT":"2022-03-25","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-25","DTHADY":406,"ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8274,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.78503,"AVALU":"mg/L","BASE2":8.21293,"BASE":9.63985,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.5721,"PCHG2":6.9658,"CHG":-0.85483,"PCHG":-8.86762,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-24 21:54:30","ADY":194,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-233","SUBJID":"id-233","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.07682,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-09","TRTSDTM":"2021-02-11 21:54:30","TRTEDTM":"2022-02-15 19:43:12","TRT01SDTM":"2021-02-11 21:54:30","TRT01EDTM":"2021-02-15 13:43:12","TRT02SDTM":"2021-02-15 13:43:12","TRT02EDTM":"2022-02-15 19:43:12","AP01SDTM":"2021-02-11 21:54:30","AP01EDTM":"2021-02-15 13:43:12","AP02SDTM":"2021-02-15 13:43:12","AP02EDTM":"2022-02-15 19:43:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":369,"DCSREAS":"DEATH","DTHDT":"2022-03-25","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-25","DTHADY":406,"ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1327,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.85883,"AVALU":"mg/L","BASE2":8.21293,"BASE":9.63985,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.6459,"PCHG2":20.04039,"CHG":0.21898,"PCHG":2.27162,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-15 21:54:30","ADY":307,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-233","SUBJID":"id-233","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.07682,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-09","TRTSDTM":"2021-02-11 21:54:30","TRTEDTM":"2022-02-15 19:43:12","TRT01SDTM":"2021-02-11 21:54:30","TRT01EDTM":"2021-02-15 13:43:12","TRT02SDTM":"2021-02-15 13:43:12","TRT02EDTM":"2022-02-15 19:43:12","AP01SDTM":"2021-02-11 21:54:30","AP01EDTM":"2021-02-15 13:43:12","AP02SDTM":"2021-02-15 13:43:12","AP02EDTM":"2022-02-15 19:43:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":369,"DCSREAS":"DEATH","DTHDT":"2022-03-25","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-25","DTHADY":406,"ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7346,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79044,"AVALU":"g/L","BASE2":2.79044,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-10 21:54:30","ADY":27,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-233","SUBJID":"id-233","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.07682,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-09","TRTSDTM":"2021-02-11 21:54:30","TRTEDTM":"2022-02-15 19:43:12","TRT01SDTM":"2021-02-11 21:54:30","TRT01EDTM":"2021-02-15 13:43:12","TRT02SDTM":"2021-02-15 13:43:12","TRT02EDTM":"2022-02-15 19:43:12","AP01SDTM":"2021-02-11 21:54:30","AP01EDTM":"2021-02-15 13:43:12","AP02SDTM":"2021-02-15 13:43:12","AP02EDTM":"2022-02-15 19:43:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":369,"DCSREAS":"DEATH","DTHDT":"2022-03-25","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-25","DTHADY":406,"ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6239,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96734,"AVALU":"g/L","BASE2":2.79044,"BASE":2.96734,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.1769,"PCHG2":6.33932,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-13 21:54:30","ADY":30,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-233","SUBJID":"id-233","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.07682,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-09","TRTSDTM":"2021-02-11 21:54:30","TRTEDTM":"2022-02-15 19:43:12","TRT01SDTM":"2021-02-11 21:54:30","TRT01EDTM":"2021-02-15 13:43:12","TRT02SDTM":"2021-02-15 13:43:12","TRT02EDTM":"2022-02-15 19:43:12","AP01SDTM":"2021-02-11 21:54:30","AP01EDTM":"2021-02-15 13:43:12","AP02SDTM":"2021-02-15 13:43:12","AP02EDTM":"2022-02-15 19:43:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":369,"DCSREAS":"DEATH","DTHDT":"2022-03-25","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-25","DTHADY":406,"ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6636,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82523,"AVALU":"g/L","BASE2":2.79044,"BASE":2.96734,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03478,"PCHG2":1.24643,"CHG":-0.14211,"PCHG":-4.78928,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-01 21:54:30","ADY":110,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-233","SUBJID":"id-233","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.07682,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-09","TRTSDTM":"2021-02-11 21:54:30","TRTEDTM":"2022-02-15 19:43:12","TRT01SDTM":"2021-02-11 21:54:30","TRT01EDTM":"2021-02-15 13:43:12","TRT02SDTM":"2021-02-15 13:43:12","TRT02EDTM":"2022-02-15 19:43:12","AP01SDTM":"2021-02-11 21:54:30","AP01EDTM":"2021-02-15 13:43:12","AP02SDTM":"2021-02-15 13:43:12","AP02EDTM":"2022-02-15 19:43:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":369,"DCSREAS":"DEATH","DTHDT":"2022-03-25","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-25","DTHADY":406,"ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":792,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.71627,"AVALU":"g/L","BASE2":2.79044,"BASE":2.96734,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07417,"PCHG2":-2.65804,"CHG":-0.25107,"PCHG":-8.46099,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-24 21:54:30","ADY":163,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-233","SUBJID":"id-233","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.07682,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-09","TRTSDTM":"2021-02-11 21:54:30","TRTEDTM":"2022-02-15 19:43:12","TRT01SDTM":"2021-02-11 21:54:30","TRT01EDTM":"2021-02-15 13:43:12","TRT02SDTM":"2021-02-15 13:43:12","TRT02EDTM":"2022-02-15 19:43:12","AP01SDTM":"2021-02-11 21:54:30","AP01EDTM":"2021-02-15 13:43:12","AP02SDTM":"2021-02-15 13:43:12","AP02EDTM":"2022-02-15 19:43:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":369,"DCSREAS":"DEATH","DTHDT":"2022-03-25","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-25","DTHADY":406,"ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7669,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86764,"AVALU":"g/L","BASE2":2.79044,"BASE":2.96734,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0772,"PCHG2":2.76646,"CHG":-0.0997,"PCHG":-3.35987,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-25 21:54:30","ADY":164,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-233","SUBJID":"id-233","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.07682,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-09","TRTSDTM":"2021-02-11 21:54:30","TRTEDTM":"2022-02-15 19:43:12","TRT01SDTM":"2021-02-11 21:54:30","TRT01EDTM":"2021-02-15 13:43:12","TRT02SDTM":"2021-02-15 13:43:12","TRT02EDTM":"2022-02-15 19:43:12","AP01SDTM":"2021-02-11 21:54:30","AP01EDTM":"2021-02-15 13:43:12","AP02SDTM":"2021-02-15 13:43:12","AP02EDTM":"2022-02-15 19:43:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":369,"DCSREAS":"DEATH","DTHDT":"2022-03-25","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-25","DTHADY":406,"ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1033,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97894,"AVALU":"g/L","BASE2":2.79044,"BASE":2.96734,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18849,"PCHG2":6.75501,"CHG":0.0116,"PCHG":0.39091,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-24 21:54:30","ADY":194,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-233","SUBJID":"id-233","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.07682,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-09","TRTSDTM":"2021-02-11 21:54:30","TRTEDTM":"2022-02-15 19:43:12","TRT01SDTM":"2021-02-11 21:54:30","TRT01EDTM":"2021-02-15 13:43:12","TRT02SDTM":"2021-02-15 13:43:12","TRT02EDTM":"2022-02-15 19:43:12","AP01SDTM":"2021-02-11 21:54:30","AP01EDTM":"2021-02-15 13:43:12","AP02SDTM":"2021-02-15 13:43:12","AP02EDTM":"2022-02-15 19:43:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":369,"DCSREAS":"DEATH","DTHDT":"2022-03-25","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-25","DTHADY":406,"ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8066,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90921,"AVALU":"g/L","BASE2":2.79044,"BASE":2.96734,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11876,"PCHG2":4.25597,"CHG":-0.05813,"PCHG":-1.95915,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-15 21:54:30","ADY":307,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-235","SUBJID":"id-235","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.71119,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-13 00:37:20","TRTEDTM":"2022-02-16 05:56:04","TRT01SDTM":"2019-07-13 00:37:20","TRT01EDTM":"2021-02-15 23:56:04","TRT02SDTM":"2021-02-15 23:56:04","TRT02EDTM":"2022-02-16 05:56:04","AP01SDTM":"2019-07-13 00:37:20","AP01EDTM":"2021-02-15 23:56:04","AP02SDTM":"2021-02-15 23:56:04","AP02EDTM":"2022-02-16 05:56:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":950,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":20,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":968,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3386,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.28002,"AVALU":"U/L","BASE2":18.28002,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-15 00:37:20","ADY":94,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-235","SUBJID":"id-235","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.71119,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-13 00:37:20","TRTEDTM":"2022-02-16 05:56:04","TRT01SDTM":"2019-07-13 00:37:20","TRT01EDTM":"2021-02-15 23:56:04","TRT02SDTM":"2021-02-15 23:56:04","TRT02EDTM":"2022-02-16 05:56:04","AP01SDTM":"2019-07-13 00:37:20","AP01EDTM":"2021-02-15 23:56:04","AP02SDTM":"2021-02-15 23:56:04","AP02EDTM":"2022-02-16 05:56:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":950,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":20,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":968,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4587,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.81099,"AVALU":"U/L","BASE2":18.28002,"BASE":10.81099,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-7.46903,"PCHG2":-40.85896,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-18 00:37:20","ADY":128,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-235","SUBJID":"id-235","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.71119,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-13 00:37:20","TRTEDTM":"2022-02-16 05:56:04","TRT01SDTM":"2019-07-13 00:37:20","TRT01EDTM":"2021-02-15 23:56:04","TRT02SDTM":"2021-02-15 23:56:04","TRT02EDTM":"2022-02-16 05:56:04","AP01SDTM":"2019-07-13 00:37:20","AP01EDTM":"2021-02-15 23:56:04","AP02SDTM":"2021-02-15 23:56:04","AP02EDTM":"2022-02-16 05:56:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":950,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":20,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":968,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2912,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.77659,"AVALU":"U/L","BASE2":18.28002,"BASE":10.81099,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.50343,"PCHG2":-13.69488,"CHG":4.9656,"PCHG":45.93102,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-29 00:37:20","ADY":139,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-235","SUBJID":"id-235","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.71119,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-13 00:37:20","TRTEDTM":"2022-02-16 05:56:04","TRT01SDTM":"2019-07-13 00:37:20","TRT01EDTM":"2021-02-15 23:56:04","TRT02SDTM":"2021-02-15 23:56:04","TRT02EDTM":"2022-02-16 05:56:04","AP01SDTM":"2019-07-13 00:37:20","AP01EDTM":"2021-02-15 23:56:04","AP02SDTM":"2021-02-15 23:56:04","AP02EDTM":"2022-02-16 05:56:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":950,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":20,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":968,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2057,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.95501,"AVALU":"U/L","BASE2":18.28002,"BASE":10.81099,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.67499,"PCHG2":3.6925,"CHG":8.14402,"PCHG":75.33089,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-20 00:37:20","ADY":222,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-235","SUBJID":"id-235","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.71119,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-13 00:37:20","TRTEDTM":"2022-02-16 05:56:04","TRT01SDTM":"2019-07-13 00:37:20","TRT01EDTM":"2021-02-15 23:56:04","TRT02SDTM":"2021-02-15 23:56:04","TRT02EDTM":"2022-02-16 05:56:04","AP01SDTM":"2019-07-13 00:37:20","AP01EDTM":"2021-02-15 23:56:04","AP02SDTM":"2021-02-15 23:56:04","AP02EDTM":"2022-02-16 05:56:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":950,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":20,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":968,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1360,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.03564,"AVALU":"U/L","BASE2":18.28002,"BASE":10.81099,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.24438,"PCHG2":-50.57097,"CHG":-1.77536,"PCHG":-16.42177,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-27 00:37:20","ADY":229,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-235","SUBJID":"id-235","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.71119,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-13 00:37:20","TRTEDTM":"2022-02-16 05:56:04","TRT01SDTM":"2019-07-13 00:37:20","TRT01EDTM":"2021-02-15 23:56:04","TRT02SDTM":"2021-02-15 23:56:04","TRT02EDTM":"2022-02-16 05:56:04","AP01SDTM":"2019-07-13 00:37:20","AP01EDTM":"2021-02-15 23:56:04","AP02SDTM":"2021-02-15 23:56:04","AP02EDTM":"2022-02-16 05:56:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":950,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":20,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":968,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6754,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.00039,"AVALU":"U/L","BASE2":18.28002,"BASE":10.81099,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-15.27963,"PCHG2":-83.58652,"CHG":-7.81061,"PCHG":-72.24689,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-06-25 00:37:20","ADY":348,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-235","SUBJID":"id-235","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.71119,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-13 00:37:20","TRTEDTM":"2022-02-16 05:56:04","TRT01SDTM":"2019-07-13 00:37:20","TRT01EDTM":"2021-02-15 23:56:04","TRT02SDTM":"2021-02-15 23:56:04","TRT02EDTM":"2022-02-16 05:56:04","AP01SDTM":"2019-07-13 00:37:20","AP01EDTM":"2021-02-15 23:56:04","AP02SDTM":"2021-02-15 23:56:04","AP02EDTM":"2022-02-16 05:56:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":950,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":20,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":968,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2696,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.74341,"AVALU":"U/L","BASE2":18.28002,"BASE":10.81099,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.53661,"PCHG2":-74.05137,"CHG":-6.06758,"PCHG":-56.12416,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-07-28 00:37:20","ADY":381,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-235","SUBJID":"id-235","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.71119,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-13 00:37:20","TRTEDTM":"2022-02-16 05:56:04","TRT01SDTM":"2019-07-13 00:37:20","TRT01EDTM":"2021-02-15 23:56:04","TRT02SDTM":"2021-02-15 23:56:04","TRT02EDTM":"2022-02-16 05:56:04","AP01SDTM":"2019-07-13 00:37:20","AP01EDTM":"2021-02-15 23:56:04","AP02SDTM":"2021-02-15 23:56:04","AP02EDTM":"2022-02-16 05:56:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":950,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":20,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":968,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":419,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.04041,"AVALU":"mg/L","BASE2":9.04041,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-15 00:37:20","ADY":94,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-235","SUBJID":"id-235","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.71119,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-13 00:37:20","TRTEDTM":"2022-02-16 05:56:04","TRT01SDTM":"2019-07-13 00:37:20","TRT01EDTM":"2021-02-15 23:56:04","TRT02SDTM":"2021-02-15 23:56:04","TRT02EDTM":"2022-02-16 05:56:04","AP01SDTM":"2019-07-13 00:37:20","AP01EDTM":"2021-02-15 23:56:04","AP02SDTM":"2021-02-15 23:56:04","AP02EDTM":"2022-02-16 05:56:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":950,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":20,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":968,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4728,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.22192,"AVALU":"mg/L","BASE2":9.04041,"BASE":8.22192,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.81849,"PCHG2":-9.05371,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-18 00:37:20","ADY":128,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-235","SUBJID":"id-235","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.71119,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-13 00:37:20","TRTEDTM":"2022-02-16 05:56:04","TRT01SDTM":"2019-07-13 00:37:20","TRT01EDTM":"2021-02-15 23:56:04","TRT02SDTM":"2021-02-15 23:56:04","TRT02EDTM":"2022-02-16 05:56:04","AP01SDTM":"2019-07-13 00:37:20","AP01EDTM":"2021-02-15 23:56:04","AP02SDTM":"2021-02-15 23:56:04","AP02EDTM":"2022-02-16 05:56:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":950,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":20,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":968,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":538,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.73335,"AVALU":"mg/L","BASE2":9.04041,"BASE":8.22192,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.30706,"PCHG2":-25.51945,"CHG":-1.48857,"PCHG":-18.10491,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2019-11-29 00:37:20","ADY":139,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-235","SUBJID":"id-235","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.71119,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-13 00:37:20","TRTEDTM":"2022-02-16 05:56:04","TRT01SDTM":"2019-07-13 00:37:20","TRT01EDTM":"2021-02-15 23:56:04","TRT02SDTM":"2021-02-15 23:56:04","TRT02EDTM":"2022-02-16 05:56:04","AP01SDTM":"2019-07-13 00:37:20","AP01EDTM":"2021-02-15 23:56:04","AP02SDTM":"2021-02-15 23:56:04","AP02EDTM":"2022-02-16 05:56:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":950,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":20,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":968,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6733,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.8513,"AVALU":"mg/L","BASE2":9.04041,"BASE":8.22192,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.18911,"PCHG2":-13.15329,"CHG":-0.37062,"PCHG":-4.50769,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-02-20 00:37:20","ADY":222,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-235","SUBJID":"id-235","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.71119,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-13 00:37:20","TRTEDTM":"2022-02-16 05:56:04","TRT01SDTM":"2019-07-13 00:37:20","TRT01EDTM":"2021-02-15 23:56:04","TRT02SDTM":"2021-02-15 23:56:04","TRT02EDTM":"2022-02-16 05:56:04","AP01SDTM":"2019-07-13 00:37:20","AP01EDTM":"2021-02-15 23:56:04","AP02SDTM":"2021-02-15 23:56:04","AP02EDTM":"2022-02-16 05:56:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":950,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":20,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":968,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3272,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.35256,"AVALU":"mg/L","BASE2":9.04041,"BASE":8.22192,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.68785,"PCHG2":-7.60862,"CHG":0.13064,"PCHG":1.58894,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-27 00:37:20","ADY":229,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-235","SUBJID":"id-235","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.71119,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-13 00:37:20","TRTEDTM":"2022-02-16 05:56:04","TRT01SDTM":"2019-07-13 00:37:20","TRT01EDTM":"2021-02-15 23:56:04","TRT02SDTM":"2021-02-15 23:56:04","TRT02EDTM":"2022-02-16 05:56:04","AP01SDTM":"2019-07-13 00:37:20","AP01EDTM":"2021-02-15 23:56:04","AP02SDTM":"2021-02-15 23:56:04","AP02EDTM":"2022-02-16 05:56:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":950,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":20,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":968,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1382,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.7172,"AVALU":"mg/L","BASE2":9.04041,"BASE":8.22192,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.32322,"PCHG2":-3.57525,"CHG":0.49527,"PCHG":6.02383,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-25 00:37:20","ADY":348,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-235","SUBJID":"id-235","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.71119,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-13 00:37:20","TRTEDTM":"2022-02-16 05:56:04","TRT01SDTM":"2019-07-13 00:37:20","TRT01EDTM":"2021-02-15 23:56:04","TRT02SDTM":"2021-02-15 23:56:04","TRT02EDTM":"2022-02-16 05:56:04","AP01SDTM":"2019-07-13 00:37:20","AP01EDTM":"2021-02-15 23:56:04","AP02SDTM":"2021-02-15 23:56:04","AP02EDTM":"2022-02-16 05:56:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":950,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":20,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":968,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4328,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.17849,"AVALU":"mg/L","BASE2":9.04041,"BASE":8.22192,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.86192,"PCHG2":-9.53411,"CHG":-0.04343,"PCHG":-0.52823,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-28 00:37:20","ADY":381,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-235","SUBJID":"id-235","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.71119,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-13 00:37:20","TRTEDTM":"2022-02-16 05:56:04","TRT01SDTM":"2019-07-13 00:37:20","TRT01EDTM":"2021-02-15 23:56:04","TRT02SDTM":"2021-02-15 23:56:04","TRT02EDTM":"2022-02-16 05:56:04","AP01SDTM":"2019-07-13 00:37:20","AP01EDTM":"2021-02-15 23:56:04","AP02SDTM":"2021-02-15 23:56:04","AP02EDTM":"2022-02-16 05:56:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":950,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":20,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":968,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6144,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91173,"AVALU":"g/L","BASE2":2.91173,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-15 00:37:20","ADY":94,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-235","SUBJID":"id-235","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.71119,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-13 00:37:20","TRTEDTM":"2022-02-16 05:56:04","TRT01SDTM":"2019-07-13 00:37:20","TRT01EDTM":"2021-02-15 23:56:04","TRT02SDTM":"2021-02-15 23:56:04","TRT02EDTM":"2022-02-16 05:56:04","AP01SDTM":"2019-07-13 00:37:20","AP01EDTM":"2021-02-15 23:56:04","AP02SDTM":"2021-02-15 23:56:04","AP02EDTM":"2022-02-16 05:56:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":950,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":20,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":968,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2713,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78754,"AVALU":"g/L","BASE2":2.91173,"BASE":2.78754,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.12419,"PCHG2":-4.26514,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-18 00:37:20","ADY":128,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-235","SUBJID":"id-235","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.71119,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-13 00:37:20","TRTEDTM":"2022-02-16 05:56:04","TRT01SDTM":"2019-07-13 00:37:20","TRT01EDTM":"2021-02-15 23:56:04","TRT02SDTM":"2021-02-15 23:56:04","TRT02EDTM":"2022-02-16 05:56:04","AP01SDTM":"2019-07-13 00:37:20","AP01EDTM":"2021-02-15 23:56:04","AP02SDTM":"2021-02-15 23:56:04","AP02EDTM":"2022-02-16 05:56:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":950,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":20,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":968,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":100,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87118,"AVALU":"g/L","BASE2":2.91173,"BASE":2.78754,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04055,"PCHG2":-1.39273,"CHG":0.08364,"PCHG":3.00039,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-29 00:37:20","ADY":139,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-235","SUBJID":"id-235","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.71119,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-13 00:37:20","TRTEDTM":"2022-02-16 05:56:04","TRT01SDTM":"2019-07-13 00:37:20","TRT01EDTM":"2021-02-15 23:56:04","TRT02SDTM":"2021-02-15 23:56:04","TRT02EDTM":"2022-02-16 05:56:04","AP01SDTM":"2019-07-13 00:37:20","AP01EDTM":"2021-02-15 23:56:04","AP02SDTM":"2021-02-15 23:56:04","AP02EDTM":"2022-02-16 05:56:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":950,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":20,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":968,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8376,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01043,"AVALU":"g/L","BASE2":2.91173,"BASE":2.78754,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09869,"PCHG2":3.38955,"CHG":0.22288,"PCHG":7.99572,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-02-20 00:37:20","ADY":222,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-235","SUBJID":"id-235","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.71119,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-13 00:37:20","TRTEDTM":"2022-02-16 05:56:04","TRT01SDTM":"2019-07-13 00:37:20","TRT01EDTM":"2021-02-15 23:56:04","TRT02SDTM":"2021-02-15 23:56:04","TRT02EDTM":"2022-02-16 05:56:04","AP01SDTM":"2019-07-13 00:37:20","AP01EDTM":"2021-02-15 23:56:04","AP02SDTM":"2021-02-15 23:56:04","AP02EDTM":"2022-02-16 05:56:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":950,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":20,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":968,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4776,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0079,"AVALU":"g/L","BASE2":2.91173,"BASE":2.78754,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09617,"PCHG2":3.30276,"CHG":0.22036,"PCHG":7.90506,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-02-27 00:37:20","ADY":229,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-235","SUBJID":"id-235","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.71119,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-13 00:37:20","TRTEDTM":"2022-02-16 05:56:04","TRT01SDTM":"2019-07-13 00:37:20","TRT01EDTM":"2021-02-15 23:56:04","TRT02SDTM":"2021-02-15 23:56:04","TRT02EDTM":"2022-02-16 05:56:04","AP01SDTM":"2019-07-13 00:37:20","AP01EDTM":"2021-02-15 23:56:04","AP02SDTM":"2021-02-15 23:56:04","AP02EDTM":"2022-02-16 05:56:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":950,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":20,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":968,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8263,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78159,"AVALU":"g/L","BASE2":2.91173,"BASE":2.78754,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13014,"PCHG2":-4.46943,"CHG":-0.00595,"PCHG":-0.21339,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-25 00:37:20","ADY":348,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-235","SUBJID":"id-235","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.71119,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-13 00:37:20","TRTEDTM":"2022-02-16 05:56:04","TRT01SDTM":"2019-07-13 00:37:20","TRT01EDTM":"2021-02-15 23:56:04","TRT02SDTM":"2021-02-15 23:56:04","TRT02EDTM":"2022-02-16 05:56:04","AP01SDTM":"2019-07-13 00:37:20","AP01EDTM":"2021-02-15 23:56:04","AP02SDTM":"2021-02-15 23:56:04","AP02EDTM":"2022-02-16 05:56:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":950,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":20,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":968,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7569,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.06359,"AVALU":"g/L","BASE2":2.91173,"BASE":2.78754,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15186,"PCHG2":5.21539,"CHG":0.27605,"PCHG":9.9029,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-07-28 00:37:20","ADY":381,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-25","SUBJID":"id-25","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.7821,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-11-02 12:51:08","TRTEDTM":"2022-02-16 10:48:14","TRT01SDTM":"2020-11-02 12:51:08","TRT01EDTM":"2021-02-16 04:48:14","TRT02SDTM":"2021-02-16 04:48:14","TRT02EDTM":"2022-02-16 10:48:14","AP01SDTM":"2020-11-02 12:51:08","AP01EDTM":"2021-02-16 04:48:14","AP02SDTM":"2021-02-16 04:48:14","AP02EDTM":"2022-02-16 10:48:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":471,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6366,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.39589,"AVALU":"U/L","BASE2":25.39589,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-14 12:51:08","ADY":42,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-25","SUBJID":"id-25","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.7821,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-11-02 12:51:08","TRTEDTM":"2022-02-16 10:48:14","TRT01SDTM":"2020-11-02 12:51:08","TRT01EDTM":"2021-02-16 04:48:14","TRT02SDTM":"2021-02-16 04:48:14","TRT02EDTM":"2022-02-16 10:48:14","AP01SDTM":"2020-11-02 12:51:08","AP01EDTM":"2021-02-16 04:48:14","AP02SDTM":"2021-02-16 04:48:14","AP02EDTM":"2022-02-16 10:48:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":471,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1943,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.87643,"AVALU":"U/L","BASE2":25.39589,"BASE":23.87643,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.51946,"PCHG2":-5.98311,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-05 12:51:08","ADY":154,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-25","SUBJID":"id-25","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.7821,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-11-02 12:51:08","TRTEDTM":"2022-02-16 10:48:14","TRT01SDTM":"2020-11-02 12:51:08","TRT01EDTM":"2021-02-16 04:48:14","TRT02SDTM":"2021-02-16 04:48:14","TRT02EDTM":"2022-02-16 10:48:14","AP01SDTM":"2020-11-02 12:51:08","AP01EDTM":"2021-02-16 04:48:14","AP02SDTM":"2021-02-16 04:48:14","AP02EDTM":"2022-02-16 10:48:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":471,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6609,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.35998,"AVALU":"U/L","BASE2":25.39589,"BASE":23.87643,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.03591,"PCHG2":-35.5802,"CHG":-7.51645,"PCHG":-31.48062,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-22 12:51:08","ADY":171,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-25","SUBJID":"id-25","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.7821,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-11-02 12:51:08","TRTEDTM":"2022-02-16 10:48:14","TRT01SDTM":"2020-11-02 12:51:08","TRT01EDTM":"2021-02-16 04:48:14","TRT02SDTM":"2021-02-16 04:48:14","TRT02EDTM":"2022-02-16 10:48:14","AP01SDTM":"2020-11-02 12:51:08","AP01EDTM":"2021-02-16 04:48:14","AP02SDTM":"2021-02-16 04:48:14","AP02EDTM":"2022-02-16 10:48:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":471,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4377,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.25415,"AVALU":"U/L","BASE2":25.39589,"BASE":23.87643,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.14174,"PCHG2":-24.18399,"CHG":-4.62228,"PCHG":-19.35916,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-16 12:51:08","ADY":226,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-25","SUBJID":"id-25","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.7821,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-11-02 12:51:08","TRTEDTM":"2022-02-16 10:48:14","TRT01SDTM":"2020-11-02 12:51:08","TRT01EDTM":"2021-02-16 04:48:14","TRT02SDTM":"2021-02-16 04:48:14","TRT02EDTM":"2022-02-16 10:48:14","AP01SDTM":"2020-11-02 12:51:08","AP01EDTM":"2021-02-16 04:48:14","AP02SDTM":"2021-02-16 04:48:14","AP02EDTM":"2022-02-16 10:48:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":471,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6897,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.01944,"AVALU":"U/L","BASE2":25.39589,"BASE":23.87643,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.37645,"PCHG2":-9.35761,"CHG":-0.85699,"PCHG":-3.58926,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-26 12:51:08","ADY":389,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-25","SUBJID":"id-25","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.7821,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-11-02 12:51:08","TRTEDTM":"2022-02-16 10:48:14","TRT01SDTM":"2020-11-02 12:51:08","TRT01EDTM":"2021-02-16 04:48:14","TRT02SDTM":"2021-02-16 04:48:14","TRT02EDTM":"2022-02-16 10:48:14","AP01SDTM":"2020-11-02 12:51:08","AP01EDTM":"2021-02-16 04:48:14","AP02SDTM":"2021-02-16 04:48:14","AP02EDTM":"2022-02-16 10:48:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":471,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":744,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.16625,"AVALU":"U/L","BASE2":25.39589,"BASE":23.87643,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.22964,"PCHG2":-0.90426,"CHG":1.28982,"PCHG":5.40206,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-24 12:51:08","ADY":417,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-25","SUBJID":"id-25","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.7821,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-11-02 12:51:08","TRTEDTM":"2022-02-16 10:48:14","TRT01SDTM":"2020-11-02 12:51:08","TRT01EDTM":"2021-02-16 04:48:14","TRT02SDTM":"2021-02-16 04:48:14","TRT02EDTM":"2022-02-16 10:48:14","AP01SDTM":"2020-11-02 12:51:08","AP01EDTM":"2021-02-16 04:48:14","AP02SDTM":"2021-02-16 04:48:14","AP02EDTM":"2022-02-16 10:48:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":471,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4835,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.41935,"AVALU":"U/L","BASE2":25.39589,"BASE":23.87643,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.97654,"PCHG2":-35.34642,"CHG":-7.45708,"PCHG":-31.23195,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-10 12:51:08","ADY":465,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-25","SUBJID":"id-25","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.7821,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-11-02 12:51:08","TRTEDTM":"2022-02-16 10:48:14","TRT01SDTM":"2020-11-02 12:51:08","TRT01EDTM":"2021-02-16 04:48:14","TRT02SDTM":"2021-02-16 04:48:14","TRT02EDTM":"2022-02-16 10:48:14","AP01SDTM":"2020-11-02 12:51:08","AP01EDTM":"2021-02-16 04:48:14","AP02SDTM":"2021-02-16 04:48:14","AP02EDTM":"2022-02-16 10:48:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":471,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7865,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.87107,"AVALU":"mg/L","BASE2":8.87107,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-14 12:51:08","ADY":42,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-25","SUBJID":"id-25","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.7821,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-11-02 12:51:08","TRTEDTM":"2022-02-16 10:48:14","TRT01SDTM":"2020-11-02 12:51:08","TRT01EDTM":"2021-02-16 04:48:14","TRT02SDTM":"2021-02-16 04:48:14","TRT02EDTM":"2022-02-16 10:48:14","AP01SDTM":"2020-11-02 12:51:08","AP01EDTM":"2021-02-16 04:48:14","AP02SDTM":"2021-02-16 04:48:14","AP02EDTM":"2022-02-16 10:48:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":471,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5058,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.93953,"AVALU":"mg/L","BASE2":8.87107,"BASE":9.93953,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.06846,"PCHG2":12.04428,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-05 12:51:08","ADY":154,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-25","SUBJID":"id-25","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.7821,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-11-02 12:51:08","TRTEDTM":"2022-02-16 10:48:14","TRT01SDTM":"2020-11-02 12:51:08","TRT01EDTM":"2021-02-16 04:48:14","TRT02SDTM":"2021-02-16 04:48:14","TRT02EDTM":"2022-02-16 10:48:14","AP01SDTM":"2020-11-02 12:51:08","AP01EDTM":"2021-02-16 04:48:14","AP02SDTM":"2021-02-16 04:48:14","AP02EDTM":"2022-02-16 10:48:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":471,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1409,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.46067,"AVALU":"mg/L","BASE2":8.87107,"BASE":9.93953,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.5896,"PCHG2":17.91889,"CHG":0.52114,"PCHG":5.24312,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-04-22 12:51:08","ADY":171,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-25","SUBJID":"id-25","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.7821,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-11-02 12:51:08","TRTEDTM":"2022-02-16 10:48:14","TRT01SDTM":"2020-11-02 12:51:08","TRT01EDTM":"2021-02-16 04:48:14","TRT02SDTM":"2021-02-16 04:48:14","TRT02EDTM":"2022-02-16 10:48:14","AP01SDTM":"2020-11-02 12:51:08","AP01EDTM":"2021-02-16 04:48:14","AP02SDTM":"2021-02-16 04:48:14","AP02EDTM":"2022-02-16 10:48:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":471,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3022,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.60535,"AVALU":"mg/L","BASE2":8.87107,"BASE":9.93953,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.26573,"PCHG2":-2.99541,"CHG":-1.33418,"PCHG":-13.42299,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-16 12:51:08","ADY":226,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-25","SUBJID":"id-25","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.7821,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-11-02 12:51:08","TRTEDTM":"2022-02-16 10:48:14","TRT01SDTM":"2020-11-02 12:51:08","TRT01EDTM":"2021-02-16 04:48:14","TRT02SDTM":"2021-02-16 04:48:14","TRT02EDTM":"2022-02-16 10:48:14","AP01SDTM":"2020-11-02 12:51:08","AP01EDTM":"2021-02-16 04:48:14","AP02SDTM":"2021-02-16 04:48:14","AP02EDTM":"2022-02-16 10:48:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":471,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":107,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.55851,"AVALU":"mg/L","BASE2":8.87107,"BASE":9.93953,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.68743,"PCHG2":19.02173,"CHG":0.61898,"PCHG":6.22741,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-11-26 12:51:08","ADY":389,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-25","SUBJID":"id-25","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.7821,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-11-02 12:51:08","TRTEDTM":"2022-02-16 10:48:14","TRT01SDTM":"2020-11-02 12:51:08","TRT01EDTM":"2021-02-16 04:48:14","TRT02SDTM":"2021-02-16 04:48:14","TRT02EDTM":"2022-02-16 10:48:14","AP01SDTM":"2020-11-02 12:51:08","AP01EDTM":"2021-02-16 04:48:14","AP02SDTM":"2021-02-16 04:48:14","AP02EDTM":"2022-02-16 10:48:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":471,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4642,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.22697,"AVALU":"mg/L","BASE2":8.87107,"BASE":9.93953,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.64411,"PCHG2":-18.53337,"CHG":-2.71257,"PCHG":-27.29068,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-12-24 12:51:08","ADY":417,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-25","SUBJID":"id-25","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.7821,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-11-02 12:51:08","TRTEDTM":"2022-02-16 10:48:14","TRT01SDTM":"2020-11-02 12:51:08","TRT01EDTM":"2021-02-16 04:48:14","TRT02SDTM":"2021-02-16 04:48:14","TRT02EDTM":"2022-02-16 10:48:14","AP01SDTM":"2020-11-02 12:51:08","AP01EDTM":"2021-02-16 04:48:14","AP02SDTM":"2021-02-16 04:48:14","AP02EDTM":"2022-02-16 10:48:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":471,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":934,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.59885,"AVALU":"mg/L","BASE2":8.87107,"BASE":9.93953,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.72778,"PCHG2":19.47653,"CHG":0.65932,"PCHG":6.63332,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2022-02-10 12:51:08","ADY":465,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-25","SUBJID":"id-25","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.7821,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-11-02 12:51:08","TRTEDTM":"2022-02-16 10:48:14","TRT01SDTM":"2020-11-02 12:51:08","TRT01EDTM":"2021-02-16 04:48:14","TRT02SDTM":"2021-02-16 04:48:14","TRT02EDTM":"2022-02-16 10:48:14","AP01SDTM":"2020-11-02 12:51:08","AP01EDTM":"2021-02-16 04:48:14","AP02SDTM":"2021-02-16 04:48:14","AP02EDTM":"2022-02-16 10:48:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":471,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7384,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78509,"AVALU":"g/L","BASE2":2.78509,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-14 12:51:08","ADY":42,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-25","SUBJID":"id-25","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.7821,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-11-02 12:51:08","TRTEDTM":"2022-02-16 10:48:14","TRT01SDTM":"2020-11-02 12:51:08","TRT01EDTM":"2021-02-16 04:48:14","TRT02SDTM":"2021-02-16 04:48:14","TRT02EDTM":"2022-02-16 10:48:14","AP01SDTM":"2020-11-02 12:51:08","AP01EDTM":"2021-02-16 04:48:14","AP02SDTM":"2021-02-16 04:48:14","AP02EDTM":"2022-02-16 10:48:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":471,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5139,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8632,"AVALU":"g/L","BASE2":2.78509,"BASE":2.8632,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.07811,"PCHG2":2.80446,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-05 12:51:08","ADY":154,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-25","SUBJID":"id-25","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.7821,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-11-02 12:51:08","TRTEDTM":"2022-02-16 10:48:14","TRT01SDTM":"2020-11-02 12:51:08","TRT01EDTM":"2021-02-16 04:48:14","TRT02SDTM":"2021-02-16 04:48:14","TRT02EDTM":"2022-02-16 10:48:14","AP01SDTM":"2020-11-02 12:51:08","AP01EDTM":"2021-02-16 04:48:14","AP02SDTM":"2021-02-16 04:48:14","AP02EDTM":"2022-02-16 10:48:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":471,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2154,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97347,"AVALU":"g/L","BASE2":2.78509,"BASE":2.8632,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18838,"PCHG2":6.76382,"CHG":0.11027,"PCHG":3.85135,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-22 12:51:08","ADY":171,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-25","SUBJID":"id-25","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.7821,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-11-02 12:51:08","TRTEDTM":"2022-02-16 10:48:14","TRT01SDTM":"2020-11-02 12:51:08","TRT01EDTM":"2021-02-16 04:48:14","TRT02SDTM":"2021-02-16 04:48:14","TRT02EDTM":"2022-02-16 10:48:14","AP01SDTM":"2020-11-02 12:51:08","AP01EDTM":"2021-02-16 04:48:14","AP02SDTM":"2021-02-16 04:48:14","AP02EDTM":"2022-02-16 10:48:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":471,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":199,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83594,"AVALU":"g/L","BASE2":2.78509,"BASE":2.8632,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05085,"PCHG2":1.8257,"CHG":-0.02726,"PCHG":-0.95206,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-16 12:51:08","ADY":226,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-25","SUBJID":"id-25","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.7821,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-11-02 12:51:08","TRTEDTM":"2022-02-16 10:48:14","TRT01SDTM":"2020-11-02 12:51:08","TRT01EDTM":"2021-02-16 04:48:14","TRT02SDTM":"2021-02-16 04:48:14","TRT02EDTM":"2022-02-16 10:48:14","AP01SDTM":"2020-11-02 12:51:08","AP01EDTM":"2021-02-16 04:48:14","AP02SDTM":"2021-02-16 04:48:14","AP02EDTM":"2022-02-16 10:48:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":471,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8025,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84582,"AVALU":"g/L","BASE2":2.78509,"BASE":2.8632,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06073,"PCHG2":2.18057,"CHG":-0.01738,"PCHG":-0.60687,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-26 12:51:08","ADY":389,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-25","SUBJID":"id-25","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.7821,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-11-02 12:51:08","TRTEDTM":"2022-02-16 10:48:14","TRT01SDTM":"2020-11-02 12:51:08","TRT01EDTM":"2021-02-16 04:48:14","TRT02SDTM":"2021-02-16 04:48:14","TRT02EDTM":"2022-02-16 10:48:14","AP01SDTM":"2020-11-02 12:51:08","AP01EDTM":"2021-02-16 04:48:14","AP02SDTM":"2021-02-16 04:48:14","AP02EDTM":"2022-02-16 10:48:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":471,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2497,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.028,"AVALU":"g/L","BASE2":2.78509,"BASE":2.8632,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.24291,"PCHG2":8.72193,"CHG":0.16481,"PCHG":5.75605,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-12-24 12:51:08","ADY":417,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-25","SUBJID":"id-25","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.7821,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-11-02 12:51:08","TRTEDTM":"2022-02-16 10:48:14","TRT01SDTM":"2020-11-02 12:51:08","TRT01EDTM":"2021-02-16 04:48:14","TRT02SDTM":"2021-02-16 04:48:14","TRT02EDTM":"2022-02-16 10:48:14","AP01SDTM":"2020-11-02 12:51:08","AP01EDTM":"2021-02-16 04:48:14","AP02SDTM":"2021-02-16 04:48:14","AP02EDTM":"2022-02-16 10:48:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":471,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-09","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5807,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9423,"AVALU":"g/L","BASE2":2.78509,"BASE":2.8632,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15721,"PCHG2":5.64466,"CHG":0.0791,"PCHG":2.76272,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-10 12:51:08","ADY":465,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-253","SUBJID":"id-253","SITEID":"CHN-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.93549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-25 12:06:16","TRTEDTM":"2023-10-26 06:06:16","TRT01SDTM":"2020-10-25 12:06:16","TRT01EDTM":"2022-10-26 00:06:16","TRT02SDTM":"2022-10-26 00:06:16","TRT02EDTM":"2023-10-26 06:06:16","AP01SDTM":"2020-10-25 12:06:16","AP01EDTM":"2022-10-26 00:06:16","AP02SDTM":"2022-10-26 00:06:16","AP02EDTM":"2023-10-26 06:06:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-26","EOSDY":1096,"LSTALVDT":"2023-11-21","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7276,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.3275,"AVALU":"U/L","BASE2":25.3275,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-22 12:06:16","ADY":209,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-253","SUBJID":"id-253","SITEID":"CHN-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.93549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-25 12:06:16","TRTEDTM":"2023-10-26 06:06:16","TRT01SDTM":"2020-10-25 12:06:16","TRT01EDTM":"2022-10-26 00:06:16","TRT02SDTM":"2022-10-26 00:06:16","TRT02EDTM":"2023-10-26 06:06:16","AP01SDTM":"2020-10-25 12:06:16","AP01EDTM":"2022-10-26 00:06:16","AP02SDTM":"2022-10-26 00:06:16","AP02EDTM":"2023-10-26 06:06:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-26","EOSDY":1096,"LSTALVDT":"2023-11-21","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2259,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.17392,"AVALU":"U/L","BASE2":25.3275,"BASE":13.17392,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-12.15358,"PCHG2":-47.98571,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-26 12:06:16","ADY":366,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-253","SUBJID":"id-253","SITEID":"CHN-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.93549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-25 12:06:16","TRTEDTM":"2023-10-26 06:06:16","TRT01SDTM":"2020-10-25 12:06:16","TRT01EDTM":"2022-10-26 00:06:16","TRT02SDTM":"2022-10-26 00:06:16","TRT02EDTM":"2023-10-26 06:06:16","AP01SDTM":"2020-10-25 12:06:16","AP01EDTM":"2022-10-26 00:06:16","AP02SDTM":"2022-10-26 00:06:16","AP02EDTM":"2023-10-26 06:06:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-26","EOSDY":1096,"LSTALVDT":"2023-11-21","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":416,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.36997,"AVALU":"U/L","BASE2":25.3275,"BASE":13.17392,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.95753,"PCHG2":-66.95303,"CHG":-4.80395,"PCHG":-36.4656,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-10 12:06:16","ADY":381,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-253","SUBJID":"id-253","SITEID":"CHN-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.93549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-25 12:06:16","TRTEDTM":"2023-10-26 06:06:16","TRT01SDTM":"2020-10-25 12:06:16","TRT01EDTM":"2022-10-26 00:06:16","TRT02SDTM":"2022-10-26 00:06:16","TRT02EDTM":"2023-10-26 06:06:16","AP01SDTM":"2020-10-25 12:06:16","AP01EDTM":"2022-10-26 00:06:16","AP02SDTM":"2022-10-26 00:06:16","AP02EDTM":"2023-10-26 06:06:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-26","EOSDY":1096,"LSTALVDT":"2023-11-21","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3930,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.11236,"AVALU":"U/L","BASE2":25.3275,"BASE":13.17392,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.21514,"PCHG2":-64.02185,"CHG":-4.06156,"PCHG":-30.83027,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-07 12:06:16","ADY":712,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-253","SUBJID":"id-253","SITEID":"CHN-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.93549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-25 12:06:16","TRTEDTM":"2023-10-26 06:06:16","TRT01SDTM":"2020-10-25 12:06:16","TRT01EDTM":"2022-10-26 00:06:16","TRT02SDTM":"2022-10-26 00:06:16","TRT02EDTM":"2023-10-26 06:06:16","AP01SDTM":"2020-10-25 12:06:16","AP01EDTM":"2022-10-26 00:06:16","AP02SDTM":"2022-10-26 00:06:16","AP02EDTM":"2023-10-26 06:06:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-26","EOSDY":1096,"LSTALVDT":"2023-11-21","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7326,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.15322,"AVALU":"U/L","BASE2":25.3275,"BASE":13.17392,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.17428,"PCHG2":-12.53293,"CHG":8.9793,"PCHG":68.15968,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-11 12:06:16","ADY":959,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-253","SUBJID":"id-253","SITEID":"CHN-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.93549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-25 12:06:16","TRTEDTM":"2023-10-26 06:06:16","TRT01SDTM":"2020-10-25 12:06:16","TRT01EDTM":"2022-10-26 00:06:16","TRT02SDTM":"2022-10-26 00:06:16","TRT02EDTM":"2023-10-26 06:06:16","AP01SDTM":"2020-10-25 12:06:16","AP01EDTM":"2022-10-26 00:06:16","AP02SDTM":"2022-10-26 00:06:16","AP02EDTM":"2023-10-26 06:06:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-26","EOSDY":1096,"LSTALVDT":"2023-11-21","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3951,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.82728,"AVALU":"U/L","BASE2":25.3275,"BASE":13.17392,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.49978,"PCHG2":5.92154,"CHG":13.65336,"PCHG":103.6393,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-26 12:06:16","ADY":974,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-253","SUBJID":"id-253","SITEID":"CHN-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.93549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-25 12:06:16","TRTEDTM":"2023-10-26 06:06:16","TRT01SDTM":"2020-10-25 12:06:16","TRT01EDTM":"2022-10-26 00:06:16","TRT02SDTM":"2022-10-26 00:06:16","TRT02EDTM":"2023-10-26 06:06:16","AP01SDTM":"2020-10-25 12:06:16","AP01EDTM":"2022-10-26 00:06:16","AP02SDTM":"2022-10-26 00:06:16","AP02EDTM":"2023-10-26 06:06:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-26","EOSDY":1096,"LSTALVDT":"2023-11-21","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2305,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.20073,"AVALU":"U/L","BASE2":25.3275,"BASE":13.17392,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.12677,"PCHG2":-39.98331,"CHG":2.02681,"PCHG":15.385,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-04 12:06:16","ADY":982,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-253","SUBJID":"id-253","SITEID":"CHN-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.93549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-25 12:06:16","TRTEDTM":"2023-10-26 06:06:16","TRT01SDTM":"2020-10-25 12:06:16","TRT01EDTM":"2022-10-26 00:06:16","TRT02SDTM":"2022-10-26 00:06:16","TRT02EDTM":"2023-10-26 06:06:16","AP01SDTM":"2020-10-25 12:06:16","AP01EDTM":"2022-10-26 00:06:16","AP02SDTM":"2022-10-26 00:06:16","AP02EDTM":"2023-10-26 06:06:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-26","EOSDY":1096,"LSTALVDT":"2023-11-21","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6401,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.92108,"AVALU":"mg/L","BASE2":7.92108,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"-4","BTOXGR":"2","ADTM":"2021-05-22 12:06:16","ADY":209,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-253","SUBJID":"id-253","SITEID":"CHN-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.93549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-25 12:06:16","TRTEDTM":"2023-10-26 06:06:16","TRT01SDTM":"2020-10-25 12:06:16","TRT01EDTM":"2022-10-26 00:06:16","TRT02SDTM":"2022-10-26 00:06:16","TRT02EDTM":"2023-10-26 06:06:16","AP01SDTM":"2020-10-25 12:06:16","AP01EDTM":"2022-10-26 00:06:16","AP02SDTM":"2022-10-26 00:06:16","AP02EDTM":"2023-10-26 06:06:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-26","EOSDY":1096,"LSTALVDT":"2023-11-21","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":960,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.53226,"AVALU":"mg/L","BASE2":7.92108,"BASE":10.53226,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.61118,"PCHG2":32.96495,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2021-10-26 12:06:16","ADY":366,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-253","SUBJID":"id-253","SITEID":"CHN-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.93549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-25 12:06:16","TRTEDTM":"2023-10-26 06:06:16","TRT01SDTM":"2020-10-25 12:06:16","TRT01EDTM":"2022-10-26 00:06:16","TRT02SDTM":"2022-10-26 00:06:16","TRT02EDTM":"2023-10-26 06:06:16","AP01SDTM":"2020-10-25 12:06:16","AP01EDTM":"2022-10-26 00:06:16","AP02SDTM":"2022-10-26 00:06:16","AP02EDTM":"2023-10-26 06:06:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-26","EOSDY":1096,"LSTALVDT":"2023-11-21","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1154,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.491,"AVALU":"mg/L","BASE2":7.92108,"BASE":10.53226,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.56992,"PCHG2":19.81955,"CHG":-1.04126,"PCHG":-9.88636,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-11-10 12:06:16","ADY":381,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-253","SUBJID":"id-253","SITEID":"CHN-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.93549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-25 12:06:16","TRTEDTM":"2023-10-26 06:06:16","TRT01SDTM":"2020-10-25 12:06:16","TRT01EDTM":"2022-10-26 00:06:16","TRT02SDTM":"2022-10-26 00:06:16","TRT02EDTM":"2023-10-26 06:06:16","AP01SDTM":"2020-10-25 12:06:16","AP01EDTM":"2022-10-26 00:06:16","AP02SDTM":"2022-10-26 00:06:16","AP02EDTM":"2023-10-26 06:06:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-26","EOSDY":1096,"LSTALVDT":"2023-11-21","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1448,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.40904,"AVALU":"mg/L","BASE2":7.92108,"BASE":10.53226,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.48796,"PCHG2":18.78476,"CHG":-1.12322,"PCHG":-10.66461,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-10-07 12:06:16","ADY":712,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-253","SUBJID":"id-253","SITEID":"CHN-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.93549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-25 12:06:16","TRTEDTM":"2023-10-26 06:06:16","TRT01SDTM":"2020-10-25 12:06:16","TRT01EDTM":"2022-10-26 00:06:16","TRT02SDTM":"2022-10-26 00:06:16","TRT02EDTM":"2023-10-26 06:06:16","AP01SDTM":"2020-10-25 12:06:16","AP01EDTM":"2022-10-26 00:06:16","AP02SDTM":"2022-10-26 00:06:16","AP02EDTM":"2023-10-26 06:06:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-26","EOSDY":1096,"LSTALVDT":"2023-11-21","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":584,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.50857,"AVALU":"mg/L","BASE2":7.92108,"BASE":10.53226,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.58749,"PCHG2":7.41683,"CHG":-2.02369,"PCHG":-19.21418,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2023-06-11 12:06:16","ADY":959,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-253","SUBJID":"id-253","SITEID":"CHN-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.93549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-25 12:06:16","TRTEDTM":"2023-10-26 06:06:16","TRT01SDTM":"2020-10-25 12:06:16","TRT01EDTM":"2022-10-26 00:06:16","TRT02SDTM":"2022-10-26 00:06:16","TRT02EDTM":"2023-10-26 06:06:16","AP01SDTM":"2020-10-25 12:06:16","AP01EDTM":"2022-10-26 00:06:16","AP02SDTM":"2022-10-26 00:06:16","AP02EDTM":"2023-10-26 06:06:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-26","EOSDY":1096,"LSTALVDT":"2023-11-21","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4164,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.34152,"AVALU":"mg/L","BASE2":7.92108,"BASE":10.53226,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.42044,"PCHG2":5.30786,"CHG":-2.19074,"PCHG":-20.80029,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2023-06-26 12:06:16","ADY":974,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-253","SUBJID":"id-253","SITEID":"CHN-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.93549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-25 12:06:16","TRTEDTM":"2023-10-26 06:06:16","TRT01SDTM":"2020-10-25 12:06:16","TRT01EDTM":"2022-10-26 00:06:16","TRT02SDTM":"2022-10-26 00:06:16","TRT02EDTM":"2023-10-26 06:06:16","AP01SDTM":"2020-10-25 12:06:16","AP01EDTM":"2022-10-26 00:06:16","AP02SDTM":"2022-10-26 00:06:16","AP02EDTM":"2023-10-26 06:06:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-26","EOSDY":1096,"LSTALVDT":"2023-11-21","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1869,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.82312,"AVALU":"mg/L","BASE2":7.92108,"BASE":10.53226,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.90204,"PCHG2":24.01236,"CHG":-0.70914,"PCHG":-6.73304,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2023-07-04 12:06:16","ADY":982,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-253","SUBJID":"id-253","SITEID":"CHN-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.93549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-25 12:06:16","TRTEDTM":"2023-10-26 06:06:16","TRT01SDTM":"2020-10-25 12:06:16","TRT01EDTM":"2022-10-26 00:06:16","TRT02SDTM":"2022-10-26 00:06:16","TRT02EDTM":"2023-10-26 06:06:16","AP01SDTM":"2020-10-25 12:06:16","AP01EDTM":"2022-10-26 00:06:16","AP02SDTM":"2022-10-26 00:06:16","AP02EDTM":"2023-10-26 06:06:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-26","EOSDY":1096,"LSTALVDT":"2023-11-21","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4057,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9851,"AVALU":"g/L","BASE2":2.9851,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-22 12:06:16","ADY":209,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-253","SUBJID":"id-253","SITEID":"CHN-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.93549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-25 12:06:16","TRTEDTM":"2023-10-26 06:06:16","TRT01SDTM":"2020-10-25 12:06:16","TRT01EDTM":"2022-10-26 00:06:16","TRT02SDTM":"2022-10-26 00:06:16","TRT02EDTM":"2023-10-26 06:06:16","AP01SDTM":"2020-10-25 12:06:16","AP01EDTM":"2022-10-26 00:06:16","AP02SDTM":"2022-10-26 00:06:16","AP02EDTM":"2023-10-26 06:06:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-26","EOSDY":1096,"LSTALVDT":"2023-11-21","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":396,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.71925,"AVALU":"g/L","BASE2":2.9851,"BASE":2.71925,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.26586,"PCHG2":-8.90615,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-26 12:06:16","ADY":366,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-253","SUBJID":"id-253","SITEID":"CHN-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.93549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-25 12:06:16","TRTEDTM":"2023-10-26 06:06:16","TRT01SDTM":"2020-10-25 12:06:16","TRT01EDTM":"2022-10-26 00:06:16","TRT02SDTM":"2022-10-26 00:06:16","TRT02EDTM":"2023-10-26 06:06:16","AP01SDTM":"2020-10-25 12:06:16","AP01EDTM":"2022-10-26 00:06:16","AP02SDTM":"2022-10-26 00:06:16","AP02EDTM":"2023-10-26 06:06:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-26","EOSDY":1096,"LSTALVDT":"2023-11-21","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":637,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8907,"AVALU":"g/L","BASE2":2.9851,"BASE":2.71925,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0944,"PCHG2":-3.16236,"CHG":0.17146,"PCHG":6.30535,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-10 12:06:16","ADY":381,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-253","SUBJID":"id-253","SITEID":"CHN-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.93549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-25 12:06:16","TRTEDTM":"2023-10-26 06:06:16","TRT01SDTM":"2020-10-25 12:06:16","TRT01EDTM":"2022-10-26 00:06:16","TRT02SDTM":"2022-10-26 00:06:16","TRT02EDTM":"2023-10-26 06:06:16","AP01SDTM":"2020-10-25 12:06:16","AP01EDTM":"2022-10-26 00:06:16","AP02SDTM":"2022-10-26 00:06:16","AP02EDTM":"2023-10-26 06:06:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-26","EOSDY":1096,"LSTALVDT":"2023-11-21","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5280,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97041,"AVALU":"g/L","BASE2":2.9851,"BASE":2.71925,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01469,"PCHG2":-0.49211,"CHG":0.25117,"PCHG":9.23667,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-07 12:06:16","ADY":712,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-253","SUBJID":"id-253","SITEID":"CHN-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.93549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-25 12:06:16","TRTEDTM":"2023-10-26 06:06:16","TRT01SDTM":"2020-10-25 12:06:16","TRT01EDTM":"2022-10-26 00:06:16","TRT02SDTM":"2022-10-26 00:06:16","TRT02EDTM":"2023-10-26 06:06:16","AP01SDTM":"2020-10-25 12:06:16","AP01EDTM":"2022-10-26 00:06:16","AP02SDTM":"2022-10-26 00:06:16","AP02EDTM":"2023-10-26 06:06:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-26","EOSDY":1096,"LSTALVDT":"2023-11-21","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1015,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99631,"AVALU":"g/L","BASE2":2.9851,"BASE":2.71925,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01121,"PCHG2":0.37537,"CHG":0.27706,"PCHG":10.18896,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-11 12:06:16","ADY":959,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-253","SUBJID":"id-253","SITEID":"CHN-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.93549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-25 12:06:16","TRTEDTM":"2023-10-26 06:06:16","TRT01SDTM":"2020-10-25 12:06:16","TRT01EDTM":"2022-10-26 00:06:16","TRT02SDTM":"2022-10-26 00:06:16","TRT02EDTM":"2023-10-26 06:06:16","AP01SDTM":"2020-10-25 12:06:16","AP01EDTM":"2022-10-26 00:06:16","AP02SDTM":"2022-10-26 00:06:16","AP02EDTM":"2023-10-26 06:06:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-26","EOSDY":1096,"LSTALVDT":"2023-11-21","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6895,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84199,"AVALU":"g/L","BASE2":2.9851,"BASE":2.71925,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14311,"PCHG2":-4.79428,"CHG":0.12274,"PCHG":4.51388,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-26 12:06:16","ADY":974,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-253","SUBJID":"id-253","SITEID":"CHN-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.93549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-25 12:06:16","TRTEDTM":"2023-10-26 06:06:16","TRT01SDTM":"2020-10-25 12:06:16","TRT01EDTM":"2022-10-26 00:06:16","TRT02SDTM":"2022-10-26 00:06:16","TRT02EDTM":"2023-10-26 06:06:16","AP01SDTM":"2020-10-25 12:06:16","AP01EDTM":"2022-10-26 00:06:16","AP02SDTM":"2022-10-26 00:06:16","AP02EDTM":"2023-10-26 06:06:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-26","EOSDY":1096,"LSTALVDT":"2023-11-21","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7536,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94539,"AVALU":"g/L","BASE2":2.9851,"BASE":2.71925,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03972,"PCHG2":-1.33055,"CHG":0.22614,"PCHG":8.31625,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-04 12:06:16","ADY":982,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-26","SUBJID":"id-26","SITEID":"CHN-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.07407,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-07-12","TRTSDTM":"2020-07-16 12:27:24","TRTEDTM":"2023-07-17 06:27:24","TRT01SDTM":"2020-07-16 12:27:24","TRT01EDTM":"2022-07-17 00:27:24","TRT02SDTM":"2022-07-17 00:27:24","TRT02EDTM":"2023-07-17 06:27:24","AP01SDTM":"2020-07-16 12:27:24","AP01EDTM":"2022-07-17 00:27:24","AP02SDTM":"2022-07-17 00:27:24","AP02EDTM":"2023-07-17 06:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7999,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.19804,"AVALU":"U/L","BASE2":27.19804,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-26 12:27:24","ADY":10,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-26","SUBJID":"id-26","SITEID":"CHN-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.07407,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-07-12","TRTSDTM":"2020-07-16 12:27:24","TRTEDTM":"2023-07-17 06:27:24","TRT01SDTM":"2020-07-16 12:27:24","TRT01EDTM":"2022-07-17 00:27:24","TRT02SDTM":"2022-07-17 00:27:24","TRT02EDTM":"2023-07-17 06:27:24","AP01SDTM":"2020-07-16 12:27:24","AP01EDTM":"2022-07-17 00:27:24","AP02SDTM":"2022-07-17 00:27:24","AP02EDTM":"2023-07-17 06:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3301,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.15406,"AVALU":"U/L","BASE2":27.19804,"BASE":15.15406,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-12.04397,"PCHG2":-44.28251,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-23 12:27:24","ADY":38,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-26","SUBJID":"id-26","SITEID":"CHN-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.07407,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-07-12","TRTSDTM":"2020-07-16 12:27:24","TRTEDTM":"2023-07-17 06:27:24","TRT01SDTM":"2020-07-16 12:27:24","TRT01EDTM":"2022-07-17 00:27:24","TRT02SDTM":"2022-07-17 00:27:24","TRT02EDTM":"2023-07-17 06:27:24","AP01SDTM":"2020-07-16 12:27:24","AP01EDTM":"2022-07-17 00:27:24","AP02SDTM":"2022-07-17 00:27:24","AP02EDTM":"2023-07-17 06:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5464,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.07334,"AVALU":"U/L","BASE2":27.19804,"BASE":15.15406,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-18.1247,"PCHG2":-66.63974,"CHG":-6.08073,"PCHG":-40.12605,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-19 12:27:24","ADY":338,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-26","SUBJID":"id-26","SITEID":"CHN-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.07407,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-07-12","TRTSDTM":"2020-07-16 12:27:24","TRTEDTM":"2023-07-17 06:27:24","TRT01SDTM":"2020-07-16 12:27:24","TRT01EDTM":"2022-07-17 00:27:24","TRT02SDTM":"2022-07-17 00:27:24","TRT02EDTM":"2023-07-17 06:27:24","AP01SDTM":"2020-07-16 12:27:24","AP01EDTM":"2022-07-17 00:27:24","AP02SDTM":"2022-07-17 00:27:24","AP02EDTM":"2023-07-17 06:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6412,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.9463,"AVALU":"U/L","BASE2":27.19804,"BASE":15.15406,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.25173,"PCHG2":-8.27903,"CHG":9.79224,"PCHG":64.61792,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-25 12:27:24","ADY":617,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-26","SUBJID":"id-26","SITEID":"CHN-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.07407,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-07-12","TRTSDTM":"2020-07-16 12:27:24","TRTEDTM":"2023-07-17 06:27:24","TRT01SDTM":"2020-07-16 12:27:24","TRT01EDTM":"2022-07-17 00:27:24","TRT02SDTM":"2022-07-17 00:27:24","TRT02EDTM":"2023-07-17 06:27:24","AP01SDTM":"2020-07-16 12:27:24","AP01EDTM":"2022-07-17 00:27:24","AP02SDTM":"2022-07-17 00:27:24","AP02EDTM":"2023-07-17 06:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2455,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.84793,"AVALU":"U/L","BASE2":27.19804,"BASE":15.15406,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.35011,"PCHG2":-4.964,"CHG":10.69386,"PCHG":70.56763,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-26 12:27:24","ADY":710,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-26","SUBJID":"id-26","SITEID":"CHN-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.07407,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-07-12","TRTSDTM":"2020-07-16 12:27:24","TRTEDTM":"2023-07-17 06:27:24","TRT01SDTM":"2020-07-16 12:27:24","TRT01EDTM":"2022-07-17 00:27:24","TRT02SDTM":"2022-07-17 00:27:24","TRT02EDTM":"2023-07-17 06:27:24","AP01SDTM":"2020-07-16 12:27:24","AP01EDTM":"2022-07-17 00:27:24","AP02SDTM":"2022-07-17 00:27:24","AP02EDTM":"2023-07-17 06:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6383,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.10861,"AVALU":"U/L","BASE2":27.19804,"BASE":15.15406,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-26.08943,"PCHG2":-95.92393,"CHG":-14.04545,"PCHG":-92.68441,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2023-01-07 12:27:24","ADY":905,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-26","SUBJID":"id-26","SITEID":"CHN-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.07407,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-07-12","TRTSDTM":"2020-07-16 12:27:24","TRTEDTM":"2023-07-17 06:27:24","TRT01SDTM":"2020-07-16 12:27:24","TRT01EDTM":"2022-07-17 00:27:24","TRT02SDTM":"2022-07-17 00:27:24","TRT02EDTM":"2023-07-17 06:27:24","AP01SDTM":"2020-07-16 12:27:24","AP01EDTM":"2022-07-17 00:27:24","AP02SDTM":"2022-07-17 00:27:24","AP02EDTM":"2023-07-17 06:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4590,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.21653,"AVALU":"U/L","BASE2":27.19804,"BASE":15.15406,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.98151,"PCHG2":-33.02265,"CHG":3.06246,"PCHG":20.20885,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-26 12:27:24","ADY":924,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-26","SUBJID":"id-26","SITEID":"CHN-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.07407,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-07-12","TRTSDTM":"2020-07-16 12:27:24","TRTEDTM":"2023-07-17 06:27:24","TRT01SDTM":"2020-07-16 12:27:24","TRT01EDTM":"2022-07-17 00:27:24","TRT02SDTM":"2022-07-17 00:27:24","TRT02EDTM":"2023-07-17 06:27:24","AP01SDTM":"2020-07-16 12:27:24","AP01EDTM":"2022-07-17 00:27:24","AP02SDTM":"2022-07-17 00:27:24","AP02EDTM":"2023-07-17 06:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6921,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.77805,"AVALU":"mg/L","BASE2":8.77805,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-07-26 12:27:24","ADY":10,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-26","SUBJID":"id-26","SITEID":"CHN-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.07407,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-07-12","TRTSDTM":"2020-07-16 12:27:24","TRTEDTM":"2023-07-17 06:27:24","TRT01SDTM":"2020-07-16 12:27:24","TRT01EDTM":"2022-07-17 00:27:24","TRT02SDTM":"2022-07-17 00:27:24","TRT02EDTM":"2023-07-17 06:27:24","AP01SDTM":"2020-07-16 12:27:24","AP01EDTM":"2022-07-17 00:27:24","AP02SDTM":"2022-07-17 00:27:24","AP02EDTM":"2023-07-17 06:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3225,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.90827,"AVALU":"mg/L","BASE2":8.77805,"BASE":7.90827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.86978,"PCHG2":-9.90856,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2020-08-23 12:27:24","ADY":38,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-26","SUBJID":"id-26","SITEID":"CHN-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.07407,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-07-12","TRTSDTM":"2020-07-16 12:27:24","TRTEDTM":"2023-07-17 06:27:24","TRT01SDTM":"2020-07-16 12:27:24","TRT01EDTM":"2022-07-17 00:27:24","TRT02SDTM":"2022-07-17 00:27:24","TRT02EDTM":"2023-07-17 06:27:24","AP01SDTM":"2020-07-16 12:27:24","AP01EDTM":"2022-07-17 00:27:24","AP02SDTM":"2022-07-17 00:27:24","AP02EDTM":"2023-07-17 06:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8385,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.10011,"AVALU":"mg/L","BASE2":8.77805,"BASE":7.90827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.67794,"PCHG2":-19.11516,"CHG":-0.80816,"PCHG":-10.21917,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-4","BTOXGR":"-2","ADTM":"2021-06-19 12:27:24","ADY":338,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-26","SUBJID":"id-26","SITEID":"CHN-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.07407,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-07-12","TRTSDTM":"2020-07-16 12:27:24","TRTEDTM":"2023-07-17 06:27:24","TRT01SDTM":"2020-07-16 12:27:24","TRT01EDTM":"2022-07-17 00:27:24","TRT02SDTM":"2022-07-17 00:27:24","TRT02EDTM":"2023-07-17 06:27:24","AP01SDTM":"2020-07-16 12:27:24","AP01EDTM":"2022-07-17 00:27:24","AP02SDTM":"2022-07-17 00:27:24","AP02EDTM":"2023-07-17 06:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":601,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.98444,"AVALU":"mg/L","BASE2":8.77805,"BASE":7.90827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.20639,"PCHG2":13.74328,"CHG":2.07617,"PCHG":26.25316,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-03-25 12:27:24","ADY":617,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-26","SUBJID":"id-26","SITEID":"CHN-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.07407,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-07-12","TRTSDTM":"2020-07-16 12:27:24","TRTEDTM":"2023-07-17 06:27:24","TRT01SDTM":"2020-07-16 12:27:24","TRT01EDTM":"2022-07-17 00:27:24","TRT02SDTM":"2022-07-17 00:27:24","TRT02EDTM":"2023-07-17 06:27:24","AP01SDTM":"2020-07-16 12:27:24","AP01EDTM":"2022-07-17 00:27:24","AP02SDTM":"2022-07-17 00:27:24","AP02EDTM":"2023-07-17 06:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7964,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.68832,"AVALU":"mg/L","BASE2":8.77805,"BASE":7.90827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.91027,"PCHG2":10.36983,"CHG":1.78005,"PCHG":22.50868,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-06-26 12:27:24","ADY":710,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-26","SUBJID":"id-26","SITEID":"CHN-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.07407,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-07-12","TRTSDTM":"2020-07-16 12:27:24","TRTEDTM":"2023-07-17 06:27:24","TRT01SDTM":"2020-07-16 12:27:24","TRT01EDTM":"2022-07-17 00:27:24","TRT02SDTM":"2022-07-17 00:27:24","TRT02EDTM":"2023-07-17 06:27:24","AP01SDTM":"2020-07-16 12:27:24","AP01EDTM":"2022-07-17 00:27:24","AP02SDTM":"2022-07-17 00:27:24","AP02EDTM":"2023-07-17 06:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3079,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.63219,"AVALU":"mg/L","BASE2":8.77805,"BASE":7.90827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.85414,"PCHG2":21.1225,"CHG":2.72392,"PCHG":34.44396,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"3","BTOXGR":"-2","ADTM":"2023-01-07 12:27:24","ADY":905,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-26","SUBJID":"id-26","SITEID":"CHN-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.07407,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-07-12","TRTSDTM":"2020-07-16 12:27:24","TRTEDTM":"2023-07-17 06:27:24","TRT01SDTM":"2020-07-16 12:27:24","TRT01EDTM":"2022-07-17 00:27:24","TRT02SDTM":"2022-07-17 00:27:24","TRT02EDTM":"2023-07-17 06:27:24","AP01SDTM":"2020-07-16 12:27:24","AP01EDTM":"2022-07-17 00:27:24","AP02SDTM":"2022-07-17 00:27:24","AP02EDTM":"2023-07-17 06:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5225,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.09069,"AVALU":"mg/L","BASE2":8.77805,"BASE":7.90827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.31264,"PCHG2":26.34569,"CHG":3.18242,"PCHG":40.24162,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"1","BTOXGR":"-2","ADTM":"2023-01-26 12:27:24","ADY":924,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-26","SUBJID":"id-26","SITEID":"CHN-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.07407,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-07-12","TRTSDTM":"2020-07-16 12:27:24","TRTEDTM":"2023-07-17 06:27:24","TRT01SDTM":"2020-07-16 12:27:24","TRT01EDTM":"2022-07-17 00:27:24","TRT02SDTM":"2022-07-17 00:27:24","TRT02EDTM":"2023-07-17 06:27:24","AP01SDTM":"2020-07-16 12:27:24","AP01EDTM":"2022-07-17 00:27:24","AP02SDTM":"2022-07-17 00:27:24","AP02EDTM":"2023-07-17 06:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":554,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.72411,"AVALU":"g/L","BASE2":2.72411,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-26 12:27:24","ADY":10,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-26","SUBJID":"id-26","SITEID":"CHN-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.07407,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-07-12","TRTSDTM":"2020-07-16 12:27:24","TRTEDTM":"2023-07-17 06:27:24","TRT01SDTM":"2020-07-16 12:27:24","TRT01EDTM":"2022-07-17 00:27:24","TRT02SDTM":"2022-07-17 00:27:24","TRT02EDTM":"2023-07-17 06:27:24","AP01SDTM":"2020-07-16 12:27:24","AP01EDTM":"2022-07-17 00:27:24","AP02SDTM":"2022-07-17 00:27:24","AP02EDTM":"2023-07-17 06:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6336,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92176,"AVALU":"g/L","BASE2":2.72411,"BASE":2.92176,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.19765,"PCHG2":7.25551,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-23 12:27:24","ADY":38,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-26","SUBJID":"id-26","SITEID":"CHN-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.07407,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-07-12","TRTSDTM":"2020-07-16 12:27:24","TRTEDTM":"2023-07-17 06:27:24","TRT01SDTM":"2020-07-16 12:27:24","TRT01EDTM":"2022-07-17 00:27:24","TRT02SDTM":"2022-07-17 00:27:24","TRT02EDTM":"2023-07-17 06:27:24","AP01SDTM":"2020-07-16 12:27:24","AP01EDTM":"2022-07-17 00:27:24","AP02SDTM":"2022-07-17 00:27:24","AP02EDTM":"2023-07-17 06:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6398,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8978,"AVALU":"g/L","BASE2":2.72411,"BASE":2.92176,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17369,"PCHG2":6.37619,"CHG":-0.02395,"PCHG":-0.81984,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-19 12:27:24","ADY":338,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-26","SUBJID":"id-26","SITEID":"CHN-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.07407,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-07-12","TRTSDTM":"2020-07-16 12:27:24","TRTEDTM":"2023-07-17 06:27:24","TRT01SDTM":"2020-07-16 12:27:24","TRT01EDTM":"2022-07-17 00:27:24","TRT02SDTM":"2022-07-17 00:27:24","TRT02EDTM":"2023-07-17 06:27:24","AP01SDTM":"2020-07-16 12:27:24","AP01EDTM":"2022-07-17 00:27:24","AP02SDTM":"2022-07-17 00:27:24","AP02EDTM":"2023-07-17 06:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6417,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.943,"AVALU":"g/L","BASE2":2.72411,"BASE":2.92176,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.21889,"PCHG2":8.03518,"CHG":0.02124,"PCHG":0.72693,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-25 12:27:24","ADY":617,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-26","SUBJID":"id-26","SITEID":"CHN-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.07407,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-07-12","TRTSDTM":"2020-07-16 12:27:24","TRTEDTM":"2023-07-17 06:27:24","TRT01SDTM":"2020-07-16 12:27:24","TRT01EDTM":"2022-07-17 00:27:24","TRT02SDTM":"2022-07-17 00:27:24","TRT02EDTM":"2023-07-17 06:27:24","AP01SDTM":"2020-07-16 12:27:24","AP01EDTM":"2022-07-17 00:27:24","AP02SDTM":"2022-07-17 00:27:24","AP02EDTM":"2023-07-17 06:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6479,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77272,"AVALU":"g/L","BASE2":2.72411,"BASE":2.92176,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04861,"PCHG2":1.78462,"CHG":-0.14903,"PCHG":-5.10081,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-26 12:27:24","ADY":710,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-26","SUBJID":"id-26","SITEID":"CHN-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.07407,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-07-12","TRTSDTM":"2020-07-16 12:27:24","TRTEDTM":"2023-07-17 06:27:24","TRT01SDTM":"2020-07-16 12:27:24","TRT01EDTM":"2022-07-17 00:27:24","TRT02SDTM":"2022-07-17 00:27:24","TRT02EDTM":"2023-07-17 06:27:24","AP01SDTM":"2020-07-16 12:27:24","AP01EDTM":"2022-07-17 00:27:24","AP02SDTM":"2022-07-17 00:27:24","AP02EDTM":"2023-07-17 06:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3693,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91252,"AVALU":"g/L","BASE2":2.72411,"BASE":2.92176,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18841,"PCHG2":6.91631,"CHG":-0.00924,"PCHG":-0.31625,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-07 12:27:24","ADY":905,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-26","SUBJID":"id-26","SITEID":"CHN-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.07407,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-07-12","TRTSDTM":"2020-07-16 12:27:24","TRTEDTM":"2023-07-17 06:27:24","TRT01SDTM":"2020-07-16 12:27:24","TRT01EDTM":"2022-07-17 00:27:24","TRT02SDTM":"2022-07-17 00:27:24","TRT02EDTM":"2023-07-17 06:27:24","AP01SDTM":"2020-07-16 12:27:24","AP01EDTM":"2022-07-17 00:27:24","AP02SDTM":"2022-07-17 00:27:24","AP02EDTM":"2023-07-17 06:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6697,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97745,"AVALU":"g/L","BASE2":2.72411,"BASE":2.92176,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.25334,"PCHG2":9.29985,"CHG":0.05569,"PCHG":1.90605,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-26 12:27:24","ADY":924,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-275","SUBJID":"id-275","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.14151,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-01","TRTSDTM":"2020-06-02 23:28:44","TRTEDTM":"2023-06-03 17:28:44","TRT01SDTM":"2020-06-02 23:28:44","TRT01EDTM":"2022-06-03 11:28:44","TRT02SDTM":"2022-06-03 11:28:44","TRT02EDTM":"2023-06-03 17:28:44","AP01SDTM":"2020-06-02 23:28:44","AP01EDTM":"2022-06-03 11:28:44","AP02SDTM":"2022-06-03 11:28:44","AP02EDTM":"2023-06-03 17:28:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-03","EOSDY":1096,"LSTALVDT":"2023-06-22","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":707,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.5741,"AVALU":"U/L","BASE2":26.5741,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-14 23:28:44","ADY":12,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-275","SUBJID":"id-275","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.14151,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-01","TRTSDTM":"2020-06-02 23:28:44","TRTEDTM":"2023-06-03 17:28:44","TRT01SDTM":"2020-06-02 23:28:44","TRT01EDTM":"2022-06-03 11:28:44","TRT02SDTM":"2022-06-03 11:28:44","TRT02EDTM":"2023-06-03 17:28:44","AP01SDTM":"2020-06-02 23:28:44","AP01EDTM":"2022-06-03 11:28:44","AP02SDTM":"2022-06-03 11:28:44","AP02EDTM":"2023-06-03 17:28:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-03","EOSDY":1096,"LSTALVDT":"2023-06-22","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1332,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.56752,"AVALU":"U/L","BASE2":26.5741,"BASE":10.56752,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-16.00657,"PCHG2":-60.23375,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-17 23:28:44","ADY":260,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-275","SUBJID":"id-275","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.14151,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-01","TRTSDTM":"2020-06-02 23:28:44","TRTEDTM":"2023-06-03 17:28:44","TRT01SDTM":"2020-06-02 23:28:44","TRT01EDTM":"2022-06-03 11:28:44","TRT02SDTM":"2022-06-03 11:28:44","TRT02EDTM":"2023-06-03 17:28:44","AP01SDTM":"2020-06-02 23:28:44","AP01EDTM":"2022-06-03 11:28:44","AP02SDTM":"2022-06-03 11:28:44","AP02EDTM":"2023-06-03 17:28:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-03","EOSDY":1096,"LSTALVDT":"2023-06-22","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5268,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.08055,"AVALU":"U/L","BASE2":26.5741,"BASE":10.56752,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-21.49355,"PCHG2":-80.88157,"CHG":-5.48697,"PCHG":-51.92299,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-06-01 23:28:44","ADY":364,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-275","SUBJID":"id-275","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.14151,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-01","TRTSDTM":"2020-06-02 23:28:44","TRTEDTM":"2023-06-03 17:28:44","TRT01SDTM":"2020-06-02 23:28:44","TRT01EDTM":"2022-06-03 11:28:44","TRT02SDTM":"2022-06-03 11:28:44","TRT02EDTM":"2023-06-03 17:28:44","AP01SDTM":"2020-06-02 23:28:44","AP01EDTM":"2022-06-03 11:28:44","AP02SDTM":"2022-06-03 11:28:44","AP02EDTM":"2023-06-03 17:28:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-03","EOSDY":1096,"LSTALVDT":"2023-06-22","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1231,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.3058,"AVALU":"U/L","BASE2":26.5741,"BASE":10.56752,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.7317,"PCHG2":6.51651,"CHG":17.73828,"PCHG":167.85654,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-03 23:28:44","ADY":519,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-275","SUBJID":"id-275","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.14151,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-01","TRTSDTM":"2020-06-02 23:28:44","TRTEDTM":"2023-06-03 17:28:44","TRT01SDTM":"2020-06-02 23:28:44","TRT01EDTM":"2022-06-03 11:28:44","TRT02SDTM":"2022-06-03 11:28:44","TRT02EDTM":"2023-06-03 17:28:44","AP01SDTM":"2020-06-02 23:28:44","AP01EDTM":"2022-06-03 11:28:44","AP02SDTM":"2022-06-03 11:28:44","AP02EDTM":"2023-06-03 17:28:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-03","EOSDY":1096,"LSTALVDT":"2023-06-22","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7330,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.16835,"AVALU":"U/L","BASE2":26.5741,"BASE":10.56752,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.40575,"PCHG2":-61.73587,"CHG":-0.39918,"PCHG":-3.77738,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-16 23:28:44","ADY":593,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-275","SUBJID":"id-275","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.14151,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-01","TRTSDTM":"2020-06-02 23:28:44","TRTEDTM":"2023-06-03 17:28:44","TRT01SDTM":"2020-06-02 23:28:44","TRT01EDTM":"2022-06-03 11:28:44","TRT02SDTM":"2022-06-03 11:28:44","TRT02EDTM":"2023-06-03 17:28:44","AP01SDTM":"2020-06-02 23:28:44","AP01EDTM":"2022-06-03 11:28:44","AP02SDTM":"2022-06-03 11:28:44","AP02EDTM":"2023-06-03 17:28:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-03","EOSDY":1096,"LSTALVDT":"2023-06-22","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5227,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.01955,"AVALU":"U/L","BASE2":26.5741,"BASE":10.56752,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.55455,"PCHG2":-43.4805,"CHG":4.45203,"PCHG":42.12931,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-24 23:28:44","ADY":844,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-275","SUBJID":"id-275","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.14151,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-01","TRTSDTM":"2020-06-02 23:28:44","TRTEDTM":"2023-06-03 17:28:44","TRT01SDTM":"2020-06-02 23:28:44","TRT01EDTM":"2022-06-03 11:28:44","TRT02SDTM":"2022-06-03 11:28:44","TRT02EDTM":"2023-06-03 17:28:44","AP01SDTM":"2020-06-02 23:28:44","AP01EDTM":"2022-06-03 11:28:44","AP02SDTM":"2022-06-03 11:28:44","AP02EDTM":"2023-06-03 17:28:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-03","EOSDY":1096,"LSTALVDT":"2023-06-22","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7152,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.6471,"AVALU":"U/L","BASE2":26.5741,"BASE":10.56752,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.073,"PCHG2":4.03778,"CHG":17.07958,"PCHG":161.62328,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-01 23:28:44","ADY":1033,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-275","SUBJID":"id-275","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.14151,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-01","TRTSDTM":"2020-06-02 23:28:44","TRTEDTM":"2023-06-03 17:28:44","TRT01SDTM":"2020-06-02 23:28:44","TRT01EDTM":"2022-06-03 11:28:44","TRT02SDTM":"2022-06-03 11:28:44","TRT02EDTM":"2023-06-03 17:28:44","AP01SDTM":"2020-06-02 23:28:44","AP01EDTM":"2022-06-03 11:28:44","AP02SDTM":"2022-06-03 11:28:44","AP02EDTM":"2023-06-03 17:28:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-03","EOSDY":1096,"LSTALVDT":"2023-06-22","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2990,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.63589,"AVALU":"mg/L","BASE2":7.63589,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"-3","BTOXGR":"3","ADTM":"2020-06-14 23:28:44","ADY":12,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-275","SUBJID":"id-275","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.14151,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-01","TRTSDTM":"2020-06-02 23:28:44","TRTEDTM":"2023-06-03 17:28:44","TRT01SDTM":"2020-06-02 23:28:44","TRT01EDTM":"2022-06-03 11:28:44","TRT02SDTM":"2022-06-03 11:28:44","TRT02EDTM":"2023-06-03 17:28:44","AP01SDTM":"2020-06-02 23:28:44","AP01EDTM":"2022-06-03 11:28:44","AP02SDTM":"2022-06-03 11:28:44","AP02EDTM":"2023-06-03 17:28:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-03","EOSDY":1096,"LSTALVDT":"2023-06-22","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7113,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.13732,"AVALU":"mg/L","BASE2":7.63589,"BASE":10.13732,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.50143,"PCHG2":32.75888,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2021-02-17 23:28:44","ADY":260,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-275","SUBJID":"id-275","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.14151,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-01","TRTSDTM":"2020-06-02 23:28:44","TRTEDTM":"2023-06-03 17:28:44","TRT01SDTM":"2020-06-02 23:28:44","TRT01EDTM":"2022-06-03 11:28:44","TRT02SDTM":"2022-06-03 11:28:44","TRT02EDTM":"2023-06-03 17:28:44","AP01SDTM":"2020-06-02 23:28:44","AP01EDTM":"2022-06-03 11:28:44","AP02SDTM":"2022-06-03 11:28:44","AP02EDTM":"2023-06-03 17:28:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-03","EOSDY":1096,"LSTALVDT":"2023-06-22","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2523,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.75275,"AVALU":"mg/L","BASE2":7.63589,"BASE":10.13732,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.88313,"PCHG2":-11.56558,"CHG":-3.38457,"PCHG":-33.38719,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-2","BTOXGR":"3","ADTM":"2021-06-01 23:28:44","ADY":364,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-275","SUBJID":"id-275","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.14151,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-01","TRTSDTM":"2020-06-02 23:28:44","TRTEDTM":"2023-06-03 17:28:44","TRT01SDTM":"2020-06-02 23:28:44","TRT01EDTM":"2022-06-03 11:28:44","TRT02SDTM":"2022-06-03 11:28:44","TRT02EDTM":"2023-06-03 17:28:44","AP01SDTM":"2020-06-02 23:28:44","AP01EDTM":"2022-06-03 11:28:44","AP02SDTM":"2022-06-03 11:28:44","AP02EDTM":"2023-06-03 17:28:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-03","EOSDY":1096,"LSTALVDT":"2023-06-22","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5458,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.91811,"AVALU":"mg/L","BASE2":7.63589,"BASE":10.13732,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.71778,"PCHG2":-9.40006,"CHG":-3.21921,"PCHG":-31.75603,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-1","BTOXGR":"3","ADTM":"2021-11-03 23:28:44","ADY":519,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-275","SUBJID":"id-275","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.14151,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-01","TRTSDTM":"2020-06-02 23:28:44","TRTEDTM":"2023-06-03 17:28:44","TRT01SDTM":"2020-06-02 23:28:44","TRT01EDTM":"2022-06-03 11:28:44","TRT02SDTM":"2022-06-03 11:28:44","TRT02EDTM":"2023-06-03 17:28:44","AP01SDTM":"2020-06-02 23:28:44","AP01EDTM":"2022-06-03 11:28:44","AP02SDTM":"2022-06-03 11:28:44","AP02EDTM":"2023-06-03 17:28:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-03","EOSDY":1096,"LSTALVDT":"2023-06-22","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6254,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.869,"AVALU":"mg/L","BASE2":7.63589,"BASE":10.13732,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.23311,"PCHG2":42.34099,"CHG":0.73168,"PCHG":7.21767,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"4","BTOXGR":"3","ADTM":"2022-01-16 23:28:44","ADY":593,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-275","SUBJID":"id-275","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.14151,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-01","TRTSDTM":"2020-06-02 23:28:44","TRTEDTM":"2023-06-03 17:28:44","TRT01SDTM":"2020-06-02 23:28:44","TRT01EDTM":"2022-06-03 11:28:44","TRT02SDTM":"2022-06-03 11:28:44","TRT02EDTM":"2023-06-03 17:28:44","AP01SDTM":"2020-06-02 23:28:44","AP01EDTM":"2022-06-03 11:28:44","AP02SDTM":"2022-06-03 11:28:44","AP02EDTM":"2023-06-03 17:28:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-03","EOSDY":1096,"LSTALVDT":"2023-06-22","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2080,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.28479,"AVALU":"mg/L","BASE2":7.63589,"BASE":10.13732,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.6489,"PCHG2":8.49803,"CHG":-1.85253,"PCHG":-18.27437,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-09-24 23:28:44","ADY":844,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-275","SUBJID":"id-275","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.14151,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-01","TRTSDTM":"2020-06-02 23:28:44","TRTEDTM":"2023-06-03 17:28:44","TRT01SDTM":"2020-06-02 23:28:44","TRT01EDTM":"2022-06-03 11:28:44","TRT02SDTM":"2022-06-03 11:28:44","TRT02EDTM":"2023-06-03 17:28:44","AP01SDTM":"2020-06-02 23:28:44","AP01EDTM":"2022-06-03 11:28:44","AP02SDTM":"2022-06-03 11:28:44","AP02EDTM":"2023-06-03 17:28:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-03","EOSDY":1096,"LSTALVDT":"2023-06-22","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7340,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.21941,"AVALU":"mg/L","BASE2":7.63589,"BASE":10.13732,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.58352,"PCHG2":20.73787,"CHG":-0.91791,"PCHG":-9.05477,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2023-04-01 23:28:44","ADY":1033,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-275","SUBJID":"id-275","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.14151,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-01","TRTSDTM":"2020-06-02 23:28:44","TRTEDTM":"2023-06-03 17:28:44","TRT01SDTM":"2020-06-02 23:28:44","TRT01EDTM":"2022-06-03 11:28:44","TRT02SDTM":"2022-06-03 11:28:44","TRT02EDTM":"2023-06-03 17:28:44","AP01SDTM":"2020-06-02 23:28:44","AP01EDTM":"2022-06-03 11:28:44","AP02SDTM":"2022-06-03 11:28:44","AP02EDTM":"2023-06-03 17:28:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-03","EOSDY":1096,"LSTALVDT":"2023-06-22","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3066,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04087,"AVALU":"g/L","BASE2":3.04087,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-06-14 23:28:44","ADY":12,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-275","SUBJID":"id-275","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.14151,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-01","TRTSDTM":"2020-06-02 23:28:44","TRTEDTM":"2023-06-03 17:28:44","TRT01SDTM":"2020-06-02 23:28:44","TRT01EDTM":"2022-06-03 11:28:44","TRT02SDTM":"2022-06-03 11:28:44","TRT02EDTM":"2023-06-03 17:28:44","AP01SDTM":"2020-06-02 23:28:44","AP01EDTM":"2022-06-03 11:28:44","AP02SDTM":"2022-06-03 11:28:44","AP02EDTM":"2023-06-03 17:28:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-03","EOSDY":1096,"LSTALVDT":"2023-06-22","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7769,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89552,"AVALU":"g/L","BASE2":3.04087,"BASE":2.89552,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.14535,"PCHG2":-4.77973,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-17 23:28:44","ADY":260,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-275","SUBJID":"id-275","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.14151,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-01","TRTSDTM":"2020-06-02 23:28:44","TRTEDTM":"2023-06-03 17:28:44","TRT01SDTM":"2020-06-02 23:28:44","TRT01EDTM":"2022-06-03 11:28:44","TRT02SDTM":"2022-06-03 11:28:44","TRT02EDTM":"2023-06-03 17:28:44","AP01SDTM":"2020-06-02 23:28:44","AP01EDTM":"2022-06-03 11:28:44","AP02SDTM":"2022-06-03 11:28:44","AP02EDTM":"2023-06-03 17:28:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-03","EOSDY":1096,"LSTALVDT":"2023-06-22","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":372,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03516,"AVALU":"g/L","BASE2":3.04087,"BASE":2.89552,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0057,"PCHG2":-0.18751,"CHG":0.13964,"PCHG":4.82273,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2021-06-01 23:28:44","ADY":364,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-275","SUBJID":"id-275","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.14151,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-01","TRTSDTM":"2020-06-02 23:28:44","TRTEDTM":"2023-06-03 17:28:44","TRT01SDTM":"2020-06-02 23:28:44","TRT01EDTM":"2022-06-03 11:28:44","TRT02SDTM":"2022-06-03 11:28:44","TRT02EDTM":"2023-06-03 17:28:44","AP01SDTM":"2020-06-02 23:28:44","AP01EDTM":"2022-06-03 11:28:44","AP02SDTM":"2022-06-03 11:28:44","AP02EDTM":"2023-06-03 17:28:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-03","EOSDY":1096,"LSTALVDT":"2023-06-22","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":743,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7682,"AVALU":"g/L","BASE2":3.04087,"BASE":2.89552,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.27266,"PCHG2":-8.96668,"CHG":-0.12732,"PCHG":-4.39712,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-03 23:28:44","ADY":519,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-275","SUBJID":"id-275","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.14151,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-01","TRTSDTM":"2020-06-02 23:28:44","TRTEDTM":"2023-06-03 17:28:44","TRT01SDTM":"2020-06-02 23:28:44","TRT01EDTM":"2022-06-03 11:28:44","TRT02SDTM":"2022-06-03 11:28:44","TRT02EDTM":"2023-06-03 17:28:44","AP01SDTM":"2020-06-02 23:28:44","AP01EDTM":"2022-06-03 11:28:44","AP02SDTM":"2022-06-03 11:28:44","AP02EDTM":"2023-06-03 17:28:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-03","EOSDY":1096,"LSTALVDT":"2023-06-22","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6844,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93307,"AVALU":"g/L","BASE2":3.04087,"BASE":2.89552,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10779,"PCHG2":-3.54481,"CHG":0.03755,"PCHG":1.2969,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-16 23:28:44","ADY":593,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-275","SUBJID":"id-275","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.14151,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-01","TRTSDTM":"2020-06-02 23:28:44","TRTEDTM":"2023-06-03 17:28:44","TRT01SDTM":"2020-06-02 23:28:44","TRT01EDTM":"2022-06-03 11:28:44","TRT02SDTM":"2022-06-03 11:28:44","TRT02EDTM":"2023-06-03 17:28:44","AP01SDTM":"2020-06-02 23:28:44","AP01EDTM":"2022-06-03 11:28:44","AP02SDTM":"2022-06-03 11:28:44","AP02EDTM":"2023-06-03 17:28:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-03","EOSDY":1096,"LSTALVDT":"2023-06-22","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5806,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88645,"AVALU":"g/L","BASE2":3.04087,"BASE":2.89552,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15441,"PCHG2":-5.07787,"CHG":-0.00907,"PCHG":-0.31311,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-24 23:28:44","ADY":844,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-275","SUBJID":"id-275","SITEID":"CHN-1","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.14151,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-01","TRTSDTM":"2020-06-02 23:28:44","TRTEDTM":"2023-06-03 17:28:44","TRT01SDTM":"2020-06-02 23:28:44","TRT01EDTM":"2022-06-03 11:28:44","TRT02SDTM":"2022-06-03 11:28:44","TRT02EDTM":"2023-06-03 17:28:44","AP01SDTM":"2020-06-02 23:28:44","AP01EDTM":"2022-06-03 11:28:44","AP02SDTM":"2022-06-03 11:28:44","AP02EDTM":"2023-06-03 17:28:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-03","EOSDY":1096,"LSTALVDT":"2023-06-22","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":631,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96926,"AVALU":"g/L","BASE2":3.04087,"BASE":2.89552,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0716,"PCHG2":-2.35467,"CHG":0.07374,"PCHG":2.54679,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-01 23:28:44","ADY":1033,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-276","SUBJID":"id-276","SITEID":"CHN-1","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.68599,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 05:17:41","TRTEDTM":"2023-10-24 23:17:41","TRT01SDTM":"2020-10-24 05:17:41","TRT01EDTM":"2022-10-24 17:17:41","TRT02SDTM":"2022-10-24 17:17:41","TRT02EDTM":"2023-10-24 23:17:41","AP01SDTM":"2020-10-24 05:17:41","AP01EDTM":"2022-10-24 17:17:41","AP02SDTM":"2022-10-24 17:17:41","AP02EDTM":"2023-10-24 23:17:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-24","EOSDY":1096,"LSTALVDT":"2023-11-08","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6059,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.64435,"AVALU":"U/L","BASE2":31.64435,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-24 05:17:41","ADY":304,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-276","SUBJID":"id-276","SITEID":"CHN-1","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.68599,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 05:17:41","TRTEDTM":"2023-10-24 23:17:41","TRT01SDTM":"2020-10-24 05:17:41","TRT01EDTM":"2022-10-24 17:17:41","TRT02SDTM":"2022-10-24 17:17:41","TRT02EDTM":"2023-10-24 23:17:41","AP01SDTM":"2020-10-24 05:17:41","AP01EDTM":"2022-10-24 17:17:41","AP02SDTM":"2022-10-24 17:17:41","AP02EDTM":"2023-10-24 23:17:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-24","EOSDY":1096,"LSTALVDT":"2023-11-08","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3072,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.28489,"AVALU":"U/L","BASE2":31.64435,"BASE":29.28489,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.35946,"PCHG2":-7.45618,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-28 05:17:41","ADY":551,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-276","SUBJID":"id-276","SITEID":"CHN-1","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.68599,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 05:17:41","TRTEDTM":"2023-10-24 23:17:41","TRT01SDTM":"2020-10-24 05:17:41","TRT01EDTM":"2022-10-24 17:17:41","TRT02SDTM":"2022-10-24 17:17:41","TRT02EDTM":"2023-10-24 23:17:41","AP01SDTM":"2020-10-24 05:17:41","AP01EDTM":"2022-10-24 17:17:41","AP02SDTM":"2022-10-24 17:17:41","AP02EDTM":"2023-10-24 23:17:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-24","EOSDY":1096,"LSTALVDT":"2023-11-08","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3580,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.53747,"AVALU":"U/L","BASE2":31.64435,"BASE":29.28489,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.10688,"PCHG2":-50.89969,"CHG":-13.74742,"PCHG":-46.94372,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-21 05:17:41","ADY":574,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-276","SUBJID":"id-276","SITEID":"CHN-1","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.68599,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 05:17:41","TRTEDTM":"2023-10-24 23:17:41","TRT01SDTM":"2020-10-24 05:17:41","TRT01EDTM":"2022-10-24 17:17:41","TRT02SDTM":"2022-10-24 17:17:41","TRT02EDTM":"2023-10-24 23:17:41","AP01SDTM":"2020-10-24 05:17:41","AP01EDTM":"2022-10-24 17:17:41","AP02SDTM":"2022-10-24 17:17:41","AP02EDTM":"2023-10-24 23:17:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-24","EOSDY":1096,"LSTALVDT":"2023-11-08","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2270,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.41791,"AVALU":"U/L","BASE2":31.64435,"BASE":29.28489,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.22644,"PCHG2":-22.83642,"CHG":-4.86698,"PCHG":-16.61942,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-05 05:17:41","ADY":589,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-276","SUBJID":"id-276","SITEID":"CHN-1","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.68599,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 05:17:41","TRTEDTM":"2023-10-24 23:17:41","TRT01SDTM":"2020-10-24 05:17:41","TRT01EDTM":"2022-10-24 17:17:41","TRT02SDTM":"2022-10-24 17:17:41","TRT02EDTM":"2023-10-24 23:17:41","AP01SDTM":"2020-10-24 05:17:41","AP01EDTM":"2022-10-24 17:17:41","AP02SDTM":"2022-10-24 17:17:41","AP02EDTM":"2023-10-24 23:17:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-24","EOSDY":1096,"LSTALVDT":"2023-11-08","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2699,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.13258,"AVALU":"U/L","BASE2":31.64435,"BASE":29.28489,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.51177,"PCHG2":-4.77739,"CHG":0.84769,"PCHG":2.89462,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-12 05:17:41","ADY":657,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-276","SUBJID":"id-276","SITEID":"CHN-1","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.68599,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 05:17:41","TRTEDTM":"2023-10-24 23:17:41","TRT01SDTM":"2020-10-24 05:17:41","TRT01EDTM":"2022-10-24 17:17:41","TRT02SDTM":"2022-10-24 17:17:41","TRT02EDTM":"2023-10-24 23:17:41","AP01SDTM":"2020-10-24 05:17:41","AP01EDTM":"2022-10-24 17:17:41","AP02SDTM":"2022-10-24 17:17:41","AP02EDTM":"2023-10-24 23:17:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-24","EOSDY":1096,"LSTALVDT":"2023-11-08","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7243,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.17808,"AVALU":"U/L","BASE2":31.64435,"BASE":29.28489,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.46627,"PCHG2":-52.03541,"CHG":-14.10681,"PCHG":-48.17095,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-01 05:17:41","ADY":738,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-276","SUBJID":"id-276","SITEID":"CHN-1","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.68599,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 05:17:41","TRTEDTM":"2023-10-24 23:17:41","TRT01SDTM":"2020-10-24 05:17:41","TRT01EDTM":"2022-10-24 17:17:41","TRT02SDTM":"2022-10-24 17:17:41","TRT02EDTM":"2023-10-24 23:17:41","AP01SDTM":"2020-10-24 05:17:41","AP01EDTM":"2022-10-24 17:17:41","AP02SDTM":"2022-10-24 17:17:41","AP02EDTM":"2023-10-24 23:17:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-24","EOSDY":1096,"LSTALVDT":"2023-11-08","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6938,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.32399,"AVALU":"U/L","BASE2":31.64435,"BASE":29.28489,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-18.32036,"PCHG2":-57.89457,"CHG":-15.9609,"PCHG":-54.50217,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-29 05:17:41","ADY":978,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-276","SUBJID":"id-276","SITEID":"CHN-1","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.68599,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 05:17:41","TRTEDTM":"2023-10-24 23:17:41","TRT01SDTM":"2020-10-24 05:17:41","TRT01EDTM":"2022-10-24 17:17:41","TRT02SDTM":"2022-10-24 17:17:41","TRT02EDTM":"2023-10-24 23:17:41","AP01SDTM":"2020-10-24 05:17:41","AP01EDTM":"2022-10-24 17:17:41","AP02SDTM":"2022-10-24 17:17:41","AP02EDTM":"2023-10-24 23:17:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-24","EOSDY":1096,"LSTALVDT":"2023-11-08","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3133,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.67561,"AVALU":"mg/L","BASE2":9.67561,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"4","ADTM":"2021-08-24 05:17:41","ADY":304,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-276","SUBJID":"id-276","SITEID":"CHN-1","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.68599,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 05:17:41","TRTEDTM":"2023-10-24 23:17:41","TRT01SDTM":"2020-10-24 05:17:41","TRT01EDTM":"2022-10-24 17:17:41","TRT02SDTM":"2022-10-24 17:17:41","TRT02EDTM":"2023-10-24 23:17:41","AP01SDTM":"2020-10-24 05:17:41","AP01EDTM":"2022-10-24 17:17:41","AP02SDTM":"2022-10-24 17:17:41","AP02EDTM":"2023-10-24 23:17:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-24","EOSDY":1096,"LSTALVDT":"2023-11-08","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5609,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.13442,"AVALU":"mg/L","BASE2":9.67561,"BASE":10.13442,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.45881,"PCHG2":4.74194,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"4","BTOXGR":"4","ADTM":"2022-04-28 05:17:41","ADY":551,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-276","SUBJID":"id-276","SITEID":"CHN-1","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.68599,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 05:17:41","TRTEDTM":"2023-10-24 23:17:41","TRT01SDTM":"2020-10-24 05:17:41","TRT01EDTM":"2022-10-24 17:17:41","TRT02SDTM":"2022-10-24 17:17:41","TRT02EDTM":"2023-10-24 23:17:41","AP01SDTM":"2020-10-24 05:17:41","AP01EDTM":"2022-10-24 17:17:41","AP02SDTM":"2022-10-24 17:17:41","AP02EDTM":"2023-10-24 23:17:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-24","EOSDY":1096,"LSTALVDT":"2023-11-08","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4792,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.68942,"AVALU":"mg/L","BASE2":9.67561,"BASE":10.13442,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01381,"PCHG2":0.14272,"CHG":-0.445,"PCHG":-4.391,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2022-05-21 05:17:41","ADY":574,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-276","SUBJID":"id-276","SITEID":"CHN-1","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.68599,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 05:17:41","TRTEDTM":"2023-10-24 23:17:41","TRT01SDTM":"2020-10-24 05:17:41","TRT01EDTM":"2022-10-24 17:17:41","TRT02SDTM":"2022-10-24 17:17:41","TRT02EDTM":"2023-10-24 23:17:41","AP01SDTM":"2020-10-24 05:17:41","AP01EDTM":"2022-10-24 17:17:41","AP02SDTM":"2022-10-24 17:17:41","AP02EDTM":"2023-10-24 23:17:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-24","EOSDY":1096,"LSTALVDT":"2023-11-08","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5953,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.56258,"AVALU":"mg/L","BASE2":9.67561,"BASE":10.13442,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11303,"PCHG2":-1.16817,"CHG":-0.57184,"PCHG":-5.64255,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2022-06-05 05:17:41","ADY":589,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-276","SUBJID":"id-276","SITEID":"CHN-1","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.68599,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 05:17:41","TRTEDTM":"2023-10-24 23:17:41","TRT01SDTM":"2020-10-24 05:17:41","TRT01EDTM":"2022-10-24 17:17:41","TRT02SDTM":"2022-10-24 17:17:41","TRT02EDTM":"2023-10-24 23:17:41","AP01SDTM":"2020-10-24 05:17:41","AP01EDTM":"2022-10-24 17:17:41","AP02SDTM":"2022-10-24 17:17:41","AP02EDTM":"2023-10-24 23:17:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-24","EOSDY":1096,"LSTALVDT":"2023-11-08","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4683,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.13565,"AVALU":"mg/L","BASE2":9.67561,"BASE":10.13442,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.53996,"PCHG2":-15.9159,"CHG":-1.99877,"PCHG":-19.7226,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2022-08-12 05:17:41","ADY":657,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-276","SUBJID":"id-276","SITEID":"CHN-1","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.68599,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 05:17:41","TRTEDTM":"2023-10-24 23:17:41","TRT01SDTM":"2020-10-24 05:17:41","TRT01EDTM":"2022-10-24 17:17:41","TRT02SDTM":"2022-10-24 17:17:41","TRT02EDTM":"2023-10-24 23:17:41","AP01SDTM":"2020-10-24 05:17:41","AP01EDTM":"2022-10-24 17:17:41","AP02SDTM":"2022-10-24 17:17:41","AP02EDTM":"2023-10-24 23:17:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-24","EOSDY":1096,"LSTALVDT":"2023-11-08","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7084,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.20665,"AVALU":"mg/L","BASE2":9.67561,"BASE":10.13442,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.53104,"PCHG2":15.8237,"CHG":1.07223,"PCHG":10.58006,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"1","BTOXGR":"4","ADTM":"2022-11-01 05:17:41","ADY":738,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-276","SUBJID":"id-276","SITEID":"CHN-1","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.68599,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 05:17:41","TRTEDTM":"2023-10-24 23:17:41","TRT01SDTM":"2020-10-24 05:17:41","TRT01EDTM":"2022-10-24 17:17:41","TRT02SDTM":"2022-10-24 17:17:41","TRT02EDTM":"2023-10-24 23:17:41","AP01SDTM":"2020-10-24 05:17:41","AP01EDTM":"2022-10-24 17:17:41","AP02SDTM":"2022-10-24 17:17:41","AP02EDTM":"2023-10-24 23:17:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-24","EOSDY":1096,"LSTALVDT":"2023-11-08","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5521,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.03329,"AVALU":"mg/L","BASE2":9.67561,"BASE":10.13442,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.64232,"PCHG2":-16.97382,"CHG":-2.10113,"PCHG":-20.73263,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2023-06-29 05:17:41","ADY":978,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-276","SUBJID":"id-276","SITEID":"CHN-1","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.68599,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 05:17:41","TRTEDTM":"2023-10-24 23:17:41","TRT01SDTM":"2020-10-24 05:17:41","TRT01EDTM":"2022-10-24 17:17:41","TRT02SDTM":"2022-10-24 17:17:41","TRT02EDTM":"2023-10-24 23:17:41","AP01SDTM":"2020-10-24 05:17:41","AP01EDTM":"2022-10-24 17:17:41","AP02SDTM":"2022-10-24 17:17:41","AP02EDTM":"2023-10-24 23:17:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-24","EOSDY":1096,"LSTALVDT":"2023-11-08","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7123,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82221,"AVALU":"g/L","BASE2":2.82221,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-24 05:17:41","ADY":304,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-276","SUBJID":"id-276","SITEID":"CHN-1","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.68599,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 05:17:41","TRTEDTM":"2023-10-24 23:17:41","TRT01SDTM":"2020-10-24 05:17:41","TRT01EDTM":"2022-10-24 17:17:41","TRT02SDTM":"2022-10-24 17:17:41","TRT02EDTM":"2023-10-24 23:17:41","AP01SDTM":"2020-10-24 05:17:41","AP01EDTM":"2022-10-24 17:17:41","AP02SDTM":"2022-10-24 17:17:41","AP02EDTM":"2023-10-24 23:17:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-24","EOSDY":1096,"LSTALVDT":"2023-11-08","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7241,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84109,"AVALU":"g/L","BASE2":2.82221,"BASE":2.84109,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.01888,"PCHG2":0.66906,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-28 05:17:41","ADY":551,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-276","SUBJID":"id-276","SITEID":"CHN-1","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.68599,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 05:17:41","TRTEDTM":"2023-10-24 23:17:41","TRT01SDTM":"2020-10-24 05:17:41","TRT01EDTM":"2022-10-24 17:17:41","TRT02SDTM":"2022-10-24 17:17:41","TRT02EDTM":"2023-10-24 23:17:41","AP01SDTM":"2020-10-24 05:17:41","AP01EDTM":"2022-10-24 17:17:41","AP02SDTM":"2022-10-24 17:17:41","AP02EDTM":"2023-10-24 23:17:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-24","EOSDY":1096,"LSTALVDT":"2023-11-08","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7438,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90258,"AVALU":"g/L","BASE2":2.82221,"BASE":2.84109,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08037,"PCHG2":2.84791,"CHG":0.06149,"PCHG":2.16438,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-21 05:17:41","ADY":574,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-276","SUBJID":"id-276","SITEID":"CHN-1","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.68599,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 05:17:41","TRTEDTM":"2023-10-24 23:17:41","TRT01SDTM":"2020-10-24 05:17:41","TRT01EDTM":"2022-10-24 17:17:41","TRT02SDTM":"2022-10-24 17:17:41","TRT02EDTM":"2023-10-24 23:17:41","AP01SDTM":"2020-10-24 05:17:41","AP01EDTM":"2022-10-24 17:17:41","AP02SDTM":"2022-10-24 17:17:41","AP02EDTM":"2023-10-24 23:17:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-24","EOSDY":1096,"LSTALVDT":"2023-11-08","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":962,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97762,"AVALU":"g/L","BASE2":2.82221,"BASE":2.84109,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15541,"PCHG2":5.50669,"CHG":0.13653,"PCHG":4.80549,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-05 05:17:41","ADY":589,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-276","SUBJID":"id-276","SITEID":"CHN-1","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.68599,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 05:17:41","TRTEDTM":"2023-10-24 23:17:41","TRT01SDTM":"2020-10-24 05:17:41","TRT01EDTM":"2022-10-24 17:17:41","TRT02SDTM":"2022-10-24 17:17:41","TRT02EDTM":"2023-10-24 23:17:41","AP01SDTM":"2020-10-24 05:17:41","AP01EDTM":"2022-10-24 17:17:41","AP02SDTM":"2022-10-24 17:17:41","AP02EDTM":"2023-10-24 23:17:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-24","EOSDY":1096,"LSTALVDT":"2023-11-08","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1747,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89926,"AVALU":"g/L","BASE2":2.82221,"BASE":2.84109,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07706,"PCHG2":2.73033,"CHG":0.05817,"PCHG":2.04757,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-12 05:17:41","ADY":657,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-276","SUBJID":"id-276","SITEID":"CHN-1","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.68599,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 05:17:41","TRTEDTM":"2023-10-24 23:17:41","TRT01SDTM":"2020-10-24 05:17:41","TRT01EDTM":"2022-10-24 17:17:41","TRT02SDTM":"2022-10-24 17:17:41","TRT02EDTM":"2023-10-24 23:17:41","AP01SDTM":"2020-10-24 05:17:41","AP01EDTM":"2022-10-24 17:17:41","AP02SDTM":"2022-10-24 17:17:41","AP02EDTM":"2023-10-24 23:17:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-24","EOSDY":1096,"LSTALVDT":"2023-11-08","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1780,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86736,"AVALU":"g/L","BASE2":2.82221,"BASE":2.84109,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04515,"PCHG2":1.59994,"CHG":0.02627,"PCHG":0.9247,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-01 05:17:41","ADY":738,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-276","SUBJID":"id-276","SITEID":"CHN-1","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.68599,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 05:17:41","TRTEDTM":"2023-10-24 23:17:41","TRT01SDTM":"2020-10-24 05:17:41","TRT01EDTM":"2022-10-24 17:17:41","TRT02SDTM":"2022-10-24 17:17:41","TRT02EDTM":"2023-10-24 23:17:41","AP01SDTM":"2020-10-24 05:17:41","AP01EDTM":"2022-10-24 17:17:41","AP02SDTM":"2022-10-24 17:17:41","AP02EDTM":"2023-10-24 23:17:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-24","EOSDY":1096,"LSTALVDT":"2023-11-08","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1619,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90393,"AVALU":"g/L","BASE2":2.82221,"BASE":2.84109,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08172,"PCHG2":2.89548,"CHG":0.06283,"PCHG":2.21162,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-29 05:17:41","ADY":978,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-277","SUBJID":"id-277","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.07227,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 17:03:48","TRTEDTM":"2024-01-15 11:03:48","TRT01SDTM":"2021-01-14 17:03:48","TRT01EDTM":"2023-01-15 05:03:48","TRT02SDTM":"2023-01-15 05:03:48","TRT02EDTM":"2024-01-15 11:03:48","AP01SDTM":"2021-01-14 17:03:48","AP01EDTM":"2023-01-15 05:03:48","AP02SDTM":"2023-01-15 05:03:48","AP02EDTM":"2024-01-15 11:03:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1714,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.76793,"AVALU":"U/L","BASE2":8.76793,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-11-04 17:03:48","ADY":294,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-277","SUBJID":"id-277","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.07227,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 17:03:48","TRTEDTM":"2024-01-15 11:03:48","TRT01SDTM":"2021-01-14 17:03:48","TRT01EDTM":"2023-01-15 05:03:48","TRT02SDTM":"2023-01-15 05:03:48","TRT02EDTM":"2024-01-15 11:03:48","AP01SDTM":"2021-01-14 17:03:48","AP01EDTM":"2023-01-15 05:03:48","AP02SDTM":"2023-01-15 05:03:48","AP02EDTM":"2024-01-15 11:03:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7280,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.08736,"AVALU":"U/L","BASE2":8.76793,"BASE":1.08736,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-7.68057,"PCHG2":-87.5984,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-4","BTOXGR":"-4","ADTM":"2022-05-12 17:03:48","ADY":483,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-277","SUBJID":"id-277","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.07227,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 17:03:48","TRTEDTM":"2024-01-15 11:03:48","TRT01SDTM":"2021-01-14 17:03:48","TRT01EDTM":"2023-01-15 05:03:48","TRT02SDTM":"2023-01-15 05:03:48","TRT02EDTM":"2024-01-15 11:03:48","AP01SDTM":"2021-01-14 17:03:48","AP01EDTM":"2023-01-15 05:03:48","AP02SDTM":"2023-01-15 05:03:48","AP02EDTM":"2024-01-15 11:03:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1127,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.52904,"AVALU":"U/L","BASE2":8.76793,"BASE":1.08736,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.76111,"PCHG2":225.37941,"CHG":27.44168,"PCHG":2523.68945,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2022-08-07 17:03:48","ADY":570,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-277","SUBJID":"id-277","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.07227,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 17:03:48","TRTEDTM":"2024-01-15 11:03:48","TRT01SDTM":"2021-01-14 17:03:48","TRT01EDTM":"2023-01-15 05:03:48","TRT02SDTM":"2023-01-15 05:03:48","TRT02EDTM":"2024-01-15 11:03:48","AP01SDTM":"2021-01-14 17:03:48","AP01EDTM":"2023-01-15 05:03:48","AP02SDTM":"2023-01-15 05:03:48","AP02EDTM":"2024-01-15 11:03:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3408,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.81788,"AVALU":"U/L","BASE2":8.76793,"BASE":1.08736,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.04995,"PCHG2":137.43206,"CHG":19.73051,"PCHG":1814.52803,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2022-10-08 17:03:48","ADY":632,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-277","SUBJID":"id-277","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.07227,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 17:03:48","TRTEDTM":"2024-01-15 11:03:48","TRT01SDTM":"2021-01-14 17:03:48","TRT01EDTM":"2023-01-15 05:03:48","TRT02SDTM":"2023-01-15 05:03:48","TRT02EDTM":"2024-01-15 11:03:48","AP01SDTM":"2021-01-14 17:03:48","AP01EDTM":"2023-01-15 05:03:48","AP02SDTM":"2023-01-15 05:03:48","AP02EDTM":"2024-01-15 11:03:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6200,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.40284,"AVALU":"U/L","BASE2":8.76793,"BASE":1.08736,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.63491,"PCHG2":144.10367,"CHG":20.31548,"PCHG":1868.32441,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2023-02-02 17:03:48","ADY":749,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-277","SUBJID":"id-277","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.07227,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 17:03:48","TRTEDTM":"2024-01-15 11:03:48","TRT01SDTM":"2021-01-14 17:03:48","TRT01EDTM":"2023-01-15 05:03:48","TRT02SDTM":"2023-01-15 05:03:48","TRT02EDTM":"2024-01-15 11:03:48","AP01SDTM":"2021-01-14 17:03:48","AP01EDTM":"2023-01-15 05:03:48","AP02SDTM":"2023-01-15 05:03:48","AP02EDTM":"2024-01-15 11:03:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8170,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.1847,"AVALU":"U/L","BASE2":8.76793,"BASE":1.08736,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.41677,"PCHG2":130.21057,"CHG":19.09734,"PCHG":1756.29767,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2023-04-24 17:03:48","ADY":830,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-277","SUBJID":"id-277","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.07227,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 17:03:48","TRTEDTM":"2024-01-15 11:03:48","TRT01SDTM":"2021-01-14 17:03:48","TRT01EDTM":"2023-01-15 05:03:48","TRT02SDTM":"2023-01-15 05:03:48","TRT02EDTM":"2024-01-15 11:03:48","AP01SDTM":"2021-01-14 17:03:48","AP01EDTM":"2023-01-15 05:03:48","AP02SDTM":"2023-01-15 05:03:48","AP02EDTM":"2024-01-15 11:03:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6565,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.21512,"AVALU":"U/L","BASE2":8.76793,"BASE":1.08736,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.44719,"PCHG2":16.50547,"CHG":9.12776,"PCHG":839.43922,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2023-08-06 17:03:48","ADY":934,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-277","SUBJID":"id-277","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.07227,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 17:03:48","TRTEDTM":"2024-01-15 11:03:48","TRT01SDTM":"2021-01-14 17:03:48","TRT01EDTM":"2023-01-15 05:03:48","TRT02SDTM":"2023-01-15 05:03:48","TRT02EDTM":"2024-01-15 11:03:48","AP01SDTM":"2021-01-14 17:03:48","AP01EDTM":"2023-01-15 05:03:48","AP02SDTM":"2023-01-15 05:03:48","AP02EDTM":"2024-01-15 11:03:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":455,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.70148,"AVALU":"mg/L","BASE2":9.70148,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-04 17:03:48","ADY":294,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-277","SUBJID":"id-277","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.07227,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 17:03:48","TRTEDTM":"2024-01-15 11:03:48","TRT01SDTM":"2021-01-14 17:03:48","TRT01EDTM":"2023-01-15 05:03:48","TRT02SDTM":"2023-01-15 05:03:48","TRT02EDTM":"2024-01-15 11:03:48","AP01SDTM":"2021-01-14 17:03:48","AP01EDTM":"2023-01-15 05:03:48","AP02SDTM":"2023-01-15 05:03:48","AP02EDTM":"2024-01-15 11:03:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":229,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.61658,"AVALU":"mg/L","BASE2":9.70148,"BASE":8.61658,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.08491,"PCHG2":-11.1829,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-12 17:03:48","ADY":483,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-277","SUBJID":"id-277","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.07227,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 17:03:48","TRTEDTM":"2024-01-15 11:03:48","TRT01SDTM":"2021-01-14 17:03:48","TRT01EDTM":"2023-01-15 05:03:48","TRT02SDTM":"2023-01-15 05:03:48","TRT02EDTM":"2024-01-15 11:03:48","AP01SDTM":"2021-01-14 17:03:48","AP01EDTM":"2023-01-15 05:03:48","AP02SDTM":"2023-01-15 05:03:48","AP02EDTM":"2024-01-15 11:03:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5825,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.44293,"AVALU":"mg/L","BASE2":9.70148,"BASE":8.61658,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.74145,"PCHG2":7.6426,"CHG":1.82635,"PCHG":21.19581,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-08-07 17:03:48","ADY":570,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-277","SUBJID":"id-277","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.07227,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 17:03:48","TRTEDTM":"2024-01-15 11:03:48","TRT01SDTM":"2021-01-14 17:03:48","TRT01EDTM":"2023-01-15 05:03:48","TRT02SDTM":"2023-01-15 05:03:48","TRT02EDTM":"2024-01-15 11:03:48","AP01SDTM":"2021-01-14 17:03:48","AP01EDTM":"2023-01-15 05:03:48","AP02SDTM":"2023-01-15 05:03:48","AP02EDTM":"2024-01-15 11:03:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4909,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.32977,"AVALU":"mg/L","BASE2":9.70148,"BASE":8.61658,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.37171,"PCHG2":-14.13918,"CHG":-0.2868,"PCHG":-3.3285,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-08 17:03:48","ADY":632,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-277","SUBJID":"id-277","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.07227,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 17:03:48","TRTEDTM":"2024-01-15 11:03:48","TRT01SDTM":"2021-01-14 17:03:48","TRT01EDTM":"2023-01-15 05:03:48","TRT02SDTM":"2023-01-15 05:03:48","TRT02EDTM":"2024-01-15 11:03:48","AP01SDTM":"2021-01-14 17:03:48","AP01EDTM":"2023-01-15 05:03:48","AP02SDTM":"2023-01-15 05:03:48","AP02EDTM":"2024-01-15 11:03:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6709,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.10253,"AVALU":"mg/L","BASE2":9.70148,"BASE":8.61658,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.40104,"PCHG2":4.13383,"CHG":1.48595,"PCHG":17.24525,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2023-02-02 17:03:48","ADY":749,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-277","SUBJID":"id-277","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.07227,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 17:03:48","TRTEDTM":"2024-01-15 11:03:48","TRT01SDTM":"2021-01-14 17:03:48","TRT01EDTM":"2023-01-15 05:03:48","TRT02SDTM":"2023-01-15 05:03:48","TRT02EDTM":"2024-01-15 11:03:48","AP01SDTM":"2021-01-14 17:03:48","AP01EDTM":"2023-01-15 05:03:48","AP02SDTM":"2023-01-15 05:03:48","AP02EDTM":"2024-01-15 11:03:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5283,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.09006,"AVALU":"mg/L","BASE2":9.70148,"BASE":8.61658,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.61143,"PCHG2":-16.6101,"CHG":-0.52652,"PCHG":-6.11054,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-24 17:03:48","ADY":830,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-277","SUBJID":"id-277","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.07227,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 17:03:48","TRTEDTM":"2024-01-15 11:03:48","TRT01SDTM":"2021-01-14 17:03:48","TRT01EDTM":"2023-01-15 05:03:48","TRT02SDTM":"2023-01-15 05:03:48","TRT02EDTM":"2024-01-15 11:03:48","AP01SDTM":"2021-01-14 17:03:48","AP01EDTM":"2023-01-15 05:03:48","AP02SDTM":"2023-01-15 05:03:48","AP02EDTM":"2024-01-15 11:03:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1907,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.85095,"AVALU":"mg/L","BASE2":9.70148,"BASE":8.61658,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.85053,"PCHG2":-19.07474,"CHG":-0.76563,"PCHG":-8.8855,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2023-08-06 17:03:48","ADY":934,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-277","SUBJID":"id-277","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.07227,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 17:03:48","TRTEDTM":"2024-01-15 11:03:48","TRT01SDTM":"2021-01-14 17:03:48","TRT01EDTM":"2023-01-15 05:03:48","TRT02SDTM":"2023-01-15 05:03:48","TRT02EDTM":"2024-01-15 11:03:48","AP01SDTM":"2021-01-14 17:03:48","AP01EDTM":"2023-01-15 05:03:48","AP02SDTM":"2023-01-15 05:03:48","AP02EDTM":"2024-01-15 11:03:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3254,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0439,"AVALU":"g/L","BASE2":3.0439,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-11-04 17:03:48","ADY":294,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-277","SUBJID":"id-277","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.07227,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 17:03:48","TRTEDTM":"2024-01-15 11:03:48","TRT01SDTM":"2021-01-14 17:03:48","TRT01EDTM":"2023-01-15 05:03:48","TRT02SDTM":"2023-01-15 05:03:48","TRT02EDTM":"2024-01-15 11:03:48","AP01SDTM":"2021-01-14 17:03:48","AP01EDTM":"2023-01-15 05:03:48","AP02SDTM":"2023-01-15 05:03:48","AP02EDTM":"2024-01-15 11:03:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2251,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90751,"AVALU":"g/L","BASE2":3.0439,"BASE":2.90751,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.13638,"PCHG2":-4.48059,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-12 17:03:48","ADY":483,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-277","SUBJID":"id-277","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.07227,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 17:03:48","TRTEDTM":"2024-01-15 11:03:48","TRT01SDTM":"2021-01-14 17:03:48","TRT01EDTM":"2023-01-15 05:03:48","TRT02SDTM":"2023-01-15 05:03:48","TRT02EDTM":"2024-01-15 11:03:48","AP01SDTM":"2021-01-14 17:03:48","AP01EDTM":"2023-01-15 05:03:48","AP02SDTM":"2023-01-15 05:03:48","AP02EDTM":"2024-01-15 11:03:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5330,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92867,"AVALU":"g/L","BASE2":3.0439,"BASE":2.90751,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11523,"PCHG2":-3.78561,"CHG":0.02115,"PCHG":0.72758,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-07 17:03:48","ADY":570,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-277","SUBJID":"id-277","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.07227,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 17:03:48","TRTEDTM":"2024-01-15 11:03:48","TRT01SDTM":"2021-01-14 17:03:48","TRT01EDTM":"2023-01-15 05:03:48","TRT02SDTM":"2023-01-15 05:03:48","TRT02EDTM":"2024-01-15 11:03:48","AP01SDTM":"2021-01-14 17:03:48","AP01EDTM":"2023-01-15 05:03:48","AP02SDTM":"2023-01-15 05:03:48","AP02EDTM":"2024-01-15 11:03:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5788,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87052,"AVALU":"g/L","BASE2":3.0439,"BASE":2.90751,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17337,"PCHG2":-5.69582,"CHG":-0.03699,"PCHG":-1.27223,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-08 17:03:48","ADY":632,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-277","SUBJID":"id-277","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.07227,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 17:03:48","TRTEDTM":"2024-01-15 11:03:48","TRT01SDTM":"2021-01-14 17:03:48","TRT01EDTM":"2023-01-15 05:03:48","TRT02SDTM":"2023-01-15 05:03:48","TRT02EDTM":"2024-01-15 11:03:48","AP01SDTM":"2021-01-14 17:03:48","AP01EDTM":"2023-01-15 05:03:48","AP02SDTM":"2023-01-15 05:03:48","AP02EDTM":"2024-01-15 11:03:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1898,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02346,"AVALU":"g/L","BASE2":3.0439,"BASE":2.90751,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02043,"PCHG2":-0.67132,"CHG":0.11595,"PCHG":3.98795,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2023-02-02 17:03:48","ADY":749,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-277","SUBJID":"id-277","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.07227,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 17:03:48","TRTEDTM":"2024-01-15 11:03:48","TRT01SDTM":"2021-01-14 17:03:48","TRT01EDTM":"2023-01-15 05:03:48","TRT02SDTM":"2023-01-15 05:03:48","TRT02EDTM":"2024-01-15 11:03:48","AP01SDTM":"2021-01-14 17:03:48","AP01EDTM":"2023-01-15 05:03:48","AP02SDTM":"2023-01-15 05:03:48","AP02EDTM":"2024-01-15 11:03:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3830,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.73753,"AVALU":"g/L","BASE2":3.0439,"BASE":2.90751,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.30637,"PCHG2":-10.06499,"CHG":-0.16998,"PCHG":-5.84634,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-24 17:03:48","ADY":830,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-277","SUBJID":"id-277","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.07227,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 17:03:48","TRTEDTM":"2024-01-15 11:03:48","TRT01SDTM":"2021-01-14 17:03:48","TRT01EDTM":"2023-01-15 05:03:48","TRT02SDTM":"2023-01-15 05:03:48","TRT02EDTM":"2024-01-15 11:03:48","AP01SDTM":"2021-01-14 17:03:48","AP01EDTM":"2023-01-15 05:03:48","AP02SDTM":"2023-01-15 05:03:48","AP02EDTM":"2024-01-15 11:03:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6827,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05442,"AVALU":"g/L","BASE2":3.0439,"BASE":2.90751,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01052,"PCHG2":0.34559,"CHG":0.1469,"PCHG":5.05257,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2023-08-06 17:03:48","ADY":934,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-279","SUBJID":"id-279","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.64194,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-16","TRTSDTM":"2020-03-17 18:18:37","TRTEDTM":"2023-03-18 12:18:37","TRT01SDTM":"2020-03-17 18:18:37","TRT01EDTM":"2022-03-18 06:18:37","TRT02SDTM":"2022-03-18 06:18:37","TRT02EDTM":"2023-03-18 12:18:37","AP01SDTM":"2020-03-17 18:18:37","AP01EDTM":"2022-03-18 06:18:37","AP02SDTM":"2022-03-18 06:18:37","AP02EDTM":"2023-03-18 12:18:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-18","EOSDY":1096,"LSTALVDT":"2023-04-03","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7868,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.43428,"AVALU":"U/L","BASE2":6.43428,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-04-16 18:18:37","ADY":30,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-279","SUBJID":"id-279","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.64194,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-16","TRTSDTM":"2020-03-17 18:18:37","TRTEDTM":"2023-03-18 12:18:37","TRT01SDTM":"2020-03-17 18:18:37","TRT01EDTM":"2022-03-18 06:18:37","TRT02SDTM":"2022-03-18 06:18:37","TRT02EDTM":"2023-03-18 12:18:37","AP01SDTM":"2020-03-17 18:18:37","AP01EDTM":"2022-03-18 06:18:37","AP02SDTM":"2022-03-18 06:18:37","AP02EDTM":"2023-03-18 12:18:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-18","EOSDY":1096,"LSTALVDT":"2023-04-03","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":589,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.28576,"AVALU":"U/L","BASE2":6.43428,"BASE":31.28576,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":24.85149,"PCHG2":386.23593,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-03 18:18:37","ADY":351,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-279","SUBJID":"id-279","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.64194,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-16","TRTSDTM":"2020-03-17 18:18:37","TRTEDTM":"2023-03-18 12:18:37","TRT01SDTM":"2020-03-17 18:18:37","TRT01EDTM":"2022-03-18 06:18:37","TRT02SDTM":"2022-03-18 06:18:37","TRT02EDTM":"2023-03-18 12:18:37","AP01SDTM":"2020-03-17 18:18:37","AP01EDTM":"2022-03-18 06:18:37","AP02SDTM":"2022-03-18 06:18:37","AP02EDTM":"2023-03-18 12:18:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-18","EOSDY":1096,"LSTALVDT":"2023-04-03","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7899,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.65967,"AVALU":"U/L","BASE2":6.43428,"BASE":31.28576,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.22539,"PCHG2":221.08769,"CHG":-10.62609,"PCHG":-33.96463,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-19 18:18:37","ADY":581,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-279","SUBJID":"id-279","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.64194,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-16","TRTSDTM":"2020-03-17 18:18:37","TRTEDTM":"2023-03-18 12:18:37","TRT01SDTM":"2020-03-17 18:18:37","TRT01EDTM":"2022-03-18 06:18:37","TRT02SDTM":"2022-03-18 06:18:37","TRT02EDTM":"2023-03-18 12:18:37","AP01SDTM":"2020-03-17 18:18:37","AP01EDTM":"2022-03-18 06:18:37","AP02SDTM":"2022-03-18 06:18:37","AP02EDTM":"2023-03-18 12:18:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-18","EOSDY":1096,"LSTALVDT":"2023-04-03","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4166,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.632,"AVALU":"U/L","BASE2":6.43428,"BASE":31.28576,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":24.19772,"PCHG2":376.07524,"CHG":-0.65377,"PCHG":-2.08966,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-22 18:18:37","ADY":707,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-279","SUBJID":"id-279","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.64194,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-16","TRTSDTM":"2020-03-17 18:18:37","TRTEDTM":"2023-03-18 12:18:37","TRT01SDTM":"2020-03-17 18:18:37","TRT01EDTM":"2022-03-18 06:18:37","TRT02SDTM":"2022-03-18 06:18:37","TRT02EDTM":"2023-03-18 12:18:37","AP01SDTM":"2020-03-17 18:18:37","AP01EDTM":"2022-03-18 06:18:37","AP02SDTM":"2022-03-18 06:18:37","AP02EDTM":"2023-03-18 12:18:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-18","EOSDY":1096,"LSTALVDT":"2023-04-03","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7546,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.51075,"AVALU":"U/L","BASE2":6.43428,"BASE":31.28576,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.07647,"PCHG2":141.06442,"CHG":-15.77501,"PCHG":-50.42234,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-24 18:18:37","ADY":709,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-279","SUBJID":"id-279","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.64194,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-16","TRTSDTM":"2020-03-17 18:18:37","TRTEDTM":"2023-03-18 12:18:37","TRT01SDTM":"2020-03-17 18:18:37","TRT01EDTM":"2022-03-18 06:18:37","TRT02SDTM":"2022-03-18 06:18:37","TRT02EDTM":"2023-03-18 12:18:37","AP01SDTM":"2020-03-17 18:18:37","AP01EDTM":"2022-03-18 06:18:37","AP02SDTM":"2022-03-18 06:18:37","AP02EDTM":"2023-03-18 12:18:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-18","EOSDY":1096,"LSTALVDT":"2023-04-03","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5497,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.70633,"AVALU":"U/L","BASE2":6.43428,"BASE":31.28576,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.27205,"PCHG2":237.35459,"CHG":-9.57944,"PCHG":-30.61916,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-06 18:18:37","ADY":841,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-279","SUBJID":"id-279","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.64194,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-16","TRTSDTM":"2020-03-17 18:18:37","TRTEDTM":"2023-03-18 12:18:37","TRT01SDTM":"2020-03-17 18:18:37","TRT01EDTM":"2022-03-18 06:18:37","TRT02SDTM":"2022-03-18 06:18:37","TRT02EDTM":"2023-03-18 12:18:37","AP01SDTM":"2020-03-17 18:18:37","AP01EDTM":"2022-03-18 06:18:37","AP02SDTM":"2022-03-18 06:18:37","AP02EDTM":"2023-03-18 12:18:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-18","EOSDY":1096,"LSTALVDT":"2023-04-03","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6918,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.49511,"AVALU":"U/L","BASE2":6.43428,"BASE":31.28576,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.06083,"PCHG2":94.19601,"CHG":-18.79066,"PCHG":-60.06136,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-05 18:18:37","ADY":932,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-279","SUBJID":"id-279","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.64194,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-16","TRTSDTM":"2020-03-17 18:18:37","TRTEDTM":"2023-03-18 12:18:37","TRT01SDTM":"2020-03-17 18:18:37","TRT01EDTM":"2022-03-18 06:18:37","TRT02SDTM":"2022-03-18 06:18:37","TRT02EDTM":"2023-03-18 12:18:37","AP01SDTM":"2020-03-17 18:18:37","AP01EDTM":"2022-03-18 06:18:37","AP02SDTM":"2022-03-18 06:18:37","AP02EDTM":"2023-03-18 12:18:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-18","EOSDY":1096,"LSTALVDT":"2023-04-03","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7701,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.37855,"AVALU":"mg/L","BASE2":10.37855,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"2","ADTM":"2020-04-16 18:18:37","ADY":30,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-279","SUBJID":"id-279","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.64194,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-16","TRTSDTM":"2020-03-17 18:18:37","TRTEDTM":"2023-03-18 12:18:37","TRT01SDTM":"2020-03-17 18:18:37","TRT01EDTM":"2022-03-18 06:18:37","TRT02SDTM":"2022-03-18 06:18:37","TRT02EDTM":"2023-03-18 12:18:37","AP01SDTM":"2020-03-17 18:18:37","AP01EDTM":"2022-03-18 06:18:37","AP02SDTM":"2022-03-18 06:18:37","AP02EDTM":"2023-03-18 12:18:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-18","EOSDY":1096,"LSTALVDT":"2023-04-03","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":866,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.2486,"AVALU":"mg/L","BASE2":10.37855,"BASE":10.2486,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.12995,"PCHG2":-1.25209,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2021-03-03 18:18:37","ADY":351,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-279","SUBJID":"id-279","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.64194,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-16","TRTSDTM":"2020-03-17 18:18:37","TRTEDTM":"2023-03-18 12:18:37","TRT01SDTM":"2020-03-17 18:18:37","TRT01EDTM":"2022-03-18 06:18:37","TRT02SDTM":"2022-03-18 06:18:37","TRT02EDTM":"2023-03-18 12:18:37","AP01SDTM":"2020-03-17 18:18:37","AP01EDTM":"2022-03-18 06:18:37","AP02SDTM":"2022-03-18 06:18:37","AP02EDTM":"2023-03-18 12:18:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-18","EOSDY":1096,"LSTALVDT":"2023-04-03","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1279,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.76008,"AVALU":"mg/L","BASE2":10.37855,"BASE":10.2486,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.61848,"PCHG2":-15.59445,"CHG":-1.48853,"PCHG":-14.52422,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-10-19 18:18:37","ADY":581,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-279","SUBJID":"id-279","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.64194,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-16","TRTSDTM":"2020-03-17 18:18:37","TRTEDTM":"2023-03-18 12:18:37","TRT01SDTM":"2020-03-17 18:18:37","TRT01EDTM":"2022-03-18 06:18:37","TRT02SDTM":"2022-03-18 06:18:37","TRT02EDTM":"2023-03-18 12:18:37","AP01SDTM":"2020-03-17 18:18:37","AP01EDTM":"2022-03-18 06:18:37","AP02SDTM":"2022-03-18 06:18:37","AP02EDTM":"2023-03-18 12:18:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-18","EOSDY":1096,"LSTALVDT":"2023-04-03","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5864,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.92081,"AVALU":"mg/L","BASE2":10.37855,"BASE":10.2486,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.45774,"PCHG2":-4.41043,"CHG":-0.32779,"PCHG":-3.19839,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-02-22 18:18:37","ADY":707,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-279","SUBJID":"id-279","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.64194,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-16","TRTSDTM":"2020-03-17 18:18:37","TRTEDTM":"2023-03-18 12:18:37","TRT01SDTM":"2020-03-17 18:18:37","TRT01EDTM":"2022-03-18 06:18:37","TRT02SDTM":"2022-03-18 06:18:37","TRT02EDTM":"2023-03-18 12:18:37","AP01SDTM":"2020-03-17 18:18:37","AP01EDTM":"2022-03-18 06:18:37","AP02SDTM":"2022-03-18 06:18:37","AP02EDTM":"2023-03-18 12:18:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-18","EOSDY":1096,"LSTALVDT":"2023-04-03","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5337,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.83218,"AVALU":"mg/L","BASE2":10.37855,"BASE":10.2486,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.54637,"PCHG2":-14.89971,"CHG":-1.41643,"PCHG":-13.82067,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-02-24 18:18:37","ADY":709,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-279","SUBJID":"id-279","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.64194,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-16","TRTSDTM":"2020-03-17 18:18:37","TRTEDTM":"2023-03-18 12:18:37","TRT01SDTM":"2020-03-17 18:18:37","TRT01EDTM":"2022-03-18 06:18:37","TRT02SDTM":"2022-03-18 06:18:37","TRT02EDTM":"2023-03-18 12:18:37","AP01SDTM":"2020-03-17 18:18:37","AP01EDTM":"2022-03-18 06:18:37","AP02SDTM":"2022-03-18 06:18:37","AP02EDTM":"2023-03-18 12:18:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-18","EOSDY":1096,"LSTALVDT":"2023-04-03","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5303,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.62939,"AVALU":"mg/L","BASE2":10.37855,"BASE":10.2486,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.74917,"PCHG2":-16.85365,"CHG":-1.61922,"PCHG":-15.79938,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-07-06 18:18:37","ADY":841,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-279","SUBJID":"id-279","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.64194,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-16","TRTSDTM":"2020-03-17 18:18:37","TRTEDTM":"2023-03-18 12:18:37","TRT01SDTM":"2020-03-17 18:18:37","TRT01EDTM":"2022-03-18 06:18:37","TRT02SDTM":"2022-03-18 06:18:37","TRT02EDTM":"2023-03-18 12:18:37","AP01SDTM":"2020-03-17 18:18:37","AP01EDTM":"2022-03-18 06:18:37","AP02SDTM":"2022-03-18 06:18:37","AP02EDTM":"2023-03-18 12:18:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-18","EOSDY":1096,"LSTALVDT":"2023-04-03","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4010,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.58419,"AVALU":"mg/L","BASE2":10.37855,"BASE":10.2486,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.79436,"PCHG2":-26.92438,"CHG":-2.66441,"PCHG":-25.99781,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-2","BTOXGR":"2","ADTM":"2022-10-05 18:18:37","ADY":932,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-279","SUBJID":"id-279","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.64194,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-16","TRTSDTM":"2020-03-17 18:18:37","TRTEDTM":"2023-03-18 12:18:37","TRT01SDTM":"2020-03-17 18:18:37","TRT01EDTM":"2022-03-18 06:18:37","TRT02SDTM":"2022-03-18 06:18:37","TRT02EDTM":"2023-03-18 12:18:37","AP01SDTM":"2020-03-17 18:18:37","AP01EDTM":"2022-03-18 06:18:37","AP02SDTM":"2022-03-18 06:18:37","AP02EDTM":"2023-03-18 12:18:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-18","EOSDY":1096,"LSTALVDT":"2023-04-03","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4480,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96692,"AVALU":"g/L","BASE2":2.96692,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-16 18:18:37","ADY":30,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-279","SUBJID":"id-279","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.64194,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-16","TRTSDTM":"2020-03-17 18:18:37","TRTEDTM":"2023-03-18 12:18:37","TRT01SDTM":"2020-03-17 18:18:37","TRT01EDTM":"2022-03-18 06:18:37","TRT02SDTM":"2022-03-18 06:18:37","TRT02EDTM":"2023-03-18 12:18:37","AP01SDTM":"2020-03-17 18:18:37","AP01EDTM":"2022-03-18 06:18:37","AP02SDTM":"2022-03-18 06:18:37","AP02EDTM":"2023-03-18 12:18:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-18","EOSDY":1096,"LSTALVDT":"2023-04-03","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6583,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96641,"AVALU":"g/L","BASE2":2.96692,"BASE":2.96641,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.00051,"PCHG2":-0.0173,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-03 18:18:37","ADY":351,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-279","SUBJID":"id-279","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.64194,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-16","TRTSDTM":"2020-03-17 18:18:37","TRTEDTM":"2023-03-18 12:18:37","TRT01SDTM":"2020-03-17 18:18:37","TRT01EDTM":"2022-03-18 06:18:37","TRT02SDTM":"2022-03-18 06:18:37","TRT02EDTM":"2023-03-18 12:18:37","AP01SDTM":"2020-03-17 18:18:37","AP01EDTM":"2022-03-18 06:18:37","AP02SDTM":"2022-03-18 06:18:37","AP02EDTM":"2023-03-18 12:18:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-18","EOSDY":1096,"LSTALVDT":"2023-04-03","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7171,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05128,"AVALU":"g/L","BASE2":2.96692,"BASE":2.96641,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08435,"PCHG2":2.84311,"CHG":0.08487,"PCHG":2.86091,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-10-19 18:18:37","ADY":581,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-279","SUBJID":"id-279","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.64194,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-16","TRTSDTM":"2020-03-17 18:18:37","TRTEDTM":"2023-03-18 12:18:37","TRT01SDTM":"2020-03-17 18:18:37","TRT01EDTM":"2022-03-18 06:18:37","TRT02SDTM":"2022-03-18 06:18:37","TRT02EDTM":"2023-03-18 12:18:37","AP01SDTM":"2020-03-17 18:18:37","AP01EDTM":"2022-03-18 06:18:37","AP02SDTM":"2022-03-18 06:18:37","AP02EDTM":"2023-03-18 12:18:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-18","EOSDY":1096,"LSTALVDT":"2023-04-03","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3157,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92321,"AVALU":"g/L","BASE2":2.96692,"BASE":2.96641,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04371,"PCHG2":-1.47325,"CHG":-0.0432,"PCHG":-1.45621,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-22 18:18:37","ADY":707,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-279","SUBJID":"id-279","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.64194,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-16","TRTSDTM":"2020-03-17 18:18:37","TRTEDTM":"2023-03-18 12:18:37","TRT01SDTM":"2020-03-17 18:18:37","TRT01EDTM":"2022-03-18 06:18:37","TRT02SDTM":"2022-03-18 06:18:37","TRT02EDTM":"2023-03-18 12:18:37","AP01SDTM":"2020-03-17 18:18:37","AP01EDTM":"2022-03-18 06:18:37","AP02SDTM":"2022-03-18 06:18:37","AP02EDTM":"2023-03-18 12:18:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-18","EOSDY":1096,"LSTALVDT":"2023-04-03","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7362,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93946,"AVALU":"g/L","BASE2":2.96692,"BASE":2.96641,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02746,"PCHG2":-0.92565,"CHG":-0.02695,"PCHG":-0.90851,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-24 18:18:37","ADY":709,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-279","SUBJID":"id-279","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.64194,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-16","TRTSDTM":"2020-03-17 18:18:37","TRTEDTM":"2023-03-18 12:18:37","TRT01SDTM":"2020-03-17 18:18:37","TRT01EDTM":"2022-03-18 06:18:37","TRT02SDTM":"2022-03-18 06:18:37","TRT02EDTM":"2023-03-18 12:18:37","AP01SDTM":"2020-03-17 18:18:37","AP01EDTM":"2022-03-18 06:18:37","AP02SDTM":"2022-03-18 06:18:37","AP02EDTM":"2023-03-18 12:18:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-18","EOSDY":1096,"LSTALVDT":"2023-04-03","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8261,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91769,"AVALU":"g/L","BASE2":2.96692,"BASE":2.96641,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04923,"PCHG2":-1.65927,"CHG":-0.04872,"PCHG":-1.64225,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-06 18:18:37","ADY":841,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-279","SUBJID":"id-279","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.64194,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-16","TRTSDTM":"2020-03-17 18:18:37","TRTEDTM":"2023-03-18 12:18:37","TRT01SDTM":"2020-03-17 18:18:37","TRT01EDTM":"2022-03-18 06:18:37","TRT02SDTM":"2022-03-18 06:18:37","TRT02EDTM":"2023-03-18 12:18:37","AP01SDTM":"2020-03-17 18:18:37","AP01EDTM":"2022-03-18 06:18:37","AP02SDTM":"2022-03-18 06:18:37","AP02EDTM":"2023-03-18 12:18:37","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-18","EOSDY":1096,"LSTALVDT":"2023-04-03","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1128,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98594,"AVALU":"g/L","BASE2":2.96692,"BASE":2.96641,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01902,"PCHG2":0.64103,"CHG":0.01953,"PCHG":0.65844,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-05 18:18:37","ADY":932,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-287","SUBJID":"id-287","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.19352,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-19","TRTSDTM":"2019-11-23 12:45:59","TRT01SDTM":"2019-11-23 12:45:59","AP01SDTM":"2019-11-23 12:45:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":749,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.49181,"AVALU":"U/L","BASE2":10.49181,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-07 12:45:59","ADY":14,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-287","SUBJID":"id-287","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.19352,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-19","TRTSDTM":"2019-11-23 12:45:59","TRT01SDTM":"2019-11-23 12:45:59","AP01SDTM":"2019-11-23 12:45:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4134,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.31246,"AVALU":"U/L","BASE2":10.49181,"BASE":30.31246,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":19.82065,"PCHG2":188.91547,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-28 12:45:59","ADY":35,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-287","SUBJID":"id-287","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.19352,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-19","TRTSDTM":"2019-11-23 12:45:59","TRT01SDTM":"2019-11-23 12:45:59","AP01SDTM":"2019-11-23 12:45:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4701,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.92998,"AVALU":"U/L","BASE2":10.49181,"BASE":30.31246,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.56183,"PCHG2":-43.47987,"CHG":-24.38248,"PCHG":-80.43714,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-05-23 12:45:59","ADY":182,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-287","SUBJID":"id-287","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.19352,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-19","TRTSDTM":"2019-11-23 12:45:59","TRT01SDTM":"2019-11-23 12:45:59","AP01SDTM":"2019-11-23 12:45:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4338,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.30781,"AVALU":"U/L","BASE2":10.49181,"BASE":30.31246,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.184,"PCHG2":-49.40997,"CHG":-25.00465,"PCHG":-82.48968,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-06-01 12:45:59","ADY":191,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-287","SUBJID":"id-287","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.19352,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-19","TRTSDTM":"2019-11-23 12:45:59","TRT01SDTM":"2019-11-23 12:45:59","AP01SDTM":"2019-11-23 12:45:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6648,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.14674,"AVALU":"U/L","BASE2":10.49181,"BASE":30.31246,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":21.65493,"PCHG2":206.39841,"CHG":1.83428,"PCHG":6.05123,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-11 12:45:59","ADY":201,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-287","SUBJID":"id-287","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.19352,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-19","TRTSDTM":"2019-11-23 12:45:59","TRT01SDTM":"2019-11-23 12:45:59","AP01SDTM":"2019-11-23 12:45:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":735,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.88014,"AVALU":"U/L","BASE2":10.49181,"BASE":30.31246,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.61167,"PCHG2":-72.54871,"CHG":-27.43233,"PCHG":-90.49851,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-04-21 12:45:59","ADY":515,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-287","SUBJID":"id-287","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.19352,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-19","TRTSDTM":"2019-11-23 12:45:59","TRT01SDTM":"2019-11-23 12:45:59","AP01SDTM":"2019-11-23 12:45:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5617,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.60551,"AVALU":"U/L","BASE2":10.49181,"BASE":30.31246,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.8863,"PCHG2":-17.97876,"CHG":-21.70695,"PCHG":-71.61064,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-25 12:45:59","ADY":519,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-287","SUBJID":"id-287","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.19352,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-19","TRTSDTM":"2019-11-23 12:45:59","TRT01SDTM":"2019-11-23 12:45:59","AP01SDTM":"2019-11-23 12:45:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":121,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.686,"AVALU":"mg/L","BASE2":10.686,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"2","BTOXGR":"0","ADTM":"2019-12-07 12:45:59","ADY":14,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-287","SUBJID":"id-287","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.19352,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-19","TRTSDTM":"2019-11-23 12:45:59","TRT01SDTM":"2019-11-23 12:45:59","AP01SDTM":"2019-11-23 12:45:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4822,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.16204,"AVALU":"mg/L","BASE2":10.686,"BASE":9.16204,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.52396,"PCHG2":-14.26125,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-28 12:45:59","ADY":35,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-287","SUBJID":"id-287","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.19352,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-19","TRTSDTM":"2019-11-23 12:45:59","TRT01SDTM":"2019-11-23 12:45:59","AP01SDTM":"2019-11-23 12:45:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4408,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.11429,"AVALU":"mg/L","BASE2":10.686,"BASE":9.16204,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.42829,"PCHG2":4.00793,"CHG":1.95224,"PCHG":21.30796,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-05-23 12:45:59","ADY":182,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-287","SUBJID":"id-287","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.19352,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-19","TRTSDTM":"2019-11-23 12:45:59","TRT01SDTM":"2019-11-23 12:45:59","AP01SDTM":"2019-11-23 12:45:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5294,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.79804,"AVALU":"mg/L","BASE2":10.686,"BASE":9.16204,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.88796,"PCHG2":-8.30959,"CHG":0.63599,"PCHG":6.94163,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-01 12:45:59","ADY":191,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-287","SUBJID":"id-287","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.19352,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-19","TRTSDTM":"2019-11-23 12:45:59","TRT01SDTM":"2019-11-23 12:45:59","AP01SDTM":"2019-11-23 12:45:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4565,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.52744,"AVALU":"mg/L","BASE2":10.686,"BASE":9.16204,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.15856,"PCHG2":-10.84182,"CHG":0.3654,"PCHG":3.9882,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-11 12:45:59","ADY":201,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-287","SUBJID":"id-287","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.19352,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-19","TRTSDTM":"2019-11-23 12:45:59","TRT01SDTM":"2019-11-23 12:45:59","AP01SDTM":"2019-11-23 12:45:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4672,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.77669,"AVALU":"mg/L","BASE2":10.686,"BASE":9.16204,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.90931,"PCHG2":-27.22543,"CHG":-1.38535,"PCHG":-15.12056,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-04-21 12:45:59","ADY":515,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-287","SUBJID":"id-287","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.19352,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-19","TRTSDTM":"2019-11-23 12:45:59","TRT01SDTM":"2019-11-23 12:45:59","AP01SDTM":"2019-11-23 12:45:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2911,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.61384,"AVALU":"mg/L","BASE2":10.686,"BASE":9.16204,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.07216,"PCHG2":-19.39139,"CHG":-0.54821,"PCHG":-5.98345,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-25 12:45:59","ADY":519,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-287","SUBJID":"id-287","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.19352,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-19","TRTSDTM":"2019-11-23 12:45:59","TRT01SDTM":"2019-11-23 12:45:59","AP01SDTM":"2019-11-23 12:45:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2573,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01913,"AVALU":"g/L","BASE2":3.01913,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2019-12-07 12:45:59","ADY":14,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-287","SUBJID":"id-287","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.19352,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-19","TRTSDTM":"2019-11-23 12:45:59","TRT01SDTM":"2019-11-23 12:45:59","AP01SDTM":"2019-11-23 12:45:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3410,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.11153,"AVALU":"g/L","BASE2":3.01913,"BASE":3.11153,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.0924,"PCHG2":3.06039,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2019-12-28 12:45:59","ADY":35,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-287","SUBJID":"id-287","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.19352,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-19","TRTSDTM":"2019-11-23 12:45:59","TRT01SDTM":"2019-11-23 12:45:59","AP01SDTM":"2019-11-23 12:45:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2575,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8206,"AVALU":"g/L","BASE2":3.01913,"BASE":3.11153,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19853,"PCHG2":-6.57571,"CHG":-0.29093,"PCHG":-9.34996,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-05-23 12:45:59","ADY":182,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-287","SUBJID":"id-287","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.19352,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-19","TRTSDTM":"2019-11-23 12:45:59","TRT01SDTM":"2019-11-23 12:45:59","AP01SDTM":"2019-11-23 12:45:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8379,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90855,"AVALU":"g/L","BASE2":3.01913,"BASE":3.11153,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11058,"PCHG2":-3.66277,"CHG":-0.20298,"PCHG":-6.52352,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-06-01 12:45:59","ADY":191,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-287","SUBJID":"id-287","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.19352,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-19","TRTSDTM":"2019-11-23 12:45:59","TRT01SDTM":"2019-11-23 12:45:59","AP01SDTM":"2019-11-23 12:45:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2484,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85567,"AVALU":"g/L","BASE2":3.01913,"BASE":3.11153,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16346,"PCHG2":-5.41421,"CHG":-0.25586,"PCHG":-8.22295,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-06-11 12:45:59","ADY":201,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-287","SUBJID":"id-287","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.19352,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-19","TRTSDTM":"2019-11-23 12:45:59","TRT01SDTM":"2019-11-23 12:45:59","AP01SDTM":"2019-11-23 12:45:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4674,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.08465,"AVALU":"g/L","BASE2":3.01913,"BASE":3.11153,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06552,"PCHG2":2.17026,"CHG":-0.02687,"PCHG":-0.8637,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"3","ADTM":"2021-04-21 12:45:59","ADY":515,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-287","SUBJID":"id-287","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.19352,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-19","TRTSDTM":"2019-11-23 12:45:59","TRT01SDTM":"2019-11-23 12:45:59","AP01SDTM":"2019-11-23 12:45:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6955,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88687,"AVALU":"g/L","BASE2":3.01913,"BASE":3.11153,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13226,"PCHG2":-4.38072,"CHG":-0.22466,"PCHG":-7.22014,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-04-25 12:45:59","ADY":519,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-288","SUBJID":"id-288","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.58264,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-09","TRTSDTM":"2019-12-11 09:17:03","TRT01SDTM":"2019-12-11 09:17:03","AP01SDTM":"2019-12-11 09:17:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7064,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.81932,"AVALU":"U/L","BASE2":14.81932,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-02 09:17:03","ADY":174,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-288","SUBJID":"id-288","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.58264,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-09","TRTSDTM":"2019-12-11 09:17:03","TRT01SDTM":"2019-12-11 09:17:03","AP01SDTM":"2019-12-11 09:17:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2253,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.68157,"AVALU":"U/L","BASE2":14.81932,"BASE":18.68157,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":3.86225,"PCHG2":26.06226,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-02 09:17:03","ADY":327,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-288","SUBJID":"id-288","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.58264,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-09","TRTSDTM":"2019-12-11 09:17:03","TRT01SDTM":"2019-12-11 09:17:03","AP01SDTM":"2019-12-11 09:17:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":421,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.45679,"AVALU":"U/L","BASE2":14.81932,"BASE":18.68157,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.63747,"PCHG2":71.78112,"CHG":6.77522,"PCHG":36.26688,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-13 09:17:03","ADY":368,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-288","SUBJID":"id-288","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.58264,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-09","TRTSDTM":"2019-12-11 09:17:03","TRT01SDTM":"2019-12-11 09:17:03","AP01SDTM":"2019-12-11 09:17:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3848,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.77056,"AVALU":"U/L","BASE2":14.81932,"BASE":18.68157,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.95125,"PCHG2":67.1505,"CHG":6.089,"PCHG":32.59361,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-03 09:17:03","ADY":479,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-288","SUBJID":"id-288","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.58264,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-09","TRTSDTM":"2019-12-11 09:17:03","TRT01SDTM":"2019-12-11 09:17:03","AP01SDTM":"2019-12-11 09:17:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2961,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.67397,"AVALU":"U/L","BASE2":14.81932,"BASE":18.68157,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.85466,"PCHG2":127.23026,"CHG":14.99241,"PCHG":80.25241,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-23 09:17:03","ADY":499,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-288","SUBJID":"id-288","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.58264,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-09","TRTSDTM":"2019-12-11 09:17:03","TRT01SDTM":"2019-12-11 09:17:03","AP01SDTM":"2019-12-11 09:17:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1345,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.86757,"AVALU":"U/L","BASE2":14.81932,"BASE":18.68157,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.04826,"PCHG2":27.31744,"CHG":0.18601,"PCHG":0.99568,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-29 09:17:03","ADY":535,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-288","SUBJID":"id-288","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.58264,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-09","TRTSDTM":"2019-12-11 09:17:03","TRT01SDTM":"2019-12-11 09:17:03","AP01SDTM":"2019-12-11 09:17:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6834,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.82815,"AVALU":"U/L","BASE2":14.81932,"BASE":18.68157,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.99116,"PCHG2":-94.41167,"CHG":-17.85341,"PCHG":-95.56701,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-07-07 09:17:03","ADY":574,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-288","SUBJID":"id-288","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.58264,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-09","TRTSDTM":"2019-12-11 09:17:03","TRT01SDTM":"2019-12-11 09:17:03","AP01SDTM":"2019-12-11 09:17:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5774,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.6043,"AVALU":"mg/L","BASE2":8.6043,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-02 09:17:03","ADY":174,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-288","SUBJID":"id-288","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.58264,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-09","TRTSDTM":"2019-12-11 09:17:03","TRT01SDTM":"2019-12-11 09:17:03","AP01SDTM":"2019-12-11 09:17:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":201,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.22237,"AVALU":"mg/L","BASE2":8.6043,"BASE":8.22237,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.38193,"PCHG2":-4.43882,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-02 09:17:03","ADY":327,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-288","SUBJID":"id-288","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.58264,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-09","TRTSDTM":"2019-12-11 09:17:03","TRT01SDTM":"2019-12-11 09:17:03","AP01SDTM":"2019-12-11 09:17:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3946,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.00551,"AVALU":"mg/L","BASE2":8.6043,"BASE":8.22237,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.59879,"PCHG2":-6.95918,"CHG":-0.21686,"PCHG":-2.63743,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-13 09:17:03","ADY":368,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-288","SUBJID":"id-288","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.58264,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-09","TRTSDTM":"2019-12-11 09:17:03","TRT01SDTM":"2019-12-11 09:17:03","AP01SDTM":"2019-12-11 09:17:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6143,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.07788,"AVALU":"mg/L","BASE2":8.6043,"BASE":8.22237,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.47358,"PCHG2":5.50399,"CHG":0.85551,"PCHG":10.40465,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-03 09:17:03","ADY":479,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-288","SUBJID":"id-288","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.58264,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-09","TRTSDTM":"2019-12-11 09:17:03","TRT01SDTM":"2019-12-11 09:17:03","AP01SDTM":"2019-12-11 09:17:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":290,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.62763,"AVALU":"mg/L","BASE2":8.6043,"BASE":8.22237,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.02333,"PCHG2":11.89327,"CHG":1.40526,"PCHG":17.09071,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-23 09:17:03","ADY":499,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-288","SUBJID":"id-288","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.58264,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-09","TRTSDTM":"2019-12-11 09:17:03","TRT01SDTM":"2019-12-11 09:17:03","AP01SDTM":"2019-12-11 09:17:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1397,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.50429,"AVALU":"mg/L","BASE2":8.6043,"BASE":8.22237,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10001,"PCHG2":-1.16231,"CHG":0.28192,"PCHG":3.4287,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-29 09:17:03","ADY":535,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-288","SUBJID":"id-288","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.58264,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-09","TRTSDTM":"2019-12-11 09:17:03","TRT01SDTM":"2019-12-11 09:17:03","AP01SDTM":"2019-12-11 09:17:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6826,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.29312,"AVALU":"mg/L","BASE2":8.6043,"BASE":8.22237,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.68882,"PCHG2":8.00553,"CHG":1.07075,"PCHG":13.02239,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-07 09:17:03","ADY":574,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-288","SUBJID":"id-288","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.58264,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-09","TRTSDTM":"2019-12-11 09:17:03","TRT01SDTM":"2019-12-11 09:17:03","AP01SDTM":"2019-12-11 09:17:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3903,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88337,"AVALU":"g/L","BASE2":2.88337,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-02 09:17:03","ADY":174,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-288","SUBJID":"id-288","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.58264,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-09","TRTSDTM":"2019-12-11 09:17:03","TRT01SDTM":"2019-12-11 09:17:03","AP01SDTM":"2019-12-11 09:17:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4783,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95998,"AVALU":"g/L","BASE2":2.88337,"BASE":2.95998,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.07661,"PCHG2":2.65693,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-02 09:17:03","ADY":327,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-288","SUBJID":"id-288","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.58264,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-09","TRTSDTM":"2019-12-11 09:17:03","TRT01SDTM":"2019-12-11 09:17:03","AP01SDTM":"2019-12-11 09:17:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3126,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05536,"AVALU":"g/L","BASE2":2.88337,"BASE":2.95998,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17199,"PCHG2":5.96486,"CHG":0.09538,"PCHG":3.22232,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-12-13 09:17:03","ADY":368,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-288","SUBJID":"id-288","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.58264,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-09","TRTSDTM":"2019-12-11 09:17:03","TRT01SDTM":"2019-12-11 09:17:03","AP01SDTM":"2019-12-11 09:17:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":609,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03698,"AVALU":"g/L","BASE2":2.88337,"BASE":2.95998,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1536,"PCHG2":5.32723,"CHG":0.07699,"PCHG":2.60119,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-04-03 09:17:03","ADY":479,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-288","SUBJID":"id-288","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.58264,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-09","TRTSDTM":"2019-12-11 09:17:03","TRT01SDTM":"2019-12-11 09:17:03","AP01SDTM":"2019-12-11 09:17:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7321,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91181,"AVALU":"g/L","BASE2":2.88337,"BASE":2.95998,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02844,"PCHG2":0.98642,"CHG":-0.04817,"PCHG":-1.62728,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-23 09:17:03","ADY":499,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-288","SUBJID":"id-288","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.58264,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-09","TRTSDTM":"2019-12-11 09:17:03","TRT01SDTM":"2019-12-11 09:17:03","AP01SDTM":"2019-12-11 09:17:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":724,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85324,"AVALU":"g/L","BASE2":2.88337,"BASE":2.95998,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03013,"PCHG2":-1.04492,"CHG":-0.10674,"PCHG":-3.60604,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-29 09:17:03","ADY":535,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-288","SUBJID":"id-288","SITEID":"CHN-1","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.58264,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-09","TRTSDTM":"2019-12-11 09:17:03","TRT01SDTM":"2019-12-11 09:17:03","AP01SDTM":"2019-12-11 09:17:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6040,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.67821,"AVALU":"g/L","BASE2":2.88337,"BASE":2.95998,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20516,"PCHG2":-7.11536,"CHG":-0.28177,"PCHG":-9.51937,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-07 09:17:03","ADY":574,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-307","SUBJID":"id-307","SITEID":"CHN-1","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57499,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-08","TRTSDTM":"2019-03-11 08:01:26","TRTEDTM":"2022-02-18 08:48:40","TRT01SDTM":"2019-03-11 08:01:26","TRT01EDTM":"2021-02-18 02:48:40","TRT02SDTM":"2021-02-18 02:48:40","TRT02EDTM":"2022-02-18 08:48:40","AP01SDTM":"2019-03-11 08:01:26","AP01EDTM":"2021-02-18 02:48:40","AP02SDTM":"2021-02-18 02:48:40","AP02EDTM":"2022-02-18 08:48:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1076,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":1121,"ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":974,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.94612,"AVALU":"U/L","BASE2":14.94612,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-11 08:01:26","ADY":122,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-307","SUBJID":"id-307","SITEID":"CHN-1","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57499,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-08","TRTSDTM":"2019-03-11 08:01:26","TRTEDTM":"2022-02-18 08:48:40","TRT01SDTM":"2019-03-11 08:01:26","TRT01EDTM":"2021-02-18 02:48:40","TRT02SDTM":"2021-02-18 02:48:40","TRT02EDTM":"2022-02-18 08:48:40","AP01SDTM":"2019-03-11 08:01:26","AP01EDTM":"2021-02-18 02:48:40","AP02SDTM":"2021-02-18 02:48:40","AP02EDTM":"2022-02-18 08:48:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1076,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":1121,"ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1316,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.98719,"AVALU":"U/L","BASE2":14.94612,"BASE":31.98719,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":17.04107,"PCHG2":114.01673,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-11 08:01:26","ADY":153,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-307","SUBJID":"id-307","SITEID":"CHN-1","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57499,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-08","TRTSDTM":"2019-03-11 08:01:26","TRTEDTM":"2022-02-18 08:48:40","TRT01SDTM":"2019-03-11 08:01:26","TRT01EDTM":"2021-02-18 02:48:40","TRT02SDTM":"2021-02-18 02:48:40","TRT02EDTM":"2022-02-18 08:48:40","AP01SDTM":"2019-03-11 08:01:26","AP01EDTM":"2021-02-18 02:48:40","AP02SDTM":"2021-02-18 02:48:40","AP02EDTM":"2022-02-18 08:48:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1076,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":1121,"ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2019,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.2801,"AVALU":"U/L","BASE2":14.94612,"BASE":31.98719,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.33398,"PCHG2":22.30669,"CHG":-13.70709,"PCHG":-42.85181,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-13 08:01:26","ADY":277,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-307","SUBJID":"id-307","SITEID":"CHN-1","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57499,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-08","TRTSDTM":"2019-03-11 08:01:26","TRTEDTM":"2022-02-18 08:48:40","TRT01SDTM":"2019-03-11 08:01:26","TRT01EDTM":"2021-02-18 02:48:40","TRT02SDTM":"2021-02-18 02:48:40","TRT02EDTM":"2022-02-18 08:48:40","AP01SDTM":"2019-03-11 08:01:26","AP01EDTM":"2021-02-18 02:48:40","AP02SDTM":"2021-02-18 02:48:40","AP02EDTM":"2022-02-18 08:48:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1076,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":1121,"ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1985,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.52659,"AVALU":"U/L","BASE2":14.94612,"BASE":31.98719,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.58047,"PCHG2":3.88376,"CHG":-16.4606,"PCHG":-51.45998,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-16 08:01:26","ADY":402,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-307","SUBJID":"id-307","SITEID":"CHN-1","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57499,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-08","TRTSDTM":"2019-03-11 08:01:26","TRTEDTM":"2022-02-18 08:48:40","TRT01SDTM":"2019-03-11 08:01:26","TRT01EDTM":"2021-02-18 02:48:40","TRT02SDTM":"2021-02-18 02:48:40","TRT02EDTM":"2022-02-18 08:48:40","AP01SDTM":"2019-03-11 08:01:26","AP01EDTM":"2021-02-18 02:48:40","AP02SDTM":"2021-02-18 02:48:40","AP02EDTM":"2022-02-18 08:48:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1076,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":1121,"ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4613,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.392,"AVALU":"U/L","BASE2":14.94612,"BASE":31.98719,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.44589,"PCHG2":36.43681,"CHG":-11.59519,"PCHG":-36.24947,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-02 08:01:26","ADY":510,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-307","SUBJID":"id-307","SITEID":"CHN-1","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57499,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-08","TRTSDTM":"2019-03-11 08:01:26","TRTEDTM":"2022-02-18 08:48:40","TRT01SDTM":"2019-03-11 08:01:26","TRT01EDTM":"2021-02-18 02:48:40","TRT02SDTM":"2021-02-18 02:48:40","TRT02EDTM":"2022-02-18 08:48:40","AP01SDTM":"2019-03-11 08:01:26","AP01EDTM":"2021-02-18 02:48:40","AP02SDTM":"2021-02-18 02:48:40","AP02EDTM":"2022-02-18 08:48:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1076,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":1121,"ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6015,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.85622,"AVALU":"U/L","BASE2":14.94612,"BASE":31.98719,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.91011,"PCHG2":32.85207,"CHG":-12.13096,"PCHG":-37.92445,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-24 08:01:26","ADY":593,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-307","SUBJID":"id-307","SITEID":"CHN-1","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57499,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-08","TRTSDTM":"2019-03-11 08:01:26","TRTEDTM":"2022-02-18 08:48:40","TRT01SDTM":"2019-03-11 08:01:26","TRT01EDTM":"2021-02-18 02:48:40","TRT02SDTM":"2021-02-18 02:48:40","TRT02EDTM":"2022-02-18 08:48:40","AP01SDTM":"2019-03-11 08:01:26","AP01EDTM":"2021-02-18 02:48:40","AP02SDTM":"2021-02-18 02:48:40","AP02EDTM":"2022-02-18 08:48:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1076,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":1121,"ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1083,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.54643,"AVALU":"U/L","BASE2":14.94612,"BASE":31.98719,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.60031,"PCHG2":24.08862,"CHG":-13.44076,"PCHG":-42.0192,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-08 08:01:26","ADY":820,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-307","SUBJID":"id-307","SITEID":"CHN-1","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57499,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-08","TRTSDTM":"2019-03-11 08:01:26","TRTEDTM":"2022-02-18 08:48:40","TRT01SDTM":"2019-03-11 08:01:26","TRT01EDTM":"2021-02-18 02:48:40","TRT02SDTM":"2021-02-18 02:48:40","TRT02EDTM":"2022-02-18 08:48:40","AP01SDTM":"2019-03-11 08:01:26","AP01EDTM":"2021-02-18 02:48:40","AP02SDTM":"2021-02-18 02:48:40","AP02EDTM":"2022-02-18 08:48:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1076,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":1121,"ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7615,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.07756,"AVALU":"mg/L","BASE2":8.07756,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2019-07-11 08:01:26","ADY":122,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-307","SUBJID":"id-307","SITEID":"CHN-1","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57499,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-08","TRTSDTM":"2019-03-11 08:01:26","TRTEDTM":"2022-02-18 08:48:40","TRT01SDTM":"2019-03-11 08:01:26","TRT01EDTM":"2021-02-18 02:48:40","TRT02SDTM":"2021-02-18 02:48:40","TRT02EDTM":"2022-02-18 08:48:40","AP01SDTM":"2019-03-11 08:01:26","AP01EDTM":"2021-02-18 02:48:40","AP02SDTM":"2021-02-18 02:48:40","AP02EDTM":"2022-02-18 08:48:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1076,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":1121,"ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5593,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.25932,"AVALU":"mg/L","BASE2":8.07756,"BASE":10.25932,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.18176,"PCHG2":27.01014,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2019-08-11 08:01:26","ADY":153,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-307","SUBJID":"id-307","SITEID":"CHN-1","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57499,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-08","TRTSDTM":"2019-03-11 08:01:26","TRTEDTM":"2022-02-18 08:48:40","TRT01SDTM":"2019-03-11 08:01:26","TRT01EDTM":"2021-02-18 02:48:40","TRT02SDTM":"2021-02-18 02:48:40","TRT02EDTM":"2022-02-18 08:48:40","AP01SDTM":"2019-03-11 08:01:26","AP01EDTM":"2021-02-18 02:48:40","AP02SDTM":"2021-02-18 02:48:40","AP02EDTM":"2022-02-18 08:48:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1076,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":1121,"ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3586,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.73377,"AVALU":"mg/L","BASE2":8.07756,"BASE":10.25932,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.65622,"PCHG2":8.12394,"CHG":-1.52554,"PCHG":-14.86984,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2019-12-13 08:01:26","ADY":277,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-307","SUBJID":"id-307","SITEID":"CHN-1","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57499,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-08","TRTSDTM":"2019-03-11 08:01:26","TRTEDTM":"2022-02-18 08:48:40","TRT01SDTM":"2019-03-11 08:01:26","TRT01EDTM":"2021-02-18 02:48:40","TRT02SDTM":"2021-02-18 02:48:40","TRT02EDTM":"2022-02-18 08:48:40","AP01SDTM":"2019-03-11 08:01:26","AP01EDTM":"2021-02-18 02:48:40","AP02SDTM":"2021-02-18 02:48:40","AP02EDTM":"2022-02-18 08:48:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1076,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":1121,"ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8236,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.72551,"AVALU":"mg/L","BASE2":8.07756,"BASE":10.25932,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.64796,"PCHG2":8.02167,"CHG":-1.53381,"PCHG":-14.95036,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-04-16 08:01:26","ADY":402,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-307","SUBJID":"id-307","SITEID":"CHN-1","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57499,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-08","TRTSDTM":"2019-03-11 08:01:26","TRTEDTM":"2022-02-18 08:48:40","TRT01SDTM":"2019-03-11 08:01:26","TRT01EDTM":"2021-02-18 02:48:40","TRT02SDTM":"2021-02-18 02:48:40","TRT02EDTM":"2022-02-18 08:48:40","AP01SDTM":"2019-03-11 08:01:26","AP01EDTM":"2021-02-18 02:48:40","AP02SDTM":"2021-02-18 02:48:40","AP02EDTM":"2022-02-18 08:48:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1076,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":1121,"ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5605,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.243,"AVALU":"mg/L","BASE2":8.07756,"BASE":10.25932,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.16544,"PCHG2":26.80809,"CHG":-0.01632,"PCHG":-0.15908,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"3","ADTM":"2020-08-02 08:01:26","ADY":510,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-307","SUBJID":"id-307","SITEID":"CHN-1","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57499,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-08","TRTSDTM":"2019-03-11 08:01:26","TRTEDTM":"2022-02-18 08:48:40","TRT01SDTM":"2019-03-11 08:01:26","TRT01EDTM":"2021-02-18 02:48:40","TRT02SDTM":"2021-02-18 02:48:40","TRT02EDTM":"2022-02-18 08:48:40","AP01SDTM":"2019-03-11 08:01:26","AP01EDTM":"2021-02-18 02:48:40","AP02SDTM":"2021-02-18 02:48:40","AP02EDTM":"2022-02-18 08:48:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1076,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":1121,"ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2916,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.23117,"AVALU":"mg/L","BASE2":8.07756,"BASE":10.25932,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.15362,"PCHG2":14.28175,"CHG":-1.02814,"PCHG":-10.02155,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-10-24 08:01:26","ADY":593,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-307","SUBJID":"id-307","SITEID":"CHN-1","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57499,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-08","TRTSDTM":"2019-03-11 08:01:26","TRTEDTM":"2022-02-18 08:48:40","TRT01SDTM":"2019-03-11 08:01:26","TRT01EDTM":"2021-02-18 02:48:40","TRT02SDTM":"2021-02-18 02:48:40","TRT02EDTM":"2022-02-18 08:48:40","AP01SDTM":"2019-03-11 08:01:26","AP01EDTM":"2021-02-18 02:48:40","AP02SDTM":"2021-02-18 02:48:40","AP02EDTM":"2022-02-18 08:48:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1076,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":1121,"ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7529,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.4133,"AVALU":"mg/L","BASE2":8.07756,"BASE":10.25932,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.33574,"PCHG2":28.91642,"CHG":0.15398,"PCHG":1.50088,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"1","BTOXGR":"3","ADTM":"2021-06-08 08:01:26","ADY":820,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-307","SUBJID":"id-307","SITEID":"CHN-1","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57499,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-08","TRTSDTM":"2019-03-11 08:01:26","TRTEDTM":"2022-02-18 08:48:40","TRT01SDTM":"2019-03-11 08:01:26","TRT01EDTM":"2021-02-18 02:48:40","TRT02SDTM":"2021-02-18 02:48:40","TRT02EDTM":"2022-02-18 08:48:40","AP01SDTM":"2019-03-11 08:01:26","AP01EDTM":"2021-02-18 02:48:40","AP02SDTM":"2021-02-18 02:48:40","AP02EDTM":"2022-02-18 08:48:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1076,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":1121,"ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8109,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96304,"AVALU":"g/L","BASE2":2.96304,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-11 08:01:26","ADY":122,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-307","SUBJID":"id-307","SITEID":"CHN-1","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57499,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-08","TRTSDTM":"2019-03-11 08:01:26","TRTEDTM":"2022-02-18 08:48:40","TRT01SDTM":"2019-03-11 08:01:26","TRT01EDTM":"2021-02-18 02:48:40","TRT02SDTM":"2021-02-18 02:48:40","TRT02EDTM":"2022-02-18 08:48:40","AP01SDTM":"2019-03-11 08:01:26","AP01EDTM":"2021-02-18 02:48:40","AP02SDTM":"2021-02-18 02:48:40","AP02EDTM":"2022-02-18 08:48:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1076,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":1121,"ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4359,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7674,"AVALU":"g/L","BASE2":2.96304,"BASE":2.7674,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.19564,"PCHG2":-6.60263,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-11 08:01:26","ADY":153,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-307","SUBJID":"id-307","SITEID":"CHN-1","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57499,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-08","TRTSDTM":"2019-03-11 08:01:26","TRTEDTM":"2022-02-18 08:48:40","TRT01SDTM":"2019-03-11 08:01:26","TRT01EDTM":"2021-02-18 02:48:40","TRT02SDTM":"2021-02-18 02:48:40","TRT02EDTM":"2022-02-18 08:48:40","AP01SDTM":"2019-03-11 08:01:26","AP01EDTM":"2021-02-18 02:48:40","AP02SDTM":"2021-02-18 02:48:40","AP02EDTM":"2022-02-18 08:48:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1076,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":1121,"ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6598,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97305,"AVALU":"g/L","BASE2":2.96304,"BASE":2.7674,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01001,"PCHG2":0.33786,"CHG":0.20565,"PCHG":7.43115,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-13 08:01:26","ADY":277,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-307","SUBJID":"id-307","SITEID":"CHN-1","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57499,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-08","TRTSDTM":"2019-03-11 08:01:26","TRTEDTM":"2022-02-18 08:48:40","TRT01SDTM":"2019-03-11 08:01:26","TRT01EDTM":"2021-02-18 02:48:40","TRT02SDTM":"2021-02-18 02:48:40","TRT02EDTM":"2022-02-18 08:48:40","AP01SDTM":"2019-03-11 08:01:26","AP01EDTM":"2021-02-18 02:48:40","AP02SDTM":"2021-02-18 02:48:40","AP02EDTM":"2022-02-18 08:48:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1076,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":1121,"ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3372,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02889,"AVALU":"g/L","BASE2":2.96304,"BASE":2.7674,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06585,"PCHG2":2.22251,"CHG":0.26149,"PCHG":9.44903,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-04-16 08:01:26","ADY":402,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-307","SUBJID":"id-307","SITEID":"CHN-1","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57499,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-08","TRTSDTM":"2019-03-11 08:01:26","TRTEDTM":"2022-02-18 08:48:40","TRT01SDTM":"2019-03-11 08:01:26","TRT01EDTM":"2021-02-18 02:48:40","TRT02SDTM":"2021-02-18 02:48:40","TRT02EDTM":"2022-02-18 08:48:40","AP01SDTM":"2019-03-11 08:01:26","AP01EDTM":"2021-02-18 02:48:40","AP02SDTM":"2021-02-18 02:48:40","AP02EDTM":"2022-02-18 08:48:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1076,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":1121,"ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3887,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94772,"AVALU":"g/L","BASE2":2.96304,"BASE":2.7674,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01532,"PCHG2":-0.51712,"CHG":0.18032,"PCHG":6.51573,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-02 08:01:26","ADY":510,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-307","SUBJID":"id-307","SITEID":"CHN-1","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57499,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-08","TRTSDTM":"2019-03-11 08:01:26","TRTEDTM":"2022-02-18 08:48:40","TRT01SDTM":"2019-03-11 08:01:26","TRT01EDTM":"2021-02-18 02:48:40","TRT02SDTM":"2021-02-18 02:48:40","TRT02EDTM":"2022-02-18 08:48:40","AP01SDTM":"2019-03-11 08:01:26","AP01EDTM":"2021-02-18 02:48:40","AP02SDTM":"2021-02-18 02:48:40","AP02EDTM":"2022-02-18 08:48:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1076,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":1121,"ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3082,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95776,"AVALU":"g/L","BASE2":2.96304,"BASE":2.7674,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00528,"PCHG2":-0.17823,"CHG":0.19036,"PCHG":6.87857,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-24 08:01:26","ADY":593,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-307","SUBJID":"id-307","SITEID":"CHN-1","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57499,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-08","TRTSDTM":"2019-03-11 08:01:26","TRTEDTM":"2022-02-18 08:48:40","TRT01SDTM":"2019-03-11 08:01:26","TRT01EDTM":"2021-02-18 02:48:40","TRT02SDTM":"2021-02-18 02:48:40","TRT02EDTM":"2022-02-18 08:48:40","AP01SDTM":"2019-03-11 08:01:26","AP01EDTM":"2021-02-18 02:48:40","AP02SDTM":"2021-02-18 02:48:40","AP02EDTM":"2022-02-18 08:48:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1076,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":47,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":1121,"ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7105,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95447,"AVALU":"g/L","BASE2":2.96304,"BASE":2.7674,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00857,"PCHG2":-0.28909,"CHG":0.18707,"PCHG":6.75988,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-08 08:01:26","ADY":820,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-312","SUBJID":"id-312","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.48925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-04","TRTSDTM":"2020-02-07 03:04:22","TRT01SDTM":"2020-02-07 03:04:22","AP01SDTM":"2020-02-07 03:04:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1275,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.52016,"AVALU":"U/L","BASE2":7.52016,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-12 03:04:22","ADY":34,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-312","SUBJID":"id-312","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.48925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-04","TRTSDTM":"2020-02-07 03:04:22","TRT01SDTM":"2020-02-07 03:04:22","AP01SDTM":"2020-02-07 03:04:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3540,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.11853,"AVALU":"U/L","BASE2":7.52016,"BASE":19.11853,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":11.59837,"PCHG2":154.23051,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-27 03:04:22","ADY":49,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-312","SUBJID":"id-312","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.48925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-04","TRTSDTM":"2020-02-07 03:04:22","TRT01SDTM":"2020-02-07 03:04:22","AP01SDTM":"2020-02-07 03:04:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1980,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.64416,"AVALU":"U/L","BASE2":7.52016,"BASE":19.11853,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.87599,"PCHG2":-38.24377,"CHG":-14.47437,"PCHG":-75.70857,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-05-16 03:04:22","ADY":99,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-312","SUBJID":"id-312","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.48925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-04","TRTSDTM":"2020-02-07 03:04:22","TRT01SDTM":"2020-02-07 03:04:22","AP01SDTM":"2020-02-07 03:04:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5898,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.58481,"AVALU":"U/L","BASE2":7.52016,"BASE":19.11853,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.06465,"PCHG2":160.43091,"CHG":0.46628,"PCHG":2.43889,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-01 03:04:22","ADY":145,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-312","SUBJID":"id-312","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.48925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-04","TRTSDTM":"2020-02-07 03:04:22","TRT01SDTM":"2020-02-07 03:04:22","AP01SDTM":"2020-02-07 03:04:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3222,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.62547,"AVALU":"U/L","BASE2":7.52016,"BASE":19.11853,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.10531,"PCHG2":160.9716,"CHG":0.50694,"PCHG":2.65157,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-01 03:04:22","ADY":268,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-312","SUBJID":"id-312","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.48925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-04","TRTSDTM":"2020-02-07 03:04:22","TRT01SDTM":"2020-02-07 03:04:22","AP01SDTM":"2020-02-07 03:04:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8040,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.59727,"AVALU":"U/L","BASE2":7.52016,"BASE":19.11853,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.07711,"PCHG2":147.29899,"CHG":-0.52126,"PCHG":-2.72647,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-07 03:04:22","ADY":578,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-312","SUBJID":"id-312","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.48925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-04","TRTSDTM":"2020-02-07 03:04:22","TRT01SDTM":"2020-02-07 03:04:22","AP01SDTM":"2020-02-07 03:04:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7445,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.15221,"AVALU":"U/L","BASE2":7.52016,"BASE":19.11853,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":22.63205,"PCHG2":300.95186,"CHG":11.03367,"PCHG":57.71194,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-27 03:04:22","ADY":720,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-312","SUBJID":"id-312","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.48925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-04","TRTSDTM":"2020-02-07 03:04:22","TRT01SDTM":"2020-02-07 03:04:22","AP01SDTM":"2020-02-07 03:04:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":775,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.01221,"AVALU":"mg/L","BASE2":8.01221,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-12 03:04:22","ADY":34,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-312","SUBJID":"id-312","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.48925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-04","TRTSDTM":"2020-02-07 03:04:22","TRT01SDTM":"2020-02-07 03:04:22","AP01SDTM":"2020-02-07 03:04:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6122,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.27685,"AVALU":"mg/L","BASE2":8.01221,"BASE":8.27685,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.26464,"PCHG2":3.303,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-27 03:04:22","ADY":49,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-312","SUBJID":"id-312","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.48925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-04","TRTSDTM":"2020-02-07 03:04:22","TRT01SDTM":"2020-02-07 03:04:22","AP01SDTM":"2020-02-07 03:04:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3283,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.67928,"AVALU":"mg/L","BASE2":8.01221,"BASE":8.27685,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.66707,"PCHG2":8.32564,"CHG":0.40242,"PCHG":4.86205,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-16 03:04:22","ADY":99,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-312","SUBJID":"id-312","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.48925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-04","TRTSDTM":"2020-02-07 03:04:22","TRT01SDTM":"2020-02-07 03:04:22","AP01SDTM":"2020-02-07 03:04:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3096,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.55783,"AVALU":"mg/L","BASE2":8.01221,"BASE":8.27685,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.54562,"PCHG2":19.29083,"CHG":1.28098,"PCHG":15.47664,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-01 03:04:22","ADY":145,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-312","SUBJID":"id-312","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.48925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-04","TRTSDTM":"2020-02-07 03:04:22","TRT01SDTM":"2020-02-07 03:04:22","AP01SDTM":"2020-02-07 03:04:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3866,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.32086,"AVALU":"mg/L","BASE2":8.01221,"BASE":8.27685,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.30865,"PCHG2":16.33317,"CHG":1.044,"PCHG":12.61354,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-01 03:04:22","ADY":268,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-312","SUBJID":"id-312","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.48925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-04","TRTSDTM":"2020-02-07 03:04:22","TRT01SDTM":"2020-02-07 03:04:22","AP01SDTM":"2020-02-07 03:04:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6061,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.72355,"AVALU":"mg/L","BASE2":8.01221,"BASE":8.27685,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.71135,"PCHG2":8.87827,"CHG":0.4467,"PCHG":5.397,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-07 03:04:22","ADY":578,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-312","SUBJID":"id-312","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.48925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-04","TRTSDTM":"2020-02-07 03:04:22","TRT01SDTM":"2020-02-07 03:04:22","AP01SDTM":"2020-02-07 03:04:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1184,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.93025,"AVALU":"mg/L","BASE2":8.01221,"BASE":8.27685,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.91804,"PCHG2":11.45799,"CHG":0.65339,"PCHG":7.89424,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-27 03:04:22","ADY":720,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-312","SUBJID":"id-312","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.48925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-04","TRTSDTM":"2020-02-07 03:04:22","TRT01SDTM":"2020-02-07 03:04:22","AP01SDTM":"2020-02-07 03:04:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6315,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97548,"AVALU":"g/L","BASE2":2.97548,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-12 03:04:22","ADY":34,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-312","SUBJID":"id-312","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.48925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-04","TRTSDTM":"2020-02-07 03:04:22","TRT01SDTM":"2020-02-07 03:04:22","AP01SDTM":"2020-02-07 03:04:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4203,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84823,"AVALU":"g/L","BASE2":2.97548,"BASE":2.84823,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.12725,"PCHG2":-4.27669,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-27 03:04:22","ADY":49,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-312","SUBJID":"id-312","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.48925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-04","TRTSDTM":"2020-02-07 03:04:22","TRT01SDTM":"2020-02-07 03:04:22","AP01SDTM":"2020-02-07 03:04:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":292,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96742,"AVALU":"g/L","BASE2":2.97548,"BASE":2.84823,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00806,"PCHG2":-0.27081,"CHG":0.11919,"PCHG":4.18486,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-16 03:04:22","ADY":99,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-312","SUBJID":"id-312","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.48925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-04","TRTSDTM":"2020-02-07 03:04:22","TRT01SDTM":"2020-02-07 03:04:22","AP01SDTM":"2020-02-07 03:04:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4319,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.69543,"AVALU":"g/L","BASE2":2.97548,"BASE":2.84823,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.28005,"PCHG2":-9.41205,"CHG":-0.1528,"PCHG":-5.3648,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-01 03:04:22","ADY":145,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-312","SUBJID":"id-312","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.48925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-04","TRTSDTM":"2020-02-07 03:04:22","TRT01SDTM":"2020-02-07 03:04:22","AP01SDTM":"2020-02-07 03:04:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7635,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83958,"AVALU":"g/L","BASE2":2.97548,"BASE":2.84823,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1359,"PCHG2":-4.56732,"CHG":-0.00865,"PCHG":-0.30361,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-01 03:04:22","ADY":268,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-312","SUBJID":"id-312","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.48925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-04","TRTSDTM":"2020-02-07 03:04:22","TRT01SDTM":"2020-02-07 03:04:22","AP01SDTM":"2020-02-07 03:04:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7776,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7464,"AVALU":"g/L","BASE2":2.97548,"BASE":2.84823,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.22908,"PCHG2":-7.69896,"CHG":-0.10183,"PCHG":-3.57516,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-07 03:04:22","ADY":578,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-312","SUBJID":"id-312","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.48925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-04","TRTSDTM":"2020-02-07 03:04:22","TRT01SDTM":"2020-02-07 03:04:22","AP01SDTM":"2020-02-07 03:04:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4210,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.09513,"AVALU":"g/L","BASE2":2.97548,"BASE":2.84823,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11965,"PCHG2":4.02113,"CHG":0.2469,"PCHG":8.66854,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-01-27 03:04:22","ADY":720,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-315","SUBJID":"id-315","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.43787,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-21","TRTSDTM":"2019-08-21 07:30:38","TRTEDTM":"2022-02-17 03:44:20","TRT01SDTM":"2019-08-21 07:30:38","TRT01EDTM":"2021-02-16 21:44:20","TRT02SDTM":"2021-02-16 21:44:20","TRT02EDTM":"2022-02-17 03:44:20","AP01SDTM":"2019-08-21 07:30:38","AP01EDTM":"2021-02-16 21:44:20","AP02SDTM":"2021-02-16 21:44:20","AP02EDTM":"2022-02-17 03:44:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":911,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-07","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5914,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.631,"AVALU":"U/L","BASE2":28.631,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-01 07:30:38","ADY":11,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-315","SUBJID":"id-315","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.43787,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-21","TRTSDTM":"2019-08-21 07:30:38","TRTEDTM":"2022-02-17 03:44:20","TRT01SDTM":"2019-08-21 07:30:38","TRT01EDTM":"2021-02-16 21:44:20","TRT02SDTM":"2021-02-16 21:44:20","TRT02EDTM":"2022-02-17 03:44:20","AP01SDTM":"2019-08-21 07:30:38","AP01EDTM":"2021-02-16 21:44:20","AP02SDTM":"2021-02-16 21:44:20","AP02EDTM":"2022-02-17 03:44:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":911,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-07","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5908,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.81994,"AVALU":"U/L","BASE2":28.631,"BASE":19.81994,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-8.81105,"PCHG2":-30.77452,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-15 07:30:38","ADY":147,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-315","SUBJID":"id-315","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.43787,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-21","TRTSDTM":"2019-08-21 07:30:38","TRTEDTM":"2022-02-17 03:44:20","TRT01SDTM":"2019-08-21 07:30:38","TRT01EDTM":"2021-02-16 21:44:20","TRT02SDTM":"2021-02-16 21:44:20","TRT02EDTM":"2022-02-17 03:44:20","AP01SDTM":"2019-08-21 07:30:38","AP01EDTM":"2021-02-16 21:44:20","AP02SDTM":"2021-02-16 21:44:20","AP02EDTM":"2022-02-17 03:44:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":911,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-07","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3065,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.14969,"AVALU":"U/L","BASE2":28.631,"BASE":19.81994,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.48131,"PCHG2":-1.68108,"CHG":8.32974,"PCHG":42.02707,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-15 07:30:38","ADY":268,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-315","SUBJID":"id-315","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.43787,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-21","TRTSDTM":"2019-08-21 07:30:38","TRTEDTM":"2022-02-17 03:44:20","TRT01SDTM":"2019-08-21 07:30:38","TRT01EDTM":"2021-02-16 21:44:20","TRT02SDTM":"2021-02-16 21:44:20","TRT02EDTM":"2022-02-17 03:44:20","AP01SDTM":"2019-08-21 07:30:38","AP01EDTM":"2021-02-16 21:44:20","AP02SDTM":"2021-02-16 21:44:20","AP02EDTM":"2022-02-17 03:44:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":911,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-07","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6720,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.56124,"AVALU":"U/L","BASE2":28.631,"BASE":19.81994,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-24.06976,"PCHG2":-84.06888,"CHG":-15.25871,"PCHG":-76.98662,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-06-05 07:30:38","ADY":289,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-315","SUBJID":"id-315","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.43787,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-21","TRTSDTM":"2019-08-21 07:30:38","TRTEDTM":"2022-02-17 03:44:20","TRT01SDTM":"2019-08-21 07:30:38","TRT01EDTM":"2021-02-16 21:44:20","TRT02SDTM":"2021-02-16 21:44:20","TRT02EDTM":"2022-02-17 03:44:20","AP01SDTM":"2019-08-21 07:30:38","AP01EDTM":"2021-02-16 21:44:20","AP02SDTM":"2021-02-16 21:44:20","AP02EDTM":"2022-02-17 03:44:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":911,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-07","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5787,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.22161,"AVALU":"U/L","BASE2":28.631,"BASE":19.81994,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-23.40939,"PCHG2":-81.76239,"CHG":-14.59834,"PCHG":-73.65478,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-04-11 07:30:38","ADY":599,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-315","SUBJID":"id-315","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.43787,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-21","TRTSDTM":"2019-08-21 07:30:38","TRTEDTM":"2022-02-17 03:44:20","TRT01SDTM":"2019-08-21 07:30:38","TRT01EDTM":"2021-02-16 21:44:20","TRT02SDTM":"2021-02-16 21:44:20","TRT02EDTM":"2022-02-17 03:44:20","AP01SDTM":"2019-08-21 07:30:38","AP01EDTM":"2021-02-16 21:44:20","AP02SDTM":"2021-02-16 21:44:20","AP02EDTM":"2022-02-17 03:44:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":911,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-07","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5830,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.9047,"AVALU":"U/L","BASE2":28.631,"BASE":19.81994,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.7263,"PCHG2":-9.52218,"CHG":6.08476,"PCHG":30.70017,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-22 07:30:38","ADY":732,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-315","SUBJID":"id-315","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.43787,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-21","TRTSDTM":"2019-08-21 07:30:38","TRTEDTM":"2022-02-17 03:44:20","TRT01SDTM":"2019-08-21 07:30:38","TRT01EDTM":"2021-02-16 21:44:20","TRT02SDTM":"2021-02-16 21:44:20","TRT02EDTM":"2022-02-17 03:44:20","AP01SDTM":"2019-08-21 07:30:38","AP01EDTM":"2021-02-16 21:44:20","AP02SDTM":"2021-02-16 21:44:20","AP02EDTM":"2022-02-17 03:44:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":911,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-07","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6301,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.65152,"AVALU":"U/L","BASE2":28.631,"BASE":19.81994,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-19.97948,"PCHG2":-69.78268,"CHG":-11.16842,"PCHG":-56.34942,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-13 07:30:38","ADY":876,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-315","SUBJID":"id-315","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.43787,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-21","TRTSDTM":"2019-08-21 07:30:38","TRTEDTM":"2022-02-17 03:44:20","TRT01SDTM":"2019-08-21 07:30:38","TRT01EDTM":"2021-02-16 21:44:20","TRT02SDTM":"2021-02-16 21:44:20","TRT02EDTM":"2022-02-17 03:44:20","AP01SDTM":"2019-08-21 07:30:38","AP01EDTM":"2021-02-16 21:44:20","AP02SDTM":"2021-02-16 21:44:20","AP02EDTM":"2022-02-17 03:44:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":911,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-07","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4140,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.91491,"AVALU":"mg/L","BASE2":7.91491,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"-2","BTOXGR":"3","ADTM":"2019-09-01 07:30:38","ADY":11,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-315","SUBJID":"id-315","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.43787,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-21","TRTSDTM":"2019-08-21 07:30:38","TRTEDTM":"2022-02-17 03:44:20","TRT01SDTM":"2019-08-21 07:30:38","TRT01EDTM":"2021-02-16 21:44:20","TRT02SDTM":"2021-02-16 21:44:20","TRT02EDTM":"2022-02-17 03:44:20","AP01SDTM":"2019-08-21 07:30:38","AP01EDTM":"2021-02-16 21:44:20","AP02SDTM":"2021-02-16 21:44:20","AP02EDTM":"2022-02-17 03:44:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":911,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-07","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1035,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.26714,"AVALU":"mg/L","BASE2":7.91491,"BASE":10.26714,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.35223,"PCHG2":29.71893,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2020-01-15 07:30:38","ADY":147,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-315","SUBJID":"id-315","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.43787,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-21","TRTSDTM":"2019-08-21 07:30:38","TRTEDTM":"2022-02-17 03:44:20","TRT01SDTM":"2019-08-21 07:30:38","TRT01EDTM":"2021-02-16 21:44:20","TRT02SDTM":"2021-02-16 21:44:20","TRT02EDTM":"2022-02-17 03:44:20","AP01SDTM":"2019-08-21 07:30:38","AP01EDTM":"2021-02-16 21:44:20","AP02SDTM":"2021-02-16 21:44:20","AP02EDTM":"2022-02-17 03:44:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":911,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-07","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2491,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.54024,"AVALU":"mg/L","BASE2":7.91491,"BASE":10.26714,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.62533,"PCHG2":7.90061,"CHG":-1.7269,"PCHG":-16.81969,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-05-15 07:30:38","ADY":268,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-315","SUBJID":"id-315","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.43787,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-21","TRTSDTM":"2019-08-21 07:30:38","TRTEDTM":"2022-02-17 03:44:20","TRT01SDTM":"2019-08-21 07:30:38","TRT01EDTM":"2021-02-16 21:44:20","TRT02SDTM":"2021-02-16 21:44:20","TRT02EDTM":"2022-02-17 03:44:20","AP01SDTM":"2019-08-21 07:30:38","AP01EDTM":"2021-02-16 21:44:20","AP02SDTM":"2021-02-16 21:44:20","AP02EDTM":"2022-02-17 03:44:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":911,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-07","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6577,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.32381,"AVALU":"mg/L","BASE2":7.91491,"BASE":10.26714,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.4089,"PCHG2":5.16619,"CHG":-1.94333,"PCHG":-18.92765,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-06-05 07:30:38","ADY":289,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-315","SUBJID":"id-315","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.43787,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-21","TRTSDTM":"2019-08-21 07:30:38","TRTEDTM":"2022-02-17 03:44:20","TRT01SDTM":"2019-08-21 07:30:38","TRT01EDTM":"2021-02-16 21:44:20","TRT02SDTM":"2021-02-16 21:44:20","TRT02EDTM":"2022-02-17 03:44:20","AP01SDTM":"2019-08-21 07:30:38","AP01EDTM":"2021-02-16 21:44:20","AP02SDTM":"2021-02-16 21:44:20","AP02EDTM":"2022-02-17 03:44:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":911,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-07","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3877,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.64207,"AVALU":"mg/L","BASE2":7.91491,"BASE":10.26714,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.72716,"PCHG2":34.45601,"CHG":0.37494,"PCHG":3.6518,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"3","BTOXGR":"3","ADTM":"2021-04-11 07:30:38","ADY":599,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-315","SUBJID":"id-315","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.43787,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-21","TRTSDTM":"2019-08-21 07:30:38","TRTEDTM":"2022-02-17 03:44:20","TRT01SDTM":"2019-08-21 07:30:38","TRT01EDTM":"2021-02-16 21:44:20","TRT02SDTM":"2021-02-16 21:44:20","TRT02EDTM":"2022-02-17 03:44:20","AP01SDTM":"2019-08-21 07:30:38","AP01EDTM":"2021-02-16 21:44:20","AP02SDTM":"2021-02-16 21:44:20","AP02EDTM":"2022-02-17 03:44:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":911,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-07","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8026,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.13426,"AVALU":"mg/L","BASE2":7.91491,"BASE":10.26714,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.21935,"PCHG2":2.77129,"CHG":-2.13288,"PCHG":-20.77387,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-08-22 07:30:38","ADY":732,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-315","SUBJID":"id-315","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.43787,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-21","TRTSDTM":"2019-08-21 07:30:38","TRTEDTM":"2022-02-17 03:44:20","TRT01SDTM":"2019-08-21 07:30:38","TRT01EDTM":"2021-02-16 21:44:20","TRT02SDTM":"2021-02-16 21:44:20","TRT02EDTM":"2022-02-17 03:44:20","AP01SDTM":"2019-08-21 07:30:38","AP01EDTM":"2021-02-16 21:44:20","AP02SDTM":"2021-02-16 21:44:20","AP02EDTM":"2022-02-17 03:44:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":911,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-07","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3937,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.21584,"AVALU":"mg/L","BASE2":7.91491,"BASE":10.26714,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.30093,"PCHG2":29.07085,"CHG":-0.05129,"PCHG":-0.4996,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"1","BTOXGR":"3","ADTM":"2022-01-13 07:30:38","ADY":876,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-315","SUBJID":"id-315","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.43787,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-21","TRTSDTM":"2019-08-21 07:30:38","TRTEDTM":"2022-02-17 03:44:20","TRT01SDTM":"2019-08-21 07:30:38","TRT01EDTM":"2021-02-16 21:44:20","TRT02SDTM":"2021-02-16 21:44:20","TRT02EDTM":"2022-02-17 03:44:20","AP01SDTM":"2019-08-21 07:30:38","AP01EDTM":"2021-02-16 21:44:20","AP02SDTM":"2021-02-16 21:44:20","AP02EDTM":"2022-02-17 03:44:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":911,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-07","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6228,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82709,"AVALU":"g/L","BASE2":2.82709,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-01 07:30:38","ADY":11,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-315","SUBJID":"id-315","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.43787,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-21","TRTSDTM":"2019-08-21 07:30:38","TRTEDTM":"2022-02-17 03:44:20","TRT01SDTM":"2019-08-21 07:30:38","TRT01EDTM":"2021-02-16 21:44:20","TRT02SDTM":"2021-02-16 21:44:20","TRT02EDTM":"2022-02-17 03:44:20","AP01SDTM":"2019-08-21 07:30:38","AP01EDTM":"2021-02-16 21:44:20","AP02SDTM":"2021-02-16 21:44:20","AP02EDTM":"2022-02-17 03:44:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":911,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-07","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7719,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93515,"AVALU":"g/L","BASE2":2.82709,"BASE":2.93515,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.10806,"PCHG2":3.82215,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-15 07:30:38","ADY":147,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-315","SUBJID":"id-315","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.43787,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-21","TRTSDTM":"2019-08-21 07:30:38","TRTEDTM":"2022-02-17 03:44:20","TRT01SDTM":"2019-08-21 07:30:38","TRT01EDTM":"2021-02-16 21:44:20","TRT02SDTM":"2021-02-16 21:44:20","TRT02EDTM":"2022-02-17 03:44:20","AP01SDTM":"2019-08-21 07:30:38","AP01EDTM":"2021-02-16 21:44:20","AP02SDTM":"2021-02-16 21:44:20","AP02EDTM":"2022-02-17 03:44:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":911,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-07","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3544,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88566,"AVALU":"g/L","BASE2":2.82709,"BASE":2.93515,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05857,"PCHG2":2.07158,"CHG":-0.04949,"PCHG":-1.68613,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-15 07:30:38","ADY":268,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-315","SUBJID":"id-315","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.43787,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-21","TRTSDTM":"2019-08-21 07:30:38","TRTEDTM":"2022-02-17 03:44:20","TRT01SDTM":"2019-08-21 07:30:38","TRT01EDTM":"2021-02-16 21:44:20","TRT02SDTM":"2021-02-16 21:44:20","TRT02EDTM":"2022-02-17 03:44:20","AP01SDTM":"2019-08-21 07:30:38","AP01EDTM":"2021-02-16 21:44:20","AP02SDTM":"2021-02-16 21:44:20","AP02EDTM":"2022-02-17 03:44:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":911,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-07","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8338,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93157,"AVALU":"g/L","BASE2":2.82709,"BASE":2.93515,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10448,"PCHG2":3.69557,"CHG":-0.00358,"PCHG":-0.12192,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-05 07:30:38","ADY":289,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-315","SUBJID":"id-315","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.43787,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-21","TRTSDTM":"2019-08-21 07:30:38","TRTEDTM":"2022-02-17 03:44:20","TRT01SDTM":"2019-08-21 07:30:38","TRT01EDTM":"2021-02-16 21:44:20","TRT02SDTM":"2021-02-16 21:44:20","TRT02EDTM":"2022-02-17 03:44:20","AP01SDTM":"2019-08-21 07:30:38","AP01EDTM":"2021-02-16 21:44:20","AP02SDTM":"2021-02-16 21:44:20","AP02EDTM":"2022-02-17 03:44:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":911,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-07","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5963,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.15105,"AVALU":"g/L","BASE2":2.82709,"BASE":2.93515,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.32396,"PCHG2":11.45918,"CHG":0.21591,"PCHG":7.35587,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-04-11 07:30:38","ADY":599,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-315","SUBJID":"id-315","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.43787,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-21","TRTSDTM":"2019-08-21 07:30:38","TRTEDTM":"2022-02-17 03:44:20","TRT01SDTM":"2019-08-21 07:30:38","TRT01EDTM":"2021-02-16 21:44:20","TRT02SDTM":"2021-02-16 21:44:20","TRT02EDTM":"2022-02-17 03:44:20","AP01SDTM":"2019-08-21 07:30:38","AP01EDTM":"2021-02-16 21:44:20","AP02SDTM":"2021-02-16 21:44:20","AP02EDTM":"2022-02-17 03:44:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":911,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-07","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7737,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05852,"AVALU":"g/L","BASE2":2.82709,"BASE":2.93515,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.23143,"PCHG2":8.18611,"CHG":0.12337,"PCHG":4.2033,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-08-22 07:30:38","ADY":732,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-315","SUBJID":"id-315","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.43787,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-21","TRTSDTM":"2019-08-21 07:30:38","TRTEDTM":"2022-02-17 03:44:20","TRT01SDTM":"2019-08-21 07:30:38","TRT01EDTM":"2021-02-16 21:44:20","TRT02SDTM":"2021-02-16 21:44:20","TRT02EDTM":"2022-02-17 03:44:20","AP01SDTM":"2019-08-21 07:30:38","AP01EDTM":"2021-02-16 21:44:20","AP02SDTM":"2021-02-16 21:44:20","AP02EDTM":"2022-02-17 03:44:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":911,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-07","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4676,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86647,"AVALU":"g/L","BASE2":2.82709,"BASE":2.93515,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03938,"PCHG2":1.39284,"CHG":-0.06868,"PCHG":-2.33988,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-13 07:30:38","ADY":876,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-316","SUBJID":"id-316","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.57574,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-12","TRTSDTM":"2020-09-15 10:05:42","TRTEDTM":"2023-09-16 04:05:42","TRT01SDTM":"2020-09-15 10:05:42","TRT01EDTM":"2022-09-15 22:05:42","TRT02SDTM":"2022-09-15 22:05:42","TRT02EDTM":"2023-09-16 04:05:42","AP01SDTM":"2020-09-15 10:05:42","AP01EDTM":"2022-09-15 22:05:42","AP02SDTM":"2022-09-15 22:05:42","AP02EDTM":"2023-09-16 04:05:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-12","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7474,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.69161,"AVALU":"U/L","BASE2":28.69161,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-02 10:05:42","ADY":78,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-316","SUBJID":"id-316","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.57574,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-12","TRTSDTM":"2020-09-15 10:05:42","TRTEDTM":"2023-09-16 04:05:42","TRT01SDTM":"2020-09-15 10:05:42","TRT01EDTM":"2022-09-15 22:05:42","TRT02SDTM":"2022-09-15 22:05:42","TRT02EDTM":"2023-09-16 04:05:42","AP01SDTM":"2020-09-15 10:05:42","AP01EDTM":"2022-09-15 22:05:42","AP02SDTM":"2022-09-15 22:05:42","AP02EDTM":"2023-09-16 04:05:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-12","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5858,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.64799,"AVALU":"U/L","BASE2":28.69161,"BASE":15.64799,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-13.04362,"PCHG2":-45.46145,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-16 10:05:42","ADY":154,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-316","SUBJID":"id-316","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.57574,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-12","TRTSDTM":"2020-09-15 10:05:42","TRTEDTM":"2023-09-16 04:05:42","TRT01SDTM":"2020-09-15 10:05:42","TRT01EDTM":"2022-09-15 22:05:42","TRT02SDTM":"2022-09-15 22:05:42","TRT02EDTM":"2023-09-16 04:05:42","AP01SDTM":"2020-09-15 10:05:42","AP01EDTM":"2022-09-15 22:05:42","AP02SDTM":"2022-09-15 22:05:42","AP02EDTM":"2023-09-16 04:05:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-12","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":907,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.16413,"AVALU":"U/L","BASE2":28.69161,"BASE":15.64799,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.52749,"PCHG2":-33.20653,"CHG":3.51613,"PCHG":22.4702,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-17 10:05:42","ADY":244,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-316","SUBJID":"id-316","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.57574,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-12","TRTSDTM":"2020-09-15 10:05:42","TRTEDTM":"2023-09-16 04:05:42","TRT01SDTM":"2020-09-15 10:05:42","TRT01EDTM":"2022-09-15 22:05:42","TRT02SDTM":"2022-09-15 22:05:42","TRT02EDTM":"2023-09-16 04:05:42","AP01SDTM":"2020-09-15 10:05:42","AP01EDTM":"2022-09-15 22:05:42","AP02SDTM":"2022-09-15 22:05:42","AP02EDTM":"2023-09-16 04:05:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-12","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6027,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.51008,"AVALU":"U/L","BASE2":28.69161,"BASE":15.64799,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.18153,"PCHG2":-59.88346,"CHG":-4.13791,"PCHG":-26.44371,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-28 10:05:42","ADY":378,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-316","SUBJID":"id-316","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.57574,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-12","TRTSDTM":"2020-09-15 10:05:42","TRTEDTM":"2023-09-16 04:05:42","TRT01SDTM":"2020-09-15 10:05:42","TRT01EDTM":"2022-09-15 22:05:42","TRT02SDTM":"2022-09-15 22:05:42","TRT02EDTM":"2023-09-16 04:05:42","AP01SDTM":"2020-09-15 10:05:42","AP01EDTM":"2022-09-15 22:05:42","AP02SDTM":"2022-09-15 22:05:42","AP02EDTM":"2023-09-16 04:05:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-12","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5565,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.7778,"AVALU":"U/L","BASE2":28.69161,"BASE":15.64799,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.91381,"PCHG2":-27.58232,"CHG":5.12981,"PCHG":32.78255,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-22 10:05:42","ADY":494,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-316","SUBJID":"id-316","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.57574,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-12","TRTSDTM":"2020-09-15 10:05:42","TRTEDTM":"2023-09-16 04:05:42","TRT01SDTM":"2020-09-15 10:05:42","TRT01EDTM":"2022-09-15 22:05:42","TRT02SDTM":"2022-09-15 22:05:42","TRT02EDTM":"2023-09-16 04:05:42","AP01SDTM":"2020-09-15 10:05:42","AP01EDTM":"2022-09-15 22:05:42","AP02SDTM":"2022-09-15 22:05:42","AP02EDTM":"2023-09-16 04:05:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-12","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7522,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.24956,"AVALU":"U/L","BASE2":28.69161,"BASE":15.64799,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.55795,"PCHG2":5.42997,"CHG":14.60157,"PCHG":93.31274,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-18 10:05:42","ADY":610,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-316","SUBJID":"id-316","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.57574,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-12","TRTSDTM":"2020-09-15 10:05:42","TRTEDTM":"2023-09-16 04:05:42","TRT01SDTM":"2020-09-15 10:05:42","TRT01EDTM":"2022-09-15 22:05:42","TRT02SDTM":"2022-09-15 22:05:42","TRT02EDTM":"2023-09-16 04:05:42","AP01SDTM":"2020-09-15 10:05:42","AP01EDTM":"2022-09-15 22:05:42","AP02SDTM":"2022-09-15 22:05:42","AP02EDTM":"2023-09-16 04:05:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-12","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":619,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.5821,"AVALU":"U/L","BASE2":28.69161,"BASE":15.64799,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-25.10952,"PCHG2":-87.51517,"CHG":-12.06589,"PCHG":-77.10825,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2023-05-14 10:05:42","ADY":971,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-316","SUBJID":"id-316","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.57574,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-12","TRTSDTM":"2020-09-15 10:05:42","TRTEDTM":"2023-09-16 04:05:42","TRT01SDTM":"2020-09-15 10:05:42","TRT01EDTM":"2022-09-15 22:05:42","TRT02SDTM":"2022-09-15 22:05:42","TRT02EDTM":"2023-09-16 04:05:42","AP01SDTM":"2020-09-15 10:05:42","AP01EDTM":"2022-09-15 22:05:42","AP02SDTM":"2022-09-15 22:05:42","AP02EDTM":"2023-09-16 04:05:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-12","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7337,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.68363,"AVALU":"mg/L","BASE2":7.68363,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-12-02 10:05:42","ADY":78,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-316","SUBJID":"id-316","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.57574,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-12","TRTSDTM":"2020-09-15 10:05:42","TRTEDTM":"2023-09-16 04:05:42","TRT01SDTM":"2020-09-15 10:05:42","TRT01EDTM":"2022-09-15 22:05:42","TRT02SDTM":"2022-09-15 22:05:42","TRT02EDTM":"2023-09-16 04:05:42","AP01SDTM":"2020-09-15 10:05:42","AP01EDTM":"2022-09-15 22:05:42","AP02SDTM":"2022-09-15 22:05:42","AP02EDTM":"2023-09-16 04:05:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-12","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1522,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.54154,"AVALU":"mg/L","BASE2":7.68363,"BASE":9.54154,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.85791,"PCHG2":24.18008,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-16 10:05:42","ADY":154,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-316","SUBJID":"id-316","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.57574,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-12","TRTSDTM":"2020-09-15 10:05:42","TRTEDTM":"2023-09-16 04:05:42","TRT01SDTM":"2020-09-15 10:05:42","TRT01EDTM":"2022-09-15 22:05:42","TRT02SDTM":"2022-09-15 22:05:42","TRT02EDTM":"2023-09-16 04:05:42","AP01SDTM":"2020-09-15 10:05:42","AP01EDTM":"2022-09-15 22:05:42","AP02SDTM":"2022-09-15 22:05:42","AP02EDTM":"2023-09-16 04:05:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-12","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4717,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.78686,"AVALU":"mg/L","BASE2":7.68363,"BASE":9.54154,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.10323,"PCHG2":14.35813,"CHG":-0.75468,"PCHG":-7.90944,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-17 10:05:42","ADY":244,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-316","SUBJID":"id-316","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.57574,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-12","TRTSDTM":"2020-09-15 10:05:42","TRTEDTM":"2023-09-16 04:05:42","TRT01SDTM":"2020-09-15 10:05:42","TRT01EDTM":"2022-09-15 22:05:42","TRT02SDTM":"2022-09-15 22:05:42","TRT02EDTM":"2023-09-16 04:05:42","AP01SDTM":"2020-09-15 10:05:42","AP01EDTM":"2022-09-15 22:05:42","AP02SDTM":"2022-09-15 22:05:42","AP02EDTM":"2023-09-16 04:05:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-12","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7906,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.60296,"AVALU":"mg/L","BASE2":7.68363,"BASE":9.54154,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.91933,"PCHG2":37.99408,"CHG":1.06142,"PCHG":11.12417,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-09-28 10:05:42","ADY":378,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-316","SUBJID":"id-316","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.57574,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-12","TRTSDTM":"2020-09-15 10:05:42","TRTEDTM":"2023-09-16 04:05:42","TRT01SDTM":"2020-09-15 10:05:42","TRT01EDTM":"2022-09-15 22:05:42","TRT02SDTM":"2022-09-15 22:05:42","TRT02EDTM":"2023-09-16 04:05:42","AP01SDTM":"2020-09-15 10:05:42","AP01EDTM":"2022-09-15 22:05:42","AP02SDTM":"2022-09-15 22:05:42","AP02EDTM":"2023-09-16 04:05:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-12","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5499,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.71466,"AVALU":"mg/L","BASE2":7.68363,"BASE":9.54154,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.03103,"PCHG2":13.41853,"CHG":-0.82688,"PCHG":-8.66608,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-22 10:05:42","ADY":494,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-316","SUBJID":"id-316","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.57574,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-12","TRTSDTM":"2020-09-15 10:05:42","TRTEDTM":"2023-09-16 04:05:42","TRT01SDTM":"2020-09-15 10:05:42","TRT01EDTM":"2022-09-15 22:05:42","TRT02SDTM":"2022-09-15 22:05:42","TRT02EDTM":"2023-09-16 04:05:42","AP01SDTM":"2020-09-15 10:05:42","AP01EDTM":"2022-09-15 22:05:42","AP02SDTM":"2022-09-15 22:05:42","AP02EDTM":"2023-09-16 04:05:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-12","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3936,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.5521,"AVALU":"mg/L","BASE2":7.68363,"BASE":9.54154,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.86847,"PCHG2":11.30282,"CHG":-0.98944,"PCHG":-10.36983,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-18 10:05:42","ADY":610,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-316","SUBJID":"id-316","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.57574,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-12","TRTSDTM":"2020-09-15 10:05:42","TRTEDTM":"2023-09-16 04:05:42","TRT01SDTM":"2020-09-15 10:05:42","TRT01EDTM":"2022-09-15 22:05:42","TRT02SDTM":"2022-09-15 22:05:42","TRT02EDTM":"2023-09-16 04:05:42","AP01SDTM":"2020-09-15 10:05:42","AP01EDTM":"2022-09-15 22:05:42","AP02SDTM":"2022-09-15 22:05:42","AP02EDTM":"2023-09-16 04:05:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-12","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1333,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.35909,"AVALU":"mg/L","BASE2":7.68363,"BASE":9.54154,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.67546,"PCHG2":21.80556,"CHG":-0.18245,"PCHG":-1.91215,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-14 10:05:42","ADY":971,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-316","SUBJID":"id-316","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.57574,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-12","TRTSDTM":"2020-09-15 10:05:42","TRTEDTM":"2023-09-16 04:05:42","TRT01SDTM":"2020-09-15 10:05:42","TRT01EDTM":"2022-09-15 22:05:42","TRT02SDTM":"2022-09-15 22:05:42","TRT02EDTM":"2023-09-16 04:05:42","AP01SDTM":"2020-09-15 10:05:42","AP01EDTM":"2022-09-15 22:05:42","AP02SDTM":"2022-09-15 22:05:42","AP02EDTM":"2023-09-16 04:05:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-12","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4015,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80224,"AVALU":"g/L","BASE2":2.80224,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-02 10:05:42","ADY":78,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-316","SUBJID":"id-316","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.57574,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-12","TRTSDTM":"2020-09-15 10:05:42","TRTEDTM":"2023-09-16 04:05:42","TRT01SDTM":"2020-09-15 10:05:42","TRT01EDTM":"2022-09-15 22:05:42","TRT02SDTM":"2022-09-15 22:05:42","TRT02EDTM":"2023-09-16 04:05:42","AP01SDTM":"2020-09-15 10:05:42","AP01EDTM":"2022-09-15 22:05:42","AP02SDTM":"2022-09-15 22:05:42","AP02EDTM":"2023-09-16 04:05:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-12","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2206,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93755,"AVALU":"g/L","BASE2":2.80224,"BASE":2.93755,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.13531,"PCHG2":4.82869,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-16 10:05:42","ADY":154,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-316","SUBJID":"id-316","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.57574,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-12","TRTSDTM":"2020-09-15 10:05:42","TRTEDTM":"2023-09-16 04:05:42","TRT01SDTM":"2020-09-15 10:05:42","TRT01EDTM":"2022-09-15 22:05:42","TRT02SDTM":"2022-09-15 22:05:42","TRT02EDTM":"2023-09-16 04:05:42","AP01SDTM":"2020-09-15 10:05:42","AP01EDTM":"2022-09-15 22:05:42","AP02SDTM":"2022-09-15 22:05:42","AP02EDTM":"2023-09-16 04:05:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-12","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":391,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00898,"AVALU":"g/L","BASE2":2.80224,"BASE":2.93755,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.20674,"PCHG2":7.37776,"CHG":0.07143,"PCHG":2.43165,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-05-17 10:05:42","ADY":244,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-316","SUBJID":"id-316","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.57574,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-12","TRTSDTM":"2020-09-15 10:05:42","TRTEDTM":"2023-09-16 04:05:42","TRT01SDTM":"2020-09-15 10:05:42","TRT01EDTM":"2022-09-15 22:05:42","TRT02SDTM":"2022-09-15 22:05:42","TRT02EDTM":"2023-09-16 04:05:42","AP01SDTM":"2020-09-15 10:05:42","AP01EDTM":"2022-09-15 22:05:42","AP02SDTM":"2022-09-15 22:05:42","AP02EDTM":"2023-09-16 04:05:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-12","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5119,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99024,"AVALU":"g/L","BASE2":2.80224,"BASE":2.93755,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.188,"PCHG2":6.70879,"CHG":0.05268,"PCHG":1.7935,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-28 10:05:42","ADY":378,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-316","SUBJID":"id-316","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.57574,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-12","TRTSDTM":"2020-09-15 10:05:42","TRTEDTM":"2023-09-16 04:05:42","TRT01SDTM":"2020-09-15 10:05:42","TRT01EDTM":"2022-09-15 22:05:42","TRT02SDTM":"2022-09-15 22:05:42","TRT02EDTM":"2023-09-16 04:05:42","AP01SDTM":"2020-09-15 10:05:42","AP01EDTM":"2022-09-15 22:05:42","AP02SDTM":"2022-09-15 22:05:42","AP02EDTM":"2023-09-16 04:05:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-12","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1626,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8249,"AVALU":"g/L","BASE2":2.80224,"BASE":2.93755,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02266,"PCHG2":0.8088,"CHG":-0.11265,"PCHG":-3.83472,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-22 10:05:42","ADY":494,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-316","SUBJID":"id-316","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.57574,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-12","TRTSDTM":"2020-09-15 10:05:42","TRTEDTM":"2023-09-16 04:05:42","TRT01SDTM":"2020-09-15 10:05:42","TRT01EDTM":"2022-09-15 22:05:42","TRT02SDTM":"2022-09-15 22:05:42","TRT02EDTM":"2023-09-16 04:05:42","AP01SDTM":"2020-09-15 10:05:42","AP01EDTM":"2022-09-15 22:05:42","AP02SDTM":"2022-09-15 22:05:42","AP02EDTM":"2023-09-16 04:05:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-12","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8201,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7297,"AVALU":"g/L","BASE2":2.80224,"BASE":2.93755,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07254,"PCHG2":-2.58876,"CHG":-0.20785,"PCHG":-7.07578,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-18 10:05:42","ADY":610,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-316","SUBJID":"id-316","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.57574,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-12","TRTSDTM":"2020-09-15 10:05:42","TRTEDTM":"2023-09-16 04:05:42","TRT01SDTM":"2020-09-15 10:05:42","TRT01EDTM":"2022-09-15 22:05:42","TRT02SDTM":"2022-09-15 22:05:42","TRT02EDTM":"2023-09-16 04:05:42","AP01SDTM":"2020-09-15 10:05:42","AP01EDTM":"2022-09-15 22:05:42","AP02SDTM":"2022-09-15 22:05:42","AP02EDTM":"2023-09-16 04:05:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-12","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6578,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9299,"AVALU":"g/L","BASE2":2.80224,"BASE":2.93755,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12766,"PCHG2":4.55554,"CHG":-0.00765,"PCHG":-0.26057,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-14 10:05:42","ADY":971,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-329","SUBJID":"id-329","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.07281,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-03","TRTSDTM":"2019-07-06 20:54:49","TRTEDTM":"2022-02-13 21:01:33","TRT01SDTM":"2019-07-06 20:54:49","TRT01EDTM":"2021-02-13 15:01:33","TRT02SDTM":"2021-02-13 15:01:33","TRT02EDTM":"2022-02-13 21:01:33","AP01SDTM":"2019-07-06 20:54:49","AP01EDTM":"2021-02-13 15:01:33","AP02SDTM":"2021-02-13 15:01:33","AP02EDTM":"2022-02-13 21:01:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":954,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-06","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6873,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.6076,"AVALU":"U/L","BASE2":17.6076,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-11 20:54:49","ADY":36,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-329","SUBJID":"id-329","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.07281,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-03","TRTSDTM":"2019-07-06 20:54:49","TRTEDTM":"2022-02-13 21:01:33","TRT01SDTM":"2019-07-06 20:54:49","TRT01EDTM":"2021-02-13 15:01:33","TRT02SDTM":"2021-02-13 15:01:33","TRT02EDTM":"2022-02-13 21:01:33","AP01SDTM":"2019-07-06 20:54:49","AP01EDTM":"2021-02-13 15:01:33","AP02SDTM":"2021-02-13 15:01:33","AP02EDTM":"2022-02-13 21:01:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":954,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-06","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7587,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.73596,"AVALU":"U/L","BASE2":17.6076,"BASE":8.73596,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-8.87164,"PCHG2":-50.3853,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-26 20:54:49","ADY":173,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-329","SUBJID":"id-329","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.07281,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-03","TRTSDTM":"2019-07-06 20:54:49","TRTEDTM":"2022-02-13 21:01:33","TRT01SDTM":"2019-07-06 20:54:49","TRT01EDTM":"2021-02-13 15:01:33","TRT02SDTM":"2021-02-13 15:01:33","TRT02EDTM":"2022-02-13 21:01:33","AP01SDTM":"2019-07-06 20:54:49","AP01EDTM":"2021-02-13 15:01:33","AP02SDTM":"2021-02-13 15:01:33","AP02EDTM":"2022-02-13 21:01:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":954,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-06","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5563,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.90884,"AVALU":"U/L","BASE2":17.6076,"BASE":8.73596,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.30124,"PCHG2":18.74894,"CHG":12.17288,"PCHG":139.34226,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-07 20:54:49","ADY":306,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-329","SUBJID":"id-329","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.07281,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-03","TRTSDTM":"2019-07-06 20:54:49","TRTEDTM":"2022-02-13 21:01:33","TRT01SDTM":"2019-07-06 20:54:49","TRT01EDTM":"2021-02-13 15:01:33","TRT02SDTM":"2021-02-13 15:01:33","TRT02EDTM":"2022-02-13 21:01:33","AP01SDTM":"2019-07-06 20:54:49","AP01EDTM":"2021-02-13 15:01:33","AP02SDTM":"2021-02-13 15:01:33","AP02EDTM":"2022-02-13 21:01:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":954,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-06","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5681,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.80062,"AVALU":"U/L","BASE2":17.6076,"BASE":8.73596,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.19302,"PCHG2":63.56924,"CHG":20.06466,"PCHG":229.679,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-03 20:54:49","ADY":394,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-329","SUBJID":"id-329","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.07281,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-03","TRTSDTM":"2019-07-06 20:54:49","TRTEDTM":"2022-02-13 21:01:33","TRT01SDTM":"2019-07-06 20:54:49","TRT01EDTM":"2021-02-13 15:01:33","TRT02SDTM":"2021-02-13 15:01:33","TRT02EDTM":"2022-02-13 21:01:33","AP01SDTM":"2019-07-06 20:54:49","AP01EDTM":"2021-02-13 15:01:33","AP02SDTM":"2021-02-13 15:01:33","AP02EDTM":"2022-02-13 21:01:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":954,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-06","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6124,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.65407,"AVALU":"U/L","BASE2":17.6076,"BASE":8.73596,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.04647,"PCHG2":51.3782,"CHG":17.91811,"PCHG":205.10756,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-28 20:54:49","ADY":603,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-329","SUBJID":"id-329","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.07281,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-03","TRTSDTM":"2019-07-06 20:54:49","TRTEDTM":"2022-02-13 21:01:33","TRT01SDTM":"2019-07-06 20:54:49","TRT01EDTM":"2021-02-13 15:01:33","TRT02SDTM":"2021-02-13 15:01:33","TRT02EDTM":"2022-02-13 21:01:33","AP01SDTM":"2019-07-06 20:54:49","AP01EDTM":"2021-02-13 15:01:33","AP02SDTM":"2021-02-13 15:01:33","AP02EDTM":"2022-02-13 21:01:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":954,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-06","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4375,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.94996,"AVALU":"U/L","BASE2":17.6076,"BASE":8.73596,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.65764,"PCHG2":-15.0937,"CHG":6.214,"PCHG":71.13134,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-13 20:54:49","ADY":616,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-329","SUBJID":"id-329","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.07281,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-03","TRTSDTM":"2019-07-06 20:54:49","TRTEDTM":"2022-02-13 21:01:33","TRT01SDTM":"2019-07-06 20:54:49","TRT01EDTM":"2021-02-13 15:01:33","TRT02SDTM":"2021-02-13 15:01:33","TRT02EDTM":"2022-02-13 21:01:33","AP01SDTM":"2019-07-06 20:54:49","AP01EDTM":"2021-02-13 15:01:33","AP02SDTM":"2021-02-13 15:01:33","AP02EDTM":"2022-02-13 21:01:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":954,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-06","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":604,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.05429,"AVALU":"U/L","BASE2":17.6076,"BASE":8.73596,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.44669,"PCHG2":53.65118,"CHG":18.31833,"PCHG":209.68884,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-26 20:54:49","ADY":660,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-329","SUBJID":"id-329","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.07281,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-03","TRTSDTM":"2019-07-06 20:54:49","TRTEDTM":"2022-02-13 21:01:33","TRT01SDTM":"2019-07-06 20:54:49","TRT01EDTM":"2021-02-13 15:01:33","TRT02SDTM":"2021-02-13 15:01:33","TRT02EDTM":"2022-02-13 21:01:33","AP01SDTM":"2019-07-06 20:54:49","AP01EDTM":"2021-02-13 15:01:33","AP02SDTM":"2021-02-13 15:01:33","AP02EDTM":"2022-02-13 21:01:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":954,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-06","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2100,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.65,"AVALU":"mg/L","BASE2":8.65,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-11 20:54:49","ADY":36,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-329","SUBJID":"id-329","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.07281,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-03","TRTSDTM":"2019-07-06 20:54:49","TRTEDTM":"2022-02-13 21:01:33","TRT01SDTM":"2019-07-06 20:54:49","TRT01EDTM":"2021-02-13 15:01:33","TRT02SDTM":"2021-02-13 15:01:33","TRT02EDTM":"2022-02-13 21:01:33","AP01SDTM":"2019-07-06 20:54:49","AP01EDTM":"2021-02-13 15:01:33","AP02SDTM":"2021-02-13 15:01:33","AP02EDTM":"2022-02-13 21:01:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":954,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-06","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6189,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.52297,"AVALU":"mg/L","BASE2":8.65,"BASE":9.52297,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.87297,"PCHG2":10.09213,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-26 20:54:49","ADY":173,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-329","SUBJID":"id-329","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.07281,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-03","TRTSDTM":"2019-07-06 20:54:49","TRTEDTM":"2022-02-13 21:01:33","TRT01SDTM":"2019-07-06 20:54:49","TRT01EDTM":"2021-02-13 15:01:33","TRT02SDTM":"2021-02-13 15:01:33","TRT02EDTM":"2022-02-13 21:01:33","AP01SDTM":"2019-07-06 20:54:49","AP01EDTM":"2021-02-13 15:01:33","AP02SDTM":"2021-02-13 15:01:33","AP02EDTM":"2022-02-13 21:01:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":954,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-06","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7670,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.98391,"AVALU":"mg/L","BASE2":8.65,"BASE":9.52297,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.66608,"PCHG2":-7.7004,"CHG":-1.53905,"PCHG":-16.1615,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-05-07 20:54:49","ADY":306,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-329","SUBJID":"id-329","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.07281,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-03","TRTSDTM":"2019-07-06 20:54:49","TRTEDTM":"2022-02-13 21:01:33","TRT01SDTM":"2019-07-06 20:54:49","TRT01EDTM":"2021-02-13 15:01:33","TRT02SDTM":"2021-02-13 15:01:33","TRT02EDTM":"2022-02-13 21:01:33","AP01SDTM":"2019-07-06 20:54:49","AP01EDTM":"2021-02-13 15:01:33","AP02SDTM":"2021-02-13 15:01:33","AP02EDTM":"2022-02-13 21:01:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":954,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-06","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6690,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.62269,"AVALU":"mg/L","BASE2":8.65,"BASE":9.52297,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.0273,"PCHG2":-11.87636,"CHG":-1.90027,"PCHG":-19.95464,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-08-03 20:54:49","ADY":394,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-329","SUBJID":"id-329","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.07281,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-03","TRTSDTM":"2019-07-06 20:54:49","TRTEDTM":"2022-02-13 21:01:33","TRT01SDTM":"2019-07-06 20:54:49","TRT01EDTM":"2021-02-13 15:01:33","TRT02SDTM":"2021-02-13 15:01:33","TRT02EDTM":"2022-02-13 21:01:33","AP01SDTM":"2019-07-06 20:54:49","AP01EDTM":"2021-02-13 15:01:33","AP02SDTM":"2021-02-13 15:01:33","AP02EDTM":"2022-02-13 21:01:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":954,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-06","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":587,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.15147,"AVALU":"mg/L","BASE2":8.65,"BASE":9.52297,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.49853,"PCHG2":-5.76337,"CHG":-1.3715,"PCHG":-14.40203,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-28 20:54:49","ADY":603,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-329","SUBJID":"id-329","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.07281,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-03","TRTSDTM":"2019-07-06 20:54:49","TRTEDTM":"2022-02-13 21:01:33","TRT01SDTM":"2019-07-06 20:54:49","TRT01EDTM":"2021-02-13 15:01:33","TRT02SDTM":"2021-02-13 15:01:33","TRT02EDTM":"2022-02-13 21:01:33","AP01SDTM":"2019-07-06 20:54:49","AP01EDTM":"2021-02-13 15:01:33","AP02SDTM":"2021-02-13 15:01:33","AP02EDTM":"2022-02-13 21:01:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":954,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-06","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5728,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.11503,"AVALU":"mg/L","BASE2":8.65,"BASE":9.52297,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.46503,"PCHG2":16.93679,"CHG":0.59206,"PCHG":6.21721,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-03-13 20:54:49","ADY":616,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-329","SUBJID":"id-329","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.07281,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-03","TRTSDTM":"2019-07-06 20:54:49","TRTEDTM":"2022-02-13 21:01:33","TRT01SDTM":"2019-07-06 20:54:49","TRT01EDTM":"2021-02-13 15:01:33","TRT02SDTM":"2021-02-13 15:01:33","TRT02EDTM":"2022-02-13 21:01:33","AP01SDTM":"2019-07-06 20:54:49","AP01EDTM":"2021-02-13 15:01:33","AP02SDTM":"2021-02-13 15:01:33","AP02EDTM":"2022-02-13 21:01:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":954,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-06","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4321,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.90654,"AVALU":"mg/L","BASE2":8.65,"BASE":9.52297,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.25654,"PCHG2":2.96578,"CHG":-0.61643,"PCHG":-6.47308,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-26 20:54:49","ADY":660,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-329","SUBJID":"id-329","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.07281,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-03","TRTSDTM":"2019-07-06 20:54:49","TRTEDTM":"2022-02-13 21:01:33","TRT01SDTM":"2019-07-06 20:54:49","TRT01EDTM":"2021-02-13 15:01:33","TRT02SDTM":"2021-02-13 15:01:33","TRT02EDTM":"2022-02-13 21:01:33","AP01SDTM":"2019-07-06 20:54:49","AP01EDTM":"2021-02-13 15:01:33","AP02SDTM":"2021-02-13 15:01:33","AP02EDTM":"2022-02-13 21:01:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":954,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-06","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4422,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88494,"AVALU":"g/L","BASE2":2.88494,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-11 20:54:49","ADY":36,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-329","SUBJID":"id-329","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.07281,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-03","TRTSDTM":"2019-07-06 20:54:49","TRTEDTM":"2022-02-13 21:01:33","TRT01SDTM":"2019-07-06 20:54:49","TRT01EDTM":"2021-02-13 15:01:33","TRT02SDTM":"2021-02-13 15:01:33","TRT02EDTM":"2022-02-13 21:01:33","AP01SDTM":"2019-07-06 20:54:49","AP01EDTM":"2021-02-13 15:01:33","AP02SDTM":"2021-02-13 15:01:33","AP02EDTM":"2022-02-13 21:01:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":954,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-06","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6090,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79741,"AVALU":"g/L","BASE2":2.88494,"BASE":2.79741,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.08753,"PCHG2":-3.03417,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-26 20:54:49","ADY":173,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-329","SUBJID":"id-329","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.07281,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-03","TRTSDTM":"2019-07-06 20:54:49","TRTEDTM":"2022-02-13 21:01:33","TRT01SDTM":"2019-07-06 20:54:49","TRT01EDTM":"2021-02-13 15:01:33","TRT02SDTM":"2021-02-13 15:01:33","TRT02EDTM":"2022-02-13 21:01:33","AP01SDTM":"2019-07-06 20:54:49","AP01EDTM":"2021-02-13 15:01:33","AP02SDTM":"2021-02-13 15:01:33","AP02EDTM":"2022-02-13 21:01:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":954,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-06","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4526,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.07705,"AVALU":"g/L","BASE2":2.88494,"BASE":2.79741,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.19211,"PCHG2":6.65907,"CHG":0.27964,"PCHG":9.99656,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-05-07 20:54:49","ADY":306,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-329","SUBJID":"id-329","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.07281,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-03","TRTSDTM":"2019-07-06 20:54:49","TRTEDTM":"2022-02-13 21:01:33","TRT01SDTM":"2019-07-06 20:54:49","TRT01EDTM":"2021-02-13 15:01:33","TRT02SDTM":"2021-02-13 15:01:33","TRT02EDTM":"2022-02-13 21:01:33","AP01SDTM":"2019-07-06 20:54:49","AP01EDTM":"2021-02-13 15:01:33","AP02SDTM":"2021-02-13 15:01:33","AP02EDTM":"2022-02-13 21:01:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":954,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-06","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":949,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97651,"AVALU":"g/L","BASE2":2.88494,"BASE":2.79741,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09157,"PCHG2":3.17408,"CHG":0.1791,"PCHG":6.40252,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-03 20:54:49","ADY":394,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-329","SUBJID":"id-329","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.07281,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-03","TRTSDTM":"2019-07-06 20:54:49","TRTEDTM":"2022-02-13 21:01:33","TRT01SDTM":"2019-07-06 20:54:49","TRT01EDTM":"2021-02-13 15:01:33","TRT02SDTM":"2021-02-13 15:01:33","TRT02EDTM":"2022-02-13 21:01:33","AP01SDTM":"2019-07-06 20:54:49","AP01EDTM":"2021-02-13 15:01:33","AP02SDTM":"2021-02-13 15:01:33","AP02EDTM":"2022-02-13 21:01:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":954,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-06","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1770,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81172,"AVALU":"g/L","BASE2":2.88494,"BASE":2.79741,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07322,"PCHG2":-2.53808,"CHG":0.01431,"PCHG":0.51162,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-28 20:54:49","ADY":603,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-329","SUBJID":"id-329","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.07281,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-03","TRTSDTM":"2019-07-06 20:54:49","TRTEDTM":"2022-02-13 21:01:33","TRT01SDTM":"2019-07-06 20:54:49","TRT01EDTM":"2021-02-13 15:01:33","TRT02SDTM":"2021-02-13 15:01:33","TRT02EDTM":"2022-02-13 21:01:33","AP01SDTM":"2019-07-06 20:54:49","AP01EDTM":"2021-02-13 15:01:33","AP02SDTM":"2021-02-13 15:01:33","AP02EDTM":"2022-02-13 21:01:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":954,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-06","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6769,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98166,"AVALU":"g/L","BASE2":2.88494,"BASE":2.79741,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09672,"PCHG2":3.35254,"CHG":0.18425,"PCHG":6.58656,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-13 20:54:49","ADY":616,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-329","SUBJID":"id-329","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.07281,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-03","TRTSDTM":"2019-07-06 20:54:49","TRTEDTM":"2022-02-13 21:01:33","TRT01SDTM":"2019-07-06 20:54:49","TRT01EDTM":"2021-02-13 15:01:33","TRT02SDTM":"2021-02-13 15:01:33","TRT02EDTM":"2022-02-13 21:01:33","AP01SDTM":"2019-07-06 20:54:49","AP01EDTM":"2021-02-13 15:01:33","AP02SDTM":"2021-02-13 15:01:33","AP02EDTM":"2022-02-13 21:01:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":954,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-06","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3865,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91354,"AVALU":"g/L","BASE2":2.88494,"BASE":2.79741,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02859,"PCHG2":0.99111,"CHG":0.11613,"PCHG":4.15124,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-26 20:54:49","ADY":660,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-33","SUBJID":"id-33","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.68515,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-19 03:04:30","TRTEDTM":"2023-12-19 21:04:30","TRT01SDTM":"2020-12-19 03:04:30","TRT01EDTM":"2022-12-19 15:04:30","TRT02SDTM":"2022-12-19 15:04:30","TRT02EDTM":"2023-12-19 21:04:30","AP01SDTM":"2020-12-19 03:04:30","AP01EDTM":"2022-12-19 15:04:30","AP02SDTM":"2022-12-19 15:04:30","AP02EDTM":"2023-12-19 21:04:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-19","EOSDY":1096,"LSTALVDT":"2024-01-09","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6654,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.67952,"AVALU":"U/L","BASE2":23.67952,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-14 03:04:30","ADY":85,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-33","SUBJID":"id-33","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.68515,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-19 03:04:30","TRTEDTM":"2023-12-19 21:04:30","TRT01SDTM":"2020-12-19 03:04:30","TRT01EDTM":"2022-12-19 15:04:30","TRT02SDTM":"2022-12-19 15:04:30","TRT02EDTM":"2023-12-19 21:04:30","AP01SDTM":"2020-12-19 03:04:30","AP01EDTM":"2022-12-19 15:04:30","AP02SDTM":"2022-12-19 15:04:30","AP02EDTM":"2023-12-19 21:04:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-19","EOSDY":1096,"LSTALVDT":"2024-01-09","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1013,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.35211,"AVALU":"U/L","BASE2":23.67952,"BASE":22.35211,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.32741,"PCHG2":-5.60575,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-15 03:04:30","ADY":117,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-33","SUBJID":"id-33","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.68515,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-19 03:04:30","TRTEDTM":"2023-12-19 21:04:30","TRT01SDTM":"2020-12-19 03:04:30","TRT01EDTM":"2022-12-19 15:04:30","TRT02SDTM":"2022-12-19 15:04:30","TRT02EDTM":"2023-12-19 21:04:30","AP01SDTM":"2020-12-19 03:04:30","AP01EDTM":"2022-12-19 15:04:30","AP02SDTM":"2022-12-19 15:04:30","AP02EDTM":"2023-12-19 21:04:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-19","EOSDY":1096,"LSTALVDT":"2024-01-09","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3631,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.02428,"AVALU":"U/L","BASE2":23.67952,"BASE":22.35211,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.65524,"PCHG2":-11.21324,"CHG":-1.32783,"PCHG":-5.9405,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-05 03:04:30","ADY":321,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-33","SUBJID":"id-33","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.68515,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-19 03:04:30","TRTEDTM":"2023-12-19 21:04:30","TRT01SDTM":"2020-12-19 03:04:30","TRT01EDTM":"2022-12-19 15:04:30","TRT02SDTM":"2022-12-19 15:04:30","TRT02EDTM":"2023-12-19 21:04:30","AP01SDTM":"2020-12-19 03:04:30","AP01EDTM":"2022-12-19 15:04:30","AP02SDTM":"2022-12-19 15:04:30","AP02EDTM":"2023-12-19 21:04:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-19","EOSDY":1096,"LSTALVDT":"2024-01-09","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7291,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.91616,"AVALU":"U/L","BASE2":23.67952,"BASE":22.35211,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.23664,"PCHG2":17.89157,"CHG":5.56405,"PCHG":24.89275,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-04 03:04:30","ADY":562,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-33","SUBJID":"id-33","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.68515,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-19 03:04:30","TRTEDTM":"2023-12-19 21:04:30","TRT01SDTM":"2020-12-19 03:04:30","TRT01EDTM":"2022-12-19 15:04:30","TRT02SDTM":"2022-12-19 15:04:30","TRT02EDTM":"2023-12-19 21:04:30","AP01SDTM":"2020-12-19 03:04:30","AP01EDTM":"2022-12-19 15:04:30","AP02SDTM":"2022-12-19 15:04:30","AP02EDTM":"2023-12-19 21:04:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-19","EOSDY":1096,"LSTALVDT":"2024-01-09","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":490,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.61685,"AVALU":"U/L","BASE2":23.67952,"BASE":22.35211,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.06267,"PCHG2":-25.60302,"CHG":-4.73526,"PCHG":-21.18484,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-28 03:04:30","ADY":648,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-33","SUBJID":"id-33","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.68515,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-19 03:04:30","TRTEDTM":"2023-12-19 21:04:30","TRT01SDTM":"2020-12-19 03:04:30","TRT01EDTM":"2022-12-19 15:04:30","TRT02SDTM":"2022-12-19 15:04:30","TRT02EDTM":"2023-12-19 21:04:30","AP01SDTM":"2020-12-19 03:04:30","AP01EDTM":"2022-12-19 15:04:30","AP02SDTM":"2022-12-19 15:04:30","AP02EDTM":"2023-12-19 21:04:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-19","EOSDY":1096,"LSTALVDT":"2024-01-09","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7988,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.38579,"AVALU":"U/L","BASE2":23.67952,"BASE":22.35211,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-23.29373,"PCHG2":-98.3708,"CHG":-21.96632,"PCHG":-98.27405,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2022-11-26 03:04:30","ADY":707,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-33","SUBJID":"id-33","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.68515,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-19 03:04:30","TRTEDTM":"2023-12-19 21:04:30","TRT01SDTM":"2020-12-19 03:04:30","TRT01EDTM":"2022-12-19 15:04:30","TRT02SDTM":"2022-12-19 15:04:30","TRT02EDTM":"2023-12-19 21:04:30","AP01SDTM":"2020-12-19 03:04:30","AP01EDTM":"2022-12-19 15:04:30","AP02SDTM":"2022-12-19 15:04:30","AP02EDTM":"2023-12-19 21:04:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-19","EOSDY":1096,"LSTALVDT":"2024-01-09","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5628,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.47882,"AVALU":"U/L","BASE2":23.67952,"BASE":22.35211,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-19.2007,"PCHG2":-81.08569,"CHG":-17.87329,"PCHG":-79.96243,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2023-05-19 03:04:30","ADY":881,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-33","SUBJID":"id-33","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.68515,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-19 03:04:30","TRTEDTM":"2023-12-19 21:04:30","TRT01SDTM":"2020-12-19 03:04:30","TRT01EDTM":"2022-12-19 15:04:30","TRT02SDTM":"2022-12-19 15:04:30","TRT02EDTM":"2023-12-19 21:04:30","AP01SDTM":"2020-12-19 03:04:30","AP01EDTM":"2022-12-19 15:04:30","AP02SDTM":"2022-12-19 15:04:30","AP02EDTM":"2023-12-19 21:04:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-19","EOSDY":1096,"LSTALVDT":"2024-01-09","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4817,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.70462,"AVALU":"mg/L","BASE2":9.70462,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-03-14 03:04:30","ADY":85,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-33","SUBJID":"id-33","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.68515,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-19 03:04:30","TRTEDTM":"2023-12-19 21:04:30","TRT01SDTM":"2020-12-19 03:04:30","TRT01EDTM":"2022-12-19 15:04:30","TRT02SDTM":"2022-12-19 15:04:30","TRT02EDTM":"2023-12-19 21:04:30","AP01SDTM":"2020-12-19 03:04:30","AP01EDTM":"2022-12-19 15:04:30","AP02SDTM":"2022-12-19 15:04:30","AP02EDTM":"2023-12-19 21:04:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-19","EOSDY":1096,"LSTALVDT":"2024-01-09","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7867,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.66576,"AVALU":"mg/L","BASE2":9.70462,"BASE":7.66576,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.03886,"PCHG2":-21.0092,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2021-04-15 03:04:30","ADY":117,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-33","SUBJID":"id-33","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.68515,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-19 03:04:30","TRTEDTM":"2023-12-19 21:04:30","TRT01SDTM":"2020-12-19 03:04:30","TRT01EDTM":"2022-12-19 15:04:30","TRT02SDTM":"2022-12-19 15:04:30","TRT02EDTM":"2023-12-19 21:04:30","AP01SDTM":"2020-12-19 03:04:30","AP01EDTM":"2022-12-19 15:04:30","AP02SDTM":"2022-12-19 15:04:30","AP02EDTM":"2023-12-19 21:04:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-19","EOSDY":1096,"LSTALVDT":"2024-01-09","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5966,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.92902,"AVALU":"mg/L","BASE2":9.70462,"BASE":7.66576,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.7756,"PCHG2":-7.99202,"CHG":1.26327,"PCHG":16.47937,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-11-05 03:04:30","ADY":321,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-33","SUBJID":"id-33","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.68515,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-19 03:04:30","TRTEDTM":"2023-12-19 21:04:30","TRT01SDTM":"2020-12-19 03:04:30","TRT01EDTM":"2022-12-19 15:04:30","TRT02SDTM":"2022-12-19 15:04:30","TRT02EDTM":"2023-12-19 21:04:30","AP01SDTM":"2020-12-19 03:04:30","AP01EDTM":"2022-12-19 15:04:30","AP02SDTM":"2022-12-19 15:04:30","AP02EDTM":"2023-12-19 21:04:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-19","EOSDY":1096,"LSTALVDT":"2024-01-09","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7294,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.26191,"AVALU":"mg/L","BASE2":9.70462,"BASE":7.66576,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.44271,"PCHG2":-4.56183,"CHG":1.59615,"PCHG":20.82188,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-07-04 03:04:30","ADY":562,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-33","SUBJID":"id-33","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.68515,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-19 03:04:30","TRTEDTM":"2023-12-19 21:04:30","TRT01SDTM":"2020-12-19 03:04:30","TRT01EDTM":"2022-12-19 15:04:30","TRT02SDTM":"2022-12-19 15:04:30","TRT02EDTM":"2023-12-19 21:04:30","AP01SDTM":"2020-12-19 03:04:30","AP01EDTM":"2022-12-19 15:04:30","AP02SDTM":"2022-12-19 15:04:30","AP02EDTM":"2023-12-19 21:04:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-19","EOSDY":1096,"LSTALVDT":"2024-01-09","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5802,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.7007,"AVALU":"mg/L","BASE2":9.70462,"BASE":7.66576,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.00392,"PCHG2":-10.34476,"CHG":1.03494,"PCHG":13.50087,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-09-28 03:04:30","ADY":648,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-33","SUBJID":"id-33","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.68515,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-19 03:04:30","TRTEDTM":"2023-12-19 21:04:30","TRT01SDTM":"2020-12-19 03:04:30","TRT01EDTM":"2022-12-19 15:04:30","TRT02SDTM":"2022-12-19 15:04:30","TRT02EDTM":"2023-12-19 21:04:30","AP01SDTM":"2020-12-19 03:04:30","AP01EDTM":"2022-12-19 15:04:30","AP02SDTM":"2022-12-19 15:04:30","AP02EDTM":"2023-12-19 21:04:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-19","EOSDY":1096,"LSTALVDT":"2024-01-09","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6474,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.29871,"AVALU":"mg/L","BASE2":9.70462,"BASE":7.66576,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.40591,"PCHG2":-14.48699,"CHG":0.63296,"PCHG":8.25692,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-11-26 03:04:30","ADY":707,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-33","SUBJID":"id-33","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.68515,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-19 03:04:30","TRTEDTM":"2023-12-19 21:04:30","TRT01SDTM":"2020-12-19 03:04:30","TRT01EDTM":"2022-12-19 15:04:30","TRT02SDTM":"2022-12-19 15:04:30","TRT02EDTM":"2023-12-19 21:04:30","AP01SDTM":"2020-12-19 03:04:30","AP01EDTM":"2022-12-19 15:04:30","AP02SDTM":"2022-12-19 15:04:30","AP02EDTM":"2023-12-19 21:04:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-19","EOSDY":1096,"LSTALVDT":"2024-01-09","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6750,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.48366,"AVALU":"mg/L","BASE2":9.70462,"BASE":7.66576,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.22096,"PCHG2":-12.58118,"CHG":0.81791,"PCHG":10.66963,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2023-05-19 03:04:30","ADY":881,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-33","SUBJID":"id-33","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.68515,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-19 03:04:30","TRTEDTM":"2023-12-19 21:04:30","TRT01SDTM":"2020-12-19 03:04:30","TRT01EDTM":"2022-12-19 15:04:30","TRT02SDTM":"2022-12-19 15:04:30","TRT02EDTM":"2023-12-19 21:04:30","AP01SDTM":"2020-12-19 03:04:30","AP01EDTM":"2022-12-19 15:04:30","AP02SDTM":"2022-12-19 15:04:30","AP02EDTM":"2023-12-19 21:04:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-19","EOSDY":1096,"LSTALVDT":"2024-01-09","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":170,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80286,"AVALU":"g/L","BASE2":2.80286,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-14 03:04:30","ADY":85,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-33","SUBJID":"id-33","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.68515,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-19 03:04:30","TRTEDTM":"2023-12-19 21:04:30","TRT01SDTM":"2020-12-19 03:04:30","TRT01EDTM":"2022-12-19 15:04:30","TRT02SDTM":"2022-12-19 15:04:30","TRT02EDTM":"2023-12-19 21:04:30","AP01SDTM":"2020-12-19 03:04:30","AP01EDTM":"2022-12-19 15:04:30","AP02SDTM":"2022-12-19 15:04:30","AP02EDTM":"2023-12-19 21:04:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-19","EOSDY":1096,"LSTALVDT":"2024-01-09","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1104,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76155,"AVALU":"g/L","BASE2":2.80286,"BASE":2.76155,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.04131,"PCHG2":-1.47391,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-15 03:04:30","ADY":117,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-33","SUBJID":"id-33","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.68515,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-19 03:04:30","TRTEDTM":"2023-12-19 21:04:30","TRT01SDTM":"2020-12-19 03:04:30","TRT01EDTM":"2022-12-19 15:04:30","TRT02SDTM":"2022-12-19 15:04:30","TRT02EDTM":"2023-12-19 21:04:30","AP01SDTM":"2020-12-19 03:04:30","AP01EDTM":"2022-12-19 15:04:30","AP02SDTM":"2022-12-19 15:04:30","AP02EDTM":"2023-12-19 21:04:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-19","EOSDY":1096,"LSTALVDT":"2024-01-09","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3872,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86512,"AVALU":"g/L","BASE2":2.80286,"BASE":2.76155,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06226,"PCHG2":2.22137,"CHG":0.10357,"PCHG":3.75056,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-05 03:04:30","ADY":321,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-33","SUBJID":"id-33","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.68515,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-19 03:04:30","TRTEDTM":"2023-12-19 21:04:30","TRT01SDTM":"2020-12-19 03:04:30","TRT01EDTM":"2022-12-19 15:04:30","TRT02SDTM":"2022-12-19 15:04:30","TRT02EDTM":"2023-12-19 21:04:30","AP01SDTM":"2020-12-19 03:04:30","AP01EDTM":"2022-12-19 15:04:30","AP02SDTM":"2022-12-19 15:04:30","AP02EDTM":"2023-12-19 21:04:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-19","EOSDY":1096,"LSTALVDT":"2024-01-09","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5891,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87908,"AVALU":"g/L","BASE2":2.80286,"BASE":2.76155,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07622,"PCHG2":2.71937,"CHG":0.11753,"PCHG":4.25601,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-04 03:04:30","ADY":562,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-33","SUBJID":"id-33","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.68515,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-19 03:04:30","TRTEDTM":"2023-12-19 21:04:30","TRT01SDTM":"2020-12-19 03:04:30","TRT01EDTM":"2022-12-19 15:04:30","TRT02SDTM":"2022-12-19 15:04:30","TRT02EDTM":"2023-12-19 21:04:30","AP01SDTM":"2020-12-19 03:04:30","AP01EDTM":"2022-12-19 15:04:30","AP02SDTM":"2022-12-19 15:04:30","AP02EDTM":"2023-12-19 21:04:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-19","EOSDY":1096,"LSTALVDT":"2024-01-09","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2993,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00448,"AVALU":"g/L","BASE2":2.80286,"BASE":2.76155,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.20162,"PCHG2":7.19351,"CHG":0.24294,"PCHG":8.79708,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-09-28 03:04:30","ADY":648,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-33","SUBJID":"id-33","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.68515,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-19 03:04:30","TRTEDTM":"2023-12-19 21:04:30","TRT01SDTM":"2020-12-19 03:04:30","TRT01EDTM":"2022-12-19 15:04:30","TRT02SDTM":"2022-12-19 15:04:30","TRT02EDTM":"2023-12-19 21:04:30","AP01SDTM":"2020-12-19 03:04:30","AP01EDTM":"2022-12-19 15:04:30","AP02SDTM":"2022-12-19 15:04:30","AP02EDTM":"2023-12-19 21:04:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-19","EOSDY":1096,"LSTALVDT":"2024-01-09","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5483,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93441,"AVALU":"g/L","BASE2":2.80286,"BASE":2.76155,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13155,"PCHG2":4.69337,"CHG":0.17286,"PCHG":6.25953,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-26 03:04:30","ADY":707,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-33","SUBJID":"id-33","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.68515,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-19 03:04:30","TRTEDTM":"2023-12-19 21:04:30","TRT01SDTM":"2020-12-19 03:04:30","TRT01EDTM":"2022-12-19 15:04:30","TRT02SDTM":"2022-12-19 15:04:30","TRT02EDTM":"2023-12-19 21:04:30","AP01SDTM":"2020-12-19 03:04:30","AP01EDTM":"2022-12-19 15:04:30","AP02SDTM":"2022-12-19 15:04:30","AP02EDTM":"2023-12-19 21:04:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-19","EOSDY":1096,"LSTALVDT":"2024-01-09","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7798,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.68384,"AVALU":"g/L","BASE2":2.80286,"BASE":2.76155,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11902,"PCHG2":-4.24641,"CHG":-0.07771,"PCHG":-2.81398,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-19 03:04:30","ADY":881,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-336","SUBJID":"id-336","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 00:07:59","TRTEDTM":"2023-08-24 18:07:59","TRT01SDTM":"2020-08-24 00:07:59","TRT01EDTM":"2022-08-24 12:07:59","TRT02SDTM":"2022-08-24 12:07:59","TRT02EDTM":"2023-08-24 18:07:59","AP01SDTM":"2020-08-24 00:07:59","AP01EDTM":"2022-08-24 12:07:59","AP02SDTM":"2022-08-24 12:07:59","AP02EDTM":"2023-08-24 18:07:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-24","EOSDY":1096,"LSTALVDT":"2023-09-06","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4600,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.52702,"AVALU":"U/L","BASE2":7.52702,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-17 00:07:59","ADY":146,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-336","SUBJID":"id-336","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 00:07:59","TRTEDTM":"2023-08-24 18:07:59","TRT01SDTM":"2020-08-24 00:07:59","TRT01EDTM":"2022-08-24 12:07:59","TRT02SDTM":"2022-08-24 12:07:59","TRT02EDTM":"2023-08-24 18:07:59","AP01SDTM":"2020-08-24 00:07:59","AP01EDTM":"2022-08-24 12:07:59","AP02SDTM":"2022-08-24 12:07:59","AP02EDTM":"2023-08-24 18:07:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-24","EOSDY":1096,"LSTALVDT":"2023-09-06","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4297,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.74687,"AVALU":"U/L","BASE2":7.52702,"BASE":8.74687,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.21985,"PCHG2":16.2063,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-08 00:07:59","ADY":168,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-336","SUBJID":"id-336","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 00:07:59","TRTEDTM":"2023-08-24 18:07:59","TRT01SDTM":"2020-08-24 00:07:59","TRT01EDTM":"2022-08-24 12:07:59","TRT02SDTM":"2022-08-24 12:07:59","TRT02EDTM":"2023-08-24 18:07:59","AP01SDTM":"2020-08-24 00:07:59","AP01EDTM":"2022-08-24 12:07:59","AP02SDTM":"2022-08-24 12:07:59","AP02EDTM":"2023-08-24 18:07:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-24","EOSDY":1096,"LSTALVDT":"2023-09-06","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2952,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":37.40672,"AVALU":"U/L","BASE2":7.52702,"BASE":8.74687,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":29.8797,"PCHG2":396.9659,"CHG":28.65985,"PCHG":327.65829,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-04 00:07:59","ADY":192,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-336","SUBJID":"id-336","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 00:07:59","TRTEDTM":"2023-08-24 18:07:59","TRT01SDTM":"2020-08-24 00:07:59","TRT01EDTM":"2022-08-24 12:07:59","TRT02SDTM":"2022-08-24 12:07:59","TRT02EDTM":"2023-08-24 18:07:59","AP01SDTM":"2020-08-24 00:07:59","AP01EDTM":"2022-08-24 12:07:59","AP02SDTM":"2022-08-24 12:07:59","AP02EDTM":"2023-08-24 18:07:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-24","EOSDY":1096,"LSTALVDT":"2023-09-06","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1904,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.07699,"AVALU":"U/L","BASE2":7.52702,"BASE":8.74687,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.54997,"PCHG2":153.44684,"CHG":10.33012,"PCHG":118.10077,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-12 00:07:59","ADY":445,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-336","SUBJID":"id-336","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 00:07:59","TRTEDTM":"2023-08-24 18:07:59","TRT01SDTM":"2020-08-24 00:07:59","TRT01EDTM":"2022-08-24 12:07:59","TRT02SDTM":"2022-08-24 12:07:59","TRT02EDTM":"2023-08-24 18:07:59","AP01SDTM":"2020-08-24 00:07:59","AP01EDTM":"2022-08-24 12:07:59","AP02SDTM":"2022-08-24 12:07:59","AP02EDTM":"2023-08-24 18:07:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-24","EOSDY":1096,"LSTALVDT":"2023-09-06","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6045,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.78713,"AVALU":"U/L","BASE2":7.52702,"BASE":8.74687,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":24.26011,"PCHG2":322.30702,"CHG":23.04026,"PCHG":263.41146,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-24 00:07:59","ADY":549,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-336","SUBJID":"id-336","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 00:07:59","TRTEDTM":"2023-08-24 18:07:59","TRT01SDTM":"2020-08-24 00:07:59","TRT01EDTM":"2022-08-24 12:07:59","TRT02SDTM":"2022-08-24 12:07:59","TRT02EDTM":"2023-08-24 18:07:59","AP01SDTM":"2020-08-24 00:07:59","AP01EDTM":"2022-08-24 12:07:59","AP02SDTM":"2022-08-24 12:07:59","AP02EDTM":"2023-08-24 18:07:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-24","EOSDY":1096,"LSTALVDT":"2023-09-06","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":942,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.67381,"AVALU":"U/L","BASE2":7.52702,"BASE":8.74687,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.14679,"PCHG2":214.51772,"CHG":14.92694,"PCHG":170.65461,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-08 00:07:59","ADY":561,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-336","SUBJID":"id-336","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 00:07:59","TRTEDTM":"2023-08-24 18:07:59","TRT01SDTM":"2020-08-24 00:07:59","TRT01EDTM":"2022-08-24 12:07:59","TRT02SDTM":"2022-08-24 12:07:59","TRT02EDTM":"2023-08-24 18:07:59","AP01SDTM":"2020-08-24 00:07:59","AP01EDTM":"2022-08-24 12:07:59","AP02SDTM":"2022-08-24 12:07:59","AP02EDTM":"2023-08-24 18:07:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-24","EOSDY":1096,"LSTALVDT":"2023-09-06","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1949,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.06085,"AVALU":"U/L","BASE2":7.52702,"BASE":8.74687,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.53383,"PCHG2":219.65972,"CHG":15.31398,"PCHG":175.0795,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-24 00:07:59","ADY":577,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-336","SUBJID":"id-336","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 00:07:59","TRTEDTM":"2023-08-24 18:07:59","TRT01SDTM":"2020-08-24 00:07:59","TRT01EDTM":"2022-08-24 12:07:59","TRT02SDTM":"2022-08-24 12:07:59","TRT02EDTM":"2023-08-24 18:07:59","AP01SDTM":"2020-08-24 00:07:59","AP01EDTM":"2022-08-24 12:07:59","AP02SDTM":"2022-08-24 12:07:59","AP02EDTM":"2023-08-24 18:07:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-24","EOSDY":1096,"LSTALVDT":"2023-09-06","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1615,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.31345,"AVALU":"mg/L","BASE2":10.31345,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-01-17 00:07:59","ADY":146,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-336","SUBJID":"id-336","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 00:07:59","TRTEDTM":"2023-08-24 18:07:59","TRT01SDTM":"2020-08-24 00:07:59","TRT01EDTM":"2022-08-24 12:07:59","TRT02SDTM":"2022-08-24 12:07:59","TRT02EDTM":"2023-08-24 18:07:59","AP01SDTM":"2020-08-24 00:07:59","AP01EDTM":"2022-08-24 12:07:59","AP02SDTM":"2022-08-24 12:07:59","AP02EDTM":"2023-08-24 18:07:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-24","EOSDY":1096,"LSTALVDT":"2023-09-06","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4736,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.26419,"AVALU":"mg/L","BASE2":10.31345,"BASE":9.26419,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.04926,"PCHG2":-10.17368,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-08 00:07:59","ADY":168,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-336","SUBJID":"id-336","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 00:07:59","TRTEDTM":"2023-08-24 18:07:59","TRT01SDTM":"2020-08-24 00:07:59","TRT01EDTM":"2022-08-24 12:07:59","TRT02SDTM":"2022-08-24 12:07:59","TRT02EDTM":"2023-08-24 18:07:59","AP01SDTM":"2020-08-24 00:07:59","AP01EDTM":"2022-08-24 12:07:59","AP02SDTM":"2022-08-24 12:07:59","AP02EDTM":"2023-08-24 18:07:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-24","EOSDY":1096,"LSTALVDT":"2023-09-06","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1689,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.98996,"AVALU":"mg/L","BASE2":10.31345,"BASE":9.26419,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.32349,"PCHG2":-22.52871,"CHG":-1.27423,"PCHG":-13.75435,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-03-04 00:07:59","ADY":192,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-336","SUBJID":"id-336","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 00:07:59","TRTEDTM":"2023-08-24 18:07:59","TRT01SDTM":"2020-08-24 00:07:59","TRT01EDTM":"2022-08-24 12:07:59","TRT02SDTM":"2022-08-24 12:07:59","TRT02EDTM":"2023-08-24 18:07:59","AP01SDTM":"2020-08-24 00:07:59","AP01EDTM":"2022-08-24 12:07:59","AP02SDTM":"2022-08-24 12:07:59","AP02EDTM":"2023-08-24 18:07:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-24","EOSDY":1096,"LSTALVDT":"2023-09-06","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4698,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.14928,"AVALU":"mg/L","BASE2":10.31345,"BASE":9.26419,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.16417,"PCHG2":-11.28786,"CHG":-0.11491,"PCHG":-1.24037,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-12 00:07:59","ADY":445,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-336","SUBJID":"id-336","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 00:07:59","TRTEDTM":"2023-08-24 18:07:59","TRT01SDTM":"2020-08-24 00:07:59","TRT01EDTM":"2022-08-24 12:07:59","TRT02SDTM":"2022-08-24 12:07:59","TRT02EDTM":"2023-08-24 18:07:59","AP01SDTM":"2020-08-24 00:07:59","AP01EDTM":"2022-08-24 12:07:59","AP02SDTM":"2022-08-24 12:07:59","AP02EDTM":"2023-08-24 18:07:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-24","EOSDY":1096,"LSTALVDT":"2023-09-06","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3611,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.29012,"AVALU":"mg/L","BASE2":10.31345,"BASE":9.26419,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.02333,"PCHG2":-29.31446,"CHG":-1.97407,"PCHG":-21.30866,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2022-02-24 00:07:59","ADY":549,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-336","SUBJID":"id-336","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 00:07:59","TRTEDTM":"2023-08-24 18:07:59","TRT01SDTM":"2020-08-24 00:07:59","TRT01EDTM":"2022-08-24 12:07:59","TRT02SDTM":"2022-08-24 12:07:59","TRT02EDTM":"2023-08-24 18:07:59","AP01SDTM":"2020-08-24 00:07:59","AP01EDTM":"2022-08-24 12:07:59","AP02SDTM":"2022-08-24 12:07:59","AP02EDTM":"2023-08-24 18:07:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-24","EOSDY":1096,"LSTALVDT":"2023-09-06","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7540,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.76203,"AVALU":"mg/L","BASE2":10.31345,"BASE":9.26419,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.55142,"PCHG2":-5.34662,"CHG":0.49784,"PCHG":5.37377,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-08 00:07:59","ADY":561,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-336","SUBJID":"id-336","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 00:07:59","TRTEDTM":"2023-08-24 18:07:59","TRT01SDTM":"2020-08-24 00:07:59","TRT01EDTM":"2022-08-24 12:07:59","TRT02SDTM":"2022-08-24 12:07:59","TRT02EDTM":"2023-08-24 18:07:59","AP01SDTM":"2020-08-24 00:07:59","AP01EDTM":"2022-08-24 12:07:59","AP02SDTM":"2022-08-24 12:07:59","AP02EDTM":"2023-08-24 18:07:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-24","EOSDY":1096,"LSTALVDT":"2023-09-06","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8315,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.35249,"AVALU":"mg/L","BASE2":10.31345,"BASE":9.26419,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.96096,"PCHG2":-9.3175,"CHG":0.0883,"PCHG":0.95315,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-24 00:07:59","ADY":577,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-336","SUBJID":"id-336","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 00:07:59","TRTEDTM":"2023-08-24 18:07:59","TRT01SDTM":"2020-08-24 00:07:59","TRT01EDTM":"2022-08-24 12:07:59","TRT02SDTM":"2022-08-24 12:07:59","TRT02EDTM":"2023-08-24 18:07:59","AP01SDTM":"2020-08-24 00:07:59","AP01EDTM":"2022-08-24 12:07:59","AP02SDTM":"2022-08-24 12:07:59","AP02EDTM":"2023-08-24 18:07:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-24","EOSDY":1096,"LSTALVDT":"2023-09-06","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3439,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.61023,"AVALU":"g/L","BASE2":2.61023,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-17 00:07:59","ADY":146,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-336","SUBJID":"id-336","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 00:07:59","TRTEDTM":"2023-08-24 18:07:59","TRT01SDTM":"2020-08-24 00:07:59","TRT01EDTM":"2022-08-24 12:07:59","TRT02SDTM":"2022-08-24 12:07:59","TRT02EDTM":"2023-08-24 18:07:59","AP01SDTM":"2020-08-24 00:07:59","AP01EDTM":"2022-08-24 12:07:59","AP02SDTM":"2022-08-24 12:07:59","AP02EDTM":"2023-08-24 18:07:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-24","EOSDY":1096,"LSTALVDT":"2023-09-06","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1791,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.65814,"AVALU":"g/L","BASE2":2.61023,"BASE":2.65814,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.04791,"PCHG2":1.83549,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-08 00:07:59","ADY":168,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-336","SUBJID":"id-336","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 00:07:59","TRTEDTM":"2023-08-24 18:07:59","TRT01SDTM":"2020-08-24 00:07:59","TRT01EDTM":"2022-08-24 12:07:59","TRT02SDTM":"2022-08-24 12:07:59","TRT02EDTM":"2023-08-24 18:07:59","AP01SDTM":"2020-08-24 00:07:59","AP01EDTM":"2022-08-24 12:07:59","AP02SDTM":"2022-08-24 12:07:59","AP02EDTM":"2023-08-24 18:07:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-24","EOSDY":1096,"LSTALVDT":"2023-09-06","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1209,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91445,"AVALU":"g/L","BASE2":2.61023,"BASE":2.65814,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.30423,"PCHG2":11.65514,"CHG":0.25632,"PCHG":9.64266,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-04 00:07:59","ADY":192,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-336","SUBJID":"id-336","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 00:07:59","TRTEDTM":"2023-08-24 18:07:59","TRT01SDTM":"2020-08-24 00:07:59","TRT01EDTM":"2022-08-24 12:07:59","TRT02SDTM":"2022-08-24 12:07:59","TRT02EDTM":"2023-08-24 18:07:59","AP01SDTM":"2020-08-24 00:07:59","AP01EDTM":"2022-08-24 12:07:59","AP02SDTM":"2022-08-24 12:07:59","AP02EDTM":"2023-08-24 18:07:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-24","EOSDY":1096,"LSTALVDT":"2023-09-06","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7409,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91131,"AVALU":"g/L","BASE2":2.61023,"BASE":2.65814,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.30109,"PCHG2":11.5349,"CHG":0.25318,"PCHG":9.52459,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-12 00:07:59","ADY":445,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-336","SUBJID":"id-336","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 00:07:59","TRTEDTM":"2023-08-24 18:07:59","TRT01SDTM":"2020-08-24 00:07:59","TRT01EDTM":"2022-08-24 12:07:59","TRT02SDTM":"2022-08-24 12:07:59","TRT02EDTM":"2023-08-24 18:07:59","AP01SDTM":"2020-08-24 00:07:59","AP01EDTM":"2022-08-24 12:07:59","AP02SDTM":"2022-08-24 12:07:59","AP02EDTM":"2023-08-24 18:07:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-24","EOSDY":1096,"LSTALVDT":"2023-09-06","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3270,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89917,"AVALU":"g/L","BASE2":2.61023,"BASE":2.65814,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.28895,"PCHG2":11.06983,"CHG":0.24104,"PCHG":9.0679,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-24 00:07:59","ADY":549,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-336","SUBJID":"id-336","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 00:07:59","TRTEDTM":"2023-08-24 18:07:59","TRT01SDTM":"2020-08-24 00:07:59","TRT01EDTM":"2022-08-24 12:07:59","TRT02SDTM":"2022-08-24 12:07:59","TRT02EDTM":"2023-08-24 18:07:59","AP01SDTM":"2020-08-24 00:07:59","AP01EDTM":"2022-08-24 12:07:59","AP02SDTM":"2022-08-24 12:07:59","AP02EDTM":"2023-08-24 18:07:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-24","EOSDY":1096,"LSTALVDT":"2023-09-06","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5854,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92819,"AVALU":"g/L","BASE2":2.61023,"BASE":2.65814,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.31796,"PCHG2":12.18142,"CHG":0.27005,"PCHG":10.15945,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-08 00:07:59","ADY":561,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-336","SUBJID":"id-336","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 00:07:59","TRTEDTM":"2023-08-24 18:07:59","TRT01SDTM":"2020-08-24 00:07:59","TRT01EDTM":"2022-08-24 12:07:59","TRT02SDTM":"2022-08-24 12:07:59","TRT02EDTM":"2023-08-24 18:07:59","AP01SDTM":"2020-08-24 00:07:59","AP01EDTM":"2022-08-24 12:07:59","AP02SDTM":"2022-08-24 12:07:59","AP02EDTM":"2023-08-24 18:07:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-24","EOSDY":1096,"LSTALVDT":"2023-09-06","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6434,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86882,"AVALU":"g/L","BASE2":2.61023,"BASE":2.65814,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.2586,"PCHG2":9.90711,"CHG":0.21069,"PCHG":7.92614,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-24 00:07:59","ADY":577,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-337","SUBJID":"id-337","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.22759,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-03","TRTSDTM":"2020-06-05 23:39:55","TRTEDTM":"2023-06-06 17:39:55","TRT01SDTM":"2020-06-05 23:39:55","TRT01EDTM":"2022-06-06 11:39:55","TRT02SDTM":"2022-06-06 11:39:55","TRT02EDTM":"2023-06-06 17:39:55","AP01SDTM":"2020-06-05 23:39:55","AP01EDTM":"2022-06-06 11:39:55","AP02SDTM":"2022-06-06 11:39:55","AP02EDTM":"2023-06-06 17:39:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-06","EOSDY":1096,"LSTALVDT":"2023-07-03","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1121,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":35.19627,"AVALU":"U/L","BASE2":35.19627,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-17 23:39:55","ADY":104,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-337","SUBJID":"id-337","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.22759,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-03","TRTSDTM":"2020-06-05 23:39:55","TRTEDTM":"2023-06-06 17:39:55","TRT01SDTM":"2020-06-05 23:39:55","TRT01EDTM":"2022-06-06 11:39:55","TRT02SDTM":"2022-06-06 11:39:55","TRT02EDTM":"2023-06-06 17:39:55","AP01SDTM":"2020-06-05 23:39:55","AP01EDTM":"2022-06-06 11:39:55","AP02SDTM":"2022-06-06 11:39:55","AP02EDTM":"2023-06-06 17:39:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-06","EOSDY":1096,"LSTALVDT":"2023-07-03","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":608,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.83122,"AVALU":"U/L","BASE2":35.19627,"BASE":9.83122,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-25.36505,"PCHG2":-72.06743,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-26 23:39:55","ADY":235,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-337","SUBJID":"id-337","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.22759,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-03","TRTSDTM":"2020-06-05 23:39:55","TRTEDTM":"2023-06-06 17:39:55","TRT01SDTM":"2020-06-05 23:39:55","TRT01EDTM":"2022-06-06 11:39:55","TRT02SDTM":"2022-06-06 11:39:55","TRT02EDTM":"2023-06-06 17:39:55","AP01SDTM":"2020-06-05 23:39:55","AP01EDTM":"2022-06-06 11:39:55","AP02SDTM":"2022-06-06 11:39:55","AP02EDTM":"2023-06-06 17:39:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-06","EOSDY":1096,"LSTALVDT":"2023-07-03","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5832,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.74707,"AVALU":"U/L","BASE2":35.19627,"BASE":9.83122,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.4492,"PCHG2":-41.05321,"CHG":10.91585,"PCHG":111.03247,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-11 23:39:55","ADY":251,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-337","SUBJID":"id-337","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.22759,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-03","TRTSDTM":"2020-06-05 23:39:55","TRTEDTM":"2023-06-06 17:39:55","TRT01SDTM":"2020-06-05 23:39:55","TRT01EDTM":"2022-06-06 11:39:55","TRT02SDTM":"2022-06-06 11:39:55","TRT02EDTM":"2023-06-06 17:39:55","AP01SDTM":"2020-06-05 23:39:55","AP01EDTM":"2022-06-06 11:39:55","AP02SDTM":"2022-06-06 11:39:55","AP02EDTM":"2023-06-06 17:39:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-06","EOSDY":1096,"LSTALVDT":"2023-07-03","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8374,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.96552,"AVALU":"U/L","BASE2":35.19627,"BASE":9.83122,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.23076,"PCHG2":-26.22651,"CHG":16.13429,"PCHG":164.11276,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-13 23:39:55","ADY":556,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-337","SUBJID":"id-337","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.22759,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-03","TRTSDTM":"2020-06-05 23:39:55","TRTEDTM":"2023-06-06 17:39:55","TRT01SDTM":"2020-06-05 23:39:55","TRT01EDTM":"2022-06-06 11:39:55","TRT02SDTM":"2022-06-06 11:39:55","TRT02EDTM":"2023-06-06 17:39:55","AP01SDTM":"2020-06-05 23:39:55","AP01EDTM":"2022-06-06 11:39:55","AP02SDTM":"2022-06-06 11:39:55","AP02EDTM":"2023-06-06 17:39:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-06","EOSDY":1096,"LSTALVDT":"2023-07-03","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":859,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":38.6073,"AVALU":"U/L","BASE2":35.19627,"BASE":9.83122,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.41103,"PCHG2":9.69146,"CHG":28.77608,"PCHG":292.70089,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-16 23:39:55","ADY":802,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-337","SUBJID":"id-337","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.22759,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-03","TRTSDTM":"2020-06-05 23:39:55","TRTEDTM":"2023-06-06 17:39:55","TRT01SDTM":"2020-06-05 23:39:55","TRT01EDTM":"2022-06-06 11:39:55","TRT02SDTM":"2022-06-06 11:39:55","TRT02EDTM":"2023-06-06 17:39:55","AP01SDTM":"2020-06-05 23:39:55","AP01EDTM":"2022-06-06 11:39:55","AP02SDTM":"2022-06-06 11:39:55","AP02EDTM":"2023-06-06 17:39:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-06","EOSDY":1096,"LSTALVDT":"2023-07-03","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1366,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.36903,"AVALU":"U/L","BASE2":35.19627,"BASE":9.83122,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-29.82724,"PCHG2":-84.74546,"CHG":-4.46219,"PCHG":-45.38799,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2022-11-29 23:39:55","ADY":907,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-337","SUBJID":"id-337","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.22759,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-03","TRTSDTM":"2020-06-05 23:39:55","TRTEDTM":"2023-06-06 17:39:55","TRT01SDTM":"2020-06-05 23:39:55","TRT01EDTM":"2022-06-06 11:39:55","TRT02SDTM":"2022-06-06 11:39:55","TRT02EDTM":"2023-06-06 17:39:55","AP01SDTM":"2020-06-05 23:39:55","AP01EDTM":"2022-06-06 11:39:55","AP02SDTM":"2022-06-06 11:39:55","AP02EDTM":"2023-06-06 17:39:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-06","EOSDY":1096,"LSTALVDT":"2023-07-03","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3676,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.28582,"AVALU":"U/L","BASE2":35.19627,"BASE":9.83122,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.91045,"PCHG2":-11.11042,"CHG":21.4546,"PCHG":218.22914,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-04 23:39:55","ADY":1033,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-337","SUBJID":"id-337","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.22759,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-03","TRTSDTM":"2020-06-05 23:39:55","TRTEDTM":"2023-06-06 17:39:55","TRT01SDTM":"2020-06-05 23:39:55","TRT01EDTM":"2022-06-06 11:39:55","TRT02SDTM":"2022-06-06 11:39:55","TRT02EDTM":"2023-06-06 17:39:55","AP01SDTM":"2020-06-05 23:39:55","AP01EDTM":"2022-06-06 11:39:55","AP02SDTM":"2022-06-06 11:39:55","AP02EDTM":"2023-06-06 17:39:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-06","EOSDY":1096,"LSTALVDT":"2023-07-03","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8108,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.07331,"AVALU":"mg/L","BASE2":9.07331,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-17 23:39:55","ADY":104,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-337","SUBJID":"id-337","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.22759,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-03","TRTSDTM":"2020-06-05 23:39:55","TRTEDTM":"2023-06-06 17:39:55","TRT01SDTM":"2020-06-05 23:39:55","TRT01EDTM":"2022-06-06 11:39:55","TRT02SDTM":"2022-06-06 11:39:55","TRT02EDTM":"2023-06-06 17:39:55","AP01SDTM":"2020-06-05 23:39:55","AP01EDTM":"2022-06-06 11:39:55","AP02SDTM":"2022-06-06 11:39:55","AP02EDTM":"2023-06-06 17:39:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-06","EOSDY":1096,"LSTALVDT":"2023-07-03","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7599,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.62532,"AVALU":"mg/L","BASE2":9.07331,"BASE":9.62532,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.55201,"PCHG2":6.08392,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-26 23:39:55","ADY":235,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-337","SUBJID":"id-337","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.22759,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-03","TRTSDTM":"2020-06-05 23:39:55","TRTEDTM":"2023-06-06 17:39:55","TRT01SDTM":"2020-06-05 23:39:55","TRT01EDTM":"2022-06-06 11:39:55","TRT02SDTM":"2022-06-06 11:39:55","TRT02EDTM":"2023-06-06 17:39:55","AP01SDTM":"2020-06-05 23:39:55","AP01EDTM":"2022-06-06 11:39:55","AP02SDTM":"2022-06-06 11:39:55","AP02EDTM":"2023-06-06 17:39:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-06","EOSDY":1096,"LSTALVDT":"2023-07-03","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":167,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.52759,"AVALU":"mg/L","BASE2":9.07331,"BASE":9.62532,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.54572,"PCHG2":-6.01452,"CHG":-1.09773,"PCHG":-11.40459,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-11 23:39:55","ADY":251,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-337","SUBJID":"id-337","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.22759,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-03","TRTSDTM":"2020-06-05 23:39:55","TRTEDTM":"2023-06-06 17:39:55","TRT01SDTM":"2020-06-05 23:39:55","TRT01EDTM":"2022-06-06 11:39:55","TRT02SDTM":"2022-06-06 11:39:55","TRT02EDTM":"2023-06-06 17:39:55","AP01SDTM":"2020-06-05 23:39:55","AP01EDTM":"2022-06-06 11:39:55","AP02SDTM":"2022-06-06 11:39:55","AP02EDTM":"2023-06-06 17:39:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-06","EOSDY":1096,"LSTALVDT":"2023-07-03","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3173,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.58369,"AVALU":"mg/L","BASE2":9.07331,"BASE":9.62532,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.51038,"PCHG2":5.62506,"CHG":-0.04163,"PCHG":-0.43254,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-13 23:39:55","ADY":556,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-337","SUBJID":"id-337","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.22759,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-03","TRTSDTM":"2020-06-05 23:39:55","TRTEDTM":"2023-06-06 17:39:55","TRT01SDTM":"2020-06-05 23:39:55","TRT01EDTM":"2022-06-06 11:39:55","TRT02SDTM":"2022-06-06 11:39:55","TRT02EDTM":"2023-06-06 17:39:55","AP01SDTM":"2020-06-05 23:39:55","AP01EDTM":"2022-06-06 11:39:55","AP02SDTM":"2022-06-06 11:39:55","AP02EDTM":"2023-06-06 17:39:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-06","EOSDY":1096,"LSTALVDT":"2023-07-03","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":271,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.14507,"AVALU":"mg/L","BASE2":9.07331,"BASE":9.62532,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07177,"PCHG2":0.79095,"CHG":-0.48025,"PCHG":-4.98942,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-16 23:39:55","ADY":802,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-337","SUBJID":"id-337","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.22759,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-03","TRTSDTM":"2020-06-05 23:39:55","TRTEDTM":"2023-06-06 17:39:55","TRT01SDTM":"2020-06-05 23:39:55","TRT01EDTM":"2022-06-06 11:39:55","TRT02SDTM":"2022-06-06 11:39:55","TRT02EDTM":"2023-06-06 17:39:55","AP01SDTM":"2020-06-05 23:39:55","AP01EDTM":"2022-06-06 11:39:55","AP02SDTM":"2022-06-06 11:39:55","AP02EDTM":"2023-06-06 17:39:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-06","EOSDY":1096,"LSTALVDT":"2023-07-03","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7231,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.61822,"AVALU":"mg/L","BASE2":9.07331,"BASE":9.62532,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.54491,"PCHG2":6.00565,"CHG":-0.0071,"PCHG":-0.07378,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-29 23:39:55","ADY":907,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-337","SUBJID":"id-337","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.22759,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-03","TRTSDTM":"2020-06-05 23:39:55","TRTEDTM":"2023-06-06 17:39:55","TRT01SDTM":"2020-06-05 23:39:55","TRT01EDTM":"2022-06-06 11:39:55","TRT02SDTM":"2022-06-06 11:39:55","TRT02EDTM":"2023-06-06 17:39:55","AP01SDTM":"2020-06-05 23:39:55","AP01EDTM":"2022-06-06 11:39:55","AP02SDTM":"2022-06-06 11:39:55","AP02EDTM":"2023-06-06 17:39:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-06","EOSDY":1096,"LSTALVDT":"2023-07-03","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3829,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.60884,"AVALU":"mg/L","BASE2":9.07331,"BASE":9.62532,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.46446,"PCHG2":-16.14036,"CHG":-2.01648,"PCHG":-20.94972,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2023-04-04 23:39:55","ADY":1033,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-337","SUBJID":"id-337","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.22759,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-03","TRTSDTM":"2020-06-05 23:39:55","TRTEDTM":"2023-06-06 17:39:55","TRT01SDTM":"2020-06-05 23:39:55","TRT01EDTM":"2022-06-06 11:39:55","TRT02SDTM":"2022-06-06 11:39:55","TRT02EDTM":"2023-06-06 17:39:55","AP01SDTM":"2020-06-05 23:39:55","AP01EDTM":"2022-06-06 11:39:55","AP02SDTM":"2022-06-06 11:39:55","AP02EDTM":"2023-06-06 17:39:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-06","EOSDY":1096,"LSTALVDT":"2023-07-03","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3776,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04844,"AVALU":"g/L","BASE2":3.04844,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"2","ADTM":"2020-09-17 23:39:55","ADY":104,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-337","SUBJID":"id-337","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.22759,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-03","TRTSDTM":"2020-06-05 23:39:55","TRTEDTM":"2023-06-06 17:39:55","TRT01SDTM":"2020-06-05 23:39:55","TRT01EDTM":"2022-06-06 11:39:55","TRT02SDTM":"2022-06-06 11:39:55","TRT02EDTM":"2023-06-06 17:39:55","AP01SDTM":"2020-06-05 23:39:55","AP01EDTM":"2022-06-06 11:39:55","AP02SDTM":"2022-06-06 11:39:55","AP02EDTM":"2023-06-06 17:39:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-06","EOSDY":1096,"LSTALVDT":"2023-07-03","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3374,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01347,"AVALU":"g/L","BASE2":3.04844,"BASE":3.01347,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.03498,"PCHG2":-1.14735,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2021-01-26 23:39:55","ADY":235,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-337","SUBJID":"id-337","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.22759,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-03","TRTSDTM":"2020-06-05 23:39:55","TRTEDTM":"2023-06-06 17:39:55","TRT01SDTM":"2020-06-05 23:39:55","TRT01EDTM":"2022-06-06 11:39:55","TRT02SDTM":"2022-06-06 11:39:55","TRT02EDTM":"2023-06-06 17:39:55","AP01SDTM":"2020-06-05 23:39:55","AP01EDTM":"2022-06-06 11:39:55","AP02SDTM":"2022-06-06 11:39:55","AP02EDTM":"2023-06-06 17:39:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-06","EOSDY":1096,"LSTALVDT":"2023-07-03","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4199,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84148,"AVALU":"g/L","BASE2":3.04844,"BASE":3.01347,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20697,"PCHG2":-6.78923,"CHG":-0.17199,"PCHG":-5.70736,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-02-11 23:39:55","ADY":251,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-337","SUBJID":"id-337","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.22759,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-03","TRTSDTM":"2020-06-05 23:39:55","TRTEDTM":"2023-06-06 17:39:55","TRT01SDTM":"2020-06-05 23:39:55","TRT01EDTM":"2022-06-06 11:39:55","TRT02SDTM":"2022-06-06 11:39:55","TRT02EDTM":"2023-06-06 17:39:55","AP01SDTM":"2020-06-05 23:39:55","AP01EDTM":"2022-06-06 11:39:55","AP02SDTM":"2022-06-06 11:39:55","AP02EDTM":"2023-06-06 17:39:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-06","EOSDY":1096,"LSTALVDT":"2023-07-03","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6178,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02196,"AVALU":"g/L","BASE2":3.04844,"BASE":3.01347,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02649,"PCHG2":-0.86883,"CHG":0.00849,"PCHG":0.28175,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"4","BTOXGR":"2","ADTM":"2021-12-13 23:39:55","ADY":556,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-337","SUBJID":"id-337","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.22759,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-03","TRTSDTM":"2020-06-05 23:39:55","TRTEDTM":"2023-06-06 17:39:55","TRT01SDTM":"2020-06-05 23:39:55","TRT01EDTM":"2022-06-06 11:39:55","TRT02SDTM":"2022-06-06 11:39:55","TRT02EDTM":"2023-06-06 17:39:55","AP01SDTM":"2020-06-05 23:39:55","AP01EDTM":"2022-06-06 11:39:55","AP02SDTM":"2022-06-06 11:39:55","AP02EDTM":"2023-06-06 17:39:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-06","EOSDY":1096,"LSTALVDT":"2023-07-03","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1940,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91548,"AVALU":"g/L","BASE2":3.04844,"BASE":3.01347,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13296,"PCHG2":-4.36153,"CHG":-0.09798,"PCHG":-3.25148,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-08-16 23:39:55","ADY":802,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-337","SUBJID":"id-337","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.22759,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-03","TRTSDTM":"2020-06-05 23:39:55","TRTEDTM":"2023-06-06 17:39:55","TRT01SDTM":"2020-06-05 23:39:55","TRT01EDTM":"2022-06-06 11:39:55","TRT02SDTM":"2022-06-06 11:39:55","TRT02EDTM":"2023-06-06 17:39:55","AP01SDTM":"2020-06-05 23:39:55","AP01EDTM":"2022-06-06 11:39:55","AP02SDTM":"2022-06-06 11:39:55","AP02EDTM":"2023-06-06 17:39:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-06","EOSDY":1096,"LSTALVDT":"2023-07-03","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2163,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94781,"AVALU":"g/L","BASE2":3.04844,"BASE":3.01347,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10064,"PCHG2":-3.3013,"CHG":-0.06566,"PCHG":-2.17894,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-11-29 23:39:55","ADY":907,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-337","SUBJID":"id-337","SITEID":"CHN-1","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.22759,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-03","TRTSDTM":"2020-06-05 23:39:55","TRTEDTM":"2023-06-06 17:39:55","TRT01SDTM":"2020-06-05 23:39:55","TRT01EDTM":"2022-06-06 11:39:55","TRT02SDTM":"2022-06-06 11:39:55","TRT02EDTM":"2023-06-06 17:39:55","AP01SDTM":"2020-06-05 23:39:55","AP01EDTM":"2022-06-06 11:39:55","AP02SDTM":"2022-06-06 11:39:55","AP02EDTM":"2023-06-06 17:39:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-06","EOSDY":1096,"LSTALVDT":"2023-07-03","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6406,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93639,"AVALU":"g/L","BASE2":3.04844,"BASE":3.01347,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11205,"PCHG2":-3.67561,"CHG":-0.07707,"PCHG":-2.5576,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2023-04-04 23:39:55","ADY":1033,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-344","SUBJID":"id-344","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.58443,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-16 18:51:26","TRTEDTM":"2023-11-17 12:51:26","TRT01SDTM":"2020-11-16 18:51:26","TRT01EDTM":"2022-11-17 06:51:26","TRT02SDTM":"2022-11-17 06:51:26","TRT02EDTM":"2023-11-17 12:51:26","AP01SDTM":"2020-11-16 18:51:26","AP01EDTM":"2022-11-17 06:51:26","AP02SDTM":"2022-11-17 06:51:26","AP02EDTM":"2023-11-17 12:51:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-17","EOSDY":1096,"LSTALVDT":"2023-12-09","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7353,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.03283,"AVALU":"U/L","BASE2":26.03283,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-08 18:51:26","ADY":22,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-344","SUBJID":"id-344","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.58443,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-16 18:51:26","TRTEDTM":"2023-11-17 12:51:26","TRT01SDTM":"2020-11-16 18:51:26","TRT01EDTM":"2022-11-17 06:51:26","TRT02SDTM":"2022-11-17 06:51:26","TRT02EDTM":"2023-11-17 12:51:26","AP01SDTM":"2020-11-16 18:51:26","AP01EDTM":"2022-11-17 06:51:26","AP02SDTM":"2022-11-17 06:51:26","AP02EDTM":"2023-11-17 12:51:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-17","EOSDY":1096,"LSTALVDT":"2023-12-09","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":399,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.30807,"AVALU":"U/L","BASE2":26.03283,"BASE":24.30807,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.72476,"PCHG2":-6.62532,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-28 18:51:26","ADY":285,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-344","SUBJID":"id-344","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.58443,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-16 18:51:26","TRTEDTM":"2023-11-17 12:51:26","TRT01SDTM":"2020-11-16 18:51:26","TRT01EDTM":"2022-11-17 06:51:26","TRT02SDTM":"2022-11-17 06:51:26","TRT02EDTM":"2023-11-17 12:51:26","AP01SDTM":"2020-11-16 18:51:26","AP01EDTM":"2022-11-17 06:51:26","AP02SDTM":"2022-11-17 06:51:26","AP02EDTM":"2023-11-17 12:51:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-17","EOSDY":1096,"LSTALVDT":"2023-12-09","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2692,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.43214,"AVALU":"U/L","BASE2":26.03283,"BASE":24.30807,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.6007,"PCHG2":-44.56179,"CHG":-9.87594,"PCHG":-40.62822,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-19 18:51:26","ADY":429,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-344","SUBJID":"id-344","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.58443,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-16 18:51:26","TRTEDTM":"2023-11-17 12:51:26","TRT01SDTM":"2020-11-16 18:51:26","TRT01EDTM":"2022-11-17 06:51:26","TRT02SDTM":"2022-11-17 06:51:26","TRT02EDTM":"2023-11-17 12:51:26","AP01SDTM":"2020-11-16 18:51:26","AP01EDTM":"2022-11-17 06:51:26","AP02SDTM":"2022-11-17 06:51:26","AP02EDTM":"2023-11-17 12:51:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-17","EOSDY":1096,"LSTALVDT":"2023-12-09","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6258,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.58529,"AVALU":"U/L","BASE2":26.03283,"BASE":24.30807,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.44755,"PCHG2":-9.40177,"CHG":-0.72279,"PCHG":-2.97345,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-02 18:51:26","ADY":746,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-344","SUBJID":"id-344","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.58443,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-16 18:51:26","TRTEDTM":"2023-11-17 12:51:26","TRT01SDTM":"2020-11-16 18:51:26","TRT01EDTM":"2022-11-17 06:51:26","TRT02SDTM":"2022-11-17 06:51:26","TRT02EDTM":"2023-11-17 12:51:26","AP01SDTM":"2020-11-16 18:51:26","AP01EDTM":"2022-11-17 06:51:26","AP02SDTM":"2022-11-17 06:51:26","AP02EDTM":"2023-11-17 12:51:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-17","EOSDY":1096,"LSTALVDT":"2023-12-09","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":72,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.50875,"AVALU":"U/L","BASE2":26.03283,"BASE":24.30807,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-19.52409,"PCHG2":-74.99794,"CHG":-17.79933,"PCHG":-73.22394,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2023-06-03 18:51:26","ADY":929,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-344","SUBJID":"id-344","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.58443,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-16 18:51:26","TRTEDTM":"2023-11-17 12:51:26","TRT01SDTM":"2020-11-16 18:51:26","TRT01EDTM":"2022-11-17 06:51:26","TRT02SDTM":"2022-11-17 06:51:26","TRT02EDTM":"2023-11-17 12:51:26","AP01SDTM":"2020-11-16 18:51:26","AP01EDTM":"2022-11-17 06:51:26","AP02SDTM":"2022-11-17 06:51:26","AP02EDTM":"2023-11-17 12:51:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-17","EOSDY":1096,"LSTALVDT":"2023-12-09","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4176,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.11432,"AVALU":"U/L","BASE2":26.03283,"BASE":24.30807,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.91851,"PCHG2":-22.73481,"CHG":-4.19376,"PCHG":-17.25252,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-25 18:51:26","ADY":981,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-344","SUBJID":"id-344","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.58443,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-16 18:51:26","TRTEDTM":"2023-11-17 12:51:26","TRT01SDTM":"2020-11-16 18:51:26","TRT01EDTM":"2022-11-17 06:51:26","TRT02SDTM":"2022-11-17 06:51:26","TRT02EDTM":"2023-11-17 12:51:26","AP01SDTM":"2020-11-16 18:51:26","AP01EDTM":"2022-11-17 06:51:26","AP02SDTM":"2022-11-17 06:51:26","AP02EDTM":"2023-11-17 12:51:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-17","EOSDY":1096,"LSTALVDT":"2023-12-09","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1909,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.85955,"AVALU":"U/L","BASE2":26.03283,"BASE":24.30807,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.82672,"PCHG2":22.38219,"CHG":7.55148,"PCHG":31.06571,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-20 18:51:26","ADY":1038,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-344","SUBJID":"id-344","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.58443,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-16 18:51:26","TRTEDTM":"2023-11-17 12:51:26","TRT01SDTM":"2020-11-16 18:51:26","TRT01EDTM":"2022-11-17 06:51:26","TRT02SDTM":"2022-11-17 06:51:26","TRT02EDTM":"2023-11-17 12:51:26","AP01SDTM":"2020-11-16 18:51:26","AP01EDTM":"2022-11-17 06:51:26","AP02SDTM":"2022-11-17 06:51:26","AP02EDTM":"2023-11-17 12:51:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-17","EOSDY":1096,"LSTALVDT":"2023-12-09","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8301,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.58998,"AVALU":"mg/L","BASE2":9.58998,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-08 18:51:26","ADY":22,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-344","SUBJID":"id-344","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.58443,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-16 18:51:26","TRTEDTM":"2023-11-17 12:51:26","TRT01SDTM":"2020-11-16 18:51:26","TRT01EDTM":"2022-11-17 06:51:26","TRT02SDTM":"2022-11-17 06:51:26","TRT02EDTM":"2023-11-17 12:51:26","AP01SDTM":"2020-11-16 18:51:26","AP01EDTM":"2022-11-17 06:51:26","AP02SDTM":"2022-11-17 06:51:26","AP02EDTM":"2023-11-17 12:51:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-17","EOSDY":1096,"LSTALVDT":"2023-12-09","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2236,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.35991,"AVALU":"mg/L","BASE2":9.58998,"BASE":9.35991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.23007,"PCHG2":-2.39908,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-28 18:51:26","ADY":285,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-344","SUBJID":"id-344","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.58443,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-16 18:51:26","TRTEDTM":"2023-11-17 12:51:26","TRT01SDTM":"2020-11-16 18:51:26","TRT01EDTM":"2022-11-17 06:51:26","TRT02SDTM":"2022-11-17 06:51:26","TRT02EDTM":"2023-11-17 12:51:26","AP01SDTM":"2020-11-16 18:51:26","AP01EDTM":"2022-11-17 06:51:26","AP02SDTM":"2022-11-17 06:51:26","AP02EDTM":"2023-11-17 12:51:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-17","EOSDY":1096,"LSTALVDT":"2023-12-09","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":691,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.20982,"AVALU":"mg/L","BASE2":9.58998,"BASE":9.35991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.38016,"PCHG2":-3.96418,"CHG":-0.15009,"PCHG":-1.60357,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-19 18:51:26","ADY":429,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-344","SUBJID":"id-344","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.58443,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-16 18:51:26","TRTEDTM":"2023-11-17 12:51:26","TRT01SDTM":"2020-11-16 18:51:26","TRT01EDTM":"2022-11-17 06:51:26","TRT02SDTM":"2022-11-17 06:51:26","TRT02EDTM":"2023-11-17 12:51:26","AP01SDTM":"2020-11-16 18:51:26","AP01EDTM":"2022-11-17 06:51:26","AP02SDTM":"2022-11-17 06:51:26","AP02EDTM":"2023-11-17 12:51:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-17","EOSDY":1096,"LSTALVDT":"2023-12-09","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5924,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.29751,"AVALU":"mg/L","BASE2":9.58998,"BASE":9.35991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.29247,"PCHG2":-13.4773,"CHG":-1.0624,"PCHG":-11.35053,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-02 18:51:26","ADY":746,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-344","SUBJID":"id-344","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.58443,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-16 18:51:26","TRTEDTM":"2023-11-17 12:51:26","TRT01SDTM":"2020-11-16 18:51:26","TRT01EDTM":"2022-11-17 06:51:26","TRT02SDTM":"2022-11-17 06:51:26","TRT02EDTM":"2023-11-17 12:51:26","AP01SDTM":"2020-11-16 18:51:26","AP01EDTM":"2022-11-17 06:51:26","AP02SDTM":"2022-11-17 06:51:26","AP02EDTM":"2023-11-17 12:51:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-17","EOSDY":1096,"LSTALVDT":"2023-12-09","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1072,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.66815,"AVALU":"mg/L","BASE2":9.58998,"BASE":9.35991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.92184,"PCHG2":-9.61249,"CHG":-0.69176,"PCHG":-7.39072,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-03 18:51:26","ADY":929,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-344","SUBJID":"id-344","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.58443,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-16 18:51:26","TRTEDTM":"2023-11-17 12:51:26","TRT01SDTM":"2020-11-16 18:51:26","TRT01EDTM":"2022-11-17 06:51:26","TRT02SDTM":"2022-11-17 06:51:26","TRT02EDTM":"2023-11-17 12:51:26","AP01SDTM":"2020-11-16 18:51:26","AP01EDTM":"2022-11-17 06:51:26","AP02SDTM":"2022-11-17 06:51:26","AP02EDTM":"2023-11-17 12:51:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-17","EOSDY":1096,"LSTALVDT":"2023-12-09","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8221,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.94524,"AVALU":"mg/L","BASE2":9.58998,"BASE":9.35991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.64474,"PCHG2":-6.72307,"CHG":-0.41467,"PCHG":-4.43028,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-25 18:51:26","ADY":981,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-344","SUBJID":"id-344","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.58443,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-16 18:51:26","TRTEDTM":"2023-11-17 12:51:26","TRT01SDTM":"2020-11-16 18:51:26","TRT01EDTM":"2022-11-17 06:51:26","TRT02SDTM":"2022-11-17 06:51:26","TRT02EDTM":"2023-11-17 12:51:26","AP01SDTM":"2020-11-16 18:51:26","AP01EDTM":"2022-11-17 06:51:26","AP02SDTM":"2022-11-17 06:51:26","AP02EDTM":"2023-11-17 12:51:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-17","EOSDY":1096,"LSTALVDT":"2023-12-09","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6048,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.1476,"AVALU":"mg/L","BASE2":9.58998,"BASE":9.35991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.44239,"PCHG2":-4.61302,"CHG":-0.21232,"PCHG":-2.26836,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-20 18:51:26","ADY":1038,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-344","SUBJID":"id-344","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.58443,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-16 18:51:26","TRTEDTM":"2023-11-17 12:51:26","TRT01SDTM":"2020-11-16 18:51:26","TRT01EDTM":"2022-11-17 06:51:26","TRT02SDTM":"2022-11-17 06:51:26","TRT02EDTM":"2023-11-17 12:51:26","AP01SDTM":"2020-11-16 18:51:26","AP01EDTM":"2022-11-17 06:51:26","AP02SDTM":"2022-11-17 06:51:26","AP02EDTM":"2023-11-17 12:51:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-17","EOSDY":1096,"LSTALVDT":"2023-12-09","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7465,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96782,"AVALU":"g/L","BASE2":2.96782,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-12-08 18:51:26","ADY":22,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-344","SUBJID":"id-344","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.58443,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-16 18:51:26","TRTEDTM":"2023-11-17 12:51:26","TRT01SDTM":"2020-11-16 18:51:26","TRT01EDTM":"2022-11-17 06:51:26","TRT02SDTM":"2022-11-17 06:51:26","TRT02EDTM":"2023-11-17 12:51:26","AP01SDTM":"2020-11-16 18:51:26","AP01EDTM":"2022-11-17 06:51:26","AP02SDTM":"2022-11-17 06:51:26","AP02EDTM":"2023-11-17 12:51:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-17","EOSDY":1096,"LSTALVDT":"2023-12-09","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2483,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.06558,"AVALU":"g/L","BASE2":2.96782,"BASE":3.06558,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.09776,"PCHG2":3.29394,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2021-08-28 18:51:26","ADY":285,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-344","SUBJID":"id-344","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.58443,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-16 18:51:26","TRTEDTM":"2023-11-17 12:51:26","TRT01SDTM":"2020-11-16 18:51:26","TRT01EDTM":"2022-11-17 06:51:26","TRT02SDTM":"2022-11-17 06:51:26","TRT02EDTM":"2023-11-17 12:51:26","AP01SDTM":"2020-11-16 18:51:26","AP01EDTM":"2022-11-17 06:51:26","AP02SDTM":"2022-11-17 06:51:26","AP02EDTM":"2023-11-17 12:51:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-17","EOSDY":1096,"LSTALVDT":"2023-12-09","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5104,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82713,"AVALU":"g/L","BASE2":2.96782,"BASE":3.06558,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1407,"PCHG2":-4.74069,"CHG":-0.23845,"PCHG":-7.77841,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-01-19 18:51:26","ADY":429,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-344","SUBJID":"id-344","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.58443,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-16 18:51:26","TRTEDTM":"2023-11-17 12:51:26","TRT01SDTM":"2020-11-16 18:51:26","TRT01EDTM":"2022-11-17 06:51:26","TRT02SDTM":"2022-11-17 06:51:26","TRT02EDTM":"2023-11-17 12:51:26","AP01SDTM":"2020-11-16 18:51:26","AP01EDTM":"2022-11-17 06:51:26","AP02SDTM":"2022-11-17 06:51:26","AP02EDTM":"2023-11-17 12:51:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-17","EOSDY":1096,"LSTALVDT":"2023-12-09","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7551,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87488,"AVALU":"g/L","BASE2":2.96782,"BASE":3.06558,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09295,"PCHG2":-3.13188,"CHG":-0.19071,"PCHG":-6.22091,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-12-02 18:51:26","ADY":746,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-344","SUBJID":"id-344","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.58443,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-16 18:51:26","TRTEDTM":"2023-11-17 12:51:26","TRT01SDTM":"2020-11-16 18:51:26","TRT01EDTM":"2022-11-17 06:51:26","TRT02SDTM":"2022-11-17 06:51:26","TRT02EDTM":"2023-11-17 12:51:26","AP01SDTM":"2020-11-16 18:51:26","AP01EDTM":"2022-11-17 06:51:26","AP02SDTM":"2022-11-17 06:51:26","AP02EDTM":"2023-11-17 12:51:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-17","EOSDY":1096,"LSTALVDT":"2023-12-09","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7945,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89361,"AVALU":"g/L","BASE2":2.96782,"BASE":3.06558,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07421,"PCHG2":-2.50062,"CHG":-0.17197,"PCHG":-5.60978,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2023-06-03 18:51:26","ADY":929,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-344","SUBJID":"id-344","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.58443,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-16 18:51:26","TRTEDTM":"2023-11-17 12:51:26","TRT01SDTM":"2020-11-16 18:51:26","TRT01EDTM":"2022-11-17 06:51:26","TRT02SDTM":"2022-11-17 06:51:26","TRT02EDTM":"2023-11-17 12:51:26","AP01SDTM":"2020-11-16 18:51:26","AP01EDTM":"2022-11-17 06:51:26","AP02SDTM":"2022-11-17 06:51:26","AP02EDTM":"2023-11-17 12:51:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-17","EOSDY":1096,"LSTALVDT":"2023-12-09","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":80,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82664,"AVALU":"g/L","BASE2":2.96782,"BASE":3.06558,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14119,"PCHG2":-4.75719,"CHG":-0.23894,"PCHG":-7.79439,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2023-07-25 18:51:26","ADY":981,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-344","SUBJID":"id-344","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.58443,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-16 18:51:26","TRTEDTM":"2023-11-17 12:51:26","TRT01SDTM":"2020-11-16 18:51:26","TRT01EDTM":"2022-11-17 06:51:26","TRT02SDTM":"2022-11-17 06:51:26","TRT02EDTM":"2023-11-17 12:51:26","AP01SDTM":"2020-11-16 18:51:26","AP01EDTM":"2022-11-17 06:51:26","AP02SDTM":"2022-11-17 06:51:26","AP02EDTM":"2023-11-17 12:51:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-17","EOSDY":1096,"LSTALVDT":"2023-12-09","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4336,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.73668,"AVALU":"g/L","BASE2":2.96782,"BASE":3.06558,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.23114,"PCHG2":-7.78824,"CHG":-0.3289,"PCHG":-10.72878,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2023-09-20 18:51:26","ADY":1038,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-346","SUBJID":"id-346","SITEID":"CHN-1","AGE":21,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08004,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-20","TRTSDTM":"2019-11-23 18:34:29","TRTEDTM":"2022-02-12 16:44:55","TRT01SDTM":"2019-11-23 18:34:29","TRT01EDTM":"2021-02-12 10:44:55","TRT02SDTM":"2021-02-12 10:44:55","TRT02EDTM":"2022-02-12 16:44:55","AP01SDTM":"2019-11-23 18:34:29","AP01EDTM":"2021-02-12 10:44:55","AP02SDTM":"2021-02-12 10:44:55","AP02EDTM":"2022-02-12 16:44:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":812,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":834,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":293,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":38.87167,"AVALU":"U/L","BASE2":38.87167,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2019-12-11 18:34:29","ADY":18,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-346","SUBJID":"id-346","SITEID":"CHN-1","AGE":21,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08004,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-20","TRTSDTM":"2019-11-23 18:34:29","TRTEDTM":"2022-02-12 16:44:55","TRT01SDTM":"2019-11-23 18:34:29","TRT01EDTM":"2021-02-12 10:44:55","TRT02SDTM":"2021-02-12 10:44:55","TRT02EDTM":"2022-02-12 16:44:55","AP01SDTM":"2019-11-23 18:34:29","AP01EDTM":"2021-02-12 10:44:55","AP02SDTM":"2021-02-12 10:44:55","AP02EDTM":"2022-02-12 16:44:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":812,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":834,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3861,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.86663,"AVALU":"U/L","BASE2":38.87167,"BASE":6.86663,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-32.00504,"PCHG2":-82.33514,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2019-12-14 18:34:29","ADY":21,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-346","SUBJID":"id-346","SITEID":"CHN-1","AGE":21,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08004,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-20","TRTSDTM":"2019-11-23 18:34:29","TRTEDTM":"2022-02-12 16:44:55","TRT01SDTM":"2019-11-23 18:34:29","TRT01EDTM":"2021-02-12 10:44:55","TRT02SDTM":"2021-02-12 10:44:55","TRT02EDTM":"2022-02-12 16:44:55","AP01SDTM":"2019-11-23 18:34:29","AP01EDTM":"2021-02-12 10:44:55","AP02SDTM":"2021-02-12 10:44:55","AP02EDTM":"2022-02-12 16:44:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":812,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":834,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5017,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.9703,"AVALU":"U/L","BASE2":38.87167,"BASE":6.86663,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-20.90137,"PCHG2":-53.77019,"CHG":11.10367,"PCHG":161.70494,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-04-06 18:34:29","ADY":135,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-346","SUBJID":"id-346","SITEID":"CHN-1","AGE":21,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08004,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-20","TRTSDTM":"2019-11-23 18:34:29","TRTEDTM":"2022-02-12 16:44:55","TRT01SDTM":"2019-11-23 18:34:29","TRT01EDTM":"2021-02-12 10:44:55","TRT02SDTM":"2021-02-12 10:44:55","TRT02EDTM":"2022-02-12 16:44:55","AP01SDTM":"2019-11-23 18:34:29","AP01EDTM":"2021-02-12 10:44:55","AP02SDTM":"2021-02-12 10:44:55","AP02EDTM":"2022-02-12 16:44:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":812,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":834,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7090,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.85691,"AVALU":"U/L","BASE2":38.87167,"BASE":6.86663,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-24.01476,"PCHG2":-61.77959,"CHG":7.99028,"PCHG":116.36407,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-04-27 18:34:29","ADY":156,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-346","SUBJID":"id-346","SITEID":"CHN-1","AGE":21,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08004,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-20","TRTSDTM":"2019-11-23 18:34:29","TRTEDTM":"2022-02-12 16:44:55","TRT01SDTM":"2019-11-23 18:34:29","TRT01EDTM":"2021-02-12 10:44:55","TRT02SDTM":"2021-02-12 10:44:55","TRT02EDTM":"2022-02-12 16:44:55","AP01SDTM":"2019-11-23 18:34:29","AP01EDTM":"2021-02-12 10:44:55","AP02SDTM":"2021-02-12 10:44:55","AP02EDTM":"2022-02-12 16:44:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":812,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":834,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5542,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.91343,"AVALU":"U/L","BASE2":38.87167,"BASE":6.86663,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-25.95824,"PCHG2":-66.77932,"CHG":6.0468,"PCHG":88.06079,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-05-11 18:34:29","ADY":170,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-346","SUBJID":"id-346","SITEID":"CHN-1","AGE":21,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08004,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-20","TRTSDTM":"2019-11-23 18:34:29","TRTEDTM":"2022-02-12 16:44:55","TRT01SDTM":"2019-11-23 18:34:29","TRT01EDTM":"2021-02-12 10:44:55","TRT02SDTM":"2021-02-12 10:44:55","TRT02EDTM":"2022-02-12 16:44:55","AP01SDTM":"2019-11-23 18:34:29","AP01EDTM":"2021-02-12 10:44:55","AP02SDTM":"2021-02-12 10:44:55","AP02EDTM":"2022-02-12 16:44:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":812,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":834,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8319,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.6356,"AVALU":"U/L","BASE2":38.87167,"BASE":6.86663,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-38.23606,"PCHG2":-98.36487,"CHG":-6.23102,"PCHG":-90.74362,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-2","ADTM":"2020-09-18 18:34:29","ADY":300,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-346","SUBJID":"id-346","SITEID":"CHN-1","AGE":21,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08004,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-20","TRTSDTM":"2019-11-23 18:34:29","TRTEDTM":"2022-02-12 16:44:55","TRT01SDTM":"2019-11-23 18:34:29","TRT01EDTM":"2021-02-12 10:44:55","TRT02SDTM":"2021-02-12 10:44:55","TRT02EDTM":"2022-02-12 16:44:55","AP01SDTM":"2019-11-23 18:34:29","AP01EDTM":"2021-02-12 10:44:55","AP02SDTM":"2021-02-12 10:44:55","AP02EDTM":"2022-02-12 16:44:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":812,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":834,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3947,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.48197,"AVALU":"U/L","BASE2":38.87167,"BASE":6.86663,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-24.3897,"PCHG2":-62.74415,"CHG":7.61534,"PCHG":110.90372,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-11-13 18:34:29","ADY":721,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-346","SUBJID":"id-346","SITEID":"CHN-1","AGE":21,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08004,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-20","TRTSDTM":"2019-11-23 18:34:29","TRTEDTM":"2022-02-12 16:44:55","TRT01SDTM":"2019-11-23 18:34:29","TRT01EDTM":"2021-02-12 10:44:55","TRT02SDTM":"2021-02-12 10:44:55","TRT02EDTM":"2022-02-12 16:44:55","AP01SDTM":"2019-11-23 18:34:29","AP01EDTM":"2021-02-12 10:44:55","AP02SDTM":"2021-02-12 10:44:55","AP02EDTM":"2022-02-12 16:44:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":812,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":834,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3888,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.48339,"AVALU":"mg/L","BASE2":8.48339,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-11 18:34:29","ADY":18,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-346","SUBJID":"id-346","SITEID":"CHN-1","AGE":21,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08004,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-20","TRTSDTM":"2019-11-23 18:34:29","TRTEDTM":"2022-02-12 16:44:55","TRT01SDTM":"2019-11-23 18:34:29","TRT01EDTM":"2021-02-12 10:44:55","TRT02SDTM":"2021-02-12 10:44:55","TRT02EDTM":"2022-02-12 16:44:55","AP01SDTM":"2019-11-23 18:34:29","AP01EDTM":"2021-02-12 10:44:55","AP02SDTM":"2021-02-12 10:44:55","AP02EDTM":"2022-02-12 16:44:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":812,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":834,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":583,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.60691,"AVALU":"mg/L","BASE2":8.48339,"BASE":9.60691,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.12352,"PCHG2":13.24377,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-14 18:34:29","ADY":21,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-346","SUBJID":"id-346","SITEID":"CHN-1","AGE":21,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08004,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-20","TRTSDTM":"2019-11-23 18:34:29","TRTEDTM":"2022-02-12 16:44:55","TRT01SDTM":"2019-11-23 18:34:29","TRT01EDTM":"2021-02-12 10:44:55","TRT02SDTM":"2021-02-12 10:44:55","TRT02EDTM":"2022-02-12 16:44:55","AP01SDTM":"2019-11-23 18:34:29","AP01EDTM":"2021-02-12 10:44:55","AP02SDTM":"2021-02-12 10:44:55","AP02EDTM":"2022-02-12 16:44:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":812,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":834,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1200,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.76879,"AVALU":"mg/L","BASE2":8.48339,"BASE":9.60691,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.2854,"PCHG2":3.36418,"CHG":-0.83812,"PCHG":-8.72418,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-06 18:34:29","ADY":135,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-346","SUBJID":"id-346","SITEID":"CHN-1","AGE":21,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08004,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-20","TRTSDTM":"2019-11-23 18:34:29","TRTEDTM":"2022-02-12 16:44:55","TRT01SDTM":"2019-11-23 18:34:29","TRT01EDTM":"2021-02-12 10:44:55","TRT02SDTM":"2021-02-12 10:44:55","TRT02EDTM":"2022-02-12 16:44:55","AP01SDTM":"2019-11-23 18:34:29","AP01EDTM":"2021-02-12 10:44:55","AP02SDTM":"2021-02-12 10:44:55","AP02EDTM":"2022-02-12 16:44:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":812,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":834,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7869,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.53505,"AVALU":"mg/L","BASE2":8.48339,"BASE":9.60691,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05167,"PCHG2":0.60901,"CHG":-1.07186,"PCHG":-11.15713,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-27 18:34:29","ADY":156,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-346","SUBJID":"id-346","SITEID":"CHN-1","AGE":21,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08004,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-20","TRTSDTM":"2019-11-23 18:34:29","TRTEDTM":"2022-02-12 16:44:55","TRT01SDTM":"2019-11-23 18:34:29","TRT01EDTM":"2021-02-12 10:44:55","TRT02SDTM":"2021-02-12 10:44:55","TRT02EDTM":"2022-02-12 16:44:55","AP01SDTM":"2019-11-23 18:34:29","AP01EDTM":"2021-02-12 10:44:55","AP02SDTM":"2021-02-12 10:44:55","AP02EDTM":"2022-02-12 16:44:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":812,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":834,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5581,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.26238,"AVALU":"mg/L","BASE2":8.48339,"BASE":9.60691,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.22101,"PCHG2":-14.39299,"CHG":-2.34453,"PCHG":-24.40466,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-05-11 18:34:29","ADY":170,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-346","SUBJID":"id-346","SITEID":"CHN-1","AGE":21,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08004,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-20","TRTSDTM":"2019-11-23 18:34:29","TRTEDTM":"2022-02-12 16:44:55","TRT01SDTM":"2019-11-23 18:34:29","TRT01EDTM":"2021-02-12 10:44:55","TRT02SDTM":"2021-02-12 10:44:55","TRT02EDTM":"2022-02-12 16:44:55","AP01SDTM":"2019-11-23 18:34:29","AP01EDTM":"2021-02-12 10:44:55","AP02SDTM":"2021-02-12 10:44:55","AP02EDTM":"2022-02-12 16:44:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":812,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":834,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6948,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.47141,"AVALU":"mg/L","BASE2":8.48339,"BASE":9.60691,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.98802,"PCHG2":11.64656,"CHG":-0.1355,"PCHG":-1.41042,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-18 18:34:29","ADY":300,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-346","SUBJID":"id-346","SITEID":"CHN-1","AGE":21,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08004,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-20","TRTSDTM":"2019-11-23 18:34:29","TRTEDTM":"2022-02-12 16:44:55","TRT01SDTM":"2019-11-23 18:34:29","TRT01EDTM":"2021-02-12 10:44:55","TRT02SDTM":"2021-02-12 10:44:55","TRT02EDTM":"2022-02-12 16:44:55","AP01SDTM":"2019-11-23 18:34:29","AP01EDTM":"2021-02-12 10:44:55","AP02SDTM":"2021-02-12 10:44:55","AP02EDTM":"2022-02-12 16:44:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":812,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":834,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8269,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.80616,"AVALU":"mg/L","BASE2":8.48339,"BASE":9.60691,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.32277,"PCHG2":3.80476,"CHG":-0.80075,"PCHG":-8.33512,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-13 18:34:29","ADY":721,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-346","SUBJID":"id-346","SITEID":"CHN-1","AGE":21,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08004,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-20","TRTSDTM":"2019-11-23 18:34:29","TRTEDTM":"2022-02-12 16:44:55","TRT01SDTM":"2019-11-23 18:34:29","TRT01EDTM":"2021-02-12 10:44:55","TRT02SDTM":"2021-02-12 10:44:55","TRT02EDTM":"2022-02-12 16:44:55","AP01SDTM":"2019-11-23 18:34:29","AP01EDTM":"2021-02-12 10:44:55","AP02SDTM":"2021-02-12 10:44:55","AP02EDTM":"2022-02-12 16:44:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":812,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":834,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":698,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87971,"AVALU":"g/L","BASE2":2.87971,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-11 18:34:29","ADY":18,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-346","SUBJID":"id-346","SITEID":"CHN-1","AGE":21,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08004,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-20","TRTSDTM":"2019-11-23 18:34:29","TRTEDTM":"2022-02-12 16:44:55","TRT01SDTM":"2019-11-23 18:34:29","TRT01EDTM":"2021-02-12 10:44:55","TRT02SDTM":"2021-02-12 10:44:55","TRT02EDTM":"2022-02-12 16:44:55","AP01SDTM":"2019-11-23 18:34:29","AP01EDTM":"2021-02-12 10:44:55","AP02SDTM":"2021-02-12 10:44:55","AP02EDTM":"2022-02-12 16:44:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":812,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":834,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2482,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84332,"AVALU":"g/L","BASE2":2.87971,"BASE":2.84332,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.03639,"PCHG2":-1.26359,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-14 18:34:29","ADY":21,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-346","SUBJID":"id-346","SITEID":"CHN-1","AGE":21,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08004,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-20","TRTSDTM":"2019-11-23 18:34:29","TRTEDTM":"2022-02-12 16:44:55","TRT01SDTM":"2019-11-23 18:34:29","TRT01EDTM":"2021-02-12 10:44:55","TRT02SDTM":"2021-02-12 10:44:55","TRT02EDTM":"2022-02-12 16:44:55","AP01SDTM":"2019-11-23 18:34:29","AP01EDTM":"2021-02-12 10:44:55","AP02SDTM":"2021-02-12 10:44:55","AP02EDTM":"2022-02-12 16:44:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":812,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":834,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2307,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91987,"AVALU":"g/L","BASE2":2.87971,"BASE":2.84332,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04016,"PCHG2":1.39466,"CHG":0.07655,"PCHG":2.69226,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-06 18:34:29","ADY":135,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-346","SUBJID":"id-346","SITEID":"CHN-1","AGE":21,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08004,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-20","TRTSDTM":"2019-11-23 18:34:29","TRTEDTM":"2022-02-12 16:44:55","TRT01SDTM":"2019-11-23 18:34:29","TRT01EDTM":"2021-02-12 10:44:55","TRT02SDTM":"2021-02-12 10:44:55","TRT02EDTM":"2022-02-12 16:44:55","AP01SDTM":"2019-11-23 18:34:29","AP01EDTM":"2021-02-12 10:44:55","AP02SDTM":"2021-02-12 10:44:55","AP02EDTM":"2022-02-12 16:44:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":812,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":834,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1515,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.12948,"AVALU":"g/L","BASE2":2.87971,"BASE":2.84332,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.24977,"PCHG2":8.67345,"CHG":0.28616,"PCHG":10.06421,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-04-27 18:34:29","ADY":156,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-346","SUBJID":"id-346","SITEID":"CHN-1","AGE":21,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08004,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-20","TRTSDTM":"2019-11-23 18:34:29","TRTEDTM":"2022-02-12 16:44:55","TRT01SDTM":"2019-11-23 18:34:29","TRT01EDTM":"2021-02-12 10:44:55","TRT02SDTM":"2021-02-12 10:44:55","TRT02EDTM":"2022-02-12 16:44:55","AP01SDTM":"2019-11-23 18:34:29","AP01EDTM":"2021-02-12 10:44:55","AP02SDTM":"2021-02-12 10:44:55","AP02EDTM":"2022-02-12 16:44:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":812,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":834,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5103,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96256,"AVALU":"g/L","BASE2":2.87971,"BASE":2.84332,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08285,"PCHG2":2.87696,"CHG":0.11924,"PCHG":4.19354,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-11 18:34:29","ADY":170,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-346","SUBJID":"id-346","SITEID":"CHN-1","AGE":21,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08004,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-20","TRTSDTM":"2019-11-23 18:34:29","TRTEDTM":"2022-02-12 16:44:55","TRT01SDTM":"2019-11-23 18:34:29","TRT01EDTM":"2021-02-12 10:44:55","TRT02SDTM":"2021-02-12 10:44:55","TRT02EDTM":"2022-02-12 16:44:55","AP01SDTM":"2019-11-23 18:34:29","AP01EDTM":"2021-02-12 10:44:55","AP02SDTM":"2021-02-12 10:44:55","AP02EDTM":"2022-02-12 16:44:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":812,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":834,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2909,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97379,"AVALU":"g/L","BASE2":2.87971,"BASE":2.84332,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09408,"PCHG2":3.26702,"CHG":0.13047,"PCHG":4.58859,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-18 18:34:29","ADY":300,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-346","SUBJID":"id-346","SITEID":"CHN-1","AGE":21,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08004,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-20","TRTSDTM":"2019-11-23 18:34:29","TRTEDTM":"2022-02-12 16:44:55","TRT01SDTM":"2019-11-23 18:34:29","TRT01EDTM":"2021-02-12 10:44:55","TRT02SDTM":"2021-02-12 10:44:55","TRT02EDTM":"2022-02-12 16:44:55","AP01SDTM":"2019-11-23 18:34:29","AP01EDTM":"2021-02-12 10:44:55","AP02SDTM":"2021-02-12 10:44:55","AP02EDTM":"2022-02-12 16:44:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":812,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":834,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":765,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8496,"AVALU":"g/L","BASE2":2.87971,"BASE":2.84332,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03011,"PCHG2":-1.04567,"CHG":0.00628,"PCHG":0.2207,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-13 18:34:29","ADY":721,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-347","SUBJID":"id-347","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15631,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-25","TRTSDTM":"2020-09-26 15:42:32","TRTEDTM":"2022-02-17 11:49:19","TRT01SDTM":"2020-09-26 15:42:32","TRT01EDTM":"2021-02-17 05:49:19","TRT02SDTM":"2021-02-17 05:49:19","TRT02EDTM":"2022-02-17 11:49:19","AP01SDTM":"2020-09-26 15:42:32","AP01EDTM":"2021-02-17 05:49:19","AP02SDTM":"2021-02-17 05:49:19","AP02EDTM":"2022-02-17 11:49:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":509,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-16","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":379,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.07902,"AVALU":"U/L","BASE2":31.07902,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-01-25 15:42:32","ADY":121,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-347","SUBJID":"id-347","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15631,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-25","TRTSDTM":"2020-09-26 15:42:32","TRTEDTM":"2022-02-17 11:49:19","TRT01SDTM":"2020-09-26 15:42:32","TRT01EDTM":"2021-02-17 05:49:19","TRT02SDTM":"2021-02-17 05:49:19","TRT02EDTM":"2022-02-17 11:49:19","AP01SDTM":"2020-09-26 15:42:32","AP01EDTM":"2021-02-17 05:49:19","AP02SDTM":"2021-02-17 05:49:19","AP02EDTM":"2022-02-17 11:49:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":509,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-16","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1628,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.04167,"AVALU":"U/L","BASE2":31.07902,"BASE":1.04167,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-30.03734,"PCHG2":-96.64831,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2021-03-09 15:42:32","ADY":164,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-347","SUBJID":"id-347","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15631,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-25","TRTSDTM":"2020-09-26 15:42:32","TRTEDTM":"2022-02-17 11:49:19","TRT01SDTM":"2020-09-26 15:42:32","TRT01EDTM":"2021-02-17 05:49:19","TRT02SDTM":"2021-02-17 05:49:19","TRT02EDTM":"2022-02-17 11:49:19","AP01SDTM":"2020-09-26 15:42:32","AP01EDTM":"2021-02-17 05:49:19","AP02SDTM":"2021-02-17 05:49:19","AP02EDTM":"2022-02-17 11:49:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":509,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-16","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5368,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.32541,"AVALU":"U/L","BASE2":31.07902,"BASE":1.04167,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.75361,"PCHG2":-34.60086,"CHG":19.28374,"PCHG":1851.22637,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-04-18 15:42:32","ADY":204,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-347","SUBJID":"id-347","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15631,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-25","TRTSDTM":"2020-09-26 15:42:32","TRTEDTM":"2022-02-17 11:49:19","TRT01SDTM":"2020-09-26 15:42:32","TRT01EDTM":"2021-02-17 05:49:19","TRT02SDTM":"2021-02-17 05:49:19","TRT02EDTM":"2022-02-17 11:49:19","AP01SDTM":"2020-09-26 15:42:32","AP01EDTM":"2021-02-17 05:49:19","AP02SDTM":"2021-02-17 05:49:19","AP02EDTM":"2022-02-17 11:49:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":509,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-16","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1893,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.19381,"AVALU":"U/L","BASE2":31.07902,"BASE":1.04167,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-26.8852,"PCHG2":-86.50596,"CHG":3.15214,"PCHG":302.60356,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-3","ADTM":"2021-04-19 15:42:32","ADY":205,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-347","SUBJID":"id-347","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15631,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-25","TRTSDTM":"2020-09-26 15:42:32","TRTEDTM":"2022-02-17 11:49:19","TRT01SDTM":"2020-09-26 15:42:32","TRT01EDTM":"2021-02-17 05:49:19","TRT02SDTM":"2021-02-17 05:49:19","TRT02EDTM":"2022-02-17 11:49:19","AP01SDTM":"2020-09-26 15:42:32","AP01EDTM":"2021-02-17 05:49:19","AP02SDTM":"2021-02-17 05:49:19","AP02EDTM":"2022-02-17 11:49:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":509,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-16","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7008,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.25481,"AVALU":"U/L","BASE2":31.07902,"BASE":1.04167,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-29.8242,"PCHG2":-95.96251,"CHG":0.21314,"PCHG":20.46126,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-2","BTOXGR":"-3","ADTM":"2021-06-29 15:42:32","ADY":276,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-347","SUBJID":"id-347","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15631,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-25","TRTSDTM":"2020-09-26 15:42:32","TRTEDTM":"2022-02-17 11:49:19","TRT01SDTM":"2020-09-26 15:42:32","TRT01EDTM":"2021-02-17 05:49:19","TRT02SDTM":"2021-02-17 05:49:19","TRT02EDTM":"2022-02-17 11:49:19","AP01SDTM":"2020-09-26 15:42:32","AP01EDTM":"2021-02-17 05:49:19","AP02SDTM":"2021-02-17 05:49:19","AP02EDTM":"2022-02-17 11:49:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":509,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-16","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7110,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.03394,"AVALU":"U/L","BASE2":31.07902,"BASE":1.04167,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.04507,"PCHG2":-6.58023,"CHG":27.99227,"PCHG":2687.24027,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-09-21 15:42:32","ADY":360,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-347","SUBJID":"id-347","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15631,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-25","TRTSDTM":"2020-09-26 15:42:32","TRTEDTM":"2022-02-17 11:49:19","TRT01SDTM":"2020-09-26 15:42:32","TRT01EDTM":"2021-02-17 05:49:19","TRT02SDTM":"2021-02-17 05:49:19","TRT02EDTM":"2022-02-17 11:49:19","AP01SDTM":"2020-09-26 15:42:32","AP01EDTM":"2021-02-17 05:49:19","AP02SDTM":"2021-02-17 05:49:19","AP02EDTM":"2022-02-17 11:49:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":509,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-16","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3285,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.80782,"AVALU":"U/L","BASE2":31.07902,"BASE":1.04167,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-25.27119,"PCHG2":-81.31272,"CHG":4.76615,"PCHG":457.54722,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-3","ADTM":"2022-01-23 15:42:32","ADY":484,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-347","SUBJID":"id-347","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15631,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-25","TRTSDTM":"2020-09-26 15:42:32","TRTEDTM":"2022-02-17 11:49:19","TRT01SDTM":"2020-09-26 15:42:32","TRT01EDTM":"2021-02-17 05:49:19","TRT02SDTM":"2021-02-17 05:49:19","TRT02EDTM":"2022-02-17 11:49:19","AP01SDTM":"2020-09-26 15:42:32","AP01EDTM":"2021-02-17 05:49:19","AP02SDTM":"2021-02-17 05:49:19","AP02EDTM":"2022-02-17 11:49:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":509,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-16","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7181,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.51671,"AVALU":"mg/L","BASE2":9.51671,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-01-25 15:42:32","ADY":121,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-347","SUBJID":"id-347","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15631,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-25","TRTSDTM":"2020-09-26 15:42:32","TRTEDTM":"2022-02-17 11:49:19","TRT01SDTM":"2020-09-26 15:42:32","TRT01EDTM":"2021-02-17 05:49:19","TRT02SDTM":"2021-02-17 05:49:19","TRT02EDTM":"2022-02-17 11:49:19","AP01SDTM":"2020-09-26 15:42:32","AP01EDTM":"2021-02-17 05:49:19","AP02SDTM":"2021-02-17 05:49:19","AP02EDTM":"2022-02-17 11:49:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":509,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-16","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4001,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.89999,"AVALU":"mg/L","BASE2":9.51671,"BASE":7.89999,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.61672,"PCHG2":-16.98826,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2021-03-09 15:42:32","ADY":164,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-347","SUBJID":"id-347","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15631,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-25","TRTSDTM":"2020-09-26 15:42:32","TRTEDTM":"2022-02-17 11:49:19","TRT01SDTM":"2020-09-26 15:42:32","TRT01EDTM":"2021-02-17 05:49:19","TRT02SDTM":"2021-02-17 05:49:19","TRT02EDTM":"2022-02-17 11:49:19","AP01SDTM":"2020-09-26 15:42:32","AP01EDTM":"2021-02-17 05:49:19","AP02SDTM":"2021-02-17 05:49:19","AP02EDTM":"2022-02-17 11:49:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":509,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-16","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":876,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.12158,"AVALU":"mg/L","BASE2":9.51671,"BASE":7.89999,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.39513,"PCHG2":-4.152,"CHG":1.22159,"PCHG":15.46318,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-04-18 15:42:32","ADY":204,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-347","SUBJID":"id-347","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15631,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-25","TRTSDTM":"2020-09-26 15:42:32","TRTEDTM":"2022-02-17 11:49:19","TRT01SDTM":"2020-09-26 15:42:32","TRT01EDTM":"2021-02-17 05:49:19","TRT02SDTM":"2021-02-17 05:49:19","TRT02EDTM":"2022-02-17 11:49:19","AP01SDTM":"2020-09-26 15:42:32","AP01EDTM":"2021-02-17 05:49:19","AP02SDTM":"2021-02-17 05:49:19","AP02EDTM":"2022-02-17 11:49:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":509,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-16","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2535,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.22866,"AVALU":"mg/L","BASE2":9.51671,"BASE":7.89999,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.71194,"PCHG2":7.48098,"CHG":2.32867,"PCHG":29.47684,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"1","BTOXGR":"-2","ADTM":"2021-04-19 15:42:32","ADY":205,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-347","SUBJID":"id-347","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15631,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-25","TRTSDTM":"2020-09-26 15:42:32","TRTEDTM":"2022-02-17 11:49:19","TRT01SDTM":"2020-09-26 15:42:32","TRT01EDTM":"2021-02-17 05:49:19","TRT02SDTM":"2021-02-17 05:49:19","TRT02EDTM":"2022-02-17 11:49:19","AP01SDTM":"2020-09-26 15:42:32","AP01EDTM":"2021-02-17 05:49:19","AP02SDTM":"2021-02-17 05:49:19","AP02EDTM":"2022-02-17 11:49:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":509,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-16","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2409,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.01215,"AVALU":"mg/L","BASE2":9.51671,"BASE":7.89999,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.50457,"PCHG2":-5.30192,"CHG":1.11216,"PCHG":14.07794,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-06-29 15:42:32","ADY":276,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-347","SUBJID":"id-347","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15631,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-25","TRTSDTM":"2020-09-26 15:42:32","TRTEDTM":"2022-02-17 11:49:19","TRT01SDTM":"2020-09-26 15:42:32","TRT01EDTM":"2021-02-17 05:49:19","TRT02SDTM":"2021-02-17 05:49:19","TRT02EDTM":"2022-02-17 11:49:19","AP01SDTM":"2020-09-26 15:42:32","AP01EDTM":"2021-02-17 05:49:19","AP02SDTM":"2021-02-17 05:49:19","AP02EDTM":"2022-02-17 11:49:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":509,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-16","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3670,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.78846,"AVALU":"mg/L","BASE2":9.51671,"BASE":7.89999,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.72826,"PCHG2":-18.16022,"CHG":-0.11153,"PCHG":-1.4118,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-3","BTOXGR":"-2","ADTM":"2021-09-21 15:42:32","ADY":360,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-347","SUBJID":"id-347","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15631,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-25","TRTSDTM":"2020-09-26 15:42:32","TRTEDTM":"2022-02-17 11:49:19","TRT01SDTM":"2020-09-26 15:42:32","TRT01EDTM":"2021-02-17 05:49:19","TRT02SDTM":"2021-02-17 05:49:19","TRT02EDTM":"2022-02-17 11:49:19","AP01SDTM":"2020-09-26 15:42:32","AP01EDTM":"2021-02-17 05:49:19","AP02SDTM":"2021-02-17 05:49:19","AP02EDTM":"2022-02-17 11:49:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":509,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-16","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7939,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.87265,"AVALU":"mg/L","BASE2":9.51671,"BASE":7.89999,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.35594,"PCHG2":3.74013,"CHG":1.97266,"PCHG":24.97042,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-01-23 15:42:32","ADY":484,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-347","SUBJID":"id-347","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15631,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-25","TRTSDTM":"2020-09-26 15:42:32","TRTEDTM":"2022-02-17 11:49:19","TRT01SDTM":"2020-09-26 15:42:32","TRT01EDTM":"2021-02-17 05:49:19","TRT02SDTM":"2021-02-17 05:49:19","TRT02EDTM":"2022-02-17 11:49:19","AP01SDTM":"2020-09-26 15:42:32","AP01EDTM":"2021-02-17 05:49:19","AP02SDTM":"2021-02-17 05:49:19","AP02EDTM":"2022-02-17 11:49:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":509,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-16","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6304,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83197,"AVALU":"g/L","BASE2":2.83197,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-01-25 15:42:32","ADY":121,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-347","SUBJID":"id-347","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15631,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-25","TRTSDTM":"2020-09-26 15:42:32","TRTEDTM":"2022-02-17 11:49:19","TRT01SDTM":"2020-09-26 15:42:32","TRT01EDTM":"2021-02-17 05:49:19","TRT02SDTM":"2021-02-17 05:49:19","TRT02EDTM":"2022-02-17 11:49:19","AP01SDTM":"2020-09-26 15:42:32","AP01EDTM":"2021-02-17 05:49:19","AP02SDTM":"2021-02-17 05:49:19","AP02EDTM":"2022-02-17 11:49:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":509,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-16","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7822,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.09683,"AVALU":"g/L","BASE2":2.83197,"BASE":3.09683,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.26486,"PCHG2":9.35266,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2021-03-09 15:42:32","ADY":164,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-347","SUBJID":"id-347","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15631,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-25","TRTSDTM":"2020-09-26 15:42:32","TRTEDTM":"2022-02-17 11:49:19","TRT01SDTM":"2020-09-26 15:42:32","TRT01EDTM":"2021-02-17 05:49:19","TRT02SDTM":"2021-02-17 05:49:19","TRT02EDTM":"2022-02-17 11:49:19","AP01SDTM":"2020-09-26 15:42:32","AP01EDTM":"2021-02-17 05:49:19","AP02SDTM":"2021-02-17 05:49:19","AP02EDTM":"2022-02-17 11:49:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":509,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-16","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6203,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75988,"AVALU":"g/L","BASE2":2.83197,"BASE":3.09683,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07209,"PCHG2":-2.54549,"CHG":-0.33695,"PCHG":-10.88053,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-04-18 15:42:32","ADY":204,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-347","SUBJID":"id-347","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15631,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-25","TRTSDTM":"2020-09-26 15:42:32","TRTEDTM":"2022-02-17 11:49:19","TRT01SDTM":"2020-09-26 15:42:32","TRT01EDTM":"2021-02-17 05:49:19","TRT02SDTM":"2021-02-17 05:49:19","TRT02EDTM":"2022-02-17 11:49:19","AP01SDTM":"2020-09-26 15:42:32","AP01EDTM":"2021-02-17 05:49:19","AP02SDTM":"2021-02-17 05:49:19","AP02EDTM":"2022-02-17 11:49:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":509,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-16","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6673,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.72443,"AVALU":"g/L","BASE2":2.83197,"BASE":3.09683,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10754,"PCHG2":-3.79719,"CHG":-0.3724,"PCHG":-12.02518,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-04-19 15:42:32","ADY":205,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-347","SUBJID":"id-347","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15631,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-25","TRTSDTM":"2020-09-26 15:42:32","TRTEDTM":"2022-02-17 11:49:19","TRT01SDTM":"2020-09-26 15:42:32","TRT01EDTM":"2021-02-17 05:49:19","TRT02SDTM":"2021-02-17 05:49:19","TRT02EDTM":"2022-02-17 11:49:19","AP01SDTM":"2020-09-26 15:42:32","AP01EDTM":"2021-02-17 05:49:19","AP02SDTM":"2021-02-17 05:49:19","AP02EDTM":"2022-02-17 11:49:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":509,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-16","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3646,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93814,"AVALU":"g/L","BASE2":2.83197,"BASE":3.09683,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10617,"PCHG2":3.74913,"CHG":-0.15869,"PCHG":-5.12428,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-06-29 15:42:32","ADY":276,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-347","SUBJID":"id-347","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15631,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-25","TRTSDTM":"2020-09-26 15:42:32","TRTEDTM":"2022-02-17 11:49:19","TRT01SDTM":"2020-09-26 15:42:32","TRT01EDTM":"2021-02-17 05:49:19","TRT02SDTM":"2021-02-17 05:49:19","TRT02EDTM":"2022-02-17 11:49:19","AP01SDTM":"2020-09-26 15:42:32","AP01EDTM":"2021-02-17 05:49:19","AP02SDTM":"2021-02-17 05:49:19","AP02EDTM":"2022-02-17 11:49:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":509,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-16","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2336,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92036,"AVALU":"g/L","BASE2":2.83197,"BASE":3.09683,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0884,"PCHG2":3.12136,"CHG":-0.17647,"PCHG":-5.69835,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-09-21 15:42:32","ADY":360,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-347","SUBJID":"id-347","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15631,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-25","TRTSDTM":"2020-09-26 15:42:32","TRTEDTM":"2022-02-17 11:49:19","TRT01SDTM":"2020-09-26 15:42:32","TRT01EDTM":"2021-02-17 05:49:19","TRT02SDTM":"2021-02-17 05:49:19","TRT02EDTM":"2022-02-17 11:49:19","AP01SDTM":"2020-09-26 15:42:32","AP01EDTM":"2021-02-17 05:49:19","AP02SDTM":"2021-02-17 05:49:19","AP02EDTM":"2022-02-17 11:49:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":509,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-16","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2026,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85666,"AVALU":"g/L","BASE2":2.83197,"BASE":3.09683,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02469,"PCHG2":0.872,"CHG":-0.24017,"PCHG":-7.75534,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-01-23 15:42:32","ADY":484,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-351","SUBJID":"id-351","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.36685,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-29","TRTSDTM":"2020-08-01 17:04:14","TRTEDTM":"2023-08-02 11:04:14","TRT01SDTM":"2020-08-01 17:04:14","TRT01EDTM":"2022-08-02 05:04:14","TRT02SDTM":"2022-08-02 05:04:14","TRT02EDTM":"2023-08-02 11:04:14","AP01SDTM":"2020-08-01 17:04:14","AP01EDTM":"2022-08-02 05:04:14","AP02SDTM":"2022-08-02 05:04:14","AP02EDTM":"2023-08-02 11:04:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-02","EOSDY":1096,"LSTALVDT":"2023-08-23","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4595,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.09881,"AVALU":"U/L","BASE2":14.09881,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-31 17:04:14","ADY":395,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-351","SUBJID":"id-351","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.36685,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-29","TRTSDTM":"2020-08-01 17:04:14","TRTEDTM":"2023-08-02 11:04:14","TRT01SDTM":"2020-08-01 17:04:14","TRT01EDTM":"2022-08-02 05:04:14","TRT02SDTM":"2022-08-02 05:04:14","TRT02EDTM":"2023-08-02 11:04:14","AP01SDTM":"2020-08-01 17:04:14","AP01EDTM":"2022-08-02 05:04:14","AP02SDTM":"2022-08-02 05:04:14","AP02EDTM":"2023-08-02 11:04:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-02","EOSDY":1096,"LSTALVDT":"2023-08-23","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7307,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.12641,"AVALU":"U/L","BASE2":14.09881,"BASE":22.12641,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":8.0276,"PCHG2":56.93813,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-21 17:04:14","ADY":477,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-351","SUBJID":"id-351","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.36685,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-29","TRTSDTM":"2020-08-01 17:04:14","TRTEDTM":"2023-08-02 11:04:14","TRT01SDTM":"2020-08-01 17:04:14","TRT01EDTM":"2022-08-02 05:04:14","TRT02SDTM":"2022-08-02 05:04:14","TRT02EDTM":"2023-08-02 11:04:14","AP01SDTM":"2020-08-01 17:04:14","AP01EDTM":"2022-08-02 05:04:14","AP02SDTM":"2022-08-02 05:04:14","AP02EDTM":"2023-08-02 11:04:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-02","EOSDY":1096,"LSTALVDT":"2023-08-23","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5166,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.91762,"AVALU":"U/L","BASE2":14.09881,"BASE":22.12641,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.81881,"PCHG2":98.01399,"CHG":5.79121,"PCHG":26.17328,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-23 17:04:14","ADY":479,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-351","SUBJID":"id-351","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.36685,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-29","TRTSDTM":"2020-08-01 17:04:14","TRTEDTM":"2023-08-02 11:04:14","TRT01SDTM":"2020-08-01 17:04:14","TRT01EDTM":"2022-08-02 05:04:14","TRT02SDTM":"2022-08-02 05:04:14","TRT02EDTM":"2023-08-02 11:04:14","AP01SDTM":"2020-08-01 17:04:14","AP01EDTM":"2022-08-02 05:04:14","AP02SDTM":"2022-08-02 05:04:14","AP02EDTM":"2023-08-02 11:04:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-02","EOSDY":1096,"LSTALVDT":"2023-08-23","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1709,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.96707,"AVALU":"U/L","BASE2":14.09881,"BASE":22.12641,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.13174,"PCHG2":-86.04795,"CHG":-20.15934,"PCHG":-91.10984,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2022-01-05 17:04:14","ADY":522,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-351","SUBJID":"id-351","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.36685,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-29","TRTSDTM":"2020-08-01 17:04:14","TRTEDTM":"2023-08-02 11:04:14","TRT01SDTM":"2020-08-01 17:04:14","TRT01EDTM":"2022-08-02 05:04:14","TRT02SDTM":"2022-08-02 05:04:14","TRT02EDTM":"2023-08-02 11:04:14","AP01SDTM":"2020-08-01 17:04:14","AP01EDTM":"2022-08-02 05:04:14","AP02SDTM":"2022-08-02 05:04:14","AP02EDTM":"2023-08-02 11:04:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-02","EOSDY":1096,"LSTALVDT":"2023-08-23","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5257,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.31682,"AVALU":"U/L","BASE2":14.09881,"BASE":22.12641,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.21801,"PCHG2":86.65984,"CHG":4.19041,"PCHG":18.93848,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-18 17:04:14","ADY":566,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-351","SUBJID":"id-351","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.36685,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-29","TRTSDTM":"2020-08-01 17:04:14","TRTEDTM":"2023-08-02 11:04:14","TRT01SDTM":"2020-08-01 17:04:14","TRT01EDTM":"2022-08-02 05:04:14","TRT02SDTM":"2022-08-02 05:04:14","TRT02EDTM":"2023-08-02 11:04:14","AP01SDTM":"2020-08-01 17:04:14","AP01EDTM":"2022-08-02 05:04:14","AP02SDTM":"2022-08-02 05:04:14","AP02EDTM":"2023-08-02 11:04:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-02","EOSDY":1096,"LSTALVDT":"2023-08-23","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7686,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.69512,"AVALU":"U/L","BASE2":14.09881,"BASE":22.12641,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.40369,"PCHG2":-59.60566,"CHG":-16.43129,"PCHG":-74.26098,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-08-22 17:04:14","ADY":751,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-351","SUBJID":"id-351","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.36685,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-29","TRTSDTM":"2020-08-01 17:04:14","TRTEDTM":"2023-08-02 11:04:14","TRT01SDTM":"2020-08-01 17:04:14","TRT01EDTM":"2022-08-02 05:04:14","TRT02SDTM":"2022-08-02 05:04:14","TRT02EDTM":"2023-08-02 11:04:14","AP01SDTM":"2020-08-01 17:04:14","AP01EDTM":"2022-08-02 05:04:14","AP02SDTM":"2022-08-02 05:04:14","AP02EDTM":"2023-08-02 11:04:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-02","EOSDY":1096,"LSTALVDT":"2023-08-23","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6809,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.99323,"AVALU":"U/L","BASE2":14.09881,"BASE":22.12641,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.10558,"PCHG2":-36.21283,"CHG":-13.13318,"PCHG":-59.35522,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-01 17:04:14","ADY":883,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-351","SUBJID":"id-351","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.36685,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-29","TRTSDTM":"2020-08-01 17:04:14","TRTEDTM":"2023-08-02 11:04:14","TRT01SDTM":"2020-08-01 17:04:14","TRT01EDTM":"2022-08-02 05:04:14","TRT02SDTM":"2022-08-02 05:04:14","TRT02EDTM":"2023-08-02 11:04:14","AP01SDTM":"2020-08-01 17:04:14","AP01EDTM":"2022-08-02 05:04:14","AP02SDTM":"2022-08-02 05:04:14","AP02EDTM":"2023-08-02 11:04:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-02","EOSDY":1096,"LSTALVDT":"2023-08-23","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":81,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.76035,"AVALU":"mg/L","BASE2":7.76035,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-3","ADTM":"2021-08-31 17:04:14","ADY":395,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-351","SUBJID":"id-351","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.36685,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-29","TRTSDTM":"2020-08-01 17:04:14","TRTEDTM":"2023-08-02 11:04:14","TRT01SDTM":"2020-08-01 17:04:14","TRT01EDTM":"2022-08-02 05:04:14","TRT02SDTM":"2022-08-02 05:04:14","TRT02EDTM":"2023-08-02 11:04:14","AP01SDTM":"2020-08-01 17:04:14","AP01EDTM":"2022-08-02 05:04:14","AP02SDTM":"2022-08-02 05:04:14","AP02EDTM":"2023-08-02 11:04:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-02","EOSDY":1096,"LSTALVDT":"2023-08-23","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2812,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.45979,"AVALU":"mg/L","BASE2":7.76035,"BASE":7.45979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.30056,"PCHG2":-3.87303,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2021-11-21 17:04:14","ADY":477,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-351","SUBJID":"id-351","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.36685,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-29","TRTSDTM":"2020-08-01 17:04:14","TRTEDTM":"2023-08-02 11:04:14","TRT01SDTM":"2020-08-01 17:04:14","TRT01EDTM":"2022-08-02 05:04:14","TRT02SDTM":"2022-08-02 05:04:14","TRT02EDTM":"2023-08-02 11:04:14","AP01SDTM":"2020-08-01 17:04:14","AP01EDTM":"2022-08-02 05:04:14","AP02SDTM":"2022-08-02 05:04:14","AP02EDTM":"2023-08-02 11:04:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-02","EOSDY":1096,"LSTALVDT":"2023-08-23","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6268,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.62896,"AVALU":"mg/L","BASE2":7.76035,"BASE":7.45979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.86861,"PCHG2":11.19297,"CHG":1.16917,"PCHG":15.67302,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-11-23 17:04:14","ADY":479,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-351","SUBJID":"id-351","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.36685,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-29","TRTSDTM":"2020-08-01 17:04:14","TRTEDTM":"2023-08-02 11:04:14","TRT01SDTM":"2020-08-01 17:04:14","TRT01EDTM":"2022-08-02 05:04:14","TRT02SDTM":"2022-08-02 05:04:14","TRT02EDTM":"2023-08-02 11:04:14","AP01SDTM":"2020-08-01 17:04:14","AP01EDTM":"2022-08-02 05:04:14","AP02SDTM":"2022-08-02 05:04:14","AP02EDTM":"2023-08-02 11:04:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-02","EOSDY":1096,"LSTALVDT":"2023-08-23","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4264,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.87011,"AVALU":"mg/L","BASE2":7.76035,"BASE":7.45979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.10976,"PCHG2":40.07243,"CHG":3.41032,"PCHG":45.71605,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"4","BTOXGR":"-3","ADTM":"2022-01-05 17:04:14","ADY":522,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-351","SUBJID":"id-351","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.36685,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-29","TRTSDTM":"2020-08-01 17:04:14","TRTEDTM":"2023-08-02 11:04:14","TRT01SDTM":"2020-08-01 17:04:14","TRT01EDTM":"2022-08-02 05:04:14","TRT02SDTM":"2022-08-02 05:04:14","TRT02EDTM":"2023-08-02 11:04:14","AP01SDTM":"2020-08-01 17:04:14","AP01EDTM":"2022-08-02 05:04:14","AP02SDTM":"2022-08-02 05:04:14","AP02EDTM":"2023-08-02 11:04:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-02","EOSDY":1096,"LSTALVDT":"2023-08-23","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5060,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.68224,"AVALU":"mg/L","BASE2":7.76035,"BASE":7.45979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.9219,"PCHG2":11.87956,"CHG":1.22246,"PCHG":16.38728,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2022-02-18 17:04:14","ADY":566,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-351","SUBJID":"id-351","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.36685,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-29","TRTSDTM":"2020-08-01 17:04:14","TRTEDTM":"2023-08-02 11:04:14","TRT01SDTM":"2020-08-01 17:04:14","TRT01EDTM":"2022-08-02 05:04:14","TRT02SDTM":"2022-08-02 05:04:14","TRT02EDTM":"2023-08-02 11:04:14","AP01SDTM":"2020-08-01 17:04:14","AP01EDTM":"2022-08-02 05:04:14","AP02SDTM":"2022-08-02 05:04:14","AP02EDTM":"2023-08-02 11:04:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-02","EOSDY":1096,"LSTALVDT":"2023-08-23","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2627,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.46236,"AVALU":"mg/L","BASE2":7.76035,"BASE":7.45979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.70201,"PCHG2":21.93212,"CHG":2.00257,"PCHG":26.84485,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2022-08-22 17:04:14","ADY":751,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-351","SUBJID":"id-351","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.36685,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-29","TRTSDTM":"2020-08-01 17:04:14","TRTEDTM":"2023-08-02 11:04:14","TRT01SDTM":"2020-08-01 17:04:14","TRT01EDTM":"2022-08-02 05:04:14","TRT02SDTM":"2022-08-02 05:04:14","TRT02EDTM":"2023-08-02 11:04:14","AP01SDTM":"2020-08-01 17:04:14","AP01EDTM":"2022-08-02 05:04:14","AP02SDTM":"2022-08-02 05:04:14","AP02EDTM":"2023-08-02 11:04:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-02","EOSDY":1096,"LSTALVDT":"2023-08-23","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5629,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.09485,"AVALU":"mg/L","BASE2":7.76035,"BASE":7.45979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.3345,"PCHG2":4.31035,"CHG":0.63506,"PCHG":8.51309,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2023-01-01 17:04:14","ADY":883,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-351","SUBJID":"id-351","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.36685,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-29","TRTSDTM":"2020-08-01 17:04:14","TRTEDTM":"2023-08-02 11:04:14","TRT01SDTM":"2020-08-01 17:04:14","TRT01EDTM":"2022-08-02 05:04:14","TRT02SDTM":"2022-08-02 05:04:14","TRT02EDTM":"2023-08-02 11:04:14","AP01SDTM":"2020-08-01 17:04:14","AP01EDTM":"2022-08-02 05:04:14","AP02SDTM":"2022-08-02 05:04:14","AP02EDTM":"2023-08-02 11:04:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-02","EOSDY":1096,"LSTALVDT":"2023-08-23","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4395,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93341,"AVALU":"g/L","BASE2":2.93341,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-31 17:04:14","ADY":395,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-351","SUBJID":"id-351","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.36685,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-29","TRTSDTM":"2020-08-01 17:04:14","TRTEDTM":"2023-08-02 11:04:14","TRT01SDTM":"2020-08-01 17:04:14","TRT01EDTM":"2022-08-02 05:04:14","TRT02SDTM":"2022-08-02 05:04:14","TRT02EDTM":"2023-08-02 11:04:14","AP01SDTM":"2020-08-01 17:04:14","AP01EDTM":"2022-08-02 05:04:14","AP02SDTM":"2022-08-02 05:04:14","AP02EDTM":"2023-08-02 11:04:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-02","EOSDY":1096,"LSTALVDT":"2023-08-23","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1440,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89086,"AVALU":"g/L","BASE2":2.93341,"BASE":2.89086,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.04255,"PCHG2":-1.45052,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-21 17:04:14","ADY":477,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-351","SUBJID":"id-351","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.36685,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-29","TRTSDTM":"2020-08-01 17:04:14","TRTEDTM":"2023-08-02 11:04:14","TRT01SDTM":"2020-08-01 17:04:14","TRT01EDTM":"2022-08-02 05:04:14","TRT02SDTM":"2022-08-02 05:04:14","TRT02EDTM":"2023-08-02 11:04:14","AP01SDTM":"2020-08-01 17:04:14","AP01EDTM":"2022-08-02 05:04:14","AP02SDTM":"2022-08-02 05:04:14","AP02EDTM":"2023-08-02 11:04:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-02","EOSDY":1096,"LSTALVDT":"2023-08-23","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":184,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04689,"AVALU":"g/L","BASE2":2.93341,"BASE":2.89086,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11347,"PCHG2":3.86828,"CHG":0.15602,"PCHG":5.39709,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-11-23 17:04:14","ADY":479,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-351","SUBJID":"id-351","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.36685,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-29","TRTSDTM":"2020-08-01 17:04:14","TRTEDTM":"2023-08-02 11:04:14","TRT01SDTM":"2020-08-01 17:04:14","TRT01EDTM":"2022-08-02 05:04:14","TRT02SDTM":"2022-08-02 05:04:14","TRT02EDTM":"2023-08-02 11:04:14","AP01SDTM":"2020-08-01 17:04:14","AP01EDTM":"2022-08-02 05:04:14","AP02SDTM":"2022-08-02 05:04:14","AP02EDTM":"2023-08-02 11:04:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-02","EOSDY":1096,"LSTALVDT":"2023-08-23","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4219,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80337,"AVALU":"g/L","BASE2":2.93341,"BASE":2.89086,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13004,"PCHG2":-4.43309,"CHG":-0.08749,"PCHG":-3.02647,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-05 17:04:14","ADY":522,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-351","SUBJID":"id-351","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.36685,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-29","TRTSDTM":"2020-08-01 17:04:14","TRTEDTM":"2023-08-02 11:04:14","TRT01SDTM":"2020-08-01 17:04:14","TRT01EDTM":"2022-08-02 05:04:14","TRT02SDTM":"2022-08-02 05:04:14","TRT02EDTM":"2023-08-02 11:04:14","AP01SDTM":"2020-08-01 17:04:14","AP01EDTM":"2022-08-02 05:04:14","AP02SDTM":"2022-08-02 05:04:14","AP02EDTM":"2023-08-02 11:04:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-02","EOSDY":1096,"LSTALVDT":"2023-08-23","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2976,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95498,"AVALU":"g/L","BASE2":2.93341,"BASE":2.89086,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02157,"PCHG2":0.7352,"CHG":0.06412,"PCHG":2.21789,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-18 17:04:14","ADY":566,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-351","SUBJID":"id-351","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.36685,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-29","TRTSDTM":"2020-08-01 17:04:14","TRTEDTM":"2023-08-02 11:04:14","TRT01SDTM":"2020-08-01 17:04:14","TRT01EDTM":"2022-08-02 05:04:14","TRT02SDTM":"2022-08-02 05:04:14","TRT02EDTM":"2023-08-02 11:04:14","AP01SDTM":"2020-08-01 17:04:14","AP01EDTM":"2022-08-02 05:04:14","AP02SDTM":"2022-08-02 05:04:14","AP02EDTM":"2023-08-02 11:04:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-02","EOSDY":1096,"LSTALVDT":"2023-08-23","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4739,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.14172,"AVALU":"g/L","BASE2":2.93341,"BASE":2.89086,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.2083,"PCHG2":7.10099,"CHG":0.25085,"PCHG":8.67738,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-08-22 17:04:14","ADY":751,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-351","SUBJID":"id-351","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.36685,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-29","TRTSDTM":"2020-08-01 17:04:14","TRTEDTM":"2023-08-02 11:04:14","TRT01SDTM":"2020-08-01 17:04:14","TRT01EDTM":"2022-08-02 05:04:14","TRT02SDTM":"2022-08-02 05:04:14","TRT02EDTM":"2023-08-02 11:04:14","AP01SDTM":"2020-08-01 17:04:14","AP01EDTM":"2022-08-02 05:04:14","AP02SDTM":"2022-08-02 05:04:14","AP02EDTM":"2023-08-02 11:04:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-02","EOSDY":1096,"LSTALVDT":"2023-08-23","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":955,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94323,"AVALU":"g/L","BASE2":2.93341,"BASE":2.89086,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00981,"PCHG2":0.33452,"CHG":0.05236,"PCHG":1.81132,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-01 17:04:14","ADY":883,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-360","SUBJID":"id-360","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84995,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-10","TRTSDTM":"2020-05-12 21:14:06","TRTEDTM":"2023-05-13 15:14:06","TRT01SDTM":"2020-05-12 21:14:06","TRT01EDTM":"2022-05-13 09:14:06","TRT02SDTM":"2022-05-13 09:14:06","TRT02EDTM":"2023-05-13 15:14:06","AP01SDTM":"2020-05-12 21:14:06","AP01EDTM":"2022-05-13 09:14:06","AP02SDTM":"2022-05-13 09:14:06","AP02EDTM":"2023-05-13 15:14:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-13","EOSDY":1096,"LSTALVDT":"2023-06-06","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3108,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.07168,"AVALU":"U/L","BASE2":22.07168,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-03 21:14:06","ADY":22,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-360","SUBJID":"id-360","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84995,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-10","TRTSDTM":"2020-05-12 21:14:06","TRTEDTM":"2023-05-13 15:14:06","TRT01SDTM":"2020-05-12 21:14:06","TRT01EDTM":"2022-05-13 09:14:06","TRT02SDTM":"2022-05-13 09:14:06","TRT02EDTM":"2023-05-13 15:14:06","AP01SDTM":"2020-05-12 21:14:06","AP01EDTM":"2022-05-13 09:14:06","AP02SDTM":"2022-05-13 09:14:06","AP02EDTM":"2023-05-13 15:14:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-13","EOSDY":1096,"LSTALVDT":"2023-06-06","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5910,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.63346,"AVALU":"U/L","BASE2":22.07168,"BASE":18.63346,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-3.43822,"PCHG2":-15.57751,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-15 21:14:06","ADY":95,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-360","SUBJID":"id-360","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84995,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-10","TRTSDTM":"2020-05-12 21:14:06","TRTEDTM":"2023-05-13 15:14:06","TRT01SDTM":"2020-05-12 21:14:06","TRT01EDTM":"2022-05-13 09:14:06","TRT02SDTM":"2022-05-13 09:14:06","TRT02EDTM":"2023-05-13 15:14:06","AP01SDTM":"2020-05-12 21:14:06","AP01EDTM":"2022-05-13 09:14:06","AP02SDTM":"2022-05-13 09:14:06","AP02EDTM":"2023-05-13 15:14:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-13","EOSDY":1096,"LSTALVDT":"2023-06-06","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5716,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.63898,"AVALU":"U/L","BASE2":22.07168,"BASE":18.63346,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.43269,"PCHG2":-20.08318,"CHG":-0.99448,"PCHG":-5.33704,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-28 21:14:06","ADY":442,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-360","SUBJID":"id-360","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84995,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-10","TRTSDTM":"2020-05-12 21:14:06","TRTEDTM":"2023-05-13 15:14:06","TRT01SDTM":"2020-05-12 21:14:06","TRT01EDTM":"2022-05-13 09:14:06","TRT02SDTM":"2022-05-13 09:14:06","TRT02EDTM":"2023-05-13 15:14:06","AP01SDTM":"2020-05-12 21:14:06","AP01EDTM":"2022-05-13 09:14:06","AP02SDTM":"2022-05-13 09:14:06","AP02EDTM":"2023-05-13 15:14:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-13","EOSDY":1096,"LSTALVDT":"2023-06-06","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2923,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.74128,"AVALU":"U/L","BASE2":22.07168,"BASE":18.63346,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.3304,"PCHG2":-78.51872,"CHG":-13.89218,"PCHG":-74.55502,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-04-01 21:14:06","ADY":689,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-360","SUBJID":"id-360","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84995,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-10","TRTSDTM":"2020-05-12 21:14:06","TRTEDTM":"2023-05-13 15:14:06","TRT01SDTM":"2020-05-12 21:14:06","TRT01EDTM":"2022-05-13 09:14:06","TRT02SDTM":"2022-05-13 09:14:06","TRT02EDTM":"2023-05-13 15:14:06","AP01SDTM":"2020-05-12 21:14:06","AP01EDTM":"2022-05-13 09:14:06","AP02SDTM":"2022-05-13 09:14:06","AP02EDTM":"2023-05-13 15:14:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-13","EOSDY":1096,"LSTALVDT":"2023-06-06","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1496,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.01935,"AVALU":"U/L","BASE2":22.07168,"BASE":18.63346,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.05232,"PCHG2":-54.60538,"CHG":-8.6141,"PCHG":-46.22923,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-01 21:14:06","ADY":780,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-360","SUBJID":"id-360","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84995,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-10","TRTSDTM":"2020-05-12 21:14:06","TRTEDTM":"2023-05-13 15:14:06","TRT01SDTM":"2020-05-12 21:14:06","TRT01EDTM":"2022-05-13 09:14:06","TRT02SDTM":"2022-05-13 09:14:06","TRT02EDTM":"2023-05-13 15:14:06","AP01SDTM":"2020-05-12 21:14:06","AP01EDTM":"2022-05-13 09:14:06","AP02SDTM":"2022-05-13 09:14:06","AP02EDTM":"2023-05-13 15:14:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-13","EOSDY":1096,"LSTALVDT":"2023-06-06","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1453,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":40.11596,"AVALU":"U/L","BASE2":22.07168,"BASE":18.63346,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.04428,"PCHG2":81.7531,"CHG":21.4825,"PCHG":115.28991,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-20 21:14:06","ADY":861,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-360","SUBJID":"id-360","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84995,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-10","TRTSDTM":"2020-05-12 21:14:06","TRTEDTM":"2023-05-13 15:14:06","TRT01SDTM":"2020-05-12 21:14:06","TRT01EDTM":"2022-05-13 09:14:06","TRT02SDTM":"2022-05-13 09:14:06","TRT02EDTM":"2023-05-13 15:14:06","AP01SDTM":"2020-05-12 21:14:06","AP01EDTM":"2022-05-13 09:14:06","AP02SDTM":"2022-05-13 09:14:06","AP02EDTM":"2023-05-13 15:14:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-13","EOSDY":1096,"LSTALVDT":"2023-06-06","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1597,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.10433,"AVALU":"U/L","BASE2":22.07168,"BASE":18.63346,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.03265,"PCHG2":4.67863,"CHG":4.47087,"PCHG":23.99378,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-28 21:14:06","ADY":1022,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-360","SUBJID":"id-360","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84995,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-10","TRTSDTM":"2020-05-12 21:14:06","TRTEDTM":"2023-05-13 15:14:06","TRT01SDTM":"2020-05-12 21:14:06","TRT01EDTM":"2022-05-13 09:14:06","TRT02SDTM":"2022-05-13 09:14:06","TRT02EDTM":"2023-05-13 15:14:06","AP01SDTM":"2020-05-12 21:14:06","AP01EDTM":"2022-05-13 09:14:06","AP02SDTM":"2022-05-13 09:14:06","AP02EDTM":"2023-05-13 15:14:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-13","EOSDY":1096,"LSTALVDT":"2023-06-06","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2319,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.53331,"AVALU":"mg/L","BASE2":8.53331,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-06-03 21:14:06","ADY":22,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-360","SUBJID":"id-360","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84995,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-10","TRTSDTM":"2020-05-12 21:14:06","TRTEDTM":"2023-05-13 15:14:06","TRT01SDTM":"2020-05-12 21:14:06","TRT01EDTM":"2022-05-13 09:14:06","TRT02SDTM":"2022-05-13 09:14:06","TRT02EDTM":"2023-05-13 15:14:06","AP01SDTM":"2020-05-12 21:14:06","AP01EDTM":"2022-05-13 09:14:06","AP02SDTM":"2022-05-13 09:14:06","AP02EDTM":"2023-05-13 15:14:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-13","EOSDY":1096,"LSTALVDT":"2023-06-06","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2138,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.47808,"AVALU":"mg/L","BASE2":8.53331,"BASE":10.47808,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.94477,"PCHG2":22.79035,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-08-15 21:14:06","ADY":95,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-360","SUBJID":"id-360","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84995,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-10","TRTSDTM":"2020-05-12 21:14:06","TRTEDTM":"2023-05-13 15:14:06","TRT01SDTM":"2020-05-12 21:14:06","TRT01EDTM":"2022-05-13 09:14:06","TRT02SDTM":"2022-05-13 09:14:06","TRT02EDTM":"2023-05-13 15:14:06","AP01SDTM":"2020-05-12 21:14:06","AP01EDTM":"2022-05-13 09:14:06","AP02SDTM":"2022-05-13 09:14:06","AP02EDTM":"2023-05-13 15:14:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-13","EOSDY":1096,"LSTALVDT":"2023-06-06","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5791,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.44274,"AVALU":"mg/L","BASE2":8.53331,"BASE":10.47808,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.90943,"PCHG2":10.65736,"CHG":-1.03535,"PCHG":-9.88106,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-07-28 21:14:06","ADY":442,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-360","SUBJID":"id-360","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84995,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-10","TRTSDTM":"2020-05-12 21:14:06","TRTEDTM":"2023-05-13 15:14:06","TRT01SDTM":"2020-05-12 21:14:06","TRT01EDTM":"2022-05-13 09:14:06","TRT02SDTM":"2022-05-13 09:14:06","TRT02EDTM":"2023-05-13 15:14:06","AP01SDTM":"2020-05-12 21:14:06","AP01EDTM":"2022-05-13 09:14:06","AP02SDTM":"2022-05-13 09:14:06","AP02EDTM":"2023-05-13 15:14:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-13","EOSDY":1096,"LSTALVDT":"2023-06-06","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":238,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.98884,"AVALU":"mg/L","BASE2":8.53331,"BASE":10.47808,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.45553,"PCHG2":5.33828,"CHG":-1.48924,"PCHG":-14.2129,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2022-04-01 21:14:06","ADY":689,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-360","SUBJID":"id-360","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84995,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-10","TRTSDTM":"2020-05-12 21:14:06","TRTEDTM":"2023-05-13 15:14:06","TRT01SDTM":"2020-05-12 21:14:06","TRT01EDTM":"2022-05-13 09:14:06","TRT02SDTM":"2022-05-13 09:14:06","TRT02EDTM":"2023-05-13 15:14:06","AP01SDTM":"2020-05-12 21:14:06","AP01EDTM":"2022-05-13 09:14:06","AP02SDTM":"2022-05-13 09:14:06","AP02EDTM":"2023-05-13 15:14:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-13","EOSDY":1096,"LSTALVDT":"2023-06-06","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7747,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.87618,"AVALU":"mg/L","BASE2":8.53331,"BASE":10.47808,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.34287,"PCHG2":15.73679,"CHG":-0.6019,"PCHG":-5.74439,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2022-07-01 21:14:06","ADY":780,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-360","SUBJID":"id-360","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84995,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-10","TRTSDTM":"2020-05-12 21:14:06","TRTEDTM":"2023-05-13 15:14:06","TRT01SDTM":"2020-05-12 21:14:06","TRT01EDTM":"2022-05-13 09:14:06","TRT02SDTM":"2022-05-13 09:14:06","TRT02EDTM":"2023-05-13 15:14:06","AP01SDTM":"2020-05-12 21:14:06","AP01EDTM":"2022-05-13 09:14:06","AP02SDTM":"2022-05-13 09:14:06","AP02EDTM":"2023-05-13 15:14:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-13","EOSDY":1096,"LSTALVDT":"2023-06-06","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7364,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.9988,"AVALU":"mg/L","BASE2":8.53331,"BASE":10.47808,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.53451,"PCHG2":-17.98255,"CHG":-3.47928,"PCHG":-33.20529,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-1","BTOXGR":"1","ADTM":"2022-09-20 21:14:06","ADY":861,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-360","SUBJID":"id-360","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84995,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-10","TRTSDTM":"2020-05-12 21:14:06","TRTEDTM":"2023-05-13 15:14:06","TRT01SDTM":"2020-05-12 21:14:06","TRT01EDTM":"2022-05-13 09:14:06","TRT02SDTM":"2022-05-13 09:14:06","TRT02EDTM":"2023-05-13 15:14:06","AP01SDTM":"2020-05-12 21:14:06","AP01EDTM":"2022-05-13 09:14:06","AP02SDTM":"2022-05-13 09:14:06","AP02EDTM":"2023-05-13 15:14:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-13","EOSDY":1096,"LSTALVDT":"2023-06-06","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2722,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.73328,"AVALU":"mg/L","BASE2":8.53331,"BASE":10.47808,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.19997,"PCHG2":25.78096,"CHG":0.2552,"PCHG":2.43554,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"1","ADTM":"2023-02-28 21:14:06","ADY":1022,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-360","SUBJID":"id-360","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84995,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-10","TRTSDTM":"2020-05-12 21:14:06","TRTEDTM":"2023-05-13 15:14:06","TRT01SDTM":"2020-05-12 21:14:06","TRT01EDTM":"2022-05-13 09:14:06","TRT02SDTM":"2022-05-13 09:14:06","TRT02EDTM":"2023-05-13 15:14:06","AP01SDTM":"2020-05-12 21:14:06","AP01EDTM":"2022-05-13 09:14:06","AP02SDTM":"2022-05-13 09:14:06","AP02EDTM":"2023-05-13 15:14:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-13","EOSDY":1096,"LSTALVDT":"2023-06-06","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1587,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78897,"AVALU":"g/L","BASE2":2.78897,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-03 21:14:06","ADY":22,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-360","SUBJID":"id-360","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84995,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-10","TRTSDTM":"2020-05-12 21:14:06","TRTEDTM":"2023-05-13 15:14:06","TRT01SDTM":"2020-05-12 21:14:06","TRT01EDTM":"2022-05-13 09:14:06","TRT02SDTM":"2022-05-13 09:14:06","TRT02EDTM":"2023-05-13 15:14:06","AP01SDTM":"2020-05-12 21:14:06","AP01EDTM":"2022-05-13 09:14:06","AP02SDTM":"2022-05-13 09:14:06","AP02EDTM":"2023-05-13 15:14:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-13","EOSDY":1096,"LSTALVDT":"2023-06-06","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7690,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78605,"AVALU":"g/L","BASE2":2.78897,"BASE":2.78605,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.00293,"PCHG2":-0.10493,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-15 21:14:06","ADY":95,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-360","SUBJID":"id-360","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84995,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-10","TRTSDTM":"2020-05-12 21:14:06","TRTEDTM":"2023-05-13 15:14:06","TRT01SDTM":"2020-05-12 21:14:06","TRT01EDTM":"2022-05-13 09:14:06","TRT02SDTM":"2022-05-13 09:14:06","TRT02EDTM":"2023-05-13 15:14:06","AP01SDTM":"2020-05-12 21:14:06","AP01EDTM":"2022-05-13 09:14:06","AP02SDTM":"2022-05-13 09:14:06","AP02EDTM":"2023-05-13 15:14:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-13","EOSDY":1096,"LSTALVDT":"2023-06-06","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7018,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85196,"AVALU":"g/L","BASE2":2.78897,"BASE":2.78605,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06299,"PCHG2":2.25845,"CHG":0.06591,"PCHG":2.36587,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-28 21:14:06","ADY":442,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-360","SUBJID":"id-360","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84995,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-10","TRTSDTM":"2020-05-12 21:14:06","TRTEDTM":"2023-05-13 15:14:06","TRT01SDTM":"2020-05-12 21:14:06","TRT01EDTM":"2022-05-13 09:14:06","TRT02SDTM":"2022-05-13 09:14:06","TRT02EDTM":"2023-05-13 15:14:06","AP01SDTM":"2020-05-12 21:14:06","AP01EDTM":"2022-05-13 09:14:06","AP02SDTM":"2022-05-13 09:14:06","AP02EDTM":"2023-05-13 15:14:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-13","EOSDY":1096,"LSTALVDT":"2023-06-06","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3785,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96984,"AVALU":"g/L","BASE2":2.78897,"BASE":2.78605,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18086,"PCHG2":6.48495,"CHG":0.18379,"PCHG":6.5968,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-01 21:14:06","ADY":689,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-360","SUBJID":"id-360","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84995,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-10","TRTSDTM":"2020-05-12 21:14:06","TRTEDTM":"2023-05-13 15:14:06","TRT01SDTM":"2020-05-12 21:14:06","TRT01EDTM":"2022-05-13 09:14:06","TRT02SDTM":"2022-05-13 09:14:06","TRT02EDTM":"2023-05-13 15:14:06","AP01SDTM":"2020-05-12 21:14:06","AP01EDTM":"2022-05-13 09:14:06","AP02SDTM":"2022-05-13 09:14:06","AP02EDTM":"2023-05-13 15:14:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-13","EOSDY":1096,"LSTALVDT":"2023-06-06","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":799,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.11152,"AVALU":"g/L","BASE2":2.78897,"BASE":2.78605,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.32255,"PCHG2":11.56522,"CHG":0.32548,"PCHG":11.68241,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-07-01 21:14:06","ADY":780,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-360","SUBJID":"id-360","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84995,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-10","TRTSDTM":"2020-05-12 21:14:06","TRTEDTM":"2023-05-13 15:14:06","TRT01SDTM":"2020-05-12 21:14:06","TRT01EDTM":"2022-05-13 09:14:06","TRT02SDTM":"2022-05-13 09:14:06","TRT02EDTM":"2023-05-13 15:14:06","AP01SDTM":"2020-05-12 21:14:06","AP01EDTM":"2022-05-13 09:14:06","AP02SDTM":"2022-05-13 09:14:06","AP02EDTM":"2023-05-13 15:14:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-13","EOSDY":1096,"LSTALVDT":"2023-06-06","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5951,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98409,"AVALU":"g/L","BASE2":2.78897,"BASE":2.78605,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.19511,"PCHG2":6.99594,"CHG":0.19804,"PCHG":7.10832,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-20 21:14:06","ADY":861,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-360","SUBJID":"id-360","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84995,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-10","TRTSDTM":"2020-05-12 21:14:06","TRTEDTM":"2023-05-13 15:14:06","TRT01SDTM":"2020-05-12 21:14:06","TRT01EDTM":"2022-05-13 09:14:06","TRT02SDTM":"2022-05-13 09:14:06","TRT02EDTM":"2023-05-13 15:14:06","AP01SDTM":"2020-05-12 21:14:06","AP01EDTM":"2022-05-13 09:14:06","AP02SDTM":"2022-05-13 09:14:06","AP02EDTM":"2023-05-13 15:14:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-13","EOSDY":1096,"LSTALVDT":"2023-06-06","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8013,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8993,"AVALU":"g/L","BASE2":2.78897,"BASE":2.78605,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11032,"PCHG2":3.95568,"CHG":0.11325,"PCHG":4.06487,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-28 21:14:06","ADY":1022,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-371","SUBJID":"id-371","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.32686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-07","TRTSDTM":"2021-02-09 05:50:09","TRTEDTM":"2024-02-09 23:50:09","TRT01SDTM":"2021-02-09 05:50:09","TRT01EDTM":"2023-02-09 17:50:09","TRT02SDTM":"2023-02-09 17:50:09","TRT02EDTM":"2024-02-09 23:50:09","AP01SDTM":"2021-02-09 05:50:09","AP01EDTM":"2023-02-09 17:50:09","AP02SDTM":"2023-02-09 17:50:09","AP02EDTM":"2024-02-09 23:50:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-09","EOSDY":1096,"LSTALVDT":"2024-02-29","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2538,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.45011,"AVALU":"U/L","BASE2":18.45011,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-04-12 05:50:09","ADY":62,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-371","SUBJID":"id-371","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.32686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-07","TRTSDTM":"2021-02-09 05:50:09","TRTEDTM":"2024-02-09 23:50:09","TRT01SDTM":"2021-02-09 05:50:09","TRT01EDTM":"2023-02-09 17:50:09","TRT02SDTM":"2023-02-09 17:50:09","TRT02EDTM":"2024-02-09 23:50:09","AP01SDTM":"2021-02-09 05:50:09","AP01EDTM":"2023-02-09 17:50:09","AP02SDTM":"2023-02-09 17:50:09","AP02EDTM":"2024-02-09 23:50:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-09","EOSDY":1096,"LSTALVDT":"2024-02-29","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8382,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.92666,"AVALU":"U/L","BASE2":18.45011,"BASE":5.92666,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-12.52345,"PCHG2":-67.87738,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2021-05-01 05:50:09","ADY":81,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-371","SUBJID":"id-371","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.32686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-07","TRTSDTM":"2021-02-09 05:50:09","TRTEDTM":"2024-02-09 23:50:09","TRT01SDTM":"2021-02-09 05:50:09","TRT01EDTM":"2023-02-09 17:50:09","TRT02SDTM":"2023-02-09 17:50:09","TRT02EDTM":"2024-02-09 23:50:09","AP01SDTM":"2021-02-09 05:50:09","AP01EDTM":"2023-02-09 17:50:09","AP02SDTM":"2023-02-09 17:50:09","AP02EDTM":"2024-02-09 23:50:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-09","EOSDY":1096,"LSTALVDT":"2024-02-29","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5208,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.74842,"AVALU":"U/L","BASE2":18.45011,"BASE":5.92666,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.29832,"PCHG2":66.65717,"CHG":24.82177,"PCHG":418.81555,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-12-20 05:50:09","ADY":314,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-371","SUBJID":"id-371","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.32686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-07","TRTSDTM":"2021-02-09 05:50:09","TRTEDTM":"2024-02-09 23:50:09","TRT01SDTM":"2021-02-09 05:50:09","TRT01EDTM":"2023-02-09 17:50:09","TRT02SDTM":"2023-02-09 17:50:09","TRT02EDTM":"2024-02-09 23:50:09","AP01SDTM":"2021-02-09 05:50:09","AP01EDTM":"2023-02-09 17:50:09","AP02SDTM":"2023-02-09 17:50:09","AP02EDTM":"2024-02-09 23:50:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-09","EOSDY":1096,"LSTALVDT":"2024-02-29","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1688,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.78095,"AVALU":"U/L","BASE2":18.45011,"BASE":5.92666,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.66915,"PCHG2":-3.62682,"CHG":11.8543,"PCHG":200.01653,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-07-29 05:50:09","ADY":535,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-371","SUBJID":"id-371","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.32686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-07","TRTSDTM":"2021-02-09 05:50:09","TRTEDTM":"2024-02-09 23:50:09","TRT01SDTM":"2021-02-09 05:50:09","TRT01EDTM":"2023-02-09 17:50:09","TRT02SDTM":"2023-02-09 17:50:09","TRT02EDTM":"2024-02-09 23:50:09","AP01SDTM":"2021-02-09 05:50:09","AP01EDTM":"2023-02-09 17:50:09","AP02SDTM":"2023-02-09 17:50:09","AP02EDTM":"2024-02-09 23:50:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-09","EOSDY":1096,"LSTALVDT":"2024-02-29","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1926,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.85137,"AVALU":"U/L","BASE2":18.45011,"BASE":5.92666,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.40127,"PCHG2":23.85497,"CHG":16.92472,"PCHG":285.56929,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-09-16 05:50:09","ADY":584,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-371","SUBJID":"id-371","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.32686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-07","TRTSDTM":"2021-02-09 05:50:09","TRTEDTM":"2024-02-09 23:50:09","TRT01SDTM":"2021-02-09 05:50:09","TRT01EDTM":"2023-02-09 17:50:09","TRT02SDTM":"2023-02-09 17:50:09","TRT02EDTM":"2024-02-09 23:50:09","AP01SDTM":"2021-02-09 05:50:09","AP01EDTM":"2023-02-09 17:50:09","AP02SDTM":"2023-02-09 17:50:09","AP02EDTM":"2024-02-09 23:50:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-09","EOSDY":1096,"LSTALVDT":"2024-02-29","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5407,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.3311,"AVALU":"U/L","BASE2":18.45011,"BASE":5.92666,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.88099,"PCHG2":75.2353,"CHG":26.40444,"PCHG":445.51987,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-09-26 05:50:09","ADY":594,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-371","SUBJID":"id-371","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.32686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-07","TRTSDTM":"2021-02-09 05:50:09","TRTEDTM":"2024-02-09 23:50:09","TRT01SDTM":"2021-02-09 05:50:09","TRT01EDTM":"2023-02-09 17:50:09","TRT02SDTM":"2023-02-09 17:50:09","TRT02EDTM":"2024-02-09 23:50:09","AP01SDTM":"2021-02-09 05:50:09","AP01EDTM":"2023-02-09 17:50:09","AP02SDTM":"2023-02-09 17:50:09","AP02EDTM":"2024-02-09 23:50:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-09","EOSDY":1096,"LSTALVDT":"2024-02-29","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4633,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.57986,"AVALU":"U/L","BASE2":18.45011,"BASE":5.92666,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.12976,"PCHG2":16.96335,"CHG":15.6532,"PCHG":264.11519,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2023-10-27 05:50:09","ADY":990,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-371","SUBJID":"id-371","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.32686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-07","TRTSDTM":"2021-02-09 05:50:09","TRTEDTM":"2024-02-09 23:50:09","TRT01SDTM":"2021-02-09 05:50:09","TRT01EDTM":"2023-02-09 17:50:09","TRT02SDTM":"2023-02-09 17:50:09","TRT02EDTM":"2024-02-09 23:50:09","AP01SDTM":"2021-02-09 05:50:09","AP01EDTM":"2023-02-09 17:50:09","AP02SDTM":"2023-02-09 17:50:09","AP02EDTM":"2024-02-09 23:50:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-09","EOSDY":1096,"LSTALVDT":"2024-02-29","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1039,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.32273,"AVALU":"mg/L","BASE2":10.32273,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"","ATOXGR":"2","BTOXGR":"-4","ADTM":"2021-04-12 05:50:09","ADY":62,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-371","SUBJID":"id-371","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.32686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-07","TRTSDTM":"2021-02-09 05:50:09","TRTEDTM":"2024-02-09 23:50:09","TRT01SDTM":"2021-02-09 05:50:09","TRT01EDTM":"2023-02-09 17:50:09","TRT02SDTM":"2023-02-09 17:50:09","TRT02EDTM":"2024-02-09 23:50:09","AP01SDTM":"2021-02-09 05:50:09","AP01EDTM":"2023-02-09 17:50:09","AP02SDTM":"2023-02-09 17:50:09","AP02EDTM":"2024-02-09 23:50:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-09","EOSDY":1096,"LSTALVDT":"2024-02-29","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5209,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.1369,"AVALU":"mg/L","BASE2":10.32273,"BASE":7.1369,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-3.18583,"PCHG2":-30.86225,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-4","BTOXGR":"-4","ADTM":"2021-05-01 05:50:09","ADY":81,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-371","SUBJID":"id-371","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.32686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-07","TRTSDTM":"2021-02-09 05:50:09","TRTEDTM":"2024-02-09 23:50:09","TRT01SDTM":"2021-02-09 05:50:09","TRT01EDTM":"2023-02-09 17:50:09","TRT02SDTM":"2023-02-09 17:50:09","TRT02EDTM":"2024-02-09 23:50:09","AP01SDTM":"2021-02-09 05:50:09","AP01EDTM":"2023-02-09 17:50:09","AP02SDTM":"2023-02-09 17:50:09","AP02EDTM":"2024-02-09 23:50:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-09","EOSDY":1096,"LSTALVDT":"2024-02-29","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4818,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.08523,"AVALU":"mg/L","BASE2":10.32273,"BASE":7.1369,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.2375,"PCHG2":-11.98812,"CHG":1.94832,"PCHG":27.29931,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-12-20 05:50:09","ADY":314,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-371","SUBJID":"id-371","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.32686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-07","TRTSDTM":"2021-02-09 05:50:09","TRTEDTM":"2024-02-09 23:50:09","TRT01SDTM":"2021-02-09 05:50:09","TRT01EDTM":"2023-02-09 17:50:09","TRT02SDTM":"2023-02-09 17:50:09","TRT02EDTM":"2024-02-09 23:50:09","AP01SDTM":"2021-02-09 05:50:09","AP01EDTM":"2023-02-09 17:50:09","AP02SDTM":"2023-02-09 17:50:09","AP02EDTM":"2024-02-09 23:50:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-09","EOSDY":1096,"LSTALVDT":"2024-02-29","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2836,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.31969,"AVALU":"mg/L","BASE2":10.32273,"BASE":7.1369,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.00303,"PCHG2":-19.40411,"CHG":1.18279,"PCHG":16.5729,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2022-07-29 05:50:09","ADY":535,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-371","SUBJID":"id-371","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.32686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-07","TRTSDTM":"2021-02-09 05:50:09","TRTEDTM":"2024-02-09 23:50:09","TRT01SDTM":"2021-02-09 05:50:09","TRT01EDTM":"2023-02-09 17:50:09","TRT02SDTM":"2023-02-09 17:50:09","TRT02EDTM":"2024-02-09 23:50:09","AP01SDTM":"2021-02-09 05:50:09","AP01EDTM":"2023-02-09 17:50:09","AP02SDTM":"2023-02-09 17:50:09","AP02EDTM":"2024-02-09 23:50:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-09","EOSDY":1096,"LSTALVDT":"2024-02-29","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6870,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.55853,"AVALU":"mg/L","BASE2":10.32273,"BASE":7.1369,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.7642,"PCHG2":-7.40304,"CHG":2.42163,"PCHG":33.93112,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2022-09-16 05:50:09","ADY":584,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-371","SUBJID":"id-371","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.32686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-07","TRTSDTM":"2021-02-09 05:50:09","TRTEDTM":"2024-02-09 23:50:09","TRT01SDTM":"2021-02-09 05:50:09","TRT01EDTM":"2023-02-09 17:50:09","TRT02SDTM":"2023-02-09 17:50:09","TRT02EDTM":"2024-02-09 23:50:09","AP01SDTM":"2021-02-09 05:50:09","AP01EDTM":"2023-02-09 17:50:09","AP02SDTM":"2023-02-09 17:50:09","AP02EDTM":"2024-02-09 23:50:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-09","EOSDY":1096,"LSTALVDT":"2024-02-29","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4962,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.33176,"AVALU":"mg/L","BASE2":10.32273,"BASE":7.1369,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.99097,"PCHG2":-19.28725,"CHG":1.19485,"PCHG":16.74193,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2022-09-26 05:50:09","ADY":594,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-371","SUBJID":"id-371","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.32686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-07","TRTSDTM":"2021-02-09 05:50:09","TRTEDTM":"2024-02-09 23:50:09","TRT01SDTM":"2021-02-09 05:50:09","TRT01EDTM":"2023-02-09 17:50:09","TRT02SDTM":"2023-02-09 17:50:09","TRT02EDTM":"2024-02-09 23:50:09","AP01SDTM":"2021-02-09 05:50:09","AP01EDTM":"2023-02-09 17:50:09","AP02SDTM":"2023-02-09 17:50:09","AP02EDTM":"2024-02-09 23:50:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-09","EOSDY":1096,"LSTALVDT":"2024-02-29","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5064,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.33739,"AVALU":"mg/L","BASE2":10.32273,"BASE":7.1369,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.98533,"PCHG2":-9.54529,"CHG":2.20049,"PCHG":30.83258,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2023-10-27 05:50:09","ADY":990,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-371","SUBJID":"id-371","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.32686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-07","TRTSDTM":"2021-02-09 05:50:09","TRTEDTM":"2024-02-09 23:50:09","TRT01SDTM":"2021-02-09 05:50:09","TRT01EDTM":"2023-02-09 17:50:09","TRT02SDTM":"2023-02-09 17:50:09","TRT02EDTM":"2024-02-09 23:50:09","AP01SDTM":"2021-02-09 05:50:09","AP01EDTM":"2023-02-09 17:50:09","AP02SDTM":"2023-02-09 17:50:09","AP02EDTM":"2024-02-09 23:50:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-09","EOSDY":1096,"LSTALVDT":"2024-02-29","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4910,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86638,"AVALU":"g/L","BASE2":2.86638,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-04-12 05:50:09","ADY":62,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-371","SUBJID":"id-371","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.32686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-07","TRTSDTM":"2021-02-09 05:50:09","TRTEDTM":"2024-02-09 23:50:09","TRT01SDTM":"2021-02-09 05:50:09","TRT01EDTM":"2023-02-09 17:50:09","TRT02SDTM":"2023-02-09 17:50:09","TRT02EDTM":"2024-02-09 23:50:09","AP01SDTM":"2021-02-09 05:50:09","AP01EDTM":"2023-02-09 17:50:09","AP02SDTM":"2023-02-09 17:50:09","AP02EDTM":"2024-02-09 23:50:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-09","EOSDY":1096,"LSTALVDT":"2024-02-29","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5245,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02186,"AVALU":"g/L","BASE2":2.86638,"BASE":3.02186,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.15547,"PCHG2":5.42404,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2021-05-01 05:50:09","ADY":81,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-371","SUBJID":"id-371","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.32686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-07","TRTSDTM":"2021-02-09 05:50:09","TRTEDTM":"2024-02-09 23:50:09","TRT01SDTM":"2021-02-09 05:50:09","TRT01EDTM":"2023-02-09 17:50:09","TRT02SDTM":"2023-02-09 17:50:09","TRT02EDTM":"2024-02-09 23:50:09","AP01SDTM":"2021-02-09 05:50:09","AP01EDTM":"2023-02-09 17:50:09","AP02SDTM":"2023-02-09 17:50:09","AP02EDTM":"2024-02-09 23:50:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-09","EOSDY":1096,"LSTALVDT":"2024-02-29","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5331,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75882,"AVALU":"g/L","BASE2":2.86638,"BASE":3.02186,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10756,"PCHG2":-3.75246,"CHG":-0.26303,"PCHG":-8.70437,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-12-20 05:50:09","ADY":314,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-371","SUBJID":"id-371","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.32686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-07","TRTSDTM":"2021-02-09 05:50:09","TRTEDTM":"2024-02-09 23:50:09","TRT01SDTM":"2021-02-09 05:50:09","TRT01EDTM":"2023-02-09 17:50:09","TRT02SDTM":"2023-02-09 17:50:09","TRT02EDTM":"2024-02-09 23:50:09","AP01SDTM":"2021-02-09 05:50:09","AP01EDTM":"2023-02-09 17:50:09","AP02SDTM":"2023-02-09 17:50:09","AP02EDTM":"2024-02-09 23:50:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-09","EOSDY":1096,"LSTALVDT":"2024-02-29","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":492,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97113,"AVALU":"g/L","BASE2":2.86638,"BASE":3.02186,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10475,"PCHG2":3.65437,"CHG":-0.05073,"PCHG":-1.67862,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2022-07-29 05:50:09","ADY":535,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-371","SUBJID":"id-371","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.32686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-07","TRTSDTM":"2021-02-09 05:50:09","TRTEDTM":"2024-02-09 23:50:09","TRT01SDTM":"2021-02-09 05:50:09","TRT01EDTM":"2023-02-09 17:50:09","TRT02SDTM":"2023-02-09 17:50:09","TRT02EDTM":"2024-02-09 23:50:09","AP01SDTM":"2021-02-09 05:50:09","AP01EDTM":"2023-02-09 17:50:09","AP02SDTM":"2023-02-09 17:50:09","AP02EDTM":"2024-02-09 23:50:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-09","EOSDY":1096,"LSTALVDT":"2024-02-29","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":888,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77481,"AVALU":"g/L","BASE2":2.86638,"BASE":3.02186,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09157,"PCHG2":-3.19454,"CHG":-0.24704,"PCHG":-8.17515,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2022-09-16 05:50:09","ADY":584,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-371","SUBJID":"id-371","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.32686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-07","TRTSDTM":"2021-02-09 05:50:09","TRTEDTM":"2024-02-09 23:50:09","TRT01SDTM":"2021-02-09 05:50:09","TRT01EDTM":"2023-02-09 17:50:09","TRT02SDTM":"2023-02-09 17:50:09","TRT02EDTM":"2024-02-09 23:50:09","AP01SDTM":"2021-02-09 05:50:09","AP01EDTM":"2023-02-09 17:50:09","AP02SDTM":"2023-02-09 17:50:09","AP02EDTM":"2024-02-09 23:50:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-09","EOSDY":1096,"LSTALVDT":"2024-02-29","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6766,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95155,"AVALU":"g/L","BASE2":2.86638,"BASE":3.02186,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08516,"PCHG2":2.97112,"CHG":-0.07031,"PCHG":-2.32672,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2022-09-26 05:50:09","ADY":594,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-371","SUBJID":"id-371","SITEID":"CHN-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.32686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-02-07","TRTSDTM":"2021-02-09 05:50:09","TRTEDTM":"2024-02-09 23:50:09","TRT01SDTM":"2021-02-09 05:50:09","TRT01EDTM":"2023-02-09 17:50:09","TRT02SDTM":"2023-02-09 17:50:09","TRT02EDTM":"2024-02-09 23:50:09","AP01SDTM":"2021-02-09 05:50:09","AP01EDTM":"2023-02-09 17:50:09","AP02SDTM":"2023-02-09 17:50:09","AP02EDTM":"2024-02-09 23:50:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-09","EOSDY":1096,"LSTALVDT":"2024-02-29","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5873,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90653,"AVALU":"g/L","BASE2":2.86638,"BASE":3.02186,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04014,"PCHG2":1.40052,"CHG":-0.11533,"PCHG":-3.81651,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2023-10-27 05:50:09","ADY":990,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-376","SUBJID":"id-376","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":21.39337,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-26","TRTSDTM":"2019-09-30 23:42:56","TRT01SDTM":"2019-09-30 23:42:56","AP01SDTM":"2019-09-30 23:42:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6352,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.64264,"AVALU":"U/L","BASE2":11.64264,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-09 23:42:56","ADY":40,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-376","SUBJID":"id-376","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":21.39337,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-26","TRTSDTM":"2019-09-30 23:42:56","TRT01SDTM":"2019-09-30 23:42:56","AP01SDTM":"2019-09-30 23:42:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1114,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.72725,"AVALU":"U/L","BASE2":11.64264,"BASE":12.72725,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.08461,"PCHG2":9.31585,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-20 23:42:56","ADY":386,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-376","SUBJID":"id-376","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":21.39337,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-26","TRTSDTM":"2019-09-30 23:42:56","TRT01SDTM":"2019-09-30 23:42:56","AP01SDTM":"2019-09-30 23:42:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7799,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.11268,"AVALU":"U/L","BASE2":11.64264,"BASE":12.72725,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.47004,"PCHG2":4.03726,"CHG":-0.61457,"PCHG":-4.82876,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-17 23:42:56","ADY":414,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-376","SUBJID":"id-376","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":21.39337,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-26","TRTSDTM":"2019-09-30 23:42:56","TRT01SDTM":"2019-09-30 23:42:56","AP01SDTM":"2019-09-30 23:42:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4437,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.92789,"AVALU":"U/L","BASE2":11.64264,"BASE":12.72725,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.71475,"PCHG2":-23.31729,"CHG":-3.79936,"PCHG":-29.85216,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-25 23:42:56","ADY":422,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-376","SUBJID":"id-376","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":21.39337,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-26","TRTSDTM":"2019-09-30 23:42:56","TRT01SDTM":"2019-09-30 23:42:56","AP01SDTM":"2019-09-30 23:42:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3475,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":39.23441,"AVALU":"U/L","BASE2":11.64264,"BASE":12.72725,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":27.59177,"PCHG2":236.98907,"CHG":26.50716,"PCHG":208.27101,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-19 23:42:56","ADY":446,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-376","SUBJID":"id-376","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":21.39337,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-26","TRTSDTM":"2019-09-30 23:42:56","TRT01SDTM":"2019-09-30 23:42:56","AP01SDTM":"2019-09-30 23:42:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5819,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.91846,"AVALU":"U/L","BASE2":11.64264,"BASE":12.72725,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.72418,"PCHG2":-49.16564,"CHG":-6.80879,"PCHG":-53.49772,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-02-01 23:42:56","ADY":490,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-376","SUBJID":"id-376","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":21.39337,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-26","TRTSDTM":"2019-09-30 23:42:56","TRT01SDTM":"2019-09-30 23:42:56","AP01SDTM":"2019-09-30 23:42:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2182,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.92097,"AVALU":"U/L","BASE2":11.64264,"BASE":12.72725,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.72166,"PCHG2":-49.14406,"CHG":-6.80627,"PCHG":-53.47799,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-03-10 23:42:56","ADY":527,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-376","SUBJID":"id-376","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":21.39337,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-26","TRTSDTM":"2019-09-30 23:42:56","TRT01SDTM":"2019-09-30 23:42:56","AP01SDTM":"2019-09-30 23:42:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3826,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.86228,"AVALU":"mg/L","BASE2":9.86228,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2019-11-09 23:42:56","ADY":40,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-376","SUBJID":"id-376","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":21.39337,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-26","TRTSDTM":"2019-09-30 23:42:56","TRT01SDTM":"2019-09-30 23:42:56","AP01SDTM":"2019-09-30 23:42:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2687,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.43108,"AVALU":"mg/L","BASE2":9.86228,"BASE":10.43108,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.5688,"PCHG2":5.7674,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-10-20 23:42:56","ADY":386,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-376","SUBJID":"id-376","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":21.39337,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-26","TRTSDTM":"2019-09-30 23:42:56","TRT01SDTM":"2019-09-30 23:42:56","AP01SDTM":"2019-09-30 23:42:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":655,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":12.1499,"AVALU":"mg/L","BASE2":9.86228,"BASE":10.43108,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.28761,"PCHG2":23.19558,"CHG":1.71882,"PCHG":16.47784,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"4","BTOXGR":"1","ADTM":"2020-11-17 23:42:56","ADY":414,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-376","SUBJID":"id-376","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":21.39337,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-26","TRTSDTM":"2019-09-30 23:42:56","TRT01SDTM":"2019-09-30 23:42:56","AP01SDTM":"2019-09-30 23:42:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3464,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.54087,"AVALU":"mg/L","BASE2":9.86228,"BASE":10.43108,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.67858,"PCHG2":17.02024,"CHG":1.10979,"PCHG":10.63924,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"1","ADTM":"2020-11-25 23:42:56","ADY":422,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-376","SUBJID":"id-376","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":21.39337,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-26","TRTSDTM":"2019-09-30 23:42:56","TRT01SDTM":"2019-09-30 23:42:56","AP01SDTM":"2019-09-30 23:42:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6994,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.99086,"AVALU":"mg/L","BASE2":9.86228,"BASE":10.43108,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.87143,"PCHG2":-18.97558,"CHG":-2.44022,"PCHG":-23.39377,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-3","BTOXGR":"1","ADTM":"2020-12-19 23:42:56","ADY":446,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-376","SUBJID":"id-376","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":21.39337,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-26","TRTSDTM":"2019-09-30 23:42:56","TRT01SDTM":"2019-09-30 23:42:56","AP01SDTM":"2019-09-30 23:42:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2761,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.96948,"AVALU":"mg/L","BASE2":9.86228,"BASE":10.43108,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.8928,"PCHG2":-9.05272,"CHG":-1.4616,"PCHG":-14.01199,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-02-01 23:42:56","ADY":490,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-376","SUBJID":"id-376","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":21.39337,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-26","TRTSDTM":"2019-09-30 23:42:56","TRT01SDTM":"2019-09-30 23:42:56","AP01SDTM":"2019-09-30 23:42:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2727,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.77825,"AVALU":"mg/L","BASE2":9.86228,"BASE":10.43108,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.08403,"PCHG2":-10.99165,"CHG":-1.65282,"PCHG":-15.8452,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-03-10 23:42:56","ADY":527,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-376","SUBJID":"id-376","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":21.39337,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-26","TRTSDTM":"2019-09-30 23:42:56","TRT01SDTM":"2019-09-30 23:42:56","AP01SDTM":"2019-09-30 23:42:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8175,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97903,"AVALU":"g/L","BASE2":2.97903,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-09 23:42:56","ADY":40,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-376","SUBJID":"id-376","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":21.39337,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-26","TRTSDTM":"2019-09-30 23:42:56","TRT01SDTM":"2019-09-30 23:42:56","AP01SDTM":"2019-09-30 23:42:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2528,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97512,"AVALU":"g/L","BASE2":2.97903,"BASE":2.97512,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.0039,"PCHG2":-0.13102,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-20 23:42:56","ADY":386,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-376","SUBJID":"id-376","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":21.39337,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-26","TRTSDTM":"2019-09-30 23:42:56","TRT01SDTM":"2019-09-30 23:42:56","AP01SDTM":"2019-09-30 23:42:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1679,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96591,"AVALU":"g/L","BASE2":2.97903,"BASE":2.97512,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01312,"PCHG2":-0.44035,"CHG":-0.00922,"PCHG":-0.30974,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-17 23:42:56","ADY":414,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-376","SUBJID":"id-376","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":21.39337,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-26","TRTSDTM":"2019-09-30 23:42:56","TRT01SDTM":"2019-09-30 23:42:56","AP01SDTM":"2019-09-30 23:42:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":671,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00152,"AVALU":"g/L","BASE2":2.97903,"BASE":2.97512,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02249,"PCHG2":0.75502,"CHG":0.0264,"PCHG":0.8872,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-11-25 23:42:56","ADY":422,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-376","SUBJID":"id-376","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":21.39337,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-26","TRTSDTM":"2019-09-30 23:42:56","TRT01SDTM":"2019-09-30 23:42:56","AP01SDTM":"2019-09-30 23:42:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5945,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77364,"AVALU":"g/L","BASE2":2.97903,"BASE":2.97512,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20538,"PCHG2":-6.89436,"CHG":-0.20148,"PCHG":-6.77222,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-19 23:42:56","ADY":446,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-376","SUBJID":"id-376","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":21.39337,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-26","TRTSDTM":"2019-09-30 23:42:56","TRT01SDTM":"2019-09-30 23:42:56","AP01SDTM":"2019-09-30 23:42:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6979,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.06589,"AVALU":"g/L","BASE2":2.97903,"BASE":2.97512,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08687,"PCHG2":2.91589,"CHG":0.09077,"PCHG":3.0509,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-02-01 23:42:56","ADY":490,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-376","SUBJID":"id-376","SITEID":"CHN-1","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":21.39337,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-26","TRTSDTM":"2019-09-30 23:42:56","TRT01SDTM":"2019-09-30 23:42:56","AP01SDTM":"2019-09-30 23:42:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1875,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91472,"AVALU":"g/L","BASE2":2.97903,"BASE":2.97512,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0643,"PCHG2":-2.15856,"CHG":-0.0604,"PCHG":-2.0302,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-10 23:42:56","ADY":527,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-389","SUBJID":"id-389","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.82133,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-07-02 12:07:49","TRTEDTM":"2023-07-03 06:07:49","TRT01SDTM":"2020-07-02 12:07:49","TRT01EDTM":"2022-07-03 00:07:49","TRT02SDTM":"2022-07-03 00:07:49","TRT02EDTM":"2023-07-03 06:07:49","AP01SDTM":"2020-07-02 12:07:49","AP01EDTM":"2022-07-03 00:07:49","AP02SDTM":"2022-07-03 00:07:49","AP02EDTM":"2023-07-03 06:07:49","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-03","EOSDY":1096,"LSTALVDT":"2023-07-13","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5514,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.56012,"AVALU":"U/L","BASE2":19.56012,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-02 12:07:49","ADY":0,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-389","SUBJID":"id-389","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.82133,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-07-02 12:07:49","TRTEDTM":"2023-07-03 06:07:49","TRT01SDTM":"2020-07-02 12:07:49","TRT01EDTM":"2022-07-03 00:07:49","TRT02SDTM":"2022-07-03 00:07:49","TRT02EDTM":"2023-07-03 06:07:49","AP01SDTM":"2020-07-02 12:07:49","AP01EDTM":"2022-07-03 00:07:49","AP02SDTM":"2022-07-03 00:07:49","AP02EDTM":"2023-07-03 06:07:49","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-03","EOSDY":1096,"LSTALVDT":"2023-07-13","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1750,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.73406,"AVALU":"U/L","BASE2":19.56012,"BASE":27.73406,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":8.17394,"PCHG2":41.78883,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-25 12:07:49","ADY":266,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-389","SUBJID":"id-389","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.82133,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-07-02 12:07:49","TRTEDTM":"2023-07-03 06:07:49","TRT01SDTM":"2020-07-02 12:07:49","TRT01EDTM":"2022-07-03 00:07:49","TRT02SDTM":"2022-07-03 00:07:49","TRT02EDTM":"2023-07-03 06:07:49","AP01SDTM":"2020-07-02 12:07:49","AP01EDTM":"2022-07-03 00:07:49","AP02SDTM":"2022-07-03 00:07:49","AP02EDTM":"2023-07-03 06:07:49","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-03","EOSDY":1096,"LSTALVDT":"2023-07-13","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8304,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.32379,"AVALU":"U/L","BASE2":19.56012,"BASE":27.73406,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.23632,"PCHG2":-36.99529,"CHG":-15.41027,"PCHG":-55.5644,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-18 12:07:49","ADY":290,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-389","SUBJID":"id-389","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.82133,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-07-02 12:07:49","TRTEDTM":"2023-07-03 06:07:49","TRT01SDTM":"2020-07-02 12:07:49","TRT01EDTM":"2022-07-03 00:07:49","TRT02SDTM":"2022-07-03 00:07:49","TRT02EDTM":"2023-07-03 06:07:49","AP01SDTM":"2020-07-02 12:07:49","AP01EDTM":"2022-07-03 00:07:49","AP02SDTM":"2022-07-03 00:07:49","AP02EDTM":"2023-07-03 06:07:49","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-03","EOSDY":1096,"LSTALVDT":"2023-07-13","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7226,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.79893,"AVALU":"U/L","BASE2":19.56012,"BASE":27.73406,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.76118,"PCHG2":-85.69061,"CHG":-24.93513,"PCHG":-89.90796,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-02-07 12:07:49","ADY":585,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-389","SUBJID":"id-389","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.82133,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-07-02 12:07:49","TRTEDTM":"2023-07-03 06:07:49","TRT01SDTM":"2020-07-02 12:07:49","TRT01EDTM":"2022-07-03 00:07:49","TRT02SDTM":"2022-07-03 00:07:49","TRT02EDTM":"2023-07-03 06:07:49","AP01SDTM":"2020-07-02 12:07:49","AP01EDTM":"2022-07-03 00:07:49","AP02SDTM":"2022-07-03 00:07:49","AP02EDTM":"2023-07-03 06:07:49","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-03","EOSDY":1096,"LSTALVDT":"2023-07-13","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3731,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.72796,"AVALU":"U/L","BASE2":19.56012,"BASE":27.73406,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.16785,"PCHG2":5.97054,"CHG":-7.0061,"PCHG":-25.26171,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-31 12:07:49","ADY":698,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-389","SUBJID":"id-389","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.82133,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-07-02 12:07:49","TRTEDTM":"2023-07-03 06:07:49","TRT01SDTM":"2020-07-02 12:07:49","TRT01EDTM":"2022-07-03 00:07:49","TRT02SDTM":"2022-07-03 00:07:49","TRT02EDTM":"2023-07-03 06:07:49","AP01SDTM":"2020-07-02 12:07:49","AP01EDTM":"2022-07-03 00:07:49","AP02SDTM":"2022-07-03 00:07:49","AP02EDTM":"2023-07-03 06:07:49","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-03","EOSDY":1096,"LSTALVDT":"2023-07-13","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8323,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.62726,"AVALU":"U/L","BASE2":19.56012,"BASE":27.73406,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.06714,"PCHG2":51.46769,"CHG":1.8932,"PCHG":6.82626,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-07 12:07:49","ADY":919,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-389","SUBJID":"id-389","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.82133,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-07-02 12:07:49","TRTEDTM":"2023-07-03 06:07:49","TRT01SDTM":"2020-07-02 12:07:49","TRT01EDTM":"2022-07-03 00:07:49","TRT02SDTM":"2022-07-03 00:07:49","TRT02EDTM":"2023-07-03 06:07:49","AP01SDTM":"2020-07-02 12:07:49","AP01EDTM":"2022-07-03 00:07:49","AP02SDTM":"2022-07-03 00:07:49","AP02EDTM":"2023-07-03 06:07:49","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-03","EOSDY":1096,"LSTALVDT":"2023-07-13","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4914,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.34105,"AVALU":"U/L","BASE2":19.56012,"BASE":27.73406,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.78094,"PCHG2":65.34182,"CHG":4.60699,"PCHG":16.61132,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-21 12:07:49","ADY":1053,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-389","SUBJID":"id-389","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.82133,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-07-02 12:07:49","TRTEDTM":"2023-07-03 06:07:49","TRT01SDTM":"2020-07-02 12:07:49","TRT01EDTM":"2022-07-03 00:07:49","TRT02SDTM":"2022-07-03 00:07:49","TRT02EDTM":"2023-07-03 06:07:49","AP01SDTM":"2020-07-02 12:07:49","AP01EDTM":"2022-07-03 00:07:49","AP02SDTM":"2022-07-03 00:07:49","AP02EDTM":"2023-07-03 06:07:49","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-03","EOSDY":1096,"LSTALVDT":"2023-07-13","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4483,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.50671,"AVALU":"mg/L","BASE2":9.50671,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-07-02 12:07:49","ADY":0,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-389","SUBJID":"id-389","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.82133,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-07-02 12:07:49","TRTEDTM":"2023-07-03 06:07:49","TRT01SDTM":"2020-07-02 12:07:49","TRT01EDTM":"2022-07-03 00:07:49","TRT02SDTM":"2022-07-03 00:07:49","TRT02EDTM":"2023-07-03 06:07:49","AP01SDTM":"2020-07-02 12:07:49","AP01EDTM":"2022-07-03 00:07:49","AP02SDTM":"2022-07-03 00:07:49","AP02EDTM":"2023-07-03 06:07:49","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-03","EOSDY":1096,"LSTALVDT":"2023-07-13","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4436,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.22428,"AVALU":"mg/L","BASE2":9.50671,"BASE":7.22428,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.28243,"PCHG2":-24.00865,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2021-03-25 12:07:49","ADY":266,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-389","SUBJID":"id-389","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.82133,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-07-02 12:07:49","TRTEDTM":"2023-07-03 06:07:49","TRT01SDTM":"2020-07-02 12:07:49","TRT01EDTM":"2022-07-03 00:07:49","TRT02SDTM":"2022-07-03 00:07:49","TRT02EDTM":"2023-07-03 06:07:49","AP01SDTM":"2020-07-02 12:07:49","AP01EDTM":"2022-07-03 00:07:49","AP02SDTM":"2022-07-03 00:07:49","AP02EDTM":"2023-07-03 06:07:49","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-03","EOSDY":1096,"LSTALVDT":"2023-07-13","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1818,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.65516,"AVALU":"mg/L","BASE2":9.50671,"BASE":7.22428,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.85156,"PCHG2":-8.95741,"CHG":1.43088,"PCHG":19.80652,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-04-18 12:07:49","ADY":290,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-389","SUBJID":"id-389","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.82133,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-07-02 12:07:49","TRTEDTM":"2023-07-03 06:07:49","TRT01SDTM":"2020-07-02 12:07:49","TRT01EDTM":"2022-07-03 00:07:49","TRT02SDTM":"2022-07-03 00:07:49","TRT02EDTM":"2023-07-03 06:07:49","AP01SDTM":"2020-07-02 12:07:49","AP01EDTM":"2022-07-03 00:07:49","AP02SDTM":"2022-07-03 00:07:49","AP02EDTM":"2023-07-03 06:07:49","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-03","EOSDY":1096,"LSTALVDT":"2023-07-13","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6740,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.376,"AVALU":"mg/L","BASE2":9.50671,"BASE":7.22428,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.86929,"PCHG2":9.14392,"CHG":3.15172,"PCHG":43.62677,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"1","BTOXGR":"-1","ADTM":"2022-02-07 12:07:49","ADY":585,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-389","SUBJID":"id-389","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.82133,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-07-02 12:07:49","TRTEDTM":"2023-07-03 06:07:49","TRT01SDTM":"2020-07-02 12:07:49","TRT01EDTM":"2022-07-03 00:07:49","TRT02SDTM":"2022-07-03 00:07:49","TRT02EDTM":"2023-07-03 06:07:49","AP01SDTM":"2020-07-02 12:07:49","AP01EDTM":"2022-07-03 00:07:49","AP02SDTM":"2022-07-03 00:07:49","AP02EDTM":"2023-07-03 06:07:49","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-03","EOSDY":1096,"LSTALVDT":"2023-07-13","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1291,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.35802,"AVALU":"mg/L","BASE2":9.50671,"BASE":7.22428,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1487,"PCHG2":-1.56411,"CHG":2.13374,"PCHG":29.53565,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-05-31 12:07:49","ADY":698,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-389","SUBJID":"id-389","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.82133,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-07-02 12:07:49","TRTEDTM":"2023-07-03 06:07:49","TRT01SDTM":"2020-07-02 12:07:49","TRT01EDTM":"2022-07-03 00:07:49","TRT02SDTM":"2022-07-03 00:07:49","TRT02EDTM":"2023-07-03 06:07:49","AP01SDTM":"2020-07-02 12:07:49","AP01EDTM":"2022-07-03 00:07:49","AP02SDTM":"2022-07-03 00:07:49","AP02EDTM":"2023-07-03 06:07:49","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-03","EOSDY":1096,"LSTALVDT":"2023-07-13","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1784,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.9212,"AVALU":"mg/L","BASE2":9.50671,"BASE":7.22428,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.58551,"PCHG2":-16.67779,"CHG":0.69692,"PCHG":9.64696,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-4","BTOXGR":"-1","ADTM":"2023-01-07 12:07:49","ADY":919,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-389","SUBJID":"id-389","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.82133,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-07-02 12:07:49","TRTEDTM":"2023-07-03 06:07:49","TRT01SDTM":"2020-07-02 12:07:49","TRT01EDTM":"2022-07-03 00:07:49","TRT02SDTM":"2022-07-03 00:07:49","TRT02EDTM":"2023-07-03 06:07:49","AP01SDTM":"2020-07-02 12:07:49","AP01EDTM":"2022-07-03 00:07:49","AP02SDTM":"2022-07-03 00:07:49","AP02EDTM":"2023-07-03 06:07:49","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-03","EOSDY":1096,"LSTALVDT":"2023-07-13","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4767,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.95518,"AVALU":"mg/L","BASE2":9.50671,"BASE":7.22428,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.55153,"PCHG2":-16.32034,"CHG":0.73091,"PCHG":10.11735,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-3","BTOXGR":"-1","ADTM":"2023-05-21 12:07:49","ADY":1053,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-389","SUBJID":"id-389","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.82133,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-07-02 12:07:49","TRTEDTM":"2023-07-03 06:07:49","TRT01SDTM":"2020-07-02 12:07:49","TRT01EDTM":"2022-07-03 00:07:49","TRT02SDTM":"2022-07-03 00:07:49","TRT02EDTM":"2023-07-03 06:07:49","AP01SDTM":"2020-07-02 12:07:49","AP01EDTM":"2022-07-03 00:07:49","AP02SDTM":"2022-07-03 00:07:49","AP02EDTM":"2023-07-03 06:07:49","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-03","EOSDY":1096,"LSTALVDT":"2023-07-13","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6166,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81617,"AVALU":"g/L","BASE2":2.81617,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-02 12:07:49","ADY":0,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-389","SUBJID":"id-389","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.82133,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-07-02 12:07:49","TRTEDTM":"2023-07-03 06:07:49","TRT01SDTM":"2020-07-02 12:07:49","TRT01EDTM":"2022-07-03 00:07:49","TRT02SDTM":"2022-07-03 00:07:49","TRT02EDTM":"2023-07-03 06:07:49","AP01SDTM":"2020-07-02 12:07:49","AP01EDTM":"2022-07-03 00:07:49","AP02SDTM":"2022-07-03 00:07:49","AP02EDTM":"2023-07-03 06:07:49","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-03","EOSDY":1096,"LSTALVDT":"2023-07-13","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7277,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91262,"AVALU":"g/L","BASE2":2.81617,"BASE":2.91262,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.09645,"PCHG2":3.42491,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-25 12:07:49","ADY":266,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-389","SUBJID":"id-389","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.82133,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-07-02 12:07:49","TRTEDTM":"2023-07-03 06:07:49","TRT01SDTM":"2020-07-02 12:07:49","TRT01EDTM":"2022-07-03 00:07:49","TRT02SDTM":"2022-07-03 00:07:49","TRT02EDTM":"2023-07-03 06:07:49","AP01SDTM":"2020-07-02 12:07:49","AP01EDTM":"2022-07-03 00:07:49","AP02SDTM":"2022-07-03 00:07:49","AP02EDTM":"2023-07-03 06:07:49","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-03","EOSDY":1096,"LSTALVDT":"2023-07-13","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2837,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89458,"AVALU":"g/L","BASE2":2.81617,"BASE":2.91262,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07841,"PCHG2":2.78427,"CHG":-0.01804,"PCHG":-0.61942,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-18 12:07:49","ADY":290,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-389","SUBJID":"id-389","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.82133,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-07-02 12:07:49","TRTEDTM":"2023-07-03 06:07:49","TRT01SDTM":"2020-07-02 12:07:49","TRT01EDTM":"2022-07-03 00:07:49","TRT02SDTM":"2022-07-03 00:07:49","TRT02EDTM":"2023-07-03 06:07:49","AP01SDTM":"2020-07-02 12:07:49","AP01EDTM":"2022-07-03 00:07:49","AP02SDTM":"2022-07-03 00:07:49","AP02EDTM":"2023-07-03 06:07:49","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-03","EOSDY":1096,"LSTALVDT":"2023-07-13","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7495,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91879,"AVALU":"g/L","BASE2":2.81617,"BASE":2.91262,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10262,"PCHG2":3.64402,"CHG":0.00617,"PCHG":0.21186,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-07 12:07:49","ADY":585,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-389","SUBJID":"id-389","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.82133,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-07-02 12:07:49","TRTEDTM":"2023-07-03 06:07:49","TRT01SDTM":"2020-07-02 12:07:49","TRT01EDTM":"2022-07-03 00:07:49","TRT02SDTM":"2022-07-03 00:07:49","TRT02EDTM":"2023-07-03 06:07:49","AP01SDTM":"2020-07-02 12:07:49","AP01EDTM":"2022-07-03 00:07:49","AP02SDTM":"2022-07-03 00:07:49","AP02EDTM":"2023-07-03 06:07:49","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-03","EOSDY":1096,"LSTALVDT":"2023-07-13","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3712,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.70583,"AVALU":"g/L","BASE2":2.81617,"BASE":2.91262,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11034,"PCHG2":-3.91809,"CHG":-0.20679,"PCHG":-7.09983,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-31 12:07:49","ADY":698,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-389","SUBJID":"id-389","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.82133,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-07-02 12:07:49","TRTEDTM":"2023-07-03 06:07:49","TRT01SDTM":"2020-07-02 12:07:49","TRT01EDTM":"2022-07-03 00:07:49","TRT02SDTM":"2022-07-03 00:07:49","TRT02EDTM":"2023-07-03 06:07:49","AP01SDTM":"2020-07-02 12:07:49","AP01EDTM":"2022-07-03 00:07:49","AP02SDTM":"2022-07-03 00:07:49","AP02EDTM":"2023-07-03 06:07:49","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-03","EOSDY":1096,"LSTALVDT":"2023-07-13","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4847,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77261,"AVALU":"g/L","BASE2":2.81617,"BASE":2.91262,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04356,"PCHG2":-1.54674,"CHG":-0.14001,"PCHG":-4.80701,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-07 12:07:49","ADY":919,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-389","SUBJID":"id-389","SITEID":"CHN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.82133,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-07-02 12:07:49","TRTEDTM":"2023-07-03 06:07:49","TRT01SDTM":"2020-07-02 12:07:49","TRT01EDTM":"2022-07-03 00:07:49","TRT02SDTM":"2022-07-03 00:07:49","TRT02EDTM":"2023-07-03 06:07:49","AP01SDTM":"2020-07-02 12:07:49","AP01EDTM":"2022-07-03 00:07:49","AP02SDTM":"2022-07-03 00:07:49","AP02EDTM":"2023-07-03 06:07:49","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-03","EOSDY":1096,"LSTALVDT":"2023-07-13","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2394,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94302,"AVALU":"g/L","BASE2":2.81617,"BASE":2.91262,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12685,"PCHG2":4.50449,"CHG":0.0304,"PCHG":1.04384,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-21 12:07:49","ADY":1053,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-400","SUBJID":"id-400","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.77615,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-16 18:27:24","TRTEDTM":"2022-09-16 12:27:24","TRT01SDTM":"2019-09-16 18:27:24","TRT01EDTM":"2021-09-16 06:27:24","TRT02SDTM":"2021-09-16 06:27:24","TRT02EDTM":"2022-09-16 12:27:24","AP01SDTM":"2019-09-16 18:27:24","AP01EDTM":"2021-09-16 06:27:24","AP02SDTM":"2021-09-16 06:27:24","AP02EDTM":"2022-09-16 12:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-16","EOSDY":1096,"LSTALVDT":"2022-09-30","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2032,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.26599,"AVALU":"U/L","BASE2":13.26599,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-28 18:27:24","ADY":286,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-400","SUBJID":"id-400","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.77615,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-16 18:27:24","TRTEDTM":"2022-09-16 12:27:24","TRT01SDTM":"2019-09-16 18:27:24","TRT01EDTM":"2021-09-16 06:27:24","TRT02SDTM":"2021-09-16 06:27:24","TRT02EDTM":"2022-09-16 12:27:24","AP01SDTM":"2019-09-16 18:27:24","AP01EDTM":"2021-09-16 06:27:24","AP02SDTM":"2021-09-16 06:27:24","AP02EDTM":"2022-09-16 12:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-16","EOSDY":1096,"LSTALVDT":"2022-09-30","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8162,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.35283,"AVALU":"U/L","BASE2":13.26599,"BASE":24.35283,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":11.08684,"PCHG2":83.57337,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-22 18:27:24","ADY":310,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-400","SUBJID":"id-400","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.77615,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-16 18:27:24","TRTEDTM":"2022-09-16 12:27:24","TRT01SDTM":"2019-09-16 18:27:24","TRT01EDTM":"2021-09-16 06:27:24","TRT02SDTM":"2021-09-16 06:27:24","TRT02EDTM":"2022-09-16 12:27:24","AP01SDTM":"2019-09-16 18:27:24","AP01EDTM":"2021-09-16 06:27:24","AP02SDTM":"2021-09-16 06:27:24","AP02EDTM":"2022-09-16 12:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-16","EOSDY":1096,"LSTALVDT":"2022-09-30","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5698,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.67513,"AVALU":"U/L","BASE2":13.26599,"BASE":24.35283,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.59087,"PCHG2":-64.75855,"CHG":-19.6777,"PCHG":-80.80253,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-11-05 18:27:24","ADY":416,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-400","SUBJID":"id-400","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.77615,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-16 18:27:24","TRTEDTM":"2022-09-16 12:27:24","TRT01SDTM":"2019-09-16 18:27:24","TRT01EDTM":"2021-09-16 06:27:24","TRT02SDTM":"2021-09-16 06:27:24","TRT02EDTM":"2022-09-16 12:27:24","AP01SDTM":"2019-09-16 18:27:24","AP01EDTM":"2021-09-16 06:27:24","AP02SDTM":"2021-09-16 06:27:24","AP02EDTM":"2022-09-16 12:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-16","EOSDY":1096,"LSTALVDT":"2022-09-30","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7054,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.72255,"AVALU":"U/L","BASE2":13.26599,"BASE":24.35283,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.54345,"PCHG2":-11.63461,"CHG":-12.63028,"PCHG":-51.86372,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-11 18:27:24","ADY":634,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-400","SUBJID":"id-400","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.77615,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-16 18:27:24","TRTEDTM":"2022-09-16 12:27:24","TRT01SDTM":"2019-09-16 18:27:24","TRT01EDTM":"2021-09-16 06:27:24","TRT02SDTM":"2021-09-16 06:27:24","TRT02EDTM":"2022-09-16 12:27:24","AP01SDTM":"2019-09-16 18:27:24","AP01EDTM":"2021-09-16 06:27:24","AP02SDTM":"2021-09-16 06:27:24","AP02EDTM":"2022-09-16 12:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-16","EOSDY":1096,"LSTALVDT":"2022-09-30","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4621,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.5838,"AVALU":"U/L","BASE2":13.26599,"BASE":24.35283,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.31781,"PCHG2":17.47182,"CHG":-8.76903,"PCHG":-36.00825,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-17 18:27:24","ADY":701,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-400","SUBJID":"id-400","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.77615,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-16 18:27:24","TRTEDTM":"2022-09-16 12:27:24","TRT01SDTM":"2019-09-16 18:27:24","TRT01EDTM":"2021-09-16 06:27:24","TRT02SDTM":"2021-09-16 06:27:24","TRT02EDTM":"2022-09-16 12:27:24","AP01SDTM":"2019-09-16 18:27:24","AP01EDTM":"2021-09-16 06:27:24","AP02SDTM":"2021-09-16 06:27:24","AP02EDTM":"2022-09-16 12:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-16","EOSDY":1096,"LSTALVDT":"2022-09-30","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5658,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.13326,"AVALU":"U/L","BASE2":13.26599,"BASE":24.35283,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.86727,"PCHG2":14.07559,"CHG":-9.21957,"PCHG":-37.85831,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-11 18:27:24","ADY":817,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-400","SUBJID":"id-400","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.77615,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-16 18:27:24","TRTEDTM":"2022-09-16 12:27:24","TRT01SDTM":"2019-09-16 18:27:24","TRT01EDTM":"2021-09-16 06:27:24","TRT02SDTM":"2021-09-16 06:27:24","TRT02EDTM":"2022-09-16 12:27:24","AP01SDTM":"2019-09-16 18:27:24","AP01EDTM":"2021-09-16 06:27:24","AP02SDTM":"2021-09-16 06:27:24","AP02EDTM":"2022-09-16 12:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-16","EOSDY":1096,"LSTALVDT":"2022-09-30","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4476,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.51677,"AVALU":"U/L","BASE2":13.26599,"BASE":24.35283,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.25078,"PCHG2":54.65688,"CHG":-3.83606,"PCHG":-15.75201,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-21 18:27:24","ADY":1009,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-400","SUBJID":"id-400","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.77615,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-16 18:27:24","TRTEDTM":"2022-09-16 12:27:24","TRT01SDTM":"2019-09-16 18:27:24","TRT01EDTM":"2021-09-16 06:27:24","TRT02SDTM":"2021-09-16 06:27:24","TRT02EDTM":"2022-09-16 12:27:24","AP01SDTM":"2019-09-16 18:27:24","AP01EDTM":"2021-09-16 06:27:24","AP02SDTM":"2021-09-16 06:27:24","AP02EDTM":"2022-09-16 12:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-16","EOSDY":1096,"LSTALVDT":"2022-09-30","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2038,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.36125,"AVALU":"mg/L","BASE2":7.36125,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-06-28 18:27:24","ADY":286,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-400","SUBJID":"id-400","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.77615,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-16 18:27:24","TRTEDTM":"2022-09-16 12:27:24","TRT01SDTM":"2019-09-16 18:27:24","TRT01EDTM":"2021-09-16 06:27:24","TRT02SDTM":"2021-09-16 06:27:24","TRT02EDTM":"2022-09-16 12:27:24","AP01SDTM":"2019-09-16 18:27:24","AP01EDTM":"2021-09-16 06:27:24","AP02SDTM":"2021-09-16 06:27:24","AP02EDTM":"2022-09-16 12:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-16","EOSDY":1096,"LSTALVDT":"2022-09-30","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5569,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.75106,"AVALU":"mg/L","BASE2":7.36125,"BASE":8.75106,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.38981,"PCHG2":18.88014,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-22 18:27:24","ADY":310,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-400","SUBJID":"id-400","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.77615,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-16 18:27:24","TRTEDTM":"2022-09-16 12:27:24","TRT01SDTM":"2019-09-16 18:27:24","TRT01EDTM":"2021-09-16 06:27:24","TRT02SDTM":"2021-09-16 06:27:24","TRT02EDTM":"2022-09-16 12:27:24","AP01SDTM":"2019-09-16 18:27:24","AP01EDTM":"2021-09-16 06:27:24","AP02SDTM":"2021-09-16 06:27:24","AP02EDTM":"2022-09-16 12:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-16","EOSDY":1096,"LSTALVDT":"2022-09-30","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6338,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.82099,"AVALU":"mg/L","BASE2":7.36125,"BASE":8.75106,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.45974,"PCHG2":19.83013,"CHG":0.06993,"PCHG":0.79911,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-05 18:27:24","ADY":416,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-400","SUBJID":"id-400","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.77615,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-16 18:27:24","TRTEDTM":"2022-09-16 12:27:24","TRT01SDTM":"2019-09-16 18:27:24","TRT01EDTM":"2021-09-16 06:27:24","TRT02SDTM":"2021-09-16 06:27:24","TRT02EDTM":"2022-09-16 12:27:24","AP01SDTM":"2019-09-16 18:27:24","AP01EDTM":"2021-09-16 06:27:24","AP02SDTM":"2021-09-16 06:27:24","AP02EDTM":"2022-09-16 12:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-16","EOSDY":1096,"LSTALVDT":"2022-09-30","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":557,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.25443,"AVALU":"mg/L","BASE2":7.36125,"BASE":8.75106,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10681,"PCHG2":-1.45102,"CHG":-1.49663,"PCHG":-17.10224,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-06-11 18:27:24","ADY":634,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-400","SUBJID":"id-400","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.77615,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-16 18:27:24","TRTEDTM":"2022-09-16 12:27:24","TRT01SDTM":"2019-09-16 18:27:24","TRT01EDTM":"2021-09-16 06:27:24","TRT02SDTM":"2021-09-16 06:27:24","TRT02EDTM":"2022-09-16 12:27:24","AP01SDTM":"2019-09-16 18:27:24","AP01EDTM":"2021-09-16 06:27:24","AP02SDTM":"2021-09-16 06:27:24","AP02EDTM":"2022-09-16 12:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-16","EOSDY":1096,"LSTALVDT":"2022-09-30","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2882,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.28723,"AVALU":"mg/L","BASE2":7.36125,"BASE":8.75106,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.92598,"PCHG2":39.74849,"CHG":1.53617,"PCHG":17.55411,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-08-17 18:27:24","ADY":701,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-400","SUBJID":"id-400","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.77615,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-16 18:27:24","TRTEDTM":"2022-09-16 12:27:24","TRT01SDTM":"2019-09-16 18:27:24","TRT01EDTM":"2021-09-16 06:27:24","TRT02SDTM":"2021-09-16 06:27:24","TRT02EDTM":"2022-09-16 12:27:24","AP01SDTM":"2019-09-16 18:27:24","AP01EDTM":"2021-09-16 06:27:24","AP02SDTM":"2021-09-16 06:27:24","AP02EDTM":"2022-09-16 12:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-16","EOSDY":1096,"LSTALVDT":"2022-09-30","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":185,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.83035,"AVALU":"mg/L","BASE2":7.36125,"BASE":8.75106,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.4691,"PCHG2":19.95722,"CHG":0.07929,"PCHG":0.90602,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-11 18:27:24","ADY":817,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-400","SUBJID":"id-400","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.77615,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-16 18:27:24","TRTEDTM":"2022-09-16 12:27:24","TRT01SDTM":"2019-09-16 18:27:24","TRT01EDTM":"2021-09-16 06:27:24","TRT02SDTM":"2021-09-16 06:27:24","TRT02EDTM":"2022-09-16 12:27:24","AP01SDTM":"2019-09-16 18:27:24","AP01EDTM":"2021-09-16 06:27:24","AP02SDTM":"2021-09-16 06:27:24","AP02EDTM":"2022-09-16 12:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-16","EOSDY":1096,"LSTALVDT":"2022-09-30","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2541,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.9119,"AVALU":"mg/L","BASE2":7.36125,"BASE":8.75106,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.55065,"PCHG2":7.48046,"CHG":-0.83916,"PCHG":-9.58922,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-06-21 18:27:24","ADY":1009,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-400","SUBJID":"id-400","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.77615,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-16 18:27:24","TRTEDTM":"2022-09-16 12:27:24","TRT01SDTM":"2019-09-16 18:27:24","TRT01EDTM":"2021-09-16 06:27:24","TRT02SDTM":"2021-09-16 06:27:24","TRT02EDTM":"2022-09-16 12:27:24","AP01SDTM":"2019-09-16 18:27:24","AP01EDTM":"2021-09-16 06:27:24","AP02SDTM":"2021-09-16 06:27:24","AP02EDTM":"2022-09-16 12:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-16","EOSDY":1096,"LSTALVDT":"2022-09-30","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4647,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94174,"AVALU":"g/L","BASE2":2.94174,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"2","ADTM":"2020-06-28 18:27:24","ADY":286,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-400","SUBJID":"id-400","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.77615,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-16 18:27:24","TRTEDTM":"2022-09-16 12:27:24","TRT01SDTM":"2019-09-16 18:27:24","TRT01EDTM":"2021-09-16 06:27:24","TRT02SDTM":"2021-09-16 06:27:24","TRT02EDTM":"2022-09-16 12:27:24","AP01SDTM":"2019-09-16 18:27:24","AP01EDTM":"2021-09-16 06:27:24","AP02SDTM":"2021-09-16 06:27:24","AP02EDTM":"2022-09-16 12:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-16","EOSDY":1096,"LSTALVDT":"2022-09-30","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8262,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00473,"AVALU":"g/L","BASE2":2.94174,"BASE":3.00473,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.063,"PCHG2":2.14156,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2020-07-22 18:27:24","ADY":310,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-400","SUBJID":"id-400","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.77615,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-16 18:27:24","TRTEDTM":"2022-09-16 12:27:24","TRT01SDTM":"2019-09-16 18:27:24","TRT01EDTM":"2021-09-16 06:27:24","TRT02SDTM":"2021-09-16 06:27:24","TRT02EDTM":"2022-09-16 12:27:24","AP01SDTM":"2019-09-16 18:27:24","AP01EDTM":"2021-09-16 06:27:24","AP02SDTM":"2021-09-16 06:27:24","AP02EDTM":"2022-09-16 12:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-16","EOSDY":1096,"LSTALVDT":"2022-09-30","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3997,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9988,"AVALU":"g/L","BASE2":2.94174,"BASE":3.00473,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05706,"PCHG2":1.93984,"CHG":-0.00593,"PCHG":-0.19749,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2020-11-05 18:27:24","ADY":416,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-400","SUBJID":"id-400","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.77615,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-16 18:27:24","TRTEDTM":"2022-09-16 12:27:24","TRT01SDTM":"2019-09-16 18:27:24","TRT01EDTM":"2021-09-16 06:27:24","TRT02SDTM":"2021-09-16 06:27:24","TRT02EDTM":"2022-09-16 12:27:24","AP01SDTM":"2019-09-16 18:27:24","AP01EDTM":"2021-09-16 06:27:24","AP02SDTM":"2021-09-16 06:27:24","AP02EDTM":"2022-09-16 12:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-16","EOSDY":1096,"LSTALVDT":"2022-09-30","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7705,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87779,"AVALU":"g/L","BASE2":2.94174,"BASE":3.00473,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06395,"PCHG2":-2.17378,"CHG":-0.12695,"PCHG":-4.22487,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-06-11 18:27:24","ADY":634,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-400","SUBJID":"id-400","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.77615,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-16 18:27:24","TRTEDTM":"2022-09-16 12:27:24","TRT01SDTM":"2019-09-16 18:27:24","TRT01EDTM":"2021-09-16 06:27:24","TRT02SDTM":"2021-09-16 06:27:24","TRT02EDTM":"2022-09-16 12:27:24","AP01SDTM":"2019-09-16 18:27:24","AP01EDTM":"2021-09-16 06:27:24","AP02SDTM":"2021-09-16 06:27:24","AP02EDTM":"2022-09-16 12:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-16","EOSDY":1096,"LSTALVDT":"2022-09-30","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1668,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95847,"AVALU":"g/L","BASE2":2.94174,"BASE":3.00473,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01674,"PCHG2":0.56893,"CHG":-0.04626,"PCHG":-1.53966,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-08-17 18:27:24","ADY":701,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-400","SUBJID":"id-400","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.77615,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-16 18:27:24","TRTEDTM":"2022-09-16 12:27:24","TRT01SDTM":"2019-09-16 18:27:24","TRT01EDTM":"2021-09-16 06:27:24","TRT02SDTM":"2021-09-16 06:27:24","TRT02EDTM":"2022-09-16 12:27:24","AP01SDTM":"2019-09-16 18:27:24","AP01EDTM":"2021-09-16 06:27:24","AP02SDTM":"2021-09-16 06:27:24","AP02EDTM":"2022-09-16 12:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-16","EOSDY":1096,"LSTALVDT":"2022-09-30","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8240,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99618,"AVALU":"g/L","BASE2":2.94174,"BASE":3.00473,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05444,"PCHG2":1.85068,"CHG":-0.00856,"PCHG":-0.28479,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-12-11 18:27:24","ADY":817,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-400","SUBJID":"id-400","SITEID":"CHN-1","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.77615,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-16 18:27:24","TRTEDTM":"2022-09-16 12:27:24","TRT01SDTM":"2019-09-16 18:27:24","TRT01EDTM":"2021-09-16 06:27:24","TRT02SDTM":"2021-09-16 06:27:24","TRT02EDTM":"2022-09-16 12:27:24","AP01SDTM":"2019-09-16 18:27:24","AP01EDTM":"2021-09-16 06:27:24","AP02SDTM":"2021-09-16 06:27:24","AP02EDTM":"2022-09-16 12:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-16","EOSDY":1096,"LSTALVDT":"2022-09-30","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1073,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7485,"AVALU":"g/L","BASE2":2.94174,"BASE":3.00473,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19324,"PCHG2":-6.56881,"CHG":-0.25624,"PCHG":-8.52775,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-06-21 18:27:24","ADY":1009,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-47","SUBJID":"id-47","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.39866,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 04:58:38","TRTEDTM":"2022-02-17 04:06:46","TRT01SDTM":"2020-01-19 04:58:38","TRT01EDTM":"2021-02-16 22:06:46","TRT02SDTM":"2021-02-16 22:06:46","TRT02EDTM":"2022-02-17 04:06:46","AP01SDTM":"2020-01-19 04:58:38","AP01EDTM":"2021-02-16 22:06:46","AP02SDTM":"2021-02-16 22:06:46","AP02EDTM":"2022-02-17 04:06:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":760,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-01","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6538,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.21023,"AVALU":"U/L","BASE2":23.21023,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-06 04:58:38","ADY":18,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-47","SUBJID":"id-47","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.39866,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 04:58:38","TRTEDTM":"2022-02-17 04:06:46","TRT01SDTM":"2020-01-19 04:58:38","TRT01EDTM":"2021-02-16 22:06:46","TRT02SDTM":"2021-02-16 22:06:46","TRT02EDTM":"2022-02-17 04:06:46","AP01SDTM":"2020-01-19 04:58:38","AP01EDTM":"2021-02-16 22:06:46","AP02SDTM":"2021-02-16 22:06:46","AP02EDTM":"2022-02-17 04:06:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":760,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-01","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":154,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.76078,"AVALU":"U/L","BASE2":23.21023,"BASE":23.76078,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.55055,"PCHG2":2.37201,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-19 04:58:38","ADY":152,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-47","SUBJID":"id-47","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.39866,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 04:58:38","TRTEDTM":"2022-02-17 04:06:46","TRT01SDTM":"2020-01-19 04:58:38","TRT01EDTM":"2021-02-16 22:06:46","TRT02SDTM":"2021-02-16 22:06:46","TRT02EDTM":"2022-02-17 04:06:46","AP01SDTM":"2020-01-19 04:58:38","AP01EDTM":"2021-02-16 22:06:46","AP02SDTM":"2021-02-16 22:06:46","AP02EDTM":"2022-02-17 04:06:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":760,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-01","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3652,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.42931,"AVALU":"U/L","BASE2":23.21023,"BASE":23.76078,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-18.78092,"PCHG2":-80.91655,"CHG":-19.33146,"PCHG":-81.35872,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-09-11 04:58:38","ADY":236,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-47","SUBJID":"id-47","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.39866,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 04:58:38","TRTEDTM":"2022-02-17 04:06:46","TRT01SDTM":"2020-01-19 04:58:38","TRT01EDTM":"2021-02-16 22:06:46","TRT02SDTM":"2021-02-16 22:06:46","TRT02EDTM":"2022-02-17 04:06:46","AP01SDTM":"2020-01-19 04:58:38","AP01EDTM":"2021-02-16 22:06:46","AP02SDTM":"2021-02-16 22:06:46","AP02EDTM":"2022-02-17 04:06:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":760,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-01","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4860,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.82587,"AVALU":"U/L","BASE2":23.21023,"BASE":23.76078,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.61564,"PCHG2":11.26935,"CHG":2.06509,"PCHG":8.69119,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-27 04:58:38","ADY":464,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-47","SUBJID":"id-47","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.39866,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 04:58:38","TRTEDTM":"2022-02-17 04:06:46","TRT01SDTM":"2020-01-19 04:58:38","TRT01EDTM":"2021-02-16 22:06:46","TRT02SDTM":"2021-02-16 22:06:46","TRT02EDTM":"2022-02-17 04:06:46","AP01SDTM":"2020-01-19 04:58:38","AP01EDTM":"2021-02-16 22:06:46","AP02SDTM":"2021-02-16 22:06:46","AP02EDTM":"2022-02-17 04:06:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":760,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-01","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7453,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.382,"AVALU":"U/L","BASE2":23.21023,"BASE":23.76078,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17178,"PCHG2":0.74009,"CHG":-0.37877,"PCHG":-1.5941,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-23 04:58:38","ADY":551,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-47","SUBJID":"id-47","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.39866,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 04:58:38","TRTEDTM":"2022-02-17 04:06:46","TRT01SDTM":"2020-01-19 04:58:38","TRT01EDTM":"2021-02-16 22:06:46","TRT02SDTM":"2021-02-16 22:06:46","TRT02EDTM":"2022-02-17 04:06:46","AP01SDTM":"2020-01-19 04:58:38","AP01EDTM":"2021-02-16 22:06:46","AP02SDTM":"2021-02-16 22:06:46","AP02EDTM":"2022-02-17 04:06:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":760,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-01","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8383,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.29858,"AVALU":"U/L","BASE2":23.21023,"BASE":23.76078,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.91165,"PCHG2":-29.77845,"CHG":-7.46219,"PCHG":-31.40552,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-25 04:58:38","ADY":615,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-47","SUBJID":"id-47","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.39866,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 04:58:38","TRTEDTM":"2022-02-17 04:06:46","TRT01SDTM":"2020-01-19 04:58:38","TRT01EDTM":"2021-02-16 22:06:46","TRT02SDTM":"2021-02-16 22:06:46","TRT02EDTM":"2022-02-17 04:06:46","AP01SDTM":"2020-01-19 04:58:38","AP01EDTM":"2021-02-16 22:06:46","AP02SDTM":"2021-02-16 22:06:46","AP02EDTM":"2022-02-17 04:06:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":760,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-01","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3576,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.88845,"AVALU":"U/L","BASE2":23.21023,"BASE":23.76078,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.32177,"PCHG2":-40.16235,"CHG":-9.87232,"PCHG":-41.54881,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-07 04:58:38","ADY":627,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-47","SUBJID":"id-47","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.39866,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 04:58:38","TRTEDTM":"2022-02-17 04:06:46","TRT01SDTM":"2020-01-19 04:58:38","TRT01EDTM":"2021-02-16 22:06:46","TRT02SDTM":"2021-02-16 22:06:46","TRT02EDTM":"2022-02-17 04:06:46","AP01SDTM":"2020-01-19 04:58:38","AP01EDTM":"2021-02-16 22:06:46","AP02SDTM":"2021-02-16 22:06:46","AP02EDTM":"2022-02-17 04:06:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":760,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-01","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4486,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.77786,"AVALU":"mg/L","BASE2":8.77786,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"4","ADTM":"2020-02-06 04:58:38","ADY":18,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-47","SUBJID":"id-47","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.39866,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 04:58:38","TRTEDTM":"2022-02-17 04:06:46","TRT01SDTM":"2020-01-19 04:58:38","TRT01EDTM":"2021-02-16 22:06:46","TRT02SDTM":"2021-02-16 22:06:46","TRT02EDTM":"2022-02-17 04:06:46","AP01SDTM":"2020-01-19 04:58:38","AP01EDTM":"2021-02-16 22:06:46","AP02SDTM":"2021-02-16 22:06:46","AP02EDTM":"2022-02-17 04:06:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":760,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-01","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1554,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.69842,"AVALU":"mg/L","BASE2":8.77786,"BASE":10.69842,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.92056,"PCHG2":21.87957,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"4","BTOXGR":"4","ADTM":"2020-06-19 04:58:38","ADY":152,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-47","SUBJID":"id-47","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.39866,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 04:58:38","TRTEDTM":"2022-02-17 04:06:46","TRT01SDTM":"2020-01-19 04:58:38","TRT01EDTM":"2021-02-16 22:06:46","TRT02SDTM":"2021-02-16 22:06:46","TRT02EDTM":"2022-02-17 04:06:46","AP01SDTM":"2020-01-19 04:58:38","AP01EDTM":"2021-02-16 22:06:46","AP02SDTM":"2021-02-16 22:06:46","AP02EDTM":"2022-02-17 04:06:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":760,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-01","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3720,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.57296,"AVALU":"mg/L","BASE2":8.77786,"BASE":10.69842,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.7951,"PCHG2":20.4503,"CHG":-0.12546,"PCHG":-1.17269,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"3","BTOXGR":"4","ADTM":"2020-09-11 04:58:38","ADY":236,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-47","SUBJID":"id-47","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.39866,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 04:58:38","TRTEDTM":"2022-02-17 04:06:46","TRT01SDTM":"2020-01-19 04:58:38","TRT01EDTM":"2021-02-16 22:06:46","TRT02SDTM":"2021-02-16 22:06:46","TRT02EDTM":"2022-02-17 04:06:46","AP01SDTM":"2020-01-19 04:58:38","AP01EDTM":"2021-02-16 22:06:46","AP02SDTM":"2021-02-16 22:06:46","AP02EDTM":"2022-02-17 04:06:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":760,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-01","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5511,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.64873,"AVALU":"mg/L","BASE2":8.77786,"BASE":10.69842,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.87087,"PCHG2":9.92123,"CHG":-1.04969,"PCHG":-9.8116,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2021-04-27 04:58:38","ADY":464,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-47","SUBJID":"id-47","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.39866,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 04:58:38","TRTEDTM":"2022-02-17 04:06:46","TRT01SDTM":"2020-01-19 04:58:38","TRT01EDTM":"2021-02-16 22:06:46","TRT02SDTM":"2021-02-16 22:06:46","TRT02EDTM":"2022-02-17 04:06:46","AP01SDTM":"2020-01-19 04:58:38","AP01EDTM":"2021-02-16 22:06:46","AP02SDTM":"2021-02-16 22:06:46","AP02EDTM":"2022-02-17 04:06:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":760,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-01","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6182,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.2834,"AVALU":"mg/L","BASE2":8.77786,"BASE":10.69842,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.49446,"PCHG2":-5.633,"CHG":-2.41501,"PCHG":-22.57357,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2021-07-23 04:58:38","ADY":551,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-47","SUBJID":"id-47","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.39866,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 04:58:38","TRTEDTM":"2022-02-17 04:06:46","TRT01SDTM":"2020-01-19 04:58:38","TRT01EDTM":"2021-02-16 22:06:46","TRT02SDTM":"2021-02-16 22:06:46","TRT02EDTM":"2022-02-17 04:06:46","AP01SDTM":"2020-01-19 04:58:38","AP01EDTM":"2021-02-16 22:06:46","AP02SDTM":"2021-02-16 22:06:46","AP02EDTM":"2022-02-17 04:06:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":760,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-01","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4331,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.49587,"AVALU":"mg/L","BASE2":8.77786,"BASE":10.69842,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.71801,"PCHG2":19.57206,"CHG":-0.20255,"PCHG":-1.89327,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"3","BTOXGR":"4","ADTM":"2021-09-25 04:58:38","ADY":615,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-47","SUBJID":"id-47","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.39866,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 04:58:38","TRTEDTM":"2022-02-17 04:06:46","TRT01SDTM":"2020-01-19 04:58:38","TRT01EDTM":"2021-02-16 22:06:46","TRT02SDTM":"2021-02-16 22:06:46","TRT02EDTM":"2022-02-17 04:06:46","AP01SDTM":"2020-01-19 04:58:38","AP01EDTM":"2021-02-16 22:06:46","AP02SDTM":"2021-02-16 22:06:46","AP02EDTM":"2022-02-17 04:06:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":760,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-01","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2951,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.24493,"AVALU":"mg/L","BASE2":8.77786,"BASE":10.69842,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.46707,"PCHG2":5.32103,"CHG":-1.45348,"PCHG":-13.58598,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2021-10-07 04:58:38","ADY":627,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-47","SUBJID":"id-47","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.39866,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 04:58:38","TRTEDTM":"2022-02-17 04:06:46","TRT01SDTM":"2020-01-19 04:58:38","TRT01EDTM":"2021-02-16 22:06:46","TRT02SDTM":"2021-02-16 22:06:46","TRT02EDTM":"2022-02-17 04:06:46","AP01SDTM":"2020-01-19 04:58:38","AP01EDTM":"2021-02-16 22:06:46","AP02SDTM":"2021-02-16 22:06:46","AP02EDTM":"2022-02-17 04:06:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":760,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-01","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2511,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91523,"AVALU":"g/L","BASE2":2.91523,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"4","ADTM":"2020-02-06 04:58:38","ADY":18,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-47","SUBJID":"id-47","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.39866,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 04:58:38","TRTEDTM":"2022-02-17 04:06:46","TRT01SDTM":"2020-01-19 04:58:38","TRT01EDTM":"2021-02-16 22:06:46","TRT02SDTM":"2021-02-16 22:06:46","TRT02EDTM":"2022-02-17 04:06:46","AP01SDTM":"2020-01-19 04:58:38","AP01EDTM":"2021-02-16 22:06:46","AP02SDTM":"2021-02-16 22:06:46","AP02EDTM":"2022-02-17 04:06:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":760,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-01","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3598,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04376,"AVALU":"g/L","BASE2":2.91523,"BASE":3.04376,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.12853,"PCHG2":4.40905,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"4","BTOXGR":"4","ADTM":"2020-06-19 04:58:38","ADY":152,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-47","SUBJID":"id-47","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.39866,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 04:58:38","TRTEDTM":"2022-02-17 04:06:46","TRT01SDTM":"2020-01-19 04:58:38","TRT01EDTM":"2021-02-16 22:06:46","TRT02SDTM":"2021-02-16 22:06:46","TRT02EDTM":"2022-02-17 04:06:46","AP01SDTM":"2020-01-19 04:58:38","AP01EDTM":"2021-02-16 22:06:46","AP02SDTM":"2021-02-16 22:06:46","AP02EDTM":"2022-02-17 04:06:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":760,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-01","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3870,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86773,"AVALU":"g/L","BASE2":2.91523,"BASE":3.04376,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0475,"PCHG2":-1.62945,"CHG":-0.17604,"PCHG":-5.78351,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2020-09-11 04:58:38","ADY":236,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-47","SUBJID":"id-47","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.39866,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 04:58:38","TRTEDTM":"2022-02-17 04:06:46","TRT01SDTM":"2020-01-19 04:58:38","TRT01EDTM":"2021-02-16 22:06:46","TRT02SDTM":"2021-02-16 22:06:46","TRT02EDTM":"2022-02-17 04:06:46","AP01SDTM":"2020-01-19 04:58:38","AP01EDTM":"2021-02-16 22:06:46","AP02SDTM":"2021-02-16 22:06:46","AP02EDTM":"2022-02-17 04:06:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":760,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-01","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":172,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97192,"AVALU":"g/L","BASE2":2.91523,"BASE":3.04376,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0567,"PCHG2":1.94479,"CHG":-0.07184,"PCHG":-2.3602,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2021-04-27 04:58:38","ADY":464,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-47","SUBJID":"id-47","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.39866,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 04:58:38","TRTEDTM":"2022-02-17 04:06:46","TRT01SDTM":"2020-01-19 04:58:38","TRT01EDTM":"2021-02-16 22:06:46","TRT02SDTM":"2021-02-16 22:06:46","TRT02EDTM":"2022-02-17 04:06:46","AP01SDTM":"2020-01-19 04:58:38","AP01EDTM":"2021-02-16 22:06:46","AP02SDTM":"2021-02-16 22:06:46","AP02EDTM":"2022-02-17 04:06:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":760,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-01","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2879,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93377,"AVALU":"g/L","BASE2":2.91523,"BASE":3.04376,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01854,"PCHG2":0.63599,"CHG":-0.10999,"PCHG":-3.61373,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2021-07-23 04:58:38","ADY":551,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-47","SUBJID":"id-47","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.39866,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 04:58:38","TRTEDTM":"2022-02-17 04:06:46","TRT01SDTM":"2020-01-19 04:58:38","TRT01EDTM":"2021-02-16 22:06:46","TRT02SDTM":"2021-02-16 22:06:46","TRT02EDTM":"2022-02-17 04:06:46","AP01SDTM":"2020-01-19 04:58:38","AP01EDTM":"2021-02-16 22:06:46","AP02SDTM":"2021-02-16 22:06:46","AP02EDTM":"2022-02-17 04:06:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":760,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-01","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2570,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.07833,"AVALU":"g/L","BASE2":2.91523,"BASE":3.04376,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1631,"PCHG2":5.59489,"CHG":0.03457,"PCHG":1.13577,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"4","BTOXGR":"4","ADTM":"2021-09-25 04:58:38","ADY":615,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-47","SUBJID":"id-47","SITEID":"CHN-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.39866,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 04:58:38","TRTEDTM":"2022-02-17 04:06:46","TRT01SDTM":"2020-01-19 04:58:38","TRT01EDTM":"2021-02-16 22:06:46","TRT02SDTM":"2021-02-16 22:06:46","TRT02EDTM":"2022-02-17 04:06:46","AP01SDTM":"2020-01-19 04:58:38","AP01EDTM":"2021-02-16 22:06:46","AP02SDTM":"2021-02-16 22:06:46","AP02EDTM":"2022-02-17 04:06:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":760,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-01","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1474,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96159,"AVALU":"g/L","BASE2":2.91523,"BASE":3.04376,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04636,"PCHG2":1.5903,"CHG":-0.08217,"PCHG":-2.69972,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2021-10-07 04:58:38","ADY":627,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-53","SUBJID":"id-53","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90562,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-04","TRTSDTM":"2019-11-07 07:28:03","TRT01SDTM":"2019-11-07 07:28:03","AP01SDTM":"2019-11-07 07:28:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4374,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.99024,"AVALU":"U/L","BASE2":14.99024,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2019-12-18 07:28:03","ADY":41,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-53","SUBJID":"id-53","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90562,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-04","TRTSDTM":"2019-11-07 07:28:03","TRT01SDTM":"2019-11-07 07:28:03","AP01SDTM":"2019-11-07 07:28:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3144,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.36353,"AVALU":"U/L","BASE2":14.99024,"BASE":6.36353,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-8.6267,"PCHG2":-57.54882,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2020-02-13 07:28:03","ADY":98,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-53","SUBJID":"id-53","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90562,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-04","TRTSDTM":"2019-11-07 07:28:03","TRT01SDTM":"2019-11-07 07:28:03","AP01SDTM":"2019-11-07 07:28:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1735,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.47571,"AVALU":"U/L","BASE2":14.99024,"BASE":6.36353,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.51453,"PCHG2":-36.78749,"CHG":3.11217,"PCHG":48.90635,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-08-06 07:28:03","ADY":273,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-53","SUBJID":"id-53","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90562,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-04","TRTSDTM":"2019-11-07 07:28:03","TRT01SDTM":"2019-11-07 07:28:03","AP01SDTM":"2019-11-07 07:28:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2623,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.64171,"AVALU":"U/L","BASE2":14.99024,"BASE":6.36353,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.34852,"PCHG2":-75.7061,"CHG":-2.72182,"PCHG":-42.77214,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2020-10-15 07:28:03","ADY":343,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-53","SUBJID":"id-53","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90562,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-04","TRTSDTM":"2019-11-07 07:28:03","TRT01SDTM":"2019-11-07 07:28:03","AP01SDTM":"2019-11-07 07:28:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3726,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.13243,"AVALU":"U/L","BASE2":14.99024,"BASE":6.36353,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.85781,"PCHG2":-45.7485,"CHG":1.7689,"PCHG":27.79737,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-12-21 07:28:03","ADY":410,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-53","SUBJID":"id-53","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90562,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-04","TRTSDTM":"2019-11-07 07:28:03","TRT01SDTM":"2019-11-07 07:28:03","AP01SDTM":"2019-11-07 07:28:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8075,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.78572,"AVALU":"U/L","BASE2":14.99024,"BASE":6.36353,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.79548,"PCHG2":18.64866,"CHG":11.42218,"PCHG":179.49435,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-04-20 07:28:03","ADY":530,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-53","SUBJID":"id-53","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90562,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-04","TRTSDTM":"2019-11-07 07:28:03","TRT01SDTM":"2019-11-07 07:28:03","AP01SDTM":"2019-11-07 07:28:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3368,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.8148,"AVALU":"U/L","BASE2":14.99024,"BASE":6.36353,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.17544,"PCHG2":-34.5254,"CHG":3.45127,"PCHG":54.23504,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-09-14 07:28:03","ADY":677,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-53","SUBJID":"id-53","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90562,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-04","TRTSDTM":"2019-11-07 07:28:03","TRT01SDTM":"2019-11-07 07:28:03","AP01SDTM":"2019-11-07 07:28:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7598,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.97502,"AVALU":"mg/L","BASE2":9.97502,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-18 07:28:03","ADY":41,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-53","SUBJID":"id-53","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90562,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-04","TRTSDTM":"2019-11-07 07:28:03","TRT01SDTM":"2019-11-07 07:28:03","AP01SDTM":"2019-11-07 07:28:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6429,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.18439,"AVALU":"mg/L","BASE2":9.97502,"BASE":8.18439,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.79063,"PCHG2":-17.95111,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-13 07:28:03","ADY":98,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-53","SUBJID":"id-53","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90562,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-04","TRTSDTM":"2019-11-07 07:28:03","TRT01SDTM":"2019-11-07 07:28:03","AP01SDTM":"2019-11-07 07:28:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1400,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.1123,"AVALU":"mg/L","BASE2":9.97502,"BASE":8.18439,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.86272,"PCHG2":-18.67384,"CHG":-0.07209,"PCHG":-0.88086,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-06 07:28:03","ADY":273,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-53","SUBJID":"id-53","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90562,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-04","TRTSDTM":"2019-11-07 07:28:03","TRT01SDTM":"2019-11-07 07:28:03","AP01SDTM":"2019-11-07 07:28:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7554,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.83859,"AVALU":"mg/L","BASE2":9.97502,"BASE":8.18439,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.13643,"PCHG2":-21.41782,"CHG":-0.34581,"PCHG":-4.22518,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-10-15 07:28:03","ADY":343,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-53","SUBJID":"id-53","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90562,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-04","TRTSDTM":"2019-11-07 07:28:03","TRT01SDTM":"2019-11-07 07:28:03","AP01SDTM":"2019-11-07 07:28:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1538,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.09128,"AVALU":"mg/L","BASE2":9.97502,"BASE":8.18439,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.88374,"PCHG2":-8.85956,"CHG":0.90688,"PCHG":11.08065,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-21 07:28:03","ADY":410,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-53","SUBJID":"id-53","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90562,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-04","TRTSDTM":"2019-11-07 07:28:03","TRT01SDTM":"2019-11-07 07:28:03","AP01SDTM":"2019-11-07 07:28:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5801,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.15566,"AVALU":"mg/L","BASE2":9.97502,"BASE":8.18439,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.81937,"PCHG2":-18.23921,"CHG":-0.02874,"PCHG":-0.35113,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-20 07:28:03","ADY":530,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-53","SUBJID":"id-53","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90562,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-04","TRTSDTM":"2019-11-07 07:28:03","TRT01SDTM":"2019-11-07 07:28:03","AP01SDTM":"2019-11-07 07:28:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":565,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.55571,"AVALU":"mg/L","BASE2":9.97502,"BASE":8.18439,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.41932,"PCHG2":-14.22869,"CHG":0.37131,"PCHG":4.53683,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-14 07:28:03","ADY":677,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-53","SUBJID":"id-53","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90562,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-04","TRTSDTM":"2019-11-07 07:28:03","TRT01SDTM":"2019-11-07 07:28:03","AP01SDTM":"2019-11-07 07:28:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2955,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82624,"AVALU":"g/L","BASE2":2.82624,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-18 07:28:03","ADY":41,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-53","SUBJID":"id-53","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90562,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-04","TRTSDTM":"2019-11-07 07:28:03","TRT01SDTM":"2019-11-07 07:28:03","AP01SDTM":"2019-11-07 07:28:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":562,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92817,"AVALU":"g/L","BASE2":2.82624,"BASE":2.92817,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.10194,"PCHG2":3.60678,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-13 07:28:03","ADY":98,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-53","SUBJID":"id-53","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90562,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-04","TRTSDTM":"2019-11-07 07:28:03","TRT01SDTM":"2019-11-07 07:28:03","AP01SDTM":"2019-11-07 07:28:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8247,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05288,"AVALU":"g/L","BASE2":2.82624,"BASE":2.92817,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.22664,"PCHG2":8.01909,"CHG":0.1247,"PCHG":4.25871,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-08-06 07:28:03","ADY":273,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-53","SUBJID":"id-53","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90562,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-04","TRTSDTM":"2019-11-07 07:28:03","TRT01SDTM":"2019-11-07 07:28:03","AP01SDTM":"2019-11-07 07:28:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1675,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8999,"AVALU":"g/L","BASE2":2.82624,"BASE":2.92817,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07366,"PCHG2":2.60638,"CHG":-0.02827,"PCHG":-0.96557,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-15 07:28:03","ADY":343,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-53","SUBJID":"id-53","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90562,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-04","TRTSDTM":"2019-11-07 07:28:03","TRT01SDTM":"2019-11-07 07:28:03","AP01SDTM":"2019-11-07 07:28:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":103,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95377,"AVALU":"g/L","BASE2":2.82624,"BASE":2.92817,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12753,"PCHG2":4.5124,"CHG":0.0256,"PCHG":0.8741,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-21 07:28:03","ADY":410,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-53","SUBJID":"id-53","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90562,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-04","TRTSDTM":"2019-11-07 07:28:03","TRT01SDTM":"2019-11-07 07:28:03","AP01SDTM":"2019-11-07 07:28:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3493,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92846,"AVALU":"g/L","BASE2":2.82624,"BASE":2.92817,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10222,"PCHG2":3.6168,"CHG":0.00028,"PCHG":0.00968,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-20 07:28:03","ADY":530,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-53","SUBJID":"id-53","SITEID":"CHN-1","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90562,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-04","TRTSDTM":"2019-11-07 07:28:03","TRT01SDTM":"2019-11-07 07:28:03","AP01SDTM":"2019-11-07 07:28:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":353,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96922,"AVALU":"g/L","BASE2":2.82624,"BASE":2.92817,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14298,"PCHG2":5.05901,"CHG":0.04104,"PCHG":1.40168,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-14 07:28:03","ADY":677,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-62","SUBJID":"id-62","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.50974,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-21","TRTSDTM":"2020-11-22 01:52:11","TRTEDTM":"2022-02-19 14:41:59","TRT01SDTM":"2020-11-22 01:52:11","TRT01EDTM":"2021-02-19 08:41:59","TRT02SDTM":"2021-02-19 08:41:59","TRT02EDTM":"2022-02-19 14:41:59","AP01SDTM":"2020-11-22 01:52:11","AP01EDTM":"2021-02-19 08:41:59","AP02SDTM":"2021-02-19 08:41:59","AP02EDTM":"2022-02-19 14:41:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":455,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":497,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":522,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.96234,"AVALU":"U/L","BASE2":23.96234,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-25 01:52:11","ADY":33,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-62","SUBJID":"id-62","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.50974,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-21","TRTSDTM":"2020-11-22 01:52:11","TRTEDTM":"2022-02-19 14:41:59","TRT01SDTM":"2020-11-22 01:52:11","TRT01EDTM":"2021-02-19 08:41:59","TRT02SDTM":"2021-02-19 08:41:59","TRT02EDTM":"2022-02-19 14:41:59","AP01SDTM":"2020-11-22 01:52:11","AP01EDTM":"2021-02-19 08:41:59","AP02SDTM":"2021-02-19 08:41:59","AP02EDTM":"2022-02-19 14:41:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":455,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":497,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1273,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.86059,"AVALU":"U/L","BASE2":23.96234,"BASE":22.86059,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.10175,"PCHG2":-4.59785,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-21 01:52:11","ADY":60,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-62","SUBJID":"id-62","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.50974,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-21","TRTSDTM":"2020-11-22 01:52:11","TRTEDTM":"2022-02-19 14:41:59","TRT01SDTM":"2020-11-22 01:52:11","TRT01EDTM":"2021-02-19 08:41:59","TRT02SDTM":"2021-02-19 08:41:59","TRT02EDTM":"2022-02-19 14:41:59","AP01SDTM":"2020-11-22 01:52:11","AP01EDTM":"2021-02-19 08:41:59","AP02SDTM":"2021-02-19 08:41:59","AP02EDTM":"2022-02-19 14:41:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":455,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":497,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":524,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.15447,"AVALU":"U/L","BASE2":23.96234,"BASE":22.86059,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-18.80787,"PCHG2":-78.48929,"CHG":-17.70612,"PCHG":-77.45259,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-07-08 01:52:11","ADY":228,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-62","SUBJID":"id-62","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.50974,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-21","TRTSDTM":"2020-11-22 01:52:11","TRTEDTM":"2022-02-19 14:41:59","TRT01SDTM":"2020-11-22 01:52:11","TRT01EDTM":"2021-02-19 08:41:59","TRT02SDTM":"2021-02-19 08:41:59","TRT02EDTM":"2022-02-19 14:41:59","AP01SDTM":"2020-11-22 01:52:11","AP01EDTM":"2021-02-19 08:41:59","AP02SDTM":"2021-02-19 08:41:59","AP02EDTM":"2022-02-19 14:41:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":455,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":497,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3993,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.1099,"AVALU":"U/L","BASE2":23.96234,"BASE":22.86059,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.85245,"PCHG2":-32.76994,"CHG":-6.75069,"PCHG":-29.52983,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-12 01:52:11","ADY":263,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-62","SUBJID":"id-62","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.50974,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-21","TRTSDTM":"2020-11-22 01:52:11","TRTEDTM":"2022-02-19 14:41:59","TRT01SDTM":"2020-11-22 01:52:11","TRT01EDTM":"2021-02-19 08:41:59","TRT02SDTM":"2021-02-19 08:41:59","TRT02EDTM":"2022-02-19 14:41:59","AP01SDTM":"2020-11-22 01:52:11","AP01EDTM":"2021-02-19 08:41:59","AP02SDTM":"2021-02-19 08:41:59","AP02EDTM":"2022-02-19 14:41:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":455,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":497,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6224,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.75929,"AVALU":"U/L","BASE2":23.96234,"BASE":22.86059,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.20305,"PCHG2":-5.0206,"CHG":-0.1013,"PCHG":-0.44312,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-02 01:52:11","ADY":375,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-62","SUBJID":"id-62","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.50974,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-21","TRTSDTM":"2020-11-22 01:52:11","TRTEDTM":"2022-02-19 14:41:59","TRT01SDTM":"2020-11-22 01:52:11","TRT01EDTM":"2021-02-19 08:41:59","TRT02SDTM":"2021-02-19 08:41:59","TRT02EDTM":"2022-02-19 14:41:59","AP01SDTM":"2020-11-22 01:52:11","AP01EDTM":"2021-02-19 08:41:59","AP02SDTM":"2021-02-19 08:41:59","AP02EDTM":"2022-02-19 14:41:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":455,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":497,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1075,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.64444,"AVALU":"U/L","BASE2":23.96234,"BASE":22.86059,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.3179,"PCHG2":-47.23204,"CHG":-10.21615,"PCHG":-44.68893,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-10 01:52:11","ADY":383,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-62","SUBJID":"id-62","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.50974,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-21","TRTSDTM":"2020-11-22 01:52:11","TRTEDTM":"2022-02-19 14:41:59","TRT01SDTM":"2020-11-22 01:52:11","TRT01EDTM":"2021-02-19 08:41:59","TRT02SDTM":"2021-02-19 08:41:59","TRT02EDTM":"2022-02-19 14:41:59","AP01SDTM":"2020-11-22 01:52:11","AP01EDTM":"2021-02-19 08:41:59","AP02SDTM":"2021-02-19 08:41:59","AP02EDTM":"2022-02-19 14:41:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":455,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":497,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6152,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.82403,"AVALU":"U/L","BASE2":23.96234,"BASE":22.86059,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.13831,"PCHG2":-54.829,"CHG":-12.03656,"PCHG":-52.65202,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-07 01:52:11","ADY":411,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-62","SUBJID":"id-62","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.50974,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-21","TRTSDTM":"2020-11-22 01:52:11","TRTEDTM":"2022-02-19 14:41:59","TRT01SDTM":"2020-11-22 01:52:11","TRT01EDTM":"2021-02-19 08:41:59","TRT02SDTM":"2021-02-19 08:41:59","TRT02EDTM":"2022-02-19 14:41:59","AP01SDTM":"2020-11-22 01:52:11","AP01EDTM":"2021-02-19 08:41:59","AP02SDTM":"2021-02-19 08:41:59","AP02EDTM":"2022-02-19 14:41:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":455,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":497,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1542,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.26802,"AVALU":"mg/L","BASE2":7.26802,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-4","ADTM":"2020-12-25 01:52:11","ADY":33,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-62","SUBJID":"id-62","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.50974,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-21","TRTSDTM":"2020-11-22 01:52:11","TRTEDTM":"2022-02-19 14:41:59","TRT01SDTM":"2020-11-22 01:52:11","TRT01EDTM":"2021-02-19 08:41:59","TRT02SDTM":"2021-02-19 08:41:59","TRT02EDTM":"2022-02-19 14:41:59","AP01SDTM":"2020-11-22 01:52:11","AP01EDTM":"2021-02-19 08:41:59","AP02SDTM":"2021-02-19 08:41:59","AP02EDTM":"2022-02-19 14:41:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":455,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":497,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1422,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.97432,"AVALU":"mg/L","BASE2":7.26802,"BASE":7.97432,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.7063,"PCHG2":9.71789,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-4","BTOXGR":"-4","ADTM":"2021-01-21 01:52:11","ADY":60,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-62","SUBJID":"id-62","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.50974,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-21","TRTSDTM":"2020-11-22 01:52:11","TRTEDTM":"2022-02-19 14:41:59","TRT01SDTM":"2020-11-22 01:52:11","TRT01EDTM":"2021-02-19 08:41:59","TRT02SDTM":"2021-02-19 08:41:59","TRT02EDTM":"2022-02-19 14:41:59","AP01SDTM":"2020-11-22 01:52:11","AP01EDTM":"2021-02-19 08:41:59","AP02SDTM":"2021-02-19 08:41:59","AP02EDTM":"2022-02-19 14:41:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":455,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":497,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":397,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.56243,"AVALU":"mg/L","BASE2":7.26802,"BASE":7.97432,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.29441,"PCHG2":45.3275,"CHG":2.58811,"PCHG":32.45561,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"1","BTOXGR":"-4","ADTM":"2021-07-08 01:52:11","ADY":228,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-62","SUBJID":"id-62","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.50974,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-21","TRTSDTM":"2020-11-22 01:52:11","TRTEDTM":"2022-02-19 14:41:59","TRT01SDTM":"2020-11-22 01:52:11","TRT01EDTM":"2021-02-19 08:41:59","TRT02SDTM":"2021-02-19 08:41:59","TRT02EDTM":"2022-02-19 14:41:59","AP01SDTM":"2020-11-22 01:52:11","AP01EDTM":"2021-02-19 08:41:59","AP02SDTM":"2021-02-19 08:41:59","AP02EDTM":"2022-02-19 14:41:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":455,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":497,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5108,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.23509,"AVALU":"mg/L","BASE2":7.26802,"BASE":7.97432,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.96707,"PCHG2":13.30584,"CHG":0.26077,"PCHG":3.27015,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-08-12 01:52:11","ADY":263,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-62","SUBJID":"id-62","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.50974,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-21","TRTSDTM":"2020-11-22 01:52:11","TRTEDTM":"2022-02-19 14:41:59","TRT01SDTM":"2020-11-22 01:52:11","TRT01EDTM":"2021-02-19 08:41:59","TRT02SDTM":"2021-02-19 08:41:59","TRT02EDTM":"2022-02-19 14:41:59","AP01SDTM":"2020-11-22 01:52:11","AP01EDTM":"2021-02-19 08:41:59","AP02SDTM":"2021-02-19 08:41:59","AP02EDTM":"2022-02-19 14:41:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":455,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":497,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5372,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.09826,"AVALU":"mg/L","BASE2":7.26802,"BASE":7.97432,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.83024,"PCHG2":38.94108,"CHG":2.12395,"PCHG":26.63484,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"1","BTOXGR":"-4","ADTM":"2021-12-02 01:52:11","ADY":375,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-62","SUBJID":"id-62","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.50974,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-21","TRTSDTM":"2020-11-22 01:52:11","TRTEDTM":"2022-02-19 14:41:59","TRT01SDTM":"2020-11-22 01:52:11","TRT01EDTM":"2021-02-19 08:41:59","TRT02SDTM":"2021-02-19 08:41:59","TRT02EDTM":"2022-02-19 14:41:59","AP01SDTM":"2020-11-22 01:52:11","AP01EDTM":"2021-02-19 08:41:59","AP02SDTM":"2021-02-19 08:41:59","AP02EDTM":"2022-02-19 14:41:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":455,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":497,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2048,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.17894,"AVALU":"mg/L","BASE2":7.26802,"BASE":7.97432,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.91093,"PCHG2":26.29228,"CHG":1.20463,"PCHG":15.10637,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-12-10 01:52:11","ADY":383,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-62","SUBJID":"id-62","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.50974,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-21","TRTSDTM":"2020-11-22 01:52:11","TRTEDTM":"2022-02-19 14:41:59","TRT01SDTM":"2020-11-22 01:52:11","TRT01EDTM":"2021-02-19 08:41:59","TRT02SDTM":"2021-02-19 08:41:59","TRT02EDTM":"2022-02-19 14:41:59","AP01SDTM":"2020-11-22 01:52:11","AP01EDTM":"2021-02-19 08:41:59","AP02SDTM":"2021-02-19 08:41:59","AP02EDTM":"2022-02-19 14:41:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":455,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":497,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1537,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.23019,"AVALU":"mg/L","BASE2":7.26802,"BASE":7.97432,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.96217,"PCHG2":26.99737,"CHG":1.25588,"PCHG":15.749,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2022-01-07 01:52:11","ADY":411,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-62","SUBJID":"id-62","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.50974,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-21","TRTSDTM":"2020-11-22 01:52:11","TRTEDTM":"2022-02-19 14:41:59","TRT01SDTM":"2020-11-22 01:52:11","TRT01EDTM":"2021-02-19 08:41:59","TRT02SDTM":"2021-02-19 08:41:59","TRT02EDTM":"2022-02-19 14:41:59","AP01SDTM":"2020-11-22 01:52:11","AP01EDTM":"2021-02-19 08:41:59","AP02SDTM":"2021-02-19 08:41:59","AP02EDTM":"2022-02-19 14:41:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":455,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":497,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":461,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04424,"AVALU":"g/L","BASE2":3.04424,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-12-25 01:52:11","ADY":33,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-62","SUBJID":"id-62","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.50974,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-21","TRTSDTM":"2020-11-22 01:52:11","TRTEDTM":"2022-02-19 14:41:59","TRT01SDTM":"2020-11-22 01:52:11","TRT01EDTM":"2021-02-19 08:41:59","TRT02SDTM":"2021-02-19 08:41:59","TRT02EDTM":"2022-02-19 14:41:59","AP01SDTM":"2020-11-22 01:52:11","AP01EDTM":"2021-02-19 08:41:59","AP02SDTM":"2021-02-19 08:41:59","AP02EDTM":"2022-02-19 14:41:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":455,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":497,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5190,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85171,"AVALU":"g/L","BASE2":3.04424,"BASE":2.85171,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.19253,"PCHG2":-6.32435,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-21 01:52:11","ADY":60,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-62","SUBJID":"id-62","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.50974,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-21","TRTSDTM":"2020-11-22 01:52:11","TRTEDTM":"2022-02-19 14:41:59","TRT01SDTM":"2020-11-22 01:52:11","TRT01EDTM":"2021-02-19 08:41:59","TRT02SDTM":"2021-02-19 08:41:59","TRT02EDTM":"2022-02-19 14:41:59","AP01SDTM":"2020-11-22 01:52:11","AP01EDTM":"2021-02-19 08:41:59","AP02SDTM":"2021-02-19 08:41:59","AP02EDTM":"2022-02-19 14:41:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":455,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":497,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2534,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97688,"AVALU":"g/L","BASE2":3.04424,"BASE":2.85171,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06736,"PCHG2":-2.2127,"CHG":0.12517,"PCHG":4.38925,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-08 01:52:11","ADY":228,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-62","SUBJID":"id-62","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.50974,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-21","TRTSDTM":"2020-11-22 01:52:11","TRTEDTM":"2022-02-19 14:41:59","TRT01SDTM":"2020-11-22 01:52:11","TRT01EDTM":"2021-02-19 08:41:59","TRT02SDTM":"2021-02-19 08:41:59","TRT02EDTM":"2022-02-19 14:41:59","AP01SDTM":"2020-11-22 01:52:11","AP01EDTM":"2021-02-19 08:41:59","AP02SDTM":"2021-02-19 08:41:59","AP02EDTM":"2022-02-19 14:41:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":455,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":497,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2193,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88687,"AVALU":"g/L","BASE2":3.04424,"BASE":2.85171,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15737,"PCHG2":-5.16934,"CHG":0.03516,"PCHG":1.23299,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-12 01:52:11","ADY":263,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-62","SUBJID":"id-62","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.50974,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-21","TRTSDTM":"2020-11-22 01:52:11","TRTEDTM":"2022-02-19 14:41:59","TRT01SDTM":"2020-11-22 01:52:11","TRT01EDTM":"2021-02-19 08:41:59","TRT02SDTM":"2021-02-19 08:41:59","TRT02EDTM":"2022-02-19 14:41:59","AP01SDTM":"2020-11-22 01:52:11","AP01EDTM":"2021-02-19 08:41:59","AP02SDTM":"2021-02-19 08:41:59","AP02EDTM":"2022-02-19 14:41:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":455,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":497,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":472,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95285,"AVALU":"g/L","BASE2":3.04424,"BASE":2.85171,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09139,"PCHG2":-3.002,"CHG":0.10114,"PCHG":3.54666,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-02 01:52:11","ADY":375,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-62","SUBJID":"id-62","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.50974,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-21","TRTSDTM":"2020-11-22 01:52:11","TRTEDTM":"2022-02-19 14:41:59","TRT01SDTM":"2020-11-22 01:52:11","TRT01EDTM":"2021-02-19 08:41:59","TRT02SDTM":"2021-02-19 08:41:59","TRT02EDTM":"2022-02-19 14:41:59","AP01SDTM":"2020-11-22 01:52:11","AP01EDTM":"2021-02-19 08:41:59","AP02SDTM":"2021-02-19 08:41:59","AP02EDTM":"2022-02-19 14:41:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":455,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":497,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3680,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86164,"AVALU":"g/L","BASE2":3.04424,"BASE":2.85171,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18259,"PCHG2":-5.99796,"CHG":0.00994,"PCHG":0.34843,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-10 01:52:11","ADY":383,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-62","SUBJID":"id-62","SITEID":"CHN-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.50974,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-21","TRTSDTM":"2020-11-22 01:52:11","TRTEDTM":"2022-02-19 14:41:59","TRT01SDTM":"2020-11-22 01:52:11","TRT01EDTM":"2021-02-19 08:41:59","TRT02SDTM":"2021-02-19 08:41:59","TRT02EDTM":"2022-02-19 14:41:59","AP01SDTM":"2020-11-22 01:52:11","AP01EDTM":"2021-02-19 08:41:59","AP02SDTM":"2021-02-19 08:41:59","AP02EDTM":"2022-02-19 14:41:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":455,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":497,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6649,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01019,"AVALU":"g/L","BASE2":3.04424,"BASE":2.85171,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03405,"PCHG2":-1.11841,"CHG":0.15848,"PCHG":5.55742,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2022-01-07 01:52:11","ADY":411,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-64","SUBJID":"id-64","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.16063,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-28 02:41:32","TRTEDTM":"2022-02-14 10:26:53","TRT01SDTM":"2019-04-28 02:41:32","TRT01EDTM":"2021-02-14 04:26:53","TRT02SDTM":"2021-02-14 04:26:53","TRT02EDTM":"2022-02-14 10:26:53","AP01SDTM":"2019-04-28 02:41:32","AP01EDTM":"2021-02-14 04:26:53","AP02SDTM":"2021-02-14 04:26:53","AP02EDTM":"2022-02-14 10:26:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1024,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-03","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1804,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.97212,"AVALU":"U/L","BASE2":16.97212,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-05-24 02:41:32","ADY":26,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-64","SUBJID":"id-64","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.16063,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-28 02:41:32","TRTEDTM":"2022-02-14 10:26:53","TRT01SDTM":"2019-04-28 02:41:32","TRT01EDTM":"2021-02-14 04:26:53","TRT02SDTM":"2021-02-14 04:26:53","TRT02EDTM":"2022-02-14 10:26:53","AP01SDTM":"2019-04-28 02:41:32","AP01EDTM":"2021-02-14 04:26:53","AP02SDTM":"2021-02-14 04:26:53","AP02EDTM":"2022-02-14 10:26:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1024,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-03","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4052,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.3433,"AVALU":"U/L","BASE2":16.97212,"BASE":25.3433,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":8.37118,"PCHG2":49.32312,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-23 02:41:32","ADY":239,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-64","SUBJID":"id-64","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.16063,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-28 02:41:32","TRTEDTM":"2022-02-14 10:26:53","TRT01SDTM":"2019-04-28 02:41:32","TRT01EDTM":"2021-02-14 04:26:53","TRT02SDTM":"2021-02-14 04:26:53","TRT02EDTM":"2022-02-14 10:26:53","AP01SDTM":"2019-04-28 02:41:32","AP01EDTM":"2021-02-14 04:26:53","AP02SDTM":"2021-02-14 04:26:53","AP02EDTM":"2022-02-14 10:26:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1024,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-03","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1215,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.73183,"AVALU":"U/L","BASE2":16.97212,"BASE":25.3433,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.2403,"PCHG2":-66.22799,"CHG":-19.61148,"PCHG":-77.38327,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-02-03 02:41:32","ADY":281,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-64","SUBJID":"id-64","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.16063,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-28 02:41:32","TRTEDTM":"2022-02-14 10:26:53","TRT01SDTM":"2019-04-28 02:41:32","TRT01EDTM":"2021-02-14 04:26:53","TRT02SDTM":"2021-02-14 04:26:53","TRT02EDTM":"2022-02-14 10:26:53","AP01SDTM":"2019-04-28 02:41:32","AP01EDTM":"2021-02-14 04:26:53","AP02SDTM":"2021-02-14 04:26:53","AP02EDTM":"2022-02-14 10:26:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1024,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-03","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7106,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.40689,"AVALU":"U/L","BASE2":16.97212,"BASE":25.3433,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.56524,"PCHG2":-97.60262,"CHG":-24.93642,"PCHG":-98.3945,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-01-09 02:41:32","ADY":622,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-64","SUBJID":"id-64","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.16063,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-28 02:41:32","TRTEDTM":"2022-02-14 10:26:53","TRT01SDTM":"2019-04-28 02:41:32","TRT01EDTM":"2021-02-14 04:26:53","TRT02SDTM":"2021-02-14 04:26:53","TRT02EDTM":"2022-02-14 10:26:53","AP01SDTM":"2019-04-28 02:41:32","AP01EDTM":"2021-02-14 04:26:53","AP02SDTM":"2021-02-14 04:26:53","AP02EDTM":"2022-02-14 10:26:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1024,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-03","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6475,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.63645,"AVALU":"U/L","BASE2":16.97212,"BASE":25.3433,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.66433,"PCHG2":56.94237,"CHG":1.29315,"PCHG":5.10253,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-25 02:41:32","ADY":697,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-64","SUBJID":"id-64","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.16063,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-28 02:41:32","TRTEDTM":"2022-02-14 10:26:53","TRT01SDTM":"2019-04-28 02:41:32","TRT01EDTM":"2021-02-14 04:26:53","TRT02SDTM":"2021-02-14 04:26:53","TRT02EDTM":"2022-02-14 10:26:53","AP01SDTM":"2019-04-28 02:41:32","AP01EDTM":"2021-02-14 04:26:53","AP02SDTM":"2021-02-14 04:26:53","AP02EDTM":"2022-02-14 10:26:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1024,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-03","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":622,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.72182,"AVALU":"U/L","BASE2":16.97212,"BASE":25.3433,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.25031,"PCHG2":-95.74705,"CHG":-24.62149,"PCHG":-97.15185,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-09-15 02:41:32","ADY":871,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-64","SUBJID":"id-64","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.16063,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-28 02:41:32","TRTEDTM":"2022-02-14 10:26:53","TRT01SDTM":"2019-04-28 02:41:32","TRT01EDTM":"2021-02-14 04:26:53","TRT02SDTM":"2021-02-14 04:26:53","TRT02EDTM":"2022-02-14 10:26:53","AP01SDTM":"2019-04-28 02:41:32","AP01EDTM":"2021-02-14 04:26:53","AP02SDTM":"2021-02-14 04:26:53","AP02EDTM":"2022-02-14 10:26:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1024,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-03","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8330,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.02481,"AVALU":"U/L","BASE2":16.97212,"BASE":25.3433,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.05269,"PCHG2":17.9865,"CHG":-5.31849,"PCHG":-20.98578,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-05 02:41:32","ADY":1014,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-64","SUBJID":"id-64","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.16063,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-28 02:41:32","TRTEDTM":"2022-02-14 10:26:53","TRT01SDTM":"2019-04-28 02:41:32","TRT01EDTM":"2021-02-14 04:26:53","TRT02SDTM":"2021-02-14 04:26:53","TRT02EDTM":"2022-02-14 10:26:53","AP01SDTM":"2019-04-28 02:41:32","AP01EDTM":"2021-02-14 04:26:53","AP02SDTM":"2021-02-14 04:26:53","AP02EDTM":"2022-02-14 10:26:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1024,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-03","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4961,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.44862,"AVALU":"mg/L","BASE2":10.44862,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"3","BTOXGR":"0","ADTM":"2019-05-24 02:41:32","ADY":26,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-64","SUBJID":"id-64","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.16063,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-28 02:41:32","TRTEDTM":"2022-02-14 10:26:53","TRT01SDTM":"2019-04-28 02:41:32","TRT01EDTM":"2021-02-14 04:26:53","TRT02SDTM":"2021-02-14 04:26:53","TRT02EDTM":"2022-02-14 10:26:53","AP01SDTM":"2019-04-28 02:41:32","AP01EDTM":"2021-02-14 04:26:53","AP02SDTM":"2021-02-14 04:26:53","AP02EDTM":"2022-02-14 10:26:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1024,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-03","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4320,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.20834,"AVALU":"mg/L","BASE2":10.44862,"BASE":9.20834,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.24028,"PCHG2":-11.87025,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-23 02:41:32","ADY":239,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-64","SUBJID":"id-64","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.16063,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-28 02:41:32","TRTEDTM":"2022-02-14 10:26:53","TRT01SDTM":"2019-04-28 02:41:32","TRT01EDTM":"2021-02-14 04:26:53","TRT02SDTM":"2021-02-14 04:26:53","TRT02EDTM":"2022-02-14 10:26:53","AP01SDTM":"2019-04-28 02:41:32","AP01EDTM":"2021-02-14 04:26:53","AP02SDTM":"2021-02-14 04:26:53","AP02EDTM":"2022-02-14 10:26:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1024,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-03","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4508,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.03858,"AVALU":"mg/L","BASE2":10.44862,"BASE":9.20834,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.58996,"PCHG2":5.64625,"CHG":1.83023,"PCHG":19.87582,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-02-03 02:41:32","ADY":281,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-64","SUBJID":"id-64","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.16063,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-28 02:41:32","TRTEDTM":"2022-02-14 10:26:53","TRT01SDTM":"2019-04-28 02:41:32","TRT01EDTM":"2021-02-14 04:26:53","TRT02SDTM":"2021-02-14 04:26:53","TRT02EDTM":"2022-02-14 10:26:53","AP01SDTM":"2019-04-28 02:41:32","AP01EDTM":"2021-02-14 04:26:53","AP02SDTM":"2021-02-14 04:26:53","AP02EDTM":"2022-02-14 10:26:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1024,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-03","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2401,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.98441,"AVALU":"mg/L","BASE2":10.44862,"BASE":9.20834,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.46421,"PCHG2":-14.01343,"CHG":-0.22393,"PCHG":-2.43184,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-09 02:41:32","ADY":622,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-64","SUBJID":"id-64","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.16063,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-28 02:41:32","TRTEDTM":"2022-02-14 10:26:53","TRT01SDTM":"2019-04-28 02:41:32","TRT01EDTM":"2021-02-14 04:26:53","TRT02SDTM":"2021-02-14 04:26:53","TRT02EDTM":"2022-02-14 10:26:53","AP01SDTM":"2019-04-28 02:41:32","AP01EDTM":"2021-02-14 04:26:53","AP02SDTM":"2021-02-14 04:26:53","AP02EDTM":"2022-02-14 10:26:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1024,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-03","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1802,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.77212,"AVALU":"mg/L","BASE2":10.44862,"BASE":9.20834,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.6765,"PCHG2":-6.47454,"CHG":0.56378,"PCHG":6.12247,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-25 02:41:32","ADY":697,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-64","SUBJID":"id-64","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.16063,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-28 02:41:32","TRTEDTM":"2022-02-14 10:26:53","TRT01SDTM":"2019-04-28 02:41:32","TRT01EDTM":"2021-02-14 04:26:53","TRT02SDTM":"2021-02-14 04:26:53","TRT02EDTM":"2022-02-14 10:26:53","AP01SDTM":"2019-04-28 02:41:32","AP01EDTM":"2021-02-14 04:26:53","AP02SDTM":"2021-02-14 04:26:53","AP02EDTM":"2022-02-14 10:26:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1024,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-03","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2792,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.52253,"AVALU":"mg/L","BASE2":10.44862,"BASE":9.20834,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.92609,"PCHG2":-8.86328,"CHG":0.31419,"PCHG":3.41198,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-15 02:41:32","ADY":871,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-64","SUBJID":"id-64","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.16063,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-28 02:41:32","TRTEDTM":"2022-02-14 10:26:53","TRT01SDTM":"2019-04-28 02:41:32","TRT01EDTM":"2021-02-14 04:26:53","TRT02SDTM":"2021-02-14 04:26:53","TRT02EDTM":"2022-02-14 10:26:53","AP01SDTM":"2019-04-28 02:41:32","AP01EDTM":"2021-02-14 04:26:53","AP02SDTM":"2021-02-14 04:26:53","AP02EDTM":"2022-02-14 10:26:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1024,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-03","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4887,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.16481,"AVALU":"mg/L","BASE2":10.44862,"BASE":9.20834,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.28381,"PCHG2":-12.2869,"CHG":-0.04353,"PCHG":-0.47277,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-05 02:41:32","ADY":1014,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-64","SUBJID":"id-64","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.16063,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-28 02:41:32","TRTEDTM":"2022-02-14 10:26:53","TRT01SDTM":"2019-04-28 02:41:32","TRT01EDTM":"2021-02-14 04:26:53","TRT02SDTM":"2021-02-14 04:26:53","TRT02EDTM":"2022-02-14 10:26:53","AP01SDTM":"2019-04-28 02:41:32","AP01EDTM":"2021-02-14 04:26:53","AP02SDTM":"2021-02-14 04:26:53","AP02EDTM":"2022-02-14 10:26:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1024,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-03","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4234,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94684,"AVALU":"g/L","BASE2":2.94684,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-05-24 02:41:32","ADY":26,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-64","SUBJID":"id-64","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.16063,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-28 02:41:32","TRTEDTM":"2022-02-14 10:26:53","TRT01SDTM":"2019-04-28 02:41:32","TRT01EDTM":"2021-02-14 04:26:53","TRT02SDTM":"2021-02-14 04:26:53","TRT02EDTM":"2022-02-14 10:26:53","AP01SDTM":"2019-04-28 02:41:32","AP01EDTM":"2021-02-14 04:26:53","AP02SDTM":"2021-02-14 04:26:53","AP02EDTM":"2022-02-14 10:26:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1024,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-03","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4594,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89517,"AVALU":"g/L","BASE2":2.94684,"BASE":2.89517,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.05167,"PCHG2":-1.75328,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-23 02:41:32","ADY":239,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-64","SUBJID":"id-64","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.16063,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-28 02:41:32","TRTEDTM":"2022-02-14 10:26:53","TRT01SDTM":"2019-04-28 02:41:32","TRT01EDTM":"2021-02-14 04:26:53","TRT02SDTM":"2021-02-14 04:26:53","TRT02EDTM":"2022-02-14 10:26:53","AP01SDTM":"2019-04-28 02:41:32","AP01EDTM":"2021-02-14 04:26:53","AP02SDTM":"2021-02-14 04:26:53","AP02EDTM":"2022-02-14 10:26:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1024,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-03","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4323,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.776,"AVALU":"g/L","BASE2":2.94684,"BASE":2.89517,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17084,"PCHG2":-5.79749,"CHG":-0.11918,"PCHG":-4.11638,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-03 02:41:32","ADY":281,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-64","SUBJID":"id-64","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.16063,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-28 02:41:32","TRTEDTM":"2022-02-14 10:26:53","TRT01SDTM":"2019-04-28 02:41:32","TRT01EDTM":"2021-02-14 04:26:53","TRT02SDTM":"2021-02-14 04:26:53","TRT02EDTM":"2022-02-14 10:26:53","AP01SDTM":"2019-04-28 02:41:32","AP01EDTM":"2021-02-14 04:26:53","AP02SDTM":"2021-02-14 04:26:53","AP02EDTM":"2022-02-14 10:26:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1024,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-03","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3806,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00789,"AVALU":"g/L","BASE2":2.94684,"BASE":2.89517,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06105,"PCHG2":2.07163,"CHG":0.11271,"PCHG":3.89317,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-01-09 02:41:32","ADY":622,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-64","SUBJID":"id-64","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.16063,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-28 02:41:32","TRTEDTM":"2022-02-14 10:26:53","TRT01SDTM":"2019-04-28 02:41:32","TRT01EDTM":"2021-02-14 04:26:53","TRT02SDTM":"2021-02-14 04:26:53","TRT02EDTM":"2022-02-14 10:26:53","AP01SDTM":"2019-04-28 02:41:32","AP01EDTM":"2021-02-14 04:26:53","AP02SDTM":"2021-02-14 04:26:53","AP02EDTM":"2022-02-14 10:26:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1024,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-03","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2855,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92872,"AVALU":"g/L","BASE2":2.94684,"BASE":2.89517,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01812,"PCHG2":-0.61473,"CHG":0.03355,"PCHG":1.15886,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-25 02:41:32","ADY":697,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-64","SUBJID":"id-64","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.16063,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-28 02:41:32","TRTEDTM":"2022-02-14 10:26:53","TRT01SDTM":"2019-04-28 02:41:32","TRT01EDTM":"2021-02-14 04:26:53","TRT02SDTM":"2021-02-14 04:26:53","TRT02EDTM":"2022-02-14 10:26:53","AP01SDTM":"2019-04-28 02:41:32","AP01EDTM":"2021-02-14 04:26:53","AP02SDTM":"2021-02-14 04:26:53","AP02EDTM":"2022-02-14 10:26:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1024,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-03","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6685,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83978,"AVALU":"g/L","BASE2":2.94684,"BASE":2.89517,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10705,"PCHG2":-3.63284,"CHG":-0.05539,"PCHG":-1.9131,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-15 02:41:32","ADY":871,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-64","SUBJID":"id-64","SITEID":"CHN-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.16063,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-28 02:41:32","TRTEDTM":"2022-02-14 10:26:53","TRT01SDTM":"2019-04-28 02:41:32","TRT01EDTM":"2021-02-14 04:26:53","TRT02SDTM":"2021-02-14 04:26:53","TRT02EDTM":"2022-02-14 10:26:53","AP01SDTM":"2019-04-28 02:41:32","AP01EDTM":"2021-02-14 04:26:53","AP02SDTM":"2021-02-14 04:26:53","AP02EDTM":"2022-02-14 10:26:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1024,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-03","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1001,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93475,"AVALU":"g/L","BASE2":2.94684,"BASE":2.89517,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01209,"PCHG2":-0.41034,"CHG":0.03957,"PCHG":1.3669,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-05 02:41:32","ADY":1014,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-69","SUBJID":"id-69","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.54,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-01","TRTSDTM":"2020-04-04 18:42:05","TRTEDTM":"2022-02-19 15:27:41","TRT01SDTM":"2020-04-04 18:42:05","TRT01EDTM":"2021-02-19 09:27:41","TRT02SDTM":"2021-02-19 09:27:41","TRT02EDTM":"2022-02-19 15:27:41","AP01SDTM":"2020-04-04 18:42:05","AP01EDTM":"2021-02-19 09:27:41","AP02SDTM":"2021-02-19 09:27:41","AP02EDTM":"2022-02-19 15:27:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":686,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-19","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5428,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.01821,"AVALU":"U/L","BASE2":17.01821,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-26 18:42:05","ADY":144,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-69","SUBJID":"id-69","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.54,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-01","TRTSDTM":"2020-04-04 18:42:05","TRTEDTM":"2022-02-19 15:27:41","TRT01SDTM":"2020-04-04 18:42:05","TRT01EDTM":"2021-02-19 09:27:41","TRT02SDTM":"2021-02-19 09:27:41","TRT02EDTM":"2022-02-19 15:27:41","AP01SDTM":"2020-04-04 18:42:05","AP01EDTM":"2021-02-19 09:27:41","AP02SDTM":"2021-02-19 09:27:41","AP02EDTM":"2022-02-19 15:27:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":686,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-19","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3690,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.37357,"AVALU":"U/L","BASE2":17.01821,"BASE":18.37357,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.35535,"PCHG2":7.96413,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-08 18:42:05","ADY":157,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-69","SUBJID":"id-69","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.54,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-01","TRTSDTM":"2020-04-04 18:42:05","TRTEDTM":"2022-02-19 15:27:41","TRT01SDTM":"2020-04-04 18:42:05","TRT01EDTM":"2021-02-19 09:27:41","TRT02SDTM":"2021-02-19 09:27:41","TRT02EDTM":"2022-02-19 15:27:41","AP01SDTM":"2020-04-04 18:42:05","AP01EDTM":"2021-02-19 09:27:41","AP02SDTM":"2021-02-19 09:27:41","AP02EDTM":"2022-02-19 15:27:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":686,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-19","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3389,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.98475,"AVALU":"U/L","BASE2":17.01821,"BASE":18.37357,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.03346,"PCHG2":-47.2051,"CHG":-9.38882,"PCHG":-51.09959,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-01 18:42:05","ADY":180,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-69","SUBJID":"id-69","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.54,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-01","TRTSDTM":"2020-04-04 18:42:05","TRTEDTM":"2022-02-19 15:27:41","TRT01SDTM":"2020-04-04 18:42:05","TRT01EDTM":"2021-02-19 09:27:41","TRT02SDTM":"2021-02-19 09:27:41","TRT02EDTM":"2022-02-19 15:27:41","AP01SDTM":"2020-04-04 18:42:05","AP01EDTM":"2021-02-19 09:27:41","AP02SDTM":"2021-02-19 09:27:41","AP02EDTM":"2022-02-19 15:27:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":686,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-19","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2171,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.08643,"AVALU":"U/L","BASE2":17.01821,"BASE":18.37357,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.06822,"PCHG2":65.03751,"CHG":9.71287,"PCHG":52.86327,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-06 18:42:05","ADY":246,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-69","SUBJID":"id-69","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.54,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-01","TRTSDTM":"2020-04-04 18:42:05","TRTEDTM":"2022-02-19 15:27:41","TRT01SDTM":"2020-04-04 18:42:05","TRT01EDTM":"2021-02-19 09:27:41","TRT02SDTM":"2021-02-19 09:27:41","TRT02EDTM":"2022-02-19 15:27:41","AP01SDTM":"2020-04-04 18:42:05","AP01EDTM":"2021-02-19 09:27:41","AP02SDTM":"2021-02-19 09:27:41","AP02EDTM":"2022-02-19 15:27:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":686,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-19","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5554,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.96004,"AVALU":"U/L","BASE2":17.01821,"BASE":18.37357,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.05817,"PCHG2":-53.22635,"CHG":-10.41353,"PCHG":-56.67668,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-05 18:42:05","ADY":457,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-69","SUBJID":"id-69","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.54,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-01","TRTSDTM":"2020-04-04 18:42:05","TRTEDTM":"2022-02-19 15:27:41","TRT01SDTM":"2020-04-04 18:42:05","TRT01EDTM":"2021-02-19 09:27:41","TRT02SDTM":"2021-02-19 09:27:41","TRT02EDTM":"2022-02-19 15:27:41","AP01SDTM":"2020-04-04 18:42:05","AP01EDTM":"2021-02-19 09:27:41","AP02SDTM":"2021-02-19 09:27:41","AP02EDTM":"2022-02-19 15:27:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":686,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-19","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8055,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.39596,"AVALU":"U/L","BASE2":17.01821,"BASE":18.37357,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.37774,"PCHG2":13.97176,"CHG":1.02239,"PCHG":5.56446,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-14 18:42:05","ADY":650,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-69","SUBJID":"id-69","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.54,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-01","TRTSDTM":"2020-04-04 18:42:05","TRTEDTM":"2022-02-19 15:27:41","TRT01SDTM":"2020-04-04 18:42:05","TRT01EDTM":"2021-02-19 09:27:41","TRT02SDTM":"2021-02-19 09:27:41","TRT02EDTM":"2022-02-19 15:27:41","AP01SDTM":"2020-04-04 18:42:05","AP01EDTM":"2021-02-19 09:27:41","AP02SDTM":"2021-02-19 09:27:41","AP02EDTM":"2022-02-19 15:27:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":686,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-19","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7788,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.21069,"AVALU":"U/L","BASE2":17.01821,"BASE":18.37357,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.19247,"PCHG2":89.27185,"CHG":13.83712,"PCHG":75.30994,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-08 18:42:05","ADY":675,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-69","SUBJID":"id-69","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.54,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-01","TRTSDTM":"2020-04-04 18:42:05","TRTEDTM":"2022-02-19 15:27:41","TRT01SDTM":"2020-04-04 18:42:05","TRT01EDTM":"2021-02-19 09:27:41","TRT02SDTM":"2021-02-19 09:27:41","TRT02EDTM":"2022-02-19 15:27:41","AP01SDTM":"2020-04-04 18:42:05","AP01EDTM":"2021-02-19 09:27:41","AP02SDTM":"2021-02-19 09:27:41","AP02EDTM":"2022-02-19 15:27:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":686,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-19","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5117,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.31382,"AVALU":"mg/L","BASE2":9.31382,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-08-26 18:42:05","ADY":144,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-69","SUBJID":"id-69","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.54,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-01","TRTSDTM":"2020-04-04 18:42:05","TRTEDTM":"2022-02-19 15:27:41","TRT01SDTM":"2020-04-04 18:42:05","TRT01EDTM":"2021-02-19 09:27:41","TRT02SDTM":"2021-02-19 09:27:41","TRT02EDTM":"2022-02-19 15:27:41","AP01SDTM":"2020-04-04 18:42:05","AP01EDTM":"2021-02-19 09:27:41","AP02SDTM":"2021-02-19 09:27:41","AP02EDTM":"2022-02-19 15:27:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":686,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-19","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":460,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.10138,"AVALU":"mg/L","BASE2":9.31382,"BASE":10.10138,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.78756,"PCHG2":8.45578,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2020-09-08 18:42:05","ADY":157,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-69","SUBJID":"id-69","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.54,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-01","TRTSDTM":"2020-04-04 18:42:05","TRTEDTM":"2022-02-19 15:27:41","TRT01SDTM":"2020-04-04 18:42:05","TRT01EDTM":"2021-02-19 09:27:41","TRT02SDTM":"2021-02-19 09:27:41","TRT02EDTM":"2022-02-19 15:27:41","AP01SDTM":"2020-04-04 18:42:05","AP01EDTM":"2021-02-19 09:27:41","AP02SDTM":"2021-02-19 09:27:41","AP02EDTM":"2022-02-19 15:27:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":686,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-19","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4002,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.8896,"AVALU":"mg/L","BASE2":9.31382,"BASE":10.10138,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.57578,"PCHG2":6.18204,"CHG":-0.21177,"PCHG":-2.09646,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-10-01 18:42:05","ADY":180,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-69","SUBJID":"id-69","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.54,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-01","TRTSDTM":"2020-04-04 18:42:05","TRTEDTM":"2022-02-19 15:27:41","TRT01SDTM":"2020-04-04 18:42:05","TRT01EDTM":"2021-02-19 09:27:41","TRT02SDTM":"2021-02-19 09:27:41","TRT02EDTM":"2022-02-19 15:27:41","AP01SDTM":"2020-04-04 18:42:05","AP01EDTM":"2021-02-19 09:27:41","AP02SDTM":"2021-02-19 09:27:41","AP02EDTM":"2022-02-19 15:27:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":686,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-19","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2413,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.10865,"AVALU":"mg/L","BASE2":9.31382,"BASE":10.10138,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20517,"PCHG2":-2.20282,"CHG":-0.99272,"PCHG":-9.8276,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-12-06 18:42:05","ADY":246,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-69","SUBJID":"id-69","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.54,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-01","TRTSDTM":"2020-04-04 18:42:05","TRTEDTM":"2022-02-19 15:27:41","TRT01SDTM":"2020-04-04 18:42:05","TRT01EDTM":"2021-02-19 09:27:41","TRT02SDTM":"2021-02-19 09:27:41","TRT02EDTM":"2022-02-19 15:27:41","AP01SDTM":"2020-04-04 18:42:05","AP01EDTM":"2021-02-19 09:27:41","AP02SDTM":"2021-02-19 09:27:41","AP02EDTM":"2022-02-19 15:27:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":686,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-19","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8116,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.45597,"AVALU":"mg/L","BASE2":9.31382,"BASE":10.10138,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14215,"PCHG2":1.5262,"CHG":-0.64541,"PCHG":-6.38931,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-07-05 18:42:05","ADY":457,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-69","SUBJID":"id-69","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.54,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-01","TRTSDTM":"2020-04-04 18:42:05","TRTEDTM":"2022-02-19 15:27:41","TRT01SDTM":"2020-04-04 18:42:05","TRT01EDTM":"2021-02-19 09:27:41","TRT02SDTM":"2021-02-19 09:27:41","TRT02EDTM":"2022-02-19 15:27:41","AP01SDTM":"2020-04-04 18:42:05","AP01EDTM":"2021-02-19 09:27:41","AP02SDTM":"2021-02-19 09:27:41","AP02EDTM":"2022-02-19 15:27:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":686,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-19","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4840,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.5145,"AVALU":"mg/L","BASE2":9.31382,"BASE":10.10138,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.20068,"PCHG2":2.15469,"CHG":-0.58687,"PCHG":-5.80982,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-01-14 18:42:05","ADY":650,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-69","SUBJID":"id-69","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.54,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-01","TRTSDTM":"2020-04-04 18:42:05","TRTEDTM":"2022-02-19 15:27:41","TRT01SDTM":"2020-04-04 18:42:05","TRT01EDTM":"2021-02-19 09:27:41","TRT02SDTM":"2021-02-19 09:27:41","TRT02EDTM":"2022-02-19 15:27:41","AP01SDTM":"2020-04-04 18:42:05","AP01EDTM":"2021-02-19 09:27:41","AP02SDTM":"2021-02-19 09:27:41","AP02EDTM":"2022-02-19 15:27:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":686,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-19","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5216,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.80076,"AVALU":"mg/L","BASE2":9.31382,"BASE":10.10138,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.51306,"PCHG2":-5.50864,"CHG":-1.30062,"PCHG":-12.87568,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-02-08 18:42:05","ADY":675,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-69","SUBJID":"id-69","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.54,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-01","TRTSDTM":"2020-04-04 18:42:05","TRTEDTM":"2022-02-19 15:27:41","TRT01SDTM":"2020-04-04 18:42:05","TRT01EDTM":"2021-02-19 09:27:41","TRT02SDTM":"2021-02-19 09:27:41","TRT02EDTM":"2022-02-19 15:27:41","AP01SDTM":"2020-04-04 18:42:05","AP01EDTM":"2021-02-19 09:27:41","AP02SDTM":"2021-02-19 09:27:41","AP02EDTM":"2022-02-19 15:27:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":686,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-19","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1157,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90039,"AVALU":"g/L","BASE2":2.90039,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-26 18:42:05","ADY":144,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-69","SUBJID":"id-69","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.54,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-01","TRTSDTM":"2020-04-04 18:42:05","TRTEDTM":"2022-02-19 15:27:41","TRT01SDTM":"2020-04-04 18:42:05","TRT01EDTM":"2021-02-19 09:27:41","TRT02SDTM":"2021-02-19 09:27:41","TRT02EDTM":"2022-02-19 15:27:41","AP01SDTM":"2020-04-04 18:42:05","AP01EDTM":"2021-02-19 09:27:41","AP02SDTM":"2021-02-19 09:27:41","AP02EDTM":"2022-02-19 15:27:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":686,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-19","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5357,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84782,"AVALU":"g/L","BASE2":2.90039,"BASE":2.84782,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.05257,"PCHG2":-1.81256,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-08 18:42:05","ADY":157,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-69","SUBJID":"id-69","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.54,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-01","TRTSDTM":"2020-04-04 18:42:05","TRTEDTM":"2022-02-19 15:27:41","TRT01SDTM":"2020-04-04 18:42:05","TRT01EDTM":"2021-02-19 09:27:41","TRT02SDTM":"2021-02-19 09:27:41","TRT02EDTM":"2022-02-19 15:27:41","AP01SDTM":"2020-04-04 18:42:05","AP01EDTM":"2021-02-19 09:27:41","AP02SDTM":"2021-02-19 09:27:41","AP02EDTM":"2022-02-19 15:27:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":686,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-19","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7319,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95136,"AVALU":"g/L","BASE2":2.90039,"BASE":2.84782,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05097,"PCHG2":1.7574,"CHG":0.10354,"PCHG":3.63587,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-01 18:42:05","ADY":180,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-69","SUBJID":"id-69","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.54,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-01","TRTSDTM":"2020-04-04 18:42:05","TRTEDTM":"2022-02-19 15:27:41","TRT01SDTM":"2020-04-04 18:42:05","TRT01EDTM":"2021-02-19 09:27:41","TRT02SDTM":"2021-02-19 09:27:41","TRT02EDTM":"2022-02-19 15:27:41","AP01SDTM":"2020-04-04 18:42:05","AP01EDTM":"2021-02-19 09:27:41","AP02SDTM":"2021-02-19 09:27:41","AP02EDTM":"2022-02-19 15:27:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":686,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-19","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4540,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8969,"AVALU":"g/L","BASE2":2.90039,"BASE":2.84782,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00349,"PCHG2":-0.12027,"CHG":0.04908,"PCHG":1.72353,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-06 18:42:05","ADY":246,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-69","SUBJID":"id-69","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.54,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-01","TRTSDTM":"2020-04-04 18:42:05","TRTEDTM":"2022-02-19 15:27:41","TRT01SDTM":"2020-04-04 18:42:05","TRT01EDTM":"2021-02-19 09:27:41","TRT02SDTM":"2021-02-19 09:27:41","TRT02EDTM":"2022-02-19 15:27:41","AP01SDTM":"2020-04-04 18:42:05","AP01EDTM":"2021-02-19 09:27:41","AP02SDTM":"2021-02-19 09:27:41","AP02EDTM":"2022-02-19 15:27:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":686,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-19","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4186,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80809,"AVALU":"g/L","BASE2":2.90039,"BASE":2.84782,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0923,"PCHG2":-3.18233,"CHG":-0.03973,"PCHG":-1.39505,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-05 18:42:05","ADY":457,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-69","SUBJID":"id-69","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.54,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-01","TRTSDTM":"2020-04-04 18:42:05","TRTEDTM":"2022-02-19 15:27:41","TRT01SDTM":"2020-04-04 18:42:05","TRT01EDTM":"2021-02-19 09:27:41","TRT02SDTM":"2021-02-19 09:27:41","TRT02EDTM":"2022-02-19 15:27:41","AP01SDTM":"2020-04-04 18:42:05","AP01EDTM":"2021-02-19 09:27:41","AP02SDTM":"2021-02-19 09:27:41","AP02EDTM":"2022-02-19 15:27:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":686,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-19","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7426,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9423,"AVALU":"g/L","BASE2":2.90039,"BASE":2.84782,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04191,"PCHG2":1.44508,"CHG":0.09448,"PCHG":3.31778,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-14 18:42:05","ADY":650,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-69","SUBJID":"id-69","SITEID":"CHN-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.54,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-01","TRTSDTM":"2020-04-04 18:42:05","TRTEDTM":"2022-02-19 15:27:41","TRT01SDTM":"2020-04-04 18:42:05","TRT01EDTM":"2021-02-19 09:27:41","TRT02SDTM":"2021-02-19 09:27:41","TRT02EDTM":"2022-02-19 15:27:41","AP01SDTM":"2020-04-04 18:42:05","AP01EDTM":"2021-02-19 09:27:41","AP02SDTM":"2021-02-19 09:27:41","AP02EDTM":"2022-02-19 15:27:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":686,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-19","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6548,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79186,"AVALU":"g/L","BASE2":2.90039,"BASE":2.84782,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10853,"PCHG2":-3.74182,"CHG":-0.05596,"PCHG":-1.96487,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-08 18:42:05","ADY":675,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-71","SUBJID":"id-71","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.70143,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-21","TRTSDTM":"2020-12-24 12:35:40","TRTEDTM":"2023-12-25 06:35:40","TRT01SDTM":"2020-12-24 12:35:40","TRT01EDTM":"2022-12-25 00:35:40","TRT02SDTM":"2022-12-25 00:35:40","TRT02EDTM":"2023-12-25 06:35:40","AP01SDTM":"2020-12-24 12:35:40","AP01EDTM":"2022-12-25 00:35:40","AP02SDTM":"2022-12-25 00:35:40","AP02EDTM":"2023-12-25 06:35:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-25","EOSDY":1096,"LSTALVDT":"2024-01-10","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8038,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.31159,"AVALU":"U/L","BASE2":17.31159,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-13 12:35:40","ADY":201,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-71","SUBJID":"id-71","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.70143,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-21","TRTSDTM":"2020-12-24 12:35:40","TRTEDTM":"2023-12-25 06:35:40","TRT01SDTM":"2020-12-24 12:35:40","TRT01EDTM":"2022-12-25 00:35:40","TRT02SDTM":"2022-12-25 00:35:40","TRT02EDTM":"2023-12-25 06:35:40","AP01SDTM":"2020-12-24 12:35:40","AP01EDTM":"2022-12-25 00:35:40","AP02SDTM":"2022-12-25 00:35:40","AP02EDTM":"2023-12-25 06:35:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-25","EOSDY":1096,"LSTALVDT":"2024-01-10","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2012,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.67865,"AVALU":"U/L","BASE2":17.31159,"BASE":22.67865,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":5.36706,"PCHG2":31.00268,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-13 12:35:40","ADY":354,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-71","SUBJID":"id-71","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.70143,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-21","TRTSDTM":"2020-12-24 12:35:40","TRTEDTM":"2023-12-25 06:35:40","TRT01SDTM":"2020-12-24 12:35:40","TRT01EDTM":"2022-12-25 00:35:40","TRT02SDTM":"2022-12-25 00:35:40","TRT02EDTM":"2023-12-25 06:35:40","AP01SDTM":"2020-12-24 12:35:40","AP01EDTM":"2022-12-25 00:35:40","AP02SDTM":"2022-12-25 00:35:40","AP02EDTM":"2023-12-25 06:35:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-25","EOSDY":1096,"LSTALVDT":"2024-01-10","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3118,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.51022,"AVALU":"U/L","BASE2":17.31159,"BASE":22.67865,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.80137,"PCHG2":-16.18207,"CHG":-8.16843,"PCHG":-36.01816,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-14 12:35:40","ADY":537,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-71","SUBJID":"id-71","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.70143,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-21","TRTSDTM":"2020-12-24 12:35:40","TRTEDTM":"2023-12-25 06:35:40","TRT01SDTM":"2020-12-24 12:35:40","TRT01EDTM":"2022-12-25 00:35:40","TRT02SDTM":"2022-12-25 00:35:40","TRT02EDTM":"2023-12-25 06:35:40","AP01SDTM":"2020-12-24 12:35:40","AP01EDTM":"2022-12-25 00:35:40","AP02SDTM":"2022-12-25 00:35:40","AP02EDTM":"2023-12-25 06:35:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-25","EOSDY":1096,"LSTALVDT":"2024-01-10","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4789,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.10808,"AVALU":"U/L","BASE2":17.31159,"BASE":22.67865,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.79649,"PCHG2":4.60088,"CHG":-4.57057,"PCHG":-20.15363,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-29 12:35:40","ADY":705,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-71","SUBJID":"id-71","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.70143,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-21","TRTSDTM":"2020-12-24 12:35:40","TRTEDTM":"2023-12-25 06:35:40","TRT01SDTM":"2020-12-24 12:35:40","TRT01EDTM":"2022-12-25 00:35:40","TRT02SDTM":"2022-12-25 00:35:40","TRT02EDTM":"2023-12-25 06:35:40","AP01SDTM":"2020-12-24 12:35:40","AP01EDTM":"2022-12-25 00:35:40","AP02SDTM":"2022-12-25 00:35:40","AP02EDTM":"2023-12-25 06:35:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-25","EOSDY":1096,"LSTALVDT":"2024-01-10","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5695,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":40.84709,"AVALU":"U/L","BASE2":17.31159,"BASE":22.67865,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":23.5355,"PCHG2":135.95225,"CHG":18.16844,"PCHG":80.11253,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-30 12:35:40","ADY":767,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-71","SUBJID":"id-71","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.70143,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-21","TRTSDTM":"2020-12-24 12:35:40","TRTEDTM":"2023-12-25 06:35:40","TRT01SDTM":"2020-12-24 12:35:40","TRT01EDTM":"2022-12-25 00:35:40","TRT02SDTM":"2022-12-25 00:35:40","TRT02EDTM":"2023-12-25 06:35:40","AP01SDTM":"2020-12-24 12:35:40","AP01EDTM":"2022-12-25 00:35:40","AP02SDTM":"2022-12-25 00:35:40","AP02EDTM":"2023-12-25 06:35:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-25","EOSDY":1096,"LSTALVDT":"2024-01-10","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1690,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.9028,"AVALU":"U/L","BASE2":17.31159,"BASE":22.67865,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.59121,"PCHG2":14.96805,"CHG":-2.77585,"PCHG":-12.23993,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-13 12:35:40","ADY":931,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-71","SUBJID":"id-71","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.70143,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-21","TRTSDTM":"2020-12-24 12:35:40","TRTEDTM":"2023-12-25 06:35:40","TRT01SDTM":"2020-12-24 12:35:40","TRT01EDTM":"2022-12-25 00:35:40","TRT02SDTM":"2022-12-25 00:35:40","TRT02EDTM":"2023-12-25 06:35:40","AP01SDTM":"2020-12-24 12:35:40","AP01EDTM":"2022-12-25 00:35:40","AP02SDTM":"2022-12-25 00:35:40","AP02EDTM":"2023-12-25 06:35:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-25","EOSDY":1096,"LSTALVDT":"2024-01-10","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7044,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.75793,"AVALU":"U/L","BASE2":17.31159,"BASE":22.67865,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.44634,"PCHG2":14.13122,"CHG":-2.92072,"PCHG":-12.87872,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-11-17 12:35:40","ADY":1058,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-71","SUBJID":"id-71","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.70143,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-21","TRTSDTM":"2020-12-24 12:35:40","TRTEDTM":"2023-12-25 06:35:40","TRT01SDTM":"2020-12-24 12:35:40","TRT01EDTM":"2022-12-25 00:35:40","TRT02SDTM":"2022-12-25 00:35:40","TRT02EDTM":"2023-12-25 06:35:40","AP01SDTM":"2020-12-24 12:35:40","AP01EDTM":"2022-12-25 00:35:40","AP02SDTM":"2022-12-25 00:35:40","AP02EDTM":"2023-12-25 06:35:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-25","EOSDY":1096,"LSTALVDT":"2024-01-10","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3563,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.80204,"AVALU":"mg/L","BASE2":8.80204,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-13 12:35:40","ADY":201,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-71","SUBJID":"id-71","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.70143,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-21","TRTSDTM":"2020-12-24 12:35:40","TRTEDTM":"2023-12-25 06:35:40","TRT01SDTM":"2020-12-24 12:35:40","TRT01EDTM":"2022-12-25 00:35:40","TRT02SDTM":"2022-12-25 00:35:40","TRT02EDTM":"2023-12-25 06:35:40","AP01SDTM":"2020-12-24 12:35:40","AP01EDTM":"2022-12-25 00:35:40","AP02SDTM":"2022-12-25 00:35:40","AP02EDTM":"2023-12-25 06:35:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-25","EOSDY":1096,"LSTALVDT":"2024-01-10","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3717,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.19963,"AVALU":"mg/L","BASE2":8.80204,"BASE":9.19963,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.39759,"PCHG2":4.51705,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-13 12:35:40","ADY":354,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-71","SUBJID":"id-71","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.70143,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-21","TRTSDTM":"2020-12-24 12:35:40","TRTEDTM":"2023-12-25 06:35:40","TRT01SDTM":"2020-12-24 12:35:40","TRT01EDTM":"2022-12-25 00:35:40","TRT02SDTM":"2022-12-25 00:35:40","TRT02EDTM":"2023-12-25 06:35:40","AP01SDTM":"2020-12-24 12:35:40","AP01EDTM":"2022-12-25 00:35:40","AP02SDTM":"2022-12-25 00:35:40","AP02EDTM":"2023-12-25 06:35:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-25","EOSDY":1096,"LSTALVDT":"2024-01-10","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7048,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.59417,"AVALU":"mg/L","BASE2":8.80204,"BASE":9.19963,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20787,"PCHG2":-2.36156,"CHG":-0.60546,"PCHG":-6.58133,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-14 12:35:40","ADY":537,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-71","SUBJID":"id-71","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.70143,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-21","TRTSDTM":"2020-12-24 12:35:40","TRTEDTM":"2023-12-25 06:35:40","TRT01SDTM":"2020-12-24 12:35:40","TRT01EDTM":"2022-12-25 00:35:40","TRT02SDTM":"2022-12-25 00:35:40","TRT02EDTM":"2023-12-25 06:35:40","AP01SDTM":"2020-12-24 12:35:40","AP01EDTM":"2022-12-25 00:35:40","AP02SDTM":"2022-12-25 00:35:40","AP02EDTM":"2023-12-25 06:35:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-25","EOSDY":1096,"LSTALVDT":"2024-01-10","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4177,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.38646,"AVALU":"mg/L","BASE2":8.80204,"BASE":9.19963,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.58442,"PCHG2":6.63958,"CHG":0.18683,"PCHG":2.0308,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-29 12:35:40","ADY":705,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-71","SUBJID":"id-71","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.70143,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-21","TRTSDTM":"2020-12-24 12:35:40","TRTEDTM":"2023-12-25 06:35:40","TRT01SDTM":"2020-12-24 12:35:40","TRT01EDTM":"2022-12-25 00:35:40","TRT02SDTM":"2022-12-25 00:35:40","TRT02EDTM":"2023-12-25 06:35:40","AP01SDTM":"2020-12-24 12:35:40","AP01EDTM":"2022-12-25 00:35:40","AP02SDTM":"2022-12-25 00:35:40","AP02EDTM":"2023-12-25 06:35:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-25","EOSDY":1096,"LSTALVDT":"2024-01-10","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4461,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.14532,"AVALU":"mg/L","BASE2":8.80204,"BASE":9.19963,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.65671,"PCHG2":-7.46094,"CHG":-1.05431,"PCHG":-11.46032,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-30 12:35:40","ADY":767,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-71","SUBJID":"id-71","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.70143,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-21","TRTSDTM":"2020-12-24 12:35:40","TRTEDTM":"2023-12-25 06:35:40","TRT01SDTM":"2020-12-24 12:35:40","TRT01EDTM":"2022-12-25 00:35:40","TRT02SDTM":"2022-12-25 00:35:40","TRT02EDTM":"2023-12-25 06:35:40","AP01SDTM":"2020-12-24 12:35:40","AP01EDTM":"2022-12-25 00:35:40","AP02SDTM":"2022-12-25 00:35:40","AP02EDTM":"2023-12-25 06:35:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-25","EOSDY":1096,"LSTALVDT":"2024-01-10","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3312,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.28175,"AVALU":"mg/L","BASE2":8.80204,"BASE":9.19963,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.47972,"PCHG2":16.81107,"CHG":1.08212,"PCHG":11.76269,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2023-07-13 12:35:40","ADY":931,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-71","SUBJID":"id-71","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.70143,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-21","TRTSDTM":"2020-12-24 12:35:40","TRTEDTM":"2023-12-25 06:35:40","TRT01SDTM":"2020-12-24 12:35:40","TRT01EDTM":"2022-12-25 00:35:40","TRT02SDTM":"2022-12-25 00:35:40","TRT02EDTM":"2023-12-25 06:35:40","AP01SDTM":"2020-12-24 12:35:40","AP01EDTM":"2022-12-25 00:35:40","AP02SDTM":"2022-12-25 00:35:40","AP02EDTM":"2023-12-25 06:35:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-25","EOSDY":1096,"LSTALVDT":"2024-01-10","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6187,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.41806,"AVALU":"mg/L","BASE2":8.80204,"BASE":9.19963,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.61602,"PCHG2":6.99862,"CHG":0.21843,"PCHG":2.37432,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-11-17 12:35:40","ADY":1058,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-71","SUBJID":"id-71","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.70143,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-21","TRTSDTM":"2020-12-24 12:35:40","TRTEDTM":"2023-12-25 06:35:40","TRT01SDTM":"2020-12-24 12:35:40","TRT01EDTM":"2022-12-25 00:35:40","TRT02SDTM":"2022-12-25 00:35:40","TRT02EDTM":"2023-12-25 06:35:40","AP01SDTM":"2020-12-24 12:35:40","AP01EDTM":"2022-12-25 00:35:40","AP02SDTM":"2022-12-25 00:35:40","AP02EDTM":"2023-12-25 06:35:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-25","EOSDY":1096,"LSTALVDT":"2024-01-10","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7677,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88319,"AVALU":"g/L","BASE2":2.88319,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-13 12:35:40","ADY":201,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-71","SUBJID":"id-71","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.70143,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-21","TRTSDTM":"2020-12-24 12:35:40","TRTEDTM":"2023-12-25 06:35:40","TRT01SDTM":"2020-12-24 12:35:40","TRT01EDTM":"2022-12-25 00:35:40","TRT02SDTM":"2022-12-25 00:35:40","TRT02EDTM":"2023-12-25 06:35:40","AP01SDTM":"2020-12-24 12:35:40","AP01EDTM":"2022-12-25 00:35:40","AP02SDTM":"2022-12-25 00:35:40","AP02EDTM":"2023-12-25 06:35:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-25","EOSDY":1096,"LSTALVDT":"2024-01-10","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":685,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94418,"AVALU":"g/L","BASE2":2.88319,"BASE":2.94418,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.06099,"PCHG2":2.11528,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-13 12:35:40","ADY":354,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-71","SUBJID":"id-71","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.70143,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-21","TRTSDTM":"2020-12-24 12:35:40","TRTEDTM":"2023-12-25 06:35:40","TRT01SDTM":"2020-12-24 12:35:40","TRT01EDTM":"2022-12-25 00:35:40","TRT02SDTM":"2022-12-25 00:35:40","TRT02EDTM":"2023-12-25 06:35:40","AP01SDTM":"2020-12-24 12:35:40","AP01EDTM":"2022-12-25 00:35:40","AP02SDTM":"2022-12-25 00:35:40","AP02EDTM":"2023-12-25 06:35:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-25","EOSDY":1096,"LSTALVDT":"2024-01-10","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7375,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95456,"AVALU":"g/L","BASE2":2.88319,"BASE":2.94418,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07137,"PCHG2":2.47546,"CHG":0.01038,"PCHG":0.35272,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-14 12:35:40","ADY":537,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-71","SUBJID":"id-71","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.70143,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-21","TRTSDTM":"2020-12-24 12:35:40","TRTEDTM":"2023-12-25 06:35:40","TRT01SDTM":"2020-12-24 12:35:40","TRT01EDTM":"2022-12-25 00:35:40","TRT02SDTM":"2022-12-25 00:35:40","TRT02EDTM":"2023-12-25 06:35:40","AP01SDTM":"2020-12-24 12:35:40","AP01EDTM":"2022-12-25 00:35:40","AP02SDTM":"2022-12-25 00:35:40","AP02EDTM":"2023-12-25 06:35:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-25","EOSDY":1096,"LSTALVDT":"2024-01-10","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4372,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88536,"AVALU":"g/L","BASE2":2.88319,"BASE":2.94418,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00217,"PCHG2":0.07536,"CHG":-0.05881,"PCHG":-1.99766,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-29 12:35:40","ADY":705,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-71","SUBJID":"id-71","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.70143,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-21","TRTSDTM":"2020-12-24 12:35:40","TRTEDTM":"2023-12-25 06:35:40","TRT01SDTM":"2020-12-24 12:35:40","TRT01EDTM":"2022-12-25 00:35:40","TRT02SDTM":"2022-12-25 00:35:40","TRT02EDTM":"2023-12-25 06:35:40","AP01SDTM":"2020-12-24 12:35:40","AP01EDTM":"2022-12-25 00:35:40","AP02SDTM":"2022-12-25 00:35:40","AP02EDTM":"2023-12-25 06:35:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-25","EOSDY":1096,"LSTALVDT":"2024-01-10","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7463,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87597,"AVALU":"g/L","BASE2":2.88319,"BASE":2.94418,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00722,"PCHG2":-0.25028,"CHG":-0.0682,"PCHG":-2.31656,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-30 12:35:40","ADY":767,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-71","SUBJID":"id-71","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.70143,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-21","TRTSDTM":"2020-12-24 12:35:40","TRTEDTM":"2023-12-25 06:35:40","TRT01SDTM":"2020-12-24 12:35:40","TRT01EDTM":"2022-12-25 00:35:40","TRT02SDTM":"2022-12-25 00:35:40","TRT02EDTM":"2023-12-25 06:35:40","AP01SDTM":"2020-12-24 12:35:40","AP01EDTM":"2022-12-25 00:35:40","AP02SDTM":"2022-12-25 00:35:40","AP02EDTM":"2023-12-25 06:35:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-25","EOSDY":1096,"LSTALVDT":"2024-01-10","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3636,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9784,"AVALU":"g/L","BASE2":2.88319,"BASE":2.94418,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09521,"PCHG2":3.30227,"CHG":0.03422,"PCHG":1.1624,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-13 12:35:40","ADY":931,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-71","SUBJID":"id-71","SITEID":"CHN-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":7.70143,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-21","TRTSDTM":"2020-12-24 12:35:40","TRTEDTM":"2023-12-25 06:35:40","TRT01SDTM":"2020-12-24 12:35:40","TRT01EDTM":"2022-12-25 00:35:40","TRT02SDTM":"2022-12-25 00:35:40","TRT02EDTM":"2023-12-25 06:35:40","AP01SDTM":"2020-12-24 12:35:40","AP01EDTM":"2022-12-25 00:35:40","AP02SDTM":"2022-12-25 00:35:40","AP02EDTM":"2023-12-25 06:35:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-25","EOSDY":1096,"LSTALVDT":"2024-01-10","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2537,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82513,"AVALU":"g/L","BASE2":2.88319,"BASE":2.94418,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05806,"PCHG2":-2.01389,"CHG":-0.11905,"PCHG":-4.04363,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-11-17 12:35:40","ADY":1058,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-74","SUBJID":"id-74","SITEID":"CHN-1","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.80318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-18","TRTSDTM":"2020-01-18 04:01:51","TRT01SDTM":"2020-01-18 04:01:51","AP01SDTM":"2020-01-18 04:01:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4892,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.83896,"AVALU":"U/L","BASE2":27.83896,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-4","ADTM":"2020-01-31 04:01:51","ADY":13,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-74","SUBJID":"id-74","SITEID":"CHN-1","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.80318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-18","TRTSDTM":"2020-01-18 04:01:51","TRT01SDTM":"2020-01-18 04:01:51","AP01SDTM":"2020-01-18 04:01:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3658,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.79899,"AVALU":"U/L","BASE2":27.83896,"BASE":5.79899,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-22.03997,"PCHG2":-79.16952,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-4","BTOXGR":"-4","ADTM":"2020-04-18 04:01:51","ADY":91,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-74","SUBJID":"id-74","SITEID":"CHN-1","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.80318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-18","TRTSDTM":"2020-01-18 04:01:51","TRT01SDTM":"2020-01-18 04:01:51","AP01SDTM":"2020-01-18 04:01:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2978,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.26046,"AVALU":"U/L","BASE2":27.83896,"BASE":5.79899,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.5785,"PCHG2":-30.81472,"CHG":13.46147,"PCHG":232.1348,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2020-06-20 04:01:51","ADY":154,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-74","SUBJID":"id-74","SITEID":"CHN-1","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.80318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-18","TRTSDTM":"2020-01-18 04:01:51","TRT01SDTM":"2020-01-18 04:01:51","AP01SDTM":"2020-01-18 04:01:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":283,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.22652,"AVALU":"U/L","BASE2":27.83896,"BASE":5.79899,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.61244,"PCHG2":-30.93665,"CHG":13.42753,"PCHG":231.54945,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2020-07-28 04:01:51","ADY":192,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-74","SUBJID":"id-74","SITEID":"CHN-1","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.80318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-18","TRTSDTM":"2020-01-18 04:01:51","TRT01SDTM":"2020-01-18 04:01:51","AP01SDTM":"2020-01-18 04:01:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6080,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.1026,"AVALU":"U/L","BASE2":27.83896,"BASE":5.79899,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.26365,"PCHG2":8.13122,"CHG":24.30361,"PCHG":419.10085,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2020-12-03 04:01:51","ADY":320,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-74","SUBJID":"id-74","SITEID":"CHN-1","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.80318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-18","TRTSDTM":"2020-01-18 04:01:51","TRT01SDTM":"2020-01-18 04:01:51","AP01SDTM":"2020-01-18 04:01:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8300,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.04093,"AVALU":"U/L","BASE2":27.83896,"BASE":5.79899,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.79803,"PCHG2":-60.34001,"CHG":5.24194,"PCHG":90.39398,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-07-15 04:01:51","ADY":544,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-74","SUBJID":"id-74","SITEID":"CHN-1","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.80318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-18","TRTSDTM":"2020-01-18 04:01:51","TRT01SDTM":"2020-01-18 04:01:51","AP01SDTM":"2020-01-18 04:01:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4561,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.59211,"AVALU":"U/L","BASE2":27.83896,"BASE":5.79899,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.24685,"PCHG2":-33.21549,"CHG":12.79312,"PCHG":220.6095,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-12-10 04:01:51","ADY":692,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-74","SUBJID":"id-74","SITEID":"CHN-1","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.80318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-18","TRTSDTM":"2020-01-18 04:01:51","TRT01SDTM":"2020-01-18 04:01:51","AP01SDTM":"2020-01-18 04:01:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5587,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.22891,"AVALU":"mg/L","BASE2":9.22891,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-31 04:01:51","ADY":13,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-74","SUBJID":"id-74","SITEID":"CHN-1","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.80318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-18","TRTSDTM":"2020-01-18 04:01:51","TRT01SDTM":"2020-01-18 04:01:51","AP01SDTM":"2020-01-18 04:01:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5692,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.82561,"AVALU":"mg/L","BASE2":9.22891,"BASE":9.82561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.5967,"PCHG2":6.46551,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-18 04:01:51","ADY":91,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-74","SUBJID":"id-74","SITEID":"CHN-1","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.80318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-18","TRTSDTM":"2020-01-18 04:01:51","TRT01SDTM":"2020-01-18 04:01:51","AP01SDTM":"2020-01-18 04:01:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6370,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.27828,"AVALU":"mg/L","BASE2":9.22891,"BASE":9.82561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.95064,"PCHG2":-10.30063,"CHG":-1.54733,"PCHG":-15.74795,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-20 04:01:51","ADY":154,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-74","SUBJID":"id-74","SITEID":"CHN-1","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.80318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-18","TRTSDTM":"2020-01-18 04:01:51","TRT01SDTM":"2020-01-18 04:01:51","AP01SDTM":"2020-01-18 04:01:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":719,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.41337,"AVALU":"mg/L","BASE2":9.22891,"BASE":9.82561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.18446,"PCHG2":12.83421,"CHG":0.58776,"PCHG":5.98194,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-07-28 04:01:51","ADY":192,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-74","SUBJID":"id-74","SITEID":"CHN-1","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.80318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-18","TRTSDTM":"2020-01-18 04:01:51","TRT01SDTM":"2020-01-18 04:01:51","AP01SDTM":"2020-01-18 04:01:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":439,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.67129,"AVALU":"mg/L","BASE2":9.22891,"BASE":9.82561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.44238,"PCHG2":15.6289,"CHG":0.84568,"PCHG":8.60692,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-12-03 04:01:51","ADY":320,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-74","SUBJID":"id-74","SITEID":"CHN-1","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.80318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-18","TRTSDTM":"2020-01-18 04:01:51","TRT01SDTM":"2020-01-18 04:01:51","AP01SDTM":"2020-01-18 04:01:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5098,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.38238,"AVALU":"mg/L","BASE2":9.22891,"BASE":9.82561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.15347,"PCHG2":23.33392,"CHG":1.55677,"PCHG":15.84402,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-07-15 04:01:51","ADY":544,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-74","SUBJID":"id-74","SITEID":"CHN-1","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.80318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-18","TRTSDTM":"2020-01-18 04:01:51","TRT01SDTM":"2020-01-18 04:01:51","AP01SDTM":"2020-01-18 04:01:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":435,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.45157,"AVALU":"mg/L","BASE2":9.22891,"BASE":9.82561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.22266,"PCHG2":2.41259,"CHG":-0.37404,"PCHG":-3.80679,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-10 04:01:51","ADY":692,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-74","SUBJID":"id-74","SITEID":"CHN-1","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.80318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-18","TRTSDTM":"2020-01-18 04:01:51","TRT01SDTM":"2020-01-18 04:01:51","AP01SDTM":"2020-01-18 04:01:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6391,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92798,"AVALU":"g/L","BASE2":2.92798,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-31 04:01:51","ADY":13,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-74","SUBJID":"id-74","SITEID":"CHN-1","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.80318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-18","TRTSDTM":"2020-01-18 04:01:51","TRT01SDTM":"2020-01-18 04:01:51","AP01SDTM":"2020-01-18 04:01:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6691,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80886,"AVALU":"g/L","BASE2":2.92798,"BASE":2.80886,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.11911,"PCHG2":-4.06813,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-18 04:01:51","ADY":91,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-74","SUBJID":"id-74","SITEID":"CHN-1","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.80318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-18","TRTSDTM":"2020-01-18 04:01:51","TRT01SDTM":"2020-01-18 04:01:51","AP01SDTM":"2020-01-18 04:01:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4225,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98743,"AVALU":"g/L","BASE2":2.92798,"BASE":2.80886,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05945,"PCHG2":2.03047,"CHG":0.17857,"PCHG":6.35722,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-20 04:01:51","ADY":154,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-74","SUBJID":"id-74","SITEID":"CHN-1","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.80318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-18","TRTSDTM":"2020-01-18 04:01:51","TRT01SDTM":"2020-01-18 04:01:51","AP01SDTM":"2020-01-18 04:01:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7186,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89684,"AVALU":"g/L","BASE2":2.92798,"BASE":2.80886,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03113,"PCHG2":-1.06325,"CHG":0.08798,"PCHG":3.1323,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-28 04:01:51","ADY":192,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-74","SUBJID":"id-74","SITEID":"CHN-1","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.80318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-18","TRTSDTM":"2020-01-18 04:01:51","TRT01SDTM":"2020-01-18 04:01:51","AP01SDTM":"2020-01-18 04:01:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5741,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91257,"AVALU":"g/L","BASE2":2.92798,"BASE":2.80886,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0154,"PCHG2":-0.52606,"CHG":0.10371,"PCHG":3.69228,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-03 04:01:51","ADY":320,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-74","SUBJID":"id-74","SITEID":"CHN-1","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.80318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-18","TRTSDTM":"2020-01-18 04:01:51","TRT01SDTM":"2020-01-18 04:01:51","AP01SDTM":"2020-01-18 04:01:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7612,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98613,"AVALU":"g/L","BASE2":2.92798,"BASE":2.80886,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05815,"PCHG2":1.986,"CHG":0.17726,"PCHG":6.31086,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-15 04:01:51","ADY":544,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-74","SUBJID":"id-74","SITEID":"CHN-1","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.80318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-18","TRTSDTM":"2020-01-18 04:01:51","TRT01SDTM":"2020-01-18 04:01:51","AP01SDTM":"2020-01-18 04:01:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8216,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87628,"AVALU":"g/L","BASE2":2.92798,"BASE":2.80886,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0517,"PCHG2":-1.76573,"CHG":0.06741,"PCHG":2.40003,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-10 04:01:51","ADY":692,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-78","SUBJID":"id-78","SITEID":"CHN-1","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.74209,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-21 16:21:14","TRTEDTM":"2023-02-21 10:21:14","TRT01SDTM":"2020-02-21 16:21:14","TRT01EDTM":"2022-02-21 04:21:14","TRT02SDTM":"2022-02-21 04:21:14","TRT02EDTM":"2023-02-21 10:21:14","AP01SDTM":"2020-02-21 16:21:14","AP01EDTM":"2022-02-21 04:21:14","AP02SDTM":"2022-02-21 04:21:14","AP02EDTM":"2023-02-21 10:21:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-21","EOSDY":1096,"LSTALVDT":"2023-03-06","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7790,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.88873,"AVALU":"U/L","BASE2":34.88873,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-23 16:21:14","ADY":153,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-78","SUBJID":"id-78","SITEID":"CHN-1","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.74209,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-21 16:21:14","TRTEDTM":"2023-02-21 10:21:14","TRT01SDTM":"2020-02-21 16:21:14","TRT01EDTM":"2022-02-21 04:21:14","TRT02SDTM":"2022-02-21 04:21:14","TRT02EDTM":"2023-02-21 10:21:14","AP01SDTM":"2020-02-21 16:21:14","AP01EDTM":"2022-02-21 04:21:14","AP02SDTM":"2022-02-21 04:21:14","AP02EDTM":"2023-02-21 10:21:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-21","EOSDY":1096,"LSTALVDT":"2023-03-06","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1854,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.78921,"AVALU":"U/L","BASE2":34.88873,"BASE":19.78921,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-15.09952,"PCHG2":-43.27908,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-02 16:21:14","ADY":224,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-78","SUBJID":"id-78","SITEID":"CHN-1","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.74209,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-21 16:21:14","TRTEDTM":"2023-02-21 10:21:14","TRT01SDTM":"2020-02-21 16:21:14","TRT01EDTM":"2022-02-21 04:21:14","TRT02SDTM":"2022-02-21 04:21:14","TRT02EDTM":"2023-02-21 10:21:14","AP01SDTM":"2020-02-21 16:21:14","AP01EDTM":"2022-02-21 04:21:14","AP02SDTM":"2022-02-21 04:21:14","AP02EDTM":"2023-02-21 10:21:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-21","EOSDY":1096,"LSTALVDT":"2023-03-06","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5165,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.87855,"AVALU":"U/L","BASE2":34.88873,"BASE":19.78921,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.01018,"PCHG2":-25.82547,"CHG":6.08934,"PCHG":30.77102,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-24 16:21:14","ADY":489,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-78","SUBJID":"id-78","SITEID":"CHN-1","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.74209,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-21 16:21:14","TRTEDTM":"2023-02-21 10:21:14","TRT01SDTM":"2020-02-21 16:21:14","TRT01EDTM":"2022-02-21 04:21:14","TRT02SDTM":"2022-02-21 04:21:14","TRT02EDTM":"2023-02-21 10:21:14","AP01SDTM":"2020-02-21 16:21:14","AP01EDTM":"2022-02-21 04:21:14","AP02SDTM":"2022-02-21 04:21:14","AP02EDTM":"2023-02-21 10:21:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-21","EOSDY":1096,"LSTALVDT":"2023-03-06","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5875,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.533,"AVALU":"U/L","BASE2":34.88873,"BASE":19.78921,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-19.35574,"PCHG2":-55.47847,"CHG":-4.25621,"PCHG":-21.50775,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-06 16:21:14","ADY":532,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-78","SUBJID":"id-78","SITEID":"CHN-1","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.74209,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-21 16:21:14","TRTEDTM":"2023-02-21 10:21:14","TRT01SDTM":"2020-02-21 16:21:14","TRT01EDTM":"2022-02-21 04:21:14","TRT02SDTM":"2022-02-21 04:21:14","TRT02EDTM":"2023-02-21 10:21:14","AP01SDTM":"2020-02-21 16:21:14","AP01EDTM":"2022-02-21 04:21:14","AP02SDTM":"2022-02-21 04:21:14","AP02EDTM":"2023-02-21 10:21:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-21","EOSDY":1096,"LSTALVDT":"2023-03-06","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7041,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.29141,"AVALU":"U/L","BASE2":34.88873,"BASE":19.78921,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.59732,"PCHG2":-30.37462,"CHG":4.5022,"PCHG":22.75079,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-28 16:21:14","ADY":646,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-78","SUBJID":"id-78","SITEID":"CHN-1","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.74209,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-21 16:21:14","TRTEDTM":"2023-02-21 10:21:14","TRT01SDTM":"2020-02-21 16:21:14","TRT01EDTM":"2022-02-21 04:21:14","TRT02SDTM":"2022-02-21 04:21:14","TRT02EDTM":"2023-02-21 10:21:14","AP01SDTM":"2020-02-21 16:21:14","AP01EDTM":"2022-02-21 04:21:14","AP02SDTM":"2022-02-21 04:21:14","AP02EDTM":"2023-02-21 10:21:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-21","EOSDY":1096,"LSTALVDT":"2023-03-06","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1014,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.43341,"AVALU":"U/L","BASE2":34.88873,"BASE":19.78921,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-15.45532,"PCHG2":-44.29889,"CHG":-0.3558,"PCHG":-1.79793,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-10 16:21:14","ADY":689,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-78","SUBJID":"id-78","SITEID":"CHN-1","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.74209,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-21 16:21:14","TRTEDTM":"2023-02-21 10:21:14","TRT01SDTM":"2020-02-21 16:21:14","TRT01EDTM":"2022-02-21 04:21:14","TRT02SDTM":"2022-02-21 04:21:14","TRT02EDTM":"2023-02-21 10:21:14","AP01SDTM":"2020-02-21 16:21:14","AP01EDTM":"2022-02-21 04:21:14","AP02SDTM":"2022-02-21 04:21:14","AP02EDTM":"2023-02-21 10:21:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-21","EOSDY":1096,"LSTALVDT":"2023-03-06","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5081,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.45152,"AVALU":"U/L","BASE2":34.88873,"BASE":19.78921,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-31.43722,"PCHG2":-90.10708,"CHG":-16.33769,"PCHG":-82.5586,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-10-13 16:21:14","ADY":965,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-78","SUBJID":"id-78","SITEID":"CHN-1","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.74209,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-21 16:21:14","TRTEDTM":"2023-02-21 10:21:14","TRT01SDTM":"2020-02-21 16:21:14","TRT01EDTM":"2022-02-21 04:21:14","TRT02SDTM":"2022-02-21 04:21:14","TRT02EDTM":"2023-02-21 10:21:14","AP01SDTM":"2020-02-21 16:21:14","AP01EDTM":"2022-02-21 04:21:14","AP02SDTM":"2022-02-21 04:21:14","AP02EDTM":"2023-02-21 10:21:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-21","EOSDY":1096,"LSTALVDT":"2023-03-06","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3711,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.05377,"AVALU":"mg/L","BASE2":8.05377,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-23 16:21:14","ADY":153,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-78","SUBJID":"id-78","SITEID":"CHN-1","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.74209,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-21 16:21:14","TRTEDTM":"2023-02-21 10:21:14","TRT01SDTM":"2020-02-21 16:21:14","TRT01EDTM":"2022-02-21 04:21:14","TRT02SDTM":"2022-02-21 04:21:14","TRT02EDTM":"2023-02-21 10:21:14","AP01SDTM":"2020-02-21 16:21:14","AP01EDTM":"2022-02-21 04:21:14","AP02SDTM":"2022-02-21 04:21:14","AP02EDTM":"2023-02-21 10:21:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-21","EOSDY":1096,"LSTALVDT":"2023-03-06","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2204,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.37401,"AVALU":"mg/L","BASE2":8.05377,"BASE":8.37401,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.32024,"PCHG2":3.9763,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-02 16:21:14","ADY":224,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-78","SUBJID":"id-78","SITEID":"CHN-1","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.74209,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-21 16:21:14","TRTEDTM":"2023-02-21 10:21:14","TRT01SDTM":"2020-02-21 16:21:14","TRT01EDTM":"2022-02-21 04:21:14","TRT02SDTM":"2022-02-21 04:21:14","TRT02EDTM":"2023-02-21 10:21:14","AP01SDTM":"2020-02-21 16:21:14","AP01EDTM":"2022-02-21 04:21:14","AP02SDTM":"2022-02-21 04:21:14","AP02EDTM":"2023-02-21 10:21:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-21","EOSDY":1096,"LSTALVDT":"2023-03-06","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1861,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.4028,"AVALU":"mg/L","BASE2":8.05377,"BASE":8.37401,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.34903,"PCHG2":4.33378,"CHG":0.02879,"PCHG":0.3438,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-24 16:21:14","ADY":489,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-78","SUBJID":"id-78","SITEID":"CHN-1","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.74209,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-21 16:21:14","TRTEDTM":"2023-02-21 10:21:14","TRT01SDTM":"2020-02-21 16:21:14","TRT01EDTM":"2022-02-21 04:21:14","TRT02SDTM":"2022-02-21 04:21:14","TRT02EDTM":"2023-02-21 10:21:14","AP01SDTM":"2020-02-21 16:21:14","AP01EDTM":"2022-02-21 04:21:14","AP02SDTM":"2022-02-21 04:21:14","AP02EDTM":"2023-02-21 10:21:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-21","EOSDY":1096,"LSTALVDT":"2023-03-06","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1892,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.47547,"AVALU":"mg/L","BASE2":8.05377,"BASE":8.37401,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.4217,"PCHG2":17.65257,"CHG":1.10145,"PCHG":13.15325,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-06 16:21:14","ADY":532,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-78","SUBJID":"id-78","SITEID":"CHN-1","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.74209,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-21 16:21:14","TRTEDTM":"2023-02-21 10:21:14","TRT01SDTM":"2020-02-21 16:21:14","TRT01EDTM":"2022-02-21 04:21:14","TRT02SDTM":"2022-02-21 04:21:14","TRT02EDTM":"2023-02-21 10:21:14","AP01SDTM":"2020-02-21 16:21:14","AP01EDTM":"2022-02-21 04:21:14","AP02SDTM":"2022-02-21 04:21:14","AP02EDTM":"2023-02-21 10:21:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-21","EOSDY":1096,"LSTALVDT":"2023-03-06","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5481,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.51921,"AVALU":"mg/L","BASE2":8.05377,"BASE":8.37401,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.46544,"PCHG2":5.7791,"CHG":0.14519,"PCHG":1.73385,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-28 16:21:14","ADY":646,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-78","SUBJID":"id-78","SITEID":"CHN-1","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.74209,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-21 16:21:14","TRTEDTM":"2023-02-21 10:21:14","TRT01SDTM":"2020-02-21 16:21:14","TRT01EDTM":"2022-02-21 04:21:14","TRT02SDTM":"2022-02-21 04:21:14","TRT02EDTM":"2023-02-21 10:21:14","AP01SDTM":"2020-02-21 16:21:14","AP01EDTM":"2022-02-21 04:21:14","AP02SDTM":"2022-02-21 04:21:14","AP02EDTM":"2023-02-21 10:21:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-21","EOSDY":1096,"LSTALVDT":"2023-03-06","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":746,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.89328,"AVALU":"mg/L","BASE2":8.05377,"BASE":8.37401,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.83951,"PCHG2":10.42376,"CHG":0.51926,"PCHG":6.2009,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-10 16:21:14","ADY":689,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-78","SUBJID":"id-78","SITEID":"CHN-1","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.74209,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-21 16:21:14","TRTEDTM":"2023-02-21 10:21:14","TRT01SDTM":"2020-02-21 16:21:14","TRT01EDTM":"2022-02-21 04:21:14","TRT02SDTM":"2022-02-21 04:21:14","TRT02EDTM":"2023-02-21 10:21:14","AP01SDTM":"2020-02-21 16:21:14","AP01EDTM":"2022-02-21 04:21:14","AP02SDTM":"2022-02-21 04:21:14","AP02EDTM":"2023-02-21 10:21:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-21","EOSDY":1096,"LSTALVDT":"2023-03-06","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":982,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.92848,"AVALU":"mg/L","BASE2":8.05377,"BASE":8.37401,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.87471,"PCHG2":48.11052,"CHG":3.55447,"PCHG":42.44642,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-10-13 16:21:14","ADY":965,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-78","SUBJID":"id-78","SITEID":"CHN-1","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.74209,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-21 16:21:14","TRTEDTM":"2023-02-21 10:21:14","TRT01SDTM":"2020-02-21 16:21:14","TRT01EDTM":"2022-02-21 04:21:14","TRT02SDTM":"2022-02-21 04:21:14","TRT02EDTM":"2023-02-21 10:21:14","AP01SDTM":"2020-02-21 16:21:14","AP01EDTM":"2022-02-21 04:21:14","AP02SDTM":"2022-02-21 04:21:14","AP02EDTM":"2023-02-21 10:21:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-21","EOSDY":1096,"LSTALVDT":"2023-03-06","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":854,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05606,"AVALU":"g/L","BASE2":3.05606,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-07-23 16:21:14","ADY":153,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-78","SUBJID":"id-78","SITEID":"CHN-1","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.74209,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-21 16:21:14","TRTEDTM":"2023-02-21 10:21:14","TRT01SDTM":"2020-02-21 16:21:14","TRT01EDTM":"2022-02-21 04:21:14","TRT02SDTM":"2022-02-21 04:21:14","TRT02EDTM":"2023-02-21 10:21:14","AP01SDTM":"2020-02-21 16:21:14","AP01EDTM":"2022-02-21 04:21:14","AP02SDTM":"2022-02-21 04:21:14","AP02EDTM":"2023-02-21 10:21:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-21","EOSDY":1096,"LSTALVDT":"2023-03-06","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6589,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85455,"AVALU":"g/L","BASE2":3.05606,"BASE":2.85455,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.20151,"PCHG2":-6.59367,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-02 16:21:14","ADY":224,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-78","SUBJID":"id-78","SITEID":"CHN-1","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.74209,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-21 16:21:14","TRTEDTM":"2023-02-21 10:21:14","TRT01SDTM":"2020-02-21 16:21:14","TRT01EDTM":"2022-02-21 04:21:14","TRT02SDTM":"2022-02-21 04:21:14","TRT02EDTM":"2023-02-21 10:21:14","AP01SDTM":"2020-02-21 16:21:14","AP01EDTM":"2022-02-21 04:21:14","AP02SDTM":"2022-02-21 04:21:14","AP02EDTM":"2023-02-21 10:21:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-21","EOSDY":1096,"LSTALVDT":"2023-03-06","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8289,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98687,"AVALU":"g/L","BASE2":3.05606,"BASE":2.85455,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06919,"PCHG2":-2.264,"CHG":0.13232,"PCHG":4.63531,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-24 16:21:14","ADY":489,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-78","SUBJID":"id-78","SITEID":"CHN-1","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.74209,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-21 16:21:14","TRTEDTM":"2023-02-21 10:21:14","TRT01SDTM":"2020-02-21 16:21:14","TRT01EDTM":"2022-02-21 04:21:14","TRT02SDTM":"2022-02-21 04:21:14","TRT02EDTM":"2023-02-21 10:21:14","AP01SDTM":"2020-02-21 16:21:14","AP01EDTM":"2022-02-21 04:21:14","AP02SDTM":"2022-02-21 04:21:14","AP02EDTM":"2023-02-21 10:21:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-21","EOSDY":1096,"LSTALVDT":"2023-03-06","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3660,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78369,"AVALU":"g/L","BASE2":3.05606,"BASE":2.85455,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.27237,"PCHG2":-8.91241,"CHG":-0.07086,"PCHG":-2.48243,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-06 16:21:14","ADY":532,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-78","SUBJID":"id-78","SITEID":"CHN-1","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.74209,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-21 16:21:14","TRTEDTM":"2023-02-21 10:21:14","TRT01SDTM":"2020-02-21 16:21:14","TRT01EDTM":"2022-02-21 04:21:14","TRT02SDTM":"2022-02-21 04:21:14","TRT02EDTM":"2023-02-21 10:21:14","AP01SDTM":"2020-02-21 16:21:14","AP01EDTM":"2022-02-21 04:21:14","AP02SDTM":"2022-02-21 04:21:14","AP02EDTM":"2023-02-21 10:21:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-21","EOSDY":1096,"LSTALVDT":"2023-03-06","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1485,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97371,"AVALU":"g/L","BASE2":3.05606,"BASE":2.85455,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08235,"PCHG2":-2.69451,"CHG":0.11916,"PCHG":4.17441,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-28 16:21:14","ADY":646,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-78","SUBJID":"id-78","SITEID":"CHN-1","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.74209,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-21 16:21:14","TRTEDTM":"2023-02-21 10:21:14","TRT01SDTM":"2020-02-21 16:21:14","TRT01EDTM":"2022-02-21 04:21:14","TRT02SDTM":"2022-02-21 04:21:14","TRT02EDTM":"2023-02-21 10:21:14","AP01SDTM":"2020-02-21 16:21:14","AP01EDTM":"2022-02-21 04:21:14","AP02SDTM":"2022-02-21 04:21:14","AP02EDTM":"2023-02-21 10:21:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-21","EOSDY":1096,"LSTALVDT":"2023-03-06","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3920,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86424,"AVALU":"g/L","BASE2":3.05606,"BASE":2.85455,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19182,"PCHG2":-6.27668,"CHG":0.00969,"PCHG":0.33936,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-10 16:21:14","ADY":689,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-78","SUBJID":"id-78","SITEID":"CHN-1","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.74209,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-21 16:21:14","TRTEDTM":"2023-02-21 10:21:14","TRT01SDTM":"2020-02-21 16:21:14","TRT01EDTM":"2022-02-21 04:21:14","TRT02SDTM":"2022-02-21 04:21:14","TRT02EDTM":"2023-02-21 10:21:14","AP01SDTM":"2020-02-21 16:21:14","AP01EDTM":"2022-02-21 04:21:14","AP02SDTM":"2022-02-21 04:21:14","AP02EDTM":"2023-02-21 10:21:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-21","EOSDY":1096,"LSTALVDT":"2023-03-06","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":806,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85801,"AVALU":"g/L","BASE2":3.05606,"BASE":2.85455,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19805,"PCHG2":-6.48072,"CHG":0.00345,"PCHG":0.12092,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-13 16:21:14","ADY":965,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-86","SUBJID":"id-86","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.36363,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-11","TRTSDTM":"2020-05-15 00:18:43","TRTEDTM":"2023-05-15 18:18:43","TRT01SDTM":"2020-05-15 00:18:43","TRT01EDTM":"2022-05-15 12:18:43","TRT02SDTM":"2022-05-15 12:18:43","TRT02EDTM":"2023-05-15 18:18:43","AP01SDTM":"2020-05-15 00:18:43","AP01EDTM":"2022-05-15 12:18:43","AP02SDTM":"2022-05-15 12:18:43","AP02EDTM":"2023-05-15 18:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-15","EOSDY":1096,"LSTALVDT":"2023-05-31","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":817,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.30345,"AVALU":"U/L","BASE2":17.30345,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-19 00:18:43","ADY":280,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-86","SUBJID":"id-86","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.36363,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-11","TRTSDTM":"2020-05-15 00:18:43","TRTEDTM":"2023-05-15 18:18:43","TRT01SDTM":"2020-05-15 00:18:43","TRT01EDTM":"2022-05-15 12:18:43","TRT02SDTM":"2022-05-15 12:18:43","TRT02EDTM":"2023-05-15 18:18:43","AP01SDTM":"2020-05-15 00:18:43","AP01EDTM":"2022-05-15 12:18:43","AP02SDTM":"2022-05-15 12:18:43","AP02EDTM":"2023-05-15 18:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-15","EOSDY":1096,"LSTALVDT":"2023-05-31","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7685,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.54477,"AVALU":"U/L","BASE2":17.30345,"BASE":18.54477,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.24132,"PCHG2":7.17381,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-31 00:18:43","ADY":534,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-86","SUBJID":"id-86","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.36363,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-11","TRTSDTM":"2020-05-15 00:18:43","TRTEDTM":"2023-05-15 18:18:43","TRT01SDTM":"2020-05-15 00:18:43","TRT01EDTM":"2022-05-15 12:18:43","TRT02SDTM":"2022-05-15 12:18:43","TRT02EDTM":"2023-05-15 18:18:43","AP01SDTM":"2020-05-15 00:18:43","AP01EDTM":"2022-05-15 12:18:43","AP02SDTM":"2022-05-15 12:18:43","AP02EDTM":"2023-05-15 18:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-15","EOSDY":1096,"LSTALVDT":"2023-05-31","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1356,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.71168,"AVALU":"U/L","BASE2":17.30345,"BASE":18.54477,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.40823,"PCHG2":8.13844,"CHG":0.16691,"PCHG":0.90006,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-27 00:18:43","ADY":561,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-86","SUBJID":"id-86","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.36363,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-11","TRTSDTM":"2020-05-15 00:18:43","TRTEDTM":"2023-05-15 18:18:43","TRT01SDTM":"2020-05-15 00:18:43","TRT01EDTM":"2022-05-15 12:18:43","TRT02SDTM":"2022-05-15 12:18:43","TRT02EDTM":"2023-05-15 18:18:43","AP01SDTM":"2020-05-15 00:18:43","AP01EDTM":"2022-05-15 12:18:43","AP02SDTM":"2022-05-15 12:18:43","AP02EDTM":"2023-05-15 18:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-15","EOSDY":1096,"LSTALVDT":"2023-05-31","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7158,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.09557,"AVALU":"U/L","BASE2":17.30345,"BASE":18.54477,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.79212,"PCHG2":68.14895,"CHG":10.5508,"PCHG":56.8937,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-11 00:18:43","ADY":665,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-86","SUBJID":"id-86","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.36363,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-11","TRTSDTM":"2020-05-15 00:18:43","TRTEDTM":"2023-05-15 18:18:43","TRT01SDTM":"2020-05-15 00:18:43","TRT01EDTM":"2022-05-15 12:18:43","TRT02SDTM":"2022-05-15 12:18:43","TRT02EDTM":"2023-05-15 18:18:43","AP01SDTM":"2020-05-15 00:18:43","AP01EDTM":"2022-05-15 12:18:43","AP02SDTM":"2022-05-15 12:18:43","AP02EDTM":"2023-05-15 18:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-15","EOSDY":1096,"LSTALVDT":"2023-05-31","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":946,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.34815,"AVALU":"U/L","BASE2":17.30345,"BASE":18.54477,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.9553,"PCHG2":-69.09201,"CHG":-13.19662,"PCHG":-71.16087,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-09-17 00:18:43","ADY":855,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-86","SUBJID":"id-86","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.36363,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-11","TRTSDTM":"2020-05-15 00:18:43","TRTEDTM":"2023-05-15 18:18:43","TRT01SDTM":"2020-05-15 00:18:43","TRT01EDTM":"2022-05-15 12:18:43","TRT02SDTM":"2022-05-15 12:18:43","TRT02EDTM":"2023-05-15 18:18:43","AP01SDTM":"2020-05-15 00:18:43","AP01EDTM":"2022-05-15 12:18:43","AP02SDTM":"2022-05-15 12:18:43","AP02EDTM":"2023-05-15 18:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-15","EOSDY":1096,"LSTALVDT":"2023-05-31","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3619,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.72706,"AVALU":"U/L","BASE2":17.30345,"BASE":18.54477,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.4236,"PCHG2":89.136,"CHG":14.18229,"PCHG":76.47595,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-17 00:18:43","ADY":885,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-86","SUBJID":"id-86","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.36363,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-11","TRTSDTM":"2020-05-15 00:18:43","TRTEDTM":"2023-05-15 18:18:43","TRT01SDTM":"2020-05-15 00:18:43","TRT01EDTM":"2022-05-15 12:18:43","TRT02SDTM":"2022-05-15 12:18:43","TRT02EDTM":"2023-05-15 18:18:43","AP01SDTM":"2020-05-15 00:18:43","AP01EDTM":"2022-05-15 12:18:43","AP02SDTM":"2022-05-15 12:18:43","AP02EDTM":"2023-05-15 18:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-15","EOSDY":1096,"LSTALVDT":"2023-05-31","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1295,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.27814,"AVALU":"U/L","BASE2":17.30345,"BASE":18.54477,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.02531,"PCHG2":-11.70467,"CHG":-3.26663,"PCHG":-17.61483,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-29 00:18:43","ADY":958,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-86","SUBJID":"id-86","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.36363,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-11","TRTSDTM":"2020-05-15 00:18:43","TRTEDTM":"2023-05-15 18:18:43","TRT01SDTM":"2020-05-15 00:18:43","TRT01EDTM":"2022-05-15 12:18:43","TRT02SDTM":"2022-05-15 12:18:43","TRT02EDTM":"2023-05-15 18:18:43","AP01SDTM":"2020-05-15 00:18:43","AP01EDTM":"2022-05-15 12:18:43","AP02SDTM":"2022-05-15 12:18:43","AP02EDTM":"2023-05-15 18:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-15","EOSDY":1096,"LSTALVDT":"2023-05-31","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2195,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.28462,"AVALU":"mg/L","BASE2":9.28462,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-19 00:18:43","ADY":280,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-86","SUBJID":"id-86","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.36363,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-11","TRTSDTM":"2020-05-15 00:18:43","TRTEDTM":"2023-05-15 18:18:43","TRT01SDTM":"2020-05-15 00:18:43","TRT01EDTM":"2022-05-15 12:18:43","TRT02SDTM":"2022-05-15 12:18:43","TRT02EDTM":"2023-05-15 18:18:43","AP01SDTM":"2020-05-15 00:18:43","AP01EDTM":"2022-05-15 12:18:43","AP02SDTM":"2022-05-15 12:18:43","AP02EDTM":"2023-05-15 18:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-15","EOSDY":1096,"LSTALVDT":"2023-05-31","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7505,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.56431,"AVALU":"mg/L","BASE2":9.28462,"BASE":8.56431,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.7203,"PCHG2":-7.75802,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-31 00:18:43","ADY":534,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-86","SUBJID":"id-86","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.36363,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-11","TRTSDTM":"2020-05-15 00:18:43","TRTEDTM":"2023-05-15 18:18:43","TRT01SDTM":"2020-05-15 00:18:43","TRT01EDTM":"2022-05-15 12:18:43","TRT02SDTM":"2022-05-15 12:18:43","TRT02EDTM":"2023-05-15 18:18:43","AP01SDTM":"2020-05-15 00:18:43","AP01EDTM":"2022-05-15 12:18:43","AP02SDTM":"2022-05-15 12:18:43","AP02EDTM":"2023-05-15 18:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-15","EOSDY":1096,"LSTALVDT":"2023-05-31","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7316,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.31946,"AVALU":"mg/L","BASE2":9.28462,"BASE":8.56431,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.96516,"PCHG2":-21.16575,"CHG":-1.24486,"PCHG":-14.53538,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-11-27 00:18:43","ADY":561,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-86","SUBJID":"id-86","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.36363,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-11","TRTSDTM":"2020-05-15 00:18:43","TRTEDTM":"2023-05-15 18:18:43","TRT01SDTM":"2020-05-15 00:18:43","TRT01EDTM":"2022-05-15 12:18:43","TRT02SDTM":"2022-05-15 12:18:43","TRT02EDTM":"2023-05-15 18:18:43","AP01SDTM":"2020-05-15 00:18:43","AP01EDTM":"2022-05-15 12:18:43","AP02SDTM":"2022-05-15 12:18:43","AP02EDTM":"2023-05-15 18:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-15","EOSDY":1096,"LSTALVDT":"2023-05-31","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1647,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.97175,"AVALU":"mg/L","BASE2":9.28462,"BASE":8.56431,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.31286,"PCHG2":-14.14021,"CHG":-0.59256,"PCHG":-6.91896,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-03-11 00:18:43","ADY":665,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-86","SUBJID":"id-86","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.36363,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-11","TRTSDTM":"2020-05-15 00:18:43","TRTEDTM":"2023-05-15 18:18:43","TRT01SDTM":"2020-05-15 00:18:43","TRT01EDTM":"2022-05-15 12:18:43","TRT02SDTM":"2022-05-15 12:18:43","TRT02EDTM":"2023-05-15 18:18:43","AP01SDTM":"2020-05-15 00:18:43","AP01EDTM":"2022-05-15 12:18:43","AP02SDTM":"2022-05-15 12:18:43","AP02EDTM":"2023-05-15 18:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-15","EOSDY":1096,"LSTALVDT":"2023-05-31","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7574,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.28299,"AVALU":"mg/L","BASE2":9.28462,"BASE":8.56431,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00162,"PCHG2":-0.01748,"CHG":0.71868,"PCHG":8.39156,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-17 00:18:43","ADY":855,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-86","SUBJID":"id-86","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.36363,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-11","TRTSDTM":"2020-05-15 00:18:43","TRTEDTM":"2023-05-15 18:18:43","TRT01SDTM":"2020-05-15 00:18:43","TRT01EDTM":"2022-05-15 12:18:43","TRT02SDTM":"2022-05-15 12:18:43","TRT02EDTM":"2023-05-15 18:18:43","AP01SDTM":"2020-05-15 00:18:43","AP01EDTM":"2022-05-15 12:18:43","AP02SDTM":"2022-05-15 12:18:43","AP02EDTM":"2023-05-15 18:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-15","EOSDY":1096,"LSTALVDT":"2023-05-31","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4275,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.27165,"AVALU":"mg/L","BASE2":9.28462,"BASE":8.56431,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.01297,"PCHG2":-10.91015,"CHG":-0.29266,"PCHG":-3.41724,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-17 00:18:43","ADY":885,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-86","SUBJID":"id-86","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.36363,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-11","TRTSDTM":"2020-05-15 00:18:43","TRTEDTM":"2023-05-15 18:18:43","TRT01SDTM":"2020-05-15 00:18:43","TRT01EDTM":"2022-05-15 12:18:43","TRT02SDTM":"2022-05-15 12:18:43","TRT02EDTM":"2023-05-15 18:18:43","AP01SDTM":"2020-05-15 00:18:43","AP01EDTM":"2022-05-15 12:18:43","AP02SDTM":"2022-05-15 12:18:43","AP02EDTM":"2023-05-15 18:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-15","EOSDY":1096,"LSTALVDT":"2023-05-31","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4620,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.44391,"AVALU":"mg/L","BASE2":9.28462,"BASE":8.56431,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.8407,"PCHG2":-9.05481,"CHG":-0.1204,"PCHG":-1.40586,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-29 00:18:43","ADY":958,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-86","SUBJID":"id-86","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.36363,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-11","TRTSDTM":"2020-05-15 00:18:43","TRTEDTM":"2023-05-15 18:18:43","TRT01SDTM":"2020-05-15 00:18:43","TRT01EDTM":"2022-05-15 12:18:43","TRT02SDTM":"2022-05-15 12:18:43","TRT02EDTM":"2023-05-15 18:18:43","AP01SDTM":"2020-05-15 00:18:43","AP01EDTM":"2022-05-15 12:18:43","AP02SDTM":"2022-05-15 12:18:43","AP02EDTM":"2023-05-15 18:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-15","EOSDY":1096,"LSTALVDT":"2023-05-31","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7782,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01501,"AVALU":"g/L","BASE2":3.01501,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"4","BTOXGR":"0","ADTM":"2021-02-19 00:18:43","ADY":280,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-86","SUBJID":"id-86","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.36363,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-11","TRTSDTM":"2020-05-15 00:18:43","TRTEDTM":"2023-05-15 18:18:43","TRT01SDTM":"2020-05-15 00:18:43","TRT01EDTM":"2022-05-15 12:18:43","TRT02SDTM":"2022-05-15 12:18:43","TRT02EDTM":"2023-05-15 18:18:43","AP01SDTM":"2020-05-15 00:18:43","AP01EDTM":"2022-05-15 12:18:43","AP02SDTM":"2022-05-15 12:18:43","AP02EDTM":"2023-05-15 18:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-15","EOSDY":1096,"LSTALVDT":"2023-05-31","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2441,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86606,"AVALU":"g/L","BASE2":3.01501,"BASE":2.86606,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.14896,"PCHG2":-4.94053,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-31 00:18:43","ADY":534,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-86","SUBJID":"id-86","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.36363,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-11","TRTSDTM":"2020-05-15 00:18:43","TRTEDTM":"2023-05-15 18:18:43","TRT01SDTM":"2020-05-15 00:18:43","TRT01EDTM":"2022-05-15 12:18:43","TRT02SDTM":"2022-05-15 12:18:43","TRT02EDTM":"2023-05-15 18:18:43","AP01SDTM":"2020-05-15 00:18:43","AP01EDTM":"2022-05-15 12:18:43","AP02SDTM":"2022-05-15 12:18:43","AP02EDTM":"2023-05-15 18:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-15","EOSDY":1096,"LSTALVDT":"2023-05-31","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7408,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99249,"AVALU":"g/L","BASE2":3.01501,"BASE":2.86606,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02252,"PCHG2":-0.74706,"CHG":0.12643,"PCHG":4.41142,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-27 00:18:43","ADY":561,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-86","SUBJID":"id-86","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.36363,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-11","TRTSDTM":"2020-05-15 00:18:43","TRTEDTM":"2023-05-15 18:18:43","TRT01SDTM":"2020-05-15 00:18:43","TRT01EDTM":"2022-05-15 12:18:43","TRT02SDTM":"2022-05-15 12:18:43","TRT02EDTM":"2023-05-15 18:18:43","AP01SDTM":"2020-05-15 00:18:43","AP01EDTM":"2022-05-15 12:18:43","AP02SDTM":"2022-05-15 12:18:43","AP02EDTM":"2023-05-15 18:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-15","EOSDY":1096,"LSTALVDT":"2023-05-31","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":272,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91287,"AVALU":"g/L","BASE2":3.01501,"BASE":2.86606,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10214,"PCHG2":-3.38769,"CHG":0.04682,"PCHG":1.63354,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-11 00:18:43","ADY":665,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-86","SUBJID":"id-86","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.36363,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-11","TRTSDTM":"2020-05-15 00:18:43","TRTEDTM":"2023-05-15 18:18:43","TRT01SDTM":"2020-05-15 00:18:43","TRT01EDTM":"2022-05-15 12:18:43","TRT02SDTM":"2022-05-15 12:18:43","TRT02EDTM":"2023-05-15 18:18:43","AP01SDTM":"2020-05-15 00:18:43","AP01EDTM":"2022-05-15 12:18:43","AP02SDTM":"2022-05-15 12:18:43","AP02EDTM":"2023-05-15 18:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-15","EOSDY":1096,"LSTALVDT":"2023-05-31","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8203,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81175,"AVALU":"g/L","BASE2":3.01501,"BASE":2.86606,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20326,"PCHG2":-6.74159,"CHG":-0.0543,"PCHG":-1.89467,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-17 00:18:43","ADY":855,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-86","SUBJID":"id-86","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.36363,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-11","TRTSDTM":"2020-05-15 00:18:43","TRTEDTM":"2023-05-15 18:18:43","TRT01SDTM":"2020-05-15 00:18:43","TRT01EDTM":"2022-05-15 12:18:43","TRT02SDTM":"2022-05-15 12:18:43","TRT02EDTM":"2023-05-15 18:18:43","AP01SDTM":"2020-05-15 00:18:43","AP01EDTM":"2022-05-15 12:18:43","AP02SDTM":"2022-05-15 12:18:43","AP02EDTM":"2023-05-15 18:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-15","EOSDY":1096,"LSTALVDT":"2023-05-31","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":972,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81593,"AVALU":"g/L","BASE2":3.01501,"BASE":2.86606,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19908,"PCHG2":-6.60298,"CHG":-0.05012,"PCHG":-1.74885,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-17 00:18:43","ADY":885,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-86","SUBJID":"id-86","SITEID":"CHN-1","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.36363,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-11","TRTSDTM":"2020-05-15 00:18:43","TRTEDTM":"2023-05-15 18:18:43","TRT01SDTM":"2020-05-15 00:18:43","TRT01EDTM":"2022-05-15 12:18:43","TRT02SDTM":"2022-05-15 12:18:43","TRT02EDTM":"2023-05-15 18:18:43","AP01SDTM":"2020-05-15 00:18:43","AP01EDTM":"2022-05-15 12:18:43","AP02SDTM":"2022-05-15 12:18:43","AP02EDTM":"2023-05-15 18:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-15","EOSDY":1096,"LSTALVDT":"2023-05-31","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4429,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86497,"AVALU":"g/L","BASE2":3.01501,"BASE":2.86606,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15004,"PCHG2":-4.97658,"CHG":-0.00109,"PCHG":-0.03793,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-29 00:18:43","ADY":958,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-97","SUBJID":"id-97","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.49296,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-20 08:09:12","TRT01SDTM":"2020-01-20 08:09:12","AP01SDTM":"2020-01-20 08:09:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5453,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.64587,"AVALU":"U/L","BASE2":32.64587,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-02 08:09:12","ADY":103,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-97","SUBJID":"id-97","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.49296,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-20 08:09:12","TRT01SDTM":"2020-01-20 08:09:12","AP01SDTM":"2020-01-20 08:09:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3241,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.69663,"AVALU":"U/L","BASE2":32.64587,"BASE":11.69663,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-20.94924,"PCHG2":-64.17119,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-04 08:09:12","ADY":228,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-97","SUBJID":"id-97","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.49296,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-20 08:09:12","TRT01SDTM":"2020-01-20 08:09:12","AP01SDTM":"2020-01-20 08:09:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5113,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.32168,"AVALU":"U/L","BASE2":32.64587,"BASE":11.69663,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.3242,"PCHG2":-10.1826,"CHG":17.62505,"PCHG":150.68486,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-07 08:09:12","ADY":292,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-97","SUBJID":"id-97","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.49296,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-20 08:09:12","TRT01SDTM":"2020-01-20 08:09:12","AP01SDTM":"2020-01-20 08:09:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5292,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.67233,"AVALU":"U/L","BASE2":32.64587,"BASE":11.69663,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.97355,"PCHG2":-27.48753,"CHG":11.9757,"PCHG":102.38591,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-08 08:09:12","ADY":535,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-97","SUBJID":"id-97","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.49296,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-20 08:09:12","TRT01SDTM":"2020-01-20 08:09:12","AP01SDTM":"2020-01-20 08:09:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4131,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.07234,"AVALU":"U/L","BASE2":32.64587,"BASE":11.69663,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.57353,"PCHG2":-32.38857,"CHG":10.37571,"PCHG":88.70688,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-10 08:09:12","ADY":537,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-97","SUBJID":"id-97","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.49296,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-20 08:09:12","TRT01SDTM":"2020-01-20 08:09:12","AP01SDTM":"2020-01-20 08:09:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5850,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":40.94028,"AVALU":"U/L","BASE2":32.64587,"BASE":11.69663,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.29441,"PCHG2":25.40722,"CHG":29.24365,"PCHG":250.01782,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-30 08:09:12","ADY":557,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-97","SUBJID":"id-97","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.49296,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-20 08:09:12","TRT01SDTM":"2020-01-20 08:09:12","AP01SDTM":"2020-01-20 08:09:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6330,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.59862,"AVALU":"U/L","BASE2":32.64587,"BASE":11.69663,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.04726,"PCHG2":-18.5238,"CHG":14.90199,"PCHG":127.40413,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-05 08:09:12","ADY":716,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-97","SUBJID":"id-97","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.49296,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-20 08:09:12","TRT01SDTM":"2020-01-20 08:09:12","AP01SDTM":"2020-01-20 08:09:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8099,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.29628,"AVALU":"mg/L","BASE2":9.29628,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-05-02 08:09:12","ADY":103,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-97","SUBJID":"id-97","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.49296,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-20 08:09:12","TRT01SDTM":"2020-01-20 08:09:12","AP01SDTM":"2020-01-20 08:09:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5645,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.12589,"AVALU":"mg/L","BASE2":9.29628,"BASE":7.12589,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.17039,"PCHG2":-23.34685,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2020-09-04 08:09:12","ADY":228,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-97","SUBJID":"id-97","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.49296,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-20 08:09:12","TRT01SDTM":"2020-01-20 08:09:12","AP01SDTM":"2020-01-20 08:09:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4452,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.47938,"AVALU":"mg/L","BASE2":9.29628,"BASE":7.12589,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1831,"PCHG2":1.96962,"CHG":2.35349,"PCHG":33.02731,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-11-07 08:09:12","ADY":292,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-97","SUBJID":"id-97","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.49296,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-20 08:09:12","TRT01SDTM":"2020-01-20 08:09:12","AP01SDTM":"2020-01-20 08:09:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3890,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.9031,"AVALU":"mg/L","BASE2":9.29628,"BASE":7.12589,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.60682,"PCHG2":6.52755,"CHG":2.77721,"PCHG":38.97348,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-07-08 08:09:12","ADY":535,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-97","SUBJID":"id-97","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.49296,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-20 08:09:12","TRT01SDTM":"2020-01-20 08:09:12","AP01SDTM":"2020-01-20 08:09:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3032,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.36781,"AVALU":"mg/L","BASE2":9.29628,"BASE":7.12589,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.07153,"PCHG2":22.28345,"CHG":4.24192,"PCHG":59.52828,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"3","BTOXGR":"-1","ADTM":"2021-07-10 08:09:12","ADY":537,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-97","SUBJID":"id-97","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.49296,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-20 08:09:12","TRT01SDTM":"2020-01-20 08:09:12","AP01SDTM":"2020-01-20 08:09:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4823,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.0257,"AVALU":"mg/L","BASE2":9.29628,"BASE":7.12589,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.72942,"PCHG2":7.84641,"CHG":2.89981,"PCHG":40.69403,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"2","BTOXGR":"-1","ADTM":"2021-07-30 08:09:12","ADY":557,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-97","SUBJID":"id-97","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.49296,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-20 08:09:12","TRT01SDTM":"2020-01-20 08:09:12","AP01SDTM":"2020-01-20 08:09:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1545,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.2634,"AVALU":"mg/L","BASE2":9.29628,"BASE":7.12589,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.96712,"PCHG2":10.40333,"CHG":3.13751,"PCHG":44.02973,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"1","BTOXGR":"-1","ADTM":"2022-01-05 08:09:12","ADY":716,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-97","SUBJID":"id-97","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.49296,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-20 08:09:12","TRT01SDTM":"2020-01-20 08:09:12","AP01SDTM":"2020-01-20 08:09:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4787,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91024,"AVALU":"g/L","BASE2":2.91024,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-02 08:09:12","ADY":103,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-97","SUBJID":"id-97","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.49296,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-20 08:09:12","TRT01SDTM":"2020-01-20 08:09:12","AP01SDTM":"2020-01-20 08:09:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6939,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97424,"AVALU":"g/L","BASE2":2.91024,"BASE":2.97424,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.064,"PCHG2":2.19909,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-04 08:09:12","ADY":228,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-97","SUBJID":"id-97","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.49296,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-20 08:09:12","TRT01SDTM":"2020-01-20 08:09:12","AP01SDTM":"2020-01-20 08:09:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5659,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86128,"AVALU":"g/L","BASE2":2.91024,"BASE":2.97424,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04896,"PCHG2":-1.68243,"CHG":-0.11296,"PCHG":-3.798,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-07 08:09:12","ADY":292,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-97","SUBJID":"id-97","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.49296,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-20 08:09:12","TRT01SDTM":"2020-01-20 08:09:12","AP01SDTM":"2020-01-20 08:09:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4766,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96439,"AVALU":"g/L","BASE2":2.91024,"BASE":2.97424,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05416,"PCHG2":1.86088,"CHG":-0.00984,"PCHG":-0.33094,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-08 08:09:12","ADY":535,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-97","SUBJID":"id-97","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.49296,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-20 08:09:12","TRT01SDTM":"2020-01-20 08:09:12","AP01SDTM":"2020-01-20 08:09:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5729,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98785,"AVALU":"g/L","BASE2":2.91024,"BASE":2.97424,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07762,"PCHG2":2.667,"CHG":0.01362,"PCHG":0.45784,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-10 08:09:12","ADY":537,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-97","SUBJID":"id-97","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.49296,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-20 08:09:12","TRT01SDTM":"2020-01-20 08:09:12","AP01SDTM":"2020-01-20 08:09:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8068,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85156,"AVALU":"g/L","BASE2":2.91024,"BASE":2.97424,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05868,"PCHG2":-2.01619,"CHG":-0.12267,"PCHG":-4.12458,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-30 08:09:12","ADY":557,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-1-id-97","SUBJID":"id-97","SITEID":"CHN-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-1","INVNAM":"Dr. CHN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.49296,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-20 08:09:12","TRT01SDTM":"2020-01-20 08:09:12","AP01SDTM":"2020-01-20 08:09:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":739,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99772,"AVALU":"g/L","BASE2":2.91024,"BASE":2.97424,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08748,"PCHG2":3.00599,"CHG":0.02348,"PCHG":0.78953,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-05 08:09:12","ADY":716,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-10-id-380","SUBJID":"id-380","SITEID":"CHN-10","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-10","INVNAM":"Dr. CHN-10 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.37548,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-09 18:45:03","TRTEDTM":"2022-02-12 15:34:26","TRT01SDTM":"2020-05-09 18:45:03","TRT01EDTM":"2021-02-12 09:34:26","TRT02SDTM":"2021-02-12 09:34:26","TRT02EDTM":"2022-02-12 15:34:26","AP01SDTM":"2020-05-09 18:45:03","AP01EDTM":"2021-02-12 09:34:26","AP02SDTM":"2021-02-12 09:34:26","AP02EDTM":"2022-02-12 15:34:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":644,"DCSREAS":"DEATH","DTHDT":"2022-02-19","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-19","DTHADY":650,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4151,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.36222,"AVALU":"U/L","BASE2":19.36222,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-21 18:45:03","ADY":73,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-10-id-380","SUBJID":"id-380","SITEID":"CHN-10","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-10","INVNAM":"Dr. CHN-10 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.37548,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-09 18:45:03","TRTEDTM":"2022-02-12 15:34:26","TRT01SDTM":"2020-05-09 18:45:03","TRT01EDTM":"2021-02-12 09:34:26","TRT02SDTM":"2021-02-12 09:34:26","TRT02EDTM":"2022-02-12 15:34:26","AP01SDTM":"2020-05-09 18:45:03","AP01EDTM":"2021-02-12 09:34:26","AP02SDTM":"2021-02-12 09:34:26","AP02EDTM":"2022-02-12 15:34:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":644,"DCSREAS":"DEATH","DTHDT":"2022-02-19","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-19","DTHADY":650,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7696,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.41455,"AVALU":"U/L","BASE2":19.36222,"BASE":11.41455,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-7.94767,"PCHG2":-41.04731,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-17 18:45:03","ADY":161,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-10-id-380","SUBJID":"id-380","SITEID":"CHN-10","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-10","INVNAM":"Dr. CHN-10 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.37548,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-09 18:45:03","TRTEDTM":"2022-02-12 15:34:26","TRT01SDTM":"2020-05-09 18:45:03","TRT01EDTM":"2021-02-12 09:34:26","TRT02SDTM":"2021-02-12 09:34:26","TRT02EDTM":"2022-02-12 15:34:26","AP01SDTM":"2020-05-09 18:45:03","AP01EDTM":"2021-02-12 09:34:26","AP02SDTM":"2021-02-12 09:34:26","AP02EDTM":"2022-02-12 15:34:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":644,"DCSREAS":"DEATH","DTHDT":"2022-02-19","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-19","DTHADY":650,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4424,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":37.76288,"AVALU":"U/L","BASE2":19.36222,"BASE":11.41455,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.40066,"PCHG2":95.03384,"CHG":26.34833,"PCHG":230.8311,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-27 18:45:03","ADY":383,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-10-id-380","SUBJID":"id-380","SITEID":"CHN-10","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-10","INVNAM":"Dr. CHN-10 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.37548,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-09 18:45:03","TRTEDTM":"2022-02-12 15:34:26","TRT01SDTM":"2020-05-09 18:45:03","TRT01EDTM":"2021-02-12 09:34:26","TRT02SDTM":"2021-02-12 09:34:26","TRT02EDTM":"2022-02-12 15:34:26","AP01SDTM":"2020-05-09 18:45:03","AP01EDTM":"2021-02-12 09:34:26","AP02SDTM":"2021-02-12 09:34:26","AP02EDTM":"2022-02-12 15:34:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":644,"DCSREAS":"DEATH","DTHDT":"2022-02-19","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-19","DTHADY":650,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1774,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.91079,"AVALU":"U/L","BASE2":19.36222,"BASE":11.41455,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.54857,"PCHG2":18.32731,"CHG":11.49624,"PCHG":100.7157,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-14 18:45:03","ADY":493,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-10-id-380","SUBJID":"id-380","SITEID":"CHN-10","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-10","INVNAM":"Dr. CHN-10 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.37548,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-09 18:45:03","TRTEDTM":"2022-02-12 15:34:26","TRT01SDTM":"2020-05-09 18:45:03","TRT01EDTM":"2021-02-12 09:34:26","TRT02SDTM":"2021-02-12 09:34:26","TRT02EDTM":"2022-02-12 15:34:26","AP01SDTM":"2020-05-09 18:45:03","AP01EDTM":"2021-02-12 09:34:26","AP02SDTM":"2021-02-12 09:34:26","AP02EDTM":"2022-02-12 15:34:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":644,"DCSREAS":"DEATH","DTHDT":"2022-02-19","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-19","DTHADY":650,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6838,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.75828,"AVALU":"U/L","BASE2":19.36222,"BASE":11.41455,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.60394,"PCHG2":-39.27203,"CHG":0.34373,"PCHG":3.01136,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-27 18:45:03","ADY":506,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-10-id-380","SUBJID":"id-380","SITEID":"CHN-10","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-10","INVNAM":"Dr. CHN-10 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.37548,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-09 18:45:03","TRTEDTM":"2022-02-12 15:34:26","TRT01SDTM":"2020-05-09 18:45:03","TRT01EDTM":"2021-02-12 09:34:26","TRT02SDTM":"2021-02-12 09:34:26","TRT02EDTM":"2022-02-12 15:34:26","AP01SDTM":"2020-05-09 18:45:03","AP01EDTM":"2021-02-12 09:34:26","AP02SDTM":"2021-02-12 09:34:26","AP02EDTM":"2022-02-12 15:34:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":644,"DCSREAS":"DEATH","DTHDT":"2022-02-19","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-19","DTHADY":650,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7534,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.05109,"AVALU":"U/L","BASE2":19.36222,"BASE":11.41455,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.31113,"PCHG2":-22.26569,"CHG":3.63654,"PCHG":31.85879,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-05 18:45:03","ADY":514,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-10-id-380","SUBJID":"id-380","SITEID":"CHN-10","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-10","INVNAM":"Dr. CHN-10 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.37548,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-09 18:45:03","TRTEDTM":"2022-02-12 15:34:26","TRT01SDTM":"2020-05-09 18:45:03","TRT01EDTM":"2021-02-12 09:34:26","TRT02SDTM":"2021-02-12 09:34:26","TRT02EDTM":"2022-02-12 15:34:26","AP01SDTM":"2020-05-09 18:45:03","AP01EDTM":"2021-02-12 09:34:26","AP02SDTM":"2021-02-12 09:34:26","AP02EDTM":"2022-02-12 15:34:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":644,"DCSREAS":"DEATH","DTHDT":"2022-02-19","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-19","DTHADY":650,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1057,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.34081,"AVALU":"U/L","BASE2":19.36222,"BASE":11.41455,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.02141,"PCHG2":-5.27525,"CHG":6.92626,"PCHG":60.67926,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-15 18:45:03","ADY":524,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-10-id-380","SUBJID":"id-380","SITEID":"CHN-10","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-10","INVNAM":"Dr. CHN-10 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.37548,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-09 18:45:03","TRTEDTM":"2022-02-12 15:34:26","TRT01SDTM":"2020-05-09 18:45:03","TRT01EDTM":"2021-02-12 09:34:26","TRT02SDTM":"2021-02-12 09:34:26","TRT02EDTM":"2022-02-12 15:34:26","AP01SDTM":"2020-05-09 18:45:03","AP01EDTM":"2021-02-12 09:34:26","AP02SDTM":"2021-02-12 09:34:26","AP02EDTM":"2022-02-12 15:34:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":644,"DCSREAS":"DEATH","DTHDT":"2022-02-19","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-19","DTHADY":650,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1427,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.58639,"AVALU":"mg/L","BASE2":8.58639,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-21 18:45:03","ADY":73,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-10-id-380","SUBJID":"id-380","SITEID":"CHN-10","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-10","INVNAM":"Dr. CHN-10 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.37548,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-09 18:45:03","TRTEDTM":"2022-02-12 15:34:26","TRT01SDTM":"2020-05-09 18:45:03","TRT01EDTM":"2021-02-12 09:34:26","TRT02SDTM":"2021-02-12 09:34:26","TRT02EDTM":"2022-02-12 15:34:26","AP01SDTM":"2020-05-09 18:45:03","AP01EDTM":"2021-02-12 09:34:26","AP02SDTM":"2021-02-12 09:34:26","AP02EDTM":"2022-02-12 15:34:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":644,"DCSREAS":"DEATH","DTHDT":"2022-02-19","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-19","DTHADY":650,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2084,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.49337,"AVALU":"mg/L","BASE2":8.58639,"BASE":9.49337,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.90698,"PCHG2":10.56294,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-17 18:45:03","ADY":161,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-10-id-380","SUBJID":"id-380","SITEID":"CHN-10","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-10","INVNAM":"Dr. CHN-10 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.37548,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-09 18:45:03","TRTEDTM":"2022-02-12 15:34:26","TRT01SDTM":"2020-05-09 18:45:03","TRT01EDTM":"2021-02-12 09:34:26","TRT02SDTM":"2021-02-12 09:34:26","TRT02EDTM":"2022-02-12 15:34:26","AP01SDTM":"2020-05-09 18:45:03","AP01EDTM":"2021-02-12 09:34:26","AP02SDTM":"2021-02-12 09:34:26","AP02EDTM":"2022-02-12 15:34:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":644,"DCSREAS":"DEATH","DTHDT":"2022-02-19","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-19","DTHADY":650,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1727,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.43098,"AVALU":"mg/L","BASE2":8.58639,"BASE":9.49337,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.84459,"PCHG2":9.83636,"CHG":-0.06239,"PCHG":-0.65717,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-27 18:45:03","ADY":383,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-10-id-380","SUBJID":"id-380","SITEID":"CHN-10","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-10","INVNAM":"Dr. CHN-10 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.37548,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-09 18:45:03","TRTEDTM":"2022-02-12 15:34:26","TRT01SDTM":"2020-05-09 18:45:03","TRT01EDTM":"2021-02-12 09:34:26","TRT02SDTM":"2021-02-12 09:34:26","TRT02EDTM":"2022-02-12 15:34:26","AP01SDTM":"2020-05-09 18:45:03","AP01EDTM":"2021-02-12 09:34:26","AP02SDTM":"2021-02-12 09:34:26","AP02EDTM":"2022-02-12 15:34:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":644,"DCSREAS":"DEATH","DTHDT":"2022-02-19","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-19","DTHADY":650,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6632,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.13115,"AVALU":"mg/L","BASE2":8.58639,"BASE":9.49337,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.45524,"PCHG2":-16.94823,"CHG":-2.36222,"PCHG":-24.88281,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-09-14 18:45:03","ADY":493,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-10-id-380","SUBJID":"id-380","SITEID":"CHN-10","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-10","INVNAM":"Dr. CHN-10 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.37548,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-09 18:45:03","TRTEDTM":"2022-02-12 15:34:26","TRT01SDTM":"2020-05-09 18:45:03","TRT01EDTM":"2021-02-12 09:34:26","TRT02SDTM":"2021-02-12 09:34:26","TRT02EDTM":"2022-02-12 15:34:26","AP01SDTM":"2020-05-09 18:45:03","AP01EDTM":"2021-02-12 09:34:26","AP02SDTM":"2021-02-12 09:34:26","AP02EDTM":"2022-02-12 15:34:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":644,"DCSREAS":"DEATH","DTHDT":"2022-02-19","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-19","DTHADY":650,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5218,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.68741,"AVALU":"mg/L","BASE2":8.58639,"BASE":9.49337,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10102,"PCHG2":1.17648,"CHG":-0.80596,"PCHG":-8.4897,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-27 18:45:03","ADY":506,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-10-id-380","SUBJID":"id-380","SITEID":"CHN-10","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-10","INVNAM":"Dr. CHN-10 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.37548,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-09 18:45:03","TRTEDTM":"2022-02-12 15:34:26","TRT01SDTM":"2020-05-09 18:45:03","TRT01EDTM":"2021-02-12 09:34:26","TRT02SDTM":"2021-02-12 09:34:26","TRT02EDTM":"2022-02-12 15:34:26","AP01SDTM":"2020-05-09 18:45:03","AP01EDTM":"2021-02-12 09:34:26","AP02SDTM":"2021-02-12 09:34:26","AP02EDTM":"2022-02-12 15:34:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":644,"DCSREAS":"DEATH","DTHDT":"2022-02-19","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-19","DTHADY":650,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8371,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.65061,"AVALU":"mg/L","BASE2":8.58639,"BASE":9.49337,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.06422,"PCHG2":12.39425,"CHG":0.15724,"PCHG":1.65635,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-05 18:45:03","ADY":514,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-10-id-380","SUBJID":"id-380","SITEID":"CHN-10","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-10","INVNAM":"Dr. CHN-10 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.37548,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-09 18:45:03","TRTEDTM":"2022-02-12 15:34:26","TRT01SDTM":"2020-05-09 18:45:03","TRT01EDTM":"2021-02-12 09:34:26","TRT02SDTM":"2021-02-12 09:34:26","TRT02EDTM":"2022-02-12 15:34:26","AP01SDTM":"2020-05-09 18:45:03","AP01EDTM":"2021-02-12 09:34:26","AP02SDTM":"2021-02-12 09:34:26","AP02EDTM":"2022-02-12 15:34:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":644,"DCSREAS":"DEATH","DTHDT":"2022-02-19","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-19","DTHADY":650,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7225,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.76556,"AVALU":"mg/L","BASE2":8.58639,"BASE":9.49337,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.17917,"PCHG2":25.37932,"CHG":1.27219,"PCHG":13.40085,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-10-15 18:45:03","ADY":524,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-10-id-380","SUBJID":"id-380","SITEID":"CHN-10","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-10","INVNAM":"Dr. CHN-10 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.37548,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-09 18:45:03","TRTEDTM":"2022-02-12 15:34:26","TRT01SDTM":"2020-05-09 18:45:03","TRT01EDTM":"2021-02-12 09:34:26","TRT02SDTM":"2021-02-12 09:34:26","TRT02EDTM":"2022-02-12 15:34:26","AP01SDTM":"2020-05-09 18:45:03","AP01EDTM":"2021-02-12 09:34:26","AP02SDTM":"2021-02-12 09:34:26","AP02EDTM":"2022-02-12 15:34:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":644,"DCSREAS":"DEATH","DTHDT":"2022-02-19","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-19","DTHADY":650,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3649,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81744,"AVALU":"g/L","BASE2":2.81744,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-21 18:45:03","ADY":73,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-10-id-380","SUBJID":"id-380","SITEID":"CHN-10","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-10","INVNAM":"Dr. CHN-10 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.37548,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-09 18:45:03","TRTEDTM":"2022-02-12 15:34:26","TRT01SDTM":"2020-05-09 18:45:03","TRT01EDTM":"2021-02-12 09:34:26","TRT02SDTM":"2021-02-12 09:34:26","TRT02EDTM":"2022-02-12 15:34:26","AP01SDTM":"2020-05-09 18:45:03","AP01EDTM":"2021-02-12 09:34:26","AP02SDTM":"2021-02-12 09:34:26","AP02EDTM":"2022-02-12 15:34:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":644,"DCSREAS":"DEATH","DTHDT":"2022-02-19","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-19","DTHADY":650,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6927,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89425,"AVALU":"g/L","BASE2":2.81744,"BASE":2.89425,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.07681,"PCHG2":2.72617,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-17 18:45:03","ADY":161,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-10-id-380","SUBJID":"id-380","SITEID":"CHN-10","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-10","INVNAM":"Dr. CHN-10 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.37548,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-09 18:45:03","TRTEDTM":"2022-02-12 15:34:26","TRT01SDTM":"2020-05-09 18:45:03","TRT01EDTM":"2021-02-12 09:34:26","TRT02SDTM":"2021-02-12 09:34:26","TRT02EDTM":"2022-02-12 15:34:26","AP01SDTM":"2020-05-09 18:45:03","AP01EDTM":"2021-02-12 09:34:26","AP02SDTM":"2021-02-12 09:34:26","AP02EDTM":"2022-02-12 15:34:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":644,"DCSREAS":"DEATH","DTHDT":"2022-02-19","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-19","DTHADY":650,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3440,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81109,"AVALU":"g/L","BASE2":2.81744,"BASE":2.89425,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00636,"PCHG2":-0.2256,"CHG":-0.08316,"PCHG":-2.87344,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-27 18:45:03","ADY":383,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-10-id-380","SUBJID":"id-380","SITEID":"CHN-10","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-10","INVNAM":"Dr. CHN-10 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.37548,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-09 18:45:03","TRTEDTM":"2022-02-12 15:34:26","TRT01SDTM":"2020-05-09 18:45:03","TRT01EDTM":"2021-02-12 09:34:26","TRT02SDTM":"2021-02-12 09:34:26","TRT02EDTM":"2022-02-12 15:34:26","AP01SDTM":"2020-05-09 18:45:03","AP01EDTM":"2021-02-12 09:34:26","AP02SDTM":"2021-02-12 09:34:26","AP02EDTM":"2022-02-12 15:34:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":644,"DCSREAS":"DEATH","DTHDT":"2022-02-19","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-19","DTHADY":650,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3279,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81887,"AVALU":"g/L","BASE2":2.81744,"BASE":2.89425,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00142,"PCHG2":0.05046,"CHG":-0.07539,"PCHG":-2.60471,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-14 18:45:03","ADY":493,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-10-id-380","SUBJID":"id-380","SITEID":"CHN-10","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-10","INVNAM":"Dr. CHN-10 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.37548,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-09 18:45:03","TRTEDTM":"2022-02-12 15:34:26","TRT01SDTM":"2020-05-09 18:45:03","TRT01EDTM":"2021-02-12 09:34:26","TRT02SDTM":"2021-02-12 09:34:26","TRT02EDTM":"2022-02-12 15:34:26","AP01SDTM":"2020-05-09 18:45:03","AP01EDTM":"2021-02-12 09:34:26","AP02SDTM":"2021-02-12 09:34:26","AP02EDTM":"2022-02-12 15:34:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":644,"DCSREAS":"DEATH","DTHDT":"2022-02-19","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-19","DTHADY":650,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3480,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91836,"AVALU":"g/L","BASE2":2.81744,"BASE":2.89425,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10091,"PCHG2":3.58174,"CHG":0.0241,"PCHG":0.83286,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-27 18:45:03","ADY":506,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-10-id-380","SUBJID":"id-380","SITEID":"CHN-10","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-10","INVNAM":"Dr. CHN-10 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.37548,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-09 18:45:03","TRTEDTM":"2022-02-12 15:34:26","TRT01SDTM":"2020-05-09 18:45:03","TRT01EDTM":"2021-02-12 09:34:26","TRT02SDTM":"2021-02-12 09:34:26","TRT02EDTM":"2022-02-12 15:34:26","AP01SDTM":"2020-05-09 18:45:03","AP01EDTM":"2021-02-12 09:34:26","AP02SDTM":"2021-02-12 09:34:26","AP02EDTM":"2022-02-12 15:34:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":644,"DCSREAS":"DEATH","DTHDT":"2022-02-19","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-19","DTHADY":650,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1071,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00483,"AVALU":"g/L","BASE2":2.81744,"BASE":2.89425,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18738,"PCHG2":6.65084,"CHG":0.11058,"PCHG":3.82051,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-10-05 18:45:03","ADY":514,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-10-id-380","SUBJID":"id-380","SITEID":"CHN-10","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-10","INVNAM":"Dr. CHN-10 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.37548,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-09 18:45:03","TRTEDTM":"2022-02-12 15:34:26","TRT01SDTM":"2020-05-09 18:45:03","TRT01EDTM":"2021-02-12 09:34:26","TRT02SDTM":"2021-02-12 09:34:26","TRT02EDTM":"2022-02-12 15:34:26","AP01SDTM":"2020-05-09 18:45:03","AP01EDTM":"2021-02-12 09:34:26","AP02SDTM":"2021-02-12 09:34:26","AP02EDTM":"2022-02-12 15:34:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":644,"DCSREAS":"DEATH","DTHDT":"2022-02-19","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-19","DTHADY":650,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2633,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93524,"AVALU":"g/L","BASE2":2.81744,"BASE":2.89425,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11779,"PCHG2":4.18081,"CHG":0.04098,"PCHG":1.41603,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-15 18:45:03","ADY":524,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-113","SUBJID":"id-113","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.86591,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-06","TRTSDTM":"2021-01-10 15:51:53","TRTEDTM":"2024-01-11 09:51:53","TRT01SDTM":"2021-01-10 15:51:53","TRT01EDTM":"2023-01-11 03:51:53","TRT02SDTM":"2023-01-11 03:51:53","TRT02EDTM":"2024-01-11 09:51:53","AP01SDTM":"2021-01-10 15:51:53","AP01EDTM":"2023-01-11 03:51:53","AP02SDTM":"2023-01-11 03:51:53","AP02EDTM":"2024-01-11 09:51:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-11","EOSDY":1096,"LSTALVDT":"2024-02-03","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3337,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.11431,"AVALU":"U/L","BASE2":29.11431,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-16 15:51:53","ADY":552,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-113","SUBJID":"id-113","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.86591,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-06","TRTSDTM":"2021-01-10 15:51:53","TRTEDTM":"2024-01-11 09:51:53","TRT01SDTM":"2021-01-10 15:51:53","TRT01EDTM":"2023-01-11 03:51:53","TRT02SDTM":"2023-01-11 03:51:53","TRT02EDTM":"2024-01-11 09:51:53","AP01SDTM":"2021-01-10 15:51:53","AP01EDTM":"2023-01-11 03:51:53","AP02SDTM":"2023-01-11 03:51:53","AP02EDTM":"2024-01-11 09:51:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-11","EOSDY":1096,"LSTALVDT":"2024-02-03","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6029,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.71935,"AVALU":"U/L","BASE2":29.11431,"BASE":29.71935,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.60504,"PCHG2":2.07817,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-25 15:51:53","ADY":592,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-113","SUBJID":"id-113","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.86591,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-06","TRTSDTM":"2021-01-10 15:51:53","TRTEDTM":"2024-01-11 09:51:53","TRT01SDTM":"2021-01-10 15:51:53","TRT01EDTM":"2023-01-11 03:51:53","TRT02SDTM":"2023-01-11 03:51:53","TRT02EDTM":"2024-01-11 09:51:53","AP01SDTM":"2021-01-10 15:51:53","AP01EDTM":"2023-01-11 03:51:53","AP02SDTM":"2023-01-11 03:51:53","AP02EDTM":"2024-01-11 09:51:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-11","EOSDY":1096,"LSTALVDT":"2024-02-03","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7674,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.46665,"AVALU":"U/L","BASE2":29.11431,"BASE":29.71935,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.64766,"PCHG2":-46.87614,"CHG":-14.25271,"PCHG":-47.95766,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-13 15:51:53","ADY":641,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-113","SUBJID":"id-113","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.86591,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-06","TRTSDTM":"2021-01-10 15:51:53","TRTEDTM":"2024-01-11 09:51:53","TRT01SDTM":"2021-01-10 15:51:53","TRT01EDTM":"2023-01-11 03:51:53","TRT02SDTM":"2023-01-11 03:51:53","TRT02EDTM":"2024-01-11 09:51:53","AP01SDTM":"2021-01-10 15:51:53","AP01EDTM":"2023-01-11 03:51:53","AP02SDTM":"2023-01-11 03:51:53","AP02EDTM":"2024-01-11 09:51:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-11","EOSDY":1096,"LSTALVDT":"2024-02-03","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7109,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.97829,"AVALU":"U/L","BASE2":29.11431,"BASE":29.71935,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-23.13602,"PCHG2":-79.46614,"CHG":-23.74106,"PCHG":-79.88418,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-12-01 15:51:53","ADY":690,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-113","SUBJID":"id-113","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.86591,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-06","TRTSDTM":"2021-01-10 15:51:53","TRTEDTM":"2024-01-11 09:51:53","TRT01SDTM":"2021-01-10 15:51:53","TRT01EDTM":"2023-01-11 03:51:53","TRT02SDTM":"2023-01-11 03:51:53","TRT02EDTM":"2024-01-11 09:51:53","AP01SDTM":"2021-01-10 15:51:53","AP01EDTM":"2023-01-11 03:51:53","AP02SDTM":"2023-01-11 03:51:53","AP02EDTM":"2024-01-11 09:51:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-11","EOSDY":1096,"LSTALVDT":"2024-02-03","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5463,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":36.62521,"AVALU":"U/L","BASE2":29.11431,"BASE":29.71935,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.5109,"PCHG2":25.79795,"CHG":6.90585,"PCHG":23.23688,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-14 15:51:53","ADY":977,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-113","SUBJID":"id-113","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.86591,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-06","TRTSDTM":"2021-01-10 15:51:53","TRTEDTM":"2024-01-11 09:51:53","TRT01SDTM":"2021-01-10 15:51:53","TRT01EDTM":"2023-01-11 03:51:53","TRT02SDTM":"2023-01-11 03:51:53","TRT02EDTM":"2024-01-11 09:51:53","AP01SDTM":"2021-01-10 15:51:53","AP01EDTM":"2023-01-11 03:51:53","AP02SDTM":"2023-01-11 03:51:53","AP02EDTM":"2024-01-11 09:51:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-11","EOSDY":1096,"LSTALVDT":"2024-02-03","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5138,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.27028,"AVALU":"U/L","BASE2":29.11431,"BASE":29.71935,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.84403,"PCHG2":-2.89903,"CHG":-1.44907,"PCHG":-4.87586,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-22 15:51:53","ADY":985,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-113","SUBJID":"id-113","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.86591,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-06","TRTSDTM":"2021-01-10 15:51:53","TRTEDTM":"2024-01-11 09:51:53","TRT01SDTM":"2021-01-10 15:51:53","TRT01EDTM":"2023-01-11 03:51:53","TRT02SDTM":"2023-01-11 03:51:53","TRT02EDTM":"2024-01-11 09:51:53","AP01SDTM":"2021-01-10 15:51:53","AP01EDTM":"2023-01-11 03:51:53","AP02SDTM":"2023-01-11 03:51:53","AP02EDTM":"2024-01-11 09:51:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-11","EOSDY":1096,"LSTALVDT":"2024-02-03","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5876,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.25903,"AVALU":"U/L","BASE2":29.11431,"BASE":29.71935,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-18.85529,"PCHG2":-64.76295,"CHG":-19.46033,"PCHG":-65.48032,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-12-07 15:51:53","ADY":1061,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-113","SUBJID":"id-113","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.86591,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-06","TRTSDTM":"2021-01-10 15:51:53","TRTEDTM":"2024-01-11 09:51:53","TRT01SDTM":"2021-01-10 15:51:53","TRT01EDTM":"2023-01-11 03:51:53","TRT02SDTM":"2023-01-11 03:51:53","TRT02EDTM":"2024-01-11 09:51:53","AP01SDTM":"2021-01-10 15:51:53","AP01EDTM":"2023-01-11 03:51:53","AP02SDTM":"2023-01-11 03:51:53","AP02EDTM":"2024-01-11 09:51:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-11","EOSDY":1096,"LSTALVDT":"2024-02-03","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":715,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.05668,"AVALU":"mg/L","BASE2":9.05668,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-16 15:51:53","ADY":552,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-113","SUBJID":"id-113","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.86591,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-06","TRTSDTM":"2021-01-10 15:51:53","TRTEDTM":"2024-01-11 09:51:53","TRT01SDTM":"2021-01-10 15:51:53","TRT01EDTM":"2023-01-11 03:51:53","TRT02SDTM":"2023-01-11 03:51:53","TRT02EDTM":"2024-01-11 09:51:53","AP01SDTM":"2021-01-10 15:51:53","AP01EDTM":"2023-01-11 03:51:53","AP02SDTM":"2023-01-11 03:51:53","AP02EDTM":"2024-01-11 09:51:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-11","EOSDY":1096,"LSTALVDT":"2024-02-03","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4522,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.38354,"AVALU":"mg/L","BASE2":9.05668,"BASE":9.38354,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.32686,"PCHG2":3.60907,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-25 15:51:53","ADY":592,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-113","SUBJID":"id-113","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.86591,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-06","TRTSDTM":"2021-01-10 15:51:53","TRTEDTM":"2024-01-11 09:51:53","TRT01SDTM":"2021-01-10 15:51:53","TRT01EDTM":"2023-01-11 03:51:53","TRT02SDTM":"2023-01-11 03:51:53","TRT02EDTM":"2024-01-11 09:51:53","AP01SDTM":"2021-01-10 15:51:53","AP01EDTM":"2023-01-11 03:51:53","AP02SDTM":"2023-01-11 03:51:53","AP02EDTM":"2024-01-11 09:51:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-11","EOSDY":1096,"LSTALVDT":"2024-02-03","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7955,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.05704,"AVALU":"mg/L","BASE2":9.05668,"BASE":9.38354,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.99965,"PCHG2":-11.03767,"CHG":-1.32651,"PCHG":-14.13654,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-13 15:51:53","ADY":641,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-113","SUBJID":"id-113","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.86591,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-06","TRTSDTM":"2021-01-10 15:51:53","TRTEDTM":"2024-01-11 09:51:53","TRT01SDTM":"2021-01-10 15:51:53","TRT01EDTM":"2023-01-11 03:51:53","TRT02SDTM":"2023-01-11 03:51:53","TRT02EDTM":"2024-01-11 09:51:53","AP01SDTM":"2021-01-10 15:51:53","AP01EDTM":"2023-01-11 03:51:53","AP02SDTM":"2023-01-11 03:51:53","AP02EDTM":"2024-01-11 09:51:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-11","EOSDY":1096,"LSTALVDT":"2024-02-03","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":371,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.53113,"AVALU":"mg/L","BASE2":9.05668,"BASE":9.38354,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.52555,"PCHG2":-5.80289,"CHG":-0.85241,"PCHG":-9.0841,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-01 15:51:53","ADY":690,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-113","SUBJID":"id-113","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.86591,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-06","TRTSDTM":"2021-01-10 15:51:53","TRTEDTM":"2024-01-11 09:51:53","TRT01SDTM":"2021-01-10 15:51:53","TRT01EDTM":"2023-01-11 03:51:53","TRT02SDTM":"2023-01-11 03:51:53","TRT02EDTM":"2024-01-11 09:51:53","AP01SDTM":"2021-01-10 15:51:53","AP01EDTM":"2023-01-11 03:51:53","AP02SDTM":"2023-01-11 03:51:53","AP02EDTM":"2024-01-11 09:51:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-11","EOSDY":1096,"LSTALVDT":"2024-02-03","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3117,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.54111,"AVALU":"mg/L","BASE2":9.05668,"BASE":9.38354,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.51557,"PCHG2":-16.73432,"CHG":-1.84244,"PCHG":-19.63475,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2023-09-14 15:51:53","ADY":977,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-113","SUBJID":"id-113","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.86591,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-06","TRTSDTM":"2021-01-10 15:51:53","TRTEDTM":"2024-01-11 09:51:53","TRT01SDTM":"2021-01-10 15:51:53","TRT01EDTM":"2023-01-11 03:51:53","TRT02SDTM":"2023-01-11 03:51:53","TRT02EDTM":"2024-01-11 09:51:53","AP01SDTM":"2021-01-10 15:51:53","AP01EDTM":"2023-01-11 03:51:53","AP02SDTM":"2023-01-11 03:51:53","AP02EDTM":"2024-01-11 09:51:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-11","EOSDY":1096,"LSTALVDT":"2024-02-03","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2656,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.95825,"AVALU":"mg/L","BASE2":9.05668,"BASE":9.38354,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.90156,"PCHG2":32.03781,"CHG":2.5747,"PCHG":27.43846,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2023-09-22 15:51:53","ADY":985,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-113","SUBJID":"id-113","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.86591,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-06","TRTSDTM":"2021-01-10 15:51:53","TRTEDTM":"2024-01-11 09:51:53","TRT01SDTM":"2021-01-10 15:51:53","TRT01EDTM":"2023-01-11 03:51:53","TRT02SDTM":"2023-01-11 03:51:53","TRT02EDTM":"2024-01-11 09:51:53","AP01SDTM":"2021-01-10 15:51:53","AP01EDTM":"2023-01-11 03:51:53","AP02SDTM":"2023-01-11 03:51:53","AP02EDTM":"2024-01-11 09:51:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-11","EOSDY":1096,"LSTALVDT":"2024-02-03","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":436,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.25933,"AVALU":"mg/L","BASE2":9.05668,"BASE":9.38354,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.79735,"PCHG2":-19.84558,"CHG":-2.12421,"PCHG":-22.63764,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2023-12-07 15:51:53","ADY":1061,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-113","SUBJID":"id-113","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.86591,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-06","TRTSDTM":"2021-01-10 15:51:53","TRTEDTM":"2024-01-11 09:51:53","TRT01SDTM":"2021-01-10 15:51:53","TRT01EDTM":"2023-01-11 03:51:53","TRT02SDTM":"2023-01-11 03:51:53","TRT02EDTM":"2024-01-11 09:51:53","AP01SDTM":"2021-01-10 15:51:53","AP01EDTM":"2023-01-11 03:51:53","AP02SDTM":"2023-01-11 03:51:53","AP02EDTM":"2024-01-11 09:51:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-11","EOSDY":1096,"LSTALVDT":"2024-02-03","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1037,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93612,"AVALU":"g/L","BASE2":2.93612,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-16 15:51:53","ADY":552,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-113","SUBJID":"id-113","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.86591,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-06","TRTSDTM":"2021-01-10 15:51:53","TRTEDTM":"2024-01-11 09:51:53","TRT01SDTM":"2021-01-10 15:51:53","TRT01EDTM":"2023-01-11 03:51:53","TRT02SDTM":"2023-01-11 03:51:53","TRT02EDTM":"2024-01-11 09:51:53","AP01SDTM":"2021-01-10 15:51:53","AP01EDTM":"2023-01-11 03:51:53","AP02SDTM":"2023-01-11 03:51:53","AP02EDTM":"2024-01-11 09:51:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-11","EOSDY":1096,"LSTALVDT":"2024-02-03","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":530,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74311,"AVALU":"g/L","BASE2":2.93612,"BASE":2.74311,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.19301,"PCHG2":-6.57363,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-25 15:51:53","ADY":592,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-113","SUBJID":"id-113","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.86591,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-06","TRTSDTM":"2021-01-10 15:51:53","TRTEDTM":"2024-01-11 09:51:53","TRT01SDTM":"2021-01-10 15:51:53","TRT01EDTM":"2023-01-11 03:51:53","TRT02SDTM":"2023-01-11 03:51:53","TRT02EDTM":"2024-01-11 09:51:53","AP01SDTM":"2021-01-10 15:51:53","AP01EDTM":"2023-01-11 03:51:53","AP02SDTM":"2023-01-11 03:51:53","AP02EDTM":"2024-01-11 09:51:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-11","EOSDY":1096,"LSTALVDT":"2024-02-03","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4942,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05678,"AVALU":"g/L","BASE2":2.93612,"BASE":2.74311,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12066,"PCHG2":4.10965,"CHG":0.31367,"PCHG":11.43497,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-10-13 15:51:53","ADY":641,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-113","SUBJID":"id-113","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.86591,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-06","TRTSDTM":"2021-01-10 15:51:53","TRTEDTM":"2024-01-11 09:51:53","TRT01SDTM":"2021-01-10 15:51:53","TRT01EDTM":"2023-01-11 03:51:53","TRT02SDTM":"2023-01-11 03:51:53","TRT02EDTM":"2024-01-11 09:51:53","AP01SDTM":"2021-01-10 15:51:53","AP01EDTM":"2023-01-11 03:51:53","AP02SDTM":"2023-01-11 03:51:53","AP02EDTM":"2024-01-11 09:51:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-11","EOSDY":1096,"LSTALVDT":"2024-02-03","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6736,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85826,"AVALU":"g/L","BASE2":2.93612,"BASE":2.74311,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07786,"PCHG2":-2.65187,"CHG":0.11515,"PCHG":4.19771,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-01 15:51:53","ADY":690,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-113","SUBJID":"id-113","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.86591,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-06","TRTSDTM":"2021-01-10 15:51:53","TRTEDTM":"2024-01-11 09:51:53","TRT01SDTM":"2021-01-10 15:51:53","TRT01EDTM":"2023-01-11 03:51:53","TRT02SDTM":"2023-01-11 03:51:53","TRT02EDTM":"2024-01-11 09:51:53","AP01SDTM":"2021-01-10 15:51:53","AP01EDTM":"2023-01-11 03:51:53","AP02SDTM":"2023-01-11 03:51:53","AP02EDTM":"2024-01-11 09:51:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-11","EOSDY":1096,"LSTALVDT":"2024-02-03","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5183,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86817,"AVALU":"g/L","BASE2":2.93612,"BASE":2.74311,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06795,"PCHG2":-2.31441,"CHG":0.12506,"PCHG":4.55891,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-14 15:51:53","ADY":977,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-113","SUBJID":"id-113","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.86591,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-06","TRTSDTM":"2021-01-10 15:51:53","TRTEDTM":"2024-01-11 09:51:53","TRT01SDTM":"2021-01-10 15:51:53","TRT01EDTM":"2023-01-11 03:51:53","TRT02SDTM":"2023-01-11 03:51:53","TRT02EDTM":"2024-01-11 09:51:53","AP01SDTM":"2021-01-10 15:51:53","AP01EDTM":"2023-01-11 03:51:53","AP02SDTM":"2023-01-11 03:51:53","AP02EDTM":"2024-01-11 09:51:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-11","EOSDY":1096,"LSTALVDT":"2024-02-03","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7754,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9152,"AVALU":"g/L","BASE2":2.93612,"BASE":2.74311,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02092,"PCHG2":-0.71256,"CHG":0.17209,"PCHG":6.27347,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-22 15:51:53","ADY":985,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-113","SUBJID":"id-113","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.86591,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-06","TRTSDTM":"2021-01-10 15:51:53","TRTEDTM":"2024-01-11 09:51:53","TRT01SDTM":"2021-01-10 15:51:53","TRT01EDTM":"2023-01-11 03:51:53","TRT02SDTM":"2023-01-11 03:51:53","TRT02EDTM":"2024-01-11 09:51:53","AP01SDTM":"2021-01-10 15:51:53","AP01EDTM":"2023-01-11 03:51:53","AP02SDTM":"2023-01-11 03:51:53","AP02EDTM":"2024-01-11 09:51:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-11","EOSDY":1096,"LSTALVDT":"2024-02-03","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6482,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95226,"AVALU":"g/L","BASE2":2.93612,"BASE":2.74311,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01614,"PCHG2":0.5498,"CHG":0.20915,"PCHG":7.62465,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-12-07 15:51:53","ADY":1061,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-116","SUBJID":"id-116","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.31633,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-15 19:01:41","TRTEDTM":"2022-02-14 05:02:48","TRT01SDTM":"2020-03-15 19:01:41","TRT01EDTM":"2021-02-13 23:02:48","TRT02SDTM":"2021-02-13 23:02:48","TRT02EDTM":"2022-02-14 05:02:48","AP01SDTM":"2020-03-15 19:01:41","AP01EDTM":"2021-02-13 23:02:48","AP02SDTM":"2021-02-13 23:02:48","AP02EDTM":"2022-02-14 05:02:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":701,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7185,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.697,"AVALU":"U/L","BASE2":11.697,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-22 19:01:41","ADY":68,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-116","SUBJID":"id-116","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.31633,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-15 19:01:41","TRTEDTM":"2022-02-14 05:02:48","TRT01SDTM":"2020-03-15 19:01:41","TRT01EDTM":"2021-02-13 23:02:48","TRT02SDTM":"2021-02-13 23:02:48","TRT02EDTM":"2022-02-14 05:02:48","AP01SDTM":"2020-03-15 19:01:41","AP01EDTM":"2021-02-13 23:02:48","AP02SDTM":"2021-02-13 23:02:48","AP02EDTM":"2022-02-14 05:02:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":701,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4637,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":36.79636,"AVALU":"U/L","BASE2":11.697,"BASE":36.79636,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":25.09936,"PCHG2":214.57953,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-12 19:01:41","ADY":181,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-116","SUBJID":"id-116","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.31633,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-15 19:01:41","TRTEDTM":"2022-02-14 05:02:48","TRT01SDTM":"2020-03-15 19:01:41","TRT01EDTM":"2021-02-13 23:02:48","TRT02SDTM":"2021-02-13 23:02:48","TRT02EDTM":"2022-02-14 05:02:48","AP01SDTM":"2020-03-15 19:01:41","AP01EDTM":"2021-02-13 23:02:48","AP02SDTM":"2021-02-13 23:02:48","AP02EDTM":"2022-02-14 05:02:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":701,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5757,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":35.5622,"AVALU":"U/L","BASE2":11.697,"BASE":36.79636,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":23.8652,"PCHG2":204.02844,"CHG":-1.23416,"PCHG":-3.35403,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-09 19:01:41","ADY":269,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-116","SUBJID":"id-116","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.31633,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-15 19:01:41","TRTEDTM":"2022-02-14 05:02:48","TRT01SDTM":"2020-03-15 19:01:41","TRT01EDTM":"2021-02-13 23:02:48","TRT02SDTM":"2021-02-13 23:02:48","TRT02EDTM":"2022-02-14 05:02:48","AP01SDTM":"2020-03-15 19:01:41","AP01EDTM":"2021-02-13 23:02:48","AP02SDTM":"2021-02-13 23:02:48","AP02EDTM":"2022-02-14 05:02:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":701,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":380,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.02675,"AVALU":"U/L","BASE2":11.697,"BASE":36.79636,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.67025,"PCHG2":-22.82851,"CHG":-27.76961,"PCHG":-75.46837,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-12 19:01:41","ADY":423,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-116","SUBJID":"id-116","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.31633,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-15 19:01:41","TRTEDTM":"2022-02-14 05:02:48","TRT01SDTM":"2020-03-15 19:01:41","TRT01EDTM":"2021-02-13 23:02:48","TRT02SDTM":"2021-02-13 23:02:48","TRT02EDTM":"2022-02-14 05:02:48","AP01SDTM":"2020-03-15 19:01:41","AP01EDTM":"2021-02-13 23:02:48","AP02SDTM":"2021-02-13 23:02:48","AP02EDTM":"2022-02-14 05:02:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":701,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2055,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.53707,"AVALU":"U/L","BASE2":11.697,"BASE":36.79636,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.84007,"PCHG2":169.61679,"CHG":-5.25929,"PCHG":-14.29297,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-28 19:01:41","ADY":439,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-116","SUBJID":"id-116","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.31633,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-15 19:01:41","TRTEDTM":"2022-02-14 05:02:48","TRT01SDTM":"2020-03-15 19:01:41","TRT01EDTM":"2021-02-13 23:02:48","TRT02SDTM":"2021-02-13 23:02:48","TRT02EDTM":"2022-02-14 05:02:48","AP01SDTM":"2020-03-15 19:01:41","AP01EDTM":"2021-02-13 23:02:48","AP02SDTM":"2021-02-13 23:02:48","AP02EDTM":"2022-02-14 05:02:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":701,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8238,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.69867,"AVALU":"U/L","BASE2":11.697,"BASE":36.79636,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.99833,"PCHG2":-51.28091,"CHG":-31.09769,"PCHG":-84.51295,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-09-28 19:01:41","ADY":562,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-116","SUBJID":"id-116","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.31633,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-15 19:01:41","TRTEDTM":"2022-02-14 05:02:48","TRT01SDTM":"2020-03-15 19:01:41","TRT01EDTM":"2021-02-13 23:02:48","TRT02SDTM":"2021-02-13 23:02:48","TRT02EDTM":"2022-02-14 05:02:48","AP01SDTM":"2020-03-15 19:01:41","AP01EDTM":"2021-02-13 23:02:48","AP02SDTM":"2021-02-13 23:02:48","AP02EDTM":"2022-02-14 05:02:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":701,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4517,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.60362,"AVALU":"U/L","BASE2":11.697,"BASE":36.79636,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.09337,"PCHG2":-17.89667,"CHG":-27.19273,"PCHG":-73.90061,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-30 19:01:41","ADY":625,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-116","SUBJID":"id-116","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.31633,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-15 19:01:41","TRTEDTM":"2022-02-14 05:02:48","TRT01SDTM":"2020-03-15 19:01:41","TRT01EDTM":"2021-02-13 23:02:48","TRT02SDTM":"2021-02-13 23:02:48","TRT02EDTM":"2022-02-14 05:02:48","AP01SDTM":"2020-03-15 19:01:41","AP01EDTM":"2021-02-13 23:02:48","AP02SDTM":"2021-02-13 23:02:48","AP02EDTM":"2022-02-14 05:02:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":701,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3594,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.50694,"AVALU":"mg/L","BASE2":9.50694,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-05-22 19:01:41","ADY":68,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-116","SUBJID":"id-116","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.31633,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-15 19:01:41","TRTEDTM":"2022-02-14 05:02:48","TRT01SDTM":"2020-03-15 19:01:41","TRT01EDTM":"2021-02-13 23:02:48","TRT02SDTM":"2021-02-13 23:02:48","TRT02EDTM":"2022-02-14 05:02:48","AP01SDTM":"2020-03-15 19:01:41","AP01EDTM":"2021-02-13 23:02:48","AP02SDTM":"2021-02-13 23:02:48","AP02EDTM":"2022-02-14 05:02:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":701,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6347,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.21489,"AVALU":"mg/L","BASE2":9.50694,"BASE":6.21489,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-3.29205,"PCHG2":-34.62789,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2020-09-12 19:01:41","ADY":181,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-116","SUBJID":"id-116","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.31633,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-15 19:01:41","TRTEDTM":"2022-02-14 05:02:48","TRT01SDTM":"2020-03-15 19:01:41","TRT01EDTM":"2021-02-13 23:02:48","TRT02SDTM":"2021-02-13 23:02:48","TRT02EDTM":"2022-02-14 05:02:48","AP01SDTM":"2020-03-15 19:01:41","AP01EDTM":"2021-02-13 23:02:48","AP02SDTM":"2021-02-13 23:02:48","AP02EDTM":"2022-02-14 05:02:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":701,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7591,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.69973,"AVALU":"mg/L","BASE2":9.50694,"BASE":6.21489,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.19278,"PCHG2":2.02781,"CHG":3.48484,"PCHG":56.07237,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-12-09 19:01:41","ADY":269,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-116","SUBJID":"id-116","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.31633,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-15 19:01:41","TRTEDTM":"2022-02-14 05:02:48","TRT01SDTM":"2020-03-15 19:01:41","TRT01EDTM":"2021-02-13 23:02:48","TRT02SDTM":"2021-02-13 23:02:48","TRT02EDTM":"2022-02-14 05:02:48","AP01SDTM":"2020-03-15 19:01:41","AP01EDTM":"2021-02-13 23:02:48","AP02SDTM":"2021-02-13 23:02:48","AP02EDTM":"2022-02-14 05:02:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":701,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2953,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.41427,"AVALU":"mg/L","BASE2":9.50694,"BASE":6.21489,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09267,"PCHG2":-0.97475,"CHG":3.19938,"PCHG":51.47934,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-05-12 19:01:41","ADY":423,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-116","SUBJID":"id-116","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.31633,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-15 19:01:41","TRTEDTM":"2022-02-14 05:02:48","TRT01SDTM":"2020-03-15 19:01:41","TRT01EDTM":"2021-02-13 23:02:48","TRT02SDTM":"2021-02-13 23:02:48","TRT02EDTM":"2022-02-14 05:02:48","AP01SDTM":"2020-03-15 19:01:41","AP01EDTM":"2021-02-13 23:02:48","AP02SDTM":"2021-02-13 23:02:48","AP02EDTM":"2022-02-14 05:02:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":701,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5887,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.2037,"AVALU":"mg/L","BASE2":9.50694,"BASE":6.21489,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.30324,"PCHG2":-3.18971,"CHG":2.98881,"PCHG":48.09112,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-05-28 19:01:41","ADY":439,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-116","SUBJID":"id-116","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.31633,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-15 19:01:41","TRTEDTM":"2022-02-14 05:02:48","TRT01SDTM":"2020-03-15 19:01:41","TRT01EDTM":"2021-02-13 23:02:48","TRT02SDTM":"2021-02-13 23:02:48","TRT02EDTM":"2022-02-14 05:02:48","AP01SDTM":"2020-03-15 19:01:41","AP01EDTM":"2021-02-13 23:02:48","AP02SDTM":"2021-02-13 23:02:48","AP02EDTM":"2022-02-14 05:02:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":701,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6914,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.36432,"AVALU":"mg/L","BASE2":9.50694,"BASE":6.21489,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.85738,"PCHG2":9.01843,"CHG":4.14943,"PCHG":66.76595,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"2","BTOXGR":"-2","ADTM":"2021-09-28 19:01:41","ADY":562,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-116","SUBJID":"id-116","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.31633,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-15 19:01:41","TRTEDTM":"2022-02-14 05:02:48","TRT01SDTM":"2020-03-15 19:01:41","TRT01EDTM":"2021-02-13 23:02:48","TRT02SDTM":"2021-02-13 23:02:48","TRT02EDTM":"2022-02-14 05:02:48","AP01SDTM":"2020-03-15 19:01:41","AP01EDTM":"2021-02-13 23:02:48","AP02SDTM":"2021-02-13 23:02:48","AP02EDTM":"2022-02-14 05:02:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":701,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1019,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.7233,"AVALU":"mg/L","BASE2":9.50694,"BASE":6.21489,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.21636,"PCHG2":2.27581,"CHG":3.50841,"PCHG":56.45175,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-11-30 19:01:41","ADY":625,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-116","SUBJID":"id-116","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.31633,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-15 19:01:41","TRTEDTM":"2022-02-14 05:02:48","TRT01SDTM":"2020-03-15 19:01:41","TRT01EDTM":"2021-02-13 23:02:48","TRT02SDTM":"2021-02-13 23:02:48","TRT02EDTM":"2022-02-14 05:02:48","AP01SDTM":"2020-03-15 19:01:41","AP01EDTM":"2021-02-13 23:02:48","AP02SDTM":"2021-02-13 23:02:48","AP02EDTM":"2022-02-14 05:02:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":701,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2039,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99461,"AVALU":"g/L","BASE2":2.99461,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-22 19:01:41","ADY":68,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-116","SUBJID":"id-116","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.31633,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-15 19:01:41","TRTEDTM":"2022-02-14 05:02:48","TRT01SDTM":"2020-03-15 19:01:41","TRT01EDTM":"2021-02-13 23:02:48","TRT02SDTM":"2021-02-13 23:02:48","TRT02EDTM":"2022-02-14 05:02:48","AP01SDTM":"2020-03-15 19:01:41","AP01EDTM":"2021-02-13 23:02:48","AP02SDTM":"2021-02-13 23:02:48","AP02EDTM":"2022-02-14 05:02:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":701,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8077,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86922,"AVALU":"g/L","BASE2":2.99461,"BASE":2.86922,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.12539,"PCHG2":-4.18712,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-12 19:01:41","ADY":181,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-116","SUBJID":"id-116","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.31633,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-15 19:01:41","TRTEDTM":"2022-02-14 05:02:48","TRT01SDTM":"2020-03-15 19:01:41","TRT01EDTM":"2021-02-13 23:02:48","TRT02SDTM":"2021-02-13 23:02:48","TRT02EDTM":"2022-02-14 05:02:48","AP01SDTM":"2020-03-15 19:01:41","AP01EDTM":"2021-02-13 23:02:48","AP02SDTM":"2021-02-13 23:02:48","AP02EDTM":"2022-02-14 05:02:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":701,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5320,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93511,"AVALU":"g/L","BASE2":2.99461,"BASE":2.86922,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0595,"PCHG2":-1.98678,"CHG":0.06589,"PCHG":2.29649,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-09 19:01:41","ADY":269,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-116","SUBJID":"id-116","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.31633,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-15 19:01:41","TRTEDTM":"2022-02-14 05:02:48","TRT01SDTM":"2020-03-15 19:01:41","TRT01EDTM":"2021-02-13 23:02:48","TRT02SDTM":"2021-02-13 23:02:48","TRT02EDTM":"2022-02-14 05:02:48","AP01SDTM":"2020-03-15 19:01:41","AP01EDTM":"2021-02-13 23:02:48","AP02SDTM":"2021-02-13 23:02:48","AP02EDTM":"2022-02-14 05:02:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":701,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6185,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84835,"AVALU":"g/L","BASE2":2.99461,"BASE":2.86922,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14626,"PCHG2":-4.88402,"CHG":-0.02087,"PCHG":-0.72736,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-12 19:01:41","ADY":423,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-116","SUBJID":"id-116","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.31633,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-15 19:01:41","TRTEDTM":"2022-02-14 05:02:48","TRT01SDTM":"2020-03-15 19:01:41","TRT01EDTM":"2021-02-13 23:02:48","TRT02SDTM":"2021-02-13 23:02:48","TRT02EDTM":"2022-02-14 05:02:48","AP01SDTM":"2020-03-15 19:01:41","AP01EDTM":"2021-02-13 23:02:48","AP02SDTM":"2021-02-13 23:02:48","AP02EDTM":"2022-02-14 05:02:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":701,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6205,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79859,"AVALU":"g/L","BASE2":2.99461,"BASE":2.86922,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19602,"PCHG2":-6.54575,"CHG":-0.07063,"PCHG":-2.4617,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-28 19:01:41","ADY":439,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-116","SUBJID":"id-116","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.31633,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-15 19:01:41","TRTEDTM":"2022-02-14 05:02:48","TRT01SDTM":"2020-03-15 19:01:41","TRT01EDTM":"2021-02-13 23:02:48","TRT02SDTM":"2021-02-13 23:02:48","TRT02EDTM":"2022-02-14 05:02:48","AP01SDTM":"2020-03-15 19:01:41","AP01EDTM":"2021-02-13 23:02:48","AP02SDTM":"2021-02-13 23:02:48","AP02EDTM":"2022-02-14 05:02:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":701,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6871,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95472,"AVALU":"g/L","BASE2":2.99461,"BASE":2.86922,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03989,"PCHG2":-1.33202,"CHG":0.0855,"PCHG":2.97987,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-28 19:01:41","ADY":562,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-116","SUBJID":"id-116","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.31633,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-15 19:01:41","TRTEDTM":"2022-02-14 05:02:48","TRT01SDTM":"2020-03-15 19:01:41","TRT01EDTM":"2021-02-13 23:02:48","TRT02SDTM":"2021-02-13 23:02:48","TRT02EDTM":"2022-02-14 05:02:48","AP01SDTM":"2020-03-15 19:01:41","AP01EDTM":"2021-02-13 23:02:48","AP02SDTM":"2021-02-13 23:02:48","AP02EDTM":"2022-02-14 05:02:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":701,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-13","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8125,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90695,"AVALU":"g/L","BASE2":2.99461,"BASE":2.86922,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08766,"PCHG2":-2.92727,"CHG":0.03773,"PCHG":1.31491,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-30 19:01:41","ADY":625,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-124","SUBJID":"id-124","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36798,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-12","TRTSDTM":"2019-07-14 08:51:46","TRTEDTM":"2022-07-14 02:51:46","TRT01SDTM":"2019-07-14 08:51:46","TRT01EDTM":"2021-07-13 20:51:46","TRT02SDTM":"2021-07-13 20:51:46","TRT02EDTM":"2022-07-14 02:51:46","AP01SDTM":"2019-07-14 08:51:46","AP01EDTM":"2021-07-13 20:51:46","AP02SDTM":"2021-07-13 20:51:46","AP02EDTM":"2022-07-14 02:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-14","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2901,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.56727,"AVALU":"U/L","BASE2":10.56727,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-24 08:51:46","ADY":133,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-124","SUBJID":"id-124","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36798,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-12","TRTSDTM":"2019-07-14 08:51:46","TRTEDTM":"2022-07-14 02:51:46","TRT01SDTM":"2019-07-14 08:51:46","TRT01EDTM":"2021-07-13 20:51:46","TRT02SDTM":"2021-07-13 20:51:46","TRT02EDTM":"2022-07-14 02:51:46","AP01SDTM":"2019-07-14 08:51:46","AP01EDTM":"2021-07-13 20:51:46","AP02SDTM":"2021-07-13 20:51:46","AP02EDTM":"2022-07-14 02:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-14","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":475,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.85209,"AVALU":"U/L","BASE2":10.56727,"BASE":13.85209,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":3.28483,"PCHG2":31.08492,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-30 08:51:46","ADY":169,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-124","SUBJID":"id-124","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36798,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-12","TRTSDTM":"2019-07-14 08:51:46","TRTEDTM":"2022-07-14 02:51:46","TRT01SDTM":"2019-07-14 08:51:46","TRT01EDTM":"2021-07-13 20:51:46","TRT02SDTM":"2021-07-13 20:51:46","TRT02EDTM":"2022-07-14 02:51:46","AP01SDTM":"2019-07-14 08:51:46","AP01EDTM":"2021-07-13 20:51:46","AP02SDTM":"2021-07-13 20:51:46","AP02EDTM":"2022-07-14 02:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-14","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2982,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.34831,"AVALU":"U/L","BASE2":10.56727,"BASE":13.85209,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":21.78104,"PCHG2":206.11799,"CHG":18.49621,"PCHG":133.52648,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-23 08:51:46","ADY":224,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-124","SUBJID":"id-124","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36798,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-12","TRTSDTM":"2019-07-14 08:51:46","TRTEDTM":"2022-07-14 02:51:46","TRT01SDTM":"2019-07-14 08:51:46","TRT01EDTM":"2021-07-13 20:51:46","TRT02SDTM":"2021-07-13 20:51:46","TRT02EDTM":"2022-07-14 02:51:46","AP01SDTM":"2019-07-14 08:51:46","AP01EDTM":"2021-07-13 20:51:46","AP02SDTM":"2021-07-13 20:51:46","AP02EDTM":"2022-07-14 02:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-14","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":909,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.89703,"AVALU":"U/L","BASE2":10.56727,"BASE":13.85209,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.32976,"PCHG2":22.04694,"CHG":-0.95507,"PCHG":-6.89475,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-01 08:51:46","ADY":476,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-124","SUBJID":"id-124","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36798,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-12","TRTSDTM":"2019-07-14 08:51:46","TRTEDTM":"2022-07-14 02:51:46","TRT01SDTM":"2019-07-14 08:51:46","TRT01EDTM":"2021-07-13 20:51:46","TRT02SDTM":"2021-07-13 20:51:46","TRT02EDTM":"2022-07-14 02:51:46","AP01SDTM":"2019-07-14 08:51:46","AP01EDTM":"2021-07-13 20:51:46","AP02SDTM":"2021-07-13 20:51:46","AP02EDTM":"2022-07-14 02:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-14","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5962,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.82179,"AVALU":"U/L","BASE2":10.56727,"BASE":13.85209,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.74548,"PCHG2":-25.98098,"CHG":-6.03031,"PCHG":-43.53353,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-21 08:51:46","ADY":526,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-124","SUBJID":"id-124","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36798,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-12","TRTSDTM":"2019-07-14 08:51:46","TRTEDTM":"2022-07-14 02:51:46","TRT01SDTM":"2019-07-14 08:51:46","TRT01EDTM":"2021-07-13 20:51:46","TRT02SDTM":"2021-07-13 20:51:46","TRT02EDTM":"2022-07-14 02:51:46","AP01SDTM":"2019-07-14 08:51:46","AP01EDTM":"2021-07-13 20:51:46","AP02SDTM":"2021-07-13 20:51:46","AP02EDTM":"2022-07-14 02:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-14","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4060,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.0381,"AVALU":"U/L","BASE2":10.56727,"BASE":13.85209,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.52916,"PCHG2":-42.86031,"CHG":-7.81399,"PCHG":-56.41017,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-02-23 08:51:46","ADY":590,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-124","SUBJID":"id-124","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36798,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-12","TRTSDTM":"2019-07-14 08:51:46","TRTEDTM":"2022-07-14 02:51:46","TRT01SDTM":"2019-07-14 08:51:46","TRT01EDTM":"2021-07-13 20:51:46","TRT02SDTM":"2021-07-13 20:51:46","TRT02EDTM":"2022-07-14 02:51:46","AP01SDTM":"2019-07-14 08:51:46","AP01EDTM":"2021-07-13 20:51:46","AP02SDTM":"2021-07-13 20:51:46","AP02EDTM":"2022-07-14 02:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-14","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1097,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.55882,"AVALU":"U/L","BASE2":10.56727,"BASE":13.85209,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.99155,"PCHG2":189.18375,"CHG":16.70673,"PCHG":120.60795,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-12 08:51:46","ADY":944,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-124","SUBJID":"id-124","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36798,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-12","TRTSDTM":"2019-07-14 08:51:46","TRTEDTM":"2022-07-14 02:51:46","TRT01SDTM":"2019-07-14 08:51:46","TRT01EDTM":"2021-07-13 20:51:46","TRT02SDTM":"2021-07-13 20:51:46","TRT02EDTM":"2022-07-14 02:51:46","AP01SDTM":"2019-07-14 08:51:46","AP01EDTM":"2021-07-13 20:51:46","AP02SDTM":"2021-07-13 20:51:46","AP02EDTM":"2022-07-14 02:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-14","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4944,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.1634,"AVALU":"mg/L","BASE2":7.1634,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-4","BTOXGR":"0","ADTM":"2019-11-24 08:51:46","ADY":133,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-124","SUBJID":"id-124","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36798,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-12","TRTSDTM":"2019-07-14 08:51:46","TRTEDTM":"2022-07-14 02:51:46","TRT01SDTM":"2019-07-14 08:51:46","TRT01EDTM":"2021-07-13 20:51:46","TRT02SDTM":"2021-07-13 20:51:46","TRT02EDTM":"2022-07-14 02:51:46","AP01SDTM":"2019-07-14 08:51:46","AP01EDTM":"2021-07-13 20:51:46","AP02SDTM":"2021-07-13 20:51:46","AP02EDTM":"2022-07-14 02:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-14","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4078,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.7973,"AVALU":"mg/L","BASE2":7.1634,"BASE":9.7973,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.63391,"PCHG2":36.76898,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-30 08:51:46","ADY":169,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-124","SUBJID":"id-124","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36798,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-12","TRTSDTM":"2019-07-14 08:51:46","TRTEDTM":"2022-07-14 02:51:46","TRT01SDTM":"2019-07-14 08:51:46","TRT01EDTM":"2021-07-13 20:51:46","TRT02SDTM":"2021-07-13 20:51:46","TRT02EDTM":"2022-07-14 02:51:46","AP01SDTM":"2019-07-14 08:51:46","AP01EDTM":"2021-07-13 20:51:46","AP02SDTM":"2021-07-13 20:51:46","AP02EDTM":"2022-07-14 02:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-14","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":26,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.16427,"AVALU":"mg/L","BASE2":7.1634,"BASE":9.7973,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.00088,"PCHG2":27.93199,"CHG":-0.63303,"PCHG":-6.46125,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-23 08:51:46","ADY":224,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-124","SUBJID":"id-124","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36798,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-12","TRTSDTM":"2019-07-14 08:51:46","TRTEDTM":"2022-07-14 02:51:46","TRT01SDTM":"2019-07-14 08:51:46","TRT01EDTM":"2021-07-13 20:51:46","TRT02SDTM":"2021-07-13 20:51:46","TRT02EDTM":"2022-07-14 02:51:46","AP01SDTM":"2019-07-14 08:51:46","AP01EDTM":"2021-07-13 20:51:46","AP02SDTM":"2021-07-13 20:51:46","AP02EDTM":"2022-07-14 02:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-14","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6501,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.75385,"AVALU":"mg/L","BASE2":7.1634,"BASE":9.7973,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.59045,"PCHG2":8.24265,"CHG":-2.04345,"PCHG":-20.85731,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-11-01 08:51:46","ADY":476,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-124","SUBJID":"id-124","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36798,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-12","TRTSDTM":"2019-07-14 08:51:46","TRTEDTM":"2022-07-14 02:51:46","TRT01SDTM":"2019-07-14 08:51:46","TRT01EDTM":"2021-07-13 20:51:46","TRT02SDTM":"2021-07-13 20:51:46","TRT02EDTM":"2022-07-14 02:51:46","AP01SDTM":"2019-07-14 08:51:46","AP01EDTM":"2021-07-13 20:51:46","AP02SDTM":"2021-07-13 20:51:46","AP02EDTM":"2022-07-14 02:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-14","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3503,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.29443,"AVALU":"mg/L","BASE2":7.1634,"BASE":9.7973,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.13104,"PCHG2":43.70884,"CHG":0.49713,"PCHG":5.07415,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-12-21 08:51:46","ADY":526,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-124","SUBJID":"id-124","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36798,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-12","TRTSDTM":"2019-07-14 08:51:46","TRTEDTM":"2022-07-14 02:51:46","TRT01SDTM":"2019-07-14 08:51:46","TRT01EDTM":"2021-07-13 20:51:46","TRT02SDTM":"2021-07-13 20:51:46","TRT02EDTM":"2022-07-14 02:51:46","AP01SDTM":"2019-07-14 08:51:46","AP01EDTM":"2021-07-13 20:51:46","AP02SDTM":"2021-07-13 20:51:46","AP02EDTM":"2022-07-14 02:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-14","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5949,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.89802,"AVALU":"mg/L","BASE2":7.1634,"BASE":9.7973,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.73462,"PCHG2":10.25525,"CHG":-1.89928,"PCHG":-19.38577,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-02-23 08:51:46","ADY":590,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-124","SUBJID":"id-124","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36798,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-12","TRTSDTM":"2019-07-14 08:51:46","TRTEDTM":"2022-07-14 02:51:46","TRT01SDTM":"2019-07-14 08:51:46","TRT01EDTM":"2021-07-13 20:51:46","TRT02SDTM":"2021-07-13 20:51:46","TRT02EDTM":"2022-07-14 02:51:46","AP01SDTM":"2019-07-14 08:51:46","AP01EDTM":"2021-07-13 20:51:46","AP02SDTM":"2021-07-13 20:51:46","AP02EDTM":"2022-07-14 02:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-14","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1343,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.86028,"AVALU":"mg/L","BASE2":7.1634,"BASE":9.7973,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.69688,"PCHG2":51.60799,"CHG":1.06298,"PCHG":10.84969,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-02-12 08:51:46","ADY":944,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-124","SUBJID":"id-124","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36798,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-12","TRTSDTM":"2019-07-14 08:51:46","TRTEDTM":"2022-07-14 02:51:46","TRT01SDTM":"2019-07-14 08:51:46","TRT01EDTM":"2021-07-13 20:51:46","TRT02SDTM":"2021-07-13 20:51:46","TRT02EDTM":"2022-07-14 02:51:46","AP01SDTM":"2019-07-14 08:51:46","AP01EDTM":"2021-07-13 20:51:46","AP02SDTM":"2021-07-13 20:51:46","AP02EDTM":"2022-07-14 02:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-14","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8174,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93726,"AVALU":"g/L","BASE2":2.93726,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-24 08:51:46","ADY":133,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-124","SUBJID":"id-124","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36798,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-12","TRTSDTM":"2019-07-14 08:51:46","TRTEDTM":"2022-07-14 02:51:46","TRT01SDTM":"2019-07-14 08:51:46","TRT01EDTM":"2021-07-13 20:51:46","TRT02SDTM":"2021-07-13 20:51:46","TRT02EDTM":"2022-07-14 02:51:46","AP01SDTM":"2019-07-14 08:51:46","AP01EDTM":"2021-07-13 20:51:46","AP02SDTM":"2021-07-13 20:51:46","AP02EDTM":"2022-07-14 02:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-14","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2780,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77494,"AVALU":"g/L","BASE2":2.93726,"BASE":2.77494,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.16232,"PCHG2":-5.5263,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-30 08:51:46","ADY":169,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-124","SUBJID":"id-124","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36798,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-12","TRTSDTM":"2019-07-14 08:51:46","TRTEDTM":"2022-07-14 02:51:46","TRT01SDTM":"2019-07-14 08:51:46","TRT01EDTM":"2021-07-13 20:51:46","TRT02SDTM":"2021-07-13 20:51:46","TRT02EDTM":"2022-07-14 02:51:46","AP01SDTM":"2019-07-14 08:51:46","AP01EDTM":"2021-07-13 20:51:46","AP02SDTM":"2021-07-13 20:51:46","AP02EDTM":"2022-07-14 02:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-14","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3633,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03221,"AVALU":"g/L","BASE2":2.93726,"BASE":2.77494,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09495,"PCHG2":3.23268,"CHG":0.25727,"PCHG":9.27134,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-02-23 08:51:46","ADY":224,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-124","SUBJID":"id-124","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36798,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-12","TRTSDTM":"2019-07-14 08:51:46","TRTEDTM":"2022-07-14 02:51:46","TRT01SDTM":"2019-07-14 08:51:46","TRT01EDTM":"2021-07-13 20:51:46","TRT02SDTM":"2021-07-13 20:51:46","TRT02EDTM":"2022-07-14 02:51:46","AP01SDTM":"2019-07-14 08:51:46","AP01EDTM":"2021-07-13 20:51:46","AP02SDTM":"2021-07-13 20:51:46","AP02EDTM":"2022-07-14 02:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-14","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6612,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86254,"AVALU":"g/L","BASE2":2.93726,"BASE":2.77494,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07472,"PCHG2":-2.5437,"CHG":0.08761,"PCHG":3.15706,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-01 08:51:46","ADY":476,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-124","SUBJID":"id-124","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36798,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-12","TRTSDTM":"2019-07-14 08:51:46","TRTEDTM":"2022-07-14 02:51:46","TRT01SDTM":"2019-07-14 08:51:46","TRT01EDTM":"2021-07-13 20:51:46","TRT02SDTM":"2021-07-13 20:51:46","TRT02EDTM":"2022-07-14 02:51:46","AP01SDTM":"2019-07-14 08:51:46","AP01EDTM":"2021-07-13 20:51:46","AP02SDTM":"2021-07-13 20:51:46","AP02EDTM":"2022-07-14 02:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-14","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4758,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89911,"AVALU":"g/L","BASE2":2.93726,"BASE":2.77494,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03815,"PCHG2":-1.29883,"CHG":0.12417,"PCHG":4.47476,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-21 08:51:46","ADY":526,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-124","SUBJID":"id-124","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36798,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-12","TRTSDTM":"2019-07-14 08:51:46","TRTEDTM":"2022-07-14 02:51:46","TRT01SDTM":"2019-07-14 08:51:46","TRT01EDTM":"2021-07-13 20:51:46","TRT02SDTM":"2021-07-13 20:51:46","TRT02EDTM":"2022-07-14 02:51:46","AP01SDTM":"2019-07-14 08:51:46","AP01EDTM":"2021-07-13 20:51:46","AP02SDTM":"2021-07-13 20:51:46","AP02EDTM":"2022-07-14 02:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-14","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3970,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89673,"AVALU":"g/L","BASE2":2.93726,"BASE":2.77494,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04053,"PCHG2":-1.37982,"CHG":0.12179,"PCHG":4.38903,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-23 08:51:46","ADY":590,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-124","SUBJID":"id-124","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36798,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-12","TRTSDTM":"2019-07-14 08:51:46","TRTEDTM":"2022-07-14 02:51:46","TRT01SDTM":"2019-07-14 08:51:46","TRT01EDTM":"2021-07-13 20:51:46","TRT02SDTM":"2021-07-13 20:51:46","TRT02EDTM":"2022-07-14 02:51:46","AP01SDTM":"2019-07-14 08:51:46","AP01EDTM":"2021-07-13 20:51:46","AP02SDTM":"2021-07-13 20:51:46","AP02EDTM":"2022-07-14 02:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-14","EOSDY":1096,"LSTALVDT":"2022-08-11","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2406,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02823,"AVALU":"g/L","BASE2":2.93726,"BASE":2.77494,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09097,"PCHG2":3.097,"CHG":0.25329,"PCHG":9.12772,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2022-02-12 08:51:46","ADY":944,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-132","SUBJID":"id-132","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.94925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-27 13:22:51","TRTEDTM":"2022-02-18 18:49:35","TRT01SDTM":"2020-02-27 13:22:51","TRT01EDTM":"2021-02-18 12:49:35","TRT02SDTM":"2021-02-18 12:49:35","TRT02EDTM":"2022-02-18 18:49:35","AP01SDTM":"2020-02-27 13:22:51","AP01EDTM":"2021-02-18 12:49:35","AP02SDTM":"2021-02-18 12:49:35","AP02EDTM":"2022-02-18 18:49:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":723,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-19","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":117,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.41327,"AVALU":"U/L","BASE2":23.41327,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-03-09 13:22:51","ADY":11,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-132","SUBJID":"id-132","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.94925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-27 13:22:51","TRTEDTM":"2022-02-18 18:49:35","TRT01SDTM":"2020-02-27 13:22:51","TRT01EDTM":"2021-02-18 12:49:35","TRT02SDTM":"2021-02-18 12:49:35","TRT02EDTM":"2022-02-18 18:49:35","AP01SDTM":"2020-02-27 13:22:51","AP01EDTM":"2021-02-18 12:49:35","AP02SDTM":"2021-02-18 12:49:35","AP02EDTM":"2022-02-18 18:49:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":723,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-19","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1694,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.32316,"AVALU":"U/L","BASE2":23.41327,"BASE":3.32316,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-20.09012,"PCHG2":-85.80653,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2020-03-21 13:22:51","ADY":23,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-132","SUBJID":"id-132","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.94925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-27 13:22:51","TRTEDTM":"2022-02-18 18:49:35","TRT01SDTM":"2020-02-27 13:22:51","TRT01EDTM":"2021-02-18 12:49:35","TRT02SDTM":"2021-02-18 12:49:35","TRT02EDTM":"2022-02-18 18:49:35","AP01SDTM":"2020-02-27 13:22:51","AP01EDTM":"2021-02-18 12:49:35","AP02SDTM":"2021-02-18 12:49:35","AP02EDTM":"2022-02-18 18:49:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":723,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-19","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5363,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.96873,"AVALU":"U/L","BASE2":23.41327,"BASE":3.32316,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.44454,"PCHG2":-40.3384,"CHG":10.64558,"PCHG":320.34535,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-03-26 13:22:51","ADY":28,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-132","SUBJID":"id-132","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.94925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-27 13:22:51","TRTEDTM":"2022-02-18 18:49:35","TRT01SDTM":"2020-02-27 13:22:51","TRT01EDTM":"2021-02-18 12:49:35","TRT02SDTM":"2021-02-18 12:49:35","TRT02EDTM":"2022-02-18 18:49:35","AP01SDTM":"2020-02-27 13:22:51","AP01EDTM":"2021-02-18 12:49:35","AP02SDTM":"2021-02-18 12:49:35","AP02EDTM":"2022-02-18 18:49:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":723,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-19","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":50,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.76386,"AVALU":"U/L","BASE2":23.41327,"BASE":3.32316,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.64941,"PCHG2":-58.29774,"CHG":6.44071,"PCHG":193.81294,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-06-18 13:22:51","ADY":112,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-132","SUBJID":"id-132","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.94925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-27 13:22:51","TRTEDTM":"2022-02-18 18:49:35","TRT01SDTM":"2020-02-27 13:22:51","TRT01EDTM":"2021-02-18 12:49:35","TRT02SDTM":"2021-02-18 12:49:35","TRT02EDTM":"2022-02-18 18:49:35","AP01SDTM":"2020-02-27 13:22:51","AP01EDTM":"2021-02-18 12:49:35","AP02SDTM":"2021-02-18 12:49:35","AP02EDTM":"2022-02-18 18:49:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":723,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-19","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7373,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.97791,"AVALU":"U/L","BASE2":23.41327,"BASE":3.32316,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.56464,"PCHG2":2.41161,"CHG":20.65475,"PCHG":621.5402,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-10-17 13:22:51","ADY":233,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-132","SUBJID":"id-132","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.94925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-27 13:22:51","TRTEDTM":"2022-02-18 18:49:35","TRT01SDTM":"2020-02-27 13:22:51","TRT01EDTM":"2021-02-18 12:49:35","TRT02SDTM":"2021-02-18 12:49:35","TRT02EDTM":"2022-02-18 18:49:35","AP01SDTM":"2020-02-27 13:22:51","AP01EDTM":"2021-02-18 12:49:35","AP02SDTM":"2021-02-18 12:49:35","AP02EDTM":"2022-02-18 18:49:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":723,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-19","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":392,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.36812,"AVALU":"U/L","BASE2":23.41327,"BASE":3.32316,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.04515,"PCHG2":-30.09043,"CHG":13.04496,"PCHG":392.54735,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-02-08 13:22:51","ADY":347,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-132","SUBJID":"id-132","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.94925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-27 13:22:51","TRTEDTM":"2022-02-18 18:49:35","TRT01SDTM":"2020-02-27 13:22:51","TRT01EDTM":"2021-02-18 12:49:35","TRT02SDTM":"2021-02-18 12:49:35","TRT02EDTM":"2022-02-18 18:49:35","AP01SDTM":"2020-02-27 13:22:51","AP01EDTM":"2021-02-18 12:49:35","AP02SDTM":"2021-02-18 12:49:35","AP02EDTM":"2022-02-18 18:49:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":723,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-19","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5990,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.39062,"AVALU":"U/L","BASE2":23.41327,"BASE":3.32316,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.97735,"PCHG2":42.61407,"CHG":30.06747,"PCHG":904.78636,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-08-30 13:22:51","ADY":550,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-132","SUBJID":"id-132","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.94925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-27 13:22:51","TRTEDTM":"2022-02-18 18:49:35","TRT01SDTM":"2020-02-27 13:22:51","TRT01EDTM":"2021-02-18 12:49:35","TRT02SDTM":"2021-02-18 12:49:35","TRT02EDTM":"2022-02-18 18:49:35","AP01SDTM":"2020-02-27 13:22:51","AP01EDTM":"2021-02-18 12:49:35","AP02SDTM":"2021-02-18 12:49:35","AP02EDTM":"2022-02-18 18:49:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":723,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-19","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1041,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.41542,"AVALU":"mg/L","BASE2":10.41542,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-03-09 13:22:51","ADY":11,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-132","SUBJID":"id-132","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.94925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-27 13:22:51","TRTEDTM":"2022-02-18 18:49:35","TRT01SDTM":"2020-02-27 13:22:51","TRT01EDTM":"2021-02-18 12:49:35","TRT02SDTM":"2021-02-18 12:49:35","TRT02EDTM":"2022-02-18 18:49:35","AP01SDTM":"2020-02-27 13:22:51","AP01EDTM":"2021-02-18 12:49:35","AP02SDTM":"2021-02-18 12:49:35","AP02EDTM":"2022-02-18 18:49:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":723,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-19","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":585,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.04031,"AVALU":"mg/L","BASE2":10.41542,"BASE":9.04031,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.37511,"PCHG2":-13.20262,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-21 13:22:51","ADY":23,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-132","SUBJID":"id-132","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.94925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-27 13:22:51","TRTEDTM":"2022-02-18 18:49:35","TRT01SDTM":"2020-02-27 13:22:51","TRT01EDTM":"2021-02-18 12:49:35","TRT02SDTM":"2021-02-18 12:49:35","TRT02EDTM":"2022-02-18 18:49:35","AP01SDTM":"2020-02-27 13:22:51","AP01EDTM":"2021-02-18 12:49:35","AP02SDTM":"2021-02-18 12:49:35","AP02EDTM":"2022-02-18 18:49:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":723,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-19","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5371,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.53909,"AVALU":"mg/L","BASE2":10.41542,"BASE":9.04031,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.87633,"PCHG2":-8.41376,"CHG":0.49878,"PCHG":5.51729,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-26 13:22:51","ADY":28,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-132","SUBJID":"id-132","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.94925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-27 13:22:51","TRTEDTM":"2022-02-18 18:49:35","TRT01SDTM":"2020-02-27 13:22:51","TRT01EDTM":"2021-02-18 12:49:35","TRT02SDTM":"2021-02-18 12:49:35","TRT02EDTM":"2022-02-18 18:49:35","AP01SDTM":"2020-02-27 13:22:51","AP01EDTM":"2021-02-18 12:49:35","AP02SDTM":"2021-02-18 12:49:35","AP02EDTM":"2022-02-18 18:49:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":723,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-19","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8023,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.38048,"AVALU":"mg/L","BASE2":10.41542,"BASE":9.04031,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.03493,"PCHG2":-19.53772,"CHG":-0.65983,"PCHG":-7.29872,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-18 13:22:51","ADY":112,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-132","SUBJID":"id-132","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.94925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-27 13:22:51","TRTEDTM":"2022-02-18 18:49:35","TRT01SDTM":"2020-02-27 13:22:51","TRT01EDTM":"2021-02-18 12:49:35","TRT02SDTM":"2021-02-18 12:49:35","TRT02EDTM":"2022-02-18 18:49:35","AP01SDTM":"2020-02-27 13:22:51","AP01EDTM":"2021-02-18 12:49:35","AP02SDTM":"2021-02-18 12:49:35","AP02EDTM":"2022-02-18 18:49:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":723,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-19","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7528,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.81091,"AVALU":"mg/L","BASE2":10.41542,"BASE":9.04031,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.60451,"PCHG2":-5.80401,"CHG":0.7706,"PCHG":8.524,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-17 13:22:51","ADY":233,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-132","SUBJID":"id-132","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.94925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-27 13:22:51","TRTEDTM":"2022-02-18 18:49:35","TRT01SDTM":"2020-02-27 13:22:51","TRT01EDTM":"2021-02-18 12:49:35","TRT02SDTM":"2021-02-18 12:49:35","TRT02EDTM":"2022-02-18 18:49:35","AP01SDTM":"2020-02-27 13:22:51","AP01EDTM":"2021-02-18 12:49:35","AP02SDTM":"2021-02-18 12:49:35","AP02EDTM":"2022-02-18 18:49:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":723,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-19","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5395,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.60589,"AVALU":"mg/L","BASE2":10.41542,"BASE":9.04031,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.80952,"PCHG2":-26.97467,"CHG":-1.43442,"PCHG":-15.86689,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-02-08 13:22:51","ADY":347,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-132","SUBJID":"id-132","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.94925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-27 13:22:51","TRTEDTM":"2022-02-18 18:49:35","TRT01SDTM":"2020-02-27 13:22:51","TRT01EDTM":"2021-02-18 12:49:35","TRT02SDTM":"2021-02-18 12:49:35","TRT02EDTM":"2022-02-18 18:49:35","AP01SDTM":"2020-02-27 13:22:51","AP01EDTM":"2021-02-18 12:49:35","AP02SDTM":"2021-02-18 12:49:35","AP02EDTM":"2022-02-18 18:49:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":723,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-19","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1518,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.7044,"AVALU":"mg/L","BASE2":10.41542,"BASE":9.04031,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.71102,"PCHG2":-6.82662,"CHG":0.66409,"PCHG":7.34584,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-30 13:22:51","ADY":550,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-132","SUBJID":"id-132","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.94925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-27 13:22:51","TRTEDTM":"2022-02-18 18:49:35","TRT01SDTM":"2020-02-27 13:22:51","TRT01EDTM":"2021-02-18 12:49:35","TRT02SDTM":"2021-02-18 12:49:35","TRT02EDTM":"2022-02-18 18:49:35","AP01SDTM":"2020-02-27 13:22:51","AP01EDTM":"2021-02-18 12:49:35","AP02SDTM":"2021-02-18 12:49:35","AP02EDTM":"2022-02-18 18:49:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":723,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-19","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4585,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0287,"AVALU":"g/L","BASE2":3.0287,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-03-09 13:22:51","ADY":11,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-132","SUBJID":"id-132","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.94925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-27 13:22:51","TRTEDTM":"2022-02-18 18:49:35","TRT01SDTM":"2020-02-27 13:22:51","TRT01EDTM":"2021-02-18 12:49:35","TRT02SDTM":"2021-02-18 12:49:35","TRT02EDTM":"2022-02-18 18:49:35","AP01SDTM":"2020-02-27 13:22:51","AP01EDTM":"2021-02-18 12:49:35","AP02SDTM":"2021-02-18 12:49:35","AP02EDTM":"2022-02-18 18:49:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":723,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-19","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1369,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.72979,"AVALU":"g/L","BASE2":3.0287,"BASE":2.72979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.29891,"PCHG2":-9.86938,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-21 13:22:51","ADY":23,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-132","SUBJID":"id-132","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.94925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-27 13:22:51","TRTEDTM":"2022-02-18 18:49:35","TRT01SDTM":"2020-02-27 13:22:51","TRT01EDTM":"2021-02-18 12:49:35","TRT02SDTM":"2021-02-18 12:49:35","TRT02EDTM":"2022-02-18 18:49:35","AP01SDTM":"2020-02-27 13:22:51","AP01EDTM":"2021-02-18 12:49:35","AP02SDTM":"2021-02-18 12:49:35","AP02EDTM":"2022-02-18 18:49:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":723,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-19","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1693,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98414,"AVALU":"g/L","BASE2":3.0287,"BASE":2.72979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04456,"PCHG2":-1.4714,"CHG":0.25435,"PCHG":9.31757,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-26 13:22:51","ADY":28,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-132","SUBJID":"id-132","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.94925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-27 13:22:51","TRTEDTM":"2022-02-18 18:49:35","TRT01SDTM":"2020-02-27 13:22:51","TRT01EDTM":"2021-02-18 12:49:35","TRT02SDTM":"2021-02-18 12:49:35","TRT02EDTM":"2022-02-18 18:49:35","AP01SDTM":"2020-02-27 13:22:51","AP01EDTM":"2021-02-18 12:49:35","AP02SDTM":"2021-02-18 12:49:35","AP02EDTM":"2022-02-18 18:49:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":723,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-19","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8314,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77163,"AVALU":"g/L","BASE2":3.0287,"BASE":2.72979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.25707,"PCHG2":-8.48787,"CHG":0.04184,"PCHG":1.53279,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-18 13:22:51","ADY":112,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-132","SUBJID":"id-132","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.94925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-27 13:22:51","TRTEDTM":"2022-02-18 18:49:35","TRT01SDTM":"2020-02-27 13:22:51","TRT01EDTM":"2021-02-18 12:49:35","TRT02SDTM":"2021-02-18 12:49:35","TRT02EDTM":"2022-02-18 18:49:35","AP01SDTM":"2020-02-27 13:22:51","AP01EDTM":"2021-02-18 12:49:35","AP02SDTM":"2021-02-18 12:49:35","AP02EDTM":"2022-02-18 18:49:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":723,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-19","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":603,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98082,"AVALU":"g/L","BASE2":3.0287,"BASE":2.72979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04788,"PCHG2":-1.58096,"CHG":0.25103,"PCHG":9.19601,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-17 13:22:51","ADY":233,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-132","SUBJID":"id-132","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.94925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-27 13:22:51","TRTEDTM":"2022-02-18 18:49:35","TRT01SDTM":"2020-02-27 13:22:51","TRT01EDTM":"2021-02-18 12:49:35","TRT02SDTM":"2021-02-18 12:49:35","TRT02EDTM":"2022-02-18 18:49:35","AP01SDTM":"2020-02-27 13:22:51","AP01EDTM":"2021-02-18 12:49:35","AP02SDTM":"2021-02-18 12:49:35","AP02EDTM":"2022-02-18 18:49:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":723,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-19","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1216,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03436,"AVALU":"g/L","BASE2":3.0287,"BASE":2.72979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00566,"PCHG2":0.18675,"CHG":0.30457,"PCHG":11.15729,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-02-08 13:22:51","ADY":347,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-132","SUBJID":"id-132","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.94925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-25","TRTSDTM":"2020-02-27 13:22:51","TRTEDTM":"2022-02-18 18:49:35","TRT01SDTM":"2020-02-27 13:22:51","TRT01EDTM":"2021-02-18 12:49:35","TRT02SDTM":"2021-02-18 12:49:35","TRT02EDTM":"2022-02-18 18:49:35","AP01SDTM":"2020-02-27 13:22:51","AP01EDTM":"2021-02-18 12:49:35","AP02SDTM":"2021-02-18 12:49:35","AP02EDTM":"2022-02-18 18:49:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":723,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-19","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":422,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96106,"AVALU":"g/L","BASE2":3.0287,"BASE":2.72979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06764,"PCHG2":-2.23334,"CHG":0.23127,"PCHG":8.47219,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-30 13:22:51","ADY":550,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-146","SUBJID":"id-146","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.15901,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-05","TRTSDTM":"2021-01-09 20:42:25","TRTEDTM":"2024-01-10 14:42:25","TRT01SDTM":"2021-01-09 20:42:25","TRT01EDTM":"2023-01-10 08:42:25","TRT02SDTM":"2023-01-10 08:42:25","TRT02EDTM":"2024-01-10 14:42:25","AP01SDTM":"2021-01-09 20:42:25","AP01EDTM":"2023-01-10 08:42:25","AP02SDTM":"2023-01-10 08:42:25","AP02EDTM":"2024-01-10 14:42:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-10","EOSDY":1096,"LSTALVDT":"2024-02-07","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8180,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.62587,"AVALU":"U/L","BASE2":25.62587,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-02-12 20:42:25","ADY":34,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-146","SUBJID":"id-146","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.15901,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-05","TRTSDTM":"2021-01-09 20:42:25","TRTEDTM":"2024-01-10 14:42:25","TRT01SDTM":"2021-01-09 20:42:25","TRT01EDTM":"2023-01-10 08:42:25","TRT02SDTM":"2023-01-10 08:42:25","TRT02EDTM":"2024-01-10 14:42:25","AP01SDTM":"2021-01-09 20:42:25","AP01EDTM":"2023-01-10 08:42:25","AP02SDTM":"2023-01-10 08:42:25","AP02EDTM":"2024-01-10 14:42:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-10","EOSDY":1096,"LSTALVDT":"2024-02-07","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6896,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.53293,"AVALU":"U/L","BASE2":25.62587,"BASE":4.53293,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-21.09294,"PCHG2":-82.31112,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2021-06-05 20:42:25","ADY":147,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-146","SUBJID":"id-146","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.15901,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-05","TRTSDTM":"2021-01-09 20:42:25","TRTEDTM":"2024-01-10 14:42:25","TRT01SDTM":"2021-01-09 20:42:25","TRT01EDTM":"2023-01-10 08:42:25","TRT02SDTM":"2023-01-10 08:42:25","TRT02EDTM":"2024-01-10 14:42:25","AP01SDTM":"2021-01-09 20:42:25","AP01EDTM":"2023-01-10 08:42:25","AP02SDTM":"2023-01-10 08:42:25","AP02EDTM":"2024-01-10 14:42:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-10","EOSDY":1096,"LSTALVDT":"2024-02-07","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1405,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.18283,"AVALU":"U/L","BASE2":25.62587,"BASE":4.53293,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.44304,"PCHG2":-21.2404,"CHG":15.6499,"PCHG":345.24928,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-12-26 20:42:25","ADY":351,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-146","SUBJID":"id-146","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.15901,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-05","TRTSDTM":"2021-01-09 20:42:25","TRTEDTM":"2024-01-10 14:42:25","TRT01SDTM":"2021-01-09 20:42:25","TRT01EDTM":"2023-01-10 08:42:25","TRT02SDTM":"2023-01-10 08:42:25","TRT02EDTM":"2024-01-10 14:42:25","AP01SDTM":"2021-01-09 20:42:25","AP01EDTM":"2023-01-10 08:42:25","AP02SDTM":"2023-01-10 08:42:25","AP02EDTM":"2024-01-10 14:42:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-10","EOSDY":1096,"LSTALVDT":"2024-02-07","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3136,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.74337,"AVALU":"U/L","BASE2":25.62587,"BASE":4.53293,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.8825,"PCHG2":-7.34607,"CHG":19.21044,"PCHG":423.79763,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-08-17 20:42:25","ADY":585,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-146","SUBJID":"id-146","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.15901,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-05","TRTSDTM":"2021-01-09 20:42:25","TRTEDTM":"2024-01-10 14:42:25","TRT01SDTM":"2021-01-09 20:42:25","TRT01EDTM":"2023-01-10 08:42:25","TRT02SDTM":"2023-01-10 08:42:25","TRT02EDTM":"2024-01-10 14:42:25","AP01SDTM":"2021-01-09 20:42:25","AP01EDTM":"2023-01-10 08:42:25","AP02SDTM":"2023-01-10 08:42:25","AP02EDTM":"2024-01-10 14:42:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-10","EOSDY":1096,"LSTALVDT":"2024-02-07","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7773,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.42456,"AVALU":"U/L","BASE2":25.62587,"BASE":4.53293,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.20131,"PCHG2":-51.51557,"CHG":7.89163,"PCHG":174.09558,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-09-17 20:42:25","ADY":616,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-146","SUBJID":"id-146","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.15901,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-05","TRTSDTM":"2021-01-09 20:42:25","TRTEDTM":"2024-01-10 14:42:25","TRT01SDTM":"2021-01-09 20:42:25","TRT01EDTM":"2023-01-10 08:42:25","TRT02SDTM":"2023-01-10 08:42:25","TRT02EDTM":"2024-01-10 14:42:25","AP01SDTM":"2021-01-09 20:42:25","AP01EDTM":"2023-01-10 08:42:25","AP02SDTM":"2023-01-10 08:42:25","AP02EDTM":"2024-01-10 14:42:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-10","EOSDY":1096,"LSTALVDT":"2024-02-07","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8032,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.46712,"AVALU":"U/L","BASE2":25.62587,"BASE":4.53293,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.15874,"PCHG2":-51.34946,"CHG":7.93419,"PCHG":175.03465,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2023-07-08 20:42:25","ADY":910,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-146","SUBJID":"id-146","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.15901,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-05","TRTSDTM":"2021-01-09 20:42:25","TRTEDTM":"2024-01-10 14:42:25","TRT01SDTM":"2021-01-09 20:42:25","TRT01EDTM":"2023-01-10 08:42:25","TRT02SDTM":"2023-01-10 08:42:25","TRT02EDTM":"2024-01-10 14:42:25","AP01SDTM":"2021-01-09 20:42:25","AP01EDTM":"2023-01-10 08:42:25","AP02SDTM":"2023-01-10 08:42:25","AP02EDTM":"2024-01-10 14:42:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-10","EOSDY":1096,"LSTALVDT":"2024-02-07","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6328,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.73924,"AVALU":"U/L","BASE2":25.62587,"BASE":4.53293,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.11337,"PCHG2":4.34472,"CHG":22.20631,"PCHG":489.88885,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2023-11-20 20:42:25","ADY":1045,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-146","SUBJID":"id-146","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.15901,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-05","TRTSDTM":"2021-01-09 20:42:25","TRTEDTM":"2024-01-10 14:42:25","TRT01SDTM":"2021-01-09 20:42:25","TRT01EDTM":"2023-01-10 08:42:25","TRT02SDTM":"2023-01-10 08:42:25","TRT02EDTM":"2024-01-10 14:42:25","AP01SDTM":"2021-01-09 20:42:25","AP01EDTM":"2023-01-10 08:42:25","AP02SDTM":"2023-01-10 08:42:25","AP02EDTM":"2024-01-10 14:42:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-10","EOSDY":1096,"LSTALVDT":"2024-02-07","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3589,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.67828,"AVALU":"mg/L","BASE2":9.67828,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-02-12 20:42:25","ADY":34,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-146","SUBJID":"id-146","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.15901,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-05","TRTSDTM":"2021-01-09 20:42:25","TRTEDTM":"2024-01-10 14:42:25","TRT01SDTM":"2021-01-09 20:42:25","TRT01EDTM":"2023-01-10 08:42:25","TRT02SDTM":"2023-01-10 08:42:25","TRT02EDTM":"2024-01-10 14:42:25","AP01SDTM":"2021-01-09 20:42:25","AP01EDTM":"2023-01-10 08:42:25","AP02SDTM":"2023-01-10 08:42:25","AP02EDTM":"2024-01-10 14:42:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-10","EOSDY":1096,"LSTALVDT":"2024-02-07","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1396,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.42885,"AVALU":"mg/L","BASE2":9.67828,"BASE":7.42885,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.24944,"PCHG2":-23.2421,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-4","BTOXGR":"-4","ADTM":"2021-06-05 20:42:25","ADY":147,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-146","SUBJID":"id-146","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.15901,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-05","TRTSDTM":"2021-01-09 20:42:25","TRTEDTM":"2024-01-10 14:42:25","TRT01SDTM":"2021-01-09 20:42:25","TRT01EDTM":"2023-01-10 08:42:25","TRT02SDTM":"2023-01-10 08:42:25","TRT02EDTM":"2024-01-10 14:42:25","AP01SDTM":"2021-01-09 20:42:25","AP01EDTM":"2023-01-10 08:42:25","AP02SDTM":"2023-01-10 08:42:25","AP02EDTM":"2024-01-10 14:42:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-10","EOSDY":1096,"LSTALVDT":"2024-02-07","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6247,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.18213,"AVALU":"mg/L","BASE2":9.67828,"BASE":7.42885,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.49615,"PCHG2":-5.12644,"CHG":1.75328,"PCHG":23.60103,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-12-26 20:42:25","ADY":351,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-146","SUBJID":"id-146","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.15901,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-05","TRTSDTM":"2021-01-09 20:42:25","TRTEDTM":"2024-01-10 14:42:25","TRT01SDTM":"2021-01-09 20:42:25","TRT01EDTM":"2023-01-10 08:42:25","TRT02SDTM":"2023-01-10 08:42:25","TRT02EDTM":"2024-01-10 14:42:25","AP01SDTM":"2021-01-09 20:42:25","AP01EDTM":"2023-01-10 08:42:25","AP02SDTM":"2023-01-10 08:42:25","AP02EDTM":"2024-01-10 14:42:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-10","EOSDY":1096,"LSTALVDT":"2024-02-07","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4007,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.88681,"AVALU":"mg/L","BASE2":9.67828,"BASE":7.42885,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.79148,"PCHG2":-18.51026,"CHG":0.45796,"PCHG":6.16462,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-3","BTOXGR":"-4","ADTM":"2022-08-17 20:42:25","ADY":585,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-146","SUBJID":"id-146","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.15901,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-05","TRTSDTM":"2021-01-09 20:42:25","TRTEDTM":"2024-01-10 14:42:25","TRT01SDTM":"2021-01-09 20:42:25","TRT01EDTM":"2023-01-10 08:42:25","TRT02SDTM":"2023-01-10 08:42:25","TRT02EDTM":"2024-01-10 14:42:25","AP01SDTM":"2021-01-09 20:42:25","AP01EDTM":"2023-01-10 08:42:25","AP02SDTM":"2023-01-10 08:42:25","AP02EDTM":"2024-01-10 14:42:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-10","EOSDY":1096,"LSTALVDT":"2024-02-07","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8233,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.4789,"AVALU":"mg/L","BASE2":9.67828,"BASE":7.42885,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.19939,"PCHG2":-12.39254,"CHG":1.05005,"PCHG":14.13477,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2022-09-17 20:42:25","ADY":616,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-146","SUBJID":"id-146","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.15901,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-05","TRTSDTM":"2021-01-09 20:42:25","TRTEDTM":"2024-01-10 14:42:25","TRT01SDTM":"2021-01-09 20:42:25","TRT01EDTM":"2023-01-10 08:42:25","TRT02SDTM":"2023-01-10 08:42:25","TRT02EDTM":"2024-01-10 14:42:25","AP01SDTM":"2021-01-09 20:42:25","AP01EDTM":"2023-01-10 08:42:25","AP02SDTM":"2023-01-10 08:42:25","AP02EDTM":"2024-01-10 14:42:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-10","EOSDY":1096,"LSTALVDT":"2024-02-07","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3187,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.20588,"AVALU":"mg/L","BASE2":9.67828,"BASE":7.42885,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.47241,"PCHG2":-15.21353,"CHG":0.77703,"PCHG":10.45959,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2023-07-08 20:42:25","ADY":910,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-146","SUBJID":"id-146","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.15901,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-05","TRTSDTM":"2021-01-09 20:42:25","TRTEDTM":"2024-01-10 14:42:25","TRT01SDTM":"2021-01-09 20:42:25","TRT01EDTM":"2023-01-10 08:42:25","TRT02SDTM":"2023-01-10 08:42:25","TRT02EDTM":"2024-01-10 14:42:25","AP01SDTM":"2021-01-09 20:42:25","AP01EDTM":"2023-01-10 08:42:25","AP02SDTM":"2023-01-10 08:42:25","AP02EDTM":"2024-01-10 14:42:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-10","EOSDY":1096,"LSTALVDT":"2024-02-07","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3884,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.62194,"AVALU":"mg/L","BASE2":9.67828,"BASE":7.42885,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05634,"PCHG2":-0.58217,"CHG":2.19309,"PCHG":29.52129,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2023-11-20 20:42:25","ADY":1045,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-146","SUBJID":"id-146","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.15901,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-05","TRTSDTM":"2021-01-09 20:42:25","TRTEDTM":"2024-01-10 14:42:25","TRT01SDTM":"2021-01-09 20:42:25","TRT01EDTM":"2023-01-10 08:42:25","TRT02SDTM":"2023-01-10 08:42:25","TRT02EDTM":"2024-01-10 14:42:25","AP01SDTM":"2021-01-09 20:42:25","AP01EDTM":"2023-01-10 08:42:25","AP02SDTM":"2023-01-10 08:42:25","AP02EDTM":"2024-01-10 14:42:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-10","EOSDY":1096,"LSTALVDT":"2024-02-07","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6295,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.72134,"AVALU":"g/L","BASE2":2.72134,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-12 20:42:25","ADY":34,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-146","SUBJID":"id-146","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.15901,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-05","TRTSDTM":"2021-01-09 20:42:25","TRTEDTM":"2024-01-10 14:42:25","TRT01SDTM":"2021-01-09 20:42:25","TRT01EDTM":"2023-01-10 08:42:25","TRT02SDTM":"2023-01-10 08:42:25","TRT02EDTM":"2024-01-10 14:42:25","AP01SDTM":"2021-01-09 20:42:25","AP01EDTM":"2023-01-10 08:42:25","AP02SDTM":"2023-01-10 08:42:25","AP02EDTM":"2024-01-10 14:42:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-10","EOSDY":1096,"LSTALVDT":"2024-02-07","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":442,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88078,"AVALU":"g/L","BASE2":2.72134,"BASE":2.88078,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.15944,"PCHG2":5.85886,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-05 20:42:25","ADY":147,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-146","SUBJID":"id-146","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.15901,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-05","TRTSDTM":"2021-01-09 20:42:25","TRTEDTM":"2024-01-10 14:42:25","TRT01SDTM":"2021-01-09 20:42:25","TRT01EDTM":"2023-01-10 08:42:25","TRT02SDTM":"2023-01-10 08:42:25","TRT02EDTM":"2024-01-10 14:42:25","AP01SDTM":"2021-01-09 20:42:25","AP01EDTM":"2023-01-10 08:42:25","AP02SDTM":"2023-01-10 08:42:25","AP02EDTM":"2024-01-10 14:42:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-10","EOSDY":1096,"LSTALVDT":"2024-02-07","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6947,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.08815,"AVALU":"g/L","BASE2":2.72134,"BASE":2.88078,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.36681,"PCHG2":13.47899,"CHG":0.20737,"PCHG":7.19838,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-12-26 20:42:25","ADY":351,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-146","SUBJID":"id-146","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.15901,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-05","TRTSDTM":"2021-01-09 20:42:25","TRTEDTM":"2024-01-10 14:42:25","TRT01SDTM":"2021-01-09 20:42:25","TRT01EDTM":"2023-01-10 08:42:25","TRT02SDTM":"2023-01-10 08:42:25","TRT02EDTM":"2024-01-10 14:42:25","AP01SDTM":"2021-01-09 20:42:25","AP01EDTM":"2023-01-10 08:42:25","AP02SDTM":"2023-01-10 08:42:25","AP02EDTM":"2024-01-10 14:42:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-10","EOSDY":1096,"LSTALVDT":"2024-02-07","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1311,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84799,"AVALU":"g/L","BASE2":2.72134,"BASE":2.88078,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12665,"PCHG2":4.65384,"CHG":-0.03279,"PCHG":-1.13833,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-17 20:42:25","ADY":585,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-146","SUBJID":"id-146","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.15901,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-05","TRTSDTM":"2021-01-09 20:42:25","TRTEDTM":"2024-01-10 14:42:25","TRT01SDTM":"2021-01-09 20:42:25","TRT01EDTM":"2023-01-10 08:42:25","TRT02SDTM":"2023-01-10 08:42:25","TRT02EDTM":"2024-01-10 14:42:25","AP01SDTM":"2021-01-09 20:42:25","AP01EDTM":"2023-01-10 08:42:25","AP02SDTM":"2023-01-10 08:42:25","AP02EDTM":"2024-01-10 14:42:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-10","EOSDY":1096,"LSTALVDT":"2024-02-07","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1296,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.15809,"AVALU":"g/L","BASE2":2.72134,"BASE":2.88078,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.43675,"PCHG2":16.04892,"CHG":0.27731,"PCHG":9.62608,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-09-17 20:42:25","ADY":616,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-146","SUBJID":"id-146","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.15901,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-05","TRTSDTM":"2021-01-09 20:42:25","TRTEDTM":"2024-01-10 14:42:25","TRT01SDTM":"2021-01-09 20:42:25","TRT01EDTM":"2023-01-10 08:42:25","TRT02SDTM":"2023-01-10 08:42:25","TRT02EDTM":"2024-01-10 14:42:25","AP01SDTM":"2021-01-09 20:42:25","AP01EDTM":"2023-01-10 08:42:25","AP02SDTM":"2023-01-10 08:42:25","AP02EDTM":"2024-01-10 14:42:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-10","EOSDY":1096,"LSTALVDT":"2024-02-07","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3053,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88579,"AVALU":"g/L","BASE2":2.72134,"BASE":2.88078,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16445,"PCHG2":6.04297,"CHG":0.00501,"PCHG":0.17392,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-08 20:42:25","ADY":910,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-146","SUBJID":"id-146","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.15901,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-05","TRTSDTM":"2021-01-09 20:42:25","TRTEDTM":"2024-01-10 14:42:25","TRT01SDTM":"2021-01-09 20:42:25","TRT01EDTM":"2023-01-10 08:42:25","TRT02SDTM":"2023-01-10 08:42:25","TRT02EDTM":"2024-01-10 14:42:25","AP01SDTM":"2021-01-09 20:42:25","AP01EDTM":"2023-01-10 08:42:25","AP02SDTM":"2023-01-10 08:42:25","AP02EDTM":"2024-01-10 14:42:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-10","EOSDY":1096,"LSTALVDT":"2024-02-07","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4757,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87751,"AVALU":"g/L","BASE2":2.72134,"BASE":2.88078,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15617,"PCHG2":5.7387,"CHG":-0.00327,"PCHG":-0.11351,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-11-20 20:42:25","ADY":1045,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-153","SUBJID":"id-153","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.79286,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 21:15:26","TRTEDTM":"2023-10-14 15:15:26","TRT01SDTM":"2020-10-13 21:15:26","TRT01EDTM":"2022-10-14 09:15:26","TRT02SDTM":"2022-10-14 09:15:26","TRT02EDTM":"2023-10-14 15:15:26","AP01SDTM":"2020-10-13 21:15:26","AP01EDTM":"2022-10-14 09:15:26","AP02SDTM":"2022-10-14 09:15:26","AP02EDTM":"2023-10-14 15:15:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-14","EOSDY":1096,"LSTALVDT":"2023-11-02","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6146,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.72899,"AVALU":"U/L","BASE2":14.72899,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-24 21:15:26","ADY":72,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-153","SUBJID":"id-153","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.79286,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 21:15:26","TRTEDTM":"2023-10-14 15:15:26","TRT01SDTM":"2020-10-13 21:15:26","TRT01EDTM":"2022-10-14 09:15:26","TRT02SDTM":"2022-10-14 09:15:26","TRT02EDTM":"2023-10-14 15:15:26","AP01SDTM":"2020-10-13 21:15:26","AP01EDTM":"2022-10-14 09:15:26","AP02SDTM":"2022-10-14 09:15:26","AP02EDTM":"2023-10-14 15:15:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-14","EOSDY":1096,"LSTALVDT":"2023-11-02","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7977,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.22055,"AVALU":"U/L","BASE2":14.72899,"BASE":19.22055,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":4.49156,"PCHG2":30.49468,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-29 21:15:26","ADY":77,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-153","SUBJID":"id-153","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.79286,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 21:15:26","TRTEDTM":"2023-10-14 15:15:26","TRT01SDTM":"2020-10-13 21:15:26","TRT01EDTM":"2022-10-14 09:15:26","TRT02SDTM":"2022-10-14 09:15:26","TRT02EDTM":"2023-10-14 15:15:26","AP01SDTM":"2020-10-13 21:15:26","AP01EDTM":"2022-10-14 09:15:26","AP02SDTM":"2022-10-14 09:15:26","AP02EDTM":"2023-10-14 15:15:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-14","EOSDY":1096,"LSTALVDT":"2023-11-02","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7411,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.3125,"AVALU":"U/L","BASE2":14.72899,"BASE":19.22055,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.58351,"PCHG2":37.90831,"CHG":1.09195,"PCHG":5.68117,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-10 21:15:26","ADY":240,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-153","SUBJID":"id-153","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.79286,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 21:15:26","TRTEDTM":"2023-10-14 15:15:26","TRT01SDTM":"2020-10-13 21:15:26","TRT01EDTM":"2022-10-14 09:15:26","TRT02SDTM":"2022-10-14 09:15:26","TRT02EDTM":"2023-10-14 15:15:26","AP01SDTM":"2020-10-13 21:15:26","AP01EDTM":"2022-10-14 09:15:26","AP02SDTM":"2022-10-14 09:15:26","AP02EDTM":"2023-10-14 15:15:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-14","EOSDY":1096,"LSTALVDT":"2023-11-02","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":937,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.83489,"AVALU":"U/L","BASE2":14.72899,"BASE":19.22055,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1059,"PCHG2":0.71897,"CHG":-4.38566,"PCHG":-22.81757,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-15 21:15:26","ADY":518,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-153","SUBJID":"id-153","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.79286,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 21:15:26","TRTEDTM":"2023-10-14 15:15:26","TRT01SDTM":"2020-10-13 21:15:26","TRT01EDTM":"2022-10-14 09:15:26","TRT02SDTM":"2022-10-14 09:15:26","TRT02EDTM":"2023-10-14 15:15:26","AP01SDTM":"2020-10-13 21:15:26","AP01EDTM":"2022-10-14 09:15:26","AP02SDTM":"2022-10-14 09:15:26","AP02EDTM":"2023-10-14 15:15:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-14","EOSDY":1096,"LSTALVDT":"2023-11-02","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5086,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.88803,"AVALU":"U/L","BASE2":14.72899,"BASE":19.22055,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.15904,"PCHG2":21.44779,"CHG":-1.33252,"PCHG":-6.93277,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-19 21:15:26","ADY":644,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-153","SUBJID":"id-153","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.79286,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 21:15:26","TRTEDTM":"2023-10-14 15:15:26","TRT01SDTM":"2020-10-13 21:15:26","TRT01EDTM":"2022-10-14 09:15:26","TRT02SDTM":"2022-10-14 09:15:26","TRT02EDTM":"2023-10-14 15:15:26","AP01SDTM":"2020-10-13 21:15:26","AP01EDTM":"2022-10-14 09:15:26","AP02SDTM":"2022-10-14 09:15:26","AP02EDTM":"2023-10-14 15:15:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-14","EOSDY":1096,"LSTALVDT":"2023-11-02","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3092,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.23879,"AVALU":"U/L","BASE2":14.72899,"BASE":19.22055,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.4902,"PCHG2":-91.58946,"CHG":-17.98176,"PCHG":-93.55488,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-07-31 21:15:26","ADY":656,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-153","SUBJID":"id-153","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.79286,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 21:15:26","TRTEDTM":"2023-10-14 15:15:26","TRT01SDTM":"2020-10-13 21:15:26","TRT01EDTM":"2022-10-14 09:15:26","TRT02SDTM":"2022-10-14 09:15:26","TRT02EDTM":"2023-10-14 15:15:26","AP01SDTM":"2020-10-13 21:15:26","AP01EDTM":"2022-10-14 09:15:26","AP02SDTM":"2022-10-14 09:15:26","AP02EDTM":"2023-10-14 15:15:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-14","EOSDY":1096,"LSTALVDT":"2023-11-02","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1756,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.20175,"AVALU":"U/L","BASE2":14.72899,"BASE":19.22055,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.47276,"PCHG2":77.89239,"CHG":6.9812,"PCHG":36.32156,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-18 21:15:26","ADY":886,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-153","SUBJID":"id-153","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.79286,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 21:15:26","TRTEDTM":"2023-10-14 15:15:26","TRT01SDTM":"2020-10-13 21:15:26","TRT01EDTM":"2022-10-14 09:15:26","TRT02SDTM":"2022-10-14 09:15:26","TRT02EDTM":"2023-10-14 15:15:26","AP01SDTM":"2020-10-13 21:15:26","AP01EDTM":"2022-10-14 09:15:26","AP02SDTM":"2022-10-14 09:15:26","AP02EDTM":"2023-10-14 15:15:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-14","EOSDY":1096,"LSTALVDT":"2023-11-02","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7154,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.33785,"AVALU":"mg/L","BASE2":9.33785,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-12-24 21:15:26","ADY":72,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-153","SUBJID":"id-153","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.79286,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 21:15:26","TRTEDTM":"2023-10-14 15:15:26","TRT01SDTM":"2020-10-13 21:15:26","TRT01EDTM":"2022-10-14 09:15:26","TRT02SDTM":"2022-10-14 09:15:26","TRT02EDTM":"2023-10-14 15:15:26","AP01SDTM":"2020-10-13 21:15:26","AP01EDTM":"2022-10-14 09:15:26","AP02SDTM":"2022-10-14 09:15:26","AP02EDTM":"2023-10-14 15:15:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-14","EOSDY":1096,"LSTALVDT":"2023-11-02","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3835,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.68223,"AVALU":"mg/L","BASE2":9.33785,"BASE":7.68223,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.65562,"PCHG2":-17.73021,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2020-12-29 21:15:26","ADY":77,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-153","SUBJID":"id-153","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.79286,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 21:15:26","TRTEDTM":"2023-10-14 15:15:26","TRT01SDTM":"2020-10-13 21:15:26","TRT01EDTM":"2022-10-14 09:15:26","TRT02SDTM":"2022-10-14 09:15:26","TRT02EDTM":"2023-10-14 15:15:26","AP01SDTM":"2020-10-13 21:15:26","AP01EDTM":"2022-10-14 09:15:26","AP02SDTM":"2022-10-14 09:15:26","AP02EDTM":"2023-10-14 15:15:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-14","EOSDY":1096,"LSTALVDT":"2023-11-02","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5526,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.48797,"AVALU":"mg/L","BASE2":9.33785,"BASE":7.68223,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.84988,"PCHG2":-9.10143,"CHG":0.80574,"PCHG":10.48839,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-06-10 21:15:26","ADY":240,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-153","SUBJID":"id-153","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.79286,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 21:15:26","TRTEDTM":"2023-10-14 15:15:26","TRT01SDTM":"2020-10-13 21:15:26","TRT01EDTM":"2022-10-14 09:15:26","TRT02SDTM":"2022-10-14 09:15:26","TRT02EDTM":"2023-10-14 15:15:26","AP01SDTM":"2020-10-13 21:15:26","AP01EDTM":"2022-10-14 09:15:26","AP02SDTM":"2022-10-14 09:15:26","AP02EDTM":"2023-10-14 15:15:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-14","EOSDY":1096,"LSTALVDT":"2023-11-02","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6829,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.23882,"AVALU":"mg/L","BASE2":9.33785,"BASE":7.68223,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.09903,"PCHG2":-11.76965,"CHG":0.55659,"PCHG":7.24514,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-03-15 21:15:26","ADY":518,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-153","SUBJID":"id-153","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.79286,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 21:15:26","TRTEDTM":"2023-10-14 15:15:26","TRT01SDTM":"2020-10-13 21:15:26","TRT01EDTM":"2022-10-14 09:15:26","TRT02SDTM":"2022-10-14 09:15:26","TRT02EDTM":"2023-10-14 15:15:26","AP01SDTM":"2020-10-13 21:15:26","AP01EDTM":"2022-10-14 09:15:26","AP02SDTM":"2022-10-14 09:15:26","AP02EDTM":"2023-10-14 15:15:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-14","EOSDY":1096,"LSTALVDT":"2023-11-02","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4781,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.64512,"AVALU":"mg/L","BASE2":9.33785,"BASE":7.68223,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.69273,"PCHG2":-7.41848,"CHG":0.96289,"PCHG":12.53404,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-07-19 21:15:26","ADY":644,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-153","SUBJID":"id-153","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.79286,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 21:15:26","TRTEDTM":"2023-10-14 15:15:26","TRT01SDTM":"2020-10-13 21:15:26","TRT01EDTM":"2022-10-14 09:15:26","TRT02SDTM":"2022-10-14 09:15:26","TRT02EDTM":"2023-10-14 15:15:26","AP01SDTM":"2020-10-13 21:15:26","AP01EDTM":"2022-10-14 09:15:26","AP02SDTM":"2022-10-14 09:15:26","AP02EDTM":"2023-10-14 15:15:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-14","EOSDY":1096,"LSTALVDT":"2023-11-02","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3227,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.3509,"AVALU":"mg/L","BASE2":9.33785,"BASE":7.68223,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.01305,"PCHG2":10.84883,"CHG":2.66867,"PCHG":34.7382,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"3","BTOXGR":"-2","ADTM":"2022-07-31 21:15:26","ADY":656,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-153","SUBJID":"id-153","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.79286,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 21:15:26","TRTEDTM":"2023-10-14 15:15:26","TRT01SDTM":"2020-10-13 21:15:26","TRT01EDTM":"2022-10-14 09:15:26","TRT02SDTM":"2022-10-14 09:15:26","TRT02EDTM":"2023-10-14 15:15:26","AP01SDTM":"2020-10-13 21:15:26","AP01EDTM":"2022-10-14 09:15:26","AP02SDTM":"2022-10-14 09:15:26","AP02EDTM":"2023-10-14 15:15:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-14","EOSDY":1096,"LSTALVDT":"2023-11-02","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":325,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.0823,"AVALU":"mg/L","BASE2":9.33785,"BASE":7.68223,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.25554,"PCHG2":-13.44576,"CHG":0.40008,"PCHG":5.20781,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2023-03-18 21:15:26","ADY":886,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-153","SUBJID":"id-153","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.79286,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 21:15:26","TRTEDTM":"2023-10-14 15:15:26","TRT01SDTM":"2020-10-13 21:15:26","TRT01EDTM":"2022-10-14 09:15:26","TRT02SDTM":"2022-10-14 09:15:26","TRT02EDTM":"2023-10-14 15:15:26","AP01SDTM":"2020-10-13 21:15:26","AP01EDTM":"2022-10-14 09:15:26","AP02SDTM":"2022-10-14 09:15:26","AP02EDTM":"2023-10-14 15:15:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-14","EOSDY":1096,"LSTALVDT":"2023-11-02","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3980,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97802,"AVALU":"g/L","BASE2":2.97802,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-24 21:15:26","ADY":72,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-153","SUBJID":"id-153","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.79286,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 21:15:26","TRTEDTM":"2023-10-14 15:15:26","TRT01SDTM":"2020-10-13 21:15:26","TRT01EDTM":"2022-10-14 09:15:26","TRT02SDTM":"2022-10-14 09:15:26","TRT02EDTM":"2023-10-14 15:15:26","AP01SDTM":"2020-10-13 21:15:26","AP01EDTM":"2022-10-14 09:15:26","AP02SDTM":"2022-10-14 09:15:26","AP02EDTM":"2023-10-14 15:15:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-14","EOSDY":1096,"LSTALVDT":"2023-11-02","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1642,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98849,"AVALU":"g/L","BASE2":2.97802,"BASE":2.98849,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.01047,"PCHG2":0.3516,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-29 21:15:26","ADY":77,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-153","SUBJID":"id-153","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.79286,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 21:15:26","TRTEDTM":"2023-10-14 15:15:26","TRT01SDTM":"2020-10-13 21:15:26","TRT01EDTM":"2022-10-14 09:15:26","TRT02SDTM":"2022-10-14 09:15:26","TRT02EDTM":"2023-10-14 15:15:26","AP01SDTM":"2020-10-13 21:15:26","AP01EDTM":"2022-10-14 09:15:26","AP02SDTM":"2022-10-14 09:15:26","AP02EDTM":"2023-10-14 15:15:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-14","EOSDY":1096,"LSTALVDT":"2023-11-02","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6804,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82627,"AVALU":"g/L","BASE2":2.97802,"BASE":2.98849,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15174,"PCHG2":-5.09549,"CHG":-0.16221,"PCHG":-5.428,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-10 21:15:26","ADY":240,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-153","SUBJID":"id-153","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.79286,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 21:15:26","TRTEDTM":"2023-10-14 15:15:26","TRT01SDTM":"2020-10-13 21:15:26","TRT01EDTM":"2022-10-14 09:15:26","TRT02SDTM":"2022-10-14 09:15:26","TRT02EDTM":"2023-10-14 15:15:26","AP01SDTM":"2020-10-13 21:15:26","AP01EDTM":"2022-10-14 09:15:26","AP02SDTM":"2022-10-14 09:15:26","AP02EDTM":"2023-10-14 15:15:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-14","EOSDY":1096,"LSTALVDT":"2023-11-02","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":536,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8348,"AVALU":"g/L","BASE2":2.97802,"BASE":2.98849,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14322,"PCHG2":-4.80913,"CHG":-0.15369,"PCHG":-5.14264,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-15 21:15:26","ADY":518,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-153","SUBJID":"id-153","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.79286,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 21:15:26","TRTEDTM":"2023-10-14 15:15:26","TRT01SDTM":"2020-10-13 21:15:26","TRT01EDTM":"2022-10-14 09:15:26","TRT02SDTM":"2022-10-14 09:15:26","TRT02EDTM":"2023-10-14 15:15:26","AP01SDTM":"2020-10-13 21:15:26","AP01EDTM":"2022-10-14 09:15:26","AP02SDTM":"2022-10-14 09:15:26","AP02EDTM":"2023-10-14 15:15:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-14","EOSDY":1096,"LSTALVDT":"2023-11-02","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5641,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91852,"AVALU":"g/L","BASE2":2.97802,"BASE":2.98849,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0595,"PCHG2":-1.99794,"CHG":-0.06997,"PCHG":-2.3413,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-19 21:15:26","ADY":644,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-153","SUBJID":"id-153","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.79286,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 21:15:26","TRTEDTM":"2023-10-14 15:15:26","TRT01SDTM":"2020-10-13 21:15:26","TRT01EDTM":"2022-10-14 09:15:26","TRT02SDTM":"2022-10-14 09:15:26","TRT02EDTM":"2023-10-14 15:15:26","AP01SDTM":"2020-10-13 21:15:26","AP01EDTM":"2022-10-14 09:15:26","AP02SDTM":"2022-10-14 09:15:26","AP02EDTM":"2023-10-14 15:15:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-14","EOSDY":1096,"LSTALVDT":"2023-11-02","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6582,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82578,"AVALU":"g/L","BASE2":2.97802,"BASE":2.98849,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15224,"PCHG2":-5.11212,"CHG":-0.16271,"PCHG":-5.44457,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-31 21:15:26","ADY":656,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-153","SUBJID":"id-153","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.79286,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-13 21:15:26","TRTEDTM":"2023-10-14 15:15:26","TRT01SDTM":"2020-10-13 21:15:26","TRT01EDTM":"2022-10-14 09:15:26","TRT02SDTM":"2022-10-14 09:15:26","TRT02EDTM":"2023-10-14 15:15:26","AP01SDTM":"2020-10-13 21:15:26","AP01EDTM":"2022-10-14 09:15:26","AP02SDTM":"2022-10-14 09:15:26","AP02EDTM":"2023-10-14 15:15:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-14","EOSDY":1096,"LSTALVDT":"2023-11-02","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6600,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90525,"AVALU":"g/L","BASE2":2.97802,"BASE":2.98849,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07277,"PCHG2":-2.44354,"CHG":-0.08324,"PCHG":-2.78534,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-18 21:15:26","ADY":886,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-158","SUBJID":"id-158","SITEID":"CHN-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.18135,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-20 00:53:04","TRTEDTM":"2023-07-20 18:53:04","TRT01SDTM":"2020-07-20 00:53:04","TRT01EDTM":"2022-07-20 12:53:04","TRT02SDTM":"2022-07-20 12:53:04","TRT02EDTM":"2023-07-20 18:53:04","AP01SDTM":"2020-07-20 00:53:04","AP01EDTM":"2022-07-20 12:53:04","AP02SDTM":"2022-07-20 12:53:04","AP02EDTM":"2023-07-20 18:53:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-07-31","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4953,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.24259,"AVALU":"U/L","BASE2":31.24259,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-23 00:53:04","ADY":187,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-158","SUBJID":"id-158","SITEID":"CHN-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.18135,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-20 00:53:04","TRTEDTM":"2023-07-20 18:53:04","TRT01SDTM":"2020-07-20 00:53:04","TRT01EDTM":"2022-07-20 12:53:04","TRT02SDTM":"2022-07-20 12:53:04","TRT02EDTM":"2023-07-20 18:53:04","AP01SDTM":"2020-07-20 00:53:04","AP01EDTM":"2022-07-20 12:53:04","AP02SDTM":"2022-07-20 12:53:04","AP02EDTM":"2023-07-20 18:53:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-07-31","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7332,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.59997,"AVALU":"U/L","BASE2":31.24259,"BASE":18.59997,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-12.64262,"PCHG2":-40.46599,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-06 00:53:04","ADY":229,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-158","SUBJID":"id-158","SITEID":"CHN-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.18135,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-20 00:53:04","TRTEDTM":"2023-07-20 18:53:04","TRT01SDTM":"2020-07-20 00:53:04","TRT01EDTM":"2022-07-20 12:53:04","TRT02SDTM":"2022-07-20 12:53:04","TRT02EDTM":"2023-07-20 18:53:04","AP01SDTM":"2020-07-20 00:53:04","AP01EDTM":"2022-07-20 12:53:04","AP02SDTM":"2022-07-20 12:53:04","AP02EDTM":"2023-07-20 18:53:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-07-31","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7133,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.17975,"AVALU":"U/L","BASE2":31.24259,"BASE":18.59997,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-18.06284,"PCHG2":-57.8148,"CHG":-5.42022,"PCHG":-29.14102,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-07 00:53:04","ADY":322,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-158","SUBJID":"id-158","SITEID":"CHN-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.18135,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-20 00:53:04","TRTEDTM":"2023-07-20 18:53:04","TRT01SDTM":"2020-07-20 00:53:04","TRT01EDTM":"2022-07-20 12:53:04","TRT02SDTM":"2022-07-20 12:53:04","TRT02EDTM":"2023-07-20 18:53:04","AP01SDTM":"2020-07-20 00:53:04","AP01EDTM":"2022-07-20 12:53:04","AP02SDTM":"2022-07-20 12:53:04","AP02EDTM":"2023-07-20 18:53:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-07-31","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3963,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.43518,"AVALU":"U/L","BASE2":31.24259,"BASE":18.59997,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.80741,"PCHG2":-44.19419,"CHG":-1.16479,"PCHG":-6.26231,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-23 00:53:04","ADY":368,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-158","SUBJID":"id-158","SITEID":"CHN-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.18135,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-20 00:53:04","TRTEDTM":"2023-07-20 18:53:04","TRT01SDTM":"2020-07-20 00:53:04","TRT01EDTM":"2022-07-20 12:53:04","TRT02SDTM":"2022-07-20 12:53:04","TRT02EDTM":"2023-07-20 18:53:04","AP01SDTM":"2020-07-20 00:53:04","AP01EDTM":"2022-07-20 12:53:04","AP02SDTM":"2022-07-20 12:53:04","AP02EDTM":"2023-07-20 18:53:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-07-31","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1718,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.17347,"AVALU":"U/L","BASE2":31.24259,"BASE":18.59997,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.93089,"PCHG2":2.97954,"CHG":13.57351,"PCHG":72.97598,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-09 00:53:04","ADY":416,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-158","SUBJID":"id-158","SITEID":"CHN-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.18135,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-20 00:53:04","TRTEDTM":"2023-07-20 18:53:04","TRT01SDTM":"2020-07-20 00:53:04","TRT01EDTM":"2022-07-20 12:53:04","TRT02SDTM":"2022-07-20 12:53:04","TRT02EDTM":"2023-07-20 18:53:04","AP01SDTM":"2020-07-20 00:53:04","AP01EDTM":"2022-07-20 12:53:04","AP02SDTM":"2022-07-20 12:53:04","AP02EDTM":"2023-07-20 18:53:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-07-31","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5888,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.81168,"AVALU":"U/L","BASE2":31.24259,"BASE":18.59997,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.43091,"PCHG2":-42.9891,"CHG":-0.78828,"PCHG":-4.2381,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-16 00:53:04","ADY":726,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-158","SUBJID":"id-158","SITEID":"CHN-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.18135,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-20 00:53:04","TRTEDTM":"2023-07-20 18:53:04","TRT01SDTM":"2020-07-20 00:53:04","TRT01EDTM":"2022-07-20 12:53:04","TRT02SDTM":"2022-07-20 12:53:04","TRT02EDTM":"2023-07-20 18:53:04","AP01SDTM":"2020-07-20 00:53:04","AP01EDTM":"2022-07-20 12:53:04","AP02SDTM":"2022-07-20 12:53:04","AP02EDTM":"2023-07-20 18:53:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-07-31","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":674,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.12287,"AVALU":"U/L","BASE2":31.24259,"BASE":18.59997,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-22.11971,"PCHG2":-70.79988,"CHG":-9.47709,"PCHG":-50.9522,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-30 00:53:04","ADY":893,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-158","SUBJID":"id-158","SITEID":"CHN-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.18135,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-20 00:53:04","TRTEDTM":"2023-07-20 18:53:04","TRT01SDTM":"2020-07-20 00:53:04","TRT01EDTM":"2022-07-20 12:53:04","TRT02SDTM":"2022-07-20 12:53:04","TRT02EDTM":"2023-07-20 18:53:04","AP01SDTM":"2020-07-20 00:53:04","AP01EDTM":"2022-07-20 12:53:04","AP02SDTM":"2022-07-20 12:53:04","AP02EDTM":"2023-07-20 18:53:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-07-31","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3339,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.78218,"AVALU":"mg/L","BASE2":10.78218,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-01-23 00:53:04","ADY":187,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-158","SUBJID":"id-158","SITEID":"CHN-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.18135,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-20 00:53:04","TRTEDTM":"2023-07-20 18:53:04","TRT01SDTM":"2020-07-20 00:53:04","TRT01EDTM":"2022-07-20 12:53:04","TRT02SDTM":"2022-07-20 12:53:04","TRT02EDTM":"2023-07-20 18:53:04","AP01SDTM":"2020-07-20 00:53:04","AP01EDTM":"2022-07-20 12:53:04","AP02SDTM":"2022-07-20 12:53:04","AP02EDTM":"2023-07-20 18:53:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-07-31","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5519,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.14319,"AVALU":"mg/L","BASE2":10.78218,"BASE":9.14319,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.63899,"PCHG2":-15.20092,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-06 00:53:04","ADY":229,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-158","SUBJID":"id-158","SITEID":"CHN-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.18135,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-20 00:53:04","TRTEDTM":"2023-07-20 18:53:04","TRT01SDTM":"2020-07-20 00:53:04","TRT01EDTM":"2022-07-20 12:53:04","TRT02SDTM":"2022-07-20 12:53:04","TRT02EDTM":"2023-07-20 18:53:04","AP01SDTM":"2020-07-20 00:53:04","AP01EDTM":"2022-07-20 12:53:04","AP02SDTM":"2022-07-20 12:53:04","AP02EDTM":"2023-07-20 18:53:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-07-31","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7404,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.98694,"AVALU":"mg/L","BASE2":10.78218,"BASE":9.14319,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.79524,"PCHG2":-7.37548,"CHG":0.84375,"PCHG":9.22821,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-07 00:53:04","ADY":322,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-158","SUBJID":"id-158","SITEID":"CHN-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.18135,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-20 00:53:04","TRTEDTM":"2023-07-20 18:53:04","TRT01SDTM":"2020-07-20 00:53:04","TRT01EDTM":"2022-07-20 12:53:04","TRT02SDTM":"2022-07-20 12:53:04","TRT02EDTM":"2023-07-20 18:53:04","AP01SDTM":"2020-07-20 00:53:04","AP01EDTM":"2022-07-20 12:53:04","AP02SDTM":"2022-07-20 12:53:04","AP02EDTM":"2023-07-20 18:53:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-07-31","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6874,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.03735,"AVALU":"mg/L","BASE2":10.78218,"BASE":9.14319,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.74483,"PCHG2":-16.1825,"CHG":-0.10584,"PCHG":-1.15754,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-23 00:53:04","ADY":368,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-158","SUBJID":"id-158","SITEID":"CHN-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.18135,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-20 00:53:04","TRTEDTM":"2023-07-20 18:53:04","TRT01SDTM":"2020-07-20 00:53:04","TRT01EDTM":"2022-07-20 12:53:04","TRT02SDTM":"2022-07-20 12:53:04","TRT02EDTM":"2023-07-20 18:53:04","AP01SDTM":"2020-07-20 00:53:04","AP01EDTM":"2022-07-20 12:53:04","AP02SDTM":"2022-07-20 12:53:04","AP02EDTM":"2023-07-20 18:53:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-07-31","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2811,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.67957,"AVALU":"mg/L","BASE2":10.78218,"BASE":9.14319,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.10261,"PCHG2":-10.2262,"CHG":0.53638,"PCHG":5.86648,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-09 00:53:04","ADY":416,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-158","SUBJID":"id-158","SITEID":"CHN-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.18135,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-20 00:53:04","TRTEDTM":"2023-07-20 18:53:04","TRT01SDTM":"2020-07-20 00:53:04","TRT01EDTM":"2022-07-20 12:53:04","TRT02SDTM":"2022-07-20 12:53:04","TRT02EDTM":"2023-07-20 18:53:04","AP01SDTM":"2020-07-20 00:53:04","AP01EDTM":"2022-07-20 12:53:04","AP02SDTM":"2022-07-20 12:53:04","AP02EDTM":"2023-07-20 18:53:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-07-31","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8347,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.29141,"AVALU":"mg/L","BASE2":10.78218,"BASE":9.14319,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.49077,"PCHG2":-23.10084,"CHG":-0.85178,"PCHG":-9.31604,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-16 00:53:04","ADY":726,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-158","SUBJID":"id-158","SITEID":"CHN-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.18135,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-20 00:53:04","TRTEDTM":"2023-07-20 18:53:04","TRT01SDTM":"2020-07-20 00:53:04","TRT01EDTM":"2022-07-20 12:53:04","TRT02SDTM":"2022-07-20 12:53:04","TRT02EDTM":"2023-07-20 18:53:04","AP01SDTM":"2020-07-20 00:53:04","AP01EDTM":"2022-07-20 12:53:04","AP02SDTM":"2022-07-20 12:53:04","AP02EDTM":"2023-07-20 18:53:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-07-31","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5224,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.29607,"AVALU":"mg/L","BASE2":10.78218,"BASE":9.14319,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.48611,"PCHG2":-13.78304,"CHG":0.15288,"PCHG":1.67205,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-30 00:53:04","ADY":893,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-158","SUBJID":"id-158","SITEID":"CHN-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.18135,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-20 00:53:04","TRTEDTM":"2023-07-20 18:53:04","TRT01SDTM":"2020-07-20 00:53:04","TRT01EDTM":"2022-07-20 12:53:04","TRT02SDTM":"2022-07-20 12:53:04","TRT02EDTM":"2023-07-20 18:53:04","AP01SDTM":"2020-07-20 00:53:04","AP01EDTM":"2022-07-20 12:53:04","AP02SDTM":"2022-07-20 12:53:04","AP02EDTM":"2023-07-20 18:53:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-07-31","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4387,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89538,"AVALU":"g/L","BASE2":2.89538,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-23 00:53:04","ADY":187,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-158","SUBJID":"id-158","SITEID":"CHN-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.18135,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-20 00:53:04","TRTEDTM":"2023-07-20 18:53:04","TRT01SDTM":"2020-07-20 00:53:04","TRT01EDTM":"2022-07-20 12:53:04","TRT02SDTM":"2022-07-20 12:53:04","TRT02EDTM":"2023-07-20 18:53:04","AP01SDTM":"2020-07-20 00:53:04","AP01EDTM":"2022-07-20 12:53:04","AP02SDTM":"2022-07-20 12:53:04","AP02EDTM":"2023-07-20 18:53:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-07-31","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4108,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99423,"AVALU":"g/L","BASE2":2.89538,"BASE":2.99423,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.09886,"PCHG2":3.4143,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-06 00:53:04","ADY":229,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-158","SUBJID":"id-158","SITEID":"CHN-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.18135,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-20 00:53:04","TRTEDTM":"2023-07-20 18:53:04","TRT01SDTM":"2020-07-20 00:53:04","TRT01EDTM":"2022-07-20 12:53:04","TRT02SDTM":"2022-07-20 12:53:04","TRT02EDTM":"2023-07-20 18:53:04","AP01SDTM":"2020-07-20 00:53:04","AP01EDTM":"2022-07-20 12:53:04","AP02SDTM":"2022-07-20 12:53:04","AP02EDTM":"2023-07-20 18:53:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-07-31","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8155,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92336,"AVALU":"g/L","BASE2":2.89538,"BASE":2.99423,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02799,"PCHG2":0.96663,"CHG":-0.07087,"PCHG":-2.36685,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-07 00:53:04","ADY":322,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-158","SUBJID":"id-158","SITEID":"CHN-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.18135,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-20 00:53:04","TRTEDTM":"2023-07-20 18:53:04","TRT01SDTM":"2020-07-20 00:53:04","TRT01EDTM":"2022-07-20 12:53:04","TRT02SDTM":"2022-07-20 12:53:04","TRT02EDTM":"2023-07-20 18:53:04","AP01SDTM":"2020-07-20 00:53:04","AP01EDTM":"2022-07-20 12:53:04","AP02SDTM":"2022-07-20 12:53:04","AP02EDTM":"2023-07-20 18:53:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-07-31","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2346,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93125,"AVALU":"g/L","BASE2":2.89538,"BASE":2.99423,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03587,"PCHG2":1.23899,"CHG":-0.06298,"PCHG":-2.10349,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-23 00:53:04","ADY":368,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-158","SUBJID":"id-158","SITEID":"CHN-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.18135,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-20 00:53:04","TRTEDTM":"2023-07-20 18:53:04","TRT01SDTM":"2020-07-20 00:53:04","TRT01EDTM":"2022-07-20 12:53:04","TRT02SDTM":"2022-07-20 12:53:04","TRT02EDTM":"2023-07-20 18:53:04","AP01SDTM":"2020-07-20 00:53:04","AP01EDTM":"2022-07-20 12:53:04","AP02SDTM":"2022-07-20 12:53:04","AP02EDTM":"2023-07-20 18:53:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-07-31","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2059,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04846,"AVALU":"g/L","BASE2":2.89538,"BASE":2.99423,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15309,"PCHG2":5.28736,"CHG":0.05423,"PCHG":1.81123,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-09-09 00:53:04","ADY":416,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-158","SUBJID":"id-158","SITEID":"CHN-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.18135,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-20 00:53:04","TRTEDTM":"2023-07-20 18:53:04","TRT01SDTM":"2020-07-20 00:53:04","TRT01EDTM":"2022-07-20 12:53:04","TRT02SDTM":"2022-07-20 12:53:04","TRT02EDTM":"2023-07-20 18:53:04","AP01SDTM":"2020-07-20 00:53:04","AP01EDTM":"2022-07-20 12:53:04","AP02SDTM":"2022-07-20 12:53:04","AP02EDTM":"2023-07-20 18:53:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-07-31","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2378,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93639,"AVALU":"g/L","BASE2":2.89538,"BASE":2.99423,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04102,"PCHG2":1.41672,"CHG":-0.05784,"PCHG":-1.93162,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-16 00:53:04","ADY":726,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-158","SUBJID":"id-158","SITEID":"CHN-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.18135,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-20 00:53:04","TRTEDTM":"2023-07-20 18:53:04","TRT01SDTM":"2020-07-20 00:53:04","TRT01EDTM":"2022-07-20 12:53:04","TRT02SDTM":"2022-07-20 12:53:04","TRT02EDTM":"2023-07-20 18:53:04","AP01SDTM":"2020-07-20 00:53:04","AP01EDTM":"2022-07-20 12:53:04","AP02SDTM":"2022-07-20 12:53:04","AP02EDTM":"2023-07-20 18:53:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-07-31","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6758,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9304,"AVALU":"g/L","BASE2":2.89538,"BASE":2.99423,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03503,"PCHG2":1.20982,"CHG":-0.06383,"PCHG":-2.1317,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-30 00:53:04","ADY":893,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-167","SUBJID":"id-167","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.96265,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-07","TRTSDTM":"2019-11-08 14:18:56","TRT01SDTM":"2019-11-08 14:18:56","AP01SDTM":"2019-11-08 14:18:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8321,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.7172,"AVALU":"U/L","BASE2":12.7172,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-13 14:18:56","ADY":126,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-167","SUBJID":"id-167","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.96265,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-07","TRTSDTM":"2019-11-08 14:18:56","TRT01SDTM":"2019-11-08 14:18:56","AP01SDTM":"2019-11-08 14:18:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2410,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.60178,"AVALU":"U/L","BASE2":12.7172,"BASE":25.60178,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":12.88458,"PCHG2":101.31613,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-03 14:18:56","ADY":208,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-167","SUBJID":"id-167","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.96265,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-07","TRTSDTM":"2019-11-08 14:18:56","TRT01SDTM":"2019-11-08 14:18:56","AP01SDTM":"2019-11-08 14:18:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6658,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.03325,"AVALU":"U/L","BASE2":12.7172,"BASE":25.60178,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.68395,"PCHG2":-60.4217,"CHG":-20.56852,"PCHG":-80.34022,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-07-08 14:18:56","ADY":243,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-167","SUBJID":"id-167","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.96265,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-07","TRTSDTM":"2019-11-08 14:18:56","TRT01SDTM":"2019-11-08 14:18:56","AP01SDTM":"2019-11-08 14:18:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7681,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.56828,"AVALU":"U/L","BASE2":12.7172,"BASE":25.60178,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.85108,"PCHG2":22.41905,"CHG":-10.0335,"PCHG":-39.19064,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-21 14:18:56","ADY":409,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-167","SUBJID":"id-167","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.96265,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-07","TRTSDTM":"2019-11-08 14:18:56","TRT01SDTM":"2019-11-08 14:18:56","AP01SDTM":"2019-11-08 14:18:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2864,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.71198,"AVALU":"U/L","BASE2":12.7172,"BASE":25.60178,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.99478,"PCHG2":125.77283,"CHG":3.11021,"PCHG":12.14841,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-04 14:18:56","ADY":482,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-167","SUBJID":"id-167","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.96265,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-07","TRTSDTM":"2019-11-08 14:18:56","TRT01SDTM":"2019-11-08 14:18:56","AP01SDTM":"2019-11-08 14:18:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6624,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.84549,"AVALU":"U/L","BASE2":12.7172,"BASE":25.60178,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.12829,"PCHG2":87.50581,"CHG":-1.75629,"PCHG":-6.86002,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-05 14:18:56","ADY":544,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-167","SUBJID":"id-167","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.96265,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-07","TRTSDTM":"2019-11-08 14:18:56","TRT01SDTM":"2019-11-08 14:18:56","AP01SDTM":"2019-11-08 14:18:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5434,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.83453,"AVALU":"U/L","BASE2":12.7172,"BASE":25.60178,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.11733,"PCHG2":55.96613,"CHG":-5.76725,"PCHG":-22.52676,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-20 14:18:56","ADY":682,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-167","SUBJID":"id-167","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.96265,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-07","TRTSDTM":"2019-11-08 14:18:56","TRT01SDTM":"2019-11-08 14:18:56","AP01SDTM":"2019-11-08 14:18:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":366,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.16825,"AVALU":"mg/L","BASE2":7.16825,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-03-13 14:18:56","ADY":126,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-167","SUBJID":"id-167","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.96265,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-07","TRTSDTM":"2019-11-08 14:18:56","TRT01SDTM":"2019-11-08 14:18:56","AP01SDTM":"2019-11-08 14:18:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1502,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.09319,"AVALU":"mg/L","BASE2":7.16825,"BASE":8.09319,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.92494,"PCHG2":12.90331,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-03 14:18:56","ADY":208,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-167","SUBJID":"id-167","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.96265,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-07","TRTSDTM":"2019-11-08 14:18:56","TRT01SDTM":"2019-11-08 14:18:56","AP01SDTM":"2019-11-08 14:18:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3314,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.64908,"AVALU":"mg/L","BASE2":7.16825,"BASE":8.09319,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.48083,"PCHG2":34.6086,"CHG":1.55589,"PCHG":19.22466,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-08 14:18:56","ADY":243,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-167","SUBJID":"id-167","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.96265,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-07","TRTSDTM":"2019-11-08 14:18:56","TRT01SDTM":"2019-11-08 14:18:56","AP01SDTM":"2019-11-08 14:18:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1676,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.83237,"AVALU":"mg/L","BASE2":7.16825,"BASE":8.09319,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.66412,"PCHG2":37.16552,"CHG":1.73918,"PCHG":21.48937,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-21 14:18:56","ADY":409,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-167","SUBJID":"id-167","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.96265,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-07","TRTSDTM":"2019-11-08 14:18:56","TRT01SDTM":"2019-11-08 14:18:56","AP01SDTM":"2019-11-08 14:18:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7000,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.90875,"AVALU":"mg/L","BASE2":7.16825,"BASE":8.09319,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.7405,"PCHG2":24.28065,"CHG":0.81556,"PCHG":10.07706,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-04 14:18:56","ADY":482,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-167","SUBJID":"id-167","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.96265,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-07","TRTSDTM":"2019-11-08 14:18:56","TRT01SDTM":"2019-11-08 14:18:56","AP01SDTM":"2019-11-08 14:18:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3542,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.22414,"AVALU":"mg/L","BASE2":7.16825,"BASE":8.09319,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.05589,"PCHG2":42.63093,"CHG":2.13095,"PCHG":26.33015,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-05-05 14:18:56","ADY":544,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-167","SUBJID":"id-167","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.96265,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-07","TRTSDTM":"2019-11-08 14:18:56","TRT01SDTM":"2019-11-08 14:18:56","AP01SDTM":"2019-11-08 14:18:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":716,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.05631,"AVALU":"mg/L","BASE2":7.16825,"BASE":8.09319,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.88806,"PCHG2":40.28958,"CHG":1.96312,"PCHG":24.25639,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-09-20 14:18:56","ADY":682,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-167","SUBJID":"id-167","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.96265,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-07","TRTSDTM":"2019-11-08 14:18:56","TRT01SDTM":"2019-11-08 14:18:56","AP01SDTM":"2019-11-08 14:18:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2561,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.09899,"AVALU":"g/L","BASE2":3.09899,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"2","ADTM":"2020-03-13 14:18:56","ADY":126,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-167","SUBJID":"id-167","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.96265,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-07","TRTSDTM":"2019-11-08 14:18:56","TRT01SDTM":"2019-11-08 14:18:56","AP01SDTM":"2019-11-08 14:18:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3250,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03095,"AVALU":"g/L","BASE2":3.09899,"BASE":3.03095,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.06804,"PCHG2":-2.1954,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2020-06-03 14:18:56","ADY":208,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-167","SUBJID":"id-167","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.96265,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-07","TRTSDTM":"2019-11-08 14:18:56","TRT01SDTM":"2019-11-08 14:18:56","AP01SDTM":"2019-11-08 14:18:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2486,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90621,"AVALU":"g/L","BASE2":3.09899,"BASE":3.03095,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19278,"PCHG2":-6.2208,"CHG":-0.12475,"PCHG":-4.11576,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2020-07-08 14:18:56","ADY":243,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-167","SUBJID":"id-167","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.96265,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-07","TRTSDTM":"2019-11-08 14:18:56","TRT01SDTM":"2019-11-08 14:18:56","AP01SDTM":"2019-11-08 14:18:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7165,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89304,"AVALU":"g/L","BASE2":3.09899,"BASE":3.03095,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20595,"PCHG2":-6.64568,"CHG":-0.13791,"PCHG":-4.55017,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2020-12-21 14:18:56","ADY":409,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-167","SUBJID":"id-167","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.96265,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-07","TRTSDTM":"2019-11-08 14:18:56","TRT01SDTM":"2019-11-08 14:18:56","AP01SDTM":"2019-11-08 14:18:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2970,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97656,"AVALU":"g/L","BASE2":3.09899,"BASE":3.03095,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12243,"PCHG2":-3.95058,"CHG":-0.05439,"PCHG":-1.79457,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-03-04 14:18:56","ADY":482,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-167","SUBJID":"id-167","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.96265,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-07","TRTSDTM":"2019-11-08 14:18:56","TRT01SDTM":"2019-11-08 14:18:56","AP01SDTM":"2019-11-08 14:18:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6675,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74103,"AVALU":"g/L","BASE2":3.09899,"BASE":3.03095,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.35795,"PCHG2":-11.55069,"CHG":-0.28992,"PCHG":-9.56528,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-05-05 14:18:56","ADY":544,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-167","SUBJID":"id-167","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.96265,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-07","TRTSDTM":"2019-11-08 14:18:56","TRT01SDTM":"2019-11-08 14:18:56","AP01SDTM":"2019-11-08 14:18:56","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3315,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04311,"AVALU":"g/L","BASE2":3.09899,"BASE":3.03095,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05587,"PCHG2":-1.80296,"CHG":0.01216,"PCHG":0.40125,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"1","BTOXGR":"2","ADTM":"2021-09-20 14:18:56","ADY":682,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-174","SUBJID":"id-174","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08848,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-19 21:07:01","TRTEDTM":"2023-05-20 15:07:01","TRT01SDTM":"2020-05-19 21:07:01","TRT01EDTM":"2022-05-20 09:07:01","TRT02SDTM":"2022-05-20 09:07:01","TRT02EDTM":"2023-05-20 15:07:01","AP01SDTM":"2020-05-19 21:07:01","AP01EDTM":"2022-05-20 09:07:01","AP02SDTM":"2022-05-20 09:07:01","AP02EDTM":"2023-05-20 15:07:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-20","EOSDY":1096,"LSTALVDT":"2023-06-01","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3779,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.03096,"AVALU":"U/L","BASE2":6.03096,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-07-04 21:07:01","ADY":46,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-174","SUBJID":"id-174","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08848,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-19 21:07:01","TRTEDTM":"2023-05-20 15:07:01","TRT01SDTM":"2020-05-19 21:07:01","TRT01EDTM":"2022-05-20 09:07:01","TRT02SDTM":"2022-05-20 09:07:01","TRT02EDTM":"2023-05-20 15:07:01","AP01SDTM":"2020-05-19 21:07:01","AP01EDTM":"2022-05-20 09:07:01","AP02SDTM":"2022-05-20 09:07:01","AP02EDTM":"2023-05-20 15:07:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-20","EOSDY":1096,"LSTALVDT":"2023-06-01","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6460,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.58483,"AVALU":"U/L","BASE2":6.03096,"BASE":20.58483,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":14.55386,"PCHG2":241.3191,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-17 21:07:01","ADY":302,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-174","SUBJID":"id-174","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08848,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-19 21:07:01","TRTEDTM":"2023-05-20 15:07:01","TRT01SDTM":"2020-05-19 21:07:01","TRT01EDTM":"2022-05-20 09:07:01","TRT02SDTM":"2022-05-20 09:07:01","TRT02EDTM":"2023-05-20 15:07:01","AP01SDTM":"2020-05-19 21:07:01","AP01EDTM":"2022-05-20 09:07:01","AP02SDTM":"2022-05-20 09:07:01","AP02EDTM":"2023-05-20 15:07:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-20","EOSDY":1096,"LSTALVDT":"2023-06-01","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":868,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.7532,"AVALU":"U/L","BASE2":6.03096,"BASE":20.58483,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":25.72224,"PCHG2":426.50313,"CHG":11.16838,"PCHG":54.25539,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-31 21:07:01","ADY":469,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-174","SUBJID":"id-174","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08848,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-19 21:07:01","TRTEDTM":"2023-05-20 15:07:01","TRT01SDTM":"2020-05-19 21:07:01","TRT01EDTM":"2022-05-20 09:07:01","TRT02SDTM":"2022-05-20 09:07:01","TRT02EDTM":"2023-05-20 15:07:01","AP01SDTM":"2020-05-19 21:07:01","AP01EDTM":"2022-05-20 09:07:01","AP02SDTM":"2022-05-20 09:07:01","AP02EDTM":"2023-05-20 15:07:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-20","EOSDY":1096,"LSTALVDT":"2023-06-01","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2706,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.27306,"AVALU":"U/L","BASE2":6.03096,"BASE":20.58483,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":26.24209,"PCHG2":435.12283,"CHG":11.68823,"PCHG":56.7808,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-31 21:07:01","ADY":622,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-174","SUBJID":"id-174","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08848,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-19 21:07:01","TRTEDTM":"2023-05-20 15:07:01","TRT01SDTM":"2020-05-19 21:07:01","TRT01EDTM":"2022-05-20 09:07:01","TRT02SDTM":"2022-05-20 09:07:01","TRT02EDTM":"2023-05-20 15:07:01","AP01SDTM":"2020-05-19 21:07:01","AP01EDTM":"2022-05-20 09:07:01","AP02SDTM":"2022-05-20 09:07:01","AP02EDTM":"2023-05-20 15:07:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-20","EOSDY":1096,"LSTALVDT":"2023-06-01","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":409,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.02638,"AVALU":"U/L","BASE2":6.03096,"BASE":20.58483,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.99541,"PCHG2":115.99169,"CHG":-7.55845,"PCHG":-36.71855,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-23 21:07:01","ADY":704,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-174","SUBJID":"id-174","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08848,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-19 21:07:01","TRTEDTM":"2023-05-20 15:07:01","TRT01SDTM":"2020-05-19 21:07:01","TRT01EDTM":"2022-05-20 09:07:01","TRT02SDTM":"2022-05-20 09:07:01","TRT02EDTM":"2023-05-20 15:07:01","AP01SDTM":"2020-05-19 21:07:01","AP01EDTM":"2022-05-20 09:07:01","AP02SDTM":"2022-05-20 09:07:01","AP02EDTM":"2023-05-20 15:07:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-20","EOSDY":1096,"LSTALVDT":"2023-06-01","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":731,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.73128,"AVALU":"U/L","BASE2":6.03096,"BASE":20.58483,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.70031,"PCHG2":227.16632,"CHG":-0.85355,"PCHG":-4.1465,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-09 21:07:01","ADY":720,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-174","SUBJID":"id-174","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08848,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-19 21:07:01","TRTEDTM":"2023-05-20 15:07:01","TRT01SDTM":"2020-05-19 21:07:01","TRT01EDTM":"2022-05-20 09:07:01","TRT02SDTM":"2022-05-20 09:07:01","TRT02EDTM":"2023-05-20 15:07:01","AP01SDTM":"2020-05-19 21:07:01","AP01EDTM":"2022-05-20 09:07:01","AP02SDTM":"2022-05-20 09:07:01","AP02EDTM":"2023-05-20 15:07:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-20","EOSDY":1096,"LSTALVDT":"2023-06-01","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8049,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":36.14033,"AVALU":"U/L","BASE2":6.03096,"BASE":20.58483,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":30.10937,"PCHG2":499.24657,"CHG":15.55551,"PCHG":75.56784,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-04 21:07:01","ADY":746,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-174","SUBJID":"id-174","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08848,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-19 21:07:01","TRTEDTM":"2023-05-20 15:07:01","TRT01SDTM":"2020-05-19 21:07:01","TRT01EDTM":"2022-05-20 09:07:01","TRT02SDTM":"2022-05-20 09:07:01","TRT02EDTM":"2023-05-20 15:07:01","AP01SDTM":"2020-05-19 21:07:01","AP01EDTM":"2022-05-20 09:07:01","AP02SDTM":"2022-05-20 09:07:01","AP02EDTM":"2023-05-20 15:07:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-20","EOSDY":1096,"LSTALVDT":"2023-06-01","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6886,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.35745,"AVALU":"mg/L","BASE2":9.35745,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"2","ADTM":"2020-07-04 21:07:01","ADY":46,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-174","SUBJID":"id-174","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08848,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-19 21:07:01","TRTEDTM":"2023-05-20 15:07:01","TRT01SDTM":"2020-05-19 21:07:01","TRT01EDTM":"2022-05-20 09:07:01","TRT02SDTM":"2022-05-20 09:07:01","TRT02EDTM":"2023-05-20 15:07:01","AP01SDTM":"2020-05-19 21:07:01","AP01EDTM":"2022-05-20 09:07:01","AP02SDTM":"2022-05-20 09:07:01","AP02EDTM":"2023-05-20 15:07:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-20","EOSDY":1096,"LSTALVDT":"2023-06-01","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":162,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.29804,"AVALU":"mg/L","BASE2":9.35745,"BASE":10.29804,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.94059,"PCHG2":10.05179,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2021-03-17 21:07:01","ADY":302,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-174","SUBJID":"id-174","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08848,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-19 21:07:01","TRTEDTM":"2023-05-20 15:07:01","TRT01SDTM":"2020-05-19 21:07:01","TRT01EDTM":"2022-05-20 09:07:01","TRT02SDTM":"2022-05-20 09:07:01","TRT02EDTM":"2023-05-20 15:07:01","AP01SDTM":"2020-05-19 21:07:01","AP01EDTM":"2022-05-20 09:07:01","AP02SDTM":"2022-05-20 09:07:01","AP02EDTM":"2023-05-20 15:07:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-20","EOSDY":1096,"LSTALVDT":"2023-06-01","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":926,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.45355,"AVALU":"mg/L","BASE2":9.35745,"BASE":10.29804,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.9039,"PCHG2":-20.34633,"CHG":-2.84449,"PCHG":-27.62165,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-2","BTOXGR":"2","ADTM":"2021-08-31 21:07:01","ADY":469,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-174","SUBJID":"id-174","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08848,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-19 21:07:01","TRTEDTM":"2023-05-20 15:07:01","TRT01SDTM":"2020-05-19 21:07:01","TRT01EDTM":"2022-05-20 09:07:01","TRT02SDTM":"2022-05-20 09:07:01","TRT02EDTM":"2023-05-20 15:07:01","AP01SDTM":"2020-05-19 21:07:01","AP01EDTM":"2022-05-20 09:07:01","AP02SDTM":"2022-05-20 09:07:01","AP02EDTM":"2023-05-20 15:07:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-20","EOSDY":1096,"LSTALVDT":"2023-06-01","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5082,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.92768,"AVALU":"mg/L","BASE2":9.35745,"BASE":10.29804,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.57023,"PCHG2":6.09386,"CHG":-0.37036,"PCHG":-3.59642,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-01-31 21:07:01","ADY":622,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-174","SUBJID":"id-174","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08848,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-19 21:07:01","TRTEDTM":"2023-05-20 15:07:01","TRT01SDTM":"2020-05-19 21:07:01","TRT01EDTM":"2022-05-20 09:07:01","TRT02SDTM":"2022-05-20 09:07:01","TRT02EDTM":"2023-05-20 15:07:01","AP01SDTM":"2020-05-19 21:07:01","AP01EDTM":"2022-05-20 09:07:01","AP02SDTM":"2022-05-20 09:07:01","AP02EDTM":"2023-05-20 15:07:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-20","EOSDY":1096,"LSTALVDT":"2023-06-01","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8342,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.66218,"AVALU":"mg/L","BASE2":9.35745,"BASE":10.29804,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.69527,"PCHG2":-18.11678,"CHG":-2.63586,"PCHG":-25.59573,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-3","BTOXGR":"2","ADTM":"2022-04-23 21:07:01","ADY":704,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-174","SUBJID":"id-174","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08848,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-19 21:07:01","TRTEDTM":"2023-05-20 15:07:01","TRT01SDTM":"2020-05-19 21:07:01","TRT01EDTM":"2022-05-20 09:07:01","TRT02SDTM":"2022-05-20 09:07:01","TRT02EDTM":"2023-05-20 15:07:01","AP01SDTM":"2020-05-19 21:07:01","AP01EDTM":"2022-05-20 09:07:01","AP02SDTM":"2022-05-20 09:07:01","AP02EDTM":"2023-05-20 15:07:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-20","EOSDY":1096,"LSTALVDT":"2023-06-01","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7281,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.93691,"AVALU":"mg/L","BASE2":9.35745,"BASE":10.29804,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.42054,"PCHG2":-4.49417,"CHG":-1.36113,"PCHG":-13.21738,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-05-09 21:07:01","ADY":720,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-174","SUBJID":"id-174","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08848,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-19 21:07:01","TRTEDTM":"2023-05-20 15:07:01","TRT01SDTM":"2020-05-19 21:07:01","TRT01EDTM":"2022-05-20 09:07:01","TRT02SDTM":"2022-05-20 09:07:01","TRT02EDTM":"2023-05-20 15:07:01","AP01SDTM":"2020-05-19 21:07:01","AP01EDTM":"2022-05-20 09:07:01","AP02SDTM":"2022-05-20 09:07:01","AP02EDTM":"2023-05-20 15:07:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-20","EOSDY":1096,"LSTALVDT":"2023-06-01","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6095,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.00516,"AVALU":"mg/L","BASE2":9.35745,"BASE":10.29804,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.64771,"PCHG2":6.92192,"CHG":-0.29288,"PCHG":-2.84399,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"2","ADTM":"2022-06-04 21:07:01","ADY":746,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-174","SUBJID":"id-174","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08848,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-19 21:07:01","TRTEDTM":"2023-05-20 15:07:01","TRT01SDTM":"2020-05-19 21:07:01","TRT01EDTM":"2022-05-20 09:07:01","TRT02SDTM":"2022-05-20 09:07:01","TRT02EDTM":"2023-05-20 15:07:01","AP01SDTM":"2020-05-19 21:07:01","AP01EDTM":"2022-05-20 09:07:01","AP02SDTM":"2022-05-20 09:07:01","AP02EDTM":"2023-05-20 15:07:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-20","EOSDY":1096,"LSTALVDT":"2023-06-01","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1970,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05957,"AVALU":"g/L","BASE2":3.05957,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-07-04 21:07:01","ADY":46,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-174","SUBJID":"id-174","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08848,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-19 21:07:01","TRTEDTM":"2023-05-20 15:07:01","TRT01SDTM":"2020-05-19 21:07:01","TRT01EDTM":"2022-05-20 09:07:01","TRT02SDTM":"2022-05-20 09:07:01","TRT02EDTM":"2023-05-20 15:07:01","AP01SDTM":"2020-05-19 21:07:01","AP01EDTM":"2022-05-20 09:07:01","AP02SDTM":"2022-05-20 09:07:01","AP02EDTM":"2023-05-20 15:07:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-20","EOSDY":1096,"LSTALVDT":"2023-06-01","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5797,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86641,"AVALU":"g/L","BASE2":3.05957,"BASE":2.86641,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.19317,"PCHG2":-6.31349,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-17 21:07:01","ADY":302,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-174","SUBJID":"id-174","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08848,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-19 21:07:01","TRTEDTM":"2023-05-20 15:07:01","TRT01SDTM":"2020-05-19 21:07:01","TRT01EDTM":"2022-05-20 09:07:01","TRT02SDTM":"2022-05-20 09:07:01","TRT02EDTM":"2023-05-20 15:07:01","AP01SDTM":"2020-05-19 21:07:01","AP01EDTM":"2022-05-20 09:07:01","AP02SDTM":"2022-05-20 09:07:01","AP02EDTM":"2023-05-20 15:07:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-20","EOSDY":1096,"LSTALVDT":"2023-06-01","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7490,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99527,"AVALU":"g/L","BASE2":3.05957,"BASE":2.86641,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0643,"PCHG2":-2.10166,"CHG":0.12886,"PCHG":4.49566,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-31 21:07:01","ADY":469,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-174","SUBJID":"id-174","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08848,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-19 21:07:01","TRTEDTM":"2023-05-20 15:07:01","TRT01SDTM":"2020-05-19 21:07:01","TRT01EDTM":"2022-05-20 09:07:01","TRT02SDTM":"2022-05-20 09:07:01","TRT02EDTM":"2023-05-20 15:07:01","AP01SDTM":"2020-05-19 21:07:01","AP01EDTM":"2022-05-20 09:07:01","AP02SDTM":"2022-05-20 09:07:01","AP02EDTM":"2023-05-20 15:07:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-20","EOSDY":1096,"LSTALVDT":"2023-06-01","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5000,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90275,"AVALU":"g/L","BASE2":3.05957,"BASE":2.86641,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15682,"PCHG2":-5.12555,"CHG":0.03635,"PCHG":1.26799,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-31 21:07:01","ADY":622,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-174","SUBJID":"id-174","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08848,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-19 21:07:01","TRTEDTM":"2023-05-20 15:07:01","TRT01SDTM":"2020-05-19 21:07:01","TRT01EDTM":"2022-05-20 09:07:01","TRT02SDTM":"2022-05-20 09:07:01","TRT02EDTM":"2023-05-20 15:07:01","AP01SDTM":"2020-05-19 21:07:01","AP01EDTM":"2022-05-20 09:07:01","AP02SDTM":"2022-05-20 09:07:01","AP02EDTM":"2023-05-20 15:07:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-20","EOSDY":1096,"LSTALVDT":"2023-06-01","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":381,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86325,"AVALU":"g/L","BASE2":3.05957,"BASE":2.86641,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19633,"PCHG2":-6.41682,"CHG":-0.00316,"PCHG":-0.1103,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-23 21:07:01","ADY":704,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-174","SUBJID":"id-174","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08848,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-19 21:07:01","TRTEDTM":"2023-05-20 15:07:01","TRT01SDTM":"2020-05-19 21:07:01","TRT01EDTM":"2022-05-20 09:07:01","TRT02SDTM":"2022-05-20 09:07:01","TRT02EDTM":"2023-05-20 15:07:01","AP01SDTM":"2020-05-19 21:07:01","AP01EDTM":"2022-05-20 09:07:01","AP02SDTM":"2022-05-20 09:07:01","AP02EDTM":"2023-05-20 15:07:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-20","EOSDY":1096,"LSTALVDT":"2023-06-01","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5397,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81089,"AVALU":"g/L","BASE2":3.05957,"BASE":2.86641,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.24868,"PCHG2":-8.12804,"CHG":-0.05552,"PCHG":-1.93683,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-09 21:07:01","ADY":720,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-174","SUBJID":"id-174","SITEID":"CHN-11","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.08848,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-19 21:07:01","TRTEDTM":"2023-05-20 15:07:01","TRT01SDTM":"2020-05-19 21:07:01","TRT01EDTM":"2022-05-20 09:07:01","TRT02SDTM":"2022-05-20 09:07:01","TRT02EDTM":"2023-05-20 15:07:01","AP01SDTM":"2020-05-19 21:07:01","AP01EDTM":"2022-05-20 09:07:01","AP02SDTM":"2022-05-20 09:07:01","AP02EDTM":"2023-05-20 15:07:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-20","EOSDY":1096,"LSTALVDT":"2023-06-01","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4664,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.08348,"AVALU":"g/L","BASE2":3.05957,"BASE":2.86641,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02391,"PCHG2":0.78138,"CHG":0.21707,"PCHG":7.57298,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-06-04 21:07:01","ADY":746,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-184","SUBJID":"id-184","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.63913,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-04","TRTSDTM":"2019-05-04 08:19:47","TRTEDTM":"2022-02-15 03:30:55","TRT01SDTM":"2019-05-04 08:19:47","TRT01EDTM":"2021-02-14 21:30:55","TRT02SDTM":"2021-02-14 21:30:55","TRT02EDTM":"2022-02-15 03:30:55","AP01SDTM":"2019-05-04 08:19:47","AP01EDTM":"2021-02-14 21:30:55","AP02SDTM":"2021-02-14 21:30:55","AP02EDTM":"2022-02-15 03:30:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1018,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":1029,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1179,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.40687,"AVALU":"U/L","BASE2":17.40687,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-04 08:19:47","ADY":153,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-184","SUBJID":"id-184","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.63913,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-04","TRTSDTM":"2019-05-04 08:19:47","TRTEDTM":"2022-02-15 03:30:55","TRT01SDTM":"2019-05-04 08:19:47","TRT01EDTM":"2021-02-14 21:30:55","TRT02SDTM":"2021-02-14 21:30:55","TRT02EDTM":"2022-02-15 03:30:55","AP01SDTM":"2019-05-04 08:19:47","AP01EDTM":"2021-02-14 21:30:55","AP02SDTM":"2021-02-14 21:30:55","AP02EDTM":"2022-02-15 03:30:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1018,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":1029,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5122,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.82247,"AVALU":"U/L","BASE2":17.40687,"BASE":22.82247,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":5.41561,"PCHG2":31.1119,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-27 08:19:47","ADY":176,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-184","SUBJID":"id-184","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.63913,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-04","TRTSDTM":"2019-05-04 08:19:47","TRTEDTM":"2022-02-15 03:30:55","TRT01SDTM":"2019-05-04 08:19:47","TRT01EDTM":"2021-02-14 21:30:55","TRT02SDTM":"2021-02-14 21:30:55","TRT02EDTM":"2022-02-15 03:30:55","AP01SDTM":"2019-05-04 08:19:47","AP01EDTM":"2021-02-14 21:30:55","AP02SDTM":"2021-02-14 21:30:55","AP02EDTM":"2022-02-15 03:30:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1018,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":1029,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":889,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.23567,"AVALU":"U/L","BASE2":17.40687,"BASE":22.82247,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1712,"PCHG2":-0.98352,"CHG":-5.58681,"PCHG":-24.47941,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-22 08:19:47","ADY":263,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-184","SUBJID":"id-184","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.63913,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-04","TRTSDTM":"2019-05-04 08:19:47","TRTEDTM":"2022-02-15 03:30:55","TRT01SDTM":"2019-05-04 08:19:47","TRT01EDTM":"2021-02-14 21:30:55","TRT02SDTM":"2021-02-14 21:30:55","TRT02EDTM":"2022-02-15 03:30:55","AP01SDTM":"2019-05-04 08:19:47","AP01EDTM":"2021-02-14 21:30:55","AP02SDTM":"2021-02-14 21:30:55","AP02EDTM":"2022-02-15 03:30:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1018,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":1029,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5781,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.10857,"AVALU":"U/L","BASE2":17.40687,"BASE":22.82247,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.29829,"PCHG2":-1.71365,"CHG":-5.7139,"PCHG":-25.03629,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-13 08:19:47","ADY":285,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-184","SUBJID":"id-184","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.63913,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-04","TRTSDTM":"2019-05-04 08:19:47","TRTEDTM":"2022-02-15 03:30:55","TRT01SDTM":"2019-05-04 08:19:47","TRT01EDTM":"2021-02-14 21:30:55","TRT02SDTM":"2021-02-14 21:30:55","TRT02EDTM":"2022-02-15 03:30:55","AP01SDTM":"2019-05-04 08:19:47","AP01EDTM":"2021-02-14 21:30:55","AP02SDTM":"2021-02-14 21:30:55","AP02EDTM":"2022-02-15 03:30:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1018,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":1029,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3684,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.21357,"AVALU":"U/L","BASE2":17.40687,"BASE":22.82247,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.19329,"PCHG2":-35.5796,"CHG":-11.6089,"PCHG":-50.86609,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-22 08:19:47","ADY":323,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-184","SUBJID":"id-184","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.63913,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-04","TRTSDTM":"2019-05-04 08:19:47","TRTEDTM":"2022-02-15 03:30:55","TRT01SDTM":"2019-05-04 08:19:47","TRT01EDTM":"2021-02-14 21:30:55","TRT02SDTM":"2021-02-14 21:30:55","TRT02EDTM":"2022-02-15 03:30:55","AP01SDTM":"2019-05-04 08:19:47","AP01EDTM":"2021-02-14 21:30:55","AP02SDTM":"2021-02-14 21:30:55","AP02EDTM":"2022-02-15 03:30:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1018,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":1029,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3909,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.24392,"AVALU":"U/L","BASE2":17.40687,"BASE":22.82247,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.16294,"PCHG2":-12.4258,"CHG":-7.57855,"PCHG":-33.20652,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-22 08:19:47","ADY":598,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-184","SUBJID":"id-184","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.63913,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-04","TRTSDTM":"2019-05-04 08:19:47","TRTEDTM":"2022-02-15 03:30:55","TRT01SDTM":"2019-05-04 08:19:47","TRT01EDTM":"2021-02-14 21:30:55","TRT02SDTM":"2021-02-14 21:30:55","TRT02EDTM":"2022-02-15 03:30:55","AP01SDTM":"2019-05-04 08:19:47","AP01EDTM":"2021-02-14 21:30:55","AP02SDTM":"2021-02-14 21:30:55","AP02EDTM":"2022-02-15 03:30:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1018,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":1029,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3370,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.19631,"AVALU":"U/L","BASE2":17.40687,"BASE":22.82247,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-15.21056,"PCHG2":-87.38253,"CHG":-20.62617,"PCHG":-90.37657,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-10-22 08:19:47","ADY":902,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-184","SUBJID":"id-184","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.63913,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-04","TRTSDTM":"2019-05-04 08:19:47","TRTEDTM":"2022-02-15 03:30:55","TRT01SDTM":"2019-05-04 08:19:47","TRT01EDTM":"2021-02-14 21:30:55","TRT02SDTM":"2021-02-14 21:30:55","TRT02EDTM":"2022-02-15 03:30:55","AP01SDTM":"2019-05-04 08:19:47","AP01EDTM":"2021-02-14 21:30:55","AP02SDTM":"2021-02-14 21:30:55","AP02EDTM":"2022-02-15 03:30:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1018,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":1029,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3155,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.83365,"AVALU":"mg/L","BASE2":9.83365,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-04 08:19:47","ADY":153,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-184","SUBJID":"id-184","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.63913,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-04","TRTSDTM":"2019-05-04 08:19:47","TRTEDTM":"2022-02-15 03:30:55","TRT01SDTM":"2019-05-04 08:19:47","TRT01EDTM":"2021-02-14 21:30:55","TRT02SDTM":"2021-02-14 21:30:55","TRT02EDTM":"2022-02-15 03:30:55","AP01SDTM":"2019-05-04 08:19:47","AP01EDTM":"2021-02-14 21:30:55","AP02SDTM":"2021-02-14 21:30:55","AP02EDTM":"2022-02-15 03:30:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1018,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":1029,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":16,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.58947,"AVALU":"mg/L","BASE2":9.83365,"BASE":8.58947,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.24418,"PCHG2":-12.65227,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-27 08:19:47","ADY":176,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-184","SUBJID":"id-184","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.63913,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-04","TRTSDTM":"2019-05-04 08:19:47","TRTEDTM":"2022-02-15 03:30:55","TRT01SDTM":"2019-05-04 08:19:47","TRT01EDTM":"2021-02-14 21:30:55","TRT02SDTM":"2021-02-14 21:30:55","TRT02EDTM":"2022-02-15 03:30:55","AP01SDTM":"2019-05-04 08:19:47","AP01EDTM":"2021-02-14 21:30:55","AP02SDTM":"2021-02-14 21:30:55","AP02EDTM":"2022-02-15 03:30:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1018,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":1029,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1129,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.80325,"AVALU":"mg/L","BASE2":9.83365,"BASE":8.58947,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.0304,"PCHG2":-20.64748,"CHG":-0.78622,"PCHG":-9.15331,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-01-22 08:19:47","ADY":263,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-184","SUBJID":"id-184","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.63913,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-04","TRTSDTM":"2019-05-04 08:19:47","TRTEDTM":"2022-02-15 03:30:55","TRT01SDTM":"2019-05-04 08:19:47","TRT01EDTM":"2021-02-14 21:30:55","TRT02SDTM":"2021-02-14 21:30:55","TRT02EDTM":"2022-02-15 03:30:55","AP01SDTM":"2019-05-04 08:19:47","AP01EDTM":"2021-02-14 21:30:55","AP02SDTM":"2021-02-14 21:30:55","AP02EDTM":"2022-02-15 03:30:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1018,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":1029,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3610,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.25839,"AVALU":"mg/L","BASE2":9.83365,"BASE":8.58947,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.57526,"PCHG2":-5.84987,"CHG":0.66892,"PCHG":7.78773,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-13 08:19:47","ADY":285,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-184","SUBJID":"id-184","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.63913,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-04","TRTSDTM":"2019-05-04 08:19:47","TRTEDTM":"2022-02-15 03:30:55","TRT01SDTM":"2019-05-04 08:19:47","TRT01EDTM":"2021-02-14 21:30:55","TRT02SDTM":"2021-02-14 21:30:55","TRT02EDTM":"2022-02-15 03:30:55","AP01SDTM":"2019-05-04 08:19:47","AP01EDTM":"2021-02-14 21:30:55","AP02SDTM":"2021-02-14 21:30:55","AP02EDTM":"2022-02-15 03:30:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1018,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":1029,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4401,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.19188,"AVALU":"mg/L","BASE2":9.83365,"BASE":8.58947,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.64177,"PCHG2":-16.69547,"CHG":-0.39759,"PCHG":-4.62885,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-22 08:19:47","ADY":323,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-184","SUBJID":"id-184","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.63913,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-04","TRTSDTM":"2019-05-04 08:19:47","TRTEDTM":"2022-02-15 03:30:55","TRT01SDTM":"2019-05-04 08:19:47","TRT01EDTM":"2021-02-14 21:30:55","TRT02SDTM":"2021-02-14 21:30:55","TRT02EDTM":"2022-02-15 03:30:55","AP01SDTM":"2019-05-04 08:19:47","AP01EDTM":"2021-02-14 21:30:55","AP02SDTM":"2021-02-14 21:30:55","AP02EDTM":"2022-02-15 03:30:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1018,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":1029,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5782,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.17979,"AVALU":"mg/L","BASE2":9.83365,"BASE":8.58947,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.34614,"PCHG2":3.52,"CHG":1.59032,"PCHG":18.51481,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-12-22 08:19:47","ADY":598,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-184","SUBJID":"id-184","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.63913,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-04","TRTSDTM":"2019-05-04 08:19:47","TRTEDTM":"2022-02-15 03:30:55","TRT01SDTM":"2019-05-04 08:19:47","TRT01EDTM":"2021-02-14 21:30:55","TRT02SDTM":"2021-02-14 21:30:55","TRT02EDTM":"2022-02-15 03:30:55","AP01SDTM":"2019-05-04 08:19:47","AP01EDTM":"2021-02-14 21:30:55","AP02SDTM":"2021-02-14 21:30:55","AP02EDTM":"2022-02-15 03:30:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1018,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":1029,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2419,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.28809,"AVALU":"mg/L","BASE2":9.83365,"BASE":8.58947,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.45444,"PCHG2":4.6213,"CHG":1.69862,"PCHG":19.77564,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-10-22 08:19:47","ADY":902,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-184","SUBJID":"id-184","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.63913,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-04","TRTSDTM":"2019-05-04 08:19:47","TRTEDTM":"2022-02-15 03:30:55","TRT01SDTM":"2019-05-04 08:19:47","TRT01EDTM":"2021-02-14 21:30:55","TRT02SDTM":"2021-02-14 21:30:55","TRT02EDTM":"2022-02-15 03:30:55","AP01SDTM":"2019-05-04 08:19:47","AP01EDTM":"2021-02-14 21:30:55","AP02SDTM":"2021-02-14 21:30:55","AP02EDTM":"2022-02-15 03:30:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1018,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":1029,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":390,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.71564,"AVALU":"g/L","BASE2":2.71564,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-04 08:19:47","ADY":153,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-184","SUBJID":"id-184","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.63913,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-04","TRTSDTM":"2019-05-04 08:19:47","TRTEDTM":"2022-02-15 03:30:55","TRT01SDTM":"2019-05-04 08:19:47","TRT01EDTM":"2021-02-14 21:30:55","TRT02SDTM":"2021-02-14 21:30:55","TRT02EDTM":"2022-02-15 03:30:55","AP01SDTM":"2019-05-04 08:19:47","AP01EDTM":"2021-02-14 21:30:55","AP02SDTM":"2021-02-14 21:30:55","AP02EDTM":"2022-02-15 03:30:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1018,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":1029,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1380,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91646,"AVALU":"g/L","BASE2":2.71564,"BASE":2.91646,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.20082,"PCHG2":7.39504,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-27 08:19:47","ADY":176,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-184","SUBJID":"id-184","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.63913,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-04","TRTSDTM":"2019-05-04 08:19:47","TRTEDTM":"2022-02-15 03:30:55","TRT01SDTM":"2019-05-04 08:19:47","TRT01EDTM":"2021-02-14 21:30:55","TRT02SDTM":"2021-02-14 21:30:55","TRT02EDTM":"2022-02-15 03:30:55","AP01SDTM":"2019-05-04 08:19:47","AP01EDTM":"2021-02-14 21:30:55","AP02SDTM":"2021-02-14 21:30:55","AP02EDTM":"2022-02-15 03:30:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1018,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":1029,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8012,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98828,"AVALU":"g/L","BASE2":2.71564,"BASE":2.91646,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.27264,"PCHG2":10.03977,"CHG":0.07182,"PCHG":2.46261,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-22 08:19:47","ADY":263,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-184","SUBJID":"id-184","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.63913,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-04","TRTSDTM":"2019-05-04 08:19:47","TRTEDTM":"2022-02-15 03:30:55","TRT01SDTM":"2019-05-04 08:19:47","TRT01EDTM":"2021-02-14 21:30:55","TRT02SDTM":"2021-02-14 21:30:55","TRT02EDTM":"2022-02-15 03:30:55","AP01SDTM":"2019-05-04 08:19:47","AP01EDTM":"2021-02-14 21:30:55","AP02SDTM":"2021-02-14 21:30:55","AP02EDTM":"2022-02-15 03:30:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1018,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":1029,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6747,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02978,"AVALU":"g/L","BASE2":2.71564,"BASE":2.91646,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.31414,"PCHG2":11.5677,"CHG":0.11331,"PCHG":3.88533,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-02-13 08:19:47","ADY":285,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-184","SUBJID":"id-184","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.63913,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-04","TRTSDTM":"2019-05-04 08:19:47","TRTEDTM":"2022-02-15 03:30:55","TRT01SDTM":"2019-05-04 08:19:47","TRT01EDTM":"2021-02-14 21:30:55","TRT02SDTM":"2021-02-14 21:30:55","TRT02EDTM":"2022-02-15 03:30:55","AP01SDTM":"2019-05-04 08:19:47","AP01EDTM":"2021-02-14 21:30:55","AP02SDTM":"2021-02-14 21:30:55","AP02EDTM":"2022-02-15 03:30:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1018,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":1029,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4257,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.18883,"AVALU":"g/L","BASE2":2.71564,"BASE":2.91646,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.47319,"PCHG2":17.42461,"CHG":0.27237,"PCHG":9.33895,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-03-22 08:19:47","ADY":323,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-184","SUBJID":"id-184","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.63913,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-04","TRTSDTM":"2019-05-04 08:19:47","TRTEDTM":"2022-02-15 03:30:55","TRT01SDTM":"2019-05-04 08:19:47","TRT01EDTM":"2021-02-14 21:30:55","TRT02SDTM":"2021-02-14 21:30:55","TRT02EDTM":"2022-02-15 03:30:55","AP01SDTM":"2019-05-04 08:19:47","AP01EDTM":"2021-02-14 21:30:55","AP02SDTM":"2021-02-14 21:30:55","AP02EDTM":"2022-02-15 03:30:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1018,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":1029,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5253,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.73501,"AVALU":"g/L","BASE2":2.71564,"BASE":2.91646,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01937,"PCHG2":0.71321,"CHG":-0.18145,"PCHG":-6.22174,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-22 08:19:47","ADY":598,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-184","SUBJID":"id-184","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.63913,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-04","TRTSDTM":"2019-05-04 08:19:47","TRTEDTM":"2022-02-15 03:30:55","TRT01SDTM":"2019-05-04 08:19:47","TRT01EDTM":"2021-02-14 21:30:55","TRT02SDTM":"2021-02-14 21:30:55","TRT02EDTM":"2022-02-15 03:30:55","AP01SDTM":"2019-05-04 08:19:47","AP01EDTM":"2021-02-14 21:30:55","AP02SDTM":"2021-02-14 21:30:55","AP02EDTM":"2022-02-15 03:30:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1018,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":1029,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7278,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.73733,"AVALU":"g/L","BASE2":2.71564,"BASE":2.91646,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02169,"PCHG2":0.79883,"CHG":-0.17913,"PCHG":-6.142,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-22 08:19:47","ADY":902,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-192","SUBJID":"id-192","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.76819,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-26 00:43:51","TRTEDTM":"2022-02-16 17:13:45","TRT01SDTM":"2019-12-26 00:43:51","TRT01EDTM":"2021-02-16 11:13:45","TRT02SDTM":"2021-02-16 11:13:45","TRT02EDTM":"2022-02-16 17:13:45","AP01SDTM":"2019-12-26 00:43:51","AP01EDTM":"2021-02-16 11:13:45","AP02SDTM":"2021-02-16 11:13:45","AP02EDTM":"2022-02-16 17:13:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":784,"DCSREAS":"DEATH","DTHDT":"2022-03-13","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-13","DTHADY":807,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2617,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.251,"AVALU":"U/L","BASE2":22.251,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-02 00:43:51","ADY":98,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-192","SUBJID":"id-192","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.76819,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-26 00:43:51","TRTEDTM":"2022-02-16 17:13:45","TRT01SDTM":"2019-12-26 00:43:51","TRT01EDTM":"2021-02-16 11:13:45","TRT02SDTM":"2021-02-16 11:13:45","TRT02EDTM":"2022-02-16 17:13:45","AP01SDTM":"2019-12-26 00:43:51","AP01EDTM":"2021-02-16 11:13:45","AP02SDTM":"2021-02-16 11:13:45","AP02EDTM":"2022-02-16 17:13:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":784,"DCSREAS":"DEATH","DTHDT":"2022-03-13","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-13","DTHADY":807,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1008,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.06554,"AVALU":"U/L","BASE2":22.251,"BASE":8.06554,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-14.18546,"PCHG2":-63.752,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-07 00:43:51","ADY":103,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-192","SUBJID":"id-192","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.76819,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-26 00:43:51","TRTEDTM":"2022-02-16 17:13:45","TRT01SDTM":"2019-12-26 00:43:51","TRT01EDTM":"2021-02-16 11:13:45","TRT02SDTM":"2021-02-16 11:13:45","TRT02EDTM":"2022-02-16 17:13:45","AP01SDTM":"2019-12-26 00:43:51","AP01EDTM":"2021-02-16 11:13:45","AP02SDTM":"2021-02-16 11:13:45","AP02EDTM":"2022-02-16 17:13:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":784,"DCSREAS":"DEATH","DTHDT":"2022-03-13","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-13","DTHADY":807,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7557,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.50238,"AVALU":"U/L","BASE2":22.251,"BASE":8.06554,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.74863,"PCHG2":-16.847,"CHG":10.43683,"PCHG":129.40022,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-10 00:43:51","ADY":106,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-192","SUBJID":"id-192","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.76819,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-26 00:43:51","TRTEDTM":"2022-02-16 17:13:45","TRT01SDTM":"2019-12-26 00:43:51","TRT01EDTM":"2021-02-16 11:13:45","TRT02SDTM":"2021-02-16 11:13:45","TRT02EDTM":"2022-02-16 17:13:45","AP01SDTM":"2019-12-26 00:43:51","AP01EDTM":"2021-02-16 11:13:45","AP02SDTM":"2021-02-16 11:13:45","AP02EDTM":"2022-02-16 17:13:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":784,"DCSREAS":"DEATH","DTHDT":"2022-03-13","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-13","DTHADY":807,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1584,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.64414,"AVALU":"U/L","BASE2":22.251,"BASE":8.06554,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.60686,"PCHG2":-7.22151,"CHG":12.5786,"PCHG":155.95474,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-17 00:43:51","ADY":447,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-192","SUBJID":"id-192","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.76819,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-26 00:43:51","TRTEDTM":"2022-02-16 17:13:45","TRT01SDTM":"2019-12-26 00:43:51","TRT01EDTM":"2021-02-16 11:13:45","TRT02SDTM":"2021-02-16 11:13:45","TRT02EDTM":"2022-02-16 17:13:45","AP01SDTM":"2019-12-26 00:43:51","AP01EDTM":"2021-02-16 11:13:45","AP02SDTM":"2021-02-16 11:13:45","AP02EDTM":"2022-02-16 17:13:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":784,"DCSREAS":"DEATH","DTHDT":"2022-03-13","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-13","DTHADY":807,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1257,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.78225,"AVALU":"U/L","BASE2":22.251,"BASE":8.06554,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.46876,"PCHG2":-29.07175,"CHG":7.7167,"PCHG":95.67491,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-01 00:43:51","ADY":462,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-192","SUBJID":"id-192","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.76819,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-26 00:43:51","TRTEDTM":"2022-02-16 17:13:45","TRT01SDTM":"2019-12-26 00:43:51","TRT01EDTM":"2021-02-16 11:13:45","TRT02SDTM":"2021-02-16 11:13:45","TRT02EDTM":"2022-02-16 17:13:45","AP01SDTM":"2019-12-26 00:43:51","AP01EDTM":"2021-02-16 11:13:45","AP02SDTM":"2021-02-16 11:13:45","AP02EDTM":"2022-02-16 17:13:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":784,"DCSREAS":"DEATH","DTHDT":"2022-03-13","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-13","DTHADY":807,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5821,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.06886,"AVALU":"U/L","BASE2":22.251,"BASE":8.06554,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.18215,"PCHG2":-5.31278,"CHG":13.00331,"PCHG":161.22051,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-06 00:43:51","ADY":773,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-192","SUBJID":"id-192","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.76819,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-26 00:43:51","TRTEDTM":"2022-02-16 17:13:45","TRT01SDTM":"2019-12-26 00:43:51","TRT01EDTM":"2021-02-16 11:13:45","TRT02SDTM":"2021-02-16 11:13:45","TRT02EDTM":"2022-02-16 17:13:45","AP01SDTM":"2019-12-26 00:43:51","AP01EDTM":"2021-02-16 11:13:45","AP02SDTM":"2021-02-16 11:13:45","AP02EDTM":"2022-02-16 17:13:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":784,"DCSREAS":"DEATH","DTHDT":"2022-03-13","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-13","DTHADY":807,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5896,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.02192,"AVALU":"U/L","BASE2":22.251,"BASE":8.06554,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.22909,"PCHG2":-54.95971,"CHG":1.95637,"PCHG":24.25593,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-07 00:43:51","ADY":774,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-192","SUBJID":"id-192","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.76819,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-26 00:43:51","TRTEDTM":"2022-02-16 17:13:45","TRT01SDTM":"2019-12-26 00:43:51","TRT01EDTM":"2021-02-16 11:13:45","TRT02SDTM":"2021-02-16 11:13:45","TRT02EDTM":"2022-02-16 17:13:45","AP01SDTM":"2019-12-26 00:43:51","AP01EDTM":"2021-02-16 11:13:45","AP02SDTM":"2021-02-16 11:13:45","AP02EDTM":"2022-02-16 17:13:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":784,"DCSREAS":"DEATH","DTHDT":"2022-03-13","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-13","DTHADY":807,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3694,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.11197,"AVALU":"mg/L","BASE2":9.11197,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-02 00:43:51","ADY":98,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-192","SUBJID":"id-192","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.76819,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-26 00:43:51","TRTEDTM":"2022-02-16 17:13:45","TRT01SDTM":"2019-12-26 00:43:51","TRT01EDTM":"2021-02-16 11:13:45","TRT02SDTM":"2021-02-16 11:13:45","TRT02EDTM":"2022-02-16 17:13:45","AP01SDTM":"2019-12-26 00:43:51","AP01EDTM":"2021-02-16 11:13:45","AP02SDTM":"2021-02-16 11:13:45","AP02EDTM":"2022-02-16 17:13:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":784,"DCSREAS":"DEATH","DTHDT":"2022-03-13","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-13","DTHADY":807,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6749,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.66014,"AVALU":"mg/L","BASE2":9.11197,"BASE":8.66014,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.45183,"PCHG2":-4.95865,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-07 00:43:51","ADY":103,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-192","SUBJID":"id-192","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.76819,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-26 00:43:51","TRTEDTM":"2022-02-16 17:13:45","TRT01SDTM":"2019-12-26 00:43:51","TRT01EDTM":"2021-02-16 11:13:45","TRT02SDTM":"2021-02-16 11:13:45","TRT02EDTM":"2022-02-16 17:13:45","AP01SDTM":"2019-12-26 00:43:51","AP01EDTM":"2021-02-16 11:13:45","AP02SDTM":"2021-02-16 11:13:45","AP02EDTM":"2022-02-16 17:13:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":784,"DCSREAS":"DEATH","DTHDT":"2022-03-13","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-13","DTHADY":807,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5405,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.72407,"AVALU":"mg/L","BASE2":9.11197,"BASE":8.66014,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.6121,"PCHG2":6.71755,"CHG":1.06393,"PCHG":12.28539,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-10 00:43:51","ADY":106,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-192","SUBJID":"id-192","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.76819,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-26 00:43:51","TRTEDTM":"2022-02-16 17:13:45","TRT01SDTM":"2019-12-26 00:43:51","TRT01EDTM":"2021-02-16 11:13:45","TRT02SDTM":"2021-02-16 11:13:45","TRT02EDTM":"2022-02-16 17:13:45","AP01SDTM":"2019-12-26 00:43:51","AP01EDTM":"2021-02-16 11:13:45","AP02SDTM":"2021-02-16 11:13:45","AP02EDTM":"2022-02-16 17:13:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":784,"DCSREAS":"DEATH","DTHDT":"2022-03-13","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-13","DTHADY":807,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":47,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.39994,"AVALU":"mg/L","BASE2":9.11197,"BASE":8.66014,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.71203,"PCHG2":-18.78879,"CHG":-1.2602,"PCHG":-14.55171,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-03-17 00:43:51","ADY":447,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-192","SUBJID":"id-192","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.76819,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-26 00:43:51","TRTEDTM":"2022-02-16 17:13:45","TRT01SDTM":"2019-12-26 00:43:51","TRT01EDTM":"2021-02-16 11:13:45","TRT02SDTM":"2021-02-16 11:13:45","TRT02EDTM":"2022-02-16 17:13:45","AP01SDTM":"2019-12-26 00:43:51","AP01EDTM":"2021-02-16 11:13:45","AP02SDTM":"2021-02-16 11:13:45","AP02EDTM":"2022-02-16 17:13:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":784,"DCSREAS":"DEATH","DTHDT":"2022-03-13","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-13","DTHADY":807,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7062,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.98681,"AVALU":"mg/L","BASE2":9.11197,"BASE":8.66014,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12516,"PCHG2":-1.37356,"CHG":0.32667,"PCHG":3.77214,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-01 00:43:51","ADY":462,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-192","SUBJID":"id-192","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.76819,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-26 00:43:51","TRTEDTM":"2022-02-16 17:13:45","TRT01SDTM":"2019-12-26 00:43:51","TRT01EDTM":"2021-02-16 11:13:45","TRT02SDTM":"2021-02-16 11:13:45","TRT02EDTM":"2022-02-16 17:13:45","AP01SDTM":"2019-12-26 00:43:51","AP01EDTM":"2021-02-16 11:13:45","AP02SDTM":"2021-02-16 11:13:45","AP02EDTM":"2022-02-16 17:13:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":784,"DCSREAS":"DEATH","DTHDT":"2022-03-13","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-13","DTHADY":807,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4263,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.79884,"AVALU":"mg/L","BASE2":9.11197,"BASE":8.66014,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.31313,"PCHG2":-3.43643,"CHG":0.1387,"PCHG":1.60164,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-06 00:43:51","ADY":773,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-192","SUBJID":"id-192","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.76819,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-26 00:43:51","TRTEDTM":"2022-02-16 17:13:45","TRT01SDTM":"2019-12-26 00:43:51","TRT01EDTM":"2021-02-16 11:13:45","TRT02SDTM":"2021-02-16 11:13:45","TRT02EDTM":"2022-02-16 17:13:45","AP01SDTM":"2019-12-26 00:43:51","AP01EDTM":"2021-02-16 11:13:45","AP02SDTM":"2021-02-16 11:13:45","AP02EDTM":"2022-02-16 17:13:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":784,"DCSREAS":"DEATH","DTHDT":"2022-03-13","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-13","DTHADY":807,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6585,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.50586,"AVALU":"mg/L","BASE2":9.11197,"BASE":8.66014,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.39389,"PCHG2":4.32282,"CHG":0.84572,"PCHG":9.76572,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-07 00:43:51","ADY":774,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-192","SUBJID":"id-192","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.76819,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-26 00:43:51","TRTEDTM":"2022-02-16 17:13:45","TRT01SDTM":"2019-12-26 00:43:51","TRT01EDTM":"2021-02-16 11:13:45","TRT02SDTM":"2021-02-16 11:13:45","TRT02EDTM":"2022-02-16 17:13:45","AP01SDTM":"2019-12-26 00:43:51","AP01EDTM":"2021-02-16 11:13:45","AP02SDTM":"2021-02-16 11:13:45","AP02EDTM":"2022-02-16 17:13:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":784,"DCSREAS":"DEATH","DTHDT":"2022-03-13","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-13","DTHADY":807,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7982,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99777,"AVALU":"g/L","BASE2":2.99777,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-02 00:43:51","ADY":98,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-192","SUBJID":"id-192","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.76819,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-26 00:43:51","TRTEDTM":"2022-02-16 17:13:45","TRT01SDTM":"2019-12-26 00:43:51","TRT01EDTM":"2021-02-16 11:13:45","TRT02SDTM":"2021-02-16 11:13:45","TRT02EDTM":"2022-02-16 17:13:45","AP01SDTM":"2019-12-26 00:43:51","AP01EDTM":"2021-02-16 11:13:45","AP02SDTM":"2021-02-16 11:13:45","AP02EDTM":"2022-02-16 17:13:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":784,"DCSREAS":"DEATH","DTHDT":"2022-03-13","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-13","DTHADY":807,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8087,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92034,"AVALU":"g/L","BASE2":2.99777,"BASE":2.92034,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.07743,"PCHG2":-2.5829,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-07 00:43:51","ADY":103,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-192","SUBJID":"id-192","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.76819,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-26 00:43:51","TRTEDTM":"2022-02-16 17:13:45","TRT01SDTM":"2019-12-26 00:43:51","TRT01EDTM":"2021-02-16 11:13:45","TRT02SDTM":"2021-02-16 11:13:45","TRT02EDTM":"2022-02-16 17:13:45","AP01SDTM":"2019-12-26 00:43:51","AP01EDTM":"2021-02-16 11:13:45","AP02SDTM":"2021-02-16 11:13:45","AP02EDTM":"2022-02-16 17:13:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":784,"DCSREAS":"DEATH","DTHDT":"2022-03-13","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-13","DTHADY":807,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3017,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99701,"AVALU":"g/L","BASE2":2.99777,"BASE":2.92034,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00076,"PCHG2":-0.02536,"CHG":0.07667,"PCHG":2.62534,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-10 00:43:51","ADY":106,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-192","SUBJID":"id-192","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.76819,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-26 00:43:51","TRTEDTM":"2022-02-16 17:13:45","TRT01SDTM":"2019-12-26 00:43:51","TRT01EDTM":"2021-02-16 11:13:45","TRT02SDTM":"2021-02-16 11:13:45","TRT02EDTM":"2022-02-16 17:13:45","AP01SDTM":"2019-12-26 00:43:51","AP01EDTM":"2021-02-16 11:13:45","AP02SDTM":"2021-02-16 11:13:45","AP02EDTM":"2022-02-16 17:13:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":784,"DCSREAS":"DEATH","DTHDT":"2022-03-13","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-13","DTHADY":807,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":575,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85194,"AVALU":"g/L","BASE2":2.99777,"BASE":2.92034,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14583,"PCHG2":-4.86461,"CHG":-0.0684,"PCHG":-2.34222,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-17 00:43:51","ADY":447,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-192","SUBJID":"id-192","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.76819,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-26 00:43:51","TRTEDTM":"2022-02-16 17:13:45","TRT01SDTM":"2019-12-26 00:43:51","TRT01EDTM":"2021-02-16 11:13:45","TRT02SDTM":"2021-02-16 11:13:45","TRT02EDTM":"2022-02-16 17:13:45","AP01SDTM":"2019-12-26 00:43:51","AP01EDTM":"2021-02-16 11:13:45","AP02SDTM":"2021-02-16 11:13:45","AP02EDTM":"2022-02-16 17:13:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":784,"DCSREAS":"DEATH","DTHDT":"2022-03-13","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-13","DTHADY":807,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8177,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98284,"AVALU":"g/L","BASE2":2.99777,"BASE":2.92034,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01493,"PCHG2":-0.49809,"CHG":0.0625,"PCHG":2.14009,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-01 00:43:51","ADY":462,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-192","SUBJID":"id-192","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.76819,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-26 00:43:51","TRTEDTM":"2022-02-16 17:13:45","TRT01SDTM":"2019-12-26 00:43:51","TRT01EDTM":"2021-02-16 11:13:45","TRT02SDTM":"2021-02-16 11:13:45","TRT02EDTM":"2022-02-16 17:13:45","AP01SDTM":"2019-12-26 00:43:51","AP01EDTM":"2021-02-16 11:13:45","AP02SDTM":"2021-02-16 11:13:45","AP02EDTM":"2022-02-16 17:13:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":784,"DCSREAS":"DEATH","DTHDT":"2022-03-13","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-13","DTHADY":807,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2371,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8004,"AVALU":"g/L","BASE2":2.99777,"BASE":2.92034,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19736,"PCHG2":-6.58369,"CHG":-0.11993,"PCHG":-4.10687,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-06 00:43:51","ADY":773,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-192","SUBJID":"id-192","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.76819,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-26 00:43:51","TRTEDTM":"2022-02-16 17:13:45","TRT01SDTM":"2019-12-26 00:43:51","TRT01EDTM":"2021-02-16 11:13:45","TRT02SDTM":"2021-02-16 11:13:45","TRT02EDTM":"2022-02-16 17:13:45","AP01SDTM":"2019-12-26 00:43:51","AP01EDTM":"2021-02-16 11:13:45","AP02SDTM":"2021-02-16 11:13:45","AP02EDTM":"2022-02-16 17:13:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":784,"DCSREAS":"DEATH","DTHDT":"2022-03-13","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-13","DTHADY":807,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":286,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93813,"AVALU":"g/L","BASE2":2.99777,"BASE":2.92034,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05964,"PCHG2":-1.98937,"CHG":0.01779,"PCHG":0.60927,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-07 00:43:51","ADY":774,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-2","SUBJID":"id-2","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.01534,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-09","TRTSDTM":"2020-07-13 04:42:18","TRTEDTM":"2023-07-13 22:42:18","TRT01SDTM":"2020-07-13 04:42:18","TRT01EDTM":"2022-07-13 16:42:18","TRT02SDTM":"2022-07-13 16:42:18","TRT02EDTM":"2023-07-13 22:42:18","AP01SDTM":"2020-07-13 04:42:18","AP01EDTM":"2022-07-13 16:42:18","AP02SDTM":"2022-07-13 16:42:18","AP02EDTM":"2023-07-13 22:42:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-13","EOSDY":1096,"LSTALVDT":"2023-07-25","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8310,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.83755,"AVALU":"U/L","BASE2":4.83755,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-09-14 04:42:18","ADY":63,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-2","SUBJID":"id-2","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.01534,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-09","TRTSDTM":"2020-07-13 04:42:18","TRTEDTM":"2023-07-13 22:42:18","TRT01SDTM":"2020-07-13 04:42:18","TRT01EDTM":"2022-07-13 16:42:18","TRT02SDTM":"2022-07-13 16:42:18","TRT02EDTM":"2023-07-13 22:42:18","AP01SDTM":"2020-07-13 04:42:18","AP01EDTM":"2022-07-13 16:42:18","AP02SDTM":"2022-07-13 16:42:18","AP02EDTM":"2023-07-13 22:42:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-13","EOSDY":1096,"LSTALVDT":"2023-07-25","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4911,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.62007,"AVALU":"U/L","BASE2":4.83755,"BASE":8.62007,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":3.78253,"PCHG2":78.19098,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-14 04:42:18","ADY":397,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-2","SUBJID":"id-2","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.01534,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-09","TRTSDTM":"2020-07-13 04:42:18","TRTEDTM":"2023-07-13 22:42:18","TRT01SDTM":"2020-07-13 04:42:18","TRT01EDTM":"2022-07-13 16:42:18","TRT02SDTM":"2022-07-13 16:42:18","TRT02EDTM":"2023-07-13 22:42:18","AP01SDTM":"2020-07-13 04:42:18","AP01EDTM":"2022-07-13 16:42:18","AP02SDTM":"2022-07-13 16:42:18","AP02EDTM":"2023-07-13 22:42:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-13","EOSDY":1096,"LSTALVDT":"2023-07-25","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8011,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":35.1796,"AVALU":"U/L","BASE2":4.83755,"BASE":8.62007,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":30.34205,"PCHG2":627.21955,"CHG":26.55952,"PCHG":308.11245,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-26 04:42:18","ADY":562,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-2","SUBJID":"id-2","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.01534,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-09","TRTSDTM":"2020-07-13 04:42:18","TRTEDTM":"2023-07-13 22:42:18","TRT01SDTM":"2020-07-13 04:42:18","TRT01EDTM":"2022-07-13 16:42:18","TRT02SDTM":"2022-07-13 16:42:18","TRT02EDTM":"2023-07-13 22:42:18","AP01SDTM":"2020-07-13 04:42:18","AP01EDTM":"2022-07-13 16:42:18","AP02SDTM":"2022-07-13 16:42:18","AP02EDTM":"2023-07-13 22:42:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-13","EOSDY":1096,"LSTALVDT":"2023-07-25","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":578,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.72297,"AVALU":"U/L","BASE2":4.83755,"BASE":8.62007,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.88542,"PCHG2":142.33283,"CHG":3.10289,"PCHG":35.99613,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-12 04:42:18","ADY":760,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-2","SUBJID":"id-2","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.01534,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-09","TRTSDTM":"2020-07-13 04:42:18","TRTEDTM":"2023-07-13 22:42:18","TRT01SDTM":"2020-07-13 04:42:18","TRT01EDTM":"2022-07-13 16:42:18","TRT02SDTM":"2022-07-13 16:42:18","TRT02EDTM":"2023-07-13 22:42:18","AP01SDTM":"2020-07-13 04:42:18","AP01EDTM":"2022-07-13 16:42:18","AP02SDTM":"2022-07-13 16:42:18","AP02EDTM":"2023-07-13 22:42:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-13","EOSDY":1096,"LSTALVDT":"2023-07-25","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7336,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.85619,"AVALU":"U/L","BASE2":4.83755,"BASE":8.62007,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.01865,"PCHG2":186.43008,"CHG":5.23612,"PCHG":60.74332,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-19 04:42:18","ADY":767,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-2","SUBJID":"id-2","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.01534,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-09","TRTSDTM":"2020-07-13 04:42:18","TRTEDTM":"2023-07-13 22:42:18","TRT01SDTM":"2020-07-13 04:42:18","TRT01EDTM":"2022-07-13 16:42:18","TRT02SDTM":"2022-07-13 16:42:18","TRT02EDTM":"2023-07-13 22:42:18","AP01SDTM":"2020-07-13 04:42:18","AP01EDTM":"2022-07-13 16:42:18","AP02SDTM":"2022-07-13 16:42:18","AP02EDTM":"2023-07-13 22:42:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-13","EOSDY":1096,"LSTALVDT":"2023-07-25","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2350,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.33916,"AVALU":"U/L","BASE2":4.83755,"BASE":8.62007,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.50161,"PCHG2":134.39886,"CHG":2.71908,"PCHG":31.54362,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-11 04:42:18","ADY":790,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-2","SUBJID":"id-2","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.01534,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-09","TRTSDTM":"2020-07-13 04:42:18","TRTEDTM":"2023-07-13 22:42:18","TRT01SDTM":"2020-07-13 04:42:18","TRT01EDTM":"2022-07-13 16:42:18","TRT02SDTM":"2022-07-13 16:42:18","TRT02EDTM":"2023-07-13 22:42:18","AP01SDTM":"2020-07-13 04:42:18","AP01EDTM":"2022-07-13 16:42:18","AP02SDTM":"2022-07-13 16:42:18","AP02EDTM":"2023-07-13 22:42:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-13","EOSDY":1096,"LSTALVDT":"2023-07-25","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":667,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.86518,"AVALU":"U/L","BASE2":4.83755,"BASE":8.62007,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.02763,"PCHG2":207.28753,"CHG":6.24511,"PCHG":72.44843,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-15 04:42:18","ADY":916,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-2","SUBJID":"id-2","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.01534,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-09","TRTSDTM":"2020-07-13 04:42:18","TRTEDTM":"2023-07-13 22:42:18","TRT01SDTM":"2020-07-13 04:42:18","TRT01EDTM":"2022-07-13 16:42:18","TRT02SDTM":"2022-07-13 16:42:18","TRT02EDTM":"2023-07-13 22:42:18","AP01SDTM":"2020-07-13 04:42:18","AP01EDTM":"2022-07-13 16:42:18","AP02SDTM":"2022-07-13 16:42:18","AP02EDTM":"2023-07-13 22:42:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-13","EOSDY":1096,"LSTALVDT":"2023-07-25","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4250,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.34821,"AVALU":"mg/L","BASE2":10.34821,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-09-14 04:42:18","ADY":63,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-2","SUBJID":"id-2","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.01534,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-09","TRTSDTM":"2020-07-13 04:42:18","TRTEDTM":"2023-07-13 22:42:18","TRT01SDTM":"2020-07-13 04:42:18","TRT01EDTM":"2022-07-13 16:42:18","TRT02SDTM":"2022-07-13 16:42:18","TRT02EDTM":"2023-07-13 22:42:18","AP01SDTM":"2020-07-13 04:42:18","AP01EDTM":"2022-07-13 16:42:18","AP02SDTM":"2022-07-13 16:42:18","AP02EDTM":"2023-07-13 22:42:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-13","EOSDY":1096,"LSTALVDT":"2023-07-25","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":250,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.87183,"AVALU":"mg/L","BASE2":10.34821,"BASE":8.87183,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.47638,"PCHG2":-14.26705,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-14 04:42:18","ADY":397,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-2","SUBJID":"id-2","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.01534,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-09","TRTSDTM":"2020-07-13 04:42:18","TRTEDTM":"2023-07-13 22:42:18","TRT01SDTM":"2020-07-13 04:42:18","TRT01EDTM":"2022-07-13 16:42:18","TRT02SDTM":"2022-07-13 16:42:18","TRT02EDTM":"2023-07-13 22:42:18","AP01SDTM":"2020-07-13 04:42:18","AP01EDTM":"2022-07-13 16:42:18","AP02SDTM":"2022-07-13 16:42:18","AP02EDTM":"2023-07-13 22:42:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-13","EOSDY":1096,"LSTALVDT":"2023-07-25","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":913,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.96573,"AVALU":"mg/L","BASE2":10.34821,"BASE":8.87183,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.38248,"PCHG2":-3.6961,"CHG":1.0939,"PCHG":12.33008,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-26 04:42:18","ADY":562,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-2","SUBJID":"id-2","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.01534,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-09","TRTSDTM":"2020-07-13 04:42:18","TRTEDTM":"2023-07-13 22:42:18","TRT01SDTM":"2020-07-13 04:42:18","TRT01EDTM":"2022-07-13 16:42:18","TRT02SDTM":"2022-07-13 16:42:18","TRT02EDTM":"2023-07-13 22:42:18","AP01SDTM":"2020-07-13 04:42:18","AP01EDTM":"2022-07-13 16:42:18","AP02SDTM":"2022-07-13 16:42:18","AP02EDTM":"2023-07-13 22:42:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-13","EOSDY":1096,"LSTALVDT":"2023-07-25","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4756,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.36239,"AVALU":"mg/L","BASE2":10.34821,"BASE":8.87183,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.98582,"PCHG2":-9.52652,"CHG":0.49056,"PCHG":5.52941,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-12 04:42:18","ADY":760,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-2","SUBJID":"id-2","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.01534,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-09","TRTSDTM":"2020-07-13 04:42:18","TRTEDTM":"2023-07-13 22:42:18","TRT01SDTM":"2020-07-13 04:42:18","TRT01EDTM":"2022-07-13 16:42:18","TRT02SDTM":"2022-07-13 16:42:18","TRT02EDTM":"2023-07-13 22:42:18","AP01SDTM":"2020-07-13 04:42:18","AP01EDTM":"2022-07-13 16:42:18","AP02SDTM":"2022-07-13 16:42:18","AP02EDTM":"2023-07-13 22:42:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-13","EOSDY":1096,"LSTALVDT":"2023-07-25","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2874,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.10526,"AVALU":"mg/L","BASE2":10.34821,"BASE":8.87183,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.24295,"PCHG2":-2.34778,"CHG":1.23343,"PCHG":13.90278,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-08-19 04:42:18","ADY":767,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-2","SUBJID":"id-2","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.01534,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-09","TRTSDTM":"2020-07-13 04:42:18","TRTEDTM":"2023-07-13 22:42:18","TRT01SDTM":"2020-07-13 04:42:18","TRT01EDTM":"2022-07-13 16:42:18","TRT02SDTM":"2022-07-13 16:42:18","TRT02EDTM":"2023-07-13 22:42:18","AP01SDTM":"2020-07-13 04:42:18","AP01EDTM":"2022-07-13 16:42:18","AP02SDTM":"2022-07-13 16:42:18","AP02EDTM":"2023-07-13 22:42:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-13","EOSDY":1096,"LSTALVDT":"2023-07-25","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1411,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.49046,"AVALU":"mg/L","BASE2":10.34821,"BASE":8.87183,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.85775,"PCHG2":-17.95238,"CHG":-0.38137,"PCHG":-4.29862,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-11 04:42:18","ADY":790,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-2","SUBJID":"id-2","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.01534,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-09","TRTSDTM":"2020-07-13 04:42:18","TRTEDTM":"2023-07-13 22:42:18","TRT01SDTM":"2020-07-13 04:42:18","TRT01EDTM":"2022-07-13 16:42:18","TRT02SDTM":"2022-07-13 16:42:18","TRT02EDTM":"2023-07-13 22:42:18","AP01SDTM":"2020-07-13 04:42:18","AP01EDTM":"2022-07-13 16:42:18","AP02SDTM":"2022-07-13 16:42:18","AP02EDTM":"2023-07-13 22:42:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-13","EOSDY":1096,"LSTALVDT":"2023-07-25","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2215,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.12937,"AVALU":"mg/L","BASE2":10.34821,"BASE":8.87183,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21884,"PCHG2":-2.11479,"CHG":1.25754,"PCHG":14.17455,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2023-01-15 04:42:18","ADY":916,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-2","SUBJID":"id-2","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.01534,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-09","TRTSDTM":"2020-07-13 04:42:18","TRTEDTM":"2023-07-13 22:42:18","TRT01SDTM":"2020-07-13 04:42:18","TRT01EDTM":"2022-07-13 16:42:18","TRT02SDTM":"2022-07-13 16:42:18","TRT02EDTM":"2023-07-13 22:42:18","AP01SDTM":"2020-07-13 04:42:18","AP01EDTM":"2022-07-13 16:42:18","AP02SDTM":"2022-07-13 16:42:18","AP02EDTM":"2023-07-13 22:42:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-13","EOSDY":1096,"LSTALVDT":"2023-07-25","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7595,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89972,"AVALU":"g/L","BASE2":2.89972,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-14 04:42:18","ADY":63,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-2","SUBJID":"id-2","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.01534,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-09","TRTSDTM":"2020-07-13 04:42:18","TRTEDTM":"2023-07-13 22:42:18","TRT01SDTM":"2020-07-13 04:42:18","TRT01EDTM":"2022-07-13 16:42:18","TRT02SDTM":"2022-07-13 16:42:18","TRT02EDTM":"2023-07-13 22:42:18","AP01SDTM":"2020-07-13 04:42:18","AP01EDTM":"2022-07-13 16:42:18","AP02SDTM":"2022-07-13 16:42:18","AP02EDTM":"2023-07-13 22:42:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-13","EOSDY":1096,"LSTALVDT":"2023-07-25","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6302,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76999,"AVALU":"g/L","BASE2":2.89972,"BASE":2.76999,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.12973,"PCHG2":-4.47381,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-14 04:42:18","ADY":397,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-2","SUBJID":"id-2","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.01534,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-09","TRTSDTM":"2020-07-13 04:42:18","TRTEDTM":"2023-07-13 22:42:18","TRT01SDTM":"2020-07-13 04:42:18","TRT01EDTM":"2022-07-13 16:42:18","TRT02SDTM":"2022-07-13 16:42:18","TRT02EDTM":"2023-07-13 22:42:18","AP01SDTM":"2020-07-13 04:42:18","AP01EDTM":"2022-07-13 16:42:18","AP02SDTM":"2022-07-13 16:42:18","AP02EDTM":"2023-07-13 22:42:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-13","EOSDY":1096,"LSTALVDT":"2023-07-25","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":518,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03887,"AVALU":"g/L","BASE2":2.89972,"BASE":2.76999,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13916,"PCHG2":4.79894,"CHG":0.26888,"PCHG":9.70703,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-01-26 04:42:18","ADY":562,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-2","SUBJID":"id-2","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.01534,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-09","TRTSDTM":"2020-07-13 04:42:18","TRTEDTM":"2023-07-13 22:42:18","TRT01SDTM":"2020-07-13 04:42:18","TRT01EDTM":"2022-07-13 16:42:18","TRT02SDTM":"2022-07-13 16:42:18","TRT02EDTM":"2023-07-13 22:42:18","AP01SDTM":"2020-07-13 04:42:18","AP01EDTM":"2022-07-13 16:42:18","AP02SDTM":"2022-07-13 16:42:18","AP02EDTM":"2023-07-13 22:42:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-13","EOSDY":1096,"LSTALVDT":"2023-07-25","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3592,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02129,"AVALU":"g/L","BASE2":2.89972,"BASE":2.76999,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12157,"PCHG2":4.19257,"CHG":0.2513,"PCHG":9.07225,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-08-12 04:42:18","ADY":760,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-2","SUBJID":"id-2","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.01534,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-09","TRTSDTM":"2020-07-13 04:42:18","TRTEDTM":"2023-07-13 22:42:18","TRT01SDTM":"2020-07-13 04:42:18","TRT01EDTM":"2022-07-13 16:42:18","TRT02SDTM":"2022-07-13 16:42:18","TRT02EDTM":"2023-07-13 22:42:18","AP01SDTM":"2020-07-13 04:42:18","AP01EDTM":"2022-07-13 16:42:18","AP02SDTM":"2022-07-13 16:42:18","AP02EDTM":"2023-07-13 22:42:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-13","EOSDY":1096,"LSTALVDT":"2023-07-25","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2554,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96551,"AVALU":"g/L","BASE2":2.89972,"BASE":2.76999,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06579,"PCHG2":2.26897,"CHG":0.19552,"PCHG":7.05857,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-19 04:42:18","ADY":767,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-2","SUBJID":"id-2","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.01534,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-09","TRTSDTM":"2020-07-13 04:42:18","TRTEDTM":"2023-07-13 22:42:18","TRT01SDTM":"2020-07-13 04:42:18","TRT01EDTM":"2022-07-13 16:42:18","TRT02SDTM":"2022-07-13 16:42:18","TRT02EDTM":"2023-07-13 22:42:18","AP01SDTM":"2020-07-13 04:42:18","AP01EDTM":"2022-07-13 16:42:18","AP02SDTM":"2022-07-13 16:42:18","AP02EDTM":"2023-07-13 22:42:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-13","EOSDY":1096,"LSTALVDT":"2023-07-25","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4089,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80121,"AVALU":"g/L","BASE2":2.89972,"BASE":2.76999,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0985,"PCHG2":-3.39702,"CHG":0.03122,"PCHG":1.12721,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-11 04:42:18","ADY":790,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-2","SUBJID":"id-2","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.01534,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-09","TRTSDTM":"2020-07-13 04:42:18","TRTEDTM":"2023-07-13 22:42:18","TRT01SDTM":"2020-07-13 04:42:18","TRT01EDTM":"2022-07-13 16:42:18","TRT02SDTM":"2022-07-13 16:42:18","TRT02EDTM":"2023-07-13 22:42:18","AP01SDTM":"2020-07-13 04:42:18","AP01EDTM":"2022-07-13 16:42:18","AP02SDTM":"2022-07-13 16:42:18","AP02EDTM":"2023-07-13 22:42:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-13","EOSDY":1096,"LSTALVDT":"2023-07-25","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3808,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.69835,"AVALU":"g/L","BASE2":2.89972,"BASE":2.76999,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20137,"PCHG2":-6.94452,"CHG":-0.07164,"PCHG":-2.58643,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-15 04:42:18","ADY":916,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-220","SUBJID":"id-220","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.26273,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-27","TRTSDTM":"2019-03-01 13:33:19","TRTEDTM":"2022-03-01 07:33:19","TRT01SDTM":"2019-03-01 13:33:19","TRT01EDTM":"2021-03-01 01:33:19","TRT02SDTM":"2021-03-01 01:33:19","TRT02EDTM":"2022-03-01 07:33:19","AP01SDTM":"2019-03-01 13:33:19","AP01EDTM":"2021-03-01 01:33:19","AP02SDTM":"2021-03-01 01:33:19","AP02EDTM":"2022-03-01 07:33:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-26","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5779,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.95281,"AVALU":"U/L","BASE2":33.95281,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-1","ADTM":"2019-04-23 13:33:19","ADY":53,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-220","SUBJID":"id-220","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.26273,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-27","TRTSDTM":"2019-03-01 13:33:19","TRTEDTM":"2022-03-01 07:33:19","TRT01SDTM":"2019-03-01 13:33:19","TRT01EDTM":"2021-03-01 01:33:19","TRT02SDTM":"2021-03-01 01:33:19","TRT02EDTM":"2022-03-01 07:33:19","AP01SDTM":"2019-03-01 13:33:19","AP01EDTM":"2021-03-01 01:33:19","AP02SDTM":"2021-03-01 01:33:19","AP02EDTM":"2022-03-01 07:33:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-26","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3338,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.06118,"AVALU":"U/L","BASE2":33.95281,"BASE":3.06118,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-30.89162,"PCHG2":-90.984,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2020-03-05 13:33:19","ADY":370,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-220","SUBJID":"id-220","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.26273,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-27","TRTSDTM":"2019-03-01 13:33:19","TRTEDTM":"2022-03-01 07:33:19","TRT01SDTM":"2019-03-01 13:33:19","TRT01EDTM":"2021-03-01 01:33:19","TRT02SDTM":"2021-03-01 01:33:19","TRT02EDTM":"2022-03-01 07:33:19","AP01SDTM":"2019-03-01 13:33:19","AP01EDTM":"2021-03-01 01:33:19","AP02SDTM":"2021-03-01 01:33:19","AP02EDTM":"2022-03-01 07:33:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-26","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2297,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.82944,"AVALU":"U/L","BASE2":33.95281,"BASE":3.06118,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.12337,"PCHG2":-3.30862,"CHG":29.76825,"PCHG":972.44234,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-08-18 13:33:19","ADY":536,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-220","SUBJID":"id-220","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.26273,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-27","TRTSDTM":"2019-03-01 13:33:19","TRTEDTM":"2022-03-01 07:33:19","TRT01SDTM":"2019-03-01 13:33:19","TRT01EDTM":"2021-03-01 01:33:19","TRT02SDTM":"2021-03-01 01:33:19","TRT02EDTM":"2022-03-01 07:33:19","AP01SDTM":"2019-03-01 13:33:19","AP01EDTM":"2021-03-01 01:33:19","AP02SDTM":"2021-03-01 01:33:19","AP02EDTM":"2022-03-01 07:33:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-26","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6068,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.90944,"AVALU":"U/L","BASE2":33.95281,"BASE":3.06118,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.04336,"PCHG2":-3.07298,"CHG":29.84826,"PCHG":975.05595,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-02-14 13:33:19","ADY":716,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-220","SUBJID":"id-220","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.26273,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-27","TRTSDTM":"2019-03-01 13:33:19","TRTEDTM":"2022-03-01 07:33:19","TRT01SDTM":"2019-03-01 13:33:19","TRT01EDTM":"2021-03-01 01:33:19","TRT02SDTM":"2021-03-01 01:33:19","TRT02EDTM":"2022-03-01 07:33:19","AP01SDTM":"2019-03-01 13:33:19","AP01EDTM":"2021-03-01 01:33:19","AP02SDTM":"2021-03-01 01:33:19","AP02EDTM":"2022-03-01 07:33:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-26","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5413,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.44309,"AVALU":"U/L","BASE2":33.95281,"BASE":3.06118,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.49028,"PCHG2":1.444,"CHG":31.3819,"PCHG":1025.15553,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-05-27 13:33:19","ADY":818,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-220","SUBJID":"id-220","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.26273,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-27","TRTSDTM":"2019-03-01 13:33:19","TRTEDTM":"2022-03-01 07:33:19","TRT01SDTM":"2019-03-01 13:33:19","TRT01EDTM":"2021-03-01 01:33:19","TRT02SDTM":"2021-03-01 01:33:19","TRT02EDTM":"2022-03-01 07:33:19","AP01SDTM":"2019-03-01 13:33:19","AP01EDTM":"2021-03-01 01:33:19","AP02SDTM":"2021-03-01 01:33:19","AP02EDTM":"2022-03-01 07:33:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-26","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3820,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.68697,"AVALU":"U/L","BASE2":33.95281,"BASE":3.06118,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.26584,"PCHG2":-47.9072,"CHG":14.62578,"PCHG":477.78191,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-11-15 13:33:19","ADY":990,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-220","SUBJID":"id-220","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.26273,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-27","TRTSDTM":"2019-03-01 13:33:19","TRTEDTM":"2022-03-01 07:33:19","TRT01SDTM":"2019-03-01 13:33:19","TRT01EDTM":"2021-03-01 01:33:19","TRT02SDTM":"2021-03-01 01:33:19","TRT02EDTM":"2022-03-01 07:33:19","AP01SDTM":"2019-03-01 13:33:19","AP01EDTM":"2021-03-01 01:33:19","AP02SDTM":"2021-03-01 01:33:19","AP02EDTM":"2022-03-01 07:33:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-26","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1099,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.46693,"AVALU":"U/L","BASE2":33.95281,"BASE":3.06118,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.48588,"PCHG2":-22.04789,"CHG":23.40575,"PCHG":764.59775,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-01-14 13:33:19","ADY":1050,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-220","SUBJID":"id-220","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.26273,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-27","TRTSDTM":"2019-03-01 13:33:19","TRTEDTM":"2022-03-01 07:33:19","TRT01SDTM":"2019-03-01 13:33:19","TRT01EDTM":"2021-03-01 01:33:19","TRT02SDTM":"2021-03-01 01:33:19","TRT02EDTM":"2022-03-01 07:33:19","AP01SDTM":"2019-03-01 13:33:19","AP01EDTM":"2021-03-01 01:33:19","AP02SDTM":"2021-03-01 01:33:19","AP02EDTM":"2022-03-01 07:33:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-26","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4409,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.68032,"AVALU":"mg/L","BASE2":8.68032,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2019-04-23 13:33:19","ADY":53,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-220","SUBJID":"id-220","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.26273,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-27","TRTSDTM":"2019-03-01 13:33:19","TRTEDTM":"2022-03-01 07:33:19","TRT01SDTM":"2019-03-01 13:33:19","TRT01EDTM":"2021-03-01 01:33:19","TRT02SDTM":"2021-03-01 01:33:19","TRT02EDTM":"2022-03-01 07:33:19","AP01SDTM":"2019-03-01 13:33:19","AP01EDTM":"2021-03-01 01:33:19","AP02SDTM":"2021-03-01 01:33:19","AP02EDTM":"2022-03-01 07:33:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-26","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8317,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.81444,"AVALU":"mg/L","BASE2":8.68032,"BASE":7.81444,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.86588,"PCHG2":-9.97521,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2020-03-05 13:33:19","ADY":370,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-220","SUBJID":"id-220","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.26273,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-27","TRTSDTM":"2019-03-01 13:33:19","TRTEDTM":"2022-03-01 07:33:19","TRT01SDTM":"2019-03-01 13:33:19","TRT01EDTM":"2021-03-01 01:33:19","TRT02SDTM":"2021-03-01 01:33:19","TRT02EDTM":"2022-03-01 07:33:19","AP01SDTM":"2019-03-01 13:33:19","AP01EDTM":"2021-03-01 01:33:19","AP02SDTM":"2021-03-01 01:33:19","AP02EDTM":"2022-03-01 07:33:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-26","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2467,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.4747,"AVALU":"mg/L","BASE2":8.68032,"BASE":7.81444,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20562,"PCHG2":-2.36878,"CHG":0.66026,"PCHG":8.44926,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-08-18 13:33:19","ADY":536,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-220","SUBJID":"id-220","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.26273,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-27","TRTSDTM":"2019-03-01 13:33:19","TRTEDTM":"2022-03-01 07:33:19","TRT01SDTM":"2019-03-01 13:33:19","TRT01EDTM":"2021-03-01 01:33:19","TRT02SDTM":"2021-03-01 01:33:19","TRT02EDTM":"2022-03-01 07:33:19","AP01SDTM":"2019-03-01 13:33:19","AP01EDTM":"2021-03-01 01:33:19","AP02SDTM":"2021-03-01 01:33:19","AP02EDTM":"2022-03-01 07:33:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-26","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5749,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.76154,"AVALU":"mg/L","BASE2":8.68032,"BASE":7.81444,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08122,"PCHG2":0.93569,"CHG":0.9471,"PCHG":12.11988,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-02-14 13:33:19","ADY":716,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-220","SUBJID":"id-220","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.26273,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-27","TRTSDTM":"2019-03-01 13:33:19","TRTEDTM":"2022-03-01 07:33:19","TRT01SDTM":"2019-03-01 13:33:19","TRT01EDTM":"2021-03-01 01:33:19","TRT02SDTM":"2021-03-01 01:33:19","TRT02EDTM":"2022-03-01 07:33:19","AP01SDTM":"2019-03-01 13:33:19","AP01EDTM":"2021-03-01 01:33:19","AP02SDTM":"2021-03-01 01:33:19","AP02EDTM":"2022-03-01 07:33:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-26","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4662,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.82426,"AVALU":"mg/L","BASE2":8.68032,"BASE":7.81444,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.85606,"PCHG2":-9.86206,"CHG":0.00982,"PCHG":0.12568,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-2","ADTM":"2021-05-27 13:33:19","ADY":818,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-220","SUBJID":"id-220","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.26273,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-27","TRTSDTM":"2019-03-01 13:33:19","TRTEDTM":"2022-03-01 07:33:19","TRT01SDTM":"2019-03-01 13:33:19","TRT01EDTM":"2021-03-01 01:33:19","TRT02SDTM":"2021-03-01 01:33:19","TRT02EDTM":"2022-03-01 07:33:19","AP01SDTM":"2019-03-01 13:33:19","AP01EDTM":"2021-03-01 01:33:19","AP02SDTM":"2021-03-01 01:33:19","AP02EDTM":"2022-03-01 07:33:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-26","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7946,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.05043,"AVALU":"mg/L","BASE2":8.68032,"BASE":7.81444,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.37011,"PCHG2":4.26374,"CHG":1.23599,"PCHG":15.8167,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-11-15 13:33:19","ADY":990,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-220","SUBJID":"id-220","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.26273,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-27","TRTSDTM":"2019-03-01 13:33:19","TRTEDTM":"2022-03-01 07:33:19","TRT01SDTM":"2019-03-01 13:33:19","TRT01EDTM":"2021-03-01 01:33:19","TRT02SDTM":"2021-03-01 01:33:19","TRT02EDTM":"2022-03-01 07:33:19","AP01SDTM":"2019-03-01 13:33:19","AP01EDTM":"2021-03-01 01:33:19","AP02SDTM":"2021-03-01 01:33:19","AP02EDTM":"2022-03-01 07:33:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-26","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4191,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.96735,"AVALU":"mg/L","BASE2":8.68032,"BASE":7.81444,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.71297,"PCHG2":-8.21368,"CHG":0.15291,"PCHG":1.95671,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-2","ADTM":"2022-01-14 13:33:19","ADY":1050,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-220","SUBJID":"id-220","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.26273,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-27","TRTSDTM":"2019-03-01 13:33:19","TRTEDTM":"2022-03-01 07:33:19","TRT01SDTM":"2019-03-01 13:33:19","TRT01EDTM":"2021-03-01 01:33:19","TRT02SDTM":"2021-03-01 01:33:19","TRT02EDTM":"2022-03-01 07:33:19","AP01SDTM":"2019-03-01 13:33:19","AP01EDTM":"2021-03-01 01:33:19","AP02SDTM":"2021-03-01 01:33:19","AP02EDTM":"2022-03-01 07:33:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-26","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7007,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92127,"AVALU":"g/L","BASE2":2.92127,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-04-23 13:33:19","ADY":53,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-220","SUBJID":"id-220","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.26273,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-27","TRTSDTM":"2019-03-01 13:33:19","TRTEDTM":"2022-03-01 07:33:19","TRT01SDTM":"2019-03-01 13:33:19","TRT01EDTM":"2021-03-01 01:33:19","TRT02SDTM":"2021-03-01 01:33:19","TRT02EDTM":"2022-03-01 07:33:19","AP01SDTM":"2019-03-01 13:33:19","AP01EDTM":"2021-03-01 01:33:19","AP02SDTM":"2021-03-01 01:33:19","AP02EDTM":"2022-03-01 07:33:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-26","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1433,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9812,"AVALU":"g/L","BASE2":2.92127,"BASE":2.9812,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.05993,"PCHG2":2.05148,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-05 13:33:19","ADY":370,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-220","SUBJID":"id-220","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.26273,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-27","TRTSDTM":"2019-03-01 13:33:19","TRTEDTM":"2022-03-01 07:33:19","TRT01SDTM":"2019-03-01 13:33:19","TRT01EDTM":"2021-03-01 01:33:19","TRT02SDTM":"2021-03-01 01:33:19","TRT02EDTM":"2022-03-01 07:33:19","AP01SDTM":"2019-03-01 13:33:19","AP01EDTM":"2021-03-01 01:33:19","AP02SDTM":"2021-03-01 01:33:19","AP02EDTM":"2022-03-01 07:33:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-26","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8355,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.70652,"AVALU":"g/L","BASE2":2.92127,"BASE":2.9812,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21475,"PCHG2":-7.35133,"CHG":-0.27468,"PCHG":-9.21379,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-18 13:33:19","ADY":536,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-220","SUBJID":"id-220","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.26273,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-27","TRTSDTM":"2019-03-01 13:33:19","TRTEDTM":"2022-03-01 07:33:19","TRT01SDTM":"2019-03-01 13:33:19","TRT01EDTM":"2021-03-01 01:33:19","TRT02SDTM":"2021-03-01 01:33:19","TRT02EDTM":"2022-03-01 07:33:19","AP01SDTM":"2019-03-01 13:33:19","AP01EDTM":"2021-03-01 01:33:19","AP02SDTM":"2021-03-01 01:33:19","AP02EDTM":"2022-03-01 07:33:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-26","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8141,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93627,"AVALU":"g/L","BASE2":2.92127,"BASE":2.9812,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.015,"PCHG2":0.51348,"CHG":-0.04493,"PCHG":-1.50709,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-14 13:33:19","ADY":716,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-220","SUBJID":"id-220","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.26273,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-27","TRTSDTM":"2019-03-01 13:33:19","TRTEDTM":"2022-03-01 07:33:19","TRT01SDTM":"2019-03-01 13:33:19","TRT01EDTM":"2021-03-01 01:33:19","TRT02SDTM":"2021-03-01 01:33:19","TRT02EDTM":"2022-03-01 07:33:19","AP01SDTM":"2019-03-01 13:33:19","AP01EDTM":"2021-03-01 01:33:19","AP02SDTM":"2021-03-01 01:33:19","AP02EDTM":"2022-03-01 07:33:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-26","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6752,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96861,"AVALU":"g/L","BASE2":2.92127,"BASE":2.9812,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04734,"PCHG2":1.62053,"CHG":-0.01259,"PCHG":-0.42229,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-27 13:33:19","ADY":818,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-220","SUBJID":"id-220","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.26273,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-27","TRTSDTM":"2019-03-01 13:33:19","TRTEDTM":"2022-03-01 07:33:19","TRT01SDTM":"2019-03-01 13:33:19","TRT01EDTM":"2021-03-01 01:33:19","TRT02SDTM":"2021-03-01 01:33:19","TRT02EDTM":"2022-03-01 07:33:19","AP01SDTM":"2019-03-01 13:33:19","AP01EDTM":"2021-03-01 01:33:19","AP02SDTM":"2021-03-01 01:33:19","AP02EDTM":"2022-03-01 07:33:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-26","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4361,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93662,"AVALU":"g/L","BASE2":2.92127,"BASE":2.9812,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01534,"PCHG2":0.52526,"CHG":-0.04459,"PCHG":-1.49555,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-15 13:33:19","ADY":990,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-220","SUBJID":"id-220","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":10.26273,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-27","TRTSDTM":"2019-03-01 13:33:19","TRTEDTM":"2022-03-01 07:33:19","TRT01SDTM":"2019-03-01 13:33:19","TRT01EDTM":"2021-03-01 01:33:19","TRT02SDTM":"2021-03-01 01:33:19","TRT02EDTM":"2022-03-01 07:33:19","AP01SDTM":"2019-03-01 13:33:19","AP01EDTM":"2021-03-01 01:33:19","AP02SDTM":"2021-03-01 01:33:19","AP02EDTM":"2022-03-01 07:33:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-26","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2777,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7946,"AVALU":"g/L","BASE2":2.92127,"BASE":2.9812,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12667,"PCHG2":-4.3361,"CHG":-0.1866,"PCHG":-6.25918,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-14 13:33:19","ADY":1050,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-222","SUBJID":"id-222","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.65329,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-22","TRTSDTM":"2020-02-25 06:30:30","TRTEDTM":"2023-02-25 00:30:30","TRT01SDTM":"2020-02-25 06:30:30","TRT01EDTM":"2022-02-24 18:30:30","TRT02SDTM":"2022-02-24 18:30:30","TRT02EDTM":"2023-02-25 00:30:30","AP01SDTM":"2020-02-25 06:30:30","AP01EDTM":"2022-02-24 18:30:30","AP02SDTM":"2022-02-24 18:30:30","AP02EDTM":"2023-02-25 00:30:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-10","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6402,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":42.97662,"AVALU":"U/L","BASE2":42.97662,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-10 06:30:30","ADY":14,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-222","SUBJID":"id-222","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.65329,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-22","TRTSDTM":"2020-02-25 06:30:30","TRTEDTM":"2023-02-25 00:30:30","TRT01SDTM":"2020-02-25 06:30:30","TRT01EDTM":"2022-02-24 18:30:30","TRT02SDTM":"2022-02-24 18:30:30","TRT02EDTM":"2023-02-25 00:30:30","AP01SDTM":"2020-02-25 06:30:30","AP01EDTM":"2022-02-24 18:30:30","AP02SDTM":"2022-02-24 18:30:30","AP02EDTM":"2023-02-25 00:30:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-10","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1724,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.85144,"AVALU":"U/L","BASE2":42.97662,"BASE":8.85144,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-34.12517,"PCHG2":-79.40405,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-17 06:30:30","ADY":143,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-222","SUBJID":"id-222","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.65329,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-22","TRTSDTM":"2020-02-25 06:30:30","TRTEDTM":"2023-02-25 00:30:30","TRT01SDTM":"2020-02-25 06:30:30","TRT01EDTM":"2022-02-24 18:30:30","TRT02SDTM":"2022-02-24 18:30:30","TRT02EDTM":"2023-02-25 00:30:30","AP01SDTM":"2020-02-25 06:30:30","AP01EDTM":"2022-02-24 18:30:30","AP02SDTM":"2022-02-24 18:30:30","AP02EDTM":"2023-02-25 00:30:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-10","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2566,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.04878,"AVALU":"U/L","BASE2":42.97662,"BASE":8.85144,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-36.92784,"PCHG2":-85.92541,"CHG":-2.80266,"PCHG":-31.66333,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-11-20 06:30:30","ADY":269,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-222","SUBJID":"id-222","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.65329,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-22","TRTSDTM":"2020-02-25 06:30:30","TRTEDTM":"2023-02-25 00:30:30","TRT01SDTM":"2020-02-25 06:30:30","TRT01EDTM":"2022-02-24 18:30:30","TRT02SDTM":"2022-02-24 18:30:30","TRT02EDTM":"2023-02-25 00:30:30","AP01SDTM":"2020-02-25 06:30:30","AP01EDTM":"2022-02-24 18:30:30","AP02SDTM":"2022-02-24 18:30:30","AP02EDTM":"2023-02-25 00:30:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-10","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2041,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.23704,"AVALU":"U/L","BASE2":42.97662,"BASE":8.85144,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.73958,"PCHG2":-27.3162,"CHG":22.3856,"PCHG":252.90341,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-19 06:30:30","ADY":360,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-222","SUBJID":"id-222","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.65329,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-22","TRTSDTM":"2020-02-25 06:30:30","TRTEDTM":"2023-02-25 00:30:30","TRT01SDTM":"2020-02-25 06:30:30","TRT01EDTM":"2022-02-24 18:30:30","TRT02SDTM":"2022-02-24 18:30:30","TRT02EDTM":"2023-02-25 00:30:30","AP01SDTM":"2020-02-25 06:30:30","AP01EDTM":"2022-02-24 18:30:30","AP02SDTM":"2022-02-24 18:30:30","AP02EDTM":"2023-02-25 00:30:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-10","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7603,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.62264,"AVALU":"U/L","BASE2":42.97662,"BASE":8.85144,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-37.35398,"PCHG2":-86.91698,"CHG":-3.2288,"PCHG":-36.47769,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-08-25 06:30:30","ADY":912,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-222","SUBJID":"id-222","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.65329,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-22","TRTSDTM":"2020-02-25 06:30:30","TRTEDTM":"2023-02-25 00:30:30","TRT01SDTM":"2020-02-25 06:30:30","TRT01EDTM":"2022-02-24 18:30:30","TRT02SDTM":"2022-02-24 18:30:30","TRT02EDTM":"2023-02-25 00:30:30","AP01SDTM":"2020-02-25 06:30:30","AP01EDTM":"2022-02-24 18:30:30","AP02SDTM":"2022-02-24 18:30:30","AP02EDTM":"2023-02-25 00:30:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-10","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6824,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.1178,"AVALU":"U/L","BASE2":42.97662,"BASE":8.85144,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.85881,"PCHG2":-22.93995,"CHG":24.26636,"PCHG":274.15151,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-30 06:30:30","ADY":1009,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-222","SUBJID":"id-222","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.65329,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-22","TRTSDTM":"2020-02-25 06:30:30","TRTEDTM":"2023-02-25 00:30:30","TRT01SDTM":"2020-02-25 06:30:30","TRT01EDTM":"2022-02-24 18:30:30","TRT02SDTM":"2022-02-24 18:30:30","TRT02EDTM":"2023-02-25 00:30:30","AP01SDTM":"2020-02-25 06:30:30","AP01EDTM":"2022-02-24 18:30:30","AP02SDTM":"2022-02-24 18:30:30","AP02EDTM":"2023-02-25 00:30:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-10","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6121,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.35281,"AVALU":"U/L","BASE2":42.97662,"BASE":8.85144,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.6238,"PCHG2":-24.71997,"CHG":23.50137,"PCHG":265.50895,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-14 06:30:30","ADY":1085,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-222","SUBJID":"id-222","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.65329,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-22","TRTSDTM":"2020-02-25 06:30:30","TRTEDTM":"2023-02-25 00:30:30","TRT01SDTM":"2020-02-25 06:30:30","TRT01EDTM":"2022-02-24 18:30:30","TRT02SDTM":"2022-02-24 18:30:30","TRT02EDTM":"2023-02-25 00:30:30","AP01SDTM":"2020-02-25 06:30:30","AP01EDTM":"2022-02-24 18:30:30","AP02SDTM":"2022-02-24 18:30:30","AP02EDTM":"2023-02-25 00:30:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-10","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8130,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.26555,"AVALU":"mg/L","BASE2":10.26555,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-03-10 06:30:30","ADY":14,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-222","SUBJID":"id-222","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.65329,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-22","TRTSDTM":"2020-02-25 06:30:30","TRTEDTM":"2023-02-25 00:30:30","TRT01SDTM":"2020-02-25 06:30:30","TRT01EDTM":"2022-02-24 18:30:30","TRT02SDTM":"2022-02-24 18:30:30","TRT02EDTM":"2023-02-25 00:30:30","AP01SDTM":"2020-02-25 06:30:30","AP01EDTM":"2022-02-24 18:30:30","AP02SDTM":"2022-02-24 18:30:30","AP02EDTM":"2023-02-25 00:30:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-10","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":175,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.1859,"AVALU":"mg/L","BASE2":10.26555,"BASE":10.1859,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.07965,"PCHG2":-0.77591,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-07-17 06:30:30","ADY":143,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-222","SUBJID":"id-222","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.65329,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-22","TRTSDTM":"2020-02-25 06:30:30","TRTEDTM":"2023-02-25 00:30:30","TRT01SDTM":"2020-02-25 06:30:30","TRT01EDTM":"2022-02-24 18:30:30","TRT02SDTM":"2022-02-24 18:30:30","TRT02EDTM":"2023-02-25 00:30:30","AP01SDTM":"2020-02-25 06:30:30","AP01EDTM":"2022-02-24 18:30:30","AP02SDTM":"2022-02-24 18:30:30","AP02EDTM":"2023-02-25 00:30:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-10","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7208,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.19474,"AVALU":"mg/L","BASE2":10.26555,"BASE":10.1859,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.07081,"PCHG2":-10.43109,"CHG":-0.99116,"PCHG":-9.73068,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-11-20 06:30:30","ADY":269,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-222","SUBJID":"id-222","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.65329,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-22","TRTSDTM":"2020-02-25 06:30:30","TRTEDTM":"2023-02-25 00:30:30","TRT01SDTM":"2020-02-25 06:30:30","TRT01EDTM":"2022-02-24 18:30:30","TRT02SDTM":"2022-02-24 18:30:30","TRT02EDTM":"2023-02-25 00:30:30","AP01SDTM":"2020-02-25 06:30:30","AP01EDTM":"2022-02-24 18:30:30","AP02SDTM":"2022-02-24 18:30:30","AP02EDTM":"2023-02-25 00:30:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-10","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7161,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.91621,"AVALU":"mg/L","BASE2":10.26555,"BASE":10.1859,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.34934,"PCHG2":-3.40302,"CHG":-0.26969,"PCHG":-2.64765,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-02-19 06:30:30","ADY":360,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-222","SUBJID":"id-222","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.65329,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-22","TRTSDTM":"2020-02-25 06:30:30","TRTEDTM":"2023-02-25 00:30:30","TRT01SDTM":"2020-02-25 06:30:30","TRT01EDTM":"2022-02-24 18:30:30","TRT02SDTM":"2022-02-24 18:30:30","TRT02EDTM":"2023-02-25 00:30:30","AP01SDTM":"2020-02-25 06:30:30","AP01EDTM":"2022-02-24 18:30:30","AP02SDTM":"2022-02-24 18:30:30","AP02EDTM":"2023-02-25 00:30:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-10","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1939,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.69119,"AVALU":"mg/L","BASE2":10.26555,"BASE":10.1859,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.57436,"PCHG2":-15.33638,"CHG":-1.49471,"PCHG":-14.67433,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2022-08-25 06:30:30","ADY":912,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-222","SUBJID":"id-222","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.65329,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-22","TRTSDTM":"2020-02-25 06:30:30","TRTEDTM":"2023-02-25 00:30:30","TRT01SDTM":"2020-02-25 06:30:30","TRT01EDTM":"2022-02-24 18:30:30","TRT02SDTM":"2022-02-24 18:30:30","TRT02EDTM":"2023-02-25 00:30:30","AP01SDTM":"2020-02-25 06:30:30","AP01EDTM":"2022-02-24 18:30:30","AP02SDTM":"2022-02-24 18:30:30","AP02EDTM":"2023-02-25 00:30:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-10","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8178,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.66104,"AVALU":"mg/L","BASE2":10.26555,"BASE":10.1859,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.60452,"PCHG2":-15.63011,"CHG":-1.52487,"PCHG":-14.97035,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2022-11-30 06:30:30","ADY":1009,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-222","SUBJID":"id-222","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.65329,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-22","TRTSDTM":"2020-02-25 06:30:30","TRTEDTM":"2023-02-25 00:30:30","TRT01SDTM":"2020-02-25 06:30:30","TRT01EDTM":"2022-02-24 18:30:30","TRT02SDTM":"2022-02-24 18:30:30","TRT02EDTM":"2023-02-25 00:30:30","AP01SDTM":"2020-02-25 06:30:30","AP01EDTM":"2022-02-24 18:30:30","AP02SDTM":"2022-02-24 18:30:30","AP02EDTM":"2023-02-25 00:30:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-10","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5958,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.5736,"AVALU":"mg/L","BASE2":10.26555,"BASE":10.1859,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.69195,"PCHG2":-16.48183,"CHG":-1.6123,"PCHG":-15.82874,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2023-02-14 06:30:30","ADY":1085,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-222","SUBJID":"id-222","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.65329,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-22","TRTSDTM":"2020-02-25 06:30:30","TRTEDTM":"2023-02-25 00:30:30","TRT01SDTM":"2020-02-25 06:30:30","TRT01EDTM":"2022-02-24 18:30:30","TRT02SDTM":"2022-02-24 18:30:30","TRT02EDTM":"2023-02-25 00:30:30","AP01SDTM":"2020-02-25 06:30:30","AP01EDTM":"2022-02-24 18:30:30","AP02SDTM":"2022-02-24 18:30:30","AP02EDTM":"2023-02-25 00:30:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-10","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":493,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91886,"AVALU":"g/L","BASE2":2.91886,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"2","ADTM":"2020-03-10 06:30:30","ADY":14,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-222","SUBJID":"id-222","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.65329,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-22","TRTSDTM":"2020-02-25 06:30:30","TRTEDTM":"2023-02-25 00:30:30","TRT01SDTM":"2020-02-25 06:30:30","TRT01EDTM":"2022-02-24 18:30:30","TRT02SDTM":"2022-02-24 18:30:30","TRT02EDTM":"2023-02-25 00:30:30","AP01SDTM":"2020-02-25 06:30:30","AP01EDTM":"2022-02-24 18:30:30","AP02SDTM":"2022-02-24 18:30:30","AP02EDTM":"2023-02-25 00:30:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-10","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8327,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.08584,"AVALU":"g/L","BASE2":2.91886,"BASE":3.08584,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.16698,"PCHG2":5.72067,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2020-07-17 06:30:30","ADY":143,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-222","SUBJID":"id-222","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.65329,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-22","TRTSDTM":"2020-02-25 06:30:30","TRTEDTM":"2023-02-25 00:30:30","TRT01SDTM":"2020-02-25 06:30:30","TRT01EDTM":"2022-02-24 18:30:30","TRT02SDTM":"2022-02-24 18:30:30","TRT02EDTM":"2023-02-25 00:30:30","AP01SDTM":"2020-02-25 06:30:30","AP01EDTM":"2022-02-24 18:30:30","AP02SDTM":"2022-02-24 18:30:30","AP02EDTM":"2023-02-25 00:30:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-10","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":134,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91877,"AVALU":"g/L","BASE2":2.91886,"BASE":3.08584,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00009,"PCHG2":-0.0032,"CHG":-0.16707,"PCHG":-5.41415,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2020-11-20 06:30:30","ADY":269,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-222","SUBJID":"id-222","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.65329,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-22","TRTSDTM":"2020-02-25 06:30:30","TRTEDTM":"2023-02-25 00:30:30","TRT01SDTM":"2020-02-25 06:30:30","TRT01EDTM":"2022-02-24 18:30:30","TRT02SDTM":"2022-02-24 18:30:30","TRT02EDTM":"2023-02-25 00:30:30","AP01SDTM":"2020-02-25 06:30:30","AP01EDTM":"2022-02-24 18:30:30","AP02SDTM":"2022-02-24 18:30:30","AP02EDTM":"2023-02-25 00:30:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-10","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4449,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91887,"AVALU":"g/L","BASE2":2.91886,"BASE":3.08584,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00001,"PCHG2":0.00045,"CHG":-0.16697,"PCHG":-5.4107,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-02-19 06:30:30","ADY":360,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-222","SUBJID":"id-222","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.65329,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-22","TRTSDTM":"2020-02-25 06:30:30","TRTEDTM":"2023-02-25 00:30:30","TRT01SDTM":"2020-02-25 06:30:30","TRT01EDTM":"2022-02-24 18:30:30","TRT02SDTM":"2022-02-24 18:30:30","TRT02EDTM":"2023-02-25 00:30:30","AP01SDTM":"2020-02-25 06:30:30","AP01EDTM":"2022-02-24 18:30:30","AP02SDTM":"2022-02-24 18:30:30","AP02EDTM":"2023-02-25 00:30:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-10","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6692,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95602,"AVALU":"g/L","BASE2":2.91886,"BASE":3.08584,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03716,"PCHG2":1.27306,"CHG":-0.12982,"PCHG":-4.20695,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-08-25 06:30:30","ADY":912,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-222","SUBJID":"id-222","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.65329,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-22","TRTSDTM":"2020-02-25 06:30:30","TRTEDTM":"2023-02-25 00:30:30","TRT01SDTM":"2020-02-25 06:30:30","TRT01EDTM":"2022-02-24 18:30:30","TRT02SDTM":"2022-02-24 18:30:30","TRT02EDTM":"2023-02-25 00:30:30","AP01SDTM":"2020-02-25 06:30:30","AP01EDTM":"2022-02-24 18:30:30","AP02SDTM":"2022-02-24 18:30:30","AP02EDTM":"2023-02-25 00:30:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-10","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7762,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74503,"AVALU":"g/L","BASE2":2.91886,"BASE":3.08584,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17383,"PCHG2":-5.95554,"CHG":-0.34081,"PCHG":-11.0444,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-11-30 06:30:30","ADY":1009,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-222","SUBJID":"id-222","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.65329,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-22","TRTSDTM":"2020-02-25 06:30:30","TRTEDTM":"2023-02-25 00:30:30","TRT01SDTM":"2020-02-25 06:30:30","TRT01EDTM":"2022-02-24 18:30:30","TRT02SDTM":"2022-02-24 18:30:30","TRT02EDTM":"2023-02-25 00:30:30","AP01SDTM":"2020-02-25 06:30:30","AP01EDTM":"2022-02-24 18:30:30","AP02SDTM":"2022-02-24 18:30:30","AP02EDTM":"2023-02-25 00:30:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-25","EOSDY":1096,"LSTALVDT":"2023-03-10","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3956,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94766,"AVALU":"g/L","BASE2":2.91886,"BASE":3.08584,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0288,"PCHG2":0.98671,"CHG":-0.13818,"PCHG":-4.4778,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2023-02-14 06:30:30","ADY":1085,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-24","SUBJID":"id-24","SITEID":"CHN-11","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.98174,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-29 16:45:10","TRTEDTM":"2023-10-30 10:45:10","TRT01SDTM":"2020-10-29 16:45:10","TRT01EDTM":"2022-10-30 04:45:10","TRT02SDTM":"2022-10-30 04:45:10","TRT02EDTM":"2023-10-30 10:45:10","AP01SDTM":"2020-10-29 16:45:10","AP01EDTM":"2022-10-30 04:45:10","AP02SDTM":"2022-10-30 04:45:10","AP02EDTM":"2023-10-30 10:45:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-30","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4284,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.04399,"AVALU":"U/L","BASE2":18.04399,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-06 16:45:10","ADY":159,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-24","SUBJID":"id-24","SITEID":"CHN-11","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.98174,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-29 16:45:10","TRTEDTM":"2023-10-30 10:45:10","TRT01SDTM":"2020-10-29 16:45:10","TRT01EDTM":"2022-10-30 04:45:10","TRT02SDTM":"2022-10-30 04:45:10","TRT02EDTM":"2023-10-30 10:45:10","AP01SDTM":"2020-10-29 16:45:10","AP01EDTM":"2022-10-30 04:45:10","AP02SDTM":"2022-10-30 04:45:10","AP02EDTM":"2023-10-30 10:45:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-30","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1416,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.67765,"AVALU":"U/L","BASE2":18.04399,"BASE":34.67765,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":16.63367,"PCHG2":92.18398,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-05 16:45:10","ADY":249,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-24","SUBJID":"id-24","SITEID":"CHN-11","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.98174,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-29 16:45:10","TRTEDTM":"2023-10-30 10:45:10","TRT01SDTM":"2020-10-29 16:45:10","TRT01EDTM":"2022-10-30 04:45:10","TRT02SDTM":"2022-10-30 04:45:10","TRT02EDTM":"2023-10-30 10:45:10","AP01SDTM":"2020-10-29 16:45:10","AP01EDTM":"2022-10-30 04:45:10","AP02SDTM":"2022-10-30 04:45:10","AP02EDTM":"2023-10-30 10:45:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-30","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1391,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.41332,"AVALU":"U/L","BASE2":18.04399,"BASE":34.67765,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.63067,"PCHG2":-64.4573,"CHG":-28.26433,"PCHG":-81.5059,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-08-01 16:45:10","ADY":276,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-24","SUBJID":"id-24","SITEID":"CHN-11","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.98174,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-29 16:45:10","TRTEDTM":"2023-10-30 10:45:10","TRT01SDTM":"2020-10-29 16:45:10","TRT01EDTM":"2022-10-30 04:45:10","TRT02SDTM":"2022-10-30 04:45:10","TRT02EDTM":"2023-10-30 10:45:10","AP01SDTM":"2020-10-29 16:45:10","AP01EDTM":"2022-10-30 04:45:10","AP02SDTM":"2022-10-30 04:45:10","AP02EDTM":"2023-10-30 10:45:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-30","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2405,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.25436,"AVALU":"U/L","BASE2":18.04399,"BASE":34.67765,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.21037,"PCHG2":51.04401,"CHG":-7.42329,"PCHG":-21.40656,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-22 16:45:10","ADY":419,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-24","SUBJID":"id-24","SITEID":"CHN-11","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.98174,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-29 16:45:10","TRTEDTM":"2023-10-30 10:45:10","TRT01SDTM":"2020-10-29 16:45:10","TRT01EDTM":"2022-10-30 04:45:10","TRT02SDTM":"2022-10-30 04:45:10","TRT02EDTM":"2023-10-30 10:45:10","AP01SDTM":"2020-10-29 16:45:10","AP01EDTM":"2022-10-30 04:45:10","AP02SDTM":"2022-10-30 04:45:10","AP02EDTM":"2023-10-30 10:45:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-30","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3910,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.58166,"AVALU":"U/L","BASE2":18.04399,"BASE":34.67765,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.46233,"PCHG2":-96.77645,"CHG":-34.096,"PCHG":-98.32267,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-04-04 16:45:10","ADY":522,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-24","SUBJID":"id-24","SITEID":"CHN-11","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.98174,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-29 16:45:10","TRTEDTM":"2023-10-30 10:45:10","TRT01SDTM":"2020-10-29 16:45:10","TRT01EDTM":"2022-10-30 04:45:10","TRT02SDTM":"2022-10-30 04:45:10","TRT02EDTM":"2023-10-30 10:45:10","AP01SDTM":"2020-10-29 16:45:10","AP01EDTM":"2022-10-30 04:45:10","AP02SDTM":"2022-10-30 04:45:10","AP02EDTM":"2023-10-30 10:45:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-30","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2558,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.57911,"AVALU":"U/L","BASE2":18.04399,"BASE":34.67765,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.53512,"PCHG2":47.30177,"CHG":-8.09854,"PCHG":-23.35378,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-06 16:45:10","ADY":738,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-24","SUBJID":"id-24","SITEID":"CHN-11","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.98174,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-29 16:45:10","TRTEDTM":"2023-10-30 10:45:10","TRT01SDTM":"2020-10-29 16:45:10","TRT01EDTM":"2022-10-30 04:45:10","TRT02SDTM":"2022-10-30 04:45:10","TRT02EDTM":"2023-10-30 10:45:10","AP01SDTM":"2020-10-29 16:45:10","AP01EDTM":"2022-10-30 04:45:10","AP02SDTM":"2022-10-30 04:45:10","AP02EDTM":"2023-10-30 10:45:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-30","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3756,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.71754,"AVALU":"U/L","BASE2":18.04399,"BASE":34.67765,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.32645,"PCHG2":-1.80918,"CHG":-16.96011,"PCHG":-48.90791,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-12 16:45:10","ADY":956,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-24","SUBJID":"id-24","SITEID":"CHN-11","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.98174,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-29 16:45:10","TRTEDTM":"2023-10-30 10:45:10","TRT01SDTM":"2020-10-29 16:45:10","TRT01EDTM":"2022-10-30 04:45:10","TRT02SDTM":"2022-10-30 04:45:10","TRT02EDTM":"2023-10-30 10:45:10","AP01SDTM":"2020-10-29 16:45:10","AP01EDTM":"2022-10-30 04:45:10","AP02SDTM":"2022-10-30 04:45:10","AP02EDTM":"2023-10-30 10:45:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-30","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3857,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.31613,"AVALU":"mg/L","BASE2":9.31613,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-06 16:45:10","ADY":159,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-24","SUBJID":"id-24","SITEID":"CHN-11","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.98174,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-29 16:45:10","TRTEDTM":"2023-10-30 10:45:10","TRT01SDTM":"2020-10-29 16:45:10","TRT01EDTM":"2022-10-30 04:45:10","TRT02SDTM":"2022-10-30 04:45:10","TRT02EDTM":"2023-10-30 10:45:10","AP01SDTM":"2020-10-29 16:45:10","AP01EDTM":"2022-10-30 04:45:10","AP02SDTM":"2022-10-30 04:45:10","AP02EDTM":"2023-10-30 10:45:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-30","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5177,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.49775,"AVALU":"mg/L","BASE2":9.31613,"BASE":9.49775,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.18162,"PCHG2":1.94949,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-05 16:45:10","ADY":249,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-24","SUBJID":"id-24","SITEID":"CHN-11","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.98174,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-29 16:45:10","TRTEDTM":"2023-10-30 10:45:10","TRT01SDTM":"2020-10-29 16:45:10","TRT01EDTM":"2022-10-30 04:45:10","TRT02SDTM":"2022-10-30 04:45:10","TRT02EDTM":"2023-10-30 10:45:10","AP01SDTM":"2020-10-29 16:45:10","AP01EDTM":"2022-10-30 04:45:10","AP02SDTM":"2022-10-30 04:45:10","AP02EDTM":"2023-10-30 10:45:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-30","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6282,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.50173,"AVALU":"mg/L","BASE2":9.31613,"BASE":9.49775,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.8144,"PCHG2":-8.74185,"CHG":-0.99602,"PCHG":-10.4869,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-01 16:45:10","ADY":276,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-24","SUBJID":"id-24","SITEID":"CHN-11","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.98174,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-29 16:45:10","TRTEDTM":"2023-10-30 10:45:10","TRT01SDTM":"2020-10-29 16:45:10","TRT01EDTM":"2022-10-30 04:45:10","TRT02SDTM":"2022-10-30 04:45:10","TRT02EDTM":"2023-10-30 10:45:10","AP01SDTM":"2020-10-29 16:45:10","AP01EDTM":"2022-10-30 04:45:10","AP02SDTM":"2022-10-30 04:45:10","AP02EDTM":"2023-10-30 10:45:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-30","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5418,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.12195,"AVALU":"mg/L","BASE2":9.31613,"BASE":9.49775,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.19419,"PCHG2":-12.81848,"CHG":-1.3758,"PCHG":-14.48558,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-22 16:45:10","ADY":419,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-24","SUBJID":"id-24","SITEID":"CHN-11","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.98174,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-29 16:45:10","TRTEDTM":"2023-10-30 10:45:10","TRT01SDTM":"2020-10-29 16:45:10","TRT01EDTM":"2022-10-30 04:45:10","TRT02SDTM":"2022-10-30 04:45:10","TRT02EDTM":"2023-10-30 10:45:10","AP01SDTM":"2020-10-29 16:45:10","AP01EDTM":"2022-10-30 04:45:10","AP02SDTM":"2022-10-30 04:45:10","AP02EDTM":"2023-10-30 10:45:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-30","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":105,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.82064,"AVALU":"mg/L","BASE2":9.31613,"BASE":9.49775,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.50451,"PCHG2":5.41544,"CHG":0.32289,"PCHG":3.39967,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-04 16:45:10","ADY":522,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-24","SUBJID":"id-24","SITEID":"CHN-11","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.98174,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-29 16:45:10","TRTEDTM":"2023-10-30 10:45:10","TRT01SDTM":"2020-10-29 16:45:10","TRT01EDTM":"2022-10-30 04:45:10","TRT02SDTM":"2022-10-30 04:45:10","TRT02EDTM":"2023-10-30 10:45:10","AP01SDTM":"2020-10-29 16:45:10","AP01EDTM":"2022-10-30 04:45:10","AP02SDTM":"2022-10-30 04:45:10","AP02EDTM":"2023-10-30 10:45:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-30","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3989,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.8875,"AVALU":"mg/L","BASE2":9.31613,"BASE":9.49775,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.42864,"PCHG2":-26.06915,"CHG":-2.61025,"PCHG":-27.48287,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2022-11-06 16:45:10","ADY":738,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-24","SUBJID":"id-24","SITEID":"CHN-11","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.98174,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-29 16:45:10","TRTEDTM":"2023-10-30 10:45:10","TRT01SDTM":"2020-10-29 16:45:10","TRT01EDTM":"2022-10-30 04:45:10","TRT02SDTM":"2022-10-30 04:45:10","TRT02EDTM":"2023-10-30 10:45:10","AP01SDTM":"2020-10-29 16:45:10","AP01EDTM":"2022-10-30 04:45:10","AP02SDTM":"2022-10-30 04:45:10","AP02EDTM":"2023-10-30 10:45:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-30","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6273,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.66413,"AVALU":"mg/L","BASE2":9.31613,"BASE":9.49775,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.652,"PCHG2":-6.99864,"CHG":-0.83362,"PCHG":-8.77702,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-12 16:45:10","ADY":956,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-24","SUBJID":"id-24","SITEID":"CHN-11","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.98174,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-29 16:45:10","TRTEDTM":"2023-10-30 10:45:10","TRT01SDTM":"2020-10-29 16:45:10","TRT01EDTM":"2022-10-30 04:45:10","TRT02SDTM":"2022-10-30 04:45:10","TRT02EDTM":"2023-10-30 10:45:10","AP01SDTM":"2020-10-29 16:45:10","AP01EDTM":"2022-10-30 04:45:10","AP02SDTM":"2022-10-30 04:45:10","AP02EDTM":"2023-10-30 10:45:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-30","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":415,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93127,"AVALU":"g/L","BASE2":2.93127,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-06 16:45:10","ADY":159,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-24","SUBJID":"id-24","SITEID":"CHN-11","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.98174,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-29 16:45:10","TRTEDTM":"2023-10-30 10:45:10","TRT01SDTM":"2020-10-29 16:45:10","TRT01EDTM":"2022-10-30 04:45:10","TRT02SDTM":"2022-10-30 04:45:10","TRT02EDTM":"2023-10-30 10:45:10","AP01SDTM":"2020-10-29 16:45:10","AP01EDTM":"2022-10-30 04:45:10","AP02SDTM":"2022-10-30 04:45:10","AP02EDTM":"2023-10-30 10:45:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-30","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":313,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93079,"AVALU":"g/L","BASE2":2.93127,"BASE":2.93079,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.00048,"PCHG2":-0.01624,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-05 16:45:10","ADY":249,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-24","SUBJID":"id-24","SITEID":"CHN-11","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.98174,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-29 16:45:10","TRTEDTM":"2023-10-30 10:45:10","TRT01SDTM":"2020-10-29 16:45:10","TRT01EDTM":"2022-10-30 04:45:10","TRT02SDTM":"2022-10-30 04:45:10","TRT02EDTM":"2023-10-30 10:45:10","AP01SDTM":"2020-10-29 16:45:10","AP01EDTM":"2022-10-30 04:45:10","AP02SDTM":"2022-10-30 04:45:10","AP02EDTM":"2023-10-30 10:45:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-30","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3125,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98013,"AVALU":"g/L","BASE2":2.93127,"BASE":2.93079,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04887,"PCHG2":1.66704,"CHG":0.04934,"PCHG":1.68355,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-01 16:45:10","ADY":276,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-24","SUBJID":"id-24","SITEID":"CHN-11","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.98174,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-29 16:45:10","TRTEDTM":"2023-10-30 10:45:10","TRT01SDTM":"2020-10-29 16:45:10","TRT01EDTM":"2022-10-30 04:45:10","TRT02SDTM":"2022-10-30 04:45:10","TRT02EDTM":"2023-10-30 10:45:10","AP01SDTM":"2020-10-29 16:45:10","AP01EDTM":"2022-10-30 04:45:10","AP02SDTM":"2022-10-30 04:45:10","AP02EDTM":"2023-10-30 10:45:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-30","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6086,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86024,"AVALU":"g/L","BASE2":2.93127,"BASE":2.93079,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07102,"PCHG2":-2.423,"CHG":-0.07055,"PCHG":-2.40715,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-22 16:45:10","ADY":419,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-24","SUBJID":"id-24","SITEID":"CHN-11","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.98174,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-29 16:45:10","TRTEDTM":"2023-10-30 10:45:10","TRT01SDTM":"2020-10-29 16:45:10","TRT01EDTM":"2022-10-30 04:45:10","TRT02SDTM":"2022-10-30 04:45:10","TRT02EDTM":"2023-10-30 10:45:10","AP01SDTM":"2020-10-29 16:45:10","AP01EDTM":"2022-10-30 04:45:10","AP02SDTM":"2022-10-30 04:45:10","AP02EDTM":"2023-10-30 10:45:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-30","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7136,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8846,"AVALU":"g/L","BASE2":2.93127,"BASE":2.93079,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04667,"PCHG2":-1.59206,"CHG":-0.04619,"PCHG":-1.57608,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-04 16:45:10","ADY":522,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-24","SUBJID":"id-24","SITEID":"CHN-11","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.98174,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-29 16:45:10","TRTEDTM":"2023-10-30 10:45:10","TRT01SDTM":"2020-10-29 16:45:10","TRT01EDTM":"2022-10-30 04:45:10","TRT02SDTM":"2022-10-30 04:45:10","TRT02EDTM":"2023-10-30 10:45:10","AP01SDTM":"2020-10-29 16:45:10","AP01EDTM":"2022-10-30 04:45:10","AP02SDTM":"2022-10-30 04:45:10","AP02EDTM":"2023-10-30 10:45:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-30","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6142,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89936,"AVALU":"g/L","BASE2":2.93127,"BASE":2.93079,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03191,"PCHG2":-1.08866,"CHG":-0.03144,"PCHG":-1.07259,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-06 16:45:10","ADY":738,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-24","SUBJID":"id-24","SITEID":"CHN-11","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.98174,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-25","TRTSDTM":"2020-10-29 16:45:10","TRTEDTM":"2023-10-30 10:45:10","TRT01SDTM":"2020-10-29 16:45:10","TRT01EDTM":"2022-10-30 04:45:10","TRT02SDTM":"2022-10-30 04:45:10","TRT02EDTM":"2023-10-30 10:45:10","AP01SDTM":"2020-10-29 16:45:10","AP01EDTM":"2022-10-30 04:45:10","AP02SDTM":"2022-10-30 04:45:10","AP02EDTM":"2023-10-30 10:45:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-30","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4833,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96293,"AVALU":"g/L","BASE2":2.93127,"BASE":2.93079,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03166,"PCHG2":1.08008,"CHG":0.03214,"PCHG":1.09649,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-12 16:45:10","ADY":956,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-244","SUBJID":"id-244","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.26417,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-14","TRTSDTM":"2020-07-17 02:53:24","TRTEDTM":"2023-07-17 20:53:24","TRT01SDTM":"2020-07-17 02:53:24","TRT01EDTM":"2022-07-17 14:53:24","TRT02SDTM":"2022-07-17 14:53:24","TRT02EDTM":"2023-07-17 20:53:24","AP01SDTM":"2020-07-17 02:53:24","AP01EDTM":"2022-07-17 14:53:24","AP02SDTM":"2022-07-17 14:53:24","AP02EDTM":"2023-07-17 20:53:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-07-29","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1048,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.9813,"AVALU":"U/L","BASE2":21.9813,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-08 02:53:24","ADY":479,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-244","SUBJID":"id-244","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.26417,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-14","TRTSDTM":"2020-07-17 02:53:24","TRTEDTM":"2023-07-17 20:53:24","TRT01SDTM":"2020-07-17 02:53:24","TRT01EDTM":"2022-07-17 14:53:24","TRT02SDTM":"2022-07-17 14:53:24","TRT02EDTM":"2023-07-17 20:53:24","AP01SDTM":"2020-07-17 02:53:24","AP01EDTM":"2022-07-17 14:53:24","AP02SDTM":"2022-07-17 14:53:24","AP02EDTM":"2023-07-17 20:53:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-07-29","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":703,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.10982,"AVALU":"U/L","BASE2":21.9813,"BASE":12.10982,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-9.87148,"PCHG2":-44.90854,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-03 02:53:24","ADY":625,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-244","SUBJID":"id-244","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.26417,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-14","TRTSDTM":"2020-07-17 02:53:24","TRTEDTM":"2023-07-17 20:53:24","TRT01SDTM":"2020-07-17 02:53:24","TRT01EDTM":"2022-07-17 14:53:24","TRT02SDTM":"2022-07-17 14:53:24","TRT02EDTM":"2023-07-17 20:53:24","AP01SDTM":"2020-07-17 02:53:24","AP01EDTM":"2022-07-17 14:53:24","AP02SDTM":"2022-07-17 14:53:24","AP02EDTM":"2023-07-17 20:53:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-07-29","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7485,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.73535,"AVALU":"U/L","BASE2":21.9813,"BASE":12.10982,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.75405,"PCHG2":7.97972,"CHG":11.62553,"PCHG":96.00084,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-15 02:53:24","ADY":759,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-244","SUBJID":"id-244","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.26417,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-14","TRTSDTM":"2020-07-17 02:53:24","TRTEDTM":"2023-07-17 20:53:24","TRT01SDTM":"2020-07-17 02:53:24","TRT01EDTM":"2022-07-17 14:53:24","TRT02SDTM":"2022-07-17 14:53:24","TRT02EDTM":"2023-07-17 20:53:24","AP01SDTM":"2020-07-17 02:53:24","AP01EDTM":"2022-07-17 14:53:24","AP02SDTM":"2022-07-17 14:53:24","AP02EDTM":"2023-07-17 20:53:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-07-29","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3302,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.30212,"AVALU":"U/L","BASE2":21.9813,"BASE":12.10982,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.32082,"PCHG2":15.10746,"CHG":13.1923,"PCHG":108.93885,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-23 02:53:24","ADY":767,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-244","SUBJID":"id-244","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.26417,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-14","TRTSDTM":"2020-07-17 02:53:24","TRTEDTM":"2023-07-17 20:53:24","TRT01SDTM":"2020-07-17 02:53:24","TRT01EDTM":"2022-07-17 14:53:24","TRT02SDTM":"2022-07-17 14:53:24","TRT02EDTM":"2023-07-17 20:53:24","AP01SDTM":"2020-07-17 02:53:24","AP01EDTM":"2022-07-17 14:53:24","AP02SDTM":"2022-07-17 14:53:24","AP02EDTM":"2023-07-17 20:53:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-07-29","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3006,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.7312,"AVALU":"U/L","BASE2":21.9813,"BASE":12.10982,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.2501,"PCHG2":-19.33509,"CHG":5.62138,"PCHG":46.42,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-06 02:53:24","ADY":962,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-244","SUBJID":"id-244","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.26417,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-14","TRTSDTM":"2020-07-17 02:53:24","TRTEDTM":"2023-07-17 20:53:24","TRT01SDTM":"2020-07-17 02:53:24","TRT01EDTM":"2022-07-17 14:53:24","TRT02SDTM":"2022-07-17 14:53:24","TRT02EDTM":"2023-07-17 20:53:24","AP01SDTM":"2020-07-17 02:53:24","AP01EDTM":"2022-07-17 14:53:24","AP02SDTM":"2022-07-17 14:53:24","AP02EDTM":"2023-07-17 20:53:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-07-29","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7287,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.71968,"AVALU":"U/L","BASE2":21.9813,"BASE":12.10982,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.73838,"PCHG2":3.35913,"CHG":10.60986,"PCHG":87.61373,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-14 02:53:24","ADY":970,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-244","SUBJID":"id-244","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.26417,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-14","TRTSDTM":"2020-07-17 02:53:24","TRTEDTM":"2023-07-17 20:53:24","TRT01SDTM":"2020-07-17 02:53:24","TRT01EDTM":"2022-07-17 14:53:24","TRT02SDTM":"2022-07-17 14:53:24","TRT02EDTM":"2023-07-17 20:53:24","AP01SDTM":"2020-07-17 02:53:24","AP01EDTM":"2022-07-17 14:53:24","AP02SDTM":"2022-07-17 14:53:24","AP02EDTM":"2023-07-17 20:53:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-07-29","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3661,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.58506,"AVALU":"U/L","BASE2":21.9813,"BASE":12.10982,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.39624,"PCHG2":-79.14108,"CHG":-7.52476,"PCHG":-62.13765,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2023-06-14 02:53:24","ADY":1062,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-244","SUBJID":"id-244","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.26417,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-14","TRTSDTM":"2020-07-17 02:53:24","TRTEDTM":"2023-07-17 20:53:24","TRT01SDTM":"2020-07-17 02:53:24","TRT01EDTM":"2022-07-17 14:53:24","TRT02SDTM":"2022-07-17 14:53:24","TRT02EDTM":"2023-07-17 20:53:24","AP01SDTM":"2020-07-17 02:53:24","AP01EDTM":"2022-07-17 14:53:24","AP02SDTM":"2022-07-17 14:53:24","AP02EDTM":"2023-07-17 20:53:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-07-29","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5701,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.7704,"AVALU":"mg/L","BASE2":9.7704,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-08 02:53:24","ADY":479,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-244","SUBJID":"id-244","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.26417,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-14","TRTSDTM":"2020-07-17 02:53:24","TRTEDTM":"2023-07-17 20:53:24","TRT01SDTM":"2020-07-17 02:53:24","TRT01EDTM":"2022-07-17 14:53:24","TRT02SDTM":"2022-07-17 14:53:24","TRT02EDTM":"2023-07-17 20:53:24","AP01SDTM":"2020-07-17 02:53:24","AP01EDTM":"2022-07-17 14:53:24","AP02SDTM":"2022-07-17 14:53:24","AP02EDTM":"2023-07-17 20:53:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-07-29","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5100,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.30811,"AVALU":"mg/L","BASE2":9.7704,"BASE":8.30811,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.46229,"PCHG2":-14.9665,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-03 02:53:24","ADY":625,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-244","SUBJID":"id-244","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.26417,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-14","TRTSDTM":"2020-07-17 02:53:24","TRTEDTM":"2023-07-17 20:53:24","TRT01SDTM":"2020-07-17 02:53:24","TRT01EDTM":"2022-07-17 14:53:24","TRT02SDTM":"2022-07-17 14:53:24","TRT02EDTM":"2023-07-17 20:53:24","AP01SDTM":"2020-07-17 02:53:24","AP01EDTM":"2022-07-17 14:53:24","AP02SDTM":"2022-07-17 14:53:24","AP02EDTM":"2023-07-17 20:53:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-07-29","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5127,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.93124,"AVALU":"mg/L","BASE2":9.7704,"BASE":8.30811,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.83915,"PCHG2":-8.58873,"CHG":0.62313,"PCHG":7.50031,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-15 02:53:24","ADY":759,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-244","SUBJID":"id-244","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.26417,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-14","TRTSDTM":"2020-07-17 02:53:24","TRTEDTM":"2023-07-17 20:53:24","TRT01SDTM":"2020-07-17 02:53:24","TRT01EDTM":"2022-07-17 14:53:24","TRT02SDTM":"2022-07-17 14:53:24","TRT02EDTM":"2023-07-17 20:53:24","AP01SDTM":"2020-07-17 02:53:24","AP01EDTM":"2022-07-17 14:53:24","AP02SDTM":"2022-07-17 14:53:24","AP02EDTM":"2023-07-17 20:53:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-07-29","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2521,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.03894,"AVALU":"mg/L","BASE2":9.7704,"BASE":8.30811,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.26855,"PCHG2":12.98358,"CHG":2.73083,"PCHG":32.8695,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-08-23 02:53:24","ADY":767,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-244","SUBJID":"id-244","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.26417,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-14","TRTSDTM":"2020-07-17 02:53:24","TRTEDTM":"2023-07-17 20:53:24","TRT01SDTM":"2020-07-17 02:53:24","TRT01EDTM":"2022-07-17 14:53:24","TRT02SDTM":"2022-07-17 14:53:24","TRT02EDTM":"2023-07-17 20:53:24","AP01SDTM":"2020-07-17 02:53:24","AP01EDTM":"2022-07-17 14:53:24","AP02SDTM":"2022-07-17 14:53:24","AP02EDTM":"2023-07-17 20:53:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-07-29","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3737,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.77688,"AVALU":"mg/L","BASE2":9.7704,"BASE":8.30811,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.99352,"PCHG2":-10.16863,"CHG":0.46877,"PCHG":5.64233,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-06 02:53:24","ADY":962,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-244","SUBJID":"id-244","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.26417,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-14","TRTSDTM":"2020-07-17 02:53:24","TRTEDTM":"2023-07-17 20:53:24","TRT01SDTM":"2020-07-17 02:53:24","TRT01EDTM":"2022-07-17 14:53:24","TRT02SDTM":"2022-07-17 14:53:24","TRT02EDTM":"2023-07-17 20:53:24","AP01SDTM":"2020-07-17 02:53:24","AP01EDTM":"2022-07-17 14:53:24","AP02SDTM":"2022-07-17 14:53:24","AP02EDTM":"2023-07-17 20:53:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-07-29","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5613,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.44574,"AVALU":"mg/L","BASE2":9.7704,"BASE":8.30811,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.32466,"PCHG2":-3.32285,"CHG":1.13763,"PCHG":13.69301,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-14 02:53:24","ADY":970,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-244","SUBJID":"id-244","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.26417,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-14","TRTSDTM":"2020-07-17 02:53:24","TRTEDTM":"2023-07-17 20:53:24","TRT01SDTM":"2020-07-17 02:53:24","TRT01EDTM":"2022-07-17 14:53:24","TRT02SDTM":"2022-07-17 14:53:24","TRT02EDTM":"2023-07-17 20:53:24","AP01SDTM":"2020-07-17 02:53:24","AP01EDTM":"2022-07-17 14:53:24","AP02SDTM":"2022-07-17 14:53:24","AP02EDTM":"2023-07-17 20:53:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-07-29","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":636,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.24452,"AVALU":"mg/L","BASE2":9.7704,"BASE":8.30811,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.52587,"PCHG2":-5.38231,"CHG":0.93641,"PCHG":11.27108,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-14 02:53:24","ADY":1062,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-244","SUBJID":"id-244","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.26417,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-14","TRTSDTM":"2020-07-17 02:53:24","TRTEDTM":"2023-07-17 20:53:24","TRT01SDTM":"2020-07-17 02:53:24","TRT01EDTM":"2022-07-17 14:53:24","TRT02SDTM":"2022-07-17 14:53:24","TRT02EDTM":"2023-07-17 20:53:24","AP01SDTM":"2020-07-17 02:53:24","AP01EDTM":"2022-07-17 14:53:24","AP02SDTM":"2022-07-17 14:53:24","AP02EDTM":"2023-07-17 20:53:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-07-29","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3764,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85162,"AVALU":"g/L","BASE2":2.85162,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-08 02:53:24","ADY":479,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-244","SUBJID":"id-244","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.26417,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-14","TRTSDTM":"2020-07-17 02:53:24","TRTEDTM":"2023-07-17 20:53:24","TRT01SDTM":"2020-07-17 02:53:24","TRT01EDTM":"2022-07-17 14:53:24","TRT02SDTM":"2022-07-17 14:53:24","TRT02EDTM":"2023-07-17 20:53:24","AP01SDTM":"2020-07-17 02:53:24","AP01EDTM":"2022-07-17 14:53:24","AP02SDTM":"2022-07-17 14:53:24","AP02EDTM":"2023-07-17 20:53:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-07-29","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6606,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75759,"AVALU":"g/L","BASE2":2.85162,"BASE":2.75759,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.09403,"PCHG2":-3.29738,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-03 02:53:24","ADY":625,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-244","SUBJID":"id-244","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.26417,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-14","TRTSDTM":"2020-07-17 02:53:24","TRTEDTM":"2023-07-17 20:53:24","TRT01SDTM":"2020-07-17 02:53:24","TRT01EDTM":"2022-07-17 14:53:24","TRT02SDTM":"2022-07-17 14:53:24","TRT02EDTM":"2023-07-17 20:53:24","AP01SDTM":"2020-07-17 02:53:24","AP01EDTM":"2022-07-17 14:53:24","AP02SDTM":"2022-07-17 14:53:24","AP02EDTM":"2023-07-17 20:53:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-07-29","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7922,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.73661,"AVALU":"g/L","BASE2":2.85162,"BASE":2.75759,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11501,"PCHG2":-4.03298,"CHG":-0.02098,"PCHG":-0.76068,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-15 02:53:24","ADY":759,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-244","SUBJID":"id-244","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.26417,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-14","TRTSDTM":"2020-07-17 02:53:24","TRTEDTM":"2023-07-17 20:53:24","TRT01SDTM":"2020-07-17 02:53:24","TRT01EDTM":"2022-07-17 14:53:24","TRT02SDTM":"2022-07-17 14:53:24","TRT02EDTM":"2023-07-17 20:53:24","AP01SDTM":"2020-07-17 02:53:24","AP01EDTM":"2022-07-17 14:53:24","AP02SDTM":"2022-07-17 14:53:24","AP02EDTM":"2023-07-17 20:53:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-07-29","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8163,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85087,"AVALU":"g/L","BASE2":2.85162,"BASE":2.75759,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00075,"PCHG2":-0.02647,"CHG":0.09327,"PCHG":3.38244,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-23 02:53:24","ADY":767,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-244","SUBJID":"id-244","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.26417,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-14","TRTSDTM":"2020-07-17 02:53:24","TRTEDTM":"2023-07-17 20:53:24","TRT01SDTM":"2020-07-17 02:53:24","TRT01EDTM":"2022-07-17 14:53:24","TRT02SDTM":"2022-07-17 14:53:24","TRT02EDTM":"2023-07-17 20:53:24","AP01SDTM":"2020-07-17 02:53:24","AP01EDTM":"2022-07-17 14:53:24","AP02SDTM":"2022-07-17 14:53:24","AP02EDTM":"2023-07-17 20:53:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-07-29","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7907,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89295,"AVALU":"g/L","BASE2":2.85162,"BASE":2.75759,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04133,"PCHG2":1.4495,"CHG":0.13536,"PCHG":4.90874,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-06 02:53:24","ADY":962,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-244","SUBJID":"id-244","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.26417,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-14","TRTSDTM":"2020-07-17 02:53:24","TRTEDTM":"2023-07-17 20:53:24","TRT01SDTM":"2020-07-17 02:53:24","TRT01EDTM":"2022-07-17 14:53:24","TRT02SDTM":"2022-07-17 14:53:24","TRT02EDTM":"2023-07-17 20:53:24","AP01SDTM":"2020-07-17 02:53:24","AP01EDTM":"2022-07-17 14:53:24","AP02SDTM":"2022-07-17 14:53:24","AP02EDTM":"2023-07-17 20:53:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-07-29","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6848,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98059,"AVALU":"g/L","BASE2":2.85162,"BASE":2.75759,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12897,"PCHG2":4.52269,"CHG":0.223,"PCHG":8.08672,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-14 02:53:24","ADY":970,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-244","SUBJID":"id-244","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.26417,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-14","TRTSDTM":"2020-07-17 02:53:24","TRTEDTM":"2023-07-17 20:53:24","TRT01SDTM":"2020-07-17 02:53:24","TRT01EDTM":"2022-07-17 14:53:24","TRT02SDTM":"2022-07-17 14:53:24","TRT02EDTM":"2023-07-17 20:53:24","AP01SDTM":"2020-07-17 02:53:24","AP01EDTM":"2022-07-17 14:53:24","AP02SDTM":"2022-07-17 14:53:24","AP02EDTM":"2023-07-17 20:53:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-17","EOSDY":1096,"LSTALVDT":"2023-07-29","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7464,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87991,"AVALU":"g/L","BASE2":2.85162,"BASE":2.75759,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02829,"PCHG2":0.99204,"CHG":0.12232,"PCHG":4.43568,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-14 02:53:24","ADY":1062,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-246","SUBJID":"id-246","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.11334,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 05:40:20","TRTEDTM":"2023-12-22 23:40:20","TRT01SDTM":"2020-12-22 05:40:20","TRT01EDTM":"2022-12-22 17:40:20","TRT02SDTM":"2022-12-22 17:40:20","TRT02EDTM":"2023-12-22 23:40:20","AP01SDTM":"2020-12-22 05:40:20","AP01EDTM":"2022-12-22 17:40:20","AP02SDTM":"2022-12-22 17:40:20","AP02EDTM":"2023-12-22 23:40:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-08","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3651,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.77914,"AVALU":"U/L","BASE2":20.77914,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-03-21 05:40:20","ADY":89,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-246","SUBJID":"id-246","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.11334,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 05:40:20","TRTEDTM":"2023-12-22 23:40:20","TRT01SDTM":"2020-12-22 05:40:20","TRT01EDTM":"2022-12-22 17:40:20","TRT02SDTM":"2022-12-22 17:40:20","TRT02EDTM":"2023-12-22 23:40:20","AP01SDTM":"2020-12-22 05:40:20","AP01EDTM":"2022-12-22 17:40:20","AP02SDTM":"2022-12-22 17:40:20","AP02EDTM":"2023-12-22 23:40:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-08","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4240,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.53188,"AVALU":"U/L","BASE2":20.77914,"BASE":3.53188,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-17.24726,"PCHG2":-83.00277,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2021-04-10 05:40:20","ADY":109,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-246","SUBJID":"id-246","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.11334,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 05:40:20","TRTEDTM":"2023-12-22 23:40:20","TRT01SDTM":"2020-12-22 05:40:20","TRT01EDTM":"2022-12-22 17:40:20","TRT02SDTM":"2022-12-22 17:40:20","TRT02EDTM":"2023-12-22 23:40:20","AP01SDTM":"2020-12-22 05:40:20","AP01EDTM":"2022-12-22 17:40:20","AP02SDTM":"2022-12-22 17:40:20","AP02EDTM":"2023-12-22 23:40:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-08","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1857,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.49073,"AVALU":"U/L","BASE2":20.77914,"BASE":3.53188,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.28841,"PCHG2":-35.07562,"CHG":9.95885,"PCHG":281.97043,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-10-04 05:40:20","ADY":286,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-246","SUBJID":"id-246","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.11334,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 05:40:20","TRTEDTM":"2023-12-22 23:40:20","TRT01SDTM":"2020-12-22 05:40:20","TRT01EDTM":"2022-12-22 17:40:20","TRT02SDTM":"2022-12-22 17:40:20","TRT02EDTM":"2023-12-22 23:40:20","AP01SDTM":"2020-12-22 05:40:20","AP01EDTM":"2022-12-22 17:40:20","AP02SDTM":"2022-12-22 17:40:20","AP02EDTM":"2023-12-22 23:40:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-08","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8085,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.37995,"AVALU":"U/L","BASE2":20.77914,"BASE":3.53188,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.39919,"PCHG2":-78.92139,"CHG":0.84808,"PCHG":24.01205,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-3","BTOXGR":"-2","ADTM":"2021-10-26 05:40:20","ADY":308,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-246","SUBJID":"id-246","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.11334,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 05:40:20","TRTEDTM":"2023-12-22 23:40:20","TRT01SDTM":"2020-12-22 05:40:20","TRT01EDTM":"2022-12-22 17:40:20","TRT02SDTM":"2022-12-22 17:40:20","TRT02EDTM":"2023-12-22 23:40:20","AP01SDTM":"2020-12-22 05:40:20","AP01EDTM":"2022-12-22 17:40:20","AP02SDTM":"2022-12-22 17:40:20","AP02EDTM":"2023-12-22 23:40:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-08","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":147,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.58369,"AVALU":"U/L","BASE2":20.77914,"BASE":3.53188,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.19546,"PCHG2":-25.00323,"CHG":12.05181,"PCHG":341.22949,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-10-30 05:40:20","ADY":312,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-246","SUBJID":"id-246","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.11334,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 05:40:20","TRTEDTM":"2023-12-22 23:40:20","TRT01SDTM":"2020-12-22 05:40:20","TRT01EDTM":"2022-12-22 17:40:20","TRT02SDTM":"2022-12-22 17:40:20","TRT02EDTM":"2023-12-22 23:40:20","AP01SDTM":"2020-12-22 05:40:20","AP01EDTM":"2022-12-22 17:40:20","AP02SDTM":"2022-12-22 17:40:20","AP02EDTM":"2023-12-22 23:40:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-08","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1606,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.98636,"AVALU":"U/L","BASE2":20.77914,"BASE":3.53188,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.79278,"PCHG2":-47.12792,"CHG":7.45449,"PCHG":211.06298,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2023-02-23 05:40:20","ADY":793,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-246","SUBJID":"id-246","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.11334,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 05:40:20","TRTEDTM":"2023-12-22 23:40:20","TRT01SDTM":"2020-12-22 05:40:20","TRT01EDTM":"2022-12-22 17:40:20","TRT02SDTM":"2022-12-22 17:40:20","TRT02EDTM":"2023-12-22 23:40:20","AP01SDTM":"2020-12-22 05:40:20","AP01EDTM":"2022-12-22 17:40:20","AP02SDTM":"2022-12-22 17:40:20","AP02EDTM":"2023-12-22 23:40:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-08","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6761,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.16348,"AVALU":"U/L","BASE2":20.77914,"BASE":3.53188,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.61566,"PCHG2":-31.838,"CHG":10.6316,"PCHG":301.01839,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2023-05-28 05:40:20","ADY":887,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-246","SUBJID":"id-246","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.11334,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 05:40:20","TRTEDTM":"2023-12-22 23:40:20","TRT01SDTM":"2020-12-22 05:40:20","TRT01EDTM":"2022-12-22 17:40:20","TRT02SDTM":"2022-12-22 17:40:20","TRT02EDTM":"2023-12-22 23:40:20","AP01SDTM":"2020-12-22 05:40:20","AP01EDTM":"2022-12-22 17:40:20","AP02SDTM":"2022-12-22 17:40:20","AP02EDTM":"2023-12-22 23:40:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-08","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3256,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.14907,"AVALU":"mg/L","BASE2":8.14907,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-21 05:40:20","ADY":89,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-246","SUBJID":"id-246","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.11334,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 05:40:20","TRTEDTM":"2023-12-22 23:40:20","TRT01SDTM":"2020-12-22 05:40:20","TRT01EDTM":"2022-12-22 17:40:20","TRT02SDTM":"2022-12-22 17:40:20","TRT02EDTM":"2023-12-22 23:40:20","AP01SDTM":"2020-12-22 05:40:20","AP01EDTM":"2022-12-22 17:40:20","AP02SDTM":"2022-12-22 17:40:20","AP02EDTM":"2023-12-22 23:40:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-08","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2785,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.92851,"AVALU":"mg/L","BASE2":8.14907,"BASE":8.92851,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.77944,"PCHG2":9.56481,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-10 05:40:20","ADY":109,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-246","SUBJID":"id-246","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.11334,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 05:40:20","TRTEDTM":"2023-12-22 23:40:20","TRT01SDTM":"2020-12-22 05:40:20","TRT01EDTM":"2022-12-22 17:40:20","TRT02SDTM":"2022-12-22 17:40:20","TRT02EDTM":"2023-12-22 23:40:20","AP01SDTM":"2020-12-22 05:40:20","AP01EDTM":"2022-12-22 17:40:20","AP02SDTM":"2022-12-22 17:40:20","AP02EDTM":"2023-12-22 23:40:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-08","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2716,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.11352,"AVALU":"mg/L","BASE2":8.14907,"BASE":8.92851,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03555,"PCHG2":-0.43621,"CHG":-0.81499,"PCHG":-9.12795,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-04 05:40:20","ADY":286,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-246","SUBJID":"id-246","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.11334,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 05:40:20","TRTEDTM":"2023-12-22 23:40:20","TRT01SDTM":"2020-12-22 05:40:20","TRT01EDTM":"2022-12-22 17:40:20","TRT02SDTM":"2022-12-22 17:40:20","TRT02EDTM":"2023-12-22 23:40:20","AP01SDTM":"2020-12-22 05:40:20","AP01EDTM":"2022-12-22 17:40:20","AP02SDTM":"2022-12-22 17:40:20","AP02EDTM":"2023-12-22 23:40:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-08","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7661,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.50595,"AVALU":"mg/L","BASE2":8.14907,"BASE":8.92851,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.35688,"PCHG2":28.92205,"CHG":1.57744,"PCHG":17.66739,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2021-10-26 05:40:20","ADY":308,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-246","SUBJID":"id-246","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.11334,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 05:40:20","TRTEDTM":"2023-12-22 23:40:20","TRT01SDTM":"2020-12-22 05:40:20","TRT01EDTM":"2022-12-22 17:40:20","TRT02SDTM":"2022-12-22 17:40:20","TRT02EDTM":"2023-12-22 23:40:20","AP01SDTM":"2020-12-22 05:40:20","AP01EDTM":"2022-12-22 17:40:20","AP02SDTM":"2022-12-22 17:40:20","AP02EDTM":"2023-12-22 23:40:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-08","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7309,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.68809,"AVALU":"mg/L","BASE2":8.14907,"BASE":8.92851,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.53902,"PCHG2":18.88585,"CHG":0.75958,"PCHG":8.50733,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-30 05:40:20","ADY":312,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-246","SUBJID":"id-246","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.11334,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 05:40:20","TRTEDTM":"2023-12-22 23:40:20","TRT01SDTM":"2020-12-22 05:40:20","TRT01EDTM":"2022-12-22 17:40:20","TRT02SDTM":"2022-12-22 17:40:20","TRT02EDTM":"2023-12-22 23:40:20","AP01SDTM":"2020-12-22 05:40:20","AP01EDTM":"2022-12-22 17:40:20","AP02SDTM":"2022-12-22 17:40:20","AP02EDTM":"2023-12-22 23:40:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-08","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":620,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.55784,"AVALU":"mg/L","BASE2":8.14907,"BASE":8.92851,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.40877,"PCHG2":5.01611,"CHG":-0.37068,"PCHG":-4.1516,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-23 05:40:20","ADY":793,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-246","SUBJID":"id-246","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.11334,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 05:40:20","TRTEDTM":"2023-12-22 23:40:20","TRT01SDTM":"2020-12-22 05:40:20","TRT01EDTM":"2022-12-22 17:40:20","TRT02SDTM":"2022-12-22 17:40:20","TRT02EDTM":"2023-12-22 23:40:20","AP01SDTM":"2020-12-22 05:40:20","AP01EDTM":"2022-12-22 17:40:20","AP02SDTM":"2022-12-22 17:40:20","AP02EDTM":"2023-12-22 23:40:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-08","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5476,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.12094,"AVALU":"mg/L","BASE2":8.14907,"BASE":8.92851,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.02813,"PCHG2":-12.61653,"CHG":-1.80757,"PCHG":-20.24495,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2023-05-28 05:40:20","ADY":887,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-246","SUBJID":"id-246","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.11334,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 05:40:20","TRTEDTM":"2023-12-22 23:40:20","TRT01SDTM":"2020-12-22 05:40:20","TRT01EDTM":"2022-12-22 17:40:20","TRT02SDTM":"2022-12-22 17:40:20","TRT02EDTM":"2023-12-22 23:40:20","AP01SDTM":"2020-12-22 05:40:20","AP01EDTM":"2022-12-22 17:40:20","AP02SDTM":"2022-12-22 17:40:20","AP02EDTM":"2023-12-22 23:40:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-08","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3129,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.73339,"AVALU":"g/L","BASE2":2.73339,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-21 05:40:20","ADY":89,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-246","SUBJID":"id-246","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.11334,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 05:40:20","TRTEDTM":"2023-12-22 23:40:20","TRT01SDTM":"2020-12-22 05:40:20","TRT01EDTM":"2022-12-22 17:40:20","TRT02SDTM":"2022-12-22 17:40:20","TRT02EDTM":"2023-12-22 23:40:20","AP01SDTM":"2020-12-22 05:40:20","AP01EDTM":"2022-12-22 17:40:20","AP02SDTM":"2022-12-22 17:40:20","AP02EDTM":"2023-12-22 23:40:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-08","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7253,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.637,"AVALU":"g/L","BASE2":2.73339,"BASE":2.637,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.09639,"PCHG2":-3.52637,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-10 05:40:20","ADY":109,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-246","SUBJID":"id-246","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.11334,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 05:40:20","TRTEDTM":"2023-12-22 23:40:20","TRT01SDTM":"2020-12-22 05:40:20","TRT01EDTM":"2022-12-22 17:40:20","TRT02SDTM":"2022-12-22 17:40:20","TRT02EDTM":"2023-12-22 23:40:20","AP01SDTM":"2020-12-22 05:40:20","AP01EDTM":"2022-12-22 17:40:20","AP02SDTM":"2022-12-22 17:40:20","AP02EDTM":"2023-12-22 23:40:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-08","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":288,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01266,"AVALU":"g/L","BASE2":2.73339,"BASE":2.637,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.27927,"PCHG2":10.21712,"CHG":0.37566,"PCHG":14.24585,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-10-04 05:40:20","ADY":286,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-246","SUBJID":"id-246","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.11334,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 05:40:20","TRTEDTM":"2023-12-22 23:40:20","TRT01SDTM":"2020-12-22 05:40:20","TRT01EDTM":"2022-12-22 17:40:20","TRT02SDTM":"2022-12-22 17:40:20","TRT02EDTM":"2023-12-22 23:40:20","AP01SDTM":"2020-12-22 05:40:20","AP01EDTM":"2022-12-22 17:40:20","AP02SDTM":"2022-12-22 17:40:20","AP02EDTM":"2023-12-22 23:40:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-08","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5527,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92988,"AVALU":"g/L","BASE2":2.73339,"BASE":2.637,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.19649,"PCHG2":7.18857,"CHG":0.29288,"PCHG":11.1066,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-26 05:40:20","ADY":308,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-246","SUBJID":"id-246","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.11334,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 05:40:20","TRTEDTM":"2023-12-22 23:40:20","TRT01SDTM":"2020-12-22 05:40:20","TRT01EDTM":"2022-12-22 17:40:20","TRT02SDTM":"2022-12-22 17:40:20","TRT02EDTM":"2023-12-22 23:40:20","AP01SDTM":"2020-12-22 05:40:20","AP01EDTM":"2022-12-22 17:40:20","AP02SDTM":"2022-12-22 17:40:20","AP02EDTM":"2023-12-22 23:40:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-08","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6739,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02077,"AVALU":"g/L","BASE2":2.73339,"BASE":2.637,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.28738,"PCHG2":10.51358,"CHG":0.38377,"PCHG":14.55315,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-10-30 05:40:20","ADY":312,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-246","SUBJID":"id-246","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.11334,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 05:40:20","TRTEDTM":"2023-12-22 23:40:20","TRT01SDTM":"2020-12-22 05:40:20","TRT01EDTM":"2022-12-22 17:40:20","TRT02SDTM":"2022-12-22 17:40:20","TRT02EDTM":"2023-12-22 23:40:20","AP01SDTM":"2020-12-22 05:40:20","AP01EDTM":"2022-12-22 17:40:20","AP02SDTM":"2022-12-22 17:40:20","AP02EDTM":"2023-12-22 23:40:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-08","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6601,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96565,"AVALU":"g/L","BASE2":2.73339,"BASE":2.637,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.23226,"PCHG2":8.49717,"CHG":0.32865,"PCHG":12.46303,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-23 05:40:20","ADY":793,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-246","SUBJID":"id-246","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.11334,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 05:40:20","TRTEDTM":"2023-12-22 23:40:20","TRT01SDTM":"2020-12-22 05:40:20","TRT01EDTM":"2022-12-22 17:40:20","TRT02SDTM":"2022-12-22 17:40:20","TRT02EDTM":"2023-12-22 23:40:20","AP01SDTM":"2020-12-22 05:40:20","AP01EDTM":"2022-12-22 17:40:20","AP02SDTM":"2022-12-22 17:40:20","AP02EDTM":"2023-12-22 23:40:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-08","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4713,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.71394,"AVALU":"g/L","BASE2":2.73339,"BASE":2.637,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01945,"PCHG2":-0.71144,"CHG":0.07694,"PCHG":2.91782,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-28 05:40:20","ADY":887,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-247","SUBJID":"id-247","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.01895,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-27","TRTSDTM":"2019-07-28 23:48:24","TRTEDTM":"2022-07-28 17:48:24","TRT01SDTM":"2019-07-28 23:48:24","TRT01EDTM":"2021-07-28 11:48:24","TRT02SDTM":"2021-07-28 11:48:24","TRT02EDTM":"2022-07-28 17:48:24","AP01SDTM":"2019-07-28 23:48:24","AP01EDTM":"2021-07-28 11:48:24","AP02SDTM":"2021-07-28 11:48:24","AP02EDTM":"2022-07-28 17:48:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2408,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.46367,"AVALU":"U/L","BASE2":5.46367,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-2","BTOXGR":"0","ADTM":"2019-08-22 23:48:24","ADY":25,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-247","SUBJID":"id-247","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.01895,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-27","TRTSDTM":"2019-07-28 23:48:24","TRTEDTM":"2022-07-28 17:48:24","TRT01SDTM":"2019-07-28 23:48:24","TRT01EDTM":"2021-07-28 11:48:24","TRT02SDTM":"2021-07-28 11:48:24","TRT02EDTM":"2022-07-28 17:48:24","AP01SDTM":"2019-07-28 23:48:24","AP01EDTM":"2021-07-28 11:48:24","AP02SDTM":"2021-07-28 11:48:24","AP02EDTM":"2022-07-28 17:48:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3962,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":38.48818,"AVALU":"U/L","BASE2":5.46367,"BASE":38.48818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":33.02451,"PCHG2":604.43867,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-06 23:48:24","ADY":131,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-247","SUBJID":"id-247","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.01895,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-27","TRTSDTM":"2019-07-28 23:48:24","TRTEDTM":"2022-07-28 17:48:24","TRT01SDTM":"2019-07-28 23:48:24","TRT01EDTM":"2021-07-28 11:48:24","TRT02SDTM":"2021-07-28 11:48:24","TRT02EDTM":"2022-07-28 17:48:24","AP01SDTM":"2019-07-28 23:48:24","AP01EDTM":"2021-07-28 11:48:24","AP02SDTM":"2021-07-28 11:48:24","AP02EDTM":"2022-07-28 17:48:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7081,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.67346,"AVALU":"U/L","BASE2":5.46367,"BASE":38.48818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.20979,"PCHG2":260.07803,"CHG":-18.81471,"PCHG":-48.8844,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-25 23:48:24","ADY":212,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-247","SUBJID":"id-247","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.01895,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-27","TRTSDTM":"2019-07-28 23:48:24","TRTEDTM":"2022-07-28 17:48:24","TRT01SDTM":"2019-07-28 23:48:24","TRT01EDTM":"2021-07-28 11:48:24","TRT02SDTM":"2021-07-28 11:48:24","TRT02EDTM":"2022-07-28 17:48:24","AP01SDTM":"2019-07-28 23:48:24","AP01EDTM":"2021-07-28 11:48:24","AP02SDTM":"2021-07-28 11:48:24","AP02EDTM":"2022-07-28 17:48:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3383,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.92739,"AVALU":"U/L","BASE2":5.46367,"BASE":38.48818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.46372,"PCHG2":356.2392,"CHG":-13.56079,"PCHG":-35.23365,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-15 23:48:24","ADY":506,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-247","SUBJID":"id-247","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.01895,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-27","TRTSDTM":"2019-07-28 23:48:24","TRTEDTM":"2022-07-28 17:48:24","TRT01SDTM":"2019-07-28 23:48:24","TRT01EDTM":"2021-07-28 11:48:24","TRT02SDTM":"2021-07-28 11:48:24","TRT02EDTM":"2022-07-28 17:48:24","AP01SDTM":"2019-07-28 23:48:24","AP01EDTM":"2021-07-28 11:48:24","AP02SDTM":"2021-07-28 11:48:24","AP02EDTM":"2022-07-28 17:48:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5731,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.82219,"AVALU":"U/L","BASE2":5.46367,"BASE":38.48818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.35853,"PCHG2":171.28657,"CHG":-23.66598,"PCHG":-61.48897,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-22 23:48:24","ADY":513,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-247","SUBJID":"id-247","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.01895,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-27","TRTSDTM":"2019-07-28 23:48:24","TRTEDTM":"2022-07-28 17:48:24","TRT01SDTM":"2019-07-28 23:48:24","TRT01EDTM":"2021-07-28 11:48:24","TRT02SDTM":"2021-07-28 11:48:24","TRT02EDTM":"2022-07-28 17:48:24","AP01SDTM":"2019-07-28 23:48:24","AP01EDTM":"2021-07-28 11:48:24","AP02SDTM":"2021-07-28 11:48:24","AP02EDTM":"2022-07-28 17:48:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2422,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.66824,"AVALU":"U/L","BASE2":5.46367,"BASE":38.48818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.20457,"PCHG2":40.34973,"CHG":-30.81994,"PCHG":-80.07637,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-08 23:48:24","ADY":530,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-247","SUBJID":"id-247","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.01895,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-27","TRTSDTM":"2019-07-28 23:48:24","TRTEDTM":"2022-07-28 17:48:24","TRT01SDTM":"2019-07-28 23:48:24","TRT01EDTM":"2021-07-28 11:48:24","TRT02SDTM":"2021-07-28 11:48:24","TRT02EDTM":"2022-07-28 17:48:24","AP01SDTM":"2019-07-28 23:48:24","AP01EDTM":"2021-07-28 11:48:24","AP02SDTM":"2021-07-28 11:48:24","AP02EDTM":"2022-07-28 17:48:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":566,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.88724,"AVALU":"U/L","BASE2":5.46367,"BASE":38.48818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.57643,"PCHG2":-65.45838,"CHG":-36.60094,"PCHG":-95.09658,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-11-13 23:48:24","ADY":839,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-247","SUBJID":"id-247","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.01895,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-27","TRTSDTM":"2019-07-28 23:48:24","TRTEDTM":"2022-07-28 17:48:24","TRT01SDTM":"2019-07-28 23:48:24","TRT01EDTM":"2021-07-28 11:48:24","TRT02SDTM":"2021-07-28 11:48:24","TRT02EDTM":"2022-07-28 17:48:24","AP01SDTM":"2019-07-28 23:48:24","AP01EDTM":"2021-07-28 11:48:24","AP02SDTM":"2021-07-28 11:48:24","AP02EDTM":"2022-07-28 17:48:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4551,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.00554,"AVALU":"mg/L","BASE2":10.00554,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"1","ADTM":"2019-08-22 23:48:24","ADY":25,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-247","SUBJID":"id-247","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.01895,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-27","TRTSDTM":"2019-07-28 23:48:24","TRTEDTM":"2022-07-28 17:48:24","TRT01SDTM":"2019-07-28 23:48:24","TRT01EDTM":"2021-07-28 11:48:24","TRT02SDTM":"2021-07-28 11:48:24","TRT02EDTM":"2022-07-28 17:48:24","AP01SDTM":"2019-07-28 23:48:24","AP01EDTM":"2021-07-28 11:48:24","AP02SDTM":"2021-07-28 11:48:24","AP02EDTM":"2022-07-28 17:48:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2013,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.11234,"AVALU":"mg/L","BASE2":10.00554,"BASE":10.11234,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.1068,"PCHG2":1.06741,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2019-12-06 23:48:24","ADY":131,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-247","SUBJID":"id-247","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.01895,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-27","TRTSDTM":"2019-07-28 23:48:24","TRTEDTM":"2022-07-28 17:48:24","TRT01SDTM":"2019-07-28 23:48:24","TRT01EDTM":"2021-07-28 11:48:24","TRT02SDTM":"2021-07-28 11:48:24","TRT02EDTM":"2022-07-28 17:48:24","AP01SDTM":"2019-07-28 23:48:24","AP01EDTM":"2021-07-28 11:48:24","AP02SDTM":"2021-07-28 11:48:24","AP02EDTM":"2022-07-28 17:48:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7903,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.15677,"AVALU":"mg/L","BASE2":10.00554,"BASE":10.11234,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.15123,"PCHG2":11.50595,"CHG":1.04443,"PCHG":10.32829,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"1","ADTM":"2020-02-25 23:48:24","ADY":212,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-247","SUBJID":"id-247","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.01895,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-27","TRTSDTM":"2019-07-28 23:48:24","TRTEDTM":"2022-07-28 17:48:24","TRT01SDTM":"2019-07-28 23:48:24","TRT01EDTM":"2021-07-28 11:48:24","TRT02SDTM":"2021-07-28 11:48:24","TRT02EDTM":"2022-07-28 17:48:24","AP01SDTM":"2019-07-28 23:48:24","AP01EDTM":"2021-07-28 11:48:24","AP02SDTM":"2021-07-28 11:48:24","AP02EDTM":"2022-07-28 17:48:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7530,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.59218,"AVALU":"mg/L","BASE2":10.00554,"BASE":10.11234,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.41336,"PCHG2":-14.12579,"CHG":-1.52016,"PCHG":-15.03274,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-12-15 23:48:24","ADY":506,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-247","SUBJID":"id-247","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.01895,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-27","TRTSDTM":"2019-07-28 23:48:24","TRTEDTM":"2022-07-28 17:48:24","TRT01SDTM":"2019-07-28 23:48:24","TRT01EDTM":"2021-07-28 11:48:24","TRT02SDTM":"2021-07-28 11:48:24","TRT02EDTM":"2022-07-28 17:48:24","AP01SDTM":"2019-07-28 23:48:24","AP01EDTM":"2021-07-28 11:48:24","AP02SDTM":"2021-07-28 11:48:24","AP02EDTM":"2022-07-28 17:48:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7150,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.5421,"AVALU":"mg/L","BASE2":10.00554,"BASE":10.11234,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.46344,"PCHG2":-14.62625,"CHG":-1.57024,"PCHG":-15.52792,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-12-22 23:48:24","ADY":513,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-247","SUBJID":"id-247","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.01895,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-27","TRTSDTM":"2019-07-28 23:48:24","TRTEDTM":"2022-07-28 17:48:24","TRT01SDTM":"2019-07-28 23:48:24","TRT01EDTM":"2021-07-28 11:48:24","TRT02SDTM":"2021-07-28 11:48:24","TRT02EDTM":"2022-07-28 17:48:24","AP01SDTM":"2019-07-28 23:48:24","AP01EDTM":"2021-07-28 11:48:24","AP02SDTM":"2021-07-28 11:48:24","AP02EDTM":"2022-07-28 17:48:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1947,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.44461,"AVALU":"mg/L","BASE2":10.00554,"BASE":10.11234,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.56093,"PCHG2":-25.59513,"CHG":-2.66773,"PCHG":-26.38095,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-4","BTOXGR":"1","ADTM":"2021-01-08 23:48:24","ADY":530,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-247","SUBJID":"id-247","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.01895,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-27","TRTSDTM":"2019-07-28 23:48:24","TRTEDTM":"2022-07-28 17:48:24","TRT01SDTM":"2019-07-28 23:48:24","TRT01EDTM":"2021-07-28 11:48:24","TRT02SDTM":"2021-07-28 11:48:24","TRT02EDTM":"2022-07-28 17:48:24","AP01SDTM":"2019-07-28 23:48:24","AP01EDTM":"2021-07-28 11:48:24","AP02SDTM":"2021-07-28 11:48:24","AP02EDTM":"2022-07-28 17:48:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6404,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.54011,"AVALU":"mg/L","BASE2":10.00554,"BASE":10.11234,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.46543,"PCHG2":-4.65171,"CHG":-0.57223,"PCHG":-5.65872,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-11-13 23:48:24","ADY":839,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-247","SUBJID":"id-247","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.01895,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-27","TRTSDTM":"2019-07-28 23:48:24","TRTEDTM":"2022-07-28 17:48:24","TRT01SDTM":"2019-07-28 23:48:24","TRT01EDTM":"2021-07-28 11:48:24","TRT02SDTM":"2021-07-28 11:48:24","TRT02EDTM":"2022-07-28 17:48:24","AP01SDTM":"2019-07-28 23:48:24","AP01EDTM":"2021-07-28 11:48:24","AP02SDTM":"2021-07-28 11:48:24","AP02EDTM":"2022-07-28 17:48:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6280,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86751,"AVALU":"g/L","BASE2":2.86751,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-22 23:48:24","ADY":25,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-247","SUBJID":"id-247","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.01895,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-27","TRTSDTM":"2019-07-28 23:48:24","TRTEDTM":"2022-07-28 17:48:24","TRT01SDTM":"2019-07-28 23:48:24","TRT01EDTM":"2021-07-28 11:48:24","TRT02SDTM":"2021-07-28 11:48:24","TRT02EDTM":"2022-07-28 17:48:24","AP01SDTM":"2019-07-28 23:48:24","AP01EDTM":"2021-07-28 11:48:24","AP02SDTM":"2021-07-28 11:48:24","AP02EDTM":"2022-07-28 17:48:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3671,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93339,"AVALU":"g/L","BASE2":2.86751,"BASE":2.93339,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.06588,"PCHG2":2.29746,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-06 23:48:24","ADY":131,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-247","SUBJID":"id-247","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.01895,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-27","TRTSDTM":"2019-07-28 23:48:24","TRTEDTM":"2022-07-28 17:48:24","TRT01SDTM":"2019-07-28 23:48:24","TRT01EDTM":"2021-07-28 11:48:24","TRT02SDTM":"2021-07-28 11:48:24","TRT02EDTM":"2022-07-28 17:48:24","AP01SDTM":"2019-07-28 23:48:24","AP01EDTM":"2021-07-28 11:48:24","AP02SDTM":"2021-07-28 11:48:24","AP02EDTM":"2022-07-28 17:48:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6615,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79645,"AVALU":"g/L","BASE2":2.86751,"BASE":2.93339,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07106,"PCHG2":-2.47802,"CHG":-0.13694,"PCHG":-4.66823,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-25 23:48:24","ADY":212,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-247","SUBJID":"id-247","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.01895,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-27","TRTSDTM":"2019-07-28 23:48:24","TRTEDTM":"2022-07-28 17:48:24","TRT01SDTM":"2019-07-28 23:48:24","TRT01EDTM":"2021-07-28 11:48:24","TRT02SDTM":"2021-07-28 11:48:24","TRT02EDTM":"2022-07-28 17:48:24","AP01SDTM":"2019-07-28 23:48:24","AP01EDTM":"2021-07-28 11:48:24","AP02SDTM":"2021-07-28 11:48:24","AP02EDTM":"2022-07-28 17:48:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3518,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92759,"AVALU":"g/L","BASE2":2.86751,"BASE":2.93339,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06009,"PCHG2":2.09544,"CHG":-0.00579,"PCHG":-0.19749,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-15 23:48:24","ADY":506,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-247","SUBJID":"id-247","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.01895,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-27","TRTSDTM":"2019-07-28 23:48:24","TRTEDTM":"2022-07-28 17:48:24","TRT01SDTM":"2019-07-28 23:48:24","TRT01EDTM":"2021-07-28 11:48:24","TRT02SDTM":"2021-07-28 11:48:24","TRT02EDTM":"2022-07-28 17:48:24","AP01SDTM":"2019-07-28 23:48:24","AP01EDTM":"2021-07-28 11:48:24","AP02SDTM":"2021-07-28 11:48:24","AP02EDTM":"2022-07-28 17:48:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6274,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85384,"AVALU":"g/L","BASE2":2.86751,"BASE":2.93339,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01367,"PCHG2":-0.47667,"CHG":-0.07955,"PCHG":-2.71183,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-22 23:48:24","ADY":513,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-247","SUBJID":"id-247","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.01895,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-27","TRTSDTM":"2019-07-28 23:48:24","TRTEDTM":"2022-07-28 17:48:24","TRT01SDTM":"2019-07-28 23:48:24","TRT01EDTM":"2021-07-28 11:48:24","TRT02SDTM":"2021-07-28 11:48:24","TRT02EDTM":"2022-07-28 17:48:24","AP01SDTM":"2019-07-28 23:48:24","AP01EDTM":"2021-07-28 11:48:24","AP02SDTM":"2021-07-28 11:48:24","AP02EDTM":"2022-07-28 17:48:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3325,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01497,"AVALU":"g/L","BASE2":2.86751,"BASE":2.93339,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14746,"PCHG2":5.14261,"CHG":0.08158,"PCHG":2.78124,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-01-08 23:48:24","ADY":530,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-247","SUBJID":"id-247","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.01895,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-27","TRTSDTM":"2019-07-28 23:48:24","TRTEDTM":"2022-07-28 17:48:24","TRT01SDTM":"2019-07-28 23:48:24","TRT01EDTM":"2021-07-28 11:48:24","TRT02SDTM":"2021-07-28 11:48:24","TRT02EDTM":"2022-07-28 17:48:24","AP01SDTM":"2019-07-28 23:48:24","AP01EDTM":"2021-07-28 11:48:24","AP02SDTM":"2021-07-28 11:48:24","AP02EDTM":"2022-07-28 17:48:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":447,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94946,"AVALU":"g/L","BASE2":2.86751,"BASE":2.93339,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08196,"PCHG2":2.8582,"CHG":0.01608,"PCHG":0.54814,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-13 23:48:24","ADY":839,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-256","SUBJID":"id-256","SITEID":"CHN-11","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.65204,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-14","TRTSDTM":"2020-03-17 00:36:00","TRTEDTM":"2023-03-17 18:36:00","TRT01SDTM":"2020-03-17 00:36:00","TRT01EDTM":"2022-03-17 12:36:00","TRT02SDTM":"2022-03-17 12:36:00","TRT02EDTM":"2023-03-17 18:36:00","AP01SDTM":"2020-03-17 00:36:00","AP01EDTM":"2022-03-17 12:36:00","AP02SDTM":"2022-03-17 12:36:00","AP02EDTM":"2023-03-17 18:36:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-17","EOSDY":1096,"LSTALVDT":"2023-03-27","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.59031,"AVALU":"U/L","BASE2":14.59031,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-22 00:36:00","ADY":36,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-256","SUBJID":"id-256","SITEID":"CHN-11","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.65204,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-14","TRTSDTM":"2020-03-17 00:36:00","TRTEDTM":"2023-03-17 18:36:00","TRT01SDTM":"2020-03-17 00:36:00","TRT01EDTM":"2022-03-17 12:36:00","TRT02SDTM":"2022-03-17 12:36:00","TRT02EDTM":"2023-03-17 18:36:00","AP01SDTM":"2020-03-17 00:36:00","AP01EDTM":"2022-03-17 12:36:00","AP02SDTM":"2022-03-17 12:36:00","AP02EDTM":"2023-03-17 18:36:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-17","EOSDY":1096,"LSTALVDT":"2023-03-27","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2817,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":38.42899,"AVALU":"U/L","BASE2":14.59031,"BASE":38.42899,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":23.83868,"PCHG2":163.387,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-22 00:36:00","ADY":584,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-256","SUBJID":"id-256","SITEID":"CHN-11","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.65204,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-14","TRTSDTM":"2020-03-17 00:36:00","TRTEDTM":"2023-03-17 18:36:00","TRT01SDTM":"2020-03-17 00:36:00","TRT01EDTM":"2022-03-17 12:36:00","TRT02SDTM":"2022-03-17 12:36:00","TRT02EDTM":"2023-03-17 18:36:00","AP01SDTM":"2020-03-17 00:36:00","AP01EDTM":"2022-03-17 12:36:00","AP02SDTM":"2022-03-17 12:36:00","AP02EDTM":"2023-03-17 18:36:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-17","EOSDY":1096,"LSTALVDT":"2023-03-27","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3081,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.27037,"AVALU":"U/L","BASE2":14.59031,"BASE":38.42899,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.68006,"PCHG2":32.07646,"CHG":-19.15862,"PCHG":-49.8546,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-19 00:36:00","ADY":704,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-256","SUBJID":"id-256","SITEID":"CHN-11","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.65204,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-14","TRTSDTM":"2020-03-17 00:36:00","TRTEDTM":"2023-03-17 18:36:00","TRT01SDTM":"2020-03-17 00:36:00","TRT01EDTM":"2022-03-17 12:36:00","TRT02SDTM":"2022-03-17 12:36:00","TRT02EDTM":"2023-03-17 18:36:00","AP01SDTM":"2020-03-17 00:36:00","AP01EDTM":"2022-03-17 12:36:00","AP02SDTM":"2022-03-17 12:36:00","AP02EDTM":"2023-03-17 18:36:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-17","EOSDY":1096,"LSTALVDT":"2023-03-27","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1182,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":41.98855,"AVALU":"U/L","BASE2":14.59031,"BASE":38.42899,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":27.39823,"PCHG2":187.78372,"CHG":3.55956,"PCHG":9.26269,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-28 00:36:00","ADY":741,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-256","SUBJID":"id-256","SITEID":"CHN-11","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.65204,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-14","TRTSDTM":"2020-03-17 00:36:00","TRTEDTM":"2023-03-17 18:36:00","TRT01SDTM":"2020-03-17 00:36:00","TRT01EDTM":"2022-03-17 12:36:00","TRT02SDTM":"2022-03-17 12:36:00","TRT02EDTM":"2023-03-17 18:36:00","AP01SDTM":"2020-03-17 00:36:00","AP01EDTM":"2022-03-17 12:36:00","AP02SDTM":"2022-03-17 12:36:00","AP02EDTM":"2023-03-17 18:36:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-17","EOSDY":1096,"LSTALVDT":"2023-03-27","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3600,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.74779,"AVALU":"U/L","BASE2":14.59031,"BASE":38.42899,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.15747,"PCHG2":55.91021,"CHG":-15.6812,"PCHG":-40.80566,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-03 00:36:00","ADY":808,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-256","SUBJID":"id-256","SITEID":"CHN-11","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.65204,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-14","TRTSDTM":"2020-03-17 00:36:00","TRTEDTM":"2023-03-17 18:36:00","TRT01SDTM":"2020-03-17 00:36:00","TRT01EDTM":"2022-03-17 12:36:00","TRT02SDTM":"2022-03-17 12:36:00","TRT02EDTM":"2023-03-17 18:36:00","AP01SDTM":"2020-03-17 00:36:00","AP01EDTM":"2022-03-17 12:36:00","AP02SDTM":"2022-03-17 12:36:00","AP02EDTM":"2023-03-17 18:36:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-17","EOSDY":1096,"LSTALVDT":"2023-03-27","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7066,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.37108,"AVALU":"U/L","BASE2":14.59031,"BASE":38.42899,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.21924,"PCHG2":-35.77192,"CHG":-29.05791,"PCHG":-75.61456,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-31 00:36:00","ADY":897,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-256","SUBJID":"id-256","SITEID":"CHN-11","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.65204,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-14","TRTSDTM":"2020-03-17 00:36:00","TRTEDTM":"2023-03-17 18:36:00","TRT01SDTM":"2020-03-17 00:36:00","TRT01EDTM":"2022-03-17 12:36:00","TRT02SDTM":"2022-03-17 12:36:00","TRT02EDTM":"2023-03-17 18:36:00","AP01SDTM":"2020-03-17 00:36:00","AP01EDTM":"2022-03-17 12:36:00","AP02SDTM":"2022-03-17 12:36:00","AP02EDTM":"2023-03-17 18:36:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-17","EOSDY":1096,"LSTALVDT":"2023-03-27","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1392,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.60222,"AVALU":"U/L","BASE2":14.59031,"BASE":38.42899,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.01191,"PCHG2":41.2048,"CHG":-17.82677,"PCHG":-46.38885,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-08 00:36:00","ADY":1086,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-256","SUBJID":"id-256","SITEID":"CHN-11","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.65204,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-14","TRTSDTM":"2020-03-17 00:36:00","TRTEDTM":"2023-03-17 18:36:00","TRT01SDTM":"2020-03-17 00:36:00","TRT01EDTM":"2022-03-17 12:36:00","TRT02SDTM":"2022-03-17 12:36:00","TRT02EDTM":"2023-03-17 18:36:00","AP01SDTM":"2020-03-17 00:36:00","AP01EDTM":"2022-03-17 12:36:00","AP02SDTM":"2022-03-17 12:36:00","AP02EDTM":"2023-03-17 18:36:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-17","EOSDY":1096,"LSTALVDT":"2023-03-27","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4915,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.21021,"AVALU":"mg/L","BASE2":9.21021,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-22 00:36:00","ADY":36,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-256","SUBJID":"id-256","SITEID":"CHN-11","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.65204,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-14","TRTSDTM":"2020-03-17 00:36:00","TRTEDTM":"2023-03-17 18:36:00","TRT01SDTM":"2020-03-17 00:36:00","TRT01EDTM":"2022-03-17 12:36:00","TRT02SDTM":"2022-03-17 12:36:00","TRT02EDTM":"2023-03-17 18:36:00","AP01SDTM":"2020-03-17 00:36:00","AP01EDTM":"2022-03-17 12:36:00","AP02SDTM":"2022-03-17 12:36:00","AP02EDTM":"2023-03-17 18:36:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-17","EOSDY":1096,"LSTALVDT":"2023-03-27","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2385,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.91963,"AVALU":"mg/L","BASE2":9.21021,"BASE":8.91963,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.29058,"PCHG2":-3.15493,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-22 00:36:00","ADY":584,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-256","SUBJID":"id-256","SITEID":"CHN-11","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.65204,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-14","TRTSDTM":"2020-03-17 00:36:00","TRTEDTM":"2023-03-17 18:36:00","TRT01SDTM":"2020-03-17 00:36:00","TRT01EDTM":"2022-03-17 12:36:00","TRT02SDTM":"2022-03-17 12:36:00","TRT02EDTM":"2023-03-17 18:36:00","AP01SDTM":"2020-03-17 00:36:00","AP01EDTM":"2022-03-17 12:36:00","AP02SDTM":"2022-03-17 12:36:00","AP02EDTM":"2023-03-17 18:36:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-17","EOSDY":1096,"LSTALVDT":"2023-03-27","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":808,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.36958,"AVALU":"mg/L","BASE2":9.21021,"BASE":8.91963,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.84063,"PCHG2":-30.84222,"CHG":-2.55006,"PCHG":-28.58926,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-02-19 00:36:00","ADY":704,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-256","SUBJID":"id-256","SITEID":"CHN-11","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.65204,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-14","TRTSDTM":"2020-03-17 00:36:00","TRTEDTM":"2023-03-17 18:36:00","TRT01SDTM":"2020-03-17 00:36:00","TRT01EDTM":"2022-03-17 12:36:00","TRT02SDTM":"2022-03-17 12:36:00","TRT02EDTM":"2023-03-17 18:36:00","AP01SDTM":"2020-03-17 00:36:00","AP01EDTM":"2022-03-17 12:36:00","AP02SDTM":"2022-03-17 12:36:00","AP02EDTM":"2023-03-17 18:36:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-17","EOSDY":1096,"LSTALVDT":"2023-03-27","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3733,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.9546,"AVALU":"mg/L","BASE2":9.21021,"BASE":8.91963,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.25561,"PCHG2":-24.49034,"CHG":-1.96504,"PCHG":-22.03046,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-03-28 00:36:00","ADY":741,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-256","SUBJID":"id-256","SITEID":"CHN-11","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.65204,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-14","TRTSDTM":"2020-03-17 00:36:00","TRTEDTM":"2023-03-17 18:36:00","TRT01SDTM":"2020-03-17 00:36:00","TRT01EDTM":"2022-03-17 12:36:00","TRT02SDTM":"2022-03-17 12:36:00","TRT02EDTM":"2023-03-17 18:36:00","AP01SDTM":"2020-03-17 00:36:00","AP01EDTM":"2022-03-17 12:36:00","AP02SDTM":"2022-03-17 12:36:00","AP02EDTM":"2023-03-17 18:36:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-17","EOSDY":1096,"LSTALVDT":"2023-03-27","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8398,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.16146,"AVALU":"mg/L","BASE2":9.21021,"BASE":8.91963,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04875,"PCHG2":-0.52933,"CHG":0.24182,"PCHG":2.71113,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-03 00:36:00","ADY":808,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-256","SUBJID":"id-256","SITEID":"CHN-11","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.65204,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-14","TRTSDTM":"2020-03-17 00:36:00","TRTEDTM":"2023-03-17 18:36:00","TRT01SDTM":"2020-03-17 00:36:00","TRT01EDTM":"2022-03-17 12:36:00","TRT02SDTM":"2022-03-17 12:36:00","TRT02EDTM":"2023-03-17 18:36:00","AP01SDTM":"2020-03-17 00:36:00","AP01EDTM":"2022-03-17 12:36:00","AP02SDTM":"2022-03-17 12:36:00","AP02EDTM":"2023-03-17 18:36:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-17","EOSDY":1096,"LSTALVDT":"2023-03-27","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8352,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.09909,"AVALU":"mg/L","BASE2":9.21021,"BASE":8.91963,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.11112,"PCHG2":-12.06398,"CHG":-0.82054,"PCHG":-9.19928,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-31 00:36:00","ADY":897,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-256","SUBJID":"id-256","SITEID":"CHN-11","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.65204,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-14","TRTSDTM":"2020-03-17 00:36:00","TRTEDTM":"2023-03-17 18:36:00","TRT01SDTM":"2020-03-17 00:36:00","TRT01EDTM":"2022-03-17 12:36:00","TRT02SDTM":"2022-03-17 12:36:00","TRT02EDTM":"2023-03-17 18:36:00","AP01SDTM":"2020-03-17 00:36:00","AP01EDTM":"2022-03-17 12:36:00","AP02SDTM":"2022-03-17 12:36:00","AP02EDTM":"2023-03-17 18:36:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-17","EOSDY":1096,"LSTALVDT":"2023-03-27","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2726,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.74546,"AVALU":"mg/L","BASE2":9.21021,"BASE":8.91963,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.53525,"PCHG2":5.81148,"CHG":0.82583,"PCHG":9.25851,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-08 00:36:00","ADY":1086,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-256","SUBJID":"id-256","SITEID":"CHN-11","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.65204,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-14","TRTSDTM":"2020-03-17 00:36:00","TRTEDTM":"2023-03-17 18:36:00","TRT01SDTM":"2020-03-17 00:36:00","TRT01EDTM":"2022-03-17 12:36:00","TRT02SDTM":"2022-03-17 12:36:00","TRT02EDTM":"2023-03-17 18:36:00","AP01SDTM":"2020-03-17 00:36:00","AP01EDTM":"2022-03-17 12:36:00","AP02SDTM":"2022-03-17 12:36:00","AP02EDTM":"2023-03-17 18:36:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-17","EOSDY":1096,"LSTALVDT":"2023-03-27","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1813,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.71148,"AVALU":"g/L","BASE2":2.71148,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-22 00:36:00","ADY":36,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-256","SUBJID":"id-256","SITEID":"CHN-11","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.65204,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-14","TRTSDTM":"2020-03-17 00:36:00","TRTEDTM":"2023-03-17 18:36:00","TRT01SDTM":"2020-03-17 00:36:00","TRT01EDTM":"2022-03-17 12:36:00","TRT02SDTM":"2022-03-17 12:36:00","TRT02EDTM":"2023-03-17 18:36:00","AP01SDTM":"2020-03-17 00:36:00","AP01EDTM":"2022-03-17 12:36:00","AP02SDTM":"2022-03-17 12:36:00","AP02EDTM":"2023-03-17 18:36:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-17","EOSDY":1096,"LSTALVDT":"2023-03-27","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5579,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98392,"AVALU":"g/L","BASE2":2.71148,"BASE":2.98392,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.27244,"PCHG2":10.04772,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-22 00:36:00","ADY":584,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-256","SUBJID":"id-256","SITEID":"CHN-11","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.65204,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-14","TRTSDTM":"2020-03-17 00:36:00","TRTEDTM":"2023-03-17 18:36:00","TRT01SDTM":"2020-03-17 00:36:00","TRT01EDTM":"2022-03-17 12:36:00","TRT02SDTM":"2022-03-17 12:36:00","TRT02EDTM":"2023-03-17 18:36:00","AP01SDTM":"2020-03-17 00:36:00","AP01EDTM":"2022-03-17 12:36:00","AP02SDTM":"2022-03-17 12:36:00","AP02EDTM":"2023-03-17 18:36:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-17","EOSDY":1096,"LSTALVDT":"2023-03-27","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6983,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95977,"AVALU":"g/L","BASE2":2.71148,"BASE":2.98392,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.24829,"PCHG2":9.15683,"CHG":-0.02416,"PCHG":-0.80955,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-19 00:36:00","ADY":704,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-256","SUBJID":"id-256","SITEID":"CHN-11","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.65204,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-14","TRTSDTM":"2020-03-17 00:36:00","TRTEDTM":"2023-03-17 18:36:00","TRT01SDTM":"2020-03-17 00:36:00","TRT01EDTM":"2022-03-17 12:36:00","TRT02SDTM":"2022-03-17 12:36:00","TRT02EDTM":"2023-03-17 18:36:00","AP01SDTM":"2020-03-17 00:36:00","AP01EDTM":"2022-03-17 12:36:00","AP02SDTM":"2022-03-17 12:36:00","AP02EDTM":"2023-03-17 18:36:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-17","EOSDY":1096,"LSTALVDT":"2023-03-27","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5572,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.73084,"AVALU":"g/L","BASE2":2.71148,"BASE":2.98392,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01936,"PCHG2":0.71404,"CHG":-0.25308,"PCHG":-8.48148,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-28 00:36:00","ADY":741,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-256","SUBJID":"id-256","SITEID":"CHN-11","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.65204,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-14","TRTSDTM":"2020-03-17 00:36:00","TRTEDTM":"2023-03-17 18:36:00","TRT01SDTM":"2020-03-17 00:36:00","TRT01EDTM":"2022-03-17 12:36:00","TRT02SDTM":"2022-03-17 12:36:00","TRT02EDTM":"2023-03-17 18:36:00","AP01SDTM":"2020-03-17 00:36:00","AP01EDTM":"2022-03-17 12:36:00","AP02SDTM":"2022-03-17 12:36:00","AP02EDTM":"2023-03-17 18:36:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-17","EOSDY":1096,"LSTALVDT":"2023-03-27","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1187,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96562,"AVALU":"g/L","BASE2":2.71148,"BASE":2.98392,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.25413,"PCHG2":9.3725,"CHG":-0.01831,"PCHG":-0.61356,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-03 00:36:00","ADY":808,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-256","SUBJID":"id-256","SITEID":"CHN-11","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.65204,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-14","TRTSDTM":"2020-03-17 00:36:00","TRTEDTM":"2023-03-17 18:36:00","TRT01SDTM":"2020-03-17 00:36:00","TRT01EDTM":"2022-03-17 12:36:00","TRT02SDTM":"2022-03-17 12:36:00","TRT02EDTM":"2023-03-17 18:36:00","AP01SDTM":"2020-03-17 00:36:00","AP01EDTM":"2022-03-17 12:36:00","AP02SDTM":"2022-03-17 12:36:00","AP02EDTM":"2023-03-17 18:36:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-17","EOSDY":1096,"LSTALVDT":"2023-03-27","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5262,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.717,"AVALU":"g/L","BASE2":2.71148,"BASE":2.98392,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00552,"PCHG2":0.2034,"CHG":-0.26693,"PCHG":-8.9455,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-31 00:36:00","ADY":897,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-256","SUBJID":"id-256","SITEID":"CHN-11","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.65204,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-14","TRTSDTM":"2020-03-17 00:36:00","TRTEDTM":"2023-03-17 18:36:00","TRT01SDTM":"2020-03-17 00:36:00","TRT01EDTM":"2022-03-17 12:36:00","TRT02SDTM":"2022-03-17 12:36:00","TRT02EDTM":"2023-03-17 18:36:00","AP01SDTM":"2020-03-17 00:36:00","AP01EDTM":"2022-03-17 12:36:00","AP02SDTM":"2022-03-17 12:36:00","AP02EDTM":"2023-03-17 18:36:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-17","EOSDY":1096,"LSTALVDT":"2023-03-27","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6689,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92407,"AVALU":"g/L","BASE2":2.71148,"BASE":2.98392,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.21259,"PCHG2":7.84042,"CHG":-0.05985,"PCHG":-2.00576,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-08 00:36:00","ADY":1086,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-257","SUBJID":"id-257","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.83771,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-15","TRTSDTM":"2020-11-15 17:38:32","TRTEDTM":"2023-11-16 11:38:32","TRT01SDTM":"2020-11-15 17:38:32","TRT01EDTM":"2022-11-16 05:38:32","TRT02SDTM":"2022-11-16 05:38:32","TRT02EDTM":"2023-11-16 11:38:32","AP01SDTM":"2020-11-15 17:38:32","AP01EDTM":"2022-11-16 05:38:32","AP02SDTM":"2022-11-16 05:38:32","AP02EDTM":"2023-11-16 11:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-16","EOSDY":1096,"LSTALVDT":"2023-12-07","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5233,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.08721,"AVALU":"U/L","BASE2":16.08721,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-08 17:38:32","ADY":85,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-257","SUBJID":"id-257","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.83771,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-15","TRTSDTM":"2020-11-15 17:38:32","TRTEDTM":"2023-11-16 11:38:32","TRT01SDTM":"2020-11-15 17:38:32","TRT01EDTM":"2022-11-16 05:38:32","TRT02SDTM":"2022-11-16 05:38:32","TRT02EDTM":"2023-11-16 11:38:32","AP01SDTM":"2020-11-15 17:38:32","AP01EDTM":"2022-11-16 05:38:32","AP02SDTM":"2022-11-16 05:38:32","AP02EDTM":"2023-11-16 11:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-16","EOSDY":1096,"LSTALVDT":"2023-12-07","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2366,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.97031,"AVALU":"U/L","BASE2":16.08721,"BASE":12.97031,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-3.1169,"PCHG2":-19.37505,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-11 17:38:32","ADY":300,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-257","SUBJID":"id-257","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.83771,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-15","TRTSDTM":"2020-11-15 17:38:32","TRTEDTM":"2023-11-16 11:38:32","TRT01SDTM":"2020-11-15 17:38:32","TRT01EDTM":"2022-11-16 05:38:32","TRT02SDTM":"2022-11-16 05:38:32","TRT02EDTM":"2023-11-16 11:38:32","AP01SDTM":"2020-11-15 17:38:32","AP01EDTM":"2022-11-16 05:38:32","AP02SDTM":"2022-11-16 05:38:32","AP02EDTM":"2023-11-16 11:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-16","EOSDY":1096,"LSTALVDT":"2023-12-07","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":951,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.67455,"AVALU":"U/L","BASE2":16.08721,"BASE":12.97031,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.58734,"PCHG2":90.6766,"CHG":17.70424,"PCHG":136.49824,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-26 17:38:32","ADY":376,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-257","SUBJID":"id-257","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.83771,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-15","TRTSDTM":"2020-11-15 17:38:32","TRTEDTM":"2023-11-16 11:38:32","TRT01SDTM":"2020-11-15 17:38:32","TRT01EDTM":"2022-11-16 05:38:32","TRT02SDTM":"2022-11-16 05:38:32","TRT02EDTM":"2023-11-16 11:38:32","AP01SDTM":"2020-11-15 17:38:32","AP01EDTM":"2022-11-16 05:38:32","AP02SDTM":"2022-11-16 05:38:32","AP02EDTM":"2023-11-16 11:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-16","EOSDY":1096,"LSTALVDT":"2023-12-07","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4093,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.85284,"AVALU":"U/L","BASE2":16.08721,"BASE":12.97031,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.76563,"PCHG2":66.92043,"CHG":13.88253,"PCHG":107.03321,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-04 17:38:32","ADY":627,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-257","SUBJID":"id-257","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.83771,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-15","TRTSDTM":"2020-11-15 17:38:32","TRTEDTM":"2023-11-16 11:38:32","TRT01SDTM":"2020-11-15 17:38:32","TRT01EDTM":"2022-11-16 05:38:32","TRT02SDTM":"2022-11-16 05:38:32","TRT02EDTM":"2023-11-16 11:38:32","AP01SDTM":"2020-11-15 17:38:32","AP01EDTM":"2022-11-16 05:38:32","AP02SDTM":"2022-11-16 05:38:32","AP02EDTM":"2023-11-16 11:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-16","EOSDY":1096,"LSTALVDT":"2023-12-07","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5938,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.94382,"AVALU":"U/L","BASE2":16.08721,"BASE":12.97031,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.14339,"PCHG2":-75.48477,"CHG":-9.02649,"PCHG":-69.5935,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2023-01-19 17:38:32","ADY":795,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-257","SUBJID":"id-257","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.83771,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-15","TRTSDTM":"2020-11-15 17:38:32","TRTEDTM":"2023-11-16 11:38:32","TRT01SDTM":"2020-11-15 17:38:32","TRT01EDTM":"2022-11-16 05:38:32","TRT02SDTM":"2022-11-16 05:38:32","TRT02EDTM":"2023-11-16 11:38:32","AP01SDTM":"2020-11-15 17:38:32","AP01EDTM":"2022-11-16 05:38:32","AP02SDTM":"2022-11-16 05:38:32","AP02EDTM":"2023-11-16 11:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-16","EOSDY":1096,"LSTALVDT":"2023-12-07","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1672,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.41294,"AVALU":"U/L","BASE2":16.08721,"BASE":12.97031,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.67427,"PCHG2":-16.62361,"CHG":0.44263,"PCHG":3.41264,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-17 17:38:32","ADY":852,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-257","SUBJID":"id-257","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.83771,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-15","TRTSDTM":"2020-11-15 17:38:32","TRTEDTM":"2023-11-16 11:38:32","TRT01SDTM":"2020-11-15 17:38:32","TRT01EDTM":"2022-11-16 05:38:32","TRT02SDTM":"2022-11-16 05:38:32","TRT02EDTM":"2023-11-16 11:38:32","AP01SDTM":"2020-11-15 17:38:32","AP01EDTM":"2022-11-16 05:38:32","AP02SDTM":"2022-11-16 05:38:32","AP02EDTM":"2023-11-16 11:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-16","EOSDY":1096,"LSTALVDT":"2023-12-07","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3396,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.92017,"AVALU":"U/L","BASE2":16.08721,"BASE":12.97031,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.83296,"PCHG2":23.82612,"CHG":6.94986,"PCHG":53.58287,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-10-09 17:38:32","ADY":1058,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-257","SUBJID":"id-257","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.83771,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-15","TRTSDTM":"2020-11-15 17:38:32","TRTEDTM":"2023-11-16 11:38:32","TRT01SDTM":"2020-11-15 17:38:32","TRT01EDTM":"2022-11-16 05:38:32","TRT02SDTM":"2022-11-16 05:38:32","TRT02EDTM":"2023-11-16 11:38:32","AP01SDTM":"2020-11-15 17:38:32","AP01EDTM":"2022-11-16 05:38:32","AP02SDTM":"2022-11-16 05:38:32","AP02EDTM":"2023-11-16 11:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-16","EOSDY":1096,"LSTALVDT":"2023-12-07","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5326,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.98758,"AVALU":"mg/L","BASE2":7.98758,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"-2","BTOXGR":"2","ADTM":"2021-02-08 17:38:32","ADY":85,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-257","SUBJID":"id-257","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.83771,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-15","TRTSDTM":"2020-11-15 17:38:32","TRTEDTM":"2023-11-16 11:38:32","TRT01SDTM":"2020-11-15 17:38:32","TRT01EDTM":"2022-11-16 05:38:32","TRT02SDTM":"2022-11-16 05:38:32","TRT02EDTM":"2023-11-16 11:38:32","AP01SDTM":"2020-11-15 17:38:32","AP01EDTM":"2022-11-16 05:38:32","AP02SDTM":"2022-11-16 05:38:32","AP02EDTM":"2023-11-16 11:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-16","EOSDY":1096,"LSTALVDT":"2023-12-07","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3194,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.31978,"AVALU":"mg/L","BASE2":7.98758,"BASE":10.31978,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.3322,"PCHG2":29.1978,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2021-09-11 17:38:32","ADY":300,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-257","SUBJID":"id-257","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.83771,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-15","TRTSDTM":"2020-11-15 17:38:32","TRTEDTM":"2023-11-16 11:38:32","TRT01SDTM":"2020-11-15 17:38:32","TRT01EDTM":"2022-11-16 05:38:32","TRT02SDTM":"2022-11-16 05:38:32","TRT02EDTM":"2023-11-16 11:38:32","AP01SDTM":"2020-11-15 17:38:32","AP01EDTM":"2022-11-16 05:38:32","AP02SDTM":"2022-11-16 05:38:32","AP02EDTM":"2023-11-16 11:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-16","EOSDY":1096,"LSTALVDT":"2023-12-07","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5269,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.5897,"AVALU":"mg/L","BASE2":7.98758,"BASE":10.31978,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.60212,"PCHG2":20.05762,"CHG":-0.73008,"PCHG":-7.07456,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-11-26 17:38:32","ADY":376,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-257","SUBJID":"id-257","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.83771,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-15","TRTSDTM":"2020-11-15 17:38:32","TRTEDTM":"2023-11-16 11:38:32","TRT01SDTM":"2020-11-15 17:38:32","TRT01EDTM":"2022-11-16 05:38:32","TRT02SDTM":"2022-11-16 05:38:32","TRT02EDTM":"2023-11-16 11:38:32","AP01SDTM":"2020-11-15 17:38:32","AP01EDTM":"2022-11-16 05:38:32","AP02SDTM":"2022-11-16 05:38:32","AP02EDTM":"2023-11-16 11:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-16","EOSDY":1096,"LSTALVDT":"2023-12-07","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7746,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.04599,"AVALU":"mg/L","BASE2":7.98758,"BASE":10.31978,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05841,"PCHG2":0.73126,"CHG":-2.27379,"PCHG":-22.0333,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-08-04 17:38:32","ADY":627,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-257","SUBJID":"id-257","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.83771,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-15","TRTSDTM":"2020-11-15 17:38:32","TRTEDTM":"2023-11-16 11:38:32","TRT01SDTM":"2020-11-15 17:38:32","TRT01EDTM":"2022-11-16 05:38:32","TRT02SDTM":"2022-11-16 05:38:32","TRT02EDTM":"2023-11-16 11:38:32","AP01SDTM":"2020-11-15 17:38:32","AP01EDTM":"2022-11-16 05:38:32","AP02SDTM":"2022-11-16 05:38:32","AP02EDTM":"2023-11-16 11:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-16","EOSDY":1096,"LSTALVDT":"2023-12-07","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5504,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.70266,"AVALU":"mg/L","BASE2":7.98758,"BASE":10.31978,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.71508,"PCHG2":21.47183,"CHG":-0.61712,"PCHG":-5.97995,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2023-01-19 17:38:32","ADY":795,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-257","SUBJID":"id-257","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.83771,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-15","TRTSDTM":"2020-11-15 17:38:32","TRTEDTM":"2023-11-16 11:38:32","TRT01SDTM":"2020-11-15 17:38:32","TRT01EDTM":"2022-11-16 05:38:32","TRT02SDTM":"2022-11-16 05:38:32","TRT02EDTM":"2023-11-16 11:38:32","AP01SDTM":"2020-11-15 17:38:32","AP01EDTM":"2022-11-16 05:38:32","AP02SDTM":"2022-11-16 05:38:32","AP02EDTM":"2023-11-16 11:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-16","EOSDY":1096,"LSTALVDT":"2023-12-07","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8112,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.02634,"AVALU":"mg/L","BASE2":7.98758,"BASE":10.31978,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.03876,"PCHG2":25.5241,"CHG":-0.29344,"PCHG":-2.84347,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"4","BTOXGR":"2","ADTM":"2023-03-17 17:38:32","ADY":852,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-257","SUBJID":"id-257","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.83771,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-15","TRTSDTM":"2020-11-15 17:38:32","TRTEDTM":"2023-11-16 11:38:32","TRT01SDTM":"2020-11-15 17:38:32","TRT01EDTM":"2022-11-16 05:38:32","TRT02SDTM":"2022-11-16 05:38:32","TRT02EDTM":"2023-11-16 11:38:32","AP01SDTM":"2020-11-15 17:38:32","AP01EDTM":"2022-11-16 05:38:32","AP02SDTM":"2022-11-16 05:38:32","AP02EDTM":"2023-11-16 11:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-16","EOSDY":1096,"LSTALVDT":"2023-12-07","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6821,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.72187,"AVALU":"mg/L","BASE2":7.98758,"BASE":10.31978,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.73428,"PCHG2":9.19282,"CHG":-1.59791,"PCHG":-15.48399,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2023-10-09 17:38:32","ADY":1058,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-257","SUBJID":"id-257","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.83771,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-15","TRTSDTM":"2020-11-15 17:38:32","TRTEDTM":"2023-11-16 11:38:32","TRT01SDTM":"2020-11-15 17:38:32","TRT01EDTM":"2022-11-16 05:38:32","TRT02SDTM":"2022-11-16 05:38:32","TRT02EDTM":"2023-11-16 11:38:32","AP01SDTM":"2020-11-15 17:38:32","AP01EDTM":"2022-11-16 05:38:32","AP02SDTM":"2022-11-16 05:38:32","AP02EDTM":"2023-11-16 11:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-16","EOSDY":1096,"LSTALVDT":"2023-12-07","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1266,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0553,"AVALU":"g/L","BASE2":3.0553,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-02-08 17:38:32","ADY":85,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-257","SUBJID":"id-257","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.83771,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-15","TRTSDTM":"2020-11-15 17:38:32","TRTEDTM":"2023-11-16 11:38:32","TRT01SDTM":"2020-11-15 17:38:32","TRT01EDTM":"2022-11-16 05:38:32","TRT02SDTM":"2022-11-16 05:38:32","TRT02EDTM":"2023-11-16 11:38:32","AP01SDTM":"2020-11-15 17:38:32","AP01EDTM":"2022-11-16 05:38:32","AP02SDTM":"2022-11-16 05:38:32","AP02EDTM":"2023-11-16 11:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-16","EOSDY":1096,"LSTALVDT":"2023-12-07","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1242,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89331,"AVALU":"g/L","BASE2":3.0553,"BASE":2.89331,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.16199,"PCHG2":-5.30188,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-11 17:38:32","ADY":300,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-257","SUBJID":"id-257","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.83771,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-15","TRTSDTM":"2020-11-15 17:38:32","TRTEDTM":"2023-11-16 11:38:32","TRT01SDTM":"2020-11-15 17:38:32","TRT01EDTM":"2022-11-16 05:38:32","TRT02SDTM":"2022-11-16 05:38:32","TRT02EDTM":"2023-11-16 11:38:32","AP01SDTM":"2020-11-15 17:38:32","AP01EDTM":"2022-11-16 05:38:32","AP02SDTM":"2022-11-16 05:38:32","AP02EDTM":"2023-11-16 11:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-16","EOSDY":1096,"LSTALVDT":"2023-12-07","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":935,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05427,"AVALU":"g/L","BASE2":3.0553,"BASE":2.89331,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00104,"PCHG2":-0.03392,"CHG":0.16095,"PCHG":5.5629,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-11-26 17:38:32","ADY":376,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-257","SUBJID":"id-257","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.83771,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-15","TRTSDTM":"2020-11-15 17:38:32","TRTEDTM":"2023-11-16 11:38:32","TRT01SDTM":"2020-11-15 17:38:32","TRT01EDTM":"2022-11-16 05:38:32","TRT02SDTM":"2022-11-16 05:38:32","TRT02EDTM":"2023-11-16 11:38:32","AP01SDTM":"2020-11-15 17:38:32","AP01EDTM":"2022-11-16 05:38:32","AP02SDTM":"2022-11-16 05:38:32","AP02EDTM":"2023-11-16 11:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-16","EOSDY":1096,"LSTALVDT":"2023-12-07","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4805,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90653,"AVALU":"g/L","BASE2":3.0553,"BASE":2.89331,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14877,"PCHG2":-4.86914,"CHG":0.01322,"PCHG":0.45697,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-04 17:38:32","ADY":627,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-257","SUBJID":"id-257","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.83771,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-15","TRTSDTM":"2020-11-15 17:38:32","TRTEDTM":"2023-11-16 11:38:32","TRT01SDTM":"2020-11-15 17:38:32","TRT01EDTM":"2022-11-16 05:38:32","TRT02SDTM":"2022-11-16 05:38:32","TRT02EDTM":"2023-11-16 11:38:32","AP01SDTM":"2020-11-15 17:38:32","AP01EDTM":"2022-11-16 05:38:32","AP02SDTM":"2022-11-16 05:38:32","AP02EDTM":"2023-11-16 11:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-16","EOSDY":1096,"LSTALVDT":"2023-12-07","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7750,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79328,"AVALU":"g/L","BASE2":3.0553,"BASE":2.89331,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.26202,"PCHG2":-8.57596,"CHG":-0.10003,"PCHG":-3.45738,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-19 17:38:32","ADY":795,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-257","SUBJID":"id-257","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.83771,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-15","TRTSDTM":"2020-11-15 17:38:32","TRTEDTM":"2023-11-16 11:38:32","TRT01SDTM":"2020-11-15 17:38:32","TRT01EDTM":"2022-11-16 05:38:32","TRT02SDTM":"2022-11-16 05:38:32","TRT02EDTM":"2023-11-16 11:38:32","AP01SDTM":"2020-11-15 17:38:32","AP01EDTM":"2022-11-16 05:38:32","AP02SDTM":"2022-11-16 05:38:32","AP02EDTM":"2023-11-16 11:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-16","EOSDY":1096,"LSTALVDT":"2023-12-07","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2389,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99521,"AVALU":"g/L","BASE2":3.0553,"BASE":2.89331,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06009,"PCHG2":-1.96691,"CHG":0.10189,"PCHG":3.52169,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-17 17:38:32","ADY":852,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-257","SUBJID":"id-257","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.83771,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-11-15","TRTSDTM":"2020-11-15 17:38:32","TRTEDTM":"2023-11-16 11:38:32","TRT01SDTM":"2020-11-15 17:38:32","TRT01EDTM":"2022-11-16 05:38:32","TRT02SDTM":"2022-11-16 05:38:32","TRT02EDTM":"2023-11-16 11:38:32","AP01SDTM":"2020-11-15 17:38:32","AP01EDTM":"2022-11-16 05:38:32","AP02SDTM":"2022-11-16 05:38:32","AP02EDTM":"2023-11-16 11:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-16","EOSDY":1096,"LSTALVDT":"2023-12-07","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5536,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89162,"AVALU":"g/L","BASE2":3.0553,"BASE":2.89331,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16368,"PCHG2":-5.35727,"CHG":-0.00169,"PCHG":-0.05849,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-10-09 17:38:32","ADY":1058,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-263","SUBJID":"id-263","SITEID":"CHN-11","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.82823,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-03 21:51:08","TRTEDTM":"2022-04-03 15:51:08","TRT01SDTM":"2019-04-03 21:51:08","TRT01EDTM":"2021-04-03 09:51:08","TRT02SDTM":"2021-04-03 09:51:08","TRT02EDTM":"2022-04-03 15:51:08","AP01SDTM":"2019-04-03 21:51:08","AP01EDTM":"2021-04-03 09:51:08","AP02SDTM":"2021-04-03 09:51:08","AP02EDTM":"2022-04-03 15:51:08","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-03","EOSDY":1096,"LSTALVDT":"2022-05-01","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1838,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.82136,"AVALU":"U/L","BASE2":25.82136,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-06 21:51:08","ADY":156,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-263","SUBJID":"id-263","SITEID":"CHN-11","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.82823,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-03 21:51:08","TRTEDTM":"2022-04-03 15:51:08","TRT01SDTM":"2019-04-03 21:51:08","TRT01EDTM":"2021-04-03 09:51:08","TRT02SDTM":"2021-04-03 09:51:08","TRT02EDTM":"2022-04-03 15:51:08","AP01SDTM":"2019-04-03 21:51:08","AP01EDTM":"2021-04-03 09:51:08","AP02SDTM":"2021-04-03 09:51:08","AP02EDTM":"2022-04-03 15:51:08","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-03","EOSDY":1096,"LSTALVDT":"2022-05-01","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5176,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":35.57233,"AVALU":"U/L","BASE2":25.82136,"BASE":35.57233,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":9.75097,"PCHG2":37.76318,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-03 21:51:08","ADY":214,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-263","SUBJID":"id-263","SITEID":"CHN-11","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.82823,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-03 21:51:08","TRTEDTM":"2022-04-03 15:51:08","TRT01SDTM":"2019-04-03 21:51:08","TRT01EDTM":"2021-04-03 09:51:08","TRT02SDTM":"2021-04-03 09:51:08","TRT02EDTM":"2022-04-03 15:51:08","AP01SDTM":"2019-04-03 21:51:08","AP01EDTM":"2021-04-03 09:51:08","AP02SDTM":"2021-04-03 09:51:08","AP02EDTM":"2022-04-03 15:51:08","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-03","EOSDY":1096,"LSTALVDT":"2022-05-01","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6350,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.7176,"AVALU":"U/L","BASE2":25.82136,"BASE":35.57233,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.10376,"PCHG2":-12.02012,"CHG":-12.85473,"PCHG":-36.13687,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-19 21:51:08","ADY":351,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-263","SUBJID":"id-263","SITEID":"CHN-11","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.82823,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-03 21:51:08","TRTEDTM":"2022-04-03 15:51:08","TRT01SDTM":"2019-04-03 21:51:08","TRT01EDTM":"2021-04-03 09:51:08","TRT02SDTM":"2021-04-03 09:51:08","TRT02EDTM":"2022-04-03 15:51:08","AP01SDTM":"2019-04-03 21:51:08","AP01EDTM":"2021-04-03 09:51:08","AP02SDTM":"2021-04-03 09:51:08","AP02EDTM":"2022-04-03 15:51:08","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-03","EOSDY":1096,"LSTALVDT":"2022-05-01","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":968,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.89986,"AVALU":"U/L","BASE2":25.82136,"BASE":35.57233,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.9215,"PCHG2":-34.55085,"CHG":-18.67247,"PCHG":-52.49155,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-14 21:51:08","ADY":652,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-263","SUBJID":"id-263","SITEID":"CHN-11","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.82823,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-03 21:51:08","TRTEDTM":"2022-04-03 15:51:08","TRT01SDTM":"2019-04-03 21:51:08","TRT01EDTM":"2021-04-03 09:51:08","TRT02SDTM":"2021-04-03 09:51:08","TRT02EDTM":"2022-04-03 15:51:08","AP01SDTM":"2019-04-03 21:51:08","AP01EDTM":"2021-04-03 09:51:08","AP02SDTM":"2021-04-03 09:51:08","AP02EDTM":"2022-04-03 15:51:08","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-03","EOSDY":1096,"LSTALVDT":"2022-05-01","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":687,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.77648,"AVALU":"U/L","BASE2":25.82136,"BASE":35.57233,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.04489,"PCHG2":-4.04659,"CHG":-10.79585,"PCHG":-30.34902,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-29 21:51:08","ADY":787,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-263","SUBJID":"id-263","SITEID":"CHN-11","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.82823,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-03 21:51:08","TRTEDTM":"2022-04-03 15:51:08","TRT01SDTM":"2019-04-03 21:51:08","TRT01EDTM":"2021-04-03 09:51:08","TRT02SDTM":"2021-04-03 09:51:08","TRT02EDTM":"2022-04-03 15:51:08","AP01SDTM":"2019-04-03 21:51:08","AP01EDTM":"2021-04-03 09:51:08","AP02SDTM":"2021-04-03 09:51:08","AP02EDTM":"2022-04-03 15:51:08","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-03","EOSDY":1096,"LSTALVDT":"2022-05-01","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4022,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.93177,"AVALU":"U/L","BASE2":25.82136,"BASE":35.57233,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.11041,"PCHG2":8.17311,"CHG":-7.64056,"PCHG":-21.47894,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-03 21:51:08","ADY":884,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-263","SUBJID":"id-263","SITEID":"CHN-11","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.82823,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-03 21:51:08","TRTEDTM":"2022-04-03 15:51:08","TRT01SDTM":"2019-04-03 21:51:08","TRT01EDTM":"2021-04-03 09:51:08","TRT02SDTM":"2021-04-03 09:51:08","TRT02EDTM":"2022-04-03 15:51:08","AP01SDTM":"2019-04-03 21:51:08","AP01EDTM":"2021-04-03 09:51:08","AP02SDTM":"2021-04-03 09:51:08","AP02EDTM":"2022-04-03 15:51:08","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-03","EOSDY":1096,"LSTALVDT":"2022-05-01","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3360,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.7709,"AVALU":"U/L","BASE2":25.82136,"BASE":35.57233,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.05046,"PCHG2":-46.66857,"CHG":-21.80143,"PCHG":-61.2876,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-06 21:51:08","ADY":1068,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-263","SUBJID":"id-263","SITEID":"CHN-11","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.82823,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-03 21:51:08","TRTEDTM":"2022-04-03 15:51:08","TRT01SDTM":"2019-04-03 21:51:08","TRT01EDTM":"2021-04-03 09:51:08","TRT02SDTM":"2021-04-03 09:51:08","TRT02EDTM":"2022-04-03 15:51:08","AP01SDTM":"2019-04-03 21:51:08","AP01EDTM":"2021-04-03 09:51:08","AP02SDTM":"2021-04-03 09:51:08","AP02EDTM":"2022-04-03 15:51:08","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-03","EOSDY":1096,"LSTALVDT":"2022-05-01","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8073,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.52737,"AVALU":"mg/L","BASE2":9.52737,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-3","ADTM":"2019-09-06 21:51:08","ADY":156,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-263","SUBJID":"id-263","SITEID":"CHN-11","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.82823,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-03 21:51:08","TRTEDTM":"2022-04-03 15:51:08","TRT01SDTM":"2019-04-03 21:51:08","TRT01EDTM":"2021-04-03 09:51:08","TRT02SDTM":"2021-04-03 09:51:08","TRT02EDTM":"2022-04-03 15:51:08","AP01SDTM":"2019-04-03 21:51:08","AP01EDTM":"2021-04-03 09:51:08","AP02SDTM":"2021-04-03 09:51:08","AP02EDTM":"2022-04-03 15:51:08","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-03","EOSDY":1096,"LSTALVDT":"2022-05-01","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2076,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.72995,"AVALU":"mg/L","BASE2":9.52737,"BASE":7.72995,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.79743,"PCHG2":-18.86593,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2019-11-03 21:51:08","ADY":214,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-263","SUBJID":"id-263","SITEID":"CHN-11","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.82823,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-03 21:51:08","TRTEDTM":"2022-04-03 15:51:08","TRT01SDTM":"2019-04-03 21:51:08","TRT01EDTM":"2021-04-03 09:51:08","TRT02SDTM":"2021-04-03 09:51:08","TRT02EDTM":"2022-04-03 15:51:08","AP01SDTM":"2019-04-03 21:51:08","AP01EDTM":"2021-04-03 09:51:08","AP02SDTM":"2021-04-03 09:51:08","AP02EDTM":"2022-04-03 15:51:08","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-03","EOSDY":1096,"LSTALVDT":"2022-05-01","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4271,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.26961,"AVALU":"mg/L","BASE2":9.52737,"BASE":7.72995,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.25776,"PCHG2":-23.69764,"CHG":-0.46034,"PCHG":-5.95522,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-2","BTOXGR":"-3","ADTM":"2020-03-19 21:51:08","ADY":351,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-263","SUBJID":"id-263","SITEID":"CHN-11","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.82823,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-03 21:51:08","TRTEDTM":"2022-04-03 15:51:08","TRT01SDTM":"2019-04-03 21:51:08","TRT01EDTM":"2021-04-03 09:51:08","TRT02SDTM":"2021-04-03 09:51:08","TRT02EDTM":"2022-04-03 15:51:08","AP01SDTM":"2019-04-03 21:51:08","AP01EDTM":"2021-04-03 09:51:08","AP02SDTM":"2021-04-03 09:51:08","AP02EDTM":"2022-04-03 15:51:08","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-03","EOSDY":1096,"LSTALVDT":"2022-05-01","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1884,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.6423,"AVALU":"mg/L","BASE2":9.52737,"BASE":7.72995,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.88507,"PCHG2":-9.2898,"CHG":0.91235,"PCHG":11.80284,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-01-14 21:51:08","ADY":652,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-263","SUBJID":"id-263","SITEID":"CHN-11","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.82823,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-03 21:51:08","TRTEDTM":"2022-04-03 15:51:08","TRT01SDTM":"2019-04-03 21:51:08","TRT01EDTM":"2021-04-03 09:51:08","TRT02SDTM":"2021-04-03 09:51:08","TRT02EDTM":"2022-04-03 15:51:08","AP01SDTM":"2019-04-03 21:51:08","AP01EDTM":"2021-04-03 09:51:08","AP02SDTM":"2021-04-03 09:51:08","AP02EDTM":"2022-04-03 15:51:08","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-03","EOSDY":1096,"LSTALVDT":"2022-05-01","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7791,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.83441,"AVALU":"mg/L","BASE2":9.52737,"BASE":7.72995,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.69296,"PCHG2":-7.27338,"CHG":1.10447,"PCHG":14.28814,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-05-29 21:51:08","ADY":787,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-263","SUBJID":"id-263","SITEID":"CHN-11","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.82823,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-03 21:51:08","TRTEDTM":"2022-04-03 15:51:08","TRT01SDTM":"2019-04-03 21:51:08","TRT01EDTM":"2021-04-03 09:51:08","TRT02SDTM":"2021-04-03 09:51:08","TRT02EDTM":"2022-04-03 15:51:08","AP01SDTM":"2019-04-03 21:51:08","AP01EDTM":"2021-04-03 09:51:08","AP02SDTM":"2021-04-03 09:51:08","AP02EDTM":"2022-04-03 15:51:08","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-03","EOSDY":1096,"LSTALVDT":"2022-05-01","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":503,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.40783,"AVALU":"mg/L","BASE2":9.52737,"BASE":7.72995,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11955,"PCHG2":-1.25476,"CHG":1.67788,"PCHG":21.70626,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-09-03 21:51:08","ADY":884,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-263","SUBJID":"id-263","SITEID":"CHN-11","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.82823,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-03 21:51:08","TRTEDTM":"2022-04-03 15:51:08","TRT01SDTM":"2019-04-03 21:51:08","TRT01EDTM":"2021-04-03 09:51:08","TRT02SDTM":"2021-04-03 09:51:08","TRT02EDTM":"2022-04-03 15:51:08","AP01SDTM":"2019-04-03 21:51:08","AP01EDTM":"2021-04-03 09:51:08","AP02SDTM":"2021-04-03 09:51:08","AP02EDTM":"2022-04-03 15:51:08","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-03","EOSDY":1096,"LSTALVDT":"2022-05-01","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1523,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.96936,"AVALU":"mg/L","BASE2":9.52737,"BASE":7.72995,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.55801,"PCHG2":-16.35301,"CHG":0.23942,"PCHG":3.09724,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2022-03-06 21:51:08","ADY":1068,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-263","SUBJID":"id-263","SITEID":"CHN-11","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.82823,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-03 21:51:08","TRTEDTM":"2022-04-03 15:51:08","TRT01SDTM":"2019-04-03 21:51:08","TRT01EDTM":"2021-04-03 09:51:08","TRT02SDTM":"2021-04-03 09:51:08","TRT02EDTM":"2022-04-03 15:51:08","AP01SDTM":"2019-04-03 21:51:08","AP01EDTM":"2021-04-03 09:51:08","AP02SDTM":"2021-04-03 09:51:08","AP02EDTM":"2022-04-03 15:51:08","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-03","EOSDY":1096,"LSTALVDT":"2022-05-01","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3341,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99441,"AVALU":"g/L","BASE2":2.99441,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-06 21:51:08","ADY":156,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-263","SUBJID":"id-263","SITEID":"CHN-11","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.82823,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-03 21:51:08","TRTEDTM":"2022-04-03 15:51:08","TRT01SDTM":"2019-04-03 21:51:08","TRT01EDTM":"2021-04-03 09:51:08","TRT02SDTM":"2021-04-03 09:51:08","TRT02EDTM":"2022-04-03 15:51:08","AP01SDTM":"2019-04-03 21:51:08","AP01EDTM":"2021-04-03 09:51:08","AP02SDTM":"2021-04-03 09:51:08","AP02EDTM":"2022-04-03 15:51:08","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-03","EOSDY":1096,"LSTALVDT":"2022-05-01","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6256,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77858,"AVALU":"g/L","BASE2":2.99441,"BASE":2.77858,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.21583,"PCHG2":-7.20761,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-03 21:51:08","ADY":214,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-263","SUBJID":"id-263","SITEID":"CHN-11","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.82823,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-03 21:51:08","TRTEDTM":"2022-04-03 15:51:08","TRT01SDTM":"2019-04-03 21:51:08","TRT01EDTM":"2021-04-03 09:51:08","TRT02SDTM":"2021-04-03 09:51:08","TRT02EDTM":"2022-04-03 15:51:08","AP01SDTM":"2019-04-03 21:51:08","AP01EDTM":"2021-04-03 09:51:08","AP02SDTM":"2021-04-03 09:51:08","AP02EDTM":"2022-04-03 15:51:08","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-03","EOSDY":1096,"LSTALVDT":"2022-05-01","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6342,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97894,"AVALU":"g/L","BASE2":2.99441,"BASE":2.77858,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01547,"PCHG2":-0.51661,"CHG":0.20036,"PCHG":7.21071,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-19 21:51:08","ADY":351,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-263","SUBJID":"id-263","SITEID":"CHN-11","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.82823,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-03 21:51:08","TRTEDTM":"2022-04-03 15:51:08","TRT01SDTM":"2019-04-03 21:51:08","TRT01EDTM":"2021-04-03 09:51:08","TRT02SDTM":"2021-04-03 09:51:08","TRT02EDTM":"2022-04-03 15:51:08","AP01SDTM":"2019-04-03 21:51:08","AP01EDTM":"2021-04-03 09:51:08","AP02SDTM":"2021-04-03 09:51:08","AP02EDTM":"2022-04-03 15:51:08","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-03","EOSDY":1096,"LSTALVDT":"2022-05-01","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6233,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94446,"AVALU":"g/L","BASE2":2.99441,"BASE":2.77858,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04995,"PCHG2":-1.66811,"CHG":0.16588,"PCHG":5.96978,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-14 21:51:08","ADY":652,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-263","SUBJID":"id-263","SITEID":"CHN-11","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.82823,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-03 21:51:08","TRTEDTM":"2022-04-03 15:51:08","TRT01SDTM":"2019-04-03 21:51:08","TRT01EDTM":"2021-04-03 09:51:08","TRT02SDTM":"2021-04-03 09:51:08","TRT02EDTM":"2022-04-03 15:51:08","AP01SDTM":"2019-04-03 21:51:08","AP01EDTM":"2021-04-03 09:51:08","AP02SDTM":"2021-04-03 09:51:08","AP02EDTM":"2022-04-03 15:51:08","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-03","EOSDY":1096,"LSTALVDT":"2022-05-01","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7912,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91226,"AVALU":"g/L","BASE2":2.99441,"BASE":2.77858,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08215,"PCHG2":-2.74328,"CHG":0.13368,"PCHG":4.81109,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-29 21:51:08","ADY":787,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-263","SUBJID":"id-263","SITEID":"CHN-11","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.82823,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-03 21:51:08","TRTEDTM":"2022-04-03 15:51:08","TRT01SDTM":"2019-04-03 21:51:08","TRT01EDTM":"2021-04-03 09:51:08","TRT02SDTM":"2021-04-03 09:51:08","TRT02EDTM":"2022-04-03 15:51:08","AP01SDTM":"2019-04-03 21:51:08","AP01EDTM":"2021-04-03 09:51:08","AP02SDTM":"2021-04-03 09:51:08","AP02EDTM":"2022-04-03 15:51:08","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-03","EOSDY":1096,"LSTALVDT":"2022-05-01","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":308,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99474,"AVALU":"g/L","BASE2":2.99441,"BASE":2.77858,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00033,"PCHG2":0.01101,"CHG":0.21615,"PCHG":7.77932,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-03 21:51:08","ADY":884,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-263","SUBJID":"id-263","SITEID":"CHN-11","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.82823,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-03 21:51:08","TRTEDTM":"2022-04-03 15:51:08","TRT01SDTM":"2019-04-03 21:51:08","TRT01EDTM":"2021-04-03 09:51:08","TRT02SDTM":"2021-04-03 09:51:08","TRT02EDTM":"2022-04-03 15:51:08","AP01SDTM":"2019-04-03 21:51:08","AP01EDTM":"2021-04-03 09:51:08","AP02SDTM":"2021-04-03 09:51:08","AP02EDTM":"2022-04-03 15:51:08","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-03","EOSDY":1096,"LSTALVDT":"2022-05-01","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4233,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95883,"AVALU":"g/L","BASE2":2.99441,"BASE":2.77858,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03558,"PCHG2":-1.18819,"CHG":0.18025,"PCHG":6.48697,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-06 21:51:08","ADY":1068,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-27","SUBJID":"id-27","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.81348,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-14","TRTSDTM":"2019-11-18 05:24:03","TRT01SDTM":"2019-11-18 05:24:03","AP01SDTM":"2019-11-18 05:24:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7135,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.76583,"AVALU":"U/L","BASE2":29.76583,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-25 05:24:03","ADY":99,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-27","SUBJID":"id-27","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.81348,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-14","TRTSDTM":"2019-11-18 05:24:03","TRT01SDTM":"2019-11-18 05:24:03","AP01SDTM":"2019-11-18 05:24:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6072,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.98771,"AVALU":"U/L","BASE2":29.76583,"BASE":14.98771,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-14.77812,"PCHG2":-49.64794,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-24 05:24:03","ADY":464,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-27","SUBJID":"id-27","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.81348,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-14","TRTSDTM":"2019-11-18 05:24:03","TRT01SDTM":"2019-11-18 05:24:03","AP01SDTM":"2019-11-18 05:24:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5242,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.46931,"AVALU":"U/L","BASE2":29.76583,"BASE":14.98771,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.29652,"PCHG2":-4.35574,"CHG":13.4816,"PCHG":89.95104,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-25 05:24:03","ADY":646,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-27","SUBJID":"id-27","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.81348,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-14","TRTSDTM":"2019-11-18 05:24:03","TRT01SDTM":"2019-11-18 05:24:03","AP01SDTM":"2019-11-18 05:24:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3701,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.83549,"AVALU":"U/L","BASE2":29.76583,"BASE":14.98771,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.93034,"PCHG2":-60.238,"CHG":-3.15222,"PCHG":-21.03202,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-04 05:24:03","ADY":656,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-27","SUBJID":"id-27","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.81348,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-14","TRTSDTM":"2019-11-18 05:24:03","TRT01SDTM":"2019-11-18 05:24:03","AP01SDTM":"2019-11-18 05:24:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2470,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.27111,"AVALU":"U/L","BASE2":29.76583,"BASE":14.98771,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-19.49472,"PCHG2":-65.49361,"CHG":-4.71659,"PCHG":-31.46975,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-26 05:24:03","ADY":678,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-27","SUBJID":"id-27","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.81348,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-14","TRTSDTM":"2019-11-18 05:24:03","TRT01SDTM":"2019-11-18 05:24:03","AP01SDTM":"2019-11-18 05:24:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":890,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.247,"AVALU":"U/L","BASE2":29.76583,"BASE":14.98771,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.51884,"PCHG2":-5.10262,"CHG":13.25929,"PCHG":88.46774,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-20 05:24:03","ADY":702,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-27","SUBJID":"id-27","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.81348,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-14","TRTSDTM":"2019-11-18 05:24:03","TRT01SDTM":"2019-11-18 05:24:03","AP01SDTM":"2019-11-18 05:24:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7544,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.40564,"AVALU":"U/L","BASE2":29.76583,"BASE":14.98771,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.63981,"PCHG2":2.14948,"CHG":15.41794,"PCHG":102.87053,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-11 05:24:03","ADY":724,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-27","SUBJID":"id-27","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.81348,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-14","TRTSDTM":"2019-11-18 05:24:03","TRT01SDTM":"2019-11-18 05:24:03","AP01SDTM":"2019-11-18 05:24:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6024,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.86755,"AVALU":"mg/L","BASE2":8.86755,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-02-25 05:24:03","ADY":99,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-27","SUBJID":"id-27","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.81348,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-14","TRTSDTM":"2019-11-18 05:24:03","TRT01SDTM":"2019-11-18 05:24:03","AP01SDTM":"2019-11-18 05:24:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":925,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.92723,"AVALU":"mg/L","BASE2":8.86755,"BASE":6.92723,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.94032,"PCHG2":-21.88109,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2021-02-24 05:24:03","ADY":464,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-27","SUBJID":"id-27","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.81348,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-14","TRTSDTM":"2019-11-18 05:24:03","TRT01SDTM":"2019-11-18 05:24:03","AP01SDTM":"2019-11-18 05:24:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7777,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.60695,"AVALU":"mg/L","BASE2":8.86755,"BASE":6.92723,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.73941,"PCHG2":8.33833,"CHG":2.67972,"PCHG":38.68388,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-08-25 05:24:03","ADY":646,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-27","SUBJID":"id-27","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.81348,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-14","TRTSDTM":"2019-11-18 05:24:03","TRT01SDTM":"2019-11-18 05:24:03","AP01SDTM":"2019-11-18 05:24:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":115,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.49506,"AVALU":"mg/L","BASE2":8.86755,"BASE":6.92723,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.37248,"PCHG2":-4.20052,"CHG":1.56783,"PCHG":22.6329,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-09-04 05:24:03","ADY":656,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-27","SUBJID":"id-27","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.81348,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-14","TRTSDTM":"2019-11-18 05:24:03","TRT01SDTM":"2019-11-18 05:24:03","AP01SDTM":"2019-11-18 05:24:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5473,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.52798,"AVALU":"mg/L","BASE2":8.86755,"BASE":6.92723,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.33957,"PCHG2":-3.82936,"CHG":1.60075,"PCHG":23.10802,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-09-26 05:24:03","ADY":678,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-27","SUBJID":"id-27","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.81348,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-14","TRTSDTM":"2019-11-18 05:24:03","TRT01SDTM":"2019-11-18 05:24:03","AP01SDTM":"2019-11-18 05:24:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1227,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.37815,"AVALU":"mg/L","BASE2":8.86755,"BASE":6.92723,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.51061,"PCHG2":5.75814,"CHG":2.45092,"PCHG":35.38097,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-10-20 05:24:03","ADY":702,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-27","SUBJID":"id-27","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.81348,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-14","TRTSDTM":"2019-11-18 05:24:03","TRT01SDTM":"2019-11-18 05:24:03","AP01SDTM":"2019-11-18 05:24:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2159,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.97386,"AVALU":"mg/L","BASE2":8.86755,"BASE":6.92723,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.89368,"PCHG2":-10.07813,"CHG":1.04663,"PCHG":15.10897,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-2","ADTM":"2021-11-11 05:24:03","ADY":724,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-27","SUBJID":"id-27","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.81348,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-14","TRTSDTM":"2019-11-18 05:24:03","TRT01SDTM":"2019-11-18 05:24:03","AP01SDTM":"2019-11-18 05:24:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4365,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.6416,"AVALU":"g/L","BASE2":2.6416,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-25 05:24:03","ADY":99,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-27","SUBJID":"id-27","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.81348,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-14","TRTSDTM":"2019-11-18 05:24:03","TRT01SDTM":"2019-11-18 05:24:03","AP01SDTM":"2019-11-18 05:24:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5790,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95733,"AVALU":"g/L","BASE2":2.6416,"BASE":2.95733,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.31573,"PCHG2":11.95207,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-24 05:24:03","ADY":464,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-27","SUBJID":"id-27","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.81348,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-14","TRTSDTM":"2019-11-18 05:24:03","TRT01SDTM":"2019-11-18 05:24:03","AP01SDTM":"2019-11-18 05:24:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3783,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79897,"AVALU":"g/L","BASE2":2.6416,"BASE":2.95733,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15737,"PCHG2":5.95731,"CHG":-0.15836,"PCHG":-5.35475,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-25 05:24:03","ADY":646,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-27","SUBJID":"id-27","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.81348,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-14","TRTSDTM":"2019-11-18 05:24:03","TRT01SDTM":"2019-11-18 05:24:03","AP01SDTM":"2019-11-18 05:24:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1283,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87168,"AVALU":"g/L","BASE2":2.6416,"BASE":2.95733,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.23008,"PCHG2":8.70996,"CHG":-0.08564,"PCHG":-2.89598,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-04 05:24:03","ADY":656,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-27","SUBJID":"id-27","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.81348,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-14","TRTSDTM":"2019-11-18 05:24:03","TRT01SDTM":"2019-11-18 05:24:03","AP01SDTM":"2019-11-18 05:24:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":352,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88962,"AVALU":"g/L","BASE2":2.6416,"BASE":2.95733,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.24801,"PCHG2":9.38879,"CHG":-0.06771,"PCHG":-2.28962,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-26 05:24:03","ADY":678,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-27","SUBJID":"id-27","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.81348,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-14","TRTSDTM":"2019-11-18 05:24:03","TRT01SDTM":"2019-11-18 05:24:03","AP01SDTM":"2019-11-18 05:24:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4479,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01859,"AVALU":"g/L","BASE2":2.6416,"BASE":2.95733,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.37698,"PCHG2":14.27106,"CHG":0.06126,"PCHG":2.07142,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-10-20 05:24:03","ADY":702,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-27","SUBJID":"id-27","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":12.81348,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-14","TRTSDTM":"2019-11-18 05:24:03","TRT01SDTM":"2019-11-18 05:24:03","AP01SDTM":"2019-11-18 05:24:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3976,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03598,"AVALU":"g/L","BASE2":2.6416,"BASE":2.95733,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.39438,"PCHG2":14.92963,"CHG":0.07866,"PCHG":2.65967,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-11-11 05:24:03","ADY":724,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-278","SUBJID":"id-278","SITEID":"CHN-11","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.07981,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-23","TRTSDTM":"2020-08-24 06:55:10","TRTEDTM":"2023-08-25 00:55:10","TRT01SDTM":"2020-08-24 06:55:10","TRT01EDTM":"2022-08-24 18:55:10","TRT02SDTM":"2022-08-24 18:55:10","TRT02EDTM":"2023-08-25 00:55:10","AP01SDTM":"2020-08-24 06:55:10","AP01EDTM":"2022-08-24 18:55:10","AP02SDTM":"2022-08-24 18:55:10","AP02EDTM":"2023-08-25 00:55:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-25","EOSDY":1096,"LSTALVDT":"2023-09-07","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2959,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":37.71337,"AVALU":"U/L","BASE2":37.71337,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-29 06:55:10","ADY":97,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-278","SUBJID":"id-278","SITEID":"CHN-11","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.07981,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-23","TRTSDTM":"2020-08-24 06:55:10","TRTEDTM":"2023-08-25 00:55:10","TRT01SDTM":"2020-08-24 06:55:10","TRT01EDTM":"2022-08-24 18:55:10","TRT02SDTM":"2022-08-24 18:55:10","TRT02EDTM":"2023-08-25 00:55:10","AP01SDTM":"2020-08-24 06:55:10","AP01EDTM":"2022-08-24 18:55:10","AP02SDTM":"2022-08-24 18:55:10","AP02EDTM":"2023-08-25 00:55:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-25","EOSDY":1096,"LSTALVDT":"2023-09-07","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3291,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.93581,"AVALU":"U/L","BASE2":37.71337,"BASE":26.93581,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-10.77756,"PCHG2":-28.57756,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-02 06:55:10","ADY":435,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-278","SUBJID":"id-278","SITEID":"CHN-11","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.07981,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-23","TRTSDTM":"2020-08-24 06:55:10","TRTEDTM":"2023-08-25 00:55:10","TRT01SDTM":"2020-08-24 06:55:10","TRT01EDTM":"2022-08-24 18:55:10","TRT02SDTM":"2022-08-24 18:55:10","TRT02EDTM":"2023-08-25 00:55:10","AP01SDTM":"2020-08-24 06:55:10","AP01EDTM":"2022-08-24 18:55:10","AP02SDTM":"2022-08-24 18:55:10","AP02EDTM":"2023-08-25 00:55:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-25","EOSDY":1096,"LSTALVDT":"2023-09-07","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1817,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.84965,"AVALU":"U/L","BASE2":37.71337,"BASE":26.93581,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.86372,"PCHG2":-39.41234,"CHG":-4.08616,"PCHG":-15.16999,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-14 06:55:10","ADY":539,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-278","SUBJID":"id-278","SITEID":"CHN-11","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.07981,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-23","TRTSDTM":"2020-08-24 06:55:10","TRTEDTM":"2023-08-25 00:55:10","TRT01SDTM":"2020-08-24 06:55:10","TRT01EDTM":"2022-08-24 18:55:10","TRT02SDTM":"2022-08-24 18:55:10","TRT02EDTM":"2023-08-25 00:55:10","AP01SDTM":"2020-08-24 06:55:10","AP01EDTM":"2022-08-24 18:55:10","AP02SDTM":"2022-08-24 18:55:10","AP02EDTM":"2023-08-25 00:55:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-25","EOSDY":1096,"LSTALVDT":"2023-09-07","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2691,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.30922,"AVALU":"U/L","BASE2":37.71337,"BASE":26.93581,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.40416,"PCHG2":-30.23903,"CHG":-0.6266,"PCHG":-2.32626,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-23 06:55:10","ADY":548,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-278","SUBJID":"id-278","SITEID":"CHN-11","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.07981,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-23","TRTSDTM":"2020-08-24 06:55:10","TRTEDTM":"2023-08-25 00:55:10","TRT01SDTM":"2020-08-24 06:55:10","TRT01EDTM":"2022-08-24 18:55:10","TRT02SDTM":"2022-08-24 18:55:10","TRT02EDTM":"2023-08-25 00:55:10","AP01SDTM":"2020-08-24 06:55:10","AP01EDTM":"2022-08-24 18:55:10","AP02SDTM":"2022-08-24 18:55:10","AP02EDTM":"2023-08-25 00:55:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-25","EOSDY":1096,"LSTALVDT":"2023-09-07","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1490,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.42324,"AVALU":"U/L","BASE2":37.71337,"BASE":26.93581,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.29014,"PCHG2":-16.6788,"CHG":4.48742,"PCHG":16.6597,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-14 06:55:10","ADY":628,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-278","SUBJID":"id-278","SITEID":"CHN-11","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.07981,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-23","TRTSDTM":"2020-08-24 06:55:10","TRTEDTM":"2023-08-25 00:55:10","TRT01SDTM":"2020-08-24 06:55:10","TRT01EDTM":"2022-08-24 18:55:10","TRT02SDTM":"2022-08-24 18:55:10","TRT02EDTM":"2023-08-25 00:55:10","AP01SDTM":"2020-08-24 06:55:10","AP01EDTM":"2022-08-24 18:55:10","AP02SDTM":"2022-08-24 18:55:10","AP02EDTM":"2023-08-25 00:55:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-25","EOSDY":1096,"LSTALVDT":"2023-09-07","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2309,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.32439,"AVALU":"U/L","BASE2":37.71337,"BASE":26.93581,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.38899,"PCHG2":-38.15354,"CHG":-3.61143,"PCHG":-13.40752,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-26 06:55:10","ADY":916,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-278","SUBJID":"id-278","SITEID":"CHN-11","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.07981,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-23","TRTSDTM":"2020-08-24 06:55:10","TRTEDTM":"2023-08-25 00:55:10","TRT01SDTM":"2020-08-24 06:55:10","TRT01EDTM":"2022-08-24 18:55:10","TRT02SDTM":"2022-08-24 18:55:10","TRT02EDTM":"2023-08-25 00:55:10","AP01SDTM":"2020-08-24 06:55:10","AP01EDTM":"2022-08-24 18:55:10","AP02SDTM":"2022-08-24 18:55:10","AP02EDTM":"2023-08-25 00:55:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-25","EOSDY":1096,"LSTALVDT":"2023-09-07","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7095,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.37533,"AVALU":"U/L","BASE2":37.71337,"BASE":26.93581,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-30.33805,"PCHG2":-80.44374,"CHG":-19.56049,"PCHG":-72.61889,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-31 06:55:10","ADY":1071,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-278","SUBJID":"id-278","SITEID":"CHN-11","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.07981,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-23","TRTSDTM":"2020-08-24 06:55:10","TRTEDTM":"2023-08-25 00:55:10","TRT01SDTM":"2020-08-24 06:55:10","TRT01EDTM":"2022-08-24 18:55:10","TRT02SDTM":"2022-08-24 18:55:10","TRT02EDTM":"2023-08-25 00:55:10","AP01SDTM":"2020-08-24 06:55:10","AP01EDTM":"2022-08-24 18:55:10","AP02SDTM":"2022-08-24 18:55:10","AP02EDTM":"2023-08-25 00:55:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-25","EOSDY":1096,"LSTALVDT":"2023-09-07","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5557,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.43153,"AVALU":"mg/L","BASE2":7.43153,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-11-29 06:55:10","ADY":97,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-278","SUBJID":"id-278","SITEID":"CHN-11","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.07981,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-23","TRTSDTM":"2020-08-24 06:55:10","TRTEDTM":"2023-08-25 00:55:10","TRT01SDTM":"2020-08-24 06:55:10","TRT01EDTM":"2022-08-24 18:55:10","TRT02SDTM":"2022-08-24 18:55:10","TRT02EDTM":"2023-08-25 00:55:10","AP01SDTM":"2020-08-24 06:55:10","AP01EDTM":"2022-08-24 18:55:10","AP02SDTM":"2022-08-24 18:55:10","AP02EDTM":"2023-08-25 00:55:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-25","EOSDY":1096,"LSTALVDT":"2023-09-07","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1012,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.86462,"AVALU":"mg/L","BASE2":7.43153,"BASE":9.86462,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.43309,"PCHG2":32.7401,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-02 06:55:10","ADY":435,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-278","SUBJID":"id-278","SITEID":"CHN-11","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.07981,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-23","TRTSDTM":"2020-08-24 06:55:10","TRTEDTM":"2023-08-25 00:55:10","TRT01SDTM":"2020-08-24 06:55:10","TRT01EDTM":"2022-08-24 18:55:10","TRT02SDTM":"2022-08-24 18:55:10","TRT02EDTM":"2023-08-25 00:55:10","AP01SDTM":"2020-08-24 06:55:10","AP01EDTM":"2022-08-24 18:55:10","AP02SDTM":"2022-08-24 18:55:10","AP02EDTM":"2023-08-25 00:55:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-25","EOSDY":1096,"LSTALVDT":"2023-09-07","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3353,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.9378,"AVALU":"mg/L","BASE2":7.43153,"BASE":9.86462,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.50627,"PCHG2":20.26857,"CHG":-0.92683,"PCHG":-9.39545,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-14 06:55:10","ADY":539,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-278","SUBJID":"id-278","SITEID":"CHN-11","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.07981,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-23","TRTSDTM":"2020-08-24 06:55:10","TRTEDTM":"2023-08-25 00:55:10","TRT01SDTM":"2020-08-24 06:55:10","TRT01EDTM":"2022-08-24 18:55:10","TRT02SDTM":"2022-08-24 18:55:10","TRT02EDTM":"2023-08-25 00:55:10","AP01SDTM":"2020-08-24 06:55:10","AP01EDTM":"2022-08-24 18:55:10","AP02SDTM":"2022-08-24 18:55:10","AP02EDTM":"2023-08-25 00:55:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-25","EOSDY":1096,"LSTALVDT":"2023-09-07","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":217,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.70971,"AVALU":"mg/L","BASE2":7.43153,"BASE":9.86462,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.27817,"PCHG2":17.19931,"CHG":-1.15492,"PCHG":-11.70768,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-23 06:55:10","ADY":548,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-278","SUBJID":"id-278","SITEID":"CHN-11","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.07981,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-23","TRTSDTM":"2020-08-24 06:55:10","TRTEDTM":"2023-08-25 00:55:10","TRT01SDTM":"2020-08-24 06:55:10","TRT01EDTM":"2022-08-24 18:55:10","TRT02SDTM":"2022-08-24 18:55:10","TRT02EDTM":"2023-08-25 00:55:10","AP01SDTM":"2020-08-24 06:55:10","AP01EDTM":"2022-08-24 18:55:10","AP02SDTM":"2022-08-24 18:55:10","AP02EDTM":"2023-08-25 00:55:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-25","EOSDY":1096,"LSTALVDT":"2023-09-07","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7581,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.12234,"AVALU":"mg/L","BASE2":7.43153,"BASE":9.86462,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.69081,"PCHG2":22.7518,"CHG":-0.74228,"PCHG":-7.52471,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-14 06:55:10","ADY":628,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-278","SUBJID":"id-278","SITEID":"CHN-11","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.07981,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-23","TRTSDTM":"2020-08-24 06:55:10","TRTEDTM":"2023-08-25 00:55:10","TRT01SDTM":"2020-08-24 06:55:10","TRT01EDTM":"2022-08-24 18:55:10","TRT02SDTM":"2022-08-24 18:55:10","TRT02EDTM":"2023-08-25 00:55:10","AP01SDTM":"2020-08-24 06:55:10","AP01EDTM":"2022-08-24 18:55:10","AP02SDTM":"2022-08-24 18:55:10","AP02EDTM":"2023-08-25 00:55:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-25","EOSDY":1096,"LSTALVDT":"2023-09-07","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7168,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.19328,"AVALU":"mg/L","BASE2":7.43153,"BASE":9.86462,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.76175,"PCHG2":23.70643,"CHG":-0.67134,"PCHG":-6.80554,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-26 06:55:10","ADY":916,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-278","SUBJID":"id-278","SITEID":"CHN-11","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.07981,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-23","TRTSDTM":"2020-08-24 06:55:10","TRTEDTM":"2023-08-25 00:55:10","TRT01SDTM":"2020-08-24 06:55:10","TRT01EDTM":"2022-08-24 18:55:10","TRT02SDTM":"2022-08-24 18:55:10","TRT02EDTM":"2023-08-25 00:55:10","AP01SDTM":"2020-08-24 06:55:10","AP01EDTM":"2022-08-24 18:55:10","AP02SDTM":"2022-08-24 18:55:10","AP02EDTM":"2023-08-25 00:55:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-25","EOSDY":1096,"LSTALVDT":"2023-09-07","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4246,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.68233,"AVALU":"mg/L","BASE2":7.43153,"BASE":9.86462,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.2508,"PCHG2":30.28719,"CHG":-0.18229,"PCHG":-1.84791,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-31 06:55:10","ADY":1071,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-278","SUBJID":"id-278","SITEID":"CHN-11","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.07981,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-23","TRTSDTM":"2020-08-24 06:55:10","TRTEDTM":"2023-08-25 00:55:10","TRT01SDTM":"2020-08-24 06:55:10","TRT01EDTM":"2022-08-24 18:55:10","TRT02SDTM":"2022-08-24 18:55:10","TRT02EDTM":"2023-08-25 00:55:10","AP01SDTM":"2020-08-24 06:55:10","AP01EDTM":"2022-08-24 18:55:10","AP02SDTM":"2022-08-24 18:55:10","AP02EDTM":"2023-08-25 00:55:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-25","EOSDY":1096,"LSTALVDT":"2023-09-07","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7879,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92844,"AVALU":"g/L","BASE2":2.92844,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"4","ADTM":"2020-11-29 06:55:10","ADY":97,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-278","SUBJID":"id-278","SITEID":"CHN-11","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.07981,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-23","TRTSDTM":"2020-08-24 06:55:10","TRTEDTM":"2023-08-25 00:55:10","TRT01SDTM":"2020-08-24 06:55:10","TRT01EDTM":"2022-08-24 18:55:10","TRT02SDTM":"2022-08-24 18:55:10","TRT02EDTM":"2023-08-25 00:55:10","AP01SDTM":"2020-08-24 06:55:10","AP01EDTM":"2022-08-24 18:55:10","AP02SDTM":"2022-08-24 18:55:10","AP02EDTM":"2023-08-25 00:55:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-25","EOSDY":1096,"LSTALVDT":"2023-09-07","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":985,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01044,"AVALU":"g/L","BASE2":2.92844,"BASE":3.01044,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.08201,"PCHG2":2.80035,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"4","BTOXGR":"4","ADTM":"2021-11-02 06:55:10","ADY":435,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-278","SUBJID":"id-278","SITEID":"CHN-11","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.07981,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-23","TRTSDTM":"2020-08-24 06:55:10","TRTEDTM":"2023-08-25 00:55:10","TRT01SDTM":"2020-08-24 06:55:10","TRT01EDTM":"2022-08-24 18:55:10","TRT02SDTM":"2022-08-24 18:55:10","TRT02EDTM":"2023-08-25 00:55:10","AP01SDTM":"2020-08-24 06:55:10","AP01EDTM":"2022-08-24 18:55:10","AP02SDTM":"2022-08-24 18:55:10","AP02EDTM":"2023-08-25 00:55:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-25","EOSDY":1096,"LSTALVDT":"2023-09-07","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1455,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8791,"AVALU":"g/L","BASE2":2.92844,"BASE":3.01044,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04934,"PCHG2":-1.68472,"CHG":-0.13134,"PCHG":-4.36289,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2022-02-14 06:55:10","ADY":539,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-278","SUBJID":"id-278","SITEID":"CHN-11","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.07981,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-23","TRTSDTM":"2020-08-24 06:55:10","TRTEDTM":"2023-08-25 00:55:10","TRT01SDTM":"2020-08-24 06:55:10","TRT01EDTM":"2022-08-24 18:55:10","TRT02SDTM":"2022-08-24 18:55:10","TRT02EDTM":"2023-08-25 00:55:10","AP01SDTM":"2020-08-24 06:55:10","AP01EDTM":"2022-08-24 18:55:10","AP02SDTM":"2022-08-24 18:55:10","AP02EDTM":"2023-08-25 00:55:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-25","EOSDY":1096,"LSTALVDT":"2023-09-07","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1334,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87453,"AVALU":"g/L","BASE2":2.92844,"BASE":3.01044,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05391,"PCHG2":-1.84087,"CHG":-0.13592,"PCHG":-4.51479,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2022-02-23 06:55:10","ADY":548,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-278","SUBJID":"id-278","SITEID":"CHN-11","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.07981,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-23","TRTSDTM":"2020-08-24 06:55:10","TRTEDTM":"2023-08-25 00:55:10","TRT01SDTM":"2020-08-24 06:55:10","TRT01EDTM":"2022-08-24 18:55:10","TRT02SDTM":"2022-08-24 18:55:10","TRT02EDTM":"2023-08-25 00:55:10","AP01SDTM":"2020-08-24 06:55:10","AP01EDTM":"2022-08-24 18:55:10","AP02SDTM":"2022-08-24 18:55:10","AP02EDTM":"2023-08-25 00:55:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-25","EOSDY":1096,"LSTALVDT":"2023-09-07","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7207,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95146,"AVALU":"g/L","BASE2":2.92844,"BASE":3.01044,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02302,"PCHG2":0.78625,"CHG":-0.05898,"PCHG":-1.95923,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2022-05-14 06:55:10","ADY":628,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-278","SUBJID":"id-278","SITEID":"CHN-11","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.07981,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-23","TRTSDTM":"2020-08-24 06:55:10","TRTEDTM":"2023-08-25 00:55:10","TRT01SDTM":"2020-08-24 06:55:10","TRT01EDTM":"2022-08-24 18:55:10","TRT02SDTM":"2022-08-24 18:55:10","TRT02EDTM":"2023-08-25 00:55:10","AP01SDTM":"2020-08-24 06:55:10","AP01EDTM":"2022-08-24 18:55:10","AP02SDTM":"2022-08-24 18:55:10","AP02EDTM":"2023-08-25 00:55:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-25","EOSDY":1096,"LSTALVDT":"2023-09-07","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":169,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05919,"AVALU":"g/L","BASE2":2.92844,"BASE":3.01044,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13076,"PCHG2":4.46511,"CHG":0.04875,"PCHG":1.61941,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"4","BTOXGR":"4","ADTM":"2023-02-26 06:55:10","ADY":916,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-278","SUBJID":"id-278","SITEID":"CHN-11","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":2.07981,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-23","TRTSDTM":"2020-08-24 06:55:10","TRTEDTM":"2023-08-25 00:55:10","TRT01SDTM":"2020-08-24 06:55:10","TRT01EDTM":"2022-08-24 18:55:10","TRT02SDTM":"2022-08-24 18:55:10","TRT02EDTM":"2023-08-25 00:55:10","AP01SDTM":"2020-08-24 06:55:10","AP01EDTM":"2022-08-24 18:55:10","AP02SDTM":"2022-08-24 18:55:10","AP02EDTM":"2023-08-25 00:55:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-25","EOSDY":1096,"LSTALVDT":"2023-09-07","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2114,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95212,"AVALU":"g/L","BASE2":2.92844,"BASE":3.01044,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02368,"PCHG2":0.8086,"CHG":-0.05833,"PCHG":-1.93749,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2023-07-31 06:55:10","ADY":1071,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-289","SUBJID":"id-289","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.91181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-26","TRTSDTM":"2020-09-28 19:05:36","TRTEDTM":"2023-09-29 13:05:36","TRT01SDTM":"2020-09-28 19:05:36","TRT01EDTM":"2022-09-29 07:05:36","TRT02SDTM":"2022-09-29 07:05:36","TRT02EDTM":"2023-09-29 13:05:36","AP01SDTM":"2020-09-28 19:05:36","AP01EDTM":"2022-09-29 07:05:36","AP02SDTM":"2022-09-29 07:05:36","AP02EDTM":"2023-09-29 13:05:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-29","EOSDY":1096,"LSTALVDT":"2023-10-28","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3856,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.14703,"AVALU":"U/L","BASE2":26.14703,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-01 19:05:36","ADY":154,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-289","SUBJID":"id-289","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.91181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-26","TRTSDTM":"2020-09-28 19:05:36","TRTEDTM":"2023-09-29 13:05:36","TRT01SDTM":"2020-09-28 19:05:36","TRT01EDTM":"2022-09-29 07:05:36","TRT02SDTM":"2022-09-29 07:05:36","TRT02EDTM":"2023-09-29 13:05:36","AP01SDTM":"2020-09-28 19:05:36","AP01EDTM":"2022-09-29 07:05:36","AP02SDTM":"2022-09-29 07:05:36","AP02EDTM":"2023-09-29 13:05:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-29","EOSDY":1096,"LSTALVDT":"2023-10-28","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1758,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":39.14535,"AVALU":"U/L","BASE2":26.14703,"BASE":39.14535,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":12.99832,"PCHG2":49.71243,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-05 19:05:36","ADY":280,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-289","SUBJID":"id-289","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.91181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-26","TRTSDTM":"2020-09-28 19:05:36","TRTEDTM":"2023-09-29 13:05:36","TRT01SDTM":"2020-09-28 19:05:36","TRT01EDTM":"2022-09-29 07:05:36","TRT02SDTM":"2022-09-29 07:05:36","TRT02EDTM":"2023-09-29 13:05:36","AP01SDTM":"2020-09-28 19:05:36","AP01EDTM":"2022-09-29 07:05:36","AP02SDTM":"2022-09-29 07:05:36","AP02EDTM":"2023-09-29 13:05:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-29","EOSDY":1096,"LSTALVDT":"2023-10-28","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6576,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.11428,"AVALU":"U/L","BASE2":26.14703,"BASE":39.14535,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.96725,"PCHG2":22.82192,"CHG":-7.03107,"PCHG":-17.96144,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-01 19:05:36","ADY":307,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-289","SUBJID":"id-289","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.91181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-26","TRTSDTM":"2020-09-28 19:05:36","TRTEDTM":"2023-09-29 13:05:36","TRT01SDTM":"2020-09-28 19:05:36","TRT01EDTM":"2022-09-29 07:05:36","TRT02SDTM":"2022-09-29 07:05:36","TRT02EDTM":"2023-09-29 13:05:36","AP01SDTM":"2020-09-28 19:05:36","AP01EDTM":"2022-09-29 07:05:36","AP02SDTM":"2022-09-29 07:05:36","AP02EDTM":"2023-09-29 13:05:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-29","EOSDY":1096,"LSTALVDT":"2023-10-28","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7606,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.22019,"AVALU":"U/L","BASE2":26.14703,"BASE":39.14535,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.92684,"PCHG2":-30.31641,"CHG":-20.92516,"PCHG":-53.45504,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-21 19:05:36","ADY":511,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-289","SUBJID":"id-289","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.91181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-26","TRTSDTM":"2020-09-28 19:05:36","TRTEDTM":"2023-09-29 13:05:36","TRT01SDTM":"2020-09-28 19:05:36","TRT01EDTM":"2022-09-29 07:05:36","TRT02SDTM":"2022-09-29 07:05:36","TRT02EDTM":"2023-09-29 13:05:36","AP01SDTM":"2020-09-28 19:05:36","AP01EDTM":"2022-09-29 07:05:36","AP02SDTM":"2022-09-29 07:05:36","AP02EDTM":"2023-09-29 13:05:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-29","EOSDY":1096,"LSTALVDT":"2023-10-28","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4881,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.20864,"AVALU":"U/L","BASE2":26.14703,"BASE":39.14535,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.93839,"PCHG2":-34.1851,"CHG":-21.93671,"PCHG":-56.03912,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-15 19:05:36","ADY":808,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-289","SUBJID":"id-289","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.91181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-26","TRTSDTM":"2020-09-28 19:05:36","TRTEDTM":"2023-09-29 13:05:36","TRT01SDTM":"2020-09-28 19:05:36","TRT01EDTM":"2022-09-29 07:05:36","TRT02SDTM":"2022-09-29 07:05:36","TRT02EDTM":"2023-09-29 13:05:36","AP01SDTM":"2020-09-28 19:05:36","AP01EDTM":"2022-09-29 07:05:36","AP02SDTM":"2022-09-29 07:05:36","AP02EDTM":"2023-09-29 13:05:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-29","EOSDY":1096,"LSTALVDT":"2023-10-28","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2732,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.37892,"AVALU":"U/L","BASE2":26.14703,"BASE":39.14535,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.76811,"PCHG2":-52.65649,"CHG":-26.76643,"PCHG":-68.37703,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-16 19:05:36","ADY":809,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-289","SUBJID":"id-289","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.91181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-26","TRTSDTM":"2020-09-28 19:05:36","TRTEDTM":"2023-09-29 13:05:36","TRT01SDTM":"2020-09-28 19:05:36","TRT01EDTM":"2022-09-29 07:05:36","TRT02SDTM":"2022-09-29 07:05:36","TRT02EDTM":"2023-09-29 13:05:36","AP01SDTM":"2020-09-28 19:05:36","AP01EDTM":"2022-09-29 07:05:36","AP02SDTM":"2022-09-29 07:05:36","AP02EDTM":"2023-09-29 13:05:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-29","EOSDY":1096,"LSTALVDT":"2023-10-28","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2127,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.38609,"AVALU":"U/L","BASE2":26.14703,"BASE":39.14535,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-22.76093,"PCHG2":-87.0498,"CHG":-35.75926,"PCHG":-91.34995,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2023-08-27 19:05:36","ADY":1063,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-289","SUBJID":"id-289","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.91181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-26","TRTSDTM":"2020-09-28 19:05:36","TRTEDTM":"2023-09-29 13:05:36","TRT01SDTM":"2020-09-28 19:05:36","TRT01EDTM":"2022-09-29 07:05:36","TRT02SDTM":"2022-09-29 07:05:36","TRT02EDTM":"2023-09-29 13:05:36","AP01SDTM":"2020-09-28 19:05:36","AP01EDTM":"2022-09-29 07:05:36","AP02SDTM":"2022-09-29 07:05:36","AP02EDTM":"2023-09-29 13:05:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-29","EOSDY":1096,"LSTALVDT":"2023-10-28","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2125,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.78927,"AVALU":"mg/L","BASE2":7.78927,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-03-01 19:05:36","ADY":154,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-289","SUBJID":"id-289","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.91181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-26","TRTSDTM":"2020-09-28 19:05:36","TRTEDTM":"2023-09-29 13:05:36","TRT01SDTM":"2020-09-28 19:05:36","TRT01EDTM":"2022-09-29 07:05:36","TRT02SDTM":"2022-09-29 07:05:36","TRT02EDTM":"2023-09-29 13:05:36","AP01SDTM":"2020-09-28 19:05:36","AP01EDTM":"2022-09-29 07:05:36","AP02SDTM":"2022-09-29 07:05:36","AP02EDTM":"2023-09-29 13:05:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-29","EOSDY":1096,"LSTALVDT":"2023-10-28","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2800,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.53942,"AVALU":"mg/L","BASE2":7.78927,"BASE":8.53942,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.75015,"PCHG2":9.6306,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-05 19:05:36","ADY":280,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-289","SUBJID":"id-289","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.91181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-26","TRTSDTM":"2020-09-28 19:05:36","TRTEDTM":"2023-09-29 13:05:36","TRT01SDTM":"2020-09-28 19:05:36","TRT01EDTM":"2022-09-29 07:05:36","TRT02SDTM":"2022-09-29 07:05:36","TRT02EDTM":"2023-09-29 13:05:36","AP01SDTM":"2020-09-28 19:05:36","AP01EDTM":"2022-09-29 07:05:36","AP02SDTM":"2022-09-29 07:05:36","AP02EDTM":"2023-09-29 13:05:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-29","EOSDY":1096,"LSTALVDT":"2023-10-28","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5524,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.64946,"AVALU":"mg/L","BASE2":7.78927,"BASE":8.53942,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.86019,"PCHG2":36.71957,"CHG":2.11003,"PCHG":24.70931,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-08-01 19:05:36","ADY":307,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-289","SUBJID":"id-289","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.91181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-26","TRTSDTM":"2020-09-28 19:05:36","TRTEDTM":"2023-09-29 13:05:36","TRT01SDTM":"2020-09-28 19:05:36","TRT01EDTM":"2022-09-29 07:05:36","TRT02SDTM":"2022-09-29 07:05:36","TRT02EDTM":"2023-09-29 13:05:36","AP01SDTM":"2020-09-28 19:05:36","AP01EDTM":"2022-09-29 07:05:36","AP02SDTM":"2022-09-29 07:05:36","AP02EDTM":"2023-09-29 13:05:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-29","EOSDY":1096,"LSTALVDT":"2023-10-28","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6461,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.97367,"AVALU":"mg/L","BASE2":7.78927,"BASE":8.53942,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.1844,"PCHG2":53.72002,"CHG":3.43424,"PCHG":40.21634,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-02-21 19:05:36","ADY":511,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-289","SUBJID":"id-289","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.91181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-26","TRTSDTM":"2020-09-28 19:05:36","TRTEDTM":"2023-09-29 13:05:36","TRT01SDTM":"2020-09-28 19:05:36","TRT01EDTM":"2022-09-29 07:05:36","TRT02SDTM":"2022-09-29 07:05:36","TRT02EDTM":"2023-09-29 13:05:36","AP01SDTM":"2020-09-28 19:05:36","AP01EDTM":"2022-09-29 07:05:36","AP02SDTM":"2022-09-29 07:05:36","AP02EDTM":"2023-09-29 13:05:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-29","EOSDY":1096,"LSTALVDT":"2023-10-28","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":720,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.7392,"AVALU":"mg/L","BASE2":7.78927,"BASE":8.53942,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05007,"PCHG2":-0.64279,"CHG":-0.80022,"PCHG":-9.37092,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-12-15 19:05:36","ADY":808,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-289","SUBJID":"id-289","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.91181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-26","TRTSDTM":"2020-09-28 19:05:36","TRTEDTM":"2023-09-29 13:05:36","TRT01SDTM":"2020-09-28 19:05:36","TRT01EDTM":"2022-09-29 07:05:36","TRT02SDTM":"2022-09-29 07:05:36","TRT02EDTM":"2023-09-29 13:05:36","AP01SDTM":"2020-09-28 19:05:36","AP01EDTM":"2022-09-29 07:05:36","AP02SDTM":"2022-09-29 07:05:36","AP02EDTM":"2023-09-29 13:05:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-29","EOSDY":1096,"LSTALVDT":"2023-10-28","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5077,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.41772,"AVALU":"mg/L","BASE2":7.78927,"BASE":8.53942,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.62845,"PCHG2":20.90635,"CHG":0.8783,"PCHG":10.28523,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-16 19:05:36","ADY":809,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-289","SUBJID":"id-289","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.91181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-26","TRTSDTM":"2020-09-28 19:05:36","TRTEDTM":"2023-09-29 13:05:36","TRT01SDTM":"2020-09-28 19:05:36","TRT01EDTM":"2022-09-29 07:05:36","TRT02SDTM":"2022-09-29 07:05:36","TRT02EDTM":"2023-09-29 13:05:36","AP01SDTM":"2020-09-28 19:05:36","AP01EDTM":"2022-09-29 07:05:36","AP02SDTM":"2022-09-29 07:05:36","AP02EDTM":"2023-09-29 13:05:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-29","EOSDY":1096,"LSTALVDT":"2023-10-28","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2496,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.76125,"AVALU":"mg/L","BASE2":7.78927,"BASE":8.53942,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.97198,"PCHG2":12.47839,"CHG":0.22182,"PCHG":2.59762,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-27 19:05:36","ADY":1063,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-289","SUBJID":"id-289","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.91181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-26","TRTSDTM":"2020-09-28 19:05:36","TRTEDTM":"2023-09-29 13:05:36","TRT01SDTM":"2020-09-28 19:05:36","TRT01EDTM":"2022-09-29 07:05:36","TRT02SDTM":"2022-09-29 07:05:36","TRT02EDTM":"2023-09-29 13:05:36","AP01SDTM":"2020-09-28 19:05:36","AP01EDTM":"2022-09-29 07:05:36","AP02SDTM":"2022-09-29 07:05:36","AP02EDTM":"2023-09-29 13:05:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-29","EOSDY":1096,"LSTALVDT":"2023-10-28","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3691,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89519,"AVALU":"g/L","BASE2":2.89519,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-01 19:05:36","ADY":154,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-289","SUBJID":"id-289","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.91181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-26","TRTSDTM":"2020-09-28 19:05:36","TRTEDTM":"2023-09-29 13:05:36","TRT01SDTM":"2020-09-28 19:05:36","TRT01EDTM":"2022-09-29 07:05:36","TRT02SDTM":"2022-09-29 07:05:36","TRT02EDTM":"2023-09-29 13:05:36","AP01SDTM":"2020-09-28 19:05:36","AP01EDTM":"2022-09-29 07:05:36","AP02SDTM":"2022-09-29 07:05:36","AP02EDTM":"2023-09-29 13:05:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-29","EOSDY":1096,"LSTALVDT":"2023-10-28","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6098,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91442,"AVALU":"g/L","BASE2":2.89519,"BASE":2.91442,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.01923,"PCHG2":0.66409,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-05 19:05:36","ADY":280,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-289","SUBJID":"id-289","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.91181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-26","TRTSDTM":"2020-09-28 19:05:36","TRTEDTM":"2023-09-29 13:05:36","TRT01SDTM":"2020-09-28 19:05:36","TRT01EDTM":"2022-09-29 07:05:36","TRT02SDTM":"2022-09-29 07:05:36","TRT02EDTM":"2023-09-29 13:05:36","AP01SDTM":"2020-09-28 19:05:36","AP01EDTM":"2022-09-29 07:05:36","AP02SDTM":"2022-09-29 07:05:36","AP02EDTM":"2023-09-29 13:05:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-29","EOSDY":1096,"LSTALVDT":"2023-10-28","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7625,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74799,"AVALU":"g/L","BASE2":2.89519,"BASE":2.91442,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1472,"PCHG2":-5.08444,"CHG":-0.16643,"PCHG":-5.71061,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-01 19:05:36","ADY":307,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-289","SUBJID":"id-289","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.91181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-26","TRTSDTM":"2020-09-28 19:05:36","TRTEDTM":"2023-09-29 13:05:36","TRT01SDTM":"2020-09-28 19:05:36","TRT01EDTM":"2022-09-29 07:05:36","TRT02SDTM":"2022-09-29 07:05:36","TRT02EDTM":"2023-09-29 13:05:36","AP01SDTM":"2020-09-28 19:05:36","AP01EDTM":"2022-09-29 07:05:36","AP02SDTM":"2022-09-29 07:05:36","AP02EDTM":"2023-09-29 13:05:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-29","EOSDY":1096,"LSTALVDT":"2023-10-28","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":753,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7032,"AVALU":"g/L","BASE2":2.89519,"BASE":2.91442,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.192,"PCHG2":-6.63159,"CHG":-0.21122,"PCHG":-7.24755,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-21 19:05:36","ADY":511,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-289","SUBJID":"id-289","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.91181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-26","TRTSDTM":"2020-09-28 19:05:36","TRTEDTM":"2023-09-29 13:05:36","TRT01SDTM":"2020-09-28 19:05:36","TRT01EDTM":"2022-09-29 07:05:36","TRT02SDTM":"2022-09-29 07:05:36","TRT02EDTM":"2023-09-29 13:05:36","AP01SDTM":"2020-09-28 19:05:36","AP01EDTM":"2022-09-29 07:05:36","AP02SDTM":"2022-09-29 07:05:36","AP02EDTM":"2023-09-29 13:05:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-29","EOSDY":1096,"LSTALVDT":"2023-10-28","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3787,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95399,"AVALU":"g/L","BASE2":2.89519,"BASE":2.91442,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0588,"PCHG2":2.03082,"CHG":0.03957,"PCHG":1.35771,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-15 19:05:36","ADY":808,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-289","SUBJID":"id-289","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.91181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-26","TRTSDTM":"2020-09-28 19:05:36","TRTEDTM":"2023-09-29 13:05:36","TRT01SDTM":"2020-09-28 19:05:36","TRT01EDTM":"2022-09-29 07:05:36","TRT02SDTM":"2022-09-29 07:05:36","TRT02EDTM":"2023-09-29 13:05:36","AP01SDTM":"2020-09-28 19:05:36","AP01EDTM":"2022-09-29 07:05:36","AP02SDTM":"2022-09-29 07:05:36","AP02EDTM":"2023-09-29 13:05:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-29","EOSDY":1096,"LSTALVDT":"2023-10-28","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":904,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82813,"AVALU":"g/L","BASE2":2.89519,"BASE":2.91442,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06707,"PCHG2":-2.31651,"CHG":-0.08629,"PCHG":-2.96094,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-16 19:05:36","ADY":809,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-289","SUBJID":"id-289","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.91181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-26","TRTSDTM":"2020-09-28 19:05:36","TRTEDTM":"2023-09-29 13:05:36","TRT01SDTM":"2020-09-28 19:05:36","TRT01EDTM":"2022-09-29 07:05:36","TRT02SDTM":"2022-09-29 07:05:36","TRT02EDTM":"2023-09-29 13:05:36","AP01SDTM":"2020-09-28 19:05:36","AP01EDTM":"2022-09-29 07:05:36","AP02SDTM":"2022-09-29 07:05:36","AP02EDTM":"2023-09-29 13:05:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-29","EOSDY":1096,"LSTALVDT":"2023-10-28","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6836,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79318,"AVALU":"g/L","BASE2":2.89519,"BASE":2.91442,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10202,"PCHG2":-3.52361,"CHG":-0.12124,"PCHG":-4.16008,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-27 19:05:36","ADY":1063,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-291","SUBJID":"id-291","SITEID":"CHN-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30136,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 14:17:00","TRTEDTM":"2023-11-01 08:17:00","TRT01SDTM":"2020-10-31 14:17:00","TRT01EDTM":"2022-11-01 02:17:00","TRT02SDTM":"2022-11-01 02:17:00","TRT02EDTM":"2023-11-01 08:17:00","AP01SDTM":"2020-10-31 14:17:00","AP01EDTM":"2022-11-01 02:17:00","AP02SDTM":"2022-11-01 02:17:00","AP02EDTM":"2023-11-01 08:17:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2507,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.47678,"AVALU":"U/L","BASE2":14.47678,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-28 14:17:00","ADY":148,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-291","SUBJID":"id-291","SITEID":"CHN-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30136,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 14:17:00","TRTEDTM":"2023-11-01 08:17:00","TRT01SDTM":"2020-10-31 14:17:00","TRT01EDTM":"2022-11-01 02:17:00","TRT02SDTM":"2022-11-01 02:17:00","TRT02EDTM":"2023-11-01 08:17:00","AP01SDTM":"2020-10-31 14:17:00","AP01EDTM":"2022-11-01 02:17:00","AP02SDTM":"2022-11-01 02:17:00","AP02EDTM":"2023-11-01 08:17:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4774,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.41219,"AVALU":"U/L","BASE2":14.47678,"BASE":18.41219,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":3.93541,"PCHG2":27.18429,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-19 14:17:00","ADY":292,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-291","SUBJID":"id-291","SITEID":"CHN-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30136,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 14:17:00","TRTEDTM":"2023-11-01 08:17:00","TRT01SDTM":"2020-10-31 14:17:00","TRT01EDTM":"2022-11-01 02:17:00","TRT02SDTM":"2022-11-01 02:17:00","TRT02EDTM":"2023-11-01 08:17:00","AP01SDTM":"2020-10-31 14:17:00","AP01EDTM":"2022-11-01 02:17:00","AP02SDTM":"2022-11-01 02:17:00","AP02EDTM":"2023-11-01 08:17:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2604,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.42926,"AVALU":"U/L","BASE2":14.47678,"BASE":18.41219,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.95248,"PCHG2":13.48697,"CHG":-1.98293,"PCHG":-10.76966,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-26 14:17:00","ADY":299,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-291","SUBJID":"id-291","SITEID":"CHN-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30136,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 14:17:00","TRTEDTM":"2023-11-01 08:17:00","TRT01SDTM":"2020-10-31 14:17:00","TRT01EDTM":"2022-11-01 02:17:00","TRT02SDTM":"2022-11-01 02:17:00","TRT02EDTM":"2023-11-01 08:17:00","AP01SDTM":"2020-10-31 14:17:00","AP01EDTM":"2022-11-01 02:17:00","AP02SDTM":"2022-11-01 02:17:00","AP02EDTM":"2023-11-01 08:17:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5545,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.19673,"AVALU":"U/L","BASE2":14.47678,"BASE":18.41219,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.28005,"PCHG2":-22.6573,"CHG":-7.21545,"PCHG":-39.18847,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-13 14:17:00","ADY":408,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-291","SUBJID":"id-291","SITEID":"CHN-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30136,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 14:17:00","TRTEDTM":"2023-11-01 08:17:00","TRT01SDTM":"2020-10-31 14:17:00","TRT01EDTM":"2022-11-01 02:17:00","TRT02SDTM":"2022-11-01 02:17:00","TRT02EDTM":"2023-11-01 08:17:00","AP01SDTM":"2020-10-31 14:17:00","AP01EDTM":"2022-11-01 02:17:00","AP02SDTM":"2022-11-01 02:17:00","AP02EDTM":"2023-11-01 08:17:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1429,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.61358,"AVALU":"U/L","BASE2":14.47678,"BASE":18.41219,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":20.13681,"PCHG2":139.09731,"CHG":16.2014,"PCHG":87.99281,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-31 14:17:00","ADY":516,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-291","SUBJID":"id-291","SITEID":"CHN-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30136,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 14:17:00","TRTEDTM":"2023-11-01 08:17:00","TRT01SDTM":"2020-10-31 14:17:00","TRT01EDTM":"2022-11-01 02:17:00","TRT02SDTM":"2022-11-01 02:17:00","TRT02EDTM":"2023-11-01 08:17:00","AP01SDTM":"2020-10-31 14:17:00","AP01EDTM":"2022-11-01 02:17:00","AP02SDTM":"2022-11-01 02:17:00","AP02EDTM":"2023-11-01 08:17:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":487,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.90682,"AVALU":"U/L","BASE2":14.47678,"BASE":18.41219,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.56996,"PCHG2":-38.47512,"CHG":-9.50537,"PCHG":-51.62541,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-15 14:17:00","ADY":837,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-291","SUBJID":"id-291","SITEID":"CHN-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30136,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 14:17:00","TRTEDTM":"2023-11-01 08:17:00","TRT01SDTM":"2020-10-31 14:17:00","TRT01EDTM":"2022-11-01 02:17:00","TRT02SDTM":"2022-11-01 02:17:00","TRT02EDTM":"2023-11-01 08:17:00","AP01SDTM":"2020-10-31 14:17:00","AP01EDTM":"2022-11-01 02:17:00","AP02SDTM":"2022-11-01 02:17:00","AP02EDTM":"2023-11-01 08:17:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4117,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.66863,"AVALU":"U/L","BASE2":14.47678,"BASE":18.41219,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.80815,"PCHG2":-74.65851,"CHG":-14.74355,"PCHG":-80.07498,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2023-09-04 14:17:00","ADY":1038,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-291","SUBJID":"id-291","SITEID":"CHN-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30136,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 14:17:00","TRTEDTM":"2023-11-01 08:17:00","TRT01SDTM":"2020-10-31 14:17:00","TRT01EDTM":"2022-11-01 02:17:00","TRT02SDTM":"2022-11-01 02:17:00","TRT02EDTM":"2023-11-01 08:17:00","AP01SDTM":"2020-10-31 14:17:00","AP01EDTM":"2022-11-01 02:17:00","AP02SDTM":"2022-11-01 02:17:00","AP02EDTM":"2023-11-01 08:17:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3584,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.9912,"AVALU":"mg/L","BASE2":9.9912,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-28 14:17:00","ADY":148,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-291","SUBJID":"id-291","SITEID":"CHN-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30136,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 14:17:00","TRTEDTM":"2023-11-01 08:17:00","TRT01SDTM":"2020-10-31 14:17:00","TRT01EDTM":"2022-11-01 02:17:00","TRT02SDTM":"2022-11-01 02:17:00","TRT02EDTM":"2023-11-01 08:17:00","AP01SDTM":"2020-10-31 14:17:00","AP01EDTM":"2022-11-01 02:17:00","AP02SDTM":"2022-11-01 02:17:00","AP02EDTM":"2023-11-01 08:17:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8331,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.79995,"AVALU":"mg/L","BASE2":9.9912,"BASE":9.79995,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.19125,"PCHG2":-1.91418,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-19 14:17:00","ADY":292,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-291","SUBJID":"id-291","SITEID":"CHN-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30136,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 14:17:00","TRTEDTM":"2023-11-01 08:17:00","TRT01SDTM":"2020-10-31 14:17:00","TRT01EDTM":"2022-11-01 02:17:00","TRT02SDTM":"2022-11-01 02:17:00","TRT02EDTM":"2023-11-01 08:17:00","AP01SDTM":"2020-10-31 14:17:00","AP01EDTM":"2022-11-01 02:17:00","AP02SDTM":"2022-11-01 02:17:00","AP02EDTM":"2023-11-01 08:17:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1212,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.13237,"AVALU":"mg/L","BASE2":9.9912,"BASE":9.79995,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.85884,"PCHG2":-28.61355,"CHG":-2.66759,"PCHG":-27.22042,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-08-26 14:17:00","ADY":299,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-291","SUBJID":"id-291","SITEID":"CHN-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30136,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 14:17:00","TRTEDTM":"2023-11-01 08:17:00","TRT01SDTM":"2020-10-31 14:17:00","TRT01EDTM":"2022-11-01 02:17:00","TRT02SDTM":"2022-11-01 02:17:00","TRT02EDTM":"2023-11-01 08:17:00","AP01SDTM":"2020-10-31 14:17:00","AP01EDTM":"2022-11-01 02:17:00","AP02SDTM":"2022-11-01 02:17:00","AP02EDTM":"2023-11-01 08:17:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4506,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.15958,"AVALU":"mg/L","BASE2":9.9912,"BASE":9.79995,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.83162,"PCHG2":-8.32353,"CHG":-0.64037,"PCHG":-6.53443,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-13 14:17:00","ADY":408,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-291","SUBJID":"id-291","SITEID":"CHN-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30136,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 14:17:00","TRTEDTM":"2023-11-01 08:17:00","TRT01SDTM":"2020-10-31 14:17:00","TRT01EDTM":"2022-11-01 02:17:00","TRT02SDTM":"2022-11-01 02:17:00","TRT02EDTM":"2023-11-01 08:17:00","AP01SDTM":"2020-10-31 14:17:00","AP01EDTM":"2022-11-01 02:17:00","AP02SDTM":"2022-11-01 02:17:00","AP02EDTM":"2023-11-01 08:17:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4622,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.58855,"AVALU":"mg/L","BASE2":9.9912,"BASE":9.79995,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.59735,"PCHG2":5.97872,"CHG":0.7886,"PCHG":8.04694,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-03-31 14:17:00","ADY":516,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-291","SUBJID":"id-291","SITEID":"CHN-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30136,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 14:17:00","TRTEDTM":"2023-11-01 08:17:00","TRT01SDTM":"2020-10-31 14:17:00","TRT01EDTM":"2022-11-01 02:17:00","TRT02SDTM":"2022-11-01 02:17:00","TRT02EDTM":"2023-11-01 08:17:00","AP01SDTM":"2020-10-31 14:17:00","AP01EDTM":"2022-11-01 02:17:00","AP02SDTM":"2022-11-01 02:17:00","AP02EDTM":"2023-11-01 08:17:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2237,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.80834,"AVALU":"mg/L","BASE2":9.9912,"BASE":9.79995,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18287,"PCHG2":-1.83028,"CHG":0.00838,"PCHG":0.08553,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-15 14:17:00","ADY":837,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-291","SUBJID":"id-291","SITEID":"CHN-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30136,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 14:17:00","TRTEDTM":"2023-11-01 08:17:00","TRT01SDTM":"2020-10-31 14:17:00","TRT01EDTM":"2022-11-01 02:17:00","TRT02SDTM":"2022-11-01 02:17:00","TRT02EDTM":"2023-11-01 08:17:00","AP01SDTM":"2020-10-31 14:17:00","AP01EDTM":"2022-11-01 02:17:00","AP02SDTM":"2022-11-01 02:17:00","AP02EDTM":"2023-11-01 08:17:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7561,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.4387,"AVALU":"mg/L","BASE2":9.9912,"BASE":9.79995,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.5525,"PCHG2":-5.52987,"CHG":-0.36125,"PCHG":-3.68626,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-04 14:17:00","ADY":1038,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-291","SUBJID":"id-291","SITEID":"CHN-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30136,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 14:17:00","TRTEDTM":"2023-11-01 08:17:00","TRT01SDTM":"2020-10-31 14:17:00","TRT01EDTM":"2022-11-01 02:17:00","TRT02SDTM":"2022-11-01 02:17:00","TRT02EDTM":"2023-11-01 08:17:00","AP01SDTM":"2020-10-31 14:17:00","AP01EDTM":"2022-11-01 02:17:00","AP02SDTM":"2022-11-01 02:17:00","AP02EDTM":"2023-11-01 08:17:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2490,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79749,"AVALU":"g/L","BASE2":2.79749,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-28 14:17:00","ADY":148,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-291","SUBJID":"id-291","SITEID":"CHN-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30136,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 14:17:00","TRTEDTM":"2023-11-01 08:17:00","TRT01SDTM":"2020-10-31 14:17:00","TRT01EDTM":"2022-11-01 02:17:00","TRT02SDTM":"2022-11-01 02:17:00","TRT02EDTM":"2023-11-01 08:17:00","AP01SDTM":"2020-10-31 14:17:00","AP01EDTM":"2022-11-01 02:17:00","AP02SDTM":"2022-11-01 02:17:00","AP02EDTM":"2023-11-01 08:17:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3327,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82561,"AVALU":"g/L","BASE2":2.79749,"BASE":2.82561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.02813,"PCHG2":1.00551,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-19 14:17:00","ADY":292,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-291","SUBJID":"id-291","SITEID":"CHN-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30136,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 14:17:00","TRTEDTM":"2023-11-01 08:17:00","TRT01SDTM":"2020-10-31 14:17:00","TRT01EDTM":"2022-11-01 02:17:00","TRT02SDTM":"2022-11-01 02:17:00","TRT02EDTM":"2023-11-01 08:17:00","AP01SDTM":"2020-10-31 14:17:00","AP01EDTM":"2022-11-01 02:17:00","AP02SDTM":"2022-11-01 02:17:00","AP02EDTM":"2023-11-01 08:17:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1462,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91311,"AVALU":"g/L","BASE2":2.79749,"BASE":2.82561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11563,"PCHG2":4.13333,"CHG":0.0875,"PCHG":3.09668,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-26 14:17:00","ADY":299,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-291","SUBJID":"id-291","SITEID":"CHN-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30136,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 14:17:00","TRTEDTM":"2023-11-01 08:17:00","TRT01SDTM":"2020-10-31 14:17:00","TRT01EDTM":"2022-11-01 02:17:00","TRT02SDTM":"2022-11-01 02:17:00","TRT02EDTM":"2023-11-01 08:17:00","AP01SDTM":"2020-10-31 14:17:00","AP01EDTM":"2022-11-01 02:17:00","AP02SDTM":"2022-11-01 02:17:00","AP02EDTM":"2023-11-01 08:17:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":44,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89952,"AVALU":"g/L","BASE2":2.79749,"BASE":2.82561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10204,"PCHG2":3.64741,"CHG":0.07391,"PCHG":2.61559,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-13 14:17:00","ADY":408,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-291","SUBJID":"id-291","SITEID":"CHN-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30136,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 14:17:00","TRTEDTM":"2023-11-01 08:17:00","TRT01SDTM":"2020-10-31 14:17:00","TRT01EDTM":"2022-11-01 02:17:00","TRT02SDTM":"2022-11-01 02:17:00","TRT02EDTM":"2023-11-01 08:17:00","AP01SDTM":"2020-10-31 14:17:00","AP01EDTM":"2022-11-01 02:17:00","AP02SDTM":"2022-11-01 02:17:00","AP02EDTM":"2023-11-01 08:17:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":94,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89468,"AVALU":"g/L","BASE2":2.79749,"BASE":2.82561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09719,"PCHG2":3.47433,"CHG":0.06906,"PCHG":2.44423,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-31 14:17:00","ADY":516,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-291","SUBJID":"id-291","SITEID":"CHN-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30136,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 14:17:00","TRTEDTM":"2023-11-01 08:17:00","TRT01SDTM":"2020-10-31 14:17:00","TRT01EDTM":"2022-11-01 02:17:00","TRT02SDTM":"2022-11-01 02:17:00","TRT02EDTM":"2023-11-01 08:17:00","AP01SDTM":"2020-10-31 14:17:00","AP01EDTM":"2022-11-01 02:17:00","AP02SDTM":"2022-11-01 02:17:00","AP02EDTM":"2023-11-01 08:17:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4494,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92391,"AVALU":"g/L","BASE2":2.79749,"BASE":2.82561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12642,"PCHG2":4.51913,"CHG":0.09829,"PCHG":3.47864,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-15 14:17:00","ADY":837,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-291","SUBJID":"id-291","SITEID":"CHN-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30136,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 14:17:00","TRTEDTM":"2023-11-01 08:17:00","TRT01SDTM":"2020-10-31 14:17:00","TRT01EDTM":"2022-11-01 02:17:00","TRT02SDTM":"2022-11-01 02:17:00","TRT02EDTM":"2023-11-01 08:17:00","AP01SDTM":"2020-10-31 14:17:00","AP01EDTM":"2022-11-01 02:17:00","AP02SDTM":"2022-11-01 02:17:00","AP02EDTM":"2023-11-01 08:17:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7891,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87637,"AVALU":"g/L","BASE2":2.79749,"BASE":2.82561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07889,"PCHG2":2.81987,"CHG":0.05076,"PCHG":1.79629,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-04 14:17:00","ADY":1038,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-298","SUBJID":"id-298","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 15:25:00","TRTEDTM":"2023-03-29 09:25:00","TRT01SDTM":"2020-03-28 15:25:00","TRT01EDTM":"2022-03-29 03:25:00","TRT02SDTM":"2022-03-29 03:25:00","TRT02EDTM":"2023-03-29 09:25:00","AP01SDTM":"2020-03-28 15:25:00","AP01EDTM":"2022-03-29 03:25:00","AP02SDTM":"2022-03-29 03:25:00","AP02EDTM":"2023-03-29 09:25:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-25","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4563,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.88921,"AVALU":"U/L","BASE2":10.88921,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-24 15:25:00","ADY":149,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-298","SUBJID":"id-298","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 15:25:00","TRTEDTM":"2023-03-29 09:25:00","TRT01SDTM":"2020-03-28 15:25:00","TRT01EDTM":"2022-03-29 03:25:00","TRT02SDTM":"2022-03-29 03:25:00","TRT02EDTM":"2023-03-29 09:25:00","AP01SDTM":"2020-03-28 15:25:00","AP01EDTM":"2022-03-29 03:25:00","AP02SDTM":"2022-03-29 03:25:00","AP02EDTM":"2023-03-29 09:25:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-25","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1548,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.2126,"AVALU":"U/L","BASE2":10.88921,"BASE":27.2126,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":16.32339,"PCHG2":149.90433,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-18 15:25:00","ADY":235,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-298","SUBJID":"id-298","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 15:25:00","TRTEDTM":"2023-03-29 09:25:00","TRT01SDTM":"2020-03-28 15:25:00","TRT01EDTM":"2022-03-29 03:25:00","TRT02SDTM":"2022-03-29 03:25:00","TRT02EDTM":"2023-03-29 09:25:00","AP01SDTM":"2020-03-28 15:25:00","AP01EDTM":"2022-03-29 03:25:00","AP02SDTM":"2022-03-29 03:25:00","AP02EDTM":"2023-03-29 09:25:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-25","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3413,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.3719,"AVALU":"U/L","BASE2":10.88921,"BASE":27.2126,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.4827,"PCHG2":13.61621,"CHG":-14.8407,"PCHG":-54.53612,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-06 15:25:00","ADY":343,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-298","SUBJID":"id-298","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 15:25:00","TRTEDTM":"2023-03-29 09:25:00","TRT01SDTM":"2020-03-28 15:25:00","TRT01EDTM":"2022-03-29 03:25:00","TRT02SDTM":"2022-03-29 03:25:00","TRT02EDTM":"2023-03-29 09:25:00","AP01SDTM":"2020-03-28 15:25:00","AP01EDTM":"2022-03-29 03:25:00","AP02SDTM":"2022-03-29 03:25:00","AP02EDTM":"2023-03-29 09:25:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-25","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6765,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.88792,"AVALU":"U/L","BASE2":10.88921,"BASE":27.2126,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00128,"PCHG2":-0.01178,"CHG":-16.32467,"PCHG":-59.9894,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-02 15:25:00","ADY":492,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-298","SUBJID":"id-298","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 15:25:00","TRTEDTM":"2023-03-29 09:25:00","TRT01SDTM":"2020-03-28 15:25:00","TRT01EDTM":"2022-03-29 03:25:00","TRT02SDTM":"2022-03-29 03:25:00","TRT02EDTM":"2023-03-29 09:25:00","AP01SDTM":"2020-03-28 15:25:00","AP01EDTM":"2022-03-29 03:25:00","AP02SDTM":"2022-03-29 03:25:00","AP02EDTM":"2023-03-29 09:25:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-25","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4221,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.18918,"AVALU":"U/L","BASE2":10.88921,"BASE":27.2126,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.70003,"PCHG2":-43.16224,"CHG":-21.02342,"PCHG":-77.25619,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-11-11 15:25:00","ADY":593,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-298","SUBJID":"id-298","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 15:25:00","TRTEDTM":"2023-03-29 09:25:00","TRT01SDTM":"2020-03-28 15:25:00","TRT01EDTM":"2022-03-29 03:25:00","TRT02SDTM":"2022-03-29 03:25:00","TRT02EDTM":"2023-03-29 09:25:00","AP01SDTM":"2020-03-28 15:25:00","AP01EDTM":"2022-03-29 03:25:00","AP02SDTM":"2022-03-29 03:25:00","AP02EDTM":"2023-03-29 09:25:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-25","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":329,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.16869,"AVALU":"U/L","BASE2":10.88921,"BASE":27.2126,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.72052,"PCHG2":-89.26743,"CHG":-26.04391,"PCHG":-95.70533,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-03-06 15:25:00","ADY":708,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-298","SUBJID":"id-298","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 15:25:00","TRTEDTM":"2023-03-29 09:25:00","TRT01SDTM":"2020-03-28 15:25:00","TRT01EDTM":"2022-03-29 03:25:00","TRT02SDTM":"2022-03-29 03:25:00","TRT02EDTM":"2023-03-29 09:25:00","AP01SDTM":"2020-03-28 15:25:00","AP01EDTM":"2022-03-29 03:25:00","AP02SDTM":"2022-03-29 03:25:00","AP02EDTM":"2023-03-29 09:25:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-25","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4704,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.47939,"AVALU":"U/L","BASE2":10.88921,"BASE":27.2126,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.59019,"PCHG2":23.78675,"CHG":-13.7332,"PCHG":-50.46635,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-08 15:25:00","ADY":955,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-298","SUBJID":"id-298","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 15:25:00","TRTEDTM":"2023-03-29 09:25:00","TRT01SDTM":"2020-03-28 15:25:00","TRT01EDTM":"2022-03-29 03:25:00","TRT02SDTM":"2022-03-29 03:25:00","TRT02EDTM":"2023-03-29 09:25:00","AP01SDTM":"2020-03-28 15:25:00","AP01EDTM":"2022-03-29 03:25:00","AP02SDTM":"2022-03-29 03:25:00","AP02EDTM":"2023-03-29 09:25:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-25","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3308,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.28484,"AVALU":"mg/L","BASE2":10.28484,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-08-24 15:25:00","ADY":149,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-298","SUBJID":"id-298","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 15:25:00","TRTEDTM":"2023-03-29 09:25:00","TRT01SDTM":"2020-03-28 15:25:00","TRT01EDTM":"2022-03-29 03:25:00","TRT02SDTM":"2022-03-29 03:25:00","TRT02EDTM":"2023-03-29 09:25:00","AP01SDTM":"2020-03-28 15:25:00","AP01EDTM":"2022-03-29 03:25:00","AP02SDTM":"2022-03-29 03:25:00","AP02EDTM":"2023-03-29 09:25:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-25","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3277,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.70817,"AVALU":"mg/L","BASE2":10.28484,"BASE":9.70817,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.57667,"PCHG2":-5.60695,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-18 15:25:00","ADY":235,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-298","SUBJID":"id-298","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 15:25:00","TRTEDTM":"2023-03-29 09:25:00","TRT01SDTM":"2020-03-28 15:25:00","TRT01EDTM":"2022-03-29 03:25:00","TRT02SDTM":"2022-03-29 03:25:00","TRT02EDTM":"2023-03-29 09:25:00","AP01SDTM":"2020-03-28 15:25:00","AP01EDTM":"2022-03-29 03:25:00","AP02SDTM":"2022-03-29 03:25:00","AP02EDTM":"2023-03-29 09:25:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-25","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4460,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.63982,"AVALU":"mg/L","BASE2":10.28484,"BASE":9.70817,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.64502,"PCHG2":-6.27152,"CHG":-0.06835,"PCHG":-0.70405,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-06 15:25:00","ADY":343,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-298","SUBJID":"id-298","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 15:25:00","TRTEDTM":"2023-03-29 09:25:00","TRT01SDTM":"2020-03-28 15:25:00","TRT01EDTM":"2022-03-29 03:25:00","TRT02SDTM":"2022-03-29 03:25:00","TRT02EDTM":"2023-03-29 09:25:00","AP01SDTM":"2020-03-28 15:25:00","AP01EDTM":"2022-03-29 03:25:00","AP02SDTM":"2022-03-29 03:25:00","AP02EDTM":"2023-03-29 09:25:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-25","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4155,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.37608,"AVALU":"mg/L","BASE2":10.28484,"BASE":9.70817,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.90876,"PCHG2":-8.83591,"CHG":-0.33209,"PCHG":-3.42077,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-02 15:25:00","ADY":492,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-298","SUBJID":"id-298","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 15:25:00","TRTEDTM":"2023-03-29 09:25:00","TRT01SDTM":"2020-03-28 15:25:00","TRT01EDTM":"2022-03-29 03:25:00","TRT02SDTM":"2022-03-29 03:25:00","TRT02EDTM":"2023-03-29 09:25:00","AP01SDTM":"2020-03-28 15:25:00","AP01EDTM":"2022-03-29 03:25:00","AP02SDTM":"2022-03-29 03:25:00","AP02EDTM":"2023-03-29 09:25:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-25","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6405,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.31528,"AVALU":"mg/L","BASE2":10.28484,"BASE":9.70817,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.96956,"PCHG2":-19.15011,"CHG":-1.39289,"PCHG":-14.34762,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-11 15:25:00","ADY":593,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-298","SUBJID":"id-298","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 15:25:00","TRTEDTM":"2023-03-29 09:25:00","TRT01SDTM":"2020-03-28 15:25:00","TRT01EDTM":"2022-03-29 03:25:00","TRT02SDTM":"2022-03-29 03:25:00","TRT02EDTM":"2023-03-29 09:25:00","AP01SDTM":"2020-03-28 15:25:00","AP01EDTM":"2022-03-29 03:25:00","AP02SDTM":"2022-03-29 03:25:00","AP02EDTM":"2023-03-29 09:25:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-25","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":483,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.52001,"AVALU":"mg/L","BASE2":10.28484,"BASE":9.70817,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.76482,"PCHG2":-7.43642,"CHG":-0.18816,"PCHG":-1.93814,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-06 15:25:00","ADY":708,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-298","SUBJID":"id-298","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 15:25:00","TRTEDTM":"2023-03-29 09:25:00","TRT01SDTM":"2020-03-28 15:25:00","TRT01EDTM":"2022-03-29 03:25:00","TRT02SDTM":"2022-03-29 03:25:00","TRT02EDTM":"2023-03-29 09:25:00","AP01SDTM":"2020-03-28 15:25:00","AP01EDTM":"2022-03-29 03:25:00","AP02SDTM":"2022-03-29 03:25:00","AP02EDTM":"2023-03-29 09:25:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-25","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2880,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.8055,"AVALU":"mg/L","BASE2":10.28484,"BASE":9.70817,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.47933,"PCHG2":-14.38365,"CHG":-0.90267,"PCHG":-9.29804,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-08 15:25:00","ADY":955,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-298","SUBJID":"id-298","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 15:25:00","TRTEDTM":"2023-03-29 09:25:00","TRT01SDTM":"2020-03-28 15:25:00","TRT01EDTM":"2022-03-29 03:25:00","TRT02SDTM":"2022-03-29 03:25:00","TRT02EDTM":"2023-03-29 09:25:00","AP01SDTM":"2020-03-28 15:25:00","AP01EDTM":"2022-03-29 03:25:00","AP02SDTM":"2022-03-29 03:25:00","AP02EDTM":"2023-03-29 09:25:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-25","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2279,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95251,"AVALU":"g/L","BASE2":2.95251,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-24 15:25:00","ADY":149,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-298","SUBJID":"id-298","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 15:25:00","TRTEDTM":"2023-03-29 09:25:00","TRT01SDTM":"2020-03-28 15:25:00","TRT01EDTM":"2022-03-29 03:25:00","TRT02SDTM":"2022-03-29 03:25:00","TRT02EDTM":"2023-03-29 09:25:00","AP01SDTM":"2020-03-28 15:25:00","AP01EDTM":"2022-03-29 03:25:00","AP02SDTM":"2022-03-29 03:25:00","AP02EDTM":"2023-03-29 09:25:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-25","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6115,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9113,"AVALU":"g/L","BASE2":2.95251,"BASE":2.9113,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.04121,"PCHG2":-1.39579,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-18 15:25:00","ADY":235,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-298","SUBJID":"id-298","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 15:25:00","TRTEDTM":"2023-03-29 09:25:00","TRT01SDTM":"2020-03-28 15:25:00","TRT01EDTM":"2022-03-29 03:25:00","TRT02SDTM":"2022-03-29 03:25:00","TRT02EDTM":"2023-03-29 09:25:00","AP01SDTM":"2020-03-28 15:25:00","AP01EDTM":"2022-03-29 03:25:00","AP02SDTM":"2022-03-29 03:25:00","AP02EDTM":"2023-03-29 09:25:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-25","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1046,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78736,"AVALU":"g/L","BASE2":2.95251,"BASE":2.9113,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16515,"PCHG2":-5.59343,"CHG":-0.12394,"PCHG":-4.25706,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-06 15:25:00","ADY":343,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-298","SUBJID":"id-298","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 15:25:00","TRTEDTM":"2023-03-29 09:25:00","TRT01SDTM":"2020-03-28 15:25:00","TRT01EDTM":"2022-03-29 03:25:00","TRT02SDTM":"2022-03-29 03:25:00","TRT02EDTM":"2023-03-29 09:25:00","AP01SDTM":"2020-03-28 15:25:00","AP01EDTM":"2022-03-29 03:25:00","AP02SDTM":"2022-03-29 03:25:00","AP02EDTM":"2023-03-29 09:25:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-25","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7537,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.734,"AVALU":"g/L","BASE2":2.95251,"BASE":2.9113,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21851,"PCHG2":-7.40067,"CHG":-0.17729,"PCHG":-6.08988,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-02 15:25:00","ADY":492,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-298","SUBJID":"id-298","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 15:25:00","TRTEDTM":"2023-03-29 09:25:00","TRT01SDTM":"2020-03-28 15:25:00","TRT01EDTM":"2022-03-29 03:25:00","TRT02SDTM":"2022-03-29 03:25:00","TRT02EDTM":"2023-03-29 09:25:00","AP01SDTM":"2020-03-28 15:25:00","AP01EDTM":"2022-03-29 03:25:00","AP02SDTM":"2022-03-29 03:25:00","AP02EDTM":"2023-03-29 09:25:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-25","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1335,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90235,"AVALU":"g/L","BASE2":2.95251,"BASE":2.9113,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05016,"PCHG2":-1.69876,"CHG":-0.00895,"PCHG":-0.30726,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-11 15:25:00","ADY":593,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-298","SUBJID":"id-298","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 15:25:00","TRTEDTM":"2023-03-29 09:25:00","TRT01SDTM":"2020-03-28 15:25:00","TRT01EDTM":"2022-03-29 03:25:00","TRT02SDTM":"2022-03-29 03:25:00","TRT02EDTM":"2023-03-29 09:25:00","AP01SDTM":"2020-03-28 15:25:00","AP01EDTM":"2022-03-29 03:25:00","AP02SDTM":"2022-03-29 03:25:00","AP02EDTM":"2023-03-29 09:25:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-25","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6532,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94972,"AVALU":"g/L","BASE2":2.95251,"BASE":2.9113,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00279,"PCHG2":-0.0945,"CHG":0.03842,"PCHG":1.31971,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-06 15:25:00","ADY":708,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-298","SUBJID":"id-298","SITEID":"CHN-11","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 15:25:00","TRTEDTM":"2023-03-29 09:25:00","TRT01SDTM":"2020-03-28 15:25:00","TRT01EDTM":"2022-03-29 03:25:00","TRT02SDTM":"2022-03-29 03:25:00","TRT02EDTM":"2023-03-29 09:25:00","AP01SDTM":"2020-03-28 15:25:00","AP01EDTM":"2022-03-29 03:25:00","AP02SDTM":"2022-03-29 03:25:00","AP02EDTM":"2023-03-29 09:25:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-25","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":853,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91462,"AVALU":"g/L","BASE2":2.95251,"BASE":2.9113,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03789,"PCHG2":-1.28328,"CHG":0.00332,"PCHG":0.1141,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-08 15:25:00","ADY":955,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-317","SUBJID":"id-317","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.05702,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-19","TRTSDTM":"2020-05-20 22:42:47","TRTEDTM":"2022-02-12 19:25:23","TRT01SDTM":"2020-05-20 22:42:47","TRT01EDTM":"2021-02-12 13:25:23","TRT02SDTM":"2021-02-12 13:25:23","TRT02EDTM":"2022-02-12 19:25:23","AP01SDTM":"2020-05-20 22:42:47","AP01EDTM":"2021-02-12 13:25:23","AP02SDTM":"2021-02-12 13:25:23","AP02EDTM":"2022-02-12 19:25:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":633,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":658,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7932,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.74724,"AVALU":"U/L","BASE2":21.74724,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-25 22:42:47","ADY":281,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-317","SUBJID":"id-317","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.05702,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-19","TRTSDTM":"2020-05-20 22:42:47","TRTEDTM":"2022-02-12 19:25:23","TRT01SDTM":"2020-05-20 22:42:47","TRT01EDTM":"2021-02-12 13:25:23","TRT02SDTM":"2021-02-12 13:25:23","TRT02EDTM":"2022-02-12 19:25:23","AP01SDTM":"2020-05-20 22:42:47","AP01EDTM":"2021-02-12 13:25:23","AP02SDTM":"2021-02-12 13:25:23","AP02EDTM":"2022-02-12 19:25:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":633,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":658,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2735,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.6717,"AVALU":"U/L","BASE2":21.74724,"BASE":24.6717,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.92446,"PCHG2":13.4475,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-14 22:42:47","ADY":298,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-317","SUBJID":"id-317","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.05702,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-19","TRTSDTM":"2020-05-20 22:42:47","TRTEDTM":"2022-02-12 19:25:23","TRT01SDTM":"2020-05-20 22:42:47","TRT01EDTM":"2021-02-12 13:25:23","TRT02SDTM":"2021-02-12 13:25:23","TRT02EDTM":"2022-02-12 19:25:23","AP01SDTM":"2020-05-20 22:42:47","AP01EDTM":"2021-02-12 13:25:23","AP02SDTM":"2021-02-12 13:25:23","AP02EDTM":"2022-02-12 19:25:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":633,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":658,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4438,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.17515,"AVALU":"U/L","BASE2":21.74724,"BASE":24.6717,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.5721,"PCHG2":-16.42551,"CHG":-6.49656,"PCHG":-26.33201,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-25 22:42:47","ADY":340,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-317","SUBJID":"id-317","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.05702,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-19","TRTSDTM":"2020-05-20 22:42:47","TRTEDTM":"2022-02-12 19:25:23","TRT01SDTM":"2020-05-20 22:42:47","TRT01EDTM":"2021-02-12 13:25:23","TRT02SDTM":"2021-02-12 13:25:23","TRT02EDTM":"2022-02-12 19:25:23","AP01SDTM":"2020-05-20 22:42:47","AP01EDTM":"2021-02-12 13:25:23","AP02SDTM":"2021-02-12 13:25:23","AP02EDTM":"2022-02-12 19:25:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":633,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":658,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2403,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.72121,"AVALU":"U/L","BASE2":21.74724,"BASE":24.6717,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.97397,"PCHG2":9.07686,"CHG":-0.95049,"PCHG":-3.85256,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-24 22:42:47","ADY":369,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-317","SUBJID":"id-317","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.05702,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-19","TRTSDTM":"2020-05-20 22:42:47","TRTEDTM":"2022-02-12 19:25:23","TRT01SDTM":"2020-05-20 22:42:47","TRT01EDTM":"2021-02-12 13:25:23","TRT02SDTM":"2021-02-12 13:25:23","TRT02EDTM":"2022-02-12 19:25:23","AP01SDTM":"2020-05-20 22:42:47","AP01EDTM":"2021-02-12 13:25:23","AP02SDTM":"2021-02-12 13:25:23","AP02EDTM":"2022-02-12 19:25:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":633,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":658,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3132,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.69915,"AVALU":"U/L","BASE2":21.74724,"BASE":24.6717,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.04809,"PCHG2":-50.80226,"CHG":-13.97255,"PCHG":-56.63392,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-10 22:42:47","ADY":416,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-317","SUBJID":"id-317","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.05702,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-19","TRTSDTM":"2020-05-20 22:42:47","TRTEDTM":"2022-02-12 19:25:23","TRT01SDTM":"2020-05-20 22:42:47","TRT01EDTM":"2021-02-12 13:25:23","TRT02SDTM":"2021-02-12 13:25:23","TRT02EDTM":"2022-02-12 19:25:23","AP01SDTM":"2020-05-20 22:42:47","AP01EDTM":"2021-02-12 13:25:23","AP02SDTM":"2021-02-12 13:25:23","AP02EDTM":"2022-02-12 19:25:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":633,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":658,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6218,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.90506,"AVALU":"U/L","BASE2":21.74724,"BASE":24.6717,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-19.84218,"PCHG2":-91.23998,"CHG":-22.76664,"PCHG":-92.27835,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-07-13 22:42:47","ADY":419,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-317","SUBJID":"id-317","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.05702,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-19","TRTSDTM":"2020-05-20 22:42:47","TRTEDTM":"2022-02-12 19:25:23","TRT01SDTM":"2020-05-20 22:42:47","TRT01EDTM":"2021-02-12 13:25:23","TRT02SDTM":"2021-02-12 13:25:23","TRT02EDTM":"2022-02-12 19:25:23","AP01SDTM":"2020-05-20 22:42:47","AP01EDTM":"2021-02-12 13:25:23","AP02SDTM":"2021-02-12 13:25:23","AP02EDTM":"2022-02-12 19:25:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":633,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":658,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4987,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.20186,"AVALU":"U/L","BASE2":21.74724,"BASE":24.6717,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.54539,"PCHG2":-48.49069,"CHG":-13.46985,"PCHG":-54.59634,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-11 22:42:47","ADY":479,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-317","SUBJID":"id-317","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.05702,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-19","TRTSDTM":"2020-05-20 22:42:47","TRTEDTM":"2022-02-12 19:25:23","TRT01SDTM":"2020-05-20 22:42:47","TRT01EDTM":"2021-02-12 13:25:23","TRT02SDTM":"2021-02-12 13:25:23","TRT02EDTM":"2022-02-12 19:25:23","AP01SDTM":"2020-05-20 22:42:47","AP01EDTM":"2021-02-12 13:25:23","AP02SDTM":"2021-02-12 13:25:23","AP02EDTM":"2022-02-12 19:25:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":633,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":658,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7660,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.41474,"AVALU":"mg/L","BASE2":8.41474,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-25 22:42:47","ADY":281,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-317","SUBJID":"id-317","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.05702,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-19","TRTSDTM":"2020-05-20 22:42:47","TRTEDTM":"2022-02-12 19:25:23","TRT01SDTM":"2020-05-20 22:42:47","TRT01EDTM":"2021-02-12 13:25:23","TRT02SDTM":"2021-02-12 13:25:23","TRT02EDTM":"2022-02-12 19:25:23","AP01SDTM":"2020-05-20 22:42:47","AP01EDTM":"2021-02-12 13:25:23","AP02SDTM":"2021-02-12 13:25:23","AP02EDTM":"2022-02-12 19:25:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":633,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":658,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6893,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.26166,"AVALU":"mg/L","BASE2":8.41474,"BASE":9.26166,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.84692,"PCHG2":10.06469,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-14 22:42:47","ADY":298,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-317","SUBJID":"id-317","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.05702,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-19","TRTSDTM":"2020-05-20 22:42:47","TRTEDTM":"2022-02-12 19:25:23","TRT01SDTM":"2020-05-20 22:42:47","TRT01EDTM":"2021-02-12 13:25:23","TRT02SDTM":"2021-02-12 13:25:23","TRT02EDTM":"2022-02-12 19:25:23","AP01SDTM":"2020-05-20 22:42:47","AP01EDTM":"2021-02-12 13:25:23","AP02SDTM":"2021-02-12 13:25:23","AP02EDTM":"2022-02-12 19:25:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":633,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":658,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2826,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.97313,"AVALU":"mg/L","BASE2":8.41474,"BASE":9.26166,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.55839,"PCHG2":6.63585,"CHG":-0.28853,"PCHG":-3.1153,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-25 22:42:47","ADY":340,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-317","SUBJID":"id-317","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.05702,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-19","TRTSDTM":"2020-05-20 22:42:47","TRTEDTM":"2022-02-12 19:25:23","TRT01SDTM":"2020-05-20 22:42:47","TRT01EDTM":"2021-02-12 13:25:23","TRT02SDTM":"2021-02-12 13:25:23","TRT02EDTM":"2022-02-12 19:25:23","AP01SDTM":"2020-05-20 22:42:47","AP01EDTM":"2021-02-12 13:25:23","AP02SDTM":"2021-02-12 13:25:23","AP02EDTM":"2022-02-12 19:25:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":633,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":658,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":954,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.21209,"AVALU":"mg/L","BASE2":8.41474,"BASE":9.26166,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.79734,"PCHG2":33.24337,"CHG":1.95043,"PCHG":21.05914,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-05-24 22:42:47","ADY":369,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-317","SUBJID":"id-317","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.05702,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-19","TRTSDTM":"2020-05-20 22:42:47","TRTEDTM":"2022-02-12 19:25:23","TRT01SDTM":"2020-05-20 22:42:47","TRT01EDTM":"2021-02-12 13:25:23","TRT02SDTM":"2021-02-12 13:25:23","TRT02EDTM":"2022-02-12 19:25:23","AP01SDTM":"2020-05-20 22:42:47","AP01EDTM":"2021-02-12 13:25:23","AP02SDTM":"2021-02-12 13:25:23","AP02EDTM":"2022-02-12 19:25:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":633,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":658,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2439,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.40121,"AVALU":"mg/L","BASE2":8.41474,"BASE":9.26166,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01353,"PCHG2":-0.16084,"CHG":-0.86045,"PCHG":-9.29047,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-10 22:42:47","ADY":416,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-317","SUBJID":"id-317","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.05702,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-19","TRTSDTM":"2020-05-20 22:42:47","TRTEDTM":"2022-02-12 19:25:23","TRT01SDTM":"2020-05-20 22:42:47","TRT01EDTM":"2021-02-12 13:25:23","TRT02SDTM":"2021-02-12 13:25:23","TRT02EDTM":"2022-02-12 19:25:23","AP01SDTM":"2020-05-20 22:42:47","AP01EDTM":"2021-02-12 13:25:23","AP02SDTM":"2021-02-12 13:25:23","AP02EDTM":"2022-02-12 19:25:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":633,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":658,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3604,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.44691,"AVALU":"mg/L","BASE2":8.41474,"BASE":9.26166,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.03216,"PCHG2":24.15004,"CHG":1.18525,"PCHG":12.79734,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-07-13 22:42:47","ADY":419,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-317","SUBJID":"id-317","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.05702,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-19","TRTSDTM":"2020-05-20 22:42:47","TRTEDTM":"2022-02-12 19:25:23","TRT01SDTM":"2020-05-20 22:42:47","TRT01EDTM":"2021-02-12 13:25:23","TRT02SDTM":"2021-02-12 13:25:23","TRT02EDTM":"2022-02-12 19:25:23","AP01SDTM":"2020-05-20 22:42:47","AP01EDTM":"2021-02-12 13:25:23","AP02SDTM":"2021-02-12 13:25:23","AP02EDTM":"2022-02-12 19:25:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":633,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":658,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7748,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.70213,"AVALU":"mg/L","BASE2":8.41474,"BASE":9.26166,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.28739,"PCHG2":15.29921,"CHG":0.44047,"PCHG":4.75585,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-11 22:42:47","ADY":479,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-317","SUBJID":"id-317","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.05702,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-19","TRTSDTM":"2020-05-20 22:42:47","TRTEDTM":"2022-02-12 19:25:23","TRT01SDTM":"2020-05-20 22:42:47","TRT01EDTM":"2021-02-12 13:25:23","TRT02SDTM":"2021-02-12 13:25:23","TRT02EDTM":"2022-02-12 19:25:23","AP01SDTM":"2020-05-20 22:42:47","AP01EDTM":"2021-02-12 13:25:23","AP02SDTM":"2021-02-12 13:25:23","AP02EDTM":"2022-02-12 19:25:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":633,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":658,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5820,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89112,"AVALU":"g/L","BASE2":2.89112,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-25 22:42:47","ADY":281,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-317","SUBJID":"id-317","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.05702,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-19","TRTSDTM":"2020-05-20 22:42:47","TRTEDTM":"2022-02-12 19:25:23","TRT01SDTM":"2020-05-20 22:42:47","TRT01EDTM":"2021-02-12 13:25:23","TRT02SDTM":"2021-02-12 13:25:23","TRT02EDTM":"2022-02-12 19:25:23","AP01SDTM":"2020-05-20 22:42:47","AP01EDTM":"2021-02-12 13:25:23","AP02SDTM":"2021-02-12 13:25:23","AP02EDTM":"2022-02-12 19:25:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":633,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":658,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":912,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95378,"AVALU":"g/L","BASE2":2.89112,"BASE":2.95378,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.06266,"PCHG2":2.16742,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-14 22:42:47","ADY":298,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-317","SUBJID":"id-317","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.05702,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-19","TRTSDTM":"2020-05-20 22:42:47","TRTEDTM":"2022-02-12 19:25:23","TRT01SDTM":"2020-05-20 22:42:47","TRT01EDTM":"2021-02-12 13:25:23","TRT02SDTM":"2021-02-12 13:25:23","TRT02EDTM":"2022-02-12 19:25:23","AP01SDTM":"2020-05-20 22:42:47","AP01EDTM":"2021-02-12 13:25:23","AP02SDTM":"2021-02-12 13:25:23","AP02EDTM":"2022-02-12 19:25:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":633,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":658,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7015,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92558,"AVALU":"g/L","BASE2":2.89112,"BASE":2.95378,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03446,"PCHG2":1.19201,"CHG":-0.0282,"PCHG":-0.95471,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-25 22:42:47","ADY":340,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-317","SUBJID":"id-317","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.05702,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-19","TRTSDTM":"2020-05-20 22:42:47","TRTEDTM":"2022-02-12 19:25:23","TRT01SDTM":"2020-05-20 22:42:47","TRT01EDTM":"2021-02-12 13:25:23","TRT02SDTM":"2021-02-12 13:25:23","TRT02EDTM":"2022-02-12 19:25:23","AP01SDTM":"2020-05-20 22:42:47","AP01EDTM":"2021-02-12 13:25:23","AP02SDTM":"2021-02-12 13:25:23","AP02EDTM":"2022-02-12 19:25:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":633,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":658,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6973,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90246,"AVALU":"g/L","BASE2":2.89112,"BASE":2.95378,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01134,"PCHG2":0.39238,"CHG":-0.05132,"PCHG":-1.73738,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-24 22:42:47","ADY":369,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-317","SUBJID":"id-317","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.05702,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-19","TRTSDTM":"2020-05-20 22:42:47","TRTEDTM":"2022-02-12 19:25:23","TRT01SDTM":"2020-05-20 22:42:47","TRT01EDTM":"2021-02-12 13:25:23","TRT02SDTM":"2021-02-12 13:25:23","TRT02EDTM":"2022-02-12 19:25:23","AP01SDTM":"2020-05-20 22:42:47","AP01EDTM":"2021-02-12 13:25:23","AP02SDTM":"2021-02-12 13:25:23","AP02EDTM":"2022-02-12 19:25:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":633,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":658,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4005,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84901,"AVALU":"g/L","BASE2":2.89112,"BASE":2.95378,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04211,"PCHG2":-1.45666,"CHG":-0.10478,"PCHG":-3.54719,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-10 22:42:47","ADY":416,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-317","SUBJID":"id-317","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.05702,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-19","TRTSDTM":"2020-05-20 22:42:47","TRTEDTM":"2022-02-12 19:25:23","TRT01SDTM":"2020-05-20 22:42:47","TRT01EDTM":"2021-02-12 13:25:23","TRT02SDTM":"2021-02-12 13:25:23","TRT02EDTM":"2022-02-12 19:25:23","AP01SDTM":"2020-05-20 22:42:47","AP01EDTM":"2021-02-12 13:25:23","AP02SDTM":"2021-02-12 13:25:23","AP02EDTM":"2022-02-12 19:25:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":633,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":658,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1686,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8539,"AVALU":"g/L","BASE2":2.89112,"BASE":2.95378,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03722,"PCHG2":-1.28739,"CHG":-0.09988,"PCHG":-3.38152,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-13 22:42:47","ADY":419,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-317","SUBJID":"id-317","SITEID":"CHN-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.05702,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-19","TRTSDTM":"2020-05-20 22:42:47","TRTEDTM":"2022-02-12 19:25:23","TRT01SDTM":"2020-05-20 22:42:47","TRT01EDTM":"2021-02-12 13:25:23","TRT02SDTM":"2021-02-12 13:25:23","TRT02EDTM":"2022-02-12 19:25:23","AP01SDTM":"2020-05-20 22:42:47","AP01EDTM":"2021-02-12 13:25:23","AP02SDTM":"2021-02-12 13:25:23","AP02EDTM":"2022-02-12 19:25:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":633,"DCSREAS":"DEATH","DTHDT":"2022-03-10","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-10","DTHADY":658,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7299,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95591,"AVALU":"g/L","BASE2":2.89112,"BASE":2.95378,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06479,"PCHG2":2.24105,"CHG":0.00213,"PCHG":0.07207,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-11 22:42:47","ADY":479,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-318","SUBJID":"id-318","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.39501,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-28 09:37:04","TRTEDTM":"2022-02-16 14:01:19","TRT01SDTM":"2019-08-28 09:37:04","TRT01EDTM":"2021-02-16 08:01:19","TRT02SDTM":"2021-02-16 08:01:19","TRT02EDTM":"2022-02-16 14:01:19","AP01SDTM":"2019-08-28 09:37:04","AP01EDTM":"2021-02-16 08:01:19","AP02SDTM":"2021-02-16 08:01:19","AP02EDTM":"2022-02-16 14:01:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-02-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-24","DTHADY":910,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4326,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.5748,"AVALU":"U/L","BASE2":12.5748,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-07 09:37:04","ADY":40,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-318","SUBJID":"id-318","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.39501,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-28 09:37:04","TRTEDTM":"2022-02-16 14:01:19","TRT01SDTM":"2019-08-28 09:37:04","TRT01EDTM":"2021-02-16 08:01:19","TRT02SDTM":"2021-02-16 08:01:19","TRT02EDTM":"2022-02-16 14:01:19","AP01SDTM":"2019-08-28 09:37:04","AP01EDTM":"2021-02-16 08:01:19","AP02SDTM":"2021-02-16 08:01:19","AP02EDTM":"2022-02-16 14:01:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-02-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-24","DTHADY":910,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1410,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.14279,"AVALU":"U/L","BASE2":12.5748,"BASE":29.14279,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":16.56799,"PCHG2":131.75548,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-12 09:37:04","ADY":106,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-318","SUBJID":"id-318","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.39501,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-28 09:37:04","TRTEDTM":"2022-02-16 14:01:19","TRT01SDTM":"2019-08-28 09:37:04","TRT01EDTM":"2021-02-16 08:01:19","TRT02SDTM":"2021-02-16 08:01:19","TRT02EDTM":"2022-02-16 14:01:19","AP01SDTM":"2019-08-28 09:37:04","AP01EDTM":"2021-02-16 08:01:19","AP02SDTM":"2021-02-16 08:01:19","AP02EDTM":"2022-02-16 14:01:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-02-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-24","DTHADY":910,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":204,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.76331,"AVALU":"U/L","BASE2":12.5748,"BASE":29.14279,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.18851,"PCHG2":49.21362,"CHG":-10.37947,"PCHG":-35.61592,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-15 09:37:04","ADY":109,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-318","SUBJID":"id-318","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.39501,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-28 09:37:04","TRTEDTM":"2022-02-16 14:01:19","TRT01SDTM":"2019-08-28 09:37:04","TRT01EDTM":"2021-02-16 08:01:19","TRT02SDTM":"2021-02-16 08:01:19","TRT02EDTM":"2022-02-16 14:01:19","AP01SDTM":"2019-08-28 09:37:04","AP01EDTM":"2021-02-16 08:01:19","AP02SDTM":"2021-02-16 08:01:19","AP02EDTM":"2022-02-16 14:01:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-02-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-24","DTHADY":910,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4543,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.68387,"AVALU":"U/L","BASE2":12.5748,"BASE":29.14279,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.89093,"PCHG2":-54.79949,"CHG":-23.45891,"PCHG":-80.49646,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-02-10 09:37:04","ADY":166,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-318","SUBJID":"id-318","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.39501,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-28 09:37:04","TRTEDTM":"2022-02-16 14:01:19","TRT01SDTM":"2019-08-28 09:37:04","TRT01EDTM":"2021-02-16 08:01:19","TRT02SDTM":"2021-02-16 08:01:19","TRT02EDTM":"2022-02-16 14:01:19","AP01SDTM":"2019-08-28 09:37:04","AP01EDTM":"2021-02-16 08:01:19","AP02SDTM":"2021-02-16 08:01:19","AP02EDTM":"2022-02-16 14:01:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-02-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-24","DTHADY":910,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3433,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.37001,"AVALU":"U/L","BASE2":12.5748,"BASE":29.14279,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.79521,"PCHG2":157.41966,"CHG":3.22722,"PCHG":11.07382,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-16 09:37:04","ADY":262,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-318","SUBJID":"id-318","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.39501,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-28 09:37:04","TRTEDTM":"2022-02-16 14:01:19","TRT01SDTM":"2019-08-28 09:37:04","TRT01EDTM":"2021-02-16 08:01:19","TRT02SDTM":"2021-02-16 08:01:19","TRT02EDTM":"2022-02-16 14:01:19","AP01SDTM":"2019-08-28 09:37:04","AP01EDTM":"2021-02-16 08:01:19","AP02SDTM":"2021-02-16 08:01:19","AP02EDTM":"2022-02-16 14:01:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-02-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-24","DTHADY":910,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4258,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.74134,"AVALU":"U/L","BASE2":12.5748,"BASE":29.14279,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.83346,"PCHG2":-22.53284,"CHG":-19.40145,"PCHG":-66.57375,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-04 09:37:04","ADY":281,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-318","SUBJID":"id-318","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.39501,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-28 09:37:04","TRTEDTM":"2022-02-16 14:01:19","TRT01SDTM":"2019-08-28 09:37:04","TRT01EDTM":"2021-02-16 08:01:19","TRT02SDTM":"2021-02-16 08:01:19","TRT02EDTM":"2022-02-16 14:01:19","AP01SDTM":"2019-08-28 09:37:04","AP01EDTM":"2021-02-16 08:01:19","AP02SDTM":"2021-02-16 08:01:19","AP02EDTM":"2022-02-16 14:01:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-02-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-24","DTHADY":910,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7744,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.1896,"AVALU":"U/L","BASE2":12.5748,"BASE":29.14279,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.3852,"PCHG2":-98.49226,"CHG":-28.95319,"PCHG":-99.34943,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-05-24 09:37:04","ADY":635,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-318","SUBJID":"id-318","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.39501,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-28 09:37:04","TRTEDTM":"2022-02-16 14:01:19","TRT01SDTM":"2019-08-28 09:37:04","TRT01EDTM":"2021-02-16 08:01:19","TRT02SDTM":"2021-02-16 08:01:19","TRT02EDTM":"2022-02-16 14:01:19","AP01SDTM":"2019-08-28 09:37:04","AP01EDTM":"2021-02-16 08:01:19","AP02SDTM":"2021-02-16 08:01:19","AP02EDTM":"2022-02-16 14:01:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-02-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-24","DTHADY":910,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5087,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.32731,"AVALU":"mg/L","BASE2":9.32731,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2019-10-07 09:37:04","ADY":40,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-318","SUBJID":"id-318","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.39501,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-28 09:37:04","TRTEDTM":"2022-02-16 14:01:19","TRT01SDTM":"2019-08-28 09:37:04","TRT01EDTM":"2021-02-16 08:01:19","TRT02SDTM":"2021-02-16 08:01:19","TRT02EDTM":"2022-02-16 14:01:19","AP01SDTM":"2019-08-28 09:37:04","AP01EDTM":"2021-02-16 08:01:19","AP02SDTM":"2021-02-16 08:01:19","AP02EDTM":"2022-02-16 14:01:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-02-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-24","DTHADY":910,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3754,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.03646,"AVALU":"mg/L","BASE2":9.32731,"BASE":10.03646,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.70915,"PCHG2":7.60291,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2019-12-12 09:37:04","ADY":106,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-318","SUBJID":"id-318","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.39501,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-28 09:37:04","TRTEDTM":"2022-02-16 14:01:19","TRT01SDTM":"2019-08-28 09:37:04","TRT01EDTM":"2021-02-16 08:01:19","TRT02SDTM":"2021-02-16 08:01:19","TRT02EDTM":"2022-02-16 14:01:19","AP01SDTM":"2019-08-28 09:37:04","AP01EDTM":"2021-02-16 08:01:19","AP02SDTM":"2021-02-16 08:01:19","AP02EDTM":"2022-02-16 14:01:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-02-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-24","DTHADY":910,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4189,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.62327,"AVALU":"mg/L","BASE2":9.32731,"BASE":10.03646,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.29596,"PCHG2":3.17301,"CHG":-0.41319,"PCHG":-4.11689,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2019-12-15 09:37:04","ADY":109,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-318","SUBJID":"id-318","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.39501,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-28 09:37:04","TRTEDTM":"2022-02-16 14:01:19","TRT01SDTM":"2019-08-28 09:37:04","TRT01EDTM":"2021-02-16 08:01:19","TRT02SDTM":"2021-02-16 08:01:19","TRT02EDTM":"2022-02-16 14:01:19","AP01SDTM":"2019-08-28 09:37:04","AP01EDTM":"2021-02-16 08:01:19","AP02SDTM":"2021-02-16 08:01:19","AP02EDTM":"2022-02-16 14:01:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-02-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-24","DTHADY":910,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7626,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.8716,"AVALU":"mg/L","BASE2":9.32731,"BASE":10.03646,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.54428,"PCHG2":5.83535,"CHG":-0.16487,"PCHG":-1.64267,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-02-10 09:37:04","ADY":166,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-318","SUBJID":"id-318","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.39501,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-28 09:37:04","TRTEDTM":"2022-02-16 14:01:19","TRT01SDTM":"2019-08-28 09:37:04","TRT01EDTM":"2021-02-16 08:01:19","TRT02SDTM":"2021-02-16 08:01:19","TRT02EDTM":"2022-02-16 14:01:19","AP01SDTM":"2019-08-28 09:37:04","AP01EDTM":"2021-02-16 08:01:19","AP02SDTM":"2021-02-16 08:01:19","AP02EDTM":"2022-02-16 14:01:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-02-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-24","DTHADY":910,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5425,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.67852,"AVALU":"mg/L","BASE2":9.32731,"BASE":10.03646,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.35121,"PCHG2":14.48655,"CHG":0.64206,"PCHG":6.39726,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"1","BTOXGR":"3","ADTM":"2020-05-16 09:37:04","ADY":262,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-318","SUBJID":"id-318","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.39501,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-28 09:37:04","TRTEDTM":"2022-02-16 14:01:19","TRT01SDTM":"2019-08-28 09:37:04","TRT01EDTM":"2021-02-16 08:01:19","TRT02SDTM":"2021-02-16 08:01:19","TRT02EDTM":"2022-02-16 14:01:19","AP01SDTM":"2019-08-28 09:37:04","AP01EDTM":"2021-02-16 08:01:19","AP02SDTM":"2021-02-16 08:01:19","AP02EDTM":"2022-02-16 14:01:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-02-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-24","DTHADY":910,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2764,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.68884,"AVALU":"mg/L","BASE2":9.32731,"BASE":10.03646,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.63848,"PCHG2":-17.56643,"CHG":-2.34762,"PCHG":-23.39095,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-2","BTOXGR":"3","ADTM":"2020-06-04 09:37:04","ADY":281,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-318","SUBJID":"id-318","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.39501,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-28 09:37:04","TRTEDTM":"2022-02-16 14:01:19","TRT01SDTM":"2019-08-28 09:37:04","TRT01EDTM":"2021-02-16 08:01:19","TRT02SDTM":"2021-02-16 08:01:19","TRT02EDTM":"2022-02-16 14:01:19","AP01SDTM":"2019-08-28 09:37:04","AP01EDTM":"2021-02-16 08:01:19","AP02SDTM":"2021-02-16 08:01:19","AP02EDTM":"2022-02-16 14:01:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-02-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-24","DTHADY":910,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1214,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.51704,"AVALU":"mg/L","BASE2":9.32731,"BASE":10.03646,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18972,"PCHG2":2.03406,"CHG":-0.51942,"PCHG":-5.17538,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-05-24 09:37:04","ADY":635,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-318","SUBJID":"id-318","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.39501,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-28 09:37:04","TRTEDTM":"2022-02-16 14:01:19","TRT01SDTM":"2019-08-28 09:37:04","TRT01EDTM":"2021-02-16 08:01:19","TRT02SDTM":"2021-02-16 08:01:19","TRT02EDTM":"2022-02-16 14:01:19","AP01SDTM":"2019-08-28 09:37:04","AP01EDTM":"2021-02-16 08:01:19","AP02SDTM":"2021-02-16 08:01:19","AP02EDTM":"2022-02-16 14:01:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-02-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-24","DTHADY":910,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":158,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82938,"AVALU":"g/L","BASE2":2.82938,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-07 09:37:04","ADY":40,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-318","SUBJID":"id-318","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.39501,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-28 09:37:04","TRTEDTM":"2022-02-16 14:01:19","TRT01SDTM":"2019-08-28 09:37:04","TRT01EDTM":"2021-02-16 08:01:19","TRT02SDTM":"2021-02-16 08:01:19","TRT02EDTM":"2022-02-16 14:01:19","AP01SDTM":"2019-08-28 09:37:04","AP01EDTM":"2021-02-16 08:01:19","AP02SDTM":"2021-02-16 08:01:19","AP02EDTM":"2022-02-16 14:01:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-02-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-24","DTHADY":910,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7792,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85379,"AVALU":"g/L","BASE2":2.82938,"BASE":2.85379,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.02441,"PCHG2":0.8628,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-12 09:37:04","ADY":106,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-318","SUBJID":"id-318","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.39501,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-28 09:37:04","TRTEDTM":"2022-02-16 14:01:19","TRT01SDTM":"2019-08-28 09:37:04","TRT01EDTM":"2021-02-16 08:01:19","TRT02SDTM":"2021-02-16 08:01:19","TRT02EDTM":"2022-02-16 14:01:19","AP01SDTM":"2019-08-28 09:37:04","AP01EDTM":"2021-02-16 08:01:19","AP02SDTM":"2021-02-16 08:01:19","AP02EDTM":"2022-02-16 14:01:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-02-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-24","DTHADY":910,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7675,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86031,"AVALU":"g/L","BASE2":2.82938,"BASE":2.85379,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03094,"PCHG2":1.09336,"CHG":0.00652,"PCHG":0.22859,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-15 09:37:04","ADY":109,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-318","SUBJID":"id-318","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.39501,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-28 09:37:04","TRTEDTM":"2022-02-16 14:01:19","TRT01SDTM":"2019-08-28 09:37:04","TRT01EDTM":"2021-02-16 08:01:19","TRT02SDTM":"2021-02-16 08:01:19","TRT02EDTM":"2022-02-16 14:01:19","AP01SDTM":"2019-08-28 09:37:04","AP01EDTM":"2021-02-16 08:01:19","AP02SDTM":"2021-02-16 08:01:19","AP02EDTM":"2022-02-16 14:01:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-02-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-24","DTHADY":910,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7887,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92547,"AVALU":"g/L","BASE2":2.82938,"BASE":2.85379,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09609,"PCHG2":3.3963,"CHG":0.07168,"PCHG":2.51184,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-10 09:37:04","ADY":166,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-318","SUBJID":"id-318","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.39501,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-28 09:37:04","TRTEDTM":"2022-02-16 14:01:19","TRT01SDTM":"2019-08-28 09:37:04","TRT01EDTM":"2021-02-16 08:01:19","TRT02SDTM":"2021-02-16 08:01:19","TRT02EDTM":"2022-02-16 14:01:19","AP01SDTM":"2019-08-28 09:37:04","AP01EDTM":"2021-02-16 08:01:19","AP02SDTM":"2021-02-16 08:01:19","AP02EDTM":"2022-02-16 14:01:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-02-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-24","DTHADY":910,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8018,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91181,"AVALU":"g/L","BASE2":2.82938,"BASE":2.85379,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08244,"PCHG2":2.91358,"CHG":0.05802,"PCHG":2.03324,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-16 09:37:04","ADY":262,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-318","SUBJID":"id-318","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.39501,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-28 09:37:04","TRTEDTM":"2022-02-16 14:01:19","TRT01SDTM":"2019-08-28 09:37:04","TRT01EDTM":"2021-02-16 08:01:19","TRT02SDTM":"2021-02-16 08:01:19","TRT02EDTM":"2022-02-16 14:01:19","AP01SDTM":"2019-08-28 09:37:04","AP01EDTM":"2021-02-16 08:01:19","AP02SDTM":"2021-02-16 08:01:19","AP02EDTM":"2022-02-16 14:01:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-02-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-24","DTHADY":910,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4300,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89012,"AVALU":"g/L","BASE2":2.82938,"BASE":2.85379,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06074,"PCHG2":2.14694,"CHG":0.03633,"PCHG":1.27316,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-04 09:37:04","ADY":281,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-318","SUBJID":"id-318","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.39501,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-28 09:37:04","TRTEDTM":"2022-02-16 14:01:19","TRT01SDTM":"2019-08-28 09:37:04","TRT01EDTM":"2021-02-16 08:01:19","TRT02SDTM":"2021-02-16 08:01:19","TRT02EDTM":"2022-02-16 14:01:19","AP01SDTM":"2019-08-28 09:37:04","AP01EDTM":"2021-02-16 08:01:19","AP02SDTM":"2021-02-16 08:01:19","AP02EDTM":"2022-02-16 14:01:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-02-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-24","DTHADY":910,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5700,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.10853,"AVALU":"g/L","BASE2":2.82938,"BASE":2.85379,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.27915,"PCHG2":9.8661,"CHG":0.25474,"PCHG":8.92629,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-05-24 09:37:04","ADY":635,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-349","SUBJID":"id-349","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.32398,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-11-11","TRTSDTM":"2020-11-13 19:38:06","TRTEDTM":"2023-11-14 13:38:06","TRT01SDTM":"2020-11-13 19:38:06","TRT01EDTM":"2022-11-14 07:38:06","TRT02SDTM":"2022-11-14 07:38:06","TRT02EDTM":"2023-11-14 13:38:06","AP01SDTM":"2020-11-13 19:38:06","AP01EDTM":"2022-11-14 07:38:06","AP02SDTM":"2022-11-14 07:38:06","AP02EDTM":"2023-11-14 13:38:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-14","EOSDY":1096,"LSTALVDT":"2023-11-29","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7720,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.16019,"AVALU":"U/L","BASE2":27.16019,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-02 19:38:06","ADY":19,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-349","SUBJID":"id-349","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.32398,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-11-11","TRTSDTM":"2020-11-13 19:38:06","TRTEDTM":"2023-11-14 13:38:06","TRT01SDTM":"2020-11-13 19:38:06","TRT01EDTM":"2022-11-14 07:38:06","TRT02SDTM":"2022-11-14 07:38:06","TRT02EDTM":"2023-11-14 13:38:06","AP01SDTM":"2020-11-13 19:38:06","AP01EDTM":"2022-11-14 07:38:06","AP02SDTM":"2022-11-14 07:38:06","AP02EDTM":"2023-11-14 13:38:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-14","EOSDY":1096,"LSTALVDT":"2023-11-29","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2754,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.69771,"AVALU":"U/L","BASE2":27.16019,"BASE":20.69771,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-6.46248,"PCHG2":-23.79395,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-23 19:38:06","ADY":40,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-349","SUBJID":"id-349","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.32398,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-11-11","TRTSDTM":"2020-11-13 19:38:06","TRTEDTM":"2023-11-14 13:38:06","TRT01SDTM":"2020-11-13 19:38:06","TRT01EDTM":"2022-11-14 07:38:06","TRT02SDTM":"2022-11-14 07:38:06","TRT02EDTM":"2023-11-14 13:38:06","AP01SDTM":"2020-11-13 19:38:06","AP01EDTM":"2022-11-14 07:38:06","AP02SDTM":"2022-11-14 07:38:06","AP02EDTM":"2023-11-14 13:38:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-14","EOSDY":1096,"LSTALVDT":"2023-11-29","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2167,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.14735,"AVALU":"U/L","BASE2":27.16019,"BASE":20.69771,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.01285,"PCHG2":-7.41102,"CHG":4.44964,"PCHG":21.49821,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-04 19:38:06","ADY":233,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-349","SUBJID":"id-349","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.32398,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-11-11","TRTSDTM":"2020-11-13 19:38:06","TRTEDTM":"2023-11-14 13:38:06","TRT01SDTM":"2020-11-13 19:38:06","TRT01EDTM":"2022-11-14 07:38:06","TRT02SDTM":"2022-11-14 07:38:06","TRT02EDTM":"2023-11-14 13:38:06","AP01SDTM":"2020-11-13 19:38:06","AP01EDTM":"2022-11-14 07:38:06","AP02SDTM":"2022-11-14 07:38:06","AP02EDTM":"2023-11-14 13:38:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-14","EOSDY":1096,"LSTALVDT":"2023-11-29","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3018,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.41793,"AVALU":"U/L","BASE2":27.16019,"BASE":20.69771,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.74227,"PCHG2":-43.23337,"CHG":-5.27978,"PCHG":-25.50902,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-25 19:38:06","ADY":346,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-349","SUBJID":"id-349","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.32398,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-11-11","TRTSDTM":"2020-11-13 19:38:06","TRTEDTM":"2023-11-14 13:38:06","TRT01SDTM":"2020-11-13 19:38:06","TRT01EDTM":"2022-11-14 07:38:06","TRT02SDTM":"2022-11-14 07:38:06","TRT02EDTM":"2023-11-14 13:38:06","AP01SDTM":"2020-11-13 19:38:06","AP01EDTM":"2022-11-14 07:38:06","AP02SDTM":"2022-11-14 07:38:06","AP02EDTM":"2023-11-14 13:38:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-14","EOSDY":1096,"LSTALVDT":"2023-11-29","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5665,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.83525,"AVALU":"U/L","BASE2":27.16019,"BASE":20.69771,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.67506,"PCHG2":17.2129,"CHG":11.13754,"PCHG":53.8105,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-16 19:38:06","ADY":429,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-349","SUBJID":"id-349","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.32398,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-11-11","TRTSDTM":"2020-11-13 19:38:06","TRTEDTM":"2023-11-14 13:38:06","TRT01SDTM":"2020-11-13 19:38:06","TRT01EDTM":"2022-11-14 07:38:06","TRT02SDTM":"2022-11-14 07:38:06","TRT02EDTM":"2023-11-14 13:38:06","AP01SDTM":"2020-11-13 19:38:06","AP01EDTM":"2022-11-14 07:38:06","AP02SDTM":"2022-11-14 07:38:06","AP02EDTM":"2023-11-14 13:38:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-14","EOSDY":1096,"LSTALVDT":"2023-11-29","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5620,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.907,"AVALU":"U/L","BASE2":27.16019,"BASE":20.69771,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.2532,"PCHG2":-11.97781,"CHG":3.20929,"PCHG":15.50552,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-16 19:38:06","ADY":914,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-349","SUBJID":"id-349","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.32398,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-11-11","TRTSDTM":"2020-11-13 19:38:06","TRTEDTM":"2023-11-14 13:38:06","TRT01SDTM":"2020-11-13 19:38:06","TRT01EDTM":"2022-11-14 07:38:06","TRT02SDTM":"2022-11-14 07:38:06","TRT02EDTM":"2023-11-14 13:38:06","AP01SDTM":"2020-11-13 19:38:06","AP01EDTM":"2022-11-14 07:38:06","AP02SDTM":"2022-11-14 07:38:06","AP02EDTM":"2023-11-14 13:38:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-14","EOSDY":1096,"LSTALVDT":"2023-11-29","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7397,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.72962,"AVALU":"U/L","BASE2":27.16019,"BASE":20.69771,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.43057,"PCHG2":-42.08574,"CHG":-4.96809,"PCHG":-24.00307,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-11-05 19:38:06","ADY":1087,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-349","SUBJID":"id-349","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.32398,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-11-11","TRTSDTM":"2020-11-13 19:38:06","TRTEDTM":"2023-11-14 13:38:06","TRT01SDTM":"2020-11-13 19:38:06","TRT01EDTM":"2022-11-14 07:38:06","TRT02SDTM":"2022-11-14 07:38:06","TRT02EDTM":"2023-11-14 13:38:06","AP01SDTM":"2020-11-13 19:38:06","AP01EDTM":"2022-11-14 07:38:06","AP02SDTM":"2022-11-14 07:38:06","AP02EDTM":"2023-11-14 13:38:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-14","EOSDY":1096,"LSTALVDT":"2023-11-29","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1643,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.92626,"AVALU":"mg/L","BASE2":9.92626,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-02 19:38:06","ADY":19,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-349","SUBJID":"id-349","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.32398,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-11-11","TRTSDTM":"2020-11-13 19:38:06","TRTEDTM":"2023-11-14 13:38:06","TRT01SDTM":"2020-11-13 19:38:06","TRT01EDTM":"2022-11-14 07:38:06","TRT02SDTM":"2022-11-14 07:38:06","TRT02EDTM":"2023-11-14 13:38:06","AP01SDTM":"2020-11-13 19:38:06","AP01EDTM":"2022-11-14 07:38:06","AP02SDTM":"2022-11-14 07:38:06","AP02EDTM":"2023-11-14 13:38:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-14","EOSDY":1096,"LSTALVDT":"2023-11-29","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2869,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.06288,"AVALU":"mg/L","BASE2":9.92626,"BASE":9.06288,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.86338,"PCHG2":-8.69798,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-23 19:38:06","ADY":40,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-349","SUBJID":"id-349","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.32398,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-11-11","TRTSDTM":"2020-11-13 19:38:06","TRTEDTM":"2023-11-14 13:38:06","TRT01SDTM":"2020-11-13 19:38:06","TRT01EDTM":"2022-11-14 07:38:06","TRT02SDTM":"2022-11-14 07:38:06","TRT02EDTM":"2023-11-14 13:38:06","AP01SDTM":"2020-11-13 19:38:06","AP01EDTM":"2022-11-14 07:38:06","AP02SDTM":"2022-11-14 07:38:06","AP02EDTM":"2023-11-14 13:38:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-14","EOSDY":1096,"LSTALVDT":"2023-11-29","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5451,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.58265,"AVALU":"mg/L","BASE2":9.92626,"BASE":9.06288,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.65639,"PCHG2":6.61267,"CHG":1.51977,"PCHG":16.76924,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-07-04 19:38:06","ADY":233,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-349","SUBJID":"id-349","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.32398,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-11-11","TRTSDTM":"2020-11-13 19:38:06","TRTEDTM":"2023-11-14 13:38:06","TRT01SDTM":"2020-11-13 19:38:06","TRT01EDTM":"2022-11-14 07:38:06","TRT02SDTM":"2022-11-14 07:38:06","TRT02EDTM":"2023-11-14 13:38:06","AP01SDTM":"2020-11-13 19:38:06","AP01EDTM":"2022-11-14 07:38:06","AP02SDTM":"2022-11-14 07:38:06","AP02EDTM":"2023-11-14 13:38:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-14","EOSDY":1096,"LSTALVDT":"2023-11-29","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7032,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.97783,"AVALU":"mg/L","BASE2":9.92626,"BASE":9.06288,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05157,"PCHG2":0.51951,"CHG":0.91495,"PCHG":10.0956,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-25 19:38:06","ADY":346,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-349","SUBJID":"id-349","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.32398,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-11-11","TRTSDTM":"2020-11-13 19:38:06","TRTEDTM":"2023-11-14 13:38:06","TRT01SDTM":"2020-11-13 19:38:06","TRT01EDTM":"2022-11-14 07:38:06","TRT02SDTM":"2022-11-14 07:38:06","TRT02EDTM":"2023-11-14 13:38:06","AP01SDTM":"2020-11-13 19:38:06","AP01EDTM":"2022-11-14 07:38:06","AP02SDTM":"2022-11-14 07:38:06","AP02EDTM":"2023-11-14 13:38:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-14","EOSDY":1096,"LSTALVDT":"2023-11-29","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":760,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.12366,"AVALU":"mg/L","BASE2":9.92626,"BASE":9.06288,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.8026,"PCHG2":-8.08563,"CHG":0.06078,"PCHG":0.67069,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-16 19:38:06","ADY":429,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-349","SUBJID":"id-349","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.32398,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-11-11","TRTSDTM":"2020-11-13 19:38:06","TRTEDTM":"2023-11-14 13:38:06","TRT01SDTM":"2020-11-13 19:38:06","TRT01EDTM":"2022-11-14 07:38:06","TRT02SDTM":"2022-11-14 07:38:06","TRT02EDTM":"2023-11-14 13:38:06","AP01SDTM":"2020-11-13 19:38:06","AP01EDTM":"2022-11-14 07:38:06","AP02SDTM":"2022-11-14 07:38:06","AP02EDTM":"2023-11-14 13:38:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-14","EOSDY":1096,"LSTALVDT":"2023-11-29","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":997,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.02013,"AVALU":"mg/L","BASE2":9.92626,"BASE":9.06288,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.90613,"PCHG2":-9.12861,"CHG":-0.04275,"PCHG":-0.47166,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-16 19:38:06","ADY":914,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-349","SUBJID":"id-349","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.32398,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-11-11","TRTSDTM":"2020-11-13 19:38:06","TRTEDTM":"2023-11-14 13:38:06","TRT01SDTM":"2020-11-13 19:38:06","TRT01EDTM":"2022-11-14 07:38:06","TRT02SDTM":"2022-11-14 07:38:06","TRT02EDTM":"2023-11-14 13:38:06","AP01SDTM":"2020-11-13 19:38:06","AP01EDTM":"2022-11-14 07:38:06","AP02SDTM":"2022-11-14 07:38:06","AP02EDTM":"2023-11-14 13:38:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-14","EOSDY":1096,"LSTALVDT":"2023-11-29","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2647,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.36073,"AVALU":"mg/L","BASE2":9.92626,"BASE":9.06288,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.43447,"PCHG2":14.45127,"CHG":2.29785,"PCHG":25.35459,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2023-11-05 19:38:06","ADY":1087,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-349","SUBJID":"id-349","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.32398,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-11-11","TRTSDTM":"2020-11-13 19:38:06","TRTEDTM":"2023-11-14 13:38:06","TRT01SDTM":"2020-11-13 19:38:06","TRT01EDTM":"2022-11-14 07:38:06","TRT02SDTM":"2022-11-14 07:38:06","TRT02EDTM":"2023-11-14 13:38:06","AP01SDTM":"2020-11-13 19:38:06","AP01EDTM":"2022-11-14 07:38:06","AP02SDTM":"2022-11-14 07:38:06","AP02EDTM":"2023-11-14 13:38:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-14","EOSDY":1096,"LSTALVDT":"2023-11-29","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3191,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03531,"AVALU":"g/L","BASE2":3.03531,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-12-02 19:38:06","ADY":19,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-349","SUBJID":"id-349","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.32398,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-11-11","TRTSDTM":"2020-11-13 19:38:06","TRTEDTM":"2023-11-14 13:38:06","TRT01SDTM":"2020-11-13 19:38:06","TRT01EDTM":"2022-11-14 07:38:06","TRT02SDTM":"2022-11-14 07:38:06","TRT02EDTM":"2023-11-14 13:38:06","AP01SDTM":"2020-11-13 19:38:06","AP01EDTM":"2022-11-14 07:38:06","AP02SDTM":"2022-11-14 07:38:06","AP02EDTM":"2023-11-14 13:38:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-14","EOSDY":1096,"LSTALVDT":"2023-11-29","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5653,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79753,"AVALU":"g/L","BASE2":3.03531,"BASE":2.79753,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.23778,"PCHG2":-7.8338,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-23 19:38:06","ADY":40,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-349","SUBJID":"id-349","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.32398,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-11-11","TRTSDTM":"2020-11-13 19:38:06","TRTEDTM":"2023-11-14 13:38:06","TRT01SDTM":"2020-11-13 19:38:06","TRT01EDTM":"2022-11-14 07:38:06","TRT02SDTM":"2022-11-14 07:38:06","TRT02EDTM":"2023-11-14 13:38:06","AP01SDTM":"2020-11-13 19:38:06","AP01EDTM":"2022-11-14 07:38:06","AP02SDTM":"2022-11-14 07:38:06","AP02EDTM":"2023-11-14 13:38:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-14","EOSDY":1096,"LSTALVDT":"2023-11-29","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3683,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93516,"AVALU":"g/L","BASE2":3.03531,"BASE":2.79753,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10015,"PCHG2":-3.29958,"CHG":0.13763,"PCHG":4.91962,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-04 19:38:06","ADY":233,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-349","SUBJID":"id-349","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.32398,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-11-11","TRTSDTM":"2020-11-13 19:38:06","TRTEDTM":"2023-11-14 13:38:06","TRT01SDTM":"2020-11-13 19:38:06","TRT01EDTM":"2022-11-14 07:38:06","TRT02SDTM":"2022-11-14 07:38:06","TRT02EDTM":"2023-11-14 13:38:06","AP01SDTM":"2020-11-13 19:38:06","AP01EDTM":"2022-11-14 07:38:06","AP02SDTM":"2022-11-14 07:38:06","AP02EDTM":"2023-11-14 13:38:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-14","EOSDY":1096,"LSTALVDT":"2023-11-29","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6569,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98344,"AVALU":"g/L","BASE2":3.03531,"BASE":2.79753,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05187,"PCHG2":-1.70896,"CHG":0.18591,"PCHG":6.64543,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-25 19:38:06","ADY":346,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-349","SUBJID":"id-349","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.32398,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-11-11","TRTSDTM":"2020-11-13 19:38:06","TRTEDTM":"2023-11-14 13:38:06","TRT01SDTM":"2020-11-13 19:38:06","TRT01EDTM":"2022-11-14 07:38:06","TRT02SDTM":"2022-11-14 07:38:06","TRT02EDTM":"2023-11-14 13:38:06","AP01SDTM":"2020-11-13 19:38:06","AP01EDTM":"2022-11-14 07:38:06","AP02SDTM":"2022-11-14 07:38:06","AP02EDTM":"2023-11-14 13:38:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-14","EOSDY":1096,"LSTALVDT":"2023-11-29","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5318,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87007,"AVALU":"g/L","BASE2":3.03531,"BASE":2.79753,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16525,"PCHG2":-5.44417,"CHG":0.07253,"PCHG":2.59274,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-16 19:38:06","ADY":429,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-349","SUBJID":"id-349","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.32398,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-11-11","TRTSDTM":"2020-11-13 19:38:06","TRTEDTM":"2023-11-14 13:38:06","TRT01SDTM":"2020-11-13 19:38:06","TRT01EDTM":"2022-11-14 07:38:06","TRT02SDTM":"2022-11-14 07:38:06","TRT02EDTM":"2023-11-14 13:38:06","AP01SDTM":"2020-11-13 19:38:06","AP01EDTM":"2022-11-14 07:38:06","AP02SDTM":"2022-11-14 07:38:06","AP02EDTM":"2023-11-14 13:38:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-14","EOSDY":1096,"LSTALVDT":"2023-11-29","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5822,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00302,"AVALU":"g/L","BASE2":3.03531,"BASE":2.79753,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03229,"PCHG2":-1.06381,"CHG":0.20549,"PCHG":7.34541,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2023-05-16 19:38:06","ADY":914,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-349","SUBJID":"id-349","SITEID":"CHN-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.32398,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-11-11","TRTSDTM":"2020-11-13 19:38:06","TRTEDTM":"2023-11-14 13:38:06","TRT01SDTM":"2020-11-13 19:38:06","TRT01EDTM":"2022-11-14 07:38:06","TRT02SDTM":"2022-11-14 07:38:06","TRT02EDTM":"2023-11-14 13:38:06","AP01SDTM":"2020-11-13 19:38:06","AP01EDTM":"2022-11-14 07:38:06","AP02SDTM":"2022-11-14 07:38:06","AP02EDTM":"2023-11-14 13:38:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-14","EOSDY":1096,"LSTALVDT":"2023-11-29","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5824,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04919,"AVALU":"g/L","BASE2":3.03531,"BASE":2.79753,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01388,"PCHG2":0.45716,"CHG":0.25166,"PCHG":8.99566,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2023-11-05 19:38:06","ADY":1087,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-354","SUBJID":"id-354","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.59138,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-07","TRTSDTM":"2020-02-10 04:49:15","TRT01SDTM":"2020-02-10 04:49:15","AP01SDTM":"2020-02-10 04:49:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5772,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.41158,"AVALU":"U/L","BASE2":32.41158,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-24 04:49:15","ADY":74,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-354","SUBJID":"id-354","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.59138,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-07","TRTSDTM":"2020-02-10 04:49:15","TRT01SDTM":"2020-02-10 04:49:15","AP01SDTM":"2020-02-10 04:49:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":394,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.60564,"AVALU":"U/L","BASE2":32.41158,"BASE":7.60564,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-24.80594,"PCHG2":-76.53419,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-27 04:49:15","ADY":199,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-354","SUBJID":"id-354","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.59138,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-07","TRTSDTM":"2020-02-10 04:49:15","TRT01SDTM":"2020-02-10 04:49:15","AP01SDTM":"2020-02-10 04:49:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3515,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.29529,"AVALU":"U/L","BASE2":32.41158,"BASE":7.60564,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.11629,"PCHG2":-28.12664,"CHG":15.68965,"PCHG":206.28963,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-12 04:49:15","ADY":457,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-354","SUBJID":"id-354","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.59138,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-07","TRTSDTM":"2020-02-10 04:49:15","TRT01SDTM":"2020-02-10 04:49:15","AP01SDTM":"2020-02-10 04:49:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5204,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.86001,"AVALU":"U/L","BASE2":32.41158,"BASE":7.60564,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-19.55157,"PCHG2":-60.32279,"CHG":5.25437,"PCHG":69.08517,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-22 04:49:15","ADY":467,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-354","SUBJID":"id-354","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.59138,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-07","TRTSDTM":"2020-02-10 04:49:15","TRT01SDTM":"2020-02-10 04:49:15","AP01SDTM":"2020-02-10 04:49:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6260,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.80737,"AVALU":"U/L","BASE2":32.41158,"BASE":7.60564,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.6042,"PCHG2":-14.20543,"CHG":20.20173,"PCHG":265.61512,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-13 04:49:15","ADY":581,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-354","SUBJID":"id-354","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.59138,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-07","TRTSDTM":"2020-02-10 04:49:15","TRT01SDTM":"2020-02-10 04:49:15","AP01SDTM":"2020-02-10 04:49:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8229,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.53061,"AVALU":"U/L","BASE2":32.41158,"BASE":7.60564,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-28.88097,"PCHG2":-89.10696,"CHG":-4.07504,"PCHG":-53.57912,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-12-31 04:49:15","ADY":690,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-354","SUBJID":"id-354","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.59138,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-07","TRTSDTM":"2020-02-10 04:49:15","TRT01SDTM":"2020-02-10 04:49:15","AP01SDTM":"2020-02-10 04:49:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6473,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.45539,"AVALU":"U/L","BASE2":32.41158,"BASE":7.60564,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.95619,"PCHG2":-15.29142,"CHG":19.84974,"PCHG":260.98715,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-23 04:49:15","ADY":713,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-354","SUBJID":"id-354","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.59138,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-07","TRTSDTM":"2020-02-10 04:49:15","TRT01SDTM":"2020-02-10 04:49:15","AP01SDTM":"2020-02-10 04:49:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7292,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.11388,"AVALU":"mg/L","BASE2":9.11388,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-24 04:49:15","ADY":74,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-354","SUBJID":"id-354","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.59138,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-07","TRTSDTM":"2020-02-10 04:49:15","TRT01SDTM":"2020-02-10 04:49:15","AP01SDTM":"2020-02-10 04:49:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3073,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.63448,"AVALU":"mg/L","BASE2":9.11388,"BASE":9.63448,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.5206,"PCHG2":5.71218,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-27 04:49:15","ADY":199,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-354","SUBJID":"id-354","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.59138,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-07","TRTSDTM":"2020-02-10 04:49:15","TRT01SDTM":"2020-02-10 04:49:15","AP01SDTM":"2020-02-10 04:49:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2518,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.1341,"AVALU":"mg/L","BASE2":9.11388,"BASE":9.63448,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02023,"PCHG2":0.22193,"CHG":-0.50037,"PCHG":-5.19358,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-12 04:49:15","ADY":457,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-354","SUBJID":"id-354","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.59138,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-07","TRTSDTM":"2020-02-10 04:49:15","TRT01SDTM":"2020-02-10 04:49:15","AP01SDTM":"2020-02-10 04:49:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4562,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.12906,"AVALU":"mg/L","BASE2":9.11388,"BASE":9.63448,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01518,"PCHG2":0.16657,"CHG":-0.50542,"PCHG":-5.24596,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-22 04:49:15","ADY":467,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-354","SUBJID":"id-354","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.59138,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-07","TRTSDTM":"2020-02-10 04:49:15","TRT01SDTM":"2020-02-10 04:49:15","AP01SDTM":"2020-02-10 04:49:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6546,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.45868,"AVALU":"mg/L","BASE2":9.11388,"BASE":9.63448,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.6552,"PCHG2":-7.189,"CHG":-1.1758,"PCHG":-12.20406,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-13 04:49:15","ADY":581,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-354","SUBJID":"id-354","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.59138,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-07","TRTSDTM":"2020-02-10 04:49:15","TRT01SDTM":"2020-02-10 04:49:15","AP01SDTM":"2020-02-10 04:49:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1251,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.42551,"AVALU":"mg/L","BASE2":9.11388,"BASE":9.63448,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.68837,"PCHG2":-7.55298,"CHG":-1.20897,"PCHG":-12.54838,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-31 04:49:15","ADY":690,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-354","SUBJID":"id-354","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.59138,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-07","TRTSDTM":"2020-02-10 04:49:15","TRT01SDTM":"2020-02-10 04:49:15","AP01SDTM":"2020-02-10 04:49:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5523,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.81218,"AVALU":"mg/L","BASE2":9.11388,"BASE":9.63448,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.69831,"PCHG2":7.66201,"CHG":0.1777,"PCHG":1.84446,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-23 04:49:15","ADY":713,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-354","SUBJID":"id-354","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.59138,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-07","TRTSDTM":"2020-02-10 04:49:15","TRT01SDTM":"2020-02-10 04:49:15","AP01SDTM":"2020-02-10 04:49:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1088,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94532,"AVALU":"g/L","BASE2":2.94532,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-24 04:49:15","ADY":74,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-354","SUBJID":"id-354","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.59138,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-07","TRTSDTM":"2020-02-10 04:49:15","TRT01SDTM":"2020-02-10 04:49:15","AP01SDTM":"2020-02-10 04:49:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2495,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78008,"AVALU":"g/L","BASE2":2.94532,"BASE":2.78008,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.16524,"PCHG2":-5.6102,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-27 04:49:15","ADY":199,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-354","SUBJID":"id-354","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.59138,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-07","TRTSDTM":"2020-02-10 04:49:15","TRT01SDTM":"2020-02-10 04:49:15","AP01SDTM":"2020-02-10 04:49:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4178,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9245,"AVALU":"g/L","BASE2":2.94532,"BASE":2.78008,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02082,"PCHG2":-0.7068,"CHG":0.14442,"PCHG":5.19484,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-12 04:49:15","ADY":457,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-354","SUBJID":"id-354","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.59138,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-07","TRTSDTM":"2020-02-10 04:49:15","TRT01SDTM":"2020-02-10 04:49:15","AP01SDTM":"2020-02-10 04:49:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":252,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86915,"AVALU":"g/L","BASE2":2.94532,"BASE":2.78008,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07617,"PCHG2":-2.58609,"CHG":0.08907,"PCHG":3.20386,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-22 04:49:15","ADY":467,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-354","SUBJID":"id-354","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.59138,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-07","TRTSDTM":"2020-02-10 04:49:15","TRT01SDTM":"2020-02-10 04:49:15","AP01SDTM":"2020-02-10 04:49:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":950,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82744,"AVALU":"g/L","BASE2":2.94532,"BASE":2.78008,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11788,"PCHG2":-4.00226,"CHG":0.04736,"PCHG":1.70351,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-13 04:49:15","ADY":581,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-354","SUBJID":"id-354","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.59138,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-07","TRTSDTM":"2020-02-10 04:49:15","TRT01SDTM":"2020-02-10 04:49:15","AP01SDTM":"2020-02-10 04:49:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":549,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93515,"AVALU":"g/L","BASE2":2.94532,"BASE":2.78008,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01017,"PCHG2":-0.34529,"CHG":0.15507,"PCHG":5.57784,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-31 04:49:15","ADY":690,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-354","SUBJID":"id-354","SITEID":"CHN-11","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.59138,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-07","TRTSDTM":"2020-02-10 04:49:15","TRT01SDTM":"2020-02-10 04:49:15","AP01SDTM":"2020-02-10 04:49:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5566,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87722,"AVALU":"g/L","BASE2":2.94532,"BASE":2.78008,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0681,"PCHG2":-2.31214,"CHG":0.09714,"PCHG":3.49409,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-23 04:49:15","ADY":713,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-356","SUBJID":"id-356","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.24981,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 10:37:13","TRTEDTM":"2022-02-12 14:59:13","TRT01SDTM":"2020-03-12 10:37:13","TRT01EDTM":"2021-02-12 08:59:13","TRT02SDTM":"2021-02-12 08:59:13","TRT02EDTM":"2022-02-12 14:59:13","AP01SDTM":"2020-03-12 10:37:13","AP01EDTM":"2021-02-12 08:59:13","AP02SDTM":"2021-02-12 08:59:13","AP02EDTM":"2022-02-12 14:59:13","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":703,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-22","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":414,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.42241,"AVALU":"U/L","BASE2":24.42241,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-08 10:37:13","ADY":88,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-356","SUBJID":"id-356","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.24981,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 10:37:13","TRTEDTM":"2022-02-12 14:59:13","TRT01SDTM":"2020-03-12 10:37:13","TRT01EDTM":"2021-02-12 08:59:13","TRT02SDTM":"2021-02-12 08:59:13","TRT02EDTM":"2022-02-12 14:59:13","AP01SDTM":"2020-03-12 10:37:13","AP01EDTM":"2021-02-12 08:59:13","AP02SDTM":"2021-02-12 08:59:13","AP02EDTM":"2022-02-12 14:59:13","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":703,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-22","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3781,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.92569,"AVALU":"U/L","BASE2":24.42241,"BASE":30.92569,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":6.50327,"PCHG2":26.6283,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-08 10:37:13","ADY":149,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-356","SUBJID":"id-356","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.24981,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 10:37:13","TRTEDTM":"2022-02-12 14:59:13","TRT01SDTM":"2020-03-12 10:37:13","TRT01EDTM":"2021-02-12 08:59:13","TRT02SDTM":"2021-02-12 08:59:13","TRT02EDTM":"2022-02-12 14:59:13","AP01SDTM":"2020-03-12 10:37:13","AP01EDTM":"2021-02-12 08:59:13","AP02SDTM":"2021-02-12 08:59:13","AP02EDTM":"2022-02-12 14:59:13","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":703,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-22","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3130,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.52733,"AVALU":"U/L","BASE2":24.42241,"BASE":30.92569,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.89508,"PCHG2":-36.42181,"CHG":-15.39836,"PCHG":-49.79148,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-31 10:37:13","ADY":294,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-356","SUBJID":"id-356","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.24981,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 10:37:13","TRTEDTM":"2022-02-12 14:59:13","TRT01SDTM":"2020-03-12 10:37:13","TRT01EDTM":"2021-02-12 08:59:13","TRT02SDTM":"2021-02-12 08:59:13","TRT02EDTM":"2022-02-12 14:59:13","AP01SDTM":"2020-03-12 10:37:13","AP01EDTM":"2021-02-12 08:59:13","AP02SDTM":"2021-02-12 08:59:13","AP02EDTM":"2022-02-12 14:59:13","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":703,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-22","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2178,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.0232,"AVALU":"U/L","BASE2":24.42241,"BASE":30.92569,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.60078,"PCHG2":2.45997,"CHG":-5.90249,"PCHG":-19.08604,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-16 10:37:13","ADY":430,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-356","SUBJID":"id-356","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.24981,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 10:37:13","TRTEDTM":"2022-02-12 14:59:13","TRT01SDTM":"2020-03-12 10:37:13","TRT01EDTM":"2021-02-12 08:59:13","TRT02SDTM":"2021-02-12 08:59:13","TRT02EDTM":"2022-02-12 14:59:13","AP01SDTM":"2020-03-12 10:37:13","AP01EDTM":"2021-02-12 08:59:13","AP02SDTM":"2021-02-12 08:59:13","AP02EDTM":"2022-02-12 14:59:13","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":703,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-22","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7056,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.12284,"AVALU":"U/L","BASE2":24.42241,"BASE":30.92569,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.29957,"PCHG2":-38.07802,"CHG":-15.80284,"PCHG":-51.09941,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-11 10:37:13","ADY":517,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-356","SUBJID":"id-356","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.24981,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 10:37:13","TRTEDTM":"2022-02-12 14:59:13","TRT01SDTM":"2020-03-12 10:37:13","TRT01EDTM":"2021-02-12 08:59:13","TRT02SDTM":"2021-02-12 08:59:13","TRT02EDTM":"2022-02-12 14:59:13","AP01SDTM":"2020-03-12 10:37:13","AP01EDTM":"2021-02-12 08:59:13","AP02SDTM":"2021-02-12 08:59:13","AP02EDTM":"2022-02-12 14:59:13","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":703,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-22","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3550,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.7516,"AVALU":"U/L","BASE2":24.42241,"BASE":30.92569,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.67082,"PCHG2":-15.03052,"CHG":-10.17409,"PCHG":-32.89851,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-18 10:37:13","ADY":555,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-356","SUBJID":"id-356","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.24981,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 10:37:13","TRTEDTM":"2022-02-12 14:59:13","TRT01SDTM":"2020-03-12 10:37:13","TRT01EDTM":"2021-02-12 08:59:13","TRT02SDTM":"2021-02-12 08:59:13","TRT02EDTM":"2022-02-12 14:59:13","AP01SDTM":"2020-03-12 10:37:13","AP01EDTM":"2021-02-12 08:59:13","AP02SDTM":"2021-02-12 08:59:13","AP02EDTM":"2022-02-12 14:59:13","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":703,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-22","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2089,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.64568,"AVALU":"U/L","BASE2":24.42241,"BASE":30.92569,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.77674,"PCHG2":-15.46423,"CHG":-10.28001,"PCHG":-33.24101,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-25 10:37:13","ADY":623,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-356","SUBJID":"id-356","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.24981,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 10:37:13","TRTEDTM":"2022-02-12 14:59:13","TRT01SDTM":"2020-03-12 10:37:13","TRT01EDTM":"2021-02-12 08:59:13","TRT02SDTM":"2021-02-12 08:59:13","TRT02EDTM":"2022-02-12 14:59:13","AP01SDTM":"2020-03-12 10:37:13","AP01EDTM":"2021-02-12 08:59:13","AP02SDTM":"2021-02-12 08:59:13","AP02EDTM":"2022-02-12 14:59:13","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":703,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-22","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4099,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.30935,"AVALU":"mg/L","BASE2":9.30935,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-08 10:37:13","ADY":88,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-356","SUBJID":"id-356","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.24981,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 10:37:13","TRTEDTM":"2022-02-12 14:59:13","TRT01SDTM":"2020-03-12 10:37:13","TRT01EDTM":"2021-02-12 08:59:13","TRT02SDTM":"2021-02-12 08:59:13","TRT02EDTM":"2022-02-12 14:59:13","AP01SDTM":"2020-03-12 10:37:13","AP01EDTM":"2021-02-12 08:59:13","AP02SDTM":"2021-02-12 08:59:13","AP02EDTM":"2022-02-12 14:59:13","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":703,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-22","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6129,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.69398,"AVALU":"mg/L","BASE2":9.30935,"BASE":9.69398,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.38463,"PCHG2":4.13169,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-08 10:37:13","ADY":149,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-356","SUBJID":"id-356","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.24981,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 10:37:13","TRTEDTM":"2022-02-12 14:59:13","TRT01SDTM":"2020-03-12 10:37:13","TRT01EDTM":"2021-02-12 08:59:13","TRT02SDTM":"2021-02-12 08:59:13","TRT02EDTM":"2022-02-12 14:59:13","AP01SDTM":"2020-03-12 10:37:13","AP01EDTM":"2021-02-12 08:59:13","AP02SDTM":"2021-02-12 08:59:13","AP02EDTM":"2022-02-12 14:59:13","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":703,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-22","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5530,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.37848,"AVALU":"mg/L","BASE2":9.30935,"BASE":9.69398,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.93087,"PCHG2":-9.99935,"CHG":-1.31551,"PCHG":-13.57036,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-31 10:37:13","ADY":294,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-356","SUBJID":"id-356","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.24981,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 10:37:13","TRTEDTM":"2022-02-12 14:59:13","TRT01SDTM":"2020-03-12 10:37:13","TRT01EDTM":"2021-02-12 08:59:13","TRT02SDTM":"2021-02-12 08:59:13","TRT02EDTM":"2022-02-12 14:59:13","AP01SDTM":"2020-03-12 10:37:13","AP01EDTM":"2021-02-12 08:59:13","AP02SDTM":"2021-02-12 08:59:13","AP02EDTM":"2022-02-12 14:59:13","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":703,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-22","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2569,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.26459,"AVALU":"mg/L","BASE2":9.30935,"BASE":9.69398,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.04477,"PCHG2":-11.22276,"CHG":-1.4294,"PCHG":-14.74522,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-16 10:37:13","ADY":430,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-356","SUBJID":"id-356","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.24981,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 10:37:13","TRTEDTM":"2022-02-12 14:59:13","TRT01SDTM":"2020-03-12 10:37:13","TRT01EDTM":"2021-02-12 08:59:13","TRT02SDTM":"2021-02-12 08:59:13","TRT02EDTM":"2022-02-12 14:59:13","AP01SDTM":"2020-03-12 10:37:13","AP01EDTM":"2021-02-12 08:59:13","AP02SDTM":"2021-02-12 08:59:13","AP02EDTM":"2022-02-12 14:59:13","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":703,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-22","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4925,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.38533,"AVALU":"mg/L","BASE2":9.30935,"BASE":9.69398,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07598,"PCHG2":0.8162,"CHG":-0.30865,"PCHG":-3.18394,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-11 10:37:13","ADY":517,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-356","SUBJID":"id-356","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.24981,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 10:37:13","TRTEDTM":"2022-02-12 14:59:13","TRT01SDTM":"2020-03-12 10:37:13","TRT01EDTM":"2021-02-12 08:59:13","TRT02SDTM":"2021-02-12 08:59:13","TRT02EDTM":"2022-02-12 14:59:13","AP01SDTM":"2020-03-12 10:37:13","AP01EDTM":"2021-02-12 08:59:13","AP02SDTM":"2021-02-12 08:59:13","AP02EDTM":"2022-02-12 14:59:13","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":703,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-22","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2316,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.20944,"AVALU":"mg/L","BASE2":9.30935,"BASE":9.69398,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.09991,"PCHG2":-11.81509,"CHG":-1.48454,"PCHG":-15.31405,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-18 10:37:13","ADY":555,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-356","SUBJID":"id-356","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.24981,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 10:37:13","TRTEDTM":"2022-02-12 14:59:13","TRT01SDTM":"2020-03-12 10:37:13","TRT01EDTM":"2021-02-12 08:59:13","TRT02SDTM":"2021-02-12 08:59:13","TRT02EDTM":"2022-02-12 14:59:13","AP01SDTM":"2020-03-12 10:37:13","AP01EDTM":"2021-02-12 08:59:13","AP02SDTM":"2021-02-12 08:59:13","AP02EDTM":"2022-02-12 14:59:13","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":703,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-22","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7971,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.90208,"AVALU":"mg/L","BASE2":9.30935,"BASE":9.69398,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.40727,"PCHG2":-4.37486,"CHG":-0.7919,"PCHG":-8.16903,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-25 10:37:13","ADY":623,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-356","SUBJID":"id-356","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.24981,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 10:37:13","TRTEDTM":"2022-02-12 14:59:13","TRT01SDTM":"2020-03-12 10:37:13","TRT01EDTM":"2021-02-12 08:59:13","TRT02SDTM":"2021-02-12 08:59:13","TRT02EDTM":"2022-02-12 14:59:13","AP01SDTM":"2020-03-12 10:37:13","AP01EDTM":"2021-02-12 08:59:13","AP02SDTM":"2021-02-12 08:59:13","AP02EDTM":"2022-02-12 14:59:13","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":703,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-22","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7761,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8689,"AVALU":"g/L","BASE2":2.8689,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-08 10:37:13","ADY":88,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-356","SUBJID":"id-356","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.24981,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 10:37:13","TRTEDTM":"2022-02-12 14:59:13","TRT01SDTM":"2020-03-12 10:37:13","TRT01EDTM":"2021-02-12 08:59:13","TRT02SDTM":"2021-02-12 08:59:13","TRT02EDTM":"2022-02-12 14:59:13","AP01SDTM":"2020-03-12 10:37:13","AP01EDTM":"2021-02-12 08:59:13","AP02SDTM":"2021-02-12 08:59:13","AP02EDTM":"2022-02-12 14:59:13","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":703,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-22","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8217,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93612,"AVALU":"g/L","BASE2":2.8689,"BASE":2.93612,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.06722,"PCHG2":2.34313,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-08 10:37:13","ADY":149,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-356","SUBJID":"id-356","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.24981,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 10:37:13","TRTEDTM":"2022-02-12 14:59:13","TRT01SDTM":"2020-03-12 10:37:13","TRT01EDTM":"2021-02-12 08:59:13","TRT02SDTM":"2021-02-12 08:59:13","TRT02EDTM":"2022-02-12 14:59:13","AP01SDTM":"2020-03-12 10:37:13","AP01EDTM":"2021-02-12 08:59:13","AP02SDTM":"2021-02-12 08:59:13","AP02EDTM":"2022-02-12 14:59:13","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":703,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-22","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6481,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02112,"AVALU":"g/L","BASE2":2.8689,"BASE":2.93612,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15222,"PCHG2":5.30597,"CHG":0.085,"PCHG":2.895,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-12-31 10:37:13","ADY":294,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-356","SUBJID":"id-356","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.24981,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 10:37:13","TRTEDTM":"2022-02-12 14:59:13","TRT01SDTM":"2020-03-12 10:37:13","TRT01EDTM":"2021-02-12 08:59:13","TRT02SDTM":"2021-02-12 08:59:13","TRT02EDTM":"2022-02-12 14:59:13","AP01SDTM":"2020-03-12 10:37:13","AP01EDTM":"2021-02-12 08:59:13","AP02SDTM":"2021-02-12 08:59:13","AP02EDTM":"2022-02-12 14:59:13","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":703,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-22","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7131,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94617,"AVALU":"g/L","BASE2":2.8689,"BASE":2.93612,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07727,"PCHG2":2.69339,"CHG":0.01005,"PCHG":0.34224,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-16 10:37:13","ADY":430,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-356","SUBJID":"id-356","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.24981,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 10:37:13","TRTEDTM":"2022-02-12 14:59:13","TRT01SDTM":"2020-03-12 10:37:13","TRT01EDTM":"2021-02-12 08:59:13","TRT02SDTM":"2021-02-12 08:59:13","TRT02EDTM":"2022-02-12 14:59:13","AP01SDTM":"2020-03-12 10:37:13","AP01EDTM":"2021-02-12 08:59:13","AP02SDTM":"2021-02-12 08:59:13","AP02EDTM":"2022-02-12 14:59:13","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":703,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-22","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3224,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85341,"AVALU":"g/L","BASE2":2.8689,"BASE":2.93612,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01548,"PCHG2":-0.53968,"CHG":-0.08271,"PCHG":-2.81681,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-11 10:37:13","ADY":517,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-356","SUBJID":"id-356","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.24981,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 10:37:13","TRTEDTM":"2022-02-12 14:59:13","TRT01SDTM":"2020-03-12 10:37:13","TRT01EDTM":"2021-02-12 08:59:13","TRT02SDTM":"2021-02-12 08:59:13","TRT02EDTM":"2022-02-12 14:59:13","AP01SDTM":"2020-03-12 10:37:13","AP01EDTM":"2021-02-12 08:59:13","AP02SDTM":"2021-02-12 08:59:13","AP02EDTM":"2022-02-12 14:59:13","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":703,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-22","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3617,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74901,"AVALU":"g/L","BASE2":2.8689,"BASE":2.93612,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11988,"PCHG2":-4.17878,"CHG":-0.18711,"PCHG":-6.3726,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-18 10:37:13","ADY":555,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-356","SUBJID":"id-356","SITEID":"CHN-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.24981,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-08","TRTSDTM":"2020-03-12 10:37:13","TRTEDTM":"2022-02-12 14:59:13","TRT01SDTM":"2020-03-12 10:37:13","TRT01EDTM":"2021-02-12 08:59:13","TRT02SDTM":"2021-02-12 08:59:13","TRT02EDTM":"2022-02-12 14:59:13","AP01SDTM":"2020-03-12 10:37:13","AP01EDTM":"2021-02-12 08:59:13","AP02SDTM":"2021-02-12 08:59:13","AP02EDTM":"2022-02-12 14:59:13","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":703,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-22","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3819,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91492,"AVALU":"g/L","BASE2":2.8689,"BASE":2.93612,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04602,"PCHG2":1.6041,"CHG":-0.0212,"PCHG":-0.72211,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-25 10:37:13","ADY":623,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-358","SUBJID":"id-358","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.39002,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-28","TRTSDTM":"2020-12-02 13:47:17","TRTEDTM":"2023-12-03 07:47:17","TRT01SDTM":"2020-12-02 13:47:17","TRT01EDTM":"2022-12-03 01:47:17","TRT02SDTM":"2022-12-03 01:47:17","TRT02EDTM":"2023-12-03 07:47:17","AP01SDTM":"2020-12-02 13:47:17","AP01EDTM":"2022-12-03 01:47:17","AP02SDTM":"2022-12-03 01:47:17","AP02EDTM":"2023-12-03 07:47:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-03","EOSDY":1096,"LSTALVDT":"2023-12-18","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3769,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.92328,"AVALU":"U/L","BASE2":7.92328,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-15 13:47:17","ADY":103,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-358","SUBJID":"id-358","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.39002,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-28","TRTSDTM":"2020-12-02 13:47:17","TRTEDTM":"2023-12-03 07:47:17","TRT01SDTM":"2020-12-02 13:47:17","TRT01EDTM":"2022-12-03 01:47:17","TRT02SDTM":"2022-12-03 01:47:17","TRT02EDTM":"2023-12-03 07:47:17","AP01SDTM":"2020-12-02 13:47:17","AP01EDTM":"2022-12-03 01:47:17","AP02SDTM":"2022-12-03 01:47:17","AP02EDTM":"2023-12-03 07:47:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-03","EOSDY":1096,"LSTALVDT":"2023-12-18","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7807,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.37661,"AVALU":"U/L","BASE2":7.92328,"BASE":20.37661,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":12.45334,"PCHG2":157.17409,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-21 13:47:17","ADY":446,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-358","SUBJID":"id-358","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.39002,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-28","TRTSDTM":"2020-12-02 13:47:17","TRTEDTM":"2023-12-03 07:47:17","TRT01SDTM":"2020-12-02 13:47:17","TRT01EDTM":"2022-12-03 01:47:17","TRT02SDTM":"2022-12-03 01:47:17","TRT02EDTM":"2023-12-03 07:47:17","AP01SDTM":"2020-12-02 13:47:17","AP01EDTM":"2022-12-03 01:47:17","AP02SDTM":"2022-12-03 01:47:17","AP02EDTM":"2023-12-03 07:47:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-03","EOSDY":1096,"LSTALVDT":"2023-12-18","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8339,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.37342,"AVALU":"U/L","BASE2":7.92328,"BASE":20.37661,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":26.45014,"PCHG2":333.82829,"CHG":13.9968,"PCHG":68.69051,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-01 13:47:17","ADY":454,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-358","SUBJID":"id-358","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.39002,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-28","TRTSDTM":"2020-12-02 13:47:17","TRTEDTM":"2023-12-03 07:47:17","TRT01SDTM":"2020-12-02 13:47:17","TRT01EDTM":"2022-12-03 01:47:17","TRT02SDTM":"2022-12-03 01:47:17","TRT02EDTM":"2023-12-03 07:47:17","AP01SDTM":"2020-12-02 13:47:17","AP01EDTM":"2022-12-03 01:47:17","AP02SDTM":"2022-12-03 01:47:17","AP02EDTM":"2023-12-03 07:47:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-03","EOSDY":1096,"LSTALVDT":"2023-12-18","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2895,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.2887,"AVALU":"U/L","BASE2":7.92328,"BASE":20.37661,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.36542,"PCHG2":92.95928,"CHG":-5.08792,"PCHG":-24.96939,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-06 13:47:17","ADY":459,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-358","SUBJID":"id-358","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.39002,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-28","TRTSDTM":"2020-12-02 13:47:17","TRTEDTM":"2023-12-03 07:47:17","TRT01SDTM":"2020-12-02 13:47:17","TRT01EDTM":"2022-12-03 01:47:17","TRT02SDTM":"2022-12-03 01:47:17","TRT02EDTM":"2023-12-03 07:47:17","AP01SDTM":"2020-12-02 13:47:17","AP01EDTM":"2022-12-03 01:47:17","AP02SDTM":"2022-12-03 01:47:17","AP02EDTM":"2023-12-03 07:47:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-03","EOSDY":1096,"LSTALVDT":"2023-12-18","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4071,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.03298,"AVALU":"U/L","BASE2":7.92328,"BASE":20.37661,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.1097,"PCHG2":152.83703,"CHG":-0.34364,"PCHG":-1.68643,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-21 13:47:17","ADY":535,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-358","SUBJID":"id-358","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.39002,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-28","TRTSDTM":"2020-12-02 13:47:17","TRTEDTM":"2023-12-03 07:47:17","TRT01SDTM":"2020-12-02 13:47:17","TRT01EDTM":"2022-12-03 01:47:17","TRT02SDTM":"2022-12-03 01:47:17","TRT02EDTM":"2023-12-03 07:47:17","AP01SDTM":"2020-12-02 13:47:17","AP01EDTM":"2022-12-03 01:47:17","AP02SDTM":"2022-12-03 01:47:17","AP02EDTM":"2023-12-03 07:47:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-03","EOSDY":1096,"LSTALVDT":"2023-12-18","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6946,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.51845,"AVALU":"U/L","BASE2":7.92328,"BASE":20.37661,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.59517,"PCHG2":108.47999,"CHG":-3.85817,"PCHG":-18.93429,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-07 13:47:17","ADY":797,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-358","SUBJID":"id-358","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.39002,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-28","TRTSDTM":"2020-12-02 13:47:17","TRTEDTM":"2023-12-03 07:47:17","TRT01SDTM":"2020-12-02 13:47:17","TRT01EDTM":"2022-12-03 01:47:17","TRT02SDTM":"2022-12-03 01:47:17","TRT02EDTM":"2023-12-03 07:47:17","AP01SDTM":"2020-12-02 13:47:17","AP01EDTM":"2022-12-03 01:47:17","AP02SDTM":"2022-12-03 01:47:17","AP02EDTM":"2023-12-03 07:47:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-03","EOSDY":1096,"LSTALVDT":"2023-12-18","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2652,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.75981,"AVALU":"U/L","BASE2":7.92328,"BASE":20.37661,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.16346,"PCHG2":-39.9262,"CHG":-15.6168,"PCHG":-76.64081,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2023-05-09 13:47:17","ADY":888,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-358","SUBJID":"id-358","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.39002,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-28","TRTSDTM":"2020-12-02 13:47:17","TRTEDTM":"2023-12-03 07:47:17","TRT01SDTM":"2020-12-02 13:47:17","TRT01EDTM":"2022-12-03 01:47:17","TRT02SDTM":"2022-12-03 01:47:17","TRT02EDTM":"2023-12-03 07:47:17","AP01SDTM":"2020-12-02 13:47:17","AP01EDTM":"2022-12-03 01:47:17","AP02SDTM":"2022-12-03 01:47:17","AP02EDTM":"2023-12-03 07:47:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-03","EOSDY":1096,"LSTALVDT":"2023-12-18","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8329,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.33837,"AVALU":"mg/L","BASE2":10.33837,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-03-15 13:47:17","ADY":103,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-358","SUBJID":"id-358","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.39002,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-28","TRTSDTM":"2020-12-02 13:47:17","TRTEDTM":"2023-12-03 07:47:17","TRT01SDTM":"2020-12-02 13:47:17","TRT01EDTM":"2022-12-03 01:47:17","TRT02SDTM":"2022-12-03 01:47:17","TRT02EDTM":"2023-12-03 07:47:17","AP01SDTM":"2020-12-02 13:47:17","AP01EDTM":"2022-12-03 01:47:17","AP02SDTM":"2022-12-03 01:47:17","AP02EDTM":"2023-12-03 07:47:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-03","EOSDY":1096,"LSTALVDT":"2023-12-18","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":869,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.23144,"AVALU":"mg/L","BASE2":10.33837,"BASE":8.23144,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.10693,"PCHG2":-20.3797,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-21 13:47:17","ADY":446,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-358","SUBJID":"id-358","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.39002,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-28","TRTSDTM":"2020-12-02 13:47:17","TRTEDTM":"2023-12-03 07:47:17","TRT01SDTM":"2020-12-02 13:47:17","TRT01EDTM":"2022-12-03 01:47:17","TRT02SDTM":"2022-12-03 01:47:17","TRT02EDTM":"2023-12-03 07:47:17","AP01SDTM":"2020-12-02 13:47:17","AP01EDTM":"2022-12-03 01:47:17","AP02SDTM":"2022-12-03 01:47:17","AP02EDTM":"2023-12-03 07:47:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-03","EOSDY":1096,"LSTALVDT":"2023-12-18","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8067,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.48802,"AVALU":"mg/L","BASE2":10.33837,"BASE":8.23144,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14964,"PCHG2":1.44744,"CHG":2.25657,"PCHG":27.41405,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-03-01 13:47:17","ADY":454,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-358","SUBJID":"id-358","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.39002,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-28","TRTSDTM":"2020-12-02 13:47:17","TRTEDTM":"2023-12-03 07:47:17","TRT01SDTM":"2020-12-02 13:47:17","TRT01EDTM":"2022-12-03 01:47:17","TRT02SDTM":"2022-12-03 01:47:17","TRT02EDTM":"2023-12-03 07:47:17","AP01SDTM":"2020-12-02 13:47:17","AP01EDTM":"2022-12-03 01:47:17","AP02SDTM":"2022-12-03 01:47:17","AP02EDTM":"2023-12-03 07:47:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-03","EOSDY":1096,"LSTALVDT":"2023-12-18","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6513,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.62754,"AVALU":"mg/L","BASE2":10.33837,"BASE":8.23144,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.71083,"PCHG2":-26.22105,"CHG":-0.6039,"PCHG":-7.3365,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2022-03-06 13:47:17","ADY":459,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-358","SUBJID":"id-358","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.39002,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-28","TRTSDTM":"2020-12-02 13:47:17","TRTEDTM":"2023-12-03 07:47:17","TRT01SDTM":"2020-12-02 13:47:17","TRT01EDTM":"2022-12-03 01:47:17","TRT02SDTM":"2022-12-03 01:47:17","TRT02EDTM":"2023-12-03 07:47:17","AP01SDTM":"2020-12-02 13:47:17","AP01EDTM":"2022-12-03 01:47:17","AP02SDTM":"2022-12-03 01:47:17","AP02EDTM":"2023-12-03 07:47:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-03","EOSDY":1096,"LSTALVDT":"2023-12-18","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1806,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.88847,"AVALU":"mg/L","BASE2":10.33837,"BASE":8.23144,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.44991,"PCHG2":-33.36993,"CHG":-1.34298,"PCHG":-16.31522,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-05-21 13:47:17","ADY":535,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-358","SUBJID":"id-358","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.39002,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-28","TRTSDTM":"2020-12-02 13:47:17","TRTEDTM":"2023-12-03 07:47:17","TRT01SDTM":"2020-12-02 13:47:17","TRT01EDTM":"2022-12-03 01:47:17","TRT02SDTM":"2022-12-03 01:47:17","TRT02EDTM":"2023-12-03 07:47:17","AP01SDTM":"2020-12-02 13:47:17","AP01EDTM":"2022-12-03 01:47:17","AP02SDTM":"2022-12-03 01:47:17","AP02EDTM":"2023-12-03 07:47:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-03","EOSDY":1096,"LSTALVDT":"2023-12-18","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":525,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.70108,"AVALU":"mg/L","BASE2":10.33837,"BASE":8.23144,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.6373,"PCHG2":-6.16439,"CHG":1.46963,"PCHG":17.85389,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-07 13:47:17","ADY":797,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-358","SUBJID":"id-358","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.39002,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-28","TRTSDTM":"2020-12-02 13:47:17","TRTEDTM":"2023-12-03 07:47:17","TRT01SDTM":"2020-12-02 13:47:17","TRT01EDTM":"2022-12-03 01:47:17","TRT02SDTM":"2022-12-03 01:47:17","TRT02EDTM":"2023-12-03 07:47:17","AP01SDTM":"2020-12-02 13:47:17","AP01EDTM":"2022-12-03 01:47:17","AP02SDTM":"2022-12-03 01:47:17","AP02EDTM":"2023-12-03 07:47:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-03","EOSDY":1096,"LSTALVDT":"2023-12-18","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4550,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.07208,"AVALU":"mg/L","BASE2":10.33837,"BASE":8.23144,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.7337,"PCHG2":7.09687,"CHG":2.84063,"PCHG":34.50951,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2023-05-09 13:47:17","ADY":888,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-358","SUBJID":"id-358","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.39002,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-28","TRTSDTM":"2020-12-02 13:47:17","TRTEDTM":"2023-12-03 07:47:17","TRT01SDTM":"2020-12-02 13:47:17","TRT01EDTM":"2022-12-03 01:47:17","TRT02SDTM":"2022-12-03 01:47:17","TRT02EDTM":"2023-12-03 07:47:17","AP01SDTM":"2020-12-02 13:47:17","AP01EDTM":"2022-12-03 01:47:17","AP02SDTM":"2022-12-03 01:47:17","AP02EDTM":"2023-12-03 07:47:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-03","EOSDY":1096,"LSTALVDT":"2023-12-18","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7204,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94096,"AVALU":"g/L","BASE2":2.94096,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-15 13:47:17","ADY":103,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-358","SUBJID":"id-358","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.39002,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-28","TRTSDTM":"2020-12-02 13:47:17","TRTEDTM":"2023-12-03 07:47:17","TRT01SDTM":"2020-12-02 13:47:17","TRT01EDTM":"2022-12-03 01:47:17","TRT02SDTM":"2022-12-03 01:47:17","TRT02EDTM":"2023-12-03 07:47:17","AP01SDTM":"2020-12-02 13:47:17","AP01EDTM":"2022-12-03 01:47:17","AP02SDTM":"2022-12-03 01:47:17","AP02EDTM":"2023-12-03 07:47:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-03","EOSDY":1096,"LSTALVDT":"2023-12-18","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2969,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86465,"AVALU":"g/L","BASE2":2.94096,"BASE":2.86465,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.07631,"PCHG2":-2.59487,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-21 13:47:17","ADY":446,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-358","SUBJID":"id-358","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.39002,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-28","TRTSDTM":"2020-12-02 13:47:17","TRTEDTM":"2023-12-03 07:47:17","TRT01SDTM":"2020-12-02 13:47:17","TRT01EDTM":"2022-12-03 01:47:17","TRT02SDTM":"2022-12-03 01:47:17","TRT02EDTM":"2023-12-03 07:47:17","AP01SDTM":"2020-12-02 13:47:17","AP01EDTM":"2022-12-03 01:47:17","AP02SDTM":"2022-12-03 01:47:17","AP02EDTM":"2023-12-03 07:47:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-03","EOSDY":1096,"LSTALVDT":"2023-12-18","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3736,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79579,"AVALU":"g/L","BASE2":2.94096,"BASE":2.86465,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14517,"PCHG2":-4.93621,"CHG":-0.06886,"PCHG":-2.40372,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-01 13:47:17","ADY":454,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-358","SUBJID":"id-358","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.39002,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-28","TRTSDTM":"2020-12-02 13:47:17","TRTEDTM":"2023-12-03 07:47:17","TRT01SDTM":"2020-12-02 13:47:17","TRT01EDTM":"2022-12-03 01:47:17","TRT02SDTM":"2022-12-03 01:47:17","TRT02EDTM":"2023-12-03 07:47:17","AP01SDTM":"2020-12-02 13:47:17","AP01EDTM":"2022-12-03 01:47:17","AP02SDTM":"2022-12-03 01:47:17","AP02EDTM":"2023-12-03 07:47:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-03","EOSDY":1096,"LSTALVDT":"2023-12-18","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":995,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95022,"AVALU":"g/L","BASE2":2.94096,"BASE":2.86465,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00925,"PCHG2":0.31469,"CHG":0.08557,"PCHG":2.98706,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-06 13:47:17","ADY":459,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-358","SUBJID":"id-358","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.39002,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-28","TRTSDTM":"2020-12-02 13:47:17","TRTEDTM":"2023-12-03 07:47:17","TRT01SDTM":"2020-12-02 13:47:17","TRT01EDTM":"2022-12-03 01:47:17","TRT02SDTM":"2022-12-03 01:47:17","TRT02EDTM":"2023-12-03 07:47:17","AP01SDTM":"2020-12-02 13:47:17","AP01EDTM":"2022-12-03 01:47:17","AP02SDTM":"2022-12-03 01:47:17","AP02EDTM":"2023-12-03 07:47:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-03","EOSDY":1096,"LSTALVDT":"2023-12-18","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8103,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92254,"AVALU":"g/L","BASE2":2.94096,"BASE":2.86465,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01843,"PCHG2":-0.62655,"CHG":0.05789,"PCHG":2.02075,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-21 13:47:17","ADY":535,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-358","SUBJID":"id-358","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.39002,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-28","TRTSDTM":"2020-12-02 13:47:17","TRTEDTM":"2023-12-03 07:47:17","TRT01SDTM":"2020-12-02 13:47:17","TRT01EDTM":"2022-12-03 01:47:17","TRT02SDTM":"2022-12-03 01:47:17","TRT02EDTM":"2023-12-03 07:47:17","AP01SDTM":"2020-12-02 13:47:17","AP01EDTM":"2022-12-03 01:47:17","AP02SDTM":"2022-12-03 01:47:17","AP02EDTM":"2023-12-03 07:47:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-03","EOSDY":1096,"LSTALVDT":"2023-12-18","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1115,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98951,"AVALU":"g/L","BASE2":2.94096,"BASE":2.86465,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04855,"PCHG2":1.65067,"CHG":0.12486,"PCHG":4.35864,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-07 13:47:17","ADY":797,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-358","SUBJID":"id-358","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.39002,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-28","TRTSDTM":"2020-12-02 13:47:17","TRTEDTM":"2023-12-03 07:47:17","TRT01SDTM":"2020-12-02 13:47:17","TRT01EDTM":"2022-12-03 01:47:17","TRT02SDTM":"2022-12-03 01:47:17","TRT02EDTM":"2023-12-03 07:47:17","AP01SDTM":"2020-12-02 13:47:17","AP01EDTM":"2022-12-03 01:47:17","AP02SDTM":"2022-12-03 01:47:17","AP02EDTM":"2023-12-03 07:47:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-03","EOSDY":1096,"LSTALVDT":"2023-12-18","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8370,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95117,"AVALU":"g/L","BASE2":2.94096,"BASE":2.86465,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0102,"PCHG2":0.34697,"CHG":0.08652,"PCHG":3.02021,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-09 13:47:17","ADY":888,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-362","SUBJID":"id-362","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.60836,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-23","TRTSDTM":"2020-04-23 03:00:32","TRTEDTM":"2023-04-23 21:00:32","TRT01SDTM":"2020-04-23 03:00:32","TRT01EDTM":"2022-04-23 15:00:32","TRT02SDTM":"2022-04-23 15:00:32","TRT02EDTM":"2023-04-23 21:00:32","AP01SDTM":"2020-04-23 03:00:32","AP01EDTM":"2022-04-23 15:00:32","AP02SDTM":"2022-04-23 15:00:32","AP02EDTM":"2023-04-23 21:00:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-23","EOSDY":1096,"LSTALVDT":"2023-05-10","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3324,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.2348,"AVALU":"U/L","BASE2":20.2348,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-15 03:00:32","ADY":206,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-362","SUBJID":"id-362","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.60836,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-23","TRTSDTM":"2020-04-23 03:00:32","TRTEDTM":"2023-04-23 21:00:32","TRT01SDTM":"2020-04-23 03:00:32","TRT01EDTM":"2022-04-23 15:00:32","TRT02SDTM":"2022-04-23 15:00:32","TRT02EDTM":"2023-04-23 21:00:32","AP01SDTM":"2020-04-23 03:00:32","AP01EDTM":"2022-04-23 15:00:32","AP02SDTM":"2022-04-23 15:00:32","AP02EDTM":"2023-04-23 21:00:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-23","EOSDY":1096,"LSTALVDT":"2023-05-10","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5356,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.7007,"AVALU":"U/L","BASE2":20.2348,"BASE":14.7007,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-5.53411,"PCHG2":-27.34946,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-05 03:00:32","ADY":257,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-362","SUBJID":"id-362","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.60836,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-23","TRTSDTM":"2020-04-23 03:00:32","TRTEDTM":"2023-04-23 21:00:32","TRT01SDTM":"2020-04-23 03:00:32","TRT01EDTM":"2022-04-23 15:00:32","TRT02SDTM":"2022-04-23 15:00:32","TRT02EDTM":"2023-04-23 21:00:32","AP01SDTM":"2020-04-23 03:00:32","AP01EDTM":"2022-04-23 15:00:32","AP02SDTM":"2022-04-23 15:00:32","AP02EDTM":"2023-04-23 21:00:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-23","EOSDY":1096,"LSTALVDT":"2023-05-10","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5193,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.85997,"AVALU":"U/L","BASE2":20.2348,"BASE":14.7007,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.62517,"PCHG2":22.85749,"CHG":10.15928,"PCHG":69.10747,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-29 03:00:32","ADY":432,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-362","SUBJID":"id-362","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.60836,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-23","TRTSDTM":"2020-04-23 03:00:32","TRTEDTM":"2023-04-23 21:00:32","TRT01SDTM":"2020-04-23 03:00:32","TRT01EDTM":"2022-04-23 15:00:32","TRT02SDTM":"2022-04-23 15:00:32","TRT02EDTM":"2023-04-23 21:00:32","AP01SDTM":"2020-04-23 03:00:32","AP01EDTM":"2022-04-23 15:00:32","AP02SDTM":"2022-04-23 15:00:32","AP02EDTM":"2023-04-23 21:00:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-23","EOSDY":1096,"LSTALVDT":"2023-05-10","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1306,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.20175,"AVALU":"U/L","BASE2":20.2348,"BASE":14.7007,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.96694,"PCHG2":34.43048,"CHG":12.50105,"PCHG":85.03714,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-03 03:00:32","ADY":528,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-362","SUBJID":"id-362","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.60836,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-23","TRTSDTM":"2020-04-23 03:00:32","TRTEDTM":"2023-04-23 21:00:32","TRT01SDTM":"2020-04-23 03:00:32","TRT01EDTM":"2022-04-23 15:00:32","TRT02SDTM":"2022-04-23 15:00:32","TRT02EDTM":"2023-04-23 21:00:32","AP01SDTM":"2020-04-23 03:00:32","AP01EDTM":"2022-04-23 15:00:32","AP02SDTM":"2022-04-23 15:00:32","AP02EDTM":"2023-04-23 21:00:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-23","EOSDY":1096,"LSTALVDT":"2023-05-10","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6021,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.43493,"AVALU":"U/L","BASE2":20.2348,"BASE":14.7007,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.79987,"PCHG2":-83.02462,"CHG":-11.26576,"PCHG":-76.63421,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-12-24 03:00:32","ADY":610,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-362","SUBJID":"id-362","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.60836,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-23","TRTSDTM":"2020-04-23 03:00:32","TRTEDTM":"2023-04-23 21:00:32","TRT01SDTM":"2020-04-23 03:00:32","TRT01EDTM":"2022-04-23 15:00:32","TRT02SDTM":"2022-04-23 15:00:32","TRT02EDTM":"2023-04-23 21:00:32","AP01SDTM":"2020-04-23 03:00:32","AP01EDTM":"2022-04-23 15:00:32","AP02SDTM":"2022-04-23 15:00:32","AP02EDTM":"2023-04-23 21:00:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-23","EOSDY":1096,"LSTALVDT":"2023-05-10","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6813,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.73591,"AVALU":"U/L","BASE2":20.2348,"BASE":14.7007,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.49889,"PCHG2":-42.00137,"CHG":-2.96479,"PCHG":-20.16765,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-25 03:00:32","ADY":701,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-362","SUBJID":"id-362","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.60836,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-23","TRTSDTM":"2020-04-23 03:00:32","TRTEDTM":"2023-04-23 21:00:32","TRT01SDTM":"2020-04-23 03:00:32","TRT01EDTM":"2022-04-23 15:00:32","TRT02SDTM":"2022-04-23 15:00:32","TRT02EDTM":"2023-04-23 21:00:32","AP01SDTM":"2020-04-23 03:00:32","AP01EDTM":"2022-04-23 15:00:32","AP02SDTM":"2022-04-23 15:00:32","AP02EDTM":"2023-04-23 21:00:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-23","EOSDY":1096,"LSTALVDT":"2023-05-10","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2049,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.71891,"AVALU":"U/L","BASE2":20.2348,"BASE":14.7007,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.51589,"PCHG2":-32.20141,"CHG":-0.98178,"PCHG":-6.67848,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-20 03:00:32","ADY":849,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-362","SUBJID":"id-362","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.60836,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-23","TRTSDTM":"2020-04-23 03:00:32","TRTEDTM":"2023-04-23 21:00:32","TRT01SDTM":"2020-04-23 03:00:32","TRT01EDTM":"2022-04-23 15:00:32","TRT02SDTM":"2022-04-23 15:00:32","TRT02EDTM":"2023-04-23 21:00:32","AP01SDTM":"2020-04-23 03:00:32","AP01EDTM":"2022-04-23 15:00:32","AP02SDTM":"2022-04-23 15:00:32","AP02EDTM":"2023-04-23 21:00:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-23","EOSDY":1096,"LSTALVDT":"2023-05-10","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7176,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.19405,"AVALU":"mg/L","BASE2":8.19405,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-15 03:00:32","ADY":206,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-362","SUBJID":"id-362","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.60836,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-23","TRTSDTM":"2020-04-23 03:00:32","TRTEDTM":"2023-04-23 21:00:32","TRT01SDTM":"2020-04-23 03:00:32","TRT01EDTM":"2022-04-23 15:00:32","TRT02SDTM":"2022-04-23 15:00:32","TRT02EDTM":"2023-04-23 21:00:32","AP01SDTM":"2020-04-23 03:00:32","AP01EDTM":"2022-04-23 15:00:32","AP02SDTM":"2022-04-23 15:00:32","AP02EDTM":"2023-04-23 21:00:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-23","EOSDY":1096,"LSTALVDT":"2023-05-10","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":444,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.11676,"AVALU":"mg/L","BASE2":8.19405,"BASE":9.11676,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.92271,"PCHG2":11.26075,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-05 03:00:32","ADY":257,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-362","SUBJID":"id-362","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.60836,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-23","TRTSDTM":"2020-04-23 03:00:32","TRTEDTM":"2023-04-23 21:00:32","TRT01SDTM":"2020-04-23 03:00:32","TRT01EDTM":"2022-04-23 15:00:32","TRT02SDTM":"2022-04-23 15:00:32","TRT02EDTM":"2023-04-23 21:00:32","AP01SDTM":"2020-04-23 03:00:32","AP01EDTM":"2022-04-23 15:00:32","AP02SDTM":"2022-04-23 15:00:32","AP02EDTM":"2023-04-23 21:00:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-23","EOSDY":1096,"LSTALVDT":"2023-05-10","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7683,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.79776,"AVALU":"mg/L","BASE2":8.19405,"BASE":9.11676,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.60371,"PCHG2":7.36767,"CHG":-0.319,"PCHG":-3.49906,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-29 03:00:32","ADY":432,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-362","SUBJID":"id-362","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.60836,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-23","TRTSDTM":"2020-04-23 03:00:32","TRTEDTM":"2023-04-23 21:00:32","TRT01SDTM":"2020-04-23 03:00:32","TRT01EDTM":"2022-04-23 15:00:32","TRT02SDTM":"2022-04-23 15:00:32","TRT02EDTM":"2023-04-23 21:00:32","AP01SDTM":"2020-04-23 03:00:32","AP01EDTM":"2022-04-23 15:00:32","AP02SDTM":"2022-04-23 15:00:32","AP02EDTM":"2023-04-23 21:00:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-23","EOSDY":1096,"LSTALVDT":"2023-05-10","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1036,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.7815,"AVALU":"mg/L","BASE2":8.19405,"BASE":9.11676,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.41255,"PCHG2":-5.03477,"CHG":-1.33526,"PCHG":-14.64624,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-10-03 03:00:32","ADY":528,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-362","SUBJID":"id-362","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.60836,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-23","TRTSDTM":"2020-04-23 03:00:32","TRTEDTM":"2023-04-23 21:00:32","TRT01SDTM":"2020-04-23 03:00:32","TRT01EDTM":"2022-04-23 15:00:32","TRT02SDTM":"2022-04-23 15:00:32","TRT02EDTM":"2023-04-23 21:00:32","AP01SDTM":"2020-04-23 03:00:32","AP01EDTM":"2022-04-23 15:00:32","AP02SDTM":"2022-04-23 15:00:32","AP02EDTM":"2023-04-23 21:00:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-23","EOSDY":1096,"LSTALVDT":"2023-05-10","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7513,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.36505,"AVALU":"mg/L","BASE2":8.19405,"BASE":9.11676,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.82899,"PCHG2":-10.11703,"CHG":-1.75171,"PCHG":-19.21412,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-12-24 03:00:32","ADY":610,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-362","SUBJID":"id-362","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.60836,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-23","TRTSDTM":"2020-04-23 03:00:32","TRTEDTM":"2023-04-23 21:00:32","TRT01SDTM":"2020-04-23 03:00:32","TRT01EDTM":"2022-04-23 15:00:32","TRT02SDTM":"2022-04-23 15:00:32","TRT02EDTM":"2023-04-23 21:00:32","AP01SDTM":"2020-04-23 03:00:32","AP01EDTM":"2022-04-23 15:00:32","AP02SDTM":"2022-04-23 15:00:32","AP02EDTM":"2023-04-23 21:00:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-23","EOSDY":1096,"LSTALVDT":"2023-05-10","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":682,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.52434,"AVALU":"mg/L","BASE2":8.19405,"BASE":9.11676,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.33029,"PCHG2":16.23487,"CHG":0.40758,"PCHG":4.47068,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-25 03:00:32","ADY":701,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-362","SUBJID":"id-362","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.60836,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-23","TRTSDTM":"2020-04-23 03:00:32","TRTEDTM":"2023-04-23 21:00:32","TRT01SDTM":"2020-04-23 03:00:32","TRT01EDTM":"2022-04-23 15:00:32","TRT02SDTM":"2022-04-23 15:00:32","TRT02EDTM":"2023-04-23 21:00:32","AP01SDTM":"2020-04-23 03:00:32","AP01EDTM":"2022-04-23 15:00:32","AP02SDTM":"2022-04-23 15:00:32","AP02EDTM":"2023-04-23 21:00:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-23","EOSDY":1096,"LSTALVDT":"2023-05-10","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1362,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.90561,"AVALU":"mg/L","BASE2":8.19405,"BASE":9.11676,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.28844,"PCHG2":-3.52013,"CHG":-1.21115,"PCHG":-13.2849,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-08-20 03:00:32","ADY":849,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-362","SUBJID":"id-362","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.60836,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-23","TRTSDTM":"2020-04-23 03:00:32","TRTEDTM":"2023-04-23 21:00:32","TRT01SDTM":"2020-04-23 03:00:32","TRT01EDTM":"2022-04-23 15:00:32","TRT02SDTM":"2022-04-23 15:00:32","TRT02EDTM":"2023-04-23 21:00:32","AP01SDTM":"2020-04-23 03:00:32","AP01EDTM":"2022-04-23 15:00:32","AP02SDTM":"2022-04-23 15:00:32","AP02EDTM":"2023-04-23 21:00:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-23","EOSDY":1096,"LSTALVDT":"2023-05-10","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4866,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84086,"AVALU":"g/L","BASE2":2.84086,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-15 03:00:32","ADY":206,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-362","SUBJID":"id-362","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.60836,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-23","TRTSDTM":"2020-04-23 03:00:32","TRTEDTM":"2023-04-23 21:00:32","TRT01SDTM":"2020-04-23 03:00:32","TRT01EDTM":"2022-04-23 15:00:32","TRT02SDTM":"2022-04-23 15:00:32","TRT02EDTM":"2023-04-23 21:00:32","AP01SDTM":"2020-04-23 03:00:32","AP01EDTM":"2022-04-23 15:00:32","AP02SDTM":"2022-04-23 15:00:32","AP02EDTM":"2023-04-23 21:00:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-23","EOSDY":1096,"LSTALVDT":"2023-05-10","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7913,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91193,"AVALU":"g/L","BASE2":2.84086,"BASE":2.91193,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.07107,"PCHG2":2.50173,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-05 03:00:32","ADY":257,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-362","SUBJID":"id-362","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.60836,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-23","TRTSDTM":"2020-04-23 03:00:32","TRTEDTM":"2023-04-23 21:00:32","TRT01SDTM":"2020-04-23 03:00:32","TRT01EDTM":"2022-04-23 15:00:32","TRT02SDTM":"2022-04-23 15:00:32","TRT02EDTM":"2023-04-23 21:00:32","AP01SDTM":"2020-04-23 03:00:32","AP01EDTM":"2022-04-23 15:00:32","AP02SDTM":"2022-04-23 15:00:32","AP02EDTM":"2023-04-23 21:00:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-23","EOSDY":1096,"LSTALVDT":"2023-05-10","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6787,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78485,"AVALU":"g/L","BASE2":2.84086,"BASE":2.91193,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05601,"PCHG2":-1.97144,"CHG":-0.12708,"PCHG":-4.36399,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-29 03:00:32","ADY":432,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-362","SUBJID":"id-362","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.60836,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-23","TRTSDTM":"2020-04-23 03:00:32","TRTEDTM":"2023-04-23 21:00:32","TRT01SDTM":"2020-04-23 03:00:32","TRT01EDTM":"2022-04-23 15:00:32","TRT02SDTM":"2022-04-23 15:00:32","TRT02EDTM":"2023-04-23 21:00:32","AP01SDTM":"2020-04-23 03:00:32","AP01EDTM":"2022-04-23 15:00:32","AP02SDTM":"2022-04-23 15:00:32","AP02EDTM":"2023-04-23 21:00:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-23","EOSDY":1096,"LSTALVDT":"2023-05-10","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5277,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87437,"AVALU":"g/L","BASE2":2.84086,"BASE":2.91193,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03351,"PCHG2":1.17952,"CHG":-0.03756,"PCHG":-1.28994,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-03 03:00:32","ADY":528,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-362","SUBJID":"id-362","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.60836,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-23","TRTSDTM":"2020-04-23 03:00:32","TRTEDTM":"2023-04-23 21:00:32","TRT01SDTM":"2020-04-23 03:00:32","TRT01EDTM":"2022-04-23 15:00:32","TRT02SDTM":"2022-04-23 15:00:32","TRT02EDTM":"2023-04-23 21:00:32","AP01SDTM":"2020-04-23 03:00:32","AP01EDTM":"2022-04-23 15:00:32","AP02SDTM":"2022-04-23 15:00:32","AP02EDTM":"2023-04-23 21:00:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-23","EOSDY":1096,"LSTALVDT":"2023-05-10","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4521,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95301,"AVALU":"g/L","BASE2":2.84086,"BASE":2.91193,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11216,"PCHG2":3.94796,"CHG":0.04109,"PCHG":1.41094,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-24 03:00:32","ADY":610,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-362","SUBJID":"id-362","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.60836,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-23","TRTSDTM":"2020-04-23 03:00:32","TRTEDTM":"2023-04-23 21:00:32","TRT01SDTM":"2020-04-23 03:00:32","TRT01EDTM":"2022-04-23 15:00:32","TRT02SDTM":"2022-04-23 15:00:32","TRT02EDTM":"2023-04-23 21:00:32","AP01SDTM":"2020-04-23 03:00:32","AP01EDTM":"2022-04-23 15:00:32","AP02SDTM":"2022-04-23 15:00:32","AP02EDTM":"2023-04-23 21:00:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-23","EOSDY":1096,"LSTALVDT":"2023-05-10","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1195,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89025,"AVALU":"g/L","BASE2":2.84086,"BASE":2.91193,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04939,"PCHG2":1.73865,"CHG":-0.02168,"PCHG":-0.74445,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-25 03:00:32","ADY":701,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-362","SUBJID":"id-362","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.60836,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-23","TRTSDTM":"2020-04-23 03:00:32","TRTEDTM":"2023-04-23 21:00:32","TRT01SDTM":"2020-04-23 03:00:32","TRT01EDTM":"2022-04-23 15:00:32","TRT02SDTM":"2022-04-23 15:00:32","TRT02EDTM":"2023-04-23 21:00:32","AP01SDTM":"2020-04-23 03:00:32","AP01EDTM":"2022-04-23 15:00:32","AP02SDTM":"2022-04-23 15:00:32","AP02EDTM":"2023-04-23 21:00:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-23","EOSDY":1096,"LSTALVDT":"2023-05-10","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5440,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01642,"AVALU":"g/L","BASE2":2.84086,"BASE":2.91193,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17556,"PCHG2":6.17997,"CHG":0.10449,"PCHG":3.58847,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-08-20 03:00:32","ADY":849,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-364","SUBJID":"id-364","SITEID":"CHN-11","AGE":48,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.68839,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-20 05:32:09","TRTEDTM":"2023-12-20 23:32:09","TRT01SDTM":"2020-12-20 05:32:09","TRT01EDTM":"2022-12-20 17:32:09","TRT02SDTM":"2022-12-20 17:32:09","TRT02EDTM":"2023-12-20 23:32:09","AP01SDTM":"2020-12-20 05:32:09","AP01EDTM":"2022-12-20 17:32:09","AP02SDTM":"2022-12-20 17:32:09","AP02EDTM":"2023-12-20 23:32:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8020,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.27457,"AVALU":"U/L","BASE2":12.27457,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-23 05:32:09","ADY":154,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-364","SUBJID":"id-364","SITEID":"CHN-11","AGE":48,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.68839,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-20 05:32:09","TRTEDTM":"2023-12-20 23:32:09","TRT01SDTM":"2020-12-20 05:32:09","TRT01EDTM":"2022-12-20 17:32:09","TRT02SDTM":"2022-12-20 17:32:09","TRT02EDTM":"2023-12-20 23:32:09","AP01SDTM":"2020-12-20 05:32:09","AP01EDTM":"2022-12-20 17:32:09","AP02SDTM":"2022-12-20 17:32:09","AP02EDTM":"2023-12-20 23:32:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3034,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.50169,"AVALU":"U/L","BASE2":12.27457,"BASE":28.50169,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":16.22711,"PCHG2":132.20104,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-24 05:32:09","ADY":186,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-364","SUBJID":"id-364","SITEID":"CHN-11","AGE":48,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.68839,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-20 05:32:09","TRTEDTM":"2023-12-20 23:32:09","TRT01SDTM":"2020-12-20 05:32:09","TRT01EDTM":"2022-12-20 17:32:09","TRT02SDTM":"2022-12-20 17:32:09","TRT02EDTM":"2023-12-20 23:32:09","AP01SDTM":"2020-12-20 05:32:09","AP01EDTM":"2022-12-20 17:32:09","AP02SDTM":"2022-12-20 17:32:09","AP02EDTM":"2023-12-20 23:32:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6209,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.43103,"AVALU":"U/L","BASE2":12.27457,"BASE":28.50169,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.15646,"PCHG2":25.7154,"CHG":-13.07066,"PCHG":-45.85924,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-04 05:32:09","ADY":258,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-364","SUBJID":"id-364","SITEID":"CHN-11","AGE":48,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.68839,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-20 05:32:09","TRTEDTM":"2023-12-20 23:32:09","TRT01SDTM":"2020-12-20 05:32:09","TRT01EDTM":"2022-12-20 17:32:09","TRT02SDTM":"2022-12-20 17:32:09","TRT02EDTM":"2023-12-20 23:32:09","AP01SDTM":"2020-12-20 05:32:09","AP01EDTM":"2022-12-20 17:32:09","AP02SDTM":"2022-12-20 17:32:09","AP02EDTM":"2023-12-20 23:32:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":911,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.63478,"AVALU":"U/L","BASE2":12.27457,"BASE":28.50169,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.3602,"PCHG2":125.13839,"CHG":-0.86691,"PCHG":-3.04161,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-20 05:32:09","ADY":455,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-364","SUBJID":"id-364","SITEID":"CHN-11","AGE":48,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.68839,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-20 05:32:09","TRTEDTM":"2023-12-20 23:32:09","TRT01SDTM":"2020-12-20 05:32:09","TRT01EDTM":"2022-12-20 17:32:09","TRT02SDTM":"2022-12-20 17:32:09","TRT02EDTM":"2023-12-20 23:32:09","AP01SDTM":"2020-12-20 05:32:09","AP01EDTM":"2022-12-20 17:32:09","AP02SDTM":"2022-12-20 17:32:09","AP02EDTM":"2023-12-20 23:32:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8059,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.51038,"AVALU":"U/L","BASE2":12.27457,"BASE":28.50169,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.23581,"PCHG2":91.53727,"CHG":-4.9913,"PCHG":-17.51231,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-12 05:32:09","ADY":661,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-364","SUBJID":"id-364","SITEID":"CHN-11","AGE":48,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.68839,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-20 05:32:09","TRTEDTM":"2023-12-20 23:32:09","TRT01SDTM":"2020-12-20 05:32:09","TRT01EDTM":"2022-12-20 17:32:09","TRT02SDTM":"2022-12-20 17:32:09","TRT02EDTM":"2023-12-20 23:32:09","AP01SDTM":"2020-12-20 05:32:09","AP01EDTM":"2022-12-20 17:32:09","AP02SDTM":"2022-12-20 17:32:09","AP02EDTM":"2023-12-20 23:32:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6155,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.29852,"AVALU":"U/L","BASE2":12.27457,"BASE":28.50169,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02394,"PCHG2":0.19505,"CHG":-16.20317,"PCHG":-56.84987,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-11 05:32:09","ADY":721,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-364","SUBJID":"id-364","SITEID":"CHN-11","AGE":48,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.68839,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-20 05:32:09","TRTEDTM":"2023-12-20 23:32:09","TRT01SDTM":"2020-12-20 05:32:09","TRT01EDTM":"2022-12-20 17:32:09","TRT02SDTM":"2022-12-20 17:32:09","TRT02EDTM":"2023-12-20 23:32:09","AP01SDTM":"2020-12-20 05:32:09","AP01EDTM":"2022-12-20 17:32:09","AP02SDTM":"2022-12-20 17:32:09","AP02EDTM":"2023-12-20 23:32:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2184,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.66695,"AVALU":"U/L","BASE2":12.27457,"BASE":28.50169,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.39237,"PCHG2":149.84124,"CHG":2.16526,"PCHG":7.59695,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-26 05:32:09","ADY":948,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-364","SUBJID":"id-364","SITEID":"CHN-11","AGE":48,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.68839,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-20 05:32:09","TRTEDTM":"2023-12-20 23:32:09","TRT01SDTM":"2020-12-20 05:32:09","TRT01EDTM":"2022-12-20 17:32:09","TRT02SDTM":"2022-12-20 17:32:09","TRT02EDTM":"2023-12-20 23:32:09","AP01SDTM":"2020-12-20 05:32:09","AP01EDTM":"2022-12-20 17:32:09","AP02SDTM":"2022-12-20 17:32:09","AP02EDTM":"2023-12-20 23:32:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7162,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.68967,"AVALU":"mg/L","BASE2":8.68967,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-05-23 05:32:09","ADY":154,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-364","SUBJID":"id-364","SITEID":"CHN-11","AGE":48,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.68839,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-20 05:32:09","TRTEDTM":"2023-12-20 23:32:09","TRT01SDTM":"2020-12-20 05:32:09","TRT01EDTM":"2022-12-20 17:32:09","TRT02SDTM":"2022-12-20 17:32:09","TRT02EDTM":"2023-12-20 23:32:09","AP01SDTM":"2020-12-20 05:32:09","AP01EDTM":"2022-12-20 17:32:09","AP02SDTM":"2022-12-20 17:32:09","AP02EDTM":"2023-12-20 23:32:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5815,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.25355,"AVALU":"mg/L","BASE2":8.68967,"BASE":7.25355,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.43612,"PCHG2":-16.52677,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2021-06-24 05:32:09","ADY":186,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-364","SUBJID":"id-364","SITEID":"CHN-11","AGE":48,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.68839,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-20 05:32:09","TRTEDTM":"2023-12-20 23:32:09","TRT01SDTM":"2020-12-20 05:32:09","TRT01EDTM":"2022-12-20 17:32:09","TRT02SDTM":"2022-12-20 17:32:09","TRT02EDTM":"2023-12-20 23:32:09","AP01SDTM":"2020-12-20 05:32:09","AP01EDTM":"2022-12-20 17:32:09","AP02SDTM":"2022-12-20 17:32:09","AP02EDTM":"2023-12-20 23:32:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8377,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.5313,"AVALU":"mg/L","BASE2":8.68967,"BASE":7.25355,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.84163,"PCHG2":32.70129,"CHG":4.27775,"PCHG":58.97467,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"1","BTOXGR":"-2","ADTM":"2021-09-04 05:32:09","ADY":258,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-364","SUBJID":"id-364","SITEID":"CHN-11","AGE":48,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.68839,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-20 05:32:09","TRTEDTM":"2023-12-20 23:32:09","TRT01SDTM":"2020-12-20 05:32:09","TRT01EDTM":"2022-12-20 17:32:09","TRT02SDTM":"2022-12-20 17:32:09","TRT02EDTM":"2023-12-20 23:32:09","AP01SDTM":"2020-12-20 05:32:09","AP01EDTM":"2022-12-20 17:32:09","AP02SDTM":"2022-12-20 17:32:09","AP02EDTM":"2023-12-20 23:32:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5170,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.644,"AVALU":"mg/L","BASE2":8.68967,"BASE":7.25355,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.04567,"PCHG2":-12.03351,"CHG":0.39045,"PCHG":5.38288,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-3","BTOXGR":"-2","ADTM":"2022-03-20 05:32:09","ADY":455,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-364","SUBJID":"id-364","SITEID":"CHN-11","AGE":48,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.68839,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-20 05:32:09","TRTEDTM":"2023-12-20 23:32:09","TRT01SDTM":"2020-12-20 05:32:09","TRT01EDTM":"2022-12-20 17:32:09","TRT02SDTM":"2022-12-20 17:32:09","TRT02EDTM":"2023-12-20 23:32:09","AP01SDTM":"2020-12-20 05:32:09","AP01EDTM":"2022-12-20 17:32:09","AP02SDTM":"2022-12-20 17:32:09","AP02EDTM":"2023-12-20 23:32:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6092,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.2495,"AVALU":"mg/L","BASE2":8.68967,"BASE":7.25355,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.44017,"PCHG2":-5.06541,"CHG":0.99595,"PCHG":13.73058,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-10-12 05:32:09","ADY":661,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-364","SUBJID":"id-364","SITEID":"CHN-11","AGE":48,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.68839,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-20 05:32:09","TRTEDTM":"2023-12-20 23:32:09","TRT01SDTM":"2020-12-20 05:32:09","TRT01EDTM":"2022-12-20 17:32:09","TRT02SDTM":"2022-12-20 17:32:09","TRT02EDTM":"2023-12-20 23:32:09","AP01SDTM":"2020-12-20 05:32:09","AP01EDTM":"2022-12-20 17:32:09","AP02SDTM":"2022-12-20 17:32:09","AP02EDTM":"2023-12-20 23:32:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":933,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.73877,"AVALU":"mg/L","BASE2":8.68967,"BASE":7.25355,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.9509,"PCHG2":-10.94286,"CHG":0.48522,"PCHG":6.68946,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2022-12-11 05:32:09","ADY":721,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-364","SUBJID":"id-364","SITEID":"CHN-11","AGE":48,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.68839,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-20 05:32:09","TRTEDTM":"2023-12-20 23:32:09","TRT01SDTM":"2020-12-20 05:32:09","TRT01EDTM":"2022-12-20 17:32:09","TRT02SDTM":"2022-12-20 17:32:09","TRT02EDTM":"2023-12-20 23:32:09","AP01SDTM":"2020-12-20 05:32:09","AP01EDTM":"2022-12-20 17:32:09","AP02SDTM":"2022-12-20 17:32:09","AP02EDTM":"2023-12-20 23:32:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6832,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.25703,"AVALU":"mg/L","BASE2":8.68967,"BASE":7.25355,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.56737,"PCHG2":6.5292,"CHG":2.00349,"PCHG":27.6208,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2023-07-26 05:32:09","ADY":948,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-364","SUBJID":"id-364","SITEID":"CHN-11","AGE":48,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.68839,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-20 05:32:09","TRTEDTM":"2023-12-20 23:32:09","TRT01SDTM":"2020-12-20 05:32:09","TRT01EDTM":"2022-12-20 17:32:09","TRT02SDTM":"2022-12-20 17:32:09","TRT02EDTM":"2023-12-20 23:32:09","AP01SDTM":"2020-12-20 05:32:09","AP01EDTM":"2022-12-20 17:32:09","AP02SDTM":"2022-12-20 17:32:09","AP02EDTM":"2023-12-20 23:32:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":479,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80824,"AVALU":"g/L","BASE2":2.80824,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-23 05:32:09","ADY":154,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-364","SUBJID":"id-364","SITEID":"CHN-11","AGE":48,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.68839,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-20 05:32:09","TRTEDTM":"2023-12-20 23:32:09","TRT01SDTM":"2020-12-20 05:32:09","TRT01EDTM":"2022-12-20 17:32:09","TRT02SDTM":"2022-12-20 17:32:09","TRT02EDTM":"2023-12-20 23:32:09","AP01SDTM":"2020-12-20 05:32:09","AP01EDTM":"2022-12-20 17:32:09","AP02SDTM":"2022-12-20 17:32:09","AP02EDTM":"2023-12-20 23:32:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4020,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7793,"AVALU":"g/L","BASE2":2.80824,"BASE":2.7793,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.02894,"PCHG2":-1.03041,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-24 05:32:09","ADY":186,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-364","SUBJID":"id-364","SITEID":"CHN-11","AGE":48,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.68839,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-20 05:32:09","TRTEDTM":"2023-12-20 23:32:09","TRT01SDTM":"2020-12-20 05:32:09","TRT01EDTM":"2022-12-20 17:32:09","TRT02SDTM":"2022-12-20 17:32:09","TRT02EDTM":"2023-12-20 23:32:09","AP01SDTM":"2020-12-20 05:32:09","AP01EDTM":"2022-12-20 17:32:09","AP02SDTM":"2022-12-20 17:32:09","AP02EDTM":"2023-12-20 23:32:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5080,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9345,"AVALU":"g/L","BASE2":2.80824,"BASE":2.7793,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12626,"PCHG2":4.49623,"CHG":0.1552,"PCHG":5.58418,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-04 05:32:09","ADY":258,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-364","SUBJID":"id-364","SITEID":"CHN-11","AGE":48,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.68839,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-20 05:32:09","TRTEDTM":"2023-12-20 23:32:09","TRT01SDTM":"2020-12-20 05:32:09","TRT01EDTM":"2022-12-20 17:32:09","TRT02SDTM":"2022-12-20 17:32:09","TRT02EDTM":"2023-12-20 23:32:09","AP01SDTM":"2020-12-20 05:32:09","AP01EDTM":"2022-12-20 17:32:09","AP02SDTM":"2022-12-20 17:32:09","AP02EDTM":"2023-12-20 23:32:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1826,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87697,"AVALU":"g/L","BASE2":2.80824,"BASE":2.7793,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06873,"PCHG2":2.44758,"CHG":0.09767,"PCHG":3.5142,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-20 05:32:09","ADY":455,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-364","SUBJID":"id-364","SITEID":"CHN-11","AGE":48,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.68839,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-20 05:32:09","TRTEDTM":"2023-12-20 23:32:09","TRT01SDTM":"2020-12-20 05:32:09","TRT01EDTM":"2022-12-20 17:32:09","TRT02SDTM":"2022-12-20 17:32:09","TRT02EDTM":"2023-12-20 23:32:09","AP01SDTM":"2020-12-20 05:32:09","AP01EDTM":"2022-12-20 17:32:09","AP02SDTM":"2022-12-20 17:32:09","AP02EDTM":"2023-12-20 23:32:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7662,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90928,"AVALU":"g/L","BASE2":2.80824,"BASE":2.7793,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10104,"PCHG2":3.59794,"CHG":0.12998,"PCHG":4.67654,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-12 05:32:09","ADY":661,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-364","SUBJID":"id-364","SITEID":"CHN-11","AGE":48,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.68839,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-20 05:32:09","TRTEDTM":"2023-12-20 23:32:09","TRT01SDTM":"2020-12-20 05:32:09","TRT01EDTM":"2022-12-20 17:32:09","TRT02SDTM":"2022-12-20 17:32:09","TRT02EDTM":"2023-12-20 23:32:09","AP01SDTM":"2020-12-20 05:32:09","AP01EDTM":"2022-12-20 17:32:09","AP02SDTM":"2022-12-20 17:32:09","AP02EDTM":"2023-12-20 23:32:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4248,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82032,"AVALU":"g/L","BASE2":2.80824,"BASE":2.7793,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01208,"PCHG2":0.43028,"CHG":0.04102,"PCHG":1.47591,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-11 05:32:09","ADY":721,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-364","SUBJID":"id-364","SITEID":"CHN-11","AGE":48,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.68839,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-20 05:32:09","TRTEDTM":"2023-12-20 23:32:09","TRT01SDTM":"2020-12-20 05:32:09","TRT01EDTM":"2022-12-20 17:32:09","TRT02SDTM":"2022-12-20 17:32:09","TRT02EDTM":"2023-12-20 23:32:09","AP01SDTM":"2020-12-20 05:32:09","AP01EDTM":"2022-12-20 17:32:09","AP02SDTM":"2022-12-20 17:32:09","AP02EDTM":"2023-12-20 23:32:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-20","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7739,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83955,"AVALU":"g/L","BASE2":2.80824,"BASE":2.7793,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03131,"PCHG2":1.11483,"CHG":0.06024,"PCHG":2.16758,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-26 05:32:09","ADY":948,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-377","SUBJID":"id-377","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.66603,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-10","TRTSDTM":"2020-01-10 16:28:00","TRT01SDTM":"2020-01-10 16:28:00","AP01SDTM":"2020-01-10 16:28:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3984,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.65999,"AVALU":"U/L","BASE2":14.65999,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-09 16:28:00","ADY":212,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-377","SUBJID":"id-377","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.66603,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-10","TRTSDTM":"2020-01-10 16:28:00","TRT01SDTM":"2020-01-10 16:28:00","AP01SDTM":"2020-01-10 16:28:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5690,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.5607,"AVALU":"U/L","BASE2":14.65999,"BASE":28.5607,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":13.9007,"PCHG2":94.82069,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-03 16:28:00","ADY":237,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-377","SUBJID":"id-377","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.66603,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-10","TRTSDTM":"2020-01-10 16:28:00","TRT01SDTM":"2020-01-10 16:28:00","AP01SDTM":"2020-01-10 16:28:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":908,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.67704,"AVALU":"U/L","BASE2":14.65999,"BASE":28.5607,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.98295,"PCHG2":-20.34758,"CHG":-16.88366,"PCHG":-59.11501,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-04 16:28:00","ADY":299,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-377","SUBJID":"id-377","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.66603,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-10","TRTSDTM":"2020-01-10 16:28:00","TRT01SDTM":"2020-01-10 16:28:00","AP01SDTM":"2020-01-10 16:28:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1118,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.31529,"AVALU":"U/L","BASE2":14.65999,"BASE":28.5607,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.3447,"PCHG2":-9.17259,"CHG":-15.24541,"PCHG":-53.37897,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-09 16:28:00","ADY":424,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-377","SUBJID":"id-377","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.66603,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-10","TRTSDTM":"2020-01-10 16:28:00","TRT01SDTM":"2020-01-10 16:28:00","AP01SDTM":"2020-01-10 16:28:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4212,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.63644,"AVALU":"U/L","BASE2":14.65999,"BASE":28.5607,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.02355,"PCHG2":-47.90964,"CHG":-20.92425,"PCHG":-73.26241,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-26 16:28:00","ADY":472,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-377","SUBJID":"id-377","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.66603,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-10","TRTSDTM":"2020-01-10 16:28:00","TRT01SDTM":"2020-01-10 16:28:00","AP01SDTM":"2020-01-10 16:28:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2667,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.53096,"AVALU":"U/L","BASE2":14.65999,"BASE":28.5607,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.87097,"PCHG2":5.94115,"CHG":-13.02973,"PCHG":-45.6212,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-21 16:28:00","ADY":589,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-377","SUBJID":"id-377","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.66603,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-10","TRTSDTM":"2020-01-10 16:28:00","TRT01SDTM":"2020-01-10 16:28:00","AP01SDTM":"2020-01-10 16:28:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8286,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.44616,"AVALU":"U/L","BASE2":14.65999,"BASE":28.5607,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.78617,"PCHG2":80.39685,"CHG":-2.11453,"PCHG":-7.40365,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-17 16:28:00","ADY":616,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-377","SUBJID":"id-377","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.66603,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-10","TRTSDTM":"2020-01-10 16:28:00","TRT01SDTM":"2020-01-10 16:28:00","AP01SDTM":"2020-01-10 16:28:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":402,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.27384,"AVALU":"mg/L","BASE2":8.27384,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-09 16:28:00","ADY":212,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-377","SUBJID":"id-377","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.66603,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-10","TRTSDTM":"2020-01-10 16:28:00","TRT01SDTM":"2020-01-10 16:28:00","AP01SDTM":"2020-01-10 16:28:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7071,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.27452,"AVALU":"mg/L","BASE2":8.27384,"BASE":9.27452,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.00068,"PCHG2":12.09451,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-03 16:28:00","ADY":237,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-377","SUBJID":"id-377","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.66603,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-10","TRTSDTM":"2020-01-10 16:28:00","TRT01SDTM":"2020-01-10 16:28:00","AP01SDTM":"2020-01-10 16:28:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6371,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.44302,"AVALU":"mg/L","BASE2":8.27384,"BASE":9.27452,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16918,"PCHG2":2.04475,"CHG":-0.8315,"PCHG":-8.96543,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-04 16:28:00","ADY":299,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-377","SUBJID":"id-377","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.66603,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-10","TRTSDTM":"2020-01-10 16:28:00","TRT01SDTM":"2020-01-10 16:28:00","AP01SDTM":"2020-01-10 16:28:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":200,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.48972,"AVALU":"mg/L","BASE2":8.27384,"BASE":9.27452,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.21588,"PCHG2":14.69542,"CHG":0.2152,"PCHG":2.32028,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-09 16:28:00","ADY":424,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-377","SUBJID":"id-377","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.66603,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-10","TRTSDTM":"2020-01-10 16:28:00","TRT01SDTM":"2020-01-10 16:28:00","AP01SDTM":"2020-01-10 16:28:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3166,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.53252,"AVALU":"mg/L","BASE2":8.27384,"BASE":9.27452,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.25868,"PCHG2":15.21275,"CHG":0.258,"PCHG":2.7818,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-26 16:28:00","ADY":472,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-377","SUBJID":"id-377","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.66603,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-10","TRTSDTM":"2020-01-10 16:28:00","TRT01SDTM":"2020-01-10 16:28:00","AP01SDTM":"2020-01-10 16:28:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1952,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.6722,"AVALU":"mg/L","BASE2":8.27384,"BASE":9.27452,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.60164,"PCHG2":-7.27164,"CHG":-1.60232,"PCHG":-17.27663,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-08-21 16:28:00","ADY":589,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-377","SUBJID":"id-377","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.66603,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-10","TRTSDTM":"2020-01-10 16:28:00","TRT01SDTM":"2020-01-10 16:28:00","AP01SDTM":"2020-01-10 16:28:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6074,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.54724,"AVALU":"mg/L","BASE2":8.27384,"BASE":9.27452,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.2734,"PCHG2":15.39062,"CHG":0.27272,"PCHG":2.94048,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-17 16:28:00","ADY":616,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-377","SUBJID":"id-377","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.66603,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-10","TRTSDTM":"2020-01-10 16:28:00","TRT01SDTM":"2020-01-10 16:28:00","AP01SDTM":"2020-01-10 16:28:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2849,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97682,"AVALU":"g/L","BASE2":2.97682,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-09 16:28:00","ADY":212,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-377","SUBJID":"id-377","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.66603,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-10","TRTSDTM":"2020-01-10 16:28:00","TRT01SDTM":"2020-01-10 16:28:00","AP01SDTM":"2020-01-10 16:28:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2972,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.71874,"AVALU":"g/L","BASE2":2.97682,"BASE":2.71874,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.25808,"PCHG2":-8.66963,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-03 16:28:00","ADY":237,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-377","SUBJID":"id-377","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.66603,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-10","TRTSDTM":"2020-01-10 16:28:00","TRT01SDTM":"2020-01-10 16:28:00","AP01SDTM":"2020-01-10 16:28:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5200,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90467,"AVALU":"g/L","BASE2":2.97682,"BASE":2.71874,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07215,"PCHG2":-2.42389,"CHG":0.18592,"PCHG":6.83862,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-04 16:28:00","ADY":299,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-377","SUBJID":"id-377","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.66603,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-10","TRTSDTM":"2020-01-10 16:28:00","TRT01SDTM":"2020-01-10 16:28:00","AP01SDTM":"2020-01-10 16:28:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4211,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81452,"AVALU":"g/L","BASE2":2.97682,"BASE":2.71874,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1623,"PCHG2":-5.45205,"CHG":0.09578,"PCHG":3.52301,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-09 16:28:00","ADY":424,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-377","SUBJID":"id-377","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.66603,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-10","TRTSDTM":"2020-01-10 16:28:00","TRT01SDTM":"2020-01-10 16:28:00","AP01SDTM":"2020-01-10 16:28:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5606,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95,"AVALU":"g/L","BASE2":2.97682,"BASE":2.71874,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02682,"PCHG2":-0.90102,"CHG":0.23126,"PCHG":8.50604,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-26 16:28:00","ADY":472,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-377","SUBJID":"id-377","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.66603,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-10","TRTSDTM":"2020-01-10 16:28:00","TRT01SDTM":"2020-01-10 16:28:00","AP01SDTM":"2020-01-10 16:28:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1544,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99396,"AVALU":"g/L","BASE2":2.97682,"BASE":2.71874,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01714,"PCHG2":0.57565,"CHG":0.27522,"PCHG":10.1229,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-21 16:28:00","ADY":589,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-377","SUBJID":"id-377","SITEID":"CHN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.66603,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-10","TRTSDTM":"2020-01-10 16:28:00","TRT01SDTM":"2020-01-10 16:28:00","AP01SDTM":"2020-01-10 16:28:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6042,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9519,"AVALU":"g/L","BASE2":2.97682,"BASE":2.71874,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02492,"PCHG2":-0.8372,"CHG":0.23316,"PCHG":8.57593,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-17 16:28:00","ADY":616,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-379","SUBJID":"id-379","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.84651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-29","TRTSDTM":"2019-07-30 00:43:21","TRTEDTM":"2022-07-29 18:43:21","TRT01SDTM":"2019-07-30 00:43:21","TRT01EDTM":"2021-07-29 12:43:21","TRT02SDTM":"2021-07-29 12:43:21","TRT02EDTM":"2022-07-29 18:43:21","AP01SDTM":"2019-07-30 00:43:21","AP01EDTM":"2021-07-29 12:43:21","AP02SDTM":"2021-07-29 12:43:21","AP02EDTM":"2022-07-29 18:43:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-24","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2172,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.01105,"AVALU":"U/L","BASE2":18.01105,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-24 00:43:21","ADY":56,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-379","SUBJID":"id-379","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.84651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-29","TRTSDTM":"2019-07-30 00:43:21","TRTEDTM":"2022-07-29 18:43:21","TRT01SDTM":"2019-07-30 00:43:21","TRT01EDTM":"2021-07-29 12:43:21","TRT02SDTM":"2021-07-29 12:43:21","TRT02EDTM":"2022-07-29 18:43:21","AP01SDTM":"2019-07-30 00:43:21","AP01EDTM":"2021-07-29 12:43:21","AP02SDTM":"2021-07-29 12:43:21","AP02EDTM":"2022-07-29 18:43:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-24","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1387,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.24333,"AVALU":"U/L","BASE2":18.01105,"BASE":24.24333,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":6.23228,"PCHG2":34.60251,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-02 00:43:21","ADY":95,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-379","SUBJID":"id-379","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.84651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-29","TRTSDTM":"2019-07-30 00:43:21","TRTEDTM":"2022-07-29 18:43:21","TRT01SDTM":"2019-07-30 00:43:21","TRT01EDTM":"2021-07-29 12:43:21","TRT02SDTM":"2021-07-29 12:43:21","TRT02EDTM":"2022-07-29 18:43:21","AP01SDTM":"2019-07-30 00:43:21","AP01EDTM":"2021-07-29 12:43:21","AP02SDTM":"2021-07-29 12:43:21","AP02EDTM":"2022-07-29 18:43:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-24","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":295,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.18752,"AVALU":"U/L","BASE2":18.01105,"BASE":24.24333,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-15.82353,"PCHG2":-87.85456,"CHG":-22.05581,"PCHG":-90.97681,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-03-06 00:43:21","ADY":220,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-379","SUBJID":"id-379","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.84651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-29","TRTSDTM":"2019-07-30 00:43:21","TRTEDTM":"2022-07-29 18:43:21","TRT01SDTM":"2019-07-30 00:43:21","TRT01EDTM":"2021-07-29 12:43:21","TRT02SDTM":"2021-07-29 12:43:21","TRT02EDTM":"2022-07-29 18:43:21","AP01SDTM":"2019-07-30 00:43:21","AP01EDTM":"2021-07-29 12:43:21","AP02SDTM":"2021-07-29 12:43:21","AP02EDTM":"2022-07-29 18:43:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-24","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7317,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.3608,"AVALU":"U/L","BASE2":18.01105,"BASE":24.24333,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.34975,"PCHG2":85.22403,"CHG":9.11747,"PCHG":37.60815,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-06 00:43:21","ADY":495,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-379","SUBJID":"id-379","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.84651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-29","TRTSDTM":"2019-07-30 00:43:21","TRTEDTM":"2022-07-29 18:43:21","TRT01SDTM":"2019-07-30 00:43:21","TRT01EDTM":"2021-07-29 12:43:21","TRT02SDTM":"2021-07-29 12:43:21","TRT02EDTM":"2022-07-29 18:43:21","AP01SDTM":"2019-07-30 00:43:21","AP01EDTM":"2021-07-29 12:43:21","AP02SDTM":"2021-07-29 12:43:21","AP02EDTM":"2022-07-29 18:43:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-24","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1076,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.84771,"AVALU":"U/L","BASE2":18.01105,"BASE":24.24333,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.83665,"PCHG2":32.40595,"CHG":-0.39562,"PCHG":-1.63188,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-21 00:43:21","ADY":510,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-379","SUBJID":"id-379","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.84651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-29","TRTSDTM":"2019-07-30 00:43:21","TRTEDTM":"2022-07-29 18:43:21","TRT01SDTM":"2019-07-30 00:43:21","TRT01EDTM":"2021-07-29 12:43:21","TRT02SDTM":"2021-07-29 12:43:21","TRT02EDTM":"2022-07-29 18:43:21","AP01SDTM":"2019-07-30 00:43:21","AP01EDTM":"2021-07-29 12:43:21","AP02SDTM":"2021-07-29 12:43:21","AP02EDTM":"2022-07-29 18:43:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-24","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8280,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.56032,"AVALU":"U/L","BASE2":18.01105,"BASE":24.24333,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.45073,"PCHG2":-13.60681,"CHG":-8.68301,"PCHG":-35.81606,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-22 00:43:21","ADY":785,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-379","SUBJID":"id-379","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.84651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-29","TRTSDTM":"2019-07-30 00:43:21","TRTEDTM":"2022-07-29 18:43:21","TRT01SDTM":"2019-07-30 00:43:21","TRT01EDTM":"2021-07-29 12:43:21","TRT02SDTM":"2021-07-29 12:43:21","TRT02EDTM":"2022-07-29 18:43:21","AP01SDTM":"2019-07-30 00:43:21","AP01EDTM":"2021-07-29 12:43:21","AP02SDTM":"2021-07-29 12:43:21","AP02EDTM":"2022-07-29 18:43:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-24","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":829,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.49614,"AVALU":"U/L","BASE2":18.01105,"BASE":24.24333,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.48509,"PCHG2":91.52763,"CHG":10.25281,"PCHG":42.29128,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-26 00:43:21","ADY":970,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-379","SUBJID":"id-379","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.84651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-29","TRTSDTM":"2019-07-30 00:43:21","TRTEDTM":"2022-07-29 18:43:21","TRT01SDTM":"2019-07-30 00:43:21","TRT01EDTM":"2021-07-29 12:43:21","TRT02SDTM":"2021-07-29 12:43:21","TRT02EDTM":"2022-07-29 18:43:21","AP01SDTM":"2019-07-30 00:43:21","AP01EDTM":"2021-07-29 12:43:21","AP02SDTM":"2021-07-29 12:43:21","AP02EDTM":"2022-07-29 18:43:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-24","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6240,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.23098,"AVALU":"mg/L","BASE2":9.23098,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-24 00:43:21","ADY":56,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-379","SUBJID":"id-379","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.84651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-29","TRTSDTM":"2019-07-30 00:43:21","TRTEDTM":"2022-07-29 18:43:21","TRT01SDTM":"2019-07-30 00:43:21","TRT01EDTM":"2021-07-29 12:43:21","TRT02SDTM":"2021-07-29 12:43:21","TRT02EDTM":"2022-07-29 18:43:21","AP01SDTM":"2019-07-30 00:43:21","AP01EDTM":"2021-07-29 12:43:21","AP02SDTM":"2021-07-29 12:43:21","AP02EDTM":"2022-07-29 18:43:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-24","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2878,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.88741,"AVALU":"mg/L","BASE2":9.23098,"BASE":8.88741,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.34358,"PCHG2":-3.72199,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-02 00:43:21","ADY":95,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-379","SUBJID":"id-379","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.84651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-29","TRTSDTM":"2019-07-30 00:43:21","TRTEDTM":"2022-07-29 18:43:21","TRT01SDTM":"2019-07-30 00:43:21","TRT01EDTM":"2021-07-29 12:43:21","TRT02SDTM":"2021-07-29 12:43:21","TRT02EDTM":"2022-07-29 18:43:21","AP01SDTM":"2019-07-30 00:43:21","AP01EDTM":"2021-07-29 12:43:21","AP02SDTM":"2021-07-29 12:43:21","AP02EDTM":"2022-07-29 18:43:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-24","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":545,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.71342,"AVALU":"mg/L","BASE2":9.23098,"BASE":8.88741,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.51756,"PCHG2":-5.60682,"CHG":-0.17399,"PCHG":-1.95769,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-06 00:43:21","ADY":220,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-379","SUBJID":"id-379","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.84651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-29","TRTSDTM":"2019-07-30 00:43:21","TRTEDTM":"2022-07-29 18:43:21","TRT01SDTM":"2019-07-30 00:43:21","TRT01EDTM":"2021-07-29 12:43:21","TRT02SDTM":"2021-07-29 12:43:21","TRT02EDTM":"2022-07-29 18:43:21","AP01SDTM":"2019-07-30 00:43:21","AP01EDTM":"2021-07-29 12:43:21","AP02SDTM":"2021-07-29 12:43:21","AP02EDTM":"2022-07-29 18:43:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-24","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4502,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.64958,"AVALU":"mg/L","BASE2":9.23098,"BASE":8.88741,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.5814,"PCHG2":-17.13144,"CHG":-1.23782,"PCHG":-13.92784,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-12-06 00:43:21","ADY":495,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-379","SUBJID":"id-379","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.84651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-29","TRTSDTM":"2019-07-30 00:43:21","TRTEDTM":"2022-07-29 18:43:21","TRT01SDTM":"2019-07-30 00:43:21","TRT01EDTM":"2021-07-29 12:43:21","TRT02SDTM":"2021-07-29 12:43:21","TRT02EDTM":"2022-07-29 18:43:21","AP01SDTM":"2019-07-30 00:43:21","AP01EDTM":"2021-07-29 12:43:21","AP02SDTM":"2021-07-29 12:43:21","AP02EDTM":"2022-07-29 18:43:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-24","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8034,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.08938,"AVALU":"mg/L","BASE2":9.23098,"BASE":8.88741,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1416,"PCHG2":-1.534,"CHG":0.20197,"PCHG":2.27258,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-21 00:43:21","ADY":510,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-379","SUBJID":"id-379","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.84651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-29","TRTSDTM":"2019-07-30 00:43:21","TRTEDTM":"2022-07-29 18:43:21","TRT01SDTM":"2019-07-30 00:43:21","TRT01EDTM":"2021-07-29 12:43:21","TRT02SDTM":"2021-07-29 12:43:21","TRT02EDTM":"2022-07-29 18:43:21","AP01SDTM":"2019-07-30 00:43:21","AP01EDTM":"2021-07-29 12:43:21","AP02SDTM":"2021-07-29 12:43:21","AP02EDTM":"2022-07-29 18:43:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-24","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2729,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.85275,"AVALU":"mg/L","BASE2":9.23098,"BASE":8.88741,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.37823,"PCHG2":-4.09744,"CHG":-0.03466,"PCHG":-0.38997,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-22 00:43:21","ADY":785,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-379","SUBJID":"id-379","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.84651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-29","TRTSDTM":"2019-07-30 00:43:21","TRTEDTM":"2022-07-29 18:43:21","TRT01SDTM":"2019-07-30 00:43:21","TRT01EDTM":"2021-07-29 12:43:21","TRT02SDTM":"2021-07-29 12:43:21","TRT02EDTM":"2022-07-29 18:43:21","AP01SDTM":"2019-07-30 00:43:21","AP01EDTM":"2021-07-29 12:43:21","AP02SDTM":"2021-07-29 12:43:21","AP02EDTM":"2022-07-29 18:43:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-24","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5003,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.63385,"AVALU":"mg/L","BASE2":9.23098,"BASE":8.88741,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.40286,"PCHG2":4.36423,"CHG":0.74644,"PCHG":8.39882,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-26 00:43:21","ADY":970,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-379","SUBJID":"id-379","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.84651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-29","TRTSDTM":"2019-07-30 00:43:21","TRTEDTM":"2022-07-29 18:43:21","TRT01SDTM":"2019-07-30 00:43:21","TRT01EDTM":"2021-07-29 12:43:21","TRT02SDTM":"2021-07-29 12:43:21","TRT02EDTM":"2022-07-29 18:43:21","AP01SDTM":"2019-07-30 00:43:21","AP01EDTM":"2021-07-29 12:43:21","AP02SDTM":"2021-07-29 12:43:21","AP02EDTM":"2022-07-29 18:43:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-24","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3240,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95843,"AVALU":"g/L","BASE2":2.95843,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-24 00:43:21","ADY":56,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-379","SUBJID":"id-379","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.84651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-29","TRTSDTM":"2019-07-30 00:43:21","TRTEDTM":"2022-07-29 18:43:21","TRT01SDTM":"2019-07-30 00:43:21","TRT01EDTM":"2021-07-29 12:43:21","TRT02SDTM":"2021-07-29 12:43:21","TRT02EDTM":"2022-07-29 18:43:21","AP01SDTM":"2019-07-30 00:43:21","AP01EDTM":"2021-07-29 12:43:21","AP02SDTM":"2021-07-29 12:43:21","AP02EDTM":"2022-07-29 18:43:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-24","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1322,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9326,"AVALU":"g/L","BASE2":2.95843,"BASE":2.9326,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.02583,"PCHG2":-0.87315,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-02 00:43:21","ADY":95,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-379","SUBJID":"id-379","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.84651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-29","TRTSDTM":"2019-07-30 00:43:21","TRTEDTM":"2022-07-29 18:43:21","TRT01SDTM":"2019-07-30 00:43:21","TRT01EDTM":"2021-07-29 12:43:21","TRT02SDTM":"2021-07-29 12:43:21","TRT02EDTM":"2022-07-29 18:43:21","AP01SDTM":"2019-07-30 00:43:21","AP01EDTM":"2021-07-29 12:43:21","AP02SDTM":"2021-07-29 12:43:21","AP02EDTM":"2022-07-29 18:43:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-24","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7191,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99672,"AVALU":"g/L","BASE2":2.95843,"BASE":2.9326,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03829,"PCHG2":1.29418,"CHG":0.06412,"PCHG":2.18642,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-06 00:43:21","ADY":220,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-379","SUBJID":"id-379","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.84651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-29","TRTSDTM":"2019-07-30 00:43:21","TRTEDTM":"2022-07-29 18:43:21","TRT01SDTM":"2019-07-30 00:43:21","TRT01EDTM":"2021-07-29 12:43:21","TRT02SDTM":"2021-07-29 12:43:21","TRT02EDTM":"2022-07-29 18:43:21","AP01SDTM":"2019-07-30 00:43:21","AP01EDTM":"2021-07-29 12:43:21","AP02SDTM":"2021-07-29 12:43:21","AP02EDTM":"2022-07-29 18:43:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-24","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5600,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89933,"AVALU":"g/L","BASE2":2.95843,"BASE":2.9326,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05911,"PCHG2":-1.99795,"CHG":-0.03328,"PCHG":-1.13471,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-06 00:43:21","ADY":495,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-379","SUBJID":"id-379","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.84651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-29","TRTSDTM":"2019-07-30 00:43:21","TRTEDTM":"2022-07-29 18:43:21","TRT01SDTM":"2019-07-30 00:43:21","TRT01EDTM":"2021-07-29 12:43:21","TRT02SDTM":"2021-07-29 12:43:21","TRT02EDTM":"2022-07-29 18:43:21","AP01SDTM":"2019-07-30 00:43:21","AP01EDTM":"2021-07-29 12:43:21","AP02SDTM":"2021-07-29 12:43:21","AP02EDTM":"2022-07-29 18:43:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-24","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6607,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79986,"AVALU":"g/L","BASE2":2.95843,"BASE":2.9326,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15857,"PCHG2":-5.36008,"CHG":-0.13274,"PCHG":-4.52645,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-21 00:43:21","ADY":510,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-379","SUBJID":"id-379","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.84651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-29","TRTSDTM":"2019-07-30 00:43:21","TRTEDTM":"2022-07-29 18:43:21","TRT01SDTM":"2019-07-30 00:43:21","TRT01EDTM":"2021-07-29 12:43:21","TRT02SDTM":"2021-07-29 12:43:21","TRT02EDTM":"2022-07-29 18:43:21","AP01SDTM":"2019-07-30 00:43:21","AP01EDTM":"2021-07-29 12:43:21","AP02SDTM":"2021-07-29 12:43:21","AP02EDTM":"2022-07-29 18:43:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-24","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6435,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9533,"AVALU":"g/L","BASE2":2.95843,"BASE":2.9326,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00513,"PCHG2":-0.17346,"CHG":0.0207,"PCHG":0.70585,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-22 00:43:21","ADY":785,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-379","SUBJID":"id-379","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.84651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-29","TRTSDTM":"2019-07-30 00:43:21","TRTEDTM":"2022-07-29 18:43:21","TRT01SDTM":"2019-07-30 00:43:21","TRT01EDTM":"2021-07-29 12:43:21","TRT02SDTM":"2021-07-29 12:43:21","TRT02EDTM":"2022-07-29 18:43:21","AP01SDTM":"2019-07-30 00:43:21","AP01EDTM":"2021-07-29 12:43:21","AP02SDTM":"2021-07-29 12:43:21","AP02EDTM":"2022-07-29 18:43:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-24","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":616,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.70922,"AVALU":"g/L","BASE2":2.95843,"BASE":2.9326,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.24921,"PCHG2":-8.42374,"CHG":-0.22338,"PCHG":-7.61709,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-26 00:43:21","ADY":970,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-38","SUBJID":"id-38","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.48993,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-13","TRTSDTM":"2019-06-17 00:54:30","TRTEDTM":"2022-06-16 18:54:30","TRT01SDTM":"2019-06-17 00:54:30","TRT01EDTM":"2021-06-16 12:54:30","TRT02SDTM":"2021-06-16 12:54:30","TRT02EDTM":"2022-06-16 18:54:30","AP01SDTM":"2019-06-17 00:54:30","AP01EDTM":"2021-06-16 12:54:30","AP02SDTM":"2021-06-16 12:54:30","AP02EDTM":"2022-06-16 18:54:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-16","EOSDY":1096,"LSTALVDT":"2022-07-08","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3538,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.33024,"AVALU":"U/L","BASE2":32.33024,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-30 00:54:30","ADY":348,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-38","SUBJID":"id-38","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.48993,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-13","TRTSDTM":"2019-06-17 00:54:30","TRTEDTM":"2022-06-16 18:54:30","TRT01SDTM":"2019-06-17 00:54:30","TRT01EDTM":"2021-06-16 12:54:30","TRT02SDTM":"2021-06-16 12:54:30","TRT02EDTM":"2022-06-16 18:54:30","AP01SDTM":"2019-06-17 00:54:30","AP01EDTM":"2021-06-16 12:54:30","AP02SDTM":"2021-06-16 12:54:30","AP02EDTM":"2022-06-16 18:54:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-16","EOSDY":1096,"LSTALVDT":"2022-07-08","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2655,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.29977,"AVALU":"U/L","BASE2":32.33024,"BASE":9.29977,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-23.03047,"PCHG2":-71.23508,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-18 00:54:30","ADY":671,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-38","SUBJID":"id-38","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.48993,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-13","TRTSDTM":"2019-06-17 00:54:30","TRTEDTM":"2022-06-16 18:54:30","TRT01SDTM":"2019-06-17 00:54:30","TRT01EDTM":"2021-06-16 12:54:30","TRT02SDTM":"2021-06-16 12:54:30","TRT02EDTM":"2022-06-16 18:54:30","AP01SDTM":"2019-06-17 00:54:30","AP01EDTM":"2021-06-16 12:54:30","AP02SDTM":"2021-06-16 12:54:30","AP02EDTM":"2022-06-16 18:54:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-16","EOSDY":1096,"LSTALVDT":"2022-07-08","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2597,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.58935,"AVALU":"U/L","BASE2":32.33024,"BASE":9.29977,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.74089,"PCHG2":-23.94319,"CHG":15.28958,"PCHG":164.40822,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-25 00:54:30","ADY":708,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-38","SUBJID":"id-38","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.48993,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-13","TRTSDTM":"2019-06-17 00:54:30","TRTEDTM":"2022-06-16 18:54:30","TRT01SDTM":"2019-06-17 00:54:30","TRT01EDTM":"2021-06-16 12:54:30","TRT02SDTM":"2021-06-16 12:54:30","TRT02EDTM":"2022-06-16 18:54:30","AP01SDTM":"2019-06-17 00:54:30","AP01EDTM":"2021-06-16 12:54:30","AP02SDTM":"2021-06-16 12:54:30","AP02EDTM":"2022-06-16 18:54:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-16","EOSDY":1096,"LSTALVDT":"2022-07-08","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1388,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.49923,"AVALU":"U/L","BASE2":32.33024,"BASE":9.29977,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.83101,"PCHG2":-42.78042,"CHG":9.19946,"PCHG":98.9214,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-11 00:54:30","ADY":878,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-38","SUBJID":"id-38","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.48993,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-13","TRTSDTM":"2019-06-17 00:54:30","TRTEDTM":"2022-06-16 18:54:30","TRT01SDTM":"2019-06-17 00:54:30","TRT01EDTM":"2021-06-16 12:54:30","TRT02SDTM":"2021-06-16 12:54:30","TRT02EDTM":"2022-06-16 18:54:30","AP01SDTM":"2019-06-17 00:54:30","AP01EDTM":"2021-06-16 12:54:30","AP02SDTM":"2021-06-16 12:54:30","AP02EDTM":"2022-06-16 18:54:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-16","EOSDY":1096,"LSTALVDT":"2022-07-08","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3635,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.28899,"AVALU":"U/L","BASE2":32.33024,"BASE":9.29977,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.04124,"PCHG2":-37.24452,"CHG":10.98923,"PCHG":118.1667,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-22 00:54:30","ADY":919,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-38","SUBJID":"id-38","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.48993,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-13","TRTSDTM":"2019-06-17 00:54:30","TRTEDTM":"2022-06-16 18:54:30","TRT01SDTM":"2019-06-17 00:54:30","TRT01EDTM":"2021-06-16 12:54:30","TRT02SDTM":"2021-06-16 12:54:30","TRT02EDTM":"2022-06-16 18:54:30","AP01SDTM":"2019-06-17 00:54:30","AP01EDTM":"2021-06-16 12:54:30","AP02SDTM":"2021-06-16 12:54:30","AP02EDTM":"2022-06-16 18:54:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-16","EOSDY":1096,"LSTALVDT":"2022-07-08","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1850,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.47738,"AVALU":"U/L","BASE2":32.33024,"BASE":9.29977,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.85286,"PCHG2":-2.63795,"CHG":22.17761,"PCHG":238.47496,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-13 00:54:30","ADY":972,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-38","SUBJID":"id-38","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.48993,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-13","TRTSDTM":"2019-06-17 00:54:30","TRTEDTM":"2022-06-16 18:54:30","TRT01SDTM":"2019-06-17 00:54:30","TRT01EDTM":"2021-06-16 12:54:30","TRT02SDTM":"2021-06-16 12:54:30","TRT02EDTM":"2022-06-16 18:54:30","AP01SDTM":"2019-06-17 00:54:30","AP01EDTM":"2021-06-16 12:54:30","AP02SDTM":"2021-06-16 12:54:30","AP02EDTM":"2022-06-16 18:54:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-16","EOSDY":1096,"LSTALVDT":"2022-07-08","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":88,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.29022,"AVALU":"U/L","BASE2":32.33024,"BASE":9.29977,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-15.04001,"PCHG2":-46.51996,"CHG":7.99046,"PCHG":85.92104,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-26 00:54:30","ADY":985,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-38","SUBJID":"id-38","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.48993,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-13","TRTSDTM":"2019-06-17 00:54:30","TRTEDTM":"2022-06-16 18:54:30","TRT01SDTM":"2019-06-17 00:54:30","TRT01EDTM":"2021-06-16 12:54:30","TRT02SDTM":"2021-06-16 12:54:30","TRT02EDTM":"2022-06-16 18:54:30","AP01SDTM":"2019-06-17 00:54:30","AP01EDTM":"2021-06-16 12:54:30","AP02SDTM":"2021-06-16 12:54:30","AP02EDTM":"2022-06-16 18:54:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-16","EOSDY":1096,"LSTALVDT":"2022-07-08","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4863,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.76122,"AVALU":"mg/L","BASE2":8.76122,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-30 00:54:30","ADY":348,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-38","SUBJID":"id-38","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.48993,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-13","TRTSDTM":"2019-06-17 00:54:30","TRTEDTM":"2022-06-16 18:54:30","TRT01SDTM":"2019-06-17 00:54:30","TRT01EDTM":"2021-06-16 12:54:30","TRT02SDTM":"2021-06-16 12:54:30","TRT02EDTM":"2022-06-16 18:54:30","AP01SDTM":"2019-06-17 00:54:30","AP01EDTM":"2021-06-16 12:54:30","AP02SDTM":"2021-06-16 12:54:30","AP02EDTM":"2022-06-16 18:54:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-16","EOSDY":1096,"LSTALVDT":"2022-07-08","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3330,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.3892,"AVALU":"mg/L","BASE2":8.76122,"BASE":8.3892,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.37202,"PCHG2":-4.24619,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-18 00:54:30","ADY":671,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-38","SUBJID":"id-38","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.48993,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-13","TRTSDTM":"2019-06-17 00:54:30","TRTEDTM":"2022-06-16 18:54:30","TRT01SDTM":"2019-06-17 00:54:30","TRT01EDTM":"2021-06-16 12:54:30","TRT02SDTM":"2021-06-16 12:54:30","TRT02EDTM":"2022-06-16 18:54:30","AP01SDTM":"2019-06-17 00:54:30","AP01EDTM":"2021-06-16 12:54:30","AP02SDTM":"2021-06-16 12:54:30","AP02EDTM":"2022-06-16 18:54:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-16","EOSDY":1096,"LSTALVDT":"2022-07-08","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7141,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.47159,"AVALU":"mg/L","BASE2":8.76122,"BASE":8.3892,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.71037,"PCHG2":8.10807,"CHG":1.08238,"PCHG":12.90211,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-25 00:54:30","ADY":708,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-38","SUBJID":"id-38","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.48993,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-13","TRTSDTM":"2019-06-17 00:54:30","TRTEDTM":"2022-06-16 18:54:30","TRT01SDTM":"2019-06-17 00:54:30","TRT01EDTM":"2021-06-16 12:54:30","TRT02SDTM":"2021-06-16 12:54:30","TRT02EDTM":"2022-06-16 18:54:30","AP01SDTM":"2019-06-17 00:54:30","AP01EDTM":"2021-06-16 12:54:30","AP02SDTM":"2021-06-16 12:54:30","AP02EDTM":"2022-06-16 18:54:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-16","EOSDY":1096,"LSTALVDT":"2022-07-08","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3876,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.68211,"AVALU":"mg/L","BASE2":8.76122,"BASE":8.3892,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07911,"PCHG2":-0.90292,"CHG":0.29291,"PCHG":3.49153,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-11 00:54:30","ADY":878,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-38","SUBJID":"id-38","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.48993,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-13","TRTSDTM":"2019-06-17 00:54:30","TRTEDTM":"2022-06-16 18:54:30","TRT01SDTM":"2019-06-17 00:54:30","TRT01EDTM":"2021-06-16 12:54:30","TRT02SDTM":"2021-06-16 12:54:30","TRT02EDTM":"2022-06-16 18:54:30","AP01SDTM":"2019-06-17 00:54:30","AP01EDTM":"2021-06-16 12:54:30","AP02SDTM":"2021-06-16 12:54:30","AP02EDTM":"2022-06-16 18:54:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-16","EOSDY":1096,"LSTALVDT":"2022-07-08","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4153,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.5679,"AVALU":"mg/L","BASE2":8.76122,"BASE":8.3892,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.80668,"PCHG2":9.20736,"CHG":1.1787,"PCHG":14.05015,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-22 00:54:30","ADY":919,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-38","SUBJID":"id-38","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.48993,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-13","TRTSDTM":"2019-06-17 00:54:30","TRTEDTM":"2022-06-16 18:54:30","TRT01SDTM":"2019-06-17 00:54:30","TRT01EDTM":"2021-06-16 12:54:30","TRT02SDTM":"2021-06-16 12:54:30","TRT02EDTM":"2022-06-16 18:54:30","AP01SDTM":"2019-06-17 00:54:30","AP01EDTM":"2021-06-16 12:54:30","AP02SDTM":"2021-06-16 12:54:30","AP02EDTM":"2022-06-16 18:54:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-16","EOSDY":1096,"LSTALVDT":"2022-07-08","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6120,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.26537,"AVALU":"mg/L","BASE2":8.76122,"BASE":8.3892,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.49585,"PCHG2":-5.6596,"CHG":-0.12383,"PCHG":-1.47608,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-13 00:54:30","ADY":972,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-38","SUBJID":"id-38","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.48993,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-13","TRTSDTM":"2019-06-17 00:54:30","TRTEDTM":"2022-06-16 18:54:30","TRT01SDTM":"2019-06-17 00:54:30","TRT01EDTM":"2021-06-16 12:54:30","TRT02SDTM":"2021-06-16 12:54:30","TRT02EDTM":"2022-06-16 18:54:30","AP01SDTM":"2019-06-17 00:54:30","AP01EDTM":"2021-06-16 12:54:30","AP02SDTM":"2021-06-16 12:54:30","AP02EDTM":"2022-06-16 18:54:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-16","EOSDY":1096,"LSTALVDT":"2022-07-08","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6770,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.75455,"AVALU":"mg/L","BASE2":8.76122,"BASE":8.3892,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00668,"PCHG2":-0.07619,"CHG":0.36534,"PCHG":4.35492,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-26 00:54:30","ADY":985,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-38","SUBJID":"id-38","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.48993,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-13","TRTSDTM":"2019-06-17 00:54:30","TRTEDTM":"2022-06-16 18:54:30","TRT01SDTM":"2019-06-17 00:54:30","TRT01EDTM":"2021-06-16 12:54:30","TRT02SDTM":"2021-06-16 12:54:30","TRT02EDTM":"2022-06-16 18:54:30","AP01SDTM":"2019-06-17 00:54:30","AP01EDTM":"2021-06-16 12:54:30","AP02SDTM":"2021-06-16 12:54:30","AP02EDTM":"2022-06-16 18:54:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-16","EOSDY":1096,"LSTALVDT":"2022-07-08","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2053,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99382,"AVALU":"g/L","BASE2":2.99382,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-30 00:54:30","ADY":348,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-38","SUBJID":"id-38","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.48993,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-13","TRTSDTM":"2019-06-17 00:54:30","TRTEDTM":"2022-06-16 18:54:30","TRT01SDTM":"2019-06-17 00:54:30","TRT01EDTM":"2021-06-16 12:54:30","TRT02SDTM":"2021-06-16 12:54:30","TRT02EDTM":"2022-06-16 18:54:30","AP01SDTM":"2019-06-17 00:54:30","AP01EDTM":"2021-06-16 12:54:30","AP02SDTM":"2021-06-16 12:54:30","AP02EDTM":"2022-06-16 18:54:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-16","EOSDY":1096,"LSTALVDT":"2022-07-08","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7678,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80342,"AVALU":"g/L","BASE2":2.99382,"BASE":2.80342,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.1904,"PCHG2":-6.35974,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-18 00:54:30","ADY":671,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-38","SUBJID":"id-38","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.48993,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-13","TRTSDTM":"2019-06-17 00:54:30","TRTEDTM":"2022-06-16 18:54:30","TRT01SDTM":"2019-06-17 00:54:30","TRT01EDTM":"2021-06-16 12:54:30","TRT02SDTM":"2021-06-16 12:54:30","TRT02EDTM":"2022-06-16 18:54:30","AP01SDTM":"2019-06-17 00:54:30","AP01EDTM":"2021-06-16 12:54:30","AP02SDTM":"2021-06-16 12:54:30","AP02EDTM":"2022-06-16 18:54:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-16","EOSDY":1096,"LSTALVDT":"2022-07-08","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7025,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94333,"AVALU":"g/L","BASE2":2.99382,"BASE":2.80342,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05049,"PCHG2":-1.68657,"CHG":0.13991,"PCHG":4.99055,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-25 00:54:30","ADY":708,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-38","SUBJID":"id-38","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.48993,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-13","TRTSDTM":"2019-06-17 00:54:30","TRTEDTM":"2022-06-16 18:54:30","TRT01SDTM":"2019-06-17 00:54:30","TRT01EDTM":"2021-06-16 12:54:30","TRT02SDTM":"2021-06-16 12:54:30","TRT02EDTM":"2022-06-16 18:54:30","AP01SDTM":"2019-06-17 00:54:30","AP01EDTM":"2021-06-16 12:54:30","AP02SDTM":"2021-06-16 12:54:30","AP02EDTM":"2022-06-16 18:54:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-16","EOSDY":1096,"LSTALVDT":"2022-07-08","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1277,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80071,"AVALU":"g/L","BASE2":2.99382,"BASE":2.80342,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19311,"PCHG2":-6.45021,"CHG":-0.00271,"PCHG":-0.09662,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-11 00:54:30","ADY":878,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-38","SUBJID":"id-38","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.48993,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-13","TRTSDTM":"2019-06-17 00:54:30","TRTEDTM":"2022-06-16 18:54:30","TRT01SDTM":"2019-06-17 00:54:30","TRT01EDTM":"2021-06-16 12:54:30","TRT02SDTM":"2021-06-16 12:54:30","TRT02EDTM":"2022-06-16 18:54:30","AP01SDTM":"2019-06-17 00:54:30","AP01EDTM":"2021-06-16 12:54:30","AP02SDTM":"2021-06-16 12:54:30","AP02EDTM":"2022-06-16 18:54:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-16","EOSDY":1096,"LSTALVDT":"2022-07-08","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7949,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94188,"AVALU":"g/L","BASE2":2.99382,"BASE":2.80342,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05194,"PCHG2":-1.73491,"CHG":0.13846,"PCHG":4.93893,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-22 00:54:30","ADY":919,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-38","SUBJID":"id-38","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.48993,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-13","TRTSDTM":"2019-06-17 00:54:30","TRTEDTM":"2022-06-16 18:54:30","TRT01SDTM":"2019-06-17 00:54:30","TRT01EDTM":"2021-06-16 12:54:30","TRT02SDTM":"2021-06-16 12:54:30","TRT02EDTM":"2022-06-16 18:54:30","AP01SDTM":"2019-06-17 00:54:30","AP01EDTM":"2021-06-16 12:54:30","AP02SDTM":"2021-06-16 12:54:30","AP02EDTM":"2022-06-16 18:54:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-16","EOSDY":1096,"LSTALVDT":"2022-07-08","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3112,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93011,"AVALU":"g/L","BASE2":2.99382,"BASE":2.80342,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06371,"PCHG2":-2.12805,"CHG":0.12669,"PCHG":4.51909,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-13 00:54:30","ADY":972,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-38","SUBJID":"id-38","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.48993,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-13","TRTSDTM":"2019-06-17 00:54:30","TRTEDTM":"2022-06-16 18:54:30","TRT01SDTM":"2019-06-17 00:54:30","TRT01EDTM":"2021-06-16 12:54:30","TRT02SDTM":"2021-06-16 12:54:30","TRT02EDTM":"2022-06-16 18:54:30","AP01SDTM":"2019-06-17 00:54:30","AP01EDTM":"2021-06-16 12:54:30","AP02SDTM":"2021-06-16 12:54:30","AP02EDTM":"2022-06-16 18:54:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-16","EOSDY":1096,"LSTALVDT":"2022-07-08","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7852,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97544,"AVALU":"g/L","BASE2":2.99382,"BASE":2.80342,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01838,"PCHG2":-0.61383,"CHG":0.17202,"PCHG":6.13615,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-26 00:54:30","ADY":985,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-386","SUBJID":"id-386","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.56042,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-18 12:55:21","TRTEDTM":"2022-02-15 02:38:35","TRT01SDTM":"2020-01-18 12:55:21","TRT01EDTM":"2021-02-14 20:38:35","TRT02SDTM":"2021-02-14 20:38:35","TRT02EDTM":"2022-02-15 02:38:35","AP01SDTM":"2020-01-18 12:55:21","AP01EDTM":"2021-02-14 20:38:35","AP02SDTM":"2021-02-14 20:38:35","AP02EDTM":"2022-02-15 02:38:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":759,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":797,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2526,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.19925,"AVALU":"U/L","BASE2":20.19925,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-18 12:55:21","ADY":31,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-386","SUBJID":"id-386","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.56042,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-18 12:55:21","TRTEDTM":"2022-02-15 02:38:35","TRT01SDTM":"2020-01-18 12:55:21","TRT01EDTM":"2021-02-14 20:38:35","TRT02SDTM":"2021-02-14 20:38:35","TRT02EDTM":"2022-02-15 02:38:35","AP01SDTM":"2020-01-18 12:55:21","AP01EDTM":"2021-02-14 20:38:35","AP02SDTM":"2021-02-14 20:38:35","AP02EDTM":"2022-02-15 02:38:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":759,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":797,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":385,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.91087,"AVALU":"U/L","BASE2":20.19925,"BASE":10.91087,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-9.28838,"PCHG2":-45.98378,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-13 12:55:21","ADY":86,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-386","SUBJID":"id-386","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.56042,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-18 12:55:21","TRTEDTM":"2022-02-15 02:38:35","TRT01SDTM":"2020-01-18 12:55:21","TRT01EDTM":"2021-02-14 20:38:35","TRT02SDTM":"2021-02-14 20:38:35","TRT02EDTM":"2022-02-15 02:38:35","AP01SDTM":"2020-01-18 12:55:21","AP01EDTM":"2021-02-14 20:38:35","AP02SDTM":"2021-02-14 20:38:35","AP02EDTM":"2022-02-15 02:38:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":759,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":797,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3305,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.77615,"AVALU":"U/L","BASE2":20.19925,"BASE":10.91087,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.5769,"PCHG2":32.56015,"CHG":15.86528,"PCHG":145.40804,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-11 12:55:21","ADY":145,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-386","SUBJID":"id-386","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.56042,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-18 12:55:21","TRTEDTM":"2022-02-15 02:38:35","TRT01SDTM":"2020-01-18 12:55:21","TRT01EDTM":"2021-02-14 20:38:35","TRT02SDTM":"2021-02-14 20:38:35","TRT02EDTM":"2022-02-15 02:38:35","AP01SDTM":"2020-01-18 12:55:21","AP01EDTM":"2021-02-14 20:38:35","AP02SDTM":"2021-02-14 20:38:35","AP02EDTM":"2022-02-15 02:38:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":759,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":797,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1610,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.54676,"AVALU":"U/L","BASE2":20.19925,"BASE":10.91087,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.34751,"PCHG2":36.37516,"CHG":16.63589,"PCHG":152.47076,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-01 12:55:21","ADY":288,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-386","SUBJID":"id-386","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.56042,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-18 12:55:21","TRTEDTM":"2022-02-15 02:38:35","TRT01SDTM":"2020-01-18 12:55:21","TRT01EDTM":"2021-02-14 20:38:35","TRT02SDTM":"2021-02-14 20:38:35","TRT02EDTM":"2022-02-15 02:38:35","AP01SDTM":"2020-01-18 12:55:21","AP01EDTM":"2021-02-14 20:38:35","AP02SDTM":"2021-02-14 20:38:35","AP02EDTM":"2022-02-15 02:38:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":759,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":797,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3454,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.23612,"AVALU":"U/L","BASE2":20.19925,"BASE":10.91087,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.96313,"PCHG2":-54.27492,"CHG":-1.67475,"PCHG":-15.34935,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-22 12:55:21","ADY":401,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-386","SUBJID":"id-386","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.56042,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-18 12:55:21","TRTEDTM":"2022-02-15 02:38:35","TRT01SDTM":"2020-01-18 12:55:21","TRT01EDTM":"2021-02-14 20:38:35","TRT02SDTM":"2021-02-14 20:38:35","TRT02EDTM":"2022-02-15 02:38:35","AP01SDTM":"2020-01-18 12:55:21","AP01EDTM":"2021-02-14 20:38:35","AP02SDTM":"2021-02-14 20:38:35","AP02EDTM":"2022-02-15 02:38:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":759,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":797,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3355,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.74908,"AVALU":"U/L","BASE2":20.19925,"BASE":10.91087,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.54983,"PCHG2":2.72203,"CHG":9.83821,"PCHG":90.16886,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-04 12:55:21","ADY":411,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-386","SUBJID":"id-386","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.56042,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-18 12:55:21","TRTEDTM":"2022-02-15 02:38:35","TRT01SDTM":"2020-01-18 12:55:21","TRT01EDTM":"2021-02-14 20:38:35","TRT02SDTM":"2021-02-14 20:38:35","TRT02EDTM":"2022-02-15 02:38:35","AP01SDTM":"2020-01-18 12:55:21","AP01EDTM":"2021-02-14 20:38:35","AP02SDTM":"2021-02-14 20:38:35","AP02EDTM":"2022-02-15 02:38:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":759,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":797,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7257,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.03027,"AVALU":"U/L","BASE2":20.19925,"BASE":10.91087,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.16897,"PCHG2":-5.78721,"CHG":8.1194,"PCHG":74.41574,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-30 12:55:21","ADY":468,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-386","SUBJID":"id-386","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.56042,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-18 12:55:21","TRTEDTM":"2022-02-15 02:38:35","TRT01SDTM":"2020-01-18 12:55:21","TRT01EDTM":"2021-02-14 20:38:35","TRT02SDTM":"2021-02-14 20:38:35","TRT02EDTM":"2022-02-15 02:38:35","AP01SDTM":"2020-01-18 12:55:21","AP01EDTM":"2021-02-14 20:38:35","AP02SDTM":"2021-02-14 20:38:35","AP02EDTM":"2022-02-15 02:38:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":759,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":797,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2750,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.12418,"AVALU":"mg/L","BASE2":9.12418,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-18 12:55:21","ADY":31,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-386","SUBJID":"id-386","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.56042,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-18 12:55:21","TRTEDTM":"2022-02-15 02:38:35","TRT01SDTM":"2020-01-18 12:55:21","TRT01EDTM":"2021-02-14 20:38:35","TRT02SDTM":"2021-02-14 20:38:35","TRT02EDTM":"2022-02-15 02:38:35","AP01SDTM":"2020-01-18 12:55:21","AP01EDTM":"2021-02-14 20:38:35","AP02SDTM":"2021-02-14 20:38:35","AP02EDTM":"2022-02-15 02:38:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":759,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":797,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5992,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.74995,"AVALU":"mg/L","BASE2":9.12418,"BASE":9.74995,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.62577,"PCHG2":6.85842,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-13 12:55:21","ADY":86,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-386","SUBJID":"id-386","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.56042,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-18 12:55:21","TRTEDTM":"2022-02-15 02:38:35","TRT01SDTM":"2020-01-18 12:55:21","TRT01EDTM":"2021-02-14 20:38:35","TRT02SDTM":"2021-02-14 20:38:35","TRT02EDTM":"2022-02-15 02:38:35","AP01SDTM":"2020-01-18 12:55:21","AP01EDTM":"2021-02-14 20:38:35","AP02SDTM":"2021-02-14 20:38:35","AP02EDTM":"2022-02-15 02:38:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":759,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":797,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7967,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.74763,"AVALU":"mg/L","BASE2":9.12418,"BASE":9.74995,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.62345,"PCHG2":17.79283,"CHG":0.99768,"PCHG":10.23262,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-06-11 12:55:21","ADY":145,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-386","SUBJID":"id-386","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.56042,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-18 12:55:21","TRTEDTM":"2022-02-15 02:38:35","TRT01SDTM":"2020-01-18 12:55:21","TRT01EDTM":"2021-02-14 20:38:35","TRT02SDTM":"2021-02-14 20:38:35","TRT02EDTM":"2022-02-15 02:38:35","AP01SDTM":"2020-01-18 12:55:21","AP01EDTM":"2021-02-14 20:38:35","AP02SDTM":"2021-02-14 20:38:35","AP02EDTM":"2022-02-15 02:38:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":759,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":797,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1009,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.97688,"AVALU":"mg/L","BASE2":9.12418,"BASE":9.74995,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1473,"PCHG2":-1.61439,"CHG":-0.77307,"PCHG":-7.92901,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-01 12:55:21","ADY":288,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-386","SUBJID":"id-386","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.56042,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-18 12:55:21","TRTEDTM":"2022-02-15 02:38:35","TRT01SDTM":"2020-01-18 12:55:21","TRT01EDTM":"2021-02-14 20:38:35","TRT02SDTM":"2021-02-14 20:38:35","TRT02EDTM":"2022-02-15 02:38:35","AP01SDTM":"2020-01-18 12:55:21","AP01EDTM":"2021-02-14 20:38:35","AP02SDTM":"2021-02-14 20:38:35","AP02EDTM":"2022-02-15 02:38:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":759,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":797,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7053,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.86763,"AVALU":"mg/L","BASE2":9.12418,"BASE":9.74995,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.25655,"PCHG2":-2.8118,"CHG":-0.88233,"PCHG":-9.04956,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-22 12:55:21","ADY":401,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-386","SUBJID":"id-386","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.56042,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-18 12:55:21","TRTEDTM":"2022-02-15 02:38:35","TRT01SDTM":"2020-01-18 12:55:21","TRT01EDTM":"2021-02-14 20:38:35","TRT02SDTM":"2021-02-14 20:38:35","TRT02EDTM":"2022-02-15 02:38:35","AP01SDTM":"2020-01-18 12:55:21","AP01EDTM":"2021-02-14 20:38:35","AP02SDTM":"2021-02-14 20:38:35","AP02EDTM":"2022-02-15 02:38:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":759,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":797,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3881,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.58412,"AVALU":"mg/L","BASE2":9.12418,"BASE":9.74995,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.45994,"PCHG2":5.04092,"CHG":-0.16583,"PCHG":-1.70084,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-04 12:55:21","ADY":411,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-386","SUBJID":"id-386","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.56042,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-18 12:55:21","TRTEDTM":"2022-02-15 02:38:35","TRT01SDTM":"2020-01-18 12:55:21","TRT01EDTM":"2021-02-14 20:38:35","TRT02SDTM":"2021-02-14 20:38:35","TRT02EDTM":"2022-02-15 02:38:35","AP01SDTM":"2020-01-18 12:55:21","AP01EDTM":"2021-02-14 20:38:35","AP02SDTM":"2021-02-14 20:38:35","AP02EDTM":"2022-02-15 02:38:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":759,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":797,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2807,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.5233,"AVALU":"mg/L","BASE2":9.12418,"BASE":9.74995,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.39912,"PCHG2":4.37433,"CHG":-0.22665,"PCHG":-2.32466,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-30 12:55:21","ADY":468,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-386","SUBJID":"id-386","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.56042,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-18 12:55:21","TRTEDTM":"2022-02-15 02:38:35","TRT01SDTM":"2020-01-18 12:55:21","TRT01EDTM":"2021-02-14 20:38:35","TRT02SDTM":"2021-02-14 20:38:35","TRT02EDTM":"2022-02-15 02:38:35","AP01SDTM":"2020-01-18 12:55:21","AP01EDTM":"2021-02-14 20:38:35","AP02SDTM":"2021-02-14 20:38:35","AP02EDTM":"2022-02-15 02:38:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":759,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":797,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4491,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00133,"AVALU":"g/L","BASE2":3.00133,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-02-18 12:55:21","ADY":31,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-386","SUBJID":"id-386","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.56042,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-18 12:55:21","TRTEDTM":"2022-02-15 02:38:35","TRT01SDTM":"2020-01-18 12:55:21","TRT01EDTM":"2021-02-14 20:38:35","TRT02SDTM":"2021-02-14 20:38:35","TRT02EDTM":"2022-02-15 02:38:35","AP01SDTM":"2020-01-18 12:55:21","AP01EDTM":"2021-02-14 20:38:35","AP02SDTM":"2021-02-14 20:38:35","AP02EDTM":"2022-02-15 02:38:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":759,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":797,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1760,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81721,"AVALU":"g/L","BASE2":3.00133,"BASE":2.81721,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.18411,"PCHG2":-6.13435,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-13 12:55:21","ADY":86,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-386","SUBJID":"id-386","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.56042,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-18 12:55:21","TRTEDTM":"2022-02-15 02:38:35","TRT01SDTM":"2020-01-18 12:55:21","TRT01EDTM":"2021-02-14 20:38:35","TRT02SDTM":"2021-02-14 20:38:35","TRT02EDTM":"2022-02-15 02:38:35","AP01SDTM":"2020-01-18 12:55:21","AP01EDTM":"2021-02-14 20:38:35","AP02SDTM":"2021-02-14 20:38:35","AP02EDTM":"2022-02-15 02:38:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":759,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":797,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":821,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.113,"AVALU":"g/L","BASE2":3.00133,"BASE":2.81721,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11168,"PCHG2":3.72097,"CHG":0.29579,"PCHG":10.49939,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-06-11 12:55:21","ADY":145,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-386","SUBJID":"id-386","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.56042,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-18 12:55:21","TRTEDTM":"2022-02-15 02:38:35","TRT01SDTM":"2020-01-18 12:55:21","TRT01EDTM":"2021-02-14 20:38:35","TRT02SDTM":"2021-02-14 20:38:35","TRT02EDTM":"2022-02-15 02:38:35","AP01SDTM":"2020-01-18 12:55:21","AP01EDTM":"2021-02-14 20:38:35","AP02SDTM":"2021-02-14 20:38:35","AP02EDTM":"2022-02-15 02:38:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":759,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":797,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7473,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96811,"AVALU":"g/L","BASE2":3.00133,"BASE":2.81721,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03322,"PCHG2":-1.10685,"CHG":0.15089,"PCHG":5.35606,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-01 12:55:21","ADY":288,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-386","SUBJID":"id-386","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.56042,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-18 12:55:21","TRTEDTM":"2022-02-15 02:38:35","TRT01SDTM":"2020-01-18 12:55:21","TRT01EDTM":"2021-02-14 20:38:35","TRT02SDTM":"2021-02-14 20:38:35","TRT02EDTM":"2022-02-15 02:38:35","AP01SDTM":"2020-01-18 12:55:21","AP01EDTM":"2021-02-14 20:38:35","AP02SDTM":"2021-02-14 20:38:35","AP02EDTM":"2022-02-15 02:38:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":759,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":797,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2131,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75702,"AVALU":"g/L","BASE2":3.00133,"BASE":2.81721,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.24431,"PCHG2":-8.14005,"CHG":-0.0602,"PCHG":-2.13678,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-22 12:55:21","ADY":401,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-386","SUBJID":"id-386","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.56042,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-18 12:55:21","TRTEDTM":"2022-02-15 02:38:35","TRT01SDTM":"2020-01-18 12:55:21","TRT01EDTM":"2021-02-14 20:38:35","TRT02SDTM":"2021-02-14 20:38:35","TRT02EDTM":"2022-02-15 02:38:35","AP01SDTM":"2020-01-18 12:55:21","AP01EDTM":"2021-02-14 20:38:35","AP02SDTM":"2021-02-14 20:38:35","AP02EDTM":"2022-02-15 02:38:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":759,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":797,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":171,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.63786,"AVALU":"g/L","BASE2":3.00133,"BASE":2.81721,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.36347,"PCHG2":-12.11022,"CHG":-0.17936,"PCHG":-6.36641,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-04 12:55:21","ADY":411,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-386","SUBJID":"id-386","SITEID":"CHN-11","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.56042,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-18 12:55:21","TRTEDTM":"2022-02-15 02:38:35","TRT01SDTM":"2020-01-18 12:55:21","TRT01EDTM":"2021-02-14 20:38:35","TRT02SDTM":"2021-02-14 20:38:35","TRT02EDTM":"2022-02-15 02:38:35","AP01SDTM":"2020-01-18 12:55:21","AP01EDTM":"2021-02-14 20:38:35","AP02SDTM":"2021-02-14 20:38:35","AP02EDTM":"2022-02-15 02:38:35","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":759,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":797,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1308,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91187,"AVALU":"g/L","BASE2":3.00133,"BASE":2.81721,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08945,"PCHG2":-2.98042,"CHG":0.09466,"PCHG":3.36005,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-30 12:55:21","ADY":468,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-391","SUBJID":"id-391","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.9676,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-12","TRTSDTM":"2020-05-15 21:08:17","TRTEDTM":"2022-02-19 11:03:33","TRT01SDTM":"2020-05-15 21:08:17","TRT01EDTM":"2021-02-19 05:03:33","TRT02SDTM":"2021-02-19 05:03:33","TRT02EDTM":"2022-02-19 11:03:33","AP01SDTM":"2020-05-15 21:08:17","AP01EDTM":"2021-02-19 05:03:33","AP02SDTM":"2021-02-19 05:03:33","AP02EDTM":"2022-02-19 11:03:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":645,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-03","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5319,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.52336,"AVALU":"U/L","BASE2":15.52336,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-17 21:08:17","ADY":186,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-391","SUBJID":"id-391","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.9676,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-12","TRTSDTM":"2020-05-15 21:08:17","TRTEDTM":"2022-02-19 11:03:33","TRT01SDTM":"2020-05-15 21:08:17","TRT01EDTM":"2021-02-19 05:03:33","TRT02SDTM":"2021-02-19 05:03:33","TRT02EDTM":"2022-02-19 11:03:33","AP01SDTM":"2020-05-15 21:08:17","AP01EDTM":"2021-02-19 05:03:33","AP02SDTM":"2021-02-19 05:03:33","AP02EDTM":"2022-02-19 11:03:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":645,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-03","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2393,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.47009,"AVALU":"U/L","BASE2":15.52336,"BASE":20.47009,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":4.94674,"PCHG2":31.86641,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-12 21:08:17","ADY":211,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-391","SUBJID":"id-391","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.9676,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-12","TRTSDTM":"2020-05-15 21:08:17","TRTEDTM":"2022-02-19 11:03:33","TRT01SDTM":"2020-05-15 21:08:17","TRT01EDTM":"2021-02-19 05:03:33","TRT02SDTM":"2021-02-19 05:03:33","TRT02EDTM":"2022-02-19 11:03:33","AP01SDTM":"2020-05-15 21:08:17","AP01EDTM":"2021-02-19 05:03:33","AP02SDTM":"2021-02-19 05:03:33","AP02EDTM":"2022-02-19 11:03:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":645,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-03","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8260,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.33546,"AVALU":"U/L","BASE2":15.52336,"BASE":20.47009,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.81211,"PCHG2":95.41819,"CHG":9.86537,"PCHG":48.19406,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-22 21:08:17","ADY":342,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-391","SUBJID":"id-391","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.9676,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-12","TRTSDTM":"2020-05-15 21:08:17","TRTEDTM":"2022-02-19 11:03:33","TRT01SDTM":"2020-05-15 21:08:17","TRT01EDTM":"2021-02-19 05:03:33","TRT02SDTM":"2021-02-19 05:03:33","TRT02EDTM":"2022-02-19 11:03:33","AP01SDTM":"2020-05-15 21:08:17","AP01EDTM":"2021-02-19 05:03:33","AP02SDTM":"2021-02-19 05:03:33","AP02EDTM":"2022-02-19 11:03:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":645,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-03","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3763,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.40891,"AVALU":"U/L","BASE2":15.52336,"BASE":20.47009,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.11445,"PCHG2":-7.17917,"CHG":-6.06118,"PCHG":-29.60995,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-13 21:08:17","ADY":394,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-391","SUBJID":"id-391","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.9676,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-12","TRTSDTM":"2020-05-15 21:08:17","TRTEDTM":"2022-02-19 11:03:33","TRT01SDTM":"2020-05-15 21:08:17","TRT01EDTM":"2021-02-19 05:03:33","TRT02SDTM":"2021-02-19 05:03:33","TRT02EDTM":"2022-02-19 11:03:33","AP01SDTM":"2020-05-15 21:08:17","AP01EDTM":"2021-02-19 05:03:33","AP02SDTM":"2021-02-19 05:03:33","AP02EDTM":"2022-02-19 11:03:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":645,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-03","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7019,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.5956,"AVALU":"U/L","BASE2":15.52336,"BASE":20.47009,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.07224,"PCHG2":6.90728,"CHG":-3.8745,"PCHG":-18.92759,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-28 21:08:17","ADY":409,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-391","SUBJID":"id-391","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.9676,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-12","TRTSDTM":"2020-05-15 21:08:17","TRTEDTM":"2022-02-19 11:03:33","TRT01SDTM":"2020-05-15 21:08:17","TRT01EDTM":"2021-02-19 05:03:33","TRT02SDTM":"2021-02-19 05:03:33","TRT02EDTM":"2022-02-19 11:03:33","AP01SDTM":"2020-05-15 21:08:17","AP01EDTM":"2021-02-19 05:03:33","AP02SDTM":"2021-02-19 05:03:33","AP02EDTM":"2022-02-19 11:03:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":645,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-03","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1788,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.93436,"AVALU":"U/L","BASE2":15.52336,"BASE":20.47009,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.58899,"PCHG2":-10.23614,"CHG":-6.53573,"PCHG":-31.92818,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-27 21:08:17","ADY":561,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-391","SUBJID":"id-391","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.9676,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-12","TRTSDTM":"2020-05-15 21:08:17","TRTEDTM":"2022-02-19 11:03:33","TRT01SDTM":"2020-05-15 21:08:17","TRT01EDTM":"2021-02-19 05:03:33","TRT02SDTM":"2021-02-19 05:03:33","TRT02EDTM":"2022-02-19 11:03:33","AP01SDTM":"2020-05-15 21:08:17","AP01EDTM":"2021-02-19 05:03:33","AP02SDTM":"2021-02-19 05:03:33","AP02EDTM":"2022-02-19 11:03:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":645,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-03","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7819,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.65425,"AVALU":"U/L","BASE2":15.52336,"BASE":20.47009,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.86911,"PCHG2":-18.48254,"CHG":-7.81585,"PCHG":-38.18179,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-09 21:08:17","ADY":635,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-391","SUBJID":"id-391","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.9676,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-12","TRTSDTM":"2020-05-15 21:08:17","TRTEDTM":"2022-02-19 11:03:33","TRT01SDTM":"2020-05-15 21:08:17","TRT01EDTM":"2021-02-19 05:03:33","TRT02SDTM":"2021-02-19 05:03:33","TRT02EDTM":"2022-02-19 11:03:33","AP01SDTM":"2020-05-15 21:08:17","AP01EDTM":"2021-02-19 05:03:33","AP02SDTM":"2021-02-19 05:03:33","AP02EDTM":"2022-02-19 11:03:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":645,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-03","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7107,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.26843,"AVALU":"mg/L","BASE2":9.26843,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-17 21:08:17","ADY":186,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-391","SUBJID":"id-391","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.9676,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-12","TRTSDTM":"2020-05-15 21:08:17","TRTEDTM":"2022-02-19 11:03:33","TRT01SDTM":"2020-05-15 21:08:17","TRT01EDTM":"2021-02-19 05:03:33","TRT02SDTM":"2021-02-19 05:03:33","TRT02EDTM":"2022-02-19 11:03:33","AP01SDTM":"2020-05-15 21:08:17","AP01EDTM":"2021-02-19 05:03:33","AP02SDTM":"2021-02-19 05:03:33","AP02EDTM":"2022-02-19 11:03:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":645,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-03","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5433,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.75447,"AVALU":"mg/L","BASE2":9.26843,"BASE":8.75447,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.51397,"PCHG2":-5.54533,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-12 21:08:17","ADY":211,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-391","SUBJID":"id-391","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.9676,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-12","TRTSDTM":"2020-05-15 21:08:17","TRTEDTM":"2022-02-19 11:03:33","TRT01SDTM":"2020-05-15 21:08:17","TRT01EDTM":"2021-02-19 05:03:33","TRT02SDTM":"2021-02-19 05:03:33","TRT02EDTM":"2022-02-19 11:03:33","AP01SDTM":"2020-05-15 21:08:17","AP01EDTM":"2021-02-19 05:03:33","AP02SDTM":"2021-02-19 05:03:33","AP02EDTM":"2022-02-19 11:03:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":645,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-03","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2197,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.65126,"AVALU":"mg/L","BASE2":9.26843,"BASE":8.75447,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.61718,"PCHG2":-6.65891,"CHG":-0.10321,"PCHG":-1.17896,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-22 21:08:17","ADY":342,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-391","SUBJID":"id-391","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.9676,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-12","TRTSDTM":"2020-05-15 21:08:17","TRTEDTM":"2022-02-19 11:03:33","TRT01SDTM":"2020-05-15 21:08:17","TRT01EDTM":"2021-02-19 05:03:33","TRT02SDTM":"2021-02-19 05:03:33","TRT02EDTM":"2022-02-19 11:03:33","AP01SDTM":"2020-05-15 21:08:17","AP01EDTM":"2021-02-19 05:03:33","AP02SDTM":"2021-02-19 05:03:33","AP02EDTM":"2022-02-19 11:03:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":645,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-03","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2965,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.95742,"AVALU":"mg/L","BASE2":9.26843,"BASE":8.75447,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.31101,"PCHG2":-14.14493,"CHG":-0.79705,"PCHG":-9.10447,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-06-13 21:08:17","ADY":394,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-391","SUBJID":"id-391","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.9676,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-12","TRTSDTM":"2020-05-15 21:08:17","TRTEDTM":"2022-02-19 11:03:33","TRT01SDTM":"2020-05-15 21:08:17","TRT01EDTM":"2021-02-19 05:03:33","TRT02SDTM":"2021-02-19 05:03:33","TRT02EDTM":"2022-02-19 11:03:33","AP01SDTM":"2020-05-15 21:08:17","AP01EDTM":"2021-02-19 05:03:33","AP02SDTM":"2021-02-19 05:03:33","AP02EDTM":"2022-02-19 11:03:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":645,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-03","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4098,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.93562,"AVALU":"mg/L","BASE2":9.26843,"BASE":8.75447,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.33281,"PCHG2":-3.59079,"CHG":0.18116,"PCHG":2.06929,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-28 21:08:17","ADY":409,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-391","SUBJID":"id-391","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.9676,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-12","TRTSDTM":"2020-05-15 21:08:17","TRTEDTM":"2022-02-19 11:03:33","TRT01SDTM":"2020-05-15 21:08:17","TRT01EDTM":"2021-02-19 05:03:33","TRT02SDTM":"2021-02-19 05:03:33","TRT02EDTM":"2022-02-19 11:03:33","AP01SDTM":"2020-05-15 21:08:17","AP01EDTM":"2021-02-19 05:03:33","AP02SDTM":"2021-02-19 05:03:33","AP02EDTM":"2022-02-19 11:03:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":645,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-03","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7855,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.52983,"AVALU":"mg/L","BASE2":9.26843,"BASE":8.75447,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.26139,"PCHG2":2.82025,"CHG":0.77536,"PCHG":8.85671,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-27 21:08:17","ADY":561,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-391","SUBJID":"id-391","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.9676,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-12","TRTSDTM":"2020-05-15 21:08:17","TRTEDTM":"2022-02-19 11:03:33","TRT01SDTM":"2020-05-15 21:08:17","TRT01EDTM":"2021-02-19 05:03:33","TRT02SDTM":"2021-02-19 05:03:33","TRT02EDTM":"2022-02-19 11:03:33","AP01SDTM":"2020-05-15 21:08:17","AP01EDTM":"2021-02-19 05:03:33","AP02SDTM":"2021-02-19 05:03:33","AP02EDTM":"2022-02-19 11:03:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":645,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-03","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2559,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.40735,"AVALU":"mg/L","BASE2":9.26843,"BASE":8.75447,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13891,"PCHG2":1.49878,"CHG":0.65288,"PCHG":7.45767,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-09 21:08:17","ADY":635,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-391","SUBJID":"id-391","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.9676,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-12","TRTSDTM":"2020-05-15 21:08:17","TRTEDTM":"2022-02-19 11:03:33","TRT01SDTM":"2020-05-15 21:08:17","TRT01EDTM":"2021-02-19 05:03:33","TRT02SDTM":"2021-02-19 05:03:33","TRT02EDTM":"2022-02-19 11:03:33","AP01SDTM":"2020-05-15 21:08:17","AP01EDTM":"2021-02-19 05:03:33","AP02SDTM":"2021-02-19 05:03:33","AP02EDTM":"2022-02-19 11:03:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":645,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-03","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5935,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03148,"AVALU":"g/L","BASE2":3.03148,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"4","BTOXGR":"1","ADTM":"2020-11-17 21:08:17","ADY":186,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-391","SUBJID":"id-391","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.9676,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-12","TRTSDTM":"2020-05-15 21:08:17","TRTEDTM":"2022-02-19 11:03:33","TRT01SDTM":"2020-05-15 21:08:17","TRT01EDTM":"2021-02-19 05:03:33","TRT02SDTM":"2021-02-19 05:03:33","TRT02EDTM":"2022-02-19 11:03:33","AP01SDTM":"2020-05-15 21:08:17","AP01EDTM":"2021-02-19 05:03:33","AP02SDTM":"2021-02-19 05:03:33","AP02EDTM":"2022-02-19 11:03:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":645,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-03","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1835,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01591,"AVALU":"g/L","BASE2":3.03148,"BASE":3.01591,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.01557,"PCHG2":-0.51361,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-12-12 21:08:17","ADY":211,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-391","SUBJID":"id-391","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.9676,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-12","TRTSDTM":"2020-05-15 21:08:17","TRTEDTM":"2022-02-19 11:03:33","TRT01SDTM":"2020-05-15 21:08:17","TRT01EDTM":"2021-02-19 05:03:33","TRT02SDTM":"2021-02-19 05:03:33","TRT02EDTM":"2022-02-19 11:03:33","AP01SDTM":"2020-05-15 21:08:17","AP01EDTM":"2021-02-19 05:03:33","AP02SDTM":"2021-02-19 05:03:33","AP02EDTM":"2022-02-19 11:03:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":645,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-03","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4072,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76844,"AVALU":"g/L","BASE2":3.03148,"BASE":3.01591,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.26304,"PCHG2":-8.67695,"CHG":-0.24747,"PCHG":-8.20548,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-04-22 21:08:17","ADY":342,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-391","SUBJID":"id-391","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.9676,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-12","TRTSDTM":"2020-05-15 21:08:17","TRTEDTM":"2022-02-19 11:03:33","TRT01SDTM":"2020-05-15 21:08:17","TRT01EDTM":"2021-02-19 05:03:33","TRT02SDTM":"2021-02-19 05:03:33","TRT02EDTM":"2022-02-19 11:03:33","AP01SDTM":"2020-05-15 21:08:17","AP01EDTM":"2021-02-19 05:03:33","AP02SDTM":"2021-02-19 05:03:33","AP02EDTM":"2022-02-19 11:03:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":645,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-03","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3070,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99448,"AVALU":"g/L","BASE2":3.03148,"BASE":3.01591,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.037,"PCHG2":-1.22064,"CHG":-0.02143,"PCHG":-0.71068,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-06-13 21:08:17","ADY":394,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-391","SUBJID":"id-391","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.9676,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-12","TRTSDTM":"2020-05-15 21:08:17","TRTEDTM":"2022-02-19 11:03:33","TRT01SDTM":"2020-05-15 21:08:17","TRT01EDTM":"2021-02-19 05:03:33","TRT02SDTM":"2021-02-19 05:03:33","TRT02EDTM":"2022-02-19 11:03:33","AP01SDTM":"2020-05-15 21:08:17","AP01EDTM":"2021-02-19 05:03:33","AP02SDTM":"2021-02-19 05:03:33","AP02EDTM":"2022-02-19 11:03:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":645,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-03","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1086,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96491,"AVALU":"g/L","BASE2":3.03148,"BASE":3.01591,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06657,"PCHG2":-2.19602,"CHG":-0.051,"PCHG":-1.69109,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-06-28 21:08:17","ADY":409,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-391","SUBJID":"id-391","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.9676,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-12","TRTSDTM":"2020-05-15 21:08:17","TRTEDTM":"2022-02-19 11:03:33","TRT01SDTM":"2020-05-15 21:08:17","TRT01EDTM":"2021-02-19 05:03:33","TRT02SDTM":"2021-02-19 05:03:33","TRT02EDTM":"2022-02-19 11:03:33","AP01SDTM":"2020-05-15 21:08:17","AP01EDTM":"2021-02-19 05:03:33","AP02SDTM":"2021-02-19 05:03:33","AP02EDTM":"2022-02-19 11:03:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":645,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-03","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7847,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85837,"AVALU":"g/L","BASE2":3.03148,"BASE":3.01591,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17312,"PCHG2":-5.71068,"CHG":-0.15755,"PCHG":-5.2239,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-11-27 21:08:17","ADY":561,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-391","SUBJID":"id-391","SITEID":"CHN-11","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.9676,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-12","TRTSDTM":"2020-05-15 21:08:17","TRTEDTM":"2022-02-19 11:03:33","TRT01SDTM":"2020-05-15 21:08:17","TRT01EDTM":"2021-02-19 05:03:33","TRT02SDTM":"2021-02-19 05:03:33","TRT02EDTM":"2022-02-19 11:03:33","AP01SDTM":"2020-05-15 21:08:17","AP01EDTM":"2021-02-19 05:03:33","AP02SDTM":"2021-02-19 05:03:33","AP02EDTM":"2022-02-19 11:03:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":645,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-03","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6054,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81181,"AVALU":"g/L","BASE2":3.03148,"BASE":3.01591,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21967,"PCHG2":-7.24633,"CHG":-0.2041,"PCHG":-6.76748,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2022-02-09 21:08:17","ADY":635,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-392","SUBJID":"id-392","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.77395,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-24","TRTSDTM":"2019-09-28 10:00:27","TRT01SDTM":"2019-09-28 10:00:27","AP01SDTM":"2019-09-28 10:00:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":456,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.10174,"AVALU":"U/L","BASE2":27.10174,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-04 10:00:27","ADY":67,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-392","SUBJID":"id-392","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.77395,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-24","TRTSDTM":"2019-09-28 10:00:27","TRT01SDTM":"2019-09-28 10:00:27","AP01SDTM":"2019-09-28 10:00:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1691,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.26228,"AVALU":"U/L","BASE2":27.10174,"BASE":7.26228,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-19.83947,"PCHG2":-73.20366,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-22 10:00:27","ADY":176,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-392","SUBJID":"id-392","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.77395,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-24","TRTSDTM":"2019-09-28 10:00:27","TRT01SDTM":"2019-09-28 10:00:27","AP01SDTM":"2019-09-28 10:00:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7217,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.74244,"AVALU":"U/L","BASE2":27.10174,"BASE":7.26228,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-18.3593,"PCHG2":-67.74214,"CHG":1.48017,"PCHG":20.38159,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-02 10:00:27","ADY":248,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-392","SUBJID":"id-392","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.77395,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-24","TRTSDTM":"2019-09-28 10:00:27","TRT01SDTM":"2019-09-28 10:00:27","AP01SDTM":"2019-09-28 10:00:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2430,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.82305,"AVALU":"U/L","BASE2":27.10174,"BASE":7.26228,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.72131,"PCHG2":2.66147,"CHG":20.56077,"PCHG":283.11747,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-27 10:00:27","ADY":334,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-392","SUBJID":"id-392","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.77395,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-24","TRTSDTM":"2019-09-28 10:00:27","TRT01SDTM":"2019-09-28 10:00:27","AP01SDTM":"2019-09-28 10:00:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":893,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.81742,"AVALU":"U/L","BASE2":27.10174,"BASE":7.26228,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.28432,"PCHG2":-12.11848,"CHG":16.55515,"PCHG":227.96085,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-26 10:00:27","ADY":576,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-392","SUBJID":"id-392","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.77395,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-24","TRTSDTM":"2019-09-28 10:00:27","TRT01SDTM":"2019-09-28 10:00:27","AP01SDTM":"2019-09-28 10:00:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3566,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":54.24361,"AVALU":"U/L","BASE2":27.10174,"BASE":7.26228,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":27.14187,"PCHG2":100.14807,"CHG":46.98134,"PCHG":646.92306,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-01 10:00:27","ADY":581,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-392","SUBJID":"id-392","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.77395,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-24","TRTSDTM":"2019-09-28 10:00:27","TRT01SDTM":"2019-09-28 10:00:27","AP01SDTM":"2019-09-28 10:00:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3206,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.34278,"AVALU":"U/L","BASE2":27.10174,"BASE":7.26228,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.24104,"PCHG2":0.88939,"CHG":20.08051,"PCHG":276.50431,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-12 10:00:27","ADY":684,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-392","SUBJID":"id-392","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.77395,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-24","TRTSDTM":"2019-09-28 10:00:27","TRT01SDTM":"2019-09-28 10:00:27","AP01SDTM":"2019-09-28 10:00:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1613,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.62089,"AVALU":"mg/L","BASE2":8.62089,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-04 10:00:27","ADY":67,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-392","SUBJID":"id-392","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.77395,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-24","TRTSDTM":"2019-09-28 10:00:27","TRT01SDTM":"2019-09-28 10:00:27","AP01SDTM":"2019-09-28 10:00:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":728,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.25076,"AVALU":"mg/L","BASE2":8.62089,"BASE":9.25076,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.62987,"PCHG2":7.30635,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-22 10:00:27","ADY":176,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-392","SUBJID":"id-392","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.77395,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-24","TRTSDTM":"2019-09-28 10:00:27","TRT01SDTM":"2019-09-28 10:00:27","AP01SDTM":"2019-09-28 10:00:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":939,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.03322,"AVALU":"mg/L","BASE2":8.62089,"BASE":9.25076,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.58767,"PCHG2":-6.81682,"CHG":-1.21754,"PCHG":-13.16154,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-02 10:00:27","ADY":248,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-392","SUBJID":"id-392","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.77395,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-24","TRTSDTM":"2019-09-28 10:00:27","TRT01SDTM":"2019-09-28 10:00:27","AP01SDTM":"2019-09-28 10:00:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5159,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.56485,"AVALU":"mg/L","BASE2":8.62089,"BASE":9.25076,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05604,"PCHG2":-0.65009,"CHG":-0.68592,"PCHG":-7.4147,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-27 10:00:27","ADY":334,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-392","SUBJID":"id-392","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.77395,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-24","TRTSDTM":"2019-09-28 10:00:27","TRT01SDTM":"2019-09-28 10:00:27","AP01SDTM":"2019-09-28 10:00:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":39,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.07136,"AVALU":"mg/L","BASE2":8.62089,"BASE":9.25076,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.45047,"PCHG2":5.22532,"CHG":-0.1794,"PCHG":-1.93934,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-26 10:00:27","ADY":576,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-392","SUBJID":"id-392","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.77395,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-24","TRTSDTM":"2019-09-28 10:00:27","TRT01SDTM":"2019-09-28 10:00:27","AP01SDTM":"2019-09-28 10:00:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5559,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.5826,"AVALU":"mg/L","BASE2":8.62089,"BASE":9.25076,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03829,"PCHG2":-0.44417,"CHG":-0.66816,"PCHG":-7.2228,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-01 10:00:27","ADY":581,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-392","SUBJID":"id-392","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.77395,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-24","TRTSDTM":"2019-09-28 10:00:27","TRT01SDTM":"2019-09-28 10:00:27","AP01SDTM":"2019-09-28 10:00:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1594,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.94847,"AVALU":"mg/L","BASE2":8.62089,"BASE":9.25076,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.32758,"PCHG2":3.79986,"CHG":-0.30229,"PCHG":-3.26774,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-12 10:00:27","ADY":684,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-392","SUBJID":"id-392","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.77395,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-24","TRTSDTM":"2019-09-28 10:00:27","TRT01SDTM":"2019-09-28 10:00:27","AP01SDTM":"2019-09-28 10:00:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4332,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85887,"AVALU":"g/L","BASE2":2.85887,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-04 10:00:27","ADY":67,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-392","SUBJID":"id-392","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.77395,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-24","TRTSDTM":"2019-09-28 10:00:27","TRT01SDTM":"2019-09-28 10:00:27","AP01SDTM":"2019-09-28 10:00:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4556,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93701,"AVALU":"g/L","BASE2":2.85887,"BASE":2.93701,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.07815,"PCHG2":2.73354,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-22 10:00:27","ADY":176,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-392","SUBJID":"id-392","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.77395,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-24","TRTSDTM":"2019-09-28 10:00:27","TRT01SDTM":"2019-09-28 10:00:27","AP01SDTM":"2019-09-28 10:00:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":146,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83349,"AVALU":"g/L","BASE2":2.85887,"BASE":2.93701,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02537,"PCHG2":-0.88745,"CHG":-0.10352,"PCHG":-3.52464,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-02 10:00:27","ADY":248,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-392","SUBJID":"id-392","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.77395,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-24","TRTSDTM":"2019-09-28 10:00:27","TRT01SDTM":"2019-09-28 10:00:27","AP01SDTM":"2019-09-28 10:00:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4711,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99055,"AVALU":"g/L","BASE2":2.85887,"BASE":2.93701,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13168,"PCHG2":4.60611,"CHG":0.05353,"PCHG":1.82275,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-27 10:00:27","ADY":334,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-392","SUBJID":"id-392","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.77395,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-24","TRTSDTM":"2019-09-28 10:00:27","TRT01SDTM":"2019-09-28 10:00:27","AP01SDTM":"2019-09-28 10:00:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7755,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97977,"AVALU":"g/L","BASE2":2.85887,"BASE":2.93701,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1209,"PCHG2":4.22898,"CHG":0.04275,"PCHG":1.45565,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-26 10:00:27","ADY":576,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-392","SUBJID":"id-392","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.77395,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-24","TRTSDTM":"2019-09-28 10:00:27","TRT01SDTM":"2019-09-28 10:00:27","AP01SDTM":"2019-09-28 10:00:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4850,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86977,"AVALU":"g/L","BASE2":2.85887,"BASE":2.93701,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0109,"PCHG2":0.38143,"CHG":-0.06724,"PCHG":-2.28952,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-01 10:00:27","ADY":581,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-392","SUBJID":"id-392","SITEID":"CHN-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.77395,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-24","TRTSDTM":"2019-09-28 10:00:27","TRT01SDTM":"2019-09-28 10:00:27","AP01SDTM":"2019-09-28 10:00:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1797,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93122,"AVALU":"g/L","BASE2":2.85887,"BASE":2.93701,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07235,"PCHG2":2.53087,"CHG":-0.00579,"PCHG":-0.19727,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-12 10:00:27","ADY":684,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-54","SUBJID":"id-54","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.81516,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-17","TRTSDTM":"2019-08-21 06:30:41","TRTEDTM":"2022-08-21 00:30:41","TRT01SDTM":"2019-08-21 06:30:41","TRT01EDTM":"2021-08-20 18:30:41","TRT02SDTM":"2021-08-20 18:30:41","TRT02EDTM":"2022-08-21 00:30:41","AP01SDTM":"2019-08-21 06:30:41","AP01EDTM":"2021-08-20 18:30:41","AP02SDTM":"2021-08-20 18:30:41","AP02EDTM":"2022-08-21 00:30:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-21","EOSDY":1096,"LSTALVDT":"2022-09-01","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5925,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.3295,"AVALU":"U/L","BASE2":21.3295,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-09 06:30:41","ADY":262,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-54","SUBJID":"id-54","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.81516,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-17","TRTSDTM":"2019-08-21 06:30:41","TRTEDTM":"2022-08-21 00:30:41","TRT01SDTM":"2019-08-21 06:30:41","TRT01EDTM":"2021-08-20 18:30:41","TRT02SDTM":"2021-08-20 18:30:41","TRT02EDTM":"2022-08-21 00:30:41","AP01SDTM":"2019-08-21 06:30:41","AP01EDTM":"2021-08-20 18:30:41","AP02SDTM":"2021-08-20 18:30:41","AP02EDTM":"2022-08-21 00:30:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-21","EOSDY":1096,"LSTALVDT":"2022-09-01","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6149,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.92122,"AVALU":"U/L","BASE2":21.3295,"BASE":16.92122,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-4.40828,"PCHG2":-20.66753,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-12 06:30:41","ADY":265,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-54","SUBJID":"id-54","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.81516,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-17","TRTSDTM":"2019-08-21 06:30:41","TRTEDTM":"2022-08-21 00:30:41","TRT01SDTM":"2019-08-21 06:30:41","TRT01EDTM":"2021-08-20 18:30:41","TRT02SDTM":"2021-08-20 18:30:41","TRT02EDTM":"2022-08-21 00:30:41","AP01SDTM":"2019-08-21 06:30:41","AP01EDTM":"2021-08-20 18:30:41","AP02SDTM":"2021-08-20 18:30:41","AP02EDTM":"2022-08-21 00:30:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-21","EOSDY":1096,"LSTALVDT":"2022-09-01","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1527,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.65649,"AVALU":"U/L","BASE2":21.3295,"BASE":16.92122,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.32698,"PCHG2":62.48144,"CHG":17.73526,"PCHG":104.81077,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-04 06:30:41","ADY":349,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-54","SUBJID":"id-54","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.81516,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-17","TRTSDTM":"2019-08-21 06:30:41","TRTEDTM":"2022-08-21 00:30:41","TRT01SDTM":"2019-08-21 06:30:41","TRT01EDTM":"2021-08-20 18:30:41","TRT02SDTM":"2021-08-20 18:30:41","TRT02EDTM":"2022-08-21 00:30:41","AP01SDTM":"2019-08-21 06:30:41","AP01EDTM":"2021-08-20 18:30:41","AP02SDTM":"2021-08-20 18:30:41","AP02EDTM":"2022-08-21 00:30:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-21","EOSDY":1096,"LSTALVDT":"2022-09-01","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2158,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.47031,"AVALU":"U/L","BASE2":21.3295,"BASE":16.92122,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.85919,"PCHG2":-8.71653,"CHG":2.54909,"PCHG":15.06445,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-19 06:30:41","ADY":364,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-54","SUBJID":"id-54","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.81516,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-17","TRTSDTM":"2019-08-21 06:30:41","TRTEDTM":"2022-08-21 00:30:41","TRT01SDTM":"2019-08-21 06:30:41","TRT01EDTM":"2021-08-20 18:30:41","TRT02SDTM":"2021-08-20 18:30:41","TRT02EDTM":"2022-08-21 00:30:41","AP01SDTM":"2019-08-21 06:30:41","AP01EDTM":"2021-08-20 18:30:41","AP02SDTM":"2021-08-20 18:30:41","AP02EDTM":"2022-08-21 00:30:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-21","EOSDY":1096,"LSTALVDT":"2022-09-01","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6445,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.80058,"AVALU":"U/L","BASE2":21.3295,"BASE":16.92122,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.52892,"PCHG2":-30.6098,"CHG":-2.12064,"PCHG":-12.53241,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-24 06:30:41","ADY":826,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-54","SUBJID":"id-54","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.81516,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-17","TRTSDTM":"2019-08-21 06:30:41","TRTEDTM":"2022-08-21 00:30:41","TRT01SDTM":"2019-08-21 06:30:41","TRT01EDTM":"2021-08-20 18:30:41","TRT02SDTM":"2021-08-20 18:30:41","TRT02EDTM":"2022-08-21 00:30:41","AP01SDTM":"2019-08-21 06:30:41","AP01EDTM":"2021-08-20 18:30:41","AP02SDTM":"2021-08-20 18:30:41","AP02EDTM":"2022-08-21 00:30:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-21","EOSDY":1096,"LSTALVDT":"2022-09-01","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8194,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.35697,"AVALU":"U/L","BASE2":21.3295,"BASE":16.92122,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.97253,"PCHG2":-23.31292,"CHG":-0.56425,"PCHG":-3.33456,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-07 06:30:41","ADY":929,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-54","SUBJID":"id-54","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.81516,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-17","TRTSDTM":"2019-08-21 06:30:41","TRTEDTM":"2022-08-21 00:30:41","TRT01SDTM":"2019-08-21 06:30:41","TRT01EDTM":"2021-08-20 18:30:41","TRT02SDTM":"2021-08-20 18:30:41","TRT02EDTM":"2022-08-21 00:30:41","AP01SDTM":"2019-08-21 06:30:41","AP01EDTM":"2021-08-20 18:30:41","AP02SDTM":"2021-08-20 18:30:41","AP02EDTM":"2022-08-21 00:30:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-21","EOSDY":1096,"LSTALVDT":"2022-09-01","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":434,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.2647,"AVALU":"U/L","BASE2":21.3295,"BASE":16.92122,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.0648,"PCHG2":-47.18722,"CHG":-5.65652,"PCHG":-33.42854,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-18 06:30:41","ADY":1062,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-54","SUBJID":"id-54","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.81516,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-17","TRTSDTM":"2019-08-21 06:30:41","TRTEDTM":"2022-08-21 00:30:41","TRT01SDTM":"2019-08-21 06:30:41","TRT01EDTM":"2021-08-20 18:30:41","TRT02SDTM":"2021-08-20 18:30:41","TRT02EDTM":"2022-08-21 00:30:41","AP01SDTM":"2019-08-21 06:30:41","AP01EDTM":"2021-08-20 18:30:41","AP02SDTM":"2021-08-20 18:30:41","AP02EDTM":"2022-08-21 00:30:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-21","EOSDY":1096,"LSTALVDT":"2022-09-01","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8307,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.21107,"AVALU":"mg/L","BASE2":9.21107,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-05-09 06:30:41","ADY":262,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-54","SUBJID":"id-54","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.81516,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-17","TRTSDTM":"2019-08-21 06:30:41","TRTEDTM":"2022-08-21 00:30:41","TRT01SDTM":"2019-08-21 06:30:41","TRT01EDTM":"2021-08-20 18:30:41","TRT02SDTM":"2021-08-20 18:30:41","TRT02EDTM":"2022-08-21 00:30:41","AP01SDTM":"2019-08-21 06:30:41","AP01EDTM":"2021-08-20 18:30:41","AP02SDTM":"2021-08-20 18:30:41","AP02EDTM":"2022-08-21 00:30:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-21","EOSDY":1096,"LSTALVDT":"2022-09-01","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2132,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.04382,"AVALU":"mg/L","BASE2":9.21107,"BASE":10.04382,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.83276,"PCHG2":9.04084,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-05-12 06:30:41","ADY":265,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-54","SUBJID":"id-54","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.81516,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-17","TRTSDTM":"2019-08-21 06:30:41","TRTEDTM":"2022-08-21 00:30:41","TRT01SDTM":"2019-08-21 06:30:41","TRT01EDTM":"2021-08-20 18:30:41","TRT02SDTM":"2021-08-20 18:30:41","TRT02EDTM":"2022-08-21 00:30:41","AP01SDTM":"2019-08-21 06:30:41","AP01EDTM":"2021-08-20 18:30:41","AP02SDTM":"2021-08-20 18:30:41","AP02EDTM":"2022-08-21 00:30:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-21","EOSDY":1096,"LSTALVDT":"2022-09-01","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1858,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.87694,"AVALU":"mg/L","BASE2":9.21107,"BASE":10.04382,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.33413,"PCHG2":-14.48399,"CHG":-2.16689,"PCHG":-21.57433,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-1","BTOXGR":"1","ADTM":"2020-08-04 06:30:41","ADY":349,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-54","SUBJID":"id-54","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.81516,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-17","TRTSDTM":"2019-08-21 06:30:41","TRTEDTM":"2022-08-21 00:30:41","TRT01SDTM":"2019-08-21 06:30:41","TRT01EDTM":"2021-08-20 18:30:41","TRT02SDTM":"2021-08-20 18:30:41","TRT02EDTM":"2022-08-21 00:30:41","AP01SDTM":"2019-08-21 06:30:41","AP01EDTM":"2021-08-20 18:30:41","AP02SDTM":"2021-08-20 18:30:41","AP02EDTM":"2022-08-21 00:30:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-21","EOSDY":1096,"LSTALVDT":"2022-09-01","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5161,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.75337,"AVALU":"mg/L","BASE2":9.21107,"BASE":10.04382,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.5423,"PCHG2":16.74404,"CHG":0.70955,"PCHG":7.0645,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"4","BTOXGR":"1","ADTM":"2020-08-19 06:30:41","ADY":364,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-54","SUBJID":"id-54","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.81516,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-17","TRTSDTM":"2019-08-21 06:30:41","TRTEDTM":"2022-08-21 00:30:41","TRT01SDTM":"2019-08-21 06:30:41","TRT01EDTM":"2021-08-20 18:30:41","TRT02SDTM":"2021-08-20 18:30:41","TRT02EDTM":"2022-08-21 00:30:41","AP01SDTM":"2019-08-21 06:30:41","AP01EDTM":"2021-08-20 18:30:41","AP02SDTM":"2021-08-20 18:30:41","AP02EDTM":"2022-08-21 00:30:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-21","EOSDY":1096,"LSTALVDT":"2022-09-01","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5236,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.78065,"AVALU":"mg/L","BASE2":9.21107,"BASE":10.04382,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.43042,"PCHG2":-4.67284,"CHG":-1.26318,"PCHG":-12.57665,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-11-24 06:30:41","ADY":826,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-54","SUBJID":"id-54","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.81516,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-17","TRTSDTM":"2019-08-21 06:30:41","TRTEDTM":"2022-08-21 00:30:41","TRT01SDTM":"2019-08-21 06:30:41","TRT01EDTM":"2021-08-20 18:30:41","TRT02SDTM":"2021-08-20 18:30:41","TRT02EDTM":"2022-08-21 00:30:41","AP01SDTM":"2019-08-21 06:30:41","AP01EDTM":"2021-08-20 18:30:41","AP02SDTM":"2021-08-20 18:30:41","AP02EDTM":"2022-08-21 00:30:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-21","EOSDY":1096,"LSTALVDT":"2022-09-01","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4392,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.12626,"AVALU":"mg/L","BASE2":9.21107,"BASE":10.04382,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.9152,"PCHG2":9.93584,"CHG":0.08244,"PCHG":0.82079,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"3","BTOXGR":"1","ADTM":"2022-03-07 06:30:41","ADY":929,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-54","SUBJID":"id-54","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.81516,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-17","TRTSDTM":"2019-08-21 06:30:41","TRTEDTM":"2022-08-21 00:30:41","TRT01SDTM":"2019-08-21 06:30:41","TRT01EDTM":"2021-08-20 18:30:41","TRT02SDTM":"2021-08-20 18:30:41","TRT02EDTM":"2022-08-21 00:30:41","AP01SDTM":"2019-08-21 06:30:41","AP01EDTM":"2021-08-20 18:30:41","AP02SDTM":"2021-08-20 18:30:41","AP02EDTM":"2022-08-21 00:30:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-21","EOSDY":1096,"LSTALVDT":"2022-09-01","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2975,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.60343,"AVALU":"mg/L","BASE2":9.21107,"BASE":10.04382,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.39237,"PCHG2":15.11626,"CHG":0.55961,"PCHG":5.57169,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"1","BTOXGR":"1","ADTM":"2022-07-18 06:30:41","ADY":1062,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-54","SUBJID":"id-54","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.81516,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-17","TRTSDTM":"2019-08-21 06:30:41","TRTEDTM":"2022-08-21 00:30:41","TRT01SDTM":"2019-08-21 06:30:41","TRT01EDTM":"2021-08-20 18:30:41","TRT02SDTM":"2021-08-20 18:30:41","TRT02EDTM":"2022-08-21 00:30:41","AP01SDTM":"2019-08-21 06:30:41","AP01EDTM":"2021-08-20 18:30:41","AP02SDTM":"2021-08-20 18:30:41","AP02EDTM":"2022-08-21 00:30:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-21","EOSDY":1096,"LSTALVDT":"2022-09-01","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":819,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9511,"AVALU":"g/L","BASE2":2.9511,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-09 06:30:41","ADY":262,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-54","SUBJID":"id-54","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.81516,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-17","TRTSDTM":"2019-08-21 06:30:41","TRTEDTM":"2022-08-21 00:30:41","TRT01SDTM":"2019-08-21 06:30:41","TRT01EDTM":"2021-08-20 18:30:41","TRT02SDTM":"2021-08-20 18:30:41","TRT02EDTM":"2022-08-21 00:30:41","AP01SDTM":"2019-08-21 06:30:41","AP01EDTM":"2021-08-20 18:30:41","AP02SDTM":"2021-08-20 18:30:41","AP02EDTM":"2022-08-21 00:30:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-21","EOSDY":1096,"LSTALVDT":"2022-09-01","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3634,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74127,"AVALU":"g/L","BASE2":2.9511,"BASE":2.74127,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.20983,"PCHG2":-7.1103,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-12 06:30:41","ADY":265,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-54","SUBJID":"id-54","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.81516,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-17","TRTSDTM":"2019-08-21 06:30:41","TRTEDTM":"2022-08-21 00:30:41","TRT01SDTM":"2019-08-21 06:30:41","TRT01EDTM":"2021-08-20 18:30:41","TRT02SDTM":"2021-08-20 18:30:41","TRT02EDTM":"2022-08-21 00:30:41","AP01SDTM":"2019-08-21 06:30:41","AP01EDTM":"2021-08-20 18:30:41","AP02SDTM":"2021-08-20 18:30:41","AP02EDTM":"2022-08-21 00:30:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-21","EOSDY":1096,"LSTALVDT":"2022-09-01","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7069,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7546,"AVALU":"g/L","BASE2":2.9511,"BASE":2.74127,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19651,"PCHG2":-6.65879,"CHG":0.01332,"PCHG":0.48607,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-04 06:30:41","ADY":349,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-54","SUBJID":"id-54","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.81516,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-17","TRTSDTM":"2019-08-21 06:30:41","TRTEDTM":"2022-08-21 00:30:41","TRT01SDTM":"2019-08-21 06:30:41","TRT01EDTM":"2021-08-20 18:30:41","TRT02SDTM":"2021-08-20 18:30:41","TRT02EDTM":"2022-08-21 00:30:41","AP01SDTM":"2019-08-21 06:30:41","AP01EDTM":"2021-08-20 18:30:41","AP02SDTM":"2021-08-20 18:30:41","AP02EDTM":"2022-08-21 00:30:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-21","EOSDY":1096,"LSTALVDT":"2022-09-01","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4967,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79502,"AVALU":"g/L","BASE2":2.9511,"BASE":2.74127,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15609,"PCHG2":-5.28908,"CHG":0.05375,"PCHG":1.96063,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-19 06:30:41","ADY":364,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-54","SUBJID":"id-54","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.81516,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-17","TRTSDTM":"2019-08-21 06:30:41","TRTEDTM":"2022-08-21 00:30:41","TRT01SDTM":"2019-08-21 06:30:41","TRT01EDTM":"2021-08-20 18:30:41","TRT02SDTM":"2021-08-20 18:30:41","TRT02EDTM":"2022-08-21 00:30:41","AP01SDTM":"2019-08-21 06:30:41","AP01EDTM":"2021-08-20 18:30:41","AP02SDTM":"2021-08-20 18:30:41","AP02EDTM":"2022-08-21 00:30:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-21","EOSDY":1096,"LSTALVDT":"2022-09-01","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7651,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78529,"AVALU":"g/L","BASE2":2.9511,"BASE":2.74127,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16582,"PCHG2":-5.61884,"CHG":0.04401,"PCHG":1.60562,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-24 06:30:41","ADY":826,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-54","SUBJID":"id-54","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.81516,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-17","TRTSDTM":"2019-08-21 06:30:41","TRTEDTM":"2022-08-21 00:30:41","TRT01SDTM":"2019-08-21 06:30:41","TRT01EDTM":"2021-08-20 18:30:41","TRT02SDTM":"2021-08-20 18:30:41","TRT02EDTM":"2022-08-21 00:30:41","AP01SDTM":"2019-08-21 06:30:41","AP01EDTM":"2021-08-20 18:30:41","AP02SDTM":"2021-08-20 18:30:41","AP02EDTM":"2022-08-21 00:30:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-21","EOSDY":1096,"LSTALVDT":"2022-09-01","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2944,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98619,"AVALU":"g/L","BASE2":2.9511,"BASE":2.74127,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03509,"PCHG2":1.18891,"CHG":0.24492,"PCHG":8.93447,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-07 06:30:41","ADY":929,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-54","SUBJID":"id-54","SITEID":"CHN-11","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.81516,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-17","TRTSDTM":"2019-08-21 06:30:41","TRTEDTM":"2022-08-21 00:30:41","TRT01SDTM":"2019-08-21 06:30:41","TRT01EDTM":"2021-08-20 18:30:41","TRT02SDTM":"2021-08-20 18:30:41","TRT02EDTM":"2022-08-21 00:30:41","AP01SDTM":"2019-08-21 06:30:41","AP01EDTM":"2021-08-20 18:30:41","AP02SDTM":"2021-08-20 18:30:41","AP02EDTM":"2022-08-21 00:30:41","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-21","EOSDY":1096,"LSTALVDT":"2022-09-01","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7610,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75041,"AVALU":"g/L","BASE2":2.9511,"BASE":2.74127,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.2007,"PCHG2":-6.80079,"CHG":0.00913,"PCHG":0.3332,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-18 06:30:41","ADY":1062,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-55","SUBJID":"id-55","SITEID":"CHN-11","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.30181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-20","TRTSDTM":"2020-11-23 17:03:42","TRTEDTM":"2023-11-24 11:03:42","TRT01SDTM":"2020-11-23 17:03:42","TRT01EDTM":"2022-11-24 05:03:42","TRT02SDTM":"2022-11-24 05:03:42","TRT02EDTM":"2023-11-24 11:03:42","AP01SDTM":"2020-11-23 17:03:42","AP01EDTM":"2022-11-24 05:03:42","AP02SDTM":"2022-11-24 05:03:42","AP02EDTM":"2023-11-24 11:03:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-24","EOSDY":1096,"LSTALVDT":"2023-12-21","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8313,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.26423,"AVALU":"U/L","BASE2":6.26423,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-07-25 17:03:42","ADY":244,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-55","SUBJID":"id-55","SITEID":"CHN-11","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.30181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-20","TRTSDTM":"2020-11-23 17:03:42","TRTEDTM":"2023-11-24 11:03:42","TRT01SDTM":"2020-11-23 17:03:42","TRT01EDTM":"2022-11-24 05:03:42","TRT02SDTM":"2022-11-24 05:03:42","TRT02EDTM":"2023-11-24 11:03:42","AP01SDTM":"2020-11-23 17:03:42","AP01EDTM":"2022-11-24 05:03:42","AP02SDTM":"2022-11-24 05:03:42","AP02EDTM":"2023-11-24 11:03:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-24","EOSDY":1096,"LSTALVDT":"2023-12-21","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6424,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":35.25561,"AVALU":"U/L","BASE2":6.26423,"BASE":35.25561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":28.99138,"PCHG2":462.80831,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-09 17:03:42","ADY":532,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-55","SUBJID":"id-55","SITEID":"CHN-11","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.30181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-20","TRTSDTM":"2020-11-23 17:03:42","TRTEDTM":"2023-11-24 11:03:42","TRT01SDTM":"2020-11-23 17:03:42","TRT01EDTM":"2022-11-24 05:03:42","TRT02SDTM":"2022-11-24 05:03:42","TRT02EDTM":"2023-11-24 11:03:42","AP01SDTM":"2020-11-23 17:03:42","AP01EDTM":"2022-11-24 05:03:42","AP02SDTM":"2022-11-24 05:03:42","AP02EDTM":"2023-11-24 11:03:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-24","EOSDY":1096,"LSTALVDT":"2023-12-21","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5488,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.10596,"AVALU":"U/L","BASE2":6.26423,"BASE":35.25561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":17.84173,"PCHG2":284.81924,"CHG":-11.14965,"PCHG":-31.62517,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-31 17:03:42","ADY":554,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-55","SUBJID":"id-55","SITEID":"CHN-11","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.30181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-20","TRTSDTM":"2020-11-23 17:03:42","TRTEDTM":"2023-11-24 11:03:42","TRT01SDTM":"2020-11-23 17:03:42","TRT01EDTM":"2022-11-24 05:03:42","TRT02SDTM":"2022-11-24 05:03:42","TRT02EDTM":"2023-11-24 11:03:42","AP01SDTM":"2020-11-23 17:03:42","AP01EDTM":"2022-11-24 05:03:42","AP02SDTM":"2022-11-24 05:03:42","AP02EDTM":"2023-11-24 11:03:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-24","EOSDY":1096,"LSTALVDT":"2023-12-21","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":541,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.81363,"AVALU":"U/L","BASE2":6.26423,"BASE":35.25561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.5494,"PCHG2":216.29785,"CHG":-15.44198,"PCHG":-43.80007,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-21 17:03:42","ADY":575,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-55","SUBJID":"id-55","SITEID":"CHN-11","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.30181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-20","TRTSDTM":"2020-11-23 17:03:42","TRTEDTM":"2023-11-24 11:03:42","TRT01SDTM":"2020-11-23 17:03:42","TRT01EDTM":"2022-11-24 05:03:42","TRT02SDTM":"2022-11-24 05:03:42","TRT02EDTM":"2023-11-24 11:03:42","AP01SDTM":"2020-11-23 17:03:42","AP01EDTM":"2022-11-24 05:03:42","AP02SDTM":"2022-11-24 05:03:42","AP02EDTM":"2023-11-24 11:03:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-24","EOSDY":1096,"LSTALVDT":"2023-12-21","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5006,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.7229,"AVALU":"U/L","BASE2":6.26423,"BASE":35.25561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.45867,"PCHG2":182.92217,"CHG":-17.53271,"PCHG":-49.73028,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-01 17:03:42","ADY":616,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-55","SUBJID":"id-55","SITEID":"CHN-11","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.30181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-20","TRTSDTM":"2020-11-23 17:03:42","TRTEDTM":"2023-11-24 11:03:42","TRT01SDTM":"2020-11-23 17:03:42","TRT01EDTM":"2022-11-24 05:03:42","TRT02SDTM":"2022-11-24 05:03:42","TRT02EDTM":"2023-11-24 11:03:42","AP01SDTM":"2020-11-23 17:03:42","AP01EDTM":"2022-11-24 05:03:42","AP02SDTM":"2022-11-24 05:03:42","AP02EDTM":"2023-11-24 11:03:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-24","EOSDY":1096,"LSTALVDT":"2023-12-21","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1663,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.00812,"AVALU":"U/L","BASE2":6.26423,"BASE":35.25561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.74389,"PCHG2":171.51177,"CHG":-18.24749,"PCHG":-51.75768,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-28 17:03:42","ADY":674,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-55","SUBJID":"id-55","SITEID":"CHN-11","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.30181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-20","TRTSDTM":"2020-11-23 17:03:42","TRTEDTM":"2023-11-24 11:03:42","TRT01SDTM":"2020-11-23 17:03:42","TRT01EDTM":"2022-11-24 05:03:42","TRT02SDTM":"2022-11-24 05:03:42","TRT02EDTM":"2023-11-24 11:03:42","AP01SDTM":"2020-11-23 17:03:42","AP01EDTM":"2022-11-24 05:03:42","AP02SDTM":"2022-11-24 05:03:42","AP02EDTM":"2023-11-24 11:03:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-24","EOSDY":1096,"LSTALVDT":"2023-12-21","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5576,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.93254,"AVALU":"U/L","BASE2":6.26423,"BASE":35.25561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.66831,"PCHG2":26.63233,"CHG":-27.32307,"PCHG":-77.49992,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-14 17:03:42","ADY":813,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-55","SUBJID":"id-55","SITEID":"CHN-11","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.30181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-20","TRTSDTM":"2020-11-23 17:03:42","TRTEDTM":"2023-11-24 11:03:42","TRT01SDTM":"2020-11-23 17:03:42","TRT01EDTM":"2022-11-24 05:03:42","TRT02SDTM":"2022-11-24 05:03:42","TRT02EDTM":"2023-11-24 11:03:42","AP01SDTM":"2020-11-23 17:03:42","AP01EDTM":"2022-11-24 05:03:42","AP02SDTM":"2022-11-24 05:03:42","AP02EDTM":"2023-11-24 11:03:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-24","EOSDY":1096,"LSTALVDT":"2023-12-21","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2463,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.03959,"AVALU":"mg/L","BASE2":11.03959,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-07-25 17:03:42","ADY":244,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-55","SUBJID":"id-55","SITEID":"CHN-11","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.30181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-20","TRTSDTM":"2020-11-23 17:03:42","TRTEDTM":"2023-11-24 11:03:42","TRT01SDTM":"2020-11-23 17:03:42","TRT01EDTM":"2022-11-24 05:03:42","TRT02SDTM":"2022-11-24 05:03:42","TRT02EDTM":"2023-11-24 11:03:42","AP01SDTM":"2020-11-23 17:03:42","AP01EDTM":"2022-11-24 05:03:42","AP02SDTM":"2022-11-24 05:03:42","AP02EDTM":"2023-11-24 11:03:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-24","EOSDY":1096,"LSTALVDT":"2023-12-21","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4468,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.12708,"AVALU":"mg/L","BASE2":11.03959,"BASE":9.12708,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.91251,"PCHG2":-17.32411,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-09 17:03:42","ADY":532,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-55","SUBJID":"id-55","SITEID":"CHN-11","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.30181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-20","TRTSDTM":"2020-11-23 17:03:42","TRTEDTM":"2023-11-24 11:03:42","TRT01SDTM":"2020-11-23 17:03:42","TRT01EDTM":"2022-11-24 05:03:42","TRT02SDTM":"2022-11-24 05:03:42","TRT02EDTM":"2023-11-24 11:03:42","AP01SDTM":"2020-11-23 17:03:42","AP01EDTM":"2022-11-24 05:03:42","AP02SDTM":"2022-11-24 05:03:42","AP02EDTM":"2023-11-24 11:03:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-24","EOSDY":1096,"LSTALVDT":"2023-12-21","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3478,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.96131,"AVALU":"mg/L","BASE2":11.03959,"BASE":9.12708,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.07828,"PCHG2":-9.7674,"CHG":0.83423,"PCHG":9.14016,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-31 17:03:42","ADY":554,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-55","SUBJID":"id-55","SITEID":"CHN-11","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.30181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-20","TRTSDTM":"2020-11-23 17:03:42","TRTEDTM":"2023-11-24 11:03:42","TRT01SDTM":"2020-11-23 17:03:42","TRT01EDTM":"2022-11-24 05:03:42","TRT02SDTM":"2022-11-24 05:03:42","TRT02EDTM":"2023-11-24 11:03:42","AP01SDTM":"2020-11-23 17:03:42","AP01EDTM":"2022-11-24 05:03:42","AP02SDTM":"2022-11-24 05:03:42","AP02EDTM":"2023-11-24 11:03:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-24","EOSDY":1096,"LSTALVDT":"2023-12-21","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3251,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.36981,"AVALU":"mg/L","BASE2":11.03959,"BASE":9.12708,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.66978,"PCHG2":-24.18368,"CHG":-0.75727,"PCHG":-8.29694,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-21 17:03:42","ADY":575,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-55","SUBJID":"id-55","SITEID":"CHN-11","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.30181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-20","TRTSDTM":"2020-11-23 17:03:42","TRTEDTM":"2023-11-24 11:03:42","TRT01SDTM":"2020-11-23 17:03:42","TRT01EDTM":"2022-11-24 05:03:42","TRT02SDTM":"2022-11-24 05:03:42","TRT02EDTM":"2023-11-24 11:03:42","AP01SDTM":"2020-11-23 17:03:42","AP01EDTM":"2022-11-24 05:03:42","AP02SDTM":"2022-11-24 05:03:42","AP02EDTM":"2023-11-24 11:03:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-24","EOSDY":1096,"LSTALVDT":"2023-12-21","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2703,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.41199,"AVALU":"mg/L","BASE2":11.03959,"BASE":9.12708,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.6276,"PCHG2":-14.74328,"CHG":0.28491,"PCHG":3.12162,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-01 17:03:42","ADY":616,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-55","SUBJID":"id-55","SITEID":"CHN-11","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.30181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-20","TRTSDTM":"2020-11-23 17:03:42","TRTEDTM":"2023-11-24 11:03:42","TRT01SDTM":"2020-11-23 17:03:42","TRT01EDTM":"2022-11-24 05:03:42","TRT02SDTM":"2022-11-24 05:03:42","TRT02EDTM":"2023-11-24 11:03:42","AP01SDTM":"2020-11-23 17:03:42","AP01EDTM":"2022-11-24 05:03:42","AP02SDTM":"2022-11-24 05:03:42","AP02EDTM":"2023-11-24 11:03:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-24","EOSDY":1096,"LSTALVDT":"2023-12-21","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6411,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.66309,"AVALU":"mg/L","BASE2":11.03959,"BASE":9.12708,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.3765,"PCHG2":-21.52707,"CHG":-0.46399,"PCHG":-5.08366,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-28 17:03:42","ADY":674,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-55","SUBJID":"id-55","SITEID":"CHN-11","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.30181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-20","TRTSDTM":"2020-11-23 17:03:42","TRTEDTM":"2023-11-24 11:03:42","TRT01SDTM":"2020-11-23 17:03:42","TRT01EDTM":"2022-11-24 05:03:42","TRT02SDTM":"2022-11-24 05:03:42","TRT02EDTM":"2023-11-24 11:03:42","AP01SDTM":"2020-11-23 17:03:42","AP01EDTM":"2022-11-24 05:03:42","AP02SDTM":"2022-11-24 05:03:42","AP02EDTM":"2023-11-24 11:03:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-24","EOSDY":1096,"LSTALVDT":"2023-12-21","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6266,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.75448,"AVALU":"mg/L","BASE2":11.03959,"BASE":9.12708,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.28511,"PCHG2":-11.64091,"CHG":0.6274,"PCHG":6.87407,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-14 17:03:42","ADY":813,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-55","SUBJID":"id-55","SITEID":"CHN-11","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.30181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-20","TRTSDTM":"2020-11-23 17:03:42","TRTEDTM":"2023-11-24 11:03:42","TRT01SDTM":"2020-11-23 17:03:42","TRT01EDTM":"2022-11-24 05:03:42","TRT02SDTM":"2022-11-24 05:03:42","TRT02EDTM":"2023-11-24 11:03:42","AP01SDTM":"2020-11-23 17:03:42","AP01EDTM":"2022-11-24 05:03:42","AP02SDTM":"2022-11-24 05:03:42","AP02EDTM":"2023-11-24 11:03:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-24","EOSDY":1096,"LSTALVDT":"2023-12-21","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":523,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88239,"AVALU":"g/L","BASE2":2.88239,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-25 17:03:42","ADY":244,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-55","SUBJID":"id-55","SITEID":"CHN-11","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.30181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-20","TRTSDTM":"2020-11-23 17:03:42","TRTEDTM":"2023-11-24 11:03:42","TRT01SDTM":"2020-11-23 17:03:42","TRT01EDTM":"2022-11-24 05:03:42","TRT02SDTM":"2022-11-24 05:03:42","TRT02EDTM":"2023-11-24 11:03:42","AP01SDTM":"2020-11-23 17:03:42","AP01EDTM":"2022-11-24 05:03:42","AP02SDTM":"2022-11-24 05:03:42","AP02EDTM":"2023-11-24 11:03:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-24","EOSDY":1096,"LSTALVDT":"2023-12-21","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4640,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75276,"AVALU":"g/L","BASE2":2.88239,"BASE":2.75276,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.12963,"PCHG2":-4.49741,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-09 17:03:42","ADY":532,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-55","SUBJID":"id-55","SITEID":"CHN-11","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.30181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-20","TRTSDTM":"2020-11-23 17:03:42","TRTEDTM":"2023-11-24 11:03:42","TRT01SDTM":"2020-11-23 17:03:42","TRT01EDTM":"2022-11-24 05:03:42","TRT02SDTM":"2022-11-24 05:03:42","TRT02EDTM":"2023-11-24 11:03:42","AP01SDTM":"2020-11-23 17:03:42","AP01EDTM":"2022-11-24 05:03:42","AP02SDTM":"2022-11-24 05:03:42","AP02EDTM":"2023-11-24 11:03:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-24","EOSDY":1096,"LSTALVDT":"2023-12-21","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4542,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0747,"AVALU":"g/L","BASE2":2.88239,"BASE":2.75276,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.19231,"PCHG2":6.67181,"CHG":0.32194,"PCHG":11.6952,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-05-31 17:03:42","ADY":554,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-55","SUBJID":"id-55","SITEID":"CHN-11","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.30181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-20","TRTSDTM":"2020-11-23 17:03:42","TRTEDTM":"2023-11-24 11:03:42","TRT01SDTM":"2020-11-23 17:03:42","TRT01EDTM":"2022-11-24 05:03:42","TRT02SDTM":"2022-11-24 05:03:42","TRT02EDTM":"2023-11-24 11:03:42","AP01SDTM":"2020-11-23 17:03:42","AP01EDTM":"2022-11-24 05:03:42","AP02SDTM":"2022-11-24 05:03:42","AP02EDTM":"2023-11-24 11:03:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-24","EOSDY":1096,"LSTALVDT":"2023-12-21","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":556,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87153,"AVALU":"g/L","BASE2":2.88239,"BASE":2.75276,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01086,"PCHG2":-0.37661,"CHG":0.11878,"PCHG":4.31486,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-21 17:03:42","ADY":575,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-55","SUBJID":"id-55","SITEID":"CHN-11","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.30181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-20","TRTSDTM":"2020-11-23 17:03:42","TRTEDTM":"2023-11-24 11:03:42","TRT01SDTM":"2020-11-23 17:03:42","TRT01EDTM":"2022-11-24 05:03:42","TRT02SDTM":"2022-11-24 05:03:42","TRT02EDTM":"2023-11-24 11:03:42","AP01SDTM":"2020-11-23 17:03:42","AP01EDTM":"2022-11-24 05:03:42","AP02SDTM":"2022-11-24 05:03:42","AP02EDTM":"2023-11-24 11:03:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-24","EOSDY":1096,"LSTALVDT":"2023-12-21","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4880,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.25601,"AVALU":"g/L","BASE2":2.88239,"BASE":2.75276,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.37362,"PCHG2":12.96213,"CHG":0.50325,"PCHG":18.28174,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-08-01 17:03:42","ADY":616,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-55","SUBJID":"id-55","SITEID":"CHN-11","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.30181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-20","TRTSDTM":"2020-11-23 17:03:42","TRTEDTM":"2023-11-24 11:03:42","TRT01SDTM":"2020-11-23 17:03:42","TRT01EDTM":"2022-11-24 05:03:42","TRT02SDTM":"2022-11-24 05:03:42","TRT02EDTM":"2023-11-24 11:03:42","AP01SDTM":"2020-11-23 17:03:42","AP01EDTM":"2022-11-24 05:03:42","AP02SDTM":"2022-11-24 05:03:42","AP02EDTM":"2023-11-24 11:03:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-24","EOSDY":1096,"LSTALVDT":"2023-12-21","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6292,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.72875,"AVALU":"g/L","BASE2":2.88239,"BASE":2.75276,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15363,"PCHG2":-5.33009,"CHG":-0.024,"PCHG":-0.8719,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-28 17:03:42","ADY":674,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-55","SUBJID":"id-55","SITEID":"CHN-11","AGE":43,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.30181,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-20","TRTSDTM":"2020-11-23 17:03:42","TRTEDTM":"2023-11-24 11:03:42","TRT01SDTM":"2020-11-23 17:03:42","TRT01EDTM":"2022-11-24 05:03:42","TRT02SDTM":"2022-11-24 05:03:42","TRT02EDTM":"2023-11-24 11:03:42","AP01SDTM":"2020-11-23 17:03:42","AP01EDTM":"2022-11-24 05:03:42","AP02SDTM":"2022-11-24 05:03:42","AP02EDTM":"2023-11-24 11:03:42","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-24","EOSDY":1096,"LSTALVDT":"2023-12-21","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3574,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97407,"AVALU":"g/L","BASE2":2.88239,"BASE":2.75276,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09168,"PCHG2":3.18058,"CHG":0.22131,"PCHG":8.03956,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-14 17:03:42","ADY":813,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-60","SUBJID":"id-60","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.21027,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-09 10:45:02","TRTEDTM":"2022-09-09 04:45:02","TRT01SDTM":"2019-09-09 10:45:02","TRT01EDTM":"2021-09-08 22:45:02","TRT02SDTM":"2021-09-08 22:45:02","TRT02EDTM":"2022-09-09 04:45:02","AP01SDTM":"2019-09-09 10:45:02","AP01EDTM":"2021-09-08 22:45:02","AP02SDTM":"2021-09-08 22:45:02","AP02EDTM":"2022-09-09 04:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-09","EOSDY":1096,"LSTALVDT":"2022-09-22","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8058,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.86833,"AVALU":"U/L","BASE2":33.86833,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-17 10:45:02","ADY":161,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-60","SUBJID":"id-60","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.21027,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-09 10:45:02","TRTEDTM":"2022-09-09 04:45:02","TRT01SDTM":"2019-09-09 10:45:02","TRT01EDTM":"2021-09-08 22:45:02","TRT02SDTM":"2021-09-08 22:45:02","TRT02EDTM":"2022-09-09 04:45:02","AP01SDTM":"2019-09-09 10:45:02","AP01EDTM":"2021-09-08 22:45:02","AP02SDTM":"2021-09-08 22:45:02","AP02EDTM":"2022-09-09 04:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-09","EOSDY":1096,"LSTALVDT":"2022-09-22","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7449,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":54.39574,"AVALU":"U/L","BASE2":33.86833,"BASE":54.39574,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":20.5274,"PCHG2":60.60942,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-03 10:45:02","ADY":176,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-60","SUBJID":"id-60","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.21027,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-09 10:45:02","TRTEDTM":"2022-09-09 04:45:02","TRT01SDTM":"2019-09-09 10:45:02","TRT01EDTM":"2021-09-08 22:45:02","TRT02SDTM":"2021-09-08 22:45:02","TRT02EDTM":"2022-09-09 04:45:02","AP01SDTM":"2019-09-09 10:45:02","AP01EDTM":"2021-09-08 22:45:02","AP02SDTM":"2021-09-08 22:45:02","AP02EDTM":"2022-09-09 04:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-09","EOSDY":1096,"LSTALVDT":"2022-09-22","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1347,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.166,"AVALU":"U/L","BASE2":33.86833,"BASE":54.39574,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.70233,"PCHG2":-10.93155,"CHG":-24.22973,"PCHG":-44.54345,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-01 10:45:02","ADY":419,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-60","SUBJID":"id-60","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.21027,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-09 10:45:02","TRTEDTM":"2022-09-09 04:45:02","TRT01SDTM":"2019-09-09 10:45:02","TRT01EDTM":"2021-09-08 22:45:02","TRT02SDTM":"2021-09-08 22:45:02","TRT02EDTM":"2022-09-09 04:45:02","AP01SDTM":"2019-09-09 10:45:02","AP01EDTM":"2021-09-08 22:45:02","AP02SDTM":"2021-09-08 22:45:02","AP02EDTM":"2022-09-09 04:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-09","EOSDY":1096,"LSTALVDT":"2022-09-22","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3792,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.46096,"AVALU":"U/L","BASE2":33.86833,"BASE":54.39574,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-25.40738,"PCHG2":-75.01809,"CHG":-45.93478,"PCHG":-84.44555,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-04 10:45:02","ADY":573,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-60","SUBJID":"id-60","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.21027,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-09 10:45:02","TRTEDTM":"2022-09-09 04:45:02","TRT01SDTM":"2019-09-09 10:45:02","TRT01EDTM":"2021-09-08 22:45:02","TRT02SDTM":"2021-09-08 22:45:02","TRT02EDTM":"2022-09-09 04:45:02","AP01SDTM":"2019-09-09 10:45:02","AP01EDTM":"2021-09-08 22:45:02","AP02SDTM":"2021-09-08 22:45:02","AP02EDTM":"2022-09-09 04:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-09","EOSDY":1096,"LSTALVDT":"2022-09-22","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6655,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.09103,"AVALU":"U/L","BASE2":33.86833,"BASE":54.39574,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-25.7773,"PCHG2":-76.11034,"CHG":-46.30471,"PCHG":-85.12562,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-20 10:45:02","ADY":589,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-60","SUBJID":"id-60","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.21027,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-09 10:45:02","TRTEDTM":"2022-09-09 04:45:02","TRT01SDTM":"2019-09-09 10:45:02","TRT01EDTM":"2021-09-08 22:45:02","TRT02SDTM":"2021-09-08 22:45:02","TRT02EDTM":"2022-09-09 04:45:02","AP01SDTM":"2019-09-09 10:45:02","AP01EDTM":"2021-09-08 22:45:02","AP02SDTM":"2021-09-08 22:45:02","AP02EDTM":"2022-09-09 04:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-09","EOSDY":1096,"LSTALVDT":"2022-09-22","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5845,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.94917,"AVALU":"U/L","BASE2":33.86833,"BASE":54.39574,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-20.91916,"PCHG2":-61.76614,"CHG":-41.44656,"PCHG":-76.19451,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-02 10:45:02","ADY":877,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-60","SUBJID":"id-60","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.21027,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-09 10:45:02","TRTEDTM":"2022-09-09 04:45:02","TRT01SDTM":"2019-09-09 10:45:02","TRT01EDTM":"2021-09-08 22:45:02","TRT02SDTM":"2021-09-08 22:45:02","TRT02EDTM":"2022-09-09 04:45:02","AP01SDTM":"2019-09-09 10:45:02","AP01EDTM":"2021-09-08 22:45:02","AP02SDTM":"2021-09-08 22:45:02","AP02EDTM":"2022-09-09 04:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-09","EOSDY":1096,"LSTALVDT":"2022-09-22","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7137,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.79813,"AVALU":"U/L","BASE2":33.86833,"BASE":54.39574,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-27.07021,"PCHG2":-79.92777,"CHG":-47.59761,"PCHG":-87.50246,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-07-09 10:45:02","ADY":1034,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-60","SUBJID":"id-60","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.21027,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-09 10:45:02","TRTEDTM":"2022-09-09 04:45:02","TRT01SDTM":"2019-09-09 10:45:02","TRT01EDTM":"2021-09-08 22:45:02","TRT02SDTM":"2021-09-08 22:45:02","TRT02EDTM":"2022-09-09 04:45:02","AP01SDTM":"2019-09-09 10:45:02","AP01EDTM":"2021-09-08 22:45:02","AP02SDTM":"2021-09-08 22:45:02","AP02EDTM":"2022-09-09 04:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-09","EOSDY":1096,"LSTALVDT":"2022-09-22","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4905,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.80742,"AVALU":"mg/L","BASE2":8.80742,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-02-17 10:45:02","ADY":161,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-60","SUBJID":"id-60","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.21027,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-09 10:45:02","TRTEDTM":"2022-09-09 04:45:02","TRT01SDTM":"2019-09-09 10:45:02","TRT01EDTM":"2021-09-08 22:45:02","TRT02SDTM":"2021-09-08 22:45:02","TRT02EDTM":"2022-09-09 04:45:02","AP01SDTM":"2019-09-09 10:45:02","AP01EDTM":"2021-09-08 22:45:02","AP02SDTM":"2021-09-08 22:45:02","AP02EDTM":"2022-09-09 04:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-09","EOSDY":1096,"LSTALVDT":"2022-09-22","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2854,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.21832,"AVALU":"mg/L","BASE2":8.80742,"BASE":10.21832,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.4109,"PCHG2":16.01942,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2020-03-03 10:45:02","ADY":176,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-60","SUBJID":"id-60","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.21027,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-09 10:45:02","TRTEDTM":"2022-09-09 04:45:02","TRT01SDTM":"2019-09-09 10:45:02","TRT01EDTM":"2021-09-08 22:45:02","TRT02SDTM":"2021-09-08 22:45:02","TRT02EDTM":"2022-09-09 04:45:02","AP01SDTM":"2019-09-09 10:45:02","AP01EDTM":"2021-09-08 22:45:02","AP02SDTM":"2021-09-08 22:45:02","AP02EDTM":"2022-09-09 04:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-09","EOSDY":1096,"LSTALVDT":"2022-09-22","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7578,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.73815,"AVALU":"mg/L","BASE2":8.80742,"BASE":10.21832,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.06927,"PCHG2":-12.14056,"CHG":-2.48017,"PCHG":-24.27178,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-3","BTOXGR":"3","ADTM":"2020-11-01 10:45:02","ADY":419,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-60","SUBJID":"id-60","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.21027,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-09 10:45:02","TRTEDTM":"2022-09-09 04:45:02","TRT01SDTM":"2019-09-09 10:45:02","TRT01EDTM":"2021-09-08 22:45:02","TRT02SDTM":"2021-09-08 22:45:02","TRT02EDTM":"2022-09-09 04:45:02","AP01SDTM":"2019-09-09 10:45:02","AP01EDTM":"2021-09-08 22:45:02","AP02SDTM":"2021-09-08 22:45:02","AP02EDTM":"2022-09-09 04:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-09","EOSDY":1096,"LSTALVDT":"2022-09-22","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1879,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.27283,"AVALU":"mg/L","BASE2":8.80742,"BASE":10.21832,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.53459,"PCHG2":-6.06976,"CHG":-1.94549,"PCHG":-19.03921,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-04-04 10:45:02","ADY":573,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-60","SUBJID":"id-60","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.21027,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-09 10:45:02","TRTEDTM":"2022-09-09 04:45:02","TRT01SDTM":"2019-09-09 10:45:02","TRT01EDTM":"2021-09-08 22:45:02","TRT02SDTM":"2021-09-08 22:45:02","TRT02EDTM":"2022-09-09 04:45:02","AP01SDTM":"2019-09-09 10:45:02","AP01EDTM":"2021-09-08 22:45:02","AP02SDTM":"2021-09-08 22:45:02","AP02EDTM":"2022-09-09 04:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-09","EOSDY":1096,"LSTALVDT":"2022-09-22","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3725,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.30544,"AVALU":"mg/L","BASE2":8.80742,"BASE":10.21832,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.50198,"PCHG2":-5.69951,"CHG":-1.91288,"PCHG":-18.72009,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-04-20 10:45:02","ADY":589,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-60","SUBJID":"id-60","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.21027,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-09 10:45:02","TRTEDTM":"2022-09-09 04:45:02","TRT01SDTM":"2019-09-09 10:45:02","TRT01EDTM":"2021-09-08 22:45:02","TRT02SDTM":"2021-09-08 22:45:02","TRT02EDTM":"2022-09-09 04:45:02","AP01SDTM":"2019-09-09 10:45:02","AP01EDTM":"2021-09-08 22:45:02","AP02SDTM":"2021-09-08 22:45:02","AP02EDTM":"2022-09-09 04:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-09","EOSDY":1096,"LSTALVDT":"2022-09-22","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2334,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.66937,"AVALU":"mg/L","BASE2":8.80742,"BASE":10.21832,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.86195,"PCHG2":21.14067,"CHG":0.45105,"PCHG":4.41413,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"3","BTOXGR":"3","ADTM":"2022-02-02 10:45:02","ADY":877,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-60","SUBJID":"id-60","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.21027,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-09 10:45:02","TRTEDTM":"2022-09-09 04:45:02","TRT01SDTM":"2019-09-09 10:45:02","TRT01EDTM":"2021-09-08 22:45:02","TRT02SDTM":"2021-09-08 22:45:02","TRT02EDTM":"2022-09-09 04:45:02","AP01SDTM":"2019-09-09 10:45:02","AP01EDTM":"2021-09-08 22:45:02","AP02SDTM":"2021-09-08 22:45:02","AP02EDTM":"2022-09-09 04:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-09","EOSDY":1096,"LSTALVDT":"2022-09-22","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2274,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.44866,"AVALU":"mg/L","BASE2":8.80742,"BASE":10.21832,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.35875,"PCHG2":-15.42739,"CHG":-2.76965,"PCHG":-27.10478,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-2","BTOXGR":"3","ADTM":"2022-07-09 10:45:02","ADY":1034,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-60","SUBJID":"id-60","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.21027,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-09 10:45:02","TRTEDTM":"2022-09-09 04:45:02","TRT01SDTM":"2019-09-09 10:45:02","TRT01EDTM":"2021-09-08 22:45:02","TRT02SDTM":"2021-09-08 22:45:02","TRT02EDTM":"2022-09-09 04:45:02","AP01SDTM":"2019-09-09 10:45:02","AP01EDTM":"2021-09-08 22:45:02","AP02SDTM":"2021-09-08 22:45:02","AP02EDTM":"2022-09-09 04:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-09","EOSDY":1096,"LSTALVDT":"2022-09-22","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":531,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.66257,"AVALU":"g/L","BASE2":2.66257,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-17 10:45:02","ADY":161,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-60","SUBJID":"id-60","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.21027,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-09 10:45:02","TRTEDTM":"2022-09-09 04:45:02","TRT01SDTM":"2019-09-09 10:45:02","TRT01EDTM":"2021-09-08 22:45:02","TRT02SDTM":"2021-09-08 22:45:02","TRT02EDTM":"2022-09-09 04:45:02","AP01SDTM":"2019-09-09 10:45:02","AP01EDTM":"2021-09-08 22:45:02","AP02SDTM":"2021-09-08 22:45:02","AP02EDTM":"2022-09-09 04:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-09","EOSDY":1096,"LSTALVDT":"2022-09-22","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6183,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92973,"AVALU":"g/L","BASE2":2.66257,"BASE":2.92973,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.26716,"PCHG2":10.03378,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-03 10:45:02","ADY":176,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-60","SUBJID":"id-60","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.21027,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-09 10:45:02","TRTEDTM":"2022-09-09 04:45:02","TRT01SDTM":"2019-09-09 10:45:02","TRT01EDTM":"2021-09-08 22:45:02","TRT02SDTM":"2021-09-08 22:45:02","TRT02EDTM":"2022-09-09 04:45:02","AP01SDTM":"2019-09-09 10:45:02","AP01EDTM":"2021-09-08 22:45:02","AP02SDTM":"2021-09-08 22:45:02","AP02EDTM":"2022-09-09 04:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-09","EOSDY":1096,"LSTALVDT":"2022-09-22","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6036,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93699,"AVALU":"g/L","BASE2":2.66257,"BASE":2.92973,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.27442,"PCHG2":10.30663,"CHG":0.00726,"PCHG":0.24797,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-01 10:45:02","ADY":419,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-60","SUBJID":"id-60","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.21027,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-09 10:45:02","TRTEDTM":"2022-09-09 04:45:02","TRT01SDTM":"2019-09-09 10:45:02","TRT01EDTM":"2021-09-08 22:45:02","TRT02SDTM":"2021-09-08 22:45:02","TRT02EDTM":"2022-09-09 04:45:02","AP01SDTM":"2019-09-09 10:45:02","AP01EDTM":"2021-09-08 22:45:02","AP02SDTM":"2021-09-08 22:45:02","AP02EDTM":"2022-09-09 04:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-09","EOSDY":1096,"LSTALVDT":"2022-09-22","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2840,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98887,"AVALU":"g/L","BASE2":2.66257,"BASE":2.92973,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.3263,"PCHG2":12.255,"CHG":0.05914,"PCHG":2.01867,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-04 10:45:02","ADY":573,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-60","SUBJID":"id-60","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.21027,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-09 10:45:02","TRTEDTM":"2022-09-09 04:45:02","TRT01SDTM":"2019-09-09 10:45:02","TRT01EDTM":"2021-09-08 22:45:02","TRT02SDTM":"2021-09-08 22:45:02","TRT02EDTM":"2022-09-09 04:45:02","AP01SDTM":"2019-09-09 10:45:02","AP01EDTM":"2021-09-08 22:45:02","AP02SDTM":"2021-09-08 22:45:02","AP02EDTM":"2022-09-09 04:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-09","EOSDY":1096,"LSTALVDT":"2022-09-22","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3750,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86738,"AVALU":"g/L","BASE2":2.66257,"BASE":2.92973,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.20481,"PCHG2":7.69208,"CHG":-0.06235,"PCHG":-2.12817,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-20 10:45:02","ADY":589,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-60","SUBJID":"id-60","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.21027,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-09 10:45:02","TRTEDTM":"2022-09-09 04:45:02","TRT01SDTM":"2019-09-09 10:45:02","TRT01EDTM":"2021-09-08 22:45:02","TRT02SDTM":"2021-09-08 22:45:02","TRT02EDTM":"2022-09-09 04:45:02","AP01SDTM":"2019-09-09 10:45:02","AP01EDTM":"2021-09-08 22:45:02","AP02SDTM":"2021-09-08 22:45:02","AP02EDTM":"2022-09-09 04:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-09","EOSDY":1096,"LSTALVDT":"2022-09-22","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2872,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8524,"AVALU":"g/L","BASE2":2.66257,"BASE":2.92973,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18983,"PCHG2":7.12948,"CHG":-0.07733,"PCHG":-2.63946,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-02 10:45:02","ADY":877,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-60","SUBJID":"id-60","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.21027,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-09 10:45:02","TRTEDTM":"2022-09-09 04:45:02","TRT01SDTM":"2019-09-09 10:45:02","TRT01EDTM":"2021-09-08 22:45:02","TRT02SDTM":"2021-09-08 22:45:02","TRT02EDTM":"2022-09-09 04:45:02","AP01SDTM":"2019-09-09 10:45:02","AP01EDTM":"2021-09-08 22:45:02","AP02SDTM":"2021-09-08 22:45:02","AP02EDTM":"2022-09-09 04:45:02","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-09","EOSDY":1096,"LSTALVDT":"2022-09-22","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4304,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.11117,"AVALU":"g/L","BASE2":2.66257,"BASE":2.92973,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.4486,"PCHG2":16.84826,"CHG":0.18144,"PCHG":6.19308,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2022-07-09 10:45:02","ADY":1034,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-63","SUBJID":"id-63","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.80483,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-16 23:12:09","TRT01SDTM":"2019-10-16 23:12:09","AP01SDTM":"2019-10-16 23:12:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":508,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.99809,"AVALU":"U/L","BASE2":16.99809,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-07 23:12:09","ADY":22,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-63","SUBJID":"id-63","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.80483,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-16 23:12:09","TRT01SDTM":"2019-10-16 23:12:09","AP01SDTM":"2019-10-16 23:12:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8305,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.46905,"AVALU":"U/L","BASE2":16.99809,"BASE":21.46905,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":4.47096,"PCHG2":26.30272,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-06 23:12:09","ADY":51,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-63","SUBJID":"id-63","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.80483,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-16 23:12:09","TRT01SDTM":"2019-10-16 23:12:09","AP01SDTM":"2019-10-16 23:12:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6987,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.65354,"AVALU":"U/L","BASE2":16.99809,"BASE":21.46905,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.65545,"PCHG2":9.73902,"CHG":-2.81551,"PCHG":-13.11428,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-03 23:12:09","ADY":79,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-63","SUBJID":"id-63","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.80483,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-16 23:12:09","TRT01SDTM":"2019-10-16 23:12:09","AP01SDTM":"2019-10-16 23:12:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":124,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.59415,"AVALU":"U/L","BASE2":16.99809,"BASE":21.46905,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.59606,"PCHG2":68.21978,"CHG":7.1251,"PCHG":33.18778,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-14 23:12:09","ADY":90,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-63","SUBJID":"id-63","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.80483,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-16 23:12:09","TRT01SDTM":"2019-10-16 23:12:09","AP01SDTM":"2019-10-16 23:12:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6776,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.38299,"AVALU":"U/L","BASE2":16.99809,"BASE":21.46905,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.6151,"PCHG2":-21.2677,"CHG":-8.08606,"PCHG":-37.66381,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-31 23:12:09","ADY":107,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-63","SUBJID":"id-63","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.80483,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-16 23:12:09","TRT01SDTM":"2019-10-16 23:12:09","AP01SDTM":"2019-10-16 23:12:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5091,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.90878,"AVALU":"U/L","BASE2":16.99809,"BASE":21.46905,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.08931,"PCHG2":-41.70652,"CHG":-11.56027,"PCHG":-53.84622,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-10 23:12:09","ADY":330,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-63","SUBJID":"id-63","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.80483,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-16 23:12:09","TRT01SDTM":"2019-10-16 23:12:09","AP01SDTM":"2019-10-16 23:12:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8231,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.37782,"AVALU":"U/L","BASE2":16.99809,"BASE":21.46905,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.62027,"PCHG2":-86.01124,"CHG":-19.09123,"PCHG":-88.92442,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-09-04 23:12:09","ADY":689,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-63","SUBJID":"id-63","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.80483,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-16 23:12:09","TRT01SDTM":"2019-10-16 23:12:09","AP01SDTM":"2019-10-16 23:12:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4572,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.49253,"AVALU":"mg/L","BASE2":11.49253,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"3","BTOXGR":"0","ADTM":"2019-11-07 23:12:09","ADY":22,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-63","SUBJID":"id-63","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.80483,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-16 23:12:09","TRT01SDTM":"2019-10-16 23:12:09","AP01SDTM":"2019-10-16 23:12:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1927,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.09798,"AVALU":"mg/L","BASE2":11.49253,"BASE":9.09798,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.39455,"PCHG2":-20.83572,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-06 23:12:09","ADY":51,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-63","SUBJID":"id-63","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.80483,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-16 23:12:09","TRT01SDTM":"2019-10-16 23:12:09","AP01SDTM":"2019-10-16 23:12:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2321,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.67793,"AVALU":"mg/L","BASE2":11.49253,"BASE":9.09798,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.81461,"PCHG2":-24.49076,"CHG":-0.42006,"PCHG":-4.61704,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-03 23:12:09","ADY":79,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-63","SUBJID":"id-63","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.80483,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-16 23:12:09","TRT01SDTM":"2019-10-16 23:12:09","AP01SDTM":"2019-10-16 23:12:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3077,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.06802,"AVALU":"mg/L","BASE2":11.49253,"BASE":9.09798,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.42452,"PCHG2":-21.09646,"CHG":-0.02997,"PCHG":-0.32937,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-14 23:12:09","ADY":90,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-63","SUBJID":"id-63","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.80483,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-16 23:12:09","TRT01SDTM":"2019-10-16 23:12:09","AP01SDTM":"2019-10-16 23:12:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8083,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.42939,"AVALU":"mg/L","BASE2":11.49253,"BASE":9.09798,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.06315,"PCHG2":-26.65337,"CHG":-0.6686,"PCHG":-7.34884,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-31 23:12:09","ADY":107,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-63","SUBJID":"id-63","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.80483,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-16 23:12:09","TRT01SDTM":"2019-10-16 23:12:09","AP01SDTM":"2019-10-16 23:12:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4577,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.48083,"AVALU":"mg/L","BASE2":11.49253,"BASE":9.09798,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.01171,"PCHG2":-17.50446,"CHG":0.38285,"PCHG":4.20803,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-10 23:12:09","ADY":330,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-63","SUBJID":"id-63","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.80483,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-16 23:12:09","TRT01SDTM":"2019-10-16 23:12:09","AP01SDTM":"2019-10-16 23:12:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8004,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.4063,"AVALU":"mg/L","BASE2":11.49253,"BASE":9.09798,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.08623,"PCHG2":-18.15292,"CHG":0.30832,"PCHG":3.3889,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-04 23:12:09","ADY":689,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-63","SUBJID":"id-63","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.80483,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-16 23:12:09","TRT01SDTM":"2019-10-16 23:12:09","AP01SDTM":"2019-10-16 23:12:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6046,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92134,"AVALU":"g/L","BASE2":2.92134,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-07 23:12:09","ADY":22,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-63","SUBJID":"id-63","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.80483,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-16 23:12:09","TRT01SDTM":"2019-10-16 23:12:09","AP01SDTM":"2019-10-16 23:12:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6972,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97287,"AVALU":"g/L","BASE2":2.92134,"BASE":2.97287,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.05153,"PCHG2":1.76394,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-06 23:12:09","ADY":51,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-63","SUBJID":"id-63","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.80483,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-16 23:12:09","TRT01SDTM":"2019-10-16 23:12:09","AP01SDTM":"2019-10-16 23:12:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6594,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03394,"AVALU":"g/L","BASE2":2.92134,"BASE":2.97287,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11261,"PCHG2":3.85468,"CHG":0.06108,"PCHG":2.0545,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-01-03 23:12:09","ADY":79,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-63","SUBJID":"id-63","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.80483,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-16 23:12:09","TRT01SDTM":"2019-10-16 23:12:09","AP01SDTM":"2019-10-16 23:12:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":441,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.08983,"AVALU":"g/L","BASE2":2.92134,"BASE":2.97287,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16849,"PCHG2":5.76764,"CHG":0.11696,"PCHG":3.93431,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-01-14 23:12:09","ADY":90,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-63","SUBJID":"id-63","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.80483,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-16 23:12:09","TRT01SDTM":"2019-10-16 23:12:09","AP01SDTM":"2019-10-16 23:12:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3371,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91766,"AVALU":"g/L","BASE2":2.92134,"BASE":2.97287,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00368,"PCHG2":-0.12594,"CHG":-0.05521,"PCHG":-1.85711,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-31 23:12:09","ADY":107,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-63","SUBJID":"id-63","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.80483,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-16 23:12:09","TRT01SDTM":"2019-10-16 23:12:09","AP01SDTM":"2019-10-16 23:12:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3344,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98478,"AVALU":"g/L","BASE2":2.92134,"BASE":2.97287,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06345,"PCHG2":2.17186,"CHG":0.01192,"PCHG":0.40085,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-10 23:12:09","ADY":330,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-63","SUBJID":"id-63","SITEID":"CHN-11","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.80483,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-16 23:12:09","TRT01SDTM":"2019-10-16 23:12:09","AP01SDTM":"2019-10-16 23:12:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5342,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85568,"AVALU":"g/L","BASE2":2.92134,"BASE":2.97287,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06565,"PCHG2":-2.24731,"CHG":-0.11718,"PCHG":-3.94171,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-04 23:12:09","ADY":689,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-75","SUBJID":"id-75","SITEID":"CHN-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.61263,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-06","TRTSDTM":"2020-03-09 05:22:03","TRTEDTM":"2023-03-09 23:22:03","TRT01SDTM":"2020-03-09 05:22:03","TRT01EDTM":"2022-03-09 17:22:03","TRT02SDTM":"2022-03-09 17:22:03","TRT02EDTM":"2023-03-09 23:22:03","AP01SDTM":"2020-03-09 05:22:03","AP01EDTM":"2022-03-09 17:22:03","AP02SDTM":"2022-03-09 17:22:03","AP02EDTM":"2023-03-09 23:22:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4126,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.19745,"AVALU":"U/L","BASE2":33.19745,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-25 05:22:03","ADY":77,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-75","SUBJID":"id-75","SITEID":"CHN-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.61263,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-06","TRTSDTM":"2020-03-09 05:22:03","TRTEDTM":"2023-03-09 23:22:03","TRT01SDTM":"2020-03-09 05:22:03","TRT01EDTM":"2022-03-09 17:22:03","TRT02SDTM":"2022-03-09 17:22:03","TRT02EDTM":"2023-03-09 23:22:03","AP01SDTM":"2020-03-09 05:22:03","AP01EDTM":"2022-03-09 17:22:03","AP02SDTM":"2022-03-09 17:22:03","AP02EDTM":"2023-03-09 23:22:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4523,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.8502,"AVALU":"U/L","BASE2":33.19745,"BASE":16.8502,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-16.34725,"PCHG2":-49.2425,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-04 05:22:03","ADY":148,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-75","SUBJID":"id-75","SITEID":"CHN-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.61263,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-06","TRTSDTM":"2020-03-09 05:22:03","TRTEDTM":"2023-03-09 23:22:03","TRT01SDTM":"2020-03-09 05:22:03","TRT01EDTM":"2022-03-09 17:22:03","TRT02SDTM":"2022-03-09 17:22:03","TRT02EDTM":"2023-03-09 23:22:03","AP01SDTM":"2020-03-09 05:22:03","AP01EDTM":"2022-03-09 17:22:03","AP02SDTM":"2022-03-09 17:22:03","AP02EDTM":"2023-03-09 23:22:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7146,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.41587,"AVALU":"U/L","BASE2":33.19745,"BASE":16.8502,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.78158,"PCHG2":-29.46486,"CHG":6.56567,"PCHG":38.96496,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-10 05:22:03","ADY":550,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-75","SUBJID":"id-75","SITEID":"CHN-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.61263,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-06","TRTSDTM":"2020-03-09 05:22:03","TRTEDTM":"2023-03-09 23:22:03","TRT01SDTM":"2020-03-09 05:22:03","TRT01EDTM":"2022-03-09 17:22:03","TRT02SDTM":"2022-03-09 17:22:03","TRT02EDTM":"2023-03-09 23:22:03","AP01SDTM":"2020-03-09 05:22:03","AP01EDTM":"2022-03-09 17:22:03","AP02SDTM":"2022-03-09 17:22:03","AP02EDTM":"2023-03-09 23:22:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2543,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.98681,"AVALU":"U/L","BASE2":33.19745,"BASE":16.8502,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.21064,"PCHG2":-27.74501,"CHG":7.13662,"PCHG":42.35332,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-14 05:22:03","ADY":584,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-75","SUBJID":"id-75","SITEID":"CHN-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.61263,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-06","TRTSDTM":"2020-03-09 05:22:03","TRTEDTM":"2023-03-09 23:22:03","TRT01SDTM":"2020-03-09 05:22:03","TRT01EDTM":"2022-03-09 17:22:03","TRT02SDTM":"2022-03-09 17:22:03","TRT02EDTM":"2023-03-09 23:22:03","AP01SDTM":"2020-03-09 05:22:03","AP01EDTM":"2022-03-09 17:22:03","AP02SDTM":"2022-03-09 17:22:03","AP02EDTM":"2023-03-09 23:22:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":695,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.65439,"AVALU":"U/L","BASE2":33.19745,"BASE":16.8502,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-19.54306,"PCHG2":-58.86917,"CHG":-3.19581,"PCHG":-18.966,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-27 05:22:03","ADY":658,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-75","SUBJID":"id-75","SITEID":"CHN-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.61263,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-06","TRTSDTM":"2020-03-09 05:22:03","TRTEDTM":"2023-03-09 23:22:03","TRT01SDTM":"2020-03-09 05:22:03","TRT01EDTM":"2022-03-09 17:22:03","TRT02SDTM":"2022-03-09 17:22:03","TRT02EDTM":"2023-03-09 23:22:03","AP01SDTM":"2020-03-09 05:22:03","AP01EDTM":"2022-03-09 17:22:03","AP02SDTM":"2022-03-09 17:22:03","AP02EDTM":"2023-03-09 23:22:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4418,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.89083,"AVALU":"U/L","BASE2":33.19745,"BASE":16.8502,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-28.30663,"PCHG2":-85.26747,"CHG":-11.95937,"PCHG":-70.97467,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-04-04 05:22:03","ADY":756,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-75","SUBJID":"id-75","SITEID":"CHN-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.61263,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-06","TRTSDTM":"2020-03-09 05:22:03","TRTEDTM":"2023-03-09 23:22:03","TRT01SDTM":"2020-03-09 05:22:03","TRT01EDTM":"2022-03-09 17:22:03","TRT02SDTM":"2022-03-09 17:22:03","TRT02EDTM":"2023-03-09 23:22:03","AP01SDTM":"2020-03-09 05:22:03","AP01EDTM":"2022-03-09 17:22:03","AP02SDTM":"2022-03-09 17:22:03","AP02EDTM":"2023-03-09 23:22:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3688,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.45149,"AVALU":"U/L","BASE2":33.19745,"BASE":16.8502,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-30.74596,"PCHG2":-92.61542,"CHG":-14.3987,"PCHG":-85.45125,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-06-19 05:22:03","ADY":832,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-75","SUBJID":"id-75","SITEID":"CHN-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.61263,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-06","TRTSDTM":"2020-03-09 05:22:03","TRTEDTM":"2023-03-09 23:22:03","TRT01SDTM":"2020-03-09 05:22:03","TRT01EDTM":"2022-03-09 17:22:03","TRT02SDTM":"2022-03-09 17:22:03","TRT02EDTM":"2023-03-09 23:22:03","AP01SDTM":"2020-03-09 05:22:03","AP01EDTM":"2022-03-09 17:22:03","AP02SDTM":"2022-03-09 17:22:03","AP02EDTM":"2023-03-09 23:22:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":665,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.17067,"AVALU":"mg/L","BASE2":9.17067,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-25 05:22:03","ADY":77,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-75","SUBJID":"id-75","SITEID":"CHN-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.61263,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-06","TRTSDTM":"2020-03-09 05:22:03","TRTEDTM":"2023-03-09 23:22:03","TRT01SDTM":"2020-03-09 05:22:03","TRT01EDTM":"2022-03-09 17:22:03","TRT02SDTM":"2022-03-09 17:22:03","TRT02EDTM":"2023-03-09 23:22:03","AP01SDTM":"2020-03-09 05:22:03","AP01EDTM":"2022-03-09 17:22:03","AP02SDTM":"2022-03-09 17:22:03","AP02EDTM":"2023-03-09 23:22:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5777,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.31075,"AVALU":"mg/L","BASE2":9.17067,"BASE":9.31075,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.14008,"PCHG2":1.52749,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-04 05:22:03","ADY":148,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-75","SUBJID":"id-75","SITEID":"CHN-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.61263,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-06","TRTSDTM":"2020-03-09 05:22:03","TRTEDTM":"2023-03-09 23:22:03","TRT01SDTM":"2020-03-09 05:22:03","TRT01EDTM":"2022-03-09 17:22:03","TRT02SDTM":"2022-03-09 17:22:03","TRT02EDTM":"2023-03-09 23:22:03","AP01SDTM":"2020-03-09 05:22:03","AP01EDTM":"2022-03-09 17:22:03","AP02SDTM":"2022-03-09 17:22:03","AP02EDTM":"2023-03-09 23:22:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4288,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.40651,"AVALU":"mg/L","BASE2":9.17067,"BASE":9.31075,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.76416,"PCHG2":-8.3327,"CHG":-0.90425,"PCHG":-9.71184,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-10 05:22:03","ADY":550,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-75","SUBJID":"id-75","SITEID":"CHN-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.61263,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-06","TRTSDTM":"2020-03-09 05:22:03","TRTEDTM":"2023-03-09 23:22:03","TRT01SDTM":"2020-03-09 05:22:03","TRT01EDTM":"2022-03-09 17:22:03","TRT02SDTM":"2022-03-09 17:22:03","TRT02EDTM":"2023-03-09 23:22:03","AP01SDTM":"2020-03-09 05:22:03","AP01EDTM":"2022-03-09 17:22:03","AP02SDTM":"2022-03-09 17:22:03","AP02EDTM":"2023-03-09 23:22:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4095,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.1733,"AVALU":"mg/L","BASE2":9.17067,"BASE":9.31075,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00263,"PCHG2":0.02865,"CHG":-0.13745,"PCHG":-1.47629,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-14 05:22:03","ADY":584,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-75","SUBJID":"id-75","SITEID":"CHN-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.61263,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-06","TRTSDTM":"2020-03-09 05:22:03","TRTEDTM":"2023-03-09 23:22:03","TRT01SDTM":"2020-03-09 05:22:03","TRT01EDTM":"2022-03-09 17:22:03","TRT02SDTM":"2022-03-09 17:22:03","TRT02EDTM":"2023-03-09 23:22:03","AP01SDTM":"2020-03-09 05:22:03","AP01EDTM":"2022-03-09 17:22:03","AP02SDTM":"2022-03-09 17:22:03","AP02EDTM":"2023-03-09 23:22:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3171,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.92606,"AVALU":"mg/L","BASE2":9.17067,"BASE":9.31075,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.24462,"PCHG2":-2.66738,"CHG":-0.3847,"PCHG":-4.13176,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-27 05:22:03","ADY":658,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-75","SUBJID":"id-75","SITEID":"CHN-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.61263,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-06","TRTSDTM":"2020-03-09 05:22:03","TRTEDTM":"2023-03-09 23:22:03","TRT01SDTM":"2020-03-09 05:22:03","TRT01EDTM":"2022-03-09 17:22:03","TRT02SDTM":"2022-03-09 17:22:03","TRT02EDTM":"2023-03-09 23:22:03","AP01SDTM":"2020-03-09 05:22:03","AP01EDTM":"2022-03-09 17:22:03","AP02SDTM":"2022-03-09 17:22:03","AP02EDTM":"2023-03-09 23:22:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5313,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.24629,"AVALU":"mg/L","BASE2":9.17067,"BASE":9.31075,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.92439,"PCHG2":-10.0798,"CHG":-1.06447,"PCHG":-11.43266,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-04 05:22:03","ADY":756,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-75","SUBJID":"id-75","SITEID":"CHN-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.61263,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-06","TRTSDTM":"2020-03-09 05:22:03","TRTEDTM":"2023-03-09 23:22:03","TRT01SDTM":"2020-03-09 05:22:03","TRT01EDTM":"2022-03-09 17:22:03","TRT02SDTM":"2022-03-09 17:22:03","TRT02EDTM":"2023-03-09 23:22:03","AP01SDTM":"2020-03-09 05:22:03","AP01EDTM":"2022-03-09 17:22:03","AP02SDTM":"2022-03-09 17:22:03","AP02EDTM":"2023-03-09 23:22:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2262,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.97577,"AVALU":"mg/L","BASE2":9.17067,"BASE":9.31075,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1949,"PCHG2":-2.1253,"CHG":-0.33499,"PCHG":-3.59783,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-19 05:22:03","ADY":832,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-75","SUBJID":"id-75","SITEID":"CHN-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.61263,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-06","TRTSDTM":"2020-03-09 05:22:03","TRTEDTM":"2023-03-09 23:22:03","TRT01SDTM":"2020-03-09 05:22:03","TRT01EDTM":"2022-03-09 17:22:03","TRT02SDTM":"2022-03-09 17:22:03","TRT02EDTM":"2023-03-09 23:22:03","AP01SDTM":"2020-03-09 05:22:03","AP01EDTM":"2022-03-09 17:22:03","AP02SDTM":"2022-03-09 17:22:03","AP02EDTM":"2023-03-09 23:22:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7688,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88373,"AVALU":"g/L","BASE2":2.88373,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-05-25 05:22:03","ADY":77,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-75","SUBJID":"id-75","SITEID":"CHN-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.61263,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-06","TRTSDTM":"2020-03-09 05:22:03","TRTEDTM":"2023-03-09 23:22:03","TRT01SDTM":"2020-03-09 05:22:03","TRT01EDTM":"2022-03-09 17:22:03","TRT02SDTM":"2022-03-09 17:22:03","TRT02EDTM":"2023-03-09 23:22:03","AP01SDTM":"2020-03-09 05:22:03","AP01EDTM":"2022-03-09 17:22:03","AP02SDTM":"2022-03-09 17:22:03","AP02EDTM":"2023-03-09 23:22:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6516,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00202,"AVALU":"g/L","BASE2":2.88373,"BASE":3.00202,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.11829,"PCHG2":4.10192,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2020-08-04 05:22:03","ADY":148,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-75","SUBJID":"id-75","SITEID":"CHN-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.61263,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-06","TRTSDTM":"2020-03-09 05:22:03","TRTEDTM":"2023-03-09 23:22:03","TRT01SDTM":"2020-03-09 05:22:03","TRT01EDTM":"2022-03-09 17:22:03","TRT02SDTM":"2022-03-09 17:22:03","TRT02EDTM":"2023-03-09 23:22:03","AP01SDTM":"2020-03-09 05:22:03","AP01EDTM":"2022-03-09 17:22:03","AP02SDTM":"2022-03-09 17:22:03","AP02EDTM":"2023-03-09 23:22:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5733,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8211,"AVALU":"g/L","BASE2":2.88373,"BASE":3.00202,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06264,"PCHG2":-2.17201,"CHG":-0.18092,"PCHG":-6.02672,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-09-10 05:22:03","ADY":550,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-75","SUBJID":"id-75","SITEID":"CHN-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.61263,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-06","TRTSDTM":"2020-03-09 05:22:03","TRTEDTM":"2023-03-09 23:22:03","TRT01SDTM":"2020-03-09 05:22:03","TRT01EDTM":"2022-03-09 17:22:03","TRT02SDTM":"2022-03-09 17:22:03","TRT02EDTM":"2023-03-09 23:22:03","AP01SDTM":"2020-03-09 05:22:03","AP01EDTM":"2022-03-09 17:22:03","AP02SDTM":"2022-03-09 17:22:03","AP02EDTM":"2023-03-09 23:22:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2613,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86574,"AVALU":"g/L","BASE2":2.88373,"BASE":3.00202,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01799,"PCHG2":-0.62388,"CHG":-0.13628,"PCHG":-4.53959,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-10-14 05:22:03","ADY":584,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-75","SUBJID":"id-75","SITEID":"CHN-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.61263,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-06","TRTSDTM":"2020-03-09 05:22:03","TRTEDTM":"2023-03-09 23:22:03","TRT01SDTM":"2020-03-09 05:22:03","TRT01EDTM":"2022-03-09 17:22:03","TRT02SDTM":"2022-03-09 17:22:03","TRT02EDTM":"2023-03-09 23:22:03","AP01SDTM":"2020-03-09 05:22:03","AP01EDTM":"2022-03-09 17:22:03","AP02SDTM":"2022-03-09 17:22:03","AP02EDTM":"2023-03-09 23:22:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2935,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93891,"AVALU":"g/L","BASE2":2.88373,"BASE":3.00202,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05517,"PCHG2":1.91328,"CHG":-0.06311,"PCHG":-2.1024,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-12-27 05:22:03","ADY":658,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-75","SUBJID":"id-75","SITEID":"CHN-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.61263,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-06","TRTSDTM":"2020-03-09 05:22:03","TRTEDTM":"2023-03-09 23:22:03","TRT01SDTM":"2020-03-09 05:22:03","TRT01EDTM":"2022-03-09 17:22:03","TRT02SDTM":"2022-03-09 17:22:03","TRT02EDTM":"2023-03-09 23:22:03","AP01SDTM":"2020-03-09 05:22:03","AP01EDTM":"2022-03-09 17:22:03","AP02SDTM":"2022-03-09 17:22:03","AP02EDTM":"2023-03-09 23:22:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5229,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87283,"AVALU":"g/L","BASE2":2.88373,"BASE":3.00202,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0109,"PCHG2":-0.37799,"CHG":-0.12919,"PCHG":-4.30339,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-04-04 05:22:03","ADY":756,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-75","SUBJID":"id-75","SITEID":"CHN-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.61263,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-06","TRTSDTM":"2020-03-09 05:22:03","TRTEDTM":"2023-03-09 23:22:03","TRT01SDTM":"2020-03-09 05:22:03","TRT01EDTM":"2022-03-09 17:22:03","TRT02SDTM":"2022-03-09 17:22:03","TRT02EDTM":"2023-03-09 23:22:03","AP01SDTM":"2020-03-09 05:22:03","AP01EDTM":"2022-03-09 17:22:03","AP02SDTM":"2022-03-09 17:22:03","AP02EDTM":"2023-03-09 23:22:03","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1573,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93057,"AVALU":"g/L","BASE2":2.88373,"BASE":3.00202,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04684,"PCHG2":1.62415,"CHG":-0.07145,"PCHG":-2.38014,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-06-19 05:22:03","ADY":832,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-88","SUBJID":"id-88","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.36809,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-22","TRTSDTM":"2019-05-22 23:38:16","TRTEDTM":"2022-05-22 17:38:16","TRT01SDTM":"2019-05-22 23:38:16","TRT01EDTM":"2021-05-22 11:38:16","TRT02SDTM":"2021-05-22 11:38:16","TRT02EDTM":"2022-05-22 17:38:16","AP01SDTM":"2019-05-22 23:38:16","AP01EDTM":"2021-05-22 11:38:16","AP02SDTM":"2021-05-22 11:38:16","AP02EDTM":"2022-05-22 17:38:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-22","EOSDY":1096,"LSTALVDT":"2022-06-14","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3444,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.92505,"AVALU":"U/L","BASE2":10.92505,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-06-27 23:38:16","ADY":36,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-88","SUBJID":"id-88","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.36809,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-22","TRTSDTM":"2019-05-22 23:38:16","TRTEDTM":"2022-05-22 17:38:16","TRT01SDTM":"2019-05-22 23:38:16","TRT01EDTM":"2021-05-22 11:38:16","TRT02SDTM":"2021-05-22 11:38:16","TRT02EDTM":"2022-05-22 17:38:16","AP01SDTM":"2019-05-22 23:38:16","AP01EDTM":"2021-05-22 11:38:16","AP02SDTM":"2021-05-22 11:38:16","AP02EDTM":"2022-05-22 17:38:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-22","EOSDY":1096,"LSTALVDT":"2022-06-14","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3965,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.34868,"AVALU":"U/L","BASE2":10.92505,"BASE":14.34868,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":3.42364,"PCHG2":31.33749,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-18 23:38:16","ADY":210,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-88","SUBJID":"id-88","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.36809,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-22","TRTSDTM":"2019-05-22 23:38:16","TRTEDTM":"2022-05-22 17:38:16","TRT01SDTM":"2019-05-22 23:38:16","TRT01EDTM":"2021-05-22 11:38:16","TRT02SDTM":"2021-05-22 11:38:16","TRT02EDTM":"2022-05-22 17:38:16","AP01SDTM":"2019-05-22 23:38:16","AP01EDTM":"2021-05-22 11:38:16","AP02SDTM":"2021-05-22 11:38:16","AP02EDTM":"2022-05-22 17:38:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-22","EOSDY":1096,"LSTALVDT":"2022-06-14","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1323,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.76216,"AVALU":"U/L","BASE2":10.92505,"BASE":14.34868,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":17.83711,"PCHG2":163.26805,"CHG":14.41348,"PCHG":100.45157,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-30 23:38:16","ADY":313,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-88","SUBJID":"id-88","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.36809,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-22","TRTSDTM":"2019-05-22 23:38:16","TRTEDTM":"2022-05-22 17:38:16","TRT01SDTM":"2019-05-22 23:38:16","TRT01EDTM":"2021-05-22 11:38:16","TRT02SDTM":"2021-05-22 11:38:16","TRT02EDTM":"2022-05-22 17:38:16","AP01SDTM":"2019-05-22 23:38:16","AP01EDTM":"2021-05-22 11:38:16","AP02SDTM":"2021-05-22 11:38:16","AP02EDTM":"2022-05-22 17:38:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-22","EOSDY":1096,"LSTALVDT":"2022-06-14","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2786,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.8871,"AVALU":"U/L","BASE2":10.92505,"BASE":14.34868,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.96205,"PCHG2":27.1125,"CHG":-0.46158,"PCHG":-3.2169,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-08 23:38:16","ADY":566,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-88","SUBJID":"id-88","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.36809,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-22","TRTSDTM":"2019-05-22 23:38:16","TRTEDTM":"2022-05-22 17:38:16","TRT01SDTM":"2019-05-22 23:38:16","TRT01EDTM":"2021-05-22 11:38:16","TRT02SDTM":"2021-05-22 11:38:16","TRT02EDTM":"2022-05-22 17:38:16","AP01SDTM":"2019-05-22 23:38:16","AP01EDTM":"2021-05-22 11:38:16","AP02SDTM":"2021-05-22 11:38:16","AP02EDTM":"2022-05-22 17:38:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-22","EOSDY":1096,"LSTALVDT":"2022-06-14","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6903,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.1028,"AVALU":"U/L","BASE2":10.92505,"BASE":14.34868,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.17775,"PCHG2":166.38603,"CHG":14.75412,"PCHG":102.82559,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-18 23:38:16","ADY":727,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-88","SUBJID":"id-88","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.36809,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-22","TRTSDTM":"2019-05-22 23:38:16","TRTEDTM":"2022-05-22 17:38:16","TRT01SDTM":"2019-05-22 23:38:16","TRT01EDTM":"2021-05-22 11:38:16","TRT02SDTM":"2021-05-22 11:38:16","TRT02EDTM":"2022-05-22 17:38:16","AP01SDTM":"2019-05-22 23:38:16","AP01EDTM":"2021-05-22 11:38:16","AP02SDTM":"2021-05-22 11:38:16","AP02EDTM":"2022-05-22 17:38:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-22","EOSDY":1096,"LSTALVDT":"2022-06-14","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5396,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.82732,"AVALU":"U/L","BASE2":10.92505,"BASE":14.34868,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.90227,"PCHG2":173.01773,"CHG":15.47864,"PCHG":107.87495,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-17 23:38:16","ADY":757,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-88","SUBJID":"id-88","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.36809,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-22","TRTSDTM":"2019-05-22 23:38:16","TRTEDTM":"2022-05-22 17:38:16","TRT01SDTM":"2019-05-22 23:38:16","TRT01EDTM":"2021-05-22 11:38:16","TRT02SDTM":"2021-05-22 11:38:16","TRT02EDTM":"2022-05-22 17:38:16","AP01SDTM":"2019-05-22 23:38:16","AP01EDTM":"2021-05-22 11:38:16","AP02SDTM":"2021-05-22 11:38:16","AP02EDTM":"2022-05-22 17:38:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-22","EOSDY":1096,"LSTALVDT":"2022-06-14","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6502,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.40283,"AVALU":"U/L","BASE2":10.92505,"BASE":14.34868,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.47778,"PCHG2":169.13226,"CHG":15.05415,"PCHG":104.91656,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-02 23:38:16","ADY":925,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-88","SUBJID":"id-88","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.36809,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-22","TRTSDTM":"2019-05-22 23:38:16","TRTEDTM":"2022-05-22 17:38:16","TRT01SDTM":"2019-05-22 23:38:16","TRT01EDTM":"2021-05-22 11:38:16","TRT02SDTM":"2021-05-22 11:38:16","TRT02EDTM":"2022-05-22 17:38:16","AP01SDTM":"2019-05-22 23:38:16","AP01EDTM":"2021-05-22 11:38:16","AP02SDTM":"2021-05-22 11:38:16","AP02EDTM":"2022-05-22 17:38:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-22","EOSDY":1096,"LSTALVDT":"2022-06-14","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1374,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.04266,"AVALU":"mg/L","BASE2":8.04266,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-06-27 23:38:16","ADY":36,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-88","SUBJID":"id-88","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.36809,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-22","TRTSDTM":"2019-05-22 23:38:16","TRTEDTM":"2022-05-22 17:38:16","TRT01SDTM":"2019-05-22 23:38:16","TRT01EDTM":"2021-05-22 11:38:16","TRT02SDTM":"2021-05-22 11:38:16","TRT02EDTM":"2022-05-22 17:38:16","AP01SDTM":"2019-05-22 23:38:16","AP01EDTM":"2021-05-22 11:38:16","AP02SDTM":"2021-05-22 11:38:16","AP02EDTM":"2022-05-22 17:38:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-22","EOSDY":1096,"LSTALVDT":"2022-06-14","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8126,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.37724,"AVALU":"mg/L","BASE2":8.04266,"BASE":9.37724,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.33458,"PCHG2":16.59373,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-18 23:38:16","ADY":210,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-88","SUBJID":"id-88","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.36809,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-22","TRTSDTM":"2019-05-22 23:38:16","TRTEDTM":"2022-05-22 17:38:16","TRT01SDTM":"2019-05-22 23:38:16","TRT01EDTM":"2021-05-22 11:38:16","TRT02SDTM":"2021-05-22 11:38:16","TRT02EDTM":"2022-05-22 17:38:16","AP01SDTM":"2019-05-22 23:38:16","AP01EDTM":"2021-05-22 11:38:16","AP02SDTM":"2021-05-22 11:38:16","AP02EDTM":"2022-05-22 17:38:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-22","EOSDY":1096,"LSTALVDT":"2022-06-14","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3977,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.71166,"AVALU":"mg/L","BASE2":8.04266,"BASE":9.37724,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.66899,"PCHG2":20.75171,"CHG":0.33441,"PCHG":3.56621,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-30 23:38:16","ADY":313,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-88","SUBJID":"id-88","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.36809,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-22","TRTSDTM":"2019-05-22 23:38:16","TRTEDTM":"2022-05-22 17:38:16","TRT01SDTM":"2019-05-22 23:38:16","TRT01EDTM":"2021-05-22 11:38:16","TRT02SDTM":"2021-05-22 11:38:16","TRT02EDTM":"2022-05-22 17:38:16","AP01SDTM":"2019-05-22 23:38:16","AP01EDTM":"2021-05-22 11:38:16","AP02SDTM":"2021-05-22 11:38:16","AP02EDTM":"2022-05-22 17:38:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-22","EOSDY":1096,"LSTALVDT":"2022-06-14","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5264,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.58397,"AVALU":"mg/L","BASE2":8.04266,"BASE":9.37724,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.5413,"PCHG2":19.16409,"CHG":0.20673,"PCHG":2.20455,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-08 23:38:16","ADY":566,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-88","SUBJID":"id-88","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.36809,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-22","TRTSDTM":"2019-05-22 23:38:16","TRTEDTM":"2022-05-22 17:38:16","TRT01SDTM":"2019-05-22 23:38:16","TRT01EDTM":"2021-05-22 11:38:16","TRT02SDTM":"2021-05-22 11:38:16","TRT02EDTM":"2022-05-22 17:38:16","AP01SDTM":"2019-05-22 23:38:16","AP01EDTM":"2021-05-22 11:38:16","AP02SDTM":"2021-05-22 11:38:16","AP02EDTM":"2022-05-22 17:38:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-22","EOSDY":1096,"LSTALVDT":"2022-06-14","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1024,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.22816,"AVALU":"mg/L","BASE2":8.04266,"BASE":9.37724,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1855,"PCHG2":2.30643,"CHG":-1.14908,"PCHG":-12.25392,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-18 23:38:16","ADY":727,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-88","SUBJID":"id-88","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.36809,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-22","TRTSDTM":"2019-05-22 23:38:16","TRTEDTM":"2022-05-22 17:38:16","TRT01SDTM":"2019-05-22 23:38:16","TRT01EDTM":"2021-05-22 11:38:16","TRT02SDTM":"2021-05-22 11:38:16","TRT02EDTM":"2022-05-22 17:38:16","AP01SDTM":"2019-05-22 23:38:16","AP01EDTM":"2021-05-22 11:38:16","AP02SDTM":"2021-05-22 11:38:16","AP02EDTM":"2022-05-22 17:38:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-22","EOSDY":1096,"LSTALVDT":"2022-06-14","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5315,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.96592,"AVALU":"mg/L","BASE2":8.04266,"BASE":9.37724,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07674,"PCHG2":-0.95418,"CHG":-1.41132,"PCHG":-15.05047,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-06-17 23:38:16","ADY":757,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-88","SUBJID":"id-88","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.36809,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-22","TRTSDTM":"2019-05-22 23:38:16","TRTEDTM":"2022-05-22 17:38:16","TRT01SDTM":"2019-05-22 23:38:16","TRT01EDTM":"2021-05-22 11:38:16","TRT02SDTM":"2021-05-22 11:38:16","TRT02EDTM":"2022-05-22 17:38:16","AP01SDTM":"2019-05-22 23:38:16","AP01EDTM":"2021-05-22 11:38:16","AP02SDTM":"2021-05-22 11:38:16","AP02EDTM":"2022-05-22 17:38:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-22","EOSDY":1096,"LSTALVDT":"2022-06-14","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6179,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.98099,"AVALU":"mg/L","BASE2":8.04266,"BASE":9.37724,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06167,"PCHG2":-0.76685,"CHG":-1.39625,"PCHG":-14.8898,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-12-02 23:38:16","ADY":925,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-88","SUBJID":"id-88","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.36809,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-22","TRTSDTM":"2019-05-22 23:38:16","TRTEDTM":"2022-05-22 17:38:16","TRT01SDTM":"2019-05-22 23:38:16","TRT01EDTM":"2021-05-22 11:38:16","TRT02SDTM":"2021-05-22 11:38:16","TRT02EDTM":"2022-05-22 17:38:16","AP01SDTM":"2019-05-22 23:38:16","AP01EDTM":"2021-05-22 11:38:16","AP02SDTM":"2021-05-22 11:38:16","AP02EDTM":"2022-05-22 17:38:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-22","EOSDY":1096,"LSTALVDT":"2022-06-14","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5012,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77453,"AVALU":"g/L","BASE2":2.77453,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-06-27 23:38:16","ADY":36,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-88","SUBJID":"id-88","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.36809,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-22","TRTSDTM":"2019-05-22 23:38:16","TRTEDTM":"2022-05-22 17:38:16","TRT01SDTM":"2019-05-22 23:38:16","TRT01EDTM":"2021-05-22 11:38:16","TRT02SDTM":"2021-05-22 11:38:16","TRT02EDTM":"2022-05-22 17:38:16","AP01SDTM":"2019-05-22 23:38:16","AP01EDTM":"2021-05-22 11:38:16","AP02SDTM":"2021-05-22 11:38:16","AP02EDTM":"2022-05-22 17:38:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-22","EOSDY":1096,"LSTALVDT":"2022-06-14","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5238,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89407,"AVALU":"g/L","BASE2":2.77453,"BASE":2.89407,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.11954,"PCHG2":4.30863,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-18 23:38:16","ADY":210,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-88","SUBJID":"id-88","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.36809,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-22","TRTSDTM":"2019-05-22 23:38:16","TRTEDTM":"2022-05-22 17:38:16","TRT01SDTM":"2019-05-22 23:38:16","TRT01EDTM":"2021-05-22 11:38:16","TRT02SDTM":"2021-05-22 11:38:16","TRT02EDTM":"2022-05-22 17:38:16","AP01SDTM":"2019-05-22 23:38:16","AP01EDTM":"2021-05-22 11:38:16","AP02SDTM":"2021-05-22 11:38:16","AP02EDTM":"2022-05-22 17:38:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-22","EOSDY":1096,"LSTALVDT":"2022-06-14","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2304,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83422,"AVALU":"g/L","BASE2":2.77453,"BASE":2.89407,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05969,"PCHG2":2.15125,"CHG":-0.05986,"PCHG":-2.06827,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-30 23:38:16","ADY":313,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-88","SUBJID":"id-88","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.36809,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-22","TRTSDTM":"2019-05-22 23:38:16","TRTEDTM":"2022-05-22 17:38:16","TRT01SDTM":"2019-05-22 23:38:16","TRT01EDTM":"2021-05-22 11:38:16","TRT02SDTM":"2021-05-22 11:38:16","TRT02EDTM":"2022-05-22 17:38:16","AP01SDTM":"2019-05-22 23:38:16","AP01EDTM":"2021-05-22 11:38:16","AP02SDTM":"2021-05-22 11:38:16","AP02EDTM":"2022-05-22 17:38:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-22","EOSDY":1096,"LSTALVDT":"2022-06-14","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6318,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8732,"AVALU":"g/L","BASE2":2.77453,"BASE":2.89407,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09867,"PCHG2":3.55619,"CHG":-0.02088,"PCHG":-0.72136,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-08 23:38:16","ADY":566,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-88","SUBJID":"id-88","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.36809,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-22","TRTSDTM":"2019-05-22 23:38:16","TRTEDTM":"2022-05-22 17:38:16","TRT01SDTM":"2019-05-22 23:38:16","TRT01EDTM":"2021-05-22 11:38:16","TRT02SDTM":"2021-05-22 11:38:16","TRT02EDTM":"2022-05-22 17:38:16","AP01SDTM":"2019-05-22 23:38:16","AP01EDTM":"2021-05-22 11:38:16","AP02SDTM":"2021-05-22 11:38:16","AP02EDTM":"2022-05-22 17:38:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-22","EOSDY":1096,"LSTALVDT":"2022-06-14","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5808,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84813,"AVALU":"g/L","BASE2":2.77453,"BASE":2.89407,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0736,"PCHG2":2.65263,"CHG":-0.04595,"PCHG":-1.5876,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-18 23:38:16","ADY":727,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-88","SUBJID":"id-88","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.36809,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-22","TRTSDTM":"2019-05-22 23:38:16","TRTEDTM":"2022-05-22 17:38:16","TRT01SDTM":"2019-05-22 23:38:16","TRT01EDTM":"2021-05-22 11:38:16","TRT02SDTM":"2021-05-22 11:38:16","TRT02EDTM":"2022-05-22 17:38:16","AP01SDTM":"2019-05-22 23:38:16","AP01EDTM":"2021-05-22 11:38:16","AP02SDTM":"2021-05-22 11:38:16","AP02EDTM":"2022-05-22 17:38:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-22","EOSDY":1096,"LSTALVDT":"2022-06-14","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4532,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8899,"AVALU":"g/L","BASE2":2.77453,"BASE":2.89407,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11537,"PCHG2":4.15826,"CHG":-0.00417,"PCHG":-0.14416,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-17 23:38:16","ADY":757,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-88","SUBJID":"id-88","SITEID":"CHN-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.36809,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-22","TRTSDTM":"2019-05-22 23:38:16","TRTEDTM":"2022-05-22 17:38:16","TRT01SDTM":"2019-05-22 23:38:16","TRT01EDTM":"2021-05-22 11:38:16","TRT02SDTM":"2021-05-22 11:38:16","TRT02EDTM":"2022-05-22 17:38:16","AP01SDTM":"2019-05-22 23:38:16","AP01EDTM":"2021-05-22 11:38:16","AP02SDTM":"2021-05-22 11:38:16","AP02EDTM":"2022-05-22 17:38:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-22","EOSDY":1096,"LSTALVDT":"2022-06-14","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6966,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99425,"AVALU":"g/L","BASE2":2.77453,"BASE":2.89407,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.21972,"PCHG2":7.91911,"CHG":0.10017,"PCHG":3.46134,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-02 23:38:16","ADY":925,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-90","SUBJID":"id-90","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.2096,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 21:28:15","TRT01SDTM":"2019-12-31 21:28:15","AP01SDTM":"2019-12-31 21:28:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5895,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.44973,"AVALU":"U/L","BASE2":15.44973,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-4","ADTM":"2020-01-05 21:28:15","ADY":5,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-90","SUBJID":"id-90","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.2096,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 21:28:15","TRT01SDTM":"2019-12-31 21:28:15","AP01SDTM":"2019-12-31 21:28:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4516,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.86831,"AVALU":"U/L","BASE2":15.44973,"BASE":6.86831,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-8.58142,"PCHG2":-55.54412,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-4","BTOXGR":"-4","ADTM":"2020-03-03 21:28:15","ADY":63,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-90","SUBJID":"id-90","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.2096,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 21:28:15","TRT01SDTM":"2019-12-31 21:28:15","AP01SDTM":"2019-12-31 21:28:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6656,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.17101,"AVALU":"U/L","BASE2":15.44973,"BASE":6.86831,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.27872,"PCHG2":-66.53007,"CHG":-1.6973,"PCHG":-24.71204,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-2","BTOXGR":"-4","ADTM":"2020-07-31 21:28:15","ADY":213,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-90","SUBJID":"id-90","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.2096,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 21:28:15","TRT01SDTM":"2019-12-31 21:28:15","AP01SDTM":"2019-12-31 21:28:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7452,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.8649,"AVALU":"U/L","BASE2":15.44973,"BASE":6.86831,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.41518,"PCHG2":119.19416,"CHG":26.99659,"PCHG":393.05996,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2020-09-22 21:28:15","ADY":266,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-90","SUBJID":"id-90","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.2096,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 21:28:15","TRT01SDTM":"2019-12-31 21:28:15","AP01SDTM":"2019-12-31 21:28:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6005,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.89821,"AVALU":"U/L","BASE2":15.44973,"BASE":6.86831,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.55152,"PCHG2":-16.51498,"CHG":6.0299,"PCHG":87.79296,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-02-02 21:28:15","ADY":399,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-90","SUBJID":"id-90","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.2096,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 21:28:15","TRT01SDTM":"2019-12-31 21:28:15","AP01SDTM":"2019-12-31 21:28:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2016,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.65911,"AVALU":"U/L","BASE2":15.44973,"BASE":6.86831,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.79062,"PCHG2":-95.73386,"CHG":-6.20921,"PCHG":-90.40366,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-4","ADTM":"2021-12-01 21:28:15","ADY":701,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-90","SUBJID":"id-90","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.2096,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 21:28:15","TRT01SDTM":"2019-12-31 21:28:15","AP01SDTM":"2019-12-31 21:28:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4549,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.6111,"AVALU":"U/L","BASE2":15.44973,"BASE":6.86831,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.16137,"PCHG2":98.13355,"CHG":23.74278,"PCHG":345.68578,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-12-16 21:28:15","ADY":716,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-90","SUBJID":"id-90","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.2096,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 21:28:15","TRT01SDTM":"2019-12-31 21:28:15","AP01SDTM":"2019-12-31 21:28:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7583,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.00737,"AVALU":"mg/L","BASE2":9.00737,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-05 21:28:15","ADY":5,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-90","SUBJID":"id-90","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.2096,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 21:28:15","TRT01SDTM":"2019-12-31 21:28:15","AP01SDTM":"2019-12-31 21:28:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3468,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.64145,"AVALU":"mg/L","BASE2":9.00737,"BASE":9.64145,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.63408,"PCHG2":7.0396,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-03 21:28:15","ADY":63,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-90","SUBJID":"id-90","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.2096,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 21:28:15","TRT01SDTM":"2019-12-31 21:28:15","AP01SDTM":"2019-12-31 21:28:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":855,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.54149,"AVALU":"mg/L","BASE2":9.00737,"BASE":9.64145,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.53412,"PCHG2":17.03189,"CHG":0.90004,"PCHG":9.33513,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-07-31 21:28:15","ADY":213,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-90","SUBJID":"id-90","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.2096,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 21:28:15","TRT01SDTM":"2019-12-31 21:28:15","AP01SDTM":"2019-12-31 21:28:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1247,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.46246,"AVALU":"mg/L","BASE2":9.00737,"BASE":9.64145,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.54491,"PCHG2":-6.0496,"CHG":-1.17899,"PCHG":-12.22838,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-22 21:28:15","ADY":266,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-90","SUBJID":"id-90","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.2096,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 21:28:15","TRT01SDTM":"2019-12-31 21:28:15","AP01SDTM":"2019-12-31 21:28:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4273,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.56561,"AVALU":"mg/L","BASE2":9.00737,"BASE":9.64145,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.55825,"PCHG2":6.19767,"CHG":-0.07584,"PCHG":-0.78657,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-02 21:28:15","ADY":399,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-90","SUBJID":"id-90","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.2096,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 21:28:15","TRT01SDTM":"2019-12-31 21:28:15","AP01SDTM":"2019-12-31 21:28:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3672,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.83904,"AVALU":"mg/L","BASE2":9.00737,"BASE":9.64145,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16833,"PCHG2":-1.86879,"CHG":-0.80241,"PCHG":-8.32252,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-01 21:28:15","ADY":701,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-90","SUBJID":"id-90","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.2096,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 21:28:15","TRT01SDTM":"2019-12-31 21:28:15","AP01SDTM":"2019-12-31 21:28:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1208,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.9133,"AVALU":"mg/L","BASE2":9.00737,"BASE":9.64145,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.90593,"PCHG2":10.05765,"CHG":0.27185,"PCHG":2.81956,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-16 21:28:15","ADY":716,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-90","SUBJID":"id-90","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.2096,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 21:28:15","TRT01SDTM":"2019-12-31 21:28:15","AP01SDTM":"2019-12-31 21:28:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1383,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79039,"AVALU":"g/L","BASE2":2.79039,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-05 21:28:15","ADY":5,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-90","SUBJID":"id-90","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.2096,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 21:28:15","TRT01SDTM":"2019-12-31 21:28:15","AP01SDTM":"2019-12-31 21:28:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":128,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83368,"AVALU":"g/L","BASE2":2.79039,"BASE":2.83368,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.04329,"PCHG2":1.55129,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-03 21:28:15","ADY":63,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-90","SUBJID":"id-90","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.2096,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 21:28:15","TRT01SDTM":"2019-12-31 21:28:15","AP01SDTM":"2019-12-31 21:28:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7017,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96843,"AVALU":"g/L","BASE2":2.79039,"BASE":2.83368,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17804,"PCHG2":6.38046,"CHG":0.13475,"PCHG":4.7554,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-31 21:28:15","ADY":213,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-90","SUBJID":"id-90","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.2096,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 21:28:15","TRT01SDTM":"2019-12-31 21:28:15","AP01SDTM":"2019-12-31 21:28:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2223,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98621,"AVALU":"g/L","BASE2":2.79039,"BASE":2.83368,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.19582,"PCHG2":7.01752,"CHG":0.15253,"PCHG":5.38273,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-22 21:28:15","ADY":266,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-90","SUBJID":"id-90","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.2096,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 21:28:15","TRT01SDTM":"2019-12-31 21:28:15","AP01SDTM":"2019-12-31 21:28:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2886,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86476,"AVALU":"g/L","BASE2":2.79039,"BASE":2.83368,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07436,"PCHG2":2.665,"CHG":0.03108,"PCHG":1.0967,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-02 21:28:15","ADY":399,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-90","SUBJID":"id-90","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.2096,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 21:28:15","TRT01SDTM":"2019-12-31 21:28:15","AP01SDTM":"2019-12-31 21:28:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4852,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94182,"AVALU":"g/L","BASE2":2.79039,"BASE":2.83368,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15143,"PCHG2":5.42693,"CHG":0.10815,"PCHG":3.81643,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-01 21:28:15","ADY":701,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-90","SUBJID":"id-90","SITEID":"CHN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.2096,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 21:28:15","TRT01SDTM":"2019-12-31 21:28:15","AP01SDTM":"2019-12-31 21:28:15","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1312,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82233,"AVALU":"g/L","BASE2":2.79039,"BASE":2.83368,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03194,"PCHG2":1.14476,"CHG":-0.01134,"PCHG":-0.40032,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-16 21:28:15","ADY":716,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-91","SUBJID":"id-91","SITEID":"CHN-11","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.001,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-05-28","TRTSDTM":"2020-05-29 14:09:52","TRTEDTM":"2022-02-13 03:47:48","TRT01SDTM":"2020-05-29 14:09:52","TRT01EDTM":"2021-02-12 21:47:48","TRT02SDTM":"2021-02-12 21:47:48","TRT02EDTM":"2022-02-13 03:47:48","AP01SDTM":"2020-05-29 14:09:52","AP01EDTM":"2021-02-12 21:47:48","AP02SDTM":"2021-02-12 21:47:48","AP02EDTM":"2022-02-13 03:47:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":625,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":674,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7620,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.10763,"AVALU":"U/L","BASE2":14.10763,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-03 14:09:52","ADY":35,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-91","SUBJID":"id-91","SITEID":"CHN-11","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.001,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-05-28","TRTSDTM":"2020-05-29 14:09:52","TRTEDTM":"2022-02-13 03:47:48","TRT01SDTM":"2020-05-29 14:09:52","TRT01EDTM":"2021-02-12 21:47:48","TRT02SDTM":"2021-02-12 21:47:48","TRT02EDTM":"2022-02-13 03:47:48","AP01SDTM":"2020-05-29 14:09:52","AP01EDTM":"2021-02-12 21:47:48","AP02SDTM":"2021-02-12 21:47:48","AP02EDTM":"2022-02-13 03:47:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":625,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":674,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2207,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.83076,"AVALU":"U/L","BASE2":14.10763,"BASE":23.83076,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":9.72313,"PCHG2":68.92108,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-13 14:09:52","ADY":137,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-91","SUBJID":"id-91","SITEID":"CHN-11","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.001,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-05-28","TRTSDTM":"2020-05-29 14:09:52","TRTEDTM":"2022-02-13 03:47:48","TRT01SDTM":"2020-05-29 14:09:52","TRT01EDTM":"2021-02-12 21:47:48","TRT02SDTM":"2021-02-12 21:47:48","TRT02EDTM":"2022-02-13 03:47:48","AP01SDTM":"2020-05-29 14:09:52","AP01EDTM":"2021-02-12 21:47:48","AP02SDTM":"2021-02-12 21:47:48","AP02EDTM":"2022-02-13 03:47:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":625,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":674,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7983,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.2964,"AVALU":"U/L","BASE2":14.10763,"BASE":23.83076,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.18877,"PCHG2":107.66354,"CHG":5.46564,"PCHG":22.93524,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-25 14:09:52","ADY":331,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-91","SUBJID":"id-91","SITEID":"CHN-11","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.001,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-05-28","TRTSDTM":"2020-05-29 14:09:52","TRTEDTM":"2022-02-13 03:47:48","TRT01SDTM":"2020-05-29 14:09:52","TRT01EDTM":"2021-02-12 21:47:48","TRT02SDTM":"2021-02-12 21:47:48","TRT02EDTM":"2022-02-13 03:47:48","AP01SDTM":"2020-05-29 14:09:52","AP01EDTM":"2021-02-12 21:47:48","AP02SDTM":"2021-02-12 21:47:48","AP02EDTM":"2022-02-13 03:47:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":625,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":674,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3123,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.49147,"AVALU":"U/L","BASE2":14.10763,"BASE":23.83076,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.38384,"PCHG2":31.07428,"CHG":-5.33929,"PCHG":-22.40502,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-22 14:09:52","ADY":358,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-91","SUBJID":"id-91","SITEID":"CHN-11","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.001,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-05-28","TRTSDTM":"2020-05-29 14:09:52","TRTEDTM":"2022-02-13 03:47:48","TRT01SDTM":"2020-05-29 14:09:52","TRT01EDTM":"2021-02-12 21:47:48","TRT02SDTM":"2021-02-12 21:47:48","TRT02EDTM":"2022-02-13 03:47:48","AP01SDTM":"2020-05-29 14:09:52","AP01EDTM":"2021-02-12 21:47:48","AP02SDTM":"2021-02-12 21:47:48","AP02EDTM":"2022-02-13 03:47:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":625,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":674,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4557,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.15454,"AVALU":"U/L","BASE2":14.10763,"BASE":23.83076,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.04691,"PCHG2":64.1278,"CHG":-0.67622,"PCHG":-2.83759,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-27 14:09:52","ADY":577,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-91","SUBJID":"id-91","SITEID":"CHN-11","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.001,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-05-28","TRTSDTM":"2020-05-29 14:09:52","TRTEDTM":"2022-02-13 03:47:48","TRT01SDTM":"2020-05-29 14:09:52","TRT01EDTM":"2021-02-12 21:47:48","TRT02SDTM":"2021-02-12 21:47:48","TRT02EDTM":"2022-02-13 03:47:48","AP01SDTM":"2020-05-29 14:09:52","AP01EDTM":"2021-02-12 21:47:48","AP02SDTM":"2021-02-12 21:47:48","AP02EDTM":"2022-02-13 03:47:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":625,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":674,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4929,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.08664,"AVALU":"U/L","BASE2":14.10763,"BASE":23.83076,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.97901,"PCHG2":21.11631,"CHG":-6.74412,"PCHG":-28.30007,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-10 14:09:52","ADY":591,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-91","SUBJID":"id-91","SITEID":"CHN-11","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.001,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-05-28","TRTSDTM":"2020-05-29 14:09:52","TRTEDTM":"2022-02-13 03:47:48","TRT01SDTM":"2020-05-29 14:09:52","TRT01EDTM":"2021-02-12 21:47:48","TRT02SDTM":"2021-02-12 21:47:48","TRT02EDTM":"2022-02-13 03:47:48","AP01SDTM":"2020-05-29 14:09:52","AP01EDTM":"2021-02-12 21:47:48","AP02SDTM":"2021-02-12 21:47:48","AP02EDTM":"2022-02-13 03:47:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":625,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":674,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4946,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.03334,"AVALU":"U/L","BASE2":14.10763,"BASE":23.83076,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.92571,"PCHG2":98.71053,"CHG":4.20258,"PCHG":17.63513,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-27 14:09:52","ADY":608,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-91","SUBJID":"id-91","SITEID":"CHN-11","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.001,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-05-28","TRTSDTM":"2020-05-29 14:09:52","TRTEDTM":"2022-02-13 03:47:48","TRT01SDTM":"2020-05-29 14:09:52","TRT01EDTM":"2021-02-12 21:47:48","TRT02SDTM":"2021-02-12 21:47:48","TRT02EDTM":"2022-02-13 03:47:48","AP01SDTM":"2020-05-29 14:09:52","AP01EDTM":"2021-02-12 21:47:48","AP02SDTM":"2021-02-12 21:47:48","AP02EDTM":"2022-02-13 03:47:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":625,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":674,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7726,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.62864,"AVALU":"mg/L","BASE2":8.62864,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-07-03 14:09:52","ADY":35,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-91","SUBJID":"id-91","SITEID":"CHN-11","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.001,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-05-28","TRTSDTM":"2020-05-29 14:09:52","TRTEDTM":"2022-02-13 03:47:48","TRT01SDTM":"2020-05-29 14:09:52","TRT01EDTM":"2021-02-12 21:47:48","TRT02SDTM":"2021-02-12 21:47:48","TRT02EDTM":"2022-02-13 03:47:48","AP01SDTM":"2020-05-29 14:09:52","AP01EDTM":"2021-02-12 21:47:48","AP02SDTM":"2021-02-12 21:47:48","AP02EDTM":"2022-02-13 03:47:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":625,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":674,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4278,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.16202,"AVALU":"mg/L","BASE2":8.62864,"BASE":10.16202,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.53338,"PCHG2":17.77079,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-10-13 14:09:52","ADY":137,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-91","SUBJID":"id-91","SITEID":"CHN-11","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.001,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-05-28","TRTSDTM":"2020-05-29 14:09:52","TRTEDTM":"2022-02-13 03:47:48","TRT01SDTM":"2020-05-29 14:09:52","TRT01EDTM":"2021-02-12 21:47:48","TRT02SDTM":"2021-02-12 21:47:48","TRT02EDTM":"2022-02-13 03:47:48","AP01SDTM":"2020-05-29 14:09:52","AP01EDTM":"2021-02-12 21:47:48","AP02SDTM":"2021-02-12 21:47:48","AP02EDTM":"2022-02-13 03:47:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":625,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":674,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1476,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.97826,"AVALU":"mg/L","BASE2":8.62864,"BASE":10.16202,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.34962,"PCHG2":4.0518,"CHG":-1.18376,"PCHG":-11.64889,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-04-25 14:09:52","ADY":331,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-91","SUBJID":"id-91","SITEID":"CHN-11","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.001,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-05-28","TRTSDTM":"2020-05-29 14:09:52","TRTEDTM":"2022-02-13 03:47:48","TRT01SDTM":"2020-05-29 14:09:52","TRT01EDTM":"2021-02-12 21:47:48","TRT02SDTM":"2021-02-12 21:47:48","TRT02EDTM":"2022-02-13 03:47:48","AP01SDTM":"2020-05-29 14:09:52","AP01EDTM":"2021-02-12 21:47:48","AP02SDTM":"2021-02-12 21:47:48","AP02EDTM":"2022-02-13 03:47:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":625,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":674,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5116,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.03301,"AVALU":"mg/L","BASE2":8.62864,"BASE":10.16202,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.40436,"PCHG2":16.27562,"CHG":-0.12901,"PCHG":-1.26956,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"1","ADTM":"2021-05-22 14:09:52","ADY":358,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-91","SUBJID":"id-91","SITEID":"CHN-11","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.001,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-05-28","TRTSDTM":"2020-05-29 14:09:52","TRTEDTM":"2022-02-13 03:47:48","TRT01SDTM":"2020-05-29 14:09:52","TRT01EDTM":"2021-02-12 21:47:48","TRT02SDTM":"2021-02-12 21:47:48","TRT02EDTM":"2022-02-13 03:47:48","AP01SDTM":"2020-05-29 14:09:52","AP01EDTM":"2021-02-12 21:47:48","AP02SDTM":"2021-02-12 21:47:48","AP02EDTM":"2022-02-13 03:47:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":625,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":674,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4751,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.76562,"AVALU":"mg/L","BASE2":8.62864,"BASE":10.16202,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13697,"PCHG2":1.58744,"CHG":-1.3964,"PCHG":-13.7414,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-12-27 14:09:52","ADY":577,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-91","SUBJID":"id-91","SITEID":"CHN-11","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.001,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-05-28","TRTSDTM":"2020-05-29 14:09:52","TRTEDTM":"2022-02-13 03:47:48","TRT01SDTM":"2020-05-29 14:09:52","TRT01EDTM":"2021-02-12 21:47:48","TRT02SDTM":"2021-02-12 21:47:48","TRT02EDTM":"2022-02-13 03:47:48","AP01SDTM":"2020-05-29 14:09:52","AP01EDTM":"2021-02-12 21:47:48","AP02SDTM":"2021-02-12 21:47:48","AP02EDTM":"2022-02-13 03:47:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":625,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":674,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7718,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.63421,"AVALU":"mg/L","BASE2":8.62864,"BASE":10.16202,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.99443,"PCHG2":-11.52475,"CHG":-2.52781,"PCHG":-24.87505,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-3","BTOXGR":"1","ADTM":"2022-01-10 14:09:52","ADY":591,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-91","SUBJID":"id-91","SITEID":"CHN-11","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.001,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-05-28","TRTSDTM":"2020-05-29 14:09:52","TRTEDTM":"2022-02-13 03:47:48","TRT01SDTM":"2020-05-29 14:09:52","TRT01EDTM":"2021-02-12 21:47:48","TRT02SDTM":"2021-02-12 21:47:48","TRT02EDTM":"2022-02-13 03:47:48","AP01SDTM":"2020-05-29 14:09:52","AP01EDTM":"2021-02-12 21:47:48","AP02SDTM":"2021-02-12 21:47:48","AP02EDTM":"2022-02-13 03:47:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":625,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":674,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5673,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.22113,"AVALU":"mg/L","BASE2":8.62864,"BASE":10.16202,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.59249,"PCHG2":18.45587,"CHG":0.05911,"PCHG":0.58171,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"1","ADTM":"2022-01-27 14:09:52","ADY":608,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-91","SUBJID":"id-91","SITEID":"CHN-11","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.001,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-05-28","TRTSDTM":"2020-05-29 14:09:52","TRTEDTM":"2022-02-13 03:47:48","TRT01SDTM":"2020-05-29 14:09:52","TRT01EDTM":"2021-02-12 21:47:48","TRT02SDTM":"2021-02-12 21:47:48","TRT02EDTM":"2022-02-13 03:47:48","AP01SDTM":"2020-05-29 14:09:52","AP01EDTM":"2021-02-12 21:47:48","AP02SDTM":"2021-02-12 21:47:48","AP02EDTM":"2022-02-13 03:47:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":625,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":674,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3292,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9259,"AVALU":"g/L","BASE2":2.9259,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-03 14:09:52","ADY":35,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-91","SUBJID":"id-91","SITEID":"CHN-11","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.001,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-05-28","TRTSDTM":"2020-05-29 14:09:52","TRTEDTM":"2022-02-13 03:47:48","TRT01SDTM":"2020-05-29 14:09:52","TRT01EDTM":"2021-02-12 21:47:48","TRT02SDTM":"2021-02-12 21:47:48","TRT02EDTM":"2022-02-13 03:47:48","AP01SDTM":"2020-05-29 14:09:52","AP01EDTM":"2021-02-12 21:47:48","AP02SDTM":"2021-02-12 21:47:48","AP02EDTM":"2022-02-13 03:47:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":625,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":674,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8072,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90127,"AVALU":"g/L","BASE2":2.9259,"BASE":2.90127,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.02463,"PCHG2":-0.84189,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-13 14:09:52","ADY":137,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-91","SUBJID":"id-91","SITEID":"CHN-11","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.001,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-05-28","TRTSDTM":"2020-05-29 14:09:52","TRTEDTM":"2022-02-13 03:47:48","TRT01SDTM":"2020-05-29 14:09:52","TRT01EDTM":"2021-02-12 21:47:48","TRT02SDTM":"2021-02-12 21:47:48","TRT02EDTM":"2022-02-13 03:47:48","AP01SDTM":"2020-05-29 14:09:52","AP01EDTM":"2021-02-12 21:47:48","AP02SDTM":"2021-02-12 21:47:48","AP02EDTM":"2022-02-13 03:47:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":625,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":674,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7594,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96372,"AVALU":"g/L","BASE2":2.9259,"BASE":2.90127,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03781,"PCHG2":1.29242,"CHG":0.06245,"PCHG":2.15242,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-25 14:09:52","ADY":331,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-91","SUBJID":"id-91","SITEID":"CHN-11","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.001,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-05-28","TRTSDTM":"2020-05-29 14:09:52","TRTEDTM":"2022-02-13 03:47:48","TRT01SDTM":"2020-05-29 14:09:52","TRT01EDTM":"2021-02-12 21:47:48","TRT02SDTM":"2021-02-12 21:47:48","TRT02EDTM":"2022-02-13 03:47:48","AP01SDTM":"2020-05-29 14:09:52","AP01EDTM":"2021-02-12 21:47:48","AP02SDTM":"2021-02-12 21:47:48","AP02EDTM":"2022-02-13 03:47:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":625,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":674,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3618,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.73502,"AVALU":"g/L","BASE2":2.9259,"BASE":2.90127,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19088,"PCHG2":-6.52379,"CHG":-0.16625,"PCHG":-5.73015,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-22 14:09:52","ADY":358,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-91","SUBJID":"id-91","SITEID":"CHN-11","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.001,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-05-28","TRTSDTM":"2020-05-29 14:09:52","TRTEDTM":"2022-02-13 03:47:48","TRT01SDTM":"2020-05-29 14:09:52","TRT01EDTM":"2021-02-12 21:47:48","TRT02SDTM":"2021-02-12 21:47:48","TRT02EDTM":"2022-02-13 03:47:48","AP01SDTM":"2020-05-29 14:09:52","AP01EDTM":"2021-02-12 21:47:48","AP02SDTM":"2021-02-12 21:47:48","AP02EDTM":"2022-02-13 03:47:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":625,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":674,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4024,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96161,"AVALU":"g/L","BASE2":2.9259,"BASE":2.90127,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0357,"PCHG2":1.22027,"CHG":0.06034,"PCHG":2.07966,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-27 14:09:52","ADY":577,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-91","SUBJID":"id-91","SITEID":"CHN-11","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.001,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-05-28","TRTSDTM":"2020-05-29 14:09:52","TRTEDTM":"2022-02-13 03:47:48","TRT01SDTM":"2020-05-29 14:09:52","TRT01EDTM":"2021-02-12 21:47:48","TRT02SDTM":"2021-02-12 21:47:48","TRT02EDTM":"2022-02-13 03:47:48","AP01SDTM":"2020-05-29 14:09:52","AP01EDTM":"2021-02-12 21:47:48","AP02SDTM":"2021-02-12 21:47:48","AP02EDTM":"2022-02-13 03:47:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":625,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":674,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4004,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0722,"AVALU":"g/L","BASE2":2.9259,"BASE":2.90127,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1463,"PCHG2":5,"CHG":0.17093,"PCHG":5.89148,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-01-10 14:09:52","ADY":591,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-11-id-91","SUBJID":"id-91","SITEID":"CHN-11","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-11","INVNAM":"Dr. CHN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.001,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-05-28","TRTSDTM":"2020-05-29 14:09:52","TRTEDTM":"2022-02-13 03:47:48","TRT01SDTM":"2020-05-29 14:09:52","TRT01EDTM":"2021-02-12 21:47:48","TRT02SDTM":"2021-02-12 21:47:48","TRT02EDTM":"2022-02-13 03:47:48","AP01SDTM":"2020-05-29 14:09:52","AP01EDTM":"2021-02-12 21:47:48","AP02SDTM":"2021-02-12 21:47:48","AP02EDTM":"2022-02-13 03:47:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":625,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":674,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3145,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.07701,"AVALU":"g/L","BASE2":2.9259,"BASE":2.90127,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15111,"PCHG2":5.16462,"CHG":0.17574,"PCHG":6.05751,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-01-27 14:09:52","ADY":608,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-255","SUBJID":"id-255","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.49031,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-16","TRTSDTM":"2020-06-20 19:29:02","TRTEDTM":"2022-02-13 09:22:23","TRT01SDTM":"2020-06-20 19:29:02","TRT01EDTM":"2021-02-13 03:22:23","TRT02SDTM":"2021-02-13 03:22:23","TRT02EDTM":"2022-02-13 09:22:23","AP01SDTM":"2020-06-20 19:29:02","AP01EDTM":"2021-02-13 03:22:23","AP02SDTM":"2021-02-13 03:22:23","AP02EDTM":"2022-02-13 09:22:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":603,"DCSREAS":"DEATH","DTHDT":"2022-02-14","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-14","DTHADY":603,"ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7057,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.60171,"AVALU":"U/L","BASE2":8.60171,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-23 19:29:02","ADY":3,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-255","SUBJID":"id-255","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.49031,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-16","TRTSDTM":"2020-06-20 19:29:02","TRTEDTM":"2022-02-13 09:22:23","TRT01SDTM":"2020-06-20 19:29:02","TRT01EDTM":"2021-02-13 03:22:23","TRT02SDTM":"2021-02-13 03:22:23","TRT02EDTM":"2022-02-13 09:22:23","AP01SDTM":"2020-06-20 19:29:02","AP01EDTM":"2021-02-13 03:22:23","AP02SDTM":"2021-02-13 03:22:23","AP02EDTM":"2022-02-13 09:22:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":603,"DCSREAS":"DEATH","DTHDT":"2022-02-14","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-14","DTHADY":603,"ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4775,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.00918,"AVALU":"U/L","BASE2":8.60171,"BASE":7.00918,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.59253,"PCHG2":-18.5141,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-06 19:29:02","ADY":16,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-255","SUBJID":"id-255","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.49031,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-16","TRTSDTM":"2020-06-20 19:29:02","TRTEDTM":"2022-02-13 09:22:23","TRT01SDTM":"2020-06-20 19:29:02","TRT01EDTM":"2021-02-13 03:22:23","TRT02SDTM":"2021-02-13 03:22:23","TRT02EDTM":"2022-02-13 09:22:23","AP01SDTM":"2020-06-20 19:29:02","AP01EDTM":"2021-02-13 03:22:23","AP02SDTM":"2021-02-13 03:22:23","AP02EDTM":"2022-02-13 09:22:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":603,"DCSREAS":"DEATH","DTHDT":"2022-02-14","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-14","DTHADY":603,"ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4044,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.24416,"AVALU":"U/L","BASE2":8.60171,"BASE":7.00918,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.64245,"PCHG2":88.84806,"CHG":9.23498,"PCHG":131.7555,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-15 19:29:02","ADY":56,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-255","SUBJID":"id-255","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.49031,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-16","TRTSDTM":"2020-06-20 19:29:02","TRTEDTM":"2022-02-13 09:22:23","TRT01SDTM":"2020-06-20 19:29:02","TRT01EDTM":"2021-02-13 03:22:23","TRT02SDTM":"2021-02-13 03:22:23","TRT02EDTM":"2022-02-13 09:22:23","AP01SDTM":"2020-06-20 19:29:02","AP01EDTM":"2021-02-13 03:22:23","AP02SDTM":"2021-02-13 03:22:23","AP02EDTM":"2022-02-13 09:22:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":603,"DCSREAS":"DEATH","DTHDT":"2022-02-14","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-14","DTHADY":603,"ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2090,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.22768,"AVALU":"U/L","BASE2":8.60171,"BASE":7.00918,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.37403,"PCHG2":-4.34828,"CHG":1.2185,"PCHG":17.38438,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-18 19:29:02","ADY":151,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-255","SUBJID":"id-255","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.49031,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-16","TRTSDTM":"2020-06-20 19:29:02","TRTEDTM":"2022-02-13 09:22:23","TRT01SDTM":"2020-06-20 19:29:02","TRT01EDTM":"2021-02-13 03:22:23","TRT02SDTM":"2021-02-13 03:22:23","TRT02EDTM":"2022-02-13 09:22:23","AP01SDTM":"2020-06-20 19:29:02","AP01EDTM":"2021-02-13 03:22:23","AP02SDTM":"2021-02-13 03:22:23","AP02EDTM":"2022-02-13 09:22:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":603,"DCSREAS":"DEATH","DTHDT":"2022-02-14","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-14","DTHADY":603,"ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2402,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.68984,"AVALU":"U/L","BASE2":8.60171,"BASE":7.00918,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.08814,"PCHG2":70.77825,"CHG":7.68067,"PCHG":109.58012,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-22 19:29:02","ADY":581,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-255","SUBJID":"id-255","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.49031,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-16","TRTSDTM":"2020-06-20 19:29:02","TRTEDTM":"2022-02-13 09:22:23","TRT01SDTM":"2020-06-20 19:29:02","TRT01EDTM":"2021-02-13 03:22:23","TRT02SDTM":"2021-02-13 03:22:23","TRT02EDTM":"2022-02-13 09:22:23","AP01SDTM":"2020-06-20 19:29:02","AP01EDTM":"2021-02-13 03:22:23","AP02SDTM":"2021-02-13 03:22:23","AP02EDTM":"2022-02-13 09:22:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":603,"DCSREAS":"DEATH","DTHDT":"2022-02-14","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-14","DTHADY":603,"ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3248,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.60042,"AVALU":"U/L","BASE2":8.60171,"BASE":7.00918,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.99871,"PCHG2":46.48745,"CHG":5.59124,"PCHG":79.77031,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-05 19:29:02","ADY":595,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-255","SUBJID":"id-255","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.49031,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-16","TRTSDTM":"2020-06-20 19:29:02","TRTEDTM":"2022-02-13 09:22:23","TRT01SDTM":"2020-06-20 19:29:02","TRT01EDTM":"2021-02-13 03:22:23","TRT02SDTM":"2021-02-13 03:22:23","TRT02EDTM":"2022-02-13 09:22:23","AP01SDTM":"2020-06-20 19:29:02","AP01EDTM":"2021-02-13 03:22:23","AP02SDTM":"2021-02-13 03:22:23","AP02EDTM":"2022-02-13 09:22:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":603,"DCSREAS":"DEATH","DTHDT":"2022-02-14","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-14","DTHADY":603,"ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5040,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.49791,"AVALU":"U/L","BASE2":8.60171,"BASE":7.00918,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.10379,"PCHG2":-36.08344,"CHG":-1.51126,"PCHG":-21.56121,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-02-10 19:29:02","ADY":600,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-255","SUBJID":"id-255","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.49031,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-16","TRTSDTM":"2020-06-20 19:29:02","TRTEDTM":"2022-02-13 09:22:23","TRT01SDTM":"2020-06-20 19:29:02","TRT01EDTM":"2021-02-13 03:22:23","TRT02SDTM":"2021-02-13 03:22:23","TRT02EDTM":"2022-02-13 09:22:23","AP01SDTM":"2020-06-20 19:29:02","AP01EDTM":"2021-02-13 03:22:23","AP02SDTM":"2021-02-13 03:22:23","AP02EDTM":"2022-02-13 09:22:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":603,"DCSREAS":"DEATH","DTHDT":"2022-02-14","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-14","DTHADY":603,"ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4343,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.8118,"AVALU":"mg/L","BASE2":9.8118,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-23 19:29:02","ADY":3,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-255","SUBJID":"id-255","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.49031,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-16","TRTSDTM":"2020-06-20 19:29:02","TRTEDTM":"2022-02-13 09:22:23","TRT01SDTM":"2020-06-20 19:29:02","TRT01EDTM":"2021-02-13 03:22:23","TRT02SDTM":"2021-02-13 03:22:23","TRT02EDTM":"2022-02-13 09:22:23","AP01SDTM":"2020-06-20 19:29:02","AP01EDTM":"2021-02-13 03:22:23","AP02SDTM":"2021-02-13 03:22:23","AP02EDTM":"2022-02-13 09:22:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":603,"DCSREAS":"DEATH","DTHDT":"2022-02-14","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-14","DTHADY":603,"ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3116,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.6934,"AVALU":"mg/L","BASE2":9.8118,"BASE":9.6934,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.11841,"PCHG2":-1.2068,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-06 19:29:02","ADY":16,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-255","SUBJID":"id-255","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.49031,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-16","TRTSDTM":"2020-06-20 19:29:02","TRTEDTM":"2022-02-13 09:22:23","TRT01SDTM":"2020-06-20 19:29:02","TRT01EDTM":"2021-02-13 03:22:23","TRT02SDTM":"2021-02-13 03:22:23","TRT02EDTM":"2022-02-13 09:22:23","AP01SDTM":"2020-06-20 19:29:02","AP01EDTM":"2021-02-13 03:22:23","AP02SDTM":"2021-02-13 03:22:23","AP02EDTM":"2022-02-13 09:22:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":603,"DCSREAS":"DEATH","DTHDT":"2022-02-14","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-14","DTHADY":603,"ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8345,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.96023,"AVALU":"mg/L","BASE2":9.8118,"BASE":9.6934,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.85157,"PCHG2":-18.87084,"CHG":-1.73316,"PCHG":-17.87982,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-08-15 19:29:02","ADY":56,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-255","SUBJID":"id-255","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.49031,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-16","TRTSDTM":"2020-06-20 19:29:02","TRTEDTM":"2022-02-13 09:22:23","TRT01SDTM":"2020-06-20 19:29:02","TRT01EDTM":"2021-02-13 03:22:23","TRT02SDTM":"2021-02-13 03:22:23","TRT02EDTM":"2022-02-13 09:22:23","AP01SDTM":"2020-06-20 19:29:02","AP01EDTM":"2021-02-13 03:22:23","AP02SDTM":"2021-02-13 03:22:23","AP02EDTM":"2022-02-13 09:22:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":603,"DCSREAS":"DEATH","DTHDT":"2022-02-14","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-14","DTHADY":603,"ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6878,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.77066,"AVALU":"mg/L","BASE2":9.8118,"BASE":9.6934,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04114,"PCHG2":-0.41933,"CHG":0.07727,"PCHG":0.79709,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-18 19:29:02","ADY":151,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-255","SUBJID":"id-255","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.49031,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-16","TRTSDTM":"2020-06-20 19:29:02","TRTEDTM":"2022-02-13 09:22:23","TRT01SDTM":"2020-06-20 19:29:02","TRT01EDTM":"2021-02-13 03:22:23","TRT02SDTM":"2021-02-13 03:22:23","TRT02EDTM":"2022-02-13 09:22:23","AP01SDTM":"2020-06-20 19:29:02","AP01EDTM":"2021-02-13 03:22:23","AP02SDTM":"2021-02-13 03:22:23","AP02EDTM":"2022-02-13 09:22:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":603,"DCSREAS":"DEATH","DTHDT":"2022-02-14","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-14","DTHADY":603,"ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6440,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.27241,"AVALU":"mg/L","BASE2":9.8118,"BASE":9.6934,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.46061,"PCHG2":4.69442,"CHG":0.57902,"PCHG":5.97331,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-01-22 19:29:02","ADY":581,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-255","SUBJID":"id-255","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.49031,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-16","TRTSDTM":"2020-06-20 19:29:02","TRTEDTM":"2022-02-13 09:22:23","TRT01SDTM":"2020-06-20 19:29:02","TRT01EDTM":"2021-02-13 03:22:23","TRT02SDTM":"2021-02-13 03:22:23","TRT02EDTM":"2022-02-13 09:22:23","AP01SDTM":"2020-06-20 19:29:02","AP01EDTM":"2021-02-13 03:22:23","AP02SDTM":"2021-02-13 03:22:23","AP02EDTM":"2022-02-13 09:22:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":603,"DCSREAS":"DEATH","DTHDT":"2022-02-14","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-14","DTHADY":603,"ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1080,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.2669,"AVALU":"mg/L","BASE2":9.8118,"BASE":9.6934,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.5449,"PCHG2":-15.74532,"CHG":-1.42649,"PCHG":-14.71611,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-05 19:29:02","ADY":595,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-255","SUBJID":"id-255","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.49031,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-16","TRTSDTM":"2020-06-20 19:29:02","TRTEDTM":"2022-02-13 09:22:23","TRT01SDTM":"2020-06-20 19:29:02","TRT01EDTM":"2021-02-13 03:22:23","TRT02SDTM":"2021-02-13 03:22:23","TRT02EDTM":"2022-02-13 09:22:23","AP01SDTM":"2020-06-20 19:29:02","AP01EDTM":"2021-02-13 03:22:23","AP02SDTM":"2021-02-13 03:22:23","AP02EDTM":"2022-02-13 09:22:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":603,"DCSREAS":"DEATH","DTHDT":"2022-02-14","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-14","DTHADY":603,"ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4434,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.73555,"AVALU":"mg/L","BASE2":9.8118,"BASE":9.6934,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07625,"PCHG2":-0.77714,"CHG":0.04216,"PCHG":0.43491,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-10 19:29:02","ADY":600,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-255","SUBJID":"id-255","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.49031,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-16","TRTSDTM":"2020-06-20 19:29:02","TRTEDTM":"2022-02-13 09:22:23","TRT01SDTM":"2020-06-20 19:29:02","TRT01EDTM":"2021-02-13 03:22:23","TRT02SDTM":"2021-02-13 03:22:23","TRT02EDTM":"2022-02-13 09:22:23","AP01SDTM":"2020-06-20 19:29:02","AP01EDTM":"2021-02-13 03:22:23","AP02SDTM":"2021-02-13 03:22:23","AP02EDTM":"2022-02-13 09:22:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":603,"DCSREAS":"DEATH","DTHDT":"2022-02-14","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-14","DTHADY":603,"ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7079,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89837,"AVALU":"g/L","BASE2":2.89837,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-23 19:29:02","ADY":3,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-255","SUBJID":"id-255","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.49031,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-16","TRTSDTM":"2020-06-20 19:29:02","TRTEDTM":"2022-02-13 09:22:23","TRT01SDTM":"2020-06-20 19:29:02","TRT01EDTM":"2021-02-13 03:22:23","TRT02SDTM":"2021-02-13 03:22:23","TRT02EDTM":"2022-02-13 09:22:23","AP01SDTM":"2020-06-20 19:29:02","AP01EDTM":"2021-02-13 03:22:23","AP02SDTM":"2021-02-13 03:22:23","AP02EDTM":"2022-02-13 09:22:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":603,"DCSREAS":"DEATH","DTHDT":"2022-02-14","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-14","DTHADY":603,"ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7331,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.72665,"AVALU":"g/L","BASE2":2.89837,"BASE":2.72665,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.17172,"PCHG2":-5.92486,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-06 19:29:02","ADY":16,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-255","SUBJID":"id-255","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.49031,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-16","TRTSDTM":"2020-06-20 19:29:02","TRTEDTM":"2022-02-13 09:22:23","TRT01SDTM":"2020-06-20 19:29:02","TRT01EDTM":"2021-02-13 03:22:23","TRT02SDTM":"2021-02-13 03:22:23","TRT02EDTM":"2022-02-13 09:22:23","AP01SDTM":"2020-06-20 19:29:02","AP01EDTM":"2021-02-13 03:22:23","AP02SDTM":"2021-02-13 03:22:23","AP02EDTM":"2022-02-13 09:22:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":603,"DCSREAS":"DEATH","DTHDT":"2022-02-14","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-14","DTHADY":603,"ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7108,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83108,"AVALU":"g/L","BASE2":2.89837,"BASE":2.72665,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06729,"PCHG2":-2.32164,"CHG":0.10443,"PCHG":3.83015,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-15 19:29:02","ADY":56,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-255","SUBJID":"id-255","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.49031,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-16","TRTSDTM":"2020-06-20 19:29:02","TRTEDTM":"2022-02-13 09:22:23","TRT01SDTM":"2020-06-20 19:29:02","TRT01EDTM":"2021-02-13 03:22:23","TRT02SDTM":"2021-02-13 03:22:23","TRT02EDTM":"2022-02-13 09:22:23","AP01SDTM":"2020-06-20 19:29:02","AP01EDTM":"2021-02-13 03:22:23","AP02SDTM":"2021-02-13 03:22:23","AP02EDTM":"2022-02-13 09:22:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":603,"DCSREAS":"DEATH","DTHDT":"2022-02-14","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-14","DTHADY":603,"ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7156,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90283,"AVALU":"g/L","BASE2":2.89837,"BASE":2.72665,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00446,"PCHG2":0.1539,"CHG":0.17619,"PCHG":6.46161,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-18 19:29:02","ADY":151,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-255","SUBJID":"id-255","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.49031,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-16","TRTSDTM":"2020-06-20 19:29:02","TRTEDTM":"2022-02-13 09:22:23","TRT01SDTM":"2020-06-20 19:29:02","TRT01EDTM":"2021-02-13 03:22:23","TRT02SDTM":"2021-02-13 03:22:23","TRT02EDTM":"2022-02-13 09:22:23","AP01SDTM":"2020-06-20 19:29:02","AP01EDTM":"2021-02-13 03:22:23","AP02SDTM":"2021-02-13 03:22:23","AP02EDTM":"2022-02-13 09:22:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":603,"DCSREAS":"DEATH","DTHDT":"2022-02-14","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-14","DTHADY":603,"ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5813,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92184,"AVALU":"g/L","BASE2":2.89837,"BASE":2.72665,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02347,"PCHG2":0.80981,"CHG":0.1952,"PCHG":7.15882,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-22 19:29:02","ADY":581,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-255","SUBJID":"id-255","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.49031,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-16","TRTSDTM":"2020-06-20 19:29:02","TRTEDTM":"2022-02-13 09:22:23","TRT01SDTM":"2020-06-20 19:29:02","TRT01EDTM":"2021-02-13 03:22:23","TRT02SDTM":"2021-02-13 03:22:23","TRT02EDTM":"2022-02-13 09:22:23","AP01SDTM":"2020-06-20 19:29:02","AP01EDTM":"2021-02-13 03:22:23","AP02SDTM":"2021-02-13 03:22:23","AP02EDTM":"2022-02-13 09:22:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":603,"DCSREAS":"DEATH","DTHDT":"2022-02-14","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-14","DTHADY":603,"ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":335,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.09394,"AVALU":"g/L","BASE2":2.89837,"BASE":2.72665,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.19557,"PCHG2":6.74742,"CHG":0.36729,"PCHG":13.47039,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-02-05 19:29:02","ADY":595,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-255","SUBJID":"id-255","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.49031,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-16","TRTSDTM":"2020-06-20 19:29:02","TRTEDTM":"2022-02-13 09:22:23","TRT01SDTM":"2020-06-20 19:29:02","TRT01EDTM":"2021-02-13 03:22:23","TRT02SDTM":"2021-02-13 03:22:23","TRT02EDTM":"2022-02-13 09:22:23","AP01SDTM":"2020-06-20 19:29:02","AP01EDTM":"2021-02-13 03:22:23","AP02SDTM":"2021-02-13 03:22:23","AP02EDTM":"2022-02-13 09:22:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":603,"DCSREAS":"DEATH","DTHDT":"2022-02-14","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-14","DTHADY":603,"ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4603,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79922,"AVALU":"g/L","BASE2":2.89837,"BASE":2.72665,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09915,"PCHG2":-3.42077,"CHG":0.07258,"PCHG":2.6618,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-10 19:29:02","ADY":600,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-258","SUBJID":"id-258","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.71573,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-01","TRTSDTM":"2020-03-01 06:38:54","TRTEDTM":"2022-02-19 17:46:08","TRT01SDTM":"2020-03-01 06:38:54","TRT01EDTM":"2021-02-19 11:46:08","TRT02SDTM":"2021-02-19 11:46:08","TRT02EDTM":"2022-02-19 17:46:08","AP01SDTM":"2020-03-01 06:38:54","AP01EDTM":"2021-02-19 11:46:08","AP02SDTM":"2021-02-19 11:46:08","AP02EDTM":"2022-02-19 17:46:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":721,"DCSREAS":"DEATH","DTHDT":"2022-03-28","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":37,"LDDTHGR1":">30","LSTALVDT":"2022-03-28","DTHADY":756,"ADTHAUT":"No","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1443,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.866,"AVALU":"U/L","BASE2":17.866,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-3","ADTM":"2020-03-14 06:38:54","ADY":13,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-258","SUBJID":"id-258","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.71573,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-01","TRTSDTM":"2020-03-01 06:38:54","TRTEDTM":"2022-02-19 17:46:08","TRT01SDTM":"2020-03-01 06:38:54","TRT01EDTM":"2021-02-19 11:46:08","TRT02SDTM":"2021-02-19 11:46:08","TRT02EDTM":"2022-02-19 17:46:08","AP01SDTM":"2020-03-01 06:38:54","AP01EDTM":"2021-02-19 11:46:08","AP02SDTM":"2021-02-19 11:46:08","AP02EDTM":"2022-02-19 17:46:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":721,"DCSREAS":"DEATH","DTHDT":"2022-03-28","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":37,"LDDTHGR1":">30","LSTALVDT":"2022-03-28","DTHADY":756,"ADTHAUT":"No","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3237,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.54638,"AVALU":"U/L","BASE2":17.866,"BASE":0.54638,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-17.31962,"PCHG2":-96.94179,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2020-06-11 06:38:54","ADY":102,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-258","SUBJID":"id-258","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.71573,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-01","TRTSDTM":"2020-03-01 06:38:54","TRTEDTM":"2022-02-19 17:46:08","TRT01SDTM":"2020-03-01 06:38:54","TRT01EDTM":"2021-02-19 11:46:08","TRT02SDTM":"2021-02-19 11:46:08","TRT02EDTM":"2022-02-19 17:46:08","AP01SDTM":"2020-03-01 06:38:54","AP01EDTM":"2021-02-19 11:46:08","AP02SDTM":"2021-02-19 11:46:08","AP02EDTM":"2022-02-19 17:46:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":721,"DCSREAS":"DEATH","DTHDT":"2022-03-28","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":37,"LDDTHGR1":">30","LSTALVDT":"2022-03-28","DTHADY":756,"ADTHAUT":"No","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3014,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.54156,"AVALU":"U/L","BASE2":17.866,"BASE":0.54638,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.32444,"PCHG2":-96.96875,"CHG":-0.00482,"PCHG":-0.88165,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-2","BTOXGR":"-3","ADTM":"2020-11-06 06:38:54","ADY":250,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-258","SUBJID":"id-258","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.71573,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-01","TRTSDTM":"2020-03-01 06:38:54","TRTEDTM":"2022-02-19 17:46:08","TRT01SDTM":"2020-03-01 06:38:54","TRT01EDTM":"2021-02-19 11:46:08","TRT02SDTM":"2021-02-19 11:46:08","TRT02EDTM":"2022-02-19 17:46:08","AP01SDTM":"2020-03-01 06:38:54","AP01EDTM":"2021-02-19 11:46:08","AP02SDTM":"2021-02-19 11:46:08","AP02EDTM":"2022-02-19 17:46:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":721,"DCSREAS":"DEATH","DTHDT":"2022-03-28","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":37,"LDDTHGR1":">30","LSTALVDT":"2022-03-28","DTHADY":756,"ADTHAUT":"No","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6730,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.33248,"AVALU":"U/L","BASE2":17.866,"BASE":0.54638,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.53352,"PCHG2":-47.76402,"CHG":8.7861,"PCHG":1608.05648,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2020-11-19 06:38:54","ADY":263,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-258","SUBJID":"id-258","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.71573,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-01","TRTSDTM":"2020-03-01 06:38:54","TRTEDTM":"2022-02-19 17:46:08","TRT01SDTM":"2020-03-01 06:38:54","TRT01EDTM":"2021-02-19 11:46:08","TRT02SDTM":"2021-02-19 11:46:08","TRT02EDTM":"2022-02-19 17:46:08","AP01SDTM":"2020-03-01 06:38:54","AP01EDTM":"2021-02-19 11:46:08","AP02SDTM":"2021-02-19 11:46:08","AP02EDTM":"2022-02-19 17:46:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":721,"DCSREAS":"DEATH","DTHDT":"2022-03-28","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":37,"LDDTHGR1":">30","LSTALVDT":"2022-03-28","DTHADY":756,"ADTHAUT":"No","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":510,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.98864,"AVALU":"U/L","BASE2":17.866,"BASE":0.54638,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.12264,"PCHG2":17.47811,"CHG":20.44226,"PCHG":3741.39899,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-03-13 06:38:54","ADY":377,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-258","SUBJID":"id-258","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.71573,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-01","TRTSDTM":"2020-03-01 06:38:54","TRTEDTM":"2022-02-19 17:46:08","TRT01SDTM":"2020-03-01 06:38:54","TRT01EDTM":"2021-02-19 11:46:08","TRT02SDTM":"2021-02-19 11:46:08","TRT02EDTM":"2022-02-19 17:46:08","AP01SDTM":"2020-03-01 06:38:54","AP01EDTM":"2021-02-19 11:46:08","AP02SDTM":"2021-02-19 11:46:08","AP02EDTM":"2022-02-19 17:46:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":721,"DCSREAS":"DEATH","DTHDT":"2022-03-28","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":37,"LDDTHGR1":">30","LSTALVDT":"2022-03-28","DTHADY":756,"ADTHAUT":"No","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5228,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.15684,"AVALU":"U/L","BASE2":17.866,"BASE":0.54638,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.29084,"PCHG2":40.80844,"CHG":24.61046,"PCHG":4504.27396,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-05-03 06:38:54","ADY":428,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-258","SUBJID":"id-258","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.71573,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-01","TRTSDTM":"2020-03-01 06:38:54","TRTEDTM":"2022-02-19 17:46:08","TRT01SDTM":"2020-03-01 06:38:54","TRT01EDTM":"2021-02-19 11:46:08","TRT02SDTM":"2021-02-19 11:46:08","TRT02EDTM":"2022-02-19 17:46:08","AP01SDTM":"2020-03-01 06:38:54","AP01EDTM":"2021-02-19 11:46:08","AP02SDTM":"2021-02-19 11:46:08","AP02EDTM":"2022-02-19 17:46:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":721,"DCSREAS":"DEATH","DTHDT":"2022-03-28","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":37,"LDDTHGR1":">30","LSTALVDT":"2022-03-28","DTHADY":756,"ADTHAUT":"No","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1363,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.74842,"AVALU":"U/L","BASE2":17.866,"BASE":0.54638,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.88241,"PCHG2":21.73072,"CHG":21.20204,"PCHG":3880.45458,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-12-18 06:38:54","ADY":657,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-258","SUBJID":"id-258","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.71573,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-01","TRTSDTM":"2020-03-01 06:38:54","TRTEDTM":"2022-02-19 17:46:08","TRT01SDTM":"2020-03-01 06:38:54","TRT01EDTM":"2021-02-19 11:46:08","TRT02SDTM":"2021-02-19 11:46:08","TRT02EDTM":"2022-02-19 17:46:08","AP01SDTM":"2020-03-01 06:38:54","AP01EDTM":"2021-02-19 11:46:08","AP02SDTM":"2021-02-19 11:46:08","AP02EDTM":"2022-02-19 17:46:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":721,"DCSREAS":"DEATH","DTHDT":"2022-03-28","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":37,"LDDTHGR1":">30","LSTALVDT":"2022-03-28","DTHADY":756,"ADTHAUT":"No","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7224,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.41497,"AVALU":"mg/L","BASE2":7.41497,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-03-14 06:38:54","ADY":13,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-258","SUBJID":"id-258","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.71573,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-01","TRTSDTM":"2020-03-01 06:38:54","TRTEDTM":"2022-02-19 17:46:08","TRT01SDTM":"2020-03-01 06:38:54","TRT01EDTM":"2021-02-19 11:46:08","TRT02SDTM":"2021-02-19 11:46:08","TRT02EDTM":"2022-02-19 17:46:08","AP01SDTM":"2020-03-01 06:38:54","AP01EDTM":"2021-02-19 11:46:08","AP02SDTM":"2021-02-19 11:46:08","AP02EDTM":"2022-02-19 17:46:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":721,"DCSREAS":"DEATH","DTHDT":"2022-03-28","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":37,"LDDTHGR1":">30","LSTALVDT":"2022-03-28","DTHADY":756,"ADTHAUT":"No","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6327,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.35856,"AVALU":"mg/L","BASE2":7.41497,"BASE":8.35856,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.9436,"PCHG2":12.72559,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-11 06:38:54","ADY":102,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-258","SUBJID":"id-258","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.71573,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-01","TRTSDTM":"2020-03-01 06:38:54","TRTEDTM":"2022-02-19 17:46:08","TRT01SDTM":"2020-03-01 06:38:54","TRT01EDTM":"2021-02-19 11:46:08","TRT02SDTM":"2021-02-19 11:46:08","TRT02EDTM":"2022-02-19 17:46:08","AP01SDTM":"2020-03-01 06:38:54","AP01EDTM":"2021-02-19 11:46:08","AP02SDTM":"2021-02-19 11:46:08","AP02EDTM":"2022-02-19 17:46:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":721,"DCSREAS":"DEATH","DTHDT":"2022-03-28","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":37,"LDDTHGR1":">30","LSTALVDT":"2022-03-28","DTHADY":756,"ADTHAUT":"No","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4903,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.14633,"AVALU":"mg/L","BASE2":7.41497,"BASE":8.35856,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.73136,"PCHG2":23.3496,"CHG":0.78777,"PCHG":9.42466,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-06 06:38:54","ADY":250,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-258","SUBJID":"id-258","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.71573,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-01","TRTSDTM":"2020-03-01 06:38:54","TRTEDTM":"2022-02-19 17:46:08","TRT01SDTM":"2020-03-01 06:38:54","TRT01EDTM":"2021-02-19 11:46:08","TRT02SDTM":"2021-02-19 11:46:08","TRT02EDTM":"2022-02-19 17:46:08","AP01SDTM":"2020-03-01 06:38:54","AP01EDTM":"2021-02-19 11:46:08","AP02SDTM":"2021-02-19 11:46:08","AP02EDTM":"2022-02-19 17:46:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":721,"DCSREAS":"DEATH","DTHDT":"2022-03-28","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":37,"LDDTHGR1":">30","LSTALVDT":"2022-03-28","DTHADY":756,"ADTHAUT":"No","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5025,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.69984,"AVALU":"mg/L","BASE2":7.41497,"BASE":8.35856,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.28487,"PCHG2":17.32809,"CHG":0.34127,"PCHG":4.08292,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-19 06:38:54","ADY":263,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-258","SUBJID":"id-258","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.71573,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-01","TRTSDTM":"2020-03-01 06:38:54","TRTEDTM":"2022-02-19 17:46:08","TRT01SDTM":"2020-03-01 06:38:54","TRT01EDTM":"2021-02-19 11:46:08","TRT02SDTM":"2021-02-19 11:46:08","TRT02EDTM":"2022-02-19 17:46:08","AP01SDTM":"2020-03-01 06:38:54","AP01EDTM":"2021-02-19 11:46:08","AP02SDTM":"2021-02-19 11:46:08","AP02EDTM":"2022-02-19 17:46:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":721,"DCSREAS":"DEATH","DTHDT":"2022-03-28","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":37,"LDDTHGR1":">30","LSTALVDT":"2022-03-28","DTHADY":756,"ADTHAUT":"No","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7163,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.33683,"AVALU":"mg/L","BASE2":7.41497,"BASE":8.35856,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.92186,"PCHG2":25.91867,"CHG":0.97826,"PCHG":11.70371,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-13 06:38:54","ADY":377,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-258","SUBJID":"id-258","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.71573,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-01","TRTSDTM":"2020-03-01 06:38:54","TRTEDTM":"2022-02-19 17:46:08","TRT01SDTM":"2020-03-01 06:38:54","TRT01EDTM":"2021-02-19 11:46:08","TRT02SDTM":"2021-02-19 11:46:08","TRT02EDTM":"2022-02-19 17:46:08","AP01SDTM":"2020-03-01 06:38:54","AP01EDTM":"2021-02-19 11:46:08","AP02SDTM":"2021-02-19 11:46:08","AP02EDTM":"2022-02-19 17:46:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":721,"DCSREAS":"DEATH","DTHDT":"2022-03-28","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":37,"LDDTHGR1":">30","LSTALVDT":"2022-03-28","DTHADY":756,"ADTHAUT":"No","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6116,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.41892,"AVALU":"mg/L","BASE2":7.41497,"BASE":8.35856,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.00396,"PCHG2":27.02586,"CHG":1.06036,"PCHG":12.68591,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-03 06:38:54","ADY":428,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-258","SUBJID":"id-258","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.71573,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-01","TRTSDTM":"2020-03-01 06:38:54","TRTEDTM":"2022-02-19 17:46:08","TRT01SDTM":"2020-03-01 06:38:54","TRT01EDTM":"2021-02-19 11:46:08","TRT02SDTM":"2021-02-19 11:46:08","TRT02EDTM":"2022-02-19 17:46:08","AP01SDTM":"2020-03-01 06:38:54","AP01EDTM":"2021-02-19 11:46:08","AP02SDTM":"2021-02-19 11:46:08","AP02EDTM":"2022-02-19 17:46:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":721,"DCSREAS":"DEATH","DTHDT":"2022-03-28","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":37,"LDDTHGR1":">30","LSTALVDT":"2022-03-28","DTHADY":756,"ADTHAUT":"No","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1979,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.04426,"AVALU":"mg/L","BASE2":7.41497,"BASE":8.35856,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.6293,"PCHG2":48.94559,"CHG":2.6857,"PCHG":32.13112,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-12-18 06:38:54","ADY":657,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-258","SUBJID":"id-258","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.71573,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-01","TRTSDTM":"2020-03-01 06:38:54","TRTEDTM":"2022-02-19 17:46:08","TRT01SDTM":"2020-03-01 06:38:54","TRT01EDTM":"2021-02-19 11:46:08","TRT02SDTM":"2021-02-19 11:46:08","TRT02EDTM":"2022-02-19 17:46:08","AP01SDTM":"2020-03-01 06:38:54","AP01EDTM":"2021-02-19 11:46:08","AP02SDTM":"2021-02-19 11:46:08","AP02EDTM":"2022-02-19 17:46:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":721,"DCSREAS":"DEATH","DTHDT":"2022-03-28","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":37,"LDDTHGR1":">30","LSTALVDT":"2022-03-28","DTHADY":756,"ADTHAUT":"No","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2848,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95143,"AVALU":"g/L","BASE2":2.95143,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-14 06:38:54","ADY":13,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-258","SUBJID":"id-258","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.71573,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-01","TRTSDTM":"2020-03-01 06:38:54","TRTEDTM":"2022-02-19 17:46:08","TRT01SDTM":"2020-03-01 06:38:54","TRT01EDTM":"2021-02-19 11:46:08","TRT02SDTM":"2021-02-19 11:46:08","TRT02EDTM":"2022-02-19 17:46:08","AP01SDTM":"2020-03-01 06:38:54","AP01EDTM":"2021-02-19 11:46:08","AP02SDTM":"2021-02-19 11:46:08","AP02EDTM":"2022-02-19 17:46:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":721,"DCSREAS":"DEATH","DTHDT":"2022-03-28","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":37,"LDDTHGR1":">30","LSTALVDT":"2022-03-28","DTHADY":756,"ADTHAUT":"No","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":401,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81857,"AVALU":"g/L","BASE2":2.95143,"BASE":2.81857,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.13286,"PCHG2":-4.50154,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-11 06:38:54","ADY":102,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-258","SUBJID":"id-258","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.71573,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-01","TRTSDTM":"2020-03-01 06:38:54","TRTEDTM":"2022-02-19 17:46:08","TRT01SDTM":"2020-03-01 06:38:54","TRT01EDTM":"2021-02-19 11:46:08","TRT02SDTM":"2021-02-19 11:46:08","TRT02EDTM":"2022-02-19 17:46:08","AP01SDTM":"2020-03-01 06:38:54","AP01EDTM":"2021-02-19 11:46:08","AP02SDTM":"2021-02-19 11:46:08","AP02EDTM":"2022-02-19 17:46:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":721,"DCSREAS":"DEATH","DTHDT":"2022-03-28","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":37,"LDDTHGR1":">30","LSTALVDT":"2022-03-28","DTHADY":756,"ADTHAUT":"No","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7388,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94165,"AVALU":"g/L","BASE2":2.95143,"BASE":2.81857,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00978,"PCHG2":-0.33127,"CHG":0.12308,"PCHG":4.36685,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-06 06:38:54","ADY":250,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-258","SUBJID":"id-258","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.71573,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-01","TRTSDTM":"2020-03-01 06:38:54","TRTEDTM":"2022-02-19 17:46:08","TRT01SDTM":"2020-03-01 06:38:54","TRT01EDTM":"2021-02-19 11:46:08","TRT02SDTM":"2021-02-19 11:46:08","TRT02EDTM":"2022-02-19 17:46:08","AP01SDTM":"2020-03-01 06:38:54","AP01EDTM":"2021-02-19 11:46:08","AP02SDTM":"2021-02-19 11:46:08","AP02EDTM":"2022-02-19 17:46:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":721,"DCSREAS":"DEATH","DTHDT":"2022-03-28","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":37,"LDDTHGR1":">30","LSTALVDT":"2022-03-28","DTHADY":756,"ADTHAUT":"No","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5541,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.06503,"AVALU":"g/L","BASE2":2.95143,"BASE":2.81857,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1136,"PCHG2":3.8491,"CHG":0.24646,"PCHG":8.74427,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-11-19 06:38:54","ADY":263,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-258","SUBJID":"id-258","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.71573,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-01","TRTSDTM":"2020-03-01 06:38:54","TRTEDTM":"2022-02-19 17:46:08","TRT01SDTM":"2020-03-01 06:38:54","TRT01EDTM":"2021-02-19 11:46:08","TRT02SDTM":"2021-02-19 11:46:08","TRT02EDTM":"2022-02-19 17:46:08","AP01SDTM":"2020-03-01 06:38:54","AP01EDTM":"2021-02-19 11:46:08","AP02SDTM":"2021-02-19 11:46:08","AP02EDTM":"2022-02-19 17:46:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":721,"DCSREAS":"DEATH","DTHDT":"2022-03-28","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":37,"LDDTHGR1":">30","LSTALVDT":"2022-03-28","DTHADY":756,"ADTHAUT":"No","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":903,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81406,"AVALU":"g/L","BASE2":2.95143,"BASE":2.81857,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13737,"PCHG2":-4.65443,"CHG":-0.00451,"PCHG":-0.1601,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-13 06:38:54","ADY":377,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-258","SUBJID":"id-258","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.71573,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-01","TRTSDTM":"2020-03-01 06:38:54","TRTEDTM":"2022-02-19 17:46:08","TRT01SDTM":"2020-03-01 06:38:54","TRT01EDTM":"2021-02-19 11:46:08","TRT02SDTM":"2021-02-19 11:46:08","TRT02EDTM":"2022-02-19 17:46:08","AP01SDTM":"2020-03-01 06:38:54","AP01EDTM":"2021-02-19 11:46:08","AP02SDTM":"2021-02-19 11:46:08","AP02EDTM":"2022-02-19 17:46:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":721,"DCSREAS":"DEATH","DTHDT":"2022-03-28","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":37,"LDDTHGR1":">30","LSTALVDT":"2022-03-28","DTHADY":756,"ADTHAUT":"No","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1394,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95728,"AVALU":"g/L","BASE2":2.95143,"BASE":2.81857,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00585,"PCHG2":0.19804,"CHG":0.1387,"PCHG":4.92111,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-03 06:38:54","ADY":428,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-258","SUBJID":"id-258","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":1.71573,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-01","TRTSDTM":"2020-03-01 06:38:54","TRTEDTM":"2022-02-19 17:46:08","TRT01SDTM":"2020-03-01 06:38:54","TRT01EDTM":"2021-02-19 11:46:08","TRT02SDTM":"2021-02-19 11:46:08","TRT02EDTM":"2022-02-19 17:46:08","AP01SDTM":"2020-03-01 06:38:54","AP01EDTM":"2021-02-19 11:46:08","AP02SDTM":"2021-02-19 11:46:08","AP02EDTM":"2022-02-19 17:46:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":721,"DCSREAS":"DEATH","DTHDT":"2022-03-28","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":37,"LDDTHGR1":">30","LSTALVDT":"2022-03-28","DTHADY":756,"ADTHAUT":"No","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5235,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90582,"AVALU":"g/L","BASE2":2.95143,"BASE":2.81857,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04561,"PCHG2":-1.54537,"CHG":0.08725,"PCHG":3.09552,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-18 06:38:54","ADY":657,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-266","SUBJID":"id-266","SITEID":"CHN-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.29142,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-27","TRTSDTM":"2019-10-29 08:14:32","TRT01SDTM":"2019-10-29 08:14:32","AP01SDTM":"2019-10-29 08:14:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4742,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.7573,"AVALU":"U/L","BASE2":14.7573,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-10 08:14:32","ADY":42,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-266","SUBJID":"id-266","SITEID":"CHN-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.29142,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-27","TRTSDTM":"2019-10-29 08:14:32","TRT01SDTM":"2019-10-29 08:14:32","AP01SDTM":"2019-10-29 08:14:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5115,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.4599,"AVALU":"U/L","BASE2":14.7573,"BASE":9.4599,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-5.2974,"PCHG2":-35.8968,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-03 08:14:32","ADY":126,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-266","SUBJID":"id-266","SITEID":"CHN-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.29142,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-27","TRTSDTM":"2019-10-29 08:14:32","TRT01SDTM":"2019-10-29 08:14:32","AP01SDTM":"2019-10-29 08:14:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1956,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.55293,"AVALU":"U/L","BASE2":14.7573,"BASE":9.4599,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.79563,"PCHG2":59.60192,"CHG":14.09303,"PCHG":148.97652,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-04 08:14:32","ADY":158,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-266","SUBJID":"id-266","SITEID":"CHN-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.29142,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-27","TRTSDTM":"2019-10-29 08:14:32","TRT01SDTM":"2019-10-29 08:14:32","AP01SDTM":"2019-10-29 08:14:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3559,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.60637,"AVALU":"U/L","BASE2":14.7573,"BASE":9.4599,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.84908,"PCHG2":80.293,"CHG":17.14647,"PCHG":181.25429,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-07 08:14:32","ADY":161,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-266","SUBJID":"id-266","SITEID":"CHN-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.29142,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-27","TRTSDTM":"2019-10-29 08:14:32","TRT01SDTM":"2019-10-29 08:14:32","AP01SDTM":"2019-10-29 08:14:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":236,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.69006,"AVALU":"U/L","BASE2":14.7573,"BASE":9.4599,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06724,"PCHG2":-0.45563,"CHG":5.23016,"PCHG":55.28768,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-04 08:14:32","ADY":372,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-266","SUBJID":"id-266","SITEID":"CHN-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.29142,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-27","TRTSDTM":"2019-10-29 08:14:32","TRT01SDTM":"2019-10-29 08:14:32","AP01SDTM":"2019-10-29 08:14:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6104,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":35.09923,"AVALU":"U/L","BASE2":14.7573,"BASE":9.4599,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":20.34193,"PCHG2":137.8432,"CHG":25.63933,"PCHG":271.0317,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-22 08:14:32","ADY":451,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-266","SUBJID":"id-266","SITEID":"CHN-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.29142,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-27","TRTSDTM":"2019-10-29 08:14:32","TRT01SDTM":"2019-10-29 08:14:32","AP01SDTM":"2019-10-29 08:14:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5352,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":38.34002,"AVALU":"U/L","BASE2":14.7573,"BASE":9.4599,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":23.58273,"PCHG2":159.80383,"CHG":28.88012,"PCHG":305.28995,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-17 08:14:32","ADY":566,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-266","SUBJID":"id-266","SITEID":"CHN-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.29142,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-27","TRTSDTM":"2019-10-29 08:14:32","TRT01SDTM":"2019-10-29 08:14:32","AP01SDTM":"2019-10-29 08:14:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":754,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.94981,"AVALU":"mg/L","BASE2":9.94981,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-10 08:14:32","ADY":42,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-266","SUBJID":"id-266","SITEID":"CHN-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.29142,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-27","TRTSDTM":"2019-10-29 08:14:32","TRT01SDTM":"2019-10-29 08:14:32","AP01SDTM":"2019-10-29 08:14:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4276,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.72254,"AVALU":"mg/L","BASE2":9.94981,"BASE":8.72254,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.22727,"PCHG2":-12.33463,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-03 08:14:32","ADY":126,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-266","SUBJID":"id-266","SITEID":"CHN-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.29142,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-27","TRTSDTM":"2019-10-29 08:14:32","TRT01SDTM":"2019-10-29 08:14:32","AP01SDTM":"2019-10-29 08:14:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":727,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.49987,"AVALU":"mg/L","BASE2":9.94981,"BASE":8.72254,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.44995,"PCHG2":-14.5726,"CHG":-0.22267,"PCHG":-2.55285,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-04 08:14:32","ADY":158,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-266","SUBJID":"id-266","SITEID":"CHN-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.29142,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-27","TRTSDTM":"2019-10-29 08:14:32","TRT01SDTM":"2019-10-29 08:14:32","AP01SDTM":"2019-10-29 08:14:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7571,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.66584,"AVALU":"mg/L","BASE2":9.94981,"BASE":8.72254,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.28397,"PCHG2":-12.90449,"CHG":-0.0567,"PCHG":-0.65004,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-07 08:14:32","ADY":161,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-266","SUBJID":"id-266","SITEID":"CHN-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.29142,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-27","TRTSDTM":"2019-10-29 08:14:32","TRT01SDTM":"2019-10-29 08:14:32","AP01SDTM":"2019-10-29 08:14:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3949,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.47509,"AVALU":"mg/L","BASE2":9.94981,"BASE":8.72254,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.47473,"PCHG2":-24.87209,"CHG":-1.24745,"PCHG":-14.30149,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-11-04 08:14:32","ADY":372,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-266","SUBJID":"id-266","SITEID":"CHN-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.29142,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-27","TRTSDTM":"2019-10-29 08:14:32","TRT01SDTM":"2019-10-29 08:14:32","AP01SDTM":"2019-10-29 08:14:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4749,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.93959,"AVALU":"mg/L","BASE2":9.94981,"BASE":8.72254,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01023,"PCHG2":-0.1028,"CHG":1.21704,"PCHG":13.95287,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-22 08:14:32","ADY":451,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-266","SUBJID":"id-266","SITEID":"CHN-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.29142,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-27","TRTSDTM":"2019-10-29 08:14:32","TRT01SDTM":"2019-10-29 08:14:32","AP01SDTM":"2019-10-29 08:14:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7804,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.3583,"AVALU":"mg/L","BASE2":9.94981,"BASE":8.72254,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.59151,"PCHG2":-26.04586,"CHG":-1.36424,"PCHG":-15.64041,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-05-17 08:14:32","ADY":566,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-266","SUBJID":"id-266","SITEID":"CHN-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.29142,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-27","TRTSDTM":"2019-10-29 08:14:32","TRT01SDTM":"2019-10-29 08:14:32","AP01SDTM":"2019-10-29 08:14:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6742,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03363,"AVALU":"g/L","BASE2":3.03363,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"3","BTOXGR":"0","ADTM":"2019-12-10 08:14:32","ADY":42,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-266","SUBJID":"id-266","SITEID":"CHN-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.29142,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-27","TRTSDTM":"2019-10-29 08:14:32","TRT01SDTM":"2019-10-29 08:14:32","AP01SDTM":"2019-10-29 08:14:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":102,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94499,"AVALU":"g/L","BASE2":3.03363,"BASE":2.94499,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.08864,"PCHG2":-2.92188,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-03 08:14:32","ADY":126,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-266","SUBJID":"id-266","SITEID":"CHN-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.29142,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-27","TRTSDTM":"2019-10-29 08:14:32","TRT01SDTM":"2019-10-29 08:14:32","AP01SDTM":"2019-10-29 08:14:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":791,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82384,"AVALU":"g/L","BASE2":3.03363,"BASE":2.94499,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20979,"PCHG2":-6.91553,"CHG":-0.12115,"PCHG":-4.11385,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-04 08:14:32","ADY":158,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-266","SUBJID":"id-266","SITEID":"CHN-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.29142,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-27","TRTSDTM":"2019-10-29 08:14:32","TRT01SDTM":"2019-10-29 08:14:32","AP01SDTM":"2019-10-29 08:14:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6919,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00147,"AVALU":"g/L","BASE2":3.03363,"BASE":2.94499,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03216,"PCHG2":-1.06006,"CHG":0.05648,"PCHG":1.91786,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-04-07 08:14:32","ADY":161,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-266","SUBJID":"id-266","SITEID":"CHN-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.29142,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-27","TRTSDTM":"2019-10-29 08:14:32","TRT01SDTM":"2019-10-29 08:14:32","AP01SDTM":"2019-10-29 08:14:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":430,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99352,"AVALU":"g/L","BASE2":3.03363,"BASE":2.94499,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04011,"PCHG2":-1.32214,"CHG":0.04853,"PCHG":1.6479,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-04 08:14:32","ADY":372,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-266","SUBJID":"id-266","SITEID":"CHN-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.29142,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-27","TRTSDTM":"2019-10-29 08:14:32","TRT01SDTM":"2019-10-29 08:14:32","AP01SDTM":"2019-10-29 08:14:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6523,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96311,"AVALU":"g/L","BASE2":3.03363,"BASE":2.94499,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07052,"PCHG2":-2.32453,"CHG":0.01812,"PCHG":0.61533,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-22 08:14:32","ADY":451,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-266","SUBJID":"id-266","SITEID":"CHN-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":11.29142,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-27","TRTSDTM":"2019-10-29 08:14:32","TRT01SDTM":"2019-10-29 08:14:32","AP01SDTM":"2019-10-29 08:14:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2085,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93783,"AVALU":"g/L","BASE2":3.03363,"BASE":2.94499,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09579,"PCHG2":-3.15776,"CHG":-0.00716,"PCHG":-0.24298,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-17 08:14:32","ADY":566,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-285","SUBJID":"id-285","SITEID":"CHN-12","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.79676,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-24","TRTSDTM":"2020-09-27 19:18:10","TRTEDTM":"2023-09-28 13:18:10","TRT01SDTM":"2020-09-27 19:18:10","TRT01EDTM":"2022-09-28 07:18:10","TRT02SDTM":"2022-09-28 07:18:10","TRT02EDTM":"2023-09-28 13:18:10","AP01SDTM":"2020-09-27 19:18:10","AP01EDTM":"2022-09-28 07:18:10","AP02SDTM":"2022-09-28 07:18:10","AP02EDTM":"2023-09-28 13:18:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-28","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5237,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.97041,"AVALU":"U/L","BASE2":32.97041,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-08 19:18:10","ADY":134,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-285","SUBJID":"id-285","SITEID":"CHN-12","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.79676,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-24","TRTSDTM":"2020-09-27 19:18:10","TRTEDTM":"2023-09-28 13:18:10","TRT01SDTM":"2020-09-27 19:18:10","TRT01EDTM":"2022-09-28 07:18:10","TRT02SDTM":"2022-09-28 07:18:10","TRT02EDTM":"2023-09-28 13:18:10","AP01SDTM":"2020-09-27 19:18:10","AP01EDTM":"2022-09-28 07:18:10","AP02SDTM":"2022-09-28 07:18:10","AP02EDTM":"2023-09-28 13:18:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-28","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8259,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.593,"AVALU":"U/L","BASE2":32.97041,"BASE":21.593,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-11.37741,"PCHG2":-34.50795,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-19 19:18:10","ADY":173,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-285","SUBJID":"id-285","SITEID":"CHN-12","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.79676,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-24","TRTSDTM":"2020-09-27 19:18:10","TRTEDTM":"2023-09-28 13:18:10","TRT01SDTM":"2020-09-27 19:18:10","TRT01EDTM":"2022-09-28 07:18:10","TRT02SDTM":"2022-09-28 07:18:10","TRT02EDTM":"2023-09-28 13:18:10","AP01SDTM":"2020-09-27 19:18:10","AP01EDTM":"2022-09-28 07:18:10","AP02SDTM":"2022-09-28 07:18:10","AP02EDTM":"2023-09-28 13:18:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-28","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7046,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.6255,"AVALU":"U/L","BASE2":32.97041,"BASE":21.593,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.34491,"PCHG2":-19.24426,"CHG":5.0325,"PCHG":23.30618,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-24 19:18:10","ADY":178,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-285","SUBJID":"id-285","SITEID":"CHN-12","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.79676,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-24","TRTSDTM":"2020-09-27 19:18:10","TRTEDTM":"2023-09-28 13:18:10","TRT01SDTM":"2020-09-27 19:18:10","TRT01EDTM":"2022-09-28 07:18:10","TRT02SDTM":"2022-09-28 07:18:10","TRT02EDTM":"2023-09-28 13:18:10","AP01SDTM":"2020-09-27 19:18:10","AP01EDTM":"2022-09-28 07:18:10","AP02SDTM":"2022-09-28 07:18:10","AP02EDTM":"2023-09-28 13:18:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-28","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4017,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.00607,"AVALU":"U/L","BASE2":32.97041,"BASE":21.593,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-29.96434,"PCHG2":-90.88251,"CHG":-18.58692,"PCHG":-86.07847,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-10-10 19:18:10","ADY":378,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-285","SUBJID":"id-285","SITEID":"CHN-12","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.79676,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-24","TRTSDTM":"2020-09-27 19:18:10","TRTEDTM":"2023-09-28 13:18:10","TRT01SDTM":"2020-09-27 19:18:10","TRT01EDTM":"2022-09-28 07:18:10","TRT02SDTM":"2022-09-28 07:18:10","TRT02EDTM":"2023-09-28 13:18:10","AP01SDTM":"2020-09-27 19:18:10","AP01EDTM":"2022-09-28 07:18:10","AP02SDTM":"2022-09-28 07:18:10","AP02EDTM":"2023-09-28 13:18:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-28","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1942,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.68927,"AVALU":"U/L","BASE2":32.97041,"BASE":21.593,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.28114,"PCHG2":-25.11688,"CHG":3.09628,"PCHG":14.33926,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-28 19:18:10","ADY":547,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-285","SUBJID":"id-285","SITEID":"CHN-12","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.79676,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-24","TRTSDTM":"2020-09-27 19:18:10","TRTEDTM":"2023-09-28 13:18:10","TRT01SDTM":"2020-09-27 19:18:10","TRT01EDTM":"2022-09-28 07:18:10","TRT02SDTM":"2022-09-28 07:18:10","TRT02EDTM":"2023-09-28 13:18:10","AP01SDTM":"2020-09-27 19:18:10","AP01EDTM":"2022-09-28 07:18:10","AP02SDTM":"2022-09-28 07:18:10","AP02EDTM":"2023-09-28 13:18:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-28","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4500,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.26824,"AVALU":"U/L","BASE2":32.97041,"BASE":21.593,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-29.70217,"PCHG2":-90.08734,"CHG":-18.32475,"PCHG":-84.86433,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-09-27 19:18:10","ADY":730,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-285","SUBJID":"id-285","SITEID":"CHN-12","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.79676,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-24","TRTSDTM":"2020-09-27 19:18:10","TRTEDTM":"2023-09-28 13:18:10","TRT01SDTM":"2020-09-27 19:18:10","TRT01EDTM":"2022-09-28 07:18:10","TRT02SDTM":"2022-09-28 07:18:10","TRT02EDTM":"2023-09-28 13:18:10","AP01SDTM":"2020-09-27 19:18:10","AP01EDTM":"2022-09-28 07:18:10","AP02SDTM":"2022-09-28 07:18:10","AP02EDTM":"2023-09-28 13:18:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-28","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3390,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.56532,"AVALU":"U/L","BASE2":32.97041,"BASE":21.593,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-18.40509,"PCHG2":-55.82305,"CHG":-7.02768,"PCHG":-32.54609,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-02 19:18:10","ADY":796,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-285","SUBJID":"id-285","SITEID":"CHN-12","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.79676,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-24","TRTSDTM":"2020-09-27 19:18:10","TRTEDTM":"2023-09-28 13:18:10","TRT01SDTM":"2020-09-27 19:18:10","TRT01EDTM":"2022-09-28 07:18:10","TRT02SDTM":"2022-09-28 07:18:10","TRT02EDTM":"2023-09-28 13:18:10","AP01SDTM":"2020-09-27 19:18:10","AP01EDTM":"2022-09-28 07:18:10","AP02SDTM":"2022-09-28 07:18:10","AP02EDTM":"2023-09-28 13:18:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-28","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2213,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.11931,"AVALU":"mg/L","BASE2":8.11931,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-08 19:18:10","ADY":134,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-285","SUBJID":"id-285","SITEID":"CHN-12","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.79676,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-24","TRTSDTM":"2020-09-27 19:18:10","TRTEDTM":"2023-09-28 13:18:10","TRT01SDTM":"2020-09-27 19:18:10","TRT01EDTM":"2022-09-28 07:18:10","TRT02SDTM":"2022-09-28 07:18:10","TRT02EDTM":"2023-09-28 13:18:10","AP01SDTM":"2020-09-27 19:18:10","AP01EDTM":"2022-09-28 07:18:10","AP02SDTM":"2022-09-28 07:18:10","AP02EDTM":"2023-09-28 13:18:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-28","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4431,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.33338,"AVALU":"mg/L","BASE2":8.11931,"BASE":8.33338,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.21407,"PCHG2":2.63653,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-19 19:18:10","ADY":173,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-285","SUBJID":"id-285","SITEID":"CHN-12","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.79676,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-24","TRTSDTM":"2020-09-27 19:18:10","TRTEDTM":"2023-09-28 13:18:10","TRT01SDTM":"2020-09-27 19:18:10","TRT01EDTM":"2022-09-28 07:18:10","TRT02SDTM":"2022-09-28 07:18:10","TRT02EDTM":"2023-09-28 13:18:10","AP01SDTM":"2020-09-27 19:18:10","AP01EDTM":"2022-09-28 07:18:10","AP02SDTM":"2022-09-28 07:18:10","AP02EDTM":"2023-09-28 13:18:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-28","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3656,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.0762,"AVALU":"mg/L","BASE2":8.11931,"BASE":8.33338,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.95689,"PCHG2":24.10163,"CHG":1.74282,"PCHG":20.9137,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-03-24 19:18:10","ADY":178,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-285","SUBJID":"id-285","SITEID":"CHN-12","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.79676,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-24","TRTSDTM":"2020-09-27 19:18:10","TRTEDTM":"2023-09-28 13:18:10","TRT01SDTM":"2020-09-27 19:18:10","TRT01EDTM":"2022-09-28 07:18:10","TRT02SDTM":"2022-09-28 07:18:10","TRT02EDTM":"2023-09-28 13:18:10","AP01SDTM":"2020-09-27 19:18:10","AP01EDTM":"2022-09-28 07:18:10","AP02SDTM":"2022-09-28 07:18:10","AP02EDTM":"2023-09-28 13:18:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-28","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7729,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.14846,"AVALU":"mg/L","BASE2":8.11931,"BASE":8.33338,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.02915,"PCHG2":24.99159,"CHG":1.81508,"PCHG":21.7808,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-10-10 19:18:10","ADY":378,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-285","SUBJID":"id-285","SITEID":"CHN-12","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.79676,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-24","TRTSDTM":"2020-09-27 19:18:10","TRTEDTM":"2023-09-28 13:18:10","TRT01SDTM":"2020-09-27 19:18:10","TRT01EDTM":"2022-09-28 07:18:10","TRT02SDTM":"2022-09-28 07:18:10","TRT02EDTM":"2023-09-28 13:18:10","AP01SDTM":"2020-09-27 19:18:10","AP01EDTM":"2022-09-28 07:18:10","AP02SDTM":"2022-09-28 07:18:10","AP02EDTM":"2023-09-28 13:18:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-28","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7736,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.86917,"AVALU":"mg/L","BASE2":8.11931,"BASE":8.33338,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.74985,"PCHG2":9.23544,"CHG":0.53579,"PCHG":6.4294,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-28 19:18:10","ADY":547,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-285","SUBJID":"id-285","SITEID":"CHN-12","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.79676,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-24","TRTSDTM":"2020-09-27 19:18:10","TRTEDTM":"2023-09-28 13:18:10","TRT01SDTM":"2020-09-27 19:18:10","TRT01EDTM":"2022-09-28 07:18:10","TRT02SDTM":"2022-09-28 07:18:10","TRT02EDTM":"2023-09-28 13:18:10","AP01SDTM":"2020-09-27 19:18:10","AP01EDTM":"2022-09-28 07:18:10","AP02SDTM":"2022-09-28 07:18:10","AP02EDTM":"2023-09-28 13:18:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-28","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6103,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.6759,"AVALU":"mg/L","BASE2":8.11931,"BASE":8.33338,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.55659,"PCHG2":19.17146,"CHG":1.34252,"PCHG":16.11018,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-27 19:18:10","ADY":730,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-285","SUBJID":"id-285","SITEID":"CHN-12","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.79676,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-24","TRTSDTM":"2020-09-27 19:18:10","TRTEDTM":"2023-09-28 13:18:10","TRT01SDTM":"2020-09-27 19:18:10","TRT01EDTM":"2022-09-28 07:18:10","TRT02SDTM":"2022-09-28 07:18:10","TRT02EDTM":"2023-09-28 13:18:10","AP01SDTM":"2020-09-27 19:18:10","AP01EDTM":"2022-09-28 07:18:10","AP02SDTM":"2022-09-28 07:18:10","AP02EDTM":"2023-09-28 13:18:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-28","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7469,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.07246,"AVALU":"mg/L","BASE2":8.11931,"BASE":8.33338,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04685,"PCHG2":-0.57705,"CHG":-0.26092,"PCHG":-3.13103,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-02 19:18:10","ADY":796,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-285","SUBJID":"id-285","SITEID":"CHN-12","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.79676,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-24","TRTSDTM":"2020-09-27 19:18:10","TRTEDTM":"2023-09-28 13:18:10","TRT01SDTM":"2020-09-27 19:18:10","TRT01EDTM":"2022-09-28 07:18:10","TRT02SDTM":"2022-09-28 07:18:10","TRT02EDTM":"2023-09-28 13:18:10","AP01SDTM":"2020-09-27 19:18:10","AP01EDTM":"2022-09-28 07:18:10","AP02SDTM":"2022-09-28 07:18:10","AP02EDTM":"2023-09-28 13:18:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-28","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4978,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82445,"AVALU":"g/L","BASE2":2.82445,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-08 19:18:10","ADY":134,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-285","SUBJID":"id-285","SITEID":"CHN-12","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.79676,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-24","TRTSDTM":"2020-09-27 19:18:10","TRTEDTM":"2023-09-28 13:18:10","TRT01SDTM":"2020-09-27 19:18:10","TRT01EDTM":"2022-09-28 07:18:10","TRT02SDTM":"2022-09-28 07:18:10","TRT02EDTM":"2023-09-28 13:18:10","AP01SDTM":"2020-09-27 19:18:10","AP01EDTM":"2022-09-28 07:18:10","AP02SDTM":"2022-09-28 07:18:10","AP02EDTM":"2023-09-28 13:18:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-28","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3791,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8058,"AVALU":"g/L","BASE2":2.82445,"BASE":2.8058,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.01866,"PCHG2":-0.66056,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-19 19:18:10","ADY":173,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-285","SUBJID":"id-285","SITEID":"CHN-12","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.79676,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-24","TRTSDTM":"2020-09-27 19:18:10","TRTEDTM":"2023-09-28 13:18:10","TRT01SDTM":"2020-09-27 19:18:10","TRT01EDTM":"2022-09-28 07:18:10","TRT02SDTM":"2022-09-28 07:18:10","TRT02EDTM":"2023-09-28 13:18:10","AP01SDTM":"2020-09-27 19:18:10","AP01EDTM":"2022-09-28 07:18:10","AP02SDTM":"2022-09-28 07:18:10","AP02EDTM":"2023-09-28 13:18:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-28","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5290,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04909,"AVALU":"g/L","BASE2":2.82445,"BASE":2.8058,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.22464,"PCHG2":7.95326,"CHG":0.24329,"PCHG":8.67109,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-03-24 19:18:10","ADY":178,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-285","SUBJID":"id-285","SITEID":"CHN-12","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.79676,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-24","TRTSDTM":"2020-09-27 19:18:10","TRTEDTM":"2023-09-28 13:18:10","TRT01SDTM":"2020-09-27 19:18:10","TRT01EDTM":"2022-09-28 07:18:10","TRT02SDTM":"2022-09-28 07:18:10","TRT02EDTM":"2023-09-28 13:18:10","AP01SDTM":"2020-09-27 19:18:10","AP01EDTM":"2022-09-28 07:18:10","AP02SDTM":"2022-09-28 07:18:10","AP02EDTM":"2023-09-28 13:18:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-28","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":319,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0655,"AVALU":"g/L","BASE2":2.82445,"BASE":2.8058,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.24105,"PCHG2":8.53427,"CHG":0.2597,"PCHG":9.25597,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-10-10 19:18:10","ADY":378,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-285","SUBJID":"id-285","SITEID":"CHN-12","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.79676,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-24","TRTSDTM":"2020-09-27 19:18:10","TRTEDTM":"2023-09-28 13:18:10","TRT01SDTM":"2020-09-27 19:18:10","TRT01EDTM":"2022-09-28 07:18:10","TRT02SDTM":"2022-09-28 07:18:10","TRT02EDTM":"2023-09-28 13:18:10","AP01SDTM":"2020-09-27 19:18:10","AP01EDTM":"2022-09-28 07:18:10","AP02SDTM":"2022-09-28 07:18:10","AP02EDTM":"2023-09-28 13:18:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-28","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7279,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91365,"AVALU":"g/L","BASE2":2.82445,"BASE":2.8058,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08919,"PCHG2":3.15794,"CHG":0.10785,"PCHG":3.84388,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-28 19:18:10","ADY":547,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-285","SUBJID":"id-285","SITEID":"CHN-12","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.79676,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-24","TRTSDTM":"2020-09-27 19:18:10","TRTEDTM":"2023-09-28 13:18:10","TRT01SDTM":"2020-09-27 19:18:10","TRT01EDTM":"2022-09-28 07:18:10","TRT02SDTM":"2022-09-28 07:18:10","TRT02EDTM":"2023-09-28 13:18:10","AP01SDTM":"2020-09-27 19:18:10","AP01EDTM":"2022-09-28 07:18:10","AP02SDTM":"2022-09-28 07:18:10","AP02EDTM":"2023-09-28 13:18:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-28","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5335,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.09082,"AVALU":"g/L","BASE2":2.82445,"BASE":2.8058,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.26637,"PCHG2":9.43075,"CHG":0.28502,"PCHG":10.15841,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-09-27 19:18:10","ADY":730,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-285","SUBJID":"id-285","SITEID":"CHN-12","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.79676,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-24","TRTSDTM":"2020-09-27 19:18:10","TRTEDTM":"2023-09-28 13:18:10","TRT01SDTM":"2020-09-27 19:18:10","TRT01EDTM":"2022-09-28 07:18:10","TRT02SDTM":"2022-09-28 07:18:10","TRT02EDTM":"2023-09-28 13:18:10","AP01SDTM":"2020-09-27 19:18:10","AP01EDTM":"2022-09-28 07:18:10","AP02SDTM":"2022-09-28 07:18:10","AP02EDTM":"2023-09-28 13:18:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-28","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3803,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95993,"AVALU":"g/L","BASE2":2.82445,"BASE":2.8058,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13548,"PCHG2":4.79661,"CHG":0.15414,"PCHG":5.49345,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-02 19:18:10","ADY":796,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-294","SUBJID":"id-294","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.67351,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-10 11:00:57","TRTEDTM":"2022-02-14 04:54:16","TRT01SDTM":"2020-10-10 11:00:57","TRT01EDTM":"2021-02-13 22:54:16","TRT02SDTM":"2021-02-13 22:54:16","TRT02EDTM":"2022-02-14 04:54:16","AP01SDTM":"2020-10-10 11:00:57","AP01EDTM":"2021-02-13 22:54:16","AP02SDTM":"2021-02-13 22:54:16","AP02EDTM":"2022-02-14 04:54:16","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":492,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-09","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4200,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.35964,"AVALU":"U/L","BASE2":9.35964,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-16 11:00:57","ADY":6,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-294","SUBJID":"id-294","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.67351,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-10 11:00:57","TRTEDTM":"2022-02-14 04:54:16","TRT01SDTM":"2020-10-10 11:00:57","TRT01EDTM":"2021-02-13 22:54:16","TRT02SDTM":"2021-02-13 22:54:16","TRT02EDTM":"2022-02-14 04:54:16","AP01SDTM":"2020-10-10 11:00:57","AP01EDTM":"2021-02-13 22:54:16","AP02SDTM":"2021-02-13 22:54:16","AP02EDTM":"2022-02-14 04:54:16","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":492,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-09","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2724,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.38038,"AVALU":"U/L","BASE2":9.35964,"BASE":13.38038,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":4.02074,"PCHG2":42.95823,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-24 11:00:57","ADY":165,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-294","SUBJID":"id-294","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.67351,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-10 11:00:57","TRTEDTM":"2022-02-14 04:54:16","TRT01SDTM":"2020-10-10 11:00:57","TRT01EDTM":"2021-02-13 22:54:16","TRT02SDTM":"2021-02-13 22:54:16","TRT02EDTM":"2022-02-14 04:54:16","AP01SDTM":"2020-10-10 11:00:57","AP01EDTM":"2021-02-13 22:54:16","AP02SDTM":"2021-02-13 22:54:16","AP02EDTM":"2022-02-14 04:54:16","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":492,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-09","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2347,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":39.88532,"AVALU":"U/L","BASE2":9.35964,"BASE":13.38038,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":30.52567,"PCHG2":326.14153,"CHG":26.50494,"PCHG":198.08814,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-12 11:00:57","ADY":275,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-294","SUBJID":"id-294","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.67351,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-10 11:00:57","TRTEDTM":"2022-02-14 04:54:16","TRT01SDTM":"2020-10-10 11:00:57","TRT01EDTM":"2021-02-13 22:54:16","TRT02SDTM":"2021-02-13 22:54:16","TRT02EDTM":"2022-02-14 04:54:16","AP01SDTM":"2020-10-10 11:00:57","AP01EDTM":"2021-02-13 22:54:16","AP02SDTM":"2021-02-13 22:54:16","AP02EDTM":"2022-02-14 04:54:16","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":492,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-09","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1719,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.97232,"AVALU":"U/L","BASE2":9.35964,"BASE":13.38038,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":17.61268,"PCHG2":188.17686,"CHG":13.59194,"PCHG":101.58116,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-30 11:00:57","ADY":385,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-294","SUBJID":"id-294","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.67351,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-10 11:00:57","TRTEDTM":"2022-02-14 04:54:16","TRT01SDTM":"2020-10-10 11:00:57","TRT01EDTM":"2021-02-13 22:54:16","TRT02SDTM":"2021-02-13 22:54:16","TRT02EDTM":"2022-02-14 04:54:16","AP01SDTM":"2020-10-10 11:00:57","AP01EDTM":"2021-02-13 22:54:16","AP02SDTM":"2021-02-13 22:54:16","AP02EDTM":"2022-02-14 04:54:16","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":492,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-09","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6134,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.37422,"AVALU":"U/L","BASE2":9.35964,"BASE":13.38038,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.01458,"PCHG2":139.04996,"CHG":8.99384,"PCHG":67.21665,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-04 11:00:57","ADY":390,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-294","SUBJID":"id-294","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.67351,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-10 11:00:57","TRTEDTM":"2022-02-14 04:54:16","TRT01SDTM":"2020-10-10 11:00:57","TRT01EDTM":"2021-02-13 22:54:16","TRT02SDTM":"2021-02-13 22:54:16","TRT02EDTM":"2022-02-14 04:54:16","AP01SDTM":"2020-10-10 11:00:57","AP01EDTM":"2021-02-13 22:54:16","AP02SDTM":"2021-02-13 22:54:16","AP02EDTM":"2022-02-14 04:54:16","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":492,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-09","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3615,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.18466,"AVALU":"U/L","BASE2":9.35964,"BASE":13.38038,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.82502,"PCHG2":137.02466,"CHG":8.80428,"PCHG":65.79994,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-02 11:00:57","ADY":418,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-294","SUBJID":"id-294","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.67351,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-10 11:00:57","TRTEDTM":"2022-02-14 04:54:16","TRT01SDTM":"2020-10-10 11:00:57","TRT01EDTM":"2021-02-13 22:54:16","TRT02SDTM":"2021-02-13 22:54:16","TRT02EDTM":"2022-02-14 04:54:16","AP01SDTM":"2020-10-10 11:00:57","AP01EDTM":"2021-02-13 22:54:16","AP02SDTM":"2021-02-13 22:54:16","AP02EDTM":"2022-02-14 04:54:16","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":492,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-09","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5332,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.9944,"AVALU":"U/L","BASE2":9.35964,"BASE":13.38038,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.63476,"PCHG2":60.20277,"CHG":1.61403,"PCHG":12.06264,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-14 11:00:57","ADY":461,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-294","SUBJID":"id-294","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.67351,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-10 11:00:57","TRTEDTM":"2022-02-14 04:54:16","TRT01SDTM":"2020-10-10 11:00:57","TRT01EDTM":"2021-02-13 22:54:16","TRT02SDTM":"2021-02-13 22:54:16","TRT02EDTM":"2022-02-14 04:54:16","AP01SDTM":"2020-10-10 11:00:57","AP01EDTM":"2021-02-13 22:54:16","AP02SDTM":"2021-02-13 22:54:16","AP02EDTM":"2022-02-14 04:54:16","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":492,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-09","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3519,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.23398,"AVALU":"mg/L","BASE2":8.23398,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-16 11:00:57","ADY":6,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-294","SUBJID":"id-294","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.67351,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-10 11:00:57","TRTEDTM":"2022-02-14 04:54:16","TRT01SDTM":"2020-10-10 11:00:57","TRT01EDTM":"2021-02-13 22:54:16","TRT02SDTM":"2021-02-13 22:54:16","TRT02EDTM":"2022-02-14 04:54:16","AP01SDTM":"2020-10-10 11:00:57","AP01EDTM":"2021-02-13 22:54:16","AP02SDTM":"2021-02-13 22:54:16","AP02EDTM":"2022-02-14 04:54:16","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":492,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-09","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7692,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.27874,"AVALU":"mg/L","BASE2":8.23398,"BASE":8.27874,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.04475,"PCHG2":0.54352,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-24 11:00:57","ADY":165,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-294","SUBJID":"id-294","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.67351,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-10 11:00:57","TRTEDTM":"2022-02-14 04:54:16","TRT01SDTM":"2020-10-10 11:00:57","TRT01EDTM":"2021-02-13 22:54:16","TRT02SDTM":"2021-02-13 22:54:16","TRT02EDTM":"2022-02-14 04:54:16","AP01SDTM":"2020-10-10 11:00:57","AP01EDTM":"2021-02-13 22:54:16","AP02SDTM":"2021-02-13 22:54:16","AP02EDTM":"2022-02-14 04:54:16","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":492,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-09","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2839,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.99844,"AVALU":"mg/L","BASE2":8.23398,"BASE":8.27874,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.23555,"PCHG2":-2.86066,"CHG":-0.2803,"PCHG":-3.38578,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-07-12 11:00:57","ADY":275,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-294","SUBJID":"id-294","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.67351,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-10 11:00:57","TRTEDTM":"2022-02-14 04:54:16","TRT01SDTM":"2020-10-10 11:00:57","TRT01EDTM":"2021-02-13 22:54:16","TRT02SDTM":"2021-02-13 22:54:16","TRT02EDTM":"2022-02-14 04:54:16","AP01SDTM":"2020-10-10 11:00:57","AP01EDTM":"2021-02-13 22:54:16","AP02SDTM":"2021-02-13 22:54:16","AP02EDTM":"2022-02-14 04:54:16","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":492,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-09","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":877,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.25363,"AVALU":"mg/L","BASE2":8.23398,"BASE":8.27874,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.01964,"PCHG2":12.38334,"CHG":0.97489,"PCHG":11.77581,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-30 11:00:57","ADY":385,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-294","SUBJID":"id-294","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.67351,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-10 11:00:57","TRTEDTM":"2022-02-14 04:54:16","TRT01SDTM":"2020-10-10 11:00:57","TRT01EDTM":"2021-02-13 22:54:16","TRT02SDTM":"2021-02-13 22:54:16","TRT02EDTM":"2022-02-14 04:54:16","AP01SDTM":"2020-10-10 11:00:57","AP01EDTM":"2021-02-13 22:54:16","AP02SDTM":"2021-02-13 22:54:16","AP02EDTM":"2022-02-14 04:54:16","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":492,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-09","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":333,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.24475,"AVALU":"mg/L","BASE2":8.23398,"BASE":8.27874,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.01077,"PCHG2":36.56517,"CHG":2.96602,"PCHG":35.82692,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-11-04 11:00:57","ADY":390,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-294","SUBJID":"id-294","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.67351,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-10 11:00:57","TRTEDTM":"2022-02-14 04:54:16","TRT01SDTM":"2020-10-10 11:00:57","TRT01EDTM":"2021-02-13 22:54:16","TRT02SDTM":"2021-02-13 22:54:16","TRT02EDTM":"2022-02-14 04:54:16","AP01SDTM":"2020-10-10 11:00:57","AP01EDTM":"2021-02-13 22:54:16","AP02SDTM":"2021-02-13 22:54:16","AP02EDTM":"2022-02-14 04:54:16","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":492,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-09","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5608,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.37721,"AVALU":"mg/L","BASE2":8.23398,"BASE":8.27874,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14323,"PCHG2":1.73952,"CHG":0.09848,"PCHG":1.18953,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-02 11:00:57","ADY":418,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-294","SUBJID":"id-294","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.67351,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-10 11:00:57","TRTEDTM":"2022-02-14 04:54:16","TRT01SDTM":"2020-10-10 11:00:57","TRT01EDTM":"2021-02-13 22:54:16","TRT02SDTM":"2021-02-13 22:54:16","TRT02EDTM":"2022-02-14 04:54:16","AP01SDTM":"2020-10-10 11:00:57","AP01EDTM":"2021-02-13 22:54:16","AP02SDTM":"2021-02-13 22:54:16","AP02EDTM":"2022-02-14 04:54:16","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":492,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-09","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3719,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.77229,"AVALU":"mg/L","BASE2":8.23398,"BASE":8.27874,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.53831,"PCHG2":18.68243,"CHG":1.49355,"PCHG":18.04085,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-14 11:00:57","ADY":461,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-294","SUBJID":"id-294","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.67351,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-10 11:00:57","TRTEDTM":"2022-02-14 04:54:16","TRT01SDTM":"2020-10-10 11:00:57","TRT01EDTM":"2021-02-13 22:54:16","TRT02SDTM":"2021-02-13 22:54:16","TRT02EDTM":"2022-02-14 04:54:16","AP01SDTM":"2020-10-10 11:00:57","AP01EDTM":"2021-02-13 22:54:16","AP02SDTM":"2021-02-13 22:54:16","AP02EDTM":"2022-02-14 04:54:16","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":492,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-09","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4984,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96159,"AVALU":"g/L","BASE2":2.96159,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-16 11:00:57","ADY":6,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-294","SUBJID":"id-294","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.67351,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-10 11:00:57","TRTEDTM":"2022-02-14 04:54:16","TRT01SDTM":"2020-10-10 11:00:57","TRT01EDTM":"2021-02-13 22:54:16","TRT02SDTM":"2021-02-13 22:54:16","TRT02EDTM":"2022-02-14 04:54:16","AP01SDTM":"2020-10-10 11:00:57","AP01EDTM":"2021-02-13 22:54:16","AP02SDTM":"2021-02-13 22:54:16","AP02EDTM":"2022-02-14 04:54:16","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":492,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-09","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7567,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77064,"AVALU":"g/L","BASE2":2.96159,"BASE":2.77064,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.19095,"PCHG2":-6.44745,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-24 11:00:57","ADY":165,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-294","SUBJID":"id-294","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.67351,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-10 11:00:57","TRTEDTM":"2022-02-14 04:54:16","TRT01SDTM":"2020-10-10 11:00:57","TRT01EDTM":"2021-02-13 22:54:16","TRT02SDTM":"2021-02-13 22:54:16","TRT02EDTM":"2022-02-14 04:54:16","AP01SDTM":"2020-10-10 11:00:57","AP01EDTM":"2021-02-13 22:54:16","AP02SDTM":"2021-02-13 22:54:16","AP02EDTM":"2022-02-14 04:54:16","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":492,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-09","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8002,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9857,"AVALU":"g/L","BASE2":2.96159,"BASE":2.77064,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02411,"PCHG2":0.81411,"CHG":0.21506,"PCHG":7.76201,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-12 11:00:57","ADY":275,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-294","SUBJID":"id-294","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.67351,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-10 11:00:57","TRTEDTM":"2022-02-14 04:54:16","TRT01SDTM":"2020-10-10 11:00:57","TRT01EDTM":"2021-02-13 22:54:16","TRT02SDTM":"2021-02-13 22:54:16","TRT02EDTM":"2022-02-14 04:54:16","AP01SDTM":"2020-10-10 11:00:57","AP01EDTM":"2021-02-13 22:54:16","AP02SDTM":"2021-02-13 22:54:16","AP02EDTM":"2022-02-14 04:54:16","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":492,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-09","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2344,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9948,"AVALU":"g/L","BASE2":2.96159,"BASE":2.77064,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03321,"PCHG2":1.12146,"CHG":0.22416,"PCHG":8.09054,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-30 11:00:57","ADY":385,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-294","SUBJID":"id-294","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.67351,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-10 11:00:57","TRTEDTM":"2022-02-14 04:54:16","TRT01SDTM":"2020-10-10 11:00:57","TRT01EDTM":"2021-02-13 22:54:16","TRT02SDTM":"2021-02-13 22:54:16","TRT02EDTM":"2022-02-14 04:54:16","AP01SDTM":"2020-10-10 11:00:57","AP01EDTM":"2021-02-13 22:54:16","AP02SDTM":"2021-02-13 22:54:16","AP02EDTM":"2022-02-14 04:54:16","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":492,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-09","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1408,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8571,"AVALU":"g/L","BASE2":2.96159,"BASE":2.77064,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10449,"PCHG2":-3.52803,"CHG":0.08646,"PCHG":3.12062,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-04 11:00:57","ADY":390,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-294","SUBJID":"id-294","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.67351,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-10 11:00:57","TRTEDTM":"2022-02-14 04:54:16","TRT01SDTM":"2020-10-10 11:00:57","TRT01EDTM":"2021-02-13 22:54:16","TRT02SDTM":"2021-02-13 22:54:16","TRT02EDTM":"2022-02-14 04:54:16","AP01SDTM":"2020-10-10 11:00:57","AP01EDTM":"2021-02-13 22:54:16","AP02SDTM":"2021-02-13 22:54:16","AP02EDTM":"2022-02-14 04:54:16","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":492,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-09","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6638,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88873,"AVALU":"g/L","BASE2":2.96159,"BASE":2.77064,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07286,"PCHG2":-2.46004,"CHG":0.11809,"PCHG":4.26221,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-02 11:00:57","ADY":418,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-294","SUBJID":"id-294","SITEID":"CHN-12","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.67351,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-09","TRTSDTM":"2020-10-10 11:00:57","TRTEDTM":"2022-02-14 04:54:16","TRT01SDTM":"2020-10-10 11:00:57","TRT01EDTM":"2021-02-13 22:54:16","TRT02SDTM":"2021-02-13 22:54:16","TRT02EDTM":"2022-02-14 04:54:16","AP01SDTM":"2020-10-10 11:00:57","AP01EDTM":"2021-02-13 22:54:16","AP02SDTM":"2021-02-13 22:54:16","AP02EDTM":"2022-02-14 04:54:16","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":492,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-09","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3044,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.63108,"AVALU":"g/L","BASE2":2.96159,"BASE":2.77064,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.33051,"PCHG2":-11.15993,"CHG":-0.13956,"PCHG":-5.03726,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-14 11:00:57","ADY":461,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-322","SUBJID":"id-322","SITEID":"CHN-12","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.28899,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-01","TRTSDTM":"2019-07-04 15:06:11","TRTEDTM":"2022-07-04 09:06:11","TRT01SDTM":"2019-07-04 15:06:11","TRT01EDTM":"2021-07-04 03:06:11","TRT02SDTM":"2021-07-04 03:06:11","TRT02EDTM":"2022-07-04 09:06:11","AP01SDTM":"2019-07-04 15:06:11","AP01EDTM":"2021-07-04 03:06:11","AP02SDTM":"2021-07-04 03:06:11","AP02EDTM":"2022-07-04 09:06:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-04","EOSDY":1096,"LSTALVDT":"2022-07-24","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6751,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":42.01618,"AVALU":"U/L","BASE2":42.01618,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-27 15:06:11","ADY":85,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-322","SUBJID":"id-322","SITEID":"CHN-12","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.28899,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-01","TRTSDTM":"2019-07-04 15:06:11","TRTEDTM":"2022-07-04 09:06:11","TRT01SDTM":"2019-07-04 15:06:11","TRT01EDTM":"2021-07-04 03:06:11","TRT02SDTM":"2021-07-04 03:06:11","TRT02EDTM":"2022-07-04 09:06:11","AP01SDTM":"2019-07-04 15:06:11","AP01EDTM":"2021-07-04 03:06:11","AP02SDTM":"2021-07-04 03:06:11","AP02EDTM":"2022-07-04 09:06:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-04","EOSDY":1096,"LSTALVDT":"2022-07-24","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2310,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.7347,"AVALU":"U/L","BASE2":42.01618,"BASE":13.7347,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-28.28148,"PCHG2":-67.31092,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-13 15:06:11","ADY":284,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-322","SUBJID":"id-322","SITEID":"CHN-12","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.28899,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-01","TRTSDTM":"2019-07-04 15:06:11","TRTEDTM":"2022-07-04 09:06:11","TRT01SDTM":"2019-07-04 15:06:11","TRT01EDTM":"2021-07-04 03:06:11","TRT02SDTM":"2021-07-04 03:06:11","TRT02EDTM":"2022-07-04 09:06:11","AP01SDTM":"2019-07-04 15:06:11","AP01EDTM":"2021-07-04 03:06:11","AP02SDTM":"2021-07-04 03:06:11","AP02EDTM":"2022-07-04 09:06:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-04","EOSDY":1096,"LSTALVDT":"2022-07-24","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3561,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.11398,"AVALU":"U/L","BASE2":42.01618,"BASE":13.7347,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.9022,"PCHG2":-28.32766,"CHG":16.37927,"PCHG":119.25468,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-25 15:06:11","ADY":296,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-322","SUBJID":"id-322","SITEID":"CHN-12","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.28899,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-01","TRTSDTM":"2019-07-04 15:06:11","TRTEDTM":"2022-07-04 09:06:11","TRT01SDTM":"2019-07-04 15:06:11","TRT01EDTM":"2021-07-04 03:06:11","TRT02SDTM":"2021-07-04 03:06:11","TRT02EDTM":"2022-07-04 09:06:11","AP01SDTM":"2019-07-04 15:06:11","AP01EDTM":"2021-07-04 03:06:11","AP02SDTM":"2021-07-04 03:06:11","AP02EDTM":"2022-07-04 09:06:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-04","EOSDY":1096,"LSTALVDT":"2022-07-24","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3141,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.2652,"AVALU":"U/L","BASE2":42.01618,"BASE":13.7347,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-22.75097,"PCHG2":-54.14813,"CHG":5.5305,"PCHG":40.26663,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-22 15:06:11","ADY":507,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-322","SUBJID":"id-322","SITEID":"CHN-12","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.28899,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-01","TRTSDTM":"2019-07-04 15:06:11","TRTEDTM":"2022-07-04 09:06:11","TRT01SDTM":"2019-07-04 15:06:11","TRT01EDTM":"2021-07-04 03:06:11","TRT02SDTM":"2021-07-04 03:06:11","TRT02EDTM":"2022-07-04 09:06:11","AP01SDTM":"2019-07-04 15:06:11","AP01EDTM":"2021-07-04 03:06:11","AP02SDTM":"2021-07-04 03:06:11","AP02EDTM":"2022-07-04 09:06:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-04","EOSDY":1096,"LSTALVDT":"2022-07-24","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3496,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.86863,"AVALU":"U/L","BASE2":42.01618,"BASE":13.7347,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-23.14755,"PCHG2":-55.09198,"CHG":5.13393,"PCHG":37.37927,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-21 15:06:11","ADY":687,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-322","SUBJID":"id-322","SITEID":"CHN-12","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.28899,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-01","TRTSDTM":"2019-07-04 15:06:11","TRTEDTM":"2022-07-04 09:06:11","TRT01SDTM":"2019-07-04 15:06:11","TRT01EDTM":"2021-07-04 03:06:11","TRT02SDTM":"2021-07-04 03:06:11","TRT02EDTM":"2022-07-04 09:06:11","AP01SDTM":"2019-07-04 15:06:11","AP01EDTM":"2021-07-04 03:06:11","AP02SDTM":"2021-07-04 03:06:11","AP02EDTM":"2022-07-04 09:06:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-04","EOSDY":1096,"LSTALVDT":"2022-07-24","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5211,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.02538,"AVALU":"U/L","BASE2":42.01618,"BASE":13.7347,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-22.9908,"PCHG2":-54.71891,"CHG":5.29068,"PCHG":38.52053,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-29 15:06:11","ADY":787,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-322","SUBJID":"id-322","SITEID":"CHN-12","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.28899,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-01","TRTSDTM":"2019-07-04 15:06:11","TRTEDTM":"2022-07-04 09:06:11","TRT01SDTM":"2019-07-04 15:06:11","TRT01EDTM":"2021-07-04 03:06:11","TRT02SDTM":"2021-07-04 03:06:11","TRT02EDTM":"2022-07-04 09:06:11","AP01SDTM":"2019-07-04 15:06:11","AP01EDTM":"2021-07-04 03:06:11","AP02SDTM":"2021-07-04 03:06:11","AP02EDTM":"2022-07-04 09:06:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-04","EOSDY":1096,"LSTALVDT":"2022-07-24","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3824,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.03152,"AVALU":"U/L","BASE2":42.01618,"BASE":13.7347,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-22.98465,"PCHG2":-54.7043,"CHG":5.29682,"PCHG":38.56525,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-08 15:06:11","ADY":950,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-322","SUBJID":"id-322","SITEID":"CHN-12","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.28899,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-01","TRTSDTM":"2019-07-04 15:06:11","TRTEDTM":"2022-07-04 09:06:11","TRT01SDTM":"2019-07-04 15:06:11","TRT01EDTM":"2021-07-04 03:06:11","TRT02SDTM":"2021-07-04 03:06:11","TRT02EDTM":"2022-07-04 09:06:11","AP01SDTM":"2019-07-04 15:06:11","AP01EDTM":"2021-07-04 03:06:11","AP02SDTM":"2021-07-04 03:06:11","AP02EDTM":"2022-07-04 09:06:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-04","EOSDY":1096,"LSTALVDT":"2022-07-24","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1167,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.42297,"AVALU":"mg/L","BASE2":8.42297,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-27 15:06:11","ADY":85,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-322","SUBJID":"id-322","SITEID":"CHN-12","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.28899,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-01","TRTSDTM":"2019-07-04 15:06:11","TRTEDTM":"2022-07-04 09:06:11","TRT01SDTM":"2019-07-04 15:06:11","TRT01EDTM":"2021-07-04 03:06:11","TRT02SDTM":"2021-07-04 03:06:11","TRT02EDTM":"2022-07-04 09:06:11","AP01SDTM":"2019-07-04 15:06:11","AP01EDTM":"2021-07-04 03:06:11","AP02SDTM":"2021-07-04 03:06:11","AP02EDTM":"2022-07-04 09:06:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-04","EOSDY":1096,"LSTALVDT":"2022-07-24","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2302,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.29077,"AVALU":"mg/L","BASE2":8.42297,"BASE":8.29077,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.1322,"PCHG2":-1.56953,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-13 15:06:11","ADY":284,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-322","SUBJID":"id-322","SITEID":"CHN-12","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.28899,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-01","TRTSDTM":"2019-07-04 15:06:11","TRTEDTM":"2022-07-04 09:06:11","TRT01SDTM":"2019-07-04 15:06:11","TRT01EDTM":"2021-07-04 03:06:11","TRT02SDTM":"2021-07-04 03:06:11","TRT02EDTM":"2022-07-04 09:06:11","AP01SDTM":"2019-07-04 15:06:11","AP01EDTM":"2021-07-04 03:06:11","AP02SDTM":"2021-07-04 03:06:11","AP02EDTM":"2022-07-04 09:06:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-04","EOSDY":1096,"LSTALVDT":"2022-07-24","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3630,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.73909,"AVALU":"mg/L","BASE2":8.42297,"BASE":8.29077,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.31612,"PCHG2":27.49761,"CHG":2.44832,"PCHG":29.53064,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-04-25 15:06:11","ADY":296,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-322","SUBJID":"id-322","SITEID":"CHN-12","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.28899,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-01","TRTSDTM":"2019-07-04 15:06:11","TRTEDTM":"2022-07-04 09:06:11","TRT01SDTM":"2019-07-04 15:06:11","TRT01EDTM":"2021-07-04 03:06:11","TRT02SDTM":"2021-07-04 03:06:11","TRT02EDTM":"2022-07-04 09:06:11","AP01SDTM":"2019-07-04 15:06:11","AP01EDTM":"2021-07-04 03:06:11","AP02SDTM":"2021-07-04 03:06:11","AP02EDTM":"2022-07-04 09:06:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-04","EOSDY":1096,"LSTALVDT":"2022-07-24","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7802,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.62676,"AVALU":"mg/L","BASE2":8.42297,"BASE":8.29077,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.20379,"PCHG2":26.164,"CHG":2.33599,"PCHG":28.17575,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-11-22 15:06:11","ADY":507,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-322","SUBJID":"id-322","SITEID":"CHN-12","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.28899,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-01","TRTSDTM":"2019-07-04 15:06:11","TRTEDTM":"2022-07-04 09:06:11","TRT01SDTM":"2019-07-04 15:06:11","TRT01EDTM":"2021-07-04 03:06:11","TRT02SDTM":"2021-07-04 03:06:11","TRT02EDTM":"2022-07-04 09:06:11","AP01SDTM":"2019-07-04 15:06:11","AP01EDTM":"2021-07-04 03:06:11","AP02SDTM":"2021-07-04 03:06:11","AP02EDTM":"2022-07-04 09:06:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-04","EOSDY":1096,"LSTALVDT":"2022-07-24","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":593,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.21994,"AVALU":"mg/L","BASE2":8.42297,"BASE":8.29077,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.79697,"PCHG2":21.33413,"CHG":1.92917,"PCHG":23.26888,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-05-21 15:06:11","ADY":687,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-322","SUBJID":"id-322","SITEID":"CHN-12","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.28899,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-01","TRTSDTM":"2019-07-04 15:06:11","TRTEDTM":"2022-07-04 09:06:11","TRT01SDTM":"2019-07-04 15:06:11","TRT01EDTM":"2021-07-04 03:06:11","TRT02SDTM":"2021-07-04 03:06:11","TRT02EDTM":"2022-07-04 09:06:11","AP01SDTM":"2019-07-04 15:06:11","AP01EDTM":"2021-07-04 03:06:11","AP02SDTM":"2021-07-04 03:06:11","AP02EDTM":"2022-07-04 09:06:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-04","EOSDY":1096,"LSTALVDT":"2022-07-24","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3183,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.91803,"AVALU":"mg/L","BASE2":8.42297,"BASE":8.29077,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.50494,"PCHG2":-5.99485,"CHG":-0.37274,"PCHG":-4.49588,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-08-29 15:06:11","ADY":787,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-322","SUBJID":"id-322","SITEID":"CHN-12","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.28899,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-01","TRTSDTM":"2019-07-04 15:06:11","TRTEDTM":"2022-07-04 09:06:11","TRT01SDTM":"2019-07-04 15:06:11","TRT01EDTM":"2021-07-04 03:06:11","TRT02SDTM":"2021-07-04 03:06:11","TRT02EDTM":"2022-07-04 09:06:11","AP01SDTM":"2019-07-04 15:06:11","AP01EDTM":"2021-07-04 03:06:11","AP02SDTM":"2021-07-04 03:06:11","AP02EDTM":"2022-07-04 09:06:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-04","EOSDY":1096,"LSTALVDT":"2022-07-24","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5575,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.48315,"AVALU":"mg/L","BASE2":8.42297,"BASE":8.29077,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.06018,"PCHG2":12.58677,"CHG":1.19238,"PCHG":14.38204,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-08 15:06:11","ADY":950,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-322","SUBJID":"id-322","SITEID":"CHN-12","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.28899,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-01","TRTSDTM":"2019-07-04 15:06:11","TRTEDTM":"2022-07-04 09:06:11","TRT01SDTM":"2019-07-04 15:06:11","TRT01EDTM":"2021-07-04 03:06:11","TRT02SDTM":"2021-07-04 03:06:11","TRT02EDTM":"2022-07-04 09:06:11","AP01SDTM":"2019-07-04 15:06:11","AP01EDTM":"2021-07-04 03:06:11","AP02SDTM":"2021-07-04 03:06:11","AP02EDTM":"2022-07-04 09:06:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-04","EOSDY":1096,"LSTALVDT":"2022-07-24","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4036,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9551,"AVALU":"g/L","BASE2":2.9551,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-27 15:06:11","ADY":85,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-322","SUBJID":"id-322","SITEID":"CHN-12","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.28899,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-01","TRTSDTM":"2019-07-04 15:06:11","TRTEDTM":"2022-07-04 09:06:11","TRT01SDTM":"2019-07-04 15:06:11","TRT01EDTM":"2021-07-04 03:06:11","TRT02SDTM":"2021-07-04 03:06:11","TRT02EDTM":"2022-07-04 09:06:11","AP01SDTM":"2019-07-04 15:06:11","AP01EDTM":"2021-07-04 03:06:11","AP02SDTM":"2021-07-04 03:06:11","AP02EDTM":"2022-07-04 09:06:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-04","EOSDY":1096,"LSTALVDT":"2022-07-24","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4181,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9979,"AVALU":"g/L","BASE2":2.9551,"BASE":2.9979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.0428,"PCHG2":1.44823,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-13 15:06:11","ADY":284,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-322","SUBJID":"id-322","SITEID":"CHN-12","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.28899,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-01","TRTSDTM":"2019-07-04 15:06:11","TRTEDTM":"2022-07-04 09:06:11","TRT01SDTM":"2019-07-04 15:06:11","TRT01EDTM":"2021-07-04 03:06:11","TRT02SDTM":"2021-07-04 03:06:11","TRT02EDTM":"2022-07-04 09:06:11","AP01SDTM":"2019-07-04 15:06:11","AP01EDTM":"2021-07-04 03:06:11","AP02SDTM":"2021-07-04 03:06:11","AP02EDTM":"2022-07-04 09:06:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-04","EOSDY":1096,"LSTALVDT":"2022-07-24","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1630,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86333,"AVALU":"g/L","BASE2":2.9551,"BASE":2.9979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09177,"PCHG2":-3.10558,"CHG":-0.13457,"PCHG":-4.48881,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-25 15:06:11","ADY":296,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-322","SUBJID":"id-322","SITEID":"CHN-12","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.28899,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-01","TRTSDTM":"2019-07-04 15:06:11","TRTEDTM":"2022-07-04 09:06:11","TRT01SDTM":"2019-07-04 15:06:11","TRT01EDTM":"2021-07-04 03:06:11","TRT02SDTM":"2021-07-04 03:06:11","TRT02EDTM":"2022-07-04 09:06:11","AP01SDTM":"2019-07-04 15:06:11","AP01EDTM":"2021-07-04 03:06:11","AP02SDTM":"2021-07-04 03:06:11","AP02EDTM":"2022-07-04 09:06:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-04","EOSDY":1096,"LSTALVDT":"2022-07-24","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4344,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86443,"AVALU":"g/L","BASE2":2.9551,"BASE":2.9979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09068,"PCHG2":-3.06848,"CHG":-0.13347,"PCHG":-4.45224,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-22 15:06:11","ADY":507,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-322","SUBJID":"id-322","SITEID":"CHN-12","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.28899,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-01","TRTSDTM":"2019-07-04 15:06:11","TRTEDTM":"2022-07-04 09:06:11","TRT01SDTM":"2019-07-04 15:06:11","TRT01EDTM":"2021-07-04 03:06:11","TRT02SDTM":"2021-07-04 03:06:11","TRT02EDTM":"2022-07-04 09:06:11","AP01SDTM":"2019-07-04 15:06:11","AP01EDTM":"2021-07-04 03:06:11","AP02SDTM":"2021-07-04 03:06:11","AP02EDTM":"2022-07-04 09:06:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-04","EOSDY":1096,"LSTALVDT":"2022-07-24","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7814,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96114,"AVALU":"g/L","BASE2":2.9551,"BASE":2.9979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00604,"PCHG2":0.20433,"CHG":-0.03676,"PCHG":-1.22615,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-21 15:06:11","ADY":687,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-322","SUBJID":"id-322","SITEID":"CHN-12","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.28899,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-01","TRTSDTM":"2019-07-04 15:06:11","TRTEDTM":"2022-07-04 09:06:11","TRT01SDTM":"2019-07-04 15:06:11","TRT01EDTM":"2021-07-04 03:06:11","TRT02SDTM":"2021-07-04 03:06:11","TRT02EDTM":"2022-07-04 09:06:11","AP01SDTM":"2019-07-04 15:06:11","AP01EDTM":"2021-07-04 03:06:11","AP02SDTM":"2021-07-04 03:06:11","AP02EDTM":"2022-07-04 09:06:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-04","EOSDY":1096,"LSTALVDT":"2022-07-24","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2646,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78242,"AVALU":"g/L","BASE2":2.9551,"BASE":2.9979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17268,"PCHG2":-5.84357,"CHG":-0.21548,"PCHG":-7.18771,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-29 15:06:11","ADY":787,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-322","SUBJID":"id-322","SITEID":"CHN-12","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.28899,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-01","TRTSDTM":"2019-07-04 15:06:11","TRTEDTM":"2022-07-04 09:06:11","TRT01SDTM":"2019-07-04 15:06:11","TRT01EDTM":"2021-07-04 03:06:11","TRT02SDTM":"2021-07-04 03:06:11","TRT02EDTM":"2022-07-04 09:06:11","AP01SDTM":"2019-07-04 15:06:11","AP01EDTM":"2021-07-04 03:06:11","AP02SDTM":"2021-07-04 03:06:11","AP02EDTM":"2022-07-04 09:06:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-04","EOSDY":1096,"LSTALVDT":"2022-07-24","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5011,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85825,"AVALU":"g/L","BASE2":2.9551,"BASE":2.9979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09685,"PCHG2":-3.27747,"CHG":-0.13965,"PCHG":-4.65824,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-08 15:06:11","ADY":950,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-396","SUBJID":"id-396","SITEID":"CHN-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15746,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-19","TRTSDTM":"2019-09-20 10:35:35","TRT01SDTM":"2019-09-20 10:35:35","AP01SDTM":"2019-09-20 10:35:35","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6755,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.58029,"AVALU":"U/L","BASE2":19.58029,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2019-11-25 10:35:35","ADY":66,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-396","SUBJID":"id-396","SITEID":"CHN-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15746,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-19","TRTSDTM":"2019-09-20 10:35:35","TRT01SDTM":"2019-09-20 10:35:35","AP01SDTM":"2019-09-20 10:35:35","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5707,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.94425,"AVALU":"U/L","BASE2":19.58029,"BASE":5.94425,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-13.63604,"PCHG2":-69.64167,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2020-08-13 10:35:35","ADY":328,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-396","SUBJID":"id-396","SITEID":"CHN-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15746,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-19","TRTSDTM":"2019-09-20 10:35:35","TRT01SDTM":"2019-09-20 10:35:35","AP01SDTM":"2019-09-20 10:35:35","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4244,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.27417,"AVALU":"U/L","BASE2":19.58029,"BASE":5.94425,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.69388,"PCHG2":44.4012,"CHG":22.32992,"PCHG":375.65598,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-10-22 10:35:35","ADY":398,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-396","SUBJID":"id-396","SITEID":"CHN-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15746,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-19","TRTSDTM":"2019-09-20 10:35:35","TRT01SDTM":"2019-09-20 10:35:35","AP01SDTM":"2019-09-20 10:35:35","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2030,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.60652,"AVALU":"U/L","BASE2":19.58029,"BASE":5.94425,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.97376,"PCHG2":-40.72343,"CHG":5.66228,"PCHG":95.25638,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-12-07 10:35:35","ADY":444,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-396","SUBJID":"id-396","SITEID":"CHN-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15746,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-19","TRTSDTM":"2019-09-20 10:35:35","TRT01SDTM":"2019-09-20 10:35:35","AP01SDTM":"2019-09-20 10:35:35","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4597,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.01622,"AVALU":"U/L","BASE2":19.58029,"BASE":5.94425,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.56407,"PCHG2":-13.09517,"CHG":11.07197,"PCHG":186.26356,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-12-22 10:35:35","ADY":459,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-396","SUBJID":"id-396","SITEID":"CHN-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15746,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-19","TRTSDTM":"2019-09-20 10:35:35","TRT01SDTM":"2019-09-20 10:35:35","AP01SDTM":"2019-09-20 10:35:35","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1591,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.20627,"AVALU":"U/L","BASE2":19.58029,"BASE":5.94425,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.37402,"PCHG2":-12.12453,"CHG":11.26202,"PCHG":189.46086,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-03-05 10:35:35","ADY":532,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-396","SUBJID":"id-396","SITEID":"CHN-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15746,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-19","TRTSDTM":"2019-09-20 10:35:35","TRT01SDTM":"2019-09-20 10:35:35","AP01SDTM":"2019-09-20 10:35:35","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":466,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.73597,"AVALU":"U/L","BASE2":19.58029,"BASE":5.94425,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.84432,"PCHG2":-29.84797,"CHG":7.79172,"PCHG":131.08001,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-03-21 10:35:35","ADY":548,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-396","SUBJID":"id-396","SITEID":"CHN-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15746,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-19","TRTSDTM":"2019-09-20 10:35:35","TRT01SDTM":"2019-09-20 10:35:35","AP01SDTM":"2019-09-20 10:35:35","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3089,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.06353,"AVALU":"mg/L","BASE2":8.06353,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-25 10:35:35","ADY":66,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-396","SUBJID":"id-396","SITEID":"CHN-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15746,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-19","TRTSDTM":"2019-09-20 10:35:35","TRT01SDTM":"2019-09-20 10:35:35","AP01SDTM":"2019-09-20 10:35:35","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3899,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.68843,"AVALU":"mg/L","BASE2":8.06353,"BASE":8.68843,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.62489,"PCHG2":7.74962,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-13 10:35:35","ADY":328,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-396","SUBJID":"id-396","SITEID":"CHN-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15746,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-19","TRTSDTM":"2019-09-20 10:35:35","TRT01SDTM":"2019-09-20 10:35:35","AP01SDTM":"2019-09-20 10:35:35","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":484,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.85634,"AVALU":"mg/L","BASE2":8.06353,"BASE":8.68843,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20719,"PCHG2":-2.56953,"CHG":-0.83209,"PCHG":-9.57697,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-10-22 10:35:35","ADY":398,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-396","SUBJID":"id-396","SITEID":"CHN-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15746,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-19","TRTSDTM":"2019-09-20 10:35:35","TRT01SDTM":"2019-09-20 10:35:35","AP01SDTM":"2019-09-20 10:35:35","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":207,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.94053,"AVALU":"mg/L","BASE2":8.06353,"BASE":8.68843,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.877,"PCHG2":23.27762,"CHG":1.2521,"PCHG":14.41118,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-07 10:35:35","ADY":444,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-396","SUBJID":"id-396","SITEID":"CHN-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15746,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-19","TRTSDTM":"2019-09-20 10:35:35","TRT01SDTM":"2019-09-20 10:35:35","AP01SDTM":"2019-09-20 10:35:35","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7996,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.5041,"AVALU":"mg/L","BASE2":8.06353,"BASE":8.68843,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.44057,"PCHG2":5.46368,"CHG":-0.18433,"PCHG":-2.12153,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-22 10:35:35","ADY":459,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-396","SUBJID":"id-396","SITEID":"CHN-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15746,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-19","TRTSDTM":"2019-09-20 10:35:35","TRT01SDTM":"2019-09-20 10:35:35","AP01SDTM":"2019-09-20 10:35:35","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4605,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.44556,"AVALU":"mg/L","BASE2":8.06353,"BASE":8.68843,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.38203,"PCHG2":17.13925,"CHG":0.75714,"PCHG":8.7143,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-05 10:35:35","ADY":532,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-396","SUBJID":"id-396","SITEID":"CHN-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15746,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-19","TRTSDTM":"2019-09-20 10:35:35","TRT01SDTM":"2019-09-20 10:35:35","AP01SDTM":"2019-09-20 10:35:35","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1065,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.06187,"AVALU":"mg/L","BASE2":8.06353,"BASE":8.68843,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.99834,"PCHG2":12.38087,"CHG":0.37344,"PCHG":4.29816,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-21 10:35:35","ADY":548,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-396","SUBJID":"id-396","SITEID":"CHN-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15746,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-19","TRTSDTM":"2019-09-20 10:35:35","TRT01SDTM":"2019-09-20 10:35:35","AP01SDTM":"2019-09-20 10:35:35","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7944,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9271,"AVALU":"g/L","BASE2":2.9271,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-25 10:35:35","ADY":66,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-396","SUBJID":"id-396","SITEID":"CHN-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15746,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-19","TRTSDTM":"2019-09-20 10:35:35","TRT01SDTM":"2019-09-20 10:35:35","AP01SDTM":"2019-09-20 10:35:35","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7838,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78708,"AVALU":"g/L","BASE2":2.9271,"BASE":2.78708,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.14002,"PCHG2":-4.78355,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-13 10:35:35","ADY":328,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-396","SUBJID":"id-396","SITEID":"CHN-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15746,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-19","TRTSDTM":"2019-09-20 10:35:35","TRT01SDTM":"2019-09-20 10:35:35","AP01SDTM":"2019-09-20 10:35:35","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":846,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00642,"AVALU":"g/L","BASE2":2.9271,"BASE":2.78708,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07933,"PCHG2":2.71004,"CHG":0.21934,"PCHG":7.87005,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-10-22 10:35:35","ADY":398,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-396","SUBJID":"id-396","SITEID":"CHN-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15746,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-19","TRTSDTM":"2019-09-20 10:35:35","TRT01SDTM":"2019-09-20 10:35:35","AP01SDTM":"2019-09-20 10:35:35","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5343,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79598,"AVALU":"g/L","BASE2":2.9271,"BASE":2.78708,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13112,"PCHG2":-4.47944,"CHG":0.0089,"PCHG":0.31939,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-07 10:35:35","ADY":444,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-396","SUBJID":"id-396","SITEID":"CHN-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15746,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-19","TRTSDTM":"2019-09-20 10:35:35","TRT01SDTM":"2019-09-20 10:35:35","AP01SDTM":"2019-09-20 10:35:35","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2267,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9995,"AVALU":"g/L","BASE2":2.9271,"BASE":2.78708,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07241,"PCHG2":2.4737,"CHG":0.21243,"PCHG":7.62184,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-22 10:35:35","ADY":459,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-396","SUBJID":"id-396","SITEID":"CHN-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15746,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-19","TRTSDTM":"2019-09-20 10:35:35","TRT01SDTM":"2019-09-20 10:35:35","AP01SDTM":"2019-09-20 10:35:35","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2632,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00994,"AVALU":"g/L","BASE2":2.9271,"BASE":2.78708,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08284,"PCHG2":2.8302,"CHG":0.22286,"PCHG":7.99625,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-03-05 10:35:35","ADY":532,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-396","SUBJID":"id-396","SITEID":"CHN-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.15746,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-19","TRTSDTM":"2019-09-20 10:35:35","TRT01SDTM":"2019-09-20 10:35:35","AP01SDTM":"2019-09-20 10:35:35","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":282,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97323,"AVALU":"g/L","BASE2":2.9271,"BASE":2.78708,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04613,"PCHG2":1.57601,"CHG":0.18615,"PCHG":6.67905,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-21 10:35:35","ADY":548,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-57","SUBJID":"id-57","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.92748,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 01:09:21","TRT01SDTM":"2019-10-13 01:09:21","AP01SDTM":"2019-10-13 01:09:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7862,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.2267,"AVALU":"U/L","BASE2":16.2267,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-19 01:09:21","ADY":37,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-57","SUBJID":"id-57","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.92748,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 01:09:21","TRT01SDTM":"2019-10-13 01:09:21","AP01SDTM":"2019-10-13 01:09:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2047,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.86769,"AVALU":"U/L","BASE2":16.2267,"BASE":28.86769,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":12.64099,"PCHG2":77.90245,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-05 01:09:21","ADY":115,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-57","SUBJID":"id-57","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.92748,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 01:09:21","TRT01SDTM":"2019-10-13 01:09:21","AP01SDTM":"2019-10-13 01:09:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6884,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.24706,"AVALU":"U/L","BASE2":16.2267,"BASE":28.86769,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02037,"PCHG2":0.12551,"CHG":-12.62063,"PCHG":-43.71887,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-03 01:09:21","ADY":234,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-57","SUBJID":"id-57","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.92748,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 01:09:21","TRT01SDTM":"2019-10-13 01:09:21","AP01SDTM":"2019-10-13 01:09:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":922,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.58879,"AVALU":"U/L","BASE2":16.2267,"BASE":28.86769,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.63791,"PCHG2":-34.74463,"CHG":-18.2789,"PCHG":-63.31958,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-08 01:09:21","ADY":239,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-57","SUBJID":"id-57","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.92748,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 01:09:21","TRT01SDTM":"2019-10-13 01:09:21","AP01SDTM":"2019-10-13 01:09:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4118,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.25813,"AVALU":"U/L","BASE2":16.2267,"BASE":28.86769,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.03143,"PCHG2":80.30859,"CHG":0.39044,"PCHG":1.35251,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-24 01:09:21","ADY":255,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-57","SUBJID":"id-57","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.92748,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 01:09:21","TRT01SDTM":"2019-10-13 01:09:21","AP01SDTM":"2019-10-13 01:09:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2022,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":43.86057,"AVALU":"U/L","BASE2":16.2267,"BASE":28.86769,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":27.63388,"PCHG2":170.29885,"CHG":14.99288,"PCHG":51.93656,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-13 01:09:21","ADY":305,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-57","SUBJID":"id-57","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.92748,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 01:09:21","TRT01SDTM":"2019-10-13 01:09:21","AP01SDTM":"2019-10-13 01:09:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7527,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":41.29436,"AVALU":"U/L","BASE2":16.2267,"BASE":28.86769,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":25.06766,"PCHG2":154.4841,"CHG":12.42667,"PCHG":43.04699,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-22 01:09:21","ADY":710,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-57","SUBJID":"id-57","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.92748,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 01:09:21","TRT01SDTM":"2019-10-13 01:09:21","AP01SDTM":"2019-10-13 01:09:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1914,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.42492,"AVALU":"mg/L","BASE2":10.42492,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"3","ADTM":"2019-11-19 01:09:21","ADY":37,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-57","SUBJID":"id-57","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.92748,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 01:09:21","TRT01SDTM":"2019-10-13 01:09:21","AP01SDTM":"2019-10-13 01:09:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8045,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.18483,"AVALU":"mg/L","BASE2":10.42492,"BASE":10.18483,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.24009,"PCHG2":-2.30308,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2020-02-05 01:09:21","ADY":115,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-57","SUBJID":"id-57","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.92748,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 01:09:21","TRT01SDTM":"2019-10-13 01:09:21","AP01SDTM":"2019-10-13 01:09:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4315,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.55519,"AVALU":"mg/L","BASE2":10.42492,"BASE":10.18483,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.86973,"PCHG2":-8.34283,"CHG":-0.62964,"PCHG":-6.18213,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-06-03 01:09:21","ADY":234,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-57","SUBJID":"id-57","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.92748,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 01:09:21","TRT01SDTM":"2019-10-13 01:09:21","AP01SDTM":"2019-10-13 01:09:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5792,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.16311,"AVALU":"mg/L","BASE2":10.42492,"BASE":10.18483,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.26181,"PCHG2":-2.51135,"CHG":-0.02171,"PCHG":-0.21318,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"1","BTOXGR":"3","ADTM":"2020-06-08 01:09:21","ADY":239,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-57","SUBJID":"id-57","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.92748,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 01:09:21","TRT01SDTM":"2019-10-13 01:09:21","AP01SDTM":"2019-10-13 01:09:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":956,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.98261,"AVALU":"mg/L","BASE2":10.42492,"BASE":10.18483,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.44231,"PCHG2":-23.42764,"CHG":-2.20222,"PCHG":-21.62255,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-1","BTOXGR":"3","ADTM":"2020-06-24 01:09:21","ADY":255,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-57","SUBJID":"id-57","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.92748,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 01:09:21","TRT01SDTM":"2019-10-13 01:09:21","AP01SDTM":"2019-10-13 01:09:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8205,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.84629,"AVALU":"mg/L","BASE2":10.42492,"BASE":10.18483,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.57863,"PCHG2":-15.14286,"CHG":-1.33854,"PCHG":-13.14246,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-08-13 01:09:21","ADY":305,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-57","SUBJID":"id-57","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.92748,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 01:09:21","TRT01SDTM":"2019-10-13 01:09:21","AP01SDTM":"2019-10-13 01:09:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2265,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.38692,"AVALU":"mg/L","BASE2":10.42492,"BASE":10.18483,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.03801,"PCHG2":-29.14176,"CHG":-2.79791,"PCHG":-27.47137,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-3","BTOXGR":"3","ADTM":"2021-09-22 01:09:21","ADY":710,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-57","SUBJID":"id-57","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.92748,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 01:09:21","TRT01SDTM":"2019-10-13 01:09:21","AP01SDTM":"2019-10-13 01:09:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6596,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9088,"AVALU":"g/L","BASE2":2.9088,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-19 01:09:21","ADY":37,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-57","SUBJID":"id-57","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.92748,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 01:09:21","TRT01SDTM":"2019-10-13 01:09:21","AP01SDTM":"2019-10-13 01:09:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4371,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9103,"AVALU":"g/L","BASE2":2.9088,"BASE":2.9103,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.0015,"PCHG2":0.05164,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-05 01:09:21","ADY":115,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-57","SUBJID":"id-57","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.92748,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 01:09:21","TRT01SDTM":"2019-10-13 01:09:21","AP01SDTM":"2019-10-13 01:09:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4921,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92058,"AVALU":"g/L","BASE2":2.9088,"BASE":2.9103,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01179,"PCHG2":0.40517,"CHG":0.01028,"PCHG":0.35335,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-03 01:09:21","ADY":234,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-57","SUBJID":"id-57","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.92748,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 01:09:21","TRT01SDTM":"2019-10-13 01:09:21","AP01SDTM":"2019-10-13 01:09:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3193,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90086,"AVALU":"g/L","BASE2":2.9088,"BASE":2.9103,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00794,"PCHG2":-0.27298,"CHG":-0.00944,"PCHG":-0.32446,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-08 01:09:21","ADY":239,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-57","SUBJID":"id-57","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.92748,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 01:09:21","TRT01SDTM":"2019-10-13 01:09:21","AP01SDTM":"2019-10-13 01:09:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3765,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91145,"AVALU":"g/L","BASE2":2.9088,"BASE":2.9103,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00265,"PCHG2":0.09123,"CHG":0.00115,"PCHG":0.03957,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-24 01:09:21","ADY":255,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-57","SUBJID":"id-57","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.92748,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 01:09:21","TRT01SDTM":"2019-10-13 01:09:21","AP01SDTM":"2019-10-13 01:09:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2629,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90823,"AVALU":"g/L","BASE2":2.9088,"BASE":2.9103,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00057,"PCHG2":-0.01963,"CHG":-0.00207,"PCHG":-0.07123,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-13 01:09:21","ADY":305,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-12-id-57","SUBJID":"id-57","SITEID":"CHN-12","AGE":45,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-12","INVNAM":"Dr. CHN-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.92748,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 01:09:21","TRT01SDTM":"2019-10-13 01:09:21","AP01SDTM":"2019-10-13 01:09:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4141,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78212,"AVALU":"g/L","BASE2":2.9088,"BASE":2.9103,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12668,"PCHG2":-4.35494,"CHG":-0.12818,"PCHG":-4.4043,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-22 01:09:21","ADY":710,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-102","SUBJID":"id-102","SITEID":"CHN-13","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.04895,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-23","TRTSDTM":"2019-03-23 06:06:17","TRTEDTM":"2022-03-23 00:06:17","TRT01SDTM":"2019-03-23 06:06:17","TRT01EDTM":"2021-03-22 18:06:17","TRT02SDTM":"2021-03-22 18:06:17","TRT02EDTM":"2022-03-23 00:06:17","AP01SDTM":"2019-03-23 06:06:17","AP01EDTM":"2021-03-22 18:06:17","AP02SDTM":"2021-03-22 18:06:17","AP02EDTM":"2022-03-23 00:06:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-23","EOSDY":1096,"LSTALVDT":"2022-04-12","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5648,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.24931,"AVALU":"U/L","BASE2":29.24931,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-06 06:06:17","ADY":105,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-102","SUBJID":"id-102","SITEID":"CHN-13","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.04895,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-23","TRTSDTM":"2019-03-23 06:06:17","TRTEDTM":"2022-03-23 00:06:17","TRT01SDTM":"2019-03-23 06:06:17","TRT01EDTM":"2021-03-22 18:06:17","TRT02SDTM":"2021-03-22 18:06:17","TRT02EDTM":"2022-03-23 00:06:17","AP01SDTM":"2019-03-23 06:06:17","AP01EDTM":"2021-03-22 18:06:17","AP02SDTM":"2021-03-22 18:06:17","AP02EDTM":"2022-03-23 00:06:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-23","EOSDY":1096,"LSTALVDT":"2022-04-12","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7984,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.65144,"AVALU":"U/L","BASE2":29.24931,"BASE":30.65144,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.40213,"PCHG2":4.79373,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-07 06:06:17","ADY":137,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-102","SUBJID":"id-102","SITEID":"CHN-13","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.04895,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-23","TRTSDTM":"2019-03-23 06:06:17","TRTEDTM":"2022-03-23 00:06:17","TRT01SDTM":"2019-03-23 06:06:17","TRT01EDTM":"2021-03-22 18:06:17","TRT02SDTM":"2021-03-22 18:06:17","TRT02EDTM":"2022-03-23 00:06:17","AP01SDTM":"2019-03-23 06:06:17","AP01EDTM":"2021-03-22 18:06:17","AP02SDTM":"2021-03-22 18:06:17","AP02EDTM":"2022-03-23 00:06:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-23","EOSDY":1096,"LSTALVDT":"2022-04-12","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7634,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.27319,"AVALU":"U/L","BASE2":29.24931,"BASE":30.65144,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.97612,"PCHG2":-37.52609,"CHG":-12.37825,"PCHG":-40.38392,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-23 06:06:17","ADY":427,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-102","SUBJID":"id-102","SITEID":"CHN-13","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.04895,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-23","TRTSDTM":"2019-03-23 06:06:17","TRTEDTM":"2022-03-23 00:06:17","TRT01SDTM":"2019-03-23 06:06:17","TRT01EDTM":"2021-03-22 18:06:17","TRT02SDTM":"2021-03-22 18:06:17","TRT02EDTM":"2022-03-23 00:06:17","AP01SDTM":"2019-03-23 06:06:17","AP01EDTM":"2021-03-22 18:06:17","AP02SDTM":"2021-03-22 18:06:17","AP02EDTM":"2022-03-23 00:06:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-23","EOSDY":1096,"LSTALVDT":"2022-04-12","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":873,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":42.83654,"AVALU":"U/L","BASE2":29.24931,"BASE":30.65144,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.58723,"PCHG2":46.45317,"CHG":12.1851,"PCHG":39.75376,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-16 06:06:17","ADY":451,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-102","SUBJID":"id-102","SITEID":"CHN-13","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.04895,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-23","TRTSDTM":"2019-03-23 06:06:17","TRTEDTM":"2022-03-23 00:06:17","TRT01SDTM":"2019-03-23 06:06:17","TRT01EDTM":"2021-03-22 18:06:17","TRT02SDTM":"2021-03-22 18:06:17","TRT02EDTM":"2022-03-23 00:06:17","AP01SDTM":"2019-03-23 06:06:17","AP01EDTM":"2021-03-22 18:06:17","AP02SDTM":"2021-03-22 18:06:17","AP02EDTM":"2022-03-23 00:06:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-23","EOSDY":1096,"LSTALVDT":"2022-04-12","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7036,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.00809,"AVALU":"U/L","BASE2":29.24931,"BASE":30.65144,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.24122,"PCHG2":-28.17578,"CHG":-9.64335,"PCHG":-31.46134,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-28 06:06:17","ADY":493,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-102","SUBJID":"id-102","SITEID":"CHN-13","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.04895,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-23","TRTSDTM":"2019-03-23 06:06:17","TRTEDTM":"2022-03-23 00:06:17","TRT01SDTM":"2019-03-23 06:06:17","TRT01EDTM":"2021-03-22 18:06:17","TRT02SDTM":"2021-03-22 18:06:17","TRT02EDTM":"2022-03-23 00:06:17","AP01SDTM":"2019-03-23 06:06:17","AP01EDTM":"2021-03-22 18:06:17","AP02SDTM":"2021-03-22 18:06:17","AP02EDTM":"2022-03-23 00:06:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-23","EOSDY":1096,"LSTALVDT":"2022-04-12","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7267,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.74835,"AVALU":"U/L","BASE2":29.24931,"BASE":30.65144,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.50096,"PCHG2":-29.0638,"CHG":-9.90309,"PCHG":-32.30874,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-10 06:06:17","ADY":902,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-102","SUBJID":"id-102","SITEID":"CHN-13","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.04895,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-23","TRTSDTM":"2019-03-23 06:06:17","TRTEDTM":"2022-03-23 00:06:17","TRT01SDTM":"2019-03-23 06:06:17","TRT01EDTM":"2021-03-22 18:06:17","TRT02SDTM":"2021-03-22 18:06:17","TRT02EDTM":"2022-03-23 00:06:17","AP01SDTM":"2019-03-23 06:06:17","AP01EDTM":"2021-03-22 18:06:17","AP02SDTM":"2021-03-22 18:06:17","AP02EDTM":"2022-03-23 00:06:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-23","EOSDY":1096,"LSTALVDT":"2022-04-12","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6889,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.90366,"AVALU":"U/L","BASE2":29.24931,"BASE":30.65144,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.65435,"PCHG2":5.65604,"CHG":0.25222,"PCHG":0.82287,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-09 06:06:17","ADY":992,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-102","SUBJID":"id-102","SITEID":"CHN-13","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.04895,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-23","TRTSDTM":"2019-03-23 06:06:17","TRTEDTM":"2022-03-23 00:06:17","TRT01SDTM":"2019-03-23 06:06:17","TRT01EDTM":"2021-03-22 18:06:17","TRT02SDTM":"2021-03-22 18:06:17","TRT02EDTM":"2022-03-23 00:06:17","AP01SDTM":"2019-03-23 06:06:17","AP01EDTM":"2021-03-22 18:06:17","AP02SDTM":"2021-03-22 18:06:17","AP02EDTM":"2022-03-23 00:06:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-23","EOSDY":1096,"LSTALVDT":"2022-04-12","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4599,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.2646,"AVALU":"mg/L","BASE2":9.2646,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-06 06:06:17","ADY":105,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-102","SUBJID":"id-102","SITEID":"CHN-13","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.04895,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-23","TRTSDTM":"2019-03-23 06:06:17","TRTEDTM":"2022-03-23 00:06:17","TRT01SDTM":"2019-03-23 06:06:17","TRT01EDTM":"2021-03-22 18:06:17","TRT02SDTM":"2021-03-22 18:06:17","TRT02EDTM":"2022-03-23 00:06:17","AP01SDTM":"2019-03-23 06:06:17","AP01EDTM":"2021-03-22 18:06:17","AP02SDTM":"2021-03-22 18:06:17","AP02EDTM":"2022-03-23 00:06:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-23","EOSDY":1096,"LSTALVDT":"2022-04-12","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6214,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.73143,"AVALU":"mg/L","BASE2":9.2646,"BASE":8.73143,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.53316,"PCHG2":-5.75485,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-07 06:06:17","ADY":137,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-102","SUBJID":"id-102","SITEID":"CHN-13","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.04895,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-23","TRTSDTM":"2019-03-23 06:06:17","TRTEDTM":"2022-03-23 00:06:17","TRT01SDTM":"2019-03-23 06:06:17","TRT01EDTM":"2021-03-22 18:06:17","TRT02SDTM":"2021-03-22 18:06:17","TRT02EDTM":"2022-03-23 00:06:17","AP01SDTM":"2019-03-23 06:06:17","AP01EDTM":"2021-03-22 18:06:17","AP02SDTM":"2021-03-22 18:06:17","AP02EDTM":"2022-03-23 00:06:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-23","EOSDY":1096,"LSTALVDT":"2022-04-12","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5687,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.26224,"AVALU":"mg/L","BASE2":9.2646,"BASE":8.73143,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.00236,"PCHG2":-10.81922,"CHG":-0.46919,"PCHG":-5.37361,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-23 06:06:17","ADY":427,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-102","SUBJID":"id-102","SITEID":"CHN-13","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.04895,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-23","TRTSDTM":"2019-03-23 06:06:17","TRTEDTM":"2022-03-23 00:06:17","TRT01SDTM":"2019-03-23 06:06:17","TRT01EDTM":"2021-03-22 18:06:17","TRT02SDTM":"2021-03-22 18:06:17","TRT02EDTM":"2022-03-23 00:06:17","AP01SDTM":"2019-03-23 06:06:17","AP01EDTM":"2021-03-22 18:06:17","AP02SDTM":"2021-03-22 18:06:17","AP02EDTM":"2022-03-23 00:06:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-23","EOSDY":1096,"LSTALVDT":"2022-04-12","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":376,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.32664,"AVALU":"mg/L","BASE2":9.2646,"BASE":8.73143,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06204,"PCHG2":0.66962,"CHG":0.5952,"PCHG":6.81677,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-16 06:06:17","ADY":451,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-102","SUBJID":"id-102","SITEID":"CHN-13","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.04895,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-23","TRTSDTM":"2019-03-23 06:06:17","TRTEDTM":"2022-03-23 00:06:17","TRT01SDTM":"2019-03-23 06:06:17","TRT01EDTM":"2021-03-22 18:06:17","TRT02SDTM":"2021-03-22 18:06:17","TRT02EDTM":"2022-03-23 00:06:17","AP01SDTM":"2019-03-23 06:06:17","AP01EDTM":"2021-03-22 18:06:17","AP02SDTM":"2021-03-22 18:06:17","AP02EDTM":"2022-03-23 00:06:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-23","EOSDY":1096,"LSTALVDT":"2022-04-12","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1138,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.6522,"AVALU":"mg/L","BASE2":9.2646,"BASE":8.73143,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.6124,"PCHG2":-6.61014,"CHG":-0.07924,"PCHG":-0.90751,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-28 06:06:17","ADY":493,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-102","SUBJID":"id-102","SITEID":"CHN-13","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.04895,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-23","TRTSDTM":"2019-03-23 06:06:17","TRTEDTM":"2022-03-23 00:06:17","TRT01SDTM":"2019-03-23 06:06:17","TRT01EDTM":"2021-03-22 18:06:17","TRT02SDTM":"2021-03-22 18:06:17","TRT02EDTM":"2022-03-23 00:06:17","AP01SDTM":"2019-03-23 06:06:17","AP01EDTM":"2021-03-22 18:06:17","AP02SDTM":"2021-03-22 18:06:17","AP02EDTM":"2022-03-23 00:06:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-23","EOSDY":1096,"LSTALVDT":"2022-04-12","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8279,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.52574,"AVALU":"mg/L","BASE2":9.2646,"BASE":8.73143,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.26115,"PCHG2":2.81875,"CHG":0.79431,"PCHG":9.09712,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-10 06:06:17","ADY":902,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-102","SUBJID":"id-102","SITEID":"CHN-13","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.04895,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-23","TRTSDTM":"2019-03-23 06:06:17","TRTEDTM":"2022-03-23 00:06:17","TRT01SDTM":"2019-03-23 06:06:17","TRT01EDTM":"2021-03-22 18:06:17","TRT02SDTM":"2021-03-22 18:06:17","TRT02EDTM":"2022-03-23 00:06:17","AP01SDTM":"2019-03-23 06:06:17","AP01EDTM":"2021-03-22 18:06:17","AP02SDTM":"2021-03-22 18:06:17","AP02EDTM":"2022-03-23 00:06:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-23","EOSDY":1096,"LSTALVDT":"2022-04-12","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1501,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.73777,"AVALU":"mg/L","BASE2":9.2646,"BASE":8.73143,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.52683,"PCHG2":-5.68647,"CHG":0.00634,"PCHG":0.07255,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-09 06:06:17","ADY":992,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-102","SUBJID":"id-102","SITEID":"CHN-13","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.04895,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-23","TRTSDTM":"2019-03-23 06:06:17","TRTEDTM":"2022-03-23 00:06:17","TRT01SDTM":"2019-03-23 06:06:17","TRT01EDTM":"2021-03-22 18:06:17","TRT02SDTM":"2021-03-22 18:06:17","TRT02EDTM":"2022-03-23 00:06:17","AP01SDTM":"2019-03-23 06:06:17","AP01EDTM":"2021-03-22 18:06:17","AP02SDTM":"2021-03-22 18:06:17","AP02EDTM":"2022-03-23 00:06:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-23","EOSDY":1096,"LSTALVDT":"2022-04-12","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4204,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94966,"AVALU":"g/L","BASE2":2.94966,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-06 06:06:17","ADY":105,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-102","SUBJID":"id-102","SITEID":"CHN-13","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.04895,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-23","TRTSDTM":"2019-03-23 06:06:17","TRTEDTM":"2022-03-23 00:06:17","TRT01SDTM":"2019-03-23 06:06:17","TRT01EDTM":"2021-03-22 18:06:17","TRT02SDTM":"2021-03-22 18:06:17","TRT02EDTM":"2022-03-23 00:06:17","AP01SDTM":"2019-03-23 06:06:17","AP01EDTM":"2021-03-22 18:06:17","AP02SDTM":"2021-03-22 18:06:17","AP02EDTM":"2022-03-23 00:06:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-23","EOSDY":1096,"LSTALVDT":"2022-04-12","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2751,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85187,"AVALU":"g/L","BASE2":2.94966,"BASE":2.85187,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.09779,"PCHG2":-3.31542,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-07 06:06:17","ADY":137,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-102","SUBJID":"id-102","SITEID":"CHN-13","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.04895,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-23","TRTSDTM":"2019-03-23 06:06:17","TRTEDTM":"2022-03-23 00:06:17","TRT01SDTM":"2019-03-23 06:06:17","TRT01EDTM":"2021-03-22 18:06:17","TRT02SDTM":"2021-03-22 18:06:17","TRT02EDTM":"2022-03-23 00:06:17","AP01SDTM":"2019-03-23 06:06:17","AP01EDTM":"2021-03-22 18:06:17","AP02SDTM":"2021-03-22 18:06:17","AP02EDTM":"2022-03-23 00:06:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-23","EOSDY":1096,"LSTALVDT":"2022-04-12","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3934,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82845,"AVALU":"g/L","BASE2":2.94966,"BASE":2.85187,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12121,"PCHG2":-4.10922,"CHG":-0.02341,"PCHG":-0.82102,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-23 06:06:17","ADY":427,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-102","SUBJID":"id-102","SITEID":"CHN-13","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.04895,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-23","TRTSDTM":"2019-03-23 06:06:17","TRTEDTM":"2022-03-23 00:06:17","TRT01SDTM":"2019-03-23 06:06:17","TRT01EDTM":"2021-03-22 18:06:17","TRT02SDTM":"2021-03-22 18:06:17","TRT02EDTM":"2022-03-23 00:06:17","AP01SDTM":"2019-03-23 06:06:17","AP01EDTM":"2021-03-22 18:06:17","AP02SDTM":"2021-03-22 18:06:17","AP02EDTM":"2022-03-23 00:06:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-23","EOSDY":1096,"LSTALVDT":"2022-04-12","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2322,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83392,"AVALU":"g/L","BASE2":2.94966,"BASE":2.85187,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11574,"PCHG2":-3.92388,"CHG":-0.01795,"PCHG":-0.62933,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-16 06:06:17","ADY":451,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-102","SUBJID":"id-102","SITEID":"CHN-13","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.04895,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-23","TRTSDTM":"2019-03-23 06:06:17","TRTEDTM":"2022-03-23 00:06:17","TRT01SDTM":"2019-03-23 06:06:17","TRT01EDTM":"2021-03-22 18:06:17","TRT02SDTM":"2021-03-22 18:06:17","TRT02EDTM":"2022-03-23 00:06:17","AP01SDTM":"2019-03-23 06:06:17","AP01EDTM":"2021-03-22 18:06:17","AP02SDTM":"2021-03-22 18:06:17","AP02EDTM":"2022-03-23 00:06:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-23","EOSDY":1096,"LSTALVDT":"2022-04-12","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7395,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.1794,"AVALU":"g/L","BASE2":2.94966,"BASE":2.85187,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.22974,"PCHG2":7.78877,"CHG":0.32754,"PCHG":11.48496,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-07-28 06:06:17","ADY":493,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-102","SUBJID":"id-102","SITEID":"CHN-13","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.04895,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-23","TRTSDTM":"2019-03-23 06:06:17","TRTEDTM":"2022-03-23 00:06:17","TRT01SDTM":"2019-03-23 06:06:17","TRT01EDTM":"2021-03-22 18:06:17","TRT02SDTM":"2021-03-22 18:06:17","TRT02EDTM":"2022-03-23 00:06:17","AP01SDTM":"2019-03-23 06:06:17","AP01EDTM":"2021-03-22 18:06:17","AP02SDTM":"2021-03-22 18:06:17","AP02EDTM":"2022-03-23 00:06:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-23","EOSDY":1096,"LSTALVDT":"2022-04-12","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2456,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92396,"AVALU":"g/L","BASE2":2.94966,"BASE":2.85187,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0257,"PCHG2":-0.87139,"CHG":0.07209,"PCHG":2.52784,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-10 06:06:17","ADY":902,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-102","SUBJID":"id-102","SITEID":"CHN-13","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.04895,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-23","TRTSDTM":"2019-03-23 06:06:17","TRTEDTM":"2022-03-23 00:06:17","TRT01SDTM":"2019-03-23 06:06:17","TRT01EDTM":"2021-03-22 18:06:17","TRT02SDTM":"2021-03-22 18:06:17","TRT02EDTM":"2022-03-23 00:06:17","AP01SDTM":"2019-03-23 06:06:17","AP01EDTM":"2021-03-22 18:06:17","AP02SDTM":"2021-03-22 18:06:17","AP02EDTM":"2022-03-23 00:06:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-23","EOSDY":1096,"LSTALVDT":"2022-04-12","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2899,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03847,"AVALU":"g/L","BASE2":2.94966,"BASE":2.85187,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08881,"PCHG2":3.01084,"CHG":0.1866,"PCHG":6.5432,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-12-09 06:06:17","ADY":992,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-166","SUBJID":"id-166","SITEID":"CHN-13","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":10.57965,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-06-30 22:40:23","TRTEDTM":"2023-07-01 16:40:23","TRT01SDTM":"2020-06-30 22:40:23","TRT01EDTM":"2022-07-01 10:40:23","TRT02SDTM":"2022-07-01 10:40:23","TRT02EDTM":"2023-07-01 16:40:23","AP01SDTM":"2020-06-30 22:40:23","AP01EDTM":"2022-07-01 10:40:23","AP02SDTM":"2022-07-01 10:40:23","AP02EDTM":"2023-07-01 16:40:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-01","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5626,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":44.49167,"AVALU":"U/L","BASE2":44.49167,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-19 22:40:23","ADY":203,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-166","SUBJID":"id-166","SITEID":"CHN-13","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":10.57965,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-06-30 22:40:23","TRTEDTM":"2023-07-01 16:40:23","TRT01SDTM":"2020-06-30 22:40:23","TRT01EDTM":"2022-07-01 10:40:23","TRT02SDTM":"2022-07-01 10:40:23","TRT02EDTM":"2023-07-01 16:40:23","AP01SDTM":"2020-06-30 22:40:23","AP01EDTM":"2022-07-01 10:40:23","AP02SDTM":"2022-07-01 10:40:23","AP02EDTM":"2023-07-01 16:40:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-01","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1955,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.1596,"AVALU":"U/L","BASE2":44.49167,"BASE":9.1596,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-35.33207,"PCHG2":-79.41278,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-01 22:40:23","ADY":428,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-166","SUBJID":"id-166","SITEID":"CHN-13","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":10.57965,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-06-30 22:40:23","TRTEDTM":"2023-07-01 16:40:23","TRT01SDTM":"2020-06-30 22:40:23","TRT01EDTM":"2022-07-01 10:40:23","TRT02SDTM":"2022-07-01 10:40:23","TRT02EDTM":"2023-07-01 16:40:23","AP01SDTM":"2020-06-30 22:40:23","AP01EDTM":"2022-07-01 10:40:23","AP02SDTM":"2022-07-01 10:40:23","AP02EDTM":"2023-07-01 16:40:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-01","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1063,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.6149,"AVALU":"U/L","BASE2":44.49167,"BASE":9.1596,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-30.87677,"PCHG2":-69.39899,"CHG":4.4553,"PCHG":48.64077,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-03 22:40:23","ADY":430,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-166","SUBJID":"id-166","SITEID":"CHN-13","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":10.57965,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-06-30 22:40:23","TRTEDTM":"2023-07-01 16:40:23","TRT01SDTM":"2020-06-30 22:40:23","TRT01EDTM":"2022-07-01 10:40:23","TRT02SDTM":"2022-07-01 10:40:23","TRT02EDTM":"2023-07-01 16:40:23","AP01SDTM":"2020-06-30 22:40:23","AP01EDTM":"2022-07-01 10:40:23","AP02SDTM":"2022-07-01 10:40:23","AP02EDTM":"2023-07-01 16:40:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-01","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7994,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.14279,"AVALU":"U/L","BASE2":44.49167,"BASE":9.1596,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-26.34888,"PCHG2":-59.22205,"CHG":8.98319,"PCHG":98.07405,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-26 22:40:23","ADY":606,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-166","SUBJID":"id-166","SITEID":"CHN-13","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":10.57965,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-06-30 22:40:23","TRTEDTM":"2023-07-01 16:40:23","TRT01SDTM":"2020-06-30 22:40:23","TRT01EDTM":"2022-07-01 10:40:23","TRT02SDTM":"2022-07-01 10:40:23","TRT02EDTM":"2023-07-01 16:40:23","AP01SDTM":"2020-06-30 22:40:23","AP01EDTM":"2022-07-01 10:40:23","AP02SDTM":"2022-07-01 10:40:23","AP02EDTM":"2023-07-01 16:40:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-01","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1646,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.3379,"AVALU":"U/L","BASE2":44.49167,"BASE":9.1596,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.15377,"PCHG2":-29.56456,"CHG":22.1783,"PCHG":242.13179,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-27 22:40:23","ADY":880,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-166","SUBJID":"id-166","SITEID":"CHN-13","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":10.57965,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-06-30 22:40:23","TRTEDTM":"2023-07-01 16:40:23","TRT01SDTM":"2020-06-30 22:40:23","TRT01EDTM":"2022-07-01 10:40:23","TRT02SDTM":"2022-07-01 10:40:23","TRT02EDTM":"2023-07-01 16:40:23","AP01SDTM":"2020-06-30 22:40:23","AP01EDTM":"2022-07-01 10:40:23","AP02SDTM":"2022-07-01 10:40:23","AP02EDTM":"2023-07-01 16:40:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-01","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2966,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":44.95584,"AVALU":"U/L","BASE2":44.49167,"BASE":9.1596,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.46417,"PCHG2":1.04327,"CHG":35.79624,"PCHG":390.80568,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-05 22:40:23","ADY":919,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-166","SUBJID":"id-166","SITEID":"CHN-13","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":10.57965,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-06-30 22:40:23","TRTEDTM":"2023-07-01 16:40:23","TRT01SDTM":"2020-06-30 22:40:23","TRT01EDTM":"2022-07-01 10:40:23","TRT02SDTM":"2022-07-01 10:40:23","TRT02EDTM":"2023-07-01 16:40:23","AP01SDTM":"2020-06-30 22:40:23","AP01EDTM":"2022-07-01 10:40:23","AP02SDTM":"2022-07-01 10:40:23","AP02EDTM":"2023-07-01 16:40:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-01","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6867,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.36936,"AVALU":"U/L","BASE2":44.49167,"BASE":9.1596,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-34.12231,"PCHG2":-76.6937,"CHG":1.20976,"PCHG":13.20758,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-27 22:40:23","ADY":1000,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-166","SUBJID":"id-166","SITEID":"CHN-13","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":10.57965,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-06-30 22:40:23","TRTEDTM":"2023-07-01 16:40:23","TRT01SDTM":"2020-06-30 22:40:23","TRT01EDTM":"2022-07-01 10:40:23","TRT02SDTM":"2022-07-01 10:40:23","TRT02EDTM":"2023-07-01 16:40:23","AP01SDTM":"2020-06-30 22:40:23","AP01EDTM":"2022-07-01 10:40:23","AP02SDTM":"2022-07-01 10:40:23","AP02EDTM":"2023-07-01 16:40:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-01","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4794,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.35602,"AVALU":"mg/L","BASE2":7.35602,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"-4","BTOXGR":"2","ADTM":"2021-01-19 22:40:23","ADY":203,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-166","SUBJID":"id-166","SITEID":"CHN-13","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":10.57965,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-06-30 22:40:23","TRTEDTM":"2023-07-01 16:40:23","TRT01SDTM":"2020-06-30 22:40:23","TRT01EDTM":"2022-07-01 10:40:23","TRT02SDTM":"2022-07-01 10:40:23","TRT02EDTM":"2023-07-01 16:40:23","AP01SDTM":"2020-06-30 22:40:23","AP01EDTM":"2022-07-01 10:40:23","AP02SDTM":"2022-07-01 10:40:23","AP02EDTM":"2023-07-01 16:40:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-01","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5247,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.63983,"AVALU":"mg/L","BASE2":7.35602,"BASE":10.63983,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":3.28381,"PCHG2":44.64108,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2021-09-01 22:40:23","ADY":428,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-166","SUBJID":"id-166","SITEID":"CHN-13","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":10.57965,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-06-30 22:40:23","TRTEDTM":"2023-07-01 16:40:23","TRT01SDTM":"2020-06-30 22:40:23","TRT01EDTM":"2022-07-01 10:40:23","TRT02SDTM":"2022-07-01 10:40:23","TRT02EDTM":"2023-07-01 16:40:23","AP01SDTM":"2020-06-30 22:40:23","AP01EDTM":"2022-07-01 10:40:23","AP02SDTM":"2022-07-01 10:40:23","AP02EDTM":"2023-07-01 16:40:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-01","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8309,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.25276,"AVALU":"mg/L","BASE2":7.35602,"BASE":10.63983,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.89673,"PCHG2":25.78478,"CHG":-1.38707,"PCHG":-13.03662,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-09-03 22:40:23","ADY":430,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-166","SUBJID":"id-166","SITEID":"CHN-13","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":10.57965,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-06-30 22:40:23","TRTEDTM":"2023-07-01 16:40:23","TRT01SDTM":"2020-06-30 22:40:23","TRT01EDTM":"2022-07-01 10:40:23","TRT02SDTM":"2022-07-01 10:40:23","TRT02EDTM":"2023-07-01 16:40:23","AP01SDTM":"2020-06-30 22:40:23","AP01EDTM":"2022-07-01 10:40:23","AP02SDTM":"2022-07-01 10:40:23","AP02EDTM":"2023-07-01 16:40:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-01","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4811,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.37085,"AVALU":"mg/L","BASE2":7.35602,"BASE":10.63983,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.01482,"PCHG2":13.7958,"CHG":-2.26899,"PCHG":-21.3254,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-02-26 22:40:23","ADY":606,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-166","SUBJID":"id-166","SITEID":"CHN-13","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":10.57965,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-06-30 22:40:23","TRTEDTM":"2023-07-01 16:40:23","TRT01SDTM":"2020-06-30 22:40:23","TRT01EDTM":"2022-07-01 10:40:23","TRT02SDTM":"2022-07-01 10:40:23","TRT02EDTM":"2023-07-01 16:40:23","AP01SDTM":"2020-06-30 22:40:23","AP01EDTM":"2022-07-01 10:40:23","AP02SDTM":"2022-07-01 10:40:23","AP02EDTM":"2023-07-01 16:40:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-01","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7621,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.42284,"AVALU":"mg/L","BASE2":7.35602,"BASE":10.63983,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06681,"PCHG2":0.90827,"CHG":-3.217,"PCHG":-30.2354,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-3","BTOXGR":"2","ADTM":"2022-11-27 22:40:23","ADY":880,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-166","SUBJID":"id-166","SITEID":"CHN-13","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":10.57965,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-06-30 22:40:23","TRTEDTM":"2023-07-01 16:40:23","TRT01SDTM":"2020-06-30 22:40:23","TRT01EDTM":"2022-07-01 10:40:23","TRT02SDTM":"2022-07-01 10:40:23","TRT02EDTM":"2023-07-01 16:40:23","AP01SDTM":"2020-06-30 22:40:23","AP01EDTM":"2022-07-01 10:40:23","AP02SDTM":"2022-07-01 10:40:23","AP02EDTM":"2023-07-01 16:40:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-01","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2973,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.44079,"AVALU":"mg/L","BASE2":7.35602,"BASE":10.63983,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.08476,"PCHG2":28.34088,"CHG":-1.19905,"PCHG":-11.26941,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2023-01-05 22:40:23","ADY":919,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-166","SUBJID":"id-166","SITEID":"CHN-13","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":10.57965,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-06-30 22:40:23","TRTEDTM":"2023-07-01 16:40:23","TRT01SDTM":"2020-06-30 22:40:23","TRT01EDTM":"2022-07-01 10:40:23","TRT02SDTM":"2022-07-01 10:40:23","TRT02EDTM":"2023-07-01 16:40:23","AP01SDTM":"2020-06-30 22:40:23","AP01EDTM":"2022-07-01 10:40:23","AP02SDTM":"2022-07-01 10:40:23","AP02EDTM":"2023-07-01 16:40:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-01","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2940,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.14724,"AVALU":"mg/L","BASE2":7.35602,"BASE":10.63983,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.79121,"PCHG2":10.75601,"CHG":-2.49259,"PCHG":-23.42701,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2023-03-27 22:40:23","ADY":1000,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-166","SUBJID":"id-166","SITEID":"CHN-13","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":10.57965,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-06-30 22:40:23","TRTEDTM":"2023-07-01 16:40:23","TRT01SDTM":"2020-06-30 22:40:23","TRT01EDTM":"2022-07-01 10:40:23","TRT02SDTM":"2022-07-01 10:40:23","TRT02EDTM":"2023-07-01 16:40:23","AP01SDTM":"2020-06-30 22:40:23","AP01EDTM":"2022-07-01 10:40:23","AP02SDTM":"2022-07-01 10:40:23","AP02EDTM":"2023-07-01 16:40:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-01","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1546,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7784,"AVALU":"g/L","BASE2":2.7784,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-19 22:40:23","ADY":203,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-166","SUBJID":"id-166","SITEID":"CHN-13","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":10.57965,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-06-30 22:40:23","TRTEDTM":"2023-07-01 16:40:23","TRT01SDTM":"2020-06-30 22:40:23","TRT01EDTM":"2022-07-01 10:40:23","TRT02SDTM":"2022-07-01 10:40:23","TRT02EDTM":"2023-07-01 16:40:23","AP01SDTM":"2020-06-30 22:40:23","AP01EDTM":"2022-07-01 10:40:23","AP02SDTM":"2022-07-01 10:40:23","AP02EDTM":"2023-07-01 16:40:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-01","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3080,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88768,"AVALU":"g/L","BASE2":2.7784,"BASE":2.88768,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.10927,"PCHG2":3.93292,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-01 22:40:23","ADY":428,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-166","SUBJID":"id-166","SITEID":"CHN-13","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":10.57965,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-06-30 22:40:23","TRTEDTM":"2023-07-01 16:40:23","TRT01SDTM":"2020-06-30 22:40:23","TRT01EDTM":"2022-07-01 10:40:23","TRT02SDTM":"2022-07-01 10:40:23","TRT02EDTM":"2023-07-01 16:40:23","AP01SDTM":"2020-06-30 22:40:23","AP01EDTM":"2022-07-01 10:40:23","AP02SDTM":"2022-07-01 10:40:23","AP02EDTM":"2023-07-01 16:40:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-01","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8399,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83209,"AVALU":"g/L","BASE2":2.7784,"BASE":2.88768,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05369,"PCHG2":1.93228,"CHG":-0.05559,"PCHG":-1.92494,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-03 22:40:23","ADY":430,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-166","SUBJID":"id-166","SITEID":"CHN-13","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":10.57965,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-06-30 22:40:23","TRTEDTM":"2023-07-01 16:40:23","TRT01SDTM":"2020-06-30 22:40:23","TRT01EDTM":"2022-07-01 10:40:23","TRT02SDTM":"2022-07-01 10:40:23","TRT02EDTM":"2023-07-01 16:40:23","AP01SDTM":"2020-06-30 22:40:23","AP01EDTM":"2022-07-01 10:40:23","AP02SDTM":"2022-07-01 10:40:23","AP02EDTM":"2023-07-01 16:40:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-01","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7605,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89269,"AVALU":"g/L","BASE2":2.7784,"BASE":2.88768,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11429,"PCHG2":4.11342,"CHG":0.00501,"PCHG":0.17367,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-26 22:40:23","ADY":606,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-166","SUBJID":"id-166","SITEID":"CHN-13","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":10.57965,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-06-30 22:40:23","TRTEDTM":"2023-07-01 16:40:23","TRT01SDTM":"2020-06-30 22:40:23","TRT01EDTM":"2022-07-01 10:40:23","TRT02SDTM":"2022-07-01 10:40:23","TRT02EDTM":"2023-07-01 16:40:23","AP01SDTM":"2020-06-30 22:40:23","AP01EDTM":"2022-07-01 10:40:23","AP02SDTM":"2022-07-01 10:40:23","AP02EDTM":"2023-07-01 16:40:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-01","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1910,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04982,"AVALU":"g/L","BASE2":2.7784,"BASE":2.88768,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.27142,"PCHG2":9.76896,"CHG":0.16215,"PCHG":5.6152,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-11-27 22:40:23","ADY":880,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-166","SUBJID":"id-166","SITEID":"CHN-13","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":10.57965,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-06-30 22:40:23","TRTEDTM":"2023-07-01 16:40:23","TRT01SDTM":"2020-06-30 22:40:23","TRT01EDTM":"2022-07-01 10:40:23","TRT02SDTM":"2022-07-01 10:40:23","TRT02EDTM":"2023-07-01 16:40:23","AP01SDTM":"2020-06-30 22:40:23","AP01EDTM":"2022-07-01 10:40:23","AP02SDTM":"2022-07-01 10:40:23","AP02EDTM":"2023-07-01 16:40:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-01","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5805,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0899,"AVALU":"g/L","BASE2":2.7784,"BASE":2.88768,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.3115,"PCHG2":11.21142,"CHG":0.20223,"PCHG":7.00308,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2023-01-05 22:40:23","ADY":919,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-166","SUBJID":"id-166","SITEID":"CHN-13","AGE":43,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":10.57965,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-30","TRTSDTM":"2020-06-30 22:40:23","TRTEDTM":"2023-07-01 16:40:23","TRT01SDTM":"2020-06-30 22:40:23","TRT01EDTM":"2022-07-01 10:40:23","TRT02SDTM":"2022-07-01 10:40:23","TRT02EDTM":"2023-07-01 16:40:23","AP01SDTM":"2020-06-30 22:40:23","AP01EDTM":"2022-07-01 10:40:23","AP02SDTM":"2022-07-01 10:40:23","AP02EDTM":"2023-07-01 16:40:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-01","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7859,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77277,"AVALU":"g/L","BASE2":2.7784,"BASE":2.88768,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00563,"PCHG2":-0.2028,"CHG":-0.11491,"PCHG":-3.97922,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-27 22:40:23","ADY":1000,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-19","SUBJID":"id-19","SITEID":"CHN-13","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.95167,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 05:40:12","TRT01SDTM":"2019-10-13 05:40:12","AP01SDTM":"2019-10-13 05:40:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5739,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.94043,"AVALU":"U/L","BASE2":12.94043,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-31 05:40:12","ADY":18,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-19","SUBJID":"id-19","SITEID":"CHN-13","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.95167,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 05:40:12","TRT01SDTM":"2019-10-13 05:40:12","AP01SDTM":"2019-10-13 05:40:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2977,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.49316,"AVALU":"U/L","BASE2":12.94043,"BASE":14.49316,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.55273,"PCHG2":11.99909,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-20 05:40:12","ADY":68,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-19","SUBJID":"id-19","SITEID":"CHN-13","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.95167,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 05:40:12","TRT01SDTM":"2019-10-13 05:40:12","AP01SDTM":"2019-10-13 05:40:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3710,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.35155,"AVALU":"U/L","BASE2":12.94043,"BASE":14.49316,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.41112,"PCHG2":41.81565,"CHG":3.85839,"PCHG":26.62215,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-08 05:40:12","ADY":331,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-19","SUBJID":"id-19","SITEID":"CHN-13","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.95167,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 05:40:12","TRT01SDTM":"2019-10-13 05:40:12","AP01SDTM":"2019-10-13 05:40:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3732,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.73214,"AVALU":"U/L","BASE2":12.94043,"BASE":14.49316,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.79171,"PCHG2":6.11812,"CHG":-0.76102,"PCHG":-5.25091,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-09 05:40:12","ADY":393,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-19","SUBJID":"id-19","SITEID":"CHN-13","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.95167,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 05:40:12","TRT01SDTM":"2019-10-13 05:40:12","AP01SDTM":"2019-10-13 05:40:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4064,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":35.56431,"AVALU":"U/L","BASE2":12.94043,"BASE":14.49316,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":22.62388,"PCHG2":174.83106,"CHG":21.07115,"PCHG":145.38688,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-05 05:40:12","ADY":481,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-19","SUBJID":"id-19","SITEID":"CHN-13","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.95167,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 05:40:12","TRT01SDTM":"2019-10-13 05:40:12","AP01SDTM":"2019-10-13 05:40:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1781,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.60938,"AVALU":"U/L","BASE2":12.94043,"BASE":14.49316,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.33104,"PCHG2":-18.01364,"CHG":-3.88377,"PCHG":-26.7973,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-25 05:40:12","ADY":529,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-19","SUBJID":"id-19","SITEID":"CHN-13","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.95167,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 05:40:12","TRT01SDTM":"2019-10-13 05:40:12","AP01SDTM":"2019-10-13 05:40:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3008,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.10999,"AVALU":"U/L","BASE2":12.94043,"BASE":14.49316,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":20.16957,"PCHG2":155.86478,"CHG":18.61683,"PCHG":128.45256,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-03 05:40:12","ADY":599,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-19","SUBJID":"id-19","SITEID":"CHN-13","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.95167,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 05:40:12","TRT01SDTM":"2019-10-13 05:40:12","AP01SDTM":"2019-10-13 05:40:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7918,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.92056,"AVALU":"mg/L","BASE2":8.92056,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-31 05:40:12","ADY":18,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-19","SUBJID":"id-19","SITEID":"CHN-13","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.95167,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 05:40:12","TRT01SDTM":"2019-10-13 05:40:12","AP01SDTM":"2019-10-13 05:40:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3139,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.30543,"AVALU":"mg/L","BASE2":8.92056,"BASE":9.30543,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.38486,"PCHG2":4.31433,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-20 05:40:12","ADY":68,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-19","SUBJID":"id-19","SITEID":"CHN-13","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.95167,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 05:40:12","TRT01SDTM":"2019-10-13 05:40:12","AP01SDTM":"2019-10-13 05:40:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5721,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.01578,"AVALU":"mg/L","BASE2":8.92056,"BASE":9.30543,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09522,"PCHG2":1.06738,"CHG":-0.28965,"PCHG":-3.11266,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-08 05:40:12","ADY":331,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-19","SUBJID":"id-19","SITEID":"CHN-13","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.95167,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 05:40:12","TRT01SDTM":"2019-10-13 05:40:12","AP01SDTM":"2019-10-13 05:40:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1420,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.1328,"AVALU":"mg/L","BASE2":8.92056,"BASE":9.30543,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.78777,"PCHG2":-20.04097,"CHG":-2.17263,"PCHG":-23.34799,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-11-09 05:40:12","ADY":393,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-19","SUBJID":"id-19","SITEID":"CHN-13","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.95167,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 05:40:12","TRT01SDTM":"2019-10-13 05:40:12","AP01SDTM":"2019-10-13 05:40:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":300,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.63515,"AVALU":"mg/L","BASE2":8.92056,"BASE":9.30543,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.28542,"PCHG2":-14.40959,"CHG":-1.67028,"PCHG":-17.94952,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-02-05 05:40:12","ADY":481,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-19","SUBJID":"id-19","SITEID":"CHN-13","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.95167,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 05:40:12","TRT01SDTM":"2019-10-13 05:40:12","AP01SDTM":"2019-10-13 05:40:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5667,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.71038,"AVALU":"mg/L","BASE2":8.92056,"BASE":9.30543,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.78982,"PCHG2":8.85391,"CHG":0.40496,"PCHG":4.35183,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-25 05:40:12","ADY":529,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-19","SUBJID":"id-19","SITEID":"CHN-13","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.95167,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 05:40:12","TRT01SDTM":"2019-10-13 05:40:12","AP01SDTM":"2019-10-13 05:40:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4691,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.16365,"AVALU":"mg/L","BASE2":8.92056,"BASE":9.30543,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.24309,"PCHG2":13.93508,"CHG":0.85823,"PCHG":9.22284,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-06-03 05:40:12","ADY":599,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-19","SUBJID":"id-19","SITEID":"CHN-13","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.95167,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 05:40:12","TRT01SDTM":"2019-10-13 05:40:12","AP01SDTM":"2019-10-13 05:40:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3816,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77722,"AVALU":"g/L","BASE2":2.77722,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-31 05:40:12","ADY":18,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-19","SUBJID":"id-19","SITEID":"CHN-13","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.95167,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 05:40:12","TRT01SDTM":"2019-10-13 05:40:12","AP01SDTM":"2019-10-13 05:40:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7406,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95599,"AVALU":"g/L","BASE2":2.77722,"BASE":2.95599,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.17877,"PCHG2":6.43705,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-20 05:40:12","ADY":68,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-19","SUBJID":"id-19","SITEID":"CHN-13","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.95167,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 05:40:12","TRT01SDTM":"2019-10-13 05:40:12","AP01SDTM":"2019-10-13 05:40:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":769,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78956,"AVALU":"g/L","BASE2":2.77722,"BASE":2.95599,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01234,"PCHG2":0.44432,"CHG":-0.16643,"PCHG":-5.63031,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-08 05:40:12","ADY":331,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-19","SUBJID":"id-19","SITEID":"CHN-13","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.95167,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 05:40:12","TRT01SDTM":"2019-10-13 05:40:12","AP01SDTM":"2019-10-13 05:40:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6453,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.09954,"AVALU":"g/L","BASE2":2.77722,"BASE":2.95599,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.32232,"PCHG2":11.60585,"CHG":0.14355,"PCHG":4.8562,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-11-09 05:40:12","ADY":393,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-19","SUBJID":"id-19","SITEID":"CHN-13","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.95167,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 05:40:12","TRT01SDTM":"2019-10-13 05:40:12","AP01SDTM":"2019-10-13 05:40:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8252,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81657,"AVALU":"g/L","BASE2":2.77722,"BASE":2.95599,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03934,"PCHG2":1.41664,"CHG":-0.13943,"PCHG":-4.71679,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-05 05:40:12","ADY":481,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-19","SUBJID":"id-19","SITEID":"CHN-13","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.95167,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 05:40:12","TRT01SDTM":"2019-10-13 05:40:12","AP01SDTM":"2019-10-13 05:40:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5789,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98882,"AVALU":"g/L","BASE2":2.77722,"BASE":2.95599,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.2116,"PCHG2":7.61903,"CHG":0.03283,"PCHG":1.1105,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-25 05:40:12","ADY":529,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-19","SUBJID":"id-19","SITEID":"CHN-13","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.95167,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-13 05:40:12","TRT01SDTM":"2019-10-13 05:40:12","AP01SDTM":"2019-10-13 05:40:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5755,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92317,"AVALU":"g/L","BASE2":2.77722,"BASE":2.95599,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14595,"PCHG2":5.25515,"CHG":-0.03282,"PCHG":-1.11043,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-03 05:40:12","ADY":599,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-239","SUBJID":"id-239","SITEID":"CHN-13","AGE":58,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.44252,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-05","TRTSDTM":"2020-11-06 22:37:43","TRTEDTM":"2023-11-07 16:37:43","TRT01SDTM":"2020-11-06 22:37:43","TRT01EDTM":"2022-11-07 10:37:43","TRT02SDTM":"2022-11-07 10:37:43","TRT02EDTM":"2023-11-07 16:37:43","AP01SDTM":"2020-11-06 22:37:43","AP01EDTM":"2022-11-07 10:37:43","AP02SDTM":"2022-11-07 10:37:43","AP02EDTM":"2023-11-07 16:37:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-07","EOSDY":1096,"LSTALVDT":"2023-12-01","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5960,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.46211,"AVALU":"U/L","BASE2":20.46211,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-09 22:37:43","ADY":64,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-239","SUBJID":"id-239","SITEID":"CHN-13","AGE":58,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.44252,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-05","TRTSDTM":"2020-11-06 22:37:43","TRTEDTM":"2023-11-07 16:37:43","TRT01SDTM":"2020-11-06 22:37:43","TRT01EDTM":"2022-11-07 10:37:43","TRT02SDTM":"2022-11-07 10:37:43","TRT02EDTM":"2023-11-07 16:37:43","AP01SDTM":"2020-11-06 22:37:43","AP01EDTM":"2022-11-07 10:37:43","AP02SDTM":"2022-11-07 10:37:43","AP02EDTM":"2023-11-07 16:37:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-07","EOSDY":1096,"LSTALVDT":"2023-12-01","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7966,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.07915,"AVALU":"U/L","BASE2":20.46211,"BASE":15.07915,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-5.38296,"PCHG2":-26.30698,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-09 22:37:43","ADY":853,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-239","SUBJID":"id-239","SITEID":"CHN-13","AGE":58,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.44252,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-05","TRTSDTM":"2020-11-06 22:37:43","TRTEDTM":"2023-11-07 16:37:43","TRT01SDTM":"2020-11-06 22:37:43","TRT01EDTM":"2022-11-07 10:37:43","TRT02SDTM":"2022-11-07 10:37:43","TRT02EDTM":"2023-11-07 16:37:43","AP01SDTM":"2020-11-06 22:37:43","AP01EDTM":"2022-11-07 10:37:43","AP02SDTM":"2022-11-07 10:37:43","AP02EDTM":"2023-11-07 16:37:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-07","EOSDY":1096,"LSTALVDT":"2023-12-01","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6551,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.62979,"AVALU":"U/L","BASE2":20.46211,"BASE":15.07915,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.16768,"PCHG2":69.2386,"CHG":19.55064,"PCHG":129.6535,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-29 22:37:43","ADY":904,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-239","SUBJID":"id-239","SITEID":"CHN-13","AGE":58,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.44252,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-05","TRTSDTM":"2020-11-06 22:37:43","TRTEDTM":"2023-11-07 16:37:43","TRT01SDTM":"2020-11-06 22:37:43","TRT01EDTM":"2022-11-07 10:37:43","TRT02SDTM":"2022-11-07 10:37:43","TRT02EDTM":"2023-11-07 16:37:43","AP01SDTM":"2020-11-06 22:37:43","AP01EDTM":"2022-11-07 10:37:43","AP02SDTM":"2022-11-07 10:37:43","AP02EDTM":"2023-11-07 16:37:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-07","EOSDY":1096,"LSTALVDT":"2023-12-01","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8332,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.71377,"AVALU":"U/L","BASE2":20.46211,"BASE":15.07915,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.25166,"PCHG2":30.55237,"CHG":11.63462,"PCHG":77.15704,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-01 22:37:43","ADY":967,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-239","SUBJID":"id-239","SITEID":"CHN-13","AGE":58,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.44252,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-05","TRTSDTM":"2020-11-06 22:37:43","TRTEDTM":"2023-11-07 16:37:43","TRT01SDTM":"2020-11-06 22:37:43","TRT01EDTM":"2022-11-07 10:37:43","TRT02SDTM":"2022-11-07 10:37:43","TRT02EDTM":"2023-11-07 16:37:43","AP01SDTM":"2020-11-06 22:37:43","AP01EDTM":"2022-11-07 10:37:43","AP02SDTM":"2022-11-07 10:37:43","AP02EDTM":"2023-11-07 16:37:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-07","EOSDY":1096,"LSTALVDT":"2023-12-01","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3472,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.12967,"AVALU":"U/L","BASE2":20.46211,"BASE":15.07915,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.66757,"PCHG2":3.26245,"CHG":6.05053,"PCHG":40.12514,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-03 22:37:43","ADY":1000,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-239","SUBJID":"id-239","SITEID":"CHN-13","AGE":58,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.44252,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-05","TRTSDTM":"2020-11-06 22:37:43","TRTEDTM":"2023-11-07 16:37:43","TRT01SDTM":"2020-11-06 22:37:43","TRT01EDTM":"2022-11-07 10:37:43","TRT02SDTM":"2022-11-07 10:37:43","TRT02EDTM":"2023-11-07 16:37:43","AP01SDTM":"2020-11-06 22:37:43","AP01EDTM":"2022-11-07 10:37:43","AP02SDTM":"2022-11-07 10:37:43","AP02EDTM":"2023-11-07 16:37:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-07","EOSDY":1096,"LSTALVDT":"2023-12-01","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4040,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.34257,"AVALU":"U/L","BASE2":20.46211,"BASE":15.07915,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.88046,"PCHG2":53.17372,"CHG":16.26343,"PCHG":107.85377,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-03 22:37:43","ADY":1031,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-239","SUBJID":"id-239","SITEID":"CHN-13","AGE":58,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.44252,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-05","TRTSDTM":"2020-11-06 22:37:43","TRTEDTM":"2023-11-07 16:37:43","TRT01SDTM":"2020-11-06 22:37:43","TRT01EDTM":"2022-11-07 10:37:43","TRT02SDTM":"2022-11-07 10:37:43","TRT02EDTM":"2023-11-07 16:37:43","AP01SDTM":"2020-11-06 22:37:43","AP01EDTM":"2022-11-07 10:37:43","AP02SDTM":"2022-11-07 10:37:43","AP02EDTM":"2023-11-07 16:37:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-07","EOSDY":1096,"LSTALVDT":"2023-12-01","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5308,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.50185,"AVALU":"U/L","BASE2":20.46211,"BASE":15.07915,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.03974,"PCHG2":39.29089,"CHG":13.42271,"PCHG":89.01503,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-17 22:37:43","ADY":1045,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-239","SUBJID":"id-239","SITEID":"CHN-13","AGE":58,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.44252,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-05","TRTSDTM":"2020-11-06 22:37:43","TRTEDTM":"2023-11-07 16:37:43","TRT01SDTM":"2020-11-06 22:37:43","TRT01EDTM":"2022-11-07 10:37:43","TRT02SDTM":"2022-11-07 10:37:43","TRT02EDTM":"2023-11-07 16:37:43","AP01SDTM":"2020-11-06 22:37:43","AP01EDTM":"2022-11-07 10:37:43","AP02SDTM":"2022-11-07 10:37:43","AP02EDTM":"2023-11-07 16:37:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-07","EOSDY":1096,"LSTALVDT":"2023-12-01","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5311,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.11562,"AVALU":"mg/L","BASE2":9.11562,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-01-09 22:37:43","ADY":64,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-239","SUBJID":"id-239","SITEID":"CHN-13","AGE":58,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.44252,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-05","TRTSDTM":"2020-11-06 22:37:43","TRTEDTM":"2023-11-07 16:37:43","TRT01SDTM":"2020-11-06 22:37:43","TRT01EDTM":"2022-11-07 10:37:43","TRT02SDTM":"2022-11-07 10:37:43","TRT02EDTM":"2023-11-07 16:37:43","AP01SDTM":"2020-11-06 22:37:43","AP01EDTM":"2022-11-07 10:37:43","AP02SDTM":"2022-11-07 10:37:43","AP02EDTM":"2023-11-07 16:37:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-07","EOSDY":1096,"LSTALVDT":"2023-12-01","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4726,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.50071,"AVALU":"mg/L","BASE2":9.11562,"BASE":10.50071,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.3851,"PCHG2":15.19476,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2023-03-09 22:37:43","ADY":853,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-239","SUBJID":"id-239","SITEID":"CHN-13","AGE":58,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.44252,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-05","TRTSDTM":"2020-11-06 22:37:43","TRTEDTM":"2023-11-07 16:37:43","TRT01SDTM":"2020-11-06 22:37:43","TRT01EDTM":"2022-11-07 10:37:43","TRT02SDTM":"2022-11-07 10:37:43","TRT02EDTM":"2023-11-07 16:37:43","AP01SDTM":"2020-11-06 22:37:43","AP01EDTM":"2022-11-07 10:37:43","AP02SDTM":"2022-11-07 10:37:43","AP02EDTM":"2023-11-07 16:37:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-07","EOSDY":1096,"LSTALVDT":"2023-12-01","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7237,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.62222,"AVALU":"mg/L","BASE2":9.11562,"BASE":10.50071,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.50661,"PCHG2":5.55755,"CHG":-0.87849,"PCHG":-8.36601,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2023-04-29 22:37:43","ADY":904,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-239","SUBJID":"id-239","SITEID":"CHN-13","AGE":58,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.44252,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-05","TRTSDTM":"2020-11-06 22:37:43","TRTEDTM":"2023-11-07 16:37:43","TRT01SDTM":"2020-11-06 22:37:43","TRT01EDTM":"2022-11-07 10:37:43","TRT02SDTM":"2022-11-07 10:37:43","TRT02EDTM":"2023-11-07 16:37:43","AP01SDTM":"2020-11-06 22:37:43","AP01EDTM":"2022-11-07 10:37:43","AP02SDTM":"2022-11-07 10:37:43","AP02EDTM":"2023-11-07 16:37:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-07","EOSDY":1096,"LSTALVDT":"2023-12-01","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5859,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.05062,"AVALU":"mg/L","BASE2":9.11562,"BASE":10.50071,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.065,"PCHG2":-11.68324,"CHG":-2.4501,"PCHG":-23.33266,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2023-07-01 22:37:43","ADY":967,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-239","SUBJID":"id-239","SITEID":"CHN-13","AGE":58,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.44252,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-05","TRTSDTM":"2020-11-06 22:37:43","TRTEDTM":"2023-11-07 16:37:43","TRT01SDTM":"2020-11-06 22:37:43","TRT01EDTM":"2022-11-07 10:37:43","TRT02SDTM":"2022-11-07 10:37:43","TRT02EDTM":"2023-11-07 16:37:43","AP01SDTM":"2020-11-06 22:37:43","AP01EDTM":"2022-11-07 10:37:43","AP02SDTM":"2022-11-07 10:37:43","AP02EDTM":"2023-11-07 16:37:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-07","EOSDY":1096,"LSTALVDT":"2023-12-01","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6255,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.04783,"AVALU":"mg/L","BASE2":9.11562,"BASE":10.50071,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.06779,"PCHG2":-11.71381,"CHG":-2.45288,"PCHG":-23.3592,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2023-08-03 22:37:43","ADY":1000,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-239","SUBJID":"id-239","SITEID":"CHN-13","AGE":58,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.44252,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-05","TRTSDTM":"2020-11-06 22:37:43","TRTEDTM":"2023-11-07 16:37:43","TRT01SDTM":"2020-11-06 22:37:43","TRT01EDTM":"2022-11-07 10:37:43","TRT02SDTM":"2022-11-07 10:37:43","TRT02EDTM":"2023-11-07 16:37:43","AP01SDTM":"2020-11-06 22:37:43","AP01EDTM":"2022-11-07 10:37:43","AP02SDTM":"2022-11-07 10:37:43","AP02EDTM":"2023-11-07 16:37:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-07","EOSDY":1096,"LSTALVDT":"2023-12-01","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":474,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.77856,"AVALU":"mg/L","BASE2":9.11562,"BASE":10.50071,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.33706,"PCHG2":-3.69757,"CHG":-1.72215,"PCHG":-16.40034,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2023-09-03 22:37:43","ADY":1031,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-239","SUBJID":"id-239","SITEID":"CHN-13","AGE":58,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.44252,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-05","TRTSDTM":"2020-11-06 22:37:43","TRTEDTM":"2023-11-07 16:37:43","TRT01SDTM":"2020-11-06 22:37:43","TRT01EDTM":"2022-11-07 10:37:43","TRT02SDTM":"2022-11-07 10:37:43","TRT02EDTM":"2023-11-07 16:37:43","AP01SDTM":"2020-11-06 22:37:43","AP01EDTM":"2022-11-07 10:37:43","AP02SDTM":"2022-11-07 10:37:43","AP02EDTM":"2023-11-07 16:37:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-07","EOSDY":1096,"LSTALVDT":"2023-12-01","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1390,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.37092,"AVALU":"mg/L","BASE2":9.11562,"BASE":10.50071,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.7447,"PCHG2":-8.16946,"CHG":-2.12979,"PCHG":-20.28237,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2023-09-17 22:37:43","ADY":1045,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-239","SUBJID":"id-239","SITEID":"CHN-13","AGE":58,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.44252,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-05","TRTSDTM":"2020-11-06 22:37:43","TRTEDTM":"2023-11-07 16:37:43","TRT01SDTM":"2020-11-06 22:37:43","TRT01EDTM":"2022-11-07 10:37:43","TRT02SDTM":"2022-11-07 10:37:43","TRT02EDTM":"2023-11-07 16:37:43","AP01SDTM":"2020-11-06 22:37:43","AP01EDTM":"2022-11-07 10:37:43","AP02SDTM":"2022-11-07 10:37:43","AP02EDTM":"2023-11-07 16:37:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-07","EOSDY":1096,"LSTALVDT":"2023-12-01","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":51,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98845,"AVALU":"g/L","BASE2":2.98845,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-09 22:37:43","ADY":64,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-239","SUBJID":"id-239","SITEID":"CHN-13","AGE":58,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.44252,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-05","TRTSDTM":"2020-11-06 22:37:43","TRTEDTM":"2023-11-07 16:37:43","TRT01SDTM":"2020-11-06 22:37:43","TRT01EDTM":"2022-11-07 10:37:43","TRT02SDTM":"2022-11-07 10:37:43","TRT02EDTM":"2023-11-07 16:37:43","AP01SDTM":"2020-11-06 22:37:43","AP01EDTM":"2022-11-07 10:37:43","AP02SDTM":"2022-11-07 10:37:43","AP02EDTM":"2023-11-07 16:37:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-07","EOSDY":1096,"LSTALVDT":"2023-12-01","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7997,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92042,"AVALU":"g/L","BASE2":2.98845,"BASE":2.92042,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.06803,"PCHG2":-2.27655,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-09 22:37:43","ADY":853,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-239","SUBJID":"id-239","SITEID":"CHN-13","AGE":58,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.44252,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-05","TRTSDTM":"2020-11-06 22:37:43","TRTEDTM":"2023-11-07 16:37:43","TRT01SDTM":"2020-11-06 22:37:43","TRT01EDTM":"2022-11-07 10:37:43","TRT02SDTM":"2022-11-07 10:37:43","TRT02EDTM":"2023-11-07 16:37:43","AP01SDTM":"2020-11-06 22:37:43","AP01EDTM":"2022-11-07 10:37:43","AP02SDTM":"2022-11-07 10:37:43","AP02EDTM":"2023-11-07 16:37:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-07","EOSDY":1096,"LSTALVDT":"2023-12-01","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6158,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83854,"AVALU":"g/L","BASE2":2.98845,"BASE":2.92042,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14992,"PCHG2":-5.01654,"CHG":-0.08188,"PCHG":-2.80381,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-29 22:37:43","ADY":904,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-239","SUBJID":"id-239","SITEID":"CHN-13","AGE":58,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.44252,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-05","TRTSDTM":"2020-11-06 22:37:43","TRTEDTM":"2023-11-07 16:37:43","TRT01SDTM":"2020-11-06 22:37:43","TRT01EDTM":"2022-11-07 10:37:43","TRT02SDTM":"2022-11-07 10:37:43","TRT02EDTM":"2023-11-07 16:37:43","AP01SDTM":"2020-11-06 22:37:43","AP01EDTM":"2022-11-07 10:37:43","AP02SDTM":"2022-11-07 10:37:43","AP02EDTM":"2023-11-07 16:37:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-07","EOSDY":1096,"LSTALVDT":"2023-12-01","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1617,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92369,"AVALU":"g/L","BASE2":2.98845,"BASE":2.92042,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06476,"PCHG2":-2.16708,"CHG":0.00327,"PCHG":0.11202,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-01 22:37:43","ADY":967,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-239","SUBJID":"id-239","SITEID":"CHN-13","AGE":58,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.44252,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-05","TRTSDTM":"2020-11-06 22:37:43","TRTEDTM":"2023-11-07 16:37:43","TRT01SDTM":"2020-11-06 22:37:43","TRT01EDTM":"2022-11-07 10:37:43","TRT02SDTM":"2022-11-07 10:37:43","TRT02EDTM":"2023-11-07 16:37:43","AP01SDTM":"2020-11-06 22:37:43","AP01EDTM":"2022-11-07 10:37:43","AP02SDTM":"2022-11-07 10:37:43","AP02EDTM":"2023-11-07 16:37:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-07","EOSDY":1096,"LSTALVDT":"2023-12-01","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1571,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89654,"AVALU":"g/L","BASE2":2.98845,"BASE":2.92042,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09192,"PCHG2":-3.07576,"CHG":-0.02388,"PCHG":-0.81782,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-03 22:37:43","ADY":1000,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-239","SUBJID":"id-239","SITEID":"CHN-13","AGE":58,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.44252,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-05","TRTSDTM":"2020-11-06 22:37:43","TRTEDTM":"2023-11-07 16:37:43","TRT01SDTM":"2020-11-06 22:37:43","TRT01EDTM":"2022-11-07 10:37:43","TRT02SDTM":"2022-11-07 10:37:43","TRT02EDTM":"2023-11-07 16:37:43","AP01SDTM":"2020-11-06 22:37:43","AP01EDTM":"2022-11-07 10:37:43","AP02SDTM":"2022-11-07 10:37:43","AP02EDTM":"2023-11-07 16:37:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-07","EOSDY":1096,"LSTALVDT":"2023-12-01","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6650,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.06403,"AVALU":"g/L","BASE2":2.98845,"BASE":2.92042,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07557,"PCHG2":2.52888,"CHG":0.14361,"PCHG":4.91738,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2023-09-03 22:37:43","ADY":1031,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-239","SUBJID":"id-239","SITEID":"CHN-13","AGE":58,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.44252,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-05","TRTSDTM":"2020-11-06 22:37:43","TRTEDTM":"2023-11-07 16:37:43","TRT01SDTM":"2020-11-06 22:37:43","TRT01EDTM":"2022-11-07 10:37:43","TRT02SDTM":"2022-11-07 10:37:43","TRT02EDTM":"2023-11-07 16:37:43","AP01SDTM":"2020-11-06 22:37:43","AP01EDTM":"2022-11-07 10:37:43","AP02SDTM":"2022-11-07 10:37:43","AP02EDTM":"2023-11-07 16:37:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-07","EOSDY":1096,"LSTALVDT":"2023-12-01","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1836,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00115,"AVALU":"g/L","BASE2":2.98845,"BASE":2.92042,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0127,"PCHG2":0.42484,"CHG":0.08073,"PCHG":2.76432,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2023-09-17 22:37:43","ADY":1045,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-240","SUBJID":"id-240","SITEID":"CHN-13","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.49929,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-06","TRTSDTM":"2019-04-08 12:56:28","TRTEDTM":"2022-02-15 02:29:03","TRT01SDTM":"2019-04-08 12:56:28","TRT01EDTM":"2021-02-14 20:29:03","TRT02SDTM":"2021-02-14 20:29:03","TRT02EDTM":"2022-02-15 02:29:03","AP01SDTM":"2019-04-08 12:56:28","AP01EDTM":"2021-02-14 20:29:03","AP02SDTM":"2021-02-14 20:29:03","AP02EDTM":"2022-02-15 02:29:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1044,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":43,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1086,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":267,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.89352,"AVALU":"U/L","BASE2":1.89352,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2019-07-01 12:56:28","ADY":84,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-240","SUBJID":"id-240","SITEID":"CHN-13","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.49929,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-06","TRTSDTM":"2019-04-08 12:56:28","TRTEDTM":"2022-02-15 02:29:03","TRT01SDTM":"2019-04-08 12:56:28","TRT01EDTM":"2021-02-14 20:29:03","TRT02SDTM":"2021-02-14 20:29:03","TRT02EDTM":"2022-02-15 02:29:03","AP01SDTM":"2019-04-08 12:56:28","AP01EDTM":"2021-02-14 20:29:03","AP02SDTM":"2021-02-14 20:29:03","AP02EDTM":"2022-02-15 02:29:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1044,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":43,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1086,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3233,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.45316,"AVALU":"U/L","BASE2":1.89352,"BASE":17.45316,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":15.55964,"PCHG2":821.73224,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-23 12:56:28","ADY":106,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-240","SUBJID":"id-240","SITEID":"CHN-13","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.49929,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-06","TRTSDTM":"2019-04-08 12:56:28","TRTEDTM":"2022-02-15 02:29:03","TRT01SDTM":"2019-04-08 12:56:28","TRT01EDTM":"2021-02-14 20:29:03","TRT02SDTM":"2021-02-14 20:29:03","TRT02EDTM":"2022-02-15 02:29:03","AP01SDTM":"2019-04-08 12:56:28","AP01EDTM":"2021-02-14 20:29:03","AP02SDTM":"2021-02-14 20:29:03","AP02EDTM":"2022-02-15 02:29:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1044,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":43,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1086,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7961,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.92706,"AVALU":"U/L","BASE2":1.89352,"BASE":17.45316,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":28.03354,"PCHG2":1480.50118,"CHG":12.4739,"PCHG":71.47075,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-18 12:56:28","ADY":224,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-240","SUBJID":"id-240","SITEID":"CHN-13","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.49929,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-06","TRTSDTM":"2019-04-08 12:56:28","TRTEDTM":"2022-02-15 02:29:03","TRT01SDTM":"2019-04-08 12:56:28","TRT01EDTM":"2021-02-14 20:29:03","TRT02SDTM":"2021-02-14 20:29:03","TRT02EDTM":"2022-02-15 02:29:03","AP01SDTM":"2019-04-08 12:56:28","AP01EDTM":"2021-02-14 20:29:03","AP02SDTM":"2021-02-14 20:29:03","AP02EDTM":"2022-02-15 02:29:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1044,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":43,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1086,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2499,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.55948,"AVALU":"U/L","BASE2":1.89352,"BASE":17.45316,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":23.66597,"PCHG2":1249.84176,"CHG":8.10633,"PCHG":46.44619,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-03 12:56:28","ADY":330,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-240","SUBJID":"id-240","SITEID":"CHN-13","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.49929,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-06","TRTSDTM":"2019-04-08 12:56:28","TRTEDTM":"2022-02-15 02:29:03","TRT01SDTM":"2019-04-08 12:56:28","TRT01EDTM":"2021-02-14 20:29:03","TRT02SDTM":"2021-02-14 20:29:03","TRT02EDTM":"2022-02-15 02:29:03","AP01SDTM":"2019-04-08 12:56:28","AP01EDTM":"2021-02-14 20:29:03","AP02SDTM":"2021-02-14 20:29:03","AP02EDTM":"2022-02-15 02:29:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1044,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":43,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1086,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6084,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.45623,"AVALU":"U/L","BASE2":1.89352,"BASE":17.45316,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.56271,"PCHG2":82.52947,"CHG":-13.99693,"PCHG":-80.19713,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-05-31 12:56:28","ADY":419,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-240","SUBJID":"id-240","SITEID":"CHN-13","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.49929,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-06","TRTSDTM":"2019-04-08 12:56:28","TRTEDTM":"2022-02-15 02:29:03","TRT01SDTM":"2019-04-08 12:56:28","TRT01EDTM":"2021-02-14 20:29:03","TRT02SDTM":"2021-02-14 20:29:03","TRT02EDTM":"2022-02-15 02:29:03","AP01SDTM":"2019-04-08 12:56:28","AP01EDTM":"2021-02-14 20:29:03","AP02SDTM":"2021-02-14 20:29:03","AP02EDTM":"2022-02-15 02:29:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1044,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":43,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1086,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":957,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.41985,"AVALU":"U/L","BASE2":1.89352,"BASE":17.45316,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":17.52633,"PCHG2":925.59668,"CHG":1.96669,"PCHG":11.2684,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-23 12:56:28","ADY":868,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-240","SUBJID":"id-240","SITEID":"CHN-13","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.49929,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-06","TRTSDTM":"2019-04-08 12:56:28","TRTEDTM":"2022-02-15 02:29:03","TRT01SDTM":"2019-04-08 12:56:28","TRT01EDTM":"2021-02-14 20:29:03","TRT02SDTM":"2021-02-14 20:29:03","TRT02EDTM":"2022-02-15 02:29:03","AP01SDTM":"2019-04-08 12:56:28","AP01EDTM":"2021-02-14 20:29:03","AP02SDTM":"2021-02-14 20:29:03","AP02EDTM":"2022-02-15 02:29:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1044,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":43,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1086,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":694,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.50838,"AVALU":"U/L","BASE2":1.89352,"BASE":17.45316,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":17.61487,"PCHG2":930.27244,"CHG":2.05523,"PCHG":11.77568,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-13 12:56:28","ADY":1042,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-240","SUBJID":"id-240","SITEID":"CHN-13","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.49929,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-06","TRTSDTM":"2019-04-08 12:56:28","TRTEDTM":"2022-02-15 02:29:03","TRT01SDTM":"2019-04-08 12:56:28","TRT01EDTM":"2021-02-14 20:29:03","TRT02SDTM":"2021-02-14 20:29:03","TRT02EDTM":"2022-02-15 02:29:03","AP01SDTM":"2019-04-08 12:56:28","AP01EDTM":"2021-02-14 20:29:03","AP02SDTM":"2021-02-14 20:29:03","AP02EDTM":"2022-02-15 02:29:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1044,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":43,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1086,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6866,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.97489,"AVALU":"mg/L","BASE2":8.97489,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-01 12:56:28","ADY":84,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-240","SUBJID":"id-240","SITEID":"CHN-13","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.49929,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-06","TRTSDTM":"2019-04-08 12:56:28","TRTEDTM":"2022-02-15 02:29:03","TRT01SDTM":"2019-04-08 12:56:28","TRT01EDTM":"2021-02-14 20:29:03","TRT02SDTM":"2021-02-14 20:29:03","TRT02EDTM":"2022-02-15 02:29:03","AP01SDTM":"2019-04-08 12:56:28","AP01EDTM":"2021-02-14 20:29:03","AP02SDTM":"2021-02-14 20:29:03","AP02EDTM":"2022-02-15 02:29:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1044,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":43,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1086,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7396,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.53344,"AVALU":"mg/L","BASE2":8.97489,"BASE":9.53344,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.55855,"PCHG2":6.22353,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-23 12:56:28","ADY":106,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-240","SUBJID":"id-240","SITEID":"CHN-13","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.49929,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-06","TRTSDTM":"2019-04-08 12:56:28","TRTEDTM":"2022-02-15 02:29:03","TRT01SDTM":"2019-04-08 12:56:28","TRT01EDTM":"2021-02-14 20:29:03","TRT02SDTM":"2021-02-14 20:29:03","TRT02EDTM":"2022-02-15 02:29:03","AP01SDTM":"2019-04-08 12:56:28","AP01EDTM":"2021-02-14 20:29:03","AP02SDTM":"2021-02-14 20:29:03","AP02EDTM":"2022-02-15 02:29:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1044,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":43,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1086,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6520,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.87046,"AVALU":"mg/L","BASE2":8.97489,"BASE":9.53344,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.89557,"PCHG2":9.97866,"CHG":0.33702,"PCHG":3.53512,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-18 12:56:28","ADY":224,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-240","SUBJID":"id-240","SITEID":"CHN-13","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.49929,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-06","TRTSDTM":"2019-04-08 12:56:28","TRTEDTM":"2022-02-15 02:29:03","TRT01SDTM":"2019-04-08 12:56:28","TRT01EDTM":"2021-02-14 20:29:03","TRT02SDTM":"2021-02-14 20:29:03","TRT02EDTM":"2022-02-15 02:29:03","AP01SDTM":"2019-04-08 12:56:28","AP01EDTM":"2021-02-14 20:29:03","AP02SDTM":"2021-02-14 20:29:03","AP02EDTM":"2022-02-15 02:29:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1044,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":43,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1086,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5203,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":12.72796,"AVALU":"mg/L","BASE2":8.97489,"BASE":9.53344,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.75308,"PCHG2":41.81754,"CHG":3.19452,"PCHG":33.50859,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-03-03 12:56:28","ADY":330,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-240","SUBJID":"id-240","SITEID":"CHN-13","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.49929,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-06","TRTSDTM":"2019-04-08 12:56:28","TRTEDTM":"2022-02-15 02:29:03","TRT01SDTM":"2019-04-08 12:56:28","TRT01EDTM":"2021-02-14 20:29:03","TRT02SDTM":"2021-02-14 20:29:03","TRT02EDTM":"2022-02-15 02:29:03","AP01SDTM":"2019-04-08 12:56:28","AP01EDTM":"2021-02-14 20:29:03","AP02SDTM":"2021-02-14 20:29:03","AP02EDTM":"2022-02-15 02:29:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1044,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":43,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1086,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3152,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.41324,"AVALU":"mg/L","BASE2":8.97489,"BASE":9.53344,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.43836,"PCHG2":4.88427,"CHG":-0.1202,"PCHG":-1.26079,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-31 12:56:28","ADY":419,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-240","SUBJID":"id-240","SITEID":"CHN-13","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.49929,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-06","TRTSDTM":"2019-04-08 12:56:28","TRTEDTM":"2022-02-15 02:29:03","TRT01SDTM":"2019-04-08 12:56:28","TRT01EDTM":"2021-02-14 20:29:03","TRT02SDTM":"2021-02-14 20:29:03","TRT02EDTM":"2022-02-15 02:29:03","AP01SDTM":"2019-04-08 12:56:28","AP01EDTM":"2021-02-14 20:29:03","AP02SDTM":"2021-02-14 20:29:03","AP02EDTM":"2022-02-15 02:29:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1044,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":43,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1086,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2210,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.7501,"AVALU":"mg/L","BASE2":8.97489,"BASE":9.53344,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.77522,"PCHG2":8.63761,"CHG":0.21666,"PCHG":2.27265,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-23 12:56:28","ADY":868,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-240","SUBJID":"id-240","SITEID":"CHN-13","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.49929,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-06","TRTSDTM":"2019-04-08 12:56:28","TRTEDTM":"2022-02-15 02:29:03","TRT01SDTM":"2019-04-08 12:56:28","TRT01EDTM":"2021-02-14 20:29:03","TRT02SDTM":"2021-02-14 20:29:03","TRT02EDTM":"2022-02-15 02:29:03","AP01SDTM":"2019-04-08 12:56:28","AP01EDTM":"2021-02-14 20:29:03","AP02SDTM":"2021-02-14 20:29:03","AP02EDTM":"2022-02-15 02:29:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1044,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":43,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1086,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2625,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.3102,"AVALU":"mg/L","BASE2":8.97489,"BASE":9.53344,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.33532,"PCHG2":14.8784,"CHG":0.77676,"PCHG":8.14779,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-02-13 12:56:28","ADY":1042,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-240","SUBJID":"id-240","SITEID":"CHN-13","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.49929,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-06","TRTSDTM":"2019-04-08 12:56:28","TRTEDTM":"2022-02-15 02:29:03","TRT01SDTM":"2019-04-08 12:56:28","TRT01EDTM":"2021-02-14 20:29:03","TRT02SDTM":"2021-02-14 20:29:03","TRT02EDTM":"2022-02-15 02:29:03","AP01SDTM":"2019-04-08 12:56:28","AP01EDTM":"2021-02-14 20:29:03","AP02SDTM":"2021-02-14 20:29:03","AP02EDTM":"2022-02-15 02:29:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1044,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":43,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1086,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":145,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98023,"AVALU":"g/L","BASE2":2.98023,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-01 12:56:28","ADY":84,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-240","SUBJID":"id-240","SITEID":"CHN-13","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.49929,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-06","TRTSDTM":"2019-04-08 12:56:28","TRTEDTM":"2022-02-15 02:29:03","TRT01SDTM":"2019-04-08 12:56:28","TRT01EDTM":"2021-02-14 20:29:03","TRT02SDTM":"2021-02-14 20:29:03","TRT02EDTM":"2022-02-15 02:29:03","AP01SDTM":"2019-04-08 12:56:28","AP01EDTM":"2021-02-14 20:29:03","AP02SDTM":"2021-02-14 20:29:03","AP02EDTM":"2022-02-15 02:29:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1044,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":43,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1086,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1298,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88784,"AVALU":"g/L","BASE2":2.98023,"BASE":2.88784,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.09239,"PCHG2":-3.10009,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-23 12:56:28","ADY":106,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-240","SUBJID":"id-240","SITEID":"CHN-13","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.49929,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-06","TRTSDTM":"2019-04-08 12:56:28","TRTEDTM":"2022-02-15 02:29:03","TRT01SDTM":"2019-04-08 12:56:28","TRT01EDTM":"2021-02-14 20:29:03","TRT02SDTM":"2021-02-14 20:29:03","TRT02EDTM":"2022-02-15 02:29:03","AP01SDTM":"2019-04-08 12:56:28","AP01EDTM":"2021-02-14 20:29:03","AP02SDTM":"2021-02-14 20:29:03","AP02EDTM":"2022-02-15 02:29:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1044,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":43,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1086,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":25,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.16089,"AVALU":"g/L","BASE2":2.98023,"BASE":2.88784,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18066,"PCHG2":6.06199,"CHG":0.27305,"PCHG":9.45519,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2019-11-18 12:56:28","ADY":224,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-240","SUBJID":"id-240","SITEID":"CHN-13","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.49929,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-06","TRTSDTM":"2019-04-08 12:56:28","TRTEDTM":"2022-02-15 02:29:03","TRT01SDTM":"2019-04-08 12:56:28","TRT01EDTM":"2021-02-14 20:29:03","TRT02SDTM":"2021-02-14 20:29:03","TRT02EDTM":"2022-02-15 02:29:03","AP01SDTM":"2019-04-08 12:56:28","AP01EDTM":"2021-02-14 20:29:03","AP02SDTM":"2021-02-14 20:29:03","AP02EDTM":"2022-02-15 02:29:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1044,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":43,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1086,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":496,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00005,"AVALU":"g/L","BASE2":2.98023,"BASE":2.88784,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01982,"PCHG2":0.66491,"CHG":0.11221,"PCHG":3.88546,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-03-03 12:56:28","ADY":330,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-240","SUBJID":"id-240","SITEID":"CHN-13","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.49929,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-06","TRTSDTM":"2019-04-08 12:56:28","TRTEDTM":"2022-02-15 02:29:03","TRT01SDTM":"2019-04-08 12:56:28","TRT01EDTM":"2021-02-14 20:29:03","TRT02SDTM":"2021-02-14 20:29:03","TRT02EDTM":"2022-02-15 02:29:03","AP01SDTM":"2019-04-08 12:56:28","AP01EDTM":"2021-02-14 20:29:03","AP02SDTM":"2021-02-14 20:29:03","AP02EDTM":"2022-02-15 02:29:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1044,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":43,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1086,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5072,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91625,"AVALU":"g/L","BASE2":2.98023,"BASE":2.88784,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06399,"PCHG2":-2.14707,"CHG":0.0284,"PCHG":0.98351,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-31 12:56:28","ADY":419,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-240","SUBJID":"id-240","SITEID":"CHN-13","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.49929,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-06","TRTSDTM":"2019-04-08 12:56:28","TRTEDTM":"2022-02-15 02:29:03","TRT01SDTM":"2019-04-08 12:56:28","TRT01EDTM":"2021-02-14 20:29:03","TRT02SDTM":"2021-02-14 20:29:03","TRT02EDTM":"2022-02-15 02:29:03","AP01SDTM":"2019-04-08 12:56:28","AP01EDTM":"2021-02-14 20:29:03","AP02SDTM":"2021-02-14 20:29:03","AP02EDTM":"2022-02-15 02:29:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1044,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":43,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1086,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6791,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.876,"AVALU":"g/L","BASE2":2.98023,"BASE":2.88784,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10423,"PCHG2":-3.49754,"CHG":-0.01184,"PCHG":-0.41017,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-23 12:56:28","ADY":868,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-240","SUBJID":"id-240","SITEID":"CHN-13","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.49929,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-06","TRTSDTM":"2019-04-08 12:56:28","TRTEDTM":"2022-02-15 02:29:03","TRT01SDTM":"2019-04-08 12:56:28","TRT01EDTM":"2021-02-14 20:29:03","TRT02SDTM":"2021-02-14 20:29:03","TRT02EDTM":"2022-02-15 02:29:03","AP01SDTM":"2019-04-08 12:56:28","AP01EDTM":"2021-02-14 20:29:03","AP02SDTM":"2021-02-14 20:29:03","AP02EDTM":"2022-02-15 02:29:03","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1044,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":43,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1086,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7876,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95892,"AVALU":"g/L","BASE2":2.98023,"BASE":2.88784,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02131,"PCHG2":-0.71502,"CHG":0.07108,"PCHG":2.46137,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-13 12:56:28","ADY":1042,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-249","SUBJID":"id-249","SITEID":"CHN-13","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78004,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-25 05:30:37","TRTEDTM":"2022-02-12 21:27:18","TRT01SDTM":"2020-02-25 05:30:37","TRT01EDTM":"2021-02-12 15:27:18","TRT02SDTM":"2021-02-12 15:27:18","TRT02EDTM":"2022-02-12 21:27:18","AP01SDTM":"2020-02-25 05:30:37","AP01EDTM":"2021-02-12 15:27:18","AP02SDTM":"2021-02-12 15:27:18","AP02EDTM":"2022-02-12 21:27:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":719,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-10","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":132,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.85236,"AVALU":"U/L","BASE2":4.85236,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-03-16 05:30:37","ADY":20,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-249","SUBJID":"id-249","SITEID":"CHN-13","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78004,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-25 05:30:37","TRTEDTM":"2022-02-12 21:27:18","TRT01SDTM":"2020-02-25 05:30:37","TRT01EDTM":"2021-02-12 15:27:18","TRT02SDTM":"2021-02-12 15:27:18","TRT02EDTM":"2022-02-12 21:27:18","AP01SDTM":"2020-02-25 05:30:37","AP01EDTM":"2021-02-12 15:27:18","AP02SDTM":"2021-02-12 15:27:18","AP02EDTM":"2022-02-12 21:27:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":719,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-10","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4115,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.23596,"AVALU":"U/L","BASE2":4.85236,"BASE":12.23596,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":7.3836,"PCHG2":152.16532,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-07 05:30:37","ADY":42,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-249","SUBJID":"id-249","SITEID":"CHN-13","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78004,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-25 05:30:37","TRTEDTM":"2022-02-12 21:27:18","TRT01SDTM":"2020-02-25 05:30:37","TRT01EDTM":"2021-02-12 15:27:18","TRT02SDTM":"2021-02-12 15:27:18","TRT02EDTM":"2022-02-12 21:27:18","AP01SDTM":"2020-02-25 05:30:37","AP01EDTM":"2021-02-12 15:27:18","AP02SDTM":"2021-02-12 15:27:18","AP02EDTM":"2022-02-12 21:27:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":719,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-10","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6900,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.52857,"AVALU":"U/L","BASE2":4.85236,"BASE":12.23596,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":28.67622,"PCHG2":590.97523,"CHG":21.29262,"PCHG":174.01675,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-05 05:30:37","ADY":223,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-249","SUBJID":"id-249","SITEID":"CHN-13","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78004,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-25 05:30:37","TRTEDTM":"2022-02-12 21:27:18","TRT01SDTM":"2020-02-25 05:30:37","TRT01EDTM":"2021-02-12 15:27:18","TRT02SDTM":"2021-02-12 15:27:18","TRT02EDTM":"2022-02-12 21:27:18","AP01SDTM":"2020-02-25 05:30:37","AP01EDTM":"2021-02-12 15:27:18","AP02SDTM":"2021-02-12 15:27:18","AP02EDTM":"2022-02-12 21:27:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":719,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-10","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":462,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.99421,"AVALU":"U/L","BASE2":4.85236,"BASE":12.23596,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.14186,"PCHG2":105.96625,"CHG":-2.24174,"PCHG":-18.32095,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-29 05:30:37","ADY":339,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-249","SUBJID":"id-249","SITEID":"CHN-13","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78004,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-25 05:30:37","TRTEDTM":"2022-02-12 21:27:18","TRT01SDTM":"2020-02-25 05:30:37","TRT01EDTM":"2021-02-12 15:27:18","TRT02SDTM":"2021-02-12 15:27:18","TRT02EDTM":"2022-02-12 21:27:18","AP01SDTM":"2020-02-25 05:30:37","AP01EDTM":"2021-02-12 15:27:18","AP02SDTM":"2021-02-12 15:27:18","AP02EDTM":"2022-02-12 21:27:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":719,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-10","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":14,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.17655,"AVALU":"U/L","BASE2":4.85236,"BASE":12.23596,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":24.32419,"PCHG2":501.28625,"CHG":16.94059,"PCHG":138.44922,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-04 05:30:37","ADY":373,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-249","SUBJID":"id-249","SITEID":"CHN-13","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78004,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-25 05:30:37","TRTEDTM":"2022-02-12 21:27:18","TRT01SDTM":"2020-02-25 05:30:37","TRT01EDTM":"2021-02-12 15:27:18","TRT02SDTM":"2021-02-12 15:27:18","TRT02EDTM":"2022-02-12 21:27:18","AP01SDTM":"2020-02-25 05:30:37","AP01EDTM":"2021-02-12 15:27:18","AP02SDTM":"2021-02-12 15:27:18","AP02EDTM":"2022-02-12 21:27:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":719,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-10","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8079,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.0969,"AVALU":"U/L","BASE2":4.85236,"BASE":12.23596,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.24454,"PCHG2":293.55929,"CHG":6.86094,"PCHG":56.07193,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-15 05:30:37","ADY":659,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-249","SUBJID":"id-249","SITEID":"CHN-13","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78004,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-25 05:30:37","TRTEDTM":"2022-02-12 21:27:18","TRT01SDTM":"2020-02-25 05:30:37","TRT01EDTM":"2021-02-12 15:27:18","TRT02SDTM":"2021-02-12 15:27:18","TRT02EDTM":"2022-02-12 21:27:18","AP01SDTM":"2020-02-25 05:30:37","AP01EDTM":"2021-02-12 15:27:18","AP02SDTM":"2021-02-12 15:27:18","AP02EDTM":"2022-02-12 21:27:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":719,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-10","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":812,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.59448,"AVALU":"U/L","BASE2":4.85236,"BASE":12.23596,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":21.74212,"PCHG2":448.07355,"CHG":14.35852,"PCHG":117.34691,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-08 05:30:37","ADY":683,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-249","SUBJID":"id-249","SITEID":"CHN-13","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78004,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-25 05:30:37","TRTEDTM":"2022-02-12 21:27:18","TRT01SDTM":"2020-02-25 05:30:37","TRT01EDTM":"2021-02-12 15:27:18","TRT02SDTM":"2021-02-12 15:27:18","TRT02EDTM":"2022-02-12 21:27:18","AP01SDTM":"2020-02-25 05:30:37","AP01EDTM":"2021-02-12 15:27:18","AP02SDTM":"2021-02-12 15:27:18","AP02EDTM":"2022-02-12 21:27:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":719,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-10","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3447,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.67342,"AVALU":"mg/L","BASE2":9.67342,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-16 05:30:37","ADY":20,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-249","SUBJID":"id-249","SITEID":"CHN-13","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78004,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-25 05:30:37","TRTEDTM":"2022-02-12 21:27:18","TRT01SDTM":"2020-02-25 05:30:37","TRT01EDTM":"2021-02-12 15:27:18","TRT02SDTM":"2021-02-12 15:27:18","TRT02EDTM":"2022-02-12 21:27:18","AP01SDTM":"2020-02-25 05:30:37","AP01EDTM":"2021-02-12 15:27:18","AP02SDTM":"2021-02-12 15:27:18","AP02EDTM":"2022-02-12 21:27:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":719,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-10","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6107,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.99609,"AVALU":"mg/L","BASE2":9.67342,"BASE":9.99609,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.32266,"PCHG2":3.33557,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-07 05:30:37","ADY":42,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-249","SUBJID":"id-249","SITEID":"CHN-13","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78004,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-25 05:30:37","TRTEDTM":"2022-02-12 21:27:18","TRT01SDTM":"2020-02-25 05:30:37","TRT01EDTM":"2021-02-12 15:27:18","TRT02SDTM":"2021-02-12 15:27:18","TRT02EDTM":"2022-02-12 21:27:18","AP01SDTM":"2020-02-25 05:30:37","AP01EDTM":"2021-02-12 15:27:18","AP02SDTM":"2021-02-12 15:27:18","AP02EDTM":"2022-02-12 21:27:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":719,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-10","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8110,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.78244,"AVALU":"mg/L","BASE2":9.67342,"BASE":9.99609,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.89099,"PCHG2":-9.21065,"CHG":-1.21365,"PCHG":-12.14124,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-05 05:30:37","ADY":223,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-249","SUBJID":"id-249","SITEID":"CHN-13","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78004,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-25 05:30:37","TRTEDTM":"2022-02-12 21:27:18","TRT01SDTM":"2020-02-25 05:30:37","TRT01EDTM":"2021-02-12 15:27:18","TRT02SDTM":"2021-02-12 15:27:18","TRT02EDTM":"2022-02-12 21:27:18","AP01SDTM":"2020-02-25 05:30:37","AP01EDTM":"2021-02-12 15:27:18","AP02SDTM":"2021-02-12 15:27:18","AP02EDTM":"2022-02-12 21:27:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":719,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-10","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2833,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.43148,"AVALU":"mg/L","BASE2":9.67342,"BASE":9.99609,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.24195,"PCHG2":-12.83875,"CHG":-1.56461,"PCHG":-15.65223,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-29 05:30:37","ADY":339,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-249","SUBJID":"id-249","SITEID":"CHN-13","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78004,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-25 05:30:37","TRTEDTM":"2022-02-12 21:27:18","TRT01SDTM":"2020-02-25 05:30:37","TRT01EDTM":"2021-02-12 15:27:18","TRT02SDTM":"2021-02-12 15:27:18","TRT02EDTM":"2022-02-12 21:27:18","AP01SDTM":"2020-02-25 05:30:37","AP01EDTM":"2021-02-12 15:27:18","AP02SDTM":"2021-02-12 15:27:18","AP02EDTM":"2022-02-12 21:27:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":719,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-10","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3743,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.37251,"AVALU":"mg/L","BASE2":9.67342,"BASE":9.99609,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.30091,"PCHG2":-3.11067,"CHG":-0.62357,"PCHG":-6.23816,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-04 05:30:37","ADY":373,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-249","SUBJID":"id-249","SITEID":"CHN-13","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78004,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-25 05:30:37","TRTEDTM":"2022-02-12 21:27:18","TRT01SDTM":"2020-02-25 05:30:37","TRT01EDTM":"2021-02-12 15:27:18","TRT02SDTM":"2021-02-12 15:27:18","TRT02EDTM":"2022-02-12 21:27:18","AP01SDTM":"2020-02-25 05:30:37","AP01EDTM":"2021-02-12 15:27:18","AP02SDTM":"2021-02-12 15:27:18","AP02EDTM":"2022-02-12 21:27:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":719,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-10","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2885,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.2092,"AVALU":"mg/L","BASE2":9.67342,"BASE":9.99609,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.46422,"PCHG2":-15.13656,"CHG":-1.78689,"PCHG":-17.87586,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-15 05:30:37","ADY":659,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-249","SUBJID":"id-249","SITEID":"CHN-13","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78004,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-25 05:30:37","TRTEDTM":"2022-02-12 21:27:18","TRT01SDTM":"2020-02-25 05:30:37","TRT01EDTM":"2021-02-12 15:27:18","TRT02SDTM":"2021-02-12 15:27:18","TRT02EDTM":"2022-02-12 21:27:18","AP01SDTM":"2020-02-25 05:30:37","AP01EDTM":"2021-02-12 15:27:18","AP02SDTM":"2021-02-12 15:27:18","AP02EDTM":"2022-02-12 21:27:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":719,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-10","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2640,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.19978,"AVALU":"mg/L","BASE2":9.67342,"BASE":9.99609,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.47364,"PCHG2":-4.89632,"CHG":-0.7963,"PCHG":-7.96617,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-08 05:30:37","ADY":683,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-249","SUBJID":"id-249","SITEID":"CHN-13","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78004,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-25 05:30:37","TRTEDTM":"2022-02-12 21:27:18","TRT01SDTM":"2020-02-25 05:30:37","TRT01EDTM":"2021-02-12 15:27:18","TRT02SDTM":"2021-02-12 15:27:18","TRT02EDTM":"2022-02-12 21:27:18","AP01SDTM":"2020-02-25 05:30:37","AP01EDTM":"2021-02-12 15:27:18","AP02SDTM":"2021-02-12 15:27:18","AP02EDTM":"2022-02-12 21:27:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":719,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-10","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7566,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84553,"AVALU":"g/L","BASE2":2.84553,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-16 05:30:37","ADY":20,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-249","SUBJID":"id-249","SITEID":"CHN-13","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78004,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-25 05:30:37","TRTEDTM":"2022-02-12 21:27:18","TRT01SDTM":"2020-02-25 05:30:37","TRT01EDTM":"2021-02-12 15:27:18","TRT02SDTM":"2021-02-12 15:27:18","TRT02EDTM":"2022-02-12 21:27:18","AP01SDTM":"2020-02-25 05:30:37","AP01EDTM":"2021-02-12 15:27:18","AP02SDTM":"2021-02-12 15:27:18","AP02EDTM":"2022-02-12 21:27:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":719,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-10","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7298,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89705,"AVALU":"g/L","BASE2":2.84553,"BASE":2.89705,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.05153,"PCHG2":1.81074,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-07 05:30:37","ADY":42,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-249","SUBJID":"id-249","SITEID":"CHN-13","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78004,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-25 05:30:37","TRTEDTM":"2022-02-12 21:27:18","TRT01SDTM":"2020-02-25 05:30:37","TRT01EDTM":"2021-02-12 15:27:18","TRT02SDTM":"2021-02-12 15:27:18","TRT02EDTM":"2022-02-12 21:27:18","AP01SDTM":"2020-02-25 05:30:37","AP01EDTM":"2021-02-12 15:27:18","AP02SDTM":"2021-02-12 15:27:18","AP02EDTM":"2022-02-12 21:27:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":719,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-10","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6033,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85973,"AVALU":"g/L","BASE2":2.84553,"BASE":2.89705,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0142,"PCHG2":0.4992,"CHG":-0.03732,"PCHG":-1.28821,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-05 05:30:37","ADY":223,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-249","SUBJID":"id-249","SITEID":"CHN-13","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78004,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-25 05:30:37","TRTEDTM":"2022-02-12 21:27:18","TRT01SDTM":"2020-02-25 05:30:37","TRT01EDTM":"2021-02-12 15:27:18","TRT02SDTM":"2021-02-12 15:27:18","TRT02EDTM":"2022-02-12 21:27:18","AP01SDTM":"2020-02-25 05:30:37","AP01EDTM":"2021-02-12 15:27:18","AP02SDTM":"2021-02-12 15:27:18","AP02EDTM":"2022-02-12 21:27:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":719,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-10","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3536,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92781,"AVALU":"g/L","BASE2":2.84553,"BASE":2.89705,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08228,"PCHG2":2.89161,"CHG":0.03076,"PCHG":1.06164,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-29 05:30:37","ADY":339,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-249","SUBJID":"id-249","SITEID":"CHN-13","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78004,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-25 05:30:37","TRTEDTM":"2022-02-12 21:27:18","TRT01SDTM":"2020-02-25 05:30:37","TRT01EDTM":"2021-02-12 15:27:18","TRT02SDTM":"2021-02-12 15:27:18","TRT02EDTM":"2022-02-12 21:27:18","AP01SDTM":"2020-02-25 05:30:37","AP01EDTM":"2021-02-12 15:27:18","AP02SDTM":"2021-02-12 15:27:18","AP02EDTM":"2022-02-12 21:27:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":719,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-10","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6145,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86015,"AVALU":"g/L","BASE2":2.84553,"BASE":2.89705,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01463,"PCHG2":0.51405,"CHG":-0.0369,"PCHG":-1.27363,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-04 05:30:37","ADY":373,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-249","SUBJID":"id-249","SITEID":"CHN-13","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78004,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-25 05:30:37","TRTEDTM":"2022-02-12 21:27:18","TRT01SDTM":"2020-02-25 05:30:37","TRT01EDTM":"2021-02-12 15:27:18","TRT02SDTM":"2021-02-12 15:27:18","TRT02EDTM":"2022-02-12 21:27:18","AP01SDTM":"2020-02-25 05:30:37","AP01EDTM":"2021-02-12 15:27:18","AP02SDTM":"2021-02-12 15:27:18","AP02EDTM":"2022-02-12 21:27:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":719,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-10","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6518,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88045,"AVALU":"g/L","BASE2":2.84553,"BASE":2.89705,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03493,"PCHG2":1.22744,"CHG":-0.0166,"PCHG":-0.57293,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-15 05:30:37","ADY":659,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-249","SUBJID":"id-249","SITEID":"CHN-13","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.78004,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-24","TRTSDTM":"2020-02-25 05:30:37","TRTEDTM":"2022-02-12 21:27:18","TRT01SDTM":"2020-02-25 05:30:37","TRT01EDTM":"2021-02-12 15:27:18","TRT02SDTM":"2021-02-12 15:27:18","TRT02EDTM":"2022-02-12 21:27:18","AP01SDTM":"2020-02-25 05:30:37","AP01EDTM":"2021-02-12 15:27:18","AP02SDTM":"2021-02-12 15:27:18","AP02EDTM":"2022-02-12 21:27:18","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":719,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-10","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8143,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97441,"AVALU":"g/L","BASE2":2.84553,"BASE":2.89705,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12888,"PCHG2":4.52936,"CHG":0.07736,"PCHG":2.67026,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-08 05:30:37","ADY":683,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-270","SUBJID":"id-270","SITEID":"CHN-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":15.11156,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-13","TRTSDTM":"2019-08-17 15:09:21","TRTEDTM":"2022-08-17 09:09:21","TRT01SDTM":"2019-08-17 15:09:21","TRT01EDTM":"2021-08-17 03:09:21","TRT02SDTM":"2021-08-17 03:09:21","TRT02EDTM":"2022-08-17 09:09:21","AP01SDTM":"2019-08-17 15:09:21","AP01EDTM":"2021-08-17 03:09:21","AP02SDTM":"2021-08-17 03:09:21","AP02EDTM":"2022-08-17 09:09:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-17","EOSDY":1096,"LSTALVDT":"2022-09-02","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4973,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.76433,"AVALU":"U/L","BASE2":2.76433,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2019-09-29 15:09:21","ADY":43,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-270","SUBJID":"id-270","SITEID":"CHN-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":15.11156,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-13","TRTSDTM":"2019-08-17 15:09:21","TRTEDTM":"2022-08-17 09:09:21","TRT01SDTM":"2019-08-17 15:09:21","TRT01EDTM":"2021-08-17 03:09:21","TRT02SDTM":"2021-08-17 03:09:21","TRT02EDTM":"2022-08-17 09:09:21","AP01SDTM":"2019-08-17 15:09:21","AP01EDTM":"2021-08-17 03:09:21","AP02SDTM":"2021-08-17 03:09:21","AP02EDTM":"2022-08-17 09:09:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-17","EOSDY":1096,"LSTALVDT":"2022-09-02","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8361,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":38.89773,"AVALU":"U/L","BASE2":2.76433,"BASE":38.89773,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":36.1334,"PCHG2":1307.12945,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-28 15:09:21","ADY":316,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-270","SUBJID":"id-270","SITEID":"CHN-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":15.11156,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-13","TRTSDTM":"2019-08-17 15:09:21","TRTEDTM":"2022-08-17 09:09:21","TRT01SDTM":"2019-08-17 15:09:21","TRT01EDTM":"2021-08-17 03:09:21","TRT02SDTM":"2021-08-17 03:09:21","TRT02EDTM":"2022-08-17 09:09:21","AP01SDTM":"2019-08-17 15:09:21","AP01EDTM":"2021-08-17 03:09:21","AP02SDTM":"2021-08-17 03:09:21","AP02EDTM":"2022-08-17 09:09:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-17","EOSDY":1096,"LSTALVDT":"2022-09-02","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7749,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.99126,"AVALU":"U/L","BASE2":2.76433,"BASE":38.89773,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":30.22693,"PCHG2":1093.46219,"CHG":-5.90647,"PCHG":-15.18462,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-10 15:09:21","ADY":390,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-270","SUBJID":"id-270","SITEID":"CHN-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":15.11156,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-13","TRTSDTM":"2019-08-17 15:09:21","TRTEDTM":"2022-08-17 09:09:21","TRT01SDTM":"2019-08-17 15:09:21","TRT01EDTM":"2021-08-17 03:09:21","TRT02SDTM":"2021-08-17 03:09:21","TRT02EDTM":"2022-08-17 09:09:21","AP01SDTM":"2019-08-17 15:09:21","AP01EDTM":"2021-08-17 03:09:21","AP02SDTM":"2021-08-17 03:09:21","AP02EDTM":"2022-08-17 09:09:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-17","EOSDY":1096,"LSTALVDT":"2022-09-02","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":594,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.93862,"AVALU":"U/L","BASE2":2.76433,"BASE":38.89773,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.17429,"PCHG2":223.35547,"CHG":-29.95911,"PCHG":-77.0202,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-19 15:09:21","ADY":490,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-270","SUBJID":"id-270","SITEID":"CHN-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":15.11156,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-13","TRTSDTM":"2019-08-17 15:09:21","TRTEDTM":"2022-08-17 09:09:21","TRT01SDTM":"2019-08-17 15:09:21","TRT01EDTM":"2021-08-17 03:09:21","TRT02SDTM":"2021-08-17 03:09:21","TRT02EDTM":"2022-08-17 09:09:21","AP01SDTM":"2019-08-17 15:09:21","AP01EDTM":"2021-08-17 03:09:21","AP02SDTM":"2021-08-17 03:09:21","AP02EDTM":"2022-08-17 09:09:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-17","EOSDY":1096,"LSTALVDT":"2022-09-02","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1932,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.34795,"AVALU":"U/L","BASE2":2.76433,"BASE":38.89773,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.58361,"PCHG2":419.03845,"CHG":-24.54978,"PCHG":-63.11367,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-09 15:09:21","ADY":815,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-270","SUBJID":"id-270","SITEID":"CHN-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":15.11156,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-13","TRTSDTM":"2019-08-17 15:09:21","TRTEDTM":"2022-08-17 09:09:21","TRT01SDTM":"2019-08-17 15:09:21","TRT01EDTM":"2021-08-17 03:09:21","TRT02SDTM":"2021-08-17 03:09:21","TRT02EDTM":"2022-08-17 09:09:21","AP01SDTM":"2019-08-17 15:09:21","AP01EDTM":"2021-08-17 03:09:21","AP02SDTM":"2021-08-17 03:09:21","AP02EDTM":"2022-08-17 09:09:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-17","EOSDY":1096,"LSTALVDT":"2022-09-02","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3494,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.35511,"AVALU":"U/L","BASE2":2.76433,"BASE":38.89773,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.59078,"PCHG2":310.77226,"CHG":-27.54262,"PCHG":-70.80778,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-10 15:09:21","ADY":936,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-270","SUBJID":"id-270","SITEID":"CHN-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":15.11156,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-13","TRTSDTM":"2019-08-17 15:09:21","TRTEDTM":"2022-08-17 09:09:21","TRT01SDTM":"2019-08-17 15:09:21","TRT01EDTM":"2021-08-17 03:09:21","TRT02SDTM":"2021-08-17 03:09:21","TRT02EDTM":"2022-08-17 09:09:21","AP01SDTM":"2019-08-17 15:09:21","AP01EDTM":"2021-08-17 03:09:21","AP02SDTM":"2021-08-17 03:09:21","AP02EDTM":"2022-08-17 09:09:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-17","EOSDY":1096,"LSTALVDT":"2022-09-02","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7155,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.29707,"AVALU":"U/L","BASE2":2.76433,"BASE":38.89773,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.53274,"PCHG2":19.272,"CHG":-35.60066,"PCHG":-91.52374,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-08-14 15:09:21","ADY":1093,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-270","SUBJID":"id-270","SITEID":"CHN-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":15.11156,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-13","TRTSDTM":"2019-08-17 15:09:21","TRTEDTM":"2022-08-17 09:09:21","TRT01SDTM":"2019-08-17 15:09:21","TRT01EDTM":"2021-08-17 03:09:21","TRT02SDTM":"2021-08-17 03:09:21","TRT02EDTM":"2022-08-17 09:09:21","AP01SDTM":"2019-08-17 15:09:21","AP01EDTM":"2021-08-17 03:09:21","AP02SDTM":"2021-08-17 03:09:21","AP02EDTM":"2022-08-17 09:09:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-17","EOSDY":1096,"LSTALVDT":"2022-09-02","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7093,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.59881,"AVALU":"mg/L","BASE2":7.59881,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2019-09-29 15:09:21","ADY":43,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-270","SUBJID":"id-270","SITEID":"CHN-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":15.11156,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-13","TRTSDTM":"2019-08-17 15:09:21","TRTEDTM":"2022-08-17 09:09:21","TRT01SDTM":"2019-08-17 15:09:21","TRT01EDTM":"2021-08-17 03:09:21","TRT02SDTM":"2021-08-17 03:09:21","TRT02EDTM":"2022-08-17 09:09:21","AP01SDTM":"2019-08-17 15:09:21","AP01EDTM":"2021-08-17 03:09:21","AP02SDTM":"2021-08-17 03:09:21","AP02EDTM":"2022-08-17 09:09:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-17","EOSDY":1096,"LSTALVDT":"2022-09-02","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5926,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.08907,"AVALU":"mg/L","BASE2":7.59881,"BASE":8.08907,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.49027,"PCHG2":6.45191,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-28 15:09:21","ADY":316,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-270","SUBJID":"id-270","SITEID":"CHN-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":15.11156,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-13","TRTSDTM":"2019-08-17 15:09:21","TRTEDTM":"2022-08-17 09:09:21","TRT01SDTM":"2019-08-17 15:09:21","TRT01EDTM":"2021-08-17 03:09:21","TRT02SDTM":"2021-08-17 03:09:21","TRT02EDTM":"2022-08-17 09:09:21","AP01SDTM":"2019-08-17 15:09:21","AP01EDTM":"2021-08-17 03:09:21","AP02SDTM":"2021-08-17 03:09:21","AP02EDTM":"2022-08-17 09:09:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-17","EOSDY":1096,"LSTALVDT":"2022-09-02","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6997,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.73553,"AVALU":"mg/L","BASE2":7.59881,"BASE":8.08907,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.13673,"PCHG2":14.95926,"CHG":0.64646,"PCHG":7.99173,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-10 15:09:21","ADY":390,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-270","SUBJID":"id-270","SITEID":"CHN-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":15.11156,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-13","TRTSDTM":"2019-08-17 15:09:21","TRTEDTM":"2022-08-17 09:09:21","TRT01SDTM":"2019-08-17 15:09:21","TRT01EDTM":"2021-08-17 03:09:21","TRT02SDTM":"2021-08-17 03:09:21","TRT02EDTM":"2022-08-17 09:09:21","AP01SDTM":"2019-08-17 15:09:21","AP01EDTM":"2021-08-17 03:09:21","AP02SDTM":"2021-08-17 03:09:21","AP02EDTM":"2022-08-17 09:09:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-17","EOSDY":1096,"LSTALVDT":"2022-09-02","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6820,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.94517,"AVALU":"mg/L","BASE2":7.59881,"BASE":8.08907,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.34636,"PCHG2":4.55809,"CHG":-0.14391,"PCHG":-1.77904,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-12-19 15:09:21","ADY":490,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-270","SUBJID":"id-270","SITEID":"CHN-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":15.11156,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-13","TRTSDTM":"2019-08-17 15:09:21","TRTEDTM":"2022-08-17 09:09:21","TRT01SDTM":"2019-08-17 15:09:21","TRT01EDTM":"2021-08-17 03:09:21","TRT02SDTM":"2021-08-17 03:09:21","TRT02EDTM":"2022-08-17 09:09:21","AP01SDTM":"2019-08-17 15:09:21","AP01EDTM":"2021-08-17 03:09:21","AP02SDTM":"2021-08-17 03:09:21","AP02EDTM":"2022-08-17 09:09:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-17","EOSDY":1096,"LSTALVDT":"2022-09-02","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7296,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.28781,"AVALU":"mg/L","BASE2":7.59881,"BASE":8.08907,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.68901,"PCHG2":35.38724,"CHG":2.19874,"PCHG":27.1816,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-11-09 15:09:21","ADY":815,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-270","SUBJID":"id-270","SITEID":"CHN-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":15.11156,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-13","TRTSDTM":"2019-08-17 15:09:21","TRTEDTM":"2022-08-17 09:09:21","TRT01SDTM":"2019-08-17 15:09:21","TRT01EDTM":"2021-08-17 03:09:21","TRT02SDTM":"2021-08-17 03:09:21","TRT02EDTM":"2022-08-17 09:09:21","AP01SDTM":"2019-08-17 15:09:21","AP01EDTM":"2021-08-17 03:09:21","AP02SDTM":"2021-08-17 03:09:21","AP02EDTM":"2022-08-17 09:09:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-17","EOSDY":1096,"LSTALVDT":"2022-09-02","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6125,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.51188,"AVALU":"mg/L","BASE2":7.59881,"BASE":8.08907,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.91307,"PCHG2":25.17596,"CHG":1.4228,"PCHG":17.58921,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-10 15:09:21","ADY":936,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-270","SUBJID":"id-270","SITEID":"CHN-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":15.11156,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-13","TRTSDTM":"2019-08-17 15:09:21","TRTEDTM":"2022-08-17 09:09:21","TRT01SDTM":"2019-08-17 15:09:21","TRT01EDTM":"2021-08-17 03:09:21","TRT02SDTM":"2021-08-17 03:09:21","TRT02EDTM":"2022-08-17 09:09:21","AP01SDTM":"2019-08-17 15:09:21","AP01EDTM":"2021-08-17 03:09:21","AP02SDTM":"2021-08-17 03:09:21","AP02EDTM":"2022-08-17 09:09:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-17","EOSDY":1096,"LSTALVDT":"2022-09-02","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3883,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.1098,"AVALU":"mg/L","BASE2":7.59881,"BASE":8.08907,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.511,"PCHG2":6.72473,"CHG":0.02073,"PCHG":0.25628,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-14 15:09:21","ADY":1093,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-270","SUBJID":"id-270","SITEID":"CHN-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":15.11156,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-13","TRTSDTM":"2019-08-17 15:09:21","TRTEDTM":"2022-08-17 09:09:21","TRT01SDTM":"2019-08-17 15:09:21","TRT01EDTM":"2021-08-17 03:09:21","TRT02SDTM":"2021-08-17 03:09:21","TRT02EDTM":"2022-08-17 09:09:21","AP01SDTM":"2019-08-17 15:09:21","AP01EDTM":"2021-08-17 03:09:21","AP02SDTM":"2021-08-17 03:09:21","AP02EDTM":"2022-08-17 09:09:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-17","EOSDY":1096,"LSTALVDT":"2022-09-02","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1680,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91435,"AVALU":"g/L","BASE2":2.91435,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-29 15:09:21","ADY":43,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-270","SUBJID":"id-270","SITEID":"CHN-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":15.11156,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-13","TRTSDTM":"2019-08-17 15:09:21","TRTEDTM":"2022-08-17 09:09:21","TRT01SDTM":"2019-08-17 15:09:21","TRT01EDTM":"2021-08-17 03:09:21","TRT02SDTM":"2021-08-17 03:09:21","TRT02EDTM":"2022-08-17 09:09:21","AP01SDTM":"2019-08-17 15:09:21","AP01EDTM":"2021-08-17 03:09:21","AP02SDTM":"2021-08-17 03:09:21","AP02EDTM":"2022-08-17 09:09:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-17","EOSDY":1096,"LSTALVDT":"2022-09-02","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8104,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93532,"AVALU":"g/L","BASE2":2.91435,"BASE":2.93532,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.02098,"PCHG2":0.71979,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-28 15:09:21","ADY":316,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-270","SUBJID":"id-270","SITEID":"CHN-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":15.11156,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-13","TRTSDTM":"2019-08-17 15:09:21","TRTEDTM":"2022-08-17 09:09:21","TRT01SDTM":"2019-08-17 15:09:21","TRT01EDTM":"2021-08-17 03:09:21","TRT02SDTM":"2021-08-17 03:09:21","TRT02EDTM":"2022-08-17 09:09:21","AP01SDTM":"2019-08-17 15:09:21","AP01EDTM":"2021-08-17 03:09:21","AP02SDTM":"2021-08-17 03:09:21","AP02EDTM":"2022-08-17 09:09:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-17","EOSDY":1096,"LSTALVDT":"2022-09-02","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2472,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.69442,"AVALU":"g/L","BASE2":2.91435,"BASE":2.93532,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21993,"PCHG2":-7.54631,"CHG":-0.2409,"PCHG":-8.20703,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-10 15:09:21","ADY":390,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-270","SUBJID":"id-270","SITEID":"CHN-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":15.11156,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-13","TRTSDTM":"2019-08-17 15:09:21","TRTEDTM":"2022-08-17 09:09:21","TRT01SDTM":"2019-08-17 15:09:21","TRT01EDTM":"2021-08-17 03:09:21","TRT02SDTM":"2021-08-17 03:09:21","TRT02EDTM":"2022-08-17 09:09:21","AP01SDTM":"2019-08-17 15:09:21","AP01EDTM":"2021-08-17 03:09:21","AP02SDTM":"2021-08-17 03:09:21","AP02EDTM":"2022-08-17 09:09:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-17","EOSDY":1096,"LSTALVDT":"2022-09-02","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5518,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99574,"AVALU":"g/L","BASE2":2.91435,"BASE":2.93532,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0814,"PCHG2":2.79298,"CHG":0.06042,"PCHG":2.05837,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-19 15:09:21","ADY":490,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-270","SUBJID":"id-270","SITEID":"CHN-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":15.11156,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-13","TRTSDTM":"2019-08-17 15:09:21","TRTEDTM":"2022-08-17 09:09:21","TRT01SDTM":"2019-08-17 15:09:21","TRT01EDTM":"2021-08-17 03:09:21","TRT02SDTM":"2021-08-17 03:09:21","TRT02EDTM":"2022-08-17 09:09:21","AP01SDTM":"2019-08-17 15:09:21","AP01EDTM":"2021-08-17 03:09:21","AP02SDTM":"2021-08-17 03:09:21","AP02EDTM":"2022-08-17 09:09:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-17","EOSDY":1096,"LSTALVDT":"2022-09-02","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1704,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81888,"AVALU":"g/L","BASE2":2.91435,"BASE":2.93532,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09547,"PCHG2":-3.27581,"CHG":-0.11645,"PCHG":-3.96705,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-09 15:09:21","ADY":815,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-270","SUBJID":"id-270","SITEID":"CHN-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":15.11156,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-13","TRTSDTM":"2019-08-17 15:09:21","TRTEDTM":"2022-08-17 09:09:21","TRT01SDTM":"2019-08-17 15:09:21","TRT01EDTM":"2021-08-17 03:09:21","TRT02SDTM":"2021-08-17 03:09:21","TRT02EDTM":"2022-08-17 09:09:21","AP01SDTM":"2019-08-17 15:09:21","AP01EDTM":"2021-08-17 03:09:21","AP02SDTM":"2021-08-17 03:09:21","AP02EDTM":"2022-08-17 09:09:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-17","EOSDY":1096,"LSTALVDT":"2022-09-02","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":176,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.72687,"AVALU":"g/L","BASE2":2.91435,"BASE":2.93532,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18748,"PCHG2":-6.43289,"CHG":-0.20845,"PCHG":-7.10157,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-10 15:09:21","ADY":936,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-270","SUBJID":"id-270","SITEID":"CHN-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":15.11156,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-13","TRTSDTM":"2019-08-17 15:09:21","TRTEDTM":"2022-08-17 09:09:21","TRT01SDTM":"2019-08-17 15:09:21","TRT01EDTM":"2021-08-17 03:09:21","TRT02SDTM":"2021-08-17 03:09:21","TRT02EDTM":"2022-08-17 09:09:21","AP01SDTM":"2019-08-17 15:09:21","AP01EDTM":"2021-08-17 03:09:21","AP02SDTM":"2021-08-17 03:09:21","AP02EDTM":"2022-08-17 09:09:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-17","EOSDY":1096,"LSTALVDT":"2022-09-02","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1682,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9415,"AVALU":"g/L","BASE2":2.91435,"BASE":2.93532,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02715,"PCHG2":0.93164,"CHG":0.00617,"PCHG":0.21033,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-14 15:09:21","ADY":1093,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-304","SUBJID":"id-304","SITEID":"CHN-13","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.79003,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-21","TRTSDTM":"2020-02-23 10:47:53","TRTEDTM":"2023-02-23 04:47:53","TRT01SDTM":"2020-02-23 10:47:53","TRT01EDTM":"2022-02-22 22:47:53","TRT02SDTM":"2022-02-22 22:47:53","TRT02EDTM":"2023-02-23 04:47:53","AP01SDTM":"2020-02-23 10:47:53","AP01EDTM":"2022-02-22 22:47:53","AP02SDTM":"2022-02-22 22:47:53","AP02EDTM":"2023-02-23 04:47:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-23","EOSDY":1096,"LSTALVDT":"2023-03-24","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5129,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.86588,"AVALU":"U/L","BASE2":33.86588,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-11 10:47:53","ADY":78,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-304","SUBJID":"id-304","SITEID":"CHN-13","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.79003,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-21","TRTSDTM":"2020-02-23 10:47:53","TRTEDTM":"2023-02-23 04:47:53","TRT01SDTM":"2020-02-23 10:47:53","TRT01EDTM":"2022-02-22 22:47:53","TRT02SDTM":"2022-02-22 22:47:53","TRT02EDTM":"2023-02-23 04:47:53","AP01SDTM":"2020-02-23 10:47:53","AP01EDTM":"2022-02-22 22:47:53","AP02SDTM":"2022-02-22 22:47:53","AP02EDTM":"2023-02-23 04:47:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-23","EOSDY":1096,"LSTALVDT":"2023-03-24","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5353,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.17453,"AVALU":"U/L","BASE2":33.86588,"BASE":15.17453,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-18.69135,"PCHG2":-55.19227,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-26 10:47:53","ADY":185,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-304","SUBJID":"id-304","SITEID":"CHN-13","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.79003,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-21","TRTSDTM":"2020-02-23 10:47:53","TRTEDTM":"2023-02-23 04:47:53","TRT01SDTM":"2020-02-23 10:47:53","TRT01EDTM":"2022-02-22 22:47:53","TRT02SDTM":"2022-02-22 22:47:53","TRT02EDTM":"2023-02-23 04:47:53","AP01SDTM":"2020-02-23 10:47:53","AP01EDTM":"2022-02-22 22:47:53","AP02SDTM":"2022-02-22 22:47:53","AP02EDTM":"2023-02-23 04:47:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-23","EOSDY":1096,"LSTALVDT":"2023-03-24","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2257,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.86942,"AVALU":"U/L","BASE2":33.86588,"BASE":15.17453,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.99646,"PCHG2":-44.28192,"CHG":3.69489,"PCHG":24.34925,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-03 10:47:53","ADY":254,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-304","SUBJID":"id-304","SITEID":"CHN-13","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.79003,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-21","TRTSDTM":"2020-02-23 10:47:53","TRTEDTM":"2023-02-23 04:47:53","TRT01SDTM":"2020-02-23 10:47:53","TRT01EDTM":"2022-02-22 22:47:53","TRT02SDTM":"2022-02-22 22:47:53","TRT02EDTM":"2023-02-23 04:47:53","AP01SDTM":"2020-02-23 10:47:53","AP01EDTM":"2022-02-22 22:47:53","AP02SDTM":"2022-02-22 22:47:53","AP02EDTM":"2023-02-23 04:47:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-23","EOSDY":1096,"LSTALVDT":"2023-03-24","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4012,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.86384,"AVALU":"U/L","BASE2":33.86588,"BASE":15.17453,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-22.00204,"PCHG2":-64.96816,"CHG":-3.31069,"PCHG":-21.81741,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-01 10:47:53","ADY":433,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-304","SUBJID":"id-304","SITEID":"CHN-13","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.79003,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-21","TRTSDTM":"2020-02-23 10:47:53","TRTEDTM":"2023-02-23 04:47:53","TRT01SDTM":"2020-02-23 10:47:53","TRT01EDTM":"2022-02-22 22:47:53","TRT02SDTM":"2022-02-22 22:47:53","TRT02EDTM":"2023-02-23 04:47:53","AP01SDTM":"2020-02-23 10:47:53","AP01EDTM":"2022-02-22 22:47:53","AP02SDTM":"2022-02-22 22:47:53","AP02EDTM":"2023-02-23 04:47:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-23","EOSDY":1096,"LSTALVDT":"2023-03-24","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5393,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.21806,"AVALU":"U/L","BASE2":33.86588,"BASE":15.17453,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-32.64782,"PCHG2":-96.40328,"CHG":-13.95647,"PCHG":-91.973,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2022-01-19 10:47:53","ADY":696,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-304","SUBJID":"id-304","SITEID":"CHN-13","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.79003,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-21","TRTSDTM":"2020-02-23 10:47:53","TRTEDTM":"2023-02-23 04:47:53","TRT01SDTM":"2020-02-23 10:47:53","TRT01EDTM":"2022-02-22 22:47:53","TRT02SDTM":"2022-02-22 22:47:53","TRT02EDTM":"2023-02-23 04:47:53","AP01SDTM":"2020-02-23 10:47:53","AP01EDTM":"2022-02-22 22:47:53","AP02SDTM":"2022-02-22 22:47:53","AP02EDTM":"2023-02-23 04:47:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-23","EOSDY":1096,"LSTALVDT":"2023-03-24","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2355,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.70269,"AVALU":"U/L","BASE2":33.86588,"BASE":15.17453,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-21.1632,"PCHG2":-62.4912,"CHG":-2.47185,"PCHG":-16.28944,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-25 10:47:53","ADY":761,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-304","SUBJID":"id-304","SITEID":"CHN-13","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.79003,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-21","TRTSDTM":"2020-02-23 10:47:53","TRTEDTM":"2023-02-23 04:47:53","TRT01SDTM":"2020-02-23 10:47:53","TRT01EDTM":"2022-02-22 22:47:53","TRT02SDTM":"2022-02-22 22:47:53","TRT02EDTM":"2023-02-23 04:47:53","AP01SDTM":"2020-02-23 10:47:53","AP01EDTM":"2022-02-22 22:47:53","AP02SDTM":"2022-02-22 22:47:53","AP02EDTM":"2023-02-23 04:47:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-23","EOSDY":1096,"LSTALVDT":"2023-03-24","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6322,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.23851,"AVALU":"U/L","BASE2":33.86588,"BASE":15.17453,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.62738,"PCHG2":-43.19207,"CHG":4.06397,"PCHG":26.78154,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-28 10:47:53","ADY":795,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-304","SUBJID":"id-304","SITEID":"CHN-13","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.79003,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-21","TRTSDTM":"2020-02-23 10:47:53","TRTEDTM":"2023-02-23 04:47:53","TRT01SDTM":"2020-02-23 10:47:53","TRT01EDTM":"2022-02-22 22:47:53","TRT02SDTM":"2022-02-22 22:47:53","TRT02EDTM":"2023-02-23 04:47:53","AP01SDTM":"2020-02-23 10:47:53","AP01EDTM":"2022-02-22 22:47:53","AP02SDTM":"2022-02-22 22:47:53","AP02EDTM":"2023-02-23 04:47:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-23","EOSDY":1096,"LSTALVDT":"2023-03-24","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2995,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.09141,"AVALU":"mg/L","BASE2":9.09141,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-11 10:47:53","ADY":78,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-304","SUBJID":"id-304","SITEID":"CHN-13","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.79003,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-21","TRTSDTM":"2020-02-23 10:47:53","TRTEDTM":"2023-02-23 04:47:53","TRT01SDTM":"2020-02-23 10:47:53","TRT01EDTM":"2022-02-22 22:47:53","TRT02SDTM":"2022-02-22 22:47:53","TRT02EDTM":"2023-02-23 04:47:53","AP01SDTM":"2020-02-23 10:47:53","AP01EDTM":"2022-02-22 22:47:53","AP02SDTM":"2022-02-22 22:47:53","AP02EDTM":"2023-02-23 04:47:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-23","EOSDY":1096,"LSTALVDT":"2023-03-24","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1891,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.69485,"AVALU":"mg/L","BASE2":9.09141,"BASE":8.69485,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.39656,"PCHG2":-4.36195,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-26 10:47:53","ADY":185,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-304","SUBJID":"id-304","SITEID":"CHN-13","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.79003,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-21","TRTSDTM":"2020-02-23 10:47:53","TRTEDTM":"2023-02-23 04:47:53","TRT01SDTM":"2020-02-23 10:47:53","TRT01EDTM":"2022-02-22 22:47:53","TRT02SDTM":"2022-02-22 22:47:53","TRT02EDTM":"2023-02-23 04:47:53","AP01SDTM":"2020-02-23 10:47:53","AP01EDTM":"2022-02-22 22:47:53","AP02SDTM":"2022-02-22 22:47:53","AP02EDTM":"2023-02-23 04:47:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-23","EOSDY":1096,"LSTALVDT":"2023-03-24","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7839,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.66789,"AVALU":"mg/L","BASE2":9.09141,"BASE":8.69485,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.42352,"PCHG2":-15.65789,"CHG":-1.02696,"PCHG":-11.81114,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-11-03 10:47:53","ADY":254,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-304","SUBJID":"id-304","SITEID":"CHN-13","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.79003,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-21","TRTSDTM":"2020-02-23 10:47:53","TRTEDTM":"2023-02-23 04:47:53","TRT01SDTM":"2020-02-23 10:47:53","TRT01EDTM":"2022-02-22 22:47:53","TRT02SDTM":"2022-02-22 22:47:53","TRT02EDTM":"2023-02-23 04:47:53","AP01SDTM":"2020-02-23 10:47:53","AP01EDTM":"2022-02-22 22:47:53","AP02SDTM":"2022-02-22 22:47:53","AP02EDTM":"2023-02-23 04:47:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-23","EOSDY":1096,"LSTALVDT":"2023-03-24","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5869,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.13438,"AVALU":"mg/L","BASE2":9.09141,"BASE":8.69485,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04297,"PCHG2":0.47261,"CHG":0.43953,"PCHG":5.05506,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-01 10:47:53","ADY":433,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-304","SUBJID":"id-304","SITEID":"CHN-13","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.79003,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-21","TRTSDTM":"2020-02-23 10:47:53","TRTEDTM":"2023-02-23 04:47:53","TRT01SDTM":"2020-02-23 10:47:53","TRT01EDTM":"2022-02-22 22:47:53","TRT02SDTM":"2022-02-22 22:47:53","TRT02EDTM":"2023-02-23 04:47:53","AP01SDTM":"2020-02-23 10:47:53","AP01EDTM":"2022-02-22 22:47:53","AP02SDTM":"2022-02-22 22:47:53","AP02EDTM":"2023-02-23 04:47:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-23","EOSDY":1096,"LSTALVDT":"2023-03-24","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6564,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.65319,"AVALU":"mg/L","BASE2":9.09141,"BASE":8.69485,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.43822,"PCHG2":-4.8201,"CHG":-0.04165,"PCHG":-0.47905,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-19 10:47:53","ADY":696,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-304","SUBJID":"id-304","SITEID":"CHN-13","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.79003,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-21","TRTSDTM":"2020-02-23 10:47:53","TRTEDTM":"2023-02-23 04:47:53","TRT01SDTM":"2020-02-23 10:47:53","TRT01EDTM":"2022-02-22 22:47:53","TRT02SDTM":"2022-02-22 22:47:53","TRT02EDTM":"2023-02-23 04:47:53","AP01SDTM":"2020-02-23 10:47:53","AP01EDTM":"2022-02-22 22:47:53","AP02SDTM":"2022-02-22 22:47:53","AP02EDTM":"2023-02-23 04:47:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-23","EOSDY":1096,"LSTALVDT":"2023-03-24","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2917,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.53541,"AVALU":"mg/L","BASE2":9.09141,"BASE":8.69485,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.556,"PCHG2":-6.11565,"CHG":-0.15944,"PCHG":-1.83369,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-25 10:47:53","ADY":761,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-304","SUBJID":"id-304","SITEID":"CHN-13","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.79003,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-21","TRTSDTM":"2020-02-23 10:47:53","TRTEDTM":"2023-02-23 04:47:53","TRT01SDTM":"2020-02-23 10:47:53","TRT01EDTM":"2022-02-22 22:47:53","TRT02SDTM":"2022-02-22 22:47:53","TRT02EDTM":"2023-02-23 04:47:53","AP01SDTM":"2020-02-23 10:47:53","AP01EDTM":"2022-02-22 22:47:53","AP02SDTM":"2022-02-22 22:47:53","AP02EDTM":"2023-02-23 04:47:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-23","EOSDY":1096,"LSTALVDT":"2023-03-24","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":862,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.6106,"AVALU":"mg/L","BASE2":9.09141,"BASE":8.69485,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.48081,"PCHG2":-5.28862,"CHG":-0.08425,"PCHG":-0.96893,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-28 10:47:53","ADY":795,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-304","SUBJID":"id-304","SITEID":"CHN-13","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.79003,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-21","TRTSDTM":"2020-02-23 10:47:53","TRTEDTM":"2023-02-23 04:47:53","TRT01SDTM":"2020-02-23 10:47:53","TRT01EDTM":"2022-02-22 22:47:53","TRT02SDTM":"2022-02-22 22:47:53","TRT02EDTM":"2023-02-23 04:47:53","AP01SDTM":"2020-02-23 10:47:53","AP01EDTM":"2022-02-22 22:47:53","AP02SDTM":"2022-02-22 22:47:53","AP02EDTM":"2023-02-23 04:47:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-23","EOSDY":1096,"LSTALVDT":"2023-03-24","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1851,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82616,"AVALU":"g/L","BASE2":2.82616,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-11 10:47:53","ADY":78,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-304","SUBJID":"id-304","SITEID":"CHN-13","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.79003,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-21","TRTSDTM":"2020-02-23 10:47:53","TRTEDTM":"2023-02-23 04:47:53","TRT01SDTM":"2020-02-23 10:47:53","TRT01EDTM":"2022-02-22 22:47:53","TRT02SDTM":"2022-02-22 22:47:53","TRT02EDTM":"2023-02-23 04:47:53","AP01SDTM":"2020-02-23 10:47:53","AP01EDTM":"2022-02-22 22:47:53","AP02SDTM":"2022-02-22 22:47:53","AP02EDTM":"2023-02-23 04:47:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-23","EOSDY":1096,"LSTALVDT":"2023-03-24","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6488,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88344,"AVALU":"g/L","BASE2":2.82616,"BASE":2.88344,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.05729,"PCHG2":2.02701,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-26 10:47:53","ADY":185,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-304","SUBJID":"id-304","SITEID":"CHN-13","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.79003,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-21","TRTSDTM":"2020-02-23 10:47:53","TRTEDTM":"2023-02-23 04:47:53","TRT01SDTM":"2020-02-23 10:47:53","TRT01EDTM":"2022-02-22 22:47:53","TRT02SDTM":"2022-02-22 22:47:53","TRT02EDTM":"2023-02-23 04:47:53","AP01SDTM":"2020-02-23 10:47:53","AP01EDTM":"2022-02-22 22:47:53","AP02SDTM":"2022-02-22 22:47:53","AP02EDTM":"2023-02-23 04:47:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-23","EOSDY":1096,"LSTALVDT":"2023-03-24","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4192,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9207,"AVALU":"g/L","BASE2":2.82616,"BASE":2.88344,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09454,"PCHG2":3.3452,"CHG":0.03725,"PCHG":1.29201,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-03 10:47:53","ADY":254,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-304","SUBJID":"id-304","SITEID":"CHN-13","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.79003,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-21","TRTSDTM":"2020-02-23 10:47:53","TRTEDTM":"2023-02-23 04:47:53","TRT01SDTM":"2020-02-23 10:47:53","TRT01EDTM":"2022-02-22 22:47:53","TRT02SDTM":"2022-02-22 22:47:53","TRT02EDTM":"2023-02-23 04:47:53","AP01SDTM":"2020-02-23 10:47:53","AP01EDTM":"2022-02-22 22:47:53","AP02SDTM":"2022-02-22 22:47:53","AP02EDTM":"2023-02-23 04:47:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-23","EOSDY":1096,"LSTALVDT":"2023-03-24","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6131,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93534,"AVALU":"g/L","BASE2":2.82616,"BASE":2.88344,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10918,"PCHG2":3.8633,"CHG":0.0519,"PCHG":1.79981,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-01 10:47:53","ADY":433,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-304","SUBJID":"id-304","SITEID":"CHN-13","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.79003,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-21","TRTSDTM":"2020-02-23 10:47:53","TRTEDTM":"2023-02-23 04:47:53","TRT01SDTM":"2020-02-23 10:47:53","TRT01EDTM":"2022-02-22 22:47:53","TRT02SDTM":"2022-02-22 22:47:53","TRT02EDTM":"2023-02-23 04:47:53","AP01SDTM":"2020-02-23 10:47:53","AP01EDTM":"2022-02-22 22:47:53","AP02SDTM":"2022-02-22 22:47:53","AP02EDTM":"2023-02-23 04:47:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-23","EOSDY":1096,"LSTALVDT":"2023-03-24","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7003,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82553,"AVALU":"g/L","BASE2":2.82616,"BASE":2.88344,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00063,"PCHG2":-0.02213,"CHG":-0.05791,"PCHG":-2.00843,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-19 10:47:53","ADY":696,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-304","SUBJID":"id-304","SITEID":"CHN-13","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.79003,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-21","TRTSDTM":"2020-02-23 10:47:53","TRTEDTM":"2023-02-23 04:47:53","TRT01SDTM":"2020-02-23 10:47:53","TRT01EDTM":"2022-02-22 22:47:53","TRT02SDTM":"2022-02-22 22:47:53","TRT02EDTM":"2023-02-23 04:47:53","AP01SDTM":"2020-02-23 10:47:53","AP01EDTM":"2022-02-22 22:47:53","AP02SDTM":"2022-02-22 22:47:53","AP02EDTM":"2023-02-23 04:47:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-23","EOSDY":1096,"LSTALVDT":"2023-03-24","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3986,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8516,"AVALU":"g/L","BASE2":2.82616,"BASE":2.88344,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02544,"PCHG2":0.90026,"CHG":-0.03184,"PCHG":-1.10437,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-25 10:47:53","ADY":761,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-13-id-304","SUBJID":"id-304","SITEID":"CHN-13","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-13","INVNAM":"Dr. CHN-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.79003,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-21","TRTSDTM":"2020-02-23 10:47:53","TRTEDTM":"2023-02-23 04:47:53","TRT01SDTM":"2020-02-23 10:47:53","TRT01EDTM":"2022-02-22 22:47:53","TRT02SDTM":"2022-02-22 22:47:53","TRT02EDTM":"2023-02-23 04:47:53","AP01SDTM":"2020-02-23 10:47:53","AP01EDTM":"2022-02-22 22:47:53","AP02SDTM":"2022-02-22 22:47:53","AP02EDTM":"2023-02-23 04:47:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-02-23","EOSDY":1096,"LSTALVDT":"2023-03-24","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2097,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01633,"AVALU":"g/L","BASE2":2.82616,"BASE":2.88344,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.19017,"PCHG2":6.7289,"CHG":0.13288,"PCHG":4.60848,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-04-28 10:47:53","ADY":795,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-1","SUBJID":"id-1","SITEID":"CHN-14","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.72251,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-06","TRTSDTM":"2019-05-07 11:59:24","TRTEDTM":"2022-05-07 05:59:24","TRT01SDTM":"2019-05-07 11:59:24","TRT01EDTM":"2021-05-06 23:59:24","TRT02SDTM":"2021-05-06 23:59:24","TRT02EDTM":"2022-05-07 05:59:24","AP01SDTM":"2019-05-07 11:59:24","AP01EDTM":"2021-05-06 23:59:24","AP02SDTM":"2021-05-06 23:59:24","AP02EDTM":"2022-05-07 05:59:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-07","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8189,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.00025,"AVALU":"U/L","BASE2":29.00025,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-20 11:59:24","ADY":74,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-1","SUBJID":"id-1","SITEID":"CHN-14","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.72251,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-06","TRTSDTM":"2019-05-07 11:59:24","TRTEDTM":"2022-05-07 05:59:24","TRT01SDTM":"2019-05-07 11:59:24","TRT01EDTM":"2021-05-06 23:59:24","TRT02SDTM":"2021-05-06 23:59:24","TRT02EDTM":"2022-05-07 05:59:24","AP01SDTM":"2019-05-07 11:59:24","AP01EDTM":"2021-05-06 23:59:24","AP02SDTM":"2021-05-06 23:59:24","AP02EDTM":"2022-05-07 05:59:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-07","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4205,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.08675,"AVALU":"U/L","BASE2":29.00025,"BASE":15.08675,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-13.9135,"PCHG2":-47.97717,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-30 11:59:24","ADY":328,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-1","SUBJID":"id-1","SITEID":"CHN-14","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.72251,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-06","TRTSDTM":"2019-05-07 11:59:24","TRTEDTM":"2022-05-07 05:59:24","TRT01SDTM":"2019-05-07 11:59:24","TRT01EDTM":"2021-05-06 23:59:24","TRT02SDTM":"2021-05-06 23:59:24","TRT02EDTM":"2022-05-07 05:59:24","AP01SDTM":"2019-05-07 11:59:24","AP01EDTM":"2021-05-06 23:59:24","AP02SDTM":"2021-05-06 23:59:24","AP02EDTM":"2022-05-07 05:59:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-07","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1725,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.2305,"AVALU":"U/L","BASE2":29.00025,"BASE":15.08675,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.23024,"PCHG2":0.79393,"CHG":14.14374,"PCHG":93.74942,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-04 11:59:24","ADY":455,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-1","SUBJID":"id-1","SITEID":"CHN-14","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.72251,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-06","TRTSDTM":"2019-05-07 11:59:24","TRTEDTM":"2022-05-07 05:59:24","TRT01SDTM":"2019-05-07 11:59:24","TRT01EDTM":"2021-05-06 23:59:24","TRT02SDTM":"2021-05-06 23:59:24","TRT02EDTM":"2022-05-07 05:59:24","AP01SDTM":"2019-05-07 11:59:24","AP01EDTM":"2021-05-06 23:59:24","AP02SDTM":"2021-05-06 23:59:24","AP02EDTM":"2022-05-07 05:59:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-07","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2904,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.10589,"AVALU":"U/L","BASE2":29.00025,"BASE":15.08675,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.89437,"PCHG2":-61.70418,"CHG":-3.98087,"PCHG":-26.38651,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-06 11:59:24","ADY":518,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-1","SUBJID":"id-1","SITEID":"CHN-14","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.72251,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-06","TRTSDTM":"2019-05-07 11:59:24","TRTEDTM":"2022-05-07 05:59:24","TRT01SDTM":"2019-05-07 11:59:24","TRT01EDTM":"2021-05-06 23:59:24","TRT02SDTM":"2021-05-06 23:59:24","TRT02EDTM":"2022-05-07 05:59:24","AP01SDTM":"2019-05-07 11:59:24","AP01EDTM":"2021-05-06 23:59:24","AP02SDTM":"2021-05-06 23:59:24","AP02EDTM":"2022-05-07 05:59:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-07","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5871,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.02335,"AVALU":"U/L","BASE2":29.00025,"BASE":15.08675,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.9769,"PCHG2":-51.64403,"CHG":-1.0634,"PCHG":-7.04856,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-02 11:59:24","ADY":575,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-1","SUBJID":"id-1","SITEID":"CHN-14","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.72251,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-06","TRTSDTM":"2019-05-07 11:59:24","TRTEDTM":"2022-05-07 05:59:24","TRT01SDTM":"2019-05-07 11:59:24","TRT01EDTM":"2021-05-06 23:59:24","TRT02SDTM":"2021-05-06 23:59:24","TRT02EDTM":"2022-05-07 05:59:24","AP01SDTM":"2019-05-07 11:59:24","AP01EDTM":"2021-05-06 23:59:24","AP02SDTM":"2021-05-06 23:59:24","AP02EDTM":"2022-05-07 05:59:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-07","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6686,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.00316,"AVALU":"U/L","BASE2":29.00025,"BASE":15.08675,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.0029,"PCHG2":17.25124,"CHG":18.9164,"PCHG":125.38421,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-09 11:59:24","ADY":886,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-1","SUBJID":"id-1","SITEID":"CHN-14","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.72251,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-06","TRTSDTM":"2019-05-07 11:59:24","TRTEDTM":"2022-05-07 05:59:24","TRT01SDTM":"2019-05-07 11:59:24","TRT01EDTM":"2021-05-06 23:59:24","TRT02SDTM":"2021-05-06 23:59:24","TRT02EDTM":"2022-05-07 05:59:24","AP01SDTM":"2019-05-07 11:59:24","AP01EDTM":"2021-05-06 23:59:24","AP02SDTM":"2021-05-06 23:59:24","AP02EDTM":"2022-05-07 05:59:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-07","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":640,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.53907,"AVALU":"U/L","BASE2":29.00025,"BASE":15.08675,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.46118,"PCHG2":-15.38326,"CHG":9.45232,"PCHG":62.65309,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-28 11:59:24","ADY":997,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-1","SUBJID":"id-1","SITEID":"CHN-14","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.72251,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-06","TRTSDTM":"2019-05-07 11:59:24","TRTEDTM":"2022-05-07 05:59:24","TRT01SDTM":"2019-05-07 11:59:24","TRT01EDTM":"2021-05-06 23:59:24","TRT02SDTM":"2021-05-06 23:59:24","TRT02EDTM":"2022-05-07 05:59:24","AP01SDTM":"2019-05-07 11:59:24","AP01EDTM":"2021-05-06 23:59:24","AP02SDTM":"2021-05-06 23:59:24","AP02EDTM":"2022-05-07 05:59:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-07","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":477,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.68827,"AVALU":"mg/L","BASE2":7.68827,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-4","BTOXGR":"0","ADTM":"2019-07-20 11:59:24","ADY":74,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-1","SUBJID":"id-1","SITEID":"CHN-14","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.72251,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-06","TRTSDTM":"2019-05-07 11:59:24","TRTEDTM":"2022-05-07 05:59:24","TRT01SDTM":"2019-05-07 11:59:24","TRT01EDTM":"2021-05-06 23:59:24","TRT02SDTM":"2021-05-06 23:59:24","TRT02EDTM":"2022-05-07 05:59:24","AP01SDTM":"2019-05-07 11:59:24","AP01EDTM":"2021-05-06 23:59:24","AP02SDTM":"2021-05-06 23:59:24","AP02EDTM":"2022-05-07 05:59:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-07","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":138,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.92735,"AVALU":"mg/L","BASE2":7.68827,"BASE":9.92735,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.23908,"PCHG2":29.12329,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-30 11:59:24","ADY":328,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-1","SUBJID":"id-1","SITEID":"CHN-14","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.72251,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-06","TRTSDTM":"2019-05-07 11:59:24","TRTEDTM":"2022-05-07 05:59:24","TRT01SDTM":"2019-05-07 11:59:24","TRT01EDTM":"2021-05-06 23:59:24","TRT02SDTM":"2021-05-06 23:59:24","TRT02EDTM":"2022-05-07 05:59:24","AP01SDTM":"2019-05-07 11:59:24","AP01EDTM":"2021-05-06 23:59:24","AP02SDTM":"2021-05-06 23:59:24","AP02EDTM":"2022-05-07 05:59:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-07","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3748,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.83749,"AVALU":"mg/L","BASE2":7.68827,"BASE":9.92735,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.14922,"PCHG2":27.9545,"CHG":-0.08986,"PCHG":-0.90518,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-04 11:59:24","ADY":455,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-1","SUBJID":"id-1","SITEID":"CHN-14","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.72251,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-06","TRTSDTM":"2019-05-07 11:59:24","TRTEDTM":"2022-05-07 05:59:24","TRT01SDTM":"2019-05-07 11:59:24","TRT01EDTM":"2021-05-06 23:59:24","TRT02SDTM":"2021-05-06 23:59:24","TRT02EDTM":"2022-05-07 05:59:24","AP01SDTM":"2019-05-07 11:59:24","AP01EDTM":"2021-05-06 23:59:24","AP02SDTM":"2021-05-06 23:59:24","AP02EDTM":"2022-05-07 05:59:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-07","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7989,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.03103,"AVALU":"mg/L","BASE2":7.68827,"BASE":9.92735,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.34275,"PCHG2":4.45813,"CHG":-1.89632,"PCHG":-19.10202,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-06 11:59:24","ADY":518,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-1","SUBJID":"id-1","SITEID":"CHN-14","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.72251,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-06","TRTSDTM":"2019-05-07 11:59:24","TRTEDTM":"2022-05-07 05:59:24","TRT01SDTM":"2019-05-07 11:59:24","TRT01EDTM":"2021-05-06 23:59:24","TRT02SDTM":"2021-05-06 23:59:24","TRT02EDTM":"2022-05-07 05:59:24","AP01SDTM":"2019-05-07 11:59:24","AP01EDTM":"2021-05-06 23:59:24","AP02SDTM":"2021-05-06 23:59:24","AP02EDTM":"2022-05-07 05:59:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-07","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6058,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.55927,"AVALU":"mg/L","BASE2":7.68827,"BASE":9.92735,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.871,"PCHG2":11.32897,"CHG":-1.36808,"PCHG":-13.78087,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-02 11:59:24","ADY":575,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-1","SUBJID":"id-1","SITEID":"CHN-14","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.72251,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-06","TRTSDTM":"2019-05-07 11:59:24","TRTEDTM":"2022-05-07 05:59:24","TRT01SDTM":"2019-05-07 11:59:24","TRT01EDTM":"2021-05-06 23:59:24","TRT02SDTM":"2021-05-06 23:59:24","TRT02EDTM":"2022-05-07 05:59:24","AP01SDTM":"2019-05-07 11:59:24","AP01EDTM":"2021-05-06 23:59:24","AP02SDTM":"2021-05-06 23:59:24","AP02EDTM":"2022-05-07 05:59:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-07","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2370,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.20285,"AVALU":"mg/L","BASE2":7.68827,"BASE":9.92735,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.51458,"PCHG2":19.69987,"CHG":-0.7245,"PCHG":-7.298,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-09 11:59:24","ADY":886,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-1","SUBJID":"id-1","SITEID":"CHN-14","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.72251,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-06","TRTSDTM":"2019-05-07 11:59:24","TRTEDTM":"2022-05-07 05:59:24","TRT01SDTM":"2019-05-07 11:59:24","TRT01EDTM":"2021-05-06 23:59:24","TRT02SDTM":"2021-05-06 23:59:24","TRT02EDTM":"2022-05-07 05:59:24","AP01SDTM":"2019-05-07 11:59:24","AP01EDTM":"2021-05-06 23:59:24","AP02SDTM":"2021-05-06 23:59:24","AP02EDTM":"2022-05-07 05:59:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-07","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7890,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.5416,"AVALU":"mg/L","BASE2":7.68827,"BASE":9.92735,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14667,"PCHG2":-1.90777,"CHG":-2.38575,"PCHG":-24.03212,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-01-28 11:59:24","ADY":997,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-1","SUBJID":"id-1","SITEID":"CHN-14","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.72251,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-06","TRTSDTM":"2019-05-07 11:59:24","TRTEDTM":"2022-05-07 05:59:24","TRT01SDTM":"2019-05-07 11:59:24","TRT01EDTM":"2021-05-06 23:59:24","TRT02SDTM":"2021-05-06 23:59:24","TRT02EDTM":"2022-05-07 05:59:24","AP01SDTM":"2019-05-07 11:59:24","AP01EDTM":"2021-05-06 23:59:24","AP02SDTM":"2021-05-06 23:59:24","AP02EDTM":"2022-05-07 05:59:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-07","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7250,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.09336,"AVALU":"g/L","BASE2":3.09336,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2019-07-20 11:59:24","ADY":74,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-1","SUBJID":"id-1","SITEID":"CHN-14","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.72251,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-06","TRTSDTM":"2019-05-07 11:59:24","TRTEDTM":"2022-05-07 05:59:24","TRT01SDTM":"2019-05-07 11:59:24","TRT01EDTM":"2021-05-06 23:59:24","TRT02SDTM":"2021-05-06 23:59:24","TRT02EDTM":"2022-05-07 05:59:24","AP01SDTM":"2019-05-07 11:59:24","AP01EDTM":"2021-05-06 23:59:24","AP02SDTM":"2021-05-06 23:59:24","AP02EDTM":"2022-05-07 05:59:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-07","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7047,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00588,"AVALU":"g/L","BASE2":3.09336,"BASE":3.00588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.08748,"PCHG2":-2.82807,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-03-30 11:59:24","ADY":328,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-1","SUBJID":"id-1","SITEID":"CHN-14","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.72251,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-06","TRTSDTM":"2019-05-07 11:59:24","TRTEDTM":"2022-05-07 05:59:24","TRT01SDTM":"2019-05-07 11:59:24","TRT01EDTM":"2021-05-06 23:59:24","TRT02SDTM":"2021-05-06 23:59:24","TRT02EDTM":"2022-05-07 05:59:24","AP01SDTM":"2019-05-07 11:59:24","AP01EDTM":"2021-05-06 23:59:24","AP02SDTM":"2021-05-06 23:59:24","AP02EDTM":"2022-05-07 05:59:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-07","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5426,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88624,"AVALU":"g/L","BASE2":3.09336,"BASE":3.00588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20712,"PCHG2":-6.69551,"CHG":-0.11963,"PCHG":-3.98,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-08-04 11:59:24","ADY":455,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-1","SUBJID":"id-1","SITEID":"CHN-14","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.72251,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-06","TRTSDTM":"2019-05-07 11:59:24","TRTEDTM":"2022-05-07 05:59:24","TRT01SDTM":"2019-05-07 11:59:24","TRT01EDTM":"2021-05-06 23:59:24","TRT02SDTM":"2021-05-06 23:59:24","TRT02EDTM":"2022-05-07 05:59:24","AP01SDTM":"2019-05-07 11:59:24","AP01EDTM":"2021-05-06 23:59:24","AP02SDTM":"2021-05-06 23:59:24","AP02EDTM":"2022-05-07 05:59:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-07","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3071,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04437,"AVALU":"g/L","BASE2":3.09336,"BASE":3.00588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04899,"PCHG2":-1.58369,"CHG":0.03849,"PCHG":1.2806,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"1","ADTM":"2020-10-06 11:59:24","ADY":518,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-1","SUBJID":"id-1","SITEID":"CHN-14","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.72251,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-06","TRTSDTM":"2019-05-07 11:59:24","TRTEDTM":"2022-05-07 05:59:24","TRT01SDTM":"2019-05-07 11:59:24","TRT01EDTM":"2021-05-06 23:59:24","TRT02SDTM":"2021-05-06 23:59:24","TRT02EDTM":"2022-05-07 05:59:24","AP01SDTM":"2019-05-07 11:59:24","AP01EDTM":"2021-05-06 23:59:24","AP02SDTM":"2021-05-06 23:59:24","AP02EDTM":"2022-05-07 05:59:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-07","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5389,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9116,"AVALU":"g/L","BASE2":3.09336,"BASE":3.00588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18175,"PCHG2":-5.87564,"CHG":-0.09427,"PCHG":-3.13627,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-12-02 11:59:24","ADY":575,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-1","SUBJID":"id-1","SITEID":"CHN-14","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.72251,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-06","TRTSDTM":"2019-05-07 11:59:24","TRTEDTM":"2022-05-07 05:59:24","TRT01SDTM":"2019-05-07 11:59:24","TRT01EDTM":"2021-05-06 23:59:24","TRT02SDTM":"2021-05-06 23:59:24","TRT02EDTM":"2022-05-07 05:59:24","AP01SDTM":"2019-05-07 11:59:24","AP01EDTM":"2021-05-06 23:59:24","AP02SDTM":"2021-05-06 23:59:24","AP02EDTM":"2022-05-07 05:59:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-07","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6269,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96729,"AVALU":"g/L","BASE2":3.09336,"BASE":3.00588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12607,"PCHG2":-4.07537,"CHG":-0.03858,"PCHG":-1.2836,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-10-09 11:59:24","ADY":886,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-1","SUBJID":"id-1","SITEID":"CHN-14","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.72251,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-06","TRTSDTM":"2019-05-07 11:59:24","TRTEDTM":"2022-05-07 05:59:24","TRT01SDTM":"2019-05-07 11:59:24","TRT01EDTM":"2021-05-06 23:59:24","TRT02SDTM":"2021-05-06 23:59:24","TRT02EDTM":"2022-05-07 05:59:24","AP01SDTM":"2019-05-07 11:59:24","AP01EDTM":"2021-05-06 23:59:24","AP02SDTM":"2021-05-06 23:59:24","AP02EDTM":"2022-05-07 05:59:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-07","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":209,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84749,"AVALU":"g/L","BASE2":3.09336,"BASE":3.00588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.24586,"PCHG2":-7.94814,"CHG":-0.15838,"PCHG":-5.26908,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2022-01-28 11:59:24","ADY":997,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-103","SUBJID":"id-103","SITEID":"CHN-14","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.7478,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-30","TRTSDTM":"2019-11-03 00:05:39","TRT01SDTM":"2019-11-03 00:05:39","AP01SDTM":"2019-11-03 00:05:39","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7242,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.31496,"AVALU":"U/L","BASE2":23.31496,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-08 00:05:39","ADY":310,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-103","SUBJID":"id-103","SITEID":"CHN-14","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.7478,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-30","TRTSDTM":"2019-11-03 00:05:39","TRT01SDTM":"2019-11-03 00:05:39","AP01SDTM":"2019-11-03 00:05:39","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":362,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.62416,"AVALU":"U/L","BASE2":23.31496,"BASE":15.62416,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-7.6908,"PCHG2":-32.98656,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-12 00:05:39","ADY":375,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-103","SUBJID":"id-103","SITEID":"CHN-14","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.7478,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-30","TRTSDTM":"2019-11-03 00:05:39","TRT01SDTM":"2019-11-03 00:05:39","AP01SDTM":"2019-11-03 00:05:39","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4908,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.82699,"AVALU":"U/L","BASE2":23.31496,"BASE":15.62416,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.48798,"PCHG2":-19.24934,"CHG":3.20283,"PCHG":20.4992,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-02 00:05:39","ADY":395,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-103","SUBJID":"id-103","SITEID":"CHN-14","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.7478,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-30","TRTSDTM":"2019-11-03 00:05:39","TRT01SDTM":"2019-11-03 00:05:39","AP01SDTM":"2019-11-03 00:05:39","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.99748,"AVALU":"U/L","BASE2":23.31496,"BASE":15.62416,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.31748,"PCHG2":-44.25262,"CHG":-2.62668,"PCHG":-16.81165,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-09 00:05:39","ADY":402,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-103","SUBJID":"id-103","SITEID":"CHN-14","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.7478,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-30","TRTSDTM":"2019-11-03 00:05:39","TRT01SDTM":"2019-11-03 00:05:39","AP01SDTM":"2019-11-03 00:05:39","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4785,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":38.5939,"AVALU":"U/L","BASE2":23.31496,"BASE":15.62416,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.27894,"PCHG2":65.53276,"CHG":22.96974,"PCHG":147.01425,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-17 00:05:39","ADY":472,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-103","SUBJID":"id-103","SITEID":"CHN-14","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.7478,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-30","TRTSDTM":"2019-11-03 00:05:39","TRT01SDTM":"2019-11-03 00:05:39","AP01SDTM":"2019-11-03 00:05:39","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2258,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.91247,"AVALU":"U/L","BASE2":23.31496,"BASE":15.62416,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.40249,"PCHG2":-18.88268,"CHG":3.28831,"PCHG":21.04634,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-08 00:05:39","ADY":613,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-103","SUBJID":"id-103","SITEID":"CHN-14","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.7478,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-30","TRTSDTM":"2019-11-03 00:05:39","TRT01SDTM":"2019-11-03 00:05:39","AP01SDTM":"2019-11-03 00:05:39","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":276,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.10777,"AVALU":"U/L","BASE2":23.31496,"BASE":15.62416,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-22.20719,"PCHG2":-95.24867,"CHG":-14.51639,"PCHG":-92.90989,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-10-01 00:05:39","ADY":698,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-103","SUBJID":"id-103","SITEID":"CHN-14","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.7478,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-30","TRTSDTM":"2019-11-03 00:05:39","TRT01SDTM":"2019-11-03 00:05:39","AP01SDTM":"2019-11-03 00:05:39","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3020,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.14702,"AVALU":"mg/L","BASE2":9.14702,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-08 00:05:39","ADY":310,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-103","SUBJID":"id-103","SITEID":"CHN-14","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.7478,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-30","TRTSDTM":"2019-11-03 00:05:39","TRT01SDTM":"2019-11-03 00:05:39","AP01SDTM":"2019-11-03 00:05:39","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3119,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.91807,"AVALU":"mg/L","BASE2":9.14702,"BASE":8.91807,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.22896,"PCHG2":-2.50306,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-12 00:05:39","ADY":375,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-103","SUBJID":"id-103","SITEID":"CHN-14","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.7478,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-30","TRTSDTM":"2019-11-03 00:05:39","TRT01SDTM":"2019-11-03 00:05:39","AP01SDTM":"2019-11-03 00:05:39","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4269,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.79354,"AVALU":"mg/L","BASE2":9.14702,"BASE":8.91807,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.35348,"PCHG2":-14.79694,"CHG":-1.12452,"PCHG":-12.6095,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-12-02 00:05:39","ADY":395,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-103","SUBJID":"id-103","SITEID":"CHN-14","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.7478,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-30","TRTSDTM":"2019-11-03 00:05:39","TRT01SDTM":"2019-11-03 00:05:39","AP01SDTM":"2019-11-03 00:05:39","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7931,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.07592,"AVALU":"mg/L","BASE2":9.14702,"BASE":8.91807,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07111,"PCHG2":-0.77737,"CHG":0.15785,"PCHG":1.76999,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-09 00:05:39","ADY":402,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-103","SUBJID":"id-103","SITEID":"CHN-14","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.7478,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-30","TRTSDTM":"2019-11-03 00:05:39","TRT01SDTM":"2019-11-03 00:05:39","AP01SDTM":"2019-11-03 00:05:39","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3523,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.83956,"AVALU":"mg/L","BASE2":9.14702,"BASE":8.91807,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.30746,"PCHG2":-3.36131,"CHG":-0.0785,"PCHG":-0.88028,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-17 00:05:39","ADY":472,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-103","SUBJID":"id-103","SITEID":"CHN-14","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.7478,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-30","TRTSDTM":"2019-11-03 00:05:39","TRT01SDTM":"2019-11-03 00:05:39","AP01SDTM":"2019-11-03 00:05:39","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":95,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.48968,"AVALU":"mg/L","BASE2":9.14702,"BASE":8.91807,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.34266,"PCHG2":14.67864,"CHG":1.57161,"PCHG":17.62281,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-07-08 00:05:39","ADY":613,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-103","SUBJID":"id-103","SITEID":"CHN-14","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.7478,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-30","TRTSDTM":"2019-11-03 00:05:39","TRT01SDTM":"2019-11-03 00:05:39","AP01SDTM":"2019-11-03 00:05:39","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2847,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.07672,"AVALU":"mg/L","BASE2":9.14702,"BASE":8.91807,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.0703,"PCHG2":-22.63359,"CHG":-1.84134,"PCHG":-20.64735,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-10-01 00:05:39","ADY":698,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-103","SUBJID":"id-103","SITEID":"CHN-14","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.7478,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-30","TRTSDTM":"2019-11-03 00:05:39","TRT01SDTM":"2019-11-03 00:05:39","AP01SDTM":"2019-11-03 00:05:39","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6734,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.72781,"AVALU":"g/L","BASE2":2.72781,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-09-08 00:05:39","ADY":310,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-103","SUBJID":"id-103","SITEID":"CHN-14","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.7478,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-30","TRTSDTM":"2019-11-03 00:05:39","TRT01SDTM":"2019-11-03 00:05:39","AP01SDTM":"2019-11-03 00:05:39","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6066,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00094,"AVALU":"g/L","BASE2":2.72781,"BASE":3.00094,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.27313,"PCHG2":10.01289,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-11-12 00:05:39","ADY":375,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-103","SUBJID":"id-103","SITEID":"CHN-14","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.7478,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-30","TRTSDTM":"2019-11-03 00:05:39","TRT01SDTM":"2019-11-03 00:05:39","AP01SDTM":"2019-11-03 00:05:39","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":486,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92852,"AVALU":"g/L","BASE2":2.72781,"BASE":3.00094,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.20071,"PCHG2":7.35798,"CHG":-0.07242,"PCHG":-2.41327,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-12-02 00:05:39","ADY":395,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-103","SUBJID":"id-103","SITEID":"CHN-14","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.7478,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-30","TRTSDTM":"2019-11-03 00:05:39","TRT01SDTM":"2019-11-03 00:05:39","AP01SDTM":"2019-11-03 00:05:39","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7978,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81015,"AVALU":"g/L","BASE2":2.72781,"BASE":3.00094,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08234,"PCHG2":3.0187,"CHG":-0.19079,"PCHG":-6.35761,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-12-09 00:05:39","ADY":402,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-103","SUBJID":"id-103","SITEID":"CHN-14","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.7478,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-30","TRTSDTM":"2019-11-03 00:05:39","TRT01SDTM":"2019-11-03 00:05:39","AP01SDTM":"2019-11-03 00:05:39","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5635,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93815,"AVALU":"g/L","BASE2":2.72781,"BASE":3.00094,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.21034,"PCHG2":7.71076,"CHG":-0.0628,"PCHG":-2.09259,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-02-17 00:05:39","ADY":472,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-103","SUBJID":"id-103","SITEID":"CHN-14","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.7478,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-30","TRTSDTM":"2019-11-03 00:05:39","TRT01SDTM":"2019-11-03 00:05:39","AP01SDTM":"2019-11-03 00:05:39","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3153,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91182,"AVALU":"g/L","BASE2":2.72781,"BASE":3.00094,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18401,"PCHG2":6.74554,"CHG":-0.08913,"PCHG":-2.96997,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-07-08 00:05:39","ADY":613,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-103","SUBJID":"id-103","SITEID":"CHN-14","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.7478,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-30","TRTSDTM":"2019-11-03 00:05:39","TRT01SDTM":"2019-11-03 00:05:39","AP01SDTM":"2019-11-03 00:05:39","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3252,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02395,"AVALU":"g/L","BASE2":2.72781,"BASE":3.00094,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.29614,"PCHG2":10.85616,"CHG":0.023,"PCHG":0.76652,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"3","BTOXGR":"1","ADTM":"2021-10-01 00:05:39","ADY":698,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-143","SUBJID":"id-143","SITEID":"CHN-14","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.17717,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-07 11:36:40","TRTEDTM":"2023-08-08 05:36:40","TRT01SDTM":"2020-08-07 11:36:40","TRT01EDTM":"2022-08-07 23:36:40","TRT02SDTM":"2022-08-07 23:36:40","TRT02EDTM":"2023-08-08 05:36:40","AP01SDTM":"2020-08-07 11:36:40","AP01EDTM":"2022-08-07 23:36:40","AP02SDTM":"2022-08-07 23:36:40","AP02EDTM":"2023-08-08 05:36:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-08","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6633,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.73743,"AVALU":"U/L","BASE2":3.73743,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-06-24 11:36:40","ADY":321,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-143","SUBJID":"id-143","SITEID":"CHN-14","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.17717,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-07 11:36:40","TRTEDTM":"2023-08-08 05:36:40","TRT01SDTM":"2020-08-07 11:36:40","TRT01EDTM":"2022-08-07 23:36:40","TRT02SDTM":"2022-08-07 23:36:40","TRT02EDTM":"2023-08-08 05:36:40","AP01SDTM":"2020-08-07 11:36:40","AP01EDTM":"2022-08-07 23:36:40","AP02SDTM":"2022-08-07 23:36:40","AP02EDTM":"2023-08-08 05:36:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-08","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":874,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.95188,"AVALU":"U/L","BASE2":3.73743,"BASE":28.95188,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":25.21445,"PCHG2":674.64739,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-03 11:36:40","ADY":361,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-143","SUBJID":"id-143","SITEID":"CHN-14","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.17717,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-07 11:36:40","TRTEDTM":"2023-08-08 05:36:40","TRT01SDTM":"2020-08-07 11:36:40","TRT01EDTM":"2022-08-07 23:36:40","TRT02SDTM":"2022-08-07 23:36:40","TRT02EDTM":"2023-08-08 05:36:40","AP01SDTM":"2020-08-07 11:36:40","AP01EDTM":"2022-08-07 23:36:40","AP02SDTM":"2022-08-07 23:36:40","AP02EDTM":"2023-08-08 05:36:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-08","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5446,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.3608,"AVALU":"U/L","BASE2":3.73743,"BASE":28.95188,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":23.62338,"PCHG2":632.07605,"CHG":-1.59107,"PCHG":-5.49558,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-22 11:36:40","ADY":592,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-143","SUBJID":"id-143","SITEID":"CHN-14","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.17717,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-07 11:36:40","TRTEDTM":"2023-08-08 05:36:40","TRT01SDTM":"2020-08-07 11:36:40","TRT01EDTM":"2022-08-07 23:36:40","TRT02SDTM":"2022-08-07 23:36:40","TRT02EDTM":"2023-08-08 05:36:40","AP01SDTM":"2020-08-07 11:36:40","AP01EDTM":"2022-08-07 23:36:40","AP02SDTM":"2022-08-07 23:36:40","AP02EDTM":"2023-08-08 05:36:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-08","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2572,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.50519,"AVALU":"U/L","BASE2":3.73743,"BASE":28.95188,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.76777,"PCHG2":181.08091,"CHG":-18.44669,"PCHG":-63.71499,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-24 11:36:40","ADY":594,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-143","SUBJID":"id-143","SITEID":"CHN-14","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.17717,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-07 11:36:40","TRTEDTM":"2023-08-08 05:36:40","TRT01SDTM":"2020-08-07 11:36:40","TRT01EDTM":"2022-08-07 23:36:40","TRT02SDTM":"2022-08-07 23:36:40","TRT02EDTM":"2023-08-08 05:36:40","AP01SDTM":"2020-08-07 11:36:40","AP01EDTM":"2022-08-07 23:36:40","AP02SDTM":"2022-08-07 23:36:40","AP02EDTM":"2023-08-08 05:36:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-08","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5599,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.50852,"AVALU":"U/L","BASE2":3.73743,"BASE":28.95188,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":20.77109,"PCHG2":555.75924,"CHG":-4.44336,"PCHG":-15.34739,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-03 11:36:40","ADY":604,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-143","SUBJID":"id-143","SITEID":"CHN-14","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.17717,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-07 11:36:40","TRTEDTM":"2023-08-08 05:36:40","TRT01SDTM":"2020-08-07 11:36:40","TRT01EDTM":"2022-08-07 23:36:40","TRT02SDTM":"2022-08-07 23:36:40","TRT02EDTM":"2023-08-08 05:36:40","AP01SDTM":"2020-08-07 11:36:40","AP01EDTM":"2022-08-07 23:36:40","AP02SDTM":"2022-08-07 23:36:40","AP02EDTM":"2023-08-08 05:36:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-08","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":37,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.99129,"AVALU":"U/L","BASE2":3.73743,"BASE":28.95188,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":31.25386,"PCHG2":836.24008,"CHG":6.03941,"PCHG":20.86016,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-14 11:36:40","ADY":859,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-143","SUBJID":"id-143","SITEID":"CHN-14","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.17717,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-07 11:36:40","TRTEDTM":"2023-08-08 05:36:40","TRT01SDTM":"2020-08-07 11:36:40","TRT01EDTM":"2022-08-07 23:36:40","TRT02SDTM":"2022-08-07 23:36:40","TRT02EDTM":"2023-08-08 05:36:40","AP01SDTM":"2020-08-07 11:36:40","AP01EDTM":"2022-08-07 23:36:40","AP02SDTM":"2022-08-07 23:36:40","AP02EDTM":"2023-08-08 05:36:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-08","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8224,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.14271,"AVALU":"U/L","BASE2":3.73743,"BASE":28.95188,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.40529,"PCHG2":412.18971,"CHG":-9.80916,"PCHG":-33.88092,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-14 11:36:40","ADY":1010,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-143","SUBJID":"id-143","SITEID":"CHN-14","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.17717,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-07 11:36:40","TRTEDTM":"2023-08-08 05:36:40","TRT01SDTM":"2020-08-07 11:36:40","TRT01EDTM":"2022-08-07 23:36:40","TRT02SDTM":"2022-08-07 23:36:40","TRT02EDTM":"2023-08-08 05:36:40","AP01SDTM":"2020-08-07 11:36:40","AP01EDTM":"2022-08-07 23:36:40","AP02SDTM":"2022-08-07 23:36:40","AP02EDTM":"2023-08-08 05:36:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-08","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2660,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.95923,"AVALU":"mg/L","BASE2":8.95923,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-24 11:36:40","ADY":321,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-143","SUBJID":"id-143","SITEID":"CHN-14","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.17717,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-07 11:36:40","TRTEDTM":"2023-08-08 05:36:40","TRT01SDTM":"2020-08-07 11:36:40","TRT01EDTM":"2022-08-07 23:36:40","TRT02SDTM":"2022-08-07 23:36:40","TRT02EDTM":"2023-08-08 05:36:40","AP01SDTM":"2020-08-07 11:36:40","AP01EDTM":"2022-08-07 23:36:40","AP02SDTM":"2022-08-07 23:36:40","AP02EDTM":"2023-08-08 05:36:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-08","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7096,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.78014,"AVALU":"mg/L","BASE2":8.95923,"BASE":8.78014,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.17909,"PCHG2":-1.99897,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-03 11:36:40","ADY":361,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-143","SUBJID":"id-143","SITEID":"CHN-14","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.17717,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-07 11:36:40","TRTEDTM":"2023-08-08 05:36:40","TRT01SDTM":"2020-08-07 11:36:40","TRT01EDTM":"2022-08-07 23:36:40","TRT02SDTM":"2022-08-07 23:36:40","TRT02EDTM":"2023-08-08 05:36:40","AP01SDTM":"2020-08-07 11:36:40","AP01EDTM":"2022-08-07 23:36:40","AP02SDTM":"2022-08-07 23:36:40","AP02EDTM":"2023-08-08 05:36:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-08","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":52,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.65179,"AVALU":"mg/L","BASE2":8.95923,"BASE":8.78014,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.30744,"PCHG2":-3.43155,"CHG":-0.12835,"PCHG":-1.46179,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-22 11:36:40","ADY":592,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-143","SUBJID":"id-143","SITEID":"CHN-14","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.17717,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-07 11:36:40","TRTEDTM":"2023-08-08 05:36:40","TRT01SDTM":"2020-08-07 11:36:40","TRT01EDTM":"2022-08-07 23:36:40","TRT02SDTM":"2022-08-07 23:36:40","TRT02EDTM":"2023-08-08 05:36:40","AP01SDTM":"2020-08-07 11:36:40","AP01EDTM":"2022-08-07 23:36:40","AP02SDTM":"2022-08-07 23:36:40","AP02EDTM":"2023-08-08 05:36:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-08","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5905,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.35124,"AVALU":"mg/L","BASE2":8.95923,"BASE":8.78014,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.60799,"PCHG2":-6.78614,"CHG":-0.42889,"PCHG":-4.88481,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-24 11:36:40","ADY":594,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-143","SUBJID":"id-143","SITEID":"CHN-14","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.17717,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-07 11:36:40","TRTEDTM":"2023-08-08 05:36:40","TRT01SDTM":"2020-08-07 11:36:40","TRT01EDTM":"2022-08-07 23:36:40","TRT02SDTM":"2022-08-07 23:36:40","TRT02EDTM":"2023-08-08 05:36:40","AP01SDTM":"2020-08-07 11:36:40","AP01EDTM":"2022-08-07 23:36:40","AP02SDTM":"2022-08-07 23:36:40","AP02EDTM":"2023-08-08 05:36:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-08","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8144,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.25242,"AVALU":"mg/L","BASE2":8.95923,"BASE":8.78014,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.29319,"PCHG2":14.43422,"CHG":1.47229,"PCHG":16.76839,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-04-03 11:36:40","ADY":604,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-143","SUBJID":"id-143","SITEID":"CHN-14","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.17717,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-07 11:36:40","TRTEDTM":"2023-08-08 05:36:40","TRT01SDTM":"2020-08-07 11:36:40","TRT01EDTM":"2022-08-07 23:36:40","TRT02SDTM":"2022-08-07 23:36:40","TRT02EDTM":"2023-08-08 05:36:40","AP01SDTM":"2020-08-07 11:36:40","AP01EDTM":"2022-08-07 23:36:40","AP02SDTM":"2022-08-07 23:36:40","AP02EDTM":"2023-08-08 05:36:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-08","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5271,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.44454,"AVALU":"mg/L","BASE2":8.95923,"BASE":8.78014,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.48531,"PCHG2":5.41684,"CHG":0.6644,"PCHG":7.56708,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-14 11:36:40","ADY":859,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-143","SUBJID":"id-143","SITEID":"CHN-14","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.17717,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-07 11:36:40","TRTEDTM":"2023-08-08 05:36:40","TRT01SDTM":"2020-08-07 11:36:40","TRT01EDTM":"2022-08-07 23:36:40","TRT02SDTM":"2022-08-07 23:36:40","TRT02EDTM":"2023-08-08 05:36:40","AP01SDTM":"2020-08-07 11:36:40","AP01EDTM":"2022-08-07 23:36:40","AP02SDTM":"2022-08-07 23:36:40","AP02EDTM":"2023-08-08 05:36:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-08","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":993,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.05491,"AVALU":"mg/L","BASE2":8.95923,"BASE":8.78014,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09568,"PCHG2":1.06797,"CHG":0.27477,"PCHG":3.1295,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-14 11:36:40","ADY":1010,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-143","SUBJID":"id-143","SITEID":"CHN-14","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.17717,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-07 11:36:40","TRTEDTM":"2023-08-08 05:36:40","TRT01SDTM":"2020-08-07 11:36:40","TRT01EDTM":"2022-08-07 23:36:40","TRT02SDTM":"2022-08-07 23:36:40","TRT02EDTM":"2023-08-08 05:36:40","AP01SDTM":"2020-08-07 11:36:40","AP01EDTM":"2022-08-07 23:36:40","AP02SDTM":"2022-08-07 23:36:40","AP02EDTM":"2023-08-08 05:36:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-08","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5868,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.874,"AVALU":"g/L","BASE2":2.874,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-24 11:36:40","ADY":321,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-143","SUBJID":"id-143","SITEID":"CHN-14","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.17717,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-07 11:36:40","TRTEDTM":"2023-08-08 05:36:40","TRT01SDTM":"2020-08-07 11:36:40","TRT01EDTM":"2022-08-07 23:36:40","TRT02SDTM":"2022-08-07 23:36:40","TRT02EDTM":"2023-08-08 05:36:40","AP01SDTM":"2020-08-07 11:36:40","AP01EDTM":"2022-08-07 23:36:40","AP02SDTM":"2022-08-07 23:36:40","AP02EDTM":"2023-08-08 05:36:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-08","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7896,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85656,"AVALU":"g/L","BASE2":2.874,"BASE":2.85656,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.01743,"PCHG2":-0.60655,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-03 11:36:40","ADY":361,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-143","SUBJID":"id-143","SITEID":"CHN-14","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.17717,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-07 11:36:40","TRTEDTM":"2023-08-08 05:36:40","TRT01SDTM":"2020-08-07 11:36:40","TRT01EDTM":"2022-08-07 23:36:40","TRT02SDTM":"2022-08-07 23:36:40","TRT02EDTM":"2023-08-08 05:36:40","AP01SDTM":"2020-08-07 11:36:40","AP01EDTM":"2022-08-07 23:36:40","AP02SDTM":"2022-08-07 23:36:40","AP02EDTM":"2023-08-08 05:36:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-08","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3955,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85739,"AVALU":"g/L","BASE2":2.874,"BASE":2.85656,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01661,"PCHG2":-0.57779,"CHG":0.00083,"PCHG":0.02894,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-22 11:36:40","ADY":592,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-143","SUBJID":"id-143","SITEID":"CHN-14","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.17717,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-07 11:36:40","TRTEDTM":"2023-08-08 05:36:40","TRT01SDTM":"2020-08-07 11:36:40","TRT01EDTM":"2022-08-07 23:36:40","TRT02SDTM":"2022-08-07 23:36:40","TRT02EDTM":"2023-08-08 05:36:40","AP01SDTM":"2020-08-07 11:36:40","AP01EDTM":"2022-08-07 23:36:40","AP02SDTM":"2022-08-07 23:36:40","AP02EDTM":"2023-08-08 05:36:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-08","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5350,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76312,"AVALU":"g/L","BASE2":2.874,"BASE":2.85656,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11088,"PCHG2":-3.85795,"CHG":-0.09344,"PCHG":-3.27124,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-24 11:36:40","ADY":594,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-143","SUBJID":"id-143","SITEID":"CHN-14","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.17717,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-07 11:36:40","TRTEDTM":"2023-08-08 05:36:40","TRT01SDTM":"2020-08-07 11:36:40","TRT01EDTM":"2022-08-07 23:36:40","TRT02SDTM":"2022-08-07 23:36:40","TRT02EDTM":"2023-08-08 05:36:40","AP01SDTM":"2020-08-07 11:36:40","AP01EDTM":"2022-08-07 23:36:40","AP02SDTM":"2022-08-07 23:36:40","AP02EDTM":"2023-08-08 05:36:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-08","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2747,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8554,"AVALU":"g/L","BASE2":2.874,"BASE":2.85656,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0186,"PCHG2":-0.64717,"CHG":-0.00117,"PCHG":-0.04086,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-03 11:36:40","ADY":604,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-143","SUBJID":"id-143","SITEID":"CHN-14","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.17717,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-07 11:36:40","TRTEDTM":"2023-08-08 05:36:40","TRT01SDTM":"2020-08-07 11:36:40","TRT01EDTM":"2022-08-07 23:36:40","TRT02SDTM":"2022-08-07 23:36:40","TRT02EDTM":"2023-08-08 05:36:40","AP01SDTM":"2020-08-07 11:36:40","AP01EDTM":"2022-08-07 23:36:40","AP02SDTM":"2022-08-07 23:36:40","AP02EDTM":"2023-08-08 05:36:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-08","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3628,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88861,"AVALU":"g/L","BASE2":2.874,"BASE":2.85656,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01461,"PCHG2":0.50848,"CHG":0.03205,"PCHG":1.12183,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-14 11:36:40","ADY":859,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-143","SUBJID":"id-143","SITEID":"CHN-14","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.17717,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-07 11:36:40","TRTEDTM":"2023-08-08 05:36:40","TRT01SDTM":"2020-08-07 11:36:40","TRT01EDTM":"2022-08-07 23:36:40","TRT02SDTM":"2022-08-07 23:36:40","TRT02EDTM":"2023-08-08 05:36:40","AP01SDTM":"2020-08-07 11:36:40","AP01EDTM":"2022-08-07 23:36:40","AP02SDTM":"2022-08-07 23:36:40","AP02EDTM":"2023-08-08 05:36:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-08","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":140,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03109,"AVALU":"g/L","BASE2":2.874,"BASE":2.85656,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1571,"PCHG2":5.46616,"CHG":0.17453,"PCHG":6.10977,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2023-05-14 11:36:40","ADY":1010,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-161","SUBJID":"id-161","SITEID":"CHN-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.56375,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-12 02:39:34","TRTEDTM":"2022-09-11 20:39:34","TRT01SDTM":"2019-09-12 02:39:34","TRT01EDTM":"2021-09-11 14:39:34","TRT02SDTM":"2021-09-11 14:39:34","TRT02EDTM":"2022-09-11 20:39:34","AP01SDTM":"2019-09-12 02:39:34","AP01EDTM":"2021-09-11 14:39:34","AP02SDTM":"2021-09-11 14:39:34","AP02EDTM":"2022-09-11 20:39:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-09-23","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3107,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.75387,"AVALU":"U/L","BASE2":5.75387,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-01-13 02:39:34","ADY":123,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-161","SUBJID":"id-161","SITEID":"CHN-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.56375,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-12 02:39:34","TRTEDTM":"2022-09-11 20:39:34","TRT01SDTM":"2019-09-12 02:39:34","TRT01EDTM":"2021-09-11 14:39:34","TRT02SDTM":"2021-09-11 14:39:34","TRT02EDTM":"2022-09-11 20:39:34","AP01SDTM":"2019-09-12 02:39:34","AP01EDTM":"2021-09-11 14:39:34","AP02SDTM":"2021-09-11 14:39:34","AP02EDTM":"2022-09-11 20:39:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-09-23","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8001,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.94175,"AVALU":"U/L","BASE2":5.75387,"BASE":13.94175,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":8.18787,"PCHG2":142.30193,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-15 02:39:34","ADY":125,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-161","SUBJID":"id-161","SITEID":"CHN-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.56375,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-12 02:39:34","TRTEDTM":"2022-09-11 20:39:34","TRT01SDTM":"2019-09-12 02:39:34","TRT01EDTM":"2021-09-11 14:39:34","TRT02SDTM":"2021-09-11 14:39:34","TRT02EDTM":"2022-09-11 20:39:34","AP01SDTM":"2019-09-12 02:39:34","AP01EDTM":"2021-09-11 14:39:34","AP02SDTM":"2021-09-11 14:39:34","AP02EDTM":"2022-09-11 20:39:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-09-23","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6714,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.08589,"AVALU":"U/L","BASE2":5.75387,"BASE":13.94175,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.66798,"PCHG2":-11.6093,"CHG":-8.85586,"PCHG":-63.52043,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-11-25 02:39:34","ADY":440,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-161","SUBJID":"id-161","SITEID":"CHN-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.56375,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-12 02:39:34","TRTEDTM":"2022-09-11 20:39:34","TRT01SDTM":"2019-09-12 02:39:34","TRT01EDTM":"2021-09-11 14:39:34","TRT02SDTM":"2021-09-11 14:39:34","TRT02EDTM":"2022-09-11 20:39:34","AP01SDTM":"2019-09-12 02:39:34","AP01EDTM":"2021-09-11 14:39:34","AP02SDTM":"2021-09-11 14:39:34","AP02EDTM":"2022-09-11 20:39:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-09-23","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7399,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.74007,"AVALU":"U/L","BASE2":5.75387,"BASE":13.94175,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":27.9862,"PCHG2":486.38879,"CHG":19.79832,"PCHG":142.00747,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-04 02:39:34","ADY":511,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-161","SUBJID":"id-161","SITEID":"CHN-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.56375,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-12 02:39:34","TRTEDTM":"2022-09-11 20:39:34","TRT01SDTM":"2019-09-12 02:39:34","TRT01EDTM":"2021-09-11 14:39:34","TRT02SDTM":"2021-09-11 14:39:34","TRT02EDTM":"2022-09-11 20:39:34","AP01SDTM":"2019-09-12 02:39:34","AP01EDTM":"2021-09-11 14:39:34","AP02SDTM":"2021-09-11 14:39:34","AP02EDTM":"2022-09-11 20:39:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-09-23","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4920,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.61237,"AVALU":"U/L","BASE2":5.75387,"BASE":13.94175,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":25.8585,"PCHG2":449.41028,"CHG":17.67063,"PCHG":126.74614,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-10 02:39:34","ADY":637,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-161","SUBJID":"id-161","SITEID":"CHN-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.56375,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-12 02:39:34","TRTEDTM":"2022-09-11 20:39:34","TRT01SDTM":"2019-09-12 02:39:34","TRT01EDTM":"2021-09-11 14:39:34","TRT02SDTM":"2021-09-11 14:39:34","TRT02EDTM":"2022-09-11 20:39:34","AP01SDTM":"2019-09-12 02:39:34","AP01EDTM":"2021-09-11 14:39:34","AP02SDTM":"2021-09-11 14:39:34","AP02EDTM":"2022-09-11 20:39:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-09-23","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":413,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.36832,"AVALU":"U/L","BASE2":5.75387,"BASE":13.94175,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.61445,"PCHG2":114.95646,"CHG":-1.57342,"PCHG":-11.2857,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-03 02:39:34","ADY":722,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-161","SUBJID":"id-161","SITEID":"CHN-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.56375,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-12 02:39:34","TRTEDTM":"2022-09-11 20:39:34","TRT01SDTM":"2019-09-12 02:39:34","TRT01EDTM":"2021-09-11 14:39:34","TRT02SDTM":"2021-09-11 14:39:34","TRT02EDTM":"2022-09-11 20:39:34","AP01SDTM":"2019-09-12 02:39:34","AP01EDTM":"2021-09-11 14:39:34","AP02SDTM":"2021-09-11 14:39:34","AP02EDTM":"2022-09-11 20:39:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-09-23","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1069,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.1673,"AVALU":"U/L","BASE2":5.75387,"BASE":13.94175,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.58657,"PCHG2":-10.19433,"CHG":-8.77444,"PCHG":-62.93646,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-02-03 02:39:34","ADY":875,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-161","SUBJID":"id-161","SITEID":"CHN-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.56375,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-12 02:39:34","TRTEDTM":"2022-09-11 20:39:34","TRT01SDTM":"2019-09-12 02:39:34","TRT01EDTM":"2021-09-11 14:39:34","TRT02SDTM":"2021-09-11 14:39:34","TRT02EDTM":"2022-09-11 20:39:34","AP01SDTM":"2019-09-12 02:39:34","AP01EDTM":"2021-09-11 14:39:34","AP02SDTM":"2021-09-11 14:39:34","AP02EDTM":"2022-09-11 20:39:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-09-23","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5069,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.74223,"AVALU":"mg/L","BASE2":9.74223,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-01-13 02:39:34","ADY":123,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-161","SUBJID":"id-161","SITEID":"CHN-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.56375,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-12 02:39:34","TRTEDTM":"2022-09-11 20:39:34","TRT01SDTM":"2019-09-12 02:39:34","TRT01EDTM":"2021-09-11 14:39:34","TRT02SDTM":"2021-09-11 14:39:34","TRT02EDTM":"2022-09-11 20:39:34","AP01SDTM":"2019-09-12 02:39:34","AP01EDTM":"2021-09-11 14:39:34","AP02SDTM":"2021-09-11 14:39:34","AP02EDTM":"2022-09-11 20:39:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-09-23","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3048,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.09625,"AVALU":"mg/L","BASE2":9.74223,"BASE":10.09625,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.35402,"PCHG2":3.63382,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2020-01-15 02:39:34","ADY":125,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-161","SUBJID":"id-161","SITEID":"CHN-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.56375,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-12 02:39:34","TRTEDTM":"2022-09-11 20:39:34","TRT01SDTM":"2019-09-12 02:39:34","TRT01EDTM":"2021-09-11 14:39:34","TRT02SDTM":"2021-09-11 14:39:34","TRT02EDTM":"2022-09-11 20:39:34","AP01SDTM":"2019-09-12 02:39:34","AP01EDTM":"2021-09-11 14:39:34","AP02SDTM":"2021-09-11 14:39:34","AP02EDTM":"2022-09-11 20:39:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-09-23","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2437,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.40607,"AVALU":"mg/L","BASE2":9.74223,"BASE":10.09625,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.33616,"PCHG2":-13.71516,"CHG":-1.69018,"PCHG":-16.74066,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-11-25 02:39:34","ADY":440,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-161","SUBJID":"id-161","SITEID":"CHN-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.56375,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-12 02:39:34","TRTEDTM":"2022-09-11 20:39:34","TRT01SDTM":"2019-09-12 02:39:34","TRT01EDTM":"2021-09-11 14:39:34","TRT02SDTM":"2021-09-11 14:39:34","TRT02EDTM":"2022-09-11 20:39:34","AP01SDTM":"2019-09-12 02:39:34","AP01EDTM":"2021-09-11 14:39:34","AP02SDTM":"2021-09-11 14:39:34","AP02EDTM":"2022-09-11 20:39:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-09-23","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5828,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.42931,"AVALU":"mg/L","BASE2":9.74223,"BASE":10.09625,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.31292,"PCHG2":-3.212,"CHG":-0.66694,"PCHG":-6.60577,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-02-04 02:39:34","ADY":511,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-161","SUBJID":"id-161","SITEID":"CHN-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.56375,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-12 02:39:34","TRTEDTM":"2022-09-11 20:39:34","TRT01SDTM":"2019-09-12 02:39:34","TRT01EDTM":"2021-09-11 14:39:34","TRT02SDTM":"2021-09-11 14:39:34","TRT02EDTM":"2022-09-11 20:39:34","AP01SDTM":"2019-09-12 02:39:34","AP01EDTM":"2021-09-11 14:39:34","AP02SDTM":"2021-09-11 14:39:34","AP02EDTM":"2022-09-11 20:39:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-09-23","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5020,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.4646,"AVALU":"mg/L","BASE2":9.74223,"BASE":10.09625,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.27764,"PCHG2":-33.64357,"CHG":-3.63165,"PCHG":-35.97029,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-1","BTOXGR":"3","ADTM":"2021-06-10 02:39:34","ADY":637,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-161","SUBJID":"id-161","SITEID":"CHN-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.56375,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-12 02:39:34","TRTEDTM":"2022-09-11 20:39:34","TRT01SDTM":"2019-09-12 02:39:34","TRT01EDTM":"2021-09-11 14:39:34","TRT02SDTM":"2021-09-11 14:39:34","TRT02EDTM":"2022-09-11 20:39:34","AP01SDTM":"2019-09-12 02:39:34","AP01EDTM":"2021-09-11 14:39:34","AP02SDTM":"2021-09-11 14:39:34","AP02EDTM":"2022-09-11 20:39:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-09-23","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8129,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.89822,"AVALU":"mg/L","BASE2":9.74223,"BASE":10.09625,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15599,"PCHG2":1.60114,"CHG":-0.19803,"PCHG":-1.9614,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-09-03 02:39:34","ADY":722,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-161","SUBJID":"id-161","SITEID":"CHN-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.56375,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-12 02:39:34","TRTEDTM":"2022-09-11 20:39:34","TRT01SDTM":"2019-09-12 02:39:34","TRT01EDTM":"2021-09-11 14:39:34","TRT02SDTM":"2021-09-11 14:39:34","TRT02EDTM":"2022-09-11 20:39:34","AP01SDTM":"2019-09-12 02:39:34","AP01EDTM":"2021-09-11 14:39:34","AP02SDTM":"2021-09-11 14:39:34","AP02EDTM":"2022-09-11 20:39:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-09-23","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5502,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.08754,"AVALU":"mg/L","BASE2":9.74223,"BASE":10.09625,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.65469,"PCHG2":-6.72013,"CHG":-1.00871,"PCHG":-9.9909,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-02-03 02:39:34","ADY":875,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-161","SUBJID":"id-161","SITEID":"CHN-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.56375,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-12 02:39:34","TRTEDTM":"2022-09-11 20:39:34","TRT01SDTM":"2019-09-12 02:39:34","TRT01EDTM":"2021-09-11 14:39:34","TRT02SDTM":"2021-09-11 14:39:34","TRT02EDTM":"2022-09-11 20:39:34","AP01SDTM":"2019-09-12 02:39:34","AP01EDTM":"2021-09-11 14:39:34","AP02SDTM":"2021-09-11 14:39:34","AP02EDTM":"2022-09-11 20:39:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-09-23","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1402,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93064,"AVALU":"g/L","BASE2":2.93064,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-13 02:39:34","ADY":123,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-161","SUBJID":"id-161","SITEID":"CHN-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.56375,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-12 02:39:34","TRTEDTM":"2022-09-11 20:39:34","TRT01SDTM":"2019-09-12 02:39:34","TRT01EDTM":"2021-09-11 14:39:34","TRT02SDTM":"2021-09-11 14:39:34","TRT02EDTM":"2022-09-11 20:39:34","AP01SDTM":"2019-09-12 02:39:34","AP01EDTM":"2021-09-11 14:39:34","AP02SDTM":"2021-09-11 14:39:34","AP02EDTM":"2022-09-11 20:39:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-09-23","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":187,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92959,"AVALU":"g/L","BASE2":2.93064,"BASE":2.92959,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.00105,"PCHG2":-0.03581,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-15 02:39:34","ADY":125,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-161","SUBJID":"id-161","SITEID":"CHN-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.56375,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-12 02:39:34","TRTEDTM":"2022-09-11 20:39:34","TRT01SDTM":"2019-09-12 02:39:34","TRT01EDTM":"2021-09-11 14:39:34","TRT02SDTM":"2021-09-11 14:39:34","TRT02EDTM":"2022-09-11 20:39:34","AP01SDTM":"2019-09-12 02:39:34","AP01EDTM":"2021-09-11 14:39:34","AP02SDTM":"2021-09-11 14:39:34","AP02EDTM":"2022-09-11 20:39:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-09-23","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6452,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90103,"AVALU":"g/L","BASE2":2.93064,"BASE":2.92959,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02961,"PCHG2":-1.01038,"CHG":-0.02856,"PCHG":-0.97492,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-25 02:39:34","ADY":440,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-161","SUBJID":"id-161","SITEID":"CHN-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.56375,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-12 02:39:34","TRTEDTM":"2022-09-11 20:39:34","TRT01SDTM":"2019-09-12 02:39:34","TRT01EDTM":"2021-09-11 14:39:34","TRT02SDTM":"2021-09-11 14:39:34","TRT02EDTM":"2022-09-11 20:39:34","AP01SDTM":"2019-09-12 02:39:34","AP01EDTM":"2021-09-11 14:39:34","AP02SDTM":"2021-09-11 14:39:34","AP02EDTM":"2022-09-11 20:39:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-09-23","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5015,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93223,"AVALU":"g/L","BASE2":2.93064,"BASE":2.92959,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00159,"PCHG2":0.05431,"CHG":0.00264,"PCHG":0.09015,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-04 02:39:34","ADY":511,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-161","SUBJID":"id-161","SITEID":"CHN-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.56375,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-12 02:39:34","TRTEDTM":"2022-09-11 20:39:34","TRT01SDTM":"2019-09-12 02:39:34","TRT01EDTM":"2021-09-11 14:39:34","TRT02SDTM":"2021-09-11 14:39:34","TRT02EDTM":"2022-09-11 20:39:34","AP01SDTM":"2019-09-12 02:39:34","AP01EDTM":"2021-09-11 14:39:34","AP02SDTM":"2021-09-11 14:39:34","AP02EDTM":"2022-09-11 20:39:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-09-23","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4341,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84905,"AVALU":"g/L","BASE2":2.93064,"BASE":2.92959,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08158,"PCHG2":-2.78384,"CHG":-0.08053,"PCHG":-2.74902,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-10 02:39:34","ADY":637,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-161","SUBJID":"id-161","SITEID":"CHN-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.56375,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-12 02:39:34","TRTEDTM":"2022-09-11 20:39:34","TRT01SDTM":"2019-09-12 02:39:34","TRT01EDTM":"2021-09-11 14:39:34","TRT02SDTM":"2021-09-11 14:39:34","TRT02EDTM":"2022-09-11 20:39:34","AP01SDTM":"2019-09-12 02:39:34","AP01EDTM":"2021-09-11 14:39:34","AP02SDTM":"2021-09-11 14:39:34","AP02EDTM":"2022-09-11 20:39:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-09-23","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":38,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97311,"AVALU":"g/L","BASE2":2.93064,"BASE":2.92959,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04247,"PCHG2":1.44915,"CHG":0.04352,"PCHG":1.4855,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-03 02:39:34","ADY":722,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-161","SUBJID":"id-161","SITEID":"CHN-14","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.56375,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-12 02:39:34","TRTEDTM":"2022-09-11 20:39:34","TRT01SDTM":"2019-09-12 02:39:34","TRT01EDTM":"2021-09-11 14:39:34","TRT02SDTM":"2021-09-11 14:39:34","TRT02EDTM":"2022-09-11 20:39:34","AP01SDTM":"2019-09-12 02:39:34","AP01EDTM":"2021-09-11 14:39:34","AP02SDTM":"2021-09-11 14:39:34","AP02EDTM":"2022-09-11 20:39:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-09-23","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2440,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85458,"AVALU":"g/L","BASE2":2.93064,"BASE":2.92959,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07606,"PCHG2":-2.59535,"CHG":-0.07501,"PCHG":-2.56046,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-03 02:39:34","ADY":875,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-168","SUBJID":"id-168","SITEID":"CHN-14","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.75487,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-25","TRTSDTM":"2019-05-29 13:19:29","TRTEDTM":"2022-05-29 07:19:29","TRT01SDTM":"2019-05-29 13:19:29","TRT01EDTM":"2021-05-29 01:19:29","TRT02SDTM":"2021-05-29 01:19:29","TRT02EDTM":"2022-05-29 07:19:29","AP01SDTM":"2019-05-29 13:19:29","AP01EDTM":"2021-05-29 01:19:29","AP02SDTM":"2021-05-29 01:19:29","AP02EDTM":"2022-05-29 07:19:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-29","EOSDY":1096,"LSTALVDT":"2022-06-08","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":932,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.81108,"AVALU":"U/L","BASE2":26.81108,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-3","ADTM":"2019-11-08 13:19:29","ADY":163,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-168","SUBJID":"id-168","SITEID":"CHN-14","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.75487,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-25","TRTSDTM":"2019-05-29 13:19:29","TRTEDTM":"2022-05-29 07:19:29","TRT01SDTM":"2019-05-29 13:19:29","TRT01EDTM":"2021-05-29 01:19:29","TRT02SDTM":"2021-05-29 01:19:29","TRT02EDTM":"2022-05-29 07:19:29","AP01SDTM":"2019-05-29 13:19:29","AP01EDTM":"2021-05-29 01:19:29","AP02SDTM":"2021-05-29 01:19:29","AP02EDTM":"2022-05-29 07:19:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-29","EOSDY":1096,"LSTALVDT":"2022-06-08","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7624,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.11373,"AVALU":"U/L","BASE2":26.81108,"BASE":5.11373,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-21.69735,"PCHG2":-80.92681,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2020-02-04 13:19:29","ADY":251,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-168","SUBJID":"id-168","SITEID":"CHN-14","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.75487,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-25","TRTSDTM":"2019-05-29 13:19:29","TRTEDTM":"2022-05-29 07:19:29","TRT01SDTM":"2019-05-29 13:19:29","TRT01EDTM":"2021-05-29 01:19:29","TRT02SDTM":"2021-05-29 01:19:29","TRT02EDTM":"2022-05-29 07:19:29","AP01SDTM":"2019-05-29 13:19:29","AP01EDTM":"2021-05-29 01:19:29","AP02SDTM":"2021-05-29 01:19:29","AP02EDTM":"2022-05-29 07:19:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-29","EOSDY":1096,"LSTALVDT":"2022-06-08","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3596,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.30593,"AVALU":"U/L","BASE2":26.81108,"BASE":5.11373,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-21.50515,"PCHG2":-80.20995,"CHG":0.1922,"PCHG":3.75844,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-3","ADTM":"2020-03-27 13:19:29","ADY":303,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-168","SUBJID":"id-168","SITEID":"CHN-14","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.75487,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-25","TRTSDTM":"2019-05-29 13:19:29","TRTEDTM":"2022-05-29 07:19:29","TRT01SDTM":"2019-05-29 13:19:29","TRT01EDTM":"2021-05-29 01:19:29","TRT02SDTM":"2021-05-29 01:19:29","TRT02EDTM":"2022-05-29 07:19:29","AP01SDTM":"2019-05-29 13:19:29","AP01EDTM":"2021-05-29 01:19:29","AP02SDTM":"2021-05-29 01:19:29","AP02EDTM":"2022-05-29 07:19:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-29","EOSDY":1096,"LSTALVDT":"2022-06-08","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8207,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.53879,"AVALU":"U/L","BASE2":26.81108,"BASE":5.11373,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.27228,"PCHG2":-42.04338,"CHG":10.42507,"PCHG":203.86426,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-03-01 13:19:29","ADY":642,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-168","SUBJID":"id-168","SITEID":"CHN-14","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.75487,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-25","TRTSDTM":"2019-05-29 13:19:29","TRTEDTM":"2022-05-29 07:19:29","TRT01SDTM":"2019-05-29 13:19:29","TRT01EDTM":"2021-05-29 01:19:29","TRT02SDTM":"2021-05-29 01:19:29","TRT02EDTM":"2022-05-29 07:19:29","AP01SDTM":"2019-05-29 13:19:29","AP01EDTM":"2021-05-29 01:19:29","AP02SDTM":"2021-05-29 01:19:29","AP02EDTM":"2022-05-29 07:19:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-29","EOSDY":1096,"LSTALVDT":"2022-06-08","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1189,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.51474,"AVALU":"U/L","BASE2":26.81108,"BASE":5.11373,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.29634,"PCHG2":-16.02449,"CHG":17.40101,"PCHG":340.28028,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-05-25 13:19:29","ADY":727,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-168","SUBJID":"id-168","SITEID":"CHN-14","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.75487,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-25","TRTSDTM":"2019-05-29 13:19:29","TRTEDTM":"2022-05-29 07:19:29","TRT01SDTM":"2019-05-29 13:19:29","TRT01EDTM":"2021-05-29 01:19:29","TRT02SDTM":"2021-05-29 01:19:29","TRT02EDTM":"2022-05-29 07:19:29","AP01SDTM":"2019-05-29 13:19:29","AP01EDTM":"2021-05-29 01:19:29","AP02SDTM":"2021-05-29 01:19:29","AP02EDTM":"2022-05-29 07:19:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-29","EOSDY":1096,"LSTALVDT":"2022-06-08","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7525,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":36.37404,"AVALU":"U/L","BASE2":26.81108,"BASE":5.11373,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.56296,"PCHG2":35.66796,"CHG":31.26031,"PCHG":611.3017,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-11-28 13:19:29","ADY":914,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-168","SUBJID":"id-168","SITEID":"CHN-14","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.75487,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-25","TRTSDTM":"2019-05-29 13:19:29","TRTEDTM":"2022-05-29 07:19:29","TRT01SDTM":"2019-05-29 13:19:29","TRT01EDTM":"2021-05-29 01:19:29","TRT02SDTM":"2021-05-29 01:19:29","TRT02EDTM":"2022-05-29 07:19:29","AP01SDTM":"2019-05-29 13:19:29","AP01EDTM":"2021-05-29 01:19:29","AP02SDTM":"2021-05-29 01:19:29","AP02EDTM":"2022-05-29 07:19:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-29","EOSDY":1096,"LSTALVDT":"2022-06-08","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1468,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.56726,"AVALU":"U/L","BASE2":26.81108,"BASE":5.11373,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.24382,"PCHG2":-15.82859,"CHG":17.45353,"PCHG":341.30735,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2022-02-03 13:19:29","ADY":981,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-168","SUBJID":"id-168","SITEID":"CHN-14","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.75487,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-25","TRTSDTM":"2019-05-29 13:19:29","TRTEDTM":"2022-05-29 07:19:29","TRT01SDTM":"2019-05-29 13:19:29","TRT01EDTM":"2021-05-29 01:19:29","TRT02SDTM":"2021-05-29 01:19:29","TRT02EDTM":"2022-05-29 07:19:29","AP01SDTM":"2019-05-29 13:19:29","AP01EDTM":"2021-05-29 01:19:29","AP02SDTM":"2021-05-29 01:19:29","AP02EDTM":"2022-05-29 07:19:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-29","EOSDY":1096,"LSTALVDT":"2022-06-08","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3514,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.68825,"AVALU":"mg/L","BASE2":8.68825,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-08 13:19:29","ADY":163,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-168","SUBJID":"id-168","SITEID":"CHN-14","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.75487,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-25","TRTSDTM":"2019-05-29 13:19:29","TRTEDTM":"2022-05-29 07:19:29","TRT01SDTM":"2019-05-29 13:19:29","TRT01EDTM":"2021-05-29 01:19:29","TRT02SDTM":"2021-05-29 01:19:29","TRT02EDTM":"2022-05-29 07:19:29","AP01SDTM":"2019-05-29 13:19:29","AP01EDTM":"2021-05-29 01:19:29","AP02SDTM":"2021-05-29 01:19:29","AP02EDTM":"2022-05-29 07:19:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-29","EOSDY":1096,"LSTALVDT":"2022-06-08","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2283,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.80149,"AVALU":"mg/L","BASE2":8.68825,"BASE":8.80149,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.11323,"PCHG2":1.30329,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-04 13:19:29","ADY":251,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-168","SUBJID":"id-168","SITEID":"CHN-14","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.75487,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-25","TRTSDTM":"2019-05-29 13:19:29","TRTEDTM":"2022-05-29 07:19:29","TRT01SDTM":"2019-05-29 13:19:29","TRT01EDTM":"2021-05-29 01:19:29","TRT02SDTM":"2021-05-29 01:19:29","TRT02EDTM":"2022-05-29 07:19:29","AP01SDTM":"2019-05-29 13:19:29","AP01EDTM":"2021-05-29 01:19:29","AP02SDTM":"2021-05-29 01:19:29","AP02EDTM":"2022-05-29 07:19:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-29","EOSDY":1096,"LSTALVDT":"2022-06-08","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3667,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.89661,"AVALU":"mg/L","BASE2":8.68825,"BASE":8.80149,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.20836,"PCHG2":13.90795,"CHG":1.09512,"PCHG":12.44249,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-27 13:19:29","ADY":303,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-168","SUBJID":"id-168","SITEID":"CHN-14","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.75487,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-25","TRTSDTM":"2019-05-29 13:19:29","TRTEDTM":"2022-05-29 07:19:29","TRT01SDTM":"2019-05-29 13:19:29","TRT01EDTM":"2021-05-29 01:19:29","TRT02SDTM":"2021-05-29 01:19:29","TRT02EDTM":"2022-05-29 07:19:29","AP01SDTM":"2019-05-29 13:19:29","AP01EDTM":"2021-05-29 01:19:29","AP02SDTM":"2021-05-29 01:19:29","AP02EDTM":"2022-05-29 07:19:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-29","EOSDY":1096,"LSTALVDT":"2022-06-08","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8362,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.31635,"AVALU":"mg/L","BASE2":8.68825,"BASE":8.80149,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.37191,"PCHG2":-15.79038,"CHG":-1.48514,"PCHG":-16.87376,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-03-01 13:19:29","ADY":642,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-168","SUBJID":"id-168","SITEID":"CHN-14","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.75487,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-25","TRTSDTM":"2019-05-29 13:19:29","TRTEDTM":"2022-05-29 07:19:29","TRT01SDTM":"2019-05-29 13:19:29","TRT01EDTM":"2021-05-29 01:19:29","TRT02SDTM":"2021-05-29 01:19:29","TRT02EDTM":"2022-05-29 07:19:29","AP01SDTM":"2019-05-29 13:19:29","AP01EDTM":"2021-05-29 01:19:29","AP02SDTM":"2021-05-29 01:19:29","AP02EDTM":"2022-05-29 07:19:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-29","EOSDY":1096,"LSTALVDT":"2022-06-08","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3543,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.24029,"AVALU":"mg/L","BASE2":8.68825,"BASE":8.80149,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.55203,"PCHG2":29.37335,"CHG":2.4388,"PCHG":27.70893,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-05-25 13:19:29","ADY":727,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-168","SUBJID":"id-168","SITEID":"CHN-14","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.75487,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-25","TRTSDTM":"2019-05-29 13:19:29","TRTEDTM":"2022-05-29 07:19:29","TRT01SDTM":"2019-05-29 13:19:29","TRT01EDTM":"2021-05-29 01:19:29","TRT02SDTM":"2021-05-29 01:19:29","TRT02EDTM":"2022-05-29 07:19:29","AP01SDTM":"2019-05-29 13:19:29","AP01EDTM":"2021-05-29 01:19:29","AP02SDTM":"2021-05-29 01:19:29","AP02EDTM":"2022-05-29 07:19:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-29","EOSDY":1096,"LSTALVDT":"2022-06-08","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3842,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.7146,"AVALU":"mg/L","BASE2":8.68825,"BASE":8.80149,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.02635,"PCHG2":11.81309,"CHG":0.91312,"PCHG":10.37458,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-28 13:19:29","ADY":914,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-168","SUBJID":"id-168","SITEID":"CHN-14","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.75487,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-25","TRTSDTM":"2019-05-29 13:19:29","TRTEDTM":"2022-05-29 07:19:29","TRT01SDTM":"2019-05-29 13:19:29","TRT01EDTM":"2021-05-29 01:19:29","TRT02SDTM":"2021-05-29 01:19:29","TRT02EDTM":"2022-05-29 07:19:29","AP01SDTM":"2019-05-29 13:19:29","AP01EDTM":"2021-05-29 01:19:29","AP02SDTM":"2021-05-29 01:19:29","AP02EDTM":"2022-05-29 07:19:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-29","EOSDY":1096,"LSTALVDT":"2022-06-08","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8223,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.45724,"AVALU":"mg/L","BASE2":8.68825,"BASE":8.80149,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.76899,"PCHG2":8.85088,"CHG":0.65575,"PCHG":7.45049,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-03 13:19:29","ADY":981,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-168","SUBJID":"id-168","SITEID":"CHN-14","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.75487,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-25","TRTSDTM":"2019-05-29 13:19:29","TRTEDTM":"2022-05-29 07:19:29","TRT01SDTM":"2019-05-29 13:19:29","TRT01EDTM":"2021-05-29 01:19:29","TRT02SDTM":"2021-05-29 01:19:29","TRT02EDTM":"2022-05-29 07:19:29","AP01SDTM":"2019-05-29 13:19:29","AP01EDTM":"2021-05-29 01:19:29","AP02SDTM":"2021-05-29 01:19:29","AP02EDTM":"2022-05-29 07:19:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-29","EOSDY":1096,"LSTALVDT":"2022-06-08","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3415,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82927,"AVALU":"g/L","BASE2":2.82927,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-08 13:19:29","ADY":163,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-168","SUBJID":"id-168","SITEID":"CHN-14","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.75487,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-25","TRTSDTM":"2019-05-29 13:19:29","TRTEDTM":"2022-05-29 07:19:29","TRT01SDTM":"2019-05-29 13:19:29","TRT01EDTM":"2021-05-29 01:19:29","TRT02SDTM":"2021-05-29 01:19:29","TRT02EDTM":"2022-05-29 07:19:29","AP01SDTM":"2019-05-29 13:19:29","AP01EDTM":"2021-05-29 01:19:29","AP02SDTM":"2021-05-29 01:19:29","AP02EDTM":"2022-05-29 07:19:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-29","EOSDY":1096,"LSTALVDT":"2022-06-08","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8039,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83583,"AVALU":"g/L","BASE2":2.82927,"BASE":2.83583,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.00656,"PCHG2":0.23174,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-04 13:19:29","ADY":251,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-168","SUBJID":"id-168","SITEID":"CHN-14","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.75487,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-25","TRTSDTM":"2019-05-29 13:19:29","TRTEDTM":"2022-05-29 07:19:29","TRT01SDTM":"2019-05-29 13:19:29","TRT01EDTM":"2021-05-29 01:19:29","TRT02SDTM":"2021-05-29 01:19:29","TRT02EDTM":"2022-05-29 07:19:29","AP01SDTM":"2019-05-29 13:19:29","AP01EDTM":"2021-05-29 01:19:29","AP02SDTM":"2021-05-29 01:19:29","AP02EDTM":"2022-05-29 07:19:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-29","EOSDY":1096,"LSTALVDT":"2022-06-08","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":573,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78096,"AVALU":"g/L","BASE2":2.82927,"BASE":2.83583,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04831,"PCHG2":-1.70736,"CHG":-0.05486,"PCHG":-1.93462,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-27 13:19:29","ADY":303,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-168","SUBJID":"id-168","SITEID":"CHN-14","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.75487,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-25","TRTSDTM":"2019-05-29 13:19:29","TRTEDTM":"2022-05-29 07:19:29","TRT01SDTM":"2019-05-29 13:19:29","TRT01EDTM":"2021-05-29 01:19:29","TRT02SDTM":"2021-05-29 01:19:29","TRT02EDTM":"2022-05-29 07:19:29","AP01SDTM":"2019-05-29 13:19:29","AP01EDTM":"2021-05-29 01:19:29","AP02SDTM":"2021-05-29 01:19:29","AP02EDTM":"2022-05-29 07:19:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-29","EOSDY":1096,"LSTALVDT":"2022-06-08","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6554,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98063,"AVALU":"g/L","BASE2":2.82927,"BASE":2.83583,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15136,"PCHG2":5.3498,"CHG":0.1448,"PCHG":5.10623,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-01 13:19:29","ADY":642,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-168","SUBJID":"id-168","SITEID":"CHN-14","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.75487,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-25","TRTSDTM":"2019-05-29 13:19:29","TRTEDTM":"2022-05-29 07:19:29","TRT01SDTM":"2019-05-29 13:19:29","TRT01EDTM":"2021-05-29 01:19:29","TRT02SDTM":"2021-05-29 01:19:29","TRT02EDTM":"2022-05-29 07:19:29","AP01SDTM":"2019-05-29 13:19:29","AP01EDTM":"2021-05-29 01:19:29","AP02SDTM":"2021-05-29 01:19:29","AP02EDTM":"2022-05-29 07:19:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-29","EOSDY":1096,"LSTALVDT":"2022-06-08","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1445,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94584,"AVALU":"g/L","BASE2":2.82927,"BASE":2.83583,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11657,"PCHG2":4.12008,"CHG":0.11001,"PCHG":3.87935,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-25 13:19:29","ADY":727,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-168","SUBJID":"id-168","SITEID":"CHN-14","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.75487,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-25","TRTSDTM":"2019-05-29 13:19:29","TRTEDTM":"2022-05-29 07:19:29","TRT01SDTM":"2019-05-29 13:19:29","TRT01EDTM":"2021-05-29 01:19:29","TRT02SDTM":"2021-05-29 01:19:29","TRT02EDTM":"2022-05-29 07:19:29","AP01SDTM":"2019-05-29 13:19:29","AP01EDTM":"2021-05-29 01:19:29","AP02SDTM":"2021-05-29 01:19:29","AP02EDTM":"2022-05-29 07:19:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-29","EOSDY":1096,"LSTALVDT":"2022-06-08","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3335,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90973,"AVALU":"g/L","BASE2":2.82927,"BASE":2.83583,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08046,"PCHG2":2.84388,"CHG":0.0739,"PCHG":2.6061,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-28 13:19:29","ADY":914,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-168","SUBJID":"id-168","SITEID":"CHN-14","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.75487,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-25","TRTSDTM":"2019-05-29 13:19:29","TRTEDTM":"2022-05-29 07:19:29","TRT01SDTM":"2019-05-29 13:19:29","TRT01EDTM":"2021-05-29 01:19:29","TRT02SDTM":"2021-05-29 01:19:29","TRT02EDTM":"2022-05-29 07:19:29","AP01SDTM":"2019-05-29 13:19:29","AP01EDTM":"2021-05-29 01:19:29","AP02SDTM":"2021-05-29 01:19:29","AP02EDTM":"2022-05-29 07:19:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-29","EOSDY":1096,"LSTALVDT":"2022-06-08","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7589,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7545,"AVALU":"g/L","BASE2":2.82927,"BASE":2.83583,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07477,"PCHG2":-2.64288,"CHG":-0.08133,"PCHG":-2.86798,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-03 13:19:29","ADY":981,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-228","SUBJID":"id-228","SITEID":"CHN-14","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.31115,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-14","TRTSDTM":"2019-10-18 12:42:48","TRT01SDTM":"2019-10-18 12:42:48","AP01SDTM":"2019-10-18 12:42:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7656,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.26436,"AVALU":"U/L","BASE2":17.26436,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-16 12:42:48","ADY":121,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-228","SUBJID":"id-228","SITEID":"CHN-14","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.31115,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-14","TRTSDTM":"2019-10-18 12:42:48","TRT01SDTM":"2019-10-18 12:42:48","AP01SDTM":"2019-10-18 12:42:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2353,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.24392,"AVALU":"U/L","BASE2":17.26436,"BASE":29.24392,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":11.97957,"PCHG2":69.38902,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-19 12:42:48","ADY":245,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-228","SUBJID":"id-228","SITEID":"CHN-14","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.31115,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-14","TRTSDTM":"2019-10-18 12:42:48","TRT01SDTM":"2019-10-18 12:42:48","AP01SDTM":"2019-10-18 12:42:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":299,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.64413,"AVALU":"U/L","BASE2":17.26436,"BASE":29.24392,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.62022,"PCHG2":-49.93075,"CHG":-20.59979,"PCHG":-70.44127,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-22 12:42:48","ADY":309,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-228","SUBJID":"id-228","SITEID":"CHN-14","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.31115,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-14","TRTSDTM":"2019-10-18 12:42:48","TRT01SDTM":"2019-10-18 12:42:48","AP01SDTM":"2019-10-18 12:42:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7840,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.72841,"AVALU":"U/L","BASE2":17.26436,"BASE":29.24392,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.53595,"PCHG2":-14.68892,"CHG":-14.51552,"PCHG":-49.63601,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-24 12:42:48","ADY":342,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-228","SUBJID":"id-228","SITEID":"CHN-14","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.31115,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-14","TRTSDTM":"2019-10-18 12:42:48","TRT01SDTM":"2019-10-18 12:42:48","AP01SDTM":"2019-10-18 12:42:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4692,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.653,"AVALU":"U/L","BASE2":17.26436,"BASE":29.24392,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.38864,"PCHG2":89.13532,"CHG":3.40907,"PCHG":11.65737,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-20 12:42:48","ADY":399,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-228","SUBJID":"id-228","SITEID":"CHN-14","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.31115,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-14","TRTSDTM":"2019-10-18 12:42:48","TRT01SDTM":"2019-10-18 12:42:48","AP01SDTM":"2019-10-18 12:42:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3994,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.9417,"AVALU":"U/L","BASE2":17.26436,"BASE":29.24392,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.32266,"PCHG2":-42.41488,"CHG":-19.30222,"PCHG":-66.00422,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-09 12:42:48","ADY":418,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-228","SUBJID":"id-228","SITEID":"CHN-14","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.31115,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-14","TRTSDTM":"2019-10-18 12:42:48","TRT01SDTM":"2019-10-18 12:42:48","AP01SDTM":"2019-10-18 12:42:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":90,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.00724,"AVALU":"U/L","BASE2":17.26436,"BASE":29.24392,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.25712,"PCHG2":-99.95807,"CHG":-29.23668,"PCHG":-99.97524,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-01-08 12:42:48","ADY":448,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-228","SUBJID":"id-228","SITEID":"CHN-14","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.31115,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-14","TRTSDTM":"2019-10-18 12:42:48","TRT01SDTM":"2019-10-18 12:42:48","AP01SDTM":"2019-10-18 12:42:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":850,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.11882,"AVALU":"mg/L","BASE2":9.11882,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-02-16 12:42:48","ADY":121,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-228","SUBJID":"id-228","SITEID":"CHN-14","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.31115,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-14","TRTSDTM":"2019-10-18 12:42:48","TRT01SDTM":"2019-10-18 12:42:48","AP01SDTM":"2019-10-18 12:42:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":328,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.10827,"AVALU":"mg/L","BASE2":9.11882,"BASE":10.10827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.98945,"PCHG2":10.85069,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2020-06-19 12:42:48","ADY":245,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-228","SUBJID":"id-228","SITEID":"CHN-14","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.31115,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-14","TRTSDTM":"2019-10-18 12:42:48","TRT01SDTM":"2019-10-18 12:42:48","AP01SDTM":"2019-10-18 12:42:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1572,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.17584,"AVALU":"mg/L","BASE2":9.11882,"BASE":10.10827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.05702,"PCHG2":11.59164,"CHG":0.06757,"PCHG":0.66843,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"1","BTOXGR":"3","ADTM":"2020-08-22 12:42:48","ADY":309,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-228","SUBJID":"id-228","SITEID":"CHN-14","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.31115,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-14","TRTSDTM":"2019-10-18 12:42:48","TRT01SDTM":"2019-10-18 12:42:48","AP01SDTM":"2019-10-18 12:42:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5370,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.37193,"AVALU":"mg/L","BASE2":9.11882,"BASE":10.10827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.74689,"PCHG2":-8.1906,"CHG":-1.73634,"PCHG":-17.17742,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-09-24 12:42:48","ADY":342,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-228","SUBJID":"id-228","SITEID":"CHN-14","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.31115,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-14","TRTSDTM":"2019-10-18 12:42:48","TRT01SDTM":"2019-10-18 12:42:48","AP01SDTM":"2019-10-18 12:42:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8325,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.79252,"AVALU":"mg/L","BASE2":9.11882,"BASE":10.10827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.6737,"PCHG2":7.38804,"CHG":-0.31575,"PCHG":-3.1237,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-11-20 12:42:48","ADY":399,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-228","SUBJID":"id-228","SITEID":"CHN-14","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.31115,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-14","TRTSDTM":"2019-10-18 12:42:48","TRT01SDTM":"2019-10-18 12:42:48","AP01SDTM":"2019-10-18 12:42:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6962,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.6649,"AVALU":"mg/L","BASE2":9.11882,"BASE":10.10827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.45392,"PCHG2":-4.97784,"CHG":-1.44337,"PCHG":-14.27914,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-12-09 12:42:48","ADY":418,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-228","SUBJID":"id-228","SITEID":"CHN-14","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.31115,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-14","TRTSDTM":"2019-10-18 12:42:48","TRT01SDTM":"2019-10-18 12:42:48","AP01SDTM":"2019-10-18 12:42:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2306,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.51676,"AVALU":"mg/L","BASE2":9.11882,"BASE":10.10827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.60206,"PCHG2":-17.56869,"CHG":-2.59151,"PCHG":-25.63753,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-1","BTOXGR":"3","ADTM":"2021-01-08 12:42:48","ADY":448,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-228","SUBJID":"id-228","SITEID":"CHN-14","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.31115,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-14","TRTSDTM":"2019-10-18 12:42:48","TRT01SDTM":"2019-10-18 12:42:48","AP01SDTM":"2019-10-18 12:42:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4242,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97955,"AVALU":"g/L","BASE2":2.97955,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-16 12:42:48","ADY":121,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-228","SUBJID":"id-228","SITEID":"CHN-14","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.31115,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-14","TRTSDTM":"2019-10-18 12:42:48","TRT01SDTM":"2019-10-18 12:42:48","AP01SDTM":"2019-10-18 12:42:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7288,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9063,"AVALU":"g/L","BASE2":2.97955,"BASE":2.9063,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.07326,"PCHG2":-2.45864,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-19 12:42:48","ADY":245,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-228","SUBJID":"id-228","SITEID":"CHN-14","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.31115,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-14","TRTSDTM":"2019-10-18 12:42:48","TRT01SDTM":"2019-10-18 12:42:48","AP01SDTM":"2019-10-18 12:42:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6729,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93096,"AVALU":"g/L","BASE2":2.97955,"BASE":2.9063,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04859,"PCHG2":-1.63084,"CHG":0.02466,"PCHG":0.84867,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-22 12:42:48","ADY":309,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-228","SUBJID":"id-228","SITEID":"CHN-14","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.31115,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-14","TRTSDTM":"2019-10-18 12:42:48","TRT01SDTM":"2019-10-18 12:42:48","AP01SDTM":"2019-10-18 12:42:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6396,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90476,"AVALU":"g/L","BASE2":2.97955,"BASE":2.9063,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07479,"PCHG2":-2.5101,"CHG":-0.00153,"PCHG":-0.05276,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-24 12:42:48","ADY":342,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-228","SUBJID":"id-228","SITEID":"CHN-14","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.31115,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-14","TRTSDTM":"2019-10-18 12:42:48","TRT01SDTM":"2019-10-18 12:42:48","AP01SDTM":"2019-10-18 12:42:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2181,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83417,"AVALU":"g/L","BASE2":2.97955,"BASE":2.9063,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14538,"PCHG2":-4.87928,"CHG":-0.07212,"PCHG":-2.48165,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-20 12:42:48","ADY":399,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-228","SUBJID":"id-228","SITEID":"CHN-14","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.31115,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-14","TRTSDTM":"2019-10-18 12:42:48","TRT01SDTM":"2019-10-18 12:42:48","AP01SDTM":"2019-10-18 12:42:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5866,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78834,"AVALU":"g/L","BASE2":2.97955,"BASE":2.9063,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19121,"PCHG2":-6.41756,"CHG":-0.11796,"PCHG":-4.05871,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-09 12:42:48","ADY":418,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-228","SUBJID":"id-228","SITEID":"CHN-14","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.31115,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-14","TRTSDTM":"2019-10-18 12:42:48","TRT01SDTM":"2019-10-18 12:42:48","AP01SDTM":"2019-10-18 12:42:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6388,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95413,"AVALU":"g/L","BASE2":2.97955,"BASE":2.9063,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02542,"PCHG2":-0.85309,"CHG":0.04784,"PCHG":1.64602,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-08 12:42:48","ADY":448,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-305","SUBJID":"id-305","SITEID":"CHN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.83617,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-20","TRTSDTM":"2021-01-23 21:47:21","TRTEDTM":"2022-02-18 17:51:42","TRT01SDTM":"2021-01-23 21:47:21","TRT01EDTM":"2021-02-18 11:51:42","TRT02SDTM":"2021-02-18 11:51:42","TRT02EDTM":"2022-02-18 17:51:42","AP01SDTM":"2021-01-23 21:47:21","AP01EDTM":"2021-02-18 11:51:42","AP02SDTM":"2021-02-18 11:51:42","AP02EDTM":"2022-02-18 17:51:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":391,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":406,"ADTHAUT":"No","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3855,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.91669,"AVALU":"U/L","BASE2":28.91669,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-12 21:47:21","ADY":48,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-305","SUBJID":"id-305","SITEID":"CHN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.83617,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-20","TRTSDTM":"2021-01-23 21:47:21","TRTEDTM":"2022-02-18 17:51:42","TRT01SDTM":"2021-01-23 21:47:21","TRT01EDTM":"2021-02-18 11:51:42","TRT02SDTM":"2021-02-18 11:51:42","TRT02EDTM":"2022-02-18 17:51:42","AP01SDTM":"2021-01-23 21:47:21","AP01EDTM":"2021-02-18 11:51:42","AP02SDTM":"2021-02-18 11:51:42","AP02EDTM":"2022-02-18 17:51:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":391,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":406,"ADTHAUT":"No","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6509,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.51778,"AVALU":"U/L","BASE2":28.91669,"BASE":19.51778,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-9.39891,"PCHG2":-32.50341,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-27 21:47:21","ADY":155,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-305","SUBJID":"id-305","SITEID":"CHN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.83617,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-20","TRTSDTM":"2021-01-23 21:47:21","TRTEDTM":"2022-02-18 17:51:42","TRT01SDTM":"2021-01-23 21:47:21","TRT01EDTM":"2021-02-18 11:51:42","TRT02SDTM":"2021-02-18 11:51:42","TRT02EDTM":"2022-02-18 17:51:42","AP01SDTM":"2021-01-23 21:47:21","AP01EDTM":"2021-02-18 11:51:42","AP02SDTM":"2021-02-18 11:51:42","AP02EDTM":"2022-02-18 17:51:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":391,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":406,"ADTHAUT":"No","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3040,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":36.99127,"AVALU":"U/L","BASE2":28.91669,"BASE":19.51778,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.07458,"PCHG2":27.92361,"CHG":17.4735,"PCHG":89.52605,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-04 21:47:21","ADY":224,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-305","SUBJID":"id-305","SITEID":"CHN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.83617,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-20","TRTSDTM":"2021-01-23 21:47:21","TRTEDTM":"2022-02-18 17:51:42","TRT01SDTM":"2021-01-23 21:47:21","TRT01EDTM":"2021-02-18 11:51:42","TRT02SDTM":"2021-02-18 11:51:42","TRT02EDTM":"2022-02-18 17:51:42","AP01SDTM":"2021-01-23 21:47:21","AP01EDTM":"2021-02-18 11:51:42","AP02SDTM":"2021-02-18 11:51:42","AP02EDTM":"2022-02-18 17:51:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":391,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":406,"ADTHAUT":"No","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2999,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.11729,"AVALU":"U/L","BASE2":28.91669,"BASE":19.51778,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.79939,"PCHG2":-58.09584,"CHG":-7.40048,"PCHG":-37.91663,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-23 21:47:21","ADY":273,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-305","SUBJID":"id-305","SITEID":"CHN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.83617,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-20","TRTSDTM":"2021-01-23 21:47:21","TRTEDTM":"2022-02-18 17:51:42","TRT01SDTM":"2021-01-23 21:47:21","TRT01EDTM":"2021-02-18 11:51:42","TRT02SDTM":"2021-02-18 11:51:42","TRT02EDTM":"2022-02-18 17:51:42","AP01SDTM":"2021-01-23 21:47:21","AP01EDTM":"2021-02-18 11:51:42","AP02SDTM":"2021-02-18 11:51:42","AP02EDTM":"2022-02-18 17:51:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":391,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":406,"ADTHAUT":"No","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3746,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.51694,"AVALU":"U/L","BASE2":28.91669,"BASE":19.51778,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.39975,"PCHG2":-32.5063,"CHG":-0.00083,"PCHG":-0.00427,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-09 21:47:21","ADY":320,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-305","SUBJID":"id-305","SITEID":"CHN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.83617,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-20","TRTSDTM":"2021-01-23 21:47:21","TRTEDTM":"2022-02-18 17:51:42","TRT01SDTM":"2021-01-23 21:47:21","TRT01EDTM":"2021-02-18 11:51:42","TRT02SDTM":"2021-02-18 11:51:42","TRT02EDTM":"2022-02-18 17:51:42","AP01SDTM":"2021-01-23 21:47:21","AP01EDTM":"2021-02-18 11:51:42","AP02SDTM":"2021-02-18 11:51:42","AP02EDTM":"2022-02-18 17:51:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":391,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":406,"ADTHAUT":"No","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2056,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.07245,"AVALU":"U/L","BASE2":28.91669,"BASE":19.51778,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.84424,"PCHG2":-61.70915,"CHG":-8.44533,"PCHG":-43.26995,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-08 21:47:21","ADY":350,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-305","SUBJID":"id-305","SITEID":"CHN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.83617,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-20","TRTSDTM":"2021-01-23 21:47:21","TRTEDTM":"2022-02-18 17:51:42","TRT01SDTM":"2021-01-23 21:47:21","TRT01EDTM":"2021-02-18 11:51:42","TRT02SDTM":"2021-02-18 11:51:42","TRT02EDTM":"2022-02-18 17:51:42","AP01SDTM":"2021-01-23 21:47:21","AP01EDTM":"2021-02-18 11:51:42","AP02SDTM":"2021-02-18 11:51:42","AP02EDTM":"2022-02-18 17:51:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":391,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":406,"ADTHAUT":"No","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5688,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.96194,"AVALU":"U/L","BASE2":28.91669,"BASE":19.51778,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.95475,"PCHG2":-37.88384,"CHG":-1.55584,"PCHG":-7.97141,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-04 21:47:21","ADY":377,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-305","SUBJID":"id-305","SITEID":"CHN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.83617,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-20","TRTSDTM":"2021-01-23 21:47:21","TRTEDTM":"2022-02-18 17:51:42","TRT01SDTM":"2021-01-23 21:47:21","TRT01EDTM":"2021-02-18 11:51:42","TRT02SDTM":"2021-02-18 11:51:42","TRT02EDTM":"2022-02-18 17:51:42","AP01SDTM":"2021-01-23 21:47:21","AP01EDTM":"2021-02-18 11:51:42","AP02SDTM":"2021-02-18 11:51:42","AP02EDTM":"2022-02-18 17:51:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":391,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":406,"ADTHAUT":"No","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4712,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.13023,"AVALU":"mg/L","BASE2":9.13023,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-12 21:47:21","ADY":48,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-305","SUBJID":"id-305","SITEID":"CHN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.83617,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-20","TRTSDTM":"2021-01-23 21:47:21","TRTEDTM":"2022-02-18 17:51:42","TRT01SDTM":"2021-01-23 21:47:21","TRT01EDTM":"2021-02-18 11:51:42","TRT02SDTM":"2021-02-18 11:51:42","TRT02EDTM":"2022-02-18 17:51:42","AP01SDTM":"2021-01-23 21:47:21","AP01EDTM":"2021-02-18 11:51:42","AP02SDTM":"2021-02-18 11:51:42","AP02EDTM":"2022-02-18 17:51:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":391,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":406,"ADTHAUT":"No","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3775,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.44601,"AVALU":"mg/L","BASE2":9.13023,"BASE":9.44601,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.31578,"PCHG2":3.45862,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-27 21:47:21","ADY":155,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-305","SUBJID":"id-305","SITEID":"CHN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.83617,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-20","TRTSDTM":"2021-01-23 21:47:21","TRTEDTM":"2022-02-18 17:51:42","TRT01SDTM":"2021-01-23 21:47:21","TRT01EDTM":"2021-02-18 11:51:42","TRT02SDTM":"2021-02-18 11:51:42","TRT02EDTM":"2022-02-18 17:51:42","AP01SDTM":"2021-01-23 21:47:21","AP01EDTM":"2021-02-18 11:51:42","AP02SDTM":"2021-02-18 11:51:42","AP02EDTM":"2022-02-18 17:51:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":391,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":406,"ADTHAUT":"No","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7950,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.80517,"AVALU":"mg/L","BASE2":9.13023,"BASE":9.44601,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.67493,"PCHG2":7.3923,"CHG":0.35915,"PCHG":3.80218,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-04 21:47:21","ADY":224,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-305","SUBJID":"id-305","SITEID":"CHN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.83617,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-20","TRTSDTM":"2021-01-23 21:47:21","TRTEDTM":"2022-02-18 17:51:42","TRT01SDTM":"2021-01-23 21:47:21","TRT01EDTM":"2021-02-18 11:51:42","TRT02SDTM":"2021-02-18 11:51:42","TRT02EDTM":"2022-02-18 17:51:42","AP01SDTM":"2021-01-23 21:47:21","AP01EDTM":"2021-02-18 11:51:42","AP02SDTM":"2021-02-18 11:51:42","AP02EDTM":"2022-02-18 17:51:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":391,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":406,"ADTHAUT":"No","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":675,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.26174,"AVALU":"mg/L","BASE2":9.13023,"BASE":9.44601,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13151,"PCHG2":1.4404,"CHG":-0.18427,"PCHG":-1.95075,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-23 21:47:21","ADY":273,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-305","SUBJID":"id-305","SITEID":"CHN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.83617,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-20","TRTSDTM":"2021-01-23 21:47:21","TRTEDTM":"2022-02-18 17:51:42","TRT01SDTM":"2021-01-23 21:47:21","TRT01EDTM":"2021-02-18 11:51:42","TRT02SDTM":"2021-02-18 11:51:42","TRT02EDTM":"2022-02-18 17:51:42","AP01SDTM":"2021-01-23 21:47:21","AP01EDTM":"2021-02-18 11:51:42","AP02SDTM":"2021-02-18 11:51:42","AP02EDTM":"2022-02-18 17:51:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":391,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":406,"ADTHAUT":"No","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5922,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.81813,"AVALU":"mg/L","BASE2":9.13023,"BASE":9.44601,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.3121,"PCHG2":-14.37096,"CHG":-1.62788,"PCHG":-17.23354,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-12-09 21:47:21","ADY":320,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-305","SUBJID":"id-305","SITEID":"CHN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.83617,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-20","TRTSDTM":"2021-01-23 21:47:21","TRTEDTM":"2022-02-18 17:51:42","TRT01SDTM":"2021-01-23 21:47:21","TRT01EDTM":"2021-02-18 11:51:42","TRT02SDTM":"2021-02-18 11:51:42","TRT02EDTM":"2022-02-18 17:51:42","AP01SDTM":"2021-01-23 21:47:21","AP01EDTM":"2021-02-18 11:51:42","AP02SDTM":"2021-02-18 11:51:42","AP02EDTM":"2022-02-18 17:51:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":391,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":406,"ADTHAUT":"No","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6574,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.70867,"AVALU":"mg/L","BASE2":9.13023,"BASE":9.44601,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.42156,"PCHG2":-4.6172,"CHG":-0.73734,"PCHG":-7.80584,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-08 21:47:21","ADY":350,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-305","SUBJID":"id-305","SITEID":"CHN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.83617,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-20","TRTSDTM":"2021-01-23 21:47:21","TRTEDTM":"2022-02-18 17:51:42","TRT01SDTM":"2021-01-23 21:47:21","TRT01EDTM":"2021-02-18 11:51:42","TRT02SDTM":"2021-02-18 11:51:42","TRT02EDTM":"2022-02-18 17:51:42","AP01SDTM":"2021-01-23 21:47:21","AP01EDTM":"2021-02-18 11:51:42","AP02SDTM":"2021-02-18 11:51:42","AP02EDTM":"2022-02-18 17:51:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":391,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":406,"ADTHAUT":"No","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1092,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.64009,"AVALU":"mg/L","BASE2":9.13023,"BASE":9.44601,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.49014,"PCHG2":-5.36832,"CHG":-0.80592,"PCHG":-8.53185,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-04 21:47:21","ADY":377,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-305","SUBJID":"id-305","SITEID":"CHN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.83617,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-20","TRTSDTM":"2021-01-23 21:47:21","TRTEDTM":"2022-02-18 17:51:42","TRT01SDTM":"2021-01-23 21:47:21","TRT01EDTM":"2021-02-18 11:51:42","TRT02SDTM":"2021-02-18 11:51:42","TRT02EDTM":"2022-02-18 17:51:42","AP01SDTM":"2021-01-23 21:47:21","AP01EDTM":"2021-02-18 11:51:42","AP02SDTM":"2021-02-18 11:51:42","AP02EDTM":"2022-02-18 17:51:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":391,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":406,"ADTHAUT":"No","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2242,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94051,"AVALU":"g/L","BASE2":2.94051,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-12 21:47:21","ADY":48,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-305","SUBJID":"id-305","SITEID":"CHN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.83617,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-20","TRTSDTM":"2021-01-23 21:47:21","TRTEDTM":"2022-02-18 17:51:42","TRT01SDTM":"2021-01-23 21:47:21","TRT01EDTM":"2021-02-18 11:51:42","TRT02SDTM":"2021-02-18 11:51:42","TRT02EDTM":"2022-02-18 17:51:42","AP01SDTM":"2021-01-23 21:47:21","AP01EDTM":"2021-02-18 11:51:42","AP02SDTM":"2021-02-18 11:51:42","AP02EDTM":"2022-02-18 17:51:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":391,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":406,"ADTHAUT":"No","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5743,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75003,"AVALU":"g/L","BASE2":2.94051,"BASE":2.75003,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.19048,"PCHG2":-6.47793,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-27 21:47:21","ADY":155,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-305","SUBJID":"id-305","SITEID":"CHN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.83617,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-20","TRTSDTM":"2021-01-23 21:47:21","TRTEDTM":"2022-02-18 17:51:42","TRT01SDTM":"2021-01-23 21:47:21","TRT01EDTM":"2021-02-18 11:51:42","TRT02SDTM":"2021-02-18 11:51:42","TRT02EDTM":"2022-02-18 17:51:42","AP01SDTM":"2021-01-23 21:47:21","AP01EDTM":"2021-02-18 11:51:42","AP02SDTM":"2021-02-18 11:51:42","AP02EDTM":"2022-02-18 17:51:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":391,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":406,"ADTHAUT":"No","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5445,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92892,"AVALU":"g/L","BASE2":2.94051,"BASE":2.75003,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01159,"PCHG2":-0.39427,"CHG":0.17889,"PCHG":6.50506,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-04 21:47:21","ADY":224,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-305","SUBJID":"id-305","SITEID":"CHN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.83617,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-20","TRTSDTM":"2021-01-23 21:47:21","TRTEDTM":"2022-02-18 17:51:42","TRT01SDTM":"2021-01-23 21:47:21","TRT01EDTM":"2021-02-18 11:51:42","TRT02SDTM":"2021-02-18 11:51:42","TRT02EDTM":"2022-02-18 17:51:42","AP01SDTM":"2021-01-23 21:47:21","AP01EDTM":"2021-02-18 11:51:42","AP02SDTM":"2021-02-18 11:51:42","AP02EDTM":"2022-02-18 17:51:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":391,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":406,"ADTHAUT":"No","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5917,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89292,"AVALU":"g/L","BASE2":2.94051,"BASE":2.75003,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04759,"PCHG2":-1.61843,"CHG":0.14289,"PCHG":5.1961,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-23 21:47:21","ADY":273,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-305","SUBJID":"id-305","SITEID":"CHN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.83617,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-20","TRTSDTM":"2021-01-23 21:47:21","TRTEDTM":"2022-02-18 17:51:42","TRT01SDTM":"2021-01-23 21:47:21","TRT01EDTM":"2021-02-18 11:51:42","TRT02SDTM":"2021-02-18 11:51:42","TRT02EDTM":"2022-02-18 17:51:42","AP01SDTM":"2021-01-23 21:47:21","AP01EDTM":"2021-02-18 11:51:42","AP02SDTM":"2021-02-18 11:51:42","AP02EDTM":"2022-02-18 17:51:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":391,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":406,"ADTHAUT":"No","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2329,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87152,"AVALU":"g/L","BASE2":2.94051,"BASE":2.75003,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06899,"PCHG2":-2.34622,"CHG":0.12149,"PCHG":4.4179,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-09 21:47:21","ADY":320,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-305","SUBJID":"id-305","SITEID":"CHN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.83617,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-20","TRTSDTM":"2021-01-23 21:47:21","TRTEDTM":"2022-02-18 17:51:42","TRT01SDTM":"2021-01-23 21:47:21","TRT01EDTM":"2021-02-18 11:51:42","TRT02SDTM":"2021-02-18 11:51:42","TRT02EDTM":"2022-02-18 17:51:42","AP01SDTM":"2021-01-23 21:47:21","AP01EDTM":"2021-02-18 11:51:42","AP02SDTM":"2021-02-18 11:51:42","AP02EDTM":"2022-02-18 17:51:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":391,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":406,"ADTHAUT":"No","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2351,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05914,"AVALU":"g/L","BASE2":2.94051,"BASE":2.75003,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11863,"PCHG2":4.03418,"CHG":0.30911,"PCHG":11.24025,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-01-08 21:47:21","ADY":350,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-305","SUBJID":"id-305","SITEID":"CHN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.83617,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-20","TRTSDTM":"2021-01-23 21:47:21","TRTEDTM":"2022-02-18 17:51:42","TRT01SDTM":"2021-01-23 21:47:21","TRT01EDTM":"2021-02-18 11:51:42","TRT02SDTM":"2021-02-18 11:51:42","TRT02EDTM":"2022-02-18 17:51:42","AP01SDTM":"2021-01-23 21:47:21","AP01EDTM":"2021-02-18 11:51:42","AP02SDTM":"2021-02-18 11:51:42","AP02EDTM":"2022-02-18 17:51:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":391,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":16,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":406,"ADTHAUT":"No","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4735,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76827,"AVALU":"g/L","BASE2":2.94051,"BASE":2.75003,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17224,"PCHG2":-5.85763,"CHG":0.01824,"PCHG":0.66327,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-04 21:47:21","ADY":377,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-375","SUBJID":"id-375","SITEID":"CHN-14","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.09912,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-27 06:46:31","TRTEDTM":"2023-03-28 00:46:31","TRT01SDTM":"2020-03-27 06:46:31","TRT01EDTM":"2022-03-27 18:46:31","TRT02SDTM":"2022-03-27 18:46:31","TRT02EDTM":"2023-03-28 00:46:31","AP01SDTM":"2020-03-27 06:46:31","AP01EDTM":"2022-03-27 18:46:31","AP02SDTM":"2022-03-27 18:46:31","AP02EDTM":"2023-03-28 00:46:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-28","EOSDY":1096,"LSTALVDT":"2023-04-22","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":386,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.97193,"AVALU":"U/L","BASE2":19.97193,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-18 06:46:31","ADY":22,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-375","SUBJID":"id-375","SITEID":"CHN-14","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.09912,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-27 06:46:31","TRTEDTM":"2023-03-28 00:46:31","TRT01SDTM":"2020-03-27 06:46:31","TRT01EDTM":"2022-03-27 18:46:31","TRT02SDTM":"2022-03-27 18:46:31","TRT02EDTM":"2023-03-28 00:46:31","AP01SDTM":"2020-03-27 06:46:31","AP01EDTM":"2022-03-27 18:46:31","AP02SDTM":"2022-03-27 18:46:31","AP02EDTM":"2023-03-28 00:46:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-28","EOSDY":1096,"LSTALVDT":"2023-04-22","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7383,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.44764,"AVALU":"U/L","BASE2":19.97193,"BASE":12.44764,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-7.5243,"PCHG2":-37.67435,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-05 06:46:31","ADY":649,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-375","SUBJID":"id-375","SITEID":"CHN-14","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.09912,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-27 06:46:31","TRTEDTM":"2023-03-28 00:46:31","TRT01SDTM":"2020-03-27 06:46:31","TRT01EDTM":"2022-03-27 18:46:31","TRT02SDTM":"2022-03-27 18:46:31","TRT02EDTM":"2023-03-28 00:46:31","AP01SDTM":"2020-03-27 06:46:31","AP01EDTM":"2022-03-27 18:46:31","AP02SDTM":"2022-03-27 18:46:31","AP02EDTM":"2023-03-28 00:46:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-28","EOSDY":1096,"LSTALVDT":"2023-04-22","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3860,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.67027,"AVALU":"U/L","BASE2":19.97193,"BASE":12.44764,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.30166,"PCHG2":-36.55962,"CHG":0.22263,"PCHG":1.78856,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-19 06:46:31","ADY":753,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-375","SUBJID":"id-375","SITEID":"CHN-14","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.09912,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-27 06:46:31","TRTEDTM":"2023-03-28 00:46:31","TRT01SDTM":"2020-03-27 06:46:31","TRT01EDTM":"2022-03-27 18:46:31","TRT02SDTM":"2022-03-27 18:46:31","TRT02EDTM":"2023-03-28 00:46:31","AP01SDTM":"2020-03-27 06:46:31","AP01EDTM":"2022-03-27 18:46:31","AP02SDTM":"2022-03-27 18:46:31","AP02EDTM":"2023-03-28 00:46:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-28","EOSDY":1096,"LSTALVDT":"2023-04-22","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":482,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.55303,"AVALU":"U/L","BASE2":19.97193,"BASE":12.44764,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.4189,"PCHG2":-32.1396,"CHG":1.1054,"PCHG":8.88037,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-01 06:46:31","ADY":857,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-375","SUBJID":"id-375","SITEID":"CHN-14","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.09912,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-27 06:46:31","TRTEDTM":"2023-03-28 00:46:31","TRT01SDTM":"2020-03-27 06:46:31","TRT01EDTM":"2022-03-27 18:46:31","TRT02SDTM":"2022-03-27 18:46:31","TRT02EDTM":"2023-03-28 00:46:31","AP01SDTM":"2020-03-27 06:46:31","AP01EDTM":"2022-03-27 18:46:31","AP02SDTM":"2022-03-27 18:46:31","AP02EDTM":"2023-03-28 00:46:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-28","EOSDY":1096,"LSTALVDT":"2023-04-22","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5915,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.39512,"AVALU":"U/L","BASE2":19.97193,"BASE":12.44764,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.57681,"PCHG2":-12.90217,"CHG":4.94748,"PCHG":39.74636,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-12 06:46:31","ADY":868,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-375","SUBJID":"id-375","SITEID":"CHN-14","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.09912,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-27 06:46:31","TRTEDTM":"2023-03-28 00:46:31","TRT01SDTM":"2020-03-27 06:46:31","TRT01EDTM":"2022-03-27 18:46:31","TRT02SDTM":"2022-03-27 18:46:31","TRT02EDTM":"2023-03-28 00:46:31","AP01SDTM":"2020-03-27 06:46:31","AP01EDTM":"2022-03-27 18:46:31","AP02SDTM":"2022-03-27 18:46:31","AP02EDTM":"2023-03-28 00:46:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-28","EOSDY":1096,"LSTALVDT":"2023-04-22","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3329,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.78045,"AVALU":"U/L","BASE2":19.97193,"BASE":12.44764,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.80851,"PCHG2":24.07635,"CHG":12.33281,"PCHG":99.07751,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-07 06:46:31","ADY":924,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-375","SUBJID":"id-375","SITEID":"CHN-14","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.09912,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-27 06:46:31","TRTEDTM":"2023-03-28 00:46:31","TRT01SDTM":"2020-03-27 06:46:31","TRT01EDTM":"2022-03-27 18:46:31","TRT02SDTM":"2022-03-27 18:46:31","TRT02EDTM":"2023-03-28 00:46:31","AP01SDTM":"2020-03-27 06:46:31","AP01EDTM":"2022-03-27 18:46:31","AP02SDTM":"2022-03-27 18:46:31","AP02EDTM":"2023-03-28 00:46:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-28","EOSDY":1096,"LSTALVDT":"2023-04-22","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7489,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.33348,"AVALU":"U/L","BASE2":19.97193,"BASE":12.44764,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.36155,"PCHG2":46.87351,"CHG":16.88584,"PCHG":135.65501,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-10 06:46:31","ADY":958,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-375","SUBJID":"id-375","SITEID":"CHN-14","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.09912,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-27 06:46:31","TRTEDTM":"2023-03-28 00:46:31","TRT01SDTM":"2020-03-27 06:46:31","TRT01EDTM":"2022-03-27 18:46:31","TRT02SDTM":"2022-03-27 18:46:31","TRT02EDTM":"2023-03-28 00:46:31","AP01SDTM":"2020-03-27 06:46:31","AP01EDTM":"2022-03-27 18:46:31","AP02SDTM":"2022-03-27 18:46:31","AP02EDTM":"2023-03-28 00:46:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-28","EOSDY":1096,"LSTALVDT":"2023-04-22","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7631,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.19856,"AVALU":"mg/L","BASE2":9.19856,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-18 06:46:31","ADY":22,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-375","SUBJID":"id-375","SITEID":"CHN-14","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.09912,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-27 06:46:31","TRTEDTM":"2023-03-28 00:46:31","TRT01SDTM":"2020-03-27 06:46:31","TRT01EDTM":"2022-03-27 18:46:31","TRT02SDTM":"2022-03-27 18:46:31","TRT02EDTM":"2023-03-28 00:46:31","AP01SDTM":"2020-03-27 06:46:31","AP01EDTM":"2022-03-27 18:46:31","AP02SDTM":"2022-03-27 18:46:31","AP02EDTM":"2023-03-28 00:46:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-28","EOSDY":1096,"LSTALVDT":"2023-04-22","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6683,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.01595,"AVALU":"mg/L","BASE2":9.19856,"BASE":9.01595,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.18261,"PCHG2":-1.98516,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-05 06:46:31","ADY":649,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-375","SUBJID":"id-375","SITEID":"CHN-14","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.09912,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-27 06:46:31","TRTEDTM":"2023-03-28 00:46:31","TRT01SDTM":"2020-03-27 06:46:31","TRT01EDTM":"2022-03-27 18:46:31","TRT02SDTM":"2022-03-27 18:46:31","TRT02EDTM":"2023-03-28 00:46:31","AP01SDTM":"2020-03-27 06:46:31","AP01EDTM":"2022-03-27 18:46:31","AP02SDTM":"2022-03-27 18:46:31","AP02EDTM":"2023-03-28 00:46:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-28","EOSDY":1096,"LSTALVDT":"2023-04-22","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3106,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.40509,"AVALU":"mg/L","BASE2":9.19856,"BASE":9.01595,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.79347,"PCHG2":-19.49733,"CHG":-1.61087,"PCHG":-17.86686,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2022-04-19 06:46:31","ADY":753,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-375","SUBJID":"id-375","SITEID":"CHN-14","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.09912,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-27 06:46:31","TRTEDTM":"2023-03-28 00:46:31","TRT01SDTM":"2020-03-27 06:46:31","TRT01EDTM":"2022-03-27 18:46:31","TRT02SDTM":"2022-03-27 18:46:31","TRT02EDTM":"2023-03-28 00:46:31","AP01SDTM":"2020-03-27 06:46:31","AP01EDTM":"2022-03-27 18:46:31","AP02SDTM":"2022-03-27 18:46:31","AP02EDTM":"2023-03-28 00:46:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-28","EOSDY":1096,"LSTALVDT":"2023-04-22","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6956,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.83311,"AVALU":"mg/L","BASE2":9.19856,"BASE":9.01595,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.63455,"PCHG2":6.89838,"CHG":0.81716,"PCHG":9.06346,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-01 06:46:31","ADY":857,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-375","SUBJID":"id-375","SITEID":"CHN-14","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.09912,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-27 06:46:31","TRTEDTM":"2023-03-28 00:46:31","TRT01SDTM":"2020-03-27 06:46:31","TRT01EDTM":"2022-03-27 18:46:31","TRT02SDTM":"2022-03-27 18:46:31","TRT02EDTM":"2023-03-28 00:46:31","AP01SDTM":"2020-03-27 06:46:31","AP01EDTM":"2022-03-27 18:46:31","AP02SDTM":"2022-03-27 18:46:31","AP02EDTM":"2023-03-28 00:46:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-28","EOSDY":1096,"LSTALVDT":"2023-04-22","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2907,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.34533,"AVALU":"mg/L","BASE2":9.19856,"BASE":9.01595,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14677,"PCHG2":1.59559,"CHG":0.32938,"PCHG":3.65327,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-12 06:46:31","ADY":868,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-375","SUBJID":"id-375","SITEID":"CHN-14","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.09912,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-27 06:46:31","TRTEDTM":"2023-03-28 00:46:31","TRT01SDTM":"2020-03-27 06:46:31","TRT01EDTM":"2022-03-27 18:46:31","TRT02SDTM":"2022-03-27 18:46:31","TRT02EDTM":"2023-03-28 00:46:31","AP01SDTM":"2020-03-27 06:46:31","AP01EDTM":"2022-03-27 18:46:31","AP02SDTM":"2022-03-27 18:46:31","AP02EDTM":"2023-03-28 00:46:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-28","EOSDY":1096,"LSTALVDT":"2023-04-22","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3188,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.88051,"AVALU":"mg/L","BASE2":9.19856,"BASE":9.01595,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.31805,"PCHG2":-14.32886,"CHG":-1.13544,"PCHG":-12.59371,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-10-07 06:46:31","ADY":924,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-375","SUBJID":"id-375","SITEID":"CHN-14","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.09912,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-27 06:46:31","TRTEDTM":"2023-03-28 00:46:31","TRT01SDTM":"2020-03-27 06:46:31","TRT01EDTM":"2022-03-27 18:46:31","TRT02SDTM":"2022-03-27 18:46:31","TRT02EDTM":"2023-03-28 00:46:31","AP01SDTM":"2020-03-27 06:46:31","AP01EDTM":"2022-03-27 18:46:31","AP02SDTM":"2022-03-27 18:46:31","AP02EDTM":"2023-03-28 00:46:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-28","EOSDY":1096,"LSTALVDT":"2023-04-22","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":153,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.91962,"AVALU":"mg/L","BASE2":9.19856,"BASE":9.01595,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.27894,"PCHG2":-13.90367,"CHG":-1.09633,"PCHG":-12.15991,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-11-10 06:46:31","ADY":958,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-375","SUBJID":"id-375","SITEID":"CHN-14","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.09912,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-27 06:46:31","TRTEDTM":"2023-03-28 00:46:31","TRT01SDTM":"2020-03-27 06:46:31","TRT01EDTM":"2022-03-27 18:46:31","TRT02SDTM":"2022-03-27 18:46:31","TRT02EDTM":"2023-03-28 00:46:31","AP01SDTM":"2020-03-27 06:46:31","AP01EDTM":"2022-03-27 18:46:31","AP02SDTM":"2022-03-27 18:46:31","AP02EDTM":"2023-03-28 00:46:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-28","EOSDY":1096,"LSTALVDT":"2023-04-22","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2136,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97912,"AVALU":"g/L","BASE2":2.97912,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-18 06:46:31","ADY":22,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-375","SUBJID":"id-375","SITEID":"CHN-14","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.09912,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-27 06:46:31","TRTEDTM":"2023-03-28 00:46:31","TRT01SDTM":"2020-03-27 06:46:31","TRT01EDTM":"2022-03-27 18:46:31","TRT02SDTM":"2022-03-27 18:46:31","TRT02EDTM":"2023-03-28 00:46:31","AP01SDTM":"2020-03-27 06:46:31","AP01EDTM":"2022-03-27 18:46:31","AP02SDTM":"2022-03-27 18:46:31","AP02EDTM":"2023-03-28 00:46:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-28","EOSDY":1096,"LSTALVDT":"2023-04-22","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7760,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87833,"AVALU":"g/L","BASE2":2.97912,"BASE":2.87833,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.1008,"PCHG2":-3.38343,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-05 06:46:31","ADY":649,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-375","SUBJID":"id-375","SITEID":"CHN-14","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.09912,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-27 06:46:31","TRTEDTM":"2023-03-28 00:46:31","TRT01SDTM":"2020-03-27 06:46:31","TRT01EDTM":"2022-03-27 18:46:31","TRT02SDTM":"2022-03-27 18:46:31","TRT02EDTM":"2023-03-28 00:46:31","AP01SDTM":"2020-03-27 06:46:31","AP01EDTM":"2022-03-27 18:46:31","AP02SDTM":"2022-03-27 18:46:31","AP02EDTM":"2023-03-28 00:46:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-28","EOSDY":1096,"LSTALVDT":"2023-04-22","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1849,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77944,"AVALU":"g/L","BASE2":2.97912,"BASE":2.87833,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19969,"PCHG2":-6.70294,"CHG":-0.09889,"PCHG":-3.43576,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-19 06:46:31","ADY":753,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-375","SUBJID":"id-375","SITEID":"CHN-14","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.09912,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-27 06:46:31","TRTEDTM":"2023-03-28 00:46:31","TRT01SDTM":"2020-03-27 06:46:31","TRT01EDTM":"2022-03-27 18:46:31","TRT02SDTM":"2022-03-27 18:46:31","TRT02EDTM":"2023-03-28 00:46:31","AP01SDTM":"2020-03-27 06:46:31","AP01EDTM":"2022-03-27 18:46:31","AP02SDTM":"2022-03-27 18:46:31","AP02EDTM":"2023-03-28 00:46:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-28","EOSDY":1096,"LSTALVDT":"2023-04-22","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3706,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.14802,"AVALU":"g/L","BASE2":2.97912,"BASE":2.87833,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1689,"PCHG2":5.66938,"CHG":0.26969,"PCHG":9.36983,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-08-01 06:46:31","ADY":857,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-375","SUBJID":"id-375","SITEID":"CHN-14","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.09912,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-27 06:46:31","TRTEDTM":"2023-03-28 00:46:31","TRT01SDTM":"2020-03-27 06:46:31","TRT01EDTM":"2022-03-27 18:46:31","TRT02SDTM":"2022-03-27 18:46:31","TRT02EDTM":"2023-03-28 00:46:31","AP01SDTM":"2020-03-27 06:46:31","AP01EDTM":"2022-03-27 18:46:31","AP02SDTM":"2022-03-27 18:46:31","AP02EDTM":"2023-03-28 00:46:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-28","EOSDY":1096,"LSTALVDT":"2023-04-22","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6604,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95042,"AVALU":"g/L","BASE2":2.97912,"BASE":2.87833,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0287,"PCHG2":-0.9635,"CHG":0.07209,"PCHG":2.50468,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-12 06:46:31","ADY":868,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-375","SUBJID":"id-375","SITEID":"CHN-14","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.09912,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-27 06:46:31","TRTEDTM":"2023-03-28 00:46:31","TRT01SDTM":"2020-03-27 06:46:31","TRT01EDTM":"2022-03-27 18:46:31","TRT02SDTM":"2022-03-27 18:46:31","TRT02EDTM":"2023-03-28 00:46:31","AP01SDTM":"2020-03-27 06:46:31","AP01EDTM":"2022-03-27 18:46:31","AP02SDTM":"2022-03-27 18:46:31","AP02EDTM":"2023-03-28 00:46:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-28","EOSDY":1096,"LSTALVDT":"2023-04-22","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7643,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87088,"AVALU":"g/L","BASE2":2.97912,"BASE":2.87833,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10825,"PCHG2":-3.63353,"CHG":-0.00745,"PCHG":-0.25886,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-07 06:46:31","ADY":924,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-375","SUBJID":"id-375","SITEID":"CHN-14","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.09912,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-27 06:46:31","TRTEDTM":"2023-03-28 00:46:31","TRT01SDTM":"2020-03-27 06:46:31","TRT01EDTM":"2022-03-27 18:46:31","TRT02SDTM":"2022-03-27 18:46:31","TRT02EDTM":"2023-03-28 00:46:31","AP01SDTM":"2020-03-27 06:46:31","AP01EDTM":"2022-03-27 18:46:31","AP02SDTM":"2022-03-27 18:46:31","AP02EDTM":"2023-03-28 00:46:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-28","EOSDY":1096,"LSTALVDT":"2023-04-22","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3742,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92347,"AVALU":"g/L","BASE2":2.97912,"BASE":2.87833,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05566,"PCHG2":-1.86821,"CHG":0.04514,"PCHG":1.56828,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-10 06:46:31","ADY":958,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-56","SUBJID":"id-56","SITEID":"CHN-14","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.51563,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-07","TRTSDTM":"2019-10-10 18:04:36","TRTEDTM":"2022-02-13 22:24:30","TRT01SDTM":"2019-10-10 18:04:36","TRT01EDTM":"2021-02-13 16:24:30","TRT02SDTM":"2021-02-13 16:24:30","TRT02EDTM":"2022-02-13 22:24:30","AP01SDTM":"2019-10-10 18:04:36","AP01EDTM":"2021-02-13 16:24:30","AP02SDTM":"2021-02-13 16:24:30","AP02EDTM":"2022-02-13 22:24:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":858,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-03","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2728,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.20887,"AVALU":"U/L","BASE2":15.20887,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-10 18:04:36","ADY":0,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-56","SUBJID":"id-56","SITEID":"CHN-14","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.51563,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-07","TRTSDTM":"2019-10-10 18:04:36","TRTEDTM":"2022-02-13 22:24:30","TRT01SDTM":"2019-10-10 18:04:36","TRT01EDTM":"2021-02-13 16:24:30","TRT02SDTM":"2021-02-13 16:24:30","TRT02EDTM":"2022-02-13 22:24:30","AP01SDTM":"2019-10-10 18:04:36","AP01EDTM":"2021-02-13 16:24:30","AP02SDTM":"2021-02-13 16:24:30","AP02EDTM":"2022-02-13 22:24:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":858,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-03","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5762,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.56479,"AVALU":"U/L","BASE2":15.20887,"BASE":29.56479,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":14.35592,"PCHG2":94.39177,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-19 18:04:36","ADY":40,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-56","SUBJID":"id-56","SITEID":"CHN-14","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.51563,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-07","TRTSDTM":"2019-10-10 18:04:36","TRTEDTM":"2022-02-13 22:24:30","TRT01SDTM":"2019-10-10 18:04:36","TRT01EDTM":"2021-02-13 16:24:30","TRT02SDTM":"2021-02-13 16:24:30","TRT02EDTM":"2022-02-13 22:24:30","AP01SDTM":"2019-10-10 18:04:36","AP01EDTM":"2021-02-13 16:24:30","AP02SDTM":"2021-02-13 16:24:30","AP02EDTM":"2022-02-13 22:24:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":858,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-03","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1509,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.93399,"AVALU":"U/L","BASE2":15.20887,"BASE":29.56479,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.72512,"PCHG2":37.64331,"CHG":-8.6308,"PCHG":-29.19283,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-23 18:04:36","ADY":44,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-56","SUBJID":"id-56","SITEID":"CHN-14","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.51563,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-07","TRTSDTM":"2019-10-10 18:04:36","TRTEDTM":"2022-02-13 22:24:30","TRT01SDTM":"2019-10-10 18:04:36","TRT01EDTM":"2021-02-13 16:24:30","TRT02SDTM":"2021-02-13 16:24:30","TRT02EDTM":"2022-02-13 22:24:30","AP01SDTM":"2019-10-10 18:04:36","AP01EDTM":"2021-02-13 16:24:30","AP02SDTM":"2021-02-13 16:24:30","AP02EDTM":"2022-02-13 22:24:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":858,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-03","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3599,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.71809,"AVALU":"U/L","BASE2":15.20887,"BASE":29.56479,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.50923,"PCHG2":36.22379,"CHG":-8.84669,"PCHG":-29.92307,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-02 18:04:36","ADY":266,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-56","SUBJID":"id-56","SITEID":"CHN-14","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.51563,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-07","TRTSDTM":"2019-10-10 18:04:36","TRTEDTM":"2022-02-13 22:24:30","TRT01SDTM":"2019-10-10 18:04:36","TRT01EDTM":"2021-02-13 16:24:30","TRT02SDTM":"2021-02-13 16:24:30","TRT02EDTM":"2022-02-13 22:24:30","AP01SDTM":"2019-10-10 18:04:36","AP01EDTM":"2021-02-13 16:24:30","AP02SDTM":"2021-02-13 16:24:30","AP02EDTM":"2022-02-13 22:24:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":858,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-03","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7394,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.94234,"AVALU":"U/L","BASE2":15.20887,"BASE":29.56479,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.26653,"PCHG2":-21.4778,"CHG":-17.62245,"PCHG":-59.60621,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-27 18:04:36","ADY":322,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-56","SUBJID":"id-56","SITEID":"CHN-14","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.51563,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-07","TRTSDTM":"2019-10-10 18:04:36","TRTEDTM":"2022-02-13 22:24:30","TRT01SDTM":"2019-10-10 18:04:36","TRT01EDTM":"2021-02-13 16:24:30","TRT02SDTM":"2021-02-13 16:24:30","TRT02EDTM":"2022-02-13 22:24:30","AP01SDTM":"2019-10-10 18:04:36","AP01EDTM":"2021-02-13 16:24:30","AP02SDTM":"2021-02-13 16:24:30","AP02EDTM":"2022-02-13 22:24:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":858,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-03","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1228,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.81601,"AVALU":"U/L","BASE2":15.20887,"BASE":29.56479,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.39286,"PCHG2":-61.75912,"CHG":-23.74878,"PCHG":-80.32793,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-09-15 18:04:36","ADY":341,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-56","SUBJID":"id-56","SITEID":"CHN-14","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.51563,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-07","TRTSDTM":"2019-10-10 18:04:36","TRTEDTM":"2022-02-13 22:24:30","TRT01SDTM":"2019-10-10 18:04:36","TRT01EDTM":"2021-02-13 16:24:30","TRT02SDTM":"2021-02-13 16:24:30","TRT02EDTM":"2022-02-13 22:24:30","AP01SDTM":"2019-10-10 18:04:36","AP01EDTM":"2021-02-13 16:24:30","AP02SDTM":"2021-02-13 16:24:30","AP02EDTM":"2022-02-13 22:24:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":858,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-03","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3669,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.58717,"AVALU":"U/L","BASE2":15.20887,"BASE":29.56479,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.62169,"PCHG2":-17.23793,"CHG":-16.97761,"PCHG":-57.42512,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-06 18:04:36","ADY":666,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-56","SUBJID":"id-56","SITEID":"CHN-14","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.51563,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-07","TRTSDTM":"2019-10-10 18:04:36","TRTEDTM":"2022-02-13 22:24:30","TRT01SDTM":"2019-10-10 18:04:36","TRT01EDTM":"2021-02-13 16:24:30","TRT02SDTM":"2021-02-13 16:24:30","TRT02EDTM":"2022-02-13 22:24:30","AP01SDTM":"2019-10-10 18:04:36","AP01EDTM":"2021-02-13 16:24:30","AP02SDTM":"2021-02-13 16:24:30","AP02EDTM":"2022-02-13 22:24:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":858,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-03","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4239,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.33405,"AVALU":"mg/L","BASE2":9.33405,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-10 18:04:36","ADY":0,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-56","SUBJID":"id-56","SITEID":"CHN-14","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.51563,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-07","TRTSDTM":"2019-10-10 18:04:36","TRTEDTM":"2022-02-13 22:24:30","TRT01SDTM":"2019-10-10 18:04:36","TRT01EDTM":"2021-02-13 16:24:30","TRT02SDTM":"2021-02-13 16:24:30","TRT02EDTM":"2022-02-13 22:24:30","AP01SDTM":"2019-10-10 18:04:36","AP01EDTM":"2021-02-13 16:24:30","AP02SDTM":"2021-02-13 16:24:30","AP02EDTM":"2022-02-13 22:24:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":858,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-03","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4231,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.37667,"AVALU":"mg/L","BASE2":9.33405,"BASE":9.37667,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.04262,"PCHG2":0.4566,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-19 18:04:36","ADY":40,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-56","SUBJID":"id-56","SITEID":"CHN-14","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.51563,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-07","TRTSDTM":"2019-10-10 18:04:36","TRTEDTM":"2022-02-13 22:24:30","TRT01SDTM":"2019-10-10 18:04:36","TRT01EDTM":"2021-02-13 16:24:30","TRT02SDTM":"2021-02-13 16:24:30","TRT02EDTM":"2022-02-13 22:24:30","AP01SDTM":"2019-10-10 18:04:36","AP01EDTM":"2021-02-13 16:24:30","AP02SDTM":"2021-02-13 16:24:30","AP02EDTM":"2022-02-13 22:24:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":858,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-03","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5096,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.12953,"AVALU":"mg/L","BASE2":9.33405,"BASE":9.37667,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20452,"PCHG2":-2.19113,"CHG":-0.24714,"PCHG":-2.6357,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-23 18:04:36","ADY":44,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-56","SUBJID":"id-56","SITEID":"CHN-14","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.51563,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-07","TRTSDTM":"2019-10-10 18:04:36","TRTEDTM":"2022-02-13 22:24:30","TRT01SDTM":"2019-10-10 18:04:36","TRT01EDTM":"2021-02-13 16:24:30","TRT02SDTM":"2021-02-13 16:24:30","TRT02EDTM":"2022-02-13 22:24:30","AP01SDTM":"2019-10-10 18:04:36","AP01EDTM":"2021-02-13 16:24:30","AP02SDTM":"2021-02-13 16:24:30","AP02EDTM":"2022-02-13 22:24:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":858,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-03","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":242,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.98528,"AVALU":"mg/L","BASE2":9.33405,"BASE":9.37667,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.65123,"PCHG2":6.97693,"CHG":0.60861,"PCHG":6.4907,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-02 18:04:36","ADY":266,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-56","SUBJID":"id-56","SITEID":"CHN-14","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.51563,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-07","TRTSDTM":"2019-10-10 18:04:36","TRTEDTM":"2022-02-13 22:24:30","TRT01SDTM":"2019-10-10 18:04:36","TRT01EDTM":"2021-02-13 16:24:30","TRT02SDTM":"2021-02-13 16:24:30","TRT02EDTM":"2022-02-13 22:24:30","AP01SDTM":"2019-10-10 18:04:36","AP01EDTM":"2021-02-13 16:24:30","AP02SDTM":"2021-02-13 16:24:30","AP02EDTM":"2022-02-13 22:24:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":858,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-03","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6204,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.47619,"AVALU":"mg/L","BASE2":9.33405,"BASE":9.37667,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.85786,"PCHG2":-19.9041,"CHG":-1.90048,"PCHG":-20.26816,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-08-27 18:04:36","ADY":322,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-56","SUBJID":"id-56","SITEID":"CHN-14","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.51563,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-07","TRTSDTM":"2019-10-10 18:04:36","TRTEDTM":"2022-02-13 22:24:30","TRT01SDTM":"2019-10-10 18:04:36","TRT01EDTM":"2021-02-13 16:24:30","TRT02SDTM":"2021-02-13 16:24:30","TRT02EDTM":"2022-02-13 22:24:30","AP01SDTM":"2019-10-10 18:04:36","AP01EDTM":"2021-02-13 16:24:30","AP02SDTM":"2021-02-13 16:24:30","AP02EDTM":"2022-02-13 22:24:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":858,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-03","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6543,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.531,"AVALU":"mg/L","BASE2":9.33405,"BASE":9.37667,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.80305,"PCHG2":-8.60345,"CHG":-0.84567,"PCHG":-9.01887,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-15 18:04:36","ADY":341,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-56","SUBJID":"id-56","SITEID":"CHN-14","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.51563,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-07","TRTSDTM":"2019-10-10 18:04:36","TRTEDTM":"2022-02-13 22:24:30","TRT01SDTM":"2019-10-10 18:04:36","TRT01EDTM":"2021-02-13 16:24:30","TRT02SDTM":"2021-02-13 16:24:30","TRT02EDTM":"2022-02-13 22:24:30","AP01SDTM":"2019-10-10 18:04:36","AP01EDTM":"2021-02-13 16:24:30","AP02SDTM":"2021-02-13 16:24:30","AP02EDTM":"2022-02-13 22:24:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":858,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-03","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1603,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.83831,"AVALU":"mg/L","BASE2":9.33405,"BASE":9.37667,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.49575,"PCHG2":-16.0246,"CHG":-1.53836,"PCHG":-16.40629,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-08-06 18:04:36","ADY":666,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-56","SUBJID":"id-56","SITEID":"CHN-14","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.51563,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-07","TRTSDTM":"2019-10-10 18:04:36","TRTEDTM":"2022-02-13 22:24:30","TRT01SDTM":"2019-10-10 18:04:36","TRT01EDTM":"2021-02-13 16:24:30","TRT02SDTM":"2021-02-13 16:24:30","TRT02EDTM":"2022-02-13 22:24:30","AP01SDTM":"2019-10-10 18:04:36","AP01EDTM":"2021-02-13 16:24:30","AP02SDTM":"2021-02-13 16:24:30","AP02EDTM":"2022-02-13 22:24:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":858,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-03","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2146,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92216,"AVALU":"g/L","BASE2":2.92216,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-10 18:04:36","ADY":0,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-56","SUBJID":"id-56","SITEID":"CHN-14","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.51563,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-07","TRTSDTM":"2019-10-10 18:04:36","TRTEDTM":"2022-02-13 22:24:30","TRT01SDTM":"2019-10-10 18:04:36","TRT01EDTM":"2021-02-13 16:24:30","TRT02SDTM":"2021-02-13 16:24:30","TRT02EDTM":"2022-02-13 22:24:30","AP01SDTM":"2019-10-10 18:04:36","AP01EDTM":"2021-02-13 16:24:30","AP02SDTM":"2021-02-13 16:24:30","AP02EDTM":"2022-02-13 22:24:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":858,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-03","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":981,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8831,"AVALU":"g/L","BASE2":2.92216,"BASE":2.8831,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.03906,"PCHG2":-1.33676,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-19 18:04:36","ADY":40,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-56","SUBJID":"id-56","SITEID":"CHN-14","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.51563,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-07","TRTSDTM":"2019-10-10 18:04:36","TRTEDTM":"2022-02-13 22:24:30","TRT01SDTM":"2019-10-10 18:04:36","TRT01EDTM":"2021-02-13 16:24:30","TRT02SDTM":"2021-02-13 16:24:30","TRT02EDTM":"2022-02-13 22:24:30","AP01SDTM":"2019-10-10 18:04:36","AP01EDTM":"2021-02-13 16:24:30","AP02SDTM":"2021-02-13 16:24:30","AP02EDTM":"2022-02-13 22:24:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":858,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-03","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6248,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89865,"AVALU":"g/L","BASE2":2.92216,"BASE":2.8831,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02351,"PCHG2":-0.80467,"CHG":0.01555,"PCHG":0.5393,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-23 18:04:36","ADY":44,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-56","SUBJID":"id-56","SITEID":"CHN-14","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.51563,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-07","TRTSDTM":"2019-10-10 18:04:36","TRTEDTM":"2022-02-13 22:24:30","TRT01SDTM":"2019-10-10 18:04:36","TRT01EDTM":"2021-02-13 16:24:30","TRT02SDTM":"2021-02-13 16:24:30","TRT02EDTM":"2022-02-13 22:24:30","AP01SDTM":"2019-10-10 18:04:36","AP01EDTM":"2021-02-13 16:24:30","AP02SDTM":"2021-02-13 16:24:30","AP02EDTM":"2022-02-13 22:24:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":858,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-03","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4084,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93193,"AVALU":"g/L","BASE2":2.92216,"BASE":2.8831,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00977,"PCHG2":0.33421,"CHG":0.04883,"PCHG":1.6936,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-02 18:04:36","ADY":266,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-56","SUBJID":"id-56","SITEID":"CHN-14","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.51563,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-07","TRTSDTM":"2019-10-10 18:04:36","TRTEDTM":"2022-02-13 22:24:30","TRT01SDTM":"2019-10-10 18:04:36","TRT01EDTM":"2021-02-13 16:24:30","TRT02SDTM":"2021-02-13 16:24:30","TRT02EDTM":"2022-02-13 22:24:30","AP01SDTM":"2019-10-10 18:04:36","AP01EDTM":"2021-02-13 16:24:30","AP02SDTM":"2021-02-13 16:24:30","AP02EDTM":"2022-02-13 22:24:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":858,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-03","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":244,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.6888,"AVALU":"g/L","BASE2":2.92216,"BASE":2.8831,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.23336,"PCHG2":-7.98593,"CHG":-0.1943,"PCHG":-6.73926,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-27 18:04:36","ADY":322,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-56","SUBJID":"id-56","SITEID":"CHN-14","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.51563,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-07","TRTSDTM":"2019-10-10 18:04:36","TRTEDTM":"2022-02-13 22:24:30","TRT01SDTM":"2019-10-10 18:04:36","TRT01EDTM":"2021-02-13 16:24:30","TRT02SDTM":"2021-02-13 16:24:30","TRT02EDTM":"2022-02-13 22:24:30","AP01SDTM":"2019-10-10 18:04:36","AP01EDTM":"2021-02-13 16:24:30","AP02SDTM":"2021-02-13 16:24:30","AP02EDTM":"2022-02-13 22:24:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":858,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-03","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":278,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92286,"AVALU":"g/L","BASE2":2.92216,"BASE":2.8831,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0007,"PCHG2":0.02403,"CHG":0.03976,"PCHG":1.37922,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-15 18:04:36","ADY":341,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-14-id-56","SUBJID":"id-56","SITEID":"CHN-14","AGE":25,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-14","INVNAM":"Dr. CHN-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.51563,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-07","TRTSDTM":"2019-10-10 18:04:36","TRTEDTM":"2022-02-13 22:24:30","TRT01SDTM":"2019-10-10 18:04:36","TRT01EDTM":"2021-02-13 16:24:30","TRT02SDTM":"2021-02-13 16:24:30","TRT02EDTM":"2022-02-13 22:24:30","AP01SDTM":"2019-10-10 18:04:36","AP01EDTM":"2021-02-13 16:24:30","AP02SDTM":"2021-02-13 16:24:30","AP02EDTM":"2022-02-13 22:24:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":858,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-03","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3587,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83111,"AVALU":"g/L","BASE2":2.92216,"BASE":2.8831,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09105,"PCHG2":-3.11579,"CHG":-0.05199,"PCHG":-1.80314,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-06 18:04:36","ADY":666,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-14","SUBJID":"id-14","SITEID":"CHN-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.02692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-29","TRTSDTM":"2019-09-29 11:34:20","TRTEDTM":"2022-02-15 13:58:07","TRT01SDTM":"2019-09-29 11:34:20","TRT01EDTM":"2021-02-15 07:58:07","TRT02SDTM":"2021-02-15 07:58:07","TRT02EDTM":"2022-02-15 13:58:07","AP01SDTM":"2019-09-29 11:34:20","AP01EDTM":"2021-02-15 07:58:07","AP02SDTM":"2021-02-15 07:58:07","AP02EDTM":"2022-02-15 13:58:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":919,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1248,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.82176,"AVALU":"U/L","BASE2":34.82176,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-05 11:34:20","ADY":37,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-14","SUBJID":"id-14","SITEID":"CHN-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.02692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-29","TRTSDTM":"2019-09-29 11:34:20","TRTEDTM":"2022-02-15 13:58:07","TRT01SDTM":"2019-09-29 11:34:20","TRT01EDTM":"2021-02-15 07:58:07","TRT02SDTM":"2021-02-15 07:58:07","TRT02EDTM":"2022-02-15 13:58:07","AP01SDTM":"2019-09-29 11:34:20","AP01EDTM":"2021-02-15 07:58:07","AP02SDTM":"2021-02-15 07:58:07","AP02EDTM":"2022-02-15 13:58:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":919,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4008,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.90461,"AVALU":"U/L","BASE2":34.82176,"BASE":23.90461,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-10.91715,"PCHG2":-31.35151,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-02 11:34:20","ADY":186,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-14","SUBJID":"id-14","SITEID":"CHN-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.02692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-29","TRTSDTM":"2019-09-29 11:34:20","TRTEDTM":"2022-02-15 13:58:07","TRT01SDTM":"2019-09-29 11:34:20","TRT01EDTM":"2021-02-15 07:58:07","TRT02SDTM":"2021-02-15 07:58:07","TRT02EDTM":"2022-02-15 13:58:07","AP01SDTM":"2019-09-29 11:34:20","AP01EDTM":"2021-02-15 07:58:07","AP02SDTM":"2021-02-15 07:58:07","AP02EDTM":"2022-02-15 13:58:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":919,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7001,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.48884,"AVALU":"U/L","BASE2":34.82176,"BASE":23.90461,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-31.33293,"PCHG2":-89.98088,"CHG":-20.41578,"PCHG":-85.40518,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-06-20 11:34:20","ADY":265,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-14","SUBJID":"id-14","SITEID":"CHN-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.02692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-29","TRTSDTM":"2019-09-29 11:34:20","TRTEDTM":"2022-02-15 13:58:07","TRT01SDTM":"2019-09-29 11:34:20","TRT01EDTM":"2021-02-15 07:58:07","TRT02SDTM":"2021-02-15 07:58:07","TRT02EDTM":"2022-02-15 13:58:07","AP01SDTM":"2019-09-29 11:34:20","AP01EDTM":"2021-02-15 07:58:07","AP02SDTM":"2021-02-15 07:58:07","AP02EDTM":"2022-02-15 13:58:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":919,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7138,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.86836,"AVALU":"U/L","BASE2":34.82176,"BASE":23.90461,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-29.9534,"PCHG2":-86.01919,"CHG":-19.03625,"PCHG":-79.6342,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-06-27 11:34:20","ADY":272,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-14","SUBJID":"id-14","SITEID":"CHN-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.02692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-29","TRTSDTM":"2019-09-29 11:34:20","TRTEDTM":"2022-02-15 13:58:07","TRT01SDTM":"2019-09-29 11:34:20","TRT01EDTM":"2021-02-15 07:58:07","TRT02SDTM":"2021-02-15 07:58:07","TRT02EDTM":"2022-02-15 13:58:07","AP01SDTM":"2019-09-29 11:34:20","AP01EDTM":"2021-02-15 07:58:07","AP02SDTM":"2021-02-15 07:58:07","AP02EDTM":"2022-02-15 13:58:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":919,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1153,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.84823,"AVALU":"U/L","BASE2":34.82176,"BASE":23.90461,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.97353,"PCHG2":-20.02636,"CHG":3.94362,"PCHG":16.4973,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-03 11:34:20","ADY":431,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-14","SUBJID":"id-14","SITEID":"CHN-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.02692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-29","TRTSDTM":"2019-09-29 11:34:20","TRTEDTM":"2022-02-15 13:58:07","TRT01SDTM":"2019-09-29 11:34:20","TRT01EDTM":"2021-02-15 07:58:07","TRT02SDTM":"2021-02-15 07:58:07","TRT02EDTM":"2022-02-15 13:58:07","AP01SDTM":"2019-09-29 11:34:20","AP01EDTM":"2021-02-15 07:58:07","AP02SDTM":"2021-02-15 07:58:07","AP02EDTM":"2022-02-15 13:58:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":919,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2868,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.30727,"AVALU":"U/L","BASE2":34.82176,"BASE":23.90461,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-27.51449,"PCHG2":-79.01522,"CHG":-16.59735,"PCHG":-69.43156,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-30 11:34:20","ADY":548,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-14","SUBJID":"id-14","SITEID":"CHN-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.02692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-29","TRTSDTM":"2019-09-29 11:34:20","TRTEDTM":"2022-02-15 13:58:07","TRT01SDTM":"2019-09-29 11:34:20","TRT01EDTM":"2021-02-15 07:58:07","TRT02SDTM":"2021-02-15 07:58:07","TRT02EDTM":"2022-02-15 13:58:07","AP01SDTM":"2019-09-29 11:34:20","AP01EDTM":"2021-02-15 07:58:07","AP02SDTM":"2021-02-15 07:58:07","AP02EDTM":"2022-02-15 13:58:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":919,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5385,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.84082,"AVALU":"U/L","BASE2":34.82176,"BASE":23.90461,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.98094,"PCHG2":-37.27824,"CHG":-2.06379,"PCHG":-8.63345,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-20 11:34:20","ADY":630,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-14","SUBJID":"id-14","SITEID":"CHN-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.02692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-29","TRTSDTM":"2019-09-29 11:34:20","TRTEDTM":"2022-02-15 13:58:07","TRT01SDTM":"2019-09-29 11:34:20","TRT01EDTM":"2021-02-15 07:58:07","TRT02SDTM":"2021-02-15 07:58:07","TRT02EDTM":"2022-02-15 13:58:07","AP01SDTM":"2019-09-29 11:34:20","AP01EDTM":"2021-02-15 07:58:07","AP02SDTM":"2021-02-15 07:58:07","AP02EDTM":"2022-02-15 13:58:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":919,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6037,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.17966,"AVALU":"mg/L","BASE2":10.17966,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2019-11-05 11:34:20","ADY":37,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-14","SUBJID":"id-14","SITEID":"CHN-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.02692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-29","TRTSDTM":"2019-09-29 11:34:20","TRTEDTM":"2022-02-15 13:58:07","TRT01SDTM":"2019-09-29 11:34:20","TRT01EDTM":"2021-02-15 07:58:07","TRT02SDTM":"2021-02-15 07:58:07","TRT02EDTM":"2022-02-15 13:58:07","AP01SDTM":"2019-09-29 11:34:20","AP01EDTM":"2021-02-15 07:58:07","AP02SDTM":"2021-02-15 07:58:07","AP02EDTM":"2022-02-15 13:58:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":919,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7077,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.26153,"AVALU":"mg/L","BASE2":10.17966,"BASE":9.26153,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.91813,"PCHG2":-9.01926,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-02 11:34:20","ADY":186,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-14","SUBJID":"id-14","SITEID":"CHN-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.02692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-29","TRTSDTM":"2019-09-29 11:34:20","TRTEDTM":"2022-02-15 13:58:07","TRT01SDTM":"2019-09-29 11:34:20","TRT01EDTM":"2021-02-15 07:58:07","TRT02SDTM":"2021-02-15 07:58:07","TRT02EDTM":"2022-02-15 13:58:07","AP01SDTM":"2019-09-29 11:34:20","AP01EDTM":"2021-02-15 07:58:07","AP02SDTM":"2021-02-15 07:58:07","AP02EDTM":"2022-02-15 13:58:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":919,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5994,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.62791,"AVALU":"mg/L","BASE2":10.17966,"BASE":9.26153,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.55175,"PCHG2":-15.24362,"CHG":-0.63362,"PCHG":-6.84141,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-20 11:34:20","ADY":265,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-14","SUBJID":"id-14","SITEID":"CHN-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.02692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-29","TRTSDTM":"2019-09-29 11:34:20","TRTEDTM":"2022-02-15 13:58:07","TRT01SDTM":"2019-09-29 11:34:20","TRT01EDTM":"2021-02-15 07:58:07","TRT02SDTM":"2021-02-15 07:58:07","TRT02EDTM":"2022-02-15 13:58:07","AP01SDTM":"2019-09-29 11:34:20","AP01EDTM":"2021-02-15 07:58:07","AP02SDTM":"2021-02-15 07:58:07","AP02EDTM":"2022-02-15 13:58:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":919,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1890,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.01103,"AVALU":"mg/L","BASE2":10.17966,"BASE":9.26153,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.16863,"PCHG2":-11.48002,"CHG":-0.2505,"PCHG":-2.70471,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-27 11:34:20","ADY":272,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-14","SUBJID":"id-14","SITEID":"CHN-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.02692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-29","TRTSDTM":"2019-09-29 11:34:20","TRTEDTM":"2022-02-15 13:58:07","TRT01SDTM":"2019-09-29 11:34:20","TRT01EDTM":"2021-02-15 07:58:07","TRT02SDTM":"2021-02-15 07:58:07","TRT02EDTM":"2022-02-15 13:58:07","AP01SDTM":"2019-09-29 11:34:20","AP01EDTM":"2021-02-15 07:58:07","AP02SDTM":"2021-02-15 07:58:07","AP02EDTM":"2022-02-15 13:58:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":919,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5785,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.55942,"AVALU":"mg/L","BASE2":10.17966,"BASE":9.26153,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.62025,"PCHG2":-15.91651,"CHG":-0.70212,"PCHG":-7.581,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-03 11:34:20","ADY":431,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-14","SUBJID":"id-14","SITEID":"CHN-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.02692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-29","TRTSDTM":"2019-09-29 11:34:20","TRTEDTM":"2022-02-15 13:58:07","TRT01SDTM":"2019-09-29 11:34:20","TRT01EDTM":"2021-02-15 07:58:07","TRT02SDTM":"2021-02-15 07:58:07","TRT02EDTM":"2022-02-15 13:58:07","AP01SDTM":"2019-09-29 11:34:20","AP01EDTM":"2021-02-15 07:58:07","AP02SDTM":"2021-02-15 07:58:07","AP02EDTM":"2022-02-15 13:58:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":919,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2150,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.91234,"AVALU":"mg/L","BASE2":10.17966,"BASE":9.26153,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.26732,"PCHG2":-32.09657,"CHG":-2.34919,"PCHG":-25.36506,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-03-30 11:34:20","ADY":548,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-14","SUBJID":"id-14","SITEID":"CHN-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.02692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-29","TRTSDTM":"2019-09-29 11:34:20","TRTEDTM":"2022-02-15 13:58:07","TRT01SDTM":"2019-09-29 11:34:20","TRT01EDTM":"2021-02-15 07:58:07","TRT02SDTM":"2021-02-15 07:58:07","TRT02EDTM":"2022-02-15 13:58:07","AP01SDTM":"2019-09-29 11:34:20","AP01EDTM":"2021-02-15 07:58:07","AP02SDTM":"2021-02-15 07:58:07","AP02EDTM":"2022-02-15 13:58:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":919,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2870,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.49863,"AVALU":"mg/L","BASE2":10.17966,"BASE":9.26153,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.68103,"PCHG2":-16.51359,"CHG":-0.7629,"PCHG":-8.23728,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-20 11:34:20","ADY":630,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-14","SUBJID":"id-14","SITEID":"CHN-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.02692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-29","TRTSDTM":"2019-09-29 11:34:20","TRTEDTM":"2022-02-15 13:58:07","TRT01SDTM":"2019-09-29 11:34:20","TRT01EDTM":"2021-02-15 07:58:07","TRT02SDTM":"2021-02-15 07:58:07","TRT02EDTM":"2022-02-15 13:58:07","AP01SDTM":"2019-09-29 11:34:20","AP01EDTM":"2021-02-15 07:58:07","AP02SDTM":"2021-02-15 07:58:07","AP02EDTM":"2022-02-15 13:58:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":919,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6794,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78763,"AVALU":"g/L","BASE2":2.78763,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-05 11:34:20","ADY":37,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-14","SUBJID":"id-14","SITEID":"CHN-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.02692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-29","TRTSDTM":"2019-09-29 11:34:20","TRTEDTM":"2022-02-15 13:58:07","TRT01SDTM":"2019-09-29 11:34:20","TRT01EDTM":"2021-02-15 07:58:07","TRT02SDTM":"2021-02-15 07:58:07","TRT02EDTM":"2022-02-15 13:58:07","AP01SDTM":"2019-09-29 11:34:20","AP01EDTM":"2021-02-15 07:58:07","AP02SDTM":"2021-02-15 07:58:07","AP02EDTM":"2022-02-15 13:58:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":919,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":592,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91513,"AVALU":"g/L","BASE2":2.78763,"BASE":2.91513,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.1275,"PCHG2":4.57393,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-02 11:34:20","ADY":186,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-14","SUBJID":"id-14","SITEID":"CHN-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.02692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-29","TRTSDTM":"2019-09-29 11:34:20","TRTEDTM":"2022-02-15 13:58:07","TRT01SDTM":"2019-09-29 11:34:20","TRT01EDTM":"2021-02-15 07:58:07","TRT02SDTM":"2021-02-15 07:58:07","TRT02EDTM":"2022-02-15 13:58:07","AP01SDTM":"2019-09-29 11:34:20","AP01EDTM":"2021-02-15 07:58:07","AP02SDTM":"2021-02-15 07:58:07","AP02EDTM":"2022-02-15 13:58:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":919,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2612,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80476,"AVALU":"g/L","BASE2":2.78763,"BASE":2.91513,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01713,"PCHG2":0.61436,"CHG":-0.11038,"PCHG":-3.78639,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-20 11:34:20","ADY":265,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-14","SUBJID":"id-14","SITEID":"CHN-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.02692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-29","TRTSDTM":"2019-09-29 11:34:20","TRTEDTM":"2022-02-15 13:58:07","TRT01SDTM":"2019-09-29 11:34:20","TRT01EDTM":"2021-02-15 07:58:07","TRT02SDTM":"2021-02-15 07:58:07","TRT02EDTM":"2022-02-15 13:58:07","AP01SDTM":"2019-09-29 11:34:20","AP01EDTM":"2021-02-15 07:58:07","AP02SDTM":"2021-02-15 07:58:07","AP02EDTM":"2022-02-15 13:58:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":919,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6320,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00179,"AVALU":"g/L","BASE2":2.78763,"BASE":2.91513,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.21416,"PCHG2":7.68266,"CHG":0.08666,"PCHG":2.97276,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-06-27 11:34:20","ADY":272,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-14","SUBJID":"id-14","SITEID":"CHN-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.02692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-29","TRTSDTM":"2019-09-29 11:34:20","TRTEDTM":"2022-02-15 13:58:07","TRT01SDTM":"2019-09-29 11:34:20","TRT01EDTM":"2021-02-15 07:58:07","TRT02SDTM":"2021-02-15 07:58:07","TRT02EDTM":"2022-02-15 13:58:07","AP01SDTM":"2019-09-29 11:34:20","AP01EDTM":"2021-02-15 07:58:07","AP02SDTM":"2021-02-15 07:58:07","AP02EDTM":"2022-02-15 13:58:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":919,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3024,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94849,"AVALU":"g/L","BASE2":2.78763,"BASE":2.91513,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16086,"PCHG2":5.77039,"CHG":0.03335,"PCHG":1.14413,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-03 11:34:20","ADY":431,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-14","SUBJID":"id-14","SITEID":"CHN-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.02692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-29","TRTSDTM":"2019-09-29 11:34:20","TRTEDTM":"2022-02-15 13:58:07","TRT01SDTM":"2019-09-29 11:34:20","TRT01EDTM":"2021-02-15 07:58:07","TRT02SDTM":"2021-02-15 07:58:07","TRT02EDTM":"2022-02-15 13:58:07","AP01SDTM":"2019-09-29 11:34:20","AP01EDTM":"2021-02-15 07:58:07","AP02SDTM":"2021-02-15 07:58:07","AP02EDTM":"2022-02-15 13:58:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":919,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1503,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97279,"AVALU":"g/L","BASE2":2.78763,"BASE":2.91513,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18516,"PCHG2":6.64219,"CHG":0.05766,"PCHG":1.97779,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-30 11:34:20","ADY":548,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-14","SUBJID":"id-14","SITEID":"CHN-15","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.02692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-29","TRTSDTM":"2019-09-29 11:34:20","TRTEDTM":"2022-02-15 13:58:07","TRT01SDTM":"2019-09-29 11:34:20","TRT01EDTM":"2021-02-15 07:58:07","TRT02SDTM":"2021-02-15 07:58:07","TRT02EDTM":"2022-02-15 13:58:07","AP01SDTM":"2019-09-29 11:34:20","AP01EDTM":"2021-02-15 07:58:07","AP02SDTM":"2021-02-15 07:58:07","AP02EDTM":"2022-02-15 13:58:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":871,"DCSREAS":"DEATH","DTHDT":"2022-04-06","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-06","DTHADY":919,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":864,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.59546,"AVALU":"g/L","BASE2":2.78763,"BASE":2.91513,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19217,"PCHG2":-6.89373,"CHG":-0.31968,"PCHG":-10.96608,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-20 11:34:20","ADY":630,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-201","SUBJID":"id-201","SITEID":"CHN-15","AGE":49,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.9068,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-05","TRTSDTM":"2019-03-05 15:24:07","TRTEDTM":"2022-02-19 04:06:48","TRT01SDTM":"2019-03-05 15:24:07","TRT01EDTM":"2021-02-18 22:06:48","TRT02SDTM":"2021-02-18 22:06:48","TRT02EDTM":"2022-02-19 04:06:48","AP01SDTM":"2019-03-05 15:24:07","AP01EDTM":"2021-02-18 22:06:48","AP02SDTM":"2021-02-18 22:06:48","AP02EDTM":"2022-02-19 04:06:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":1082,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":3,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1084,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8158,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.79532,"AVALU":"U/L","BASE2":9.79532,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-06 15:24:07","ADY":215,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-201","SUBJID":"id-201","SITEID":"CHN-15","AGE":49,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.9068,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-05","TRTSDTM":"2019-03-05 15:24:07","TRTEDTM":"2022-02-19 04:06:48","TRT01SDTM":"2019-03-05 15:24:07","TRT01EDTM":"2021-02-18 22:06:48","TRT02SDTM":"2021-02-18 22:06:48","TRT02EDTM":"2022-02-19 04:06:48","AP01SDTM":"2019-03-05 15:24:07","AP01EDTM":"2021-02-18 22:06:48","AP02SDTM":"2021-02-18 22:06:48","AP02EDTM":"2022-02-19 04:06:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":1082,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":3,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1084,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3050,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.07444,"AVALU":"U/L","BASE2":9.79532,"BASE":27.07444,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":17.27913,"PCHG2":176.40194,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-03 15:24:07","ADY":548,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-201","SUBJID":"id-201","SITEID":"CHN-15","AGE":49,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.9068,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-05","TRTSDTM":"2019-03-05 15:24:07","TRTEDTM":"2022-02-19 04:06:48","TRT01SDTM":"2019-03-05 15:24:07","TRT01EDTM":"2021-02-18 22:06:48","TRT02SDTM":"2021-02-18 22:06:48","TRT02EDTM":"2022-02-19 04:06:48","AP01SDTM":"2019-03-05 15:24:07","AP01EDTM":"2021-02-18 22:06:48","AP02SDTM":"2021-02-18 22:06:48","AP02EDTM":"2022-02-19 04:06:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":1082,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":3,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1084,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":322,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.42451,"AVALU":"U/L","BASE2":9.79532,"BASE":27.07444,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.62919,"PCHG2":98.30406,"CHG":-7.64993,"PCHG":-28.25519,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-06 15:24:07","ADY":704,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-201","SUBJID":"id-201","SITEID":"CHN-15","AGE":49,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.9068,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-05","TRTSDTM":"2019-03-05 15:24:07","TRTEDTM":"2022-02-19 04:06:48","TRT01SDTM":"2019-03-05 15:24:07","TRT01EDTM":"2021-02-18 22:06:48","TRT02SDTM":"2021-02-18 22:06:48","TRT02EDTM":"2022-02-19 04:06:48","AP01SDTM":"2019-03-05 15:24:07","AP01EDTM":"2021-02-18 22:06:48","AP02SDTM":"2021-02-18 22:06:48","AP02EDTM":"2022-02-19 04:06:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":1082,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":3,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1084,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3425,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.37306,"AVALU":"U/L","BASE2":9.79532,"BASE":27.07444,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.42225,"PCHG2":-14.51971,"CHG":-18.70138,"PCHG":-69.07392,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-22 15:24:07","ADY":809,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-201","SUBJID":"id-201","SITEID":"CHN-15","AGE":49,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.9068,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-05","TRTSDTM":"2019-03-05 15:24:07","TRTEDTM":"2022-02-19 04:06:48","TRT01SDTM":"2019-03-05 15:24:07","TRT01EDTM":"2021-02-18 22:06:48","TRT02SDTM":"2021-02-18 22:06:48","TRT02EDTM":"2022-02-19 04:06:48","AP01SDTM":"2019-03-05 15:24:07","AP01EDTM":"2021-02-18 22:06:48","AP02SDTM":"2021-02-18 22:06:48","AP02EDTM":"2022-02-19 04:06:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":1082,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":3,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1084,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4223,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.52922,"AVALU":"U/L","BASE2":9.79532,"BASE":27.07444,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.73391,"PCHG2":99.37306,"CHG":-7.54522,"PCHG":-27.86843,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-25 15:24:07","ADY":965,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-201","SUBJID":"id-201","SITEID":"CHN-15","AGE":49,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.9068,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-05","TRTSDTM":"2019-03-05 15:24:07","TRTEDTM":"2022-02-19 04:06:48","TRT01SDTM":"2019-03-05 15:24:07","TRT01EDTM":"2021-02-18 22:06:48","TRT02SDTM":"2021-02-18 22:06:48","TRT02EDTM":"2022-02-19 04:06:48","AP01SDTM":"2019-03-05 15:24:07","AP01EDTM":"2021-02-18 22:06:48","AP02SDTM":"2021-02-18 22:06:48","AP02EDTM":"2022-02-19 04:06:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":1082,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":3,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1084,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1302,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.3443,"AVALU":"U/L","BASE2":9.79532,"BASE":27.07444,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.54899,"PCHG2":138.32109,"CHG":-3.73014,"PCHG":-13.77734,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-07 15:24:07","ADY":1008,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-201","SUBJID":"id-201","SITEID":"CHN-15","AGE":49,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.9068,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-05","TRTSDTM":"2019-03-05 15:24:07","TRTEDTM":"2022-02-19 04:06:48","TRT01SDTM":"2019-03-05 15:24:07","TRT01EDTM":"2021-02-18 22:06:48","TRT02SDTM":"2021-02-18 22:06:48","TRT02EDTM":"2022-02-19 04:06:48","AP01SDTM":"2019-03-05 15:24:07","AP01EDTM":"2021-02-18 22:06:48","AP02SDTM":"2021-02-18 22:06:48","AP02EDTM":"2022-02-19 04:06:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":1082,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":3,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1084,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3199,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.09114,"AVALU":"U/L","BASE2":9.79532,"BASE":27.07444,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.29582,"PCHG2":125.52759,"CHG":-4.9833,"PCHG":-18.40593,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-18 15:24:07","ADY":1019,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-201","SUBJID":"id-201","SITEID":"CHN-15","AGE":49,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.9068,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-05","TRTSDTM":"2019-03-05 15:24:07","TRTEDTM":"2022-02-19 04:06:48","TRT01SDTM":"2019-03-05 15:24:07","TRT01EDTM":"2021-02-18 22:06:48","TRT02SDTM":"2021-02-18 22:06:48","TRT02EDTM":"2022-02-19 04:06:48","AP01SDTM":"2019-03-05 15:24:07","AP01EDTM":"2021-02-18 22:06:48","AP02SDTM":"2021-02-18 22:06:48","AP02EDTM":"2022-02-19 04:06:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":1082,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":3,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1084,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5163,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.08365,"AVALU":"mg/L","BASE2":8.08365,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-06 15:24:07","ADY":215,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-201","SUBJID":"id-201","SITEID":"CHN-15","AGE":49,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.9068,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-05","TRTSDTM":"2019-03-05 15:24:07","TRTEDTM":"2022-02-19 04:06:48","TRT01SDTM":"2019-03-05 15:24:07","TRT01EDTM":"2021-02-18 22:06:48","TRT02SDTM":"2021-02-18 22:06:48","TRT02EDTM":"2022-02-19 04:06:48","AP01SDTM":"2019-03-05 15:24:07","AP01EDTM":"2021-02-18 22:06:48","AP02SDTM":"2021-02-18 22:06:48","AP02EDTM":"2022-02-19 04:06:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":1082,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":3,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1084,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":658,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.47501,"AVALU":"mg/L","BASE2":8.08365,"BASE":8.47501,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.39137,"PCHG2":4.84145,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-03 15:24:07","ADY":548,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-201","SUBJID":"id-201","SITEID":"CHN-15","AGE":49,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.9068,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-05","TRTSDTM":"2019-03-05 15:24:07","TRTEDTM":"2022-02-19 04:06:48","TRT01SDTM":"2019-03-05 15:24:07","TRT01EDTM":"2021-02-18 22:06:48","TRT02SDTM":"2021-02-18 22:06:48","TRT02EDTM":"2022-02-19 04:06:48","AP01SDTM":"2019-03-05 15:24:07","AP01EDTM":"2021-02-18 22:06:48","AP02SDTM":"2021-02-18 22:06:48","AP02EDTM":"2022-02-19 04:06:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":1082,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":3,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1084,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4547,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.47993,"AVALU":"mg/L","BASE2":8.08365,"BASE":8.47501,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.39629,"PCHG2":29.64365,"CHG":2.00492,"PCHG":23.65687,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-02-06 15:24:07","ADY":704,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-201","SUBJID":"id-201","SITEID":"CHN-15","AGE":49,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.9068,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-05","TRTSDTM":"2019-03-05 15:24:07","TRTEDTM":"2022-02-19 04:06:48","TRT01SDTM":"2019-03-05 15:24:07","TRT01EDTM":"2021-02-18 22:06:48","TRT02SDTM":"2021-02-18 22:06:48","TRT02EDTM":"2022-02-19 04:06:48","AP01SDTM":"2019-03-05 15:24:07","AP01EDTM":"2021-02-18 22:06:48","AP02SDTM":"2021-02-18 22:06:48","AP02EDTM":"2022-02-19 04:06:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":1082,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":3,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1084,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":848,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.29842,"AVALU":"mg/L","BASE2":8.08365,"BASE":8.47501,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.21477,"PCHG2":2.65686,"CHG":-0.17659,"PCHG":-2.08371,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-22 15:24:07","ADY":809,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-201","SUBJID":"id-201","SITEID":"CHN-15","AGE":49,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.9068,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-05","TRTSDTM":"2019-03-05 15:24:07","TRTEDTM":"2022-02-19 04:06:48","TRT01SDTM":"2019-03-05 15:24:07","TRT01EDTM":"2021-02-18 22:06:48","TRT02SDTM":"2021-02-18 22:06:48","TRT02EDTM":"2022-02-19 04:06:48","AP01SDTM":"2019-03-05 15:24:07","AP01EDTM":"2021-02-18 22:06:48","AP02SDTM":"2021-02-18 22:06:48","AP02EDTM":"2022-02-19 04:06:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":1082,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":3,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1084,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2884,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.41891,"AVALU":"mg/L","BASE2":8.08365,"BASE":8.47501,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.33527,"PCHG2":4.1475,"CHG":-0.0561,"PCHG":-0.66191,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-25 15:24:07","ADY":965,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-201","SUBJID":"id-201","SITEID":"CHN-15","AGE":49,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.9068,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-05","TRTSDTM":"2019-03-05 15:24:07","TRTEDTM":"2022-02-19 04:06:48","TRT01SDTM":"2019-03-05 15:24:07","TRT01EDTM":"2021-02-18 22:06:48","TRT02SDTM":"2021-02-18 22:06:48","TRT02EDTM":"2022-02-19 04:06:48","AP01SDTM":"2019-03-05 15:24:07","AP01EDTM":"2021-02-18 22:06:48","AP02SDTM":"2021-02-18 22:06:48","AP02EDTM":"2022-02-19 04:06:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":1082,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":3,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1084,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7264,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.21116,"AVALU":"mg/L","BASE2":8.08365,"BASE":8.47501,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.87249,"PCHG2":-10.79324,"CHG":-1.26385,"PCHG":-14.9127,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-12-07 15:24:07","ADY":1008,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-201","SUBJID":"id-201","SITEID":"CHN-15","AGE":49,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.9068,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-05","TRTSDTM":"2019-03-05 15:24:07","TRTEDTM":"2022-02-19 04:06:48","TRT01SDTM":"2019-03-05 15:24:07","TRT01EDTM":"2021-02-18 22:06:48","TRT02SDTM":"2021-02-18 22:06:48","TRT02EDTM":"2022-02-19 04:06:48","AP01SDTM":"2019-03-05 15:24:07","AP01EDTM":"2021-02-18 22:06:48","AP02SDTM":"2021-02-18 22:06:48","AP02EDTM":"2022-02-19 04:06:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":1082,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":3,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1084,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2594,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.47806,"AVALU":"mg/L","BASE2":8.08365,"BASE":8.47501,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.60558,"PCHG2":-7.49146,"CHG":-0.99695,"PCHG":-11.76338,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-12-18 15:24:07","ADY":1019,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-201","SUBJID":"id-201","SITEID":"CHN-15","AGE":49,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.9068,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-05","TRTSDTM":"2019-03-05 15:24:07","TRTEDTM":"2022-02-19 04:06:48","TRT01SDTM":"2019-03-05 15:24:07","TRT01EDTM":"2021-02-18 22:06:48","TRT02SDTM":"2021-02-18 22:06:48","TRT02EDTM":"2022-02-19 04:06:48","AP01SDTM":"2019-03-05 15:24:07","AP01EDTM":"2021-02-18 22:06:48","AP02SDTM":"2021-02-18 22:06:48","AP02EDTM":"2022-02-19 04:06:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":1082,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":3,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1084,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3650,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85209,"AVALU":"g/L","BASE2":2.85209,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-06 15:24:07","ADY":215,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-201","SUBJID":"id-201","SITEID":"CHN-15","AGE":49,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.9068,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-05","TRTSDTM":"2019-03-05 15:24:07","TRTEDTM":"2022-02-19 04:06:48","TRT01SDTM":"2019-03-05 15:24:07","TRT01EDTM":"2021-02-18 22:06:48","TRT02SDTM":"2021-02-18 22:06:48","TRT02EDTM":"2022-02-19 04:06:48","AP01SDTM":"2019-03-05 15:24:07","AP01EDTM":"2021-02-18 22:06:48","AP02SDTM":"2021-02-18 22:06:48","AP02EDTM":"2022-02-19 04:06:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":1082,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":3,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1084,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4831,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96461,"AVALU":"g/L","BASE2":2.85209,"BASE":2.96461,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.11251,"PCHG2":3.94496,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-03 15:24:07","ADY":548,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-201","SUBJID":"id-201","SITEID":"CHN-15","AGE":49,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.9068,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-05","TRTSDTM":"2019-03-05 15:24:07","TRTEDTM":"2022-02-19 04:06:48","TRT01SDTM":"2019-03-05 15:24:07","TRT01EDTM":"2021-02-18 22:06:48","TRT02SDTM":"2021-02-18 22:06:48","TRT02EDTM":"2022-02-19 04:06:48","AP01SDTM":"2019-03-05 15:24:07","AP01EDTM":"2021-02-18 22:06:48","AP02SDTM":"2021-02-18 22:06:48","AP02EDTM":"2022-02-19 04:06:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":1082,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":3,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1084,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6823,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87164,"AVALU":"g/L","BASE2":2.85209,"BASE":2.96461,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01955,"PCHG2":0.68547,"CHG":-0.09296,"PCHG":-3.13578,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-06 15:24:07","ADY":704,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-201","SUBJID":"id-201","SITEID":"CHN-15","AGE":49,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.9068,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-05","TRTSDTM":"2019-03-05 15:24:07","TRTEDTM":"2022-02-19 04:06:48","TRT01SDTM":"2019-03-05 15:24:07","TRT01EDTM":"2021-02-18 22:06:48","TRT02SDTM":"2021-02-18 22:06:48","TRT02EDTM":"2022-02-19 04:06:48","AP01SDTM":"2019-03-05 15:24:07","AP01EDTM":"2021-02-18 22:06:48","AP02SDTM":"2021-02-18 22:06:48","AP02EDTM":"2022-02-19 04:06:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":1082,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":3,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1084,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1969,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82117,"AVALU":"g/L","BASE2":2.85209,"BASE":2.96461,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03093,"PCHG2":-1.08441,"CHG":-0.14344,"PCHG":-4.8385,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-22 15:24:07","ADY":809,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-201","SUBJID":"id-201","SITEID":"CHN-15","AGE":49,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.9068,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-05","TRTSDTM":"2019-03-05 15:24:07","TRTEDTM":"2022-02-19 04:06:48","TRT01SDTM":"2019-03-05 15:24:07","TRT01EDTM":"2021-02-18 22:06:48","TRT02SDTM":"2021-02-18 22:06:48","TRT02EDTM":"2022-02-19 04:06:48","AP01SDTM":"2019-03-05 15:24:07","AP01EDTM":"2021-02-18 22:06:48","AP02SDTM":"2021-02-18 22:06:48","AP02EDTM":"2022-02-19 04:06:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":1082,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":3,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1084,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1095,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98376,"AVALU":"g/L","BASE2":2.85209,"BASE":2.96461,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13166,"PCHG2":4.61633,"CHG":0.01915,"PCHG":0.64589,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-25 15:24:07","ADY":965,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-201","SUBJID":"id-201","SITEID":"CHN-15","AGE":49,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.9068,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-05","TRTSDTM":"2019-03-05 15:24:07","TRTEDTM":"2022-02-19 04:06:48","TRT01SDTM":"2019-03-05 15:24:07","TRT01EDTM":"2021-02-18 22:06:48","TRT02SDTM":"2021-02-18 22:06:48","TRT02EDTM":"2022-02-19 04:06:48","AP01SDTM":"2019-03-05 15:24:07","AP01EDTM":"2021-02-18 22:06:48","AP02SDTM":"2021-02-18 22:06:48","AP02EDTM":"2022-02-19 04:06:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":1082,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":3,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1084,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6519,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8825,"AVALU":"g/L","BASE2":2.85209,"BASE":2.96461,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0304,"PCHG2":1.0659,"CHG":-0.08211,"PCHG":-2.76979,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-07 15:24:07","ADY":1008,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-201","SUBJID":"id-201","SITEID":"CHN-15","AGE":49,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.9068,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-05","TRTSDTM":"2019-03-05 15:24:07","TRTEDTM":"2022-02-19 04:06:48","TRT01SDTM":"2019-03-05 15:24:07","TRT01EDTM":"2021-02-18 22:06:48","TRT02SDTM":"2021-02-18 22:06:48","TRT02EDTM":"2022-02-19 04:06:48","AP01SDTM":"2019-03-05 15:24:07","AP01EDTM":"2021-02-18 22:06:48","AP02SDTM":"2021-02-18 22:06:48","AP02EDTM":"2022-02-19 04:06:48","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":1082,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":3,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1084,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3265,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83173,"AVALU":"g/L","BASE2":2.85209,"BASE":2.96461,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02037,"PCHG2":-0.71411,"CHG":-0.13288,"PCHG":-4.48225,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-18 15:24:07","ADY":1019,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-245","SUBJID":"id-245","SITEID":"CHN-15","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.68285,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-25","TRTSDTM":"2019-03-29 02:27:00","TRTEDTM":"2022-02-17 04:42:51","TRT01SDTM":"2019-03-29 02:27:00","TRT01EDTM":"2021-02-16 22:42:51","TRT02SDTM":"2021-02-16 22:42:51","TRT02EDTM":"2022-02-17 04:42:51","AP01SDTM":"2019-03-29 02:27:00","AP01EDTM":"2021-02-16 22:42:51","AP02SDTM":"2021-02-16 22:42:51","AP02EDTM":"2022-02-17 04:42:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1057,"DCSREAS":"DEATH","DTHDT":"2022-02-18","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-18","DTHADY":1056,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6674,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.21221,"AVALU":"U/L","BASE2":26.21221,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-04-08 02:27:00","ADY":10,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-245","SUBJID":"id-245","SITEID":"CHN-15","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.68285,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-25","TRTSDTM":"2019-03-29 02:27:00","TRTEDTM":"2022-02-17 04:42:51","TRT01SDTM":"2019-03-29 02:27:00","TRT01EDTM":"2021-02-16 22:42:51","TRT02SDTM":"2021-02-16 22:42:51","TRT02EDTM":"2022-02-17 04:42:51","AP01SDTM":"2019-03-29 02:27:00","AP01EDTM":"2021-02-16 22:42:51","AP02SDTM":"2021-02-16 22:42:51","AP02EDTM":"2022-02-17 04:42:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1057,"DCSREAS":"DEATH","DTHDT":"2022-02-18","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-18","DTHADY":1056,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4971,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.76172,"AVALU":"U/L","BASE2":26.21221,"BASE":25.76172,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.45049,"PCHG2":-1.71862,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-06 02:27:00","ADY":222,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-245","SUBJID":"id-245","SITEID":"CHN-15","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.68285,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-25","TRTSDTM":"2019-03-29 02:27:00","TRTEDTM":"2022-02-17 04:42:51","TRT01SDTM":"2019-03-29 02:27:00","TRT01EDTM":"2021-02-16 22:42:51","TRT02SDTM":"2021-02-16 22:42:51","TRT02EDTM":"2022-02-17 04:42:51","AP01SDTM":"2019-03-29 02:27:00","AP01EDTM":"2021-02-16 22:42:51","AP02SDTM":"2021-02-16 22:42:51","AP02EDTM":"2022-02-17 04:42:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1057,"DCSREAS":"DEATH","DTHDT":"2022-02-18","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-18","DTHADY":1056,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5107,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.33795,"AVALU":"U/L","BASE2":26.21221,"BASE":25.76172,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.12573,"PCHG2":4.29469,"CHG":1.57622,"PCHG":6.11846,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-10 02:27:00","ADY":347,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-245","SUBJID":"id-245","SITEID":"CHN-15","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.68285,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-25","TRTSDTM":"2019-03-29 02:27:00","TRTEDTM":"2022-02-17 04:42:51","TRT01SDTM":"2019-03-29 02:27:00","TRT01EDTM":"2021-02-16 22:42:51","TRT02SDTM":"2021-02-16 22:42:51","TRT02EDTM":"2022-02-17 04:42:51","AP01SDTM":"2019-03-29 02:27:00","AP01EDTM":"2021-02-16 22:42:51","AP02SDTM":"2021-02-16 22:42:51","AP02EDTM":"2022-02-17 04:42:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1057,"DCSREAS":"DEATH","DTHDT":"2022-02-18","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-18","DTHADY":1056,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7166,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.10445,"AVALU":"U/L","BASE2":26.21221,"BASE":25.76172,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.10776,"PCHG2":-34.74625,"CHG":-8.65727,"PCHG":-33.60518,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-05 02:27:00","ADY":434,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-245","SUBJID":"id-245","SITEID":"CHN-15","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.68285,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-25","TRTSDTM":"2019-03-29 02:27:00","TRTEDTM":"2022-02-17 04:42:51","TRT01SDTM":"2019-03-29 02:27:00","TRT01EDTM":"2021-02-16 22:42:51","TRT02SDTM":"2021-02-16 22:42:51","TRT02EDTM":"2022-02-17 04:42:51","AP01SDTM":"2019-03-29 02:27:00","AP01EDTM":"2021-02-16 22:42:51","AP02SDTM":"2021-02-16 22:42:51","AP02EDTM":"2022-02-17 04:42:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1057,"DCSREAS":"DEATH","DTHDT":"2022-02-18","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-18","DTHADY":1056,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5482,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.11231,"AVALU":"U/L","BASE2":26.21221,"BASE":25.76172,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.0999,"PCHG2":-11.82616,"CHG":-2.64941,"PCHG":-10.28429,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-04 02:27:00","ADY":767,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-245","SUBJID":"id-245","SITEID":"CHN-15","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.68285,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-25","TRTSDTM":"2019-03-29 02:27:00","TRTEDTM":"2022-02-17 04:42:51","TRT01SDTM":"2019-03-29 02:27:00","TRT01EDTM":"2021-02-16 22:42:51","TRT02SDTM":"2021-02-16 22:42:51","TRT02EDTM":"2022-02-17 04:42:51","AP01SDTM":"2019-03-29 02:27:00","AP01EDTM":"2021-02-16 22:42:51","AP02SDTM":"2021-02-16 22:42:51","AP02EDTM":"2022-02-17 04:42:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1057,"DCSREAS":"DEATH","DTHDT":"2022-02-18","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-18","DTHADY":1056,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5232,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.47214,"AVALU":"U/L","BASE2":26.21221,"BASE":25.76172,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.25992,"PCHG2":31.51174,"CHG":8.71041,"PCHG":33.81144,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-12 02:27:00","ADY":898,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-245","SUBJID":"id-245","SITEID":"CHN-15","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.68285,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-25","TRTSDTM":"2019-03-29 02:27:00","TRTEDTM":"2022-02-17 04:42:51","TRT01SDTM":"2019-03-29 02:27:00","TRT01EDTM":"2021-02-16 22:42:51","TRT02SDTM":"2021-02-16 22:42:51","TRT02EDTM":"2022-02-17 04:42:51","AP01SDTM":"2019-03-29 02:27:00","AP01EDTM":"2021-02-16 22:42:51","AP02SDTM":"2021-02-16 22:42:51","AP02EDTM":"2022-02-17 04:42:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1057,"DCSREAS":"DEATH","DTHDT":"2022-02-18","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-18","DTHADY":1056,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4035,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.09091,"AVALU":"U/L","BASE2":26.21221,"BASE":25.76172,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.1213,"PCHG2":-38.61292,"CHG":-9.67081,"PCHG":-37.53946,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-21 02:27:00","ADY":1029,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-245","SUBJID":"id-245","SITEID":"CHN-15","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.68285,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-25","TRTSDTM":"2019-03-29 02:27:00","TRTEDTM":"2022-02-17 04:42:51","TRT01SDTM":"2019-03-29 02:27:00","TRT01EDTM":"2021-02-16 22:42:51","TRT02SDTM":"2021-02-16 22:42:51","TRT02EDTM":"2022-02-17 04:42:51","AP01SDTM":"2019-03-29 02:27:00","AP01EDTM":"2021-02-16 22:42:51","AP02SDTM":"2021-02-16 22:42:51","AP02EDTM":"2022-02-17 04:42:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1057,"DCSREAS":"DEATH","DTHDT":"2022-02-18","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-18","DTHADY":1056,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":197,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.65388,"AVALU":"mg/L","BASE2":8.65388,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-04-08 02:27:00","ADY":10,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-245","SUBJID":"id-245","SITEID":"CHN-15","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.68285,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-25","TRTSDTM":"2019-03-29 02:27:00","TRTEDTM":"2022-02-17 04:42:51","TRT01SDTM":"2019-03-29 02:27:00","TRT01EDTM":"2021-02-16 22:42:51","TRT02SDTM":"2021-02-16 22:42:51","TRT02EDTM":"2022-02-17 04:42:51","AP01SDTM":"2019-03-29 02:27:00","AP01EDTM":"2021-02-16 22:42:51","AP02SDTM":"2021-02-16 22:42:51","AP02EDTM":"2022-02-17 04:42:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1057,"DCSREAS":"DEATH","DTHDT":"2022-02-18","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-18","DTHADY":1056,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2967,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.16525,"AVALU":"mg/L","BASE2":8.65388,"BASE":8.16525,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.48864,"PCHG2":-5.64643,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-06 02:27:00","ADY":222,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-245","SUBJID":"id-245","SITEID":"CHN-15","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.68285,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-25","TRTSDTM":"2019-03-29 02:27:00","TRTEDTM":"2022-02-17 04:42:51","TRT01SDTM":"2019-03-29 02:27:00","TRT01EDTM":"2021-02-16 22:42:51","TRT02SDTM":"2021-02-16 22:42:51","TRT02EDTM":"2022-02-17 04:42:51","AP01SDTM":"2019-03-29 02:27:00","AP01EDTM":"2021-02-16 22:42:51","AP02SDTM":"2021-02-16 22:42:51","AP02EDTM":"2022-02-17 04:42:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1057,"DCSREAS":"DEATH","DTHDT":"2022-02-18","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-18","DTHADY":1056,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3927,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.94347,"AVALU":"mg/L","BASE2":8.65388,"BASE":8.16525,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.28959,"PCHG2":14.90184,"CHG":1.77822,"PCHG":21.77794,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-10 02:27:00","ADY":347,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-245","SUBJID":"id-245","SITEID":"CHN-15","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.68285,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-25","TRTSDTM":"2019-03-29 02:27:00","TRTEDTM":"2022-02-17 04:42:51","TRT01SDTM":"2019-03-29 02:27:00","TRT01EDTM":"2021-02-16 22:42:51","TRT02SDTM":"2021-02-16 22:42:51","TRT02EDTM":"2022-02-17 04:42:51","AP01SDTM":"2019-03-29 02:27:00","AP01EDTM":"2021-02-16 22:42:51","AP02SDTM":"2021-02-16 22:42:51","AP02EDTM":"2022-02-17 04:42:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1057,"DCSREAS":"DEATH","DTHDT":"2022-02-18","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-18","DTHADY":1056,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3608,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.07016,"AVALU":"mg/L","BASE2":8.65388,"BASE":8.16525,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.58372,"PCHG2":-18.30069,"CHG":-1.09508,"PCHG":-13.41153,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-06-05 02:27:00","ADY":434,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-245","SUBJID":"id-245","SITEID":"CHN-15","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.68285,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-25","TRTSDTM":"2019-03-29 02:27:00","TRTEDTM":"2022-02-17 04:42:51","TRT01SDTM":"2019-03-29 02:27:00","TRT01EDTM":"2021-02-16 22:42:51","TRT02SDTM":"2021-02-16 22:42:51","TRT02EDTM":"2022-02-17 04:42:51","AP01SDTM":"2019-03-29 02:27:00","AP01EDTM":"2021-02-16 22:42:51","AP02SDTM":"2021-02-16 22:42:51","AP02EDTM":"2022-02-17 04:42:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1057,"DCSREAS":"DEATH","DTHDT":"2022-02-18","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-18","DTHADY":1056,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8387,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.38782,"AVALU":"mg/L","BASE2":8.65388,"BASE":8.16525,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.26606,"PCHG2":-3.0745,"CHG":0.22257,"PCHG":2.72584,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-04 02:27:00","ADY":767,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-245","SUBJID":"id-245","SITEID":"CHN-15","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.68285,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-25","TRTSDTM":"2019-03-29 02:27:00","TRTEDTM":"2022-02-17 04:42:51","TRT01SDTM":"2019-03-29 02:27:00","TRT01EDTM":"2021-02-16 22:42:51","TRT02SDTM":"2021-02-16 22:42:51","TRT02EDTM":"2022-02-17 04:42:51","AP01SDTM":"2019-03-29 02:27:00","AP01EDTM":"2021-02-16 22:42:51","AP02SDTM":"2021-02-16 22:42:51","AP02EDTM":"2022-02-17 04:42:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1057,"DCSREAS":"DEATH","DTHDT":"2022-02-18","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-18","DTHADY":1056,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1185,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.54854,"AVALU":"mg/L","BASE2":8.65388,"BASE":8.16525,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10534,"PCHG2":-1.21728,"CHG":0.38329,"PCHG":4.6942,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-12 02:27:00","ADY":898,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-245","SUBJID":"id-245","SITEID":"CHN-15","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.68285,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-25","TRTSDTM":"2019-03-29 02:27:00","TRTEDTM":"2022-02-17 04:42:51","TRT01SDTM":"2019-03-29 02:27:00","TRT01EDTM":"2021-02-16 22:42:51","TRT02SDTM":"2021-02-16 22:42:51","TRT02EDTM":"2022-02-17 04:42:51","AP01SDTM":"2019-03-29 02:27:00","AP01EDTM":"2021-02-16 22:42:51","AP02SDTM":"2021-02-16 22:42:51","AP02EDTM":"2022-02-17 04:42:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1057,"DCSREAS":"DEATH","DTHDT":"2022-02-18","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-18","DTHADY":1056,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2318,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.01439,"AVALU":"mg/L","BASE2":8.65388,"BASE":8.16525,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.63949,"PCHG2":-7.38964,"CHG":-0.15086,"PCHG":-1.84753,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-21 02:27:00","ADY":1029,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-245","SUBJID":"id-245","SITEID":"CHN-15","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.68285,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-25","TRTSDTM":"2019-03-29 02:27:00","TRTEDTM":"2022-02-17 04:42:51","TRT01SDTM":"2019-03-29 02:27:00","TRT01EDTM":"2021-02-16 22:42:51","TRT02SDTM":"2021-02-16 22:42:51","TRT02EDTM":"2022-02-17 04:42:51","AP01SDTM":"2019-03-29 02:27:00","AP01EDTM":"2021-02-16 22:42:51","AP02SDTM":"2021-02-16 22:42:51","AP02EDTM":"2022-02-17 04:42:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1057,"DCSREAS":"DEATH","DTHDT":"2022-02-18","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-18","DTHADY":1056,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7074,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99283,"AVALU":"g/L","BASE2":2.99283,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-04-08 02:27:00","ADY":10,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-245","SUBJID":"id-245","SITEID":"CHN-15","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.68285,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-25","TRTSDTM":"2019-03-29 02:27:00","TRTEDTM":"2022-02-17 04:42:51","TRT01SDTM":"2019-03-29 02:27:00","TRT01EDTM":"2021-02-16 22:42:51","TRT02SDTM":"2021-02-16 22:42:51","TRT02EDTM":"2022-02-17 04:42:51","AP01SDTM":"2019-03-29 02:27:00","AP01EDTM":"2021-02-16 22:42:51","AP02SDTM":"2021-02-16 22:42:51","AP02EDTM":"2022-02-17 04:42:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1057,"DCSREAS":"DEATH","DTHDT":"2022-02-18","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-18","DTHADY":1056,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":337,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9684,"AVALU":"g/L","BASE2":2.99283,"BASE":2.9684,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.02443,"PCHG2":-0.81624,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-06 02:27:00","ADY":222,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-245","SUBJID":"id-245","SITEID":"CHN-15","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.68285,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-25","TRTSDTM":"2019-03-29 02:27:00","TRTEDTM":"2022-02-17 04:42:51","TRT01SDTM":"2019-03-29 02:27:00","TRT01EDTM":"2021-02-16 22:42:51","TRT02SDTM":"2021-02-16 22:42:51","TRT02EDTM":"2022-02-17 04:42:51","AP01SDTM":"2019-03-29 02:27:00","AP01EDTM":"2021-02-16 22:42:51","AP02SDTM":"2021-02-16 22:42:51","AP02EDTM":"2022-02-17 04:42:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1057,"DCSREAS":"DEATH","DTHDT":"2022-02-18","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-18","DTHADY":1056,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6109,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98923,"AVALU":"g/L","BASE2":2.99283,"BASE":2.9684,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0036,"PCHG2":-0.1203,"CHG":0.02083,"PCHG":0.70167,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-10 02:27:00","ADY":347,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-245","SUBJID":"id-245","SITEID":"CHN-15","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.68285,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-25","TRTSDTM":"2019-03-29 02:27:00","TRTEDTM":"2022-02-17 04:42:51","TRT01SDTM":"2019-03-29 02:27:00","TRT01EDTM":"2021-02-16 22:42:51","TRT02SDTM":"2021-02-16 22:42:51","TRT02EDTM":"2022-02-17 04:42:51","AP01SDTM":"2019-03-29 02:27:00","AP01EDTM":"2021-02-16 22:42:51","AP02SDTM":"2021-02-16 22:42:51","AP02EDTM":"2022-02-17 04:42:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1057,"DCSREAS":"DEATH","DTHDT":"2022-02-18","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-18","DTHADY":1056,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":948,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8311,"AVALU":"g/L","BASE2":2.99283,"BASE":2.9684,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16173,"PCHG2":-5.40382,"CHG":-0.1373,"PCHG":-4.62533,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-05 02:27:00","ADY":434,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-245","SUBJID":"id-245","SITEID":"CHN-15","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.68285,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-25","TRTSDTM":"2019-03-29 02:27:00","TRTEDTM":"2022-02-17 04:42:51","TRT01SDTM":"2019-03-29 02:27:00","TRT01EDTM":"2021-02-16 22:42:51","TRT02SDTM":"2021-02-16 22:42:51","TRT02EDTM":"2022-02-17 04:42:51","AP01SDTM":"2019-03-29 02:27:00","AP01EDTM":"2021-02-16 22:42:51","AP02SDTM":"2021-02-16 22:42:51","AP02EDTM":"2022-02-17 04:42:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1057,"DCSREAS":"DEATH","DTHDT":"2022-02-18","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-18","DTHADY":1056,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":944,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74904,"AVALU":"g/L","BASE2":2.99283,"BASE":2.9684,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.24378,"PCHG2":-8.14561,"CHG":-0.21936,"PCHG":-7.38969,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-04 02:27:00","ADY":767,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-245","SUBJID":"id-245","SITEID":"CHN-15","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.68285,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-25","TRTSDTM":"2019-03-29 02:27:00","TRTEDTM":"2022-02-17 04:42:51","TRT01SDTM":"2019-03-29 02:27:00","TRT01EDTM":"2021-02-16 22:42:51","TRT02SDTM":"2021-02-16 22:42:51","TRT02EDTM":"2022-02-17 04:42:51","AP01SDTM":"2019-03-29 02:27:00","AP01EDTM":"2021-02-16 22:42:51","AP02SDTM":"2021-02-16 22:42:51","AP02EDTM":"2022-02-17 04:42:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1057,"DCSREAS":"DEATH","DTHDT":"2022-02-18","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-18","DTHADY":1056,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4305,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92188,"AVALU":"g/L","BASE2":2.99283,"BASE":2.9684,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07095,"PCHG2":-2.37053,"CHG":-0.04652,"PCHG":-1.56708,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-12 02:27:00","ADY":898,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-245","SUBJID":"id-245","SITEID":"CHN-15","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.68285,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-25","TRTSDTM":"2019-03-29 02:27:00","TRTEDTM":"2022-02-17 04:42:51","TRT01SDTM":"2019-03-29 02:27:00","TRT01EDTM":"2021-02-16 22:42:51","TRT02SDTM":"2021-02-16 22:42:51","TRT02EDTM":"2022-02-17 04:42:51","AP01SDTM":"2019-03-29 02:27:00","AP01EDTM":"2021-02-16 22:42:51","AP02SDTM":"2021-02-16 22:42:51","AP02EDTM":"2022-02-17 04:42:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1057,"DCSREAS":"DEATH","DTHDT":"2022-02-18","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":1,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-18","DTHADY":1056,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2810,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85536,"AVALU":"g/L","BASE2":2.99283,"BASE":2.9684,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13746,"PCHG2":-4.59304,"CHG":-0.11303,"PCHG":-3.80788,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-21 02:27:00","ADY":1029,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-262","SUBJID":"id-262","SITEID":"CHN-15","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.05546,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-02-26","TRTSDTM":"2019-02-26 09:05:10","TRTEDTM":"2022-02-26 03:05:10","TRT01SDTM":"2019-02-26 09:05:10","TRT01EDTM":"2021-02-25 21:05:10","TRT02SDTM":"2021-02-25 21:05:10","TRT02EDTM":"2022-02-26 03:05:10","AP01SDTM":"2019-02-26 09:05:10","AP01EDTM":"2021-02-25 21:05:10","AP02SDTM":"2021-02-25 21:05:10","AP02EDTM":"2022-02-26 03:05:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-26","EOSDY":1096,"LSTALVDT":"2022-03-17","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6652,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.83643,"AVALU":"U/L","BASE2":19.83643,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-02-28 09:05:10","ADY":2,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-262","SUBJID":"id-262","SITEID":"CHN-15","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.05546,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-02-26","TRTSDTM":"2019-02-26 09:05:10","TRTEDTM":"2022-02-26 03:05:10","TRT01SDTM":"2019-02-26 09:05:10","TRT01EDTM":"2021-02-25 21:05:10","TRT02SDTM":"2021-02-25 21:05:10","TRT02EDTM":"2022-02-26 03:05:10","AP01SDTM":"2019-02-26 09:05:10","AP01EDTM":"2021-02-25 21:05:10","AP02SDTM":"2021-02-25 21:05:10","AP02EDTM":"2022-02-26 03:05:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-26","EOSDY":1096,"LSTALVDT":"2022-03-17","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":544,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":37.23164,"AVALU":"U/L","BASE2":19.83643,"BASE":37.23164,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":17.3952,"PCHG2":87.6932,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-06-30 09:05:10","ADY":124,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-262","SUBJID":"id-262","SITEID":"CHN-15","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.05546,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-02-26","TRTSDTM":"2019-02-26 09:05:10","TRTEDTM":"2022-02-26 03:05:10","TRT01SDTM":"2019-02-26 09:05:10","TRT01EDTM":"2021-02-25 21:05:10","TRT02SDTM":"2021-02-25 21:05:10","TRT02EDTM":"2022-02-26 03:05:10","AP01SDTM":"2019-02-26 09:05:10","AP01EDTM":"2021-02-25 21:05:10","AP02SDTM":"2021-02-25 21:05:10","AP02EDTM":"2022-02-26 03:05:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-26","EOSDY":1096,"LSTALVDT":"2022-03-17","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5495,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.95354,"AVALU":"U/L","BASE2":19.83643,"BASE":37.23164,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.11711,"PCHG2":40.92018,"CHG":-9.2781,"PCHG":-24.91993,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-17 09:05:10","ADY":141,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-262","SUBJID":"id-262","SITEID":"CHN-15","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.05546,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-02-26","TRTSDTM":"2019-02-26 09:05:10","TRTEDTM":"2022-02-26 03:05:10","TRT01SDTM":"2019-02-26 09:05:10","TRT01EDTM":"2021-02-25 21:05:10","TRT02SDTM":"2021-02-25 21:05:10","TRT02EDTM":"2022-02-26 03:05:10","AP01SDTM":"2019-02-26 09:05:10","AP01EDTM":"2021-02-25 21:05:10","AP02SDTM":"2021-02-25 21:05:10","AP02EDTM":"2022-02-26 03:05:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-26","EOSDY":1096,"LSTALVDT":"2022-03-17","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2845,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.85008,"AVALU":"U/L","BASE2":19.83643,"BASE":37.23164,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.98636,"PCHG2":-50.34351,"CHG":-27.38156,"PCHG":-73.5438,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-17 09:05:10","ADY":325,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-262","SUBJID":"id-262","SITEID":"CHN-15","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.05546,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-02-26","TRTSDTM":"2019-02-26 09:05:10","TRTEDTM":"2022-02-26 03:05:10","TRT01SDTM":"2019-02-26 09:05:10","TRT01EDTM":"2021-02-25 21:05:10","TRT02SDTM":"2021-02-25 21:05:10","TRT02EDTM":"2022-02-26 03:05:10","AP01SDTM":"2019-02-26 09:05:10","AP01EDTM":"2021-02-25 21:05:10","AP02SDTM":"2021-02-25 21:05:10","AP02EDTM":"2022-02-26 03:05:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-26","EOSDY":1096,"LSTALVDT":"2022-03-17","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":747,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.75461,"AVALU":"U/L","BASE2":19.83643,"BASE":37.23164,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.91817,"PCHG2":49.99978,"CHG":-7.47703,"PCHG":-20.08246,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-21 09:05:10","ADY":450,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-262","SUBJID":"id-262","SITEID":"CHN-15","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.05546,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-02-26","TRTSDTM":"2019-02-26 09:05:10","TRTEDTM":"2022-02-26 03:05:10","TRT01SDTM":"2019-02-26 09:05:10","TRT01EDTM":"2021-02-25 21:05:10","TRT02SDTM":"2021-02-25 21:05:10","TRT02EDTM":"2022-02-26 03:05:10","AP01SDTM":"2019-02-26 09:05:10","AP01EDTM":"2021-02-25 21:05:10","AP02SDTM":"2021-02-25 21:05:10","AP02EDTM":"2022-02-26 03:05:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-26","EOSDY":1096,"LSTALVDT":"2022-03-17","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5703,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.90578,"AVALU":"U/L","BASE2":19.83643,"BASE":37.23164,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.93065,"PCHG2":-65.18638,"CHG":-30.32586,"PCHG":-81.45185,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-07-11 09:05:10","ADY":866,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-262","SUBJID":"id-262","SITEID":"CHN-15","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.05546,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-02-26","TRTSDTM":"2019-02-26 09:05:10","TRTEDTM":"2022-02-26 03:05:10","TRT01SDTM":"2019-02-26 09:05:10","TRT01EDTM":"2021-02-25 21:05:10","TRT02SDTM":"2021-02-25 21:05:10","TRT02EDTM":"2022-02-26 03:05:10","AP01SDTM":"2019-02-26 09:05:10","AP01EDTM":"2021-02-25 21:05:10","AP02SDTM":"2021-02-25 21:05:10","AP02EDTM":"2022-02-26 03:05:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-26","EOSDY":1096,"LSTALVDT":"2022-03-17","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5965,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.50198,"AVALU":"U/L","BASE2":19.83643,"BASE":37.23164,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.66554,"PCHG2":13.43762,"CHG":-14.72966,"PCHG":-39.56221,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-16 09:05:10","ADY":994,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-262","SUBJID":"id-262","SITEID":"CHN-15","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.05546,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-02-26","TRTSDTM":"2019-02-26 09:05:10","TRTEDTM":"2022-02-26 03:05:10","TRT01SDTM":"2019-02-26 09:05:10","TRT01EDTM":"2021-02-25 21:05:10","TRT02SDTM":"2021-02-25 21:05:10","TRT02EDTM":"2022-02-26 03:05:10","AP01SDTM":"2019-02-26 09:05:10","AP01EDTM":"2021-02-25 21:05:10","AP02SDTM":"2021-02-25 21:05:10","AP02EDTM":"2022-02-26 03:05:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-26","EOSDY":1096,"LSTALVDT":"2022-03-17","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4748,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.47384,"AVALU":"mg/L","BASE2":7.47384,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-1","ADTM":"2019-02-28 09:05:10","ADY":2,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-262","SUBJID":"id-262","SITEID":"CHN-15","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.05546,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-02-26","TRTSDTM":"2019-02-26 09:05:10","TRTEDTM":"2022-02-26 03:05:10","TRT01SDTM":"2019-02-26 09:05:10","TRT01EDTM":"2021-02-25 21:05:10","TRT02SDTM":"2021-02-25 21:05:10","TRT02EDTM":"2022-02-26 03:05:10","AP01SDTM":"2019-02-26 09:05:10","AP01EDTM":"2021-02-25 21:05:10","AP02SDTM":"2021-02-25 21:05:10","AP02EDTM":"2022-02-26 03:05:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-26","EOSDY":1096,"LSTALVDT":"2022-03-17","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7256,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.94347,"AVALU":"mg/L","BASE2":7.47384,"BASE":7.94347,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.46963,"PCHG2":6.28368,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2019-06-30 09:05:10","ADY":124,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-262","SUBJID":"id-262","SITEID":"CHN-15","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.05546,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-02-26","TRTSDTM":"2019-02-26 09:05:10","TRTEDTM":"2022-02-26 03:05:10","TRT01SDTM":"2019-02-26 09:05:10","TRT01EDTM":"2021-02-25 21:05:10","TRT02SDTM":"2021-02-25 21:05:10","TRT02EDTM":"2022-02-26 03:05:10","AP01SDTM":"2019-02-26 09:05:10","AP01EDTM":"2021-02-25 21:05:10","AP02SDTM":"2021-02-25 21:05:10","AP02EDTM":"2022-02-26 03:05:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-26","EOSDY":1096,"LSTALVDT":"2022-03-17","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6055,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.58723,"AVALU":"mg/L","BASE2":7.47384,"BASE":7.94347,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11339,"PCHG2":1.51712,"CHG":-0.35624,"PCHG":-4.48475,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-2","BTOXGR":"-1","ADTM":"2019-07-17 09:05:10","ADY":141,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-262","SUBJID":"id-262","SITEID":"CHN-15","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.05546,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-02-26","TRTSDTM":"2019-02-26 09:05:10","TRTEDTM":"2022-02-26 03:05:10","TRT01SDTM":"2019-02-26 09:05:10","TRT01EDTM":"2021-02-25 21:05:10","TRT02SDTM":"2021-02-25 21:05:10","TRT02EDTM":"2022-02-26 03:05:10","AP01SDTM":"2019-02-26 09:05:10","AP01EDTM":"2021-02-25 21:05:10","AP02SDTM":"2021-02-25 21:05:10","AP02EDTM":"2022-02-26 03:05:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-26","EOSDY":1096,"LSTALVDT":"2022-03-17","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7974,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.83689,"AVALU":"mg/L","BASE2":7.47384,"BASE":7.94347,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.36305,"PCHG2":44.99758,"CHG":2.89342,"PCHG":36.42507,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"2","BTOXGR":"-1","ADTM":"2020-01-17 09:05:10","ADY":325,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-262","SUBJID":"id-262","SITEID":"CHN-15","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.05546,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-02-26","TRTSDTM":"2019-02-26 09:05:10","TRTEDTM":"2022-02-26 03:05:10","TRT01SDTM":"2019-02-26 09:05:10","TRT01EDTM":"2021-02-25 21:05:10","TRT02SDTM":"2021-02-25 21:05:10","TRT02EDTM":"2022-02-26 03:05:10","AP01SDTM":"2019-02-26 09:05:10","AP01EDTM":"2021-02-25 21:05:10","AP02SDTM":"2021-02-25 21:05:10","AP02EDTM":"2022-02-26 03:05:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-26","EOSDY":1096,"LSTALVDT":"2022-03-17","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":497,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.20167,"AVALU":"mg/L","BASE2":7.47384,"BASE":7.94347,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.72782,"PCHG2":49.87827,"CHG":3.25819,"PCHG":41.0172,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"3","BTOXGR":"-1","ADTM":"2020-05-21 09:05:10","ADY":450,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-262","SUBJID":"id-262","SITEID":"CHN-15","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.05546,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-02-26","TRTSDTM":"2019-02-26 09:05:10","TRTEDTM":"2022-02-26 03:05:10","TRT01SDTM":"2019-02-26 09:05:10","TRT01EDTM":"2021-02-25 21:05:10","TRT02SDTM":"2021-02-25 21:05:10","TRT02EDTM":"2022-02-26 03:05:10","AP01SDTM":"2019-02-26 09:05:10","AP01EDTM":"2021-02-25 21:05:10","AP02SDTM":"2021-02-25 21:05:10","AP02EDTM":"2022-02-26 03:05:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-26","EOSDY":1096,"LSTALVDT":"2022-03-17","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2348,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.74178,"AVALU":"mg/L","BASE2":7.47384,"BASE":7.94347,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.26793,"PCHG2":16.96494,"CHG":0.7983,"PCHG":10.04977,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-07-11 09:05:10","ADY":866,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-262","SUBJID":"id-262","SITEID":"CHN-15","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.05546,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-02-26","TRTSDTM":"2019-02-26 09:05:10","TRTEDTM":"2022-02-26 03:05:10","TRT01SDTM":"2019-02-26 09:05:10","TRT01EDTM":"2021-02-25 21:05:10","TRT02SDTM":"2021-02-25 21:05:10","TRT02EDTM":"2022-02-26 03:05:10","AP01SDTM":"2019-02-26 09:05:10","AP01EDTM":"2021-02-25 21:05:10","AP02SDTM":"2021-02-25 21:05:10","AP02EDTM":"2022-02-26 03:05:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-26","EOSDY":1096,"LSTALVDT":"2022-03-17","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2387,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.3746,"AVALU":"mg/L","BASE2":7.47384,"BASE":7.94347,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09924,"PCHG2":-1.3278,"CHG":-0.56887,"PCHG":-7.16147,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2021-11-16 09:05:10","ADY":994,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-262","SUBJID":"id-262","SITEID":"CHN-15","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.05546,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-02-26","TRTSDTM":"2019-02-26 09:05:10","TRTEDTM":"2022-02-26 03:05:10","TRT01SDTM":"2019-02-26 09:05:10","TRT01EDTM":"2021-02-25 21:05:10","TRT02SDTM":"2021-02-25 21:05:10","TRT02EDTM":"2022-02-26 03:05:10","AP01SDTM":"2019-02-26 09:05:10","AP01EDTM":"2021-02-25 21:05:10","AP02SDTM":"2021-02-25 21:05:10","AP02EDTM":"2022-02-26 03:05:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-26","EOSDY":1096,"LSTALVDT":"2022-03-17","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6705,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79471,"AVALU":"g/L","BASE2":2.79471,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-02-28 09:05:10","ADY":2,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-262","SUBJID":"id-262","SITEID":"CHN-15","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.05546,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-02-26","TRTSDTM":"2019-02-26 09:05:10","TRTEDTM":"2022-02-26 03:05:10","TRT01SDTM":"2019-02-26 09:05:10","TRT01EDTM":"2021-02-25 21:05:10","TRT02SDTM":"2021-02-25 21:05:10","TRT02EDTM":"2022-02-26 03:05:10","AP01SDTM":"2019-02-26 09:05:10","AP01EDTM":"2021-02-25 21:05:10","AP02SDTM":"2021-02-25 21:05:10","AP02EDTM":"2022-02-26 03:05:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-26","EOSDY":1096,"LSTALVDT":"2022-03-17","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1868,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76546,"AVALU":"g/L","BASE2":2.79471,"BASE":2.76546,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.02925,"PCHG2":-1.0468,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-06-30 09:05:10","ADY":124,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-262","SUBJID":"id-262","SITEID":"CHN-15","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.05546,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-02-26","TRTSDTM":"2019-02-26 09:05:10","TRTEDTM":"2022-02-26 03:05:10","TRT01SDTM":"2019-02-26 09:05:10","TRT01EDTM":"2021-02-25 21:05:10","TRT02SDTM":"2021-02-25 21:05:10","TRT02EDTM":"2022-02-26 03:05:10","AP01SDTM":"2019-02-26 09:05:10","AP01EDTM":"2021-02-25 21:05:10","AP02SDTM":"2021-02-25 21:05:10","AP02EDTM":"2022-02-26 03:05:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-26","EOSDY":1096,"LSTALVDT":"2022-03-17","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7367,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92448,"AVALU":"g/L","BASE2":2.79471,"BASE":2.76546,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12977,"PCHG2":4.64344,"CHG":0.15903,"PCHG":5.75043,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-17 09:05:10","ADY":141,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-262","SUBJID":"id-262","SITEID":"CHN-15","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.05546,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-02-26","TRTSDTM":"2019-02-26 09:05:10","TRTEDTM":"2022-02-26 03:05:10","TRT01SDTM":"2019-02-26 09:05:10","TRT01EDTM":"2021-02-25 21:05:10","TRT02SDTM":"2021-02-25 21:05:10","TRT02EDTM":"2022-02-26 03:05:10","AP01SDTM":"2019-02-26 09:05:10","AP01EDTM":"2021-02-25 21:05:10","AP02SDTM":"2021-02-25 21:05:10","AP02EDTM":"2022-02-26 03:05:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-26","EOSDY":1096,"LSTALVDT":"2022-03-17","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6590,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86094,"AVALU":"g/L","BASE2":2.79471,"BASE":2.76546,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06623,"PCHG2":2.3698,"CHG":0.09548,"PCHG":3.45274,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-17 09:05:10","ADY":325,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-262","SUBJID":"id-262","SITEID":"CHN-15","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.05546,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-02-26","TRTSDTM":"2019-02-26 09:05:10","TRTEDTM":"2022-02-26 03:05:10","TRT01SDTM":"2019-02-26 09:05:10","TRT01EDTM":"2021-02-25 21:05:10","TRT02SDTM":"2021-02-25 21:05:10","TRT02EDTM":"2022-02-26 03:05:10","AP01SDTM":"2019-02-26 09:05:10","AP01EDTM":"2021-02-25 21:05:10","AP02SDTM":"2021-02-25 21:05:10","AP02EDTM":"2022-02-26 03:05:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-26","EOSDY":1096,"LSTALVDT":"2022-03-17","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2106,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89865,"AVALU":"g/L","BASE2":2.79471,"BASE":2.76546,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10394,"PCHG2":3.71921,"CHG":0.1332,"PCHG":4.81643,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-21 09:05:10","ADY":450,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-262","SUBJID":"id-262","SITEID":"CHN-15","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.05546,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-02-26","TRTSDTM":"2019-02-26 09:05:10","TRTEDTM":"2022-02-26 03:05:10","TRT01SDTM":"2019-02-26 09:05:10","TRT01EDTM":"2021-02-25 21:05:10","TRT02SDTM":"2021-02-25 21:05:10","TRT02EDTM":"2022-02-26 03:05:10","AP01SDTM":"2019-02-26 09:05:10","AP01EDTM":"2021-02-25 21:05:10","AP02SDTM":"2021-02-25 21:05:10","AP02EDTM":"2022-02-26 03:05:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-26","EOSDY":1096,"LSTALVDT":"2022-03-17","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4251,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81084,"AVALU":"g/L","BASE2":2.79471,"BASE":2.76546,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01613,"PCHG2":0.57701,"CHG":0.04538,"PCHG":1.64099,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-11 09:05:10","ADY":866,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-262","SUBJID":"id-262","SITEID":"CHN-15","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.05546,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-02-26","TRTSDTM":"2019-02-26 09:05:10","TRTEDTM":"2022-02-26 03:05:10","TRT01SDTM":"2019-02-26 09:05:10","TRT01EDTM":"2021-02-25 21:05:10","TRT02SDTM":"2021-02-25 21:05:10","TRT02EDTM":"2022-02-26 03:05:10","AP01SDTM":"2019-02-26 09:05:10","AP01EDTM":"2021-02-25 21:05:10","AP02SDTM":"2021-02-25 21:05:10","AP02EDTM":"2022-02-26 03:05:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-26","EOSDY":1096,"LSTALVDT":"2022-03-17","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6728,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92055,"AVALU":"g/L","BASE2":2.79471,"BASE":2.76546,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12584,"PCHG2":4.50288,"CHG":0.1551,"PCHG":5.60838,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-16 09:05:10","ADY":994,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-297","SUBJID":"id-297","SITEID":"CHN-15","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.93491,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-20","TRTSDTM":"2019-09-20 10:24:34","TRTEDTM":"2022-02-17 20:34:12","TRT01SDTM":"2019-09-20 10:24:34","TRT01EDTM":"2021-02-17 14:34:12","TRT02SDTM":"2021-02-17 14:34:12","TRT02EDTM":"2022-02-17 20:34:12","AP01SDTM":"2019-09-20 10:24:34","AP01EDTM":"2021-02-17 14:34:12","AP02SDTM":"2021-02-17 14:34:12","AP02EDTM":"2022-02-17 20:34:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":882,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-07","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":27,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.89078,"AVALU":"U/L","BASE2":8.89078,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-06 10:24:34","ADY":77,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-297","SUBJID":"id-297","SITEID":"CHN-15","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.93491,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-20","TRTSDTM":"2019-09-20 10:24:34","TRTEDTM":"2022-02-17 20:34:12","TRT01SDTM":"2019-09-20 10:24:34","TRT01EDTM":"2021-02-17 14:34:12","TRT02SDTM":"2021-02-17 14:34:12","TRT02EDTM":"2022-02-17 20:34:12","AP01SDTM":"2019-09-20 10:24:34","AP01EDTM":"2021-02-17 14:34:12","AP02SDTM":"2021-02-17 14:34:12","AP02EDTM":"2022-02-17 20:34:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":882,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-07","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2520,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.40224,"AVALU":"U/L","BASE2":8.89078,"BASE":8.40224,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.48855,"PCHG2":-5.495,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-08 10:24:34","ADY":79,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-297","SUBJID":"id-297","SITEID":"CHN-15","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.93491,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-20","TRTSDTM":"2019-09-20 10:24:34","TRTEDTM":"2022-02-17 20:34:12","TRT01SDTM":"2019-09-20 10:24:34","TRT01EDTM":"2021-02-17 14:34:12","TRT02SDTM":"2021-02-17 14:34:12","TRT02EDTM":"2022-02-17 20:34:12","AP01SDTM":"2019-09-20 10:24:34","AP01EDTM":"2021-02-17 14:34:12","AP02SDTM":"2021-02-17 14:34:12","AP02EDTM":"2022-02-17 20:34:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":882,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-07","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2429,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.26642,"AVALU":"U/L","BASE2":8.89078,"BASE":8.40224,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.37564,"PCHG2":49.21541,"CHG":4.86418,"PCHG":57.89155,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-16 10:24:34","ADY":118,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-297","SUBJID":"id-297","SITEID":"CHN-15","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.93491,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-20","TRTSDTM":"2019-09-20 10:24:34","TRTEDTM":"2022-02-17 20:34:12","TRT01SDTM":"2019-09-20 10:24:34","TRT01EDTM":"2021-02-17 14:34:12","TRT02SDTM":"2021-02-17 14:34:12","TRT02EDTM":"2022-02-17 20:34:12","AP01SDTM":"2019-09-20 10:24:34","AP01EDTM":"2021-02-17 14:34:12","AP02SDTM":"2021-02-17 14:34:12","AP02EDTM":"2022-02-17 20:34:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":882,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-07","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7523,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.99101,"AVALU":"U/L","BASE2":8.89078,"BASE":8.40224,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.10022,"PCHG2":57.36529,"CHG":5.58877,"PCHG":66.5153,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-19 10:24:34","ADY":181,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-297","SUBJID":"id-297","SITEID":"CHN-15","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.93491,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-20","TRTSDTM":"2019-09-20 10:24:34","TRTEDTM":"2022-02-17 20:34:12","TRT01SDTM":"2019-09-20 10:24:34","TRT01EDTM":"2021-02-17 14:34:12","TRT02SDTM":"2021-02-17 14:34:12","TRT02EDTM":"2022-02-17 20:34:12","AP01SDTM":"2019-09-20 10:24:34","AP01EDTM":"2021-02-17 14:34:12","AP02SDTM":"2021-02-17 14:34:12","AP02EDTM":"2022-02-17 20:34:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":882,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-07","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5516,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.18012,"AVALU":"U/L","BASE2":8.89078,"BASE":8.40224,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.28934,"PCHG2":138.22558,"CHG":12.77789,"PCHG":152.07722,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-16 10:24:34","ADY":331,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-297","SUBJID":"id-297","SITEID":"CHN-15","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.93491,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-20","TRTSDTM":"2019-09-20 10:24:34","TRTEDTM":"2022-02-17 20:34:12","TRT01SDTM":"2019-09-20 10:24:34","TRT01EDTM":"2021-02-17 14:34:12","TRT02SDTM":"2021-02-17 14:34:12","TRT02EDTM":"2022-02-17 20:34:12","AP01SDTM":"2019-09-20 10:24:34","AP01EDTM":"2021-02-17 14:34:12","AP02SDTM":"2021-02-17 14:34:12","AP02EDTM":"2022-02-17 20:34:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":882,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-07","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":858,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.34261,"AVALU":"U/L","BASE2":8.89078,"BASE":8.40224,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.45183,"PCHG2":72.56763,"CHG":6.94038,"PCHG":82.60158,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-28 10:24:34","ADY":343,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-297","SUBJID":"id-297","SITEID":"CHN-15","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.93491,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-20","TRTSDTM":"2019-09-20 10:24:34","TRTEDTM":"2022-02-17 20:34:12","TRT01SDTM":"2019-09-20 10:24:34","TRT01EDTM":"2021-02-17 14:34:12","TRT02SDTM":"2021-02-17 14:34:12","TRT02EDTM":"2022-02-17 20:34:12","AP01SDTM":"2019-09-20 10:24:34","AP01EDTM":"2021-02-17 14:34:12","AP02SDTM":"2021-02-17 14:34:12","AP02EDTM":"2022-02-17 20:34:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":882,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-07","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7303,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.51552,"AVALU":"U/L","BASE2":8.89078,"BASE":8.40224,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.62474,"PCHG2":52.01722,"CHG":5.11329,"PCHG":60.85627,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-12 10:24:34","ADY":419,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-297","SUBJID":"id-297","SITEID":"CHN-15","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.93491,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-20","TRTSDTM":"2019-09-20 10:24:34","TRTEDTM":"2022-02-17 20:34:12","TRT01SDTM":"2019-09-20 10:24:34","TRT01EDTM":"2021-02-17 14:34:12","TRT02SDTM":"2021-02-17 14:34:12","TRT02EDTM":"2022-02-17 20:34:12","AP01SDTM":"2019-09-20 10:24:34","AP01EDTM":"2021-02-17 14:34:12","AP02SDTM":"2021-02-17 14:34:12","AP02EDTM":"2022-02-17 20:34:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":882,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-07","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5286,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.74488,"AVALU":"mg/L","BASE2":8.74488,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-06 10:24:34","ADY":77,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-297","SUBJID":"id-297","SITEID":"CHN-15","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.93491,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-20","TRTSDTM":"2019-09-20 10:24:34","TRTEDTM":"2022-02-17 20:34:12","TRT01SDTM":"2019-09-20 10:24:34","TRT01EDTM":"2021-02-17 14:34:12","TRT02SDTM":"2021-02-17 14:34:12","TRT02EDTM":"2022-02-17 20:34:12","AP01SDTM":"2019-09-20 10:24:34","AP01EDTM":"2021-02-17 14:34:12","AP02SDTM":"2021-02-17 14:34:12","AP02EDTM":"2022-02-17 20:34:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":882,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-07","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8183,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.15259,"AVALU":"mg/L","BASE2":8.74488,"BASE":9.15259,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.40771,"PCHG2":4.66227,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-08 10:24:34","ADY":79,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-297","SUBJID":"id-297","SITEID":"CHN-15","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.93491,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-20","TRTSDTM":"2019-09-20 10:24:34","TRTEDTM":"2022-02-17 20:34:12","TRT01SDTM":"2019-09-20 10:24:34","TRT01EDTM":"2021-02-17 14:34:12","TRT02SDTM":"2021-02-17 14:34:12","TRT02EDTM":"2022-02-17 20:34:12","AP01SDTM":"2019-09-20 10:24:34","AP01EDTM":"2021-02-17 14:34:12","AP02SDTM":"2021-02-17 14:34:12","AP02EDTM":"2022-02-17 20:34:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":882,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-07","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":733,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.72968,"AVALU":"mg/L","BASE2":8.74488,"BASE":9.15259,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.0152,"PCHG2":-11.60908,"CHG":-1.42291,"PCHG":-15.54653,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-01-16 10:24:34","ADY":118,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-297","SUBJID":"id-297","SITEID":"CHN-15","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.93491,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-20","TRTSDTM":"2019-09-20 10:24:34","TRTEDTM":"2022-02-17 20:34:12","TRT01SDTM":"2019-09-20 10:24:34","TRT01EDTM":"2021-02-17 14:34:12","TRT02SDTM":"2021-02-17 14:34:12","TRT02EDTM":"2022-02-17 20:34:12","AP01SDTM":"2019-09-20 10:24:34","AP01EDTM":"2021-02-17 14:34:12","AP02SDTM":"2021-02-17 14:34:12","AP02EDTM":"2022-02-17 20:34:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":882,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-07","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1700,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.35307,"AVALU":"mg/L","BASE2":8.74488,"BASE":9.15259,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.60819,"PCHG2":6.95483,"CHG":0.20048,"PCHG":2.19044,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-19 10:24:34","ADY":181,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-297","SUBJID":"id-297","SITEID":"CHN-15","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.93491,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-20","TRTSDTM":"2019-09-20 10:24:34","TRTEDTM":"2022-02-17 20:34:12","TRT01SDTM":"2019-09-20 10:24:34","TRT01EDTM":"2021-02-17 14:34:12","TRT02SDTM":"2021-02-17 14:34:12","TRT02EDTM":"2022-02-17 20:34:12","AP01SDTM":"2019-09-20 10:24:34","AP01EDTM":"2021-02-17 14:34:12","AP02SDTM":"2021-02-17 14:34:12","AP02EDTM":"2022-02-17 20:34:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":882,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-07","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1321,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.93798,"AVALU":"mg/L","BASE2":8.74488,"BASE":9.15259,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.1931,"PCHG2":25.0787,"CHG":1.78539,"PCHG":19.50696,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-08-16 10:24:34","ADY":331,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-297","SUBJID":"id-297","SITEID":"CHN-15","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.93491,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-20","TRTSDTM":"2019-09-20 10:24:34","TRTEDTM":"2022-02-17 20:34:12","TRT01SDTM":"2019-09-20 10:24:34","TRT01EDTM":"2021-02-17 14:34:12","TRT02SDTM":"2021-02-17 14:34:12","TRT02EDTM":"2022-02-17 20:34:12","AP01SDTM":"2019-09-20 10:24:34","AP01EDTM":"2021-02-17 14:34:12","AP02SDTM":"2021-02-17 14:34:12","AP02EDTM":"2022-02-17 20:34:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":882,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-07","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1917,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.96432,"AVALU":"mg/L","BASE2":8.74488,"BASE":9.15259,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.21945,"PCHG2":2.50944,"CHG":-0.18826,"PCHG":-2.05693,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-28 10:24:34","ADY":343,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-297","SUBJID":"id-297","SITEID":"CHN-15","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.93491,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-20","TRTSDTM":"2019-09-20 10:24:34","TRTEDTM":"2022-02-17 20:34:12","TRT01SDTM":"2019-09-20 10:24:34","TRT01EDTM":"2021-02-17 14:34:12","TRT02SDTM":"2021-02-17 14:34:12","TRT02EDTM":"2022-02-17 20:34:12","AP01SDTM":"2019-09-20 10:24:34","AP01EDTM":"2021-02-17 14:34:12","AP02SDTM":"2021-02-17 14:34:12","AP02EDTM":"2022-02-17 20:34:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":882,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-07","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":57,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.69333,"AVALU":"mg/L","BASE2":8.74488,"BASE":9.15259,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.05154,"PCHG2":-23.45996,"CHG":-2.45925,"PCHG":-26.8695,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-11-12 10:24:34","ADY":419,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-297","SUBJID":"id-297","SITEID":"CHN-15","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.93491,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-20","TRTSDTM":"2019-09-20 10:24:34","TRTEDTM":"2022-02-17 20:34:12","TRT01SDTM":"2019-09-20 10:24:34","TRT01EDTM":"2021-02-17 14:34:12","TRT02SDTM":"2021-02-17 14:34:12","TRT02EDTM":"2022-02-17 20:34:12","AP01SDTM":"2019-09-20 10:24:34","AP01EDTM":"2021-02-17 14:34:12","AP02SDTM":"2021-02-17 14:34:12","AP02EDTM":"2022-02-17 20:34:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":882,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-07","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3839,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80308,"AVALU":"g/L","BASE2":2.80308,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-06 10:24:34","ADY":77,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-297","SUBJID":"id-297","SITEID":"CHN-15","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.93491,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-20","TRTSDTM":"2019-09-20 10:24:34","TRTEDTM":"2022-02-17 20:34:12","TRT01SDTM":"2019-09-20 10:24:34","TRT01EDTM":"2021-02-17 14:34:12","TRT02SDTM":"2021-02-17 14:34:12","TRT02EDTM":"2022-02-17 20:34:12","AP01SDTM":"2019-09-20 10:24:34","AP01EDTM":"2021-02-17 14:34:12","AP02SDTM":"2021-02-17 14:34:12","AP02EDTM":"2022-02-17 20:34:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":882,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-07","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2096,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93966,"AVALU":"g/L","BASE2":2.80308,"BASE":2.93966,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.13658,"PCHG2":4.87246,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-08 10:24:34","ADY":79,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-297","SUBJID":"id-297","SITEID":"CHN-15","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.93491,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-20","TRTSDTM":"2019-09-20 10:24:34","TRTEDTM":"2022-02-17 20:34:12","TRT01SDTM":"2019-09-20 10:24:34","TRT01EDTM":"2021-02-17 14:34:12","TRT02SDTM":"2021-02-17 14:34:12","TRT02EDTM":"2022-02-17 20:34:12","AP01SDTM":"2019-09-20 10:24:34","AP01EDTM":"2021-02-17 14:34:12","AP02SDTM":"2021-02-17 14:34:12","AP02EDTM":"2022-02-17 20:34:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":882,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-07","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4752,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81847,"AVALU":"g/L","BASE2":2.80308,"BASE":2.93966,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01539,"PCHG2":0.5492,"CHG":-0.12118,"PCHG":-4.1224,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-16 10:24:34","ADY":118,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-297","SUBJID":"id-297","SITEID":"CHN-15","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.93491,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-20","TRTSDTM":"2019-09-20 10:24:34","TRTEDTM":"2022-02-17 20:34:12","TRT01SDTM":"2019-09-20 10:24:34","TRT01EDTM":"2021-02-17 14:34:12","TRT02SDTM":"2021-02-17 14:34:12","TRT02EDTM":"2022-02-17 20:34:12","AP01SDTM":"2019-09-20 10:24:34","AP01EDTM":"2021-02-17 14:34:12","AP02SDTM":"2021-02-17 14:34:12","AP02EDTM":"2022-02-17 20:34:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":882,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-07","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4891,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91365,"AVALU":"g/L","BASE2":2.80308,"BASE":2.93966,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11057,"PCHG2":3.94445,"CHG":-0.02601,"PCHG":-0.8849,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-19 10:24:34","ADY":181,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-297","SUBJID":"id-297","SITEID":"CHN-15","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.93491,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-20","TRTSDTM":"2019-09-20 10:24:34","TRTEDTM":"2022-02-17 20:34:12","TRT01SDTM":"2019-09-20 10:24:34","TRT01EDTM":"2021-02-17 14:34:12","TRT02SDTM":"2021-02-17 14:34:12","TRT02EDTM":"2022-02-17 20:34:12","AP01SDTM":"2019-09-20 10:24:34","AP01EDTM":"2021-02-17 14:34:12","AP02SDTM":"2021-02-17 14:34:12","AP02EDTM":"2022-02-17 20:34:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":882,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-07","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3428,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.65051,"AVALU":"g/L","BASE2":2.80308,"BASE":2.93966,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15257,"PCHG2":-5.443,"CHG":-0.28915,"PCHG":-9.8362,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-16 10:24:34","ADY":331,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-297","SUBJID":"id-297","SITEID":"CHN-15","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.93491,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-20","TRTSDTM":"2019-09-20 10:24:34","TRTEDTM":"2022-02-17 20:34:12","TRT01SDTM":"2019-09-20 10:24:34","TRT01EDTM":"2021-02-17 14:34:12","TRT02SDTM":"2021-02-17 14:34:12","TRT02EDTM":"2022-02-17 20:34:12","AP01SDTM":"2019-09-20 10:24:34","AP01EDTM":"2021-02-17 14:34:12","AP02SDTM":"2021-02-17 14:34:12","AP02EDTM":"2022-02-17 20:34:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":882,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-07","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2934,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91305,"AVALU":"g/L","BASE2":2.80308,"BASE":2.93966,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10997,"PCHG2":3.92319,"CHG":-0.02661,"PCHG":-0.90517,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-28 10:24:34","ADY":343,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-297","SUBJID":"id-297","SITEID":"CHN-15","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":11.93491,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-20","TRTSDTM":"2019-09-20 10:24:34","TRTEDTM":"2022-02-17 20:34:12","TRT01SDTM":"2019-09-20 10:24:34","TRT01EDTM":"2021-02-17 14:34:12","TRT02SDTM":"2021-02-17 14:34:12","TRT02EDTM":"2022-02-17 20:34:12","AP01SDTM":"2019-09-20 10:24:34","AP01EDTM":"2021-02-17 14:34:12","AP02SDTM":"2021-02-17 14:34:12","AP02EDTM":"2022-02-17 20:34:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":882,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-07","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4624,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82652,"AVALU":"g/L","BASE2":2.80308,"BASE":2.93966,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02344,"PCHG2":0.83612,"CHG":-0.11314,"PCHG":-3.84881,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-12 10:24:34","ADY":419,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-399","SUBJID":"id-399","SITEID":"CHN-15","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":0.99183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-15 09:24:21","TRT01SDTM":"2019-10-15 09:24:21","AP01SDTM":"2019-10-15 09:24:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4441,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.20443,"AVALU":"U/L","BASE2":16.20443,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-06-09 09:24:21","ADY":238,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-399","SUBJID":"id-399","SITEID":"CHN-15","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":0.99183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-15 09:24:21","TRT01SDTM":"2019-10-15 09:24:21","AP01SDTM":"2019-10-15 09:24:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4988,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.54187,"AVALU":"U/L","BASE2":16.20443,"BASE":4.54187,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-11.66256,"PCHG2":-71.97143,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2020-08-20 09:24:21","ADY":310,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-399","SUBJID":"id-399","SITEID":"CHN-15","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":0.99183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-15 09:24:21","TRT01SDTM":"2019-10-15 09:24:21","AP01SDTM":"2019-10-15 09:24:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5942,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.21877,"AVALU":"U/L","BASE2":16.20443,"BASE":4.54187,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.01434,"PCHG2":18.60194,"CHG":14.6769,"PCHG":323.14663,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-01-27 09:24:21","ADY":470,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-399","SUBJID":"id-399","SITEID":"CHN-15","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":0.99183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-15 09:24:21","TRT01SDTM":"2019-10-15 09:24:21","AP01SDTM":"2019-10-15 09:24:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7112,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.51704,"AVALU":"U/L","BASE2":16.20443,"BASE":4.54187,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.68739,"PCHG2":-16.58429,"CHG":8.97517,"PCHG":197.60961,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-03-28 09:24:21","ADY":530,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-399","SUBJID":"id-399","SITEID":"CHN-15","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":0.99183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-15 09:24:21","TRT01SDTM":"2019-10-15 09:24:21","AP01SDTM":"2019-10-15 09:24:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6614,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.23218,"AVALU":"U/L","BASE2":16.20443,"BASE":4.54187,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.97225,"PCHG2":-86.22486,"CHG":-2.30969,"PCHG":-50.85322,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2021-04-07 09:24:21","ADY":540,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-399","SUBJID":"id-399","SITEID":"CHN-15","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":0.99183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-15 09:24:21","TRT01SDTM":"2019-10-15 09:24:21","AP01SDTM":"2019-10-15 09:24:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6438,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.52842,"AVALU":"U/L","BASE2":16.20443,"BASE":4.54187,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.32399,"PCHG2":14.34166,"CHG":13.98655,"PCHG":307.94686,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-08-01 09:24:21","ADY":656,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-399","SUBJID":"id-399","SITEID":"CHN-15","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":0.99183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-15 09:24:21","TRT01SDTM":"2019-10-15 09:24:21","AP01SDTM":"2019-10-15 09:24:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2531,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.56013,"AVALU":"U/L","BASE2":16.20443,"BASE":4.54187,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.64431,"PCHG2":-3.97611,"CHG":11.01826,"PCHG":242.59293,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-10-09 09:24:21","ADY":725,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-399","SUBJID":"id-399","SITEID":"CHN-15","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":0.99183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-15 09:24:21","TRT01SDTM":"2019-10-15 09:24:21","AP01SDTM":"2019-10-15 09:24:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2169,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.74885,"AVALU":"mg/L","BASE2":9.74885,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-09 09:24:21","ADY":238,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-399","SUBJID":"id-399","SITEID":"CHN-15","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":0.99183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-15 09:24:21","TRT01SDTM":"2019-10-15 09:24:21","AP01SDTM":"2019-10-15 09:24:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2179,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.93533,"AVALU":"mg/L","BASE2":9.74885,"BASE":9.93533,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.18649,"PCHG2":1.91291,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-20 09:24:21","ADY":310,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-399","SUBJID":"id-399","SITEID":"CHN-15","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":0.99183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-15 09:24:21","TRT01SDTM":"2019-10-15 09:24:21","AP01SDTM":"2019-10-15 09:24:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2327,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.25166,"AVALU":"mg/L","BASE2":9.74885,"BASE":9.93533,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.50281,"PCHG2":15.41529,"CHG":1.31633,"PCHG":13.24894,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-01-27 09:24:21","ADY":470,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-399","SUBJID":"id-399","SITEID":"CHN-15","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":0.99183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-15 09:24:21","TRT01SDTM":"2019-10-15 09:24:21","AP01SDTM":"2019-10-15 09:24:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":852,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.67537,"AVALU":"mg/L","BASE2":9.74885,"BASE":9.93533,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.07348,"PCHG2":-11.01136,"CHG":-1.25997,"PCHG":-12.68168,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-28 09:24:21","ADY":530,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-399","SUBJID":"id-399","SITEID":"CHN-15","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":0.99183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-15 09:24:21","TRT01SDTM":"2019-10-15 09:24:21","AP01SDTM":"2019-10-15 09:24:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":298,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.71779,"AVALU":"mg/L","BASE2":9.74885,"BASE":9.93533,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03106,"PCHG2":-0.31863,"CHG":-0.21755,"PCHG":-2.18965,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-07 09:24:21","ADY":540,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-399","SUBJID":"id-399","SITEID":"CHN-15","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":0.99183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-15 09:24:21","TRT01SDTM":"2019-10-15 09:24:21","AP01SDTM":"2019-10-15 09:24:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4579,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.44883,"AVALU":"mg/L","BASE2":9.74885,"BASE":9.93533,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.30002,"PCHG2":-23.59275,"CHG":-2.48651,"PCHG":-25.02692,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-08-01 09:24:21","ADY":656,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-399","SUBJID":"id-399","SITEID":"CHN-15","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":0.99183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-15 09:24:21","TRT01SDTM":"2019-10-15 09:24:21","AP01SDTM":"2019-10-15 09:24:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5038,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.42788,"AVALU":"mg/L","BASE2":9.74885,"BASE":9.93533,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.32097,"PCHG2":-23.80764,"CHG":-2.50746,"PCHG":-25.23777,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-10-09 09:24:21","ADY":725,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-399","SUBJID":"id-399","SITEID":"CHN-15","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":0.99183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-15 09:24:21","TRT01SDTM":"2019-10-15 09:24:21","AP01SDTM":"2019-10-15 09:24:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3716,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93343,"AVALU":"g/L","BASE2":2.93343,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-09 09:24:21","ADY":238,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-399","SUBJID":"id-399","SITEID":"CHN-15","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":0.99183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-15 09:24:21","TRT01SDTM":"2019-10-15 09:24:21","AP01SDTM":"2019-10-15 09:24:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2551,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83911,"AVALU":"g/L","BASE2":2.93343,"BASE":2.83911,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.09433,"PCHG2":-3.21555,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-20 09:24:21","ADY":310,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-399","SUBJID":"id-399","SITEID":"CHN-15","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":0.99183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-15 09:24:21","TRT01SDTM":"2019-10-15 09:24:21","AP01SDTM":"2019-10-15 09:24:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5722,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94542,"AVALU":"g/L","BASE2":2.93343,"BASE":2.83911,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01199,"PCHG2":0.40858,"CHG":0.10631,"PCHG":3.74453,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-27 09:24:21","ADY":470,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-399","SUBJID":"id-399","SITEID":"CHN-15","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":0.99183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-15 09:24:21","TRT01SDTM":"2019-10-15 09:24:21","AP01SDTM":"2019-10-15 09:24:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2183,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92343,"AVALU":"g/L","BASE2":2.93343,"BASE":2.83911,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01001,"PCHG2":-0.34108,"CHG":0.08432,"PCHG":2.96997,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-28 09:24:21","ADY":530,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-399","SUBJID":"id-399","SITEID":"CHN-15","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":0.99183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-15 09:24:21","TRT01SDTM":"2019-10-15 09:24:21","AP01SDTM":"2019-10-15 09:24:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":485,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.70905,"AVALU":"g/L","BASE2":2.93343,"BASE":2.83911,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.22438,"PCHG2":-7.64911,"CHG":-0.13006,"PCHG":-4.58086,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-07 09:24:21","ADY":540,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-399","SUBJID":"id-399","SITEID":"CHN-15","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":0.99183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-15 09:24:21","TRT01SDTM":"2019-10-15 09:24:21","AP01SDTM":"2019-10-15 09:24:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5507,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79153,"AVALU":"g/L","BASE2":2.93343,"BASE":2.83911,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1419,"PCHG2":-4.83736,"CHG":-0.04757,"PCHG":-1.6757,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-01 09:24:21","ADY":656,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-15-id-399","SUBJID":"id-399","SITEID":"CHN-15","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-15","INVNAM":"Dr. CHN-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":0.99183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-13","TRTSDTM":"2019-10-15 09:24:21","TRT01SDTM":"2019-10-15 09:24:21","AP01SDTM":"2019-10-15 09:24:21","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1574,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87706,"AVALU":"g/L","BASE2":2.93343,"BASE":2.83911,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05638,"PCHG2":-1.92183,"CHG":0.03795,"PCHG":1.3367,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-09 09:24:21","ADY":725,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-154","SUBJID":"id-154","SITEID":"CHN-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.17155,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-12","TRTSDTM":"2019-12-15 09:30:03","TRT01SDTM":"2019-12-15 09:30:03","AP01SDTM":"2019-12-15 09:30:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":924,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.70638,"AVALU":"U/L","BASE2":8.70638,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-09 09:30:03","ADY":146,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-154","SUBJID":"id-154","SITEID":"CHN-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.17155,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-12","TRTSDTM":"2019-12-15 09:30:03","TRT01SDTM":"2019-12-15 09:30:03","AP01SDTM":"2019-12-15 09:30:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7517,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.14396,"AVALU":"U/L","BASE2":8.70638,"BASE":24.14396,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":15.43758,"PCHG2":177.31347,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-14 09:30:03","ADY":151,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-154","SUBJID":"id-154","SITEID":"CHN-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.17155,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-12","TRTSDTM":"2019-12-15 09:30:03","TRT01SDTM":"2019-12-15 09:30:03","AP01SDTM":"2019-12-15 09:30:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5328,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.41078,"AVALU":"U/L","BASE2":8.70638,"BASE":24.14396,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.7044,"PCHG2":168.89227,"CHG":-0.73318,"PCHG":-3.03671,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-16 09:30:03","ADY":245,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-154","SUBJID":"id-154","SITEID":"CHN-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.17155,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-12","TRTSDTM":"2019-12-15 09:30:03","TRT01SDTM":"2019-12-15 09:30:03","AP01SDTM":"2019-12-15 09:30:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1821,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.99117,"AVALU":"U/L","BASE2":8.70638,"BASE":24.14396,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":25.28479,"PCHG2":290.41687,"CHG":9.84721,"PCHG":40.7854,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-10 09:30:03","ADY":300,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-154","SUBJID":"id-154","SITEID":"CHN-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.17155,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-12","TRTSDTM":"2019-12-15 09:30:03","TRT01SDTM":"2019-12-15 09:30:03","AP01SDTM":"2019-12-15 09:30:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1079,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.58721,"AVALU":"U/L","BASE2":8.70638,"BASE":24.14396,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.11917,"PCHG2":-47.31207,"CHG":-19.55675,"PCHG":-81.00059,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-11-05 09:30:03","ADY":326,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-154","SUBJID":"id-154","SITEID":"CHN-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.17155,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-12","TRTSDTM":"2019-12-15 09:30:03","TRT01SDTM":"2019-12-15 09:30:03","AP01SDTM":"2019-12-15 09:30:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5274,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.83773,"AVALU":"U/L","BASE2":8.70638,"BASE":24.14396,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.86865,"PCHG2":-9.97719,"CHG":-16.30623,"PCHG":-67.53753,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-29 09:30:03","ADY":380,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-154","SUBJID":"id-154","SITEID":"CHN-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.17155,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-12","TRTSDTM":"2019-12-15 09:30:03","TRT01SDTM":"2019-12-15 09:30:03","AP01SDTM":"2019-12-15 09:30:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":429,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.42885,"AVALU":"U/L","BASE2":8.70638,"BASE":24.14396,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.72247,"PCHG2":42.75567,"CHG":-11.71511,"PCHG":-48.52191,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-20 09:30:03","ADY":433,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-154","SUBJID":"id-154","SITEID":"CHN-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.17155,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-12","TRTSDTM":"2019-12-15 09:30:03","TRT01SDTM":"2019-12-15 09:30:03","AP01SDTM":"2019-12-15 09:30:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":305,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.77344,"AVALU":"mg/L","BASE2":8.77344,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-09 09:30:03","ADY":146,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-154","SUBJID":"id-154","SITEID":"CHN-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.17155,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-12","TRTSDTM":"2019-12-15 09:30:03","TRT01SDTM":"2019-12-15 09:30:03","AP01SDTM":"2019-12-15 09:30:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":618,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.73646,"AVALU":"mg/L","BASE2":8.77344,"BASE":9.73646,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.96302,"PCHG2":10.97653,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-14 09:30:03","ADY":151,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-154","SUBJID":"id-154","SITEID":"CHN-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.17155,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-12","TRTSDTM":"2019-12-15 09:30:03","TRT01SDTM":"2019-12-15 09:30:03","AP01SDTM":"2019-12-15 09:30:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5975,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.05349,"AVALU":"mg/L","BASE2":8.77344,"BASE":9.73646,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.71995,"PCHG2":-8.20607,"CHG":-1.68297,"PCHG":-17.28528,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-16 09:30:03","ADY":245,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-154","SUBJID":"id-154","SITEID":"CHN-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.17155,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-12","TRTSDTM":"2019-12-15 09:30:03","TRT01SDTM":"2019-12-15 09:30:03","AP01SDTM":"2019-12-15 09:30:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6882,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.88296,"AVALU":"mg/L","BASE2":8.77344,"BASE":9.73646,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.10952,"PCHG2":12.64633,"CHG":0.1465,"PCHG":1.50464,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-10 09:30:03","ADY":300,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-154","SUBJID":"id-154","SITEID":"CHN-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.17155,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-12","TRTSDTM":"2019-12-15 09:30:03","TRT01SDTM":"2019-12-15 09:30:03","AP01SDTM":"2019-12-15 09:30:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5727,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.51034,"AVALU":"mg/L","BASE2":8.77344,"BASE":9.73646,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.2631,"PCHG2":-2.99879,"CHG":-1.22612,"PCHG":-12.59304,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-05 09:30:03","ADY":326,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-154","SUBJID":"id-154","SITEID":"CHN-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.17155,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-12","TRTSDTM":"2019-12-15 09:30:03","TRT01SDTM":"2019-12-15 09:30:03","AP01SDTM":"2019-12-15 09:30:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6311,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.76093,"AVALU":"mg/L","BASE2":8.77344,"BASE":9.73646,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.98749,"PCHG2":11.25547,"CHG":0.02447,"PCHG":0.25135,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-29 09:30:03","ADY":380,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-154","SUBJID":"id-154","SITEID":"CHN-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.17155,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-12","TRTSDTM":"2019-12-15 09:30:03","TRT01SDTM":"2019-12-15 09:30:03","AP01SDTM":"2019-12-15 09:30:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6191,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.91682,"AVALU":"mg/L","BASE2":8.77344,"BASE":9.73646,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.85662,"PCHG2":-9.76382,"CHG":-1.81964,"PCHG":-18.68895,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-02-20 09:30:03","ADY":433,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-154","SUBJID":"id-154","SITEID":"CHN-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.17155,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-12","TRTSDTM":"2019-12-15 09:30:03","TRT01SDTM":"2019-12-15 09:30:03","AP01SDTM":"2019-12-15 09:30:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2676,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93617,"AVALU":"g/L","BASE2":2.93617,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-09 09:30:03","ADY":146,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-154","SUBJID":"id-154","SITEID":"CHN-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.17155,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-12","TRTSDTM":"2019-12-15 09:30:03","TRT01SDTM":"2019-12-15 09:30:03","AP01SDTM":"2019-12-15 09:30:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6805,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92366,"AVALU":"g/L","BASE2":2.93617,"BASE":2.92366,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.01251,"PCHG2":-0.42602,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-14 09:30:03","ADY":151,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-154","SUBJID":"id-154","SITEID":"CHN-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.17155,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-12","TRTSDTM":"2019-12-15 09:30:03","TRT01SDTM":"2019-12-15 09:30:03","AP01SDTM":"2019-12-15 09:30:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1221,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96002,"AVALU":"g/L","BASE2":2.93617,"BASE":2.92366,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02385,"PCHG2":0.81222,"CHG":0.03636,"PCHG":1.24354,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-16 09:30:03","ADY":245,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-154","SUBJID":"id-154","SITEID":"CHN-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.17155,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-12","TRTSDTM":"2019-12-15 09:30:03","TRT01SDTM":"2019-12-15 09:30:03","AP01SDTM":"2019-12-15 09:30:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4243,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93506,"AVALU":"g/L","BASE2":2.93617,"BASE":2.92366,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00111,"PCHG2":-0.03773,"CHG":0.0114,"PCHG":0.38995,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-10 09:30:03","ADY":300,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-154","SUBJID":"id-154","SITEID":"CHN-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.17155,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-12","TRTSDTM":"2019-12-15 09:30:03","TRT01SDTM":"2019-12-15 09:30:03","AP01SDTM":"2019-12-15 09:30:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":133,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89822,"AVALU":"g/L","BASE2":2.93617,"BASE":2.92366,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03795,"PCHG2":-1.29245,"CHG":-0.02544,"PCHG":-0.87013,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-05 09:30:03","ADY":326,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-154","SUBJID":"id-154","SITEID":"CHN-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.17155,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-12","TRTSDTM":"2019-12-15 09:30:03","TRT01SDTM":"2019-12-15 09:30:03","AP01SDTM":"2019-12-15 09:30:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4130,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.73027,"AVALU":"g/L","BASE2":2.93617,"BASE":2.92366,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.2059,"PCHG2":-7.01249,"CHG":-0.19339,"PCHG":-6.61465,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-29 09:30:03","ADY":380,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-154","SUBJID":"id-154","SITEID":"CHN-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.17155,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-12","TRTSDTM":"2019-12-15 09:30:03","TRT01SDTM":"2019-12-15 09:30:03","AP01SDTM":"2019-12-15 09:30:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4439,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84494,"AVALU":"g/L","BASE2":2.93617,"BASE":2.92366,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09123,"PCHG2":-3.10721,"CHG":-0.07872,"PCHG":-2.69266,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-20 09:30:03","ADY":433,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-241","SUBJID":"id-241","SITEID":"CHN-16","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.53579,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-16","TRTSDTM":"2019-11-19 07:12:54","TRT01SDTM":"2019-11-19 07:12:54","AP01SDTM":"2019-11-19 07:12:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6499,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.35028,"AVALU":"U/L","BASE2":1.35028,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2019-12-15 07:12:54","ADY":26,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-241","SUBJID":"id-241","SITEID":"CHN-16","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.53579,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-16","TRTSDTM":"2019-11-19 07:12:54","TRT01SDTM":"2019-11-19 07:12:54","AP01SDTM":"2019-11-19 07:12:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4318,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.44354,"AVALU":"U/L","BASE2":1.35028,"BASE":12.44354,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":11.09326,"PCHG2":821.55547,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-08 07:12:54","ADY":202,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-241","SUBJID":"id-241","SITEID":"CHN-16","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.53579,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-16","TRTSDTM":"2019-11-19 07:12:54","TRT01SDTM":"2019-11-19 07:12:54","AP01SDTM":"2019-11-19 07:12:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2063,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.93595,"AVALU":"U/L","BASE2":1.35028,"BASE":12.44354,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.58568,"PCHG2":858.02302,"CHG":0.49241,"PCHG":3.95717,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-30 07:12:54","ADY":377,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-241","SUBJID":"id-241","SITEID":"CHN-16","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.53579,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-16","TRTSDTM":"2019-11-19 07:12:54","TRT01SDTM":"2019-11-19 07:12:54","AP01SDTM":"2019-11-19 07:12:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1994,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.24419,"AVALU":"U/L","BASE2":1.35028,"BASE":12.44354,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":26.89391,"PCHG2":1991.73491,"CHG":15.80065,"PCHG":126.97873,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-11 07:12:54","ADY":600,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-241","SUBJID":"id-241","SITEID":"CHN-16","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.53579,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-16","TRTSDTM":"2019-11-19 07:12:54","TRT01SDTM":"2019-11-19 07:12:54","AP01SDTM":"2019-11-19 07:12:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1874,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.77841,"AVALU":"U/L","BASE2":1.35028,"BASE":12.44354,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":20.42814,"PCHG2":1512.88651,"CHG":9.33487,"PCHG":75.01784,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-28 07:12:54","ADY":617,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-241","SUBJID":"id-241","SITEID":"CHN-16","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.53579,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-16","TRTSDTM":"2019-11-19 07:12:54","TRT01SDTM":"2019-11-19 07:12:54","AP01SDTM":"2019-11-19 07:12:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1486,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.45073,"AVALU":"U/L","BASE2":1.35028,"BASE":12.44354,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":23.10045,"PCHG2":1710.79549,"CHG":12.00719,"PCHG":96.49338,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-30 07:12:54","ADY":650,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-241","SUBJID":"id-241","SITEID":"CHN-16","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.53579,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-16","TRTSDTM":"2019-11-19 07:12:54","TRT01SDTM":"2019-11-19 07:12:54","AP01SDTM":"2019-11-19 07:12:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6462,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.93109,"AVALU":"U/L","BASE2":1.35028,"BASE":12.44354,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":22.58081,"PCHG2":1672.31114,"CHG":11.48755,"PCHG":92.31736,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-22 07:12:54","ADY":703,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-241","SUBJID":"id-241","SITEID":"CHN-16","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.53579,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-16","TRTSDTM":"2019-11-19 07:12:54","TRT01SDTM":"2019-11-19 07:12:54","AP01SDTM":"2019-11-19 07:12:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6803,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.32709,"AVALU":"mg/L","BASE2":7.32709,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2019-12-15 07:12:54","ADY":26,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-241","SUBJID":"id-241","SITEID":"CHN-16","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.53579,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-16","TRTSDTM":"2019-11-19 07:12:54","TRT01SDTM":"2019-11-19 07:12:54","AP01SDTM":"2019-11-19 07:12:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":567,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.82161,"AVALU":"mg/L","BASE2":7.32709,"BASE":9.82161,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.49451,"PCHG2":34.04503,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-08 07:12:54","ADY":202,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-241","SUBJID":"id-241","SITEID":"CHN-16","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.53579,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-16","TRTSDTM":"2019-11-19 07:12:54","TRT01SDTM":"2019-11-19 07:12:54","AP01SDTM":"2019-11-19 07:12:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7342,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.36356,"AVALU":"mg/L","BASE2":7.32709,"BASE":9.82161,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.03647,"PCHG2":27.79369,"CHG":-0.45804,"PCHG":-4.66362,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-30 07:12:54","ADY":377,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-241","SUBJID":"id-241","SITEID":"CHN-16","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.53579,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-16","TRTSDTM":"2019-11-19 07:12:54","TRT01SDTM":"2019-11-19 07:12:54","AP01SDTM":"2019-11-19 07:12:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2859,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.33794,"AVALU":"mg/L","BASE2":7.32709,"BASE":9.82161,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.01084,"PCHG2":41.09193,"CHG":0.51633,"PCHG":5.25711,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-07-11 07:12:54","ADY":600,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-241","SUBJID":"id-241","SITEID":"CHN-16","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.53579,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-16","TRTSDTM":"2019-11-19 07:12:54","TRT01SDTM":"2019-11-19 07:12:54","AP01SDTM":"2019-11-19 07:12:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4788,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.81855,"AVALU":"mg/L","BASE2":7.32709,"BASE":9.82161,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.49145,"PCHG2":20.35529,"CHG":-1.00306,"PCHG":-10.21279,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-28 07:12:54","ADY":617,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-241","SUBJID":"id-241","SITEID":"CHN-16","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.53579,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-16","TRTSDTM":"2019-11-19 07:12:54","TRT01SDTM":"2019-11-19 07:12:54","AP01SDTM":"2019-11-19 07:12:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3213,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.55682,"AVALU":"mg/L","BASE2":7.32709,"BASE":9.82161,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.22972,"PCHG2":30.43118,"CHG":-0.26479,"PCHG":-2.696,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-30 07:12:54","ADY":650,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-241","SUBJID":"id-241","SITEID":"CHN-16","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.53579,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-16","TRTSDTM":"2019-11-19 07:12:54","TRT01SDTM":"2019-11-19 07:12:54","AP01SDTM":"2019-11-19 07:12:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5348,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.67369,"AVALU":"mg/L","BASE2":7.32709,"BASE":9.82161,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.34659,"PCHG2":32.02625,"CHG":-0.14792,"PCHG":-1.50605,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-22 07:12:54","ADY":703,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-241","SUBJID":"id-241","SITEID":"CHN-16","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.53579,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-16","TRTSDTM":"2019-11-19 07:12:54","TRT01SDTM":"2019-11-19 07:12:54","AP01SDTM":"2019-11-19 07:12:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4475,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84495,"AVALU":"g/L","BASE2":2.84495,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-15 07:12:54","ADY":26,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-241","SUBJID":"id-241","SITEID":"CHN-16","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.53579,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-16","TRTSDTM":"2019-11-19 07:12:54","TRT01SDTM":"2019-11-19 07:12:54","AP01SDTM":"2019-11-19 07:12:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7012,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98307,"AVALU":"g/L","BASE2":2.84495,"BASE":2.98307,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.13812,"PCHG2":4.85504,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-08 07:12:54","ADY":202,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-241","SUBJID":"id-241","SITEID":"CHN-16","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.53579,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-16","TRTSDTM":"2019-11-19 07:12:54","TRT01SDTM":"2019-11-19 07:12:54","AP01SDTM":"2019-11-19 07:12:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7285,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88896,"AVALU":"g/L","BASE2":2.84495,"BASE":2.98307,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04401,"PCHG2":1.54699,"CHG":-0.09411,"PCHG":-3.15488,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-30 07:12:54","ADY":377,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-241","SUBJID":"id-241","SITEID":"CHN-16","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.53579,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-16","TRTSDTM":"2019-11-19 07:12:54","TRT01SDTM":"2019-11-19 07:12:54","AP01SDTM":"2019-11-19 07:12:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7354,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95323,"AVALU":"g/L","BASE2":2.84495,"BASE":2.98307,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10829,"PCHG2":3.80632,"CHG":-0.02984,"PCHG":-1.00016,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-11 07:12:54","ADY":600,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-241","SUBJID":"id-241","SITEID":"CHN-16","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.53579,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-16","TRTSDTM":"2019-11-19 07:12:54","TRT01SDTM":"2019-11-19 07:12:54","AP01SDTM":"2019-11-19 07:12:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":354,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90476,"AVALU":"g/L","BASE2":2.84495,"BASE":2.98307,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05981,"PCHG2":2.10234,"CHG":-0.07831,"PCHG":-2.62524,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-28 07:12:54","ADY":617,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-241","SUBJID":"id-241","SITEID":"CHN-16","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.53579,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-16","TRTSDTM":"2019-11-19 07:12:54","TRT01SDTM":"2019-11-19 07:12:54","AP01SDTM":"2019-11-19 07:12:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7313,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92902,"AVALU":"g/L","BASE2":2.84495,"BASE":2.98307,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08408,"PCHG2":2.95538,"CHG":-0.05404,"PCHG":-1.8117,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-30 07:12:54","ADY":650,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-241","SUBJID":"id-241","SITEID":"CHN-16","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.53579,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-16","TRTSDTM":"2019-11-19 07:12:54","TRT01SDTM":"2019-11-19 07:12:54","AP01SDTM":"2019-11-19 07:12:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":196,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96461,"AVALU":"g/L","BASE2":2.84495,"BASE":2.98307,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11967,"PCHG2":4.20632,"CHG":-0.01846,"PCHG":-0.61869,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-22 07:12:54","ADY":703,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-302","SUBJID":"id-302","SITEID":"CHN-16","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.79834,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-06","TRTSDTM":"2020-11-09 15:41:39","TRTEDTM":"2022-02-12 23:22:15","TRT01SDTM":"2020-11-09 15:41:39","TRT01EDTM":"2021-02-12 17:22:15","TRT02SDTM":"2021-02-12 17:22:15","TRT02EDTM":"2022-02-12 23:22:15","AP01SDTM":"2020-11-09 15:41:39","AP01EDTM":"2021-02-12 17:22:15","AP02SDTM":"2021-02-12 17:22:15","AP02EDTM":"2022-02-12 23:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":461,"DCSREAS":"DEATH","DTHDT":"2022-03-15","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-15","DTHADY":490,"ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3059,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.10501,"AVALU":"U/L","BASE2":15.10501,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-4","ADTM":"2020-11-21 15:41:39","ADY":12,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-302","SUBJID":"id-302","SITEID":"CHN-16","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.79834,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-06","TRTSDTM":"2020-11-09 15:41:39","TRTEDTM":"2022-02-12 23:22:15","TRT01SDTM":"2020-11-09 15:41:39","TRT01EDTM":"2021-02-12 17:22:15","TRT02SDTM":"2021-02-12 17:22:15","TRT02EDTM":"2022-02-12 23:22:15","AP01SDTM":"2020-11-09 15:41:39","AP01EDTM":"2021-02-12 17:22:15","AP02SDTM":"2021-02-12 17:22:15","AP02EDTM":"2022-02-12 23:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":461,"DCSREAS":"DEATH","DTHDT":"2022-03-15","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-15","DTHADY":490,"ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7577,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.80101,"AVALU":"U/L","BASE2":15.10501,"BASE":3.80101,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-11.304,"PCHG2":-74.83609,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-4","BTOXGR":"-4","ADTM":"2020-12-19 15:41:39","ADY":40,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-302","SUBJID":"id-302","SITEID":"CHN-16","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.79834,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-06","TRTSDTM":"2020-11-09 15:41:39","TRTEDTM":"2022-02-12 23:22:15","TRT01SDTM":"2020-11-09 15:41:39","TRT01EDTM":"2021-02-12 17:22:15","TRT02SDTM":"2021-02-12 17:22:15","TRT02EDTM":"2022-02-12 23:22:15","AP01SDTM":"2020-11-09 15:41:39","AP01EDTM":"2021-02-12 17:22:15","AP02SDTM":"2021-02-12 17:22:15","AP02EDTM":"2022-02-12 23:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":461,"DCSREAS":"DEATH","DTHDT":"2022-03-15","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-15","DTHADY":490,"ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5661,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.2833,"AVALU":"U/L","BASE2":15.10501,"BASE":3.80101,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.82171,"PCHG2":-18.6806,"CHG":8.48229,"PCHG":223.15881,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2020-12-31 15:41:39","ADY":52,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-302","SUBJID":"id-302","SITEID":"CHN-16","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.79834,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-06","TRTSDTM":"2020-11-09 15:41:39","TRTEDTM":"2022-02-12 23:22:15","TRT01SDTM":"2020-11-09 15:41:39","TRT01EDTM":"2021-02-12 17:22:15","TRT02SDTM":"2021-02-12 17:22:15","TRT02EDTM":"2022-02-12 23:22:15","AP01SDTM":"2020-11-09 15:41:39","AP01EDTM":"2021-02-12 17:22:15","AP02SDTM":"2021-02-12 17:22:15","AP02EDTM":"2022-02-12 23:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":461,"DCSREAS":"DEATH","DTHDT":"2022-03-15","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-15","DTHADY":490,"ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1353,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.5868,"AVALU":"U/L","BASE2":15.10501,"BASE":3.80101,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.4818,"PCHG2":122.35545,"CHG":29.78579,"PCHG":783.62833,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-01-21 15:41:39","ADY":73,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-302","SUBJID":"id-302","SITEID":"CHN-16","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.79834,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-06","TRTSDTM":"2020-11-09 15:41:39","TRTEDTM":"2022-02-12 23:22:15","TRT01SDTM":"2020-11-09 15:41:39","TRT01EDTM":"2021-02-12 17:22:15","TRT02SDTM":"2021-02-12 17:22:15","TRT02EDTM":"2022-02-12 23:22:15","AP01SDTM":"2020-11-09 15:41:39","AP01EDTM":"2021-02-12 17:22:15","AP02SDTM":"2021-02-12 17:22:15","AP02EDTM":"2022-02-12 23:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":461,"DCSREAS":"DEATH","DTHDT":"2022-03-15","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-15","DTHADY":490,"ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5651,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.78924,"AVALU":"U/L","BASE2":15.10501,"BASE":3.80101,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.31577,"PCHG2":-74.91402,"CHG":-0.01177,"PCHG":-0.30969,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-4","ADTM":"2021-04-19 15:41:39","ADY":161,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-302","SUBJID":"id-302","SITEID":"CHN-16","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.79834,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-06","TRTSDTM":"2020-11-09 15:41:39","TRTEDTM":"2022-02-12 23:22:15","TRT01SDTM":"2020-11-09 15:41:39","TRT01EDTM":"2021-02-12 17:22:15","TRT02SDTM":"2021-02-12 17:22:15","TRT02EDTM":"2022-02-12 23:22:15","AP01SDTM":"2020-11-09 15:41:39","AP01EDTM":"2021-02-12 17:22:15","AP02SDTM":"2021-02-12 17:22:15","AP02EDTM":"2022-02-12 23:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":461,"DCSREAS":"DEATH","DTHDT":"2022-03-15","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-15","DTHADY":490,"ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7328,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.47352,"AVALU":"U/L","BASE2":15.10501,"BASE":3.80101,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.36851,"PCHG2":15.68032,"CHG":13.67251,"PCHG":359.70723,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-07-24 15:41:39","ADY":257,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-302","SUBJID":"id-302","SITEID":"CHN-16","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.79834,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-06","TRTSDTM":"2020-11-09 15:41:39","TRTEDTM":"2022-02-12 23:22:15","TRT01SDTM":"2020-11-09 15:41:39","TRT01EDTM":"2021-02-12 17:22:15","TRT02SDTM":"2021-02-12 17:22:15","TRT02EDTM":"2022-02-12 23:22:15","AP01SDTM":"2020-11-09 15:41:39","AP01EDTM":"2021-02-12 17:22:15","AP02SDTM":"2021-02-12 17:22:15","AP02EDTM":"2022-02-12 23:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":461,"DCSREAS":"DEATH","DTHDT":"2022-03-15","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-15","DTHADY":490,"ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2017,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.78904,"AVALU":"U/L","BASE2":15.10501,"BASE":3.80101,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.68403,"PCHG2":77.35205,"CHG":22.98803,"PCHG":604.7873,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-08-27 15:41:39","ADY":291,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-302","SUBJID":"id-302","SITEID":"CHN-16","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.79834,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-06","TRTSDTM":"2020-11-09 15:41:39","TRTEDTM":"2022-02-12 23:22:15","TRT01SDTM":"2020-11-09 15:41:39","TRT01EDTM":"2021-02-12 17:22:15","TRT02SDTM":"2021-02-12 17:22:15","TRT02EDTM":"2022-02-12 23:22:15","AP01SDTM":"2020-11-09 15:41:39","AP01EDTM":"2021-02-12 17:22:15","AP02SDTM":"2021-02-12 17:22:15","AP02EDTM":"2022-02-12 23:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":461,"DCSREAS":"DEATH","DTHDT":"2022-03-15","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-15","DTHADY":490,"ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5349,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.36216,"AVALU":"mg/L","BASE2":8.36216,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-21 15:41:39","ADY":12,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-302","SUBJID":"id-302","SITEID":"CHN-16","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.79834,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-06","TRTSDTM":"2020-11-09 15:41:39","TRTEDTM":"2022-02-12 23:22:15","TRT01SDTM":"2020-11-09 15:41:39","TRT01EDTM":"2021-02-12 17:22:15","TRT02SDTM":"2021-02-12 17:22:15","TRT02EDTM":"2022-02-12 23:22:15","AP01SDTM":"2020-11-09 15:41:39","AP01EDTM":"2021-02-12 17:22:15","AP02SDTM":"2021-02-12 17:22:15","AP02EDTM":"2022-02-12 23:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":461,"DCSREAS":"DEATH","DTHDT":"2022-03-15","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-15","DTHADY":490,"ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8043,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.96727,"AVALU":"mg/L","BASE2":8.36216,"BASE":9.96727,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.6051,"PCHG2":19.19485,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-19 15:41:39","ADY":40,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-302","SUBJID":"id-302","SITEID":"CHN-16","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.79834,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-06","TRTSDTM":"2020-11-09 15:41:39","TRTEDTM":"2022-02-12 23:22:15","TRT01SDTM":"2020-11-09 15:41:39","TRT01EDTM":"2021-02-12 17:22:15","TRT02SDTM":"2021-02-12 17:22:15","TRT02EDTM":"2022-02-12 23:22:15","AP01SDTM":"2020-11-09 15:41:39","AP01EDTM":"2021-02-12 17:22:15","AP02SDTM":"2021-02-12 17:22:15","AP02EDTM":"2022-02-12 23:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":461,"DCSREAS":"DEATH","DTHDT":"2022-03-15","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-15","DTHADY":490,"ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4927,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.33414,"AVALU":"mg/L","BASE2":8.36216,"BASE":9.96727,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.97198,"PCHG2":23.58213,"CHG":0.36687,"PCHG":3.68077,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-12-31 15:41:39","ADY":52,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-302","SUBJID":"id-302","SITEID":"CHN-16","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.79834,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-06","TRTSDTM":"2020-11-09 15:41:39","TRTEDTM":"2022-02-12 23:22:15","TRT01SDTM":"2020-11-09 15:41:39","TRT01EDTM":"2021-02-12 17:22:15","TRT02SDTM":"2021-02-12 17:22:15","TRT02EDTM":"2022-02-12 23:22:15","AP01SDTM":"2020-11-09 15:41:39","AP01EDTM":"2021-02-12 17:22:15","AP02SDTM":"2021-02-12 17:22:15","AP02EDTM":"2022-02-12 23:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":461,"DCSREAS":"DEATH","DTHDT":"2022-03-15","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-15","DTHADY":490,"ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2417,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.5004,"AVALU":"mg/L","BASE2":8.36216,"BASE":9.96727,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13824,"PCHG2":1.65316,"CHG":-1.46686,"PCHG":-14.71681,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-21 15:41:39","ADY":73,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-302","SUBJID":"id-302","SITEID":"CHN-16","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.79834,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-06","TRTSDTM":"2020-11-09 15:41:39","TRTEDTM":"2022-02-12 23:22:15","TRT01SDTM":"2020-11-09 15:41:39","TRT01EDTM":"2021-02-12 17:22:15","TRT02SDTM":"2021-02-12 17:22:15","TRT02EDTM":"2022-02-12 23:22:15","AP01SDTM":"2020-11-09 15:41:39","AP01EDTM":"2021-02-12 17:22:15","AP02SDTM":"2021-02-12 17:22:15","AP02EDTM":"2022-02-12 23:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":461,"DCSREAS":"DEATH","DTHDT":"2022-03-15","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-15","DTHADY":490,"ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5049,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.11903,"AVALU":"mg/L","BASE2":8.36216,"BASE":9.96727,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.24313,"PCHG2":-14.86614,"CHG":-2.84824,"PCHG":-28.57589,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-04-19 15:41:39","ADY":161,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-302","SUBJID":"id-302","SITEID":"CHN-16","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.79834,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-06","TRTSDTM":"2020-11-09 15:41:39","TRTEDTM":"2022-02-12 23:22:15","TRT01SDTM":"2020-11-09 15:41:39","TRT01EDTM":"2021-02-12 17:22:15","TRT02SDTM":"2021-02-12 17:22:15","TRT02EDTM":"2022-02-12 23:22:15","AP01SDTM":"2020-11-09 15:41:39","AP01EDTM":"2021-02-12 17:22:15","AP02SDTM":"2021-02-12 17:22:15","AP02EDTM":"2022-02-12 23:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":461,"DCSREAS":"DEATH","DTHDT":"2022-03-15","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-15","DTHADY":490,"ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2582,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.30869,"AVALU":"mg/L","BASE2":8.36216,"BASE":9.96727,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.94653,"PCHG2":11.31919,"CHG":-0.65858,"PCHG":-6.60738,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-24 15:41:39","ADY":257,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-302","SUBJID":"id-302","SITEID":"CHN-16","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.79834,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-06","TRTSDTM":"2020-11-09 15:41:39","TRTEDTM":"2022-02-12 23:22:15","TRT01SDTM":"2020-11-09 15:41:39","TRT01EDTM":"2021-02-12 17:22:15","TRT02SDTM":"2021-02-12 17:22:15","TRT02EDTM":"2022-02-12 23:22:15","AP01SDTM":"2020-11-09 15:41:39","AP01EDTM":"2021-02-12 17:22:15","AP02SDTM":"2021-02-12 17:22:15","AP02EDTM":"2022-02-12 23:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":461,"DCSREAS":"DEATH","DTHDT":"2022-03-15","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-15","DTHADY":490,"ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5010,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.89826,"AVALU":"mg/L","BASE2":8.36216,"BASE":9.96727,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.53609,"PCHG2":18.36953,"CHG":-0.06901,"PCHG":-0.69241,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-27 15:41:39","ADY":291,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-302","SUBJID":"id-302","SITEID":"CHN-16","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.79834,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-06","TRTSDTM":"2020-11-09 15:41:39","TRTEDTM":"2022-02-12 23:22:15","TRT01SDTM":"2020-11-09 15:41:39","TRT01EDTM":"2021-02-12 17:22:15","TRT02SDTM":"2021-02-12 17:22:15","TRT02EDTM":"2022-02-12 23:22:15","AP01SDTM":"2020-11-09 15:41:39","AP01EDTM":"2021-02-12 17:22:15","AP02SDTM":"2021-02-12 17:22:15","AP02EDTM":"2022-02-12 23:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":461,"DCSREAS":"DEATH","DTHDT":"2022-03-15","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-15","DTHADY":490,"ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5199,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.1072,"AVALU":"g/L","BASE2":3.1072,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-11-21 15:41:39","ADY":12,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-302","SUBJID":"id-302","SITEID":"CHN-16","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.79834,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-06","TRTSDTM":"2020-11-09 15:41:39","TRTEDTM":"2022-02-12 23:22:15","TRT01SDTM":"2020-11-09 15:41:39","TRT01EDTM":"2021-02-12 17:22:15","TRT02SDTM":"2021-02-12 17:22:15","TRT02EDTM":"2022-02-12 23:22:15","AP01SDTM":"2020-11-09 15:41:39","AP01EDTM":"2021-02-12 17:22:15","AP02SDTM":"2021-02-12 17:22:15","AP02EDTM":"2022-02-12 23:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":461,"DCSREAS":"DEATH","DTHDT":"2022-03-15","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-15","DTHADY":490,"ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":46,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8518,"AVALU":"g/L","BASE2":3.1072,"BASE":2.8518,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.2554,"PCHG2":-8.21963,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-19 15:41:39","ADY":40,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-302","SUBJID":"id-302","SITEID":"CHN-16","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.79834,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-06","TRTSDTM":"2020-11-09 15:41:39","TRTEDTM":"2022-02-12 23:22:15","TRT01SDTM":"2020-11-09 15:41:39","TRT01EDTM":"2021-02-12 17:22:15","TRT02SDTM":"2021-02-12 17:22:15","TRT02EDTM":"2022-02-12 23:22:15","AP01SDTM":"2020-11-09 15:41:39","AP01EDTM":"2021-02-12 17:22:15","AP02SDTM":"2021-02-12 17:22:15","AP02EDTM":"2022-02-12 23:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":461,"DCSREAS":"DEATH","DTHDT":"2022-03-15","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-15","DTHADY":490,"ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4997,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92239,"AVALU":"g/L","BASE2":3.1072,"BASE":2.8518,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1848,"PCHG2":-5.94762,"CHG":0.0706,"PCHG":2.47548,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-31 15:41:39","ADY":52,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-302","SUBJID":"id-302","SITEID":"CHN-16","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.79834,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-06","TRTSDTM":"2020-11-09 15:41:39","TRTEDTM":"2022-02-12 23:22:15","TRT01SDTM":"2020-11-09 15:41:39","TRT01EDTM":"2021-02-12 17:22:15","TRT02SDTM":"2021-02-12 17:22:15","TRT02EDTM":"2022-02-12 23:22:15","AP01SDTM":"2020-11-09 15:41:39","AP01EDTM":"2021-02-12 17:22:15","AP02SDTM":"2021-02-12 17:22:15","AP02EDTM":"2022-02-12 23:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":461,"DCSREAS":"DEATH","DTHDT":"2022-03-15","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-15","DTHADY":490,"ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7297,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84034,"AVALU":"g/L","BASE2":3.1072,"BASE":2.8518,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.26686,"PCHG2":-8.58836,"CHG":-0.01146,"PCHG":-0.40176,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-21 15:41:39","ADY":73,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-302","SUBJID":"id-302","SITEID":"CHN-16","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.79834,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-06","TRTSDTM":"2020-11-09 15:41:39","TRTEDTM":"2022-02-12 23:22:15","TRT01SDTM":"2020-11-09 15:41:39","TRT01EDTM":"2021-02-12 17:22:15","TRT02SDTM":"2021-02-12 17:22:15","TRT02EDTM":"2022-02-12 23:22:15","AP01SDTM":"2020-11-09 15:41:39","AP01EDTM":"2021-02-12 17:22:15","AP02SDTM":"2021-02-12 17:22:15","AP02EDTM":"2022-02-12 23:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":461,"DCSREAS":"DEATH","DTHDT":"2022-03-15","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-15","DTHADY":490,"ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3438,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90609,"AVALU":"g/L","BASE2":3.1072,"BASE":2.8518,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20111,"PCHG2":-6.47244,"CHG":0.05429,"PCHG":1.90366,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-19 15:41:39","ADY":161,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-302","SUBJID":"id-302","SITEID":"CHN-16","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.79834,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-06","TRTSDTM":"2020-11-09 15:41:39","TRTEDTM":"2022-02-12 23:22:15","TRT01SDTM":"2020-11-09 15:41:39","TRT01EDTM":"2021-02-12 17:22:15","TRT02SDTM":"2021-02-12 17:22:15","TRT02EDTM":"2022-02-12 23:22:15","AP01SDTM":"2020-11-09 15:41:39","AP01EDTM":"2021-02-12 17:22:15","AP02SDTM":"2021-02-12 17:22:15","AP02EDTM":"2022-02-12 23:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":461,"DCSREAS":"DEATH","DTHDT":"2022-03-15","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-15","DTHADY":490,"ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6324,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.08331,"AVALU":"g/L","BASE2":3.1072,"BASE":2.8518,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02389,"PCHG2":-0.76882,"CHG":0.23151,"PCHG":8.11808,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-07-24 15:41:39","ADY":257,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-302","SUBJID":"id-302","SITEID":"CHN-16","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.79834,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-06","TRTSDTM":"2020-11-09 15:41:39","TRTEDTM":"2022-02-12 23:22:15","TRT01SDTM":"2020-11-09 15:41:39","TRT01EDTM":"2021-02-12 17:22:15","TRT02SDTM":"2021-02-12 17:22:15","TRT02EDTM":"2022-02-12 23:22:15","AP01SDTM":"2020-11-09 15:41:39","AP01EDTM":"2021-02-12 17:22:15","AP02SDTM":"2021-02-12 17:22:15","AP02EDTM":"2022-02-12 23:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":461,"DCSREAS":"DEATH","DTHDT":"2022-03-15","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-15","DTHADY":490,"ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5906,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95835,"AVALU":"g/L","BASE2":3.1072,"BASE":2.8518,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14885,"PCHG2":-4.79048,"CHG":0.10655,"PCHG":3.73625,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-27 15:41:39","ADY":291,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-323","SUBJID":"id-323","SITEID":"CHN-16","AGE":51,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.94449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-25 20:10:27","TRT01SDTM":"2019-12-25 20:10:27","AP01SDTM":"2019-12-25 20:10:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8022,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":36.69291,"AVALU":"U/L","BASE2":36.69291,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-19 20:10:27","ADY":56,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-323","SUBJID":"id-323","SITEID":"CHN-16","AGE":51,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.94449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-25 20:10:27","TRT01SDTM":"2019-12-25 20:10:27","AP01SDTM":"2019-12-25 20:10:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6849,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.85007,"AVALU":"U/L","BASE2":36.69291,"BASE":9.85007,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-26.84284,"PCHG2":-73.15538,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-18 20:10:27","ADY":329,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-323","SUBJID":"id-323","SITEID":"CHN-16","AGE":51,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.94449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-25 20:10:27","TRT01SDTM":"2019-12-25 20:10:27","AP01SDTM":"2019-12-25 20:10:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8053,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.92178,"AVALU":"U/L","BASE2":36.69291,"BASE":9.85007,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-19.77113,"PCHG2":-53.88269,"CHG":7.07171,"PCHG":71.79349,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-24 20:10:27","ADY":335,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-323","SUBJID":"id-323","SITEID":"CHN-16","AGE":51,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.94449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-25 20:10:27","TRT01SDTM":"2019-12-25 20:10:27","AP01SDTM":"2019-12-25 20:10:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1651,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.1265,"AVALU":"U/L","BASE2":36.69291,"BASE":9.85007,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-26.56641,"PCHG2":-72.40202,"CHG":0.27643,"PCHG":2.80637,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-13 20:10:27","ADY":475,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-323","SUBJID":"id-323","SITEID":"CHN-16","AGE":51,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.94449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-25 20:10:27","TRT01SDTM":"2019-12-25 20:10:27","AP01SDTM":"2019-12-25 20:10:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3896,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.99148,"AVALU":"U/L","BASE2":36.69291,"BASE":9.85007,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-29.70142,"PCHG2":-80.94595,"CHG":-2.85859,"PCHG":-29.02098,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-07-08 20:10:27","ADY":561,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-323","SUBJID":"id-323","SITEID":"CHN-16","AGE":51,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.94449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-25 20:10:27","TRT01SDTM":"2019-12-25 20:10:27","AP01SDTM":"2019-12-25 20:10:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3214,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.84449,"AVALU":"U/L","BASE2":36.69291,"BASE":9.85007,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-32.84841,"PCHG2":-89.52251,"CHG":-6.00558,"PCHG":-60.96988,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-08-07 20:10:27","ADY":591,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-323","SUBJID":"id-323","SITEID":"CHN-16","AGE":51,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.94449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-25 20:10:27","TRT01SDTM":"2019-12-25 20:10:27","AP01SDTM":"2019-12-25 20:10:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2311,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.82611,"AVALU":"U/L","BASE2":36.69291,"BASE":9.85007,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-18.8668,"PCHG2":-51.4181,"CHG":7.97604,"PCHG":80.97445,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-17 20:10:27","ADY":693,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-323","SUBJID":"id-323","SITEID":"CHN-16","AGE":51,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.94449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-25 20:10:27","TRT01SDTM":"2019-12-25 20:10:27","AP01SDTM":"2019-12-25 20:10:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1031,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.67227,"AVALU":"mg/L","BASE2":8.67227,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-19 20:10:27","ADY":56,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-323","SUBJID":"id-323","SITEID":"CHN-16","AGE":51,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.94449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-25 20:10:27","TRT01SDTM":"2019-12-25 20:10:27","AP01SDTM":"2019-12-25 20:10:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8007,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.42222,"AVALU":"mg/L","BASE2":8.67227,"BASE":9.42222,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.74996,"PCHG2":8.64778,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-18 20:10:27","ADY":329,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-323","SUBJID":"id-323","SITEID":"CHN-16","AGE":51,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.94449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-25 20:10:27","TRT01SDTM":"2019-12-25 20:10:27","AP01SDTM":"2019-12-25 20:10:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4021,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.22565,"AVALU":"mg/L","BASE2":8.67227,"BASE":9.42222,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.44661,"PCHG2":-5.14992,"CHG":-1.19657,"PCHG":-12.69947,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-24 20:10:27","ADY":335,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-323","SUBJID":"id-323","SITEID":"CHN-16","AGE":51,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.94449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-25 20:10:27","TRT01SDTM":"2019-12-25 20:10:27","AP01SDTM":"2019-12-25 20:10:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1669,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.45886,"AVALU":"mg/L","BASE2":8.67227,"BASE":9.42222,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.2134,"PCHG2":-2.46077,"CHG":-0.96336,"PCHG":-10.22437,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-13 20:10:27","ADY":475,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-323","SUBJID":"id-323","SITEID":"CHN-16","AGE":51,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.94449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-25 20:10:27","TRT01SDTM":"2019-12-25 20:10:27","AP01SDTM":"2019-12-25 20:10:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":359,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.10221,"AVALU":"mg/L","BASE2":8.67227,"BASE":9.42222,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.57005,"PCHG2":-6.57326,"CHG":-1.32001,"PCHG":-14.00952,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-08 20:10:27","ADY":561,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-323","SUBJID":"id-323","SITEID":"CHN-16","AGE":51,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.94449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-25 20:10:27","TRT01SDTM":"2019-12-25 20:10:27","AP01SDTM":"2019-12-25 20:10:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1912,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.83315,"AVALU":"mg/L","BASE2":8.67227,"BASE":9.42222,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16089,"PCHG2":1.85519,"CHG":-0.58907,"PCHG":-6.25194,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-07 20:10:27","ADY":591,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-323","SUBJID":"id-323","SITEID":"CHN-16","AGE":51,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.94449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-25 20:10:27","TRT01SDTM":"2019-12-25 20:10:27","AP01SDTM":"2019-12-25 20:10:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1049,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.88511,"AVALU":"mg/L","BASE2":8.67227,"BASE":9.42222,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.78715,"PCHG2":-9.07668,"CHG":-1.53711,"PCHG":-16.31369,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-11-17 20:10:27","ADY":693,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-323","SUBJID":"id-323","SITEID":"CHN-16","AGE":51,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.94449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-25 20:10:27","TRT01SDTM":"2019-12-25 20:10:27","AP01SDTM":"2019-12-25 20:10:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4236,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88085,"AVALU":"g/L","BASE2":2.88085,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-19 20:10:27","ADY":56,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-323","SUBJID":"id-323","SITEID":"CHN-16","AGE":51,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.94449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-25 20:10:27","TRT01SDTM":"2019-12-25 20:10:27","AP01SDTM":"2019-12-25 20:10:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4974,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77656,"AVALU":"g/L","BASE2":2.88085,"BASE":2.77656,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.10429,"PCHG2":-3.62009,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-18 20:10:27","ADY":329,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-323","SUBJID":"id-323","SITEID":"CHN-16","AGE":51,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.94449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-25 20:10:27","TRT01SDTM":"2019-12-25 20:10:27","AP01SDTM":"2019-12-25 20:10:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1946,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02078,"AVALU":"g/L","BASE2":2.88085,"BASE":2.77656,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13993,"PCHG2":4.85727,"CHG":0.24422,"PCHG":8.79577,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-11-24 20:10:27","ADY":335,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-323","SUBJID":"id-323","SITEID":"CHN-16","AGE":51,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.94449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-25 20:10:27","TRT01SDTM":"2019-12-25 20:10:27","AP01SDTM":"2019-12-25 20:10:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2945,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7951,"AVALU":"g/L","BASE2":2.88085,"BASE":2.77656,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08575,"PCHG2":-2.97663,"CHG":0.01854,"PCHG":0.66763,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-13 20:10:27","ADY":475,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-323","SUBJID":"id-323","SITEID":"CHN-16","AGE":51,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.94449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-25 20:10:27","TRT01SDTM":"2019-12-25 20:10:27","AP01SDTM":"2019-12-25 20:10:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4941,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9533,"AVALU":"g/L","BASE2":2.88085,"BASE":2.77656,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07245,"PCHG2":2.51473,"CHG":0.17673,"PCHG":6.36524,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-08 20:10:27","ADY":561,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-323","SUBJID":"id-323","SITEID":"CHN-16","AGE":51,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.94449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-25 20:10:27","TRT01SDTM":"2019-12-25 20:10:27","AP01SDTM":"2019-12-25 20:10:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6497,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97727,"AVALU":"g/L","BASE2":2.88085,"BASE":2.77656,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09642,"PCHG2":3.34703,"CHG":0.20071,"PCHG":7.2288,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-07 20:10:27","ADY":591,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-323","SUBJID":"id-323","SITEID":"CHN-16","AGE":51,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.94449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-25 20:10:27","TRT01SDTM":"2019-12-25 20:10:27","AP01SDTM":"2019-12-25 20:10:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5381,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91683,"AVALU":"g/L","BASE2":2.88085,"BASE":2.77656,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03598,"PCHG2":1.24911,"CHG":0.14027,"PCHG":5.05208,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-17 20:10:27","ADY":693,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-352","SUBJID":"id-352","SITEID":"CHN-16","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.21681,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 09:25:56","TRTEDTM":"2024-02-03 03:25:56","TRT01SDTM":"2021-02-02 09:25:56","TRT01EDTM":"2023-02-02 21:25:56","TRT02SDTM":"2023-02-02 21:25:56","TRT02EDTM":"2024-02-03 03:25:56","AP01SDTM":"2021-02-02 09:25:56","AP01EDTM":"2023-02-02 21:25:56","AP02SDTM":"2023-02-02 21:25:56","AP02EDTM":"2024-02-03 03:25:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-14","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1621,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.75687,"AVALU":"U/L","BASE2":8.75687,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-06 09:25:56","ADY":489,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-352","SUBJID":"id-352","SITEID":"CHN-16","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.21681,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 09:25:56","TRTEDTM":"2024-02-03 03:25:56","TRT01SDTM":"2021-02-02 09:25:56","TRT01EDTM":"2023-02-02 21:25:56","TRT02SDTM":"2023-02-02 21:25:56","TRT02EDTM":"2024-02-03 03:25:56","AP01SDTM":"2021-02-02 09:25:56","AP01EDTM":"2023-02-02 21:25:56","AP02SDTM":"2023-02-02 21:25:56","AP02EDTM":"2024-02-03 03:25:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-14","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":494,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.49626,"AVALU":"U/L","BASE2":8.75687,"BASE":7.49626,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.26061,"PCHG2":-14.39571,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-15 09:25:56","ADY":743,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-352","SUBJID":"id-352","SITEID":"CHN-16","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.21681,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 09:25:56","TRTEDTM":"2024-02-03 03:25:56","TRT01SDTM":"2021-02-02 09:25:56","TRT01EDTM":"2023-02-02 21:25:56","TRT02SDTM":"2023-02-02 21:25:56","TRT02EDTM":"2024-02-03 03:25:56","AP01SDTM":"2021-02-02 09:25:56","AP01EDTM":"2023-02-02 21:25:56","AP02SDTM":"2023-02-02 21:25:56","AP02EDTM":"2024-02-03 03:25:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-14","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2399,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.98804,"AVALU":"U/L","BASE2":8.75687,"BASE":7.49626,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.23117,"PCHG2":116.83588,"CHG":11.49178,"PCHG":153.30024,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-19 09:25:56","ADY":836,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-352","SUBJID":"id-352","SITEID":"CHN-16","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.21681,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 09:25:56","TRTEDTM":"2024-02-03 03:25:56","TRT01SDTM":"2021-02-02 09:25:56","TRT01EDTM":"2023-02-02 21:25:56","TRT02SDTM":"2023-02-02 21:25:56","TRT02EDTM":"2024-02-03 03:25:56","AP01SDTM":"2021-02-02 09:25:56","AP01EDTM":"2023-02-02 21:25:56","AP02SDTM":"2023-02-02 21:25:56","AP02EDTM":"2024-02-03 03:25:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-14","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1748,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.57796,"AVALU":"U/L","BASE2":8.75687,"BASE":7.49626,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.82109,"PCHG2":89.31373,"CHG":9.0817,"PCHG":121.14981,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-28 09:25:56","ADY":876,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-352","SUBJID":"id-352","SITEID":"CHN-16","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.21681,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 09:25:56","TRTEDTM":"2024-02-03 03:25:56","TRT01SDTM":"2021-02-02 09:25:56","TRT01EDTM":"2023-02-02 21:25:56","TRT02SDTM":"2023-02-02 21:25:56","TRT02EDTM":"2024-02-03 03:25:56","AP01SDTM":"2021-02-02 09:25:56","AP01EDTM":"2023-02-02 21:25:56","AP02SDTM":"2023-02-02 21:25:56","AP02EDTM":"2024-02-03 03:25:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-14","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2377,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.82715,"AVALU":"U/L","BASE2":8.75687,"BASE":7.49626,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.07028,"PCHG2":137.83777,"CHG":13.33089,"PCHG":177.83392,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-12 09:25:56","ADY":921,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-352","SUBJID":"id-352","SITEID":"CHN-16","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.21681,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 09:25:56","TRTEDTM":"2024-02-03 03:25:56","TRT01SDTM":"2021-02-02 09:25:56","TRT01EDTM":"2023-02-02 21:25:56","TRT02SDTM":"2023-02-02 21:25:56","TRT02EDTM":"2024-02-03 03:25:56","AP01SDTM":"2021-02-02 09:25:56","AP01EDTM":"2023-02-02 21:25:56","AP02SDTM":"2023-02-02 21:25:56","AP02EDTM":"2024-02-03 03:25:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-14","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2578,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.07186,"AVALU":"U/L","BASE2":8.75687,"BASE":7.49626,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":20.31498,"PCHG2":231.98904,"CHG":21.5756,"PCHG":287.81821,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-14 09:25:56","ADY":923,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-352","SUBJID":"id-352","SITEID":"CHN-16","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.21681,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 09:25:56","TRTEDTM":"2024-02-03 03:25:56","TRT01SDTM":"2021-02-02 09:25:56","TRT01EDTM":"2023-02-02 21:25:56","TRT02SDTM":"2023-02-02 21:25:56","TRT02EDTM":"2024-02-03 03:25:56","AP01SDTM":"2021-02-02 09:25:56","AP01EDTM":"2023-02-02 21:25:56","AP02SDTM":"2023-02-02 21:25:56","AP02EDTM":"2024-02-03 03:25:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-14","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":630,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.09865,"AVALU":"U/L","BASE2":8.75687,"BASE":7.49626,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.34178,"PCHG2":38.16182,"CHG":4.6024,"PCHG":61.3959,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-10 09:25:56","ADY":950,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-352","SUBJID":"id-352","SITEID":"CHN-16","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.21681,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 09:25:56","TRTEDTM":"2024-02-03 03:25:56","TRT01SDTM":"2021-02-02 09:25:56","TRT01EDTM":"2023-02-02 21:25:56","TRT02SDTM":"2023-02-02 21:25:56","TRT02EDTM":"2024-02-03 03:25:56","AP01SDTM":"2021-02-02 09:25:56","AP01EDTM":"2023-02-02 21:25:56","AP02SDTM":"2023-02-02 21:25:56","AP02EDTM":"2024-02-03 03:25:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-14","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1450,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.32725,"AVALU":"mg/L","BASE2":10.32725,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"","ATOXGR":"2","BTOXGR":"-3","ADTM":"2022-06-06 09:25:56","ADY":489,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-352","SUBJID":"id-352","SITEID":"CHN-16","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.21681,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 09:25:56","TRTEDTM":"2024-02-03 03:25:56","TRT01SDTM":"2021-02-02 09:25:56","TRT01EDTM":"2023-02-02 21:25:56","TRT02SDTM":"2023-02-02 21:25:56","TRT02EDTM":"2024-02-03 03:25:56","AP01SDTM":"2021-02-02 09:25:56","AP01EDTM":"2023-02-02 21:25:56","AP02SDTM":"2023-02-02 21:25:56","AP02EDTM":"2024-02-03 03:25:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-14","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7358,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.52506,"AVALU":"mg/L","BASE2":10.32725,"BASE":7.52506,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.80218,"PCHG2":-27.13389,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2023-02-15 09:25:56","ADY":743,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-352","SUBJID":"id-352","SITEID":"CHN-16","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.21681,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 09:25:56","TRTEDTM":"2024-02-03 03:25:56","TRT01SDTM":"2021-02-02 09:25:56","TRT01EDTM":"2023-02-02 21:25:56","TRT02SDTM":"2023-02-02 21:25:56","TRT02EDTM":"2024-02-03 03:25:56","AP01SDTM":"2021-02-02 09:25:56","AP01EDTM":"2023-02-02 21:25:56","AP02SDTM":"2023-02-02 21:25:56","AP02EDTM":"2024-02-03 03:25:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-14","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3932,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.85054,"AVALU":"mg/L","BASE2":10.32725,"BASE":7.52506,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.52329,"PCHG2":5.06711,"CHG":3.32548,"PCHG":44.192,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"4","BTOXGR":"-3","ADTM":"2023-05-19 09:25:56","ADY":836,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-352","SUBJID":"id-352","SITEID":"CHN-16","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.21681,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 09:25:56","TRTEDTM":"2024-02-03 03:25:56","TRT01SDTM":"2021-02-02 09:25:56","TRT01EDTM":"2023-02-02 21:25:56","TRT02SDTM":"2023-02-02 21:25:56","TRT02EDTM":"2024-02-03 03:25:56","AP01SDTM":"2021-02-02 09:25:56","AP01EDTM":"2023-02-02 21:25:56","AP02SDTM":"2023-02-02 21:25:56","AP02EDTM":"2024-02-03 03:25:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-14","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7647,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.94797,"AVALU":"mg/L","BASE2":10.32725,"BASE":7.52506,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.37928,"PCHG2":-23.03884,"CHG":0.42291,"PCHG":5.61996,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-2","BTOXGR":"-3","ADTM":"2023-06-28 09:25:56","ADY":876,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-352","SUBJID":"id-352","SITEID":"CHN-16","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.21681,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 09:25:56","TRTEDTM":"2024-02-03 03:25:56","TRT01SDTM":"2021-02-02 09:25:56","TRT01EDTM":"2023-02-02 21:25:56","TRT02SDTM":"2023-02-02 21:25:56","TRT02EDTM":"2024-02-03 03:25:56","AP01SDTM":"2021-02-02 09:25:56","AP01EDTM":"2023-02-02 21:25:56","AP02SDTM":"2023-02-02 21:25:56","AP02EDTM":"2024-02-03 03:25:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-14","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3942,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.78904,"AVALU":"mg/L","BASE2":10.32725,"BASE":7.52506,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.5382,"PCHG2":-14.89462,"CHG":1.26398,"PCHG":16.79692,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2023-08-12 09:25:56","ADY":921,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-352","SUBJID":"id-352","SITEID":"CHN-16","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.21681,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 09:25:56","TRTEDTM":"2024-02-03 03:25:56","TRT01SDTM":"2021-02-02 09:25:56","TRT01EDTM":"2023-02-02 21:25:56","TRT02SDTM":"2023-02-02 21:25:56","TRT02EDTM":"2024-02-03 03:25:56","AP01SDTM":"2021-02-02 09:25:56","AP01EDTM":"2023-02-02 21:25:56","AP02SDTM":"2023-02-02 21:25:56","AP02EDTM":"2024-02-03 03:25:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-14","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4957,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.58353,"AVALU":"mg/L","BASE2":10.32725,"BASE":7.52506,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.74371,"PCHG2":-7.20148,"CHG":2.05847,"PCHG":27.35483,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2023-08-14 09:25:56","ADY":923,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-352","SUBJID":"id-352","SITEID":"CHN-16","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.21681,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 09:25:56","TRTEDTM":"2024-02-03 03:25:56","TRT01SDTM":"2021-02-02 09:25:56","TRT01EDTM":"2023-02-02 21:25:56","TRT02SDTM":"2023-02-02 21:25:56","TRT02EDTM":"2024-02-03 03:25:56","AP01SDTM":"2021-02-02 09:25:56","AP01EDTM":"2023-02-02 21:25:56","AP02SDTM":"2023-02-02 21:25:56","AP02EDTM":"2024-02-03 03:25:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-14","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":844,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.7284,"AVALU":"mg/L","BASE2":10.32725,"BASE":7.52506,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.59885,"PCHG2":-25.16496,"CHG":0.20334,"PCHG":2.70211,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2023-09-10 09:25:56","ADY":950,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-352","SUBJID":"id-352","SITEID":"CHN-16","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.21681,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 09:25:56","TRTEDTM":"2024-02-03 03:25:56","TRT01SDTM":"2021-02-02 09:25:56","TRT01EDTM":"2023-02-02 21:25:56","TRT02SDTM":"2023-02-02 21:25:56","TRT02EDTM":"2024-02-03 03:25:56","AP01SDTM":"2021-02-02 09:25:56","AP01EDTM":"2023-02-02 21:25:56","AP02SDTM":"2023-02-02 21:25:56","AP02EDTM":"2024-02-03 03:25:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-14","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1605,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9561,"AVALU":"g/L","BASE2":2.9561,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-06 09:25:56","ADY":489,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-352","SUBJID":"id-352","SITEID":"CHN-16","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.21681,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 09:25:56","TRTEDTM":"2024-02-03 03:25:56","TRT01SDTM":"2021-02-02 09:25:56","TRT01EDTM":"2023-02-02 21:25:56","TRT02SDTM":"2023-02-02 21:25:56","TRT02EDTM":"2024-02-03 03:25:56","AP01SDTM":"2021-02-02 09:25:56","AP01EDTM":"2023-02-02 21:25:56","AP02SDTM":"2023-02-02 21:25:56","AP02EDTM":"2024-02-03 03:25:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-14","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1728,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95017,"AVALU":"g/L","BASE2":2.9561,"BASE":2.95017,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.00593,"PCHG2":-0.20052,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-15 09:25:56","ADY":743,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-352","SUBJID":"id-352","SITEID":"CHN-16","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.21681,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 09:25:56","TRTEDTM":"2024-02-03 03:25:56","TRT01SDTM":"2021-02-02 09:25:56","TRT01EDTM":"2023-02-02 21:25:56","TRT02SDTM":"2023-02-02 21:25:56","TRT02EDTM":"2024-02-03 03:25:56","AP01SDTM":"2021-02-02 09:25:56","AP01EDTM":"2023-02-02 21:25:56","AP02SDTM":"2023-02-02 21:25:56","AP02EDTM":"2024-02-03 03:25:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-14","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6039,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90814,"AVALU":"g/L","BASE2":2.9561,"BASE":2.95017,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04796,"PCHG2":-1.62246,"CHG":-0.04203,"PCHG":-1.4248,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-19 09:25:56","ADY":836,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-352","SUBJID":"id-352","SITEID":"CHN-16","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.21681,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 09:25:56","TRTEDTM":"2024-02-03 03:25:56","TRT01SDTM":"2021-02-02 09:25:56","TRT01EDTM":"2023-02-02 21:25:56","TRT02SDTM":"2023-02-02 21:25:56","TRT02EDTM":"2024-02-03 03:25:56","AP01SDTM":"2021-02-02 09:25:56","AP01EDTM":"2023-02-02 21:25:56","AP02SDTM":"2023-02-02 21:25:56","AP02EDTM":"2024-02-03 03:25:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-14","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2834,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90364,"AVALU":"g/L","BASE2":2.9561,"BASE":2.95017,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05246,"PCHG2":-1.77473,"CHG":-0.04654,"PCHG":-1.57738,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-28 09:25:56","ADY":876,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-352","SUBJID":"id-352","SITEID":"CHN-16","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.21681,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 09:25:56","TRTEDTM":"2024-02-03 03:25:56","TRT01SDTM":"2021-02-02 09:25:56","TRT01EDTM":"2023-02-02 21:25:56","TRT02SDTM":"2023-02-02 21:25:56","TRT02EDTM":"2024-02-03 03:25:56","AP01SDTM":"2021-02-02 09:25:56","AP01EDTM":"2023-02-02 21:25:56","AP02SDTM":"2023-02-02 21:25:56","AP02EDTM":"2024-02-03 03:25:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-14","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1555,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03789,"AVALU":"g/L","BASE2":2.9561,"BASE":2.95017,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08179,"PCHG2":2.76686,"CHG":0.08772,"PCHG":2.97333,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2023-08-12 09:25:56","ADY":921,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-352","SUBJID":"id-352","SITEID":"CHN-16","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.21681,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 09:25:56","TRTEDTM":"2024-02-03 03:25:56","TRT01SDTM":"2021-02-02 09:25:56","TRT01EDTM":"2023-02-02 21:25:56","TRT02SDTM":"2023-02-02 21:25:56","TRT02EDTM":"2024-02-03 03:25:56","AP01SDTM":"2021-02-02 09:25:56","AP01EDTM":"2023-02-02 21:25:56","AP02SDTM":"2023-02-02 21:25:56","AP02EDTM":"2024-02-03 03:25:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-14","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1922,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85681,"AVALU":"g/L","BASE2":2.9561,"BASE":2.95017,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09929,"PCHG2":-3.35869,"CHG":-0.09336,"PCHG":-3.16452,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-14 09:25:56","ADY":923,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-352","SUBJID":"id-352","SITEID":"CHN-16","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.21681,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-30","TRTSDTM":"2021-02-02 09:25:56","TRTEDTM":"2024-02-03 03:25:56","TRT01SDTM":"2021-02-02 09:25:56","TRT01EDTM":"2023-02-02 21:25:56","TRT02SDTM":"2023-02-02 21:25:56","TRT02EDTM":"2024-02-03 03:25:56","AP01SDTM":"2021-02-02 09:25:56","AP01EDTM":"2023-02-02 21:25:56","AP02SDTM":"2023-02-02 21:25:56","AP02EDTM":"2024-02-03 03:25:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-03","EOSDY":1096,"LSTALVDT":"2024-02-14","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1815,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75527,"AVALU":"g/L","BASE2":2.9561,"BASE":2.95017,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20083,"PCHG2":-6.7937,"CHG":-0.1949,"PCHG":-6.60643,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-10 09:25:56","ADY":950,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-381","SUBJID":"id-381","SITEID":"CHN-16","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.62925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-14","TRTSDTM":"2020-02-15 07:36:20","TRT01SDTM":"2020-02-15 07:36:20","AP01SDTM":"2020-02-15 07:36:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5936,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.11975,"AVALU":"U/L","BASE2":22.11975,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-06 07:36:20","ADY":20,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-381","SUBJID":"id-381","SITEID":"CHN-16","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.62925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-14","TRTSDTM":"2020-02-15 07:36:20","TRT01SDTM":"2020-02-15 07:36:20","AP01SDTM":"2020-02-15 07:36:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3366,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.99903,"AVALU":"U/L","BASE2":22.11975,"BASE":18.99903,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-3.12071,"PCHG2":-14.10827,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-14 07:36:20","ADY":273,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-381","SUBJID":"id-381","SITEID":"CHN-16","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.62925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-14","TRTSDTM":"2020-02-15 07:36:20","TRT01SDTM":"2020-02-15 07:36:20","AP01SDTM":"2020-02-15 07:36:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4888,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.26628,"AVALU":"U/L","BASE2":22.11975,"BASE":18.99903,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.14653,"PCHG2":32.30838,"CHG":10.26724,"PCHG":54.04088,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-06 07:36:20","ADY":295,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-381","SUBJID":"id-381","SITEID":"CHN-16","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.62925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-14","TRTSDTM":"2020-02-15 07:36:20","TRT01SDTM":"2020-02-15 07:36:20","AP01SDTM":"2020-02-15 07:36:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":861,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.52861,"AVALU":"U/L","BASE2":22.11975,"BASE":18.99903,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.59114,"PCHG2":-38.83922,"CHG":-5.47042,"PCHG":-28.79317,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-25 07:36:20","ADY":314,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-381","SUBJID":"id-381","SITEID":"CHN-16","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.62925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-14","TRTSDTM":"2020-02-15 07:36:20","TRT01SDTM":"2020-02-15 07:36:20","AP01SDTM":"2020-02-15 07:36:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":96,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.96506,"AVALU":"U/L","BASE2":22.11975,"BASE":18.99903,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.15469,"PCHG2":-18.78272,"CHG":-1.03398,"PCHG":-5.44226,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-11 07:36:20","ADY":543,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-381","SUBJID":"id-381","SITEID":"CHN-16","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.62925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-14","TRTSDTM":"2020-02-15 07:36:20","TRT01SDTM":"2020-02-15 07:36:20","AP01SDTM":"2020-02-15 07:36:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2648,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":41.27405,"AVALU":"U/L","BASE2":22.11975,"BASE":18.99903,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.15431,"PCHG2":86.5937,"CHG":22.27502,"PCHG":117.24291,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-10 07:36:20","ADY":603,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-381","SUBJID":"id-381","SITEID":"CHN-16","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.62925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-14","TRTSDTM":"2020-02-15 07:36:20","TRT01SDTM":"2020-02-15 07:36:20","AP01SDTM":"2020-02-15 07:36:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1763,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.159,"AVALU":"U/L","BASE2":22.11975,"BASE":18.99903,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.03925,"PCHG2":45.38592,"CHG":13.15996,"PCHG":69.26649,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-08 07:36:20","ADY":693,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-381","SUBJID":"id-381","SITEID":"CHN-16","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.62925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-14","TRTSDTM":"2020-02-15 07:36:20","TRT01SDTM":"2020-02-15 07:36:20","AP01SDTM":"2020-02-15 07:36:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3405,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.0344,"AVALU":"mg/L","BASE2":9.0344,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-06 07:36:20","ADY":20,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-381","SUBJID":"id-381","SITEID":"CHN-16","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.62925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-14","TRTSDTM":"2020-02-15 07:36:20","TRT01SDTM":"2020-02-15 07:36:20","AP01SDTM":"2020-02-15 07:36:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":839,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.93097,"AVALU":"mg/L","BASE2":9.0344,"BASE":9.93097,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.89656,"PCHG2":9.9239,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-14 07:36:20","ADY":273,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-381","SUBJID":"id-381","SITEID":"CHN-16","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.62925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-14","TRTSDTM":"2020-02-15 07:36:20","TRT01SDTM":"2020-02-15 07:36:20","AP01SDTM":"2020-02-15 07:36:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4686,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.28086,"AVALU":"mg/L","BASE2":9.0344,"BASE":9.93097,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.24645,"PCHG2":2.72793,"CHG":-0.65011,"PCHG":-6.54631,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-06 07:36:20","ADY":295,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-381","SUBJID":"id-381","SITEID":"CHN-16","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.62925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-14","TRTSDTM":"2020-02-15 07:36:20","TRT01SDTM":"2020-02-15 07:36:20","AP01SDTM":"2020-02-15 07:36:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":973,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.0954,"AVALU":"mg/L","BASE2":9.0344,"BASE":9.93097,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06099,"PCHG2":0.67511,"CHG":-0.83557,"PCHG":-8.41381,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-25 07:36:20","ADY":314,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-381","SUBJID":"id-381","SITEID":"CHN-16","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.62925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-14","TRTSDTM":"2020-02-15 07:36:20","TRT01SDTM":"2020-02-15 07:36:20","AP01SDTM":"2020-02-15 07:36:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1696,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.50952,"AVALU":"mg/L","BASE2":9.0344,"BASE":9.93097,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.52488,"PCHG2":-16.87863,"CHG":-2.42145,"PCHG":-24.3828,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-08-11 07:36:20","ADY":543,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-381","SUBJID":"id-381","SITEID":"CHN-16","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.62925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-14","TRTSDTM":"2020-02-15 07:36:20","TRT01SDTM":"2020-02-15 07:36:20","AP01SDTM":"2020-02-15 07:36:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7860,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.05345,"AVALU":"mg/L","BASE2":9.0344,"BASE":9.93097,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01905,"PCHG2":0.21082,"CHG":-0.87752,"PCHG":-8.83618,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-10 07:36:20","ADY":603,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-381","SUBJID":"id-381","SITEID":"CHN-16","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.62925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-14","TRTSDTM":"2020-02-15 07:36:20","TRT01SDTM":"2020-02-15 07:36:20","AP01SDTM":"2020-02-15 07:36:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7492,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.65869,"AVALU":"mg/L","BASE2":9.0344,"BASE":9.93097,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.62429,"PCHG2":6.91009,"CHG":-0.27228,"PCHG":-2.74172,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-08 07:36:20","ADY":693,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-381","SUBJID":"id-381","SITEID":"CHN-16","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.62925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-14","TRTSDTM":"2020-02-15 07:36:20","TRT01SDTM":"2020-02-15 07:36:20","AP01SDTM":"2020-02-15 07:36:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5005,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84318,"AVALU":"g/L","BASE2":2.84318,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-03-06 07:36:20","ADY":20,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-381","SUBJID":"id-381","SITEID":"CHN-16","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.62925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-14","TRTSDTM":"2020-02-15 07:36:20","TRT01SDTM":"2020-02-15 07:36:20","AP01SDTM":"2020-02-15 07:36:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1452,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04244,"AVALU":"g/L","BASE2":2.84318,"BASE":3.04244,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.19926,"PCHG2":7.00832,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2020-11-14 07:36:20","ADY":273,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-381","SUBJID":"id-381","SITEID":"CHN-16","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.62925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-14","TRTSDTM":"2020-02-15 07:36:20","TRT01SDTM":"2020-02-15 07:36:20","AP01SDTM":"2020-02-15 07:36:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":898,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80242,"AVALU":"g/L","BASE2":2.84318,"BASE":3.04244,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04076,"PCHG2":-1.43359,"CHG":-0.24002,"PCHG":-7.88902,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-12-06 07:36:20","ADY":295,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-381","SUBJID":"id-381","SITEID":"CHN-16","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.62925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-14","TRTSDTM":"2020-02-15 07:36:20","TRT01SDTM":"2020-02-15 07:36:20","AP01SDTM":"2020-02-15 07:36:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1570,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91845,"AVALU":"g/L","BASE2":2.84318,"BASE":3.04244,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07526,"PCHG2":2.64721,"CHG":-0.12399,"PCHG":-4.07549,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-12-25 07:36:20","ADY":314,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-381","SUBJID":"id-381","SITEID":"CHN-16","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.62925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-14","TRTSDTM":"2020-02-15 07:36:20","TRT01SDTM":"2020-02-15 07:36:20","AP01SDTM":"2020-02-15 07:36:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7235,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94312,"AVALU":"g/L","BASE2":2.84318,"BASE":3.04244,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09993,"PCHG2":3.51481,"CHG":-0.09933,"PCHG":-3.26471,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-08-11 07:36:20","ADY":543,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-381","SUBJID":"id-381","SITEID":"CHN-16","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.62925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-14","TRTSDTM":"2020-02-15 07:36:20","TRT01SDTM":"2020-02-15 07:36:20","AP01SDTM":"2020-02-15 07:36:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7933,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93033,"AVALU":"g/L","BASE2":2.84318,"BASE":3.04244,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08715,"PCHG2":3.06507,"CHG":-0.11211,"PCHG":-3.685,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-10-10 07:36:20","ADY":603,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-16-id-381","SUBJID":"id-381","SITEID":"CHN-16","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-16","INVNAM":"Dr. CHN-16 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.62925,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-14","TRTSDTM":"2020-02-15 07:36:20","TRT01SDTM":"2020-02-15 07:36:20","AP01SDTM":"2020-02-15 07:36:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1421,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92286,"AVALU":"g/L","BASE2":2.84318,"BASE":3.04244,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07968,"PCHG2":2.8025,"CHG":-0.11958,"PCHG":-3.93037,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-01-08 07:36:20","ADY":693,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-10","SUBJID":"id-10","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.58058,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-17 01:03:47","TRTEDTM":"2023-12-17 19:03:47","TRT01SDTM":"2020-12-17 01:03:47","TRT01EDTM":"2022-12-17 13:03:47","TRT02SDTM":"2022-12-17 13:03:47","TRT02EDTM":"2023-12-17 19:03:47","AP01SDTM":"2020-12-17 01:03:47","AP01EDTM":"2022-12-17 13:03:47","AP02SDTM":"2022-12-17 13:03:47","AP02EDTM":"2023-12-17 19:03:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1314,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.7834,"AVALU":"U/L","BASE2":24.7834,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-01 01:03:47","ADY":531,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-10","SUBJID":"id-10","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.58058,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-17 01:03:47","TRTEDTM":"2023-12-17 19:03:47","TRT01SDTM":"2020-12-17 01:03:47","TRT01EDTM":"2022-12-17 13:03:47","TRT02SDTM":"2022-12-17 13:03:47","TRT02EDTM":"2023-12-17 19:03:47","AP01SDTM":"2020-12-17 01:03:47","AP01EDTM":"2022-12-17 13:03:47","AP02SDTM":"2022-12-17 13:03:47","AP02EDTM":"2023-12-17 19:03:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2446,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":38.19333,"AVALU":"U/L","BASE2":24.7834,"BASE":38.19333,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":13.40992,"PCHG2":54.10849,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-25 01:03:47","ADY":555,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-10","SUBJID":"id-10","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.58058,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-17 01:03:47","TRTEDTM":"2023-12-17 19:03:47","TRT01SDTM":"2020-12-17 01:03:47","TRT01EDTM":"2022-12-17 13:03:47","TRT02SDTM":"2022-12-17 13:03:47","TRT02EDTM":"2023-12-17 19:03:47","AP01SDTM":"2020-12-17 01:03:47","AP01EDTM":"2022-12-17 13:03:47","AP02SDTM":"2022-12-17 13:03:47","AP02EDTM":"2023-12-17 19:03:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1317,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.20068,"AVALU":"U/L","BASE2":24.7834,"BASE":38.19333,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.58272,"PCHG2":-66.91059,"CHG":-29.99264,"PCHG":-78.5285,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-28 01:03:47","ADY":558,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-10","SUBJID":"id-10","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.58058,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-17 01:03:47","TRTEDTM":"2023-12-17 19:03:47","TRT01SDTM":"2020-12-17 01:03:47","TRT01EDTM":"2022-12-17 13:03:47","TRT02SDTM":"2022-12-17 13:03:47","TRT02EDTM":"2023-12-17 19:03:47","AP01SDTM":"2020-12-17 01:03:47","AP01EDTM":"2022-12-17 13:03:47","AP02SDTM":"2022-12-17 13:03:47","AP02EDTM":"2023-12-17 19:03:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2690,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.99753,"AVALU":"U/L","BASE2":24.7834,"BASE":38.19333,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.78588,"PCHG2":-43.52056,"CHG":-24.1958,"PCHG":-63.35086,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-06 01:03:47","ADY":628,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-10","SUBJID":"id-10","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.58058,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-17 01:03:47","TRTEDTM":"2023-12-17 19:03:47","TRT01SDTM":"2020-12-17 01:03:47","TRT01EDTM":"2022-12-17 13:03:47","TRT02SDTM":"2022-12-17 13:03:47","TRT02EDTM":"2023-12-17 19:03:47","AP01SDTM":"2020-12-17 01:03:47","AP01EDTM":"2022-12-17 13:03:47","AP02SDTM":"2022-12-17 13:03:47","AP02EDTM":"2023-12-17 19:03:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6619,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.3364,"AVALU":"U/L","BASE2":24.7834,"BASE":38.19333,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.44701,"PCHG2":-58.29307,"CHG":-27.85693,"PCHG":-72.93664,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-23 01:03:47","ADY":767,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-10","SUBJID":"id-10","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.58058,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-17 01:03:47","TRTEDTM":"2023-12-17 19:03:47","TRT01SDTM":"2020-12-17 01:03:47","TRT01EDTM":"2022-12-17 13:03:47","TRT02SDTM":"2022-12-17 13:03:47","TRT02EDTM":"2023-12-17 19:03:47","AP01SDTM":"2020-12-17 01:03:47","AP01EDTM":"2022-12-17 13:03:47","AP02SDTM":"2022-12-17 13:03:47","AP02EDTM":"2023-12-17 19:03:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4391,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.22521,"AVALU":"U/L","BASE2":24.7834,"BASE":38.19333,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.5582,"PCHG2":-46.63684,"CHG":-24.96812,"PCHG":-65.37299,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-11-07 01:03:47","ADY":1055,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-10","SUBJID":"id-10","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.58058,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-17 01:03:47","TRTEDTM":"2023-12-17 19:03:47","TRT01SDTM":"2020-12-17 01:03:47","TRT01EDTM":"2022-12-17 13:03:47","TRT02SDTM":"2022-12-17 13:03:47","TRT02EDTM":"2023-12-17 19:03:47","AP01SDTM":"2020-12-17 01:03:47","AP01EDTM":"2022-12-17 13:03:47","AP02SDTM":"2022-12-17 13:03:47","AP02EDTM":"2023-12-17 19:03:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4261,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.70454,"AVALU":"U/L","BASE2":24.7834,"BASE":38.19333,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.92114,"PCHG2":35.99642,"CHG":-4.48879,"PCHG":-11.7528,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-11-27 01:03:47","ADY":1075,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-10","SUBJID":"id-10","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.58058,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-17 01:03:47","TRTEDTM":"2023-12-17 19:03:47","TRT01SDTM":"2020-12-17 01:03:47","TRT01EDTM":"2022-12-17 13:03:47","TRT02SDTM":"2022-12-17 13:03:47","TRT02EDTM":"2023-12-17 19:03:47","AP01SDTM":"2020-12-17 01:03:47","AP01EDTM":"2022-12-17 13:03:47","AP02SDTM":"2022-12-17 13:03:47","AP02EDTM":"2023-12-17 19:03:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8168,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.63264,"AVALU":"mg/L","BASE2":8.63264,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-01 01:03:47","ADY":531,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-10","SUBJID":"id-10","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.58058,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-17 01:03:47","TRTEDTM":"2023-12-17 19:03:47","TRT01SDTM":"2020-12-17 01:03:47","TRT01EDTM":"2022-12-17 13:03:47","TRT02SDTM":"2022-12-17 13:03:47","TRT02EDTM":"2023-12-17 19:03:47","AP01SDTM":"2020-12-17 01:03:47","AP01EDTM":"2022-12-17 13:03:47","AP02SDTM":"2022-12-17 13:03:47","AP02EDTM":"2023-12-17 19:03:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6960,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.60774,"AVALU":"mg/L","BASE2":8.63264,"BASE":8.60774,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.02489,"PCHG2":-0.28835,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-25 01:03:47","ADY":555,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-10","SUBJID":"id-10","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.58058,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-17 01:03:47","TRTEDTM":"2023-12-17 19:03:47","TRT01SDTM":"2020-12-17 01:03:47","TRT01EDTM":"2022-12-17 13:03:47","TRT02SDTM":"2022-12-17 13:03:47","TRT02EDTM":"2023-12-17 19:03:47","AP01SDTM":"2020-12-17 01:03:47","AP01EDTM":"2022-12-17 13:03:47","AP02SDTM":"2022-12-17 13:03:47","AP02EDTM":"2023-12-17 19:03:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":526,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.79979,"AVALU":"mg/L","BASE2":8.63264,"BASE":8.60774,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.16715,"PCHG2":13.52019,"CHG":1.19204,"PCHG":13.84847,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-28 01:03:47","ADY":558,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-10","SUBJID":"id-10","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.58058,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-17 01:03:47","TRTEDTM":"2023-12-17 19:03:47","TRT01SDTM":"2020-12-17 01:03:47","TRT01EDTM":"2022-12-17 13:03:47","TRT02SDTM":"2022-12-17 13:03:47","TRT02EDTM":"2023-12-17 19:03:47","AP01SDTM":"2020-12-17 01:03:47","AP01EDTM":"2022-12-17 13:03:47","AP02SDTM":"2022-12-17 13:03:47","AP02EDTM":"2023-12-17 19:03:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2658,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.60474,"AVALU":"mg/L","BASE2":8.63264,"BASE":8.60774,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0279,"PCHG2":-0.32319,"CHG":-0.00301,"PCHG":-0.03494,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-06 01:03:47","ADY":628,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-10","SUBJID":"id-10","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.58058,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-17 01:03:47","TRTEDTM":"2023-12-17 19:03:47","TRT01SDTM":"2020-12-17 01:03:47","TRT01EDTM":"2022-12-17 13:03:47","TRT02SDTM":"2022-12-17 13:03:47","TRT02EDTM":"2023-12-17 19:03:47","AP01SDTM":"2020-12-17 01:03:47","AP01EDTM":"2022-12-17 13:03:47","AP02SDTM":"2022-12-17 13:03:47","AP02EDTM":"2023-12-17 19:03:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2921,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.32208,"AVALU":"mg/L","BASE2":8.63264,"BASE":8.60774,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.31055,"PCHG2":-15.18137,"CHG":-1.28566,"PCHG":-14.93609,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2023-01-23 01:03:47","ADY":767,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-10","SUBJID":"id-10","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.58058,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-17 01:03:47","TRTEDTM":"2023-12-17 19:03:47","TRT01SDTM":"2020-12-17 01:03:47","TRT01EDTM":"2022-12-17 13:03:47","TRT02SDTM":"2022-12-17 13:03:47","TRT02EDTM":"2023-12-17 19:03:47","AP01SDTM":"2020-12-17 01:03:47","AP01EDTM":"2022-12-17 13:03:47","AP02SDTM":"2022-12-17 13:03:47","AP02EDTM":"2023-12-17 19:03:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6096,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.45806,"AVALU":"mg/L","BASE2":8.63264,"BASE":8.60774,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17458,"PCHG2":-2.02228,"CHG":-0.14968,"PCHG":-1.73895,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-11-07 01:03:47","ADY":1055,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-10","SUBJID":"id-10","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.58058,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-17 01:03:47","TRTEDTM":"2023-12-17 19:03:47","TRT01SDTM":"2020-12-17 01:03:47","TRT01EDTM":"2022-12-17 13:03:47","TRT02SDTM":"2022-12-17 13:03:47","TRT02EDTM":"2023-12-17 19:03:47","AP01SDTM":"2020-12-17 01:03:47","AP01EDTM":"2022-12-17 13:03:47","AP02SDTM":"2022-12-17 13:03:47","AP02EDTM":"2023-12-17 19:03:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3954,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.64073,"AVALU":"mg/L","BASE2":8.63264,"BASE":8.60774,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.99191,"PCHG2":-11.49019,"CHG":-0.96701,"PCHG":-11.23424,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2023-11-27 01:03:47","ADY":1075,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-10","SUBJID":"id-10","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.58058,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-17 01:03:47","TRTEDTM":"2023-12-17 19:03:47","TRT01SDTM":"2020-12-17 01:03:47","TRT01EDTM":"2022-12-17 13:03:47","TRT02SDTM":"2022-12-17 13:03:47","TRT02EDTM":"2023-12-17 19:03:47","AP01SDTM":"2020-12-17 01:03:47","AP01EDTM":"2022-12-17 13:03:47","AP02SDTM":"2022-12-17 13:03:47","AP02EDTM":"2023-12-17 19:03:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5903,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.73492,"AVALU":"g/L","BASE2":2.73492,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-01 01:03:47","ADY":531,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-10","SUBJID":"id-10","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.58058,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-17 01:03:47","TRTEDTM":"2023-12-17 19:03:47","TRT01SDTM":"2020-12-17 01:03:47","TRT01EDTM":"2022-12-17 13:03:47","TRT02SDTM":"2022-12-17 13:03:47","TRT02EDTM":"2023-12-17 19:03:47","AP01SDTM":"2020-12-17 01:03:47","AP01EDTM":"2022-12-17 13:03:47","AP02SDTM":"2022-12-17 13:03:47","AP02EDTM":"2023-12-17 19:03:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2766,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94046,"AVALU":"g/L","BASE2":2.73492,"BASE":2.94046,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.20554,"PCHG2":7.51543,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-25 01:03:47","ADY":555,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-10","SUBJID":"id-10","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.58058,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-17 01:03:47","TRTEDTM":"2023-12-17 19:03:47","TRT01SDTM":"2020-12-17 01:03:47","TRT01EDTM":"2022-12-17 13:03:47","TRT02SDTM":"2022-12-17 13:03:47","TRT02EDTM":"2023-12-17 19:03:47","AP01SDTM":"2020-12-17 01:03:47","AP01EDTM":"2022-12-17 13:03:47","AP02SDTM":"2022-12-17 13:03:47","AP02EDTM":"2023-12-17 19:03:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1028,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9755,"AVALU":"g/L","BASE2":2.73492,"BASE":2.94046,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.24058,"PCHG2":8.79669,"CHG":0.03504,"PCHG":1.19171,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-28 01:03:47","ADY":558,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-10","SUBJID":"id-10","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.58058,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-17 01:03:47","TRTEDTM":"2023-12-17 19:03:47","TRT01SDTM":"2020-12-17 01:03:47","TRT01EDTM":"2022-12-17 13:03:47","TRT02SDTM":"2022-12-17 13:03:47","TRT02EDTM":"2023-12-17 19:03:47","AP01SDTM":"2020-12-17 01:03:47","AP01EDTM":"2022-12-17 13:03:47","AP02SDTM":"2022-12-17 13:03:47","AP02EDTM":"2023-12-17 19:03:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2926,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98762,"AVALU":"g/L","BASE2":2.73492,"BASE":2.94046,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.2527,"PCHG2":9.23978,"CHG":0.04716,"PCHG":1.60382,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-06 01:03:47","ADY":628,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-10","SUBJID":"id-10","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.58058,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-17 01:03:47","TRTEDTM":"2023-12-17 19:03:47","TRT01SDTM":"2020-12-17 01:03:47","TRT01EDTM":"2022-12-17 13:03:47","TRT02SDTM":"2022-12-17 13:03:47","TRT02EDTM":"2023-12-17 19:03:47","AP01SDTM":"2020-12-17 01:03:47","AP01EDTM":"2022-12-17 13:03:47","AP02SDTM":"2022-12-17 13:03:47","AP02EDTM":"2023-12-17 19:03:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5462,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00881,"AVALU":"g/L","BASE2":2.73492,"BASE":2.94046,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.27389,"PCHG2":10.01466,"CHG":0.06835,"PCHG":2.32453,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2023-01-23 01:03:47","ADY":767,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-10","SUBJID":"id-10","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.58058,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-17 01:03:47","TRTEDTM":"2023-12-17 19:03:47","TRT01SDTM":"2020-12-17 01:03:47","TRT01EDTM":"2022-12-17 13:03:47","TRT02SDTM":"2022-12-17 13:03:47","TRT02EDTM":"2023-12-17 19:03:47","AP01SDTM":"2020-12-17 01:03:47","AP01EDTM":"2022-12-17 13:03:47","AP02SDTM":"2022-12-17 13:03:47","AP02EDTM":"2023-12-17 19:03:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6138,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.09705,"AVALU":"g/L","BASE2":2.73492,"BASE":2.94046,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.36214,"PCHG2":13.2412,"CHG":0.1566,"PCHG":5.32553,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2023-11-07 01:03:47","ADY":1055,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-10","SUBJID":"id-10","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.58058,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-17","TRTSDTM":"2020-12-17 01:03:47","TRTEDTM":"2023-12-17 19:03:47","TRT01SDTM":"2020-12-17 01:03:47","TRT01EDTM":"2022-12-17 13:03:47","TRT02SDTM":"2022-12-17 13:03:47","TRT02EDTM":"2023-12-17 19:03:47","AP01SDTM":"2020-12-17 01:03:47","AP01EDTM":"2022-12-17 13:03:47","AP02SDTM":"2022-12-17 13:03:47","AP02EDTM":"2023-12-17 19:03:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":803,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0179,"AVALU":"g/L","BASE2":2.73492,"BASE":2.94046,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.28299,"PCHG2":10.34712,"CHG":0.07744,"PCHG":2.63375,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2023-11-27 01:03:47","ADY":1075,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-129","SUBJID":"id-129","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.12912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-08","TRTSDTM":"2020-11-11 01:20:00","TRTEDTM":"2023-11-11 19:20:00","TRT01SDTM":"2020-11-11 01:20:00","TRT01EDTM":"2022-11-11 13:20:00","TRT02SDTM":"2022-11-11 13:20:00","TRT02EDTM":"2023-11-11 19:20:00","AP01SDTM":"2020-11-11 01:20:00","AP01EDTM":"2022-11-11 13:20:00","AP02SDTM":"2022-11-11 13:20:00","AP02EDTM":"2023-11-11 19:20:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-11","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5120,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.64889,"AVALU":"U/L","BASE2":4.64889,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-1","ADTM":"2021-04-20 01:20:00","ADY":160,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-129","SUBJID":"id-129","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.12912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-08","TRTSDTM":"2020-11-11 01:20:00","TRTEDTM":"2023-11-11 19:20:00","TRT01SDTM":"2020-11-11 01:20:00","TRT01EDTM":"2022-11-11 13:20:00","TRT02SDTM":"2022-11-11 13:20:00","TRT02EDTM":"2023-11-11 19:20:00","AP01SDTM":"2020-11-11 01:20:00","AP01EDTM":"2022-11-11 13:20:00","AP02SDTM":"2022-11-11 13:20:00","AP02EDTM":"2023-11-11 19:20:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-11","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7023,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.38318,"AVALU":"U/L","BASE2":4.64889,"BASE":3.38318,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.26571,"PCHG2":-27.22612,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2021-12-29 01:20:00","ADY":413,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-129","SUBJID":"id-129","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.12912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-08","TRTSDTM":"2020-11-11 01:20:00","TRTEDTM":"2023-11-11 19:20:00","TRT01SDTM":"2020-11-11 01:20:00","TRT01EDTM":"2022-11-11 13:20:00","TRT02SDTM":"2022-11-11 13:20:00","TRT02EDTM":"2023-11-11 19:20:00","AP01SDTM":"2020-11-11 01:20:00","AP01EDTM":"2022-11-11 13:20:00","AP02SDTM":"2022-11-11 13:20:00","AP02EDTM":"2023-11-11 19:20:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-11","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8096,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.64541,"AVALU":"U/L","BASE2":4.64889,"BASE":3.38318,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.99652,"PCHG2":279.56156,"CHG":14.26223,"PCHG":421.5629,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-07-23 01:20:00","ADY":619,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-129","SUBJID":"id-129","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.12912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-08","TRTSDTM":"2020-11-11 01:20:00","TRTEDTM":"2023-11-11 19:20:00","TRT01SDTM":"2020-11-11 01:20:00","TRT01EDTM":"2022-11-11 13:20:00","TRT02SDTM":"2022-11-11 13:20:00","TRT02EDTM":"2023-11-11 19:20:00","AP01SDTM":"2020-11-11 01:20:00","AP01EDTM":"2022-11-11 13:20:00","AP02SDTM":"2022-11-11 13:20:00","AP02EDTM":"2023-11-11 19:20:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-11","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":405,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.18188,"AVALU":"U/L","BASE2":4.64889,"BASE":3.38318,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.53299,"PCHG2":334.12228,"CHG":16.7987,"PCHG":496.53584,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-07-26 01:20:00","ADY":622,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-129","SUBJID":"id-129","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.12912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-08","TRTSDTM":"2020-11-11 01:20:00","TRTEDTM":"2023-11-11 19:20:00","TRT01SDTM":"2020-11-11 01:20:00","TRT01EDTM":"2022-11-11 13:20:00","TRT02SDTM":"2022-11-11 13:20:00","TRT02EDTM":"2023-11-11 19:20:00","AP01SDTM":"2020-11-11 01:20:00","AP01EDTM":"2022-11-11 13:20:00","AP02SDTM":"2022-11-11 13:20:00","AP02EDTM":"2023-11-11 19:20:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-11","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":246,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.34288,"AVALU":"U/L","BASE2":4.64889,"BASE":3.38318,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.69399,"PCHG2":230.03304,"CHG":11.9597,"PCHG":353.5048,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-09-22 01:20:00","ADY":680,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-129","SUBJID":"id-129","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.12912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-08","TRTSDTM":"2020-11-11 01:20:00","TRTEDTM":"2023-11-11 19:20:00","TRT01SDTM":"2020-11-11 01:20:00","TRT01EDTM":"2022-11-11 13:20:00","TRT02SDTM":"2022-11-11 13:20:00","TRT02EDTM":"2023-11-11 19:20:00","AP01SDTM":"2020-11-11 01:20:00","AP01EDTM":"2022-11-11 13:20:00","AP02SDTM":"2022-11-11 13:20:00","AP02EDTM":"2023-11-11 19:20:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-11","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5114,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.44502,"AVALU":"U/L","BASE2":4.64889,"BASE":3.38318,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":20.79613,"PCHG2":447.33498,"CHG":22.06184,"PCHG":652.10361,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-11-08 01:20:00","ADY":727,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-129","SUBJID":"id-129","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.12912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-08","TRTSDTM":"2020-11-11 01:20:00","TRTEDTM":"2023-11-11 19:20:00","TRT01SDTM":"2020-11-11 01:20:00","TRT01EDTM":"2022-11-11 13:20:00","TRT02SDTM":"2022-11-11 13:20:00","TRT02EDTM":"2023-11-11 19:20:00","AP01SDTM":"2020-11-11 01:20:00","AP01EDTM":"2022-11-11 13:20:00","AP02SDTM":"2022-11-11 13:20:00","AP02EDTM":"2023-11-11 19:20:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-11","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6862,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.57267,"AVALU":"U/L","BASE2":4.64889,"BASE":3.38318,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.92378,"PCHG2":213.46539,"CHG":11.18949,"PCHG":330.73886,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2023-09-19 01:20:00","ADY":1042,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-129","SUBJID":"id-129","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.12912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-08","TRTSDTM":"2020-11-11 01:20:00","TRTEDTM":"2023-11-11 19:20:00","TRT01SDTM":"2020-11-11 01:20:00","TRT01EDTM":"2022-11-11 13:20:00","TRT02SDTM":"2022-11-11 13:20:00","TRT02EDTM":"2023-11-11 19:20:00","AP01SDTM":"2020-11-11 01:20:00","AP01EDTM":"2022-11-11 13:20:00","AP02SDTM":"2022-11-11 13:20:00","AP02EDTM":"2023-11-11 19:20:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-11","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7306,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.25224,"AVALU":"mg/L","BASE2":10.25224,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"","ATOXGR":"1","BTOXGR":"-3","ADTM":"2021-04-20 01:20:00","ADY":160,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-129","SUBJID":"id-129","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.12912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-08","TRTSDTM":"2020-11-11 01:20:00","TRTEDTM":"2023-11-11 19:20:00","TRT01SDTM":"2020-11-11 01:20:00","TRT01EDTM":"2022-11-11 13:20:00","TRT02SDTM":"2022-11-11 13:20:00","TRT02EDTM":"2023-11-11 19:20:00","AP01SDTM":"2020-11-11 01:20:00","AP01EDTM":"2022-11-11 13:20:00","AP02SDTM":"2022-11-11 13:20:00","AP02EDTM":"2023-11-11 19:20:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-11","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7875,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.82757,"AVALU":"mg/L","BASE2":10.25224,"BASE":7.82757,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.42467,"PCHG2":-23.65013,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2021-12-29 01:20:00","ADY":413,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-129","SUBJID":"id-129","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.12912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-08","TRTSDTM":"2020-11-11 01:20:00","TRTEDTM":"2023-11-11 19:20:00","TRT01SDTM":"2020-11-11 01:20:00","TRT01EDTM":"2022-11-11 13:20:00","TRT02SDTM":"2022-11-11 13:20:00","TRT02EDTM":"2023-11-11 19:20:00","AP01SDTM":"2020-11-11 01:20:00","AP01EDTM":"2022-11-11 13:20:00","AP02SDTM":"2022-11-11 13:20:00","AP02EDTM":"2023-11-11 19:20:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-11","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1475,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.16608,"AVALU":"mg/L","BASE2":10.25224,"BASE":7.82757,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.08616,"PCHG2":-20.3483,"CHG":0.33851,"PCHG":4.32461,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2022-07-23 01:20:00","ADY":619,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-129","SUBJID":"id-129","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.12912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-08","TRTSDTM":"2020-11-11 01:20:00","TRTEDTM":"2023-11-11 19:20:00","TRT01SDTM":"2020-11-11 01:20:00","TRT01EDTM":"2022-11-11 13:20:00","TRT02SDTM":"2022-11-11 13:20:00","TRT02EDTM":"2023-11-11 19:20:00","AP01SDTM":"2020-11-11 01:20:00","AP01EDTM":"2022-11-11 13:20:00","AP02SDTM":"2022-11-11 13:20:00","AP02EDTM":"2023-11-11 19:20:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-11","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5411,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.7732,"AVALU":"mg/L","BASE2":10.25224,"BASE":7.82757,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.47904,"PCHG2":-14.42652,"CHG":0.94563,"PCHG":12.08073,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2022-07-26 01:20:00","ADY":622,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-129","SUBJID":"id-129","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.12912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-08","TRTSDTM":"2020-11-11 01:20:00","TRTEDTM":"2023-11-11 19:20:00","TRT01SDTM":"2020-11-11 01:20:00","TRT01EDTM":"2022-11-11 13:20:00","TRT02SDTM":"2022-11-11 13:20:00","TRT02EDTM":"2023-11-11 19:20:00","AP01SDTM":"2020-11-11 01:20:00","AP01EDTM":"2022-11-11 13:20:00","AP02SDTM":"2022-11-11 13:20:00","AP02EDTM":"2023-11-11 19:20:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-11","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4777,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.33115,"AVALU":"mg/L","BASE2":10.25224,"BASE":7.82757,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07891,"PCHG2":0.76965,"CHG":2.50357,"PCHG":31.98405,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"1","BTOXGR":"-3","ADTM":"2022-09-22 01:20:00","ADY":680,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-129","SUBJID":"id-129","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.12912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-08","TRTSDTM":"2020-11-11 01:20:00","TRTEDTM":"2023-11-11 19:20:00","TRT01SDTM":"2020-11-11 01:20:00","TRT01EDTM":"2022-11-11 13:20:00","TRT02SDTM":"2022-11-11 13:20:00","TRT02EDTM":"2023-11-11 19:20:00","AP01SDTM":"2020-11-11 01:20:00","AP01EDTM":"2022-11-11 13:20:00","AP02SDTM":"2022-11-11 13:20:00","AP02EDTM":"2023-11-11 19:20:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-11","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1032,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.61142,"AVALU":"mg/L","BASE2":10.25224,"BASE":7.82757,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.64082,"PCHG2":-16.00454,"CHG":0.78385,"PCHG":10.0139,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2022-11-08 01:20:00","ADY":727,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-129","SUBJID":"id-129","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.12912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-08","TRTSDTM":"2020-11-11 01:20:00","TRTEDTM":"2023-11-11 19:20:00","TRT01SDTM":"2020-11-11 01:20:00","TRT01EDTM":"2022-11-11 13:20:00","TRT02SDTM":"2022-11-11 13:20:00","TRT02EDTM":"2023-11-11 19:20:00","AP01SDTM":"2020-11-11 01:20:00","AP01EDTM":"2022-11-11 13:20:00","AP02SDTM":"2022-11-11 13:20:00","AP02EDTM":"2023-11-11 19:20:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-11","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3452,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.74666,"AVALU":"mg/L","BASE2":10.25224,"BASE":7.82757,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.50558,"PCHG2":-4.93137,"CHG":1.91909,"PCHG":24.5171,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2023-09-19 01:20:00","ADY":1042,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-129","SUBJID":"id-129","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.12912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-08","TRTSDTM":"2020-11-11 01:20:00","TRTEDTM":"2023-11-11 19:20:00","TRT01SDTM":"2020-11-11 01:20:00","TRT01EDTM":"2022-11-11 13:20:00","TRT02SDTM":"2022-11-11 13:20:00","TRT02EDTM":"2023-11-11 19:20:00","AP01SDTM":"2020-11-11 01:20:00","AP01EDTM":"2022-11-11 13:20:00","AP02SDTM":"2022-11-11 13:20:00","AP02EDTM":"2023-11-11 19:20:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-11","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3403,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86966,"AVALU":"g/L","BASE2":2.86966,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-20 01:20:00","ADY":160,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-129","SUBJID":"id-129","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.12912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-08","TRTSDTM":"2020-11-11 01:20:00","TRTEDTM":"2023-11-11 19:20:00","TRT01SDTM":"2020-11-11 01:20:00","TRT01EDTM":"2022-11-11 13:20:00","TRT02SDTM":"2022-11-11 13:20:00","TRT02EDTM":"2023-11-11 19:20:00","AP01SDTM":"2020-11-11 01:20:00","AP01EDTM":"2022-11-11 13:20:00","AP02SDTM":"2022-11-11 13:20:00","AP02EDTM":"2023-11-11 19:20:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-11","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2702,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96583,"AVALU":"g/L","BASE2":2.86966,"BASE":2.96583,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.09617,"PCHG2":3.35127,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-29 01:20:00","ADY":413,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-129","SUBJID":"id-129","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.12912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-08","TRTSDTM":"2020-11-11 01:20:00","TRTEDTM":"2023-11-11 19:20:00","TRT01SDTM":"2020-11-11 01:20:00","TRT01EDTM":"2022-11-11 13:20:00","TRT02SDTM":"2022-11-11 13:20:00","TRT02EDTM":"2023-11-11 19:20:00","AP01SDTM":"2020-11-11 01:20:00","AP01EDTM":"2022-11-11 13:20:00","AP02SDTM":"2022-11-11 13:20:00","AP02EDTM":"2023-11-11 19:20:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-11","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1648,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91611,"AVALU":"g/L","BASE2":2.86966,"BASE":2.96583,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04645,"PCHG2":1.61873,"CHG":-0.04972,"PCHG":-1.67636,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-23 01:20:00","ADY":619,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-129","SUBJID":"id-129","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.12912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-08","TRTSDTM":"2020-11-11 01:20:00","TRTEDTM":"2023-11-11 19:20:00","TRT01SDTM":"2020-11-11 01:20:00","TRT01EDTM":"2022-11-11 13:20:00","TRT02SDTM":"2022-11-11 13:20:00","TRT02EDTM":"2023-11-11 19:20:00","AP01SDTM":"2020-11-11 01:20:00","AP01EDTM":"2022-11-11 13:20:00","AP02SDTM":"2022-11-11 13:20:00","AP02EDTM":"2023-11-11 19:20:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-11","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":193,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85429,"AVALU":"g/L","BASE2":2.86966,"BASE":2.96583,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01537,"PCHG2":-0.5357,"CHG":-0.11154,"PCHG":-3.76094,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-26 01:20:00","ADY":622,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-129","SUBJID":"id-129","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.12912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-08","TRTSDTM":"2020-11-11 01:20:00","TRTEDTM":"2023-11-11 19:20:00","TRT01SDTM":"2020-11-11 01:20:00","TRT01EDTM":"2022-11-11 13:20:00","TRT02SDTM":"2022-11-11 13:20:00","TRT02EDTM":"2023-11-11 19:20:00","AP01SDTM":"2020-11-11 01:20:00","AP01EDTM":"2022-11-11 13:20:00","AP02SDTM":"2022-11-11 13:20:00","AP02EDTM":"2023-11-11 19:20:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-11","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4825,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94212,"AVALU":"g/L","BASE2":2.86966,"BASE":2.96583,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07246,"PCHG2":2.52509,"CHG":-0.02371,"PCHG":-0.7994,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-22 01:20:00","ADY":680,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-129","SUBJID":"id-129","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.12912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-08","TRTSDTM":"2020-11-11 01:20:00","TRTEDTM":"2023-11-11 19:20:00","TRT01SDTM":"2020-11-11 01:20:00","TRT01EDTM":"2022-11-11 13:20:00","TRT02SDTM":"2022-11-11 13:20:00","TRT02EDTM":"2023-11-11 19:20:00","AP01SDTM":"2020-11-11 01:20:00","AP01EDTM":"2022-11-11 13:20:00","AP02SDTM":"2022-11-11 13:20:00","AP02EDTM":"2023-11-11 19:20:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-11","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4184,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85923,"AVALU":"g/L","BASE2":2.86966,"BASE":2.96583,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01043,"PCHG2":-0.36329,"CHG":-0.1066,"PCHG":-3.59411,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-08 01:20:00","ADY":727,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-129","SUBJID":"id-129","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.12912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-08","TRTSDTM":"2020-11-11 01:20:00","TRTEDTM":"2023-11-11 19:20:00","TRT01SDTM":"2020-11-11 01:20:00","TRT01EDTM":"2022-11-11 13:20:00","TRT02SDTM":"2022-11-11 13:20:00","TRT02EDTM":"2023-11-11 19:20:00","AP01SDTM":"2020-11-11 01:20:00","AP01EDTM":"2022-11-11 13:20:00","AP02SDTM":"2022-11-11 13:20:00","AP02EDTM":"2023-11-11 19:20:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-11","EOSDY":1096,"LSTALVDT":"2023-11-22","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6423,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79053,"AVALU":"g/L","BASE2":2.86966,"BASE":2.96583,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07913,"PCHG2":-2.75748,"CHG":-0.1753,"PCHG":-5.91067,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-19 01:20:00","ADY":1042,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-182","SUBJID":"id-182","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.65524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-17","TRTSDTM":"2019-09-18 07:56:08","TRTEDTM":"2022-02-12 09:08:24","TRT01SDTM":"2019-09-18 07:56:08","TRT01EDTM":"2021-02-12 03:08:24","TRT02SDTM":"2021-02-12 03:08:24","TRT02EDTM":"2022-02-12 09:08:24","AP01SDTM":"2019-09-18 07:56:08","AP01EDTM":"2021-02-12 03:08:24","AP02SDTM":"2021-02-12 03:08:24","AP02EDTM":"2022-02-12 09:08:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":879,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":902,"ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":704,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.42116,"AVALU":"U/L","BASE2":18.42116,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-26 07:56:08","ADY":8,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-182","SUBJID":"id-182","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.65524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-17","TRTSDTM":"2019-09-18 07:56:08","TRTEDTM":"2022-02-12 09:08:24","TRT01SDTM":"2019-09-18 07:56:08","TRT01EDTM":"2021-02-12 03:08:24","TRT02SDTM":"2021-02-12 03:08:24","TRT02EDTM":"2022-02-12 09:08:24","AP01SDTM":"2019-09-18 07:56:08","AP01EDTM":"2021-02-12 03:08:24","AP02SDTM":"2021-02-12 03:08:24","AP02EDTM":"2022-02-12 09:08:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":879,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":902,"ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2517,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.16167,"AVALU":"U/L","BASE2":18.42116,"BASE":31.16167,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":12.74051,"PCHG2":69.16239,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-17 07:56:08","ADY":121,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-182","SUBJID":"id-182","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.65524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-17","TRTSDTM":"2019-09-18 07:56:08","TRTEDTM":"2022-02-12 09:08:24","TRT01SDTM":"2019-09-18 07:56:08","TRT01EDTM":"2021-02-12 03:08:24","TRT02SDTM":"2021-02-12 03:08:24","TRT02EDTM":"2022-02-12 09:08:24","AP01SDTM":"2019-09-18 07:56:08","AP01EDTM":"2021-02-12 03:08:24","AP02SDTM":"2021-02-12 03:08:24","AP02EDTM":"2022-02-12 09:08:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":879,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":902,"ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6415,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.21959,"AVALU":"U/L","BASE2":18.42116,"BASE":31.16167,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.20157,"PCHG2":-39.09399,"CHG":-19.94208,"PCHG":-63.99553,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-20 07:56:08","ADY":490,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-182","SUBJID":"id-182","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.65524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-17","TRTSDTM":"2019-09-18 07:56:08","TRTEDTM":"2022-02-12 09:08:24","TRT01SDTM":"2019-09-18 07:56:08","TRT01EDTM":"2021-02-12 03:08:24","TRT02SDTM":"2021-02-12 03:08:24","TRT02EDTM":"2022-02-12 09:08:24","AP01SDTM":"2019-09-18 07:56:08","AP01EDTM":"2021-02-12 03:08:24","AP02SDTM":"2021-02-12 03:08:24","AP02EDTM":"2022-02-12 09:08:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":879,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":902,"ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7175,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.1563,"AVALU":"U/L","BASE2":18.42116,"BASE":31.16167,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-15.26486,"PCHG2":-82.8659,"CHG":-28.00537,"PCHG":-89.87121,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-02-21 07:56:08","ADY":522,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-182","SUBJID":"id-182","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.65524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-17","TRTSDTM":"2019-09-18 07:56:08","TRTEDTM":"2022-02-12 09:08:24","TRT01SDTM":"2019-09-18 07:56:08","TRT01EDTM":"2021-02-12 03:08:24","TRT02SDTM":"2021-02-12 03:08:24","TRT02EDTM":"2022-02-12 09:08:24","AP01SDTM":"2019-09-18 07:56:08","AP01EDTM":"2021-02-12 03:08:24","AP02SDTM":"2021-02-12 03:08:24","AP02EDTM":"2022-02-12 09:08:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":879,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":902,"ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4068,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.38437,"AVALU":"U/L","BASE2":18.42116,"BASE":31.16167,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.03679,"PCHG2":-38.19951,"CHG":-19.77731,"PCHG":-63.46677,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-23 07:56:08","ADY":552,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-182","SUBJID":"id-182","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.65524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-17","TRTSDTM":"2019-09-18 07:56:08","TRTEDTM":"2022-02-12 09:08:24","TRT01SDTM":"2019-09-18 07:56:08","TRT01EDTM":"2021-02-12 03:08:24","TRT02SDTM":"2021-02-12 03:08:24","TRT02EDTM":"2022-02-12 09:08:24","AP01SDTM":"2019-09-18 07:56:08","AP01EDTM":"2021-02-12 03:08:24","AP02SDTM":"2021-02-12 03:08:24","AP02EDTM":"2022-02-12 09:08:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":879,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":902,"ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1504,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":38.21755,"AVALU":"U/L","BASE2":18.42116,"BASE":31.16167,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.79639,"PCHG2":107.46551,"CHG":7.05588,"PCHG":22.64281,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-14 07:56:08","ADY":788,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-182","SUBJID":"id-182","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.65524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-17","TRTSDTM":"2019-09-18 07:56:08","TRTEDTM":"2022-02-12 09:08:24","TRT01SDTM":"2019-09-18 07:56:08","TRT01EDTM":"2021-02-12 03:08:24","TRT02SDTM":"2021-02-12 03:08:24","TRT02EDTM":"2022-02-12 09:08:24","AP01SDTM":"2019-09-18 07:56:08","AP01EDTM":"2021-02-12 03:08:24","AP02SDTM":"2021-02-12 03:08:24","AP02EDTM":"2022-02-12 09:08:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":879,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":902,"ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3297,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":35.00258,"AVALU":"U/L","BASE2":18.42116,"BASE":31.16167,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.58142,"PCHG2":90.01291,"CHG":3.84091,"PCHG":12.32575,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-26 07:56:08","ADY":830,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-182","SUBJID":"id-182","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.65524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-17","TRTSDTM":"2019-09-18 07:56:08","TRTEDTM":"2022-02-12 09:08:24","TRT01SDTM":"2019-09-18 07:56:08","TRT01EDTM":"2021-02-12 03:08:24","TRT02SDTM":"2021-02-12 03:08:24","TRT02EDTM":"2022-02-12 09:08:24","AP01SDTM":"2019-09-18 07:56:08","AP01EDTM":"2021-02-12 03:08:24","AP02SDTM":"2021-02-12 03:08:24","AP02EDTM":"2022-02-12 09:08:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":879,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":902,"ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7339,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.1204,"AVALU":"mg/L","BASE2":9.1204,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2019-09-26 07:56:08","ADY":8,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-182","SUBJID":"id-182","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.65524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-17","TRTSDTM":"2019-09-18 07:56:08","TRTEDTM":"2022-02-12 09:08:24","TRT01SDTM":"2019-09-18 07:56:08","TRT01EDTM":"2021-02-12 03:08:24","TRT02SDTM":"2021-02-12 03:08:24","TRT02EDTM":"2022-02-12 09:08:24","AP01SDTM":"2019-09-18 07:56:08","AP01EDTM":"2021-02-12 03:08:24","AP02SDTM":"2021-02-12 03:08:24","AP02EDTM":"2022-02-12 09:08:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":879,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":902,"ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4139,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.29499,"AVALU":"mg/L","BASE2":9.1204,"BASE":10.29499,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.17459,"PCHG2":12.87869,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-01-17 07:56:08","ADY":121,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-182","SUBJID":"id-182","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.65524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-17","TRTSDTM":"2019-09-18 07:56:08","TRTEDTM":"2022-02-12 09:08:24","TRT01SDTM":"2019-09-18 07:56:08","TRT01EDTM":"2021-02-12 03:08:24","TRT02SDTM":"2021-02-12 03:08:24","TRT02EDTM":"2022-02-12 09:08:24","AP01SDTM":"2019-09-18 07:56:08","AP01EDTM":"2021-02-12 03:08:24","AP02SDTM":"2021-02-12 03:08:24","AP02EDTM":"2022-02-12 09:08:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":879,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":902,"ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4149,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.55038,"AVALU":"mg/L","BASE2":9.1204,"BASE":10.29499,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.42998,"PCHG2":4.71446,"CHG":-0.74461,"PCHG":-7.23275,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-01-20 07:56:08","ADY":490,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-182","SUBJID":"id-182","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.65524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-17","TRTSDTM":"2019-09-18 07:56:08","TRTEDTM":"2022-02-12 09:08:24","TRT01SDTM":"2019-09-18 07:56:08","TRT01EDTM":"2021-02-12 03:08:24","TRT02SDTM":"2021-02-12 03:08:24","TRT02EDTM":"2022-02-12 09:08:24","AP01SDTM":"2019-09-18 07:56:08","AP01EDTM":"2021-02-12 03:08:24","AP02SDTM":"2021-02-12 03:08:24","AP02EDTM":"2022-02-12 09:08:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":879,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":902,"ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4848,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.39246,"AVALU":"mg/L","BASE2":9.1204,"BASE":10.29499,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.72794,"PCHG2":-7.98146,"CHG":-1.90253,"PCHG":-18.48014,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-02-21 07:56:08","ADY":522,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-182","SUBJID":"id-182","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.65524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-17","TRTSDTM":"2019-09-18 07:56:08","TRTEDTM":"2022-02-12 09:08:24","TRT01SDTM":"2019-09-18 07:56:08","TRT01EDTM":"2021-02-12 03:08:24","TRT02SDTM":"2021-02-12 03:08:24","TRT02EDTM":"2022-02-12 09:08:24","AP01SDTM":"2019-09-18 07:56:08","AP01EDTM":"2021-02-12 03:08:24","AP02SDTM":"2021-02-12 03:08:24","AP02EDTM":"2022-02-12 09:08:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":879,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":902,"ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1213,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.69415,"AVALU":"mg/L","BASE2":9.1204,"BASE":10.29499,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.57376,"PCHG2":6.29091,"CHG":-0.60083,"PCHG":-5.83616,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-03-23 07:56:08","ADY":552,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-182","SUBJID":"id-182","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.65524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-17","TRTSDTM":"2019-09-18 07:56:08","TRTEDTM":"2022-02-12 09:08:24","TRT01SDTM":"2019-09-18 07:56:08","TRT01EDTM":"2021-02-12 03:08:24","TRT02SDTM":"2021-02-12 03:08:24","TRT02EDTM":"2022-02-12 09:08:24","AP01SDTM":"2019-09-18 07:56:08","AP01EDTM":"2021-02-12 03:08:24","AP02SDTM":"2021-02-12 03:08:24","AP02EDTM":"2022-02-12 09:08:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":879,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":902,"ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6277,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.71948,"AVALU":"mg/L","BASE2":9.1204,"BASE":10.29499,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.40092,"PCHG2":-4.39585,"CHG":-1.57551,"PCHG":-15.30363,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-11-14 07:56:08","ADY":788,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-182","SUBJID":"id-182","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.65524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-17","TRTSDTM":"2019-09-18 07:56:08","TRTEDTM":"2022-02-12 09:08:24","TRT01SDTM":"2019-09-18 07:56:08","TRT01EDTM":"2021-02-12 03:08:24","TRT02SDTM":"2021-02-12 03:08:24","TRT02EDTM":"2022-02-12 09:08:24","AP01SDTM":"2019-09-18 07:56:08","AP01EDTM":"2021-02-12 03:08:24","AP02SDTM":"2021-02-12 03:08:24","AP02EDTM":"2022-02-12 09:08:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":879,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":902,"ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4589,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.81037,"AVALU":"mg/L","BASE2":9.1204,"BASE":10.29499,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.31003,"PCHG2":-3.39932,"CHG":-1.48462,"PCHG":-14.4208,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-12-26 07:56:08","ADY":830,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-182","SUBJID":"id-182","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.65524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-17","TRTSDTM":"2019-09-18 07:56:08","TRTEDTM":"2022-02-12 09:08:24","TRT01SDTM":"2019-09-18 07:56:08","TRT01EDTM":"2021-02-12 03:08:24","TRT02SDTM":"2021-02-12 03:08:24","TRT02EDTM":"2022-02-12 09:08:24","AP01SDTM":"2019-09-18 07:56:08","AP01EDTM":"2021-02-12 03:08:24","AP02SDTM":"2021-02-12 03:08:24","AP02EDTM":"2022-02-12 09:08:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":879,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":902,"ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5137,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01218,"AVALU":"g/L","BASE2":3.01218,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"3","BTOXGR":"0","ADTM":"2019-09-26 07:56:08","ADY":8,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-182","SUBJID":"id-182","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.65524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-17","TRTSDTM":"2019-09-18 07:56:08","TRTEDTM":"2022-02-12 09:08:24","TRT01SDTM":"2019-09-18 07:56:08","TRT01EDTM":"2021-02-12 03:08:24","TRT02SDTM":"2021-02-12 03:08:24","TRT02EDTM":"2022-02-12 09:08:24","AP01SDTM":"2019-09-18 07:56:08","AP01EDTM":"2021-02-12 03:08:24","AP02SDTM":"2021-02-12 03:08:24","AP02EDTM":"2022-02-12 09:08:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":879,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":902,"ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2820,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81428,"AVALU":"g/L","BASE2":3.01218,"BASE":2.81428,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.19789,"PCHG2":-6.56982,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-17 07:56:08","ADY":121,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-182","SUBJID":"id-182","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.65524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-17","TRTSDTM":"2019-09-18 07:56:08","TRTEDTM":"2022-02-12 09:08:24","TRT01SDTM":"2019-09-18 07:56:08","TRT01EDTM":"2021-02-12 03:08:24","TRT02SDTM":"2021-02-12 03:08:24","TRT02EDTM":"2022-02-12 09:08:24","AP01SDTM":"2019-09-18 07:56:08","AP01EDTM":"2021-02-12 03:08:24","AP02SDTM":"2021-02-12 03:08:24","AP02EDTM":"2022-02-12 09:08:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":879,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":902,"ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3159,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9822,"AVALU":"g/L","BASE2":3.01218,"BASE":2.81428,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02998,"PCHG2":-0.99531,"CHG":0.16791,"PCHG":5.96649,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-20 07:56:08","ADY":490,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-182","SUBJID":"id-182","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.65524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-17","TRTSDTM":"2019-09-18 07:56:08","TRTEDTM":"2022-02-12 09:08:24","TRT01SDTM":"2019-09-18 07:56:08","TRT01EDTM":"2021-02-12 03:08:24","TRT02SDTM":"2021-02-12 03:08:24","TRT02EDTM":"2022-02-12 09:08:24","AP01SDTM":"2019-09-18 07:56:08","AP01EDTM":"2021-02-12 03:08:24","AP02SDTM":"2021-02-12 03:08:24","AP02EDTM":"2022-02-12 09:08:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":879,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":902,"ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1536,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96267,"AVALU":"g/L","BASE2":3.01218,"BASE":2.81428,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04951,"PCHG2":-1.64365,"CHG":0.14838,"PCHG":5.27256,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-21 07:56:08","ADY":522,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-182","SUBJID":"id-182","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.65524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-17","TRTSDTM":"2019-09-18 07:56:08","TRTEDTM":"2022-02-12 09:08:24","TRT01SDTM":"2019-09-18 07:56:08","TRT01EDTM":"2021-02-12 03:08:24","TRT02SDTM":"2021-02-12 03:08:24","TRT02EDTM":"2022-02-12 09:08:24","AP01SDTM":"2019-09-18 07:56:08","AP01EDTM":"2021-02-12 03:08:24","AP02SDTM":"2021-02-12 03:08:24","AP02EDTM":"2022-02-12 09:08:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":879,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":902,"ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6231,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85089,"AVALU":"g/L","BASE2":3.01218,"BASE":2.81428,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16129,"PCHG2":-5.35463,"CHG":0.0366,"PCHG":1.30064,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-23 07:56:08","ADY":552,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-182","SUBJID":"id-182","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.65524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-17","TRTSDTM":"2019-09-18 07:56:08","TRTEDTM":"2022-02-12 09:08:24","TRT01SDTM":"2019-09-18 07:56:08","TRT01EDTM":"2021-02-12 03:08:24","TRT02SDTM":"2021-02-12 03:08:24","TRT02EDTM":"2022-02-12 09:08:24","AP01SDTM":"2019-09-18 07:56:08","AP01EDTM":"2021-02-12 03:08:24","AP02SDTM":"2021-02-12 03:08:24","AP02EDTM":"2022-02-12 09:08:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":879,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":902,"ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2685,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81559,"AVALU":"g/L","BASE2":3.01218,"BASE":2.81428,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19659,"PCHG2":-6.52643,"CHG":0.00131,"PCHG":0.04645,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-14 07:56:08","ADY":788,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-182","SUBJID":"id-182","SITEID":"CHN-17","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.65524,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-17","TRTSDTM":"2019-09-18 07:56:08","TRTEDTM":"2022-02-12 09:08:24","TRT01SDTM":"2019-09-18 07:56:08","TRT01EDTM":"2021-02-12 03:08:24","TRT02SDTM":"2021-02-12 03:08:24","TRT02EDTM":"2022-02-12 09:08:24","AP01SDTM":"2019-09-18 07:56:08","AP01EDTM":"2021-02-12 03:08:24","AP02SDTM":"2021-02-12 03:08:24","AP02EDTM":"2022-02-12 09:08:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":879,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":902,"ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2553,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74173,"AVALU":"g/L","BASE2":3.01218,"BASE":2.81428,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.27045,"PCHG2":-8.97853,"CHG":-0.07255,"PCHG":-2.57808,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-26 07:56:08","ADY":830,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-209","SUBJID":"id-209","SITEID":"CHN-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.64011,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-14","TRTSDTM":"2020-12-16 11:13:33","TRTEDTM":"2023-12-17 05:13:33","TRT01SDTM":"2020-12-16 11:13:33","TRT01EDTM":"2022-12-16 23:13:33","TRT02SDTM":"2022-12-16 23:13:33","TRT02EDTM":"2023-12-17 05:13:33","AP01SDTM":"2020-12-16 11:13:33","AP01EDTM":"2022-12-16 23:13:33","AP02SDTM":"2022-12-16 23:13:33","AP02EDTM":"2023-12-17 05:13:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2900,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.12218,"AVALU":"U/L","BASE2":24.12218,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-04-05 11:13:33","ADY":475,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-209","SUBJID":"id-209","SITEID":"CHN-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.64011,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-14","TRTSDTM":"2020-12-16 11:13:33","TRTEDTM":"2023-12-17 05:13:33","TRT01SDTM":"2020-12-16 11:13:33","TRT01EDTM":"2022-12-16 23:13:33","TRT02SDTM":"2022-12-16 23:13:33","TRT02EDTM":"2023-12-17 05:13:33","AP01SDTM":"2020-12-16 11:13:33","AP01EDTM":"2022-12-16 23:13:33","AP02SDTM":"2022-12-16 23:13:33","AP02EDTM":"2023-12-17 05:13:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4446,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.19261,"AVALU":"U/L","BASE2":24.12218,"BASE":1.19261,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-22.92957,"PCHG2":-95.05596,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2022-11-04 11:13:33","ADY":688,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-209","SUBJID":"id-209","SITEID":"CHN-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.64011,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-14","TRTSDTM":"2020-12-16 11:13:33","TRTEDTM":"2023-12-17 05:13:33","TRT01SDTM":"2020-12-16 11:13:33","TRT01EDTM":"2022-12-16 23:13:33","TRT02SDTM":"2022-12-16 23:13:33","TRT02EDTM":"2023-12-17 05:13:33","AP01SDTM":"2020-12-16 11:13:33","AP01EDTM":"2022-12-16 23:13:33","AP02SDTM":"2022-12-16 23:13:33","AP02EDTM":"2023-12-17 05:13:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2129,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.92928,"AVALU":"U/L","BASE2":24.12218,"BASE":1.19261,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.19291,"PCHG2":-50.54644,"CHG":10.73667,"PCHG":900.26525,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2023-01-18 11:13:33","ADY":763,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-209","SUBJID":"id-209","SITEID":"CHN-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.64011,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-14","TRTSDTM":"2020-12-16 11:13:33","TRTEDTM":"2023-12-17 05:13:33","TRT01SDTM":"2020-12-16 11:13:33","TRT01EDTM":"2022-12-16 23:13:33","TRT02SDTM":"2022-12-16 23:13:33","TRT02EDTM":"2023-12-17 05:13:33","AP01SDTM":"2020-12-16 11:13:33","AP01EDTM":"2022-12-16 23:13:33","AP02SDTM":"2022-12-16 23:13:33","AP02EDTM":"2023-12-17 05:13:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":629,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":41.74344,"AVALU":"U/L","BASE2":24.12218,"BASE":1.19261,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":17.62126,"PCHG2":73.05002,"CHG":40.55083,"PCHG":3400.17142,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2023-02-05 11:13:33","ADY":781,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-209","SUBJID":"id-209","SITEID":"CHN-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.64011,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-14","TRTSDTM":"2020-12-16 11:13:33","TRTEDTM":"2023-12-17 05:13:33","TRT01SDTM":"2020-12-16 11:13:33","TRT01EDTM":"2022-12-16 23:13:33","TRT02SDTM":"2022-12-16 23:13:33","TRT02EDTM":"2023-12-17 05:13:33","AP01SDTM":"2020-12-16 11:13:33","AP01EDTM":"2022-12-16 23:13:33","AP02SDTM":"2022-12-16 23:13:33","AP02EDTM":"2023-12-17 05:13:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2905,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.53841,"AVALU":"U/L","BASE2":24.12218,"BASE":1.19261,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.58377,"PCHG2":-31.439,"CHG":15.3458,"PCHG":1286.73934,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2023-04-27 11:13:33","ADY":862,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-209","SUBJID":"id-209","SITEID":"CHN-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.64011,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-14","TRTSDTM":"2020-12-16 11:13:33","TRTEDTM":"2023-12-17 05:13:33","TRT01SDTM":"2020-12-16 11:13:33","TRT01EDTM":"2022-12-16 23:13:33","TRT02SDTM":"2022-12-16 23:13:33","TRT02EDTM":"2023-12-17 05:13:33","AP01SDTM":"2020-12-16 11:13:33","AP01EDTM":"2022-12-16 23:13:33","AP02SDTM":"2022-12-16 23:13:33","AP02EDTM":"2023-12-17 05:13:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5094,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.95938,"AVALU":"U/L","BASE2":24.12218,"BASE":1.19261,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.1628,"PCHG2":-4.82047,"CHG":21.76677,"PCHG":1825.13503,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2023-06-05 11:13:33","ADY":901,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-209","SUBJID":"id-209","SITEID":"CHN-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.64011,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-14","TRTSDTM":"2020-12-16 11:13:33","TRTEDTM":"2023-12-17 05:13:33","TRT01SDTM":"2020-12-16 11:13:33","TRT01EDTM":"2022-12-16 23:13:33","TRT02SDTM":"2022-12-16 23:13:33","TRT02EDTM":"2023-12-17 05:13:33","AP01SDTM":"2020-12-16 11:13:33","AP01EDTM":"2022-12-16 23:13:33","AP02SDTM":"2022-12-16 23:13:33","AP02EDTM":"2023-12-17 05:13:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6753,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.93891,"AVALU":"U/L","BASE2":24.12218,"BASE":1.19261,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.18327,"PCHG2":-4.90531,"CHG":21.7463,"PCHG":1823.4191,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2023-06-14 11:13:33","ADY":910,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-209","SUBJID":"id-209","SITEID":"CHN-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.64011,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-14","TRTSDTM":"2020-12-16 11:13:33","TRTEDTM":"2023-12-17 05:13:33","TRT01SDTM":"2020-12-16 11:13:33","TRT01EDTM":"2022-12-16 23:13:33","TRT02SDTM":"2022-12-16 23:13:33","TRT02EDTM":"2023-12-17 05:13:33","AP01SDTM":"2020-12-16 11:13:33","AP01EDTM":"2022-12-16 23:13:33","AP02SDTM":"2022-12-16 23:13:33","AP02EDTM":"2023-12-17 05:13:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5870,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.74591,"AVALU":"mg/L","BASE2":9.74591,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-05 11:13:33","ADY":475,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-209","SUBJID":"id-209","SITEID":"CHN-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.64011,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-14","TRTSDTM":"2020-12-16 11:13:33","TRTEDTM":"2023-12-17 05:13:33","TRT01SDTM":"2020-12-16 11:13:33","TRT01EDTM":"2022-12-16 23:13:33","TRT02SDTM":"2022-12-16 23:13:33","TRT02EDTM":"2023-12-17 05:13:33","AP01SDTM":"2020-12-16 11:13:33","AP01EDTM":"2022-12-16 23:13:33","AP02SDTM":"2022-12-16 23:13:33","AP02EDTM":"2023-12-17 05:13:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5584,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.87971,"AVALU":"mg/L","BASE2":9.74591,"BASE":9.87971,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.1338,"PCHG2":1.37287,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-04 11:13:33","ADY":688,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-209","SUBJID":"id-209","SITEID":"CHN-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.64011,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-14","TRTSDTM":"2020-12-16 11:13:33","TRTEDTM":"2023-12-17 05:13:33","TRT01SDTM":"2020-12-16 11:13:33","TRT01EDTM":"2022-12-16 23:13:33","TRT02SDTM":"2022-12-16 23:13:33","TRT02EDTM":"2023-12-17 05:13:33","AP01SDTM":"2020-12-16 11:13:33","AP01EDTM":"2022-12-16 23:13:33","AP02SDTM":"2022-12-16 23:13:33","AP02EDTM":"2023-12-17 05:13:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":205,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.94431,"AVALU":"mg/L","BASE2":9.74591,"BASE":9.87971,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.8016,"PCHG2":-8.22499,"CHG":-0.9354,"PCHG":-9.46788,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-18 11:13:33","ADY":763,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-209","SUBJID":"id-209","SITEID":"CHN-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.64011,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-14","TRTSDTM":"2020-12-16 11:13:33","TRTEDTM":"2023-12-17 05:13:33","TRT01SDTM":"2020-12-16 11:13:33","TRT01EDTM":"2022-12-16 23:13:33","TRT02SDTM":"2022-12-16 23:13:33","TRT02EDTM":"2023-12-17 05:13:33","AP01SDTM":"2020-12-16 11:13:33","AP01EDTM":"2022-12-16 23:13:33","AP02SDTM":"2022-12-16 23:13:33","AP02EDTM":"2023-12-17 05:13:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2919,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.28232,"AVALU":"mg/L","BASE2":9.74591,"BASE":9.87971,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.46359,"PCHG2":-4.75674,"CHG":-0.59739,"PCHG":-6.04659,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-05 11:13:33","ADY":781,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-209","SUBJID":"id-209","SITEID":"CHN-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.64011,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-14","TRTSDTM":"2020-12-16 11:13:33","TRTEDTM":"2023-12-17 05:13:33","TRT01SDTM":"2020-12-16 11:13:33","TRT01EDTM":"2022-12-16 23:13:33","TRT02SDTM":"2022-12-16 23:13:33","TRT02EDTM":"2023-12-17 05:13:33","AP01SDTM":"2020-12-16 11:13:33","AP01EDTM":"2022-12-16 23:13:33","AP02SDTM":"2022-12-16 23:13:33","AP02EDTM":"2023-12-17 05:13:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2564,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.21189,"AVALU":"mg/L","BASE2":9.74591,"BASE":9.87971,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.53402,"PCHG2":-5.4794,"CHG":-0.66782,"PCHG":-6.75946,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-27 11:13:33","ADY":862,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-209","SUBJID":"id-209","SITEID":"CHN-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.64011,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-14","TRTSDTM":"2020-12-16 11:13:33","TRTEDTM":"2023-12-17 05:13:33","TRT01SDTM":"2020-12-16 11:13:33","TRT01EDTM":"2022-12-16 23:13:33","TRT02SDTM":"2022-12-16 23:13:33","TRT02EDTM":"2023-12-17 05:13:33","AP01SDTM":"2020-12-16 11:13:33","AP01EDTM":"2022-12-16 23:13:33","AP02SDTM":"2022-12-16 23:13:33","AP02EDTM":"2023-12-17 05:13:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6340,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.70035,"AVALU":"mg/L","BASE2":9.74591,"BASE":9.87971,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.04556,"PCHG2":-10.72817,"CHG":-1.17936,"PCHG":-11.93716,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-05 11:13:33","ADY":901,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-209","SUBJID":"id-209","SITEID":"CHN-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.64011,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-14","TRTSDTM":"2020-12-16 11:13:33","TRTEDTM":"2023-12-17 05:13:33","TRT01SDTM":"2020-12-16 11:13:33","TRT01EDTM":"2022-12-16 23:13:33","TRT02SDTM":"2022-12-16 23:13:33","TRT02EDTM":"2023-12-17 05:13:33","AP01SDTM":"2020-12-16 11:13:33","AP01EDTM":"2022-12-16 23:13:33","AP02SDTM":"2022-12-16 23:13:33","AP02EDTM":"2023-12-17 05:13:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6703,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.81982,"AVALU":"mg/L","BASE2":9.74591,"BASE":9.87971,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.92609,"PCHG2":-9.50237,"CHG":-1.05989,"PCHG":-10.72796,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-14 11:13:33","ADY":910,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-209","SUBJID":"id-209","SITEID":"CHN-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.64011,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-14","TRTSDTM":"2020-12-16 11:13:33","TRTEDTM":"2023-12-17 05:13:33","TRT01SDTM":"2020-12-16 11:13:33","TRT01EDTM":"2022-12-16 23:13:33","TRT02SDTM":"2022-12-16 23:13:33","TRT02EDTM":"2023-12-17 05:13:33","AP01SDTM":"2020-12-16 11:13:33","AP01EDTM":"2022-12-16 23:13:33","AP02SDTM":"2022-12-16 23:13:33","AP02EDTM":"2023-12-17 05:13:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4874,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89249,"AVALU":"g/L","BASE2":2.89249,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-05 11:13:33","ADY":475,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-209","SUBJID":"id-209","SITEID":"CHN-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.64011,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-14","TRTSDTM":"2020-12-16 11:13:33","TRTEDTM":"2023-12-17 05:13:33","TRT01SDTM":"2020-12-16 11:13:33","TRT01EDTM":"2022-12-16 23:13:33","TRT02SDTM":"2022-12-16 23:13:33","TRT02EDTM":"2023-12-17 05:13:33","AP01SDTM":"2020-12-16 11:13:33","AP01EDTM":"2022-12-16 23:13:33","AP02SDTM":"2022-12-16 23:13:33","AP02EDTM":"2023-12-17 05:13:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3817,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88598,"AVALU":"g/L","BASE2":2.89249,"BASE":2.88598,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.00651,"PCHG2":-0.22513,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-04 11:13:33","ADY":688,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-209","SUBJID":"id-209","SITEID":"CHN-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.64011,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-14","TRTSDTM":"2020-12-16 11:13:33","TRTEDTM":"2023-12-17 05:13:33","TRT01SDTM":"2020-12-16 11:13:33","TRT01EDTM":"2022-12-16 23:13:33","TRT02SDTM":"2022-12-16 23:13:33","TRT02EDTM":"2023-12-17 05:13:33","AP01SDTM":"2020-12-16 11:13:33","AP01EDTM":"2022-12-16 23:13:33","AP02SDTM":"2022-12-16 23:13:33","AP02EDTM":"2023-12-17 05:13:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4801,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94684,"AVALU":"g/L","BASE2":2.89249,"BASE":2.88598,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05434,"PCHG2":1.87868,"CHG":0.06085,"PCHG":2.10855,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-18 11:13:33","ADY":763,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-209","SUBJID":"id-209","SITEID":"CHN-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.64011,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-14","TRTSDTM":"2020-12-16 11:13:33","TRTEDTM":"2023-12-17 05:13:33","TRT01SDTM":"2020-12-16 11:13:33","TRT01EDTM":"2022-12-16 23:13:33","TRT02SDTM":"2022-12-16 23:13:33","TRT02EDTM":"2023-12-17 05:13:33","AP01SDTM":"2020-12-16 11:13:33","AP01EDTM":"2022-12-16 23:13:33","AP02SDTM":"2022-12-16 23:13:33","AP02EDTM":"2023-12-17 05:13:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7808,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96332,"AVALU":"g/L","BASE2":2.89249,"BASE":2.88598,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07082,"PCHG2":2.44847,"CHG":0.07733,"PCHG":2.67963,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-05 11:13:33","ADY":781,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-209","SUBJID":"id-209","SITEID":"CHN-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.64011,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-14","TRTSDTM":"2020-12-16 11:13:33","TRTEDTM":"2023-12-17 05:13:33","TRT01SDTM":"2020-12-16 11:13:33","TRT01EDTM":"2022-12-16 23:13:33","TRT02SDTM":"2022-12-16 23:13:33","TRT02EDTM":"2023-12-17 05:13:33","AP01SDTM":"2020-12-16 11:13:33","AP01EDTM":"2022-12-16 23:13:33","AP02SDTM":"2022-12-16 23:13:33","AP02EDTM":"2023-12-17 05:13:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3260,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88014,"AVALU":"g/L","BASE2":2.89249,"BASE":2.88598,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01235,"PCHG2":-0.42707,"CHG":-0.00584,"PCHG":-0.20239,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-27 11:13:33","ADY":862,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-209","SUBJID":"id-209","SITEID":"CHN-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.64011,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-14","TRTSDTM":"2020-12-16 11:13:33","TRTEDTM":"2023-12-17 05:13:33","TRT01SDTM":"2020-12-16 11:13:33","TRT01EDTM":"2022-12-16 23:13:33","TRT02SDTM":"2022-12-16 23:13:33","TRT02EDTM":"2023-12-17 05:13:33","AP01SDTM":"2020-12-16 11:13:33","AP01EDTM":"2022-12-16 23:13:33","AP02SDTM":"2022-12-16 23:13:33","AP02EDTM":"2023-12-17 05:13:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3802,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82861,"AVALU":"g/L","BASE2":2.89249,"BASE":2.88598,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06388,"PCHG2":-2.20857,"CHG":-0.05737,"PCHG":-1.98791,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-05 11:13:33","ADY":901,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-209","SUBJID":"id-209","SITEID":"CHN-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":1.64011,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-14","TRTSDTM":"2020-12-16 11:13:33","TRTEDTM":"2023-12-17 05:13:33","TRT01SDTM":"2020-12-16 11:13:33","TRT01EDTM":"2022-12-16 23:13:33","TRT02SDTM":"2022-12-16 23:13:33","TRT02EDTM":"2023-12-17 05:13:33","AP01SDTM":"2020-12-16 11:13:33","AP01EDTM":"2022-12-16 23:13:33","AP02SDTM":"2022-12-16 23:13:33","AP02EDTM":"2023-12-17 05:13:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-17","EOSDY":1096,"LSTALVDT":"2024-01-07","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":451,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96061,"AVALU":"g/L","BASE2":2.89249,"BASE":2.88598,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06811,"PCHG2":2.35476,"CHG":0.07462,"PCHG":2.58571,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-14 11:13:33","ADY":910,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-309","SUBJID":"id-309","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.34396,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-27","TRTSDTM":"2019-04-27 14:58:13","TRTEDTM":"2022-02-17 18:04:24","TRT01SDTM":"2019-04-27 14:58:13","TRT01EDTM":"2021-02-17 12:04:24","TRT02SDTM":"2021-02-17 12:04:24","TRT02EDTM":"2022-02-17 18:04:24","AP01SDTM":"2019-04-27 14:58:13","AP01EDTM":"2021-02-17 12:04:24","AP02SDTM":"2021-02-17 12:04:24","AP02EDTM":"2022-02-17 18:04:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1028,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-08","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2050,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.29248,"AVALU":"U/L","BASE2":3.29248,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2019-06-30 14:58:13","ADY":64,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-309","SUBJID":"id-309","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.34396,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-27","TRTSDTM":"2019-04-27 14:58:13","TRTEDTM":"2022-02-17 18:04:24","TRT01SDTM":"2019-04-27 14:58:13","TRT01EDTM":"2021-02-17 12:04:24","TRT02SDTM":"2021-02-17 12:04:24","TRT02EDTM":"2022-02-17 18:04:24","AP01SDTM":"2019-04-27 14:58:13","AP01EDTM":"2021-02-17 12:04:24","AP02SDTM":"2021-02-17 12:04:24","AP02EDTM":"2022-02-17 18:04:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1028,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-08","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4232,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.46822,"AVALU":"U/L","BASE2":3.29248,"BASE":17.46822,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":14.17574,"PCHG2":430.54948,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-03 14:58:13","ADY":159,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-309","SUBJID":"id-309","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.34396,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-27","TRTSDTM":"2019-04-27 14:58:13","TRTEDTM":"2022-02-17 18:04:24","TRT01SDTM":"2019-04-27 14:58:13","TRT01EDTM":"2021-02-17 12:04:24","TRT02SDTM":"2021-02-17 12:04:24","TRT02EDTM":"2022-02-17 18:04:24","AP01SDTM":"2019-04-27 14:58:13","AP01EDTM":"2021-02-17 12:04:24","AP02SDTM":"2021-02-17 12:04:24","AP02EDTM":"2022-02-17 18:04:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1028,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-08","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7730,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.70755,"AVALU":"U/L","BASE2":3.29248,"BASE":17.46822,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.58492,"PCHG2":-48.13775,"CHG":-15.76066,"PCHG":-90.22481,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-03-17 14:58:13","ADY":325,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-309","SUBJID":"id-309","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.34396,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-27","TRTSDTM":"2019-04-27 14:58:13","TRTEDTM":"2022-02-17 18:04:24","TRT01SDTM":"2019-04-27 14:58:13","TRT01EDTM":"2021-02-17 12:04:24","TRT02SDTM":"2021-02-17 12:04:24","TRT02EDTM":"2022-02-17 18:04:24","AP01SDTM":"2019-04-27 14:58:13","AP01EDTM":"2021-02-17 12:04:24","AP02SDTM":"2021-02-17 12:04:24","AP02EDTM":"2022-02-17 18:04:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1028,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-08","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8154,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.40473,"AVALU":"U/L","BASE2":3.29248,"BASE":17.46822,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.88774,"PCHG2":-87.70733,"CHG":-17.06348,"PCHG":-97.68303,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-04-05 14:58:13","ADY":344,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-309","SUBJID":"id-309","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.34396,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-27","TRTSDTM":"2019-04-27 14:58:13","TRTEDTM":"2022-02-17 18:04:24","TRT01SDTM":"2019-04-27 14:58:13","TRT01EDTM":"2021-02-17 12:04:24","TRT02SDTM":"2021-02-17 12:04:24","TRT02EDTM":"2022-02-17 18:04:24","AP01SDTM":"2019-04-27 14:58:13","AP01EDTM":"2021-02-17 12:04:24","AP02SDTM":"2021-02-17 12:04:24","AP02EDTM":"2022-02-17 18:04:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1028,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-08","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7159,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.02105,"AVALU":"U/L","BASE2":3.29248,"BASE":17.46822,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.72858,"PCHG2":113.24537,"CHG":-10.44716,"PCHG":-59.8067,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-18 14:58:13","ADY":387,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-309","SUBJID":"id-309","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.34396,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-27","TRTSDTM":"2019-04-27 14:58:13","TRTEDTM":"2022-02-17 18:04:24","TRT01SDTM":"2019-04-27 14:58:13","TRT01EDTM":"2021-02-17 12:04:24","TRT02SDTM":"2021-02-17 12:04:24","TRT02EDTM":"2022-02-17 18:04:24","AP01SDTM":"2019-04-27 14:58:13","AP01EDTM":"2021-02-17 12:04:24","AP02SDTM":"2021-02-17 12:04:24","AP02EDTM":"2022-02-17 18:04:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1028,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-08","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4843,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.56605,"AVALU":"U/L","BASE2":3.29248,"BASE":17.46822,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":17.27357,"PCHG2":524.63777,"CHG":3.09783,"PCHG":17.73412,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-20 14:58:13","ADY":481,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-309","SUBJID":"id-309","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.34396,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-27","TRTSDTM":"2019-04-27 14:58:13","TRTEDTM":"2022-02-17 18:04:24","TRT01SDTM":"2019-04-27 14:58:13","TRT01EDTM":"2021-02-17 12:04:24","TRT02SDTM":"2021-02-17 12:04:24","TRT02EDTM":"2022-02-17 18:04:24","AP01SDTM":"2019-04-27 14:58:13","AP01EDTM":"2021-02-17 12:04:24","AP02SDTM":"2021-02-17 12:04:24","AP02EDTM":"2022-02-17 18:04:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1028,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-08","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8212,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.07739,"AVALU":"U/L","BASE2":3.29248,"BASE":17.46822,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.78491,"PCHG2":570.54051,"CHG":4.60917,"PCHG":26.38605,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-12 14:58:13","ADY":565,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-309","SUBJID":"id-309","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.34396,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-27","TRTSDTM":"2019-04-27 14:58:13","TRTEDTM":"2022-02-17 18:04:24","TRT01SDTM":"2019-04-27 14:58:13","TRT01EDTM":"2021-02-17 12:04:24","TRT02SDTM":"2021-02-17 12:04:24","TRT02EDTM":"2022-02-17 18:04:24","AP01SDTM":"2019-04-27 14:58:13","AP01EDTM":"2021-02-17 12:04:24","AP02SDTM":"2021-02-17 12:04:24","AP02EDTM":"2022-02-17 18:04:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1028,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-08","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6348,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.39256,"AVALU":"mg/L","BASE2":8.39256,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-06-30 14:58:13","ADY":64,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-309","SUBJID":"id-309","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.34396,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-27","TRTSDTM":"2019-04-27 14:58:13","TRTEDTM":"2022-02-17 18:04:24","TRT01SDTM":"2019-04-27 14:58:13","TRT01EDTM":"2021-02-17 12:04:24","TRT02SDTM":"2021-02-17 12:04:24","TRT02EDTM":"2022-02-17 18:04:24","AP01SDTM":"2019-04-27 14:58:13","AP01EDTM":"2021-02-17 12:04:24","AP02SDTM":"2021-02-17 12:04:24","AP02EDTM":"2022-02-17 18:04:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1028,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-08","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6887,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.81914,"AVALU":"mg/L","BASE2":8.39256,"BASE":8.81914,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.42659,"PCHG2":5.08293,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-03 14:58:13","ADY":159,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-309","SUBJID":"id-309","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.34396,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-27","TRTSDTM":"2019-04-27 14:58:13","TRTEDTM":"2022-02-17 18:04:24","TRT01SDTM":"2019-04-27 14:58:13","TRT01EDTM":"2021-02-17 12:04:24","TRT02SDTM":"2021-02-17 12:04:24","TRT02EDTM":"2022-02-17 18:04:24","AP01SDTM":"2019-04-27 14:58:13","AP01EDTM":"2021-02-17 12:04:24","AP02SDTM":"2021-02-17 12:04:24","AP02EDTM":"2022-02-17 18:04:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1028,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-08","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1664,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.96223,"AVALU":"mg/L","BASE2":8.39256,"BASE":8.81914,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.43032,"PCHG2":-5.12745,"CHG":-0.85691,"PCHG":-9.7165,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-03-17 14:58:13","ADY":325,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-309","SUBJID":"id-309","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.34396,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-27","TRTSDTM":"2019-04-27 14:58:13","TRTEDTM":"2022-02-17 18:04:24","TRT01SDTM":"2019-04-27 14:58:13","TRT01EDTM":"2021-02-17 12:04:24","TRT02SDTM":"2021-02-17 12:04:24","TRT02EDTM":"2022-02-17 18:04:24","AP01SDTM":"2019-04-27 14:58:13","AP01EDTM":"2021-02-17 12:04:24","AP02SDTM":"2021-02-17 12:04:24","AP02EDTM":"2022-02-17 18:04:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1028,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-08","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":249,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.43209,"AVALU":"mg/L","BASE2":8.39256,"BASE":8.81914,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.03953,"PCHG2":12.38635,"CHG":0.61294,"PCHG":6.95014,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-05 14:58:13","ADY":344,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-309","SUBJID":"id-309","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.34396,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-27","TRTSDTM":"2019-04-27 14:58:13","TRTEDTM":"2022-02-17 18:04:24","TRT01SDTM":"2019-04-27 14:58:13","TRT01EDTM":"2021-02-17 12:04:24","TRT02SDTM":"2021-02-17 12:04:24","TRT02EDTM":"2022-02-17 18:04:24","AP01SDTM":"2019-04-27 14:58:13","AP01EDTM":"2021-02-17 12:04:24","AP02SDTM":"2021-02-17 12:04:24","AP02EDTM":"2022-02-17 18:04:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1028,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-08","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5892,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.45071,"AVALU":"mg/L","BASE2":8.39256,"BASE":8.81914,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.05815,"PCHG2":12.60822,"CHG":0.63156,"PCHG":7.16128,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-18 14:58:13","ADY":387,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-309","SUBJID":"id-309","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.34396,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-27","TRTSDTM":"2019-04-27 14:58:13","TRTEDTM":"2022-02-17 18:04:24","TRT01SDTM":"2019-04-27 14:58:13","TRT01EDTM":"2021-02-17 12:04:24","TRT02SDTM":"2021-02-17 12:04:24","TRT02EDTM":"2022-02-17 18:04:24","AP01SDTM":"2019-04-27 14:58:13","AP01EDTM":"2021-02-17 12:04:24","AP02SDTM":"2021-02-17 12:04:24","AP02EDTM":"2022-02-17 18:04:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1028,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-08","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6883,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.81171,"AVALU":"mg/L","BASE2":8.39256,"BASE":8.81914,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.41916,"PCHG2":28.82502,"CHG":1.99257,"PCHG":22.59366,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-08-20 14:58:13","ADY":481,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-309","SUBJID":"id-309","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.34396,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-27","TRTSDTM":"2019-04-27 14:58:13","TRTEDTM":"2022-02-17 18:04:24","TRT01SDTM":"2019-04-27 14:58:13","TRT01EDTM":"2021-02-17 12:04:24","TRT02SDTM":"2021-02-17 12:04:24","TRT02EDTM":"2022-02-17 18:04:24","AP01SDTM":"2019-04-27 14:58:13","AP01EDTM":"2021-02-17 12:04:24","AP02SDTM":"2021-02-17 12:04:24","AP02EDTM":"2022-02-17 18:04:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1028,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-08","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5998,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.26945,"AVALU":"mg/L","BASE2":8.39256,"BASE":8.81914,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1231,"PCHG2":-1.46681,"CHG":-0.54969,"PCHG":-6.23293,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-12 14:58:13","ADY":565,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-309","SUBJID":"id-309","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.34396,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-27","TRTSDTM":"2019-04-27 14:58:13","TRTEDTM":"2022-02-17 18:04:24","TRT01SDTM":"2019-04-27 14:58:13","TRT01EDTM":"2021-02-17 12:04:24","TRT02SDTM":"2021-02-17 12:04:24","TRT02EDTM":"2022-02-17 18:04:24","AP01SDTM":"2019-04-27 14:58:13","AP01EDTM":"2021-02-17 12:04:24","AP02SDTM":"2021-02-17 12:04:24","AP02EDTM":"2022-02-17 18:04:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1028,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-08","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7128,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.08964,"AVALU":"g/L","BASE2":3.08964,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"2","BTOXGR":"0","ADTM":"2019-06-30 14:58:13","ADY":64,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-309","SUBJID":"id-309","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.34396,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-27","TRTSDTM":"2019-04-27 14:58:13","TRTEDTM":"2022-02-17 18:04:24","TRT01SDTM":"2019-04-27 14:58:13","TRT01EDTM":"2021-02-17 12:04:24","TRT02SDTM":"2021-02-17 12:04:24","TRT02EDTM":"2022-02-17 18:04:24","AP01SDTM":"2019-04-27 14:58:13","AP01EDTM":"2021-02-17 12:04:24","AP02SDTM":"2021-02-17 12:04:24","AP02EDTM":"2022-02-17 18:04:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1028,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-08","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8354,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96816,"AVALU":"g/L","BASE2":3.08964,"BASE":2.96816,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.12148,"PCHG2":-3.93191,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-03 14:58:13","ADY":159,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-309","SUBJID":"id-309","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.34396,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-27","TRTSDTM":"2019-04-27 14:58:13","TRTEDTM":"2022-02-17 18:04:24","TRT01SDTM":"2019-04-27 14:58:13","TRT01EDTM":"2021-02-17 12:04:24","TRT02SDTM":"2021-02-17 12:04:24","TRT02EDTM":"2022-02-17 18:04:24","AP01SDTM":"2019-04-27 14:58:13","AP01EDTM":"2021-02-17 12:04:24","AP02SDTM":"2021-02-17 12:04:24","AP02EDTM":"2022-02-17 18:04:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1028,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-08","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1925,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78797,"AVALU":"g/L","BASE2":3.08964,"BASE":2.96816,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.30167,"PCHG2":-9.76395,"CHG":-0.18019,"PCHG":-6.07074,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-17 14:58:13","ADY":325,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-309","SUBJID":"id-309","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.34396,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-27","TRTSDTM":"2019-04-27 14:58:13","TRTEDTM":"2022-02-17 18:04:24","TRT01SDTM":"2019-04-27 14:58:13","TRT01EDTM":"2021-02-17 12:04:24","TRT02SDTM":"2021-02-17 12:04:24","TRT02EDTM":"2022-02-17 18:04:24","AP01SDTM":"2019-04-27 14:58:13","AP01EDTM":"2021-02-17 12:04:24","AP02SDTM":"2021-02-17 12:04:24","AP02EDTM":"2022-02-17 18:04:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1028,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-08","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2605,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.71354,"AVALU":"g/L","BASE2":3.08964,"BASE":2.96816,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.3761,"PCHG2":-12.17281,"CHG":-0.25461,"PCHG":-8.57819,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-05 14:58:13","ADY":344,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-309","SUBJID":"id-309","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.34396,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-27","TRTSDTM":"2019-04-27 14:58:13","TRTEDTM":"2022-02-17 18:04:24","TRT01SDTM":"2019-04-27 14:58:13","TRT01EDTM":"2021-02-17 12:04:24","TRT02SDTM":"2021-02-17 12:04:24","TRT02EDTM":"2022-02-17 18:04:24","AP01SDTM":"2019-04-27 14:58:13","AP01EDTM":"2021-02-17 12:04:24","AP02SDTM":"2021-02-17 12:04:24","AP02EDTM":"2022-02-17 18:04:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1028,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-08","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2866,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97606,"AVALU":"g/L","BASE2":3.08964,"BASE":2.96816,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11358,"PCHG2":-3.67626,"CHG":0.0079,"PCHG":0.26611,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-18 14:58:13","ADY":387,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-309","SUBJID":"id-309","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.34396,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-27","TRTSDTM":"2019-04-27 14:58:13","TRTEDTM":"2022-02-17 18:04:24","TRT01SDTM":"2019-04-27 14:58:13","TRT01EDTM":"2021-02-17 12:04:24","TRT02SDTM":"2021-02-17 12:04:24","TRT02EDTM":"2022-02-17 18:04:24","AP01SDTM":"2019-04-27 14:58:13","AP01EDTM":"2021-02-17 12:04:24","AP02SDTM":"2021-02-17 12:04:24","AP02EDTM":"2022-02-17 18:04:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1028,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-08","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4146,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.15789,"AVALU":"g/L","BASE2":3.08964,"BASE":2.96816,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06825,"PCHG2":2.2091,"CHG":0.18974,"PCHG":6.39235,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-08-20 14:58:13","ADY":481,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-309","SUBJID":"id-309","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.34396,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-27","TRTSDTM":"2019-04-27 14:58:13","TRTEDTM":"2022-02-17 18:04:24","TRT01SDTM":"2019-04-27 14:58:13","TRT01EDTM":"2021-02-17 12:04:24","TRT02SDTM":"2021-02-17 12:04:24","TRT02EDTM":"2022-02-17 18:04:24","AP01SDTM":"2019-04-27 14:58:13","AP01EDTM":"2021-02-17 12:04:24","AP02SDTM":"2021-02-17 12:04:24","AP02EDTM":"2022-02-17 18:04:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":1028,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-08","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7173,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85818,"AVALU":"g/L","BASE2":3.08964,"BASE":2.96816,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.23146,"PCHG2":-7.4914,"CHG":-0.10998,"PCHG":-3.70518,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-12 14:58:13","ADY":565,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-31","SUBJID":"id-31","SITEID":"CHN-17","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.47905,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-11-15","TRTSDTM":"2019-11-17 06:57:47","TRT01SDTM":"2019-11-17 06:57:47","AP01SDTM":"2019-11-17 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6130,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.14359,"AVALU":"U/L","BASE2":1.14359,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2019-12-14 06:57:47","ADY":27,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-31","SUBJID":"id-31","SITEID":"CHN-17","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.47905,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-11-15","TRTSDTM":"2019-11-17 06:57:47","TRT01SDTM":"2019-11-17 06:57:47","AP01SDTM":"2019-11-17 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":112,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.36237,"AVALU":"U/L","BASE2":1.14359,"BASE":2.36237,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.21878,"PCHG2":106.57451,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2020-07-26 06:57:47","ADY":252,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-31","SUBJID":"id-31","SITEID":"CHN-17","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.47905,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-11-15","TRTSDTM":"2019-11-17 06:57:47","TRT01SDTM":"2019-11-17 06:57:47","AP01SDTM":"2019-11-17 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2282,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.23466,"AVALU":"U/L","BASE2":1.14359,"BASE":2.36237,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":17.09106,"PCHG2":1494.50404,"CHG":15.87228,"PCHG":671.87842,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-08-11 06:57:47","ADY":268,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-31","SUBJID":"id-31","SITEID":"CHN-17","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.47905,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-11-15","TRTSDTM":"2019-11-17 06:57:47","TRT01SDTM":"2019-11-17 06:57:47","AP01SDTM":"2019-11-17 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4423,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.90144,"AVALU":"U/L","BASE2":1.14359,"BASE":2.36237,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.75784,"PCHG2":328.5994,"CHG":2.53906,"PCHG":107.47933,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-4","BTOXGR":"-1","ADTM":"2020-11-07 06:57:47","ADY":356,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-31","SUBJID":"id-31","SITEID":"CHN-17","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.47905,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-11-15","TRTSDTM":"2019-11-17 06:57:47","TRT01SDTM":"2019-11-17 06:57:47","AP01SDTM":"2019-11-17 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1873,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.39074,"AVALU":"U/L","BASE2":1.14359,"BASE":2.36237,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":24.24715,"PCHG2":2120.25808,"CHG":23.02837,"PCHG":974.79771,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-02-09 06:57:47","ADY":450,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-31","SUBJID":"id-31","SITEID":"CHN-17","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.47905,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-11-15","TRTSDTM":"2019-11-17 06:57:47","TRT01SDTM":"2019-11-17 06:57:47","AP01SDTM":"2019-11-17 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":150,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.96532,"AVALU":"U/L","BASE2":1.14359,"BASE":2.36237,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.82173,"PCHG2":1645.83954,"CHG":17.60295,"PCHG":745.13794,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-03-15 06:57:47","ADY":484,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-31","SUBJID":"id-31","SITEID":"CHN-17","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.47905,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-11-15","TRTSDTM":"2019-11-17 06:57:47","TRT01SDTM":"2019-11-17 06:57:47","AP01SDTM":"2019-11-17 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5602,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.5236,"AVALU":"U/L","BASE2":1.14359,"BASE":2.36237,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.38001,"PCHG2":907.6651,"CHG":9.16123,"PCHG":387.79741,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-09-01 06:57:47","ADY":654,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-31","SUBJID":"id-31","SITEID":"CHN-17","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.47905,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-11-15","TRTSDTM":"2019-11-17 06:57:47","TRT01SDTM":"2019-11-17 06:57:47","AP01SDTM":"2019-11-17 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5486,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.392,"AVALU":"mg/L","BASE2":8.392,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-14 06:57:47","ADY":27,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-31","SUBJID":"id-31","SITEID":"CHN-17","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.47905,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-11-15","TRTSDTM":"2019-11-17 06:57:47","TRT01SDTM":"2019-11-17 06:57:47","AP01SDTM":"2019-11-17 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6469,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.15804,"AVALU":"mg/L","BASE2":8.392,"BASE":9.15804,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.76604,"PCHG2":9.12824,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-26 06:57:47","ADY":252,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-31","SUBJID":"id-31","SITEID":"CHN-17","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.47905,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-11-15","TRTSDTM":"2019-11-17 06:57:47","TRT01SDTM":"2019-11-17 06:57:47","AP01SDTM":"2019-11-17 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4067,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.07534,"AVALU":"mg/L","BASE2":8.392,"BASE":9.15804,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.68335,"PCHG2":20.05894,"CHG":0.9173,"PCHG":10.01638,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-08-11 06:57:47","ADY":268,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-31","SUBJID":"id-31","SITEID":"CHN-17","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.47905,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-11-15","TRTSDTM":"2019-11-17 06:57:47","TRT01SDTM":"2019-11-17 06:57:47","AP01SDTM":"2019-11-17 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7816,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.30036,"AVALU":"mg/L","BASE2":8.392,"BASE":9.15804,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.90836,"PCHG2":10.82414,"CHG":0.14232,"PCHG":1.55405,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-07 06:57:47","ADY":356,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-31","SUBJID":"id-31","SITEID":"CHN-17","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.47905,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-11-15","TRTSDTM":"2019-11-17 06:57:47","TRT01SDTM":"2019-11-17 06:57:47","AP01SDTM":"2019-11-17 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5051,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.57585,"AVALU":"mg/L","BASE2":8.392,"BASE":9.15804,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.18385,"PCHG2":14.10691,"CHG":0.41781,"PCHG":4.56222,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-09 06:57:47","ADY":450,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-31","SUBJID":"id-31","SITEID":"CHN-17","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.47905,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-11-15","TRTSDTM":"2019-11-17 06:57:47","TRT01SDTM":"2019-11-17 06:57:47","AP01SDTM":"2019-11-17 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7238,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.50151,"AVALU":"mg/L","BASE2":8.392,"BASE":9.15804,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.89049,"PCHG2":-10.61114,"CHG":-1.65653,"PCHG":-18.08824,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-03-15 06:57:47","ADY":484,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-31","SUBJID":"id-31","SITEID":"CHN-17","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.47905,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-11-15","TRTSDTM":"2019-11-17 06:57:47","TRT01SDTM":"2019-11-17 06:57:47","AP01SDTM":"2019-11-17 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8064,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.80871,"AVALU":"mg/L","BASE2":8.392,"BASE":9.15804,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.41671,"PCHG2":16.88171,"CHG":0.65067,"PCHG":7.10491,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-01 06:57:47","ADY":654,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-31","SUBJID":"id-31","SITEID":"CHN-17","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.47905,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-11-15","TRTSDTM":"2019-11-17 06:57:47","TRT01SDTM":"2019-11-17 06:57:47","AP01SDTM":"2019-11-17 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3063,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79238,"AVALU":"g/L","BASE2":2.79238,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-14 06:57:47","ADY":27,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-31","SUBJID":"id-31","SITEID":"CHN-17","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.47905,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-11-15","TRTSDTM":"2019-11-17 06:57:47","TRT01SDTM":"2019-11-17 06:57:47","AP01SDTM":"2019-11-17 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1108,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90176,"AVALU":"g/L","BASE2":2.79238,"BASE":2.90176,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.10938,"PCHG2":3.91697,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-26 06:57:47","ADY":252,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-31","SUBJID":"id-31","SITEID":"CHN-17","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.47905,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-11-15","TRTSDTM":"2019-11-17 06:57:47","TRT01SDTM":"2019-11-17 06:57:47","AP01SDTM":"2019-11-17 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":449,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96574,"AVALU":"g/L","BASE2":2.79238,"BASE":2.90176,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17335,"PCHG2":6.20807,"CHG":0.06398,"PCHG":2.20474,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-11 06:57:47","ADY":268,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-31","SUBJID":"id-31","SITEID":"CHN-17","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.47905,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-11-15","TRTSDTM":"2019-11-17 06:57:47","TRT01SDTM":"2019-11-17 06:57:47","AP01SDTM":"2019-11-17 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4949,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92657,"AVALU":"g/L","BASE2":2.79238,"BASE":2.90176,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13419,"PCHG2":4.80547,"CHG":0.02481,"PCHG":0.85501,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-07 06:57:47","ADY":356,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-31","SUBJID":"id-31","SITEID":"CHN-17","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.47905,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-11-15","TRTSDTM":"2019-11-17 06:57:47","TRT01SDTM":"2019-11-17 06:57:47","AP01SDTM":"2019-11-17 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":301,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95687,"AVALU":"g/L","BASE2":2.79238,"BASE":2.90176,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16449,"PCHG2":5.89053,"CHG":0.05511,"PCHG":1.89917,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-09 06:57:47","ADY":450,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-31","SUBJID":"id-31","SITEID":"CHN-17","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.47905,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-11-15","TRTSDTM":"2019-11-17 06:57:47","TRT01SDTM":"2019-11-17 06:57:47","AP01SDTM":"2019-11-17 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1782,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78757,"AVALU":"g/L","BASE2":2.79238,"BASE":2.90176,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00481,"PCHG2":-0.17239,"CHG":-0.11419,"PCHG":-3.93521,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-15 06:57:47","ADY":484,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-31","SUBJID":"id-31","SITEID":"CHN-17","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.47905,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-11-15","TRTSDTM":"2019-11-17 06:57:47","TRT01SDTM":"2019-11-17 06:57:47","AP01SDTM":"2019-11-17 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5745,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78016,"AVALU":"g/L","BASE2":2.79238,"BASE":2.90176,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01223,"PCHG2":-0.4379,"CHG":-0.1216,"PCHG":-4.19072,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-01 06:57:47","ADY":654,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-48","SUBJID":"id-48","SITEID":"CHN-17","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.25469,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-29","TRTSDTM":"2019-05-03 06:19:35","TRTEDTM":"2022-05-03 00:19:35","TRT01SDTM":"2019-05-03 06:19:35","TRT01EDTM":"2021-05-02 18:19:35","TRT02SDTM":"2021-05-02 18:19:35","TRT02EDTM":"2022-05-03 00:19:35","AP01SDTM":"2019-05-03 06:19:35","AP01EDTM":"2021-05-02 18:19:35","AP02SDTM":"2021-05-02 18:19:35","AP02EDTM":"2022-05-03 00:19:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-21","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3539,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.85005,"AVALU":"U/L","BASE2":13.85005,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-23 06:19:35","ADY":143,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-48","SUBJID":"id-48","SITEID":"CHN-17","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.25469,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-29","TRTSDTM":"2019-05-03 06:19:35","TRTEDTM":"2022-05-03 00:19:35","TRT01SDTM":"2019-05-03 06:19:35","TRT01EDTM":"2021-05-02 18:19:35","TRT02SDTM":"2021-05-02 18:19:35","TRT02EDTM":"2022-05-03 00:19:35","AP01SDTM":"2019-05-03 06:19:35","AP01EDTM":"2021-05-02 18:19:35","AP02SDTM":"2021-05-02 18:19:35","AP02EDTM":"2022-05-03 00:19:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-21","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1582,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.47801,"AVALU":"U/L","BASE2":13.85005,"BASE":26.47801,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":12.62796,"PCHG2":91.17625,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-24 06:19:35","ADY":235,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-48","SUBJID":"id-48","SITEID":"CHN-17","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.25469,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-29","TRTSDTM":"2019-05-03 06:19:35","TRTEDTM":"2022-05-03 00:19:35","TRT01SDTM":"2019-05-03 06:19:35","TRT01EDTM":"2021-05-02 18:19:35","TRT02SDTM":"2021-05-02 18:19:35","TRT02EDTM":"2022-05-03 00:19:35","AP01SDTM":"2019-05-03 06:19:35","AP01EDTM":"2021-05-02 18:19:35","AP02SDTM":"2021-05-02 18:19:35","AP02EDTM":"2022-05-03 00:19:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-21","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5959,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.47568,"AVALU":"U/L","BASE2":13.85005,"BASE":26.47801,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.62562,"PCHG2":62.27863,"CHG":-4.00233,"PCHG":-15.11569,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-22 06:19:35","ADY":416,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-48","SUBJID":"id-48","SITEID":"CHN-17","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.25469,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-29","TRTSDTM":"2019-05-03 06:19:35","TRTEDTM":"2022-05-03 00:19:35","TRT01SDTM":"2019-05-03 06:19:35","TRT01EDTM":"2021-05-02 18:19:35","TRT02SDTM":"2021-05-02 18:19:35","TRT02EDTM":"2022-05-03 00:19:35","AP01SDTM":"2019-05-03 06:19:35","AP01EDTM":"2021-05-02 18:19:35","AP02SDTM":"2021-05-02 18:19:35","AP02EDTM":"2022-05-03 00:19:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-21","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7600,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.56037,"AVALU":"U/L","BASE2":13.85005,"BASE":26.47801,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.28969,"PCHG2":-88.73387,"CHG":-24.91765,"PCHG":-94.10694,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-07-10 06:19:35","ADY":434,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-48","SUBJID":"id-48","SITEID":"CHN-17","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.25469,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-29","TRTSDTM":"2019-05-03 06:19:35","TRTEDTM":"2022-05-03 00:19:35","TRT01SDTM":"2019-05-03 06:19:35","TRT01EDTM":"2021-05-02 18:19:35","TRT02SDTM":"2021-05-02 18:19:35","TRT02EDTM":"2022-05-03 00:19:35","AP01SDTM":"2019-05-03 06:19:35","AP01EDTM":"2021-05-02 18:19:35","AP02SDTM":"2021-05-02 18:19:35","AP02EDTM":"2022-05-03 00:19:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-21","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2644,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.45522,"AVALU":"U/L","BASE2":13.85005,"BASE":26.47801,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.39483,"PCHG2":-75.05266,"CHG":-23.02279,"PCHG":-86.95061,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-03-27 06:19:35","ADY":694,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-48","SUBJID":"id-48","SITEID":"CHN-17","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.25469,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-29","TRTSDTM":"2019-05-03 06:19:35","TRTEDTM":"2022-05-03 00:19:35","TRT01SDTM":"2019-05-03 06:19:35","TRT01EDTM":"2021-05-02 18:19:35","TRT02SDTM":"2021-05-02 18:19:35","TRT02EDTM":"2022-05-03 00:19:35","AP01SDTM":"2019-05-03 06:19:35","AP01EDTM":"2021-05-02 18:19:35","AP02SDTM":"2021-05-02 18:19:35","AP02EDTM":"2022-05-03 00:19:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-21","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7756,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.1863,"AVALU":"U/L","BASE2":13.85005,"BASE":26.47801,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.66376,"PCHG2":-26.45301,"CHG":-16.29172,"PCHG":-61.52922,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-08 06:19:35","ADY":1012,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-48","SUBJID":"id-48","SITEID":"CHN-17","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.25469,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-29","TRTSDTM":"2019-05-03 06:19:35","TRTEDTM":"2022-05-03 00:19:35","TRT01SDTM":"2019-05-03 06:19:35","TRT01EDTM":"2021-05-02 18:19:35","TRT02SDTM":"2021-05-02 18:19:35","TRT02EDTM":"2022-05-03 00:19:35","AP01SDTM":"2019-05-03 06:19:35","AP01EDTM":"2021-05-02 18:19:35","AP02SDTM":"2021-05-02 18:19:35","AP02EDTM":"2022-05-03 00:19:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-21","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5796,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.09913,"AVALU":"U/L","BASE2":13.85005,"BASE":26.47801,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.75092,"PCHG2":-63.1833,"CHG":-21.37888,"PCHG":-80.74201,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2022-02-20 06:19:35","ADY":1024,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-48","SUBJID":"id-48","SITEID":"CHN-17","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.25469,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-29","TRTSDTM":"2019-05-03 06:19:35","TRTEDTM":"2022-05-03 00:19:35","TRT01SDTM":"2019-05-03 06:19:35","TRT01EDTM":"2021-05-02 18:19:35","TRT02SDTM":"2021-05-02 18:19:35","TRT02EDTM":"2022-05-03 00:19:35","AP01SDTM":"2019-05-03 06:19:35","AP01EDTM":"2021-05-02 18:19:35","AP02SDTM":"2021-05-02 18:19:35","AP02EDTM":"2022-05-03 00:19:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-21","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6910,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.48475,"AVALU":"mg/L","BASE2":9.48475,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-23 06:19:35","ADY":143,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-48","SUBJID":"id-48","SITEID":"CHN-17","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.25469,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-29","TRTSDTM":"2019-05-03 06:19:35","TRTEDTM":"2022-05-03 00:19:35","TRT01SDTM":"2019-05-03 06:19:35","TRT01EDTM":"2021-05-02 18:19:35","TRT02SDTM":"2021-05-02 18:19:35","TRT02EDTM":"2022-05-03 00:19:35","AP01SDTM":"2019-05-03 06:19:35","AP01EDTM":"2021-05-02 18:19:35","AP02SDTM":"2021-05-02 18:19:35","AP02EDTM":"2022-05-03 00:19:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-21","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5008,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.49927,"AVALU":"mg/L","BASE2":9.48475,"BASE":9.49927,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.01452,"PCHG2":0.15306,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-24 06:19:35","ADY":235,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-48","SUBJID":"id-48","SITEID":"CHN-17","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.25469,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-29","TRTSDTM":"2019-05-03 06:19:35","TRTEDTM":"2022-05-03 00:19:35","TRT01SDTM":"2019-05-03 06:19:35","TRT01EDTM":"2021-05-02 18:19:35","TRT02SDTM":"2021-05-02 18:19:35","TRT02EDTM":"2022-05-03 00:19:35","AP01SDTM":"2019-05-03 06:19:35","AP01EDTM":"2021-05-02 18:19:35","AP02SDTM":"2021-05-02 18:19:35","AP02EDTM":"2022-05-03 00:19:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-21","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4127,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.25834,"AVALU":"mg/L","BASE2":9.48475,"BASE":9.49927,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.22641,"PCHG2":-2.3871,"CHG":-0.24093,"PCHG":-2.53628,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-22 06:19:35","ADY":416,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-48","SUBJID":"id-48","SITEID":"CHN-17","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.25469,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-29","TRTSDTM":"2019-05-03 06:19:35","TRTEDTM":"2022-05-03 00:19:35","TRT01SDTM":"2019-05-03 06:19:35","TRT01EDTM":"2021-05-02 18:19:35","TRT02SDTM":"2021-05-02 18:19:35","TRT02EDTM":"2022-05-03 00:19:35","AP01SDTM":"2019-05-03 06:19:35","AP01EDTM":"2021-05-02 18:19:35","AP02SDTM":"2021-05-02 18:19:35","AP02EDTM":"2022-05-03 00:19:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-21","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4451,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.07303,"AVALU":"mg/L","BASE2":9.48475,"BASE":9.49927,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.41173,"PCHG2":-4.34093,"CHG":-0.42624,"PCHG":-4.48712,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-10 06:19:35","ADY":434,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-48","SUBJID":"id-48","SITEID":"CHN-17","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.25469,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-29","TRTSDTM":"2019-05-03 06:19:35","TRTEDTM":"2022-05-03 00:19:35","TRT01SDTM":"2019-05-03 06:19:35","TRT01EDTM":"2021-05-02 18:19:35","TRT02SDTM":"2021-05-02 18:19:35","TRT02EDTM":"2022-05-03 00:19:35","AP01SDTM":"2019-05-03 06:19:35","AP01EDTM":"2021-05-02 18:19:35","AP02SDTM":"2021-05-02 18:19:35","AP02EDTM":"2022-05-03 00:19:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-21","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4654,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.08527,"AVALU":"mg/L","BASE2":9.48475,"BASE":9.49927,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.39948,"PCHG2":-14.7551,"CHG":-1.414,"PCHG":-14.88537,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-27 06:19:35","ADY":694,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-48","SUBJID":"id-48","SITEID":"CHN-17","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.25469,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-29","TRTSDTM":"2019-05-03 06:19:35","TRTEDTM":"2022-05-03 00:19:35","TRT01SDTM":"2019-05-03 06:19:35","TRT01EDTM":"2021-05-02 18:19:35","TRT02SDTM":"2021-05-02 18:19:35","TRT02EDTM":"2022-05-03 00:19:35","AP01SDTM":"2019-05-03 06:19:35","AP01EDTM":"2021-05-02 18:19:35","AP02SDTM":"2021-05-02 18:19:35","AP02EDTM":"2022-05-03 00:19:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-21","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6394,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.76349,"AVALU":"mg/L","BASE2":9.48475,"BASE":9.49927,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.72126,"PCHG2":-7.60443,"CHG":-0.73578,"PCHG":-7.74563,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-08 06:19:35","ADY":1012,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-48","SUBJID":"id-48","SITEID":"CHN-17","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.25469,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-29","TRTSDTM":"2019-05-03 06:19:35","TRTEDTM":"2022-05-03 00:19:35","TRT01SDTM":"2019-05-03 06:19:35","TRT01EDTM":"2021-05-02 18:19:35","TRT02SDTM":"2021-05-02 18:19:35","TRT02EDTM":"2022-05-03 00:19:35","AP01SDTM":"2019-05-03 06:19:35","AP01EDTM":"2021-05-02 18:19:35","AP02SDTM":"2021-05-02 18:19:35","AP02EDTM":"2022-05-03 00:19:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-21","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6484,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.70366,"AVALU":"mg/L","BASE2":9.48475,"BASE":9.49927,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.78109,"PCHG2":-8.23524,"CHG":-0.79561,"PCHG":-8.37547,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-20 06:19:35","ADY":1024,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-48","SUBJID":"id-48","SITEID":"CHN-17","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.25469,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-29","TRTSDTM":"2019-05-03 06:19:35","TRTEDTM":"2022-05-03 00:19:35","TRT01SDTM":"2019-05-03 06:19:35","TRT01EDTM":"2021-05-02 18:19:35","TRT02SDTM":"2021-05-02 18:19:35","TRT02EDTM":"2022-05-03 00:19:35","AP01SDTM":"2019-05-03 06:19:35","AP01EDTM":"2021-05-02 18:19:35","AP02SDTM":"2021-05-02 18:19:35","AP02EDTM":"2022-05-03 00:19:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-21","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4652,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01145,"AVALU":"g/L","BASE2":3.01145,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"4","BTOXGR":"0","ADTM":"2019-09-23 06:19:35","ADY":143,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-48","SUBJID":"id-48","SITEID":"CHN-17","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.25469,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-29","TRTSDTM":"2019-05-03 06:19:35","TRTEDTM":"2022-05-03 00:19:35","TRT01SDTM":"2019-05-03 06:19:35","TRT01EDTM":"2021-05-02 18:19:35","TRT02SDTM":"2021-05-02 18:19:35","TRT02EDTM":"2022-05-03 00:19:35","AP01SDTM":"2019-05-03 06:19:35","AP01EDTM":"2021-05-02 18:19:35","AP02SDTM":"2021-05-02 18:19:35","AP02EDTM":"2022-05-03 00:19:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-21","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6436,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90949,"AVALU":"g/L","BASE2":3.01145,"BASE":2.90949,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.10196,"PCHG2":-3.38589,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-24 06:19:35","ADY":235,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-48","SUBJID":"id-48","SITEID":"CHN-17","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.25469,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-29","TRTSDTM":"2019-05-03 06:19:35","TRTEDTM":"2022-05-03 00:19:35","TRT01SDTM":"2019-05-03 06:19:35","TRT01EDTM":"2021-05-02 18:19:35","TRT02SDTM":"2021-05-02 18:19:35","TRT02EDTM":"2022-05-03 00:19:35","AP01SDTM":"2019-05-03 06:19:35","AP01EDTM":"2021-05-02 18:19:35","AP02SDTM":"2021-05-02 18:19:35","AP02EDTM":"2022-05-03 00:19:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-21","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1438,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88477,"AVALU":"g/L","BASE2":3.01145,"BASE":2.90949,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12669,"PCHG2":-4.20685,"CHG":-0.02472,"PCHG":-0.84973,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-22 06:19:35","ADY":416,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-48","SUBJID":"id-48","SITEID":"CHN-17","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.25469,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-29","TRTSDTM":"2019-05-03 06:19:35","TRTEDTM":"2022-05-03 00:19:35","TRT01SDTM":"2019-05-03 06:19:35","TRT01EDTM":"2021-05-02 18:19:35","TRT02SDTM":"2021-05-02 18:19:35","TRT02EDTM":"2022-05-03 00:19:35","AP01SDTM":"2019-05-03 06:19:35","AP01EDTM":"2021-05-02 18:19:35","AP02SDTM":"2021-05-02 18:19:35","AP02EDTM":"2022-05-03 00:19:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-21","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2796,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01898,"AVALU":"g/L","BASE2":3.01145,"BASE":2.90949,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00753,"PCHG2":0.25001,"CHG":0.10949,"PCHG":3.76332,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-07-10 06:19:35","ADY":434,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-48","SUBJID":"id-48","SITEID":"CHN-17","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.25469,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-29","TRTSDTM":"2019-05-03 06:19:35","TRTEDTM":"2022-05-03 00:19:35","TRT01SDTM":"2019-05-03 06:19:35","TRT01EDTM":"2021-05-02 18:19:35","TRT02SDTM":"2021-05-02 18:19:35","TRT02EDTM":"2022-05-03 00:19:35","AP01SDTM":"2019-05-03 06:19:35","AP01EDTM":"2021-05-02 18:19:35","AP02SDTM":"2021-05-02 18:19:35","AP02EDTM":"2022-05-03 00:19:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-21","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1618,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87544,"AVALU":"g/L","BASE2":3.01145,"BASE":2.90949,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13601,"PCHG2":-4.51655,"CHG":-0.03405,"PCHG":-1.17028,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-27 06:19:35","ADY":694,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-48","SUBJID":"id-48","SITEID":"CHN-17","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.25469,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-29","TRTSDTM":"2019-05-03 06:19:35","TRTEDTM":"2022-05-03 00:19:35","TRT01SDTM":"2019-05-03 06:19:35","TRT01EDTM":"2021-05-02 18:19:35","TRT02SDTM":"2021-05-02 18:19:35","TRT02EDTM":"2022-05-03 00:19:35","AP01SDTM":"2019-05-03 06:19:35","AP01EDTM":"2021-05-02 18:19:35","AP02SDTM":"2021-05-02 18:19:35","AP02EDTM":"2022-05-03 00:19:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-21","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":574,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8968,"AVALU":"g/L","BASE2":3.01145,"BASE":2.90949,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11466,"PCHG2":-3.80737,"CHG":-0.01269,"PCHG":-0.43625,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-08 06:19:35","ADY":1012,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-48","SUBJID":"id-48","SITEID":"CHN-17","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":7.25469,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-04-29","TRTSDTM":"2019-05-03 06:19:35","TRTEDTM":"2022-05-03 00:19:35","TRT01SDTM":"2019-05-03 06:19:35","TRT01EDTM":"2021-05-02 18:19:35","TRT02SDTM":"2021-05-02 18:19:35","TRT02EDTM":"2022-05-03 00:19:35","AP01SDTM":"2019-05-03 06:19:35","AP01EDTM":"2021-05-02 18:19:35","AP02SDTM":"2021-05-02 18:19:35","AP02EDTM":"2022-05-03 00:19:35","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-21","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8367,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93361,"AVALU":"g/L","BASE2":3.01145,"BASE":2.90949,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07784,"PCHG2":-2.5848,"CHG":0.02412,"PCHG":0.82916,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-20 06:19:35","ADY":1024,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-5","SUBJID":"id-5","SITEID":"CHN-17","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.86288,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-04","TRTSDTM":"2021-01-07 03:52:51","TRTEDTM":"2024-01-07 21:52:51","TRT01SDTM":"2021-01-07 03:52:51","TRT01EDTM":"2023-01-07 15:52:51","TRT02SDTM":"2023-01-07 15:52:51","TRT02EDTM":"2024-01-07 21:52:51","AP01SDTM":"2021-01-07 03:52:51","AP01EDTM":"2023-01-07 15:52:51","AP02SDTM":"2023-01-07 15:52:51","AP02EDTM":"2024-01-07 21:52:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-30","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3988,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":35.63552,"AVALU":"U/L","BASE2":35.63552,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-27 03:52:51","ADY":110,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-5","SUBJID":"id-5","SITEID":"CHN-17","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.86288,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-04","TRTSDTM":"2021-01-07 03:52:51","TRTEDTM":"2024-01-07 21:52:51","TRT01SDTM":"2021-01-07 03:52:51","TRT01EDTM":"2023-01-07 15:52:51","TRT02SDTM":"2023-01-07 15:52:51","TRT02EDTM":"2024-01-07 21:52:51","AP01SDTM":"2021-01-07 03:52:51","AP01EDTM":"2023-01-07 15:52:51","AP02SDTM":"2023-01-07 15:52:51","AP02EDTM":"2024-01-07 21:52:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-30","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":499,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.69104,"AVALU":"U/L","BASE2":35.63552,"BASE":21.69104,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-13.94448,"PCHG2":-39.13085,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-04 03:52:51","ADY":209,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-5","SUBJID":"id-5","SITEID":"CHN-17","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.86288,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-04","TRTSDTM":"2021-01-07 03:52:51","TRTEDTM":"2024-01-07 21:52:51","TRT01SDTM":"2021-01-07 03:52:51","TRT01EDTM":"2023-01-07 15:52:51","TRT02SDTM":"2023-01-07 15:52:51","TRT02EDTM":"2024-01-07 21:52:51","AP01SDTM":"2021-01-07 03:52:51","AP01EDTM":"2023-01-07 15:52:51","AP02SDTM":"2023-01-07 15:52:51","AP02EDTM":"2024-01-07 21:52:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-30","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2229,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.26869,"AVALU":"U/L","BASE2":35.63552,"BASE":21.69104,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-33.36683,"PCHG2":-93.63363,"CHG":-19.42235,"PCHG":-89.54089,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2022-04-16 03:52:51","ADY":464,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-5","SUBJID":"id-5","SITEID":"CHN-17","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.86288,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-04","TRTSDTM":"2021-01-07 03:52:51","TRTEDTM":"2024-01-07 21:52:51","TRT01SDTM":"2021-01-07 03:52:51","TRT01EDTM":"2023-01-07 15:52:51","TRT02SDTM":"2023-01-07 15:52:51","TRT02EDTM":"2024-01-07 21:52:51","AP01SDTM":"2021-01-07 03:52:51","AP01EDTM":"2023-01-07 15:52:51","AP02SDTM":"2023-01-07 15:52:51","AP02EDTM":"2024-01-07 21:52:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-30","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1880,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.64252,"AVALU":"U/L","BASE2":35.63552,"BASE":21.69104,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-18.993,"PCHG2":-53.29795,"CHG":-5.04852,"PCHG":-23.27467,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-12 03:52:51","ADY":674,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-5","SUBJID":"id-5","SITEID":"CHN-17","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.86288,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-04","TRTSDTM":"2021-01-07 03:52:51","TRTEDTM":"2024-01-07 21:52:51","TRT01SDTM":"2021-01-07 03:52:51","TRT01EDTM":"2023-01-07 15:52:51","TRT02SDTM":"2023-01-07 15:52:51","TRT02EDTM":"2024-01-07 21:52:51","AP01SDTM":"2021-01-07 03:52:51","AP01EDTM":"2023-01-07 15:52:51","AP02SDTM":"2023-01-07 15:52:51","AP02EDTM":"2024-01-07 21:52:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-30","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4148,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.16859,"AVALU":"U/L","BASE2":35.63552,"BASE":21.69104,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.46693,"PCHG2":-40.59693,"CHG":-0.52244,"PCHG":-2.40857,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-20 03:52:51","ADY":682,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-5","SUBJID":"id-5","SITEID":"CHN-17","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.86288,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-04","TRTSDTM":"2021-01-07 03:52:51","TRTEDTM":"2024-01-07 21:52:51","TRT01SDTM":"2021-01-07 03:52:51","TRT01EDTM":"2023-01-07 15:52:51","TRT02SDTM":"2023-01-07 15:52:51","TRT02EDTM":"2024-01-07 21:52:51","AP01SDTM":"2021-01-07 03:52:51","AP01EDTM":"2023-01-07 15:52:51","AP02SDTM":"2023-01-07 15:52:51","AP02EDTM":"2024-01-07 21:52:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-30","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":424,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.73683,"AVALU":"U/L","BASE2":35.63552,"BASE":21.69104,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-20.89869,"PCHG2":-58.64566,"CHG":-6.9542,"PCHG":-32.06026,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-07 03:52:51","ADY":820,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-5","SUBJID":"id-5","SITEID":"CHN-17","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.86288,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-04","TRTSDTM":"2021-01-07 03:52:51","TRTEDTM":"2024-01-07 21:52:51","TRT01SDTM":"2021-01-07 03:52:51","TRT01EDTM":"2023-01-07 15:52:51","TRT02SDTM":"2023-01-07 15:52:51","TRT02EDTM":"2024-01-07 21:52:51","AP01SDTM":"2021-01-07 03:52:51","AP01EDTM":"2023-01-07 15:52:51","AP02SDTM":"2023-01-07 15:52:51","AP02EDTM":"2024-01-07 21:52:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-30","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":364,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.22561,"AVALU":"U/L","BASE2":35.63552,"BASE":21.69104,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.40991,"PCHG2":-48.85548,"CHG":-3.46542,"PCHG":-15.97629,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-11-11 03:52:51","ADY":1038,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-5","SUBJID":"id-5","SITEID":"CHN-17","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.86288,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-04","TRTSDTM":"2021-01-07 03:52:51","TRTEDTM":"2024-01-07 21:52:51","TRT01SDTM":"2021-01-07 03:52:51","TRT01EDTM":"2023-01-07 15:52:51","TRT02SDTM":"2023-01-07 15:52:51","TRT02EDTM":"2024-01-07 21:52:51","AP01SDTM":"2021-01-07 03:52:51","AP01EDTM":"2023-01-07 15:52:51","AP02SDTM":"2023-01-07 15:52:51","AP02EDTM":"2024-01-07 21:52:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-30","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8070,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.60278,"AVALU":"mg/L","BASE2":10.60278,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"1","ADTM":"2021-04-27 03:52:51","ADY":110,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-5","SUBJID":"id-5","SITEID":"CHN-17","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.86288,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-04","TRTSDTM":"2021-01-07 03:52:51","TRTEDTM":"2024-01-07 21:52:51","TRT01SDTM":"2021-01-07 03:52:51","TRT01EDTM":"2023-01-07 15:52:51","TRT02SDTM":"2023-01-07 15:52:51","TRT02EDTM":"2024-01-07 21:52:51","AP01SDTM":"2021-01-07 03:52:51","AP01EDTM":"2023-01-07 15:52:51","AP02SDTM":"2023-01-07 15:52:51","AP02EDTM":"2024-01-07 21:52:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-30","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8156,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.27093,"AVALU":"mg/L","BASE2":10.60278,"BASE":10.27093,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.33185,"PCHG2":-3.12983,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2021-08-04 03:52:51","ADY":209,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-5","SUBJID":"id-5","SITEID":"CHN-17","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.86288,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-04","TRTSDTM":"2021-01-07 03:52:51","TRTEDTM":"2024-01-07 21:52:51","TRT01SDTM":"2021-01-07 03:52:51","TRT01EDTM":"2023-01-07 15:52:51","TRT02SDTM":"2023-01-07 15:52:51","TRT02EDTM":"2024-01-07 21:52:51","AP01SDTM":"2021-01-07 03:52:51","AP01EDTM":"2023-01-07 15:52:51","AP02SDTM":"2023-01-07 15:52:51","AP02EDTM":"2024-01-07 21:52:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-30","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3003,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.36714,"AVALU":"mg/L","BASE2":10.60278,"BASE":10.27093,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.23565,"PCHG2":-2.22249,"CHG":0.0962,"PCHG":0.93666,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"1","ADTM":"2022-04-16 03:52:51","ADY":464,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-5","SUBJID":"id-5","SITEID":"CHN-17","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.86288,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-04","TRTSDTM":"2021-01-07 03:52:51","TRTEDTM":"2024-01-07 21:52:51","TRT01SDTM":"2021-01-07 03:52:51","TRT01EDTM":"2023-01-07 15:52:51","TRT02SDTM":"2023-01-07 15:52:51","TRT02EDTM":"2024-01-07 21:52:51","AP01SDTM":"2021-01-07 03:52:51","AP01EDTM":"2023-01-07 15:52:51","AP02SDTM":"2023-01-07 15:52:51","AP02EDTM":"2024-01-07 21:52:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-30","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1731,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.69413,"AVALU":"mg/L","BASE2":10.60278,"BASE":10.27093,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09134,"PCHG2":0.86152,"CHG":0.42319,"PCHG":4.12031,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"1","BTOXGR":"1","ADTM":"2022-11-12 03:52:51","ADY":674,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-5","SUBJID":"id-5","SITEID":"CHN-17","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.86288,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-04","TRTSDTM":"2021-01-07 03:52:51","TRTEDTM":"2024-01-07 21:52:51","TRT01SDTM":"2021-01-07 03:52:51","TRT01EDTM":"2023-01-07 15:52:51","TRT02SDTM":"2023-01-07 15:52:51","TRT02EDTM":"2024-01-07 21:52:51","AP01SDTM":"2021-01-07 03:52:51","AP01EDTM":"2023-01-07 15:52:51","AP02SDTM":"2023-01-07 15:52:51","AP02EDTM":"2024-01-07 21:52:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-30","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7350,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.3862,"AVALU":"mg/L","BASE2":10.60278,"BASE":10.27093,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.21659,"PCHG2":-30.33721,"CHG":-2.88474,"PCHG":-28.08643,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-4","BTOXGR":"1","ADTM":"2022-11-20 03:52:51","ADY":682,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-5","SUBJID":"id-5","SITEID":"CHN-17","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.86288,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-04","TRTSDTM":"2021-01-07 03:52:51","TRTEDTM":"2024-01-07 21:52:51","TRT01SDTM":"2021-01-07 03:52:51","TRT01EDTM":"2023-01-07 15:52:51","TRT02SDTM":"2023-01-07 15:52:51","TRT02EDTM":"2024-01-07 21:52:51","AP01SDTM":"2021-01-07 03:52:51","AP01EDTM":"2023-01-07 15:52:51","AP02SDTM":"2023-01-07 15:52:51","AP02EDTM":"2024-01-07 21:52:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-30","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5546,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.53022,"AVALU":"mg/L","BASE2":10.60278,"BASE":10.27093,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07257,"PCHG2":-0.68441,"CHG":0.25928,"PCHG":2.52443,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"1","ADTM":"2023-04-07 03:52:51","ADY":820,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-5","SUBJID":"id-5","SITEID":"CHN-17","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.86288,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-04","TRTSDTM":"2021-01-07 03:52:51","TRTEDTM":"2024-01-07 21:52:51","TRT01SDTM":"2021-01-07 03:52:51","TRT01EDTM":"2023-01-07 15:52:51","TRT02SDTM":"2023-01-07 15:52:51","TRT02EDTM":"2024-01-07 21:52:51","AP01SDTM":"2021-01-07 03:52:51","AP01EDTM":"2023-01-07 15:52:51","AP02SDTM":"2023-01-07 15:52:51","AP02EDTM":"2024-01-07 21:52:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-30","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1260,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.48881,"AVALU":"mg/L","BASE2":10.60278,"BASE":10.27093,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.11397,"PCHG2":-19.93791,"CHG":-1.78212,"PCHG":-17.35114,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2023-11-11 03:52:51","ADY":1038,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-5","SUBJID":"id-5","SITEID":"CHN-17","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.86288,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-04","TRTSDTM":"2021-01-07 03:52:51","TRTEDTM":"2024-01-07 21:52:51","TRT01SDTM":"2021-01-07 03:52:51","TRT01EDTM":"2023-01-07 15:52:51","TRT02SDTM":"2023-01-07 15:52:51","TRT02EDTM":"2024-01-07 21:52:51","AP01SDTM":"2021-01-07 03:52:51","AP01EDTM":"2023-01-07 15:52:51","AP02SDTM":"2023-01-07 15:52:51","AP02EDTM":"2024-01-07 21:52:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-30","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1437,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99184,"AVALU":"g/L","BASE2":2.99184,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-27 03:52:51","ADY":110,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-5","SUBJID":"id-5","SITEID":"CHN-17","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.86288,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-04","TRTSDTM":"2021-01-07 03:52:51","TRTEDTM":"2024-01-07 21:52:51","TRT01SDTM":"2021-01-07 03:52:51","TRT01EDTM":"2023-01-07 15:52:51","TRT02SDTM":"2023-01-07 15:52:51","TRT02EDTM":"2024-01-07 21:52:51","AP01SDTM":"2021-01-07 03:52:51","AP01EDTM":"2023-01-07 15:52:51","AP02SDTM":"2023-01-07 15:52:51","AP02EDTM":"2024-01-07 21:52:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-30","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":296,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96306,"AVALU":"g/L","BASE2":2.99184,"BASE":2.96306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.02878,"PCHG2":-0.9618,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-04 03:52:51","ADY":209,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-5","SUBJID":"id-5","SITEID":"CHN-17","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.86288,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-04","TRTSDTM":"2021-01-07 03:52:51","TRTEDTM":"2024-01-07 21:52:51","TRT01SDTM":"2021-01-07 03:52:51","TRT01EDTM":"2023-01-07 15:52:51","TRT02SDTM":"2023-01-07 15:52:51","TRT02EDTM":"2024-01-07 21:52:51","AP01SDTM":"2021-01-07 03:52:51","AP01EDTM":"2023-01-07 15:52:51","AP02SDTM":"2023-01-07 15:52:51","AP02EDTM":"2024-01-07 21:52:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-30","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1278,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85291,"AVALU":"g/L","BASE2":2.99184,"BASE":2.96306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13892,"PCHG2":-4.64343,"CHG":-0.11015,"PCHG":-3.71739,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-16 03:52:51","ADY":464,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-5","SUBJID":"id-5","SITEID":"CHN-17","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.86288,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-04","TRTSDTM":"2021-01-07 03:52:51","TRTEDTM":"2024-01-07 21:52:51","TRT01SDTM":"2021-01-07 03:52:51","TRT01EDTM":"2023-01-07 15:52:51","TRT02SDTM":"2023-01-07 15:52:51","TRT02EDTM":"2024-01-07 21:52:51","AP01SDTM":"2021-01-07 03:52:51","AP01EDTM":"2023-01-07 15:52:51","AP02SDTM":"2023-01-07 15:52:51","AP02EDTM":"2024-01-07 21:52:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-30","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7209,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97501,"AVALU":"g/L","BASE2":2.99184,"BASE":2.96306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01682,"PCHG2":-0.56234,"CHG":0.01195,"PCHG":0.40334,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-12 03:52:51","ADY":674,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-5","SUBJID":"id-5","SITEID":"CHN-17","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.86288,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-04","TRTSDTM":"2021-01-07 03:52:51","TRTEDTM":"2024-01-07 21:52:51","TRT01SDTM":"2021-01-07 03:52:51","TRT01EDTM":"2023-01-07 15:52:51","TRT02SDTM":"2023-01-07 15:52:51","TRT02EDTM":"2024-01-07 21:52:51","AP01SDTM":"2021-01-07 03:52:51","AP01EDTM":"2023-01-07 15:52:51","AP02SDTM":"2023-01-07 15:52:51","AP02EDTM":"2024-01-07 21:52:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-30","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7063,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78753,"AVALU":"g/L","BASE2":2.99184,"BASE":2.96306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20431,"PCHG2":-6.82896,"CHG":-0.17554,"PCHG":-5.92414,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-20 03:52:51","ADY":682,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-5","SUBJID":"id-5","SITEID":"CHN-17","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.86288,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-04","TRTSDTM":"2021-01-07 03:52:51","TRTEDTM":"2024-01-07 21:52:51","TRT01SDTM":"2021-01-07 03:52:51","TRT01EDTM":"2023-01-07 15:52:51","TRT02SDTM":"2023-01-07 15:52:51","TRT02EDTM":"2024-01-07 21:52:51","AP01SDTM":"2021-01-07 03:52:51","AP01EDTM":"2023-01-07 15:52:51","AP02SDTM":"2023-01-07 15:52:51","AP02EDTM":"2024-01-07 21:52:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-30","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":621,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91437,"AVALU":"g/L","BASE2":2.99184,"BASE":2.96306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07747,"PCHG2":-2.58925,"CHG":-0.04869,"PCHG":-1.64326,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-07 03:52:51","ADY":820,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-5","SUBJID":"id-5","SITEID":"CHN-17","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.86288,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-04","TRTSDTM":"2021-01-07 03:52:51","TRTEDTM":"2024-01-07 21:52:51","TRT01SDTM":"2021-01-07 03:52:51","TRT01EDTM":"2023-01-07 15:52:51","TRT02SDTM":"2023-01-07 15:52:51","TRT02EDTM":"2024-01-07 21:52:51","AP01SDTM":"2021-01-07 03:52:51","AP01EDTM":"2023-01-07 15:52:51","AP02SDTM":"2023-01-07 15:52:51","AP02EDTM":"2024-01-07 21:52:51","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-30","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3484,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89573,"AVALU":"g/L","BASE2":2.99184,"BASE":2.96306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09611,"PCHG2":-3.21231,"CHG":-0.06733,"PCHG":-2.27237,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-11-11 03:52:51","ADY":1038,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-66","SUBJID":"id-66","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.83802,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-27","TRTSDTM":"2019-06-29 23:27:28","TRTEDTM":"2022-02-12 15:00:42","TRT01SDTM":"2019-06-29 23:27:28","TRT01EDTM":"2021-02-12 09:00:42","TRT02SDTM":"2021-02-12 09:00:42","TRT02EDTM":"2022-02-12 15:00:42","AP01SDTM":"2019-06-29 23:27:28","AP01EDTM":"2021-02-12 09:00:42","AP02SDTM":"2021-02-12 09:00:42","AP02EDTM":"2022-02-12 15:00:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":959,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2769,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.64945,"AVALU":"U/L","BASE2":16.64945,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-1","ADTM":"2019-07-10 23:27:28","ADY":11,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-66","SUBJID":"id-66","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.83802,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-27","TRTSDTM":"2019-06-29 23:27:28","TRTEDTM":"2022-02-12 15:00:42","TRT01SDTM":"2019-06-29 23:27:28","TRT01EDTM":"2021-02-12 09:00:42","TRT02SDTM":"2021-02-12 09:00:42","TRT02EDTM":"2022-02-12 15:00:42","AP01SDTM":"2019-06-29 23:27:28","AP01EDTM":"2021-02-12 09:00:42","AP02SDTM":"2021-02-12 09:00:42","AP02EDTM":"2022-02-12 15:00:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":959,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":18,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.87701,"AVALU":"U/L","BASE2":16.64945,"BASE":4.87701,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-11.77244,"PCHG2":-70.70767,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2019-09-17 23:27:28","ADY":80,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-66","SUBJID":"id-66","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.83802,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-27","TRTSDTM":"2019-06-29 23:27:28","TRTEDTM":"2022-02-12 15:00:42","TRT01SDTM":"2019-06-29 23:27:28","TRT01EDTM":"2021-02-12 09:00:42","TRT02SDTM":"2021-02-12 09:00:42","TRT02EDTM":"2022-02-12 15:00:42","AP01SDTM":"2019-06-29 23:27:28","AP01EDTM":"2021-02-12 09:00:42","AP02SDTM":"2021-02-12 09:00:42","AP02EDTM":"2022-02-12 15:00:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":959,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1477,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.39586,"AVALU":"U/L","BASE2":16.64945,"BASE":4.87701,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.74641,"PCHG2":4.48306,"CHG":12.51885,"PCHG":256.69092,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2019-10-04 23:27:28","ADY":97,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-66","SUBJID":"id-66","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.83802,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-27","TRTSDTM":"2019-06-29 23:27:28","TRTEDTM":"2022-02-12 15:00:42","TRT01SDTM":"2019-06-29 23:27:28","TRT01EDTM":"2021-02-12 09:00:42","TRT02SDTM":"2021-02-12 09:00:42","TRT02EDTM":"2022-02-12 15:00:42","AP01SDTM":"2019-06-29 23:27:28","AP01EDTM":"2021-02-12 09:00:42","AP02SDTM":"2021-02-12 09:00:42","AP02EDTM":"2022-02-12 15:00:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":959,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":67,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.56967,"AVALU":"U/L","BASE2":16.64945,"BASE":4.87701,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.92021,"PCHG2":83.60762,"CHG":25.69265,"PCHG":526.81137,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-03-27 23:27:28","ADY":272,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-66","SUBJID":"id-66","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.83802,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-27","TRTSDTM":"2019-06-29 23:27:28","TRTEDTM":"2022-02-12 15:00:42","TRT01SDTM":"2019-06-29 23:27:28","TRT01EDTM":"2021-02-12 09:00:42","TRT02SDTM":"2021-02-12 09:00:42","TRT02EDTM":"2022-02-12 15:00:42","AP01SDTM":"2019-06-29 23:27:28","AP01EDTM":"2021-02-12 09:00:42","AP02SDTM":"2021-02-12 09:00:42","AP02EDTM":"2022-02-12 15:00:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":959,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2271,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.06998,"AVALU":"U/L","BASE2":16.64945,"BASE":4.87701,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.42052,"PCHG2":8.53195,"CHG":13.19296,"PCHG":270.51326,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-07-23 23:27:28","ADY":390,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-66","SUBJID":"id-66","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.83802,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-27","TRTSDTM":"2019-06-29 23:27:28","TRTEDTM":"2022-02-12 15:00:42","TRT01SDTM":"2019-06-29 23:27:28","TRT01EDTM":"2021-02-12 09:00:42","TRT02SDTM":"2021-02-12 09:00:42","TRT02EDTM":"2022-02-12 15:00:42","AP01SDTM":"2019-06-29 23:27:28","AP01EDTM":"2021-02-12 09:00:42","AP02SDTM":"2021-02-12 09:00:42","AP02EDTM":"2022-02-12 15:00:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":959,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1840,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":47.9592,"AVALU":"U/L","BASE2":16.64945,"BASE":4.87701,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":31.30974,"PCHG2":188.05268,"CHG":43.08219,"PCHG":883.37253,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-07-24 23:27:28","ADY":391,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-66","SUBJID":"id-66","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.83802,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-27","TRTSDTM":"2019-06-29 23:27:28","TRTEDTM":"2022-02-12 15:00:42","TRT01SDTM":"2019-06-29 23:27:28","TRT01EDTM":"2021-02-12 09:00:42","TRT02SDTM":"2021-02-12 09:00:42","TRT02EDTM":"2022-02-12 15:00:42","AP01SDTM":"2019-06-29 23:27:28","AP01EDTM":"2021-02-12 09:00:42","AP02SDTM":"2021-02-12 09:00:42","AP02EDTM":"2022-02-12 15:00:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":959,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3821,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.21981,"AVALU":"U/L","BASE2":16.64945,"BASE":4.87701,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.57036,"PCHG2":3.42569,"CHG":12.3428,"PCHG":253.08121,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-10-15 23:27:28","ADY":839,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-66","SUBJID":"id-66","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.83802,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-27","TRTSDTM":"2019-06-29 23:27:28","TRTEDTM":"2022-02-12 15:00:42","TRT01SDTM":"2019-06-29 23:27:28","TRT01EDTM":"2021-02-12 09:00:42","TRT02SDTM":"2021-02-12 09:00:42","TRT02EDTM":"2022-02-12 15:00:42","AP01SDTM":"2019-06-29 23:27:28","AP01EDTM":"2021-02-12 09:00:42","AP02SDTM":"2021-02-12 09:00:42","AP02EDTM":"2022-02-12 15:00:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":959,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5310,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.94408,"AVALU":"mg/L","BASE2":7.94408,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2019-07-10 23:27:28","ADY":11,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-66","SUBJID":"id-66","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.83802,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-27","TRTSDTM":"2019-06-29 23:27:28","TRTEDTM":"2022-02-12 15:00:42","TRT01SDTM":"2019-06-29 23:27:28","TRT01EDTM":"2021-02-12 09:00:42","TRT02SDTM":"2021-02-12 09:00:42","TRT02EDTM":"2022-02-12 15:00:42","AP01SDTM":"2019-06-29 23:27:28","AP01EDTM":"2021-02-12 09:00:42","AP02SDTM":"2021-02-12 09:00:42","AP02EDTM":"2022-02-12 15:00:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":959,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1367,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.33822,"AVALU":"mg/L","BASE2":7.94408,"BASE":9.33822,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.39414,"PCHG2":17.54948,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-17 23:27:28","ADY":80,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-66","SUBJID":"id-66","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.83802,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-27","TRTSDTM":"2019-06-29 23:27:28","TRTEDTM":"2022-02-12 15:00:42","TRT01SDTM":"2019-06-29 23:27:28","TRT01EDTM":"2021-02-12 09:00:42","TRT02SDTM":"2021-02-12 09:00:42","TRT02EDTM":"2022-02-12 15:00:42","AP01SDTM":"2019-06-29 23:27:28","AP01EDTM":"2021-02-12 09:00:42","AP02SDTM":"2021-02-12 09:00:42","AP02EDTM":"2022-02-12 15:00:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":959,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6259,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.1956,"AVALU":"mg/L","BASE2":7.94408,"BASE":9.33822,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.25153,"PCHG2":3.16622,"CHG":-1.14262,"PCHG":-12.23592,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-04 23:27:28","ADY":97,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-66","SUBJID":"id-66","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.83802,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-27","TRTSDTM":"2019-06-29 23:27:28","TRTEDTM":"2022-02-12 15:00:42","TRT01SDTM":"2019-06-29 23:27:28","TRT01EDTM":"2021-02-12 09:00:42","TRT02SDTM":"2021-02-12 09:00:42","TRT02EDTM":"2022-02-12 15:00:42","AP01SDTM":"2019-06-29 23:27:28","AP01EDTM":"2021-02-12 09:00:42","AP02SDTM":"2021-02-12 09:00:42","AP02EDTM":"2022-02-12 15:00:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":959,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6681,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.21974,"AVALU":"mg/L","BASE2":7.94408,"BASE":9.33822,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.27567,"PCHG2":16.05809,"CHG":-0.11848,"PCHG":-1.26874,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-27 23:27:28","ADY":272,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-66","SUBJID":"id-66","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.83802,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-27","TRTSDTM":"2019-06-29 23:27:28","TRTEDTM":"2022-02-12 15:00:42","TRT01SDTM":"2019-06-29 23:27:28","TRT01EDTM":"2021-02-12 09:00:42","TRT02SDTM":"2021-02-12 09:00:42","TRT02EDTM":"2022-02-12 15:00:42","AP01SDTM":"2019-06-29 23:27:28","AP01EDTM":"2021-02-12 09:00:42","AP02SDTM":"2021-02-12 09:00:42","AP02EDTM":"2022-02-12 15:00:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":959,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4768,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.34976,"AVALU":"mg/L","BASE2":7.94408,"BASE":9.33822,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.40569,"PCHG2":30.28277,"CHG":1.01154,"PCHG":10.83227,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-07-23 23:27:28","ADY":390,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-66","SUBJID":"id-66","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.83802,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-27","TRTSDTM":"2019-06-29 23:27:28","TRTEDTM":"2022-02-12 15:00:42","TRT01SDTM":"2019-06-29 23:27:28","TRT01EDTM":"2021-02-12 09:00:42","TRT02SDTM":"2021-02-12 09:00:42","TRT02EDTM":"2022-02-12 15:00:42","AP01SDTM":"2019-06-29 23:27:28","AP01EDTM":"2021-02-12 09:00:42","AP02SDTM":"2021-02-12 09:00:42","AP02EDTM":"2022-02-12 15:00:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":959,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4513,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.35724,"AVALU":"mg/L","BASE2":7.94408,"BASE":9.33822,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.41316,"PCHG2":30.37686,"CHG":1.01902,"PCHG":10.91232,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-07-24 23:27:28","ADY":391,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-66","SUBJID":"id-66","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.83802,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-27","TRTSDTM":"2019-06-29 23:27:28","TRTEDTM":"2022-02-12 15:00:42","TRT01SDTM":"2019-06-29 23:27:28","TRT01EDTM":"2021-02-12 09:00:42","TRT02SDTM":"2021-02-12 09:00:42","TRT02EDTM":"2022-02-12 15:00:42","AP01SDTM":"2019-06-29 23:27:28","AP01EDTM":"2021-02-12 09:00:42","AP02SDTM":"2021-02-12 09:00:42","AP02EDTM":"2022-02-12 15:00:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":959,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7491,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.70968,"AVALU":"mg/L","BASE2":7.94408,"BASE":9.33822,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.7656,"PCHG2":34.81334,"CHG":1.37145,"PCHG":14.68646,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-10-15 23:27:28","ADY":839,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-66","SUBJID":"id-66","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.83802,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-27","TRTSDTM":"2019-06-29 23:27:28","TRTEDTM":"2022-02-12 15:00:42","TRT01SDTM":"2019-06-29 23:27:28","TRT01EDTM":"2021-02-12 09:00:42","TRT02SDTM":"2021-02-12 09:00:42","TRT02EDTM":"2022-02-12 15:00:42","AP01SDTM":"2019-06-29 23:27:28","AP01EDTM":"2021-02-12 09:00:42","AP02SDTM":"2021-02-12 09:00:42","AP02EDTM":"2022-02-12 15:00:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":959,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7153,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93866,"AVALU":"g/L","BASE2":2.93866,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-10 23:27:28","ADY":11,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-66","SUBJID":"id-66","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.83802,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-27","TRTSDTM":"2019-06-29 23:27:28","TRTEDTM":"2022-02-12 15:00:42","TRT01SDTM":"2019-06-29 23:27:28","TRT01EDTM":"2021-02-12 09:00:42","TRT02SDTM":"2021-02-12 09:00:42","TRT02EDTM":"2022-02-12 15:00:42","AP01SDTM":"2019-06-29 23:27:28","AP01EDTM":"2021-02-12 09:00:42","AP02SDTM":"2021-02-12 09:00:42","AP02EDTM":"2022-02-12 15:00:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":959,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7484,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89794,"AVALU":"g/L","BASE2":2.93866,"BASE":2.89794,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.04073,"PCHG2":-1.38594,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-17 23:27:28","ADY":80,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-66","SUBJID":"id-66","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.83802,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-27","TRTSDTM":"2019-06-29 23:27:28","TRTEDTM":"2022-02-12 15:00:42","TRT01SDTM":"2019-06-29 23:27:28","TRT01EDTM":"2021-02-12 09:00:42","TRT02SDTM":"2021-02-12 09:00:42","TRT02EDTM":"2022-02-12 15:00:42","AP01SDTM":"2019-06-29 23:27:28","AP01EDTM":"2021-02-12 09:00:42","AP02SDTM":"2021-02-12 09:00:42","AP02EDTM":"2022-02-12 15:00:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":959,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6504,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.73168,"AVALU":"g/L","BASE2":2.93866,"BASE":2.89794,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20698,"PCHG2":-7.04332,"CHG":-0.16625,"PCHG":-5.73689,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-04 23:27:28","ADY":97,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-66","SUBJID":"id-66","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.83802,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-27","TRTSDTM":"2019-06-29 23:27:28","TRTEDTM":"2022-02-12 15:00:42","TRT01SDTM":"2019-06-29 23:27:28","TRT01EDTM":"2021-02-12 09:00:42","TRT02SDTM":"2021-02-12 09:00:42","TRT02EDTM":"2022-02-12 15:00:42","AP01SDTM":"2019-06-29 23:27:28","AP01EDTM":"2021-02-12 09:00:42","AP02SDTM":"2021-02-12 09:00:42","AP02EDTM":"2022-02-12 15:00:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":959,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3914,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99227,"AVALU":"g/L","BASE2":2.93866,"BASE":2.89794,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0536,"PCHG2":1.82409,"CHG":0.09433,"PCHG":3.25515,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-27 23:27:28","ADY":272,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-66","SUBJID":"id-66","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.83802,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-27","TRTSDTM":"2019-06-29 23:27:28","TRTEDTM":"2022-02-12 15:00:42","TRT01SDTM":"2019-06-29 23:27:28","TRT01EDTM":"2021-02-12 09:00:42","TRT02SDTM":"2021-02-12 09:00:42","TRT02EDTM":"2022-02-12 15:00:42","AP01SDTM":"2019-06-29 23:27:28","AP01EDTM":"2021-02-12 09:00:42","AP02SDTM":"2021-02-12 09:00:42","AP02EDTM":"2022-02-12 15:00:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":959,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3853,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0767,"AVALU":"g/L","BASE2":2.93866,"BASE":2.89794,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13803,"PCHG2":4.69711,"CHG":0.17876,"PCHG":6.16854,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-07-23 23:27:28","ADY":390,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-66","SUBJID":"id-66","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.83802,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-27","TRTSDTM":"2019-06-29 23:27:28","TRTEDTM":"2022-02-12 15:00:42","TRT01SDTM":"2019-06-29 23:27:28","TRT01EDTM":"2021-02-12 09:00:42","TRT02SDTM":"2021-02-12 09:00:42","TRT02EDTM":"2022-02-12 15:00:42","AP01SDTM":"2019-06-29 23:27:28","AP01EDTM":"2021-02-12 09:00:42","AP02SDTM":"2021-02-12 09:00:42","AP02EDTM":"2022-02-12 15:00:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":959,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7751,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89622,"AVALU":"g/L","BASE2":2.93866,"BASE":2.89794,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04244,"PCHG2":-1.44427,"CHG":-0.00171,"PCHG":-0.05915,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-24 23:27:28","ADY":391,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-66","SUBJID":"id-66","SITEID":"CHN-17","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.83802,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-27","TRTSDTM":"2019-06-29 23:27:28","TRTEDTM":"2022-02-12 15:00:42","TRT01SDTM":"2019-06-29 23:27:28","TRT01EDTM":"2021-02-12 09:00:42","TRT02SDTM":"2021-02-12 09:00:42","TRT02EDTM":"2022-02-12 15:00:42","AP01SDTM":"2019-06-29 23:27:28","AP01EDTM":"2021-02-12 09:00:42","AP02SDTM":"2021-02-12 09:00:42","AP02EDTM":"2022-02-12 15:00:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":959,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-11","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6798,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.65629,"AVALU":"g/L","BASE2":2.93866,"BASE":2.89794,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.28237,"PCHG2":-9.60885,"CHG":-0.24164,"PCHG":-8.33847,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-15 23:27:28","ADY":839,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-84","SUBJID":"id-84","SITEID":"CHN-17","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":6.61367,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-23","TRTSDTM":"2019-03-24 10:21:04","TRTEDTM":"2022-03-24 04:21:04","TRT01SDTM":"2019-03-24 10:21:04","TRT01EDTM":"2021-03-23 22:21:04","TRT02SDTM":"2021-03-23 22:21:04","TRT02EDTM":"2022-03-24 04:21:04","AP01SDTM":"2019-03-24 10:21:04","AP01EDTM":"2021-03-23 22:21:04","AP02SDTM":"2021-03-23 22:21:04","AP02EDTM":"2022-03-24 04:21:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-24","EOSDY":1096,"LSTALVDT":"2022-04-21","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6351,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.55066,"AVALU":"U/L","BASE2":17.55066,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-23 10:21:04","ADY":152,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-84","SUBJID":"id-84","SITEID":"CHN-17","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":6.61367,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-23","TRTSDTM":"2019-03-24 10:21:04","TRTEDTM":"2022-03-24 04:21:04","TRT01SDTM":"2019-03-24 10:21:04","TRT01EDTM":"2021-03-23 22:21:04","TRT02SDTM":"2021-03-23 22:21:04","TRT02EDTM":"2022-03-24 04:21:04","AP01SDTM":"2019-03-24 10:21:04","AP01EDTM":"2021-03-23 22:21:04","AP02SDTM":"2021-03-23 22:21:04","AP02EDTM":"2022-03-24 04:21:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-24","EOSDY":1096,"LSTALVDT":"2022-04-21","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1106,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.39774,"AVALU":"U/L","BASE2":17.55066,"BASE":27.39774,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":9.84707,"PCHG2":56.10656,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-26 10:21:04","ADY":429,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-84","SUBJID":"id-84","SITEID":"CHN-17","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":6.61367,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-23","TRTSDTM":"2019-03-24 10:21:04","TRTEDTM":"2022-03-24 04:21:04","TRT01SDTM":"2019-03-24 10:21:04","TRT01EDTM":"2021-03-23 22:21:04","TRT02SDTM":"2021-03-23 22:21:04","TRT02EDTM":"2022-03-24 04:21:04","AP01SDTM":"2019-03-24 10:21:04","AP01EDTM":"2021-03-23 22:21:04","AP02SDTM":"2021-03-23 22:21:04","AP02EDTM":"2022-03-24 04:21:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-24","EOSDY":1096,"LSTALVDT":"2022-04-21","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7493,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":36.27628,"AVALU":"U/L","BASE2":17.55066,"BASE":27.39774,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.72561,"PCHG2":106.69462,"CHG":8.87854,"PCHG":32.40611,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-17 10:21:04","ADY":573,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-84","SUBJID":"id-84","SITEID":"CHN-17","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":6.61367,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-23","TRTSDTM":"2019-03-24 10:21:04","TRTEDTM":"2022-03-24 04:21:04","TRT01SDTM":"2019-03-24 10:21:04","TRT01EDTM":"2021-03-23 22:21:04","TRT02SDTM":"2021-03-23 22:21:04","TRT02EDTM":"2022-03-24 04:21:04","AP01SDTM":"2019-03-24 10:21:04","AP01EDTM":"2021-03-23 22:21:04","AP02SDTM":"2021-03-23 22:21:04","AP02EDTM":"2022-03-24 04:21:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-24","EOSDY":1096,"LSTALVDT":"2022-04-21","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6454,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.68331,"AVALU":"U/L","BASE2":17.55066,"BASE":27.39774,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.86735,"PCHG2":-73.31549,"CHG":-22.71443,"PCHG":-82.90622,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-11-24 10:21:04","ADY":611,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-84","SUBJID":"id-84","SITEID":"CHN-17","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":6.61367,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-23","TRTSDTM":"2019-03-24 10:21:04","TRTEDTM":"2022-03-24 04:21:04","TRT01SDTM":"2019-03-24 10:21:04","TRT01EDTM":"2021-03-23 22:21:04","TRT02SDTM":"2021-03-23 22:21:04","TRT02EDTM":"2022-03-24 04:21:04","AP01SDTM":"2019-03-24 10:21:04","AP01EDTM":"2021-03-23 22:21:04","AP02SDTM":"2021-03-23 22:21:04","AP02EDTM":"2022-03-24 04:21:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-24","EOSDY":1096,"LSTALVDT":"2022-04-21","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6442,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.69891,"AVALU":"U/L","BASE2":17.55066,"BASE":27.39774,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.85175,"PCHG2":-50.43541,"CHG":-18.69882,"PCHG":-68.24952,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-08 10:21:04","ADY":807,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-84","SUBJID":"id-84","SITEID":"CHN-17","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":6.61367,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-23","TRTSDTM":"2019-03-24 10:21:04","TRTEDTM":"2022-03-24 04:21:04","TRT01SDTM":"2019-03-24 10:21:04","TRT01EDTM":"2021-03-23 22:21:04","TRT02SDTM":"2021-03-23 22:21:04","TRT02EDTM":"2022-03-24 04:21:04","AP01SDTM":"2019-03-24 10:21:04","AP01EDTM":"2021-03-23 22:21:04","AP02SDTM":"2021-03-23 22:21:04","AP02EDTM":"2022-03-24 04:21:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-24","EOSDY":1096,"LSTALVDT":"2022-04-21","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7665,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.15696,"AVALU":"U/L","BASE2":17.55066,"BASE":27.39774,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.60629,"PCHG2":77.52579,"CHG":3.75922,"PCHG":13.72091,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-04 10:21:04","ADY":986,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-84","SUBJID":"id-84","SITEID":"CHN-17","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":6.61367,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-23","TRTSDTM":"2019-03-24 10:21:04","TRTEDTM":"2022-03-24 04:21:04","TRT01SDTM":"2019-03-24 10:21:04","TRT01EDTM":"2021-03-23 22:21:04","TRT02SDTM":"2021-03-23 22:21:04","TRT02EDTM":"2022-03-24 04:21:04","AP01SDTM":"2019-03-24 10:21:04","AP01EDTM":"2021-03-23 22:21:04","AP02SDTM":"2021-03-23 22:21:04","AP02EDTM":"2022-03-24 04:21:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-24","EOSDY":1096,"LSTALVDT":"2022-04-21","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6290,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.27519,"AVALU":"U/L","BASE2":17.55066,"BASE":27.39774,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.27547,"PCHG2":-98.432,"CHG":-27.12254,"PCHG":-98.99556,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-01-12 10:21:04","ADY":1025,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-84","SUBJID":"id-84","SITEID":"CHN-17","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":6.61367,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-23","TRTSDTM":"2019-03-24 10:21:04","TRTEDTM":"2022-03-24 04:21:04","TRT01SDTM":"2019-03-24 10:21:04","TRT01EDTM":"2021-03-23 22:21:04","TRT02SDTM":"2021-03-23 22:21:04","TRT02EDTM":"2022-03-24 04:21:04","AP01SDTM":"2019-03-24 10:21:04","AP01EDTM":"2021-03-23 22:21:04","AP02SDTM":"2021-03-23 22:21:04","AP02EDTM":"2022-03-24 04:21:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-24","EOSDY":1096,"LSTALVDT":"2022-04-21","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5668,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.155,"AVALU":"mg/L","BASE2":10.155,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2019-08-23 10:21:04","ADY":152,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-84","SUBJID":"id-84","SITEID":"CHN-17","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":6.61367,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-23","TRTSDTM":"2019-03-24 10:21:04","TRTEDTM":"2022-03-24 04:21:04","TRT01SDTM":"2019-03-24 10:21:04","TRT01EDTM":"2021-03-23 22:21:04","TRT02SDTM":"2021-03-23 22:21:04","TRT02EDTM":"2022-03-24 04:21:04","AP01SDTM":"2019-03-24 10:21:04","AP01EDTM":"2021-03-23 22:21:04","AP02SDTM":"2021-03-23 22:21:04","AP02EDTM":"2022-03-24 04:21:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-24","EOSDY":1096,"LSTALVDT":"2022-04-21","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":940,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.91978,"AVALU":"mg/L","BASE2":10.155,"BASE":8.91978,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.23522,"PCHG2":-12.16365,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-26 10:21:04","ADY":429,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-84","SUBJID":"id-84","SITEID":"CHN-17","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":6.61367,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-23","TRTSDTM":"2019-03-24 10:21:04","TRTEDTM":"2022-03-24 04:21:04","TRT01SDTM":"2019-03-24 10:21:04","TRT01EDTM":"2021-03-23 22:21:04","TRT02SDTM":"2021-03-23 22:21:04","TRT02EDTM":"2022-03-24 04:21:04","AP01SDTM":"2019-03-24 10:21:04","AP01EDTM":"2021-03-23 22:21:04","AP02SDTM":"2021-03-23 22:21:04","AP02EDTM":"2022-03-24 04:21:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-24","EOSDY":1096,"LSTALVDT":"2022-04-21","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1023,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.82454,"AVALU":"mg/L","BASE2":10.155,"BASE":8.91978,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.33046,"PCHG2":-3.25413,"CHG":0.90476,"PCHG":10.14331,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-17 10:21:04","ADY":573,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-84","SUBJID":"id-84","SITEID":"CHN-17","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":6.61367,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-23","TRTSDTM":"2019-03-24 10:21:04","TRTEDTM":"2022-03-24 04:21:04","TRT01SDTM":"2019-03-24 10:21:04","TRT01EDTM":"2021-03-23 22:21:04","TRT02SDTM":"2021-03-23 22:21:04","TRT02EDTM":"2022-03-24 04:21:04","AP01SDTM":"2019-03-24 10:21:04","AP01EDTM":"2021-03-23 22:21:04","AP02SDTM":"2021-03-23 22:21:04","AP02EDTM":"2022-03-24 04:21:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-24","EOSDY":1096,"LSTALVDT":"2022-04-21","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6741,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.82377,"AVALU":"mg/L","BASE2":10.155,"BASE":8.91978,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.33122,"PCHG2":-3.26169,"CHG":0.90399,"PCHG":10.13471,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-24 10:21:04","ADY":611,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-84","SUBJID":"id-84","SITEID":"CHN-17","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":6.61367,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-23","TRTSDTM":"2019-03-24 10:21:04","TRTEDTM":"2022-03-24 04:21:04","TRT01SDTM":"2019-03-24 10:21:04","TRT01EDTM":"2021-03-23 22:21:04","TRT02SDTM":"2021-03-23 22:21:04","TRT02EDTM":"2022-03-24 04:21:04","AP01SDTM":"2019-03-24 10:21:04","AP01EDTM":"2021-03-23 22:21:04","AP02SDTM":"2021-03-23 22:21:04","AP02EDTM":"2022-03-24 04:21:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-24","EOSDY":1096,"LSTALVDT":"2022-04-21","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1259,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.59993,"AVALU":"mg/L","BASE2":10.155,"BASE":8.91978,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.55507,"PCHG2":-15.31331,"CHG":-0.31985,"PCHG":-3.58583,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-08 10:21:04","ADY":807,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-84","SUBJID":"id-84","SITEID":"CHN-17","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":6.61367,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-23","TRTSDTM":"2019-03-24 10:21:04","TRTEDTM":"2022-03-24 04:21:04","TRT01SDTM":"2019-03-24 10:21:04","TRT01EDTM":"2021-03-23 22:21:04","TRT02SDTM":"2021-03-23 22:21:04","TRT02EDTM":"2022-03-24 04:21:04","AP01SDTM":"2019-03-24 10:21:04","AP01EDTM":"2021-03-23 22:21:04","AP02SDTM":"2021-03-23 22:21:04","AP02EDTM":"2022-03-24 04:21:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-24","EOSDY":1096,"LSTALVDT":"2022-04-21","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3966,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.9372,"AVALU":"mg/L","BASE2":10.155,"BASE":8.91978,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.2178,"PCHG2":-11.99214,"CHG":0.01742,"PCHG":0.19525,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-04 10:21:04","ADY":986,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-84","SUBJID":"id-84","SITEID":"CHN-17","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":6.61367,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-23","TRTSDTM":"2019-03-24 10:21:04","TRTEDTM":"2022-03-24 04:21:04","TRT01SDTM":"2019-03-24 10:21:04","TRT01EDTM":"2021-03-23 22:21:04","TRT02SDTM":"2021-03-23 22:21:04","TRT02EDTM":"2022-03-24 04:21:04","AP01SDTM":"2019-03-24 10:21:04","AP01EDTM":"2021-03-23 22:21:04","AP02SDTM":"2021-03-23 22:21:04","AP02EDTM":"2022-03-24 04:21:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-24","EOSDY":1096,"LSTALVDT":"2022-04-21","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5036,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.55465,"AVALU":"mg/L","BASE2":10.155,"BASE":8.91978,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.60034,"PCHG2":-5.91179,"CHG":0.63488,"PCHG":7.11762,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-12 10:21:04","ADY":1025,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-84","SUBJID":"id-84","SITEID":"CHN-17","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":6.61367,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-23","TRTSDTM":"2019-03-24 10:21:04","TRTEDTM":"2022-03-24 04:21:04","TRT01SDTM":"2019-03-24 10:21:04","TRT01EDTM":"2021-03-23 22:21:04","TRT02SDTM":"2021-03-23 22:21:04","TRT02EDTM":"2022-03-24 04:21:04","AP01SDTM":"2019-03-24 10:21:04","AP01EDTM":"2021-03-23 22:21:04","AP02SDTM":"2021-03-23 22:21:04","AP02EDTM":"2022-03-24 04:21:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-24","EOSDY":1096,"LSTALVDT":"2022-04-21","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7424,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75226,"AVALU":"g/L","BASE2":2.75226,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-23 10:21:04","ADY":152,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-84","SUBJID":"id-84","SITEID":"CHN-17","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":6.61367,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-23","TRTSDTM":"2019-03-24 10:21:04","TRTEDTM":"2022-03-24 04:21:04","TRT01SDTM":"2019-03-24 10:21:04","TRT01EDTM":"2021-03-23 22:21:04","TRT02SDTM":"2021-03-23 22:21:04","TRT02EDTM":"2022-03-24 04:21:04","AP01SDTM":"2019-03-24 10:21:04","AP01EDTM":"2021-03-23 22:21:04","AP02SDTM":"2021-03-23 22:21:04","AP02EDTM":"2022-03-24 04:21:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-24","EOSDY":1096,"LSTALVDT":"2022-04-21","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3323,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92908,"AVALU":"g/L","BASE2":2.75226,"BASE":2.92908,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.17682,"PCHG2":6.42455,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-26 10:21:04","ADY":429,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-84","SUBJID":"id-84","SITEID":"CHN-17","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":6.61367,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-23","TRTSDTM":"2019-03-24 10:21:04","TRTEDTM":"2022-03-24 04:21:04","TRT01SDTM":"2019-03-24 10:21:04","TRT01EDTM":"2021-03-23 22:21:04","TRT02SDTM":"2021-03-23 22:21:04","TRT02EDTM":"2022-03-24 04:21:04","AP01SDTM":"2019-03-24 10:21:04","AP01EDTM":"2021-03-23 22:21:04","AP02SDTM":"2021-03-23 22:21:04","AP02EDTM":"2022-03-24 04:21:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-24","EOSDY":1096,"LSTALVDT":"2022-04-21","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7414,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87295,"AVALU":"g/L","BASE2":2.75226,"BASE":2.92908,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12069,"PCHG2":4.38521,"CHG":-0.05613,"PCHG":-1.91623,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-17 10:21:04","ADY":573,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-84","SUBJID":"id-84","SITEID":"CHN-17","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":6.61367,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-23","TRTSDTM":"2019-03-24 10:21:04","TRTEDTM":"2022-03-24 04:21:04","TRT01SDTM":"2019-03-24 10:21:04","TRT01EDTM":"2021-03-23 22:21:04","TRT02SDTM":"2021-03-23 22:21:04","TRT02EDTM":"2022-03-24 04:21:04","AP01SDTM":"2019-03-24 10:21:04","AP01EDTM":"2021-03-23 22:21:04","AP02SDTM":"2021-03-23 22:21:04","AP02EDTM":"2022-03-24 04:21:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-24","EOSDY":1096,"LSTALVDT":"2022-04-21","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4266,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92285,"AVALU":"g/L","BASE2":2.75226,"BASE":2.92908,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17059,"PCHG2":6.19821,"CHG":-0.00623,"PCHG":-0.21267,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-24 10:21:04","ADY":611,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-84","SUBJID":"id-84","SITEID":"CHN-17","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":6.61367,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-23","TRTSDTM":"2019-03-24 10:21:04","TRTEDTM":"2022-03-24 04:21:04","TRT01SDTM":"2019-03-24 10:21:04","TRT01EDTM":"2021-03-23 22:21:04","TRT02SDTM":"2021-03-23 22:21:04","TRT02EDTM":"2022-03-24 04:21:04","AP01SDTM":"2019-03-24 10:21:04","AP01EDTM":"2021-03-23 22:21:04","AP02SDTM":"2021-03-23 22:21:04","AP02EDTM":"2022-03-24 04:21:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-24","EOSDY":1096,"LSTALVDT":"2022-04-21","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3522,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94916,"AVALU":"g/L","BASE2":2.75226,"BASE":2.92908,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1969,"PCHG2":7.15431,"CHG":0.02008,"PCHG":0.68571,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-08 10:21:04","ADY":807,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-84","SUBJID":"id-84","SITEID":"CHN-17","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":6.61367,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-23","TRTSDTM":"2019-03-24 10:21:04","TRTEDTM":"2022-03-24 04:21:04","TRT01SDTM":"2019-03-24 10:21:04","TRT01EDTM":"2021-03-23 22:21:04","TRT02SDTM":"2021-03-23 22:21:04","TRT02EDTM":"2022-03-24 04:21:04","AP01SDTM":"2019-03-24 10:21:04","AP01EDTM":"2021-03-23 22:21:04","AP02SDTM":"2021-03-23 22:21:04","AP02EDTM":"2022-03-24 04:21:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-24","EOSDY":1096,"LSTALVDT":"2022-04-21","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2815,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74044,"AVALU":"g/L","BASE2":2.75226,"BASE":2.92908,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01181,"PCHG2":-0.42916,"CHG":-0.18863,"PCHG":-6.43997,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-04 10:21:04","ADY":986,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-84","SUBJID":"id-84","SITEID":"CHN-17","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":6.61367,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-23","TRTSDTM":"2019-03-24 10:21:04","TRTEDTM":"2022-03-24 04:21:04","TRT01SDTM":"2019-03-24 10:21:04","TRT01EDTM":"2021-03-23 22:21:04","TRT02SDTM":"2021-03-23 22:21:04","TRT02EDTM":"2022-03-24 04:21:04","AP01SDTM":"2019-03-24 10:21:04","AP01EDTM":"2021-03-23 22:21:04","AP02SDTM":"2021-03-23 22:21:04","AP02EDTM":"2022-03-24 04:21:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-24","EOSDY":1096,"LSTALVDT":"2022-04-21","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6684,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93512,"AVALU":"g/L","BASE2":2.75226,"BASE":2.92908,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18286,"PCHG2":6.64412,"CHG":0.00604,"PCHG":0.20632,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-12 10:21:04","ADY":1025,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-92","SUBJID":"id-92","SITEID":"CHN-17","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.8508,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-01 23:06:08","TRTEDTM":"2022-02-19 01:48:21","TRT01SDTM":"2020-03-01 23:06:08","TRT01EDTM":"2021-02-18 19:48:21","TRT02SDTM":"2021-02-18 19:48:21","TRT02EDTM":"2022-02-19 01:48:21","AP01SDTM":"2020-03-01 23:06:08","AP01EDTM":"2021-02-18 19:48:21","AP02SDTM":"2021-02-18 19:48:21","AP02EDTM":"2022-02-19 01:48:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":720,"DCSREAS":"DEATH","DTHDT":"2022-02-21","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":2,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-21","DTHADY":721,"ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":590,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.10108,"AVALU":"U/L","BASE2":23.10108,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-04 23:06:08","ADY":34,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-92","SUBJID":"id-92","SITEID":"CHN-17","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.8508,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-01 23:06:08","TRTEDTM":"2022-02-19 01:48:21","TRT01SDTM":"2020-03-01 23:06:08","TRT01EDTM":"2021-02-18 19:48:21","TRT02SDTM":"2021-02-18 19:48:21","TRT02EDTM":"2022-02-19 01:48:21","AP01SDTM":"2020-03-01 23:06:08","AP01EDTM":"2021-02-18 19:48:21","AP02SDTM":"2021-02-18 19:48:21","AP02EDTM":"2022-02-19 01:48:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":720,"DCSREAS":"DEATH","DTHDT":"2022-02-21","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":2,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-21","DTHADY":721,"ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6702,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.32618,"AVALU":"U/L","BASE2":23.10108,"BASE":11.32618,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-11.7749,"PCHG2":-50.97121,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-03 23:06:08","ADY":63,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-92","SUBJID":"id-92","SITEID":"CHN-17","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.8508,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-01 23:06:08","TRTEDTM":"2022-02-19 01:48:21","TRT01SDTM":"2020-03-01 23:06:08","TRT01EDTM":"2021-02-18 19:48:21","TRT02SDTM":"2021-02-18 19:48:21","TRT02EDTM":"2022-02-19 01:48:21","AP01SDTM":"2020-03-01 23:06:08","AP01EDTM":"2021-02-18 19:48:21","AP02SDTM":"2021-02-18 19:48:21","AP02EDTM":"2022-02-19 01:48:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":720,"DCSREAS":"DEATH","DTHDT":"2022-02-21","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":2,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-21","DTHADY":721,"ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3087,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.06157,"AVALU":"U/L","BASE2":23.10108,"BASE":11.32618,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.03952,"PCHG2":-52.11667,"CHG":-0.26461,"PCHG":-2.3363,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-30 23:06:08","ADY":151,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-92","SUBJID":"id-92","SITEID":"CHN-17","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.8508,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-01 23:06:08","TRTEDTM":"2022-02-19 01:48:21","TRT01SDTM":"2020-03-01 23:06:08","TRT01EDTM":"2021-02-18 19:48:21","TRT02SDTM":"2021-02-18 19:48:21","TRT02EDTM":"2022-02-19 01:48:21","AP01SDTM":"2020-03-01 23:06:08","AP01EDTM":"2021-02-18 19:48:21","AP02SDTM":"2021-02-18 19:48:21","AP02EDTM":"2022-02-19 01:48:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":720,"DCSREAS":"DEATH","DTHDT":"2022-02-21","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":2,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-21","DTHADY":721,"ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1230,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.47418,"AVALU":"U/L","BASE2":23.10108,"BASE":11.32618,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.6269,"PCHG2":-76.30335,"CHG":-5.852,"PCHG":-51.66788,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-08-15 23:06:08","ADY":167,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-92","SUBJID":"id-92","SITEID":"CHN-17","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.8508,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-01 23:06:08","TRTEDTM":"2022-02-19 01:48:21","TRT01SDTM":"2020-03-01 23:06:08","TRT01EDTM":"2021-02-18 19:48:21","TRT02SDTM":"2021-02-18 19:48:21","TRT02EDTM":"2022-02-19 01:48:21","AP01SDTM":"2020-03-01 23:06:08","AP01EDTM":"2021-02-18 19:48:21","AP02SDTM":"2021-02-18 19:48:21","AP02EDTM":"2022-02-19 01:48:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":720,"DCSREAS":"DEATH","DTHDT":"2022-02-21","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":2,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-21","DTHADY":721,"ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7496,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.89861,"AVALU":"U/L","BASE2":23.10108,"BASE":11.32618,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.20248,"PCHG2":-26.84929,"CHG":5.57242,"PCHG":49.19949,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-30 23:06:08","ADY":213,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-92","SUBJID":"id-92","SITEID":"CHN-17","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.8508,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-01 23:06:08","TRTEDTM":"2022-02-19 01:48:21","TRT01SDTM":"2020-03-01 23:06:08","TRT01EDTM":"2021-02-18 19:48:21","TRT02SDTM":"2021-02-18 19:48:21","TRT02EDTM":"2022-02-19 01:48:21","AP01SDTM":"2020-03-01 23:06:08","AP01EDTM":"2021-02-18 19:48:21","AP02SDTM":"2021-02-18 19:48:21","AP02EDTM":"2022-02-19 01:48:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":720,"DCSREAS":"DEATH","DTHDT":"2022-02-21","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":2,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-21","DTHADY":721,"ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2606,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.84922,"AVALU":"U/L","BASE2":23.10108,"BASE":11.32618,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.74814,"PCHG2":7.56735,"CHG":13.52304,"PCHG":119.3963,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-25 23:06:08","ADY":420,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-92","SUBJID":"id-92","SITEID":"CHN-17","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.8508,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-01 23:06:08","TRTEDTM":"2022-02-19 01:48:21","TRT01SDTM":"2020-03-01 23:06:08","TRT01EDTM":"2021-02-18 19:48:21","TRT02SDTM":"2021-02-18 19:48:21","TRT02EDTM":"2022-02-19 01:48:21","AP01SDTM":"2020-03-01 23:06:08","AP01EDTM":"2021-02-18 19:48:21","AP02SDTM":"2021-02-18 19:48:21","AP02EDTM":"2022-02-19 01:48:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":720,"DCSREAS":"DEATH","DTHDT":"2022-02-21","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":2,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-21","DTHADY":721,"ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3095,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.24747,"AVALU":"U/L","BASE2":23.10108,"BASE":11.32618,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.85362,"PCHG2":-16.68155,"CHG":7.92128,"PCHG":69.93781,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-27 23:06:08","ADY":513,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-92","SUBJID":"id-92","SITEID":"CHN-17","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.8508,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-01 23:06:08","TRTEDTM":"2022-02-19 01:48:21","TRT01SDTM":"2020-03-01 23:06:08","TRT01EDTM":"2021-02-18 19:48:21","TRT02SDTM":"2021-02-18 19:48:21","TRT02EDTM":"2022-02-19 01:48:21","AP01SDTM":"2020-03-01 23:06:08","AP01EDTM":"2021-02-18 19:48:21","AP02SDTM":"2021-02-18 19:48:21","AP02EDTM":"2022-02-19 01:48:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":720,"DCSREAS":"DEATH","DTHDT":"2022-02-21","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":2,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-21","DTHADY":721,"ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1245,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.24576,"AVALU":"mg/L","BASE2":9.24576,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-04 23:06:08","ADY":34,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-92","SUBJID":"id-92","SITEID":"CHN-17","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.8508,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-01 23:06:08","TRTEDTM":"2022-02-19 01:48:21","TRT01SDTM":"2020-03-01 23:06:08","TRT01EDTM":"2021-02-18 19:48:21","TRT02SDTM":"2021-02-18 19:48:21","TRT02EDTM":"2022-02-19 01:48:21","AP01SDTM":"2020-03-01 23:06:08","AP01EDTM":"2021-02-18 19:48:21","AP02SDTM":"2021-02-18 19:48:21","AP02EDTM":"2022-02-19 01:48:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":720,"DCSREAS":"DEATH","DTHDT":"2022-02-21","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":2,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-21","DTHADY":721,"ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1424,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.08281,"AVALU":"mg/L","BASE2":9.24576,"BASE":9.08281,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.16294,"PCHG2":-1.76237,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-03 23:06:08","ADY":63,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-92","SUBJID":"id-92","SITEID":"CHN-17","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.8508,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-01 23:06:08","TRTEDTM":"2022-02-19 01:48:21","TRT01SDTM":"2020-03-01 23:06:08","TRT01EDTM":"2021-02-18 19:48:21","TRT02SDTM":"2021-02-18 19:48:21","TRT02EDTM":"2022-02-19 01:48:21","AP01SDTM":"2020-03-01 23:06:08","AP01EDTM":"2021-02-18 19:48:21","AP02SDTM":"2021-02-18 19:48:21","AP02EDTM":"2022-02-19 01:48:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":720,"DCSREAS":"DEATH","DTHDT":"2022-02-21","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":2,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-21","DTHADY":721,"ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4213,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.61685,"AVALU":"mg/L","BASE2":9.24576,"BASE":9.08281,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.37109,"PCHG2":14.82943,"CHG":1.53404,"PCHG":16.88945,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-07-30 23:06:08","ADY":151,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-92","SUBJID":"id-92","SITEID":"CHN-17","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.8508,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-01 23:06:08","TRTEDTM":"2022-02-19 01:48:21","TRT01SDTM":"2020-03-01 23:06:08","TRT01EDTM":"2021-02-18 19:48:21","TRT02SDTM":"2021-02-18 19:48:21","TRT02EDTM":"2022-02-19 01:48:21","AP01SDTM":"2020-03-01 23:06:08","AP01EDTM":"2021-02-18 19:48:21","AP02SDTM":"2021-02-18 19:48:21","AP02EDTM":"2022-02-19 01:48:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":720,"DCSREAS":"DEATH","DTHDT":"2022-02-21","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":2,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-21","DTHADY":721,"ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1822,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.56397,"AVALU":"mg/L","BASE2":9.24576,"BASE":9.08281,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.68178,"PCHG2":-18.18979,"CHG":-1.51884,"PCHG":-16.72212,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-08-15 23:06:08","ADY":167,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-92","SUBJID":"id-92","SITEID":"CHN-17","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.8508,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-01 23:06:08","TRTEDTM":"2022-02-19 01:48:21","TRT01SDTM":"2020-03-01 23:06:08","TRT01EDTM":"2021-02-18 19:48:21","TRT02SDTM":"2021-02-18 19:48:21","TRT02EDTM":"2022-02-19 01:48:21","AP01SDTM":"2020-03-01 23:06:08","AP01EDTM":"2021-02-18 19:48:21","AP02SDTM":"2021-02-18 19:48:21","AP02EDTM":"2022-02-19 01:48:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":720,"DCSREAS":"DEATH","DTHDT":"2022-02-21","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":2,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-21","DTHADY":721,"ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7286,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.79161,"AVALU":"mg/L","BASE2":9.24576,"BASE":9.08281,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.45415,"PCHG2":-4.91201,"CHG":-0.29121,"PCHG":-3.20614,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-30 23:06:08","ADY":213,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-92","SUBJID":"id-92","SITEID":"CHN-17","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.8508,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-01 23:06:08","TRTEDTM":"2022-02-19 01:48:21","TRT01SDTM":"2020-03-01 23:06:08","TRT01EDTM":"2021-02-18 19:48:21","TRT02SDTM":"2021-02-18 19:48:21","TRT02EDTM":"2022-02-19 01:48:21","AP01SDTM":"2020-03-01 23:06:08","AP01EDTM":"2021-02-18 19:48:21","AP02SDTM":"2021-02-18 19:48:21","AP02EDTM":"2022-02-19 01:48:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":720,"DCSREAS":"DEATH","DTHDT":"2022-02-21","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":2,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-21","DTHADY":721,"ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2045,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":12.21519,"AVALU":"mg/L","BASE2":9.24576,"BASE":9.08281,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.96943,"PCHG2":32.11666,"CHG":3.13237,"PCHG":34.48681,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-04-25 23:06:08","ADY":420,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-92","SUBJID":"id-92","SITEID":"CHN-17","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.8508,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-01 23:06:08","TRTEDTM":"2022-02-19 01:48:21","TRT01SDTM":"2020-03-01 23:06:08","TRT01EDTM":"2021-02-18 19:48:21","TRT02SDTM":"2021-02-18 19:48:21","TRT02EDTM":"2022-02-19 01:48:21","AP01SDTM":"2020-03-01 23:06:08","AP01EDTM":"2021-02-18 19:48:21","AP02SDTM":"2021-02-18 19:48:21","AP02EDTM":"2022-02-19 01:48:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":720,"DCSREAS":"DEATH","DTHDT":"2022-02-21","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":2,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-21","DTHADY":721,"ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3122,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.99427,"AVALU":"mg/L","BASE2":9.24576,"BASE":9.08281,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.25149,"PCHG2":-2.72001,"CHG":-0.08854,"PCHG":-0.97482,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-27 23:06:08","ADY":513,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-92","SUBJID":"id-92","SITEID":"CHN-17","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.8508,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-01 23:06:08","TRTEDTM":"2022-02-19 01:48:21","TRT01SDTM":"2020-03-01 23:06:08","TRT01EDTM":"2021-02-18 19:48:21","TRT02SDTM":"2021-02-18 19:48:21","TRT02EDTM":"2022-02-19 01:48:21","AP01SDTM":"2020-03-01 23:06:08","AP01EDTM":"2021-02-18 19:48:21","AP02SDTM":"2021-02-18 19:48:21","AP02EDTM":"2022-02-19 01:48:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":720,"DCSREAS":"DEATH","DTHDT":"2022-02-21","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":2,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-21","DTHADY":721,"ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3979,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.72664,"AVALU":"g/L","BASE2":2.72664,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-04-04 23:06:08","ADY":34,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-92","SUBJID":"id-92","SITEID":"CHN-17","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.8508,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-01 23:06:08","TRTEDTM":"2022-02-19 01:48:21","TRT01SDTM":"2020-03-01 23:06:08","TRT01EDTM":"2021-02-18 19:48:21","TRT02SDTM":"2021-02-18 19:48:21","TRT02EDTM":"2022-02-19 01:48:21","AP01SDTM":"2020-03-01 23:06:08","AP01EDTM":"2021-02-18 19:48:21","AP02SDTM":"2021-02-18 19:48:21","AP02EDTM":"2022-02-19 01:48:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":720,"DCSREAS":"DEATH","DTHDT":"2022-02-21","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":2,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-21","DTHADY":721,"ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6780,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02701,"AVALU":"g/L","BASE2":2.72664,"BASE":3.02701,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.30038,"PCHG2":11.01637,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-05-03 23:06:08","ADY":63,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-92","SUBJID":"id-92","SITEID":"CHN-17","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.8508,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-01 23:06:08","TRTEDTM":"2022-02-19 01:48:21","TRT01SDTM":"2020-03-01 23:06:08","TRT01EDTM":"2021-02-18 19:48:21","TRT02SDTM":"2021-02-18 19:48:21","TRT02EDTM":"2022-02-19 01:48:21","AP01SDTM":"2020-03-01 23:06:08","AP01EDTM":"2021-02-18 19:48:21","AP02SDTM":"2021-02-18 19:48:21","AP02EDTM":"2022-02-19 01:48:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":720,"DCSREAS":"DEATH","DTHDT":"2022-02-21","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":2,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-21","DTHADY":721,"ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6100,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77105,"AVALU":"g/L","BASE2":2.72664,"BASE":3.02701,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04442,"PCHG2":1.62904,"CHG":-0.25596,"PCHG":-8.4558,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-07-30 23:06:08","ADY":151,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-92","SUBJID":"id-92","SITEID":"CHN-17","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.8508,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-01 23:06:08","TRTEDTM":"2022-02-19 01:48:21","TRT01SDTM":"2020-03-01 23:06:08","TRT01EDTM":"2021-02-18 19:48:21","TRT02SDTM":"2021-02-18 19:48:21","TRT02EDTM":"2022-02-19 01:48:21","AP01SDTM":"2020-03-01 23:06:08","AP01EDTM":"2021-02-18 19:48:21","AP02SDTM":"2021-02-18 19:48:21","AP02EDTM":"2022-02-19 01:48:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":720,"DCSREAS":"DEATH","DTHDT":"2022-02-21","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":2,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-21","DTHADY":721,"ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2680,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84072,"AVALU":"g/L","BASE2":2.72664,"BASE":3.02701,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11408,"PCHG2":4.18405,"CHG":-0.18629,"PCHG":-6.15433,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-08-15 23:06:08","ADY":167,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-92","SUBJID":"id-92","SITEID":"CHN-17","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.8508,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-01 23:06:08","TRTEDTM":"2022-02-19 01:48:21","TRT01SDTM":"2020-03-01 23:06:08","TRT01EDTM":"2021-02-18 19:48:21","TRT02SDTM":"2021-02-18 19:48:21","TRT02EDTM":"2022-02-19 01:48:21","AP01SDTM":"2020-03-01 23:06:08","AP01EDTM":"2021-02-18 19:48:21","AP02SDTM":"2021-02-18 19:48:21","AP02EDTM":"2022-02-19 01:48:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":720,"DCSREAS":"DEATH","DTHDT":"2022-02-21","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":2,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-21","DTHADY":721,"ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":920,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96059,"AVALU":"g/L","BASE2":2.72664,"BASE":3.02701,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.23396,"PCHG2":8.58044,"CHG":-0.06642,"PCHG":-2.1942,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-09-30 23:06:08","ADY":213,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-92","SUBJID":"id-92","SITEID":"CHN-17","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.8508,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-01 23:06:08","TRTEDTM":"2022-02-19 01:48:21","TRT01SDTM":"2020-03-01 23:06:08","TRT01EDTM":"2021-02-18 19:48:21","TRT02SDTM":"2021-02-18 19:48:21","TRT02EDTM":"2022-02-19 01:48:21","AP01SDTM":"2020-03-01 23:06:08","AP01EDTM":"2021-02-18 19:48:21","AP02SDTM":"2021-02-18 19:48:21","AP02EDTM":"2022-02-19 01:48:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":720,"DCSREAS":"DEATH","DTHDT":"2022-02-21","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":2,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-21","DTHADY":721,"ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7038,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88209,"AVALU":"g/L","BASE2":2.72664,"BASE":3.02701,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15546,"PCHG2":5.70147,"CHG":-0.14492,"PCHG":-4.78749,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-04-25 23:06:08","ADY":420,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-17-id-92","SUBJID":"id-92","SITEID":"CHN-17","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-17","INVNAM":"Dr. CHN-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.8508,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-01 23:06:08","TRTEDTM":"2022-02-19 01:48:21","TRT01SDTM":"2020-03-01 23:06:08","TRT01EDTM":"2021-02-18 19:48:21","TRT02SDTM":"2021-02-18 19:48:21","TRT02EDTM":"2022-02-19 01:48:21","AP01SDTM":"2020-03-01 23:06:08","AP01EDTM":"2021-02-18 19:48:21","AP02SDTM":"2021-02-18 19:48:21","AP02EDTM":"2022-02-19 01:48:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":720,"DCSREAS":"DEATH","DTHDT":"2022-02-21","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":2,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-21","DTHADY":721,"ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7508,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97782,"AVALU":"g/L","BASE2":2.72664,"BASE":3.02701,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.25118,"PCHG2":9.21224,"CHG":-0.04919,"PCHG":-1.6251,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-07-27 23:06:08","ADY":513,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-106","SUBJID":"id-106","SITEID":"CHN-18","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.04956,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-08","TRTSDTM":"2020-12-11 02:07:06","TRTEDTM":"2022-02-15 21:00:47","TRT01SDTM":"2020-12-11 02:07:06","TRT01EDTM":"2021-02-15 15:00:47","TRT02SDTM":"2021-02-15 15:00:47","TRT02EDTM":"2022-02-15 21:00:47","AP01SDTM":"2020-12-11 02:07:06","AP01EDTM":"2021-02-15 15:00:47","AP02SDTM":"2021-02-15 15:00:47","AP02EDTM":"2022-02-15 21:00:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":432,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4919,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.30682,"AVALU":"U/L","BASE2":16.30682,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-23 02:07:06","ADY":194,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-106","SUBJID":"id-106","SITEID":"CHN-18","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.04956,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-08","TRTSDTM":"2020-12-11 02:07:06","TRTEDTM":"2022-02-15 21:00:47","TRT01SDTM":"2020-12-11 02:07:06","TRT01EDTM":"2021-02-15 15:00:47","TRT02SDTM":"2021-02-15 15:00:47","TRT02EDTM":"2022-02-15 21:00:47","AP01SDTM":"2020-12-11 02:07:06","AP01EDTM":"2021-02-15 15:00:47","AP02SDTM":"2021-02-15 15:00:47","AP02EDTM":"2022-02-15 21:00:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":432,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5448,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.24449,"AVALU":"U/L","BASE2":16.30682,"BASE":10.24449,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-6.06233,"PCHG2":-37.17664,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-27 02:07:06","ADY":228,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-106","SUBJID":"id-106","SITEID":"CHN-18","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.04956,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-08","TRTSDTM":"2020-12-11 02:07:06","TRTEDTM":"2022-02-15 21:00:47","TRT01SDTM":"2020-12-11 02:07:06","TRT01EDTM":"2021-02-15 15:00:47","TRT02SDTM":"2021-02-15 15:00:47","TRT02EDTM":"2022-02-15 21:00:47","AP01SDTM":"2020-12-11 02:07:06","AP01EDTM":"2021-02-15 15:00:47","AP02SDTM":"2021-02-15 15:00:47","AP02EDTM":"2022-02-15 21:00:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":432,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5826,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.85831,"AVALU":"U/L","BASE2":16.30682,"BASE":10.24449,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.55149,"PCHG2":89.23564,"CHG":20.61382,"PCHG":201.21857,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-26 02:07:06","ADY":289,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-106","SUBJID":"id-106","SITEID":"CHN-18","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.04956,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-08","TRTSDTM":"2020-12-11 02:07:06","TRTEDTM":"2022-02-15 21:00:47","TRT01SDTM":"2020-12-11 02:07:06","TRT01EDTM":"2021-02-15 15:00:47","TRT02SDTM":"2021-02-15 15:00:47","TRT02EDTM":"2022-02-15 21:00:47","AP01SDTM":"2020-12-11 02:07:06","AP01EDTM":"2021-02-15 15:00:47","AP02SDTM":"2021-02-15 15:00:47","AP02EDTM":"2022-02-15 21:00:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":432,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6841,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.57702,"AVALU":"U/L","BASE2":16.30682,"BASE":10.24449,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.2702,"PCHG2":75.24586,"CHG":18.33253,"PCHG":178.95013,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-02 02:07:06","ADY":295,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-106","SUBJID":"id-106","SITEID":"CHN-18","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.04956,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-08","TRTSDTM":"2020-12-11 02:07:06","TRTEDTM":"2022-02-15 21:00:47","TRT01SDTM":"2020-12-11 02:07:06","TRT01EDTM":"2021-02-15 15:00:47","TRT02SDTM":"2021-02-15 15:00:47","TRT02EDTM":"2022-02-15 21:00:47","AP01SDTM":"2020-12-11 02:07:06","AP01EDTM":"2021-02-15 15:00:47","AP02SDTM":"2021-02-15 15:00:47","AP02EDTM":"2022-02-15 21:00:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":432,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2153,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.15685,"AVALU":"U/L","BASE2":16.30682,"BASE":10.24449,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.85003,"PCHG2":66.53679,"CHG":16.91236,"PCHG":165.08735,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-07 02:07:06","ADY":300,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-106","SUBJID":"id-106","SITEID":"CHN-18","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.04956,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-08","TRTSDTM":"2020-12-11 02:07:06","TRTEDTM":"2022-02-15 21:00:47","TRT01SDTM":"2020-12-11 02:07:06","TRT01EDTM":"2021-02-15 15:00:47","TRT02SDTM":"2021-02-15 15:00:47","TRT02EDTM":"2022-02-15 21:00:47","AP01SDTM":"2020-12-11 02:07:06","AP01EDTM":"2021-02-15 15:00:47","AP02SDTM":"2021-02-15 15:00:47","AP02EDTM":"2022-02-15 21:00:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":432,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8349,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.11256,"AVALU":"U/L","BASE2":16.30682,"BASE":10.24449,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.80574,"PCHG2":35.60316,"CHG":11.86807,"PCHG":115.84829,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-13 02:07:06","ADY":306,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-106","SUBJID":"id-106","SITEID":"CHN-18","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.04956,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-08","TRTSDTM":"2020-12-11 02:07:06","TRTEDTM":"2022-02-15 21:00:47","TRT01SDTM":"2020-12-11 02:07:06","TRT01EDTM":"2021-02-15 15:00:47","TRT02SDTM":"2021-02-15 15:00:47","TRT02EDTM":"2022-02-15 21:00:47","AP01SDTM":"2020-12-11 02:07:06","AP01EDTM":"2021-02-15 15:00:47","AP02SDTM":"2021-02-15 15:00:47","AP02EDTM":"2022-02-15 21:00:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":432,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1401,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":35.09126,"AVALU":"U/L","BASE2":16.30682,"BASE":10.24449,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.78444,"PCHG2":115.1938,"CHG":24.84677,"PCHG":242.53785,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-01 02:07:06","ADY":325,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-106","SUBJID":"id-106","SITEID":"CHN-18","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.04956,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-08","TRTSDTM":"2020-12-11 02:07:06","TRTEDTM":"2022-02-15 21:00:47","TRT01SDTM":"2020-12-11 02:07:06","TRT01EDTM":"2021-02-15 15:00:47","TRT02SDTM":"2021-02-15 15:00:47","TRT02EDTM":"2022-02-15 21:00:47","AP01SDTM":"2020-12-11 02:07:06","AP01EDTM":"2021-02-15 15:00:47","AP02SDTM":"2021-02-15 15:00:47","AP02EDTM":"2022-02-15 21:00:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":432,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6597,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.87108,"AVALU":"mg/L","BASE2":7.87108,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-06-23 02:07:06","ADY":194,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-106","SUBJID":"id-106","SITEID":"CHN-18","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.04956,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-08","TRTSDTM":"2020-12-11 02:07:06","TRTEDTM":"2022-02-15 21:00:47","TRT01SDTM":"2020-12-11 02:07:06","TRT01EDTM":"2021-02-15 15:00:47","TRT02SDTM":"2021-02-15 15:00:47","TRT02EDTM":"2022-02-15 21:00:47","AP01SDTM":"2020-12-11 02:07:06","AP01EDTM":"2021-02-15 15:00:47","AP02SDTM":"2021-02-15 15:00:47","AP02EDTM":"2022-02-15 21:00:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":432,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2682,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.90089,"AVALU":"mg/L","BASE2":7.87108,"BASE":8.90089,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.02981,"PCHG2":13.08344,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-27 02:07:06","ADY":228,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-106","SUBJID":"id-106","SITEID":"CHN-18","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.04956,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-08","TRTSDTM":"2020-12-11 02:07:06","TRTEDTM":"2022-02-15 21:00:47","TRT01SDTM":"2020-12-11 02:07:06","TRT01EDTM":"2021-02-15 15:00:47","TRT02SDTM":"2021-02-15 15:00:47","TRT02EDTM":"2022-02-15 21:00:47","AP01SDTM":"2020-12-11 02:07:06","AP01EDTM":"2021-02-15 15:00:47","AP02SDTM":"2021-02-15 15:00:47","AP02EDTM":"2022-02-15 21:00:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":432,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3322,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.02378,"AVALU":"mg/L","BASE2":7.87108,"BASE":8.90089,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1527,"PCHG2":1.93998,"CHG":-0.87711,"PCHG":-9.85419,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-26 02:07:06","ADY":289,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-106","SUBJID":"id-106","SITEID":"CHN-18","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.04956,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-08","TRTSDTM":"2020-12-11 02:07:06","TRTEDTM":"2022-02-15 21:00:47","TRT01SDTM":"2020-12-11 02:07:06","TRT01EDTM":"2021-02-15 15:00:47","TRT02SDTM":"2021-02-15 15:00:47","TRT02EDTM":"2022-02-15 21:00:47","AP01SDTM":"2020-12-11 02:07:06","AP01EDTM":"2021-02-15 15:00:47","AP02SDTM":"2021-02-15 15:00:47","AP02EDTM":"2022-02-15 21:00:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":432,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":555,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.17668,"AVALU":"mg/L","BASE2":7.87108,"BASE":8.90089,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.30559,"PCHG2":16.58723,"CHG":0.27579,"PCHG":3.09841,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-02 02:07:06","ADY":295,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-106","SUBJID":"id-106","SITEID":"CHN-18","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.04956,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-08","TRTSDTM":"2020-12-11 02:07:06","TRTEDTM":"2022-02-15 21:00:47","TRT01SDTM":"2020-12-11 02:07:06","TRT01EDTM":"2021-02-15 15:00:47","TRT02SDTM":"2021-02-15 15:00:47","TRT02EDTM":"2022-02-15 21:00:47","AP01SDTM":"2020-12-11 02:07:06","AP01EDTM":"2021-02-15 15:00:47","AP02SDTM":"2021-02-15 15:00:47","AP02EDTM":"2022-02-15 21:00:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":432,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6018,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.44778,"AVALU":"mg/L","BASE2":7.87108,"BASE":8.90089,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.5767,"PCHG2":7.32676,"CHG":-0.45311,"PCHG":-5.09065,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-07 02:07:06","ADY":300,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-106","SUBJID":"id-106","SITEID":"CHN-18","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.04956,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-08","TRTSDTM":"2020-12-11 02:07:06","TRTEDTM":"2022-02-15 21:00:47","TRT01SDTM":"2020-12-11 02:07:06","TRT01EDTM":"2021-02-15 15:00:47","TRT02SDTM":"2021-02-15 15:00:47","TRT02EDTM":"2022-02-15 21:00:47","AP01SDTM":"2020-12-11 02:07:06","AP01EDTM":"2021-02-15 15:00:47","AP02SDTM":"2021-02-15 15:00:47","AP02EDTM":"2022-02-15 21:00:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":432,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3211,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.566,"AVALU":"mg/L","BASE2":7.87108,"BASE":8.90089,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.69491,"PCHG2":21.53345,"CHG":0.66511,"PCHG":7.47236,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-13 02:07:06","ADY":306,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-106","SUBJID":"id-106","SITEID":"CHN-18","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.04956,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-08","TRTSDTM":"2020-12-11 02:07:06","TRTEDTM":"2022-02-15 21:00:47","TRT01SDTM":"2020-12-11 02:07:06","TRT01EDTM":"2021-02-15 15:00:47","TRT02SDTM":"2021-02-15 15:00:47","TRT02EDTM":"2022-02-15 21:00:47","AP01SDTM":"2020-12-11 02:07:06","AP01EDTM":"2021-02-15 15:00:47","AP02SDTM":"2021-02-15 15:00:47","AP02EDTM":"2022-02-15 21:00:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":432,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7531,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.11104,"AVALU":"mg/L","BASE2":7.87108,"BASE":8.90089,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.23995,"PCHG2":15.75329,"CHG":0.21015,"PCHG":2.36096,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-01 02:07:06","ADY":325,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-106","SUBJID":"id-106","SITEID":"CHN-18","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.04956,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-08","TRTSDTM":"2020-12-11 02:07:06","TRTEDTM":"2022-02-15 21:00:47","TRT01SDTM":"2020-12-11 02:07:06","TRT01EDTM":"2021-02-15 15:00:47","TRT02SDTM":"2021-02-15 15:00:47","TRT02EDTM":"2022-02-15 21:00:47","AP01SDTM":"2020-12-11 02:07:06","AP01EDTM":"2021-02-15 15:00:47","AP02SDTM":"2021-02-15 15:00:47","AP02EDTM":"2022-02-15 21:00:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":432,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5442,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0148,"AVALU":"g/L","BASE2":3.0148,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"3","ADTM":"2021-06-23 02:07:06","ADY":194,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-106","SUBJID":"id-106","SITEID":"CHN-18","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.04956,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-08","TRTSDTM":"2020-12-11 02:07:06","TRTEDTM":"2022-02-15 21:00:47","TRT01SDTM":"2020-12-11 02:07:06","TRT01EDTM":"2021-02-15 15:00:47","TRT02SDTM":"2021-02-15 15:00:47","TRT02EDTM":"2022-02-15 21:00:47","AP01SDTM":"2020-12-11 02:07:06","AP01EDTM":"2021-02-15 15:00:47","AP02SDTM":"2021-02-15 15:00:47","AP02EDTM":"2022-02-15 21:00:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":432,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3209,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.07126,"AVALU":"g/L","BASE2":3.0148,"BASE":3.07126,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.05646,"PCHG2":1.87269,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2021-07-27 02:07:06","ADY":228,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-106","SUBJID":"id-106","SITEID":"CHN-18","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.04956,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-08","TRTSDTM":"2020-12-11 02:07:06","TRTEDTM":"2022-02-15 21:00:47","TRT01SDTM":"2020-12-11 02:07:06","TRT01EDTM":"2021-02-15 15:00:47","TRT02SDTM":"2021-02-15 15:00:47","TRT02EDTM":"2022-02-15 21:00:47","AP01SDTM":"2020-12-11 02:07:06","AP01EDTM":"2021-02-15 15:00:47","AP02SDTM":"2021-02-15 15:00:47","AP02EDTM":"2022-02-15 21:00:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":432,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7205,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92869,"AVALU":"g/L","BASE2":3.0148,"BASE":3.07126,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08611,"PCHG2":-2.85626,"CHG":-0.14257,"PCHG":-4.64202,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-09-26 02:07:06","ADY":289,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-106","SUBJID":"id-106","SITEID":"CHN-18","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.04956,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-08","TRTSDTM":"2020-12-11 02:07:06","TRTEDTM":"2022-02-15 21:00:47","TRT01SDTM":"2020-12-11 02:07:06","TRT01EDTM":"2021-02-15 15:00:47","TRT02SDTM":"2021-02-15 15:00:47","TRT02EDTM":"2022-02-15 21:00:47","AP01SDTM":"2020-12-11 02:07:06","AP01EDTM":"2021-02-15 15:00:47","AP02SDTM":"2021-02-15 15:00:47","AP02EDTM":"2022-02-15 21:00:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":432,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6571,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04266,"AVALU":"g/L","BASE2":3.0148,"BASE":3.07126,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02786,"PCHG2":0.92403,"CHG":-0.0286,"PCHG":-0.93122,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"3","BTOXGR":"3","ADTM":"2021-10-02 02:07:06","ADY":295,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-106","SUBJID":"id-106","SITEID":"CHN-18","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.04956,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-08","TRTSDTM":"2020-12-11 02:07:06","TRTEDTM":"2022-02-15 21:00:47","TRT01SDTM":"2020-12-11 02:07:06","TRT01EDTM":"2021-02-15 15:00:47","TRT02SDTM":"2021-02-15 15:00:47","TRT02EDTM":"2022-02-15 21:00:47","AP01SDTM":"2020-12-11 02:07:06","AP01EDTM":"2021-02-15 15:00:47","AP02SDTM":"2021-02-15 15:00:47","AP02EDTM":"2022-02-15 21:00:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":432,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6471,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82263,"AVALU":"g/L","BASE2":3.0148,"BASE":3.07126,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19217,"PCHG2":-6.37417,"CHG":-0.24863,"PCHG":-8.09526,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-10-07 02:07:06","ADY":300,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-106","SUBJID":"id-106","SITEID":"CHN-18","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.04956,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-08","TRTSDTM":"2020-12-11 02:07:06","TRTEDTM":"2022-02-15 21:00:47","TRT01SDTM":"2020-12-11 02:07:06","TRT01EDTM":"2021-02-15 15:00:47","TRT02SDTM":"2021-02-15 15:00:47","TRT02EDTM":"2022-02-15 21:00:47","AP01SDTM":"2020-12-11 02:07:06","AP01EDTM":"2021-02-15 15:00:47","AP02SDTM":"2021-02-15 15:00:47","AP02EDTM":"2022-02-15 21:00:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":432,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4538,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81656,"AVALU":"g/L","BASE2":3.0148,"BASE":3.07126,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19824,"PCHG2":-6.57553,"CHG":-0.2547,"PCHG":-8.29291,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-10-13 02:07:06","ADY":306,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-106","SUBJID":"id-106","SITEID":"CHN-18","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.04956,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-08","TRTSDTM":"2020-12-11 02:07:06","TRTEDTM":"2022-02-15 21:00:47","TRT01SDTM":"2020-12-11 02:07:06","TRT01EDTM":"2021-02-15 15:00:47","TRT02SDTM":"2021-02-15 15:00:47","TRT02EDTM":"2022-02-15 21:00:47","AP01SDTM":"2020-12-11 02:07:06","AP01EDTM":"2021-02-15 15:00:47","AP02SDTM":"2021-02-15 15:00:47","AP02EDTM":"2022-02-15 21:00:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":432,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-12","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4497,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.70899,"AVALU":"g/L","BASE2":3.0148,"BASE":3.07126,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.30581,"PCHG2":-10.14357,"CHG":-0.36227,"PCHG":-11.79537,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-11-01 02:07:06","ADY":325,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-170","SUBJID":"id-170","SITEID":"CHN-18","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":12.94197,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-20 08:35:44","TRT01SDTM":"2020-01-20 08:35:44","AP01SDTM":"2020-01-20 08:35:44","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7059,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.33918,"AVALU":"U/L","BASE2":10.33918,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-27 08:35:44","ADY":38,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-170","SUBJID":"id-170","SITEID":"CHN-18","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":12.94197,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-20 08:35:44","TRT01SDTM":"2020-01-20 08:35:44","AP01SDTM":"2020-01-20 08:35:44","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1918,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.01664,"AVALU":"U/L","BASE2":10.33918,"BASE":9.01664,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.32254,"PCHG2":-12.79154,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-16 08:35:44","ADY":56,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-170","SUBJID":"id-170","SITEID":"CHN-18","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":12.94197,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-20 08:35:44","TRT01SDTM":"2020-01-20 08:35:44","AP01SDTM":"2020-01-20 08:35:44","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5042,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.24595,"AVALU":"U/L","BASE2":10.33918,"BASE":9.01664,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.90677,"PCHG2":66.8019,"CHG":8.22931,"PCHG":91.26803,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-30 08:35:44","ADY":70,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-170","SUBJID":"id-170","SITEID":"CHN-18","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":12.94197,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-20 08:35:44","TRT01SDTM":"2020-01-20 08:35:44","AP01SDTM":"2020-01-20 08:35:44","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2214,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.56782,"AVALU":"U/L","BASE2":10.33918,"BASE":9.01664,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.22864,"PCHG2":89.25893,"CHG":10.55118,"PCHG":117.01901,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-09 08:35:44","ADY":141,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-170","SUBJID":"id-170","SITEID":"CHN-18","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":12.94197,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-20 08:35:44","TRT01SDTM":"2020-01-20 08:35:44","AP01SDTM":"2020-01-20 08:35:44","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1740,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.66337,"AVALU":"U/L","BASE2":10.33918,"BASE":9.01664,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.32419,"PCHG2":70.83922,"CHG":8.64673,"PCHG":95.89753,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-30 08:35:44","ADY":162,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-170","SUBJID":"id-170","SITEID":"CHN-18","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":12.94197,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-20 08:35:44","TRT01SDTM":"2020-01-20 08:35:44","AP01SDTM":"2020-01-20 08:35:44","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3420,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.3626,"AVALU":"U/L","BASE2":10.33918,"BASE":9.01664,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.02342,"PCHG2":87.27408,"CHG":10.34596,"PCHG":114.74303,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-28 08:35:44","ADY":464,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-170","SUBJID":"id-170","SITEID":"CHN-18","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":12.94197,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-20 08:35:44","TRT01SDTM":"2020-01-20 08:35:44","AP01SDTM":"2020-01-20 08:35:44","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":822,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.61303,"AVALU":"U/L","BASE2":10.33918,"BASE":9.01664,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":17.27385,"PCHG2":167.07179,"CHG":18.59639,"PCHG":206.24528,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-03 08:35:44","ADY":592,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-170","SUBJID":"id-170","SITEID":"CHN-18","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":12.94197,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-20 08:35:44","TRT01SDTM":"2020-01-20 08:35:44","AP01SDTM":"2020-01-20 08:35:44","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5771,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.85861,"AVALU":"mg/L","BASE2":10.85861,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-02-27 08:35:44","ADY":38,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-170","SUBJID":"id-170","SITEID":"CHN-18","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":12.94197,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-20 08:35:44","TRT01SDTM":"2020-01-20 08:35:44","AP01SDTM":"2020-01-20 08:35:44","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8054,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.60629,"AVALU":"mg/L","BASE2":10.85861,"BASE":9.60629,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.25231,"PCHG2":-11.53289,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-16 08:35:44","ADY":56,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-170","SUBJID":"id-170","SITEID":"CHN-18","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":12.94197,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-20 08:35:44","TRT01SDTM":"2020-01-20 08:35:44","AP01SDTM":"2020-01-20 08:35:44","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3788,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.49729,"AVALU":"mg/L","BASE2":10.85861,"BASE":9.60629,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.36132,"PCHG2":-12.53677,"CHG":-0.10901,"PCHG":-1.13475,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-30 08:35:44","ADY":70,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-170","SUBJID":"id-170","SITEID":"CHN-18","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":12.94197,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-20 08:35:44","TRT01SDTM":"2020-01-20 08:35:44","AP01SDTM":"2020-01-20 08:35:44","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3996,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.34758,"AVALU":"mg/L","BASE2":10.85861,"BASE":9.60629,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.51103,"PCHG2":-32.33404,"CHG":-2.25871,"PCHG":-23.51286,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-06-09 08:35:44","ADY":141,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-170","SUBJID":"id-170","SITEID":"CHN-18","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":12.94197,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-20 08:35:44","TRT01SDTM":"2020-01-20 08:35:44","AP01SDTM":"2020-01-20 08:35:44","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1464,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.24414,"AVALU":"mg/L","BASE2":10.85861,"BASE":9.60629,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.61447,"PCHG2":-24.07736,"CHG":-1.36215,"PCHG":-14.17982,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-30 08:35:44","ADY":162,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-170","SUBJID":"id-170","SITEID":"CHN-18","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":12.94197,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-20 08:35:44","TRT01SDTM":"2020-01-20 08:35:44","AP01SDTM":"2020-01-20 08:35:44","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4724,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":5.8694,"AVALU":"mg/L","BASE2":10.85861,"BASE":9.60629,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.9892,"PCHG2":-45.94699,"CHG":-3.73689,"PCHG":-38.90045,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-04-28 08:35:44","ADY":464,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-170","SUBJID":"id-170","SITEID":"CHN-18","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":12.94197,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-20 08:35:44","TRT01SDTM":"2020-01-20 08:35:44","AP01SDTM":"2020-01-20 08:35:44","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7466,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.21773,"AVALU":"mg/L","BASE2":10.85861,"BASE":9.60629,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.64088,"PCHG2":-24.32061,"CHG":-1.38857,"PCHG":-14.45478,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-03 08:35:44","ADY":592,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-170","SUBJID":"id-170","SITEID":"CHN-18","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":12.94197,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-20 08:35:44","TRT01SDTM":"2020-01-20 08:35:44","AP01SDTM":"2020-01-20 08:35:44","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4366,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88988,"AVALU":"g/L","BASE2":2.88988,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-27 08:35:44","ADY":38,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-170","SUBJID":"id-170","SITEID":"CHN-18","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":12.94197,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-20 08:35:44","TRT01SDTM":"2020-01-20 08:35:44","AP01SDTM":"2020-01-20 08:35:44","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2881,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88068,"AVALU":"g/L","BASE2":2.88988,"BASE":2.88068,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.00921,"PCHG2":-0.31863,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-16 08:35:44","ADY":56,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-170","SUBJID":"id-170","SITEID":"CHN-18","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":12.94197,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-20 08:35:44","TRT01SDTM":"2020-01-20 08:35:44","AP01SDTM":"2020-01-20 08:35:44","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":91,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86132,"AVALU":"g/L","BASE2":2.88988,"BASE":2.88068,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02856,"PCHG2":-0.9884,"CHG":-0.01936,"PCHG":-0.67191,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-30 08:35:44","ADY":70,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-170","SUBJID":"id-170","SITEID":"CHN-18","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":12.94197,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-20 08:35:44","TRT01SDTM":"2020-01-20 08:35:44","AP01SDTM":"2020-01-20 08:35:44","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6069,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.72844,"AVALU":"g/L","BASE2":2.88988,"BASE":2.88068,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16144,"PCHG2":-5.58646,"CHG":-0.15223,"PCHG":-5.28467,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-09 08:35:44","ADY":141,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-170","SUBJID":"id-170","SITEID":"CHN-18","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":12.94197,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-20 08:35:44","TRT01SDTM":"2020-01-20 08:35:44","AP01SDTM":"2020-01-20 08:35:44","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":762,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90833,"AVALU":"g/L","BASE2":2.88988,"BASE":2.88068,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01844,"PCHG2":0.63824,"CHG":0.02765,"PCHG":0.95993,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-30 08:35:44","ADY":162,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-170","SUBJID":"id-170","SITEID":"CHN-18","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":12.94197,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-20 08:35:44","TRT01SDTM":"2020-01-20 08:35:44","AP01SDTM":"2020-01-20 08:35:44","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6433,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00625,"AVALU":"g/L","BASE2":2.88988,"BASE":2.88068,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11637,"PCHG2":4.02674,"CHG":0.12558,"PCHG":4.35926,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-04-28 08:35:44","ADY":464,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-170","SUBJID":"id-170","SITEID":"CHN-18","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":12.94197,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-20 08:35:44","TRT01SDTM":"2020-01-20 08:35:44","AP01SDTM":"2020-01-20 08:35:44","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7532,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95311,"AVALU":"g/L","BASE2":2.88988,"BASE":2.88068,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06323,"PCHG2":2.18784,"CHG":0.07243,"PCHG":2.51449,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-03 08:35:44","ADY":592,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-51","SUBJID":"id-51","SITEID":"CHN-18","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.95289,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:29:04","TRTEDTM":"2022-02-14 22:05:51","TRT01SDTM":"2019-09-25 15:29:04","TRT01EDTM":"2021-02-14 16:05:51","TRT02SDTM":"2021-02-14 16:05:51","TRT02EDTM":"2022-02-14 22:05:51","AP01SDTM":"2019-09-25 15:29:04","AP01EDTM":"2021-02-14 16:05:51","AP02SDTM":"2021-02-14 16:05:51","AP02EDTM":"2022-02-14 22:05:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":874,"DCSREAS":"DEATH","DTHDT":"2022-03-12","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-12","DTHADY":898,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4456,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":35.67287,"AVALU":"U/L","BASE2":35.67287,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-11 15:29:04","ADY":47,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-51","SUBJID":"id-51","SITEID":"CHN-18","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.95289,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:29:04","TRTEDTM":"2022-02-14 22:05:51","TRT01SDTM":"2019-09-25 15:29:04","TRT01EDTM":"2021-02-14 16:05:51","TRT02SDTM":"2021-02-14 16:05:51","TRT02EDTM":"2022-02-14 22:05:51","AP01SDTM":"2019-09-25 15:29:04","AP01EDTM":"2021-02-14 16:05:51","AP02SDTM":"2021-02-14 16:05:51","AP02EDTM":"2022-02-14 22:05:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":874,"DCSREAS":"DEATH","DTHDT":"2022-03-12","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-12","DTHADY":898,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7221,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.25286,"AVALU":"U/L","BASE2":35.67287,"BASE":20.25286,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-15.42001,"PCHG2":-43.22616,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-12 15:29:04","ADY":200,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-51","SUBJID":"id-51","SITEID":"CHN-18","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.95289,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:29:04","TRTEDTM":"2022-02-14 22:05:51","TRT01SDTM":"2019-09-25 15:29:04","TRT01EDTM":"2021-02-14 16:05:51","TRT02SDTM":"2021-02-14 16:05:51","TRT02EDTM":"2022-02-14 22:05:51","AP01SDTM":"2019-09-25 15:29:04","AP01EDTM":"2021-02-14 16:05:51","AP02SDTM":"2021-02-14 16:05:51","AP02EDTM":"2022-02-14 22:05:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":874,"DCSREAS":"DEATH","DTHDT":"2022-03-12","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-12","DTHADY":898,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":941,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.59849,"AVALU":"U/L","BASE2":35.67287,"BASE":20.25286,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.07438,"PCHG2":-17.02801,"CHG":9.34564,"PCHG":46.14478,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-12 15:29:04","ADY":230,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-51","SUBJID":"id-51","SITEID":"CHN-18","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.95289,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:29:04","TRTEDTM":"2022-02-14 22:05:51","TRT01SDTM":"2019-09-25 15:29:04","TRT01EDTM":"2021-02-14 16:05:51","TRT02SDTM":"2021-02-14 16:05:51","TRT02EDTM":"2022-02-14 22:05:51","AP01SDTM":"2019-09-25 15:29:04","AP01EDTM":"2021-02-14 16:05:51","AP02SDTM":"2021-02-14 16:05:51","AP02EDTM":"2022-02-14 22:05:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":874,"DCSREAS":"DEATH","DTHDT":"2022-03-12","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-12","DTHADY":898,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7289,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.38862,"AVALU":"U/L","BASE2":35.67287,"BASE":20.25286,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-30.28425,"PCHG2":-84.89434,"CHG":-14.86423,"PCHG":-73.39327,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-05-20 15:29:04","ADY":238,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-51","SUBJID":"id-51","SITEID":"CHN-18","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.95289,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:29:04","TRTEDTM":"2022-02-14 22:05:51","TRT01SDTM":"2019-09-25 15:29:04","TRT01EDTM":"2021-02-14 16:05:51","TRT02SDTM":"2021-02-14 16:05:51","TRT02EDTM":"2022-02-14 22:05:51","AP01SDTM":"2019-09-25 15:29:04","AP01EDTM":"2021-02-14 16:05:51","AP02SDTM":"2021-02-14 16:05:51","AP02EDTM":"2022-02-14 22:05:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":874,"DCSREAS":"DEATH","DTHDT":"2022-03-12","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-12","DTHADY":898,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2381,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.52834,"AVALU":"U/L","BASE2":35.67287,"BASE":20.25286,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-27.14453,"PCHG2":-76.09292,"CHG":-11.72452,"PCHG":-57.89068,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-24 15:29:04","ADY":456,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-51","SUBJID":"id-51","SITEID":"CHN-18","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.95289,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:29:04","TRTEDTM":"2022-02-14 22:05:51","TRT01SDTM":"2019-09-25 15:29:04","TRT01EDTM":"2021-02-14 16:05:51","TRT02SDTM":"2021-02-14 16:05:51","TRT02EDTM":"2022-02-14 22:05:51","AP01SDTM":"2019-09-25 15:29:04","AP01EDTM":"2021-02-14 16:05:51","AP02SDTM":"2021-02-14 16:05:51","AP02EDTM":"2022-02-14 22:05:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":874,"DCSREAS":"DEATH","DTHDT":"2022-03-12","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-12","DTHADY":898,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8334,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.50827,"AVALU":"U/L","BASE2":35.67287,"BASE":20.25286,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.16461,"PCHG2":-31.29719,"CHG":4.25541,"PCHG":21.01139,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-09 15:29:04","ADY":806,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-51","SUBJID":"id-51","SITEID":"CHN-18","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.95289,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:29:04","TRTEDTM":"2022-02-14 22:05:51","TRT01SDTM":"2019-09-25 15:29:04","TRT01EDTM":"2021-02-14 16:05:51","TRT02SDTM":"2021-02-14 16:05:51","TRT02EDTM":"2022-02-14 22:05:51","AP01SDTM":"2019-09-25 15:29:04","AP01EDTM":"2021-02-14 16:05:51","AP02SDTM":"2021-02-14 16:05:51","AP02EDTM":"2022-02-14 22:05:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":874,"DCSREAS":"DEATH","DTHDT":"2022-03-12","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-12","DTHADY":898,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2738,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.92746,"AVALU":"U/L","BASE2":35.67287,"BASE":20.25286,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.74542,"PCHG2":-41.3351,"CHG":0.6746,"PCHG":3.33088,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-30 15:29:04","ADY":827,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-51","SUBJID":"id-51","SITEID":"CHN-18","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.95289,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:29:04","TRTEDTM":"2022-02-14 22:05:51","TRT01SDTM":"2019-09-25 15:29:04","TRT01EDTM":"2021-02-14 16:05:51","TRT02SDTM":"2021-02-14 16:05:51","TRT02EDTM":"2022-02-14 22:05:51","AP01SDTM":"2019-09-25 15:29:04","AP01EDTM":"2021-02-14 16:05:51","AP02SDTM":"2021-02-14 16:05:51","AP02EDTM":"2022-02-14 22:05:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":874,"DCSREAS":"DEATH","DTHDT":"2022-03-12","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-12","DTHADY":898,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":55,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.32579,"AVALU":"mg/L","BASE2":8.32579,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-11 15:29:04","ADY":47,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-51","SUBJID":"id-51","SITEID":"CHN-18","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.95289,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:29:04","TRTEDTM":"2022-02-14 22:05:51","TRT01SDTM":"2019-09-25 15:29:04","TRT01EDTM":"2021-02-14 16:05:51","TRT02SDTM":"2021-02-14 16:05:51","TRT02EDTM":"2022-02-14 22:05:51","AP01SDTM":"2019-09-25 15:29:04","AP01EDTM":"2021-02-14 16:05:51","AP02SDTM":"2021-02-14 16:05:51","AP02EDTM":"2022-02-14 22:05:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":874,"DCSREAS":"DEATH","DTHDT":"2022-03-12","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-12","DTHADY":898,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5013,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.56986,"AVALU":"mg/L","BASE2":8.32579,"BASE":9.56986,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.24407,"PCHG2":14.94235,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-12 15:29:04","ADY":200,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-51","SUBJID":"id-51","SITEID":"CHN-18","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.95289,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:29:04","TRTEDTM":"2022-02-14 22:05:51","TRT01SDTM":"2019-09-25 15:29:04","TRT01EDTM":"2021-02-14 16:05:51","TRT02SDTM":"2021-02-14 16:05:51","TRT02EDTM":"2022-02-14 22:05:51","AP01SDTM":"2019-09-25 15:29:04","AP01EDTM":"2021-02-14 16:05:51","AP02SDTM":"2021-02-14 16:05:51","AP02EDTM":"2022-02-14 22:05:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":874,"DCSREAS":"DEATH","DTHDT":"2022-03-12","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-12","DTHADY":898,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3208,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.20063,"AVALU":"mg/L","BASE2":8.32579,"BASE":9.56986,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.87484,"PCHG2":22.51846,"CHG":0.63077,"PCHG":6.59122,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-05-12 15:29:04","ADY":230,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-51","SUBJID":"id-51","SITEID":"CHN-18","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.95289,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:29:04","TRTEDTM":"2022-02-14 22:05:51","TRT01SDTM":"2019-09-25 15:29:04","TRT01EDTM":"2021-02-14 16:05:51","TRT02SDTM":"2021-02-14 16:05:51","TRT02EDTM":"2022-02-14 22:05:51","AP01SDTM":"2019-09-25 15:29:04","AP01EDTM":"2021-02-14 16:05:51","AP02SDTM":"2021-02-14 16:05:51","AP02EDTM":"2022-02-14 22:05:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":874,"DCSREAS":"DEATH","DTHDT":"2022-03-12","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-12","DTHADY":898,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1787,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.65959,"AVALU":"mg/L","BASE2":8.32579,"BASE":9.56986,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.6662,"PCHG2":-8.00165,"CHG":-1.91027,"PCHG":-19.96131,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-05-20 15:29:04","ADY":238,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-51","SUBJID":"id-51","SITEID":"CHN-18","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.95289,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:29:04","TRTEDTM":"2022-02-14 22:05:51","TRT01SDTM":"2019-09-25 15:29:04","TRT01EDTM":"2021-02-14 16:05:51","TRT02SDTM":"2021-02-14 16:05:51","TRT02EDTM":"2022-02-14 22:05:51","AP01SDTM":"2019-09-25 15:29:04","AP01EDTM":"2021-02-14 16:05:51","AP02SDTM":"2021-02-14 16:05:51","AP02EDTM":"2022-02-14 22:05:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":874,"DCSREAS":"DEATH","DTHDT":"2022-03-12","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-12","DTHADY":898,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3593,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.0723,"AVALU":"mg/L","BASE2":8.32579,"BASE":9.56986,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.74651,"PCHG2":32.98804,"CHG":1.50245,"PCHG":15.69977,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-12-24 15:29:04","ADY":456,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-51","SUBJID":"id-51","SITEID":"CHN-18","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.95289,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:29:04","TRTEDTM":"2022-02-14 22:05:51","TRT01SDTM":"2019-09-25 15:29:04","TRT01EDTM":"2021-02-14 16:05:51","TRT02SDTM":"2021-02-14 16:05:51","TRT02EDTM":"2022-02-14 22:05:51","AP01SDTM":"2019-09-25 15:29:04","AP01EDTM":"2021-02-14 16:05:51","AP02SDTM":"2021-02-14 16:05:51","AP02EDTM":"2022-02-14 22:05:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":874,"DCSREAS":"DEATH","DTHDT":"2022-03-12","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-12","DTHADY":898,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3773,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.84403,"AVALU":"mg/L","BASE2":8.32579,"BASE":9.56986,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.51824,"PCHG2":18.23541,"CHG":0.27417,"PCHG":2.86496,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-09 15:29:04","ADY":806,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-51","SUBJID":"id-51","SITEID":"CHN-18","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.95289,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:29:04","TRTEDTM":"2022-02-14 22:05:51","TRT01SDTM":"2019-09-25 15:29:04","TRT01EDTM":"2021-02-14 16:05:51","TRT02SDTM":"2021-02-14 16:05:51","TRT02EDTM":"2022-02-14 22:05:51","AP01SDTM":"2019-09-25 15:29:04","AP01EDTM":"2021-02-14 16:05:51","AP02SDTM":"2021-02-14 16:05:51","AP02EDTM":"2022-02-14 22:05:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":874,"DCSREAS":"DEATH","DTHDT":"2022-03-12","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-12","DTHADY":898,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7849,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.84464,"AVALU":"mg/L","BASE2":8.32579,"BASE":9.56986,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.51885,"PCHG2":6.23179,"CHG":-0.72522,"PCHG":-7.5782,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-30 15:29:04","ADY":827,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-51","SUBJID":"id-51","SITEID":"CHN-18","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.95289,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:29:04","TRTEDTM":"2022-02-14 22:05:51","TRT01SDTM":"2019-09-25 15:29:04","TRT01EDTM":"2021-02-14 16:05:51","TRT02SDTM":"2021-02-14 16:05:51","TRT02EDTM":"2022-02-14 22:05:51","AP01SDTM":"2019-09-25 15:29:04","AP01EDTM":"2021-02-14 16:05:51","AP02SDTM":"2021-02-14 16:05:51","AP02EDTM":"2022-02-14 22:05:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":874,"DCSREAS":"DEATH","DTHDT":"2022-03-12","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-12","DTHADY":898,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8091,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85806,"AVALU":"g/L","BASE2":2.85806,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-11 15:29:04","ADY":47,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-51","SUBJID":"id-51","SITEID":"CHN-18","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.95289,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:29:04","TRTEDTM":"2022-02-14 22:05:51","TRT01SDTM":"2019-09-25 15:29:04","TRT01EDTM":"2021-02-14 16:05:51","TRT02SDTM":"2021-02-14 16:05:51","TRT02EDTM":"2022-02-14 22:05:51","AP01SDTM":"2019-09-25 15:29:04","AP01EDTM":"2021-02-14 16:05:51","AP02SDTM":"2021-02-14 16:05:51","AP02EDTM":"2022-02-14 22:05:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":874,"DCSREAS":"DEATH","DTHDT":"2022-03-12","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-12","DTHADY":898,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6444,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82836,"AVALU":"g/L","BASE2":2.85806,"BASE":2.82836,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.0297,"PCHG2":-1.0392,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-12 15:29:04","ADY":200,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-51","SUBJID":"id-51","SITEID":"CHN-18","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.95289,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:29:04","TRTEDTM":"2022-02-14 22:05:51","TRT01SDTM":"2019-09-25 15:29:04","TRT01EDTM":"2021-02-14 16:05:51","TRT02SDTM":"2021-02-14 16:05:51","TRT02EDTM":"2022-02-14 22:05:51","AP01SDTM":"2019-09-25 15:29:04","AP01EDTM":"2021-02-14 16:05:51","AP02SDTM":"2021-02-14 16:05:51","AP02EDTM":"2022-02-14 22:05:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":874,"DCSREAS":"DEATH","DTHDT":"2022-03-12","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-12","DTHADY":898,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":635,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03022,"AVALU":"g/L","BASE2":2.85806,"BASE":2.82836,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17216,"PCHG2":6.02372,"CHG":0.20186,"PCHG":7.13709,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-05-12 15:29:04","ADY":230,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-51","SUBJID":"id-51","SITEID":"CHN-18","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.95289,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:29:04","TRTEDTM":"2022-02-14 22:05:51","TRT01SDTM":"2019-09-25 15:29:04","TRT01EDTM":"2021-02-14 16:05:51","TRT02SDTM":"2021-02-14 16:05:51","TRT02EDTM":"2022-02-14 22:05:51","AP01SDTM":"2019-09-25 15:29:04","AP01EDTM":"2021-02-14 16:05:51","AP02SDTM":"2021-02-14 16:05:51","AP02EDTM":"2022-02-14 22:05:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":874,"DCSREAS":"DEATH","DTHDT":"2022-03-12","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-12","DTHADY":898,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3036,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83866,"AVALU":"g/L","BASE2":2.85806,"BASE":2.82836,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0194,"PCHG2":-0.67865,"CHG":0.0103,"PCHG":0.36434,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-20 15:29:04","ADY":238,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-51","SUBJID":"id-51","SITEID":"CHN-18","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.95289,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:29:04","TRTEDTM":"2022-02-14 22:05:51","TRT01SDTM":"2019-09-25 15:29:04","TRT01EDTM":"2021-02-14 16:05:51","TRT02SDTM":"2021-02-14 16:05:51","TRT02EDTM":"2022-02-14 22:05:51","AP01SDTM":"2019-09-25 15:29:04","AP01EDTM":"2021-02-14 16:05:51","AP02SDTM":"2021-02-14 16:05:51","AP02EDTM":"2022-02-14 22:05:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":874,"DCSREAS":"DEATH","DTHDT":"2022-03-12","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-12","DTHADY":898,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3560,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99556,"AVALU":"g/L","BASE2":2.85806,"BASE":2.82836,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1375,"PCHG2":4.81107,"CHG":0.1672,"PCHG":5.9117,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-24 15:29:04","ADY":456,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-51","SUBJID":"id-51","SITEID":"CHN-18","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.95289,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:29:04","TRTEDTM":"2022-02-14 22:05:51","TRT01SDTM":"2019-09-25 15:29:04","TRT01EDTM":"2021-02-14 16:05:51","TRT02SDTM":"2021-02-14 16:05:51","TRT02EDTM":"2022-02-14 22:05:51","AP01SDTM":"2019-09-25 15:29:04","AP01EDTM":"2021-02-14 16:05:51","AP02SDTM":"2021-02-14 16:05:51","AP02EDTM":"2022-02-14 22:05:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":874,"DCSREAS":"DEATH","DTHDT":"2022-03-12","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-12","DTHADY":898,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1998,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95862,"AVALU":"g/L","BASE2":2.85806,"BASE":2.82836,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10056,"PCHG2":3.51832,"CHG":0.13026,"PCHG":4.60538,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-09 15:29:04","ADY":806,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-18-id-51","SUBJID":"id-51","SITEID":"CHN-18","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-18","INVNAM":"Dr. CHN-18 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.95289,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:29:04","TRTEDTM":"2022-02-14 22:05:51","TRT01SDTM":"2019-09-25 15:29:04","TRT01EDTM":"2021-02-14 16:05:51","TRT02SDTM":"2021-02-14 16:05:51","TRT02EDTM":"2022-02-14 22:05:51","AP01SDTM":"2019-09-25 15:29:04","AP01EDTM":"2021-02-14 16:05:51","AP02SDTM":"2021-02-14 16:05:51","AP02EDTM":"2022-02-14 22:05:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":874,"DCSREAS":"DEATH","DTHDT":"2022-03-12","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":26,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-12","DTHADY":898,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5052,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82478,"AVALU":"g/L","BASE2":2.85806,"BASE":2.82836,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03328,"PCHG2":-1.16438,"CHG":-0.00358,"PCHG":-0.1265,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-30 15:29:04","ADY":827,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-118","SUBJID":"id-118","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.22229,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-09 11:48:53","TRTEDTM":"2023-04-10 05:48:53","TRT01SDTM":"2020-04-09 11:48:53","TRT01EDTM":"2022-04-09 23:48:53","TRT02SDTM":"2022-04-09 23:48:53","TRT02EDTM":"2023-04-10 05:48:53","AP01SDTM":"2020-04-09 11:48:53","AP01EDTM":"2022-04-09 23:48:53","AP02SDTM":"2022-04-09 23:48:53","AP02EDTM":"2023-04-10 05:48:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-10","EOSDY":1096,"LSTALVDT":"2023-04-20","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6374,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.96777,"AVALU":"U/L","BASE2":28.96777,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-07 11:48:53","ADY":89,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-118","SUBJID":"id-118","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.22229,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-09 11:48:53","TRTEDTM":"2023-04-10 05:48:53","TRT01SDTM":"2020-04-09 11:48:53","TRT01EDTM":"2022-04-09 23:48:53","TRT02SDTM":"2022-04-09 23:48:53","TRT02EDTM":"2023-04-10 05:48:53","AP01SDTM":"2020-04-09 11:48:53","AP01EDTM":"2022-04-09 23:48:53","AP02SDTM":"2022-04-09 23:48:53","AP02EDTM":"2023-04-10 05:48:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-10","EOSDY":1096,"LSTALVDT":"2023-04-20","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2757,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.76295,"AVALU":"U/L","BASE2":28.96777,"BASE":31.76295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.79518,"PCHG2":9.64928,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-23 11:48:53","ADY":136,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-118","SUBJID":"id-118","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.22229,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-09 11:48:53","TRTEDTM":"2023-04-10 05:48:53","TRT01SDTM":"2020-04-09 11:48:53","TRT01EDTM":"2022-04-09 23:48:53","TRT02SDTM":"2022-04-09 23:48:53","TRT02EDTM":"2023-04-10 05:48:53","AP01SDTM":"2020-04-09 11:48:53","AP01EDTM":"2022-04-09 23:48:53","AP02SDTM":"2022-04-09 23:48:53","AP02EDTM":"2023-04-10 05:48:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-10","EOSDY":1096,"LSTALVDT":"2023-04-20","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2641,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.06719,"AVALU":"U/L","BASE2":28.96777,"BASE":31.76295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.90058,"PCHG2":-58.34269,"CHG":-19.69576,"PCHG":-62.00859,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-29 11:48:53","ADY":264,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-118","SUBJID":"id-118","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.22229,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-09 11:48:53","TRTEDTM":"2023-04-10 05:48:53","TRT01SDTM":"2020-04-09 11:48:53","TRT01EDTM":"2022-04-09 23:48:53","TRT02SDTM":"2022-04-09 23:48:53","TRT02EDTM":"2023-04-10 05:48:53","AP01SDTM":"2020-04-09 11:48:53","AP01EDTM":"2022-04-09 23:48:53","AP02SDTM":"2022-04-09 23:48:53","AP02EDTM":"2023-04-10 05:48:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-10","EOSDY":1096,"LSTALVDT":"2023-04-20","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7771,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.94667,"AVALU":"U/L","BASE2":28.96777,"BASE":31.76295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.0211,"PCHG2":-48.40241,"CHG":-16.81628,"PCHG":-52.94306,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-20 11:48:53","ADY":376,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-118","SUBJID":"id-118","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.22229,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-09 11:48:53","TRTEDTM":"2023-04-10 05:48:53","TRT01SDTM":"2020-04-09 11:48:53","TRT01EDTM":"2022-04-09 23:48:53","TRT02SDTM":"2022-04-09 23:48:53","TRT02EDTM":"2023-04-10 05:48:53","AP01SDTM":"2020-04-09 11:48:53","AP01EDTM":"2022-04-09 23:48:53","AP02SDTM":"2022-04-09 23:48:53","AP02EDTM":"2023-04-10 05:48:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-10","EOSDY":1096,"LSTALVDT":"2023-04-20","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3057,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.76095,"AVALU":"U/L","BASE2":28.96777,"BASE":31.76295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-26.20682,"PCHG2":-90.4689,"CHG":-29.002,"PCHG":-91.30765,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-10-30 11:48:53","ADY":934,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-118","SUBJID":"id-118","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.22229,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-09 11:48:53","TRTEDTM":"2023-04-10 05:48:53","TRT01SDTM":"2020-04-09 11:48:53","TRT01EDTM":"2022-04-09 23:48:53","TRT02SDTM":"2022-04-09 23:48:53","TRT02EDTM":"2023-04-10 05:48:53","AP01SDTM":"2020-04-09 11:48:53","AP01EDTM":"2022-04-09 23:48:53","AP02SDTM":"2022-04-09 23:48:53","AP02EDTM":"2023-04-10 05:48:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-10","EOSDY":1096,"LSTALVDT":"2023-04-20","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":506,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.66551,"AVALU":"U/L","BASE2":28.96777,"BASE":31.76295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.30226,"PCHG2":-18.30399,"CHG":-8.09744,"PCHG":-25.49334,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-09 11:48:53","ADY":944,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-118","SUBJID":"id-118","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.22229,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-09 11:48:53","TRTEDTM":"2023-04-10 05:48:53","TRT01SDTM":"2020-04-09 11:48:53","TRT01EDTM":"2022-04-09 23:48:53","TRT02SDTM":"2022-04-09 23:48:53","TRT02EDTM":"2023-04-10 05:48:53","AP01SDTM":"2020-04-09 11:48:53","AP01EDTM":"2022-04-09 23:48:53","AP02SDTM":"2022-04-09 23:48:53","AP02EDTM":"2023-04-10 05:48:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-10","EOSDY":1096,"LSTALVDT":"2023-04-20","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4581,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.20226,"AVALU":"U/L","BASE2":28.96777,"BASE":31.76295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-22.76551,"PCHG2":-78.58909,"CHG":-25.56069,"PCHG":-80.47328,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-12-16 11:48:53","ADY":981,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-118","SUBJID":"id-118","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.22229,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-09 11:48:53","TRTEDTM":"2023-04-10 05:48:53","TRT01SDTM":"2020-04-09 11:48:53","TRT01EDTM":"2022-04-09 23:48:53","TRT02SDTM":"2022-04-09 23:48:53","TRT02EDTM":"2023-04-10 05:48:53","AP01SDTM":"2020-04-09 11:48:53","AP01EDTM":"2022-04-09 23:48:53","AP02SDTM":"2022-04-09 23:48:53","AP02EDTM":"2023-04-10 05:48:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-10","EOSDY":1096,"LSTALVDT":"2023-04-20","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8009,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.02295,"AVALU":"mg/L","BASE2":10.02295,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-07-07 11:48:53","ADY":89,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-118","SUBJID":"id-118","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.22229,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-09 11:48:53","TRTEDTM":"2023-04-10 05:48:53","TRT01SDTM":"2020-04-09 11:48:53","TRT01EDTM":"2022-04-09 23:48:53","TRT02SDTM":"2022-04-09 23:48:53","TRT02EDTM":"2023-04-10 05:48:53","AP01SDTM":"2020-04-09 11:48:53","AP01EDTM":"2022-04-09 23:48:53","AP02SDTM":"2022-04-09 23:48:53","AP02EDTM":"2023-04-10 05:48:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-10","EOSDY":1096,"LSTALVDT":"2023-04-20","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5676,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.63936,"AVALU":"mg/L","BASE2":10.02295,"BASE":8.63936,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.38359,"PCHG2":-13.80425,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-23 11:48:53","ADY":136,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-118","SUBJID":"id-118","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.22229,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-09 11:48:53","TRTEDTM":"2023-04-10 05:48:53","TRT01SDTM":"2020-04-09 11:48:53","TRT01EDTM":"2022-04-09 23:48:53","TRT02SDTM":"2022-04-09 23:48:53","TRT02EDTM":"2023-04-10 05:48:53","AP01SDTM":"2020-04-09 11:48:53","AP01EDTM":"2022-04-09 23:48:53","AP02SDTM":"2022-04-09 23:48:53","AP02EDTM":"2023-04-10 05:48:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-10","EOSDY":1096,"LSTALVDT":"2023-04-20","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7845,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.82341,"AVALU":"mg/L","BASE2":10.02295,"BASE":8.63936,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.19954,"PCHG2":-11.96796,"CHG":0.18405,"PCHG":2.13036,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-29 11:48:53","ADY":264,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-118","SUBJID":"id-118","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.22229,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-09 11:48:53","TRTEDTM":"2023-04-10 05:48:53","TRT01SDTM":"2020-04-09 11:48:53","TRT01EDTM":"2022-04-09 23:48:53","TRT02SDTM":"2022-04-09 23:48:53","TRT02EDTM":"2023-04-10 05:48:53","AP01SDTM":"2020-04-09 11:48:53","AP01EDTM":"2022-04-09 23:48:53","AP02SDTM":"2022-04-09 23:48:53","AP02EDTM":"2023-04-10 05:48:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-10","EOSDY":1096,"LSTALVDT":"2023-04-20","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5561,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.34905,"AVALU":"mg/L","BASE2":10.02295,"BASE":8.63936,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.67389,"PCHG2":-26.67773,"CHG":-1.2903,"PCHG":-14.93517,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-04-20 11:48:53","ADY":376,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-118","SUBJID":"id-118","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.22229,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-09 11:48:53","TRTEDTM":"2023-04-10 05:48:53","TRT01SDTM":"2020-04-09 11:48:53","TRT01EDTM":"2022-04-09 23:48:53","TRT02SDTM":"2022-04-09 23:48:53","TRT02EDTM":"2023-04-10 05:48:53","AP01SDTM":"2020-04-09 11:48:53","AP01EDTM":"2022-04-09 23:48:53","AP02SDTM":"2022-04-09 23:48:53","AP02EDTM":"2023-04-10 05:48:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-10","EOSDY":1096,"LSTALVDT":"2023-04-20","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1635,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.22036,"AVALU":"mg/L","BASE2":10.02295,"BASE":8.63936,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.19741,"PCHG2":1.96959,"CHG":1.581,"PCHG":18.30001,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2022-10-30 11:48:53","ADY":934,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-118","SUBJID":"id-118","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.22229,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-09 11:48:53","TRTEDTM":"2023-04-10 05:48:53","TRT01SDTM":"2020-04-09 11:48:53","TRT01EDTM":"2022-04-09 23:48:53","TRT02SDTM":"2022-04-09 23:48:53","TRT02EDTM":"2023-04-10 05:48:53","AP01SDTM":"2020-04-09 11:48:53","AP01EDTM":"2022-04-09 23:48:53","AP02SDTM":"2022-04-09 23:48:53","AP02EDTM":"2023-04-10 05:48:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-10","EOSDY":1096,"LSTALVDT":"2023-04-20","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8097,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.36019,"AVALU":"mg/L","BASE2":10.02295,"BASE":8.63936,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.66276,"PCHG2":-16.58951,"CHG":-0.27917,"PCHG":-3.23133,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-09 11:48:53","ADY":944,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-118","SUBJID":"id-118","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.22229,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-09 11:48:53","TRTEDTM":"2023-04-10 05:48:53","TRT01SDTM":"2020-04-09 11:48:53","TRT01EDTM":"2022-04-09 23:48:53","TRT02SDTM":"2022-04-09 23:48:53","TRT02EDTM":"2023-04-10 05:48:53","AP01SDTM":"2020-04-09 11:48:53","AP01EDTM":"2022-04-09 23:48:53","AP02SDTM":"2022-04-09 23:48:53","AP02EDTM":"2023-04-10 05:48:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-10","EOSDY":1096,"LSTALVDT":"2023-04-20","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1384,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.99449,"AVALU":"mg/L","BASE2":10.02295,"BASE":8.63936,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02846,"PCHG2":-0.28392,"CHG":1.35514,"PCHG":15.68561,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-16 11:48:53","ADY":981,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-118","SUBJID":"id-118","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.22229,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-09 11:48:53","TRTEDTM":"2023-04-10 05:48:53","TRT01SDTM":"2020-04-09 11:48:53","TRT01EDTM":"2022-04-09 23:48:53","TRT02SDTM":"2022-04-09 23:48:53","TRT02EDTM":"2023-04-10 05:48:53","AP01SDTM":"2020-04-09 11:48:53","AP01EDTM":"2022-04-09 23:48:53","AP02SDTM":"2022-04-09 23:48:53","AP02EDTM":"2023-04-10 05:48:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-10","EOSDY":1096,"LSTALVDT":"2023-04-20","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6150,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98398,"AVALU":"g/L","BASE2":2.98398,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-07 11:48:53","ADY":89,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-118","SUBJID":"id-118","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.22229,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-09 11:48:53","TRTEDTM":"2023-04-10 05:48:53","TRT01SDTM":"2020-04-09 11:48:53","TRT01EDTM":"2022-04-09 23:48:53","TRT02SDTM":"2022-04-09 23:48:53","TRT02EDTM":"2023-04-10 05:48:53","AP01SDTM":"2020-04-09 11:48:53","AP01EDTM":"2022-04-09 23:48:53","AP02SDTM":"2022-04-09 23:48:53","AP02EDTM":"2023-04-10 05:48:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-10","EOSDY":1096,"LSTALVDT":"2023-04-20","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4123,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86321,"AVALU":"g/L","BASE2":2.98398,"BASE":2.86321,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.12077,"PCHG2":-4.04715,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-23 11:48:53","ADY":136,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-118","SUBJID":"id-118","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.22229,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-09 11:48:53","TRTEDTM":"2023-04-10 05:48:53","TRT01SDTM":"2020-04-09 11:48:53","TRT01EDTM":"2022-04-09 23:48:53","TRT02SDTM":"2022-04-09 23:48:53","TRT02EDTM":"2023-04-10 05:48:53","AP01SDTM":"2020-04-09 11:48:53","AP01EDTM":"2022-04-09 23:48:53","AP02SDTM":"2022-04-09 23:48:53","AP02EDTM":"2023-04-10 05:48:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-10","EOSDY":1096,"LSTALVDT":"2023-04-20","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4054,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74182,"AVALU":"g/L","BASE2":2.98398,"BASE":2.86321,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.24215,"PCHG2":-8.11506,"CHG":-0.12139,"PCHG":-4.23949,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-29 11:48:53","ADY":264,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-118","SUBJID":"id-118","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.22229,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-09 11:48:53","TRTEDTM":"2023-04-10 05:48:53","TRT01SDTM":"2020-04-09 11:48:53","TRT01EDTM":"2022-04-09 23:48:53","TRT02SDTM":"2022-04-09 23:48:53","TRT02EDTM":"2023-04-10 05:48:53","AP01SDTM":"2020-04-09 11:48:53","AP01EDTM":"2022-04-09 23:48:53","AP02SDTM":"2022-04-09 23:48:53","AP02EDTM":"2023-04-10 05:48:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-10","EOSDY":1096,"LSTALVDT":"2023-04-20","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8268,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.07193,"AVALU":"g/L","BASE2":2.98398,"BASE":2.86321,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08796,"PCHG2":2.94763,"CHG":0.20872,"PCHG":7.28981,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-04-20 11:48:53","ADY":376,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-118","SUBJID":"id-118","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.22229,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-09 11:48:53","TRTEDTM":"2023-04-10 05:48:53","TRT01SDTM":"2020-04-09 11:48:53","TRT01EDTM":"2022-04-09 23:48:53","TRT02SDTM":"2022-04-09 23:48:53","TRT02EDTM":"2023-04-10 05:48:53","AP01SDTM":"2020-04-09 11:48:53","AP01EDTM":"2022-04-09 23:48:53","AP02SDTM":"2022-04-09 23:48:53","AP02EDTM":"2023-04-10 05:48:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-10","EOSDY":1096,"LSTALVDT":"2023-04-20","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1566,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78935,"AVALU":"g/L","BASE2":2.98398,"BASE":2.86321,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19462,"PCHG2":-6.52227,"CHG":-0.07386,"PCHG":-2.57951,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-30 11:48:53","ADY":934,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-118","SUBJID":"id-118","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.22229,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-09 11:48:53","TRTEDTM":"2023-04-10 05:48:53","TRT01SDTM":"2020-04-09 11:48:53","TRT01EDTM":"2022-04-09 23:48:53","TRT02SDTM":"2022-04-09 23:48:53","TRT02EDTM":"2023-04-10 05:48:53","AP01SDTM":"2020-04-09 11:48:53","AP01EDTM":"2022-04-09 23:48:53","AP02SDTM":"2022-04-09 23:48:53","AP02EDTM":"2023-04-10 05:48:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-10","EOSDY":1096,"LSTALVDT":"2023-04-20","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3185,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.70294,"AVALU":"g/L","BASE2":2.98398,"BASE":2.86321,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.28103,"PCHG2":-9.41809,"CHG":-0.16027,"PCHG":-5.59747,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-09 11:48:53","ADY":944,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-118","SUBJID":"id-118","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.22229,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-09 11:48:53","TRTEDTM":"2023-04-10 05:48:53","TRT01SDTM":"2020-04-09 11:48:53","TRT01EDTM":"2022-04-09 23:48:53","TRT02SDTM":"2022-04-09 23:48:53","TRT02EDTM":"2023-04-10 05:48:53","AP01SDTM":"2020-04-09 11:48:53","AP01EDTM":"2022-04-09 23:48:53","AP02SDTM":"2022-04-09 23:48:53","AP02EDTM":"2023-04-10 05:48:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-10","EOSDY":1096,"LSTALVDT":"2023-04-20","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7691,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89903,"AVALU":"g/L","BASE2":2.98398,"BASE":2.86321,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08494,"PCHG2":-2.8466,"CHG":0.03582,"PCHG":1.25119,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-16 11:48:53","ADY":981,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-149","SUBJID":"id-149","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.64074,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-03","TRTSDTM":"2020-01-07 08:26:42","TRT01SDTM":"2020-01-07 08:26:42","AP01SDTM":"2020-01-07 08:26:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7269,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":41.07978,"AVALU":"U/L","BASE2":41.07978,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-01 08:26:42","ADY":85,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-149","SUBJID":"id-149","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.64074,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-03","TRTSDTM":"2020-01-07 08:26:42","TRT01SDTM":"2020-01-07 08:26:42","AP01SDTM":"2020-01-07 08:26:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7386,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.52069,"AVALU":"U/L","BASE2":41.07978,"BASE":20.52069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-20.55909,"PCHG2":-50.04674,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-07 08:26:42","ADY":121,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-149","SUBJID":"id-149","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.64074,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-03","TRTSDTM":"2020-01-07 08:26:42","TRT01SDTM":"2020-01-07 08:26:42","AP01SDTM":"2020-01-07 08:26:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2332,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.04234,"AVALU":"U/L","BASE2":41.07978,"BASE":20.52069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-25.03744,"PCHG2":-60.94833,"CHG":-4.47835,"PCHG":-21.82358,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-20 08:26:42","ADY":226,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-149","SUBJID":"id-149","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.64074,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-03","TRTSDTM":"2020-01-07 08:26:42","TRT01SDTM":"2020-01-07 08:26:42","AP01SDTM":"2020-01-07 08:26:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7970,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.46863,"AVALU":"U/L","BASE2":41.07978,"BASE":20.52069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-15.61115,"PCHG2":-38.00203,"CHG":4.94794,"PCHG":24.11195,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-01 08:26:42","ADY":268,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-149","SUBJID":"id-149","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.64074,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-03","TRTSDTM":"2020-01-07 08:26:42","TRT01SDTM":"2020-01-07 08:26:42","AP01SDTM":"2020-01-07 08:26:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7009,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.32006,"AVALU":"U/L","BASE2":41.07978,"BASE":20.52069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.75972,"PCHG2":-31.06084,"CHG":7.79937,"PCHG":38.00732,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-31 08:26:42","ADY":390,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-149","SUBJID":"id-149","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.64074,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-03","TRTSDTM":"2020-01-07 08:26:42","TRT01SDTM":"2020-01-07 08:26:42","AP01SDTM":"2020-01-07 08:26:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8265,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.6333,"AVALU":"U/L","BASE2":41.07978,"BASE":20.52069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-20.44649,"PCHG2":-49.77262,"CHG":0.1126,"PCHG":0.54873,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-07 08:26:42","ADY":578,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-149","SUBJID":"id-149","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.64074,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-03","TRTSDTM":"2020-01-07 08:26:42","TRT01SDTM":"2020-01-07 08:26:42","AP01SDTM":"2020-01-07 08:26:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3385,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.72586,"AVALU":"U/L","BASE2":41.07978,"BASE":20.52069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-35.35393,"PCHG2":-86.06162,"CHG":-14.79484,"PCHG":-72.09715,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-12-10 08:26:42","ADY":703,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-149","SUBJID":"id-149","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.64074,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-03","TRTSDTM":"2020-01-07 08:26:42","TRT01SDTM":"2020-01-07 08:26:42","AP01SDTM":"2020-01-07 08:26:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2091,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.82458,"AVALU":"mg/L","BASE2":8.82458,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-01 08:26:42","ADY":85,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-149","SUBJID":"id-149","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.64074,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-03","TRTSDTM":"2020-01-07 08:26:42","TRT01SDTM":"2020-01-07 08:26:42","AP01SDTM":"2020-01-07 08:26:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4639,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.98616,"AVALU":"mg/L","BASE2":8.82458,"BASE":9.98616,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.16158,"PCHG2":13.16295,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-07 08:26:42","ADY":121,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-149","SUBJID":"id-149","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.64074,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-03","TRTSDTM":"2020-01-07 08:26:42","TRT01SDTM":"2020-01-07 08:26:42","AP01SDTM":"2020-01-07 08:26:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6399,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.53462,"AVALU":"mg/L","BASE2":8.82458,"BASE":9.98616,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.28997,"PCHG2":-14.61787,"CHG":-2.45154,"PCHG":-24.5494,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-08-20 08:26:42","ADY":226,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-149","SUBJID":"id-149","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.64074,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-03","TRTSDTM":"2020-01-07 08:26:42","TRT01SDTM":"2020-01-07 08:26:42","AP01SDTM":"2020-01-07 08:26:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7087,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.22152,"AVALU":"mg/L","BASE2":8.82458,"BASE":9.98616,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.39694,"PCHG2":15.83008,"CHG":0.23536,"PCHG":2.35689,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-10-01 08:26:42","ADY":268,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-149","SUBJID":"id-149","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.64074,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-03","TRTSDTM":"2020-01-07 08:26:42","TRT01SDTM":"2020-01-07 08:26:42","AP01SDTM":"2020-01-07 08:26:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5531,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.01145,"AVALU":"mg/L","BASE2":8.82458,"BASE":9.98616,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18687,"PCHG2":2.11761,"CHG":-0.97471,"PCHG":-9.76056,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-31 08:26:42","ADY":390,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-149","SUBJID":"id-149","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.64074,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-03","TRTSDTM":"2020-01-07 08:26:42","TRT01SDTM":"2020-01-07 08:26:42","AP01SDTM":"2020-01-07 08:26:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4995,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.02604,"AVALU":"mg/L","BASE2":8.82458,"BASE":9.98616,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.20145,"PCHG2":2.28288,"CHG":-0.96012,"PCHG":-9.61452,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-07 08:26:42","ADY":578,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-149","SUBJID":"id-149","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.64074,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-03","TRTSDTM":"2020-01-07 08:26:42","TRT01SDTM":"2020-01-07 08:26:42","AP01SDTM":"2020-01-07 08:26:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4152,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.63633,"AVALU":"mg/L","BASE2":8.82458,"BASE":9.98616,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.81174,"PCHG2":20.53064,"CHG":0.65017,"PCHG":6.51069,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-12-10 08:26:42","ADY":703,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-149","SUBJID":"id-149","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.64074,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-03","TRTSDTM":"2020-01-07 08:26:42","TRT01SDTM":"2020-01-07 08:26:42","AP01SDTM":"2020-01-07 08:26:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6114,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82677,"AVALU":"g/L","BASE2":2.82677,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-01 08:26:42","ADY":85,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-149","SUBJID":"id-149","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.64074,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-03","TRTSDTM":"2020-01-07 08:26:42","TRT01SDTM":"2020-01-07 08:26:42","AP01SDTM":"2020-01-07 08:26:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5594,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94009,"AVALU":"g/L","BASE2":2.82677,"BASE":2.94009,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.11332,"PCHG2":4.00891,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-07 08:26:42","ADY":121,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-149","SUBJID":"id-149","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.64074,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-03","TRTSDTM":"2020-01-07 08:26:42","TRT01SDTM":"2020-01-07 08:26:42","AP01SDTM":"2020-01-07 08:26:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1863,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96788,"AVALU":"g/L","BASE2":2.82677,"BASE":2.94009,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14111,"PCHG2":4.99178,"CHG":0.02778,"PCHG":0.94499,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-20 08:26:42","ADY":226,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-149","SUBJID":"id-149","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.64074,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-03","TRTSDTM":"2020-01-07 08:26:42","TRT01SDTM":"2020-01-07 08:26:42","AP01SDTM":"2020-01-07 08:26:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4172,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82499,"AVALU":"g/L","BASE2":2.82677,"BASE":2.94009,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00179,"PCHG2":-0.06316,"CHG":-0.11511,"PCHG":-3.91511,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-01 08:26:42","ADY":268,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-149","SUBJID":"id-149","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.64074,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-03","TRTSDTM":"2020-01-07 08:26:42","TRT01SDTM":"2020-01-07 08:26:42","AP01SDTM":"2020-01-07 08:26:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4161,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81987,"AVALU":"g/L","BASE2":2.82677,"BASE":2.94009,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0069,"PCHG2":-0.24415,"CHG":-0.12022,"PCHG":-4.08913,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-31 08:26:42","ADY":390,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-149","SUBJID":"id-149","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.64074,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-03","TRTSDTM":"2020-01-07 08:26:42","TRT01SDTM":"2020-01-07 08:26:42","AP01SDTM":"2020-01-07 08:26:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1699,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80485,"AVALU":"g/L","BASE2":2.82677,"BASE":2.94009,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02193,"PCHG2":-0.77562,"CHG":-0.13525,"PCHG":-4.60012,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-07 08:26:42","ADY":578,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-149","SUBJID":"id-149","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":9.64074,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-03","TRTSDTM":"2020-01-07 08:26:42","TRT01SDTM":"2020-01-07 08:26:42","AP01SDTM":"2020-01-07 08:26:42","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6732,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92639,"AVALU":"g/L","BASE2":2.82677,"BASE":2.94009,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09962,"PCHG2":3.52423,"CHG":-0.0137,"PCHG":-0.466,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-10 08:26:42","ADY":703,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-22","SUBJID":"id-22","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.69016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-15 23:38:01","TRTEDTM":"2022-02-12 18:33:26","TRT01SDTM":"2021-01-15 23:38:01","TRT01EDTM":"2021-02-12 12:33:26","TRT02SDTM":"2021-02-12 12:33:26","TRT02EDTM":"2022-02-12 18:33:26","AP01SDTM":"2021-01-15 23:38:01","AP01EDTM":"2021-02-12 12:33:26","AP02SDTM":"2021-02-12 12:33:26","AP02EDTM":"2022-02-12 18:33:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":393,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":409,"ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5995,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.29361,"AVALU":"U/L","BASE2":3.29361,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-4","ADTM":"2021-04-04 23:38:01","ADY":79,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-22","SUBJID":"id-22","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.69016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-15 23:38:01","TRTEDTM":"2022-02-12 18:33:26","TRT01SDTM":"2021-01-15 23:38:01","TRT01EDTM":"2021-02-12 12:33:26","TRT02SDTM":"2021-02-12 12:33:26","TRT02EDTM":"2022-02-12 18:33:26","AP01SDTM":"2021-01-15 23:38:01","AP01EDTM":"2021-02-12 12:33:26","AP02SDTM":"2021-02-12 12:33:26","AP02EDTM":"2022-02-12 18:33:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":393,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":409,"ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":617,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.6724,"AVALU":"U/L","BASE2":3.29361,"BASE":0.6724,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.62121,"PCHG2":-79.58466,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-4","BTOXGR":"-4","ADTM":"2021-04-06 23:38:01","ADY":81,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-22","SUBJID":"id-22","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.69016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-15 23:38:01","TRTEDTM":"2022-02-12 18:33:26","TRT01SDTM":"2021-01-15 23:38:01","TRT01EDTM":"2021-02-12 12:33:26","TRT02SDTM":"2021-02-12 12:33:26","TRT02EDTM":"2022-02-12 18:33:26","AP01SDTM":"2021-01-15 23:38:01","AP01EDTM":"2021-02-12 12:33:26","AP02SDTM":"2021-02-12 12:33:26","AP02EDTM":"2022-02-12 18:33:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":393,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":409,"ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3999,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.56338,"AVALU":"U/L","BASE2":3.29361,"BASE":0.6724,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":25.26978,"PCHG2":767.23733,"CHG":27.89098,"PCHG":4147.96993,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-06-01 23:38:01","ADY":137,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-22","SUBJID":"id-22","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.69016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-15 23:38:01","TRTEDTM":"2022-02-12 18:33:26","TRT01SDTM":"2021-01-15 23:38:01","TRT01EDTM":"2021-02-12 12:33:26","TRT02SDTM":"2021-02-12 12:33:26","TRT02EDTM":"2022-02-12 18:33:26","AP01SDTM":"2021-01-15 23:38:01","AP01EDTM":"2021-02-12 12:33:26","AP02SDTM":"2021-02-12 12:33:26","AP02EDTM":"2022-02-12 18:33:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":393,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":409,"ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6541,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.04714,"AVALU":"U/L","BASE2":3.29361,"BASE":0.6724,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.75353,"PCHG2":296.13528,"CHG":12.37474,"PCHG":1840.38093,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-06-30 23:38:01","ADY":166,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-22","SUBJID":"id-22","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.69016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-15 23:38:01","TRTEDTM":"2022-02-12 18:33:26","TRT01SDTM":"2021-01-15 23:38:01","TRT01EDTM":"2021-02-12 12:33:26","TRT02SDTM":"2021-02-12 12:33:26","TRT02EDTM":"2022-02-12 18:33:26","AP01SDTM":"2021-01-15 23:38:01","AP01EDTM":"2021-02-12 12:33:26","AP02SDTM":"2021-02-12 12:33:26","AP02EDTM":"2022-02-12 18:33:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":393,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":409,"ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4854,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.52586,"AVALU":"U/L","BASE2":3.29361,"BASE":0.6724,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":20.23225,"PCHG2":614.28862,"CHG":22.85346,"PCHG":3398.78459,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-08-02 23:38:01","ADY":199,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-22","SUBJID":"id-22","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.69016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-15 23:38:01","TRTEDTM":"2022-02-12 18:33:26","TRT01SDTM":"2021-01-15 23:38:01","TRT01EDTM":"2021-02-12 12:33:26","TRT02SDTM":"2021-02-12 12:33:26","TRT02EDTM":"2022-02-12 18:33:26","AP01SDTM":"2021-01-15 23:38:01","AP01EDTM":"2021-02-12 12:33:26","AP02SDTM":"2021-02-12 12:33:26","AP02EDTM":"2022-02-12 18:33:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":393,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":409,"ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":426,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.52349,"AVALU":"U/L","BASE2":3.29361,"BASE":0.6724,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.22988,"PCHG2":280.23639,"CHG":11.85109,"PCHG":1762.50373,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-08-18 23:38:01","ADY":215,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-22","SUBJID":"id-22","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.69016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-15 23:38:01","TRTEDTM":"2022-02-12 18:33:26","TRT01SDTM":"2021-01-15 23:38:01","TRT01EDTM":"2021-02-12 12:33:26","TRT02SDTM":"2021-02-12 12:33:26","TRT02EDTM":"2022-02-12 18:33:26","AP01SDTM":"2021-01-15 23:38:01","AP01EDTM":"2021-02-12 12:33:26","AP02SDTM":"2021-02-12 12:33:26","AP02EDTM":"2022-02-12 18:33:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":393,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":409,"ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7076,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.78768,"AVALU":"U/L","BASE2":3.29361,"BASE":0.6724,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.49407,"PCHG2":591.87621,"CHG":22.11528,"PCHG":3289.00235,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-09-21 23:38:01","ADY":249,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-22","SUBJID":"id-22","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.69016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-15 23:38:01","TRTEDTM":"2022-02-12 18:33:26","TRT01SDTM":"2021-01-15 23:38:01","TRT01EDTM":"2021-02-12 12:33:26","TRT02SDTM":"2021-02-12 12:33:26","TRT02EDTM":"2022-02-12 18:33:26","AP01SDTM":"2021-01-15 23:38:01","AP01EDTM":"2021-02-12 12:33:26","AP02SDTM":"2021-02-12 12:33:26","AP02EDTM":"2022-02-12 18:33:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":393,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":409,"ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6591,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.01202,"AVALU":"mg/L","BASE2":8.01202,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-04 23:38:01","ADY":79,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-22","SUBJID":"id-22","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.69016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-15 23:38:01","TRTEDTM":"2022-02-12 18:33:26","TRT01SDTM":"2021-01-15 23:38:01","TRT01EDTM":"2021-02-12 12:33:26","TRT02SDTM":"2021-02-12 12:33:26","TRT02EDTM":"2022-02-12 18:33:26","AP01SDTM":"2021-01-15 23:38:01","AP01EDTM":"2021-02-12 12:33:26","AP02SDTM":"2021-02-12 12:33:26","AP02EDTM":"2022-02-12 18:33:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":393,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":409,"ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4851,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.89345,"AVALU":"mg/L","BASE2":8.01202,"BASE":9.89345,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.88143,"PCHG2":23.48252,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-06 23:38:01","ADY":81,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-22","SUBJID":"id-22","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.69016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-15 23:38:01","TRTEDTM":"2022-02-12 18:33:26","TRT01SDTM":"2021-01-15 23:38:01","TRT01EDTM":"2021-02-12 12:33:26","TRT02SDTM":"2021-02-12 12:33:26","TRT02EDTM":"2022-02-12 18:33:26","AP01SDTM":"2021-01-15 23:38:01","AP01EDTM":"2021-02-12 12:33:26","AP02SDTM":"2021-02-12 12:33:26","AP02EDTM":"2022-02-12 18:33:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":393,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":409,"ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2635,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.79369,"AVALU":"mg/L","BASE2":8.01202,"BASE":9.89345,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.78167,"PCHG2":9.75619,"CHG":-1.09976,"PCHG":-11.11601,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-01 23:38:01","ADY":137,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-22","SUBJID":"id-22","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.69016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-15 23:38:01","TRTEDTM":"2022-02-12 18:33:26","TRT01SDTM":"2021-01-15 23:38:01","TRT01EDTM":"2021-02-12 12:33:26","TRT02SDTM":"2021-02-12 12:33:26","TRT02EDTM":"2022-02-12 18:33:26","AP01SDTM":"2021-01-15 23:38:01","AP01EDTM":"2021-02-12 12:33:26","AP02SDTM":"2021-02-12 12:33:26","AP02EDTM":"2022-02-12 18:33:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":393,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":409,"ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3232,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.86942,"AVALU":"mg/L","BASE2":8.01202,"BASE":9.89345,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.1426,"PCHG2":-14.26112,"CHG":-3.02403,"PCHG":-30.56598,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-06-30 23:38:01","ADY":166,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-22","SUBJID":"id-22","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.69016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-15 23:38:01","TRTEDTM":"2022-02-12 18:33:26","TRT01SDTM":"2021-01-15 23:38:01","TRT01EDTM":"2021-02-12 12:33:26","TRT02SDTM":"2021-02-12 12:33:26","TRT02EDTM":"2022-02-12 18:33:26","AP01SDTM":"2021-01-15 23:38:01","AP01EDTM":"2021-02-12 12:33:26","AP02SDTM":"2021-02-12 12:33:26","AP02EDTM":"2022-02-12 18:33:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":393,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":409,"ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4932,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.8568,"AVALU":"mg/L","BASE2":8.01202,"BASE":9.89345,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.84477,"PCHG2":10.54382,"CHG":-1.03665,"PCHG":-10.47816,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-02 23:38:01","ADY":199,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-22","SUBJID":"id-22","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.69016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-15 23:38:01","TRTEDTM":"2022-02-12 18:33:26","TRT01SDTM":"2021-01-15 23:38:01","TRT01EDTM":"2021-02-12 12:33:26","TRT02SDTM":"2021-02-12 12:33:26","TRT02EDTM":"2022-02-12 18:33:26","AP01SDTM":"2021-01-15 23:38:01","AP01EDTM":"2021-02-12 12:33:26","AP02SDTM":"2021-02-12 12:33:26","AP02EDTM":"2022-02-12 18:33:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":393,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":409,"ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2567,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.24959,"AVALU":"mg/L","BASE2":8.01202,"BASE":9.89345,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.23757,"PCHG2":15.44636,"CHG":-0.64386,"PCHG":-6.50793,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-18 23:38:01","ADY":215,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-22","SUBJID":"id-22","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.69016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-15 23:38:01","TRTEDTM":"2022-02-12 18:33:26","TRT01SDTM":"2021-01-15 23:38:01","TRT01EDTM":"2021-02-12 12:33:26","TRT02SDTM":"2021-02-12 12:33:26","TRT02EDTM":"2022-02-12 18:33:26","AP01SDTM":"2021-01-15 23:38:01","AP01EDTM":"2021-02-12 12:33:26","AP02SDTM":"2021-02-12 12:33:26","AP02EDTM":"2022-02-12 18:33:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":393,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":409,"ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5552,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.87864,"AVALU":"mg/L","BASE2":8.01202,"BASE":9.89345,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.86662,"PCHG2":23.29768,"CHG":-0.01481,"PCHG":-0.14969,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-21 23:38:01","ADY":249,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-22","SUBJID":"id-22","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.69016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-15 23:38:01","TRTEDTM":"2022-02-12 18:33:26","TRT01SDTM":"2021-01-15 23:38:01","TRT01EDTM":"2021-02-12 12:33:26","TRT02SDTM":"2021-02-12 12:33:26","TRT02EDTM":"2022-02-12 18:33:26","AP01SDTM":"2021-01-15 23:38:01","AP01EDTM":"2021-02-12 12:33:26","AP02SDTM":"2021-02-12 12:33:26","AP02EDTM":"2022-02-12 18:33:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":393,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":409,"ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":123,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84044,"AVALU":"g/L","BASE2":2.84044,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-04 23:38:01","ADY":79,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-22","SUBJID":"id-22","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.69016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-15 23:38:01","TRTEDTM":"2022-02-12 18:33:26","TRT01SDTM":"2021-01-15 23:38:01","TRT01EDTM":"2021-02-12 12:33:26","TRT02SDTM":"2021-02-12 12:33:26","TRT02EDTM":"2022-02-12 18:33:26","AP01SDTM":"2021-01-15 23:38:01","AP01EDTM":"2021-02-12 12:33:26","AP02SDTM":"2021-02-12 12:33:26","AP02EDTM":"2022-02-12 18:33:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":393,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":409,"ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4846,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88083,"AVALU":"g/L","BASE2":2.84044,"BASE":2.88083,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.04039,"PCHG2":1.42196,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-06 23:38:01","ADY":81,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-22","SUBJID":"id-22","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.69016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-15 23:38:01","TRTEDTM":"2022-02-12 18:33:26","TRT01SDTM":"2021-01-15 23:38:01","TRT01EDTM":"2021-02-12 12:33:26","TRT02SDTM":"2021-02-12 12:33:26","TRT02EDTM":"2022-02-12 18:33:26","AP01SDTM":"2021-01-15 23:38:01","AP01EDTM":"2021-02-12 12:33:26","AP02SDTM":"2021-02-12 12:33:26","AP02EDTM":"2022-02-12 18:33:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":393,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":409,"ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4894,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95828,"AVALU":"g/L","BASE2":2.84044,"BASE":2.88083,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11783,"PCHG2":4.14835,"CHG":0.07744,"PCHG":2.68816,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-01 23:38:01","ADY":137,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-22","SUBJID":"id-22","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.69016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-15 23:38:01","TRTEDTM":"2022-02-12 18:33:26","TRT01SDTM":"2021-01-15 23:38:01","TRT01EDTM":"2021-02-12 12:33:26","TRT02SDTM":"2021-02-12 12:33:26","TRT02EDTM":"2022-02-12 18:33:26","AP01SDTM":"2021-01-15 23:38:01","AP01EDTM":"2021-02-12 12:33:26","AP02SDTM":"2021-02-12 12:33:26","AP02EDTM":"2022-02-12 18:33:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":393,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":409,"ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2607,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81587,"AVALU":"g/L","BASE2":2.84044,"BASE":2.88083,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02457,"PCHG2":-0.86508,"CHG":-0.06496,"PCHG":-2.25498,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-30 23:38:01","ADY":166,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-22","SUBJID":"id-22","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.69016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-15 23:38:01","TRTEDTM":"2022-02-12 18:33:26","TRT01SDTM":"2021-01-15 23:38:01","TRT01EDTM":"2021-02-12 12:33:26","TRT02SDTM":"2021-02-12 12:33:26","TRT02EDTM":"2022-02-12 18:33:26","AP01SDTM":"2021-01-15 23:38:01","AP01EDTM":"2021-02-12 12:33:26","AP02SDTM":"2021-02-12 12:33:26","AP02EDTM":"2022-02-12 18:33:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":393,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":409,"ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5246,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92923,"AVALU":"g/L","BASE2":2.84044,"BASE":2.88083,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08879,"PCHG2":3.12583,"CHG":0.0484,"PCHG":1.67998,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-02 23:38:01","ADY":199,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-22","SUBJID":"id-22","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.69016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-15 23:38:01","TRTEDTM":"2022-02-12 18:33:26","TRT01SDTM":"2021-01-15 23:38:01","TRT01EDTM":"2021-02-12 12:33:26","TRT02SDTM":"2021-02-12 12:33:26","TRT02EDTM":"2022-02-12 18:33:26","AP01SDTM":"2021-01-15 23:38:01","AP01EDTM":"2021-02-12 12:33:26","AP02SDTM":"2021-02-12 12:33:26","AP02EDTM":"2022-02-12 18:33:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":393,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":409,"ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4725,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98734,"AVALU":"g/L","BASE2":2.84044,"BASE":2.88083,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14689,"PCHG2":5.17145,"CHG":0.1065,"PCHG":3.69692,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-18 23:38:01","ADY":215,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-22","SUBJID":"id-22","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.69016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-15 23:38:01","TRTEDTM":"2022-02-12 18:33:26","TRT01SDTM":"2021-01-15 23:38:01","TRT01EDTM":"2021-02-12 12:33:26","TRT02SDTM":"2021-02-12 12:33:26","TRT02EDTM":"2022-02-12 18:33:26","AP01SDTM":"2021-01-15 23:38:01","AP01EDTM":"2021-02-12 12:33:26","AP02SDTM":"2021-02-12 12:33:26","AP02EDTM":"2022-02-12 18:33:26","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":393,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":409,"ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2802,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94583,"AVALU":"g/L","BASE2":2.84044,"BASE":2.88083,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10539,"PCHG2":3.71032,"CHG":0.065,"PCHG":2.25627,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-21 23:38:01","ADY":249,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-223","SUBJID":"id-223","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.62508,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-18 10:22:36","TRTEDTM":"2022-02-13 16:30:19","TRT01SDTM":"2020-11-18 10:22:36","TRT01EDTM":"2021-02-13 10:30:19","TRT02SDTM":"2021-02-13 10:30:19","TRT02EDTM":"2022-02-13 16:30:19","AP01SDTM":"2020-11-18 10:22:36","AP01EDTM":"2021-02-13 10:30:19","AP02SDTM":"2021-02-13 10:30:19","AP02EDTM":"2022-02-13 16:30:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":453,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":468,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1436,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.77892,"AVALU":"U/L","BASE2":33.77892,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-08 10:22:36","ADY":20,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-223","SUBJID":"id-223","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.62508,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-18 10:22:36","TRTEDTM":"2022-02-13 16:30:19","TRT01SDTM":"2020-11-18 10:22:36","TRT01EDTM":"2021-02-13 10:30:19","TRT02SDTM":"2021-02-13 10:30:19","TRT02EDTM":"2022-02-13 16:30:19","AP01SDTM":"2020-11-18 10:22:36","AP01EDTM":"2021-02-13 10:30:19","AP02SDTM":"2021-02-13 10:30:19","AP02EDTM":"2022-02-13 16:30:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":453,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":468,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4206,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.01573,"AVALU":"U/L","BASE2":33.77892,"BASE":26.01573,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-7.76319,"PCHG2":-22.98236,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-10 10:22:36","ADY":84,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-223","SUBJID":"id-223","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.62508,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-18 10:22:36","TRTEDTM":"2022-02-13 16:30:19","TRT01SDTM":"2020-11-18 10:22:36","TRT01EDTM":"2021-02-13 10:30:19","TRT02SDTM":"2021-02-13 10:30:19","TRT02EDTM":"2022-02-13 16:30:19","AP01SDTM":"2020-11-18 10:22:36","AP01EDTM":"2021-02-13 10:30:19","AP02SDTM":"2021-02-13 10:30:19","AP02EDTM":"2022-02-13 16:30:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":453,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":468,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4255,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.03411,"AVALU":"U/L","BASE2":33.77892,"BASE":26.01573,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.74481,"PCHG2":-40.6905,"CHG":-5.98162,"PCHG":-22.99232,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-15 10:22:36","ADY":117,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-223","SUBJID":"id-223","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.62508,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-18 10:22:36","TRTEDTM":"2022-02-13 16:30:19","TRT01SDTM":"2020-11-18 10:22:36","TRT01EDTM":"2021-02-13 10:30:19","TRT02SDTM":"2021-02-13 10:30:19","TRT02EDTM":"2022-02-13 16:30:19","AP01SDTM":"2020-11-18 10:22:36","AP01EDTM":"2021-02-13 10:30:19","AP02SDTM":"2021-02-13 10:30:19","AP02EDTM":"2022-02-13 16:30:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":453,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":468,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5929,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.37006,"AVALU":"U/L","BASE2":33.77892,"BASE":26.01573,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.40886,"PCHG2":-51.53764,"CHG":-9.64567,"PCHG":-37.07629,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-24 10:22:36","ADY":126,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-223","SUBJID":"id-223","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.62508,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-18 10:22:36","TRTEDTM":"2022-02-13 16:30:19","TRT01SDTM":"2020-11-18 10:22:36","TRT01EDTM":"2021-02-13 10:30:19","TRT02SDTM":"2021-02-13 10:30:19","TRT02EDTM":"2022-02-13 16:30:19","AP01SDTM":"2020-11-18 10:22:36","AP01EDTM":"2021-02-13 10:30:19","AP02SDTM":"2021-02-13 10:30:19","AP02EDTM":"2022-02-13 16:30:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":453,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":468,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4608,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.9425,"AVALU":"U/L","BASE2":33.77892,"BASE":26.01573,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.83641,"PCHG2":-40.96169,"CHG":-6.07322,"PCHG":-23.34443,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-17 10:22:36","ADY":211,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-223","SUBJID":"id-223","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.62508,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-18 10:22:36","TRTEDTM":"2022-02-13 16:30:19","TRT01SDTM":"2020-11-18 10:22:36","TRT01EDTM":"2021-02-13 10:30:19","TRT02SDTM":"2021-02-13 10:30:19","TRT02EDTM":"2022-02-13 16:30:19","AP01SDTM":"2020-11-18 10:22:36","AP01EDTM":"2021-02-13 10:30:19","AP02SDTM":"2021-02-13 10:30:19","AP02EDTM":"2022-02-13 16:30:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":453,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":468,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7573,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.11006,"AVALU":"U/L","BASE2":33.77892,"BASE":26.01573,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.66886,"PCHG2":-22.70309,"CHG":0.09433,"PCHG":0.3626,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-04 10:22:36","ADY":259,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-223","SUBJID":"id-223","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.62508,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-18 10:22:36","TRTEDTM":"2022-02-13 16:30:19","TRT01SDTM":"2020-11-18 10:22:36","TRT01EDTM":"2021-02-13 10:30:19","TRT02SDTM":"2021-02-13 10:30:19","TRT02EDTM":"2022-02-13 16:30:19","AP01SDTM":"2020-11-18 10:22:36","AP01EDTM":"2021-02-13 10:30:19","AP02SDTM":"2021-02-13 10:30:19","AP02EDTM":"2022-02-13 16:30:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":453,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":468,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2235,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.66325,"AVALU":"U/L","BASE2":33.77892,"BASE":26.01573,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11567,"PCHG2":-0.34244,"CHG":7.64752,"PCHG":29.39576,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-07 10:22:36","ADY":354,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-223","SUBJID":"id-223","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.62508,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-18 10:22:36","TRTEDTM":"2022-02-13 16:30:19","TRT01SDTM":"2020-11-18 10:22:36","TRT01EDTM":"2021-02-13 10:30:19","TRT02SDTM":"2021-02-13 10:30:19","TRT02EDTM":"2022-02-13 16:30:19","AP01SDTM":"2020-11-18 10:22:36","AP01EDTM":"2021-02-13 10:30:19","AP02SDTM":"2021-02-13 10:30:19","AP02EDTM":"2022-02-13 16:30:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":453,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":468,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5252,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.14914,"AVALU":"mg/L","BASE2":9.14914,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-08 10:22:36","ADY":20,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-223","SUBJID":"id-223","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.62508,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-18 10:22:36","TRTEDTM":"2022-02-13 16:30:19","TRT01SDTM":"2020-11-18 10:22:36","TRT01EDTM":"2021-02-13 10:30:19","TRT02SDTM":"2021-02-13 10:30:19","TRT02EDTM":"2022-02-13 16:30:19","AP01SDTM":"2020-11-18 10:22:36","AP01EDTM":"2021-02-13 10:30:19","AP02SDTM":"2021-02-13 10:30:19","AP02EDTM":"2022-02-13 16:30:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":453,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":468,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6428,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.65467,"AVALU":"mg/L","BASE2":9.14914,"BASE":8.65467,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.49447,"PCHG2":-5.40456,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-10 10:22:36","ADY":84,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-223","SUBJID":"id-223","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.62508,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-18 10:22:36","TRTEDTM":"2022-02-13 16:30:19","TRT01SDTM":"2020-11-18 10:22:36","TRT01EDTM":"2021-02-13 10:30:19","TRT02SDTM":"2021-02-13 10:30:19","TRT02EDTM":"2022-02-13 16:30:19","AP01SDTM":"2020-11-18 10:22:36","AP01EDTM":"2021-02-13 10:30:19","AP02SDTM":"2021-02-13 10:30:19","AP02EDTM":"2022-02-13 16:30:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":453,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":468,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7420,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.7237,"AVALU":"mg/L","BASE2":9.14914,"BASE":8.65467,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.42544,"PCHG2":-4.65002,"CHG":0.06903,"PCHG":0.79765,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-15 10:22:36","ADY":117,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-223","SUBJID":"id-223","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.62508,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-18 10:22:36","TRTEDTM":"2022-02-13 16:30:19","TRT01SDTM":"2020-11-18 10:22:36","TRT01EDTM":"2021-02-13 10:30:19","TRT02SDTM":"2021-02-13 10:30:19","TRT02EDTM":"2022-02-13 16:30:19","AP01SDTM":"2020-11-18 10:22:36","AP01EDTM":"2021-02-13 10:30:19","AP02SDTM":"2021-02-13 10:30:19","AP02EDTM":"2022-02-13 16:30:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":453,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":468,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5663,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.00294,"AVALU":"mg/L","BASE2":9.14914,"BASE":8.65467,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.1462,"PCHG2":-12.52791,"CHG":-0.65172,"PCHG":-7.53032,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-24 10:22:36","ADY":126,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-223","SUBJID":"id-223","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.62508,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-18 10:22:36","TRTEDTM":"2022-02-13 16:30:19","TRT01SDTM":"2020-11-18 10:22:36","TRT01EDTM":"2021-02-13 10:30:19","TRT02SDTM":"2021-02-13 10:30:19","TRT02EDTM":"2022-02-13 16:30:19","AP01SDTM":"2020-11-18 10:22:36","AP01EDTM":"2021-02-13 10:30:19","AP02SDTM":"2021-02-13 10:30:19","AP02EDTM":"2022-02-13 16:30:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":453,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":468,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2989,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.45647,"AVALU":"mg/L","BASE2":9.14914,"BASE":8.65467,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.30734,"PCHG2":14.28917,"CHG":1.80181,"PCHG":20.8189,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-06-17 10:22:36","ADY":211,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-223","SUBJID":"id-223","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.62508,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-18 10:22:36","TRTEDTM":"2022-02-13 16:30:19","TRT01SDTM":"2020-11-18 10:22:36","TRT01EDTM":"2021-02-13 10:30:19","TRT02SDTM":"2021-02-13 10:30:19","TRT02EDTM":"2022-02-13 16:30:19","AP01SDTM":"2020-11-18 10:22:36","AP01EDTM":"2021-02-13 10:30:19","AP02SDTM":"2021-02-13 10:30:19","AP02EDTM":"2022-02-13 16:30:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":453,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":468,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4510,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.47334,"AVALU":"mg/L","BASE2":9.14914,"BASE":8.65467,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.6758,"PCHG2":-7.38648,"CHG":-0.18133,"PCHG":-2.09515,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-04 10:22:36","ADY":259,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-223","SUBJID":"id-223","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.62508,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-18 10:22:36","TRTEDTM":"2022-02-13 16:30:19","TRT01SDTM":"2020-11-18 10:22:36","TRT01EDTM":"2021-02-13 10:30:19","TRT02SDTM":"2021-02-13 10:30:19","TRT02EDTM":"2022-02-13 16:30:19","AP01SDTM":"2020-11-18 10:22:36","AP01EDTM":"2021-02-13 10:30:19","AP02SDTM":"2021-02-13 10:30:19","AP02EDTM":"2022-02-13 16:30:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":453,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":468,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4110,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.27423,"AVALU":"mg/L","BASE2":9.14914,"BASE":8.65467,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12509,"PCHG2":1.36724,"CHG":0.61956,"PCHG":7.1587,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-07 10:22:36","ADY":354,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-223","SUBJID":"id-223","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.62508,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-18 10:22:36","TRTEDTM":"2022-02-13 16:30:19","TRT01SDTM":"2020-11-18 10:22:36","TRT01EDTM":"2021-02-13 10:30:19","TRT02SDTM":"2021-02-13 10:30:19","TRT02EDTM":"2022-02-13 16:30:19","AP01SDTM":"2020-11-18 10:22:36","AP01EDTM":"2021-02-13 10:30:19","AP02SDTM":"2021-02-13 10:30:19","AP02EDTM":"2022-02-13 16:30:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":453,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":468,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1895,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79864,"AVALU":"g/L","BASE2":2.79864,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-08 10:22:36","ADY":20,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-223","SUBJID":"id-223","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.62508,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-18 10:22:36","TRTEDTM":"2022-02-13 16:30:19","TRT01SDTM":"2020-11-18 10:22:36","TRT01EDTM":"2021-02-13 10:30:19","TRT02SDTM":"2021-02-13 10:30:19","TRT02EDTM":"2022-02-13 16:30:19","AP01SDTM":"2020-11-18 10:22:36","AP01EDTM":"2021-02-13 10:30:19","AP02SDTM":"2021-02-13 10:30:19","AP02EDTM":"2022-02-13 16:30:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":453,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":468,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2384,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8234,"AVALU":"g/L","BASE2":2.79864,"BASE":2.8234,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.02477,"PCHG2":0.88491,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-10 10:22:36","ADY":84,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-223","SUBJID":"id-223","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.62508,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-18 10:22:36","TRTEDTM":"2022-02-13 16:30:19","TRT01SDTM":"2020-11-18 10:22:36","TRT01EDTM":"2021-02-13 10:30:19","TRT02SDTM":"2021-02-13 10:30:19","TRT02EDTM":"2022-02-13 16:30:19","AP01SDTM":"2020-11-18 10:22:36","AP01EDTM":"2021-02-13 10:30:19","AP02SDTM":"2021-02-13 10:30:19","AP02EDTM":"2022-02-13 16:30:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":453,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":468,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5736,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87022,"AVALU":"g/L","BASE2":2.79864,"BASE":2.8234,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07158,"PCHG2":2.5577,"CHG":0.04682,"PCHG":1.65812,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-15 10:22:36","ADY":117,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-223","SUBJID":"id-223","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.62508,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-18 10:22:36","TRTEDTM":"2022-02-13 16:30:19","TRT01SDTM":"2020-11-18 10:22:36","TRT01EDTM":"2021-02-13 10:30:19","TRT02SDTM":"2021-02-13 10:30:19","TRT02EDTM":"2022-02-13 16:30:19","AP01SDTM":"2020-11-18 10:22:36","AP01EDTM":"2021-02-13 10:30:19","AP02SDTM":"2021-02-13 10:30:19","AP02EDTM":"2022-02-13 16:30:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":453,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":468,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3871,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.72179,"AVALU":"g/L","BASE2":2.79864,"BASE":2.8234,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07685,"PCHG2":-2.74599,"CHG":-0.10162,"PCHG":-3.59905,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-24 10:22:36","ADY":126,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-223","SUBJID":"id-223","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.62508,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-18 10:22:36","TRTEDTM":"2022-02-13 16:30:19","TRT01SDTM":"2020-11-18 10:22:36","TRT01EDTM":"2021-02-13 10:30:19","TRT02SDTM":"2021-02-13 10:30:19","TRT02EDTM":"2022-02-13 16:30:19","AP01SDTM":"2020-11-18 10:22:36","AP01EDTM":"2021-02-13 10:30:19","AP02SDTM":"2021-02-13 10:30:19","AP02EDTM":"2022-02-13 16:30:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":453,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":468,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":676,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.69112,"AVALU":"g/L","BASE2":2.79864,"BASE":2.8234,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10751,"PCHG2":-3.84155,"CHG":-0.13228,"PCHG":-4.685,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-17 10:22:36","ADY":211,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-223","SUBJID":"id-223","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.62508,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-18 10:22:36","TRTEDTM":"2022-02-13 16:30:19","TRT01SDTM":"2020-11-18 10:22:36","TRT01EDTM":"2021-02-13 10:30:19","TRT02SDTM":"2021-02-13 10:30:19","TRT02EDTM":"2022-02-13 16:30:19","AP01SDTM":"2020-11-18 10:22:36","AP01EDTM":"2021-02-13 10:30:19","AP02SDTM":"2021-02-13 10:30:19","AP02EDTM":"2022-02-13 16:30:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":453,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":468,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4902,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99859,"AVALU":"g/L","BASE2":2.79864,"BASE":2.8234,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.19996,"PCHG2":7.14484,"CHG":0.17519,"PCHG":6.20502,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-04 10:22:36","ADY":259,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-223","SUBJID":"id-223","SITEID":"CHN-2","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.62508,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-18 10:22:36","TRTEDTM":"2022-02-13 16:30:19","TRT01SDTM":"2020-11-18 10:22:36","TRT01EDTM":"2021-02-13 10:30:19","TRT02SDTM":"2021-02-13 10:30:19","TRT02EDTM":"2022-02-13 16:30:19","AP01SDTM":"2020-11-18 10:22:36","AP01EDTM":"2021-02-13 10:30:19","AP02SDTM":"2021-02-13 10:30:19","AP02EDTM":"2022-02-13 16:30:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":453,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":17,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":468,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2555,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78185,"AVALU":"g/L","BASE2":2.79864,"BASE":2.8234,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01679,"PCHG2":-0.59981,"CHG":-0.04155,"PCHG":-1.47169,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-07 10:22:36","ADY":354,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-272","SUBJID":"id-272","SITEID":"CHN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.17023,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-08","TRTSDTM":"2020-01-11 03:34:36","TRTEDTM":"2022-02-16 23:45:28","TRT01SDTM":"2020-01-11 03:34:36","TRT01EDTM":"2021-02-16 17:45:28","TRT02SDTM":"2021-02-16 17:45:28","TRT02EDTM":"2022-02-16 23:45:28","AP01SDTM":"2020-01-11 03:34:36","AP01EDTM":"2021-02-16 17:45:28","AP02SDTM":"2021-02-16 17:45:28","AP02EDTM":"2022-02-16 23:45:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":768,"DCSREAS":"DEATH","DTHDT":"2022-02-23","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-23","DTHADY":773,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6722,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.65274,"AVALU":"U/L","BASE2":17.65274,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-01 03:34:36","ADY":81,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-272","SUBJID":"id-272","SITEID":"CHN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.17023,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-08","TRTSDTM":"2020-01-11 03:34:36","TRTEDTM":"2022-02-16 23:45:28","TRT01SDTM":"2020-01-11 03:34:36","TRT01EDTM":"2021-02-16 17:45:28","TRT02SDTM":"2021-02-16 17:45:28","TRT02EDTM":"2022-02-16 23:45:28","AP01SDTM":"2020-01-11 03:34:36","AP01EDTM":"2021-02-16 17:45:28","AP02SDTM":"2021-02-16 17:45:28","AP02EDTM":"2022-02-16 23:45:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":768,"DCSREAS":"DEATH","DTHDT":"2022-02-23","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-23","DTHADY":773,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7851,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.43502,"AVALU":"U/L","BASE2":17.65274,"BASE":20.43502,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.78228,"PCHG2":15.76118,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-07 03:34:36","ADY":87,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-272","SUBJID":"id-272","SITEID":"CHN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.17023,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-08","TRTSDTM":"2020-01-11 03:34:36","TRTEDTM":"2022-02-16 23:45:28","TRT01SDTM":"2020-01-11 03:34:36","TRT01EDTM":"2021-02-16 17:45:28","TRT02SDTM":"2021-02-16 17:45:28","TRT02EDTM":"2022-02-16 23:45:28","AP01SDTM":"2020-01-11 03:34:36","AP01EDTM":"2021-02-16 17:45:28","AP02SDTM":"2021-02-16 17:45:28","AP02EDTM":"2022-02-16 23:45:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":768,"DCSREAS":"DEATH","DTHDT":"2022-02-23","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-23","DTHADY":773,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":54,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.28316,"AVALU":"U/L","BASE2":17.65274,"BASE":20.43502,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.36958,"PCHG2":-19.08814,"CHG":-6.15186,"PCHG":-30.1045,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-18 03:34:36","ADY":220,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-272","SUBJID":"id-272","SITEID":"CHN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.17023,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-08","TRTSDTM":"2020-01-11 03:34:36","TRTEDTM":"2022-02-16 23:45:28","TRT01SDTM":"2020-01-11 03:34:36","TRT01EDTM":"2021-02-16 17:45:28","TRT02SDTM":"2021-02-16 17:45:28","TRT02EDTM":"2022-02-16 23:45:28","AP01SDTM":"2020-01-11 03:34:36","AP01EDTM":"2021-02-16 17:45:28","AP02SDTM":"2021-02-16 17:45:28","AP02EDTM":"2022-02-16 23:45:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":768,"DCSREAS":"DEATH","DTHDT":"2022-02-23","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-23","DTHADY":773,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5300,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.71486,"AVALU":"U/L","BASE2":17.65274,"BASE":20.43502,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.06212,"PCHG2":34.34094,"CHG":3.27984,"PCHG":16.05007,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-08 03:34:36","ADY":332,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-272","SUBJID":"id-272","SITEID":"CHN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.17023,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-08","TRTSDTM":"2020-01-11 03:34:36","TRTEDTM":"2022-02-16 23:45:28","TRT01SDTM":"2020-01-11 03:34:36","TRT01EDTM":"2021-02-16 17:45:28","TRT02SDTM":"2021-02-16 17:45:28","TRT02EDTM":"2022-02-16 23:45:28","AP01SDTM":"2020-01-11 03:34:36","AP01EDTM":"2021-02-16 17:45:28","AP02SDTM":"2021-02-16 17:45:28","AP02EDTM":"2022-02-16 23:45:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":768,"DCSREAS":"DEATH","DTHDT":"2022-02-23","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-23","DTHADY":773,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7809,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.23024,"AVALU":"U/L","BASE2":17.65274,"BASE":20.43502,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.5775,"PCHG2":20.26595,"CHG":0.79522,"PCHG":3.89143,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-16 03:34:36","ADY":340,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-272","SUBJID":"id-272","SITEID":"CHN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.17023,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-08","TRTSDTM":"2020-01-11 03:34:36","TRTEDTM":"2022-02-16 23:45:28","TRT01SDTM":"2020-01-11 03:34:36","TRT01EDTM":"2021-02-16 17:45:28","TRT02SDTM":"2021-02-16 17:45:28","TRT02EDTM":"2022-02-16 23:45:28","AP01SDTM":"2020-01-11 03:34:36","AP01EDTM":"2021-02-16 17:45:28","AP02SDTM":"2021-02-16 17:45:28","AP02EDTM":"2022-02-16 23:45:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":768,"DCSREAS":"DEATH","DTHDT":"2022-02-23","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-23","DTHADY":773,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2734,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.41001,"AVALU":"U/L","BASE2":17.65274,"BASE":20.43502,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.75727,"PCHG2":66.60311,"CHG":8.97499,"PCHG":43.91966,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-12 03:34:36","ADY":398,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-272","SUBJID":"id-272","SITEID":"CHN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.17023,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-08","TRTSDTM":"2020-01-11 03:34:36","TRTEDTM":"2022-02-16 23:45:28","TRT01SDTM":"2020-01-11 03:34:36","TRT01EDTM":"2021-02-16 17:45:28","TRT02SDTM":"2021-02-16 17:45:28","TRT02EDTM":"2022-02-16 23:45:28","AP01SDTM":"2020-01-11 03:34:36","AP01EDTM":"2021-02-16 17:45:28","AP02SDTM":"2021-02-16 17:45:28","AP02EDTM":"2022-02-16 23:45:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":768,"DCSREAS":"DEATH","DTHDT":"2022-02-23","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-23","DTHADY":773,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7446,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.63405,"AVALU":"U/L","BASE2":17.65274,"BASE":20.43502,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.01869,"PCHG2":-73.74885,"CHG":-15.80097,"PCHG":-77.32301,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-05-09 03:34:36","ADY":484,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-272","SUBJID":"id-272","SITEID":"CHN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.17023,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-08","TRTSDTM":"2020-01-11 03:34:36","TRTEDTM":"2022-02-16 23:45:28","TRT01SDTM":"2020-01-11 03:34:36","TRT01EDTM":"2021-02-16 17:45:28","TRT02SDTM":"2021-02-16 17:45:28","TRT02EDTM":"2022-02-16 23:45:28","AP01SDTM":"2020-01-11 03:34:36","AP01EDTM":"2021-02-16 17:45:28","AP02SDTM":"2021-02-16 17:45:28","AP02EDTM":"2022-02-16 23:45:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":768,"DCSREAS":"DEATH","DTHDT":"2022-02-23","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-23","DTHADY":773,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1423,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.49416,"AVALU":"mg/L","BASE2":9.49416,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-04-01 03:34:36","ADY":81,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-272","SUBJID":"id-272","SITEID":"CHN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.17023,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-08","TRTSDTM":"2020-01-11 03:34:36","TRTEDTM":"2022-02-16 23:45:28","TRT01SDTM":"2020-01-11 03:34:36","TRT01EDTM":"2021-02-16 17:45:28","TRT02SDTM":"2021-02-16 17:45:28","TRT02EDTM":"2022-02-16 23:45:28","AP01SDTM":"2020-01-11 03:34:36","AP01EDTM":"2021-02-16 17:45:28","AP02SDTM":"2021-02-16 17:45:28","AP02EDTM":"2022-02-16 23:45:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":768,"DCSREAS":"DEATH","DTHDT":"2022-02-23","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-23","DTHADY":773,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2295,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.78759,"AVALU":"mg/L","BASE2":9.49416,"BASE":10.78759,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.29343,"PCHG2":13.62344,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2020-04-07 03:34:36","ADY":87,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-272","SUBJID":"id-272","SITEID":"CHN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.17023,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-08","TRTSDTM":"2020-01-11 03:34:36","TRTEDTM":"2022-02-16 23:45:28","TRT01SDTM":"2020-01-11 03:34:36","TRT01EDTM":"2021-02-16 17:45:28","TRT02SDTM":"2021-02-16 17:45:28","TRT02EDTM":"2022-02-16 23:45:28","AP01SDTM":"2020-01-11 03:34:36","AP01EDTM":"2021-02-16 17:45:28","AP02SDTM":"2021-02-16 17:45:28","AP02EDTM":"2022-02-16 23:45:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":768,"DCSREAS":"DEATH","DTHDT":"2022-02-23","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-23","DTHADY":773,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2853,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.23168,"AVALU":"mg/L","BASE2":9.49416,"BASE":10.78759,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.26248,"PCHG2":-23.83019,"CHG":-3.55591,"PCHG":-32.96294,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-3","BTOXGR":"3","ADTM":"2020-08-18 03:34:36","ADY":220,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-272","SUBJID":"id-272","SITEID":"CHN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.17023,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-08","TRTSDTM":"2020-01-11 03:34:36","TRTEDTM":"2022-02-16 23:45:28","TRT01SDTM":"2020-01-11 03:34:36","TRT01EDTM":"2021-02-16 17:45:28","TRT02SDTM":"2021-02-16 17:45:28","TRT02EDTM":"2022-02-16 23:45:28","AP01SDTM":"2020-01-11 03:34:36","AP01EDTM":"2021-02-16 17:45:28","AP02SDTM":"2021-02-16 17:45:28","AP02EDTM":"2022-02-16 23:45:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":768,"DCSREAS":"DEATH","DTHDT":"2022-02-23","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-23","DTHADY":773,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2822,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.00979,"AVALU":"mg/L","BASE2":9.49416,"BASE":10.78759,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.48437,"PCHG2":-5.10173,"CHG":-1.7778,"PCHG":-16.48002,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-12-08 03:34:36","ADY":332,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-272","SUBJID":"id-272","SITEID":"CHN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.17023,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-08","TRTSDTM":"2020-01-11 03:34:36","TRTEDTM":"2022-02-16 23:45:28","TRT01SDTM":"2020-01-11 03:34:36","TRT01EDTM":"2021-02-16 17:45:28","TRT02SDTM":"2021-02-16 17:45:28","TRT02EDTM":"2022-02-16 23:45:28","AP01SDTM":"2020-01-11 03:34:36","AP01EDTM":"2021-02-16 17:45:28","AP02SDTM":"2021-02-16 17:45:28","AP02EDTM":"2022-02-16 23:45:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":768,"DCSREAS":"DEATH","DTHDT":"2022-02-23","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-23","DTHADY":773,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4922,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.87711,"AVALU":"mg/L","BASE2":9.49416,"BASE":10.78759,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.61705,"PCHG2":-17.03208,"CHG":-2.91048,"PCHG":-26.97992,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-1","BTOXGR":"3","ADTM":"2020-12-16 03:34:36","ADY":340,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-272","SUBJID":"id-272","SITEID":"CHN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.17023,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-08","TRTSDTM":"2020-01-11 03:34:36","TRTEDTM":"2022-02-16 23:45:28","TRT01SDTM":"2020-01-11 03:34:36","TRT01EDTM":"2021-02-16 17:45:28","TRT02SDTM":"2021-02-16 17:45:28","TRT02EDTM":"2022-02-16 23:45:28","AP01SDTM":"2020-01-11 03:34:36","AP01EDTM":"2021-02-16 17:45:28","AP02SDTM":"2021-02-16 17:45:28","AP02EDTM":"2022-02-16 23:45:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":768,"DCSREAS":"DEATH","DTHDT":"2022-02-23","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-23","DTHADY":773,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1169,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.48595,"AVALU":"mg/L","BASE2":9.49416,"BASE":10.78759,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0082,"PCHG2":-0.08642,"CHG":-1.30164,"PCHG":-12.06604,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-02-12 03:34:36","ADY":398,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-272","SUBJID":"id-272","SITEID":"CHN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.17023,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-08","TRTSDTM":"2020-01-11 03:34:36","TRTEDTM":"2022-02-16 23:45:28","TRT01SDTM":"2020-01-11 03:34:36","TRT01EDTM":"2021-02-16 17:45:28","TRT02SDTM":"2021-02-16 17:45:28","TRT02EDTM":"2022-02-16 23:45:28","AP01SDTM":"2020-01-11 03:34:36","AP01EDTM":"2021-02-16 17:45:28","AP02SDTM":"2021-02-16 17:45:28","AP02EDTM":"2022-02-16 23:45:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":768,"DCSREAS":"DEATH","DTHDT":"2022-02-23","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-23","DTHADY":773,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8069,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.98882,"AVALU":"mg/L","BASE2":9.49416,"BASE":10.78759,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.50534,"PCHG2":-15.85539,"CHG":-2.79877,"PCHG":-25.94432,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-1","BTOXGR":"3","ADTM":"2021-05-09 03:34:36","ADY":484,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-272","SUBJID":"id-272","SITEID":"CHN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.17023,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-08","TRTSDTM":"2020-01-11 03:34:36","TRTEDTM":"2022-02-16 23:45:28","TRT01SDTM":"2020-01-11 03:34:36","TRT01EDTM":"2021-02-16 17:45:28","TRT02SDTM":"2021-02-16 17:45:28","TRT02EDTM":"2022-02-16 23:45:28","AP01SDTM":"2020-01-11 03:34:36","AP01EDTM":"2021-02-16 17:45:28","AP02SDTM":"2021-02-16 17:45:28","AP02EDTM":"2022-02-16 23:45:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":768,"DCSREAS":"DEATH","DTHDT":"2022-02-23","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-23","DTHADY":773,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2176,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77672,"AVALU":"g/L","BASE2":2.77672,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-01 03:34:36","ADY":81,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-272","SUBJID":"id-272","SITEID":"CHN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.17023,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-08","TRTSDTM":"2020-01-11 03:34:36","TRTEDTM":"2022-02-16 23:45:28","TRT01SDTM":"2020-01-11 03:34:36","TRT01EDTM":"2021-02-16 17:45:28","TRT02SDTM":"2021-02-16 17:45:28","TRT02EDTM":"2022-02-16 23:45:28","AP01SDTM":"2020-01-11 03:34:36","AP01EDTM":"2021-02-16 17:45:28","AP02SDTM":"2021-02-16 17:45:28","AP02EDTM":"2022-02-16 23:45:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":768,"DCSREAS":"DEATH","DTHDT":"2022-02-23","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-23","DTHADY":773,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6265,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79688,"AVALU":"g/L","BASE2":2.77672,"BASE":2.79688,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.02016,"PCHG2":0.72611,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-07 03:34:36","ADY":87,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-272","SUBJID":"id-272","SITEID":"CHN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.17023,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-08","TRTSDTM":"2020-01-11 03:34:36","TRTEDTM":"2022-02-16 23:45:28","TRT01SDTM":"2020-01-11 03:34:36","TRT01EDTM":"2021-02-16 17:45:28","TRT02SDTM":"2021-02-16 17:45:28","TRT02EDTM":"2022-02-16 23:45:28","AP01SDTM":"2020-01-11 03:34:36","AP01EDTM":"2021-02-16 17:45:28","AP02SDTM":"2021-02-16 17:45:28","AP02EDTM":"2022-02-16 23:45:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":768,"DCSREAS":"DEATH","DTHDT":"2022-02-23","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-23","DTHADY":773,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5179,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.09744,"AVALU":"g/L","BASE2":2.77672,"BASE":2.79688,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.32072,"PCHG2":11.55045,"CHG":0.30056,"PCHG":10.74631,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-08-18 03:34:36","ADY":220,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-272","SUBJID":"id-272","SITEID":"CHN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.17023,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-08","TRTSDTM":"2020-01-11 03:34:36","TRTEDTM":"2022-02-16 23:45:28","TRT01SDTM":"2020-01-11 03:34:36","TRT01EDTM":"2021-02-16 17:45:28","TRT02SDTM":"2021-02-16 17:45:28","TRT02EDTM":"2022-02-16 23:45:28","AP01SDTM":"2020-01-11 03:34:36","AP01EDTM":"2021-02-16 17:45:28","AP02SDTM":"2021-02-16 17:45:28","AP02EDTM":"2022-02-16 23:45:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":768,"DCSREAS":"DEATH","DTHDT":"2022-02-23","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-23","DTHADY":773,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4959,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04362,"AVALU":"g/L","BASE2":2.77672,"BASE":2.79688,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.2669,"PCHG2":9.61202,"CHG":0.24674,"PCHG":8.82185,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-12-08 03:34:36","ADY":332,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-272","SUBJID":"id-272","SITEID":"CHN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.17023,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-08","TRTSDTM":"2020-01-11 03:34:36","TRTEDTM":"2022-02-16 23:45:28","TRT01SDTM":"2020-01-11 03:34:36","TRT01EDTM":"2021-02-16 17:45:28","TRT02SDTM":"2021-02-16 17:45:28","TRT02EDTM":"2022-02-16 23:45:28","AP01SDTM":"2020-01-11 03:34:36","AP01EDTM":"2021-02-16 17:45:28","AP02SDTM":"2021-02-16 17:45:28","AP02EDTM":"2022-02-16 23:45:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":768,"DCSREAS":"DEATH","DTHDT":"2022-02-23","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-23","DTHADY":773,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6909,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98131,"AVALU":"g/L","BASE2":2.77672,"BASE":2.79688,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.20459,"PCHG2":7.36807,"CHG":0.18443,"PCHG":6.59408,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-16 03:34:36","ADY":340,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-272","SUBJID":"id-272","SITEID":"CHN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.17023,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-08","TRTSDTM":"2020-01-11 03:34:36","TRTEDTM":"2022-02-16 23:45:28","TRT01SDTM":"2020-01-11 03:34:36","TRT01EDTM":"2021-02-16 17:45:28","TRT02SDTM":"2021-02-16 17:45:28","TRT02EDTM":"2022-02-16 23:45:28","AP01SDTM":"2020-01-11 03:34:36","AP01EDTM":"2021-02-16 17:45:28","AP02SDTM":"2021-02-16 17:45:28","AP02EDTM":"2022-02-16 23:45:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":768,"DCSREAS":"DEATH","DTHDT":"2022-02-23","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-23","DTHADY":773,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4357,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85333,"AVALU":"g/L","BASE2":2.77672,"BASE":2.79688,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07661,"PCHG2":2.75904,"CHG":0.05645,"PCHG":2.01828,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-12 03:34:36","ADY":398,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-272","SUBJID":"id-272","SITEID":"CHN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":7.17023,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-08","TRTSDTM":"2020-01-11 03:34:36","TRTEDTM":"2022-02-16 23:45:28","TRT01SDTM":"2020-01-11 03:34:36","TRT01EDTM":"2021-02-16 17:45:28","TRT02SDTM":"2021-02-16 17:45:28","TRT02EDTM":"2022-02-16 23:45:28","AP01SDTM":"2020-01-11 03:34:36","AP01EDTM":"2021-02-16 17:45:28","AP02SDTM":"2021-02-16 17:45:28","AP02EDTM":"2022-02-16 23:45:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":768,"DCSREAS":"DEATH","DTHDT":"2022-02-23","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-23","DTHADY":773,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7905,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04756,"AVALU":"g/L","BASE2":2.77672,"BASE":2.79688,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.27084,"PCHG2":9.75409,"CHG":0.25068,"PCHG":8.9629,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-05-09 03:34:36","ADY":484,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-274","SUBJID":"id-274","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.58528,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-14 16:57:27","TRTEDTM":"2022-02-19 21:03:11","TRT01SDTM":"2019-10-14 16:57:27","TRT01EDTM":"2021-02-19 15:03:11","TRT02SDTM":"2021-02-19 15:03:11","TRT02EDTM":"2022-02-19 21:03:11","AP01SDTM":"2019-10-14 16:57:27","AP01EDTM":"2021-02-19 15:03:11","AP02SDTM":"2021-02-19 15:03:11","AP02EDTM":"2022-02-19 21:03:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":860,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":890,"ADTHAUT":"No","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7916,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.43039,"AVALU":"U/L","BASE2":31.43039,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-23 16:57:27","ADY":40,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-274","SUBJID":"id-274","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.58528,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-14 16:57:27","TRTEDTM":"2022-02-19 21:03:11","TRT01SDTM":"2019-10-14 16:57:27","TRT01EDTM":"2021-02-19 15:03:11","TRT02SDTM":"2021-02-19 15:03:11","TRT02EDTM":"2022-02-19 21:03:11","AP01SDTM":"2019-10-14 16:57:27","AP01EDTM":"2021-02-19 15:03:11","AP02SDTM":"2021-02-19 15:03:11","AP02EDTM":"2022-02-19 21:03:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":860,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":890,"ADTHAUT":"No","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":639,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.34723,"AVALU":"U/L","BASE2":31.43039,"BASE":25.34723,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-6.08316,"PCHG2":-19.35438,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-29 16:57:27","ADY":412,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-274","SUBJID":"id-274","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.58528,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-14 16:57:27","TRTEDTM":"2022-02-19 21:03:11","TRT01SDTM":"2019-10-14 16:57:27","TRT01EDTM":"2021-02-19 15:03:11","TRT02SDTM":"2021-02-19 15:03:11","TRT02EDTM":"2022-02-19 21:03:11","AP01SDTM":"2019-10-14 16:57:27","AP01EDTM":"2021-02-19 15:03:11","AP02SDTM":"2021-02-19 15:03:11","AP02EDTM":"2022-02-19 21:03:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":860,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":890,"ADTHAUT":"No","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2145,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.33214,"AVALU":"U/L","BASE2":31.43039,"BASE":25.34723,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-20.09825,"PCHG2":-63.94529,"CHG":-14.0151,"PCHG":-55.29241,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-05 16:57:27","ADY":600,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-274","SUBJID":"id-274","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.58528,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-14 16:57:27","TRTEDTM":"2022-02-19 21:03:11","TRT01SDTM":"2019-10-14 16:57:27","TRT01EDTM":"2021-02-19 15:03:11","TRT02SDTM":"2021-02-19 15:03:11","TRT02EDTM":"2022-02-19 21:03:11","AP01SDTM":"2019-10-14 16:57:27","AP01EDTM":"2021-02-19 15:03:11","AP02SDTM":"2021-02-19 15:03:11","AP02EDTM":"2022-02-19 21:03:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":860,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":890,"ADTHAUT":"No","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4762,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.50683,"AVALU":"U/L","BASE2":31.43039,"BASE":25.34723,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.92356,"PCHG2":-18.84661,"CHG":0.15959,"PCHG":0.62963,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-03 16:57:27","ADY":659,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-274","SUBJID":"id-274","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.58528,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-14 16:57:27","TRTEDTM":"2022-02-19 21:03:11","TRT01SDTM":"2019-10-14 16:57:27","TRT01EDTM":"2021-02-19 15:03:11","TRT02SDTM":"2021-02-19 15:03:11","TRT02EDTM":"2022-02-19 21:03:11","AP01SDTM":"2019-10-14 16:57:27","AP01EDTM":"2021-02-19 15:03:11","AP02SDTM":"2021-02-19 15:03:11","AP02EDTM":"2022-02-19 21:03:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":860,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":890,"ADTHAUT":"No","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6799,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.8147,"AVALU":"U/L","BASE2":31.43039,"BASE":25.34723,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.61569,"PCHG2":-5.14052,"CHG":4.46747,"PCHG":17.62508,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-29 16:57:27","ADY":716,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-274","SUBJID":"id-274","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.58528,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-14 16:57:27","TRTEDTM":"2022-02-19 21:03:11","TRT01SDTM":"2019-10-14 16:57:27","TRT01EDTM":"2021-02-19 15:03:11","TRT02SDTM":"2021-02-19 15:03:11","TRT02EDTM":"2022-02-19 21:03:11","AP01SDTM":"2019-10-14 16:57:27","AP01EDTM":"2021-02-19 15:03:11","AP02SDTM":"2021-02-19 15:03:11","AP02EDTM":"2022-02-19 21:03:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":860,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":890,"ADTHAUT":"No","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7877,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.65538,"AVALU":"U/L","BASE2":31.43039,"BASE":25.34723,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-21.775,"PCHG2":-69.2801,"CHG":-15.69185,"PCHG":-61.90754,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-18 16:57:27","ADY":735,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-274","SUBJID":"id-274","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.58528,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-14 16:57:27","TRTEDTM":"2022-02-19 21:03:11","TRT01SDTM":"2019-10-14 16:57:27","TRT01EDTM":"2021-02-19 15:03:11","TRT02SDTM":"2021-02-19 15:03:11","TRT02EDTM":"2022-02-19 21:03:11","AP01SDTM":"2019-10-14 16:57:27","AP01EDTM":"2021-02-19 15:03:11","AP02SDTM":"2021-02-19 15:03:11","AP02EDTM":"2022-02-19 21:03:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":860,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":890,"ADTHAUT":"No","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2889,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.91122,"AVALU":"U/L","BASE2":31.43039,"BASE":25.34723,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.51917,"PCHG2":-14.37835,"CHG":1.56398,"PCHG":6.17023,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-14 16:57:27","ADY":854,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-274","SUBJID":"id-274","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.58528,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-14 16:57:27","TRTEDTM":"2022-02-19 21:03:11","TRT01SDTM":"2019-10-14 16:57:27","TRT01EDTM":"2021-02-19 15:03:11","TRT02SDTM":"2021-02-19 15:03:11","TRT02EDTM":"2022-02-19 21:03:11","AP01SDTM":"2019-10-14 16:57:27","AP01EDTM":"2021-02-19 15:03:11","AP02SDTM":"2021-02-19 15:03:11","AP02EDTM":"2022-02-19 21:03:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":860,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":890,"ADTHAUT":"No","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2693,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.50983,"AVALU":"mg/L","BASE2":10.50983,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"2","BTOXGR":"0","ADTM":"2019-11-23 16:57:27","ADY":40,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-274","SUBJID":"id-274","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.58528,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-14 16:57:27","TRTEDTM":"2022-02-19 21:03:11","TRT01SDTM":"2019-10-14 16:57:27","TRT01EDTM":"2021-02-19 15:03:11","TRT02SDTM":"2021-02-19 15:03:11","TRT02EDTM":"2022-02-19 21:03:11","AP01SDTM":"2019-10-14 16:57:27","AP01EDTM":"2021-02-19 15:03:11","AP02SDTM":"2021-02-19 15:03:11","AP02EDTM":"2022-02-19 21:03:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":860,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":890,"ADTHAUT":"No","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7427,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.64463,"AVALU":"mg/L","BASE2":10.50983,"BASE":9.64463,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.8652,"PCHG2":-8.23231,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-29 16:57:27","ADY":412,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-274","SUBJID":"id-274","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.58528,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-14 16:57:27","TRTEDTM":"2022-02-19 21:03:11","TRT01SDTM":"2019-10-14 16:57:27","TRT01EDTM":"2021-02-19 15:03:11","TRT02SDTM":"2021-02-19 15:03:11","TRT02EDTM":"2022-02-19 21:03:11","AP01SDTM":"2019-10-14 16:57:27","AP01EDTM":"2021-02-19 15:03:11","AP02SDTM":"2021-02-19 15:03:11","AP02EDTM":"2022-02-19 21:03:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":860,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":890,"ADTHAUT":"No","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3483,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.12726,"AVALU":"mg/L","BASE2":10.50983,"BASE":9.64463,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.38257,"PCHG2":-22.66991,"CHG":-1.51737,"PCHG":-15.73277,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-05 16:57:27","ADY":600,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-274","SUBJID":"id-274","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.58528,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-14 16:57:27","TRTEDTM":"2022-02-19 21:03:11","TRT01SDTM":"2019-10-14 16:57:27","TRT01EDTM":"2021-02-19 15:03:11","TRT02SDTM":"2021-02-19 15:03:11","TRT02EDTM":"2022-02-19 21:03:11","AP01SDTM":"2019-10-14 16:57:27","AP01EDTM":"2021-02-19 15:03:11","AP02SDTM":"2021-02-19 15:03:11","AP02EDTM":"2022-02-19 21:03:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":860,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":890,"ADTHAUT":"No","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1702,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.21284,"AVALU":"mg/L","BASE2":10.50983,"BASE":9.64463,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.29699,"PCHG2":-21.85561,"CHG":-1.43179,"PCHG":-14.84542,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-03 16:57:27","ADY":659,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-274","SUBJID":"id-274","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.58528,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-14 16:57:27","TRTEDTM":"2022-02-19 21:03:11","TRT01SDTM":"2019-10-14 16:57:27","TRT01EDTM":"2021-02-19 15:03:11","TRT02SDTM":"2021-02-19 15:03:11","TRT02EDTM":"2022-02-19 21:03:11","AP01SDTM":"2019-10-14 16:57:27","AP01EDTM":"2021-02-19 15:03:11","AP02SDTM":"2021-02-19 15:03:11","AP02EDTM":"2022-02-19 21:03:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":860,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":890,"ADTHAUT":"No","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":137,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.8132,"AVALU":"mg/L","BASE2":10.50983,"BASE":9.64463,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.69663,"PCHG2":-16.14327,"CHG":-0.83143,"PCHG":-8.62064,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-29 16:57:27","ADY":716,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-274","SUBJID":"id-274","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.58528,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-14 16:57:27","TRTEDTM":"2022-02-19 21:03:11","TRT01SDTM":"2019-10-14 16:57:27","TRT01EDTM":"2021-02-19 15:03:11","TRT02SDTM":"2021-02-19 15:03:11","TRT02EDTM":"2022-02-19 21:03:11","AP01SDTM":"2019-10-14 16:57:27","AP01EDTM":"2021-02-19 15:03:11","AP02SDTM":"2021-02-19 15:03:11","AP02EDTM":"2022-02-19 21:03:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":860,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":890,"ADTHAUT":"No","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4241,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.21625,"AVALU":"mg/L","BASE2":10.50983,"BASE":9.64463,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.29359,"PCHG2":-12.30834,"CHG":-0.42838,"PCHG":-4.44168,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-18 16:57:27","ADY":735,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-274","SUBJID":"id-274","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.58528,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-14 16:57:27","TRTEDTM":"2022-02-19 21:03:11","TRT01SDTM":"2019-10-14 16:57:27","TRT01EDTM":"2021-02-19 15:03:11","TRT02SDTM":"2021-02-19 15:03:11","TRT02EDTM":"2022-02-19 21:03:11","AP01SDTM":"2019-10-14 16:57:27","AP01EDTM":"2021-02-19 15:03:11","AP02SDTM":"2021-02-19 15:03:11","AP02EDTM":"2022-02-19 21:03:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":860,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":890,"ADTHAUT":"No","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":348,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.25752,"AVALU":"mg/L","BASE2":10.50983,"BASE":9.64463,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.25231,"PCHG2":-30.94541,"CHG":-2.38711,"PCHG":-24.75065,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-02-14 16:57:27","ADY":854,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-274","SUBJID":"id-274","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.58528,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-14 16:57:27","TRTEDTM":"2022-02-19 21:03:11","TRT01SDTM":"2019-10-14 16:57:27","TRT01EDTM":"2021-02-19 15:03:11","TRT02SDTM":"2021-02-19 15:03:11","TRT02EDTM":"2022-02-19 21:03:11","AP01SDTM":"2019-10-14 16:57:27","AP01EDTM":"2021-02-19 15:03:11","AP02SDTM":"2021-02-19 15:03:11","AP02EDTM":"2022-02-19 21:03:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":860,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":890,"ADTHAUT":"No","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1156,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.67815,"AVALU":"g/L","BASE2":2.67815,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-23 16:57:27","ADY":40,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-274","SUBJID":"id-274","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.58528,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-14 16:57:27","TRTEDTM":"2022-02-19 21:03:11","TRT01SDTM":"2019-10-14 16:57:27","TRT01EDTM":"2021-02-19 15:03:11","TRT02SDTM":"2021-02-19 15:03:11","TRT02EDTM":"2022-02-19 21:03:11","AP01SDTM":"2019-10-14 16:57:27","AP01EDTM":"2021-02-19 15:03:11","AP02SDTM":"2021-02-19 15:03:11","AP02EDTM":"2022-02-19 21:03:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":860,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":890,"ADTHAUT":"No","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2008,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86968,"AVALU":"g/L","BASE2":2.67815,"BASE":2.86968,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.19152,"PCHG2":7.15128,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-29 16:57:27","ADY":412,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-274","SUBJID":"id-274","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.58528,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-14 16:57:27","TRTEDTM":"2022-02-19 21:03:11","TRT01SDTM":"2019-10-14 16:57:27","TRT01EDTM":"2021-02-19 15:03:11","TRT02SDTM":"2021-02-19 15:03:11","TRT02EDTM":"2022-02-19 21:03:11","AP01SDTM":"2019-10-14 16:57:27","AP01EDTM":"2021-02-19 15:03:11","AP02SDTM":"2021-02-19 15:03:11","AP02EDTM":"2022-02-19 21:03:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":860,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":890,"ADTHAUT":"No","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":85,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81873,"AVALU":"g/L","BASE2":2.67815,"BASE":2.86968,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14057,"PCHG2":5.24893,"CHG":-0.05095,"PCHG":-1.77539,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-05 16:57:27","ADY":600,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-274","SUBJID":"id-274","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.58528,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-14 16:57:27","TRTEDTM":"2022-02-19 21:03:11","TRT01SDTM":"2019-10-14 16:57:27","TRT01EDTM":"2021-02-19 15:03:11","TRT02SDTM":"2021-02-19 15:03:11","TRT02EDTM":"2022-02-19 21:03:11","AP01SDTM":"2019-10-14 16:57:27","AP01EDTM":"2021-02-19 15:03:11","AP02SDTM":"2021-02-19 15:03:11","AP02EDTM":"2022-02-19 21:03:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":860,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":890,"ADTHAUT":"No","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1953,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98213,"AVALU":"g/L","BASE2":2.67815,"BASE":2.86968,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.30397,"PCHG2":11.35015,"CHG":0.11245,"PCHG":3.91864,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-03 16:57:27","ADY":659,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-274","SUBJID":"id-274","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.58528,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-14 16:57:27","TRTEDTM":"2022-02-19 21:03:11","TRT01SDTM":"2019-10-14 16:57:27","TRT01EDTM":"2021-02-19 15:03:11","TRT02SDTM":"2021-02-19 15:03:11","TRT02EDTM":"2022-02-19 21:03:11","AP01SDTM":"2019-10-14 16:57:27","AP01EDTM":"2021-02-19 15:03:11","AP02SDTM":"2021-02-19 15:03:11","AP02EDTM":"2022-02-19 21:03:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":860,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":890,"ADTHAUT":"No","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1134,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94435,"AVALU":"g/L","BASE2":2.67815,"BASE":2.86968,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.26619,"PCHG2":9.93944,"CHG":0.07467,"PCHG":2.60208,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-29 16:57:27","ADY":716,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-274","SUBJID":"id-274","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.58528,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-14 16:57:27","TRTEDTM":"2022-02-19 21:03:11","TRT01SDTM":"2019-10-14 16:57:27","TRT01EDTM":"2021-02-19 15:03:11","TRT02SDTM":"2021-02-19 15:03:11","TRT02EDTM":"2022-02-19 21:03:11","AP01SDTM":"2019-10-14 16:57:27","AP01EDTM":"2021-02-19 15:03:11","AP02SDTM":"2021-02-19 15:03:11","AP02EDTM":"2022-02-19 21:03:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":860,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":890,"ADTHAUT":"No","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7958,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92647,"AVALU":"g/L","BASE2":2.67815,"BASE":2.86968,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.24832,"PCHG2":9.27199,"CHG":0.0568,"PCHG":1.97918,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-18 16:57:27","ADY":735,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-274","SUBJID":"id-274","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.58528,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-10","TRTSDTM":"2019-10-14 16:57:27","TRTEDTM":"2022-02-19 21:03:11","TRT01SDTM":"2019-10-14 16:57:27","TRT01EDTM":"2021-02-19 15:03:11","TRT02SDTM":"2021-02-19 15:03:11","TRT02EDTM":"2022-02-19 21:03:11","AP01SDTM":"2019-10-14 16:57:27","AP01EDTM":"2021-02-19 15:03:11","AP02SDTM":"2021-02-19 15:03:11","AP02EDTM":"2022-02-19 21:03:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":860,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"SUICIDE","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":890,"ADTHAUT":"No","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4527,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88571,"AVALU":"g/L","BASE2":2.67815,"BASE":2.86968,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.20755,"PCHG2":7.74978,"CHG":0.01603,"PCHG":0.55856,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-14 16:57:27","ADY":854,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-284","SUBJID":"id-284","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":8.02225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-13 23:33:11","TRTEDTM":"2023-09-14 17:33:11","TRT01SDTM":"2020-09-13 23:33:11","TRT01EDTM":"2022-09-14 11:33:11","TRT02SDTM":"2022-09-14 11:33:11","TRT02EDTM":"2023-09-14 17:33:11","AP01SDTM":"2020-09-13 23:33:11","AP01EDTM":"2022-09-14 11:33:11","AP02SDTM":"2022-09-14 11:33:11","AP02EDTM":"2023-09-14 17:33:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-14","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6180,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.44218,"AVALU":"U/L","BASE2":11.44218,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-20 23:33:11","ADY":7,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-284","SUBJID":"id-284","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":8.02225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-13 23:33:11","TRTEDTM":"2023-09-14 17:33:11","TRT01SDTM":"2020-09-13 23:33:11","TRT01EDTM":"2022-09-14 11:33:11","TRT02SDTM":"2022-09-14 11:33:11","TRT02EDTM":"2023-09-14 17:33:11","AP01SDTM":"2020-09-13 23:33:11","AP01EDTM":"2022-09-14 11:33:11","AP02SDTM":"2022-09-14 11:33:11","AP02EDTM":"2023-09-14 17:33:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-14","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8287,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.04477,"AVALU":"U/L","BASE2":11.44218,"BASE":20.04477,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":8.60259,"PCHG2":75.18314,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-28 23:33:11","ADY":257,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-284","SUBJID":"id-284","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":8.02225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-13 23:33:11","TRTEDTM":"2023-09-14 17:33:11","TRT01SDTM":"2020-09-13 23:33:11","TRT01EDTM":"2022-09-14 11:33:11","TRT02SDTM":"2022-09-14 11:33:11","TRT02EDTM":"2023-09-14 17:33:11","AP01SDTM":"2020-09-13 23:33:11","AP01EDTM":"2022-09-14 11:33:11","AP02SDTM":"2022-09-14 11:33:11","AP02EDTM":"2023-09-14 17:33:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-14","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":274,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.72465,"AVALU":"U/L","BASE2":11.44218,"BASE":20.04477,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":22.28247,"PCHG2":194.7397,"CHG":13.67988,"PCHG":68.24661,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-20 23:33:11","ADY":372,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-284","SUBJID":"id-284","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":8.02225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-13 23:33:11","TRTEDTM":"2023-09-14 17:33:11","TRT01SDTM":"2020-09-13 23:33:11","TRT01EDTM":"2022-09-14 11:33:11","TRT02SDTM":"2022-09-14 11:33:11","TRT02EDTM":"2023-09-14 17:33:11","AP01SDTM":"2020-09-13 23:33:11","AP01EDTM":"2022-09-14 11:33:11","AP02SDTM":"2022-09-14 11:33:11","AP02EDTM":"2023-09-14 17:33:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-14","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6872,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.24962,"AVALU":"U/L","BASE2":11.44218,"BASE":20.04477,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.80744,"PCHG2":59.49426,"CHG":-1.79515,"PCHG":-8.9557,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-10 23:33:11","ADY":392,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-284","SUBJID":"id-284","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":8.02225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-13 23:33:11","TRTEDTM":"2023-09-14 17:33:11","TRT01SDTM":"2020-09-13 23:33:11","TRT01EDTM":"2022-09-14 11:33:11","TRT02SDTM":"2022-09-14 11:33:11","TRT02EDTM":"2023-09-14 17:33:11","AP01SDTM":"2020-09-13 23:33:11","AP01EDTM":"2022-09-14 11:33:11","AP02SDTM":"2022-09-14 11:33:11","AP02EDTM":"2023-09-14 17:33:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-14","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6063,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.73313,"AVALU":"U/L","BASE2":11.44218,"BASE":20.04477,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.29095,"PCHG2":46.24076,"CHG":-3.31164,"PCHG":-16.52121,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-13 23:33:11","ADY":546,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-284","SUBJID":"id-284","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":8.02225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-13 23:33:11","TRTEDTM":"2023-09-14 17:33:11","TRT01SDTM":"2020-09-13 23:33:11","TRT01EDTM":"2022-09-14 11:33:11","TRT02SDTM":"2022-09-14 11:33:11","TRT02EDTM":"2023-09-14 17:33:11","AP01SDTM":"2020-09-13 23:33:11","AP01EDTM":"2022-09-14 11:33:11","AP02SDTM":"2022-09-14 11:33:11","AP02EDTM":"2023-09-14 17:33:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-14","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2861,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.34063,"AVALU":"U/L","BASE2":11.44218,"BASE":20.04477,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.89845,"PCHG2":51.55006,"CHG":-2.70414,"PCHG":-13.4905,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-14 23:33:11","ADY":639,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-284","SUBJID":"id-284","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":8.02225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-13 23:33:11","TRTEDTM":"2023-09-14 17:33:11","TRT01SDTM":"2020-09-13 23:33:11","TRT01EDTM":"2022-09-14 11:33:11","TRT02SDTM":"2022-09-14 11:33:11","TRT02EDTM":"2023-09-14 17:33:11","AP01SDTM":"2020-09-13 23:33:11","AP01EDTM":"2022-09-14 11:33:11","AP02SDTM":"2022-09-14 11:33:11","AP02EDTM":"2023-09-14 17:33:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-14","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6716,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.6117,"AVALU":"U/L","BASE2":11.44218,"BASE":20.04477,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.83048,"PCHG2":-24.73724,"CHG":-11.43307,"PCHG":-57.03767,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-25 23:33:11","ADY":711,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-284","SUBJID":"id-284","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":8.02225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-13 23:33:11","TRTEDTM":"2023-09-14 17:33:11","TRT01SDTM":"2020-09-13 23:33:11","TRT01EDTM":"2022-09-14 11:33:11","TRT02SDTM":"2022-09-14 11:33:11","TRT02EDTM":"2023-09-14 17:33:11","AP01SDTM":"2020-09-13 23:33:11","AP01EDTM":"2022-09-14 11:33:11","AP02SDTM":"2022-09-14 11:33:11","AP02EDTM":"2023-09-14 17:33:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-14","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":918,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.40831,"AVALU":"mg/L","BASE2":10.40831,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"","ATOXGR":"2","BTOXGR":"-3","ADTM":"2020-09-20 23:33:11","ADY":7,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-284","SUBJID":"id-284","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":8.02225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-13 23:33:11","TRTEDTM":"2023-09-14 17:33:11","TRT01SDTM":"2020-09-13 23:33:11","TRT01EDTM":"2022-09-14 11:33:11","TRT02SDTM":"2022-09-14 11:33:11","TRT02EDTM":"2023-09-14 17:33:11","AP01SDTM":"2020-09-13 23:33:11","AP01EDTM":"2022-09-14 11:33:11","AP02SDTM":"2022-09-14 11:33:11","AP02EDTM":"2023-09-14 17:33:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-14","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7361,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.7885,"AVALU":"mg/L","BASE2":10.40831,"BASE":7.7885,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.61981,"PCHG2":-25.17038,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2021-05-28 23:33:11","ADY":257,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-284","SUBJID":"id-284","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":8.02225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-13 23:33:11","TRTEDTM":"2023-09-14 17:33:11","TRT01SDTM":"2020-09-13 23:33:11","TRT01EDTM":"2022-09-14 11:33:11","TRT02SDTM":"2022-09-14 11:33:11","TRT02EDTM":"2023-09-14 17:33:11","AP01SDTM":"2020-09-13 23:33:11","AP01EDTM":"2022-09-14 11:33:11","AP02SDTM":"2022-09-14 11:33:11","AP02EDTM":"2023-09-14 17:33:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-14","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1511,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.28073,"AVALU":"mg/L","BASE2":10.40831,"BASE":7.7885,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.12758,"PCHG2":-10.83348,"CHG":1.49223,"PCHG":19.15939,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-09-20 23:33:11","ADY":372,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-284","SUBJID":"id-284","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":8.02225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-13 23:33:11","TRTEDTM":"2023-09-14 17:33:11","TRT01SDTM":"2020-09-13 23:33:11","TRT01EDTM":"2022-09-14 11:33:11","TRT02SDTM":"2022-09-14 11:33:11","TRT02EDTM":"2023-09-14 17:33:11","AP01SDTM":"2020-09-13 23:33:11","AP01EDTM":"2022-09-14 11:33:11","AP02SDTM":"2022-09-14 11:33:11","AP02EDTM":"2023-09-14 17:33:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-14","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5099,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.8734,"AVALU":"mg/L","BASE2":10.40831,"BASE":7.7885,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.5349,"PCHG2":-14.74691,"CHG":1.08491,"PCHG":13.9296,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-10-10 23:33:11","ADY":392,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-284","SUBJID":"id-284","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":8.02225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-13 23:33:11","TRTEDTM":"2023-09-14 17:33:11","TRT01SDTM":"2020-09-13 23:33:11","TRT01EDTM":"2022-09-14 11:33:11","TRT02SDTM":"2022-09-14 11:33:11","TRT02EDTM":"2023-09-14 17:33:11","AP01SDTM":"2020-09-13 23:33:11","AP01EDTM":"2022-09-14 11:33:11","AP02SDTM":"2022-09-14 11:33:11","AP02EDTM":"2023-09-14 17:33:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-14","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1620,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.02561,"AVALU":"mg/L","BASE2":10.40831,"BASE":7.7885,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.3827,"PCHG2":-22.89225,"CHG":0.23711,"PCHG":3.04442,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2022-03-13 23:33:11","ADY":546,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-284","SUBJID":"id-284","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":8.02225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-13 23:33:11","TRTEDTM":"2023-09-14 17:33:11","TRT01SDTM":"2020-09-13 23:33:11","TRT01EDTM":"2022-09-14 11:33:11","TRT02SDTM":"2022-09-14 11:33:11","TRT02EDTM":"2023-09-14 17:33:11","AP01SDTM":"2020-09-13 23:33:11","AP01EDTM":"2022-09-14 11:33:11","AP02SDTM":"2022-09-14 11:33:11","AP02EDTM":"2023-09-14 17:33:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-14","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3905,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.05147,"AVALU":"mg/L","BASE2":10.40831,"BASE":7.7885,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.35683,"PCHG2":-13.03605,"CHG":1.26298,"PCHG":16.21594,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2022-06-14 23:33:11","ADY":639,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-284","SUBJID":"id-284","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":8.02225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-13 23:33:11","TRTEDTM":"2023-09-14 17:33:11","TRT01SDTM":"2020-09-13 23:33:11","TRT01EDTM":"2022-09-14 11:33:11","TRT02SDTM":"2022-09-14 11:33:11","TRT02EDTM":"2023-09-14 17:33:11","AP01SDTM":"2020-09-13 23:33:11","AP01EDTM":"2022-09-14 11:33:11","AP02SDTM":"2022-09-14 11:33:11","AP02EDTM":"2023-09-14 17:33:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-14","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":928,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.40011,"AVALU":"mg/L","BASE2":10.40831,"BASE":7.7885,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.00819,"PCHG2":-9.68644,"CHG":1.61162,"PCHG":20.69226,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2022-08-25 23:33:11","ADY":711,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-284","SUBJID":"id-284","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":8.02225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-13 23:33:11","TRTEDTM":"2023-09-14 17:33:11","TRT01SDTM":"2020-09-13 23:33:11","TRT01EDTM":"2022-09-14 11:33:11","TRT02SDTM":"2022-09-14 11:33:11","TRT02EDTM":"2023-09-14 17:33:11","AP01SDTM":"2020-09-13 23:33:11","AP01EDTM":"2022-09-14 11:33:11","AP02SDTM":"2022-09-14 11:33:11","AP02EDTM":"2023-09-14 17:33:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-14","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1379,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8116,"AVALU":"g/L","BASE2":2.8116,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-20 23:33:11","ADY":7,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-284","SUBJID":"id-284","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":8.02225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-13 23:33:11","TRTEDTM":"2023-09-14 17:33:11","TRT01SDTM":"2020-09-13 23:33:11","TRT01EDTM":"2022-09-14 11:33:11","TRT02SDTM":"2022-09-14 11:33:11","TRT02EDTM":"2023-09-14 17:33:11","AP01SDTM":"2020-09-13 23:33:11","AP01EDTM":"2022-09-14 11:33:11","AP02SDTM":"2022-09-14 11:33:11","AP02EDTM":"2023-09-14 17:33:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-14","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":596,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80071,"AVALU":"g/L","BASE2":2.8116,"BASE":2.80071,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.01089,"PCHG2":-0.38715,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-28 23:33:11","ADY":257,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-284","SUBJID":"id-284","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":8.02225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-13 23:33:11","TRTEDTM":"2023-09-14 17:33:11","TRT01SDTM":"2020-09-13 23:33:11","TRT01EDTM":"2022-09-14 11:33:11","TRT02SDTM":"2022-09-14 11:33:11","TRT02EDTM":"2023-09-14 17:33:11","AP01SDTM":"2020-09-13 23:33:11","AP01EDTM":"2022-09-14 11:33:11","AP02SDTM":"2022-09-14 11:33:11","AP02EDTM":"2023-09-14 17:33:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-14","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6662,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.73808,"AVALU":"g/L","BASE2":2.8116,"BASE":2.80071,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07352,"PCHG2":-2.61481,"CHG":-0.06263,"PCHG":-2.23631,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-20 23:33:11","ADY":372,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-284","SUBJID":"id-284","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":8.02225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-13 23:33:11","TRTEDTM":"2023-09-14 17:33:11","TRT01SDTM":"2020-09-13 23:33:11","TRT01EDTM":"2022-09-14 11:33:11","TRT02SDTM":"2022-09-14 11:33:11","TRT02EDTM":"2023-09-14 17:33:11","AP01SDTM":"2020-09-13 23:33:11","AP01EDTM":"2022-09-14 11:33:11","AP02SDTM":"2022-09-14 11:33:11","AP02EDTM":"2023-09-14 17:33:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-14","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2044,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94222,"AVALU":"g/L","BASE2":2.8116,"BASE":2.80071,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13063,"PCHG2":4.64596,"CHG":0.14151,"PCHG":5.05268,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-10 23:33:11","ADY":392,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-284","SUBJID":"id-284","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":8.02225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-13 23:33:11","TRTEDTM":"2023-09-14 17:33:11","TRT01SDTM":"2020-09-13 23:33:11","TRT01EDTM":"2022-09-14 11:33:11","TRT02SDTM":"2022-09-14 11:33:11","TRT02EDTM":"2023-09-14 17:33:11","AP01SDTM":"2020-09-13 23:33:11","AP01EDTM":"2022-09-14 11:33:11","AP02SDTM":"2022-09-14 11:33:11","AP02EDTM":"2023-09-14 17:33:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-14","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8390,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.867,"AVALU":"g/L","BASE2":2.8116,"BASE":2.80071,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0554,"PCHG2":1.97048,"CHG":0.06629,"PCHG":2.36679,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-13 23:33:11","ADY":546,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-284","SUBJID":"id-284","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":8.02225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-13 23:33:11","TRTEDTM":"2023-09-14 17:33:11","TRT01SDTM":"2020-09-13 23:33:11","TRT01EDTM":"2022-09-14 11:33:11","TRT02SDTM":"2022-09-14 11:33:11","TRT02EDTM":"2023-09-14 17:33:11","AP01SDTM":"2020-09-13 23:33:11","AP01EDTM":"2022-09-14 11:33:11","AP02SDTM":"2022-09-14 11:33:11","AP02EDTM":"2023-09-14 17:33:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-14","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5135,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89162,"AVALU":"g/L","BASE2":2.8116,"BASE":2.80071,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08003,"PCHG2":2.84632,"CHG":0.09091,"PCHG":3.24604,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-14 23:33:11","ADY":639,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-284","SUBJID":"id-284","SITEID":"CHN-2","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":8.02225,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-13 23:33:11","TRTEDTM":"2023-09-14 17:33:11","TRT01SDTM":"2020-09-13 23:33:11","TRT01EDTM":"2022-09-14 11:33:11","TRT02SDTM":"2022-09-14 11:33:11","TRT02EDTM":"2023-09-14 17:33:11","AP01SDTM":"2020-09-13 23:33:11","AP01EDTM":"2022-09-14 11:33:11","AP02SDTM":"2022-09-14 11:33:11","AP02EDTM":"2023-09-14 17:33:11","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-14","EOSDY":1096,"LSTALVDT":"2023-10-08","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3758,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84381,"AVALU":"g/L","BASE2":2.8116,"BASE":2.80071,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03222,"PCHG2":1.14581,"CHG":0.0431,"PCHG":1.53892,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-25 23:33:11","ADY":711,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-286","SUBJID":"id-286","SITEID":"CHN-2","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.63472,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-16 15:23:23","TRTEDTM":"2022-05-16 09:23:23","TRT01SDTM":"2019-05-16 15:23:23","TRT01EDTM":"2021-05-16 03:23:23","TRT02SDTM":"2021-05-16 03:23:23","TRT02EDTM":"2022-05-16 09:23:23","AP01SDTM":"2019-05-16 15:23:23","AP01EDTM":"2021-05-16 03:23:23","AP02SDTM":"2021-05-16 03:23:23","AP02EDTM":"2022-05-16 09:23:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-16","EOSDY":1096,"LSTALVDT":"2022-05-31","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1957,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.96963,"AVALU":"U/L","BASE2":24.96963,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-3","ADTM":"2019-07-02 15:23:23","ADY":47,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-286","SUBJID":"id-286","SITEID":"CHN-2","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.63472,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-16 15:23:23","TRTEDTM":"2022-05-16 09:23:23","TRT01SDTM":"2019-05-16 15:23:23","TRT01EDTM":"2021-05-16 03:23:23","TRT02SDTM":"2021-05-16 03:23:23","TRT02EDTM":"2022-05-16 09:23:23","AP01SDTM":"2019-05-16 15:23:23","AP01EDTM":"2021-05-16 03:23:23","AP02SDTM":"2021-05-16 03:23:23","AP02EDTM":"2022-05-16 09:23:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-16","EOSDY":1096,"LSTALVDT":"2022-05-31","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3843,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.38228,"AVALU":"U/L","BASE2":24.96963,"BASE":3.38228,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-21.58735,"PCHG2":-86.45441,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2019-09-09 15:23:23","ADY":116,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-286","SUBJID":"id-286","SITEID":"CHN-2","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.63472,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-16 15:23:23","TRTEDTM":"2022-05-16 09:23:23","TRT01SDTM":"2019-05-16 15:23:23","TRT01EDTM":"2021-05-16 03:23:23","TRT02SDTM":"2021-05-16 03:23:23","TRT02EDTM":"2022-05-16 09:23:23","AP01SDTM":"2019-05-16 15:23:23","AP01EDTM":"2021-05-16 03:23:23","AP02SDTM":"2021-05-16 03:23:23","AP02EDTM":"2022-05-16 09:23:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-16","EOSDY":1096,"LSTALVDT":"2022-05-31","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2626,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.18577,"AVALU":"U/L","BASE2":24.96963,"BASE":3.38228,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.78386,"PCHG2":-27.16846,"CHG":14.80349,"PCHG":437.67733,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2020-09-06 15:23:23","ADY":479,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-286","SUBJID":"id-286","SITEID":"CHN-2","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.63472,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-16 15:23:23","TRTEDTM":"2022-05-16 09:23:23","TRT01SDTM":"2019-05-16 15:23:23","TRT01EDTM":"2021-05-16 03:23:23","TRT02SDTM":"2021-05-16 03:23:23","TRT02EDTM":"2022-05-16 09:23:23","AP01SDTM":"2019-05-16 15:23:23","AP01EDTM":"2021-05-16 03:23:23","AP02SDTM":"2021-05-16 03:23:23","AP02EDTM":"2022-05-16 09:23:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-16","EOSDY":1096,"LSTALVDT":"2022-05-31","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4039,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.25738,"AVALU":"U/L","BASE2":24.96963,"BASE":3.38228,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.71226,"PCHG2":-6.85736,"CHG":19.87509,"PCHG":587.62356,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-02-02 15:23:23","ADY":628,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-286","SUBJID":"id-286","SITEID":"CHN-2","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.63472,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-16 15:23:23","TRTEDTM":"2022-05-16 09:23:23","TRT01SDTM":"2019-05-16 15:23:23","TRT01EDTM":"2021-05-16 03:23:23","TRT02SDTM":"2021-05-16 03:23:23","TRT02EDTM":"2022-05-16 09:23:23","AP01SDTM":"2019-05-16 15:23:23","AP01EDTM":"2021-05-16 03:23:23","AP02SDTM":"2021-05-16 03:23:23","AP02EDTM":"2022-05-16 09:23:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-16","EOSDY":1096,"LSTALVDT":"2022-05-31","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":77,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.77669,"AVALU":"U/L","BASE2":24.96963,"BASE":3.38228,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-23.19294,"PCHG2":-92.88458,"CHG":-1.60559,"PCHG":-47.47057,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2021-02-19 15:23:23","ADY":645,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-286","SUBJID":"id-286","SITEID":"CHN-2","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.63472,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-16 15:23:23","TRTEDTM":"2022-05-16 09:23:23","TRT01SDTM":"2019-05-16 15:23:23","TRT01EDTM":"2021-05-16 03:23:23","TRT02SDTM":"2021-05-16 03:23:23","TRT02EDTM":"2022-05-16 09:23:23","AP01SDTM":"2019-05-16 15:23:23","AP01EDTM":"2021-05-16 03:23:23","AP02SDTM":"2021-05-16 03:23:23","AP02EDTM":"2022-05-16 09:23:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-16","EOSDY":1096,"LSTALVDT":"2022-05-31","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4901,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.61925,"AVALU":"U/L","BASE2":24.96963,"BASE":3.38228,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.35038,"PCHG2":-57.47134,"CHG":7.23697,"PCHG":213.96691,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-03-14 15:23:23","ADY":668,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-286","SUBJID":"id-286","SITEID":"CHN-2","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.63472,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-16 15:23:23","TRTEDTM":"2022-05-16 09:23:23","TRT01SDTM":"2019-05-16 15:23:23","TRT01EDTM":"2021-05-16 03:23:23","TRT02SDTM":"2021-05-16 03:23:23","TRT02EDTM":"2022-05-16 09:23:23","AP01SDTM":"2019-05-16 15:23:23","AP01EDTM":"2021-05-16 03:23:23","AP02SDTM":"2021-05-16 03:23:23","AP02EDTM":"2022-05-16 09:23:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-16","EOSDY":1096,"LSTALVDT":"2022-05-31","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2710,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.62449,"AVALU":"U/L","BASE2":24.96963,"BASE":3.38228,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.34515,"PCHG2":-17.40172,"CHG":17.2422,"PCHG":509.78005,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-03-17 15:23:23","ADY":671,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-286","SUBJID":"id-286","SITEID":"CHN-2","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.63472,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-16 15:23:23","TRTEDTM":"2022-05-16 09:23:23","TRT01SDTM":"2019-05-16 15:23:23","TRT01EDTM":"2021-05-16 03:23:23","TRT02SDTM":"2021-05-16 03:23:23","TRT02EDTM":"2022-05-16 09:23:23","AP01SDTM":"2019-05-16 15:23:23","AP01EDTM":"2021-05-16 03:23:23","AP02SDTM":"2021-05-16 03:23:23","AP02EDTM":"2022-05-16 09:23:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-16","EOSDY":1096,"LSTALVDT":"2022-05-31","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2454,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.02657,"AVALU":"mg/L","BASE2":9.02657,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-02 15:23:23","ADY":47,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-286","SUBJID":"id-286","SITEID":"CHN-2","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.63472,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-16 15:23:23","TRTEDTM":"2022-05-16 09:23:23","TRT01SDTM":"2019-05-16 15:23:23","TRT01EDTM":"2021-05-16 03:23:23","TRT02SDTM":"2021-05-16 03:23:23","TRT02EDTM":"2022-05-16 09:23:23","AP01SDTM":"2019-05-16 15:23:23","AP01EDTM":"2021-05-16 03:23:23","AP02SDTM":"2021-05-16 03:23:23","AP02EDTM":"2022-05-16 09:23:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-16","EOSDY":1096,"LSTALVDT":"2022-05-31","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5861,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.31411,"AVALU":"mg/L","BASE2":9.02657,"BASE":9.31411,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.28754,"PCHG2":3.18549,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-09 15:23:23","ADY":116,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-286","SUBJID":"id-286","SITEID":"CHN-2","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.63472,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-16 15:23:23","TRTEDTM":"2022-05-16 09:23:23","TRT01SDTM":"2019-05-16 15:23:23","TRT01EDTM":"2021-05-16 03:23:23","TRT02SDTM":"2021-05-16 03:23:23","TRT02EDTM":"2022-05-16 09:23:23","AP01SDTM":"2019-05-16 15:23:23","AP01EDTM":"2021-05-16 03:23:23","AP02SDTM":"2021-05-16 03:23:23","AP02EDTM":"2022-05-16 09:23:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-16","EOSDY":1096,"LSTALVDT":"2022-05-31","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5390,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.13386,"AVALU":"mg/L","BASE2":9.02657,"BASE":9.31411,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1073,"PCHG2":1.18868,"CHG":-0.18024,"PCHG":-1.93517,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-06 15:23:23","ADY":479,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-286","SUBJID":"id-286","SITEID":"CHN-2","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.63472,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-16 15:23:23","TRTEDTM":"2022-05-16 09:23:23","TRT01SDTM":"2019-05-16 15:23:23","TRT01EDTM":"2021-05-16 03:23:23","TRT02SDTM":"2021-05-16 03:23:23","TRT02EDTM":"2022-05-16 09:23:23","AP01SDTM":"2019-05-16 15:23:23","AP01EDTM":"2021-05-16 03:23:23","AP02SDTM":"2021-05-16 03:23:23","AP02EDTM":"2022-05-16 09:23:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-16","EOSDY":1096,"LSTALVDT":"2022-05-31","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":871,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.19687,"AVALU":"mg/L","BASE2":9.02657,"BASE":9.31411,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.8297,"PCHG2":-20.27014,"CHG":-2.11724,"PCHG":-22.73153,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-02-02 15:23:23","ADY":628,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-286","SUBJID":"id-286","SITEID":"CHN-2","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.63472,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-16 15:23:23","TRTEDTM":"2022-05-16 09:23:23","TRT01SDTM":"2019-05-16 15:23:23","TRT01EDTM":"2021-05-16 03:23:23","TRT02SDTM":"2021-05-16 03:23:23","TRT02EDTM":"2022-05-16 09:23:23","AP01SDTM":"2019-05-16 15:23:23","AP01EDTM":"2021-05-16 03:23:23","AP02SDTM":"2021-05-16 03:23:23","AP02EDTM":"2022-05-16 09:23:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-16","EOSDY":1096,"LSTALVDT":"2022-05-31","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4235,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.06645,"AVALU":"mg/L","BASE2":9.02657,"BASE":9.31411,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.03988,"PCHG2":11.52019,"CHG":0.75234,"PCHG":8.07739,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-02-19 15:23:23","ADY":645,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-286","SUBJID":"id-286","SITEID":"CHN-2","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.63472,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-16 15:23:23","TRTEDTM":"2022-05-16 09:23:23","TRT01SDTM":"2019-05-16 15:23:23","TRT01EDTM":"2021-05-16 03:23:23","TRT02SDTM":"2021-05-16 03:23:23","TRT02EDTM":"2022-05-16 09:23:23","AP01SDTM":"2019-05-16 15:23:23","AP01EDTM":"2021-05-16 03:23:23","AP02SDTM":"2021-05-16 03:23:23","AP02EDTM":"2022-05-16 09:23:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-16","EOSDY":1096,"LSTALVDT":"2022-05-31","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5999,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.2684,"AVALU":"mg/L","BASE2":9.02657,"BASE":9.31411,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.24183,"PCHG2":2.67913,"CHG":-0.04571,"PCHG":-0.49073,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-14 15:23:23","ADY":668,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-286","SUBJID":"id-286","SITEID":"CHN-2","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.63472,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-16 15:23:23","TRTEDTM":"2022-05-16 09:23:23","TRT01SDTM":"2019-05-16 15:23:23","TRT01EDTM":"2021-05-16 03:23:23","TRT02SDTM":"2021-05-16 03:23:23","TRT02EDTM":"2022-05-16 09:23:23","AP01SDTM":"2019-05-16 15:23:23","AP01EDTM":"2021-05-16 03:23:23","AP02SDTM":"2021-05-16 03:23:23","AP02EDTM":"2022-05-16 09:23:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-16","EOSDY":1096,"LSTALVDT":"2022-05-31","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2315,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.04987,"AVALU":"mg/L","BASE2":9.02657,"BASE":9.31411,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02331,"PCHG2":0.25819,"CHG":-0.26423,"PCHG":-2.83693,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-17 15:23:23","ADY":671,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-286","SUBJID":"id-286","SITEID":"CHN-2","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.63472,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-16 15:23:23","TRTEDTM":"2022-05-16 09:23:23","TRT01SDTM":"2019-05-16 15:23:23","TRT01EDTM":"2021-05-16 03:23:23","TRT02SDTM":"2021-05-16 03:23:23","TRT02EDTM":"2022-05-16 09:23:23","AP01SDTM":"2019-05-16 15:23:23","AP01EDTM":"2021-05-16 03:23:23","AP02SDTM":"2021-05-16 03:23:23","AP02EDTM":"2022-05-16 09:23:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-16","EOSDY":1096,"LSTALVDT":"2022-05-31","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7952,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04046,"AVALU":"g/L","BASE2":3.04046,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2019-07-02 15:23:23","ADY":47,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-286","SUBJID":"id-286","SITEID":"CHN-2","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.63472,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-16 15:23:23","TRTEDTM":"2022-05-16 09:23:23","TRT01SDTM":"2019-05-16 15:23:23","TRT01EDTM":"2021-05-16 03:23:23","TRT02SDTM":"2021-05-16 03:23:23","TRT02EDTM":"2022-05-16 09:23:23","AP01SDTM":"2019-05-16 15:23:23","AP01EDTM":"2021-05-16 03:23:23","AP02SDTM":"2021-05-16 03:23:23","AP02EDTM":"2022-05-16 09:23:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-16","EOSDY":1096,"LSTALVDT":"2022-05-31","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":122,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91648,"AVALU":"g/L","BASE2":3.04046,"BASE":2.91648,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.12398,"PCHG2":-4.07772,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-09 15:23:23","ADY":116,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-286","SUBJID":"id-286","SITEID":"CHN-2","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.63472,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-16 15:23:23","TRTEDTM":"2022-05-16 09:23:23","TRT01SDTM":"2019-05-16 15:23:23","TRT01EDTM":"2021-05-16 03:23:23","TRT02SDTM":"2021-05-16 03:23:23","TRT02EDTM":"2022-05-16 09:23:23","AP01SDTM":"2019-05-16 15:23:23","AP01EDTM":"2021-05-16 03:23:23","AP02SDTM":"2021-05-16 03:23:23","AP02EDTM":"2022-05-16 09:23:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-16","EOSDY":1096,"LSTALVDT":"2022-05-31","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2753,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94352,"AVALU":"g/L","BASE2":3.04046,"BASE":2.91648,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09694,"PCHG2":-3.18836,"CHG":0.02704,"PCHG":0.92716,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-06 15:23:23","ADY":479,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-286","SUBJID":"id-286","SITEID":"CHN-2","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.63472,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-16 15:23:23","TRTEDTM":"2022-05-16 09:23:23","TRT01SDTM":"2019-05-16 15:23:23","TRT01EDTM":"2021-05-16 03:23:23","TRT02SDTM":"2021-05-16 03:23:23","TRT02EDTM":"2022-05-16 09:23:23","AP01SDTM":"2019-05-16 15:23:23","AP01EDTM":"2021-05-16 03:23:23","AP02SDTM":"2021-05-16 03:23:23","AP02EDTM":"2022-05-16 09:23:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-16","EOSDY":1096,"LSTALVDT":"2022-05-31","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7147,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82104,"AVALU":"g/L","BASE2":3.04046,"BASE":2.91648,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21942,"PCHG2":-7.21657,"CHG":-0.09544,"PCHG":-3.27228,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-02 15:23:23","ADY":628,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-286","SUBJID":"id-286","SITEID":"CHN-2","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.63472,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-16 15:23:23","TRTEDTM":"2022-05-16 09:23:23","TRT01SDTM":"2019-05-16 15:23:23","TRT01EDTM":"2021-05-16 03:23:23","TRT02SDTM":"2021-05-16 03:23:23","TRT02EDTM":"2022-05-16 09:23:23","AP01SDTM":"2019-05-16 15:23:23","AP01EDTM":"2021-05-16 03:23:23","AP02SDTM":"2021-05-16 03:23:23","AP02EDTM":"2022-05-16 09:23:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-16","EOSDY":1096,"LSTALVDT":"2022-05-31","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2120,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.66861,"AVALU":"g/L","BASE2":3.04046,"BASE":2.91648,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.37185,"PCHG2":-12.23,"CHG":-0.24787,"PCHG":-8.49884,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-19 15:23:23","ADY":645,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-286","SUBJID":"id-286","SITEID":"CHN-2","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.63472,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-16 15:23:23","TRTEDTM":"2022-05-16 09:23:23","TRT01SDTM":"2019-05-16 15:23:23","TRT01EDTM":"2021-05-16 03:23:23","TRT02SDTM":"2021-05-16 03:23:23","TRT02EDTM":"2022-05-16 09:23:23","AP01SDTM":"2019-05-16 15:23:23","AP01EDTM":"2021-05-16 03:23:23","AP02SDTM":"2021-05-16 03:23:23","AP02EDTM":"2022-05-16 09:23:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-16","EOSDY":1096,"LSTALVDT":"2022-05-31","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5053,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81748,"AVALU":"g/L","BASE2":3.04046,"BASE":2.91648,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.22298,"PCHG2":-7.3336,"CHG":-0.09899,"PCHG":-3.39429,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-14 15:23:23","ADY":668,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-286","SUBJID":"id-286","SITEID":"CHN-2","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.63472,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-16 15:23:23","TRTEDTM":"2022-05-16 09:23:23","TRT01SDTM":"2019-05-16 15:23:23","TRT01EDTM":"2021-05-16 03:23:23","TRT02SDTM":"2021-05-16 03:23:23","TRT02EDTM":"2022-05-16 09:23:23","AP01SDTM":"2019-05-16 15:23:23","AP01EDTM":"2021-05-16 03:23:23","AP02SDTM":"2021-05-16 03:23:23","AP02EDTM":"2022-05-16 09:23:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-16","EOSDY":1096,"LSTALVDT":"2022-05-31","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7759,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.08342,"AVALU":"g/L","BASE2":3.04046,"BASE":2.91648,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04296,"PCHG2":1.41294,"CHG":0.16694,"PCHG":5.72407,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-03-17 15:23:23","ADY":671,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-292","SUBJID":"id-292","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.87128,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-07","TRTSDTM":"2020-07-10 08:44:25","TRTEDTM":"2023-07-11 02:44:25","TRT01SDTM":"2020-07-10 08:44:25","TRT01EDTM":"2022-07-10 20:44:25","TRT02SDTM":"2022-07-10 20:44:25","TRT02EDTM":"2023-07-11 02:44:25","AP01SDTM":"2020-07-10 08:44:25","AP01EDTM":"2022-07-10 20:44:25","AP02SDTM":"2022-07-10 20:44:25","AP02EDTM":"2023-07-11 02:44:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-11","EOSDY":1096,"LSTALVDT":"2023-07-24","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7115,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.41001,"AVALU":"U/L","BASE2":25.41001,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-22 08:44:25","ADY":227,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-292","SUBJID":"id-292","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.87128,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-07","TRTSDTM":"2020-07-10 08:44:25","TRTEDTM":"2023-07-11 02:44:25","TRT01SDTM":"2020-07-10 08:44:25","TRT01EDTM":"2022-07-10 20:44:25","TRT02SDTM":"2022-07-10 20:44:25","TRT02EDTM":"2023-07-11 02:44:25","AP01SDTM":"2020-07-10 08:44:25","AP01EDTM":"2022-07-10 20:44:25","AP02SDTM":"2022-07-10 20:44:25","AP02EDTM":"2023-07-11 02:44:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-11","EOSDY":1096,"LSTALVDT":"2023-07-24","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6419,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.27325,"AVALU":"U/L","BASE2":25.41001,"BASE":16.27325,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-9.13676,"PCHG2":-35.95734,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-19 08:44:25","ADY":374,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-292","SUBJID":"id-292","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.87128,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-07","TRTSDTM":"2020-07-10 08:44:25","TRTEDTM":"2023-07-11 02:44:25","TRT01SDTM":"2020-07-10 08:44:25","TRT01EDTM":"2022-07-10 20:44:25","TRT02SDTM":"2022-07-10 20:44:25","TRT02EDTM":"2023-07-11 02:44:25","AP01SDTM":"2020-07-10 08:44:25","AP01EDTM":"2022-07-10 20:44:25","AP02SDTM":"2022-07-10 20:44:25","AP02EDTM":"2023-07-11 02:44:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-11","EOSDY":1096,"LSTALVDT":"2023-07-24","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3985,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.03723,"AVALU":"U/L","BASE2":25.41001,"BASE":16.27325,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.37278,"PCHG2":-17.2089,"CHG":4.76398,"PCHG":29.27493,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-12 08:44:25","ADY":429,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-292","SUBJID":"id-292","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.87128,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-07","TRTSDTM":"2020-07-10 08:44:25","TRTEDTM":"2023-07-11 02:44:25","TRT01SDTM":"2020-07-10 08:44:25","TRT01EDTM":"2022-07-10 20:44:25","TRT02SDTM":"2022-07-10 20:44:25","TRT02EDTM":"2023-07-11 02:44:25","AP01SDTM":"2020-07-10 08:44:25","AP01EDTM":"2022-07-10 20:44:25","AP02SDTM":"2022-07-10 20:44:25","AP02EDTM":"2023-07-11 02:44:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-11","EOSDY":1096,"LSTALVDT":"2023-07-24","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5490,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.6572,"AVALU":"U/L","BASE2":25.41001,"BASE":16.27325,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.75281,"PCHG2":-30.51086,"CHG":1.38395,"PCHG":8.50445,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-04 08:44:25","ADY":908,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-292","SUBJID":"id-292","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.87128,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-07","TRTSDTM":"2020-07-10 08:44:25","TRTEDTM":"2023-07-11 02:44:25","TRT01SDTM":"2020-07-10 08:44:25","TRT01EDTM":"2022-07-10 20:44:25","TRT02SDTM":"2022-07-10 20:44:25","TRT02EDTM":"2023-07-11 02:44:25","AP01SDTM":"2020-07-10 08:44:25","AP01EDTM":"2022-07-10 20:44:25","AP02SDTM":"2022-07-10 20:44:25","AP02EDTM":"2023-07-11 02:44:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-11","EOSDY":1096,"LSTALVDT":"2023-07-24","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":425,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.43991,"AVALU":"U/L","BASE2":25.41001,"BASE":16.27325,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.9701,"PCHG2":-27.43051,"CHG":2.16667,"PCHG":13.31429,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-10 08:44:25","ADY":945,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-292","SUBJID":"id-292","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.87128,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-07","TRTSDTM":"2020-07-10 08:44:25","TRTEDTM":"2023-07-11 02:44:25","TRT01SDTM":"2020-07-10 08:44:25","TRT01EDTM":"2022-07-10 20:44:25","TRT02SDTM":"2022-07-10 20:44:25","TRT02EDTM":"2023-07-11 02:44:25","AP01SDTM":"2020-07-10 08:44:25","AP01EDTM":"2022-07-10 20:44:25","AP02SDTM":"2022-07-10 20:44:25","AP02EDTM":"2023-07-11 02:44:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-11","EOSDY":1096,"LSTALVDT":"2023-07-24","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1533,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.40039,"AVALU":"U/L","BASE2":25.41001,"BASE":16.27325,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-25.00962,"PCHG2":-98.42427,"CHG":-15.87285,"PCHG":-97.53956,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2023-05-04 08:44:25","ADY":1028,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-292","SUBJID":"id-292","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.87128,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-07","TRTSDTM":"2020-07-10 08:44:25","TRTEDTM":"2023-07-11 02:44:25","TRT01SDTM":"2020-07-10 08:44:25","TRT01EDTM":"2022-07-10 20:44:25","TRT02SDTM":"2022-07-10 20:44:25","TRT02EDTM":"2023-07-11 02:44:25","AP01SDTM":"2020-07-10 08:44:25","AP01EDTM":"2022-07-10 20:44:25","AP02SDTM":"2022-07-10 20:44:25","AP02EDTM":"2023-07-11 02:44:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-11","EOSDY":1096,"LSTALVDT":"2023-07-24","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3718,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":36.008,"AVALU":"U/L","BASE2":25.41001,"BASE":16.27325,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.59799,"PCHG2":41.70793,"CHG":19.73476,"PCHG":121.27116,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-21 08:44:25","ADY":1045,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-292","SUBJID":"id-292","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.87128,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-07","TRTSDTM":"2020-07-10 08:44:25","TRTEDTM":"2023-07-11 02:44:25","TRT01SDTM":"2020-07-10 08:44:25","TRT01EDTM":"2022-07-10 20:44:25","TRT02SDTM":"2022-07-10 20:44:25","TRT02EDTM":"2023-07-11 02:44:25","AP01SDTM":"2020-07-10 08:44:25","AP01EDTM":"2022-07-10 20:44:25","AP02SDTM":"2022-07-10 20:44:25","AP02EDTM":"2023-07-11 02:44:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-11","EOSDY":1096,"LSTALVDT":"2023-07-24","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1357,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.73805,"AVALU":"mg/L","BASE2":8.73805,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-22 08:44:25","ADY":227,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-292","SUBJID":"id-292","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.87128,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-07","TRTSDTM":"2020-07-10 08:44:25","TRTEDTM":"2023-07-11 02:44:25","TRT01SDTM":"2020-07-10 08:44:25","TRT01EDTM":"2022-07-10 20:44:25","TRT02SDTM":"2022-07-10 20:44:25","TRT02EDTM":"2023-07-11 02:44:25","AP01SDTM":"2020-07-10 08:44:25","AP01EDTM":"2022-07-10 20:44:25","AP02SDTM":"2022-07-10 20:44:25","AP02EDTM":"2023-07-11 02:44:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-11","EOSDY":1096,"LSTALVDT":"2023-07-24","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6713,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.81445,"AVALU":"mg/L","BASE2":8.73805,"BASE":8.81445,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.07639,"PCHG2":0.87426,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-19 08:44:25","ADY":374,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-292","SUBJID":"id-292","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.87128,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-07","TRTSDTM":"2020-07-10 08:44:25","TRTEDTM":"2023-07-11 02:44:25","TRT01SDTM":"2020-07-10 08:44:25","TRT01EDTM":"2022-07-10 20:44:25","TRT02SDTM":"2022-07-10 20:44:25","TRT02EDTM":"2023-07-11 02:44:25","AP01SDTM":"2020-07-10 08:44:25","AP01EDTM":"2022-07-10 20:44:25","AP02SDTM":"2022-07-10 20:44:25","AP02EDTM":"2023-07-11 02:44:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-11","EOSDY":1096,"LSTALVDT":"2023-07-24","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4681,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.91151,"AVALU":"mg/L","BASE2":8.73805,"BASE":8.81445,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17346,"PCHG2":1.98512,"CHG":0.09707,"PCHG":1.10123,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-12 08:44:25","ADY":429,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-292","SUBJID":"id-292","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.87128,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-07","TRTSDTM":"2020-07-10 08:44:25","TRTEDTM":"2023-07-11 02:44:25","TRT01SDTM":"2020-07-10 08:44:25","TRT01EDTM":"2022-07-10 20:44:25","TRT02SDTM":"2022-07-10 20:44:25","TRT02EDTM":"2023-07-11 02:44:25","AP01SDTM":"2020-07-10 08:44:25","AP01EDTM":"2022-07-10 20:44:25","AP02SDTM":"2022-07-10 20:44:25","AP02EDTM":"2023-07-11 02:44:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-11","EOSDY":1096,"LSTALVDT":"2023-07-24","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2790,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.62261,"AVALU":"mg/L","BASE2":8.73805,"BASE":8.81445,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.88456,"PCHG2":21.56725,"CHG":1.80816,"PCHG":20.51364,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2023-01-04 08:44:25","ADY":908,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-292","SUBJID":"id-292","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.87128,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-07","TRTSDTM":"2020-07-10 08:44:25","TRTEDTM":"2023-07-11 02:44:25","TRT01SDTM":"2020-07-10 08:44:25","TRT01EDTM":"2022-07-10 20:44:25","TRT02SDTM":"2022-07-10 20:44:25","TRT02EDTM":"2023-07-11 02:44:25","AP01SDTM":"2020-07-10 08:44:25","AP01EDTM":"2022-07-10 20:44:25","AP02SDTM":"2022-07-10 20:44:25","AP02EDTM":"2023-07-11 02:44:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-11","EOSDY":1096,"LSTALVDT":"2023-07-24","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3505,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.49266,"AVALU":"mg/L","BASE2":8.73805,"BASE":8.81445,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.24539,"PCHG2":-2.8083,"CHG":-0.32178,"PCHG":-3.65064,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-10 08:44:25","ADY":945,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-292","SUBJID":"id-292","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.87128,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-07","TRTSDTM":"2020-07-10 08:44:25","TRTEDTM":"2023-07-11 02:44:25","TRT01SDTM":"2020-07-10 08:44:25","TRT01EDTM":"2022-07-10 20:44:25","TRT02SDTM":"2022-07-10 20:44:25","TRT02EDTM":"2023-07-11 02:44:25","AP01SDTM":"2020-07-10 08:44:25","AP01EDTM":"2022-07-10 20:44:25","AP02SDTM":"2022-07-10 20:44:25","AP02EDTM":"2023-07-11 02:44:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-11","EOSDY":1096,"LSTALVDT":"2023-07-24","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":534,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.58743,"AVALU":"mg/L","BASE2":8.73805,"BASE":8.81445,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.84937,"PCHG2":9.72041,"CHG":0.77298,"PCHG":8.76948,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-04 08:44:25","ADY":1028,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-292","SUBJID":"id-292","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.87128,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-07","TRTSDTM":"2020-07-10 08:44:25","TRTEDTM":"2023-07-11 02:44:25","TRT01SDTM":"2020-07-10 08:44:25","TRT01EDTM":"2022-07-10 20:44:25","TRT02SDTM":"2022-07-10 20:44:25","TRT02EDTM":"2023-07-11 02:44:25","AP01SDTM":"2020-07-10 08:44:25","AP01EDTM":"2022-07-10 20:44:25","AP02SDTM":"2022-07-10 20:44:25","AP02EDTM":"2023-07-11 02:44:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-11","EOSDY":1096,"LSTALVDT":"2023-07-24","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2743,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.21357,"AVALU":"mg/L","BASE2":8.73805,"BASE":8.81445,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.47552,"PCHG2":16.88614,"CHG":1.39913,"PCHG":15.87311,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2023-05-21 08:44:25","ADY":1045,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-292","SUBJID":"id-292","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.87128,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-07","TRTSDTM":"2020-07-10 08:44:25","TRTEDTM":"2023-07-11 02:44:25","TRT01SDTM":"2020-07-10 08:44:25","TRT01EDTM":"2022-07-10 20:44:25","TRT02SDTM":"2022-07-10 20:44:25","TRT02EDTM":"2023-07-11 02:44:25","AP01SDTM":"2020-07-10 08:44:25","AP01EDTM":"2022-07-10 20:44:25","AP02SDTM":"2022-07-10 20:44:25","AP02EDTM":"2023-07-11 02:44:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-11","EOSDY":1096,"LSTALVDT":"2023-07-24","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7924,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83738,"AVALU":"g/L","BASE2":2.83738,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-22 08:44:25","ADY":227,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-292","SUBJID":"id-292","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.87128,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-07","TRTSDTM":"2020-07-10 08:44:25","TRTEDTM":"2023-07-11 02:44:25","TRT01SDTM":"2020-07-10 08:44:25","TRT01EDTM":"2022-07-10 20:44:25","TRT02SDTM":"2022-07-10 20:44:25","TRT02EDTM":"2023-07-11 02:44:25","AP01SDTM":"2020-07-10 08:44:25","AP01EDTM":"2022-07-10 20:44:25","AP02SDTM":"2022-07-10 20:44:25","AP02EDTM":"2023-07-11 02:44:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-11","EOSDY":1096,"LSTALVDT":"2023-07-24","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":239,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.61212,"AVALU":"g/L","BASE2":2.83738,"BASE":2.61212,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.22526,"PCHG2":-7.93906,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-19 08:44:25","ADY":374,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-292","SUBJID":"id-292","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.87128,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-07","TRTSDTM":"2020-07-10 08:44:25","TRTEDTM":"2023-07-11 02:44:25","TRT01SDTM":"2020-07-10 08:44:25","TRT01EDTM":"2022-07-10 20:44:25","TRT02SDTM":"2022-07-10 20:44:25","TRT02EDTM":"2023-07-11 02:44:25","AP01SDTM":"2020-07-10 08:44:25","AP01EDTM":"2022-07-10 20:44:25","AP02SDTM":"2022-07-10 20:44:25","AP02EDTM":"2023-07-11 02:44:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-11","EOSDY":1096,"LSTALVDT":"2023-07-24","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3226,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86433,"AVALU":"g/L","BASE2":2.83738,"BASE":2.61212,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02695,"PCHG2":0.9498,"CHG":0.25221,"PCHG":9.65541,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-12 08:44:25","ADY":429,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-292","SUBJID":"id-292","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.87128,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-07","TRTSDTM":"2020-07-10 08:44:25","TRTEDTM":"2023-07-11 02:44:25","TRT01SDTM":"2020-07-10 08:44:25","TRT01EDTM":"2022-07-10 20:44:25","TRT02SDTM":"2022-07-10 20:44:25","TRT02EDTM":"2023-07-11 02:44:25","AP01SDTM":"2020-07-10 08:44:25","AP01EDTM":"2022-07-10 20:44:25","AP02SDTM":"2022-07-10 20:44:25","AP02EDTM":"2023-07-11 02:44:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-11","EOSDY":1096,"LSTALVDT":"2023-07-24","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5261,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83748,"AVALU":"g/L","BASE2":2.83738,"BASE":2.61212,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0001,"PCHG2":0.00339,"CHG":0.22536,"PCHG":8.62738,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-04 08:44:25","ADY":908,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-292","SUBJID":"id-292","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.87128,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-07","TRTSDTM":"2020-07-10 08:44:25","TRTEDTM":"2023-07-11 02:44:25","TRT01SDTM":"2020-07-10 08:44:25","TRT01EDTM":"2022-07-10 20:44:25","TRT02SDTM":"2022-07-10 20:44:25","TRT02EDTM":"2023-07-11 02:44:25","AP01SDTM":"2020-07-10 08:44:25","AP01EDTM":"2022-07-10 20:44:25","AP02SDTM":"2022-07-10 20:44:25","AP02EDTM":"2023-07-11 02:44:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-11","EOSDY":1096,"LSTALVDT":"2023-07-24","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2087,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79597,"AVALU":"g/L","BASE2":2.83738,"BASE":2.61212,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04141,"PCHG2":-1.45957,"CHG":0.18385,"PCHG":7.03825,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-10 08:44:25","ADY":945,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-292","SUBJID":"id-292","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.87128,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-07","TRTSDTM":"2020-07-10 08:44:25","TRTEDTM":"2023-07-11 02:44:25","TRT01SDTM":"2020-07-10 08:44:25","TRT01EDTM":"2022-07-10 20:44:25","TRT02SDTM":"2022-07-10 20:44:25","TRT02EDTM":"2023-07-11 02:44:25","AP01SDTM":"2020-07-10 08:44:25","AP01EDTM":"2022-07-10 20:44:25","AP02SDTM":"2022-07-10 20:44:25","AP02EDTM":"2023-07-11 02:44:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-11","EOSDY":1096,"LSTALVDT":"2023-07-24","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5592,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93898,"AVALU":"g/L","BASE2":2.83738,"BASE":2.61212,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1016,"PCHG2":3.58073,"CHG":0.32686,"PCHG":12.51322,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-04 08:44:25","ADY":1028,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-292","SUBJID":"id-292","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":7.87128,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-07","TRTSDTM":"2020-07-10 08:44:25","TRTEDTM":"2023-07-11 02:44:25","TRT01SDTM":"2020-07-10 08:44:25","TRT01EDTM":"2022-07-10 20:44:25","TRT02SDTM":"2022-07-10 20:44:25","TRT02EDTM":"2023-07-11 02:44:25","AP01SDTM":"2020-07-10 08:44:25","AP01EDTM":"2022-07-10 20:44:25","AP02SDTM":"2022-07-10 20:44:25","AP02EDTM":"2023-07-11 02:44:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-11","EOSDY":1096,"LSTALVDT":"2023-07-24","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7580,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81805,"AVALU":"g/L","BASE2":2.83738,"BASE":2.61212,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01934,"PCHG2":-0.68153,"CHG":0.20592,"PCHG":7.88339,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-21 08:44:25","ADY":1045,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-332","SUBJID":"id-332","SITEID":"CHN-2","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.21853,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 07:50:23","TRT01SDTM":"2019-10-08 07:50:23","AP01SDTM":"2019-10-08 07:50:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1913,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.49304,"AVALU":"U/L","BASE2":11.49304,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-19 07:50:23","ADY":72,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-332","SUBJID":"id-332","SITEID":"CHN-2","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.21853,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 07:50:23","TRT01SDTM":"2019-10-08 07:50:23","AP01SDTM":"2019-10-08 07:50:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4658,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.95881,"AVALU":"U/L","BASE2":11.49304,"BASE":19.95881,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":8.46577,"PCHG2":73.66001,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-10 07:50:23","ADY":94,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-332","SUBJID":"id-332","SITEID":"CHN-2","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.21853,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 07:50:23","TRT01SDTM":"2019-10-08 07:50:23","AP01SDTM":"2019-10-08 07:50:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5469,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.033,"AVALU":"U/L","BASE2":11.49304,"BASE":19.95881,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.53997,"PCHG2":56.90373,"CHG":-1.92581,"PCHG":-9.6489,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-11 07:50:23","ADY":95,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-332","SUBJID":"id-332","SITEID":"CHN-2","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.21853,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 07:50:23","TRT01SDTM":"2019-10-08 07:50:23","AP01SDTM":"2019-10-08 07:50:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":891,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.17207,"AVALU":"U/L","BASE2":11.49304,"BASE":19.95881,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.67904,"PCHG2":5.90826,"CHG":-7.78673,"PCHG":-39.01402,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-19 07:50:23","ADY":134,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-332","SUBJID":"id-332","SITEID":"CHN-2","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.21853,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 07:50:23","TRT01SDTM":"2019-10-08 07:50:23","AP01SDTM":"2019-10-08 07:50:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7834,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.84765,"AVALU":"U/L","BASE2":11.49304,"BASE":19.95881,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.35462,"PCHG2":46.59009,"CHG":-3.11115,"PCHG":-15.58788,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-27 07:50:23","ADY":171,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-332","SUBJID":"id-332","SITEID":"CHN-2","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.21853,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 07:50:23","TRT01SDTM":"2019-10-08 07:50:23","AP01SDTM":"2019-10-08 07:50:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5065,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.80172,"AVALU":"U/L","BASE2":11.49304,"BASE":19.95881,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.30869,"PCHG2":107.09691,"CHG":3.84292,"PCHG":19.25424,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-26 07:50:23","ADY":201,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-332","SUBJID":"id-332","SITEID":"CHN-2","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.21853,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 07:50:23","TRT01SDTM":"2019-10-08 07:50:23","AP01SDTM":"2019-10-08 07:50:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5591,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.37284,"AVALU":"U/L","BASE2":11.49304,"BASE":19.95881,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.87981,"PCHG2":120.76711,"CHG":5.41404,"PCHG":27.12605,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-26 07:50:23","ADY":231,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-332","SUBJID":"id-332","SITEID":"CHN-2","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.21853,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 07:50:23","TRT01SDTM":"2019-10-08 07:50:23","AP01SDTM":"2019-10-08 07:50:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2556,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.6777,"AVALU":"mg/L","BASE2":9.6777,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2019-12-19 07:50:23","ADY":72,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-332","SUBJID":"id-332","SITEID":"CHN-2","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.21853,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 07:50:23","TRT01SDTM":"2019-10-08 07:50:23","AP01SDTM":"2019-10-08 07:50:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4259,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.78863,"AVALU":"mg/L","BASE2":9.6777,"BASE":10.78863,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.11093,"PCHG2":11.47932,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-01-10 07:50:23","ADY":94,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-332","SUBJID":"id-332","SITEID":"CHN-2","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.21853,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 07:50:23","TRT01SDTM":"2019-10-08 07:50:23","AP01SDTM":"2019-10-08 07:50:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5460,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.28652,"AVALU":"mg/L","BASE2":9.6777,"BASE":10.78863,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.39118,"PCHG2":-14.37511,"CHG":-2.50211,"PCHG":-23.19214,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-01-11 07:50:23","ADY":95,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-332","SUBJID":"id-332","SITEID":"CHN-2","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.21853,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 07:50:23","TRT01SDTM":"2019-10-08 07:50:23","AP01SDTM":"2019-10-08 07:50:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4809,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.24748,"AVALU":"mg/L","BASE2":9.6777,"BASE":10.78863,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.43022,"PCHG2":-4.44549,"CHG":-1.54115,"PCHG":-14.28499,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-02-19 07:50:23","ADY":134,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-332","SUBJID":"id-332","SITEID":"CHN-2","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.21853,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 07:50:23","TRT01SDTM":"2019-10-08 07:50:23","AP01SDTM":"2019-10-08 07:50:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":546,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.02682,"AVALU":"mg/L","BASE2":9.6777,"BASE":10.78863,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.34912,"PCHG2":3.60751,"CHG":-0.76181,"PCHG":-7.06123,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-03-27 07:50:23","ADY":171,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-332","SUBJID":"id-332","SITEID":"CHN-2","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.21853,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 07:50:23","TRT01SDTM":"2019-10-08 07:50:23","AP01SDTM":"2019-10-08 07:50:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":662,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.5559,"AVALU":"mg/L","BASE2":9.6777,"BASE":10.78863,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1218,"PCHG2":-1.25857,"CHG":-1.23273,"PCHG":-11.42623,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-04-26 07:50:23","ADY":201,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-332","SUBJID":"id-332","SITEID":"CHN-2","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.21853,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 07:50:23","TRT01SDTM":"2019-10-08 07:50:23","AP01SDTM":"2019-10-08 07:50:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8365,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.2895,"AVALU":"mg/L","BASE2":9.6777,"BASE":10.78863,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.38819,"PCHG2":-14.34426,"CHG":-2.49913,"PCHG":-23.16446,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-05-26 07:50:23","ADY":231,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-332","SUBJID":"id-332","SITEID":"CHN-2","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.21853,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 07:50:23","TRT01SDTM":"2019-10-08 07:50:23","AP01SDTM":"2019-10-08 07:50:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":78,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90551,"AVALU":"g/L","BASE2":2.90551,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-19 07:50:23","ADY":72,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-332","SUBJID":"id-332","SITEID":"CHN-2","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.21853,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 07:50:23","TRT01SDTM":"2019-10-08 07:50:23","AP01SDTM":"2019-10-08 07:50:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1435,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77182,"AVALU":"g/L","BASE2":2.90551,"BASE":2.77182,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.1337,"PCHG2":-4.60145,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-10 07:50:23","ADY":94,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-332","SUBJID":"id-332","SITEID":"CHN-2","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.21853,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 07:50:23","TRT01SDTM":"2019-10-08 07:50:23","AP01SDTM":"2019-10-08 07:50:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3674,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85579,"AVALU":"g/L","BASE2":2.90551,"BASE":2.77182,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04972,"PCHG2":-1.7113,"CHG":0.08397,"PCHG":3.02955,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-11 07:50:23","ADY":95,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-332","SUBJID":"id-332","SITEID":"CHN-2","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.21853,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 07:50:23","TRT01SDTM":"2019-10-08 07:50:23","AP01SDTM":"2019-10-08 07:50:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4174,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.07474,"AVALU":"g/L","BASE2":2.90551,"BASE":2.77182,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16923,"PCHG2":5.82441,"CHG":0.30292,"PCHG":10.92874,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-02-19 07:50:23","ADY":134,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-332","SUBJID":"id-332","SITEID":"CHN-2","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.21853,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 07:50:23","TRT01SDTM":"2019-10-08 07:50:23","AP01SDTM":"2019-10-08 07:50:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7706,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89262,"AVALU":"g/L","BASE2":2.90551,"BASE":2.77182,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0129,"PCHG2":-0.4439,"CHG":0.1208,"PCHG":4.35808,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-27 07:50:23","ADY":171,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-332","SUBJID":"id-332","SITEID":"CHN-2","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.21853,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 07:50:23","TRT01SDTM":"2019-10-08 07:50:23","AP01SDTM":"2019-10-08 07:50:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":74,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88973,"AVALU":"g/L","BASE2":2.90551,"BASE":2.77182,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01579,"PCHG2":-0.54334,"CHG":0.11791,"PCHG":4.25385,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-26 07:50:23","ADY":201,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-332","SUBJID":"id-332","SITEID":"CHN-2","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.21853,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 07:50:23","TRT01SDTM":"2019-10-08 07:50:23","AP01SDTM":"2019-10-08 07:50:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2124,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86872,"AVALU":"g/L","BASE2":2.90551,"BASE":2.77182,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0368,"PCHG2":-1.26649,"CHG":0.0969,"PCHG":3.49582,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-26 07:50:23","ADY":231,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-34","SUBJID":"id-34","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.61602,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-17 09:56:10","TRTEDTM":"2022-07-17 03:56:10","TRT01SDTM":"2019-07-17 09:56:10","TRT01EDTM":"2021-07-16 21:56:10","TRT02SDTM":"2021-07-16 21:56:10","TRT02EDTM":"2022-07-17 03:56:10","AP01SDTM":"2019-07-17 09:56:10","AP01EDTM":"2021-07-16 21:56:10","AP02SDTM":"2021-07-16 21:56:10","AP02EDTM":"2022-07-17 03:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-28","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":377,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.65555,"AVALU":"U/L","BASE2":32.65555,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-26 09:56:10","ADY":71,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-34","SUBJID":"id-34","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.61602,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-17 09:56:10","TRTEDTM":"2022-07-17 03:56:10","TRT01SDTM":"2019-07-17 09:56:10","TRT01EDTM":"2021-07-16 21:56:10","TRT02SDTM":"2021-07-16 21:56:10","TRT02EDTM":"2022-07-17 03:56:10","AP01SDTM":"2019-07-17 09:56:10","AP01EDTM":"2021-07-16 21:56:10","AP02SDTM":"2021-07-16 21:56:10","AP02EDTM":"2022-07-17 03:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-28","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7703,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.90819,"AVALU":"U/L","BASE2":32.65555,"BASE":12.90819,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-19.74736,"PCHG2":-60.47167,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-26 09:56:10","ADY":284,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-34","SUBJID":"id-34","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.61602,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-17 09:56:10","TRTEDTM":"2022-07-17 03:56:10","TRT01SDTM":"2019-07-17 09:56:10","TRT01EDTM":"2021-07-16 21:56:10","TRT02SDTM":"2021-07-16 21:56:10","TRT02EDTM":"2022-07-17 03:56:10","AP01SDTM":"2019-07-17 09:56:10","AP01EDTM":"2021-07-16 21:56:10","AP02SDTM":"2021-07-16 21:56:10","AP02EDTM":"2022-07-17 03:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-28","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3859,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.21699,"AVALU":"U/L","BASE2":32.65555,"BASE":12.90819,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-15.43856,"PCHG2":-47.27699,"CHG":4.3088,"PCHG":33.38032,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-08 09:56:10","ADY":419,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-34","SUBJID":"id-34","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.61602,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-17 09:56:10","TRTEDTM":"2022-07-17 03:56:10","TRT01SDTM":"2019-07-17 09:56:10","TRT01EDTM":"2021-07-16 21:56:10","TRT02SDTM":"2021-07-16 21:56:10","TRT02EDTM":"2022-07-17 03:56:10","AP01SDTM":"2019-07-17 09:56:10","AP01EDTM":"2021-07-16 21:56:10","AP02SDTM":"2021-07-16 21:56:10","AP02EDTM":"2022-07-17 03:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-28","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2532,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":38.61054,"AVALU":"U/L","BASE2":32.65555,"BASE":12.90819,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.955,"PCHG2":18.23578,"CHG":25.70235,"PCHG":199.11659,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-16 09:56:10","ADY":457,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-34","SUBJID":"id-34","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.61602,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-17 09:56:10","TRTEDTM":"2022-07-17 03:56:10","TRT01SDTM":"2019-07-17 09:56:10","TRT01EDTM":"2021-07-16 21:56:10","TRT02SDTM":"2021-07-16 21:56:10","TRT02EDTM":"2022-07-17 03:56:10","AP01SDTM":"2019-07-17 09:56:10","AP01EDTM":"2021-07-16 21:56:10","AP02SDTM":"2021-07-16 21:56:10","AP02EDTM":"2022-07-17 03:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-28","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":470,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.73684,"AVALU":"U/L","BASE2":32.65555,"BASE":12.90819,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-30.91871,"PCHG2":-94.68135,"CHG":-11.17136,"PCHG":-86.5447,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-12-19 09:56:10","ADY":521,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-34","SUBJID":"id-34","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.61602,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-17 09:56:10","TRTEDTM":"2022-07-17 03:56:10","TRT01SDTM":"2019-07-17 09:56:10","TRT01EDTM":"2021-07-16 21:56:10","TRT02SDTM":"2021-07-16 21:56:10","TRT02EDTM":"2022-07-17 03:56:10","AP01SDTM":"2019-07-17 09:56:10","AP01EDTM":"2021-07-16 21:56:10","AP02SDTM":"2021-07-16 21:56:10","AP02EDTM":"2022-07-17 03:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-28","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3841,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.63994,"AVALU":"U/L","BASE2":32.65555,"BASE":12.90819,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-25.01561,"PCHG2":-76.60448,"CHG":-5.26826,"PCHG":-40.81327,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-25 09:56:10","ADY":739,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-34","SUBJID":"id-34","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.61602,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-17 09:56:10","TRTEDTM":"2022-07-17 03:56:10","TRT01SDTM":"2019-07-17 09:56:10","TRT01EDTM":"2021-07-16 21:56:10","TRT02SDTM":"2021-07-16 21:56:10","TRT02EDTM":"2022-07-17 03:56:10","AP01SDTM":"2019-07-17 09:56:10","AP01EDTM":"2021-07-16 21:56:10","AP02SDTM":"2021-07-16 21:56:10","AP02EDTM":"2022-07-17 03:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-28","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6782,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.80694,"AVALU":"U/L","BASE2":32.65555,"BASE":12.90819,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-20.84861,"PCHG2":-63.84401,"CHG":-1.10125,"PCHG":-8.53144,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-27 09:56:10","ADY":925,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-34","SUBJID":"id-34","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.61602,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-17 09:56:10","TRTEDTM":"2022-07-17 03:56:10","TRT01SDTM":"2019-07-17 09:56:10","TRT01EDTM":"2021-07-16 21:56:10","TRT02SDTM":"2021-07-16 21:56:10","TRT02EDTM":"2022-07-17 03:56:10","AP01SDTM":"2019-07-17 09:56:10","AP01EDTM":"2021-07-16 21:56:10","AP02SDTM":"2021-07-16 21:56:10","AP02EDTM":"2022-07-17 03:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-28","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2266,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.06635,"AVALU":"mg/L","BASE2":8.06635,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-26 09:56:10","ADY":71,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-34","SUBJID":"id-34","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.61602,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-17 09:56:10","TRTEDTM":"2022-07-17 03:56:10","TRT01SDTM":"2019-07-17 09:56:10","TRT01EDTM":"2021-07-16 21:56:10","TRT02SDTM":"2021-07-16 21:56:10","TRT02EDTM":"2022-07-17 03:56:10","AP01SDTM":"2019-07-17 09:56:10","AP01EDTM":"2021-07-16 21:56:10","AP02SDTM":"2021-07-16 21:56:10","AP02EDTM":"2022-07-17 03:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-28","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4137,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.74266,"AVALU":"mg/L","BASE2":8.06635,"BASE":8.74266,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.67631,"PCHG2":8.38437,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-26 09:56:10","ADY":284,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-34","SUBJID":"id-34","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.61602,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-17 09:56:10","TRTEDTM":"2022-07-17 03:56:10","TRT01SDTM":"2019-07-17 09:56:10","TRT01EDTM":"2021-07-16 21:56:10","TRT02SDTM":"2021-07-16 21:56:10","TRT02EDTM":"2022-07-17 03:56:10","AP01SDTM":"2019-07-17 09:56:10","AP01EDTM":"2021-07-16 21:56:10","AP02SDTM":"2021-07-16 21:56:10","AP02EDTM":"2022-07-17 03:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-28","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4006,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.71263,"AVALU":"mg/L","BASE2":8.06635,"BASE":8.74266,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.35372,"PCHG2":-4.38513,"CHG":-1.03003,"PCHG":-11.78168,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-09-08 09:56:10","ADY":419,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-34","SUBJID":"id-34","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.61602,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-17 09:56:10","TRTEDTM":"2022-07-17 03:56:10","TRT01SDTM":"2019-07-17 09:56:10","TRT01EDTM":"2021-07-16 21:56:10","TRT02SDTM":"2021-07-16 21:56:10","TRT02EDTM":"2022-07-17 03:56:10","AP01SDTM":"2019-07-17 09:56:10","AP01EDTM":"2021-07-16 21:56:10","AP02SDTM":"2021-07-16 21:56:10","AP02EDTM":"2022-07-17 03:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-28","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4976,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.81911,"AVALU":"mg/L","BASE2":8.06635,"BASE":8.74266,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.75276,"PCHG2":34.12641,"CHG":2.07644,"PCHG":23.75069,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-10-16 09:56:10","ADY":457,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-34","SUBJID":"id-34","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.61602,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-17 09:56:10","TRTEDTM":"2022-07-17 03:56:10","TRT01SDTM":"2019-07-17 09:56:10","TRT01EDTM":"2021-07-16 21:56:10","TRT02SDTM":"2021-07-16 21:56:10","TRT02EDTM":"2022-07-17 03:56:10","AP01SDTM":"2019-07-17 09:56:10","AP01EDTM":"2021-07-16 21:56:10","AP02SDTM":"2021-07-16 21:56:10","AP02EDTM":"2022-07-17 03:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-28","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1234,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.95168,"AVALU":"mg/L","BASE2":8.06635,"BASE":8.74266,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11467,"PCHG2":-1.42155,"CHG":-0.79098,"PCHG":-9.04735,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-12-19 09:56:10","ADY":521,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-34","SUBJID":"id-34","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.61602,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-17 09:56:10","TRTEDTM":"2022-07-17 03:56:10","TRT01SDTM":"2019-07-17 09:56:10","TRT01EDTM":"2021-07-16 21:56:10","TRT02SDTM":"2021-07-16 21:56:10","TRT02EDTM":"2022-07-17 03:56:10","AP01SDTM":"2019-07-17 09:56:10","AP01EDTM":"2021-07-16 21:56:10","AP02SDTM":"2021-07-16 21:56:10","AP02EDTM":"2022-07-17 03:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-28","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5192,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.22304,"AVALU":"mg/L","BASE2":8.06635,"BASE":8.74266,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.15669,"PCHG2":26.73689,"CHG":1.48038,"PCHG":16.93281,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-07-25 09:56:10","ADY":739,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-34","SUBJID":"id-34","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.61602,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-17 09:56:10","TRTEDTM":"2022-07-17 03:56:10","TRT01SDTM":"2019-07-17 09:56:10","TRT01EDTM":"2021-07-16 21:56:10","TRT02SDTM":"2021-07-16 21:56:10","TRT02EDTM":"2022-07-17 03:56:10","AP01SDTM":"2019-07-17 09:56:10","AP01EDTM":"2021-07-16 21:56:10","AP02SDTM":"2021-07-16 21:56:10","AP02EDTM":"2022-07-17 03:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-28","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6242,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.08581,"AVALU":"mg/L","BASE2":8.06635,"BASE":8.74266,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.01946,"PCHG2":12.63846,"CHG":0.34315,"PCHG":3.925,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-27 09:56:10","ADY":925,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-34","SUBJID":"id-34","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.61602,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-17 09:56:10","TRTEDTM":"2022-07-17 03:56:10","TRT01SDTM":"2019-07-17 09:56:10","TRT01EDTM":"2021-07-16 21:56:10","TRT02SDTM":"2021-07-16 21:56:10","TRT02EDTM":"2022-07-17 03:56:10","AP01SDTM":"2019-07-17 09:56:10","AP01EDTM":"2021-07-16 21:56:10","AP02SDTM":"2021-07-16 21:56:10","AP02EDTM":"2022-07-17 03:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-28","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7261,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90065,"AVALU":"g/L","BASE2":2.90065,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-26 09:56:10","ADY":71,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-34","SUBJID":"id-34","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.61602,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-17 09:56:10","TRTEDTM":"2022-07-17 03:56:10","TRT01SDTM":"2019-07-17 09:56:10","TRT01EDTM":"2021-07-16 21:56:10","TRT02SDTM":"2021-07-16 21:56:10","TRT02EDTM":"2022-07-17 03:56:10","AP01SDTM":"2019-07-17 09:56:10","AP01EDTM":"2021-07-16 21:56:10","AP02SDTM":"2021-07-16 21:56:10","AP02EDTM":"2022-07-17 03:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-28","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":975,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86148,"AVALU":"g/L","BASE2":2.90065,"BASE":2.86148,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.03917,"PCHG2":-1.35042,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-26 09:56:10","ADY":284,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-34","SUBJID":"id-34","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.61602,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-17 09:56:10","TRTEDTM":"2022-07-17 03:56:10","TRT01SDTM":"2019-07-17 09:56:10","TRT01EDTM":"2021-07-16 21:56:10","TRT02SDTM":"2021-07-16 21:56:10","TRT02EDTM":"2022-07-17 03:56:10","AP01SDTM":"2019-07-17 09:56:10","AP01EDTM":"2021-07-16 21:56:10","AP02SDTM":"2021-07-16 21:56:10","AP02EDTM":"2022-07-17 03:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-28","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7758,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97621,"AVALU":"g/L","BASE2":2.90065,"BASE":2.86148,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07555,"PCHG2":2.60462,"CHG":0.11472,"PCHG":4.00918,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-08 09:56:10","ADY":419,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-34","SUBJID":"id-34","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.61602,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-17 09:56:10","TRTEDTM":"2022-07-17 03:56:10","TRT01SDTM":"2019-07-17 09:56:10","TRT01EDTM":"2021-07-16 21:56:10","TRT02SDTM":"2021-07-16 21:56:10","TRT02EDTM":"2022-07-17 03:56:10","AP01SDTM":"2019-07-17 09:56:10","AP01EDTM":"2021-07-16 21:56:10","AP02SDTM":"2021-07-16 21:56:10","AP02EDTM":"2022-07-17 03:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-28","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6489,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9458,"AVALU":"g/L","BASE2":2.90065,"BASE":2.86148,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04515,"PCHG2":1.55638,"CHG":0.08432,"PCHG":2.94659,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-16 09:56:10","ADY":457,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-34","SUBJID":"id-34","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.61602,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-17 09:56:10","TRTEDTM":"2022-07-17 03:56:10","TRT01SDTM":"2019-07-17 09:56:10","TRT01EDTM":"2021-07-16 21:56:10","TRT02SDTM":"2021-07-16 21:56:10","TRT02EDTM":"2022-07-17 03:56:10","AP01SDTM":"2019-07-17 09:56:10","AP01EDTM":"2021-07-16 21:56:10","AP02SDTM":"2021-07-16 21:56:10","AP02EDTM":"2022-07-17 03:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-28","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7429,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91626,"AVALU":"g/L","BASE2":2.90065,"BASE":2.86148,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01561,"PCHG2":0.53803,"CHG":0.05478,"PCHG":1.91431,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-19 09:56:10","ADY":521,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-34","SUBJID":"id-34","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.61602,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-17 09:56:10","TRTEDTM":"2022-07-17 03:56:10","TRT01SDTM":"2019-07-17 09:56:10","TRT01EDTM":"2021-07-16 21:56:10","TRT02SDTM":"2021-07-16 21:56:10","TRT02EDTM":"2022-07-17 03:56:10","AP01SDTM":"2019-07-17 09:56:10","AP01EDTM":"2021-07-16 21:56:10","AP02SDTM":"2021-07-16 21:56:10","AP02EDTM":"2022-07-17 03:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-28","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3321,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88289,"AVALU":"g/L","BASE2":2.90065,"BASE":2.86148,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01776,"PCHG2":-0.6123,"CHG":0.02141,"PCHG":0.74823,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-25 09:56:10","ADY":739,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-34","SUBJID":"id-34","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.61602,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-17 09:56:10","TRTEDTM":"2022-07-17 03:56:10","TRT01SDTM":"2019-07-17 09:56:10","TRT01EDTM":"2021-07-16 21:56:10","TRT02SDTM":"2021-07-16 21:56:10","TRT02EDTM":"2022-07-17 03:56:10","AP01SDTM":"2019-07-17 09:56:10","AP01EDTM":"2021-07-16 21:56:10","AP02SDTM":"2021-07-16 21:56:10","AP02EDTM":"2022-07-17 03:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-28","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4939,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95323,"AVALU":"g/L","BASE2":2.90065,"BASE":2.86148,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05257,"PCHG2":1.81242,"CHG":0.09174,"PCHG":3.20614,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-27 09:56:10","ADY":925,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-342","SUBJID":"id-342","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.05374,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-02","TRTSDTM":"2020-05-04 23:38:32","TRTEDTM":"2023-05-05 17:38:32","TRT01SDTM":"2020-05-04 23:38:32","TRT01EDTM":"2022-05-05 11:38:32","TRT02SDTM":"2022-05-05 11:38:32","TRT02EDTM":"2023-05-05 17:38:32","AP01SDTM":"2020-05-04 23:38:32","AP01EDTM":"2022-05-05 11:38:32","AP02SDTM":"2022-05-05 11:38:32","AP02EDTM":"2023-05-05 17:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-27","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6283,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.55209,"AVALU":"U/L","BASE2":12.55209,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-27 23:38:32","ADY":299,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-342","SUBJID":"id-342","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.05374,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-02","TRTSDTM":"2020-05-04 23:38:32","TRTEDTM":"2023-05-05 17:38:32","TRT01SDTM":"2020-05-04 23:38:32","TRT01EDTM":"2022-05-05 11:38:32","TRT02SDTM":"2022-05-05 11:38:32","TRT02EDTM":"2023-05-05 17:38:32","AP01SDTM":"2020-05-04 23:38:32","AP01EDTM":"2022-05-05 11:38:32","AP02SDTM":"2022-05-05 11:38:32","AP02EDTM":"2023-05-05 17:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-27","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2208,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.0638,"AVALU":"U/L","BASE2":12.55209,"BASE":27.0638,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":14.5117,"PCHG2":115.61184,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-23 23:38:32","ADY":476,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-342","SUBJID":"id-342","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.05374,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-02","TRTSDTM":"2020-05-04 23:38:32","TRTEDTM":"2023-05-05 17:38:32","TRT01SDTM":"2020-05-04 23:38:32","TRT01EDTM":"2022-05-05 11:38:32","TRT02SDTM":"2022-05-05 11:38:32","TRT02EDTM":"2023-05-05 17:38:32","AP01SDTM":"2020-05-04 23:38:32","AP01EDTM":"2022-05-05 11:38:32","AP02SDTM":"2022-05-05 11:38:32","AP02EDTM":"2023-05-05 17:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-27","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5763,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.24976,"AVALU":"U/L","BASE2":12.55209,"BASE":27.0638,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.69766,"PCHG2":133.02693,"CHG":2.18596,"PCHG":8.07706,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-21 23:38:32","ADY":627,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-342","SUBJID":"id-342","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.05374,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-02","TRTSDTM":"2020-05-04 23:38:32","TRTEDTM":"2023-05-05 17:38:32","TRT01SDTM":"2020-05-04 23:38:32","TRT01EDTM":"2022-05-05 11:38:32","TRT02SDTM":"2022-05-05 11:38:32","TRT02EDTM":"2023-05-05 17:38:32","AP01SDTM":"2020-05-04 23:38:32","AP01EDTM":"2022-05-05 11:38:32","AP02SDTM":"2022-05-05 11:38:32","AP02EDTM":"2023-05-05 17:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-27","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7921,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.83119,"AVALU":"U/L","BASE2":12.55209,"BASE":27.0638,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.7209,"PCHG2":-37.61047,"CHG":-19.23261,"PCHG":-71.06396,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-25 23:38:32","ADY":631,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-342","SUBJID":"id-342","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.05374,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-02","TRTSDTM":"2020-05-04 23:38:32","TRTEDTM":"2023-05-05 17:38:32","TRT01SDTM":"2020-05-04 23:38:32","TRT01EDTM":"2022-05-05 11:38:32","TRT02SDTM":"2022-05-05 11:38:32","TRT02EDTM":"2023-05-05 17:38:32","AP01SDTM":"2020-05-04 23:38:32","AP01EDTM":"2022-05-05 11:38:32","AP02SDTM":"2022-05-05 11:38:32","AP02EDTM":"2023-05-05 17:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-27","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3378,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.4096,"AVALU":"U/L","BASE2":12.55209,"BASE":27.0638,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.14249,"PCHG2":-25.0356,"CHG":-17.6542,"PCHG":-65.23178,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-31 23:38:32","ADY":637,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-342","SUBJID":"id-342","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.05374,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-02","TRTSDTM":"2020-05-04 23:38:32","TRTEDTM":"2023-05-05 17:38:32","TRT01SDTM":"2020-05-04 23:38:32","TRT01EDTM":"2022-05-05 11:38:32","TRT02SDTM":"2022-05-05 11:38:32","TRT02EDTM":"2023-05-05 17:38:32","AP01SDTM":"2020-05-04 23:38:32","AP01EDTM":"2022-05-05 11:38:32","AP02SDTM":"2022-05-05 11:38:32","AP02EDTM":"2023-05-05 17:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-27","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3013,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.05437,"AVALU":"U/L","BASE2":12.55209,"BASE":27.0638,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.50227,"PCHG2":11.9683,"CHG":-13.00943,"PCHG":-48.0695,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-11 23:38:32","ADY":676,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-342","SUBJID":"id-342","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.05374,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-02","TRTSDTM":"2020-05-04 23:38:32","TRTEDTM":"2023-05-05 17:38:32","TRT01SDTM":"2020-05-04 23:38:32","TRT01EDTM":"2022-05-05 11:38:32","TRT02SDTM":"2022-05-05 11:38:32","TRT02EDTM":"2023-05-05 17:38:32","AP01SDTM":"2020-05-04 23:38:32","AP01EDTM":"2022-05-05 11:38:32","AP02SDTM":"2022-05-05 11:38:32","AP02EDTM":"2023-05-05 17:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-27","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8191,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.60228,"AVALU":"U/L","BASE2":12.55209,"BASE":27.0638,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.05019,"PCHG2":72.10101,"CHG":-5.46152,"PCHG":-20.18017,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-05 23:38:32","ADY":762,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-342","SUBJID":"id-342","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.05374,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-02","TRTSDTM":"2020-05-04 23:38:32","TRTEDTM":"2023-05-05 17:38:32","TRT01SDTM":"2020-05-04 23:38:32","TRT01EDTM":"2022-05-05 11:38:32","TRT02SDTM":"2022-05-05 11:38:32","TRT02EDTM":"2023-05-05 17:38:32","AP01SDTM":"2020-05-04 23:38:32","AP01EDTM":"2022-05-05 11:38:32","AP02SDTM":"2022-05-05 11:38:32","AP02EDTM":"2023-05-05 17:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-27","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7117,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.04814,"AVALU":"mg/L","BASE2":10.04814,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-02-27 23:38:32","ADY":299,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-342","SUBJID":"id-342","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.05374,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-02","TRTSDTM":"2020-05-04 23:38:32","TRTEDTM":"2023-05-05 17:38:32","TRT01SDTM":"2020-05-04 23:38:32","TRT01EDTM":"2022-05-05 11:38:32","TRT02SDTM":"2022-05-05 11:38:32","TRT02EDTM":"2023-05-05 17:38:32","AP01SDTM":"2020-05-04 23:38:32","AP01EDTM":"2022-05-05 11:38:32","AP02SDTM":"2022-05-05 11:38:32","AP02EDTM":"2023-05-05 17:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-27","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3274,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.34708,"AVALU":"mg/L","BASE2":10.04814,"BASE":9.34708,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.70106,"PCHG2":-6.977,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-23 23:38:32","ADY":476,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-342","SUBJID":"id-342","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.05374,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-02","TRTSDTM":"2020-05-04 23:38:32","TRTEDTM":"2023-05-05 17:38:32","TRT01SDTM":"2020-05-04 23:38:32","TRT01EDTM":"2022-05-05 11:38:32","TRT02SDTM":"2022-05-05 11:38:32","TRT02EDTM":"2023-05-05 17:38:32","AP01SDTM":"2020-05-04 23:38:32","AP01EDTM":"2022-05-05 11:38:32","AP02SDTM":"2022-05-05 11:38:32","AP02EDTM":"2023-05-05 17:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-27","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6167,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.69412,"AVALU":"mg/L","BASE2":10.04814,"BASE":9.34708,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.35402,"PCHG2":-23.42744,"CHG":-1.65296,"PCHG":-17.68428,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2022-01-21 23:38:32","ADY":627,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-342","SUBJID":"id-342","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.05374,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-02","TRTSDTM":"2020-05-04 23:38:32","TRTEDTM":"2023-05-05 17:38:32","TRT01SDTM":"2020-05-04 23:38:32","TRT01EDTM":"2022-05-05 11:38:32","TRT02SDTM":"2022-05-05 11:38:32","TRT02EDTM":"2023-05-05 17:38:32","AP01SDTM":"2020-05-04 23:38:32","AP01EDTM":"2022-05-05 11:38:32","AP02SDTM":"2022-05-05 11:38:32","AP02EDTM":"2023-05-05 17:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-27","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6468,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.02776,"AVALU":"mg/L","BASE2":10.04814,"BASE":9.34708,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.02038,"PCHG2":-20.10696,"CHG":-1.31932,"PCHG":-14.11475,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-25 23:38:32","ADY":631,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-342","SUBJID":"id-342","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.05374,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-02","TRTSDTM":"2020-05-04 23:38:32","TRTEDTM":"2023-05-05 17:38:32","TRT01SDTM":"2020-05-04 23:38:32","TRT01EDTM":"2022-05-05 11:38:32","TRT02SDTM":"2022-05-05 11:38:32","TRT02EDTM":"2023-05-05 17:38:32","AP01SDTM":"2020-05-04 23:38:32","AP01EDTM":"2022-05-05 11:38:32","AP02SDTM":"2022-05-05 11:38:32","AP02EDTM":"2023-05-05 17:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-27","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7502,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.88672,"AVALU":"mg/L","BASE2":10.04814,"BASE":9.34708,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16142,"PCHG2":-1.6065,"CHG":0.53964,"PCHG":5.7733,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-31 23:38:32","ADY":637,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-342","SUBJID":"id-342","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.05374,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-02","TRTSDTM":"2020-05-04 23:38:32","TRTEDTM":"2023-05-05 17:38:32","TRT01SDTM":"2020-05-04 23:38:32","TRT01EDTM":"2022-05-05 11:38:32","TRT02SDTM":"2022-05-05 11:38:32","TRT02EDTM":"2023-05-05 17:38:32","AP01SDTM":"2020-05-04 23:38:32","AP01EDTM":"2022-05-05 11:38:32","AP02SDTM":"2022-05-05 11:38:32","AP02EDTM":"2023-05-05 17:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-27","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6263,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.95885,"AVALU":"mg/L","BASE2":10.04814,"BASE":9.34708,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.08928,"PCHG2":-20.79275,"CHG":-1.38823,"PCHG":-14.85197,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-03-11 23:38:32","ADY":676,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-342","SUBJID":"id-342","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.05374,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-02","TRTSDTM":"2020-05-04 23:38:32","TRTEDTM":"2023-05-05 17:38:32","TRT01SDTM":"2020-05-04 23:38:32","TRT01EDTM":"2022-05-05 11:38:32","TRT02SDTM":"2022-05-05 11:38:32","TRT02EDTM":"2023-05-05 17:38:32","AP01SDTM":"2020-05-04 23:38:32","AP01EDTM":"2022-05-05 11:38:32","AP02SDTM":"2022-05-05 11:38:32","AP02EDTM":"2023-05-05 17:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-27","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5244,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.37294,"AVALU":"mg/L","BASE2":10.04814,"BASE":9.34708,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.6752,"PCHG2":-16.67177,"CHG":-0.97414,"PCHG":-10.42191,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-05 23:38:32","ADY":762,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-342","SUBJID":"id-342","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.05374,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-02","TRTSDTM":"2020-05-04 23:38:32","TRTEDTM":"2023-05-05 17:38:32","TRT01SDTM":"2020-05-04 23:38:32","TRT01EDTM":"2022-05-05 11:38:32","TRT02SDTM":"2022-05-05 11:38:32","TRT02EDTM":"2023-05-05 17:38:32","AP01SDTM":"2020-05-04 23:38:32","AP01EDTM":"2022-05-05 11:38:32","AP02SDTM":"2022-05-05 11:38:32","AP02EDTM":"2023-05-05 17:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-27","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3449,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.68041,"AVALU":"g/L","BASE2":2.68041,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-27 23:38:32","ADY":299,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-342","SUBJID":"id-342","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.05374,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-02","TRTSDTM":"2020-05-04 23:38:32","TRTEDTM":"2023-05-05 17:38:32","TRT01SDTM":"2020-05-04 23:38:32","TRT01EDTM":"2022-05-05 11:38:32","TRT02SDTM":"2022-05-05 11:38:32","TRT02EDTM":"2023-05-05 17:38:32","AP01SDTM":"2020-05-04 23:38:32","AP01EDTM":"2022-05-05 11:38:32","AP02SDTM":"2022-05-05 11:38:32","AP02EDTM":"2023-05-05 17:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-27","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7100,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9373,"AVALU":"g/L","BASE2":2.68041,"BASE":2.9373,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.25689,"PCHG2":9.58415,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-23 23:38:32","ADY":476,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-342","SUBJID":"id-342","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.05374,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-02","TRTSDTM":"2020-05-04 23:38:32","TRTEDTM":"2023-05-05 17:38:32","TRT01SDTM":"2020-05-04 23:38:32","TRT01EDTM":"2022-05-05 11:38:32","TRT02SDTM":"2022-05-05 11:38:32","TRT02EDTM":"2023-05-05 17:38:32","AP01SDTM":"2020-05-04 23:38:32","AP01EDTM":"2022-05-05 11:38:32","AP02SDTM":"2022-05-05 11:38:32","AP02EDTM":"2023-05-05 17:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-27","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":232,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88101,"AVALU":"g/L","BASE2":2.68041,"BASE":2.9373,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.2006,"PCHG2":7.48397,"CHG":-0.05629,"PCHG":-1.9165,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-21 23:38:32","ADY":627,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-342","SUBJID":"id-342","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.05374,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-02","TRTSDTM":"2020-05-04 23:38:32","TRTEDTM":"2023-05-05 17:38:32","TRT01SDTM":"2020-05-04 23:38:32","TRT01EDTM":"2022-05-05 11:38:32","TRT02SDTM":"2022-05-05 11:38:32","TRT02EDTM":"2023-05-05 17:38:32","AP01SDTM":"2020-05-04 23:38:32","AP01EDTM":"2022-05-05 11:38:32","AP02SDTM":"2022-05-05 11:38:32","AP02EDTM":"2023-05-05 17:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-27","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":489,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86103,"AVALU":"g/L","BASE2":2.68041,"BASE":2.9373,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18062,"PCHG2":6.73863,"CHG":-0.07627,"PCHG":-2.59665,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-25 23:38:32","ADY":631,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-342","SUBJID":"id-342","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.05374,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-02","TRTSDTM":"2020-05-04 23:38:32","TRTEDTM":"2023-05-05 17:38:32","TRT01SDTM":"2020-05-04 23:38:32","TRT01EDTM":"2022-05-05 11:38:32","TRT02SDTM":"2022-05-05 11:38:32","TRT02EDTM":"2023-05-05 17:38:32","AP01SDTM":"2020-05-04 23:38:32","AP01EDTM":"2022-05-05 11:38:32","AP02SDTM":"2022-05-05 11:38:32","AP02EDTM":"2023-05-05 17:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-27","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1959,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9347,"AVALU":"g/L","BASE2":2.68041,"BASE":2.9373,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.25429,"PCHG2":9.48701,"CHG":-0.0026,"PCHG":-0.08864,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-31 23:38:32","ADY":637,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-342","SUBJID":"id-342","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.05374,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-02","TRTSDTM":"2020-05-04 23:38:32","TRTEDTM":"2023-05-05 17:38:32","TRT01SDTM":"2020-05-04 23:38:32","TRT01EDTM":"2022-05-05 11:38:32","TRT02SDTM":"2022-05-05 11:38:32","TRT02EDTM":"2023-05-05 17:38:32","AP01SDTM":"2020-05-04 23:38:32","AP01EDTM":"2022-05-05 11:38:32","AP02SDTM":"2022-05-05 11:38:32","AP02EDTM":"2023-05-05 17:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-27","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3489,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05476,"AVALU":"g/L","BASE2":2.68041,"BASE":2.9373,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.37435,"PCHG2":13.96612,"CHG":0.11745,"PCHG":3.99873,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-03-11 23:38:32","ADY":676,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-342","SUBJID":"id-342","SITEID":"CHN-2","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":6.05374,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-02","TRTSDTM":"2020-05-04 23:38:32","TRTEDTM":"2023-05-05 17:38:32","TRT01SDTM":"2020-05-04 23:38:32","TRT01EDTM":"2022-05-05 11:38:32","TRT02SDTM":"2022-05-05 11:38:32","TRT02EDTM":"2023-05-05 17:38:32","AP01SDTM":"2020-05-04 23:38:32","AP01EDTM":"2022-05-05 11:38:32","AP02SDTM":"2022-05-05 11:38:32","AP02EDTM":"2023-05-05 17:38:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-05","EOSDY":1096,"LSTALVDT":"2023-05-27","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2290,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.73415,"AVALU":"g/L","BASE2":2.68041,"BASE":2.9373,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05374,"PCHG2":2.00487,"CHG":-0.20316,"PCHG":-6.9164,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-05 23:38:32","ADY":762,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-367","SUBJID":"id-367","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.81441,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-27 18:42:56","TRTEDTM":"2023-06-28 12:42:56","TRT01SDTM":"2020-06-27 18:42:56","TRT01EDTM":"2022-06-28 06:42:56","TRT02SDTM":"2022-06-28 06:42:56","TRT02EDTM":"2023-06-28 12:42:56","AP01SDTM":"2020-06-27 18:42:56","AP01EDTM":"2022-06-28 06:42:56","AP02SDTM":"2022-06-28 06:42:56","AP02EDTM":"2023-06-28 12:42:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-26","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6717,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.94379,"AVALU":"U/L","BASE2":21.94379,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-4","ADTM":"2020-08-12 18:42:56","ADY":46,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-367","SUBJID":"id-367","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.81441,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-27 18:42:56","TRTEDTM":"2023-06-28 12:42:56","TRT01SDTM":"2020-06-27 18:42:56","TRT01EDTM":"2022-06-28 06:42:56","TRT02SDTM":"2022-06-28 06:42:56","TRT02EDTM":"2023-06-28 12:42:56","AP01SDTM":"2020-06-27 18:42:56","AP01EDTM":"2022-06-28 06:42:56","AP02SDTM":"2022-06-28 06:42:56","AP02EDTM":"2023-06-28 12:42:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-26","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2529,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.9369,"AVALU":"U/L","BASE2":21.94379,"BASE":5.9369,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-16.00689,"PCHG2":-72.94496,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-4","BTOXGR":"-4","ADTM":"2021-02-02 18:42:56","ADY":220,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-367","SUBJID":"id-367","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.81441,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-27 18:42:56","TRTEDTM":"2023-06-28 12:42:56","TRT01SDTM":"2020-06-27 18:42:56","TRT01EDTM":"2022-06-28 06:42:56","TRT02SDTM":"2022-06-28 06:42:56","TRT02EDTM":"2023-06-28 12:42:56","AP01SDTM":"2020-06-27 18:42:56","AP01EDTM":"2022-06-28 06:42:56","AP02SDTM":"2022-06-28 06:42:56","AP02EDTM":"2023-06-28 12:42:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-26","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2568,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.78905,"AVALU":"U/L","BASE2":21.94379,"BASE":5.9369,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.15474,"PCHG2":-28.04777,"CHG":9.85215,"PCHG":165.94763,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-10-23 18:42:56","ADY":483,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-367","SUBJID":"id-367","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.81441,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-27 18:42:56","TRTEDTM":"2023-06-28 12:42:56","TRT01SDTM":"2020-06-27 18:42:56","TRT01EDTM":"2022-06-28 06:42:56","TRT02SDTM":"2022-06-28 06:42:56","TRT02EDTM":"2023-06-28 12:42:56","AP01SDTM":"2020-06-27 18:42:56","AP01EDTM":"2022-06-28 06:42:56","AP02SDTM":"2022-06-28 06:42:56","AP02EDTM":"2023-06-28 12:42:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-26","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2598,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.93217,"AVALU":"U/L","BASE2":21.94379,"BASE":5.9369,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.01162,"PCHG2":-9.16715,"CHG":13.99527,"PCHG":235.73359,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-12-26 18:42:56","ADY":547,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-367","SUBJID":"id-367","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.81441,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-27 18:42:56","TRTEDTM":"2023-06-28 12:42:56","TRT01SDTM":"2020-06-27 18:42:56","TRT01EDTM":"2022-06-28 06:42:56","TRT02SDTM":"2022-06-28 06:42:56","TRT02EDTM":"2023-06-28 12:42:56","AP01SDTM":"2020-06-27 18:42:56","AP01EDTM":"2022-06-28 06:42:56","AP02SDTM":"2022-06-28 06:42:56","AP02EDTM":"2023-06-28 12:42:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-26","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6667,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":37.17959,"AVALU":"U/L","BASE2":21.94379,"BASE":5.9369,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.2358,"PCHG2":69.43102,"CHG":31.24269,"PCHG":526.24569,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2022-01-07 18:42:56","ADY":559,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-367","SUBJID":"id-367","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.81441,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-27 18:42:56","TRTEDTM":"2023-06-28 12:42:56","TRT01SDTM":"2020-06-27 18:42:56","TRT01EDTM":"2022-06-28 06:42:56","TRT02SDTM":"2022-06-28 06:42:56","TRT02EDTM":"2023-06-28 12:42:56","AP01SDTM":"2020-06-27 18:42:56","AP01EDTM":"2022-06-28 06:42:56","AP02SDTM":"2022-06-28 06:42:56","AP02EDTM":"2023-06-28 12:42:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-26","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":710,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.38149,"AVALU":"U/L","BASE2":21.94379,"BASE":5.9369,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.5623,"PCHG2":-52.69055,"CHG":4.44459,"PCHG":74.86373,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2022-01-31 18:42:56","ADY":583,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-367","SUBJID":"id-367","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.81441,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-27 18:42:56","TRTEDTM":"2023-06-28 12:42:56","TRT01SDTM":"2020-06-27 18:42:56","TRT01EDTM":"2022-06-28 06:42:56","TRT02SDTM":"2022-06-28 06:42:56","TRT02EDTM":"2023-06-28 12:42:56","AP01SDTM":"2020-06-27 18:42:56","AP01EDTM":"2022-06-28 06:42:56","AP02SDTM":"2022-06-28 06:42:56","AP02EDTM":"2023-06-28 12:42:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-26","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1531,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.84555,"AVALU":"U/L","BASE2":21.94379,"BASE":5.9369,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.90176,"PCHG2":22.33778,"CHG":20.90865,"PCHG":352.18112,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2022-07-17 18:42:56","ADY":750,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-367","SUBJID":"id-367","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.81441,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-27 18:42:56","TRTEDTM":"2023-06-28 12:42:56","TRT01SDTM":"2020-06-27 18:42:56","TRT01EDTM":"2022-06-28 06:42:56","TRT02SDTM":"2022-06-28 06:42:56","TRT02EDTM":"2023-06-28 12:42:56","AP01SDTM":"2020-06-27 18:42:56","AP01EDTM":"2022-06-28 06:42:56","AP02SDTM":"2022-06-28 06:42:56","AP02EDTM":"2023-06-28 12:42:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-26","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3064,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.29009,"AVALU":"mg/L","BASE2":8.29009,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-12 18:42:56","ADY":46,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-367","SUBJID":"id-367","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.81441,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-27 18:42:56","TRTEDTM":"2023-06-28 12:42:56","TRT01SDTM":"2020-06-27 18:42:56","TRT01EDTM":"2022-06-28 06:42:56","TRT02SDTM":"2022-06-28 06:42:56","TRT02EDTM":"2023-06-28 12:42:56","AP01SDTM":"2020-06-27 18:42:56","AP01EDTM":"2022-06-28 06:42:56","AP02SDTM":"2022-06-28 06:42:56","AP02EDTM":"2023-06-28 12:42:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-26","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3916,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.16714,"AVALU":"mg/L","BASE2":8.29009,"BASE":8.16714,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.12295,"PCHG2":-1.48306,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-02 18:42:56","ADY":220,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-367","SUBJID":"id-367","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.81441,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-27 18:42:56","TRTEDTM":"2023-06-28 12:42:56","TRT01SDTM":"2020-06-27 18:42:56","TRT01EDTM":"2022-06-28 06:42:56","TRT02SDTM":"2022-06-28 06:42:56","TRT02EDTM":"2023-06-28 12:42:56","AP01SDTM":"2020-06-27 18:42:56","AP01EDTM":"2022-06-28 06:42:56","AP02SDTM":"2022-06-28 06:42:56","AP02EDTM":"2023-06-28 12:42:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-26","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5510,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.0379,"AVALU":"mg/L","BASE2":8.29009,"BASE":8.16714,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.7478,"PCHG2":21.08306,"CHG":1.87075,"PCHG":22.90583,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-10-23 18:42:56","ADY":483,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-367","SUBJID":"id-367","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.81441,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-27 18:42:56","TRTEDTM":"2023-06-28 12:42:56","TRT01SDTM":"2020-06-27 18:42:56","TRT01EDTM":"2022-06-28 06:42:56","TRT02SDTM":"2022-06-28 06:42:56","TRT02EDTM":"2023-06-28 12:42:56","AP01SDTM":"2020-06-27 18:42:56","AP01EDTM":"2022-06-28 06:42:56","AP02SDTM":"2022-06-28 06:42:56","AP02EDTM":"2023-06-28 12:42:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-26","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2505,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.38826,"AVALU":"mg/L","BASE2":8.29009,"BASE":8.16714,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.09817,"PCHG2":13.24682,"CHG":1.22112,"PCHG":14.95162,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-26 18:42:56","ADY":547,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-367","SUBJID":"id-367","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.81441,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-27 18:42:56","TRTEDTM":"2023-06-28 12:42:56","TRT01SDTM":"2020-06-27 18:42:56","TRT01EDTM":"2022-06-28 06:42:56","TRT02SDTM":"2022-06-28 06:42:56","TRT02EDTM":"2023-06-28 12:42:56","AP01SDTM":"2020-06-27 18:42:56","AP01EDTM":"2022-06-28 06:42:56","AP02SDTM":"2022-06-28 06:42:56","AP02EDTM":"2023-06-28 12:42:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-26","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5158,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.65573,"AVALU":"mg/L","BASE2":8.29009,"BASE":8.16714,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.36564,"PCHG2":4.41058,"CHG":0.48859,"PCHG":5.98236,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-07 18:42:56","ADY":559,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-367","SUBJID":"id-367","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.81441,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-27 18:42:56","TRTEDTM":"2023-06-28 12:42:56","TRT01SDTM":"2020-06-27 18:42:56","TRT01EDTM":"2022-06-28 06:42:56","TRT02SDTM":"2022-06-28 06:42:56","TRT02EDTM":"2023-06-28 12:42:56","AP01SDTM":"2020-06-27 18:42:56","AP01EDTM":"2022-06-28 06:42:56","AP02SDTM":"2022-06-28 06:42:56","AP02EDTM":"2023-06-28 12:42:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-26","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6085,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.26397,"AVALU":"mg/L","BASE2":8.29009,"BASE":8.16714,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02612,"PCHG2":-0.31503,"CHG":0.09683,"PCHG":1.18561,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-31 18:42:56","ADY":583,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-367","SUBJID":"id-367","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.81441,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-27 18:42:56","TRTEDTM":"2023-06-28 12:42:56","TRT01SDTM":"2020-06-27 18:42:56","TRT01EDTM":"2022-06-28 06:42:56","TRT02SDTM":"2022-06-28 06:42:56","TRT02EDTM":"2023-06-28 12:42:56","AP01SDTM":"2020-06-27 18:42:56","AP01EDTM":"2022-06-28 06:42:56","AP02SDTM":"2022-06-28 06:42:56","AP02EDTM":"2023-06-28 12:42:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-26","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1505,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.82812,"AVALU":"mg/L","BASE2":8.29009,"BASE":8.16714,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.53803,"PCHG2":6.49004,"CHG":0.66098,"PCHG":8.09312,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-17 18:42:56","ADY":750,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-367","SUBJID":"id-367","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.81441,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-27 18:42:56","TRTEDTM":"2023-06-28 12:42:56","TRT01SDTM":"2020-06-27 18:42:56","TRT01EDTM":"2022-06-28 06:42:56","TRT02SDTM":"2022-06-28 06:42:56","TRT02EDTM":"2023-06-28 12:42:56","AP01SDTM":"2020-06-27 18:42:56","AP01EDTM":"2022-06-28 06:42:56","AP02SDTM":"2022-06-28 06:42:56","AP02EDTM":"2023-06-28 12:42:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-26","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2292,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01152,"AVALU":"g/L","BASE2":3.01152,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-08-12 18:42:56","ADY":46,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-367","SUBJID":"id-367","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.81441,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-27 18:42:56","TRTEDTM":"2023-06-28 12:42:56","TRT01SDTM":"2020-06-27 18:42:56","TRT01EDTM":"2022-06-28 06:42:56","TRT02SDTM":"2022-06-28 06:42:56","TRT02EDTM":"2023-06-28 12:42:56","AP01SDTM":"2020-06-27 18:42:56","AP01EDTM":"2022-06-28 06:42:56","AP02SDTM":"2022-06-28 06:42:56","AP02EDTM":"2023-06-28 12:42:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-26","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6774,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88468,"AVALU":"g/L","BASE2":3.01152,"BASE":2.88468,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.12684,"PCHG2":-4.21175,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-02 18:42:56","ADY":220,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-367","SUBJID":"id-367","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.81441,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-27 18:42:56","TRTEDTM":"2023-06-28 12:42:56","TRT01SDTM":"2020-06-27 18:42:56","TRT01EDTM":"2022-06-28 06:42:56","TRT02SDTM":"2022-06-28 06:42:56","TRT02EDTM":"2023-06-28 12:42:56","AP01SDTM":"2020-06-27 18:42:56","AP01EDTM":"2022-06-28 06:42:56","AP02SDTM":"2022-06-28 06:42:56","AP02EDTM":"2023-06-28 12:42:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-26","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2962,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78871,"AVALU":"g/L","BASE2":3.01152,"BASE":2.88468,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.22281,"PCHG2":-7.39863,"CHG":-0.09597,"PCHG":-3.32701,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-23 18:42:56","ADY":483,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-367","SUBJID":"id-367","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.81441,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-27 18:42:56","TRTEDTM":"2023-06-28 12:42:56","TRT01SDTM":"2020-06-27 18:42:56","TRT01EDTM":"2022-06-28 06:42:56","TRT02SDTM":"2022-06-28 06:42:56","TRT02EDTM":"2023-06-28 12:42:56","AP01SDTM":"2020-06-27 18:42:56","AP01EDTM":"2022-06-28 06:42:56","AP02SDTM":"2022-06-28 06:42:56","AP02EDTM":"2023-06-28 12:42:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-26","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6310,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.67102,"AVALU":"g/L","BASE2":3.01152,"BASE":2.88468,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.3405,"PCHG2":-11.3067,"CHG":-0.21367,"PCHG":-7.40691,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-26 18:42:56","ADY":547,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-367","SUBJID":"id-367","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.81441,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-27 18:42:56","TRTEDTM":"2023-06-28 12:42:56","TRT01SDTM":"2020-06-27 18:42:56","TRT01EDTM":"2022-06-28 06:42:56","TRT02SDTM":"2022-06-28 06:42:56","TRT02EDTM":"2023-06-28 12:42:56","AP01SDTM":"2020-06-27 18:42:56","AP01EDTM":"2022-06-28 06:42:56","AP02SDTM":"2022-06-28 06:42:56","AP02EDTM":"2023-06-28 12:42:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-26","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4268,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0253,"AVALU":"g/L","BASE2":3.01152,"BASE":2.88468,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01378,"PCHG2":0.45758,"CHG":0.14062,"PCHG":4.87464,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-01-07 18:42:56","ADY":559,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-367","SUBJID":"id-367","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.81441,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-27 18:42:56","TRTEDTM":"2023-06-28 12:42:56","TRT01SDTM":"2020-06-27 18:42:56","TRT01EDTM":"2022-06-28 06:42:56","TRT02SDTM":"2022-06-28 06:42:56","TRT02EDTM":"2023-06-28 12:42:56","AP01SDTM":"2020-06-27 18:42:56","AP01EDTM":"2022-06-28 06:42:56","AP02SDTM":"2022-06-28 06:42:56","AP02EDTM":"2023-06-28 12:42:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-26","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3345,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03832,"AVALU":"g/L","BASE2":3.01152,"BASE":2.88468,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0268,"PCHG2":0.89,"CHG":0.15364,"PCHG":5.32607,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-01-31 18:42:56","ADY":583,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-367","SUBJID":"id-367","SITEID":"CHN-2","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.81441,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-06-24","TRTSDTM":"2020-06-27 18:42:56","TRTEDTM":"2023-06-28 12:42:56","TRT01SDTM":"2020-06-27 18:42:56","TRT01EDTM":"2022-06-28 06:42:56","TRT02SDTM":"2022-06-28 06:42:56","TRT02EDTM":"2023-06-28 12:42:56","AP01SDTM":"2020-06-27 18:42:56","AP01EDTM":"2022-06-28 06:42:56","AP02SDTM":"2022-06-28 06:42:56","AP02EDTM":"2023-06-28 12:42:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-28","EOSDY":1096,"LSTALVDT":"2023-07-26","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3229,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02268,"AVALU":"g/L","BASE2":3.01152,"BASE":2.88468,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01116,"PCHG2":0.37067,"CHG":0.138,"PCHG":4.78391,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-07-17 18:42:56","ADY":750,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-395","SUBJID":"id-395","SITEID":"CHN-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.4824,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 18:58:23","TRTEDTM":"2022-04-27 12:58:23","TRT01SDTM":"2019-04-27 18:58:23","TRT01EDTM":"2021-04-27 06:58:23","TRT02SDTM":"2021-04-27 06:58:23","TRT02EDTM":"2022-04-27 12:58:23","AP01SDTM":"2019-04-27 18:58:23","AP01EDTM":"2021-04-27 06:58:23","AP02SDTM":"2021-04-27 06:58:23","AP02EDTM":"2022-04-27 12:58:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7403,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.2185,"AVALU":"U/L","BASE2":13.2185,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-01 18:58:23","ADY":309,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-395","SUBJID":"id-395","SITEID":"CHN-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.4824,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 18:58:23","TRTEDTM":"2022-04-27 12:58:23","TRT01SDTM":"2019-04-27 18:58:23","TRT01EDTM":"2021-04-27 06:58:23","TRT02SDTM":"2021-04-27 06:58:23","TRT02EDTM":"2022-04-27 12:58:23","AP01SDTM":"2019-04-27 18:58:23","AP01EDTM":"2021-04-27 06:58:23","AP02SDTM":"2021-04-27 06:58:23","AP02EDTM":"2022-04-27 12:58:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4782,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":44.06444,"AVALU":"U/L","BASE2":13.2185,"BASE":44.06444,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":30.84595,"PCHG2":233.35436,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-03 18:58:23","ADY":495,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-395","SUBJID":"id-395","SITEID":"CHN-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.4824,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 18:58:23","TRTEDTM":"2022-04-27 12:58:23","TRT01SDTM":"2019-04-27 18:58:23","TRT01EDTM":"2021-04-27 06:58:23","TRT02SDTM":"2021-04-27 06:58:23","TRT02EDTM":"2022-04-27 12:58:23","AP01SDTM":"2019-04-27 18:58:23","AP01EDTM":"2021-04-27 06:58:23","AP02SDTM":"2021-04-27 06:58:23","AP02EDTM":"2022-04-27 12:58:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5106,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.87963,"AVALU":"U/L","BASE2":13.2185,"BASE":44.06444,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.66113,"PCHG2":5.00158,"CHG":-30.18481,"PCHG":-68.50151,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-22 18:58:23","ADY":514,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-395","SUBJID":"id-395","SITEID":"CHN-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.4824,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 18:58:23","TRTEDTM":"2022-04-27 12:58:23","TRT01SDTM":"2019-04-27 18:58:23","TRT01EDTM":"2021-04-27 06:58:23","TRT02SDTM":"2021-04-27 06:58:23","TRT02EDTM":"2022-04-27 12:58:23","AP01SDTM":"2019-04-27 18:58:23","AP01EDTM":"2021-04-27 06:58:23","AP02SDTM":"2021-04-27 06:58:23","AP02EDTM":"2022-04-27 12:58:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1967,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.07214,"AVALU":"U/L","BASE2":13.2185,"BASE":44.06444,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.85364,"PCHG2":6.45792,"CHG":-29.9923,"PCHG":-68.06464,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-02 18:58:23","ADY":920,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-395","SUBJID":"id-395","SITEID":"CHN-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.4824,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 18:58:23","TRTEDTM":"2022-04-27 12:58:23","TRT01SDTM":"2019-04-27 18:58:23","TRT01EDTM":"2021-04-27 06:58:23","TRT02SDTM":"2021-04-27 06:58:23","TRT02EDTM":"2022-04-27 12:58:23","AP01SDTM":"2019-04-27 18:58:23","AP01EDTM":"2021-04-27 06:58:23","AP02SDTM":"2021-04-27 06:58:23","AP02EDTM":"2022-04-27 12:58:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4034,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.97471,"AVALU":"U/L","BASE2":13.2185,"BASE":44.06444,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.24379,"PCHG2":-69.93073,"CHG":-40.08974,"PCHG":-90.97979,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-11-21 18:58:23","ADY":939,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-395","SUBJID":"id-395","SITEID":"CHN-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.4824,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 18:58:23","TRTEDTM":"2022-04-27 12:58:23","TRT01SDTM":"2019-04-27 18:58:23","TRT01EDTM":"2021-04-27 06:58:23","TRT02SDTM":"2021-04-27 06:58:23","TRT02EDTM":"2022-04-27 12:58:23","AP01SDTM":"2019-04-27 18:58:23","AP01EDTM":"2021-04-27 06:58:23","AP02SDTM":"2021-04-27 06:58:23","AP02EDTM":"2022-04-27 12:58:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1016,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.1343,"AVALU":"U/L","BASE2":13.2185,"BASE":44.06444,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.0842,"PCHG2":-15.7673,"CHG":-32.93015,"PCHG":-74.73178,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-25 18:58:23","ADY":1035,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-395","SUBJID":"id-395","SITEID":"CHN-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.4824,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 18:58:23","TRTEDTM":"2022-04-27 12:58:23","TRT01SDTM":"2019-04-27 18:58:23","TRT01EDTM":"2021-04-27 06:58:23","TRT02SDTM":"2021-04-27 06:58:23","TRT02EDTM":"2022-04-27 12:58:23","AP01SDTM":"2019-04-27 18:58:23","AP01EDTM":"2021-04-27 06:58:23","AP02SDTM":"2021-04-27 06:58:23","AP02EDTM":"2022-04-27 12:58:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1399,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.98821,"AVALU":"U/L","BASE2":13.2185,"BASE":44.06444,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.23029,"PCHG2":-69.82859,"CHG":-40.07624,"PCHG":-90.94915,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-03-20 18:58:23","ADY":1058,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-395","SUBJID":"id-395","SITEID":"CHN-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.4824,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 18:58:23","TRTEDTM":"2022-04-27 12:58:23","TRT01SDTM":"2019-04-27 18:58:23","TRT01EDTM":"2021-04-27 06:58:23","TRT02SDTM":"2021-04-27 06:58:23","TRT02EDTM":"2022-04-27 12:58:23","AP01SDTM":"2019-04-27 18:58:23","AP01EDTM":"2021-04-27 06:58:23","AP02SDTM":"2021-04-27 06:58:23","AP02EDTM":"2022-04-27 12:58:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1042,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.33299,"AVALU":"mg/L","BASE2":8.33299,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-01 18:58:23","ADY":309,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-395","SUBJID":"id-395","SITEID":"CHN-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.4824,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 18:58:23","TRTEDTM":"2022-04-27 12:58:23","TRT01SDTM":"2019-04-27 18:58:23","TRT01EDTM":"2021-04-27 06:58:23","TRT02SDTM":"2021-04-27 06:58:23","TRT02EDTM":"2022-04-27 12:58:23","AP01SDTM":"2019-04-27 18:58:23","AP01EDTM":"2021-04-27 06:58:23","AP02SDTM":"2021-04-27 06:58:23","AP02EDTM":"2022-04-27 12:58:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":897,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.80181,"AVALU":"mg/L","BASE2":8.33299,"BASE":9.80181,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.46882,"PCHG2":17.62656,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-03 18:58:23","ADY":495,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-395","SUBJID":"id-395","SITEID":"CHN-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.4824,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 18:58:23","TRTEDTM":"2022-04-27 12:58:23","TRT01SDTM":"2019-04-27 18:58:23","TRT01EDTM":"2021-04-27 06:58:23","TRT02SDTM":"2021-04-27 06:58:23","TRT02EDTM":"2022-04-27 12:58:23","AP01SDTM":"2019-04-27 18:58:23","AP01EDTM":"2021-04-27 06:58:23","AP02SDTM":"2021-04-27 06:58:23","AP02EDTM":"2022-04-27 12:58:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4688,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.37587,"AVALU":"mg/L","BASE2":8.33299,"BASE":9.80181,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04287,"PCHG2":0.5145,"CHG":-1.42595,"PCHG":-14.54778,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-22 18:58:23","ADY":514,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-395","SUBJID":"id-395","SITEID":"CHN-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.4824,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 18:58:23","TRTEDTM":"2022-04-27 12:58:23","TRT01SDTM":"2019-04-27 18:58:23","TRT01EDTM":"2021-04-27 06:58:23","TRT02SDTM":"2021-04-27 06:58:23","TRT02EDTM":"2022-04-27 12:58:23","AP01SDTM":"2019-04-27 18:58:23","AP01EDTM":"2021-04-27 06:58:23","AP02SDTM":"2021-04-27 06:58:23","AP02EDTM":"2022-04-27 12:58:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":23,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.79656,"AVALU":"mg/L","BASE2":8.33299,"BASE":9.80181,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.46357,"PCHG2":5.56304,"CHG":-1.00525,"PCHG":-10.25578,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-02 18:58:23","ADY":920,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-395","SUBJID":"id-395","SITEID":"CHN-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.4824,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 18:58:23","TRTEDTM":"2022-04-27 12:58:23","TRT01SDTM":"2019-04-27 18:58:23","TRT01EDTM":"2021-04-27 06:58:23","TRT02SDTM":"2021-04-27 06:58:23","TRT02EDTM":"2022-04-27 12:58:23","AP01SDTM":"2019-04-27 18:58:23","AP01EDTM":"2021-04-27 06:58:23","AP02SDTM":"2021-04-27 06:58:23","AP02EDTM":"2022-04-27 12:58:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3276,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.23528,"AVALU":"mg/L","BASE2":8.33299,"BASE":9.80181,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.90229,"PCHG2":10.8279,"CHG":-0.56653,"PCHG":-5.77987,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-21 18:58:23","ADY":939,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-395","SUBJID":"id-395","SITEID":"CHN-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.4824,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 18:58:23","TRTEDTM":"2022-04-27 12:58:23","TRT01SDTM":"2019-04-27 18:58:23","TRT01EDTM":"2021-04-27 06:58:23","TRT02SDTM":"2021-04-27 06:58:23","TRT02EDTM":"2022-04-27 12:58:23","AP01SDTM":"2019-04-27 18:58:23","AP01EDTM":"2021-04-27 06:58:23","AP02SDTM":"2021-04-27 06:58:23","AP02EDTM":"2022-04-27 12:58:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6008,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.45312,"AVALU":"mg/L","BASE2":8.33299,"BASE":9.80181,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.12013,"PCHG2":13.44213,"CHG":-0.34869,"PCHG":-3.55738,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-25 18:58:23","ADY":1035,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-395","SUBJID":"id-395","SITEID":"CHN-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.4824,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 18:58:23","TRTEDTM":"2022-04-27 12:58:23","TRT01SDTM":"2019-04-27 18:58:23","TRT01EDTM":"2021-04-27 06:58:23","TRT02SDTM":"2021-04-27 06:58:23","TRT02EDTM":"2022-04-27 12:58:23","AP01SDTM":"2019-04-27 18:58:23","AP01EDTM":"2021-04-27 06:58:23","AP02SDTM":"2021-04-27 06:58:23","AP02EDTM":"2022-04-27 12:58:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":459,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.66406,"AVALU":"mg/L","BASE2":8.33299,"BASE":9.80181,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.33107,"PCHG2":3.97299,"CHG":-1.13775,"PCHG":-11.60755,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-20 18:58:23","ADY":1058,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-395","SUBJID":"id-395","SITEID":"CHN-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.4824,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 18:58:23","TRTEDTM":"2022-04-27 12:58:23","TRT01SDTM":"2019-04-27 18:58:23","TRT01EDTM":"2021-04-27 06:58:23","TRT02SDTM":"2021-04-27 06:58:23","TRT02EDTM":"2022-04-27 12:58:23","AP01SDTM":"2019-04-27 18:58:23","AP01EDTM":"2021-04-27 06:58:23","AP02SDTM":"2021-04-27 06:58:23","AP02EDTM":"2022-04-27 12:58:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2851,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96176,"AVALU":"g/L","BASE2":2.96176,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-01 18:58:23","ADY":309,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-395","SUBJID":"id-395","SITEID":"CHN-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.4824,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 18:58:23","TRTEDTM":"2022-04-27 12:58:23","TRT01SDTM":"2019-04-27 18:58:23","TRT01EDTM":"2021-04-27 06:58:23","TRT02SDTM":"2021-04-27 06:58:23","TRT02EDTM":"2022-04-27 12:58:23","AP01SDTM":"2019-04-27 18:58:23","AP01EDTM":"2021-04-27 06:58:23","AP02SDTM":"2021-04-27 06:58:23","AP02EDTM":"2022-04-27 12:58:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4397,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94815,"AVALU":"g/L","BASE2":2.96176,"BASE":2.94815,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.01361,"PCHG2":-0.45949,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-03 18:58:23","ADY":495,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-395","SUBJID":"id-395","SITEID":"CHN-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.4824,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 18:58:23","TRTEDTM":"2022-04-27 12:58:23","TRT01SDTM":"2019-04-27 18:58:23","TRT01EDTM":"2021-04-27 06:58:23","TRT02SDTM":"2021-04-27 06:58:23","TRT02EDTM":"2022-04-27 12:58:23","AP01SDTM":"2019-04-27 18:58:23","AP01EDTM":"2021-04-27 06:58:23","AP02SDTM":"2021-04-27 06:58:23","AP02EDTM":"2022-04-27 12:58:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6902,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.875,"AVALU":"g/L","BASE2":2.96176,"BASE":2.94815,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08676,"PCHG2":-2.92949,"CHG":-0.07316,"PCHG":-2.4814,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-22 18:58:23","ADY":514,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-395","SUBJID":"id-395","SITEID":"CHN-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.4824,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 18:58:23","TRTEDTM":"2022-04-27 12:58:23","TRT01SDTM":"2019-04-27 18:58:23","TRT01EDTM":"2021-04-27 06:58:23","TRT02SDTM":"2021-04-27 06:58:23","TRT02EDTM":"2022-04-27 12:58:23","AP01SDTM":"2019-04-27 18:58:23","AP01EDTM":"2021-04-27 06:58:23","AP02SDTM":"2021-04-27 06:58:23","AP02EDTM":"2022-04-27 12:58:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7806,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92457,"AVALU":"g/L","BASE2":2.96176,"BASE":2.94815,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03719,"PCHG2":-1.25563,"CHG":-0.02358,"PCHG":-0.79982,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-02 18:58:23","ADY":920,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-395","SUBJID":"id-395","SITEID":"CHN-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.4824,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 18:58:23","TRTEDTM":"2022-04-27 12:58:23","TRT01SDTM":"2019-04-27 18:58:23","TRT01EDTM":"2021-04-27 06:58:23","TRT02SDTM":"2021-04-27 06:58:23","TRT02EDTM":"2022-04-27 12:58:23","AP01SDTM":"2019-04-27 18:58:23","AP01EDTM":"2021-04-27 06:58:23","AP02SDTM":"2021-04-27 06:58:23","AP02EDTM":"2022-04-27 12:58:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6926,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98391,"AVALU":"g/L","BASE2":2.96176,"BASE":2.94815,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02215,"PCHG2":0.74793,"CHG":0.03576,"PCHG":1.21299,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-21 18:58:23","ADY":939,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-395","SUBJID":"id-395","SITEID":"CHN-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.4824,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 18:58:23","TRTEDTM":"2022-04-27 12:58:23","TRT01SDTM":"2019-04-27 18:58:23","TRT01EDTM":"2021-04-27 06:58:23","TRT02SDTM":"2021-04-27 06:58:23","TRT02EDTM":"2022-04-27 12:58:23","AP01SDTM":"2019-04-27 18:58:23","AP01EDTM":"2021-04-27 06:58:23","AP02SDTM":"2021-04-27 06:58:23","AP02EDTM":"2022-04-27 12:58:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8375,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74684,"AVALU":"g/L","BASE2":2.96176,"BASE":2.94815,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21492,"PCHG2":-7.25647,"CHG":-0.20131,"PCHG":-6.82836,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-25 18:58:23","ADY":1035,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-395","SUBJID":"id-395","SITEID":"CHN-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.4824,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 18:58:23","TRTEDTM":"2022-04-27 12:58:23","TRT01SDTM":"2019-04-27 18:58:23","TRT01EDTM":"2021-04-27 06:58:23","TRT02SDTM":"2021-04-27 06:58:23","TRT02EDTM":"2022-04-27 12:58:23","AP01SDTM":"2019-04-27 18:58:23","AP01EDTM":"2021-04-27 06:58:23","AP02SDTM":"2021-04-27 06:58:23","AP02EDTM":"2022-04-27 12:58:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-16","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5254,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04057,"AVALU":"g/L","BASE2":2.96176,"BASE":2.94815,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07881,"PCHG2":2.66091,"CHG":0.09242,"PCHG":3.13481,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-03-20 18:58:23","ADY":1058,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-398","SUBJID":"id-398","SITEID":"CHN-2","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.3426,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-19 21:44:33","TRT01SDTM":"2019-10-19 21:44:33","AP01SDTM":"2019-10-19 21:44:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2714,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.1834,"AVALU":"U/L","BASE2":11.1834,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-04-03 21:44:33","ADY":167,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-398","SUBJID":"id-398","SITEID":"CHN-2","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.3426,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-19 21:44:33","TRT01SDTM":"2019-10-19 21:44:33","AP01SDTM":"2019-10-19 21:44:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7372,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.1222,"AVALU":"U/L","BASE2":11.1834,"BASE":0.1222,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-11.0612,"PCHG2":-98.90732,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2020-08-13 21:44:33","ADY":299,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-398","SUBJID":"id-398","SITEID":"CHN-2","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.3426,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-19 21:44:33","TRT01SDTM":"2019-10-19 21:44:33","AP01SDTM":"2019-10-19 21:44:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3334,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.10016,"AVALU":"U/L","BASE2":11.1834,"BASE":0.1222,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.91677,"PCHG2":8.19758,"CHG":11.97796,"PCHG":9802.04554,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-08-15 21:44:33","ADY":301,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-398","SUBJID":"id-398","SITEID":"CHN-2","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.3426,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-19 21:44:33","TRT01SDTM":"2019-10-19 21:44:33","AP01SDTM":"2019-10-19 21:44:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6802,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.58511,"AVALU":"U/L","BASE2":11.1834,"BASE":0.1222,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":22.40172,"PCHG2":200.31232,"CHG":33.46292,"PCHG":27384.03584,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-11-25 21:44:33","ADY":403,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-398","SUBJID":"id-398","SITEID":"CHN-2","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.3426,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-19 21:44:33","TRT01SDTM":"2019-10-19 21:44:33","AP01SDTM":"2019-10-19 21:44:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6622,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.52592,"AVALU":"U/L","BASE2":11.1834,"BASE":0.1222,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.34252,"PCHG2":119.30656,"CHG":24.40372,"PCHG":19970.536,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-01-03 21:44:33","ADY":442,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-398","SUBJID":"id-398","SITEID":"CHN-2","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.3426,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-19 21:44:33","TRT01SDTM":"2019-10-19 21:44:33","AP01SDTM":"2019-10-19 21:44:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7548,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.75894,"AVALU":"U/L","BASE2":11.1834,"BASE":0.1222,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.57555,"PCHG2":31.97195,"CHG":14.63675,"PCHG":11977.83221,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-03-21 21:44:33","ADY":519,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-398","SUBJID":"id-398","SITEID":"CHN-2","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.3426,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-19 21:44:33","TRT01SDTM":"2019-10-19 21:44:33","AP01SDTM":"2019-10-19 21:44:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4707,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.08264,"AVALU":"U/L","BASE2":11.1834,"BASE":0.1222,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10076,"PCHG2":-0.90098,"CHG":10.96044,"PCHG":8969.36187,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-07-07 21:44:33","ADY":627,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-398","SUBJID":"id-398","SITEID":"CHN-2","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.3426,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-19 21:44:33","TRT01SDTM":"2019-10-19 21:44:33","AP01SDTM":"2019-10-19 21:44:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7487,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.02556,"AVALU":"mg/L","BASE2":9.02556,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-03 21:44:33","ADY":167,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-398","SUBJID":"id-398","SITEID":"CHN-2","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.3426,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-19 21:44:33","TRT01SDTM":"2019-10-19 21:44:33","AP01SDTM":"2019-10-19 21:44:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7943,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.40306,"AVALU":"mg/L","BASE2":9.02556,"BASE":9.40306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.3775,"PCHG2":4.18251,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-13 21:44:33","ADY":299,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-398","SUBJID":"id-398","SITEID":"CHN-2","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.3426,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-19 21:44:33","TRT01SDTM":"2019-10-19 21:44:33","AP01SDTM":"2019-10-19 21:44:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7202,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.8671,"AVALU":"mg/L","BASE2":9.02556,"BASE":9.40306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.84154,"PCHG2":20.40362,"CHG":1.46405,"PCHG":15.5699,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-08-15 21:44:33","ADY":301,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-398","SUBJID":"id-398","SITEID":"CHN-2","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.3426,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-19 21:44:33","TRT01SDTM":"2019-10-19 21:44:33","AP01SDTM":"2019-10-19 21:44:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5055,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.15769,"AVALU":"mg/L","BASE2":9.02556,"BASE":9.40306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.86787,"PCHG2":-20.69532,"CHG":-2.24536,"PCHG":-23.87909,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-11-25 21:44:33","ADY":403,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-398","SUBJID":"id-398","SITEID":"CHN-2","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.3426,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-19 21:44:33","TRT01SDTM":"2019-10-19 21:44:33","AP01SDTM":"2019-10-19 21:44:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":306,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.02756,"AVALU":"mg/L","BASE2":9.02556,"BASE":9.40306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.002,"PCHG2":0.02217,"CHG":-0.37549,"PCHG":-3.99333,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-03 21:44:33","ADY":442,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-398","SUBJID":"id-398","SITEID":"CHN-2","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.3426,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-19 21:44:33","TRT01SDTM":"2019-10-19 21:44:33","AP01SDTM":"2019-10-19 21:44:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2479,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.56344,"AVALU":"mg/L","BASE2":9.02556,"BASE":9.40306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.53788,"PCHG2":5.95952,"CHG":0.16038,"PCHG":1.70566,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-21 21:44:33","ADY":519,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-398","SUBJID":"id-398","SITEID":"CHN-2","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.3426,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-19 21:44:33","TRT01SDTM":"2019-10-19 21:44:33","AP01SDTM":"2019-10-19 21:44:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1281,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.31753,"AVALU":"mg/L","BASE2":9.02556,"BASE":9.40306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.29197,"PCHG2":3.23491,"CHG":-0.08553,"PCHG":-0.90957,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-07 21:44:33","ADY":627,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-398","SUBJID":"id-398","SITEID":"CHN-2","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.3426,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-19 21:44:33","TRT01SDTM":"2019-10-19 21:44:33","AP01SDTM":"2019-10-19 21:44:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6381,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92471,"AVALU":"g/L","BASE2":2.92471,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-03 21:44:33","ADY":167,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-398","SUBJID":"id-398","SITEID":"CHN-2","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.3426,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-19 21:44:33","TRT01SDTM":"2019-10-19 21:44:33","AP01SDTM":"2019-10-19 21:44:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6234,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91903,"AVALU":"g/L","BASE2":2.92471,"BASE":2.91903,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.00568,"PCHG2":-0.19426,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-13 21:44:33","ADY":299,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-398","SUBJID":"id-398","SITEID":"CHN-2","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.3426,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-19 21:44:33","TRT01SDTM":"2019-10-19 21:44:33","AP01SDTM":"2019-10-19 21:44:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1785,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90968,"AVALU":"g/L","BASE2":2.92471,"BASE":2.91903,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01503,"PCHG2":-0.51383,"CHG":-0.00935,"PCHG":-0.32019,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-15 21:44:33","ADY":301,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-398","SUBJID":"id-398","SITEID":"CHN-2","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.3426,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-19 21:44:33","TRT01SDTM":"2019-10-19 21:44:33","AP01SDTM":"2019-10-19 21:44:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1881,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77331,"AVALU":"g/L","BASE2":2.92471,"BASE":2.91903,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1514,"PCHG2":-5.17649,"CHG":-0.14572,"PCHG":-4.99192,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-25 21:44:33","ADY":403,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-398","SUBJID":"id-398","SITEID":"CHN-2","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.3426,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-19 21:44:33","TRT01SDTM":"2019-10-19 21:44:33","AP01SDTM":"2019-10-19 21:44:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5506,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89557,"AVALU":"g/L","BASE2":2.92471,"BASE":2.91903,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02915,"PCHG2":-0.99655,"CHG":-0.02346,"PCHG":-0.80385,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-03 21:44:33","ADY":442,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-398","SUBJID":"id-398","SITEID":"CHN-2","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.3426,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-19 21:44:33","TRT01SDTM":"2019-10-19 21:44:33","AP01SDTM":"2019-10-19 21:44:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3221,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00762,"AVALU":"g/L","BASE2":2.92471,"BASE":2.91903,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08291,"PCHG2":2.83479,"CHG":0.08859,"PCHG":3.03495,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2021-03-21 21:44:33","ADY":519,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-398","SUBJID":"id-398","SITEID":"CHN-2","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.3426,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-19 21:44:33","TRT01SDTM":"2019-10-19 21:44:33","AP01SDTM":"2019-10-19 21:44:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6190,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94549,"AVALU":"g/L","BASE2":2.92471,"BASE":2.91903,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02078,"PCHG2":0.71055,"CHG":0.02646,"PCHG":0.90657,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-07 21:44:33","ADY":627,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-98","SUBJID":"id-98","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.0539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-27 03:36:25","TRTEDTM":"2023-03-27 21:36:25","TRT01SDTM":"2020-03-27 03:36:25","TRT01EDTM":"2022-03-27 15:36:25","TRT02SDTM":"2022-03-27 15:36:25","TRT02EDTM":"2023-03-27 21:36:25","AP01SDTM":"2020-03-27 03:36:25","AP01EDTM":"2022-03-27 15:36:25","AP02SDTM":"2022-03-27 15:36:25","AP02EDTM":"2023-03-27 21:36:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-27","EOSDY":1096,"LSTALVDT":"2023-04-10","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1972,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.94487,"AVALU":"U/L","BASE2":1.94487,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-09-19 03:36:25","ADY":176,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-98","SUBJID":"id-98","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.0539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-27 03:36:25","TRTEDTM":"2023-03-27 21:36:25","TRT01SDTM":"2020-03-27 03:36:25","TRT01EDTM":"2022-03-27 15:36:25","TRT02SDTM":"2022-03-27 15:36:25","TRT02EDTM":"2023-03-27 21:36:25","AP01SDTM":"2020-03-27 03:36:25","AP01EDTM":"2022-03-27 15:36:25","AP02SDTM":"2022-03-27 15:36:25","AP02EDTM":"2023-03-27 21:36:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-27","EOSDY":1096,"LSTALVDT":"2023-04-10","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2006,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.9295,"AVALU":"U/L","BASE2":1.94487,"BASE":19.9295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":17.98463,"PCHG2":924.72351,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-23 03:36:25","ADY":180,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-98","SUBJID":"id-98","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.0539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-27 03:36:25","TRTEDTM":"2023-03-27 21:36:25","TRT01SDTM":"2020-03-27 03:36:25","TRT01EDTM":"2022-03-27 15:36:25","TRT02SDTM":"2022-03-27 15:36:25","TRT02EDTM":"2023-03-27 21:36:25","AP01SDTM":"2020-03-27 03:36:25","AP01EDTM":"2022-03-27 15:36:25","AP02SDTM":"2022-03-27 15:36:25","AP02EDTM":"2023-03-27 21:36:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-27","EOSDY":1096,"LSTALVDT":"2023-04-10","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4168,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.8422,"AVALU":"U/L","BASE2":1.94487,"BASE":19.9295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.89734,"PCHG2":1023.06986,"CHG":1.9127,"PCHG":9.59735,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-20 03:36:25","ADY":695,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-98","SUBJID":"id-98","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.0539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-27 03:36:25","TRTEDTM":"2023-03-27 21:36:25","TRT01SDTM":"2020-03-27 03:36:25","TRT01EDTM":"2022-03-27 15:36:25","TRT02SDTM":"2022-03-27 15:36:25","TRT02EDTM":"2023-03-27 21:36:25","AP01SDTM":"2020-03-27 03:36:25","AP01EDTM":"2022-03-27 15:36:25","AP02SDTM":"2022-03-27 15:36:25","AP02EDTM":"2023-03-27 21:36:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-27","EOSDY":1096,"LSTALVDT":"2023-04-10","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6299,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.09207,"AVALU":"U/L","BASE2":1.94487,"BASE":19.9295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.1472,"PCHG2":933.0825,"CHG":0.16257,"PCHG":0.81573,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-30 03:36:25","ADY":794,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-98","SUBJID":"id-98","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.0539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-27 03:36:25","TRTEDTM":"2023-03-27 21:36:25","TRT01SDTM":"2020-03-27 03:36:25","TRT01EDTM":"2022-03-27 15:36:25","TRT02SDTM":"2022-03-27 15:36:25","TRT02EDTM":"2023-03-27 21:36:25","AP01SDTM":"2020-03-27 03:36:25","AP01EDTM":"2022-03-27 15:36:25","AP02SDTM":"2022-03-27 15:36:25","AP02EDTM":"2023-03-27 21:36:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-27","EOSDY":1096,"LSTALVDT":"2023-04-10","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5691,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.06699,"AVALU":"U/L","BASE2":1.94487,"BASE":19.9295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.12212,"PCHG2":211.94891,"CHG":-13.86251,"PCHG":-69.55775,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-08-01 03:36:25","ADY":857,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-98","SUBJID":"id-98","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.0539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-27 03:36:25","TRTEDTM":"2023-03-27 21:36:25","TRT01SDTM":"2020-03-27 03:36:25","TRT01EDTM":"2022-03-27 15:36:25","TRT02SDTM":"2022-03-27 15:36:25","TRT02EDTM":"2023-03-27 21:36:25","AP01SDTM":"2020-03-27 03:36:25","AP01EDTM":"2022-03-27 15:36:25","AP02SDTM":"2022-03-27 15:36:25","AP02EDTM":"2023-03-27 21:36:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-27","EOSDY":1096,"LSTALVDT":"2023-04-10","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4732,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.53889,"AVALU":"U/L","BASE2":1.94487,"BASE":19.9295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":23.59402,"PCHG2":1213.14386,"CHG":5.60939,"PCHG":28.14616,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-27 03:36:25","ADY":914,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-98","SUBJID":"id-98","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.0539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-27 03:36:25","TRTEDTM":"2023-03-27 21:36:25","TRT01SDTM":"2020-03-27 03:36:25","TRT01EDTM":"2022-03-27 15:36:25","TRT02SDTM":"2022-03-27 15:36:25","TRT02EDTM":"2023-03-27 21:36:25","AP01SDTM":"2020-03-27 03:36:25","AP01EDTM":"2022-03-27 15:36:25","AP02SDTM":"2022-03-27 15:36:25","AP02EDTM":"2023-03-27 21:36:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-27","EOSDY":1096,"LSTALVDT":"2023-04-10","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2508,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.62157,"AVALU":"U/L","BASE2":1.94487,"BASE":19.9295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.6767,"PCHG2":754.63838,"CHG":-3.30793,"PCHG":-16.59815,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-04 03:36:25","ADY":1044,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-98","SUBJID":"id-98","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.0539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-27 03:36:25","TRTEDTM":"2023-03-27 21:36:25","TRT01SDTM":"2020-03-27 03:36:25","TRT01EDTM":"2022-03-27 15:36:25","TRT02SDTM":"2022-03-27 15:36:25","TRT02EDTM":"2023-03-27 21:36:25","AP01SDTM":"2020-03-27 03:36:25","AP01EDTM":"2022-03-27 15:36:25","AP02SDTM":"2022-03-27 15:36:25","AP02EDTM":"2023-03-27 21:36:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-27","EOSDY":1096,"LSTALVDT":"2023-04-10","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1871,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.62891,"AVALU":"mg/L","BASE2":8.62891,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-09-19 03:36:25","ADY":176,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-98","SUBJID":"id-98","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.0539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-27 03:36:25","TRTEDTM":"2023-03-27 21:36:25","TRT01SDTM":"2020-03-27 03:36:25","TRT01EDTM":"2022-03-27 15:36:25","TRT02SDTM":"2022-03-27 15:36:25","TRT02EDTM":"2023-03-27 21:36:25","AP01SDTM":"2020-03-27 03:36:25","AP01EDTM":"2022-03-27 15:36:25","AP02SDTM":"2022-03-27 15:36:25","AP02EDTM":"2023-03-27 21:36:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-27","EOSDY":1096,"LSTALVDT":"2023-04-10","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3603,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.94162,"AVALU":"mg/L","BASE2":8.62891,"BASE":7.94162,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.68729,"PCHG2":-7.96498,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2020-09-23 03:36:25","ADY":180,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-98","SUBJID":"id-98","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.0539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-27 03:36:25","TRTEDTM":"2023-03-27 21:36:25","TRT01SDTM":"2020-03-27 03:36:25","TRT01EDTM":"2022-03-27 15:36:25","TRT02SDTM":"2022-03-27 15:36:25","TRT02EDTM":"2023-03-27 21:36:25","AP01SDTM":"2020-03-27 03:36:25","AP01EDTM":"2022-03-27 15:36:25","AP02SDTM":"2022-03-27 15:36:25","AP02EDTM":"2023-03-27 21:36:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-27","EOSDY":1096,"LSTALVDT":"2023-04-10","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3448,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.64604,"AVALU":"mg/L","BASE2":8.62891,"BASE":7.94162,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01713,"PCHG2":0.19854,"CHG":0.70442,"PCHG":8.87002,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-02-20 03:36:25","ADY":695,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-98","SUBJID":"id-98","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.0539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-27 03:36:25","TRTEDTM":"2023-03-27 21:36:25","TRT01SDTM":"2020-03-27 03:36:25","TRT01EDTM":"2022-03-27 15:36:25","TRT02SDTM":"2022-03-27 15:36:25","TRT02EDTM":"2023-03-27 21:36:25","AP01SDTM":"2020-03-27 03:36:25","AP01EDTM":"2022-03-27 15:36:25","AP02SDTM":"2022-03-27 15:36:25","AP02EDTM":"2023-03-27 21:36:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-27","EOSDY":1096,"LSTALVDT":"2023-04-10","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2524,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.09594,"AVALU":"mg/L","BASE2":8.62891,"BASE":7.94162,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.46702,"PCHG2":5.4123,"CHG":1.15431,"PCHG":14.535,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-05-30 03:36:25","ADY":794,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-98","SUBJID":"id-98","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.0539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-27 03:36:25","TRTEDTM":"2023-03-27 21:36:25","TRT01SDTM":"2020-03-27 03:36:25","TRT01EDTM":"2022-03-27 15:36:25","TRT02SDTM":"2022-03-27 15:36:25","TRT02EDTM":"2023-03-27 21:36:25","AP01SDTM":"2020-03-27 03:36:25","AP01EDTM":"2022-03-27 15:36:25","AP02SDTM":"2022-03-27 15:36:25","AP02EDTM":"2023-03-27 21:36:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-27","EOSDY":1096,"LSTALVDT":"2023-04-10","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":360,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.84149,"AVALU":"mg/L","BASE2":8.62891,"BASE":7.94162,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.21258,"PCHG2":25.64147,"CHG":2.89987,"PCHG":36.51486,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"4","BTOXGR":"-2","ADTM":"2022-08-01 03:36:25","ADY":857,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-98","SUBJID":"id-98","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.0539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-27 03:36:25","TRTEDTM":"2023-03-27 21:36:25","TRT01SDTM":"2020-03-27 03:36:25","TRT01EDTM":"2022-03-27 15:36:25","TRT02SDTM":"2022-03-27 15:36:25","TRT02EDTM":"2023-03-27 21:36:25","AP01SDTM":"2020-03-27 03:36:25","AP01EDTM":"2022-03-27 15:36:25","AP02SDTM":"2022-03-27 15:36:25","AP02EDTM":"2023-03-27 21:36:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-27","EOSDY":1096,"LSTALVDT":"2023-04-10","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":349,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.1843,"AVALU":"mg/L","BASE2":8.62891,"BASE":7.94162,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.44461,"PCHG2":-5.15255,"CHG":0.24268,"PCHG":3.05583,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-09-27 03:36:25","ADY":914,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-98","SUBJID":"id-98","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.0539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-27 03:36:25","TRTEDTM":"2023-03-27 21:36:25","TRT01SDTM":"2020-03-27 03:36:25","TRT01EDTM":"2022-03-27 15:36:25","TRT02SDTM":"2022-03-27 15:36:25","TRT02EDTM":"2023-03-27 21:36:25","AP01SDTM":"2020-03-27 03:36:25","AP01EDTM":"2022-03-27 15:36:25","AP02SDTM":"2022-03-27 15:36:25","AP02EDTM":"2023-03-27 21:36:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-27","EOSDY":1096,"LSTALVDT":"2023-04-10","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2333,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.14902,"AVALU":"mg/L","BASE2":8.62891,"BASE":7.94162,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.52011,"PCHG2":6.02751,"CHG":1.2074,"PCHG":15.20345,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2023-02-04 03:36:25","ADY":1044,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-98","SUBJID":"id-98","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.0539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-27 03:36:25","TRTEDTM":"2023-03-27 21:36:25","TRT01SDTM":"2020-03-27 03:36:25","TRT01EDTM":"2022-03-27 15:36:25","TRT02SDTM":"2022-03-27 15:36:25","TRT02EDTM":"2023-03-27 21:36:25","AP01SDTM":"2020-03-27 03:36:25","AP01EDTM":"2022-03-27 15:36:25","AP02SDTM":"2022-03-27 15:36:25","AP02EDTM":"2023-03-27 21:36:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-27","EOSDY":1096,"LSTALVDT":"2023-04-10","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7632,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8216,"AVALU":"g/L","BASE2":2.8216,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-19 03:36:25","ADY":176,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-98","SUBJID":"id-98","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.0539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-27 03:36:25","TRTEDTM":"2023-03-27 21:36:25","TRT01SDTM":"2020-03-27 03:36:25","TRT01EDTM":"2022-03-27 15:36:25","TRT02SDTM":"2022-03-27 15:36:25","TRT02EDTM":"2023-03-27 21:36:25","AP01SDTM":"2020-03-27 03:36:25","AP01EDTM":"2022-03-27 15:36:25","AP02SDTM":"2022-03-27 15:36:25","AP02EDTM":"2023-03-27 21:36:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-27","EOSDY":1096,"LSTALVDT":"2023-04-10","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":638,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88167,"AVALU":"g/L","BASE2":2.8216,"BASE":2.88167,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.06007,"PCHG2":2.12882,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-23 03:36:25","ADY":180,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-98","SUBJID":"id-98","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.0539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-27 03:36:25","TRTEDTM":"2023-03-27 21:36:25","TRT01SDTM":"2020-03-27 03:36:25","TRT01EDTM":"2022-03-27 15:36:25","TRT02SDTM":"2022-03-27 15:36:25","TRT02EDTM":"2023-03-27 21:36:25","AP01SDTM":"2020-03-27 03:36:25","AP01EDTM":"2022-03-27 15:36:25","AP02SDTM":"2022-03-27 15:36:25","AP02EDTM":"2023-03-27 21:36:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-27","EOSDY":1096,"LSTALVDT":"2023-04-10","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4693,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98118,"AVALU":"g/L","BASE2":2.8216,"BASE":2.88167,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15958,"PCHG2":5.65583,"CHG":0.09952,"PCHG":3.45349,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-20 03:36:25","ADY":695,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-98","SUBJID":"id-98","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.0539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-27 03:36:25","TRTEDTM":"2023-03-27 21:36:25","TRT01SDTM":"2020-03-27 03:36:25","TRT01EDTM":"2022-03-27 15:36:25","TRT02SDTM":"2022-03-27 15:36:25","TRT02EDTM":"2023-03-27 21:36:25","AP01SDTM":"2020-03-27 03:36:25","AP01EDTM":"2022-03-27 15:36:25","AP02SDTM":"2022-03-27 15:36:25","AP02EDTM":"2023-03-27 21:36:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-27","EOSDY":1096,"LSTALVDT":"2023-04-10","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1350,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.71165,"AVALU":"g/L","BASE2":2.8216,"BASE":2.88167,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10995,"PCHG2":-3.89668,"CHG":-0.17002,"PCHG":-5.8999,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-30 03:36:25","ADY":794,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-98","SUBJID":"id-98","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.0539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-27 03:36:25","TRTEDTM":"2023-03-27 21:36:25","TRT01SDTM":"2020-03-27 03:36:25","TRT01EDTM":"2022-03-27 15:36:25","TRT02SDTM":"2022-03-27 15:36:25","TRT02EDTM":"2023-03-27 21:36:25","AP01SDTM":"2020-03-27 03:36:25","AP01EDTM":"2022-03-27 15:36:25","AP02SDTM":"2022-03-27 15:36:25","AP02EDTM":"2023-03-27 21:36:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-27","EOSDY":1096,"LSTALVDT":"2023-04-10","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7524,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98658,"AVALU":"g/L","BASE2":2.8216,"BASE":2.88167,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16498,"PCHG2":5.84701,"CHG":0.10491,"PCHG":3.64069,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-01 03:36:25","ADY":857,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-98","SUBJID":"id-98","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.0539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-27 03:36:25","TRTEDTM":"2023-03-27 21:36:25","TRT01SDTM":"2020-03-27 03:36:25","TRT01EDTM":"2022-03-27 15:36:25","TRT02SDTM":"2022-03-27 15:36:25","TRT02EDTM":"2023-03-27 21:36:25","AP01SDTM":"2020-03-27 03:36:25","AP01EDTM":"2022-03-27 15:36:25","AP02SDTM":"2022-03-27 15:36:25","AP02EDTM":"2023-03-27 21:36:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-27","EOSDY":1096,"LSTALVDT":"2023-04-10","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6257,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82222,"AVALU":"g/L","BASE2":2.8216,"BASE":2.88167,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00062,"PCHG2":0.02208,"CHG":-0.05944,"PCHG":-2.06282,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-27 03:36:25","ADY":914,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-2-id-98","SUBJID":"id-98","SITEID":"CHN-2","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-2","INVNAM":"Dr. CHN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.0539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-27 03:36:25","TRTEDTM":"2023-03-27 21:36:25","TRT01SDTM":"2020-03-27 03:36:25","TRT01EDTM":"2022-03-27 15:36:25","TRT02SDTM":"2022-03-27 15:36:25","TRT02EDTM":"2023-03-27 21:36:25","AP01SDTM":"2020-03-27 03:36:25","AP01EDTM":"2022-03-27 15:36:25","AP02SDTM":"2022-03-27 15:36:25","AP02EDTM":"2023-03-27 21:36:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-27","EOSDY":1096,"LSTALVDT":"2023-04-10","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7801,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76152,"AVALU":"g/L","BASE2":2.8216,"BASE":2.88167,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06008,"PCHG2":-2.12936,"CHG":-0.12015,"PCHG":-4.16942,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-04 03:36:25","ADY":1044,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-128","SUBJID":"id-128","SITEID":"CHN-3","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":14.42493,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-22","TRTSDTM":"2019-02-24 11:09:25","TRTEDTM":"2022-02-12 04:28:08","TRT01SDTM":"2019-02-24 11:09:25","TRT01EDTM":"2021-02-11 22:28:08","TRT02SDTM":"2021-02-11 22:28:08","TRT02EDTM":"2022-02-12 04:28:08","AP01SDTM":"2019-02-24 11:09:25","AP01EDTM":"2021-02-11 22:28:08","AP02SDTM":"2021-02-11 22:28:08","AP02EDTM":"2022-02-12 04:28:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":1084,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":1105,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2232,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.73546,"AVALU":"U/L","BASE2":11.73546,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2019-06-16 11:09:25","ADY":112,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-128","SUBJID":"id-128","SITEID":"CHN-3","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":14.42493,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-22","TRTSDTM":"2019-02-24 11:09:25","TRTEDTM":"2022-02-12 04:28:08","TRT01SDTM":"2019-02-24 11:09:25","TRT01EDTM":"2021-02-11 22:28:08","TRT02SDTM":"2021-02-11 22:28:08","TRT02EDTM":"2022-02-12 04:28:08","AP01SDTM":"2019-02-24 11:09:25","AP01EDTM":"2021-02-11 22:28:08","AP02SDTM":"2021-02-11 22:28:08","AP02EDTM":"2022-02-12 04:28:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":1084,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":1105,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6369,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.42964,"AVALU":"U/L","BASE2":11.73546,"BASE":2.42964,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-9.30582,"PCHG2":-79.29657,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2019-07-25 11:09:25","ADY":151,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-128","SUBJID":"id-128","SITEID":"CHN-3","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":14.42493,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-22","TRTSDTM":"2019-02-24 11:09:25","TRTEDTM":"2022-02-12 04:28:08","TRT01SDTM":"2019-02-24 11:09:25","TRT01EDTM":"2021-02-11 22:28:08","TRT02SDTM":"2021-02-11 22:28:08","TRT02EDTM":"2022-02-12 04:28:08","AP01SDTM":"2019-02-24 11:09:25","AP01EDTM":"2021-02-11 22:28:08","AP02SDTM":"2021-02-11 22:28:08","AP02EDTM":"2022-02-12 04:28:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":1084,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":1105,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6457,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.25671,"AVALU":"U/L","BASE2":11.73546,"BASE":2.42964,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.52125,"PCHG2":21.48402,"CHG":11.82707,"PCHG":486.78223,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2019-10-20 11:09:25","ADY":238,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-128","SUBJID":"id-128","SITEID":"CHN-3","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":14.42493,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-22","TRTSDTM":"2019-02-24 11:09:25","TRTEDTM":"2022-02-12 04:28:08","TRT01SDTM":"2019-02-24 11:09:25","TRT01EDTM":"2021-02-11 22:28:08","TRT02SDTM":"2021-02-11 22:28:08","TRT02EDTM":"2022-02-12 04:28:08","AP01SDTM":"2019-02-24 11:09:25","AP01EDTM":"2021-02-11 22:28:08","AP02SDTM":"2021-02-11 22:28:08","AP02EDTM":"2022-02-12 04:28:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":1084,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":1105,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7853,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":35.29073,"AVALU":"U/L","BASE2":11.73546,"BASE":2.42964,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":23.55527,"PCHG2":200.7187,"CHG":32.86109,"PCHG":1352.507,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2019-10-24 11:09:25","ADY":242,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-128","SUBJID":"id-128","SITEID":"CHN-3","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":14.42493,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-22","TRTSDTM":"2019-02-24 11:09:25","TRTEDTM":"2022-02-12 04:28:08","TRT01SDTM":"2019-02-24 11:09:25","TRT01EDTM":"2021-02-11 22:28:08","TRT02SDTM":"2021-02-11 22:28:08","TRT02EDTM":"2022-02-12 04:28:08","AP01SDTM":"2019-02-24 11:09:25","AP01EDTM":"2021-02-11 22:28:08","AP02SDTM":"2021-02-11 22:28:08","AP02EDTM":"2022-02-12 04:28:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":1084,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":1105,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7805,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.5769,"AVALU":"U/L","BASE2":11.73546,"BASE":2.42964,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.15857,"PCHG2":-43.95707,"CHG":4.14725,"PCHG":170.69398,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-4","BTOXGR":"-2","ADTM":"2020-01-03 11:09:25","ADY":313,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-128","SUBJID":"id-128","SITEID":"CHN-3","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":14.42493,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-22","TRTSDTM":"2019-02-24 11:09:25","TRTEDTM":"2022-02-12 04:28:08","TRT01SDTM":"2019-02-24 11:09:25","TRT01EDTM":"2021-02-11 22:28:08","TRT02SDTM":"2021-02-11 22:28:08","TRT02EDTM":"2022-02-12 04:28:08","AP01SDTM":"2019-02-24 11:09:25","AP01EDTM":"2021-02-11 22:28:08","AP02SDTM":"2021-02-11 22:28:08","AP02EDTM":"2022-02-12 04:28:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":1084,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":1105,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1987,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.81173,"AVALU":"U/L","BASE2":11.73546,"BASE":2.42964,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07627,"PCHG2":0.64989,"CHG":9.38209,"PCHG":386.1509,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-03-23 11:09:25","ADY":393,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-128","SUBJID":"id-128","SITEID":"CHN-3","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":14.42493,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-22","TRTSDTM":"2019-02-24 11:09:25","TRTEDTM":"2022-02-12 04:28:08","TRT01SDTM":"2019-02-24 11:09:25","TRT01EDTM":"2021-02-11 22:28:08","TRT02SDTM":"2021-02-11 22:28:08","TRT02EDTM":"2022-02-12 04:28:08","AP01SDTM":"2019-02-24 11:09:25","AP01EDTM":"2021-02-11 22:28:08","AP02SDTM":"2021-02-11 22:28:08","AP02EDTM":"2022-02-12 04:28:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":1084,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":1105,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3815,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.74898,"AVALU":"U/L","BASE2":11.73546,"BASE":2.42964,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.01352,"PCHG2":59.76346,"CHG":16.31934,"PCHG":671.67646,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-06-18 11:09:25","ADY":480,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-128","SUBJID":"id-128","SITEID":"CHN-3","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":14.42493,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-22","TRTSDTM":"2019-02-24 11:09:25","TRTEDTM":"2022-02-12 04:28:08","TRT01SDTM":"2019-02-24 11:09:25","TRT01EDTM":"2021-02-11 22:28:08","TRT02SDTM":"2021-02-11 22:28:08","TRT02EDTM":"2022-02-12 04:28:08","AP01SDTM":"2019-02-24 11:09:25","AP01EDTM":"2021-02-11 22:28:08","AP02SDTM":"2021-02-11 22:28:08","AP02EDTM":"2022-02-12 04:28:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":1084,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":1105,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":163,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.96367,"AVALU":"mg/L","BASE2":9.96367,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-06-16 11:09:25","ADY":112,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-128","SUBJID":"id-128","SITEID":"CHN-3","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":14.42493,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-22","TRTSDTM":"2019-02-24 11:09:25","TRTEDTM":"2022-02-12 04:28:08","TRT01SDTM":"2019-02-24 11:09:25","TRT01EDTM":"2021-02-11 22:28:08","TRT02SDTM":"2021-02-11 22:28:08","TRT02EDTM":"2022-02-12 04:28:08","AP01SDTM":"2019-02-24 11:09:25","AP01EDTM":"2021-02-11 22:28:08","AP02SDTM":"2021-02-11 22:28:08","AP02EDTM":"2022-02-12 04:28:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":1084,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":1105,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5168,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.19567,"AVALU":"mg/L","BASE2":9.96367,"BASE":8.19567,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.76801,"PCHG2":-17.74451,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-25 11:09:25","ADY":151,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-128","SUBJID":"id-128","SITEID":"CHN-3","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":14.42493,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-22","TRTSDTM":"2019-02-24 11:09:25","TRTEDTM":"2022-02-12 04:28:08","TRT01SDTM":"2019-02-24 11:09:25","TRT01EDTM":"2021-02-11 22:28:08","TRT02SDTM":"2021-02-11 22:28:08","TRT02EDTM":"2022-02-12 04:28:08","AP01SDTM":"2019-02-24 11:09:25","AP01EDTM":"2021-02-11 22:28:08","AP02SDTM":"2021-02-11 22:28:08","AP02EDTM":"2022-02-12 04:28:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":1084,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":1105,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2701,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.82506,"AVALU":"mg/L","BASE2":9.96367,"BASE":8.19567,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.13861,"PCHG2":-21.46412,"CHG":-0.37061,"PCHG":-4.52201,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2019-10-20 11:09:25","ADY":238,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-128","SUBJID":"id-128","SITEID":"CHN-3","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":14.42493,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-22","TRTSDTM":"2019-02-24 11:09:25","TRTEDTM":"2022-02-12 04:28:08","TRT01SDTM":"2019-02-24 11:09:25","TRT01EDTM":"2021-02-11 22:28:08","TRT02SDTM":"2021-02-11 22:28:08","TRT02EDTM":"2022-02-12 04:28:08","AP01SDTM":"2019-02-24 11:09:25","AP01EDTM":"2021-02-11 22:28:08","AP02SDTM":"2021-02-11 22:28:08","AP02EDTM":"2022-02-12 04:28:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":1084,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":1105,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7991,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.24617,"AVALU":"mg/L","BASE2":9.96367,"BASE":8.19567,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.28249,"PCHG2":2.83524,"CHG":2.0505,"PCHG":25.01931,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2019-10-24 11:09:25","ADY":242,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-128","SUBJID":"id-128","SITEID":"CHN-3","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":14.42493,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-22","TRTSDTM":"2019-02-24 11:09:25","TRTEDTM":"2022-02-12 04:28:08","TRT01SDTM":"2019-02-24 11:09:25","TRT01EDTM":"2021-02-11 22:28:08","TRT02SDTM":"2021-02-11 22:28:08","TRT02EDTM":"2022-02-12 04:28:08","AP01SDTM":"2019-02-24 11:09:25","AP01EDTM":"2021-02-11 22:28:08","AP02SDTM":"2021-02-11 22:28:08","AP02EDTM":"2022-02-12 04:28:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":1084,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":1105,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6278,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.37188,"AVALU":"mg/L","BASE2":9.96367,"BASE":8.19567,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.59179,"PCHG2":-5.93947,"CHG":1.17622,"PCHG":14.35169,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-03 11:09:25","ADY":313,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-128","SUBJID":"id-128","SITEID":"CHN-3","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":14.42493,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-22","TRTSDTM":"2019-02-24 11:09:25","TRTEDTM":"2022-02-12 04:28:08","TRT01SDTM":"2019-02-24 11:09:25","TRT01EDTM":"2021-02-11 22:28:08","TRT02SDTM":"2021-02-11 22:28:08","TRT02EDTM":"2022-02-12 04:28:08","AP01SDTM":"2019-02-24 11:09:25","AP01EDTM":"2021-02-11 22:28:08","AP02SDTM":"2021-02-11 22:28:08","AP02EDTM":"2022-02-12 04:28:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":1084,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":1105,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7318,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.48119,"AVALU":"mg/L","BASE2":9.96367,"BASE":8.19567,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.48248,"PCHG2":-14.87886,"CHG":0.28552,"PCHG":3.48384,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-23 11:09:25","ADY":393,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-128","SUBJID":"id-128","SITEID":"CHN-3","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":14.42493,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-22","TRTSDTM":"2019-02-24 11:09:25","TRTEDTM":"2022-02-12 04:28:08","TRT01SDTM":"2019-02-24 11:09:25","TRT01EDTM":"2021-02-11 22:28:08","TRT02SDTM":"2021-02-11 22:28:08","TRT02EDTM":"2022-02-12 04:28:08","AP01SDTM":"2019-02-24 11:09:25","AP01EDTM":"2021-02-11 22:28:08","AP02SDTM":"2021-02-11 22:28:08","AP02EDTM":"2022-02-12 04:28:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":1084,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":1105,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5604,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.85763,"AVALU":"mg/L","BASE2":9.96367,"BASE":8.19567,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10604,"PCHG2":-1.06426,"CHG":1.66197,"PCHG":20.27859,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-18 11:09:25","ADY":480,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-128","SUBJID":"id-128","SITEID":"CHN-3","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":14.42493,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-22","TRTSDTM":"2019-02-24 11:09:25","TRTEDTM":"2022-02-12 04:28:08","TRT01SDTM":"2019-02-24 11:09:25","TRT01EDTM":"2021-02-11 22:28:08","TRT02SDTM":"2021-02-11 22:28:08","TRT02EDTM":"2022-02-12 04:28:08","AP01SDTM":"2019-02-24 11:09:25","AP01EDTM":"2021-02-11 22:28:08","AP02SDTM":"2021-02-11 22:28:08","AP02EDTM":"2022-02-12 04:28:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":1084,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":1105,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2462,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84771,"AVALU":"g/L","BASE2":2.84771,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"4","ADTM":"2019-06-16 11:09:25","ADY":112,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-128","SUBJID":"id-128","SITEID":"CHN-3","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":14.42493,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-22","TRTSDTM":"2019-02-24 11:09:25","TRTEDTM":"2022-02-12 04:28:08","TRT01SDTM":"2019-02-24 11:09:25","TRT01EDTM":"2021-02-11 22:28:08","TRT02SDTM":"2021-02-11 22:28:08","TRT02EDTM":"2022-02-12 04:28:08","AP01SDTM":"2019-02-24 11:09:25","AP01EDTM":"2021-02-11 22:28:08","AP02SDTM":"2021-02-11 22:28:08","AP02EDTM":"2022-02-12 04:28:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":1084,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":1105,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5362,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00796,"AVALU":"g/L","BASE2":2.84771,"BASE":3.00796,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.16025,"PCHG2":5.62733,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"4","BTOXGR":"4","ADTM":"2019-07-25 11:09:25","ADY":151,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-128","SUBJID":"id-128","SITEID":"CHN-3","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":14.42493,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-22","TRTSDTM":"2019-02-24 11:09:25","TRTEDTM":"2022-02-12 04:28:08","TRT01SDTM":"2019-02-24 11:09:25","TRT01EDTM":"2021-02-11 22:28:08","TRT02SDTM":"2021-02-11 22:28:08","TRT02EDTM":"2022-02-12 04:28:08","AP01SDTM":"2019-02-24 11:09:25","AP01EDTM":"2021-02-11 22:28:08","AP02SDTM":"2021-02-11 22:28:08","AP02EDTM":"2022-02-12 04:28:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":1084,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":1105,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1238,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92353,"AVALU":"g/L","BASE2":2.84771,"BASE":3.00796,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07583,"PCHG2":2.66277,"CHG":-0.08442,"PCHG":-2.80662,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2019-10-20 11:09:25","ADY":238,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-128","SUBJID":"id-128","SITEID":"CHN-3","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":14.42493,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-22","TRTSDTM":"2019-02-24 11:09:25","TRTEDTM":"2022-02-12 04:28:08","TRT01SDTM":"2019-02-24 11:09:25","TRT01EDTM":"2021-02-11 22:28:08","TRT02SDTM":"2021-02-11 22:28:08","TRT02EDTM":"2022-02-12 04:28:08","AP01SDTM":"2019-02-24 11:09:25","AP01EDTM":"2021-02-11 22:28:08","AP02SDTM":"2021-02-11 22:28:08","AP02EDTM":"2022-02-12 04:28:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":1084,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":1105,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1254,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.66766,"AVALU":"g/L","BASE2":2.84771,"BASE":3.00796,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18005,"PCHG2":-6.32261,"CHG":-0.3403,"PCHG":-11.3133,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2019-10-24 11:09:25","ADY":242,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-128","SUBJID":"id-128","SITEID":"CHN-3","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":14.42493,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-22","TRTSDTM":"2019-02-24 11:09:25","TRTEDTM":"2022-02-12 04:28:08","TRT01SDTM":"2019-02-24 11:09:25","TRT01EDTM":"2021-02-11 22:28:08","TRT02SDTM":"2021-02-11 22:28:08","TRT02EDTM":"2022-02-12 04:28:08","AP01SDTM":"2019-02-24 11:09:25","AP01EDTM":"2021-02-11 22:28:08","AP02SDTM":"2021-02-11 22:28:08","AP02EDTM":"2022-02-12 04:28:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":1084,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":1105,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7475,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82572,"AVALU":"g/L","BASE2":2.84771,"BASE":3.00796,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02199,"PCHG2":-0.77223,"CHG":-0.18224,"PCHG":-6.05862,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2020-01-03 11:09:25","ADY":313,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-128","SUBJID":"id-128","SITEID":"CHN-3","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":14.42493,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-22","TRTSDTM":"2019-02-24 11:09:25","TRTEDTM":"2022-02-12 04:28:08","TRT01SDTM":"2019-02-24 11:09:25","TRT01EDTM":"2021-02-11 22:28:08","TRT02SDTM":"2021-02-11 22:28:08","TRT02EDTM":"2022-02-12 04:28:08","AP01SDTM":"2019-02-24 11:09:25","AP01EDTM":"2021-02-11 22:28:08","AP02SDTM":"2021-02-11 22:28:08","AP02EDTM":"2022-02-12 04:28:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":1084,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":1105,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7174,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04561,"AVALU":"g/L","BASE2":2.84771,"BASE":3.00796,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1979,"PCHG2":6.94951,"CHG":0.03765,"PCHG":1.25174,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"4","ADTM":"2020-03-23 11:09:25","ADY":393,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-128","SUBJID":"id-128","SITEID":"CHN-3","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":14.42493,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-02-22","TRTSDTM":"2019-02-24 11:09:25","TRTEDTM":"2022-02-12 04:28:08","TRT01SDTM":"2019-02-24 11:09:25","TRT01EDTM":"2021-02-11 22:28:08","TRT02SDTM":"2021-02-11 22:28:08","TRT02EDTM":"2022-02-12 04:28:08","AP01SDTM":"2019-02-24 11:09:25","AP01EDTM":"2021-02-11 22:28:08","AP02SDTM":"2021-02-11 22:28:08","AP02EDTM":"2022-02-12 04:28:08","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":1084,"DCSREAS":"DEATH","DTHDT":"2022-03-06","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-06","DTHADY":1105,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3757,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78248,"AVALU":"g/L","BASE2":2.84771,"BASE":3.00796,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06522,"PCHG2":-2.29035,"CHG":-0.22547,"PCHG":-7.49586,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2020-06-18 11:09:25","ADY":480,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-155","SUBJID":"id-155","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.27087,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-20 13:11:59","TRTEDTM":"2023-05-21 07:11:59","TRT01SDTM":"2020-05-20 13:11:59","TRT01EDTM":"2022-05-21 01:11:59","TRT02SDTM":"2022-05-21 01:11:59","TRT02EDTM":"2023-05-21 07:11:59","AP01SDTM":"2020-05-20 13:11:59","AP01EDTM":"2022-05-21 01:11:59","AP02SDTM":"2022-05-21 01:11:59","AP02EDTM":"2023-05-21 07:11:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-21","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2081,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.7274,"AVALU":"U/L","BASE2":23.7274,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-07 13:11:59","ADY":140,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-155","SUBJID":"id-155","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.27087,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-20 13:11:59","TRTEDTM":"2023-05-21 07:11:59","TRT01SDTM":"2020-05-20 13:11:59","TRT01EDTM":"2022-05-21 01:11:59","TRT02SDTM":"2022-05-21 01:11:59","TRT02EDTM":"2023-05-21 07:11:59","AP01SDTM":"2020-05-20 13:11:59","AP01EDTM":"2022-05-21 01:11:59","AP02SDTM":"2022-05-21 01:11:59","AP02EDTM":"2023-05-21 07:11:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-21","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3261,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.87709,"AVALU":"U/L","BASE2":23.7274,"BASE":31.87709,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":8.14969,"PCHG2":34.34719,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-29 13:11:59","ADY":193,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-155","SUBJID":"id-155","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.27087,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-20 13:11:59","TRTEDTM":"2023-05-21 07:11:59","TRT01SDTM":"2020-05-20 13:11:59","TRT01EDTM":"2022-05-21 01:11:59","TRT02SDTM":"2022-05-21 01:11:59","TRT02EDTM":"2023-05-21 07:11:59","AP01SDTM":"2020-05-20 13:11:59","AP01EDTM":"2022-05-21 01:11:59","AP02SDTM":"2022-05-21 01:11:59","AP02EDTM":"2023-05-21 07:11:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-21","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7034,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.86581,"AVALU":"U/L","BASE2":23.7274,"BASE":31.87709,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.13842,"PCHG2":13.22697,"CHG":-5.01128,"PCHG":-15.72063,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-25 13:11:59","ADY":340,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-155","SUBJID":"id-155","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.27087,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-20 13:11:59","TRTEDTM":"2023-05-21 07:11:59","TRT01SDTM":"2020-05-20 13:11:59","TRT01EDTM":"2022-05-21 01:11:59","TRT02SDTM":"2022-05-21 01:11:59","TRT02EDTM":"2023-05-21 07:11:59","AP01SDTM":"2020-05-20 13:11:59","AP01EDTM":"2022-05-21 01:11:59","AP02SDTM":"2022-05-21 01:11:59","AP02EDTM":"2023-05-21 07:11:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-21","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3811,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.13211,"AVALU":"U/L","BASE2":23.7274,"BASE":31.87709,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.59529,"PCHG2":-69.94147,"CHG":-24.74498,"PCHG":-77.62623,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-23 13:11:59","ADY":429,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-155","SUBJID":"id-155","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.27087,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-20 13:11:59","TRTEDTM":"2023-05-21 07:11:59","TRT01SDTM":"2020-05-20 13:11:59","TRT01EDTM":"2022-05-21 01:11:59","TRT02SDTM":"2022-05-21 01:11:59","TRT02EDTM":"2023-05-21 07:11:59","AP01SDTM":"2020-05-20 13:11:59","AP01EDTM":"2022-05-21 01:11:59","AP02SDTM":"2022-05-21 01:11:59","AP02EDTM":"2023-05-21 07:11:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-21","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3054,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.12282,"AVALU":"U/L","BASE2":23.7274,"BASE":31.87709,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.60458,"PCHG2":-69.98061,"CHG":-24.75427,"PCHG":-77.65537,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-27 13:11:59","ADY":676,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-155","SUBJID":"id-155","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.27087,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-20 13:11:59","TRTEDTM":"2023-05-21 07:11:59","TRT01SDTM":"2020-05-20 13:11:59","TRT01EDTM":"2022-05-21 01:11:59","TRT02SDTM":"2022-05-21 01:11:59","TRT02EDTM":"2023-05-21 07:11:59","AP01SDTM":"2020-05-20 13:11:59","AP01EDTM":"2022-05-21 01:11:59","AP02SDTM":"2022-05-21 01:11:59","AP02EDTM":"2023-05-21 07:11:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-21","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5696,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.86041,"AVALU":"U/L","BASE2":23.7274,"BASE":31.87709,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.86699,"PCHG2":-54.2284,"CHG":-21.01668,"PCHG":-65.93036,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-01 13:11:59","ADY":803,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-155","SUBJID":"id-155","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.27087,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-20 13:11:59","TRTEDTM":"2023-05-21 07:11:59","TRT01SDTM":"2020-05-20 13:11:59","TRT01EDTM":"2022-05-21 01:11:59","TRT02SDTM":"2022-05-21 01:11:59","TRT02EDTM":"2023-05-21 07:11:59","AP01SDTM":"2020-05-20 13:11:59","AP01EDTM":"2022-05-21 01:11:59","AP02SDTM":"2022-05-21 01:11:59","AP02EDTM":"2023-05-21 07:11:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-21","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8285,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.26317,"AVALU":"U/L","BASE2":23.7274,"BASE":31.87709,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.46423,"PCHG2":-48.31641,"CHG":-19.61392,"PCHG":-61.52983,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-22 13:11:59","ADY":824,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-155","SUBJID":"id-155","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.27087,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-20 13:11:59","TRTEDTM":"2023-05-21 07:11:59","TRT01SDTM":"2020-05-20 13:11:59","TRT01EDTM":"2022-05-21 01:11:59","TRT02SDTM":"2022-05-21 01:11:59","TRT02EDTM":"2023-05-21 07:11:59","AP01SDTM":"2020-05-20 13:11:59","AP01EDTM":"2022-05-21 01:11:59","AP02SDTM":"2022-05-21 01:11:59","AP02EDTM":"2023-05-21 07:11:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-21","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6229,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.32441,"AVALU":"mg/L","BASE2":10.32441,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-10-07 13:11:59","ADY":140,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-155","SUBJID":"id-155","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.27087,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-20 13:11:59","TRTEDTM":"2023-05-21 07:11:59","TRT01SDTM":"2020-05-20 13:11:59","TRT01EDTM":"2022-05-21 01:11:59","TRT02SDTM":"2022-05-21 01:11:59","TRT02EDTM":"2023-05-21 07:11:59","AP01SDTM":"2020-05-20 13:11:59","AP01EDTM":"2022-05-21 01:11:59","AP02SDTM":"2022-05-21 01:11:59","AP02EDTM":"2023-05-21 07:11:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-21","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3266,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.26538,"AVALU":"mg/L","BASE2":10.32441,"BASE":8.26538,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.05903,"PCHG2":-19.94329,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-29 13:11:59","ADY":193,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-155","SUBJID":"id-155","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.27087,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-20 13:11:59","TRTEDTM":"2023-05-21 07:11:59","TRT01SDTM":"2020-05-20 13:11:59","TRT01EDTM":"2022-05-21 01:11:59","TRT02SDTM":"2022-05-21 01:11:59","TRT02EDTM":"2023-05-21 07:11:59","AP01SDTM":"2020-05-20 13:11:59","AP01EDTM":"2022-05-21 01:11:59","AP02SDTM":"2022-05-21 01:11:59","AP02EDTM":"2023-05-21 07:11:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-21","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7178,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.31418,"AVALU":"mg/L","BASE2":10.32441,"BASE":8.26538,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01023,"PCHG2":-0.09909,"CHG":2.0488,"PCHG":24.78768,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-04-25 13:11:59","ADY":340,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-155","SUBJID":"id-155","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.27087,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-20 13:11:59","TRTEDTM":"2023-05-21 07:11:59","TRT01SDTM":"2020-05-20 13:11:59","TRT01EDTM":"2022-05-21 01:11:59","TRT02SDTM":"2022-05-21 01:11:59","TRT02EDTM":"2023-05-21 07:11:59","AP01SDTM":"2020-05-20 13:11:59","AP01EDTM":"2022-05-21 01:11:59","AP02SDTM":"2022-05-21 01:11:59","AP02EDTM":"2023-05-21 07:11:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-21","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3964,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.9691,"AVALU":"mg/L","BASE2":10.32441,"BASE":8.26538,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.3553,"PCHG2":-3.44141,"CHG":1.70372,"PCHG":20.61274,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-23 13:11:59","ADY":429,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-155","SUBJID":"id-155","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.27087,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-20 13:11:59","TRTEDTM":"2023-05-21 07:11:59","TRT01SDTM":"2020-05-20 13:11:59","TRT01EDTM":"2022-05-21 01:11:59","TRT02SDTM":"2022-05-21 01:11:59","TRT02EDTM":"2023-05-21 07:11:59","AP01SDTM":"2020-05-20 13:11:59","AP01EDTM":"2022-05-21 01:11:59","AP02SDTM":"2022-05-21 01:11:59","AP02EDTM":"2023-05-21 07:11:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-21","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2871,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.49874,"AVALU":"mg/L","BASE2":10.32441,"BASE":8.26538,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.82566,"PCHG2":-27.36876,"CHG":-0.76664,"PCHG":-9.27526,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-03-27 13:11:59","ADY":676,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-155","SUBJID":"id-155","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.27087,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-20 13:11:59","TRTEDTM":"2023-05-21 07:11:59","TRT01SDTM":"2020-05-20 13:11:59","TRT01EDTM":"2022-05-21 01:11:59","TRT02SDTM":"2022-05-21 01:11:59","TRT02EDTM":"2023-05-21 07:11:59","AP01SDTM":"2020-05-20 13:11:59","AP01EDTM":"2022-05-21 01:11:59","AP02SDTM":"2022-05-21 01:11:59","AP02EDTM":"2023-05-21 07:11:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-21","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4447,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.13363,"AVALU":"mg/L","BASE2":10.32441,"BASE":8.26538,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19078,"PCHG2":-1.84785,"CHG":1.86825,"PCHG":22.60327,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-08-01 13:11:59","ADY":803,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-155","SUBJID":"id-155","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.27087,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-20 13:11:59","TRTEDTM":"2023-05-21 07:11:59","TRT01SDTM":"2020-05-20 13:11:59","TRT01EDTM":"2022-05-21 01:11:59","TRT02SDTM":"2022-05-21 01:11:59","TRT02EDTM":"2023-05-21 07:11:59","AP01SDTM":"2020-05-20 13:11:59","AP01EDTM":"2022-05-21 01:11:59","AP02SDTM":"2022-05-21 01:11:59","AP02EDTM":"2023-05-21 07:11:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-21","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3541,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.22286,"AVALU":"mg/L","BASE2":10.32441,"BASE":8.26538,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.10155,"PCHG2":-10.66935,"CHG":0.95748,"PCHG":11.58421,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-22 13:11:59","ADY":824,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-155","SUBJID":"id-155","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.27087,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-20 13:11:59","TRTEDTM":"2023-05-21 07:11:59","TRT01SDTM":"2020-05-20 13:11:59","TRT01EDTM":"2022-05-21 01:11:59","TRT02SDTM":"2022-05-21 01:11:59","TRT02EDTM":"2023-05-21 07:11:59","AP01SDTM":"2020-05-20 13:11:59","AP01EDTM":"2022-05-21 01:11:59","AP02SDTM":"2022-05-21 01:11:59","AP02EDTM":"2023-05-21 07:11:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-21","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6792,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83128,"AVALU":"g/L","BASE2":2.83128,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-07 13:11:59","ADY":140,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-155","SUBJID":"id-155","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.27087,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-20 13:11:59","TRTEDTM":"2023-05-21 07:11:59","TRT01SDTM":"2020-05-20 13:11:59","TRT01EDTM":"2022-05-21 01:11:59","TRT02SDTM":"2022-05-21 01:11:59","TRT02EDTM":"2023-05-21 07:11:59","AP01SDTM":"2020-05-20 13:11:59","AP01EDTM":"2022-05-21 01:11:59","AP02SDTM":"2022-05-21 01:11:59","AP02EDTM":"2023-05-21 07:11:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-21","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7266,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78375,"AVALU":"g/L","BASE2":2.83128,"BASE":2.78375,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.04752,"PCHG2":-1.67844,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-29 13:11:59","ADY":193,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-155","SUBJID":"id-155","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.27087,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-20 13:11:59","TRTEDTM":"2023-05-21 07:11:59","TRT01SDTM":"2020-05-20 13:11:59","TRT01EDTM":"2022-05-21 01:11:59","TRT02SDTM":"2022-05-21 01:11:59","TRT02EDTM":"2023-05-21 07:11:59","AP01SDTM":"2020-05-20 13:11:59","AP01EDTM":"2022-05-21 01:11:59","AP02SDTM":"2022-05-21 01:11:59","AP02EDTM":"2023-05-21 07:11:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-21","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2233,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8169,"AVALU":"g/L","BASE2":2.83128,"BASE":2.78375,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01438,"PCHG2":-0.50789,"CHG":0.03314,"PCHG":1.19053,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-25 13:11:59","ADY":340,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-155","SUBJID":"id-155","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.27087,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-20 13:11:59","TRTEDTM":"2023-05-21 07:11:59","TRT01SDTM":"2020-05-20 13:11:59","TRT01EDTM":"2022-05-21 01:11:59","TRT02SDTM":"2022-05-21 01:11:59","TRT02EDTM":"2023-05-21 07:11:59","AP01SDTM":"2020-05-20 13:11:59","AP01EDTM":"2022-05-21 01:11:59","AP02SDTM":"2022-05-21 01:11:59","AP02EDTM":"2023-05-21 07:11:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-21","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5194,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79874,"AVALU":"g/L","BASE2":2.83128,"BASE":2.78375,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03254,"PCHG2":-1.14921,"CHG":0.01498,"PCHG":0.53827,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-23 13:11:59","ADY":429,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-155","SUBJID":"id-155","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.27087,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-20 13:11:59","TRTEDTM":"2023-05-21 07:11:59","TRT01SDTM":"2020-05-20 13:11:59","TRT01EDTM":"2022-05-21 01:11:59","TRT02SDTM":"2022-05-21 01:11:59","TRT02EDTM":"2023-05-21 07:11:59","AP01SDTM":"2020-05-20 13:11:59","AP01EDTM":"2022-05-21 01:11:59","AP02SDTM":"2022-05-21 01:11:59","AP02EDTM":"2023-05-21 07:11:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-21","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1575,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.06907,"AVALU":"g/L","BASE2":2.83128,"BASE":2.78375,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.23779,"PCHG2":8.39877,"CHG":0.28531,"PCHG":10.24923,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-03-27 13:11:59","ADY":676,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-155","SUBJID":"id-155","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.27087,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-20 13:11:59","TRTEDTM":"2023-05-21 07:11:59","TRT01SDTM":"2020-05-20 13:11:59","TRT01EDTM":"2022-05-21 01:11:59","TRT02SDTM":"2022-05-21 01:11:59","TRT02EDTM":"2023-05-21 07:11:59","AP01SDTM":"2020-05-20 13:11:59","AP01EDTM":"2022-05-21 01:11:59","AP02SDTM":"2022-05-21 01:11:59","AP02EDTM":"2023-05-21 07:11:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-21","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5197,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94803,"AVALU":"g/L","BASE2":2.83128,"BASE":2.78375,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11675,"PCHG2":4.12372,"CHG":0.16428,"PCHG":5.90121,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-01 13:11:59","ADY":803,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-155","SUBJID":"id-155","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.27087,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-17","TRTSDTM":"2020-05-20 13:11:59","TRTEDTM":"2023-05-21 07:11:59","TRT01SDTM":"2020-05-20 13:11:59","TRT01EDTM":"2022-05-21 01:11:59","TRT02SDTM":"2022-05-21 01:11:59","TRT02EDTM":"2023-05-21 07:11:59","AP01SDTM":"2020-05-20 13:11:59","AP01EDTM":"2022-05-21 01:11:59","AP02SDTM":"2022-05-21 01:11:59","AP02EDTM":"2023-05-21 07:11:59","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-21","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6830,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82011,"AVALU":"g/L","BASE2":2.83128,"BASE":2.78375,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01117,"PCHG2":-0.39437,"CHG":0.03636,"PCHG":1.30598,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-22 13:11:59","ADY":824,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-193","SUBJID":"id-193","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.46044,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-24","TRTSDTM":"2021-01-26 01:09:53","TRTEDTM":"2022-02-13 13:07:25","TRT01SDTM":"2021-01-26 01:09:53","TRT01EDTM":"2021-02-13 07:07:25","TRT02SDTM":"2021-02-13 07:07:25","TRT02EDTM":"2022-02-13 13:07:25","AP01SDTM":"2021-01-26 01:09:53","AP01EDTM":"2021-02-13 07:07:25","AP02SDTM":"2021-02-13 07:07:25","AP02EDTM":"2022-02-13 13:07:25","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":384,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-12","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3190,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.06605,"AVALU":"U/L","BASE2":21.06605,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-21 01:09:53","ADY":54,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-193","SUBJID":"id-193","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.46044,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-24","TRTSDTM":"2021-01-26 01:09:53","TRTEDTM":"2022-02-13 13:07:25","TRT01SDTM":"2021-01-26 01:09:53","TRT01EDTM":"2021-02-13 07:07:25","TRT02SDTM":"2021-02-13 07:07:25","TRT02EDTM":"2022-02-13 13:07:25","AP01SDTM":"2021-01-26 01:09:53","AP01EDTM":"2021-02-13 07:07:25","AP02SDTM":"2021-02-13 07:07:25","AP02EDTM":"2022-02-13 13:07:25","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":384,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-12","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1845,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.06373,"AVALU":"U/L","BASE2":21.06605,"BASE":30.06373,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":8.99768,"PCHG2":42.71175,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-31 01:09:53","ADY":64,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-193","SUBJID":"id-193","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.46044,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-24","TRTSDTM":"2021-01-26 01:09:53","TRTEDTM":"2022-02-13 13:07:25","TRT01SDTM":"2021-01-26 01:09:53","TRT01EDTM":"2021-02-13 07:07:25","TRT02SDTM":"2021-02-13 07:07:25","TRT02EDTM":"2022-02-13 13:07:25","AP01SDTM":"2021-01-26 01:09:53","AP01EDTM":"2021-02-13 07:07:25","AP02SDTM":"2021-02-13 07:07:25","AP02EDTM":"2022-02-13 13:07:25","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":384,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-12","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5484,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.4184,"AVALU":"U/L","BASE2":21.06605,"BASE":30.06373,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.64765,"PCHG2":-7.82135,"CHG":-10.64533,"PCHG":-35.40921,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-26 01:09:53","ADY":151,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-193","SUBJID":"id-193","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.46044,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-24","TRTSDTM":"2021-01-26 01:09:53","TRTEDTM":"2022-02-13 13:07:25","TRT01SDTM":"2021-01-26 01:09:53","TRT01EDTM":"2021-02-13 07:07:25","TRT02SDTM":"2021-02-13 07:07:25","TRT02EDTM":"2022-02-13 13:07:25","AP01SDTM":"2021-01-26 01:09:53","AP01EDTM":"2021-02-13 07:07:25","AP02SDTM":"2021-02-13 07:07:25","AP02EDTM":"2022-02-13 13:07:25","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":384,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-12","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5699,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.68188,"AVALU":"U/L","BASE2":21.06605,"BASE":30.06373,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.61584,"PCHG2":17.16428,"CHG":-5.38184,"PCHG":-17.90145,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-03 01:09:53","ADY":158,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-193","SUBJID":"id-193","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.46044,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-24","TRTSDTM":"2021-01-26 01:09:53","TRTEDTM":"2022-02-13 13:07:25","TRT01SDTM":"2021-01-26 01:09:53","TRT01EDTM":"2021-02-13 07:07:25","TRT02SDTM":"2021-02-13 07:07:25","TRT02EDTM":"2022-02-13 13:07:25","AP01SDTM":"2021-01-26 01:09:53","AP01EDTM":"2021-02-13 07:07:25","AP02SDTM":"2021-02-13 07:07:25","AP02EDTM":"2022-02-13 13:07:25","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":384,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-12","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8256,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.24798,"AVALU":"U/L","BASE2":21.06605,"BASE":30.06373,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.81807,"PCHG2":-37.11216,"CHG":-16.81574,"PCHG":-55.93367,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-31 01:09:53","ADY":217,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-193","SUBJID":"id-193","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.46044,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-24","TRTSDTM":"2021-01-26 01:09:53","TRTEDTM":"2022-02-13 13:07:25","TRT01SDTM":"2021-01-26 01:09:53","TRT01EDTM":"2021-02-13 07:07:25","TRT02SDTM":"2021-02-13 07:07:25","TRT02EDTM":"2022-02-13 13:07:25","AP01SDTM":"2021-01-26 01:09:53","AP01EDTM":"2021-02-13 07:07:25","AP02SDTM":"2021-02-13 07:07:25","AP02EDTM":"2022-02-13 13:07:25","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":384,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-12","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":991,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.05585,"AVALU":"U/L","BASE2":21.06605,"BASE":30.06373,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.0102,"PCHG2":-42.7712,"CHG":-18.00788,"PCHG":-59.89903,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-03 01:09:53","ADY":220,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-193","SUBJID":"id-193","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.46044,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-24","TRTSDTM":"2021-01-26 01:09:53","TRTEDTM":"2022-02-13 13:07:25","TRT01SDTM":"2021-01-26 01:09:53","TRT01EDTM":"2021-02-13 07:07:25","TRT02SDTM":"2021-02-13 07:07:25","TRT02EDTM":"2022-02-13 13:07:25","AP01SDTM":"2021-01-26 01:09:53","AP01EDTM":"2021-02-13 07:07:25","AP02SDTM":"2021-02-13 07:07:25","AP02EDTM":"2022-02-13 13:07:25","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":384,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-12","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4116,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.93844,"AVALU":"U/L","BASE2":21.06605,"BASE":30.06373,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.12761,"PCHG2":-29.0876,"CHG":-15.12529,"PCHG":-50.31075,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-19 01:09:53","ADY":358,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-193","SUBJID":"id-193","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.46044,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-24","TRTSDTM":"2021-01-26 01:09:53","TRTEDTM":"2022-02-13 13:07:25","TRT01SDTM":"2021-01-26 01:09:53","TRT01EDTM":"2021-02-13 07:07:25","TRT02SDTM":"2021-02-13 07:07:25","TRT02EDTM":"2022-02-13 13:07:25","AP01SDTM":"2021-01-26 01:09:53","AP01EDTM":"2021-02-13 07:07:25","AP02SDTM":"2021-02-13 07:07:25","AP02EDTM":"2022-02-13 13:07:25","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":384,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-12","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8244,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.48252,"AVALU":"mg/L","BASE2":9.48252,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-21 01:09:53","ADY":54,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-193","SUBJID":"id-193","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.46044,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-24","TRTSDTM":"2021-01-26 01:09:53","TRTEDTM":"2022-02-13 13:07:25","TRT01SDTM":"2021-01-26 01:09:53","TRT01EDTM":"2021-02-13 07:07:25","TRT02SDTM":"2021-02-13 07:07:25","TRT02EDTM":"2022-02-13 13:07:25","AP01SDTM":"2021-01-26 01:09:53","AP01EDTM":"2021-02-13 07:07:25","AP02SDTM":"2021-02-13 07:07:25","AP02EDTM":"2022-02-13 13:07:25","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":384,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-12","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1654,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.67871,"AVALU":"mg/L","BASE2":9.48252,"BASE":9.67871,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.19619,"PCHG2":2.06896,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-31 01:09:53","ADY":64,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-193","SUBJID":"id-193","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.46044,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-24","TRTSDTM":"2021-01-26 01:09:53","TRTEDTM":"2022-02-13 13:07:25","TRT01SDTM":"2021-01-26 01:09:53","TRT01EDTM":"2021-02-13 07:07:25","TRT02SDTM":"2021-02-13 07:07:25","TRT02EDTM":"2022-02-13 13:07:25","AP01SDTM":"2021-01-26 01:09:53","AP01EDTM":"2021-02-13 07:07:25","AP02SDTM":"2021-02-13 07:07:25","AP02EDTM":"2022-02-13 13:07:25","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":384,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-12","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6355,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.90159,"AVALU":"mg/L","BASE2":9.48252,"BASE":9.67871,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.41906,"PCHG2":4.41933,"CHG":0.22287,"PCHG":2.30273,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-26 01:09:53","ADY":151,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-193","SUBJID":"id-193","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.46044,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-24","TRTSDTM":"2021-01-26 01:09:53","TRTEDTM":"2022-02-13 13:07:25","TRT01SDTM":"2021-01-26 01:09:53","TRT01EDTM":"2021-02-13 07:07:25","TRT02SDTM":"2021-02-13 07:07:25","TRT02EDTM":"2022-02-13 13:07:25","AP01SDTM":"2021-01-26 01:09:53","AP01EDTM":"2021-02-13 07:07:25","AP02SDTM":"2021-02-13 07:07:25","AP02EDTM":"2022-02-13 13:07:25","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":384,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-12","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3838,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.73095,"AVALU":"mg/L","BASE2":9.48252,"BASE":9.67871,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.24843,"PCHG2":2.61987,"CHG":0.05224,"PCHG":0.53974,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-03 01:09:53","ADY":158,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-193","SUBJID":"id-193","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.46044,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-24","TRTSDTM":"2021-01-26 01:09:53","TRTEDTM":"2022-02-13 13:07:25","TRT01SDTM":"2021-01-26 01:09:53","TRT01EDTM":"2021-02-13 07:07:25","TRT02SDTM":"2021-02-13 07:07:25","TRT02EDTM":"2022-02-13 13:07:25","AP01SDTM":"2021-01-26 01:09:53","AP01EDTM":"2021-02-13 07:07:25","AP02SDTM":"2021-02-13 07:07:25","AP02EDTM":"2022-02-13 13:07:25","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":384,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-12","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":811,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.57563,"AVALU":"mg/L","BASE2":9.48252,"BASE":9.67871,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.9069,"PCHG2":-9.56388,"CHG":-1.10309,"PCHG":-11.39703,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-31 01:09:53","ADY":217,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-193","SUBJID":"id-193","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.46044,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-24","TRTSDTM":"2021-01-26 01:09:53","TRTEDTM":"2022-02-13 13:07:25","TRT01SDTM":"2021-01-26 01:09:53","TRT01EDTM":"2021-02-13 07:07:25","TRT02SDTM":"2021-02-13 07:07:25","TRT02EDTM":"2022-02-13 13:07:25","AP01SDTM":"2021-01-26 01:09:53","AP01EDTM":"2021-02-13 07:07:25","AP02SDTM":"2021-02-13 07:07:25","AP02EDTM":"2022-02-13 13:07:25","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":384,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-12","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6625,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.71554,"AVALU":"mg/L","BASE2":9.48252,"BASE":9.67871,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.76698,"PCHG2":-8.08839,"CHG":-0.96317,"PCHG":-9.95146,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-03 01:09:53","ADY":220,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-193","SUBJID":"id-193","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.46044,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-24","TRTSDTM":"2021-01-26 01:09:53","TRTEDTM":"2022-02-13 13:07:25","TRT01SDTM":"2021-01-26 01:09:53","TRT01EDTM":"2021-02-13 07:07:25","TRT02SDTM":"2021-02-13 07:07:25","TRT02EDTM":"2022-02-13 13:07:25","AP01SDTM":"2021-01-26 01:09:53","AP01EDTM":"2021-02-13 07:07:25","AP02SDTM":"2021-02-13 07:07:25","AP02EDTM":"2022-02-13 13:07:25","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":384,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-12","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8206,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.39184,"AVALU":"mg/L","BASE2":9.48252,"BASE":9.67871,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09068,"PCHG2":-0.95633,"CHG":-0.28687,"PCHG":-2.96396,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-19 01:09:53","ADY":358,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-193","SUBJID":"id-193","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.46044,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-24","TRTSDTM":"2021-01-26 01:09:53","TRTEDTM":"2022-02-13 13:07:25","TRT01SDTM":"2021-01-26 01:09:53","TRT01EDTM":"2021-02-13 07:07:25","TRT02SDTM":"2021-02-13 07:07:25","TRT02EDTM":"2022-02-13 13:07:25","AP01SDTM":"2021-01-26 01:09:53","AP01EDTM":"2021-02-13 07:07:25","AP02SDTM":"2021-02-13 07:07:25","AP02EDTM":"2022-02-13 13:07:25","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":384,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-12","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7126,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84366,"AVALU":"g/L","BASE2":2.84366,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-21 01:09:53","ADY":54,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-193","SUBJID":"id-193","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.46044,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-24","TRTSDTM":"2021-01-26 01:09:53","TRTEDTM":"2022-02-13 13:07:25","TRT01SDTM":"2021-01-26 01:09:53","TRT01EDTM":"2021-02-13 07:07:25","TRT02SDTM":"2021-02-13 07:07:25","TRT02EDTM":"2022-02-13 13:07:25","AP01SDTM":"2021-01-26 01:09:53","AP01EDTM":"2021-02-13 07:07:25","AP02SDTM":"2021-02-13 07:07:25","AP02EDTM":"2022-02-13 13:07:25","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":384,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-12","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2547,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94504,"AVALU":"g/L","BASE2":2.84366,"BASE":2.94504,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.10138,"PCHG2":3.56499,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-31 01:09:53","ADY":64,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-193","SUBJID":"id-193","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.46044,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-24","TRTSDTM":"2021-01-26 01:09:53","TRTEDTM":"2022-02-13 13:07:25","TRT01SDTM":"2021-01-26 01:09:53","TRT01EDTM":"2021-02-13 07:07:25","TRT02SDTM":"2021-02-13 07:07:25","TRT02EDTM":"2022-02-13 13:07:25","AP01SDTM":"2021-01-26 01:09:53","AP01EDTM":"2021-02-13 07:07:25","AP02SDTM":"2021-02-13 07:07:25","AP02EDTM":"2022-02-13 13:07:25","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":384,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-12","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7142,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94361,"AVALU":"g/L","BASE2":2.84366,"BASE":2.94504,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09994,"PCHG2":3.51455,"CHG":-0.00143,"PCHG":-0.04871,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-26 01:09:53","ADY":151,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-193","SUBJID":"id-193","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.46044,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-24","TRTSDTM":"2021-01-26 01:09:53","TRTEDTM":"2022-02-13 13:07:25","TRT01SDTM":"2021-01-26 01:09:53","TRT01EDTM":"2021-02-13 07:07:25","TRT02SDTM":"2021-02-13 07:07:25","TRT02EDTM":"2022-02-13 13:07:25","AP01SDTM":"2021-01-26 01:09:53","AP01EDTM":"2021-02-13 07:07:25","AP02SDTM":"2021-02-13 07:07:25","AP02EDTM":"2022-02-13 13:07:25","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":384,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-12","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7284,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81075,"AVALU":"g/L","BASE2":2.84366,"BASE":2.94504,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03291,"PCHG2":-1.15739,"CHG":-0.13429,"PCHG":-4.55983,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-03 01:09:53","ADY":158,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-193","SUBJID":"id-193","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.46044,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-24","TRTSDTM":"2021-01-26 01:09:53","TRTEDTM":"2022-02-13 13:07:25","TRT01SDTM":"2021-01-26 01:09:53","TRT01EDTM":"2021-02-13 07:07:25","TRT02SDTM":"2021-02-13 07:07:25","TRT02EDTM":"2022-02-13 13:07:25","AP01SDTM":"2021-01-26 01:09:53","AP01EDTM":"2021-02-13 07:07:25","AP02SDTM":"2021-02-13 07:07:25","AP02EDTM":"2022-02-13 13:07:25","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":384,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-12","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5004,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77486,"AVALU":"g/L","BASE2":2.84366,"BASE":2.94504,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0688,"PCHG2":-2.41949,"CHG":-0.17018,"PCHG":-5.77848,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-31 01:09:53","ADY":217,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-193","SUBJID":"id-193","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.46044,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-24","TRTSDTM":"2021-01-26 01:09:53","TRTEDTM":"2022-02-13 13:07:25","TRT01SDTM":"2021-01-26 01:09:53","TRT01EDTM":"2021-02-13 07:07:25","TRT02SDTM":"2021-02-13 07:07:25","TRT02EDTM":"2022-02-13 13:07:25","AP01SDTM":"2021-01-26 01:09:53","AP01EDTM":"2021-02-13 07:07:25","AP02SDTM":"2021-02-13 07:07:25","AP02EDTM":"2022-02-13 13:07:25","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":384,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-12","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1848,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8483,"AVALU":"g/L","BASE2":2.84366,"BASE":2.94504,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00464,"PCHG2":0.16314,"CHG":-0.09674,"PCHG":-3.28475,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-03 01:09:53","ADY":220,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-193","SUBJID":"id-193","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.46044,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-24","TRTSDTM":"2021-01-26 01:09:53","TRTEDTM":"2022-02-13 13:07:25","TRT01SDTM":"2021-01-26 01:09:53","TRT01EDTM":"2021-02-13 07:07:25","TRT02SDTM":"2021-02-13 07:07:25","TRT02EDTM":"2022-02-13 13:07:25","AP01SDTM":"2021-01-26 01:09:53","AP01EDTM":"2021-02-13 07:07:25","AP02SDTM":"2021-02-13 07:07:25","AP02EDTM":"2022-02-13 13:07:25","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":384,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-03-12","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4904,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84597,"AVALU":"g/L","BASE2":2.84366,"BASE":2.94504,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00231,"PCHG2":0.08109,"CHG":-0.09907,"PCHG":-3.36398,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-19 01:09:53","ADY":358,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-204","SUBJID":"id-204","SITEID":"CHN-3","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.68264,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-06","TRTSDTM":"2019-08-08 21:00:24","TRTEDTM":"2022-08-08 15:00:24","TRT01SDTM":"2019-08-08 21:00:24","TRT01EDTM":"2021-08-08 09:00:24","TRT02SDTM":"2021-08-08 09:00:24","TRT02EDTM":"2022-08-08 15:00:24","AP01SDTM":"2019-08-08 21:00:24","AP01EDTM":"2021-08-08 09:00:24","AP02SDTM":"2021-08-08 09:00:24","AP02EDTM":"2022-08-08 15:00:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-08","EOSDY":1096,"LSTALVDT":"2022-08-29","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5477,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.10479,"AVALU":"U/L","BASE2":12.10479,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-08 21:00:24","ADY":670,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-204","SUBJID":"id-204","SITEID":"CHN-3","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.68264,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-06","TRTSDTM":"2019-08-08 21:00:24","TRTEDTM":"2022-08-08 15:00:24","TRT01SDTM":"2019-08-08 21:00:24","TRT01EDTM":"2021-08-08 09:00:24","TRT02SDTM":"2021-08-08 09:00:24","TRT02EDTM":"2022-08-08 15:00:24","AP01SDTM":"2019-08-08 21:00:24","AP01EDTM":"2021-08-08 09:00:24","AP02SDTM":"2021-08-08 09:00:24","AP02EDTM":"2022-08-08 15:00:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-08","EOSDY":1096,"LSTALVDT":"2022-08-29","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":189,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.89174,"AVALU":"U/L","BASE2":12.10479,"BASE":16.89174,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":4.78695,"PCHG2":39.54593,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-14 21:00:24","ADY":768,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-204","SUBJID":"id-204","SITEID":"CHN-3","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.68264,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-06","TRTSDTM":"2019-08-08 21:00:24","TRTEDTM":"2022-08-08 15:00:24","TRT01SDTM":"2019-08-08 21:00:24","TRT01EDTM":"2021-08-08 09:00:24","TRT02SDTM":"2021-08-08 09:00:24","TRT02EDTM":"2022-08-08 15:00:24","AP01SDTM":"2019-08-08 21:00:24","AP01EDTM":"2021-08-08 09:00:24","AP02SDTM":"2021-08-08 09:00:24","AP02EDTM":"2022-08-08 15:00:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-08","EOSDY":1096,"LSTALVDT":"2022-08-29","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7564,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.47697,"AVALU":"U/L","BASE2":12.10479,"BASE":16.89174,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.37218,"PCHG2":160.03729,"CHG":14.58523,"PCHG":86.34531,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-04 21:00:24","ADY":788,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-204","SUBJID":"id-204","SITEID":"CHN-3","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.68264,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-06","TRTSDTM":"2019-08-08 21:00:24","TRTEDTM":"2022-08-08 15:00:24","TRT01SDTM":"2019-08-08 21:00:24","TRT01EDTM":"2021-08-08 09:00:24","TRT02SDTM":"2021-08-08 09:00:24","TRT02EDTM":"2022-08-08 15:00:24","AP01SDTM":"2019-08-08 21:00:24","AP01EDTM":"2021-08-08 09:00:24","AP02SDTM":"2021-08-08 09:00:24","AP02EDTM":"2022-08-08 15:00:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-08","EOSDY":1096,"LSTALVDT":"2022-08-29","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6531,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.08057,"AVALU":"U/L","BASE2":12.10479,"BASE":16.89174,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.97578,"PCHG2":16.32228,"CHG":-2.81117,"PCHG":-16.64229,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-28 21:00:24","ADY":994,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-204","SUBJID":"id-204","SITEID":"CHN-3","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.68264,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-06","TRTSDTM":"2019-08-08 21:00:24","TRTEDTM":"2022-08-08 15:00:24","TRT01SDTM":"2019-08-08 21:00:24","TRT01EDTM":"2021-08-08 09:00:24","TRT02SDTM":"2021-08-08 09:00:24","TRT02EDTM":"2022-08-08 15:00:24","AP01SDTM":"2019-08-08 21:00:24","AP01EDTM":"2021-08-08 09:00:24","AP02SDTM":"2021-08-08 09:00:24","AP02EDTM":"2022-08-08 15:00:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-08","EOSDY":1096,"LSTALVDT":"2022-08-29","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4871,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.5133,"AVALU":"U/L","BASE2":12.10479,"BASE":16.89174,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.40851,"PCHG2":11.63596,"CHG":-3.37844,"PCHG":-20.00056,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-02 21:00:24","ADY":998,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-204","SUBJID":"id-204","SITEID":"CHN-3","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.68264,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-06","TRTSDTM":"2019-08-08 21:00:24","TRTEDTM":"2022-08-08 15:00:24","TRT01SDTM":"2019-08-08 21:00:24","TRT01EDTM":"2021-08-08 09:00:24","TRT02SDTM":"2021-08-08 09:00:24","TRT02EDTM":"2022-08-08 15:00:24","AP01SDTM":"2019-08-08 21:00:24","AP01EDTM":"2021-08-08 09:00:24","AP02SDTM":"2021-08-08 09:00:24","AP02EDTM":"2022-08-08 15:00:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-08","EOSDY":1096,"LSTALVDT":"2022-08-29","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3613,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.98064,"AVALU":"U/L","BASE2":12.10479,"BASE":16.89174,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":20.87585,"PCHG2":172.45937,"CHG":16.08889,"PCHG":95.24709,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-18 21:00:24","ADY":1014,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-204","SUBJID":"id-204","SITEID":"CHN-3","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.68264,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-06","TRTSDTM":"2019-08-08 21:00:24","TRTEDTM":"2022-08-08 15:00:24","TRT01SDTM":"2019-08-08 21:00:24","TRT01EDTM":"2021-08-08 09:00:24","TRT02SDTM":"2021-08-08 09:00:24","TRT02EDTM":"2022-08-08 15:00:24","AP01SDTM":"2019-08-08 21:00:24","AP01EDTM":"2021-08-08 09:00:24","AP02SDTM":"2021-08-08 09:00:24","AP02EDTM":"2022-08-08 15:00:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-08","EOSDY":1096,"LSTALVDT":"2022-08-29","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2367,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.00262,"AVALU":"U/L","BASE2":12.10479,"BASE":16.89174,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.89783,"PCHG2":32.20069,"CHG":-0.88912,"PCHG":-5.26367,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-24 21:00:24","ADY":1051,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-204","SUBJID":"id-204","SITEID":"CHN-3","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.68264,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-06","TRTSDTM":"2019-08-08 21:00:24","TRTEDTM":"2022-08-08 15:00:24","TRT01SDTM":"2019-08-08 21:00:24","TRT01EDTM":"2021-08-08 09:00:24","TRT02SDTM":"2021-08-08 09:00:24","TRT02EDTM":"2022-08-08 15:00:24","AP01SDTM":"2019-08-08 21:00:24","AP01EDTM":"2021-08-08 09:00:24","AP02SDTM":"2021-08-08 09:00:24","AP02EDTM":"2022-08-08 15:00:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-08","EOSDY":1096,"LSTALVDT":"2022-08-29","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6379,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.71572,"AVALU":"mg/L","BASE2":7.71572,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-06-08 21:00:24","ADY":670,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-204","SUBJID":"id-204","SITEID":"CHN-3","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.68264,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-06","TRTSDTM":"2019-08-08 21:00:24","TRTEDTM":"2022-08-08 15:00:24","TRT01SDTM":"2019-08-08 21:00:24","TRT01EDTM":"2021-08-08 09:00:24","TRT02SDTM":"2021-08-08 09:00:24","TRT02EDTM":"2022-08-08 15:00:24","AP01SDTM":"2019-08-08 21:00:24","AP01EDTM":"2021-08-08 09:00:24","AP02SDTM":"2021-08-08 09:00:24","AP02EDTM":"2022-08-08 15:00:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-08","EOSDY":1096,"LSTALVDT":"2022-08-29","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1261,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.98156,"AVALU":"mg/L","BASE2":7.71572,"BASE":9.98156,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.26585,"PCHG2":29.36665,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-14 21:00:24","ADY":768,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-204","SUBJID":"id-204","SITEID":"CHN-3","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.68264,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-06","TRTSDTM":"2019-08-08 21:00:24","TRTEDTM":"2022-08-08 15:00:24","TRT01SDTM":"2019-08-08 21:00:24","TRT01EDTM":"2021-08-08 09:00:24","TRT02SDTM":"2021-08-08 09:00:24","TRT02EDTM":"2022-08-08 15:00:24","AP01SDTM":"2019-08-08 21:00:24","AP01EDTM":"2021-08-08 09:00:24","AP02SDTM":"2021-08-08 09:00:24","AP02EDTM":"2022-08-08 15:00:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-08","EOSDY":1096,"LSTALVDT":"2022-08-29","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6170,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.29383,"AVALU":"mg/L","BASE2":7.71572,"BASE":9.98156,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.57811,"PCHG2":7.49264,"CHG":-1.68774,"PCHG":-16.90854,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-04 21:00:24","ADY":788,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-204","SUBJID":"id-204","SITEID":"CHN-3","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.68264,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-06","TRTSDTM":"2019-08-08 21:00:24","TRTEDTM":"2022-08-08 15:00:24","TRT01SDTM":"2019-08-08 21:00:24","TRT01EDTM":"2021-08-08 09:00:24","TRT02SDTM":"2021-08-08 09:00:24","TRT02EDTM":"2022-08-08 15:00:24","AP01SDTM":"2019-08-08 21:00:24","AP01EDTM":"2021-08-08 09:00:24","AP02SDTM":"2021-08-08 09:00:24","AP02EDTM":"2022-08-08 15:00:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-08","EOSDY":1096,"LSTALVDT":"2022-08-29","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5145,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.78393,"AVALU":"mg/L","BASE2":7.71572,"BASE":9.98156,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.93179,"PCHG2":-12.07652,"CHG":-3.19764,"PCHG":-32.03544,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2022-04-28 21:00:24","ADY":994,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-204","SUBJID":"id-204","SITEID":"CHN-3","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.68264,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-06","TRTSDTM":"2019-08-08 21:00:24","TRTEDTM":"2022-08-08 15:00:24","TRT01SDTM":"2019-08-08 21:00:24","TRT01EDTM":"2021-08-08 09:00:24","TRT02SDTM":"2021-08-08 09:00:24","TRT02EDTM":"2022-08-08 15:00:24","AP01SDTM":"2019-08-08 21:00:24","AP01EDTM":"2021-08-08 09:00:24","AP02SDTM":"2021-08-08 09:00:24","AP02EDTM":"2022-08-08 15:00:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-08","EOSDY":1096,"LSTALVDT":"2022-08-29","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1193,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.02702,"AVALU":"mg/L","BASE2":7.71572,"BASE":9.98156,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.31131,"PCHG2":4.03474,"CHG":-1.95454,"PCHG":-19.58149,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-02 21:00:24","ADY":998,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-204","SUBJID":"id-204","SITEID":"CHN-3","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.68264,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-06","TRTSDTM":"2019-08-08 21:00:24","TRTEDTM":"2022-08-08 15:00:24","TRT01SDTM":"2019-08-08 21:00:24","TRT01EDTM":"2021-08-08 09:00:24","TRT02SDTM":"2021-08-08 09:00:24","TRT02EDTM":"2022-08-08 15:00:24","AP01SDTM":"2019-08-08 21:00:24","AP01EDTM":"2021-08-08 09:00:24","AP02SDTM":"2021-08-08 09:00:24","AP02EDTM":"2022-08-08 15:00:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-08","EOSDY":1096,"LSTALVDT":"2022-08-29","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4412,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.2327,"AVALU":"mg/L","BASE2":7.71572,"BASE":9.98156,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.51698,"PCHG2":19.66094,"CHG":-0.74887,"PCHG":-7.50249,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-18 21:00:24","ADY":1014,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-204","SUBJID":"id-204","SITEID":"CHN-3","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.68264,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-06","TRTSDTM":"2019-08-08 21:00:24","TRTEDTM":"2022-08-08 15:00:24","TRT01SDTM":"2019-08-08 21:00:24","TRT01EDTM":"2021-08-08 09:00:24","TRT02SDTM":"2021-08-08 09:00:24","TRT02EDTM":"2022-08-08 15:00:24","AP01SDTM":"2019-08-08 21:00:24","AP01EDTM":"2021-08-08 09:00:24","AP02SDTM":"2021-08-08 09:00:24","AP02EDTM":"2022-08-08 15:00:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-08","EOSDY":1096,"LSTALVDT":"2022-08-29","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3417,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.28276,"AVALU":"mg/L","BASE2":7.71572,"BASE":9.98156,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.56705,"PCHG2":7.34922,"CHG":-1.6988,"PCHG":-17.0194,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-24 21:00:24","ADY":1051,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-204","SUBJID":"id-204","SITEID":"CHN-3","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.68264,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-06","TRTSDTM":"2019-08-08 21:00:24","TRTEDTM":"2022-08-08 15:00:24","TRT01SDTM":"2019-08-08 21:00:24","TRT01EDTM":"2021-08-08 09:00:24","TRT02SDTM":"2021-08-08 09:00:24","TRT02EDTM":"2022-08-08 15:00:24","AP01SDTM":"2019-08-08 21:00:24","AP01EDTM":"2021-08-08 09:00:24","AP02SDTM":"2021-08-08 09:00:24","AP02EDTM":"2022-08-08 15:00:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-08","EOSDY":1096,"LSTALVDT":"2022-08-29","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3289,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7638,"AVALU":"g/L","BASE2":2.7638,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-06-08 21:00:24","ADY":670,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-204","SUBJID":"id-204","SITEID":"CHN-3","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.68264,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-06","TRTSDTM":"2019-08-08 21:00:24","TRTEDTM":"2022-08-08 15:00:24","TRT01SDTM":"2019-08-08 21:00:24","TRT01EDTM":"2021-08-08 09:00:24","TRT02SDTM":"2021-08-08 09:00:24","TRT02EDTM":"2022-08-08 15:00:24","AP01SDTM":"2019-08-08 21:00:24","AP01EDTM":"2021-08-08 09:00:24","AP02SDTM":"2021-08-08 09:00:24","AP02EDTM":"2022-08-08 15:00:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-08","EOSDY":1096,"LSTALVDT":"2022-08-29","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1705,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03581,"AVALU":"g/L","BASE2":2.7638,"BASE":3.03581,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.27201,"PCHG2":9.84201,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2021-09-14 21:00:24","ADY":768,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-204","SUBJID":"id-204","SITEID":"CHN-3","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.68264,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-06","TRTSDTM":"2019-08-08 21:00:24","TRTEDTM":"2022-08-08 15:00:24","TRT01SDTM":"2019-08-08 21:00:24","TRT01EDTM":"2021-08-08 09:00:24","TRT02SDTM":"2021-08-08 09:00:24","TRT02EDTM":"2022-08-08 15:00:24","AP01SDTM":"2019-08-08 21:00:24","AP01EDTM":"2021-08-08 09:00:24","AP02SDTM":"2021-08-08 09:00:24","AP02EDTM":"2022-08-08 15:00:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-08","EOSDY":1096,"LSTALVDT":"2022-08-29","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3239,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99284,"AVALU":"g/L","BASE2":2.7638,"BASE":3.03581,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.22904,"PCHG2":8.28704,"CHG":-0.04298,"PCHG":-1.41565,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-10-04 21:00:24","ADY":788,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-204","SUBJID":"id-204","SITEID":"CHN-3","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.68264,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-06","TRTSDTM":"2019-08-08 21:00:24","TRTEDTM":"2022-08-08 15:00:24","TRT01SDTM":"2019-08-08 21:00:24","TRT01EDTM":"2021-08-08 09:00:24","TRT02SDTM":"2021-08-08 09:00:24","TRT02EDTM":"2022-08-08 15:00:24","AP01SDTM":"2019-08-08 21:00:24","AP01EDTM":"2021-08-08 09:00:24","AP02SDTM":"2021-08-08 09:00:24","AP02EDTM":"2022-08-08 15:00:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-08","EOSDY":1096,"LSTALVDT":"2022-08-29","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6536,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74474,"AVALU":"g/L","BASE2":2.7638,"BASE":3.03581,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01906,"PCHG2":-0.68972,"CHG":-0.29108,"PCHG":-9.58807,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-04-28 21:00:24","ADY":994,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-204","SUBJID":"id-204","SITEID":"CHN-3","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.68264,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-06","TRTSDTM":"2019-08-08 21:00:24","TRTEDTM":"2022-08-08 15:00:24","TRT01SDTM":"2019-08-08 21:00:24","TRT01EDTM":"2021-08-08 09:00:24","TRT02SDTM":"2021-08-08 09:00:24","TRT02EDTM":"2022-08-08 15:00:24","AP01SDTM":"2019-08-08 21:00:24","AP01EDTM":"2021-08-08 09:00:24","AP02SDTM":"2021-08-08 09:00:24","AP02EDTM":"2022-08-08 15:00:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-08","EOSDY":1096,"LSTALVDT":"2022-08-29","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8084,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9408,"AVALU":"g/L","BASE2":2.7638,"BASE":3.03581,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.177,"PCHG2":6.40428,"CHG":-0.09501,"PCHG":-3.12971,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-05-02 21:00:24","ADY":998,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-204","SUBJID":"id-204","SITEID":"CHN-3","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.68264,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-06","TRTSDTM":"2019-08-08 21:00:24","TRTEDTM":"2022-08-08 15:00:24","TRT01SDTM":"2019-08-08 21:00:24","TRT01EDTM":"2021-08-08 09:00:24","TRT02SDTM":"2021-08-08 09:00:24","TRT02EDTM":"2022-08-08 15:00:24","AP01SDTM":"2019-08-08 21:00:24","AP01EDTM":"2021-08-08 09:00:24","AP02SDTM":"2021-08-08 09:00:24","AP02EDTM":"2022-08-08 15:00:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-08","EOSDY":1096,"LSTALVDT":"2022-08-29","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4760,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88026,"AVALU":"g/L","BASE2":2.7638,"BASE":3.03581,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11646,"PCHG2":4.21366,"CHG":-0.15556,"PCHG":-5.12404,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-05-18 21:00:24","ADY":1014,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-204","SUBJID":"id-204","SITEID":"CHN-3","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.68264,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-06","TRTSDTM":"2019-08-08 21:00:24","TRTEDTM":"2022-08-08 15:00:24","TRT01SDTM":"2019-08-08 21:00:24","TRT01EDTM":"2021-08-08 09:00:24","TRT02SDTM":"2021-08-08 09:00:24","TRT02EDTM":"2022-08-08 15:00:24","AP01SDTM":"2019-08-08 21:00:24","AP01EDTM":"2021-08-08 09:00:24","AP02SDTM":"2021-08-08 09:00:24","AP02EDTM":"2022-08-08 15:00:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-08","EOSDY":1096,"LSTALVDT":"2022-08-29","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":343,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88726,"AVALU":"g/L","BASE2":2.7638,"BASE":3.03581,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12346,"PCHG2":4.467,"CHG":-0.14855,"PCHG":-4.89341,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-06-24 21:00:24","ADY":1051,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-259","SUBJID":"id-259","SITEID":"CHN-3","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.3313,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-04","TRTSDTM":"2019-08-07 07:18:48","TRTEDTM":"2022-08-07 01:18:48","TRT01SDTM":"2019-08-07 07:18:48","TRT01EDTM":"2021-08-06 19:18:48","TRT02SDTM":"2021-08-06 19:18:48","TRT02EDTM":"2022-08-07 01:18:48","AP01SDTM":"2019-08-07 07:18:48","AP01EDTM":"2021-08-06 19:18:48","AP02SDTM":"2021-08-06 19:18:48","AP02EDTM":"2022-08-07 01:18:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-07","EOSDY":1096,"LSTALVDT":"2022-08-18","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":986,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.74341,"AVALU":"U/L","BASE2":18.74341,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-31 07:18:48","ADY":146,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-259","SUBJID":"id-259","SITEID":"CHN-3","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.3313,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-04","TRTSDTM":"2019-08-07 07:18:48","TRTEDTM":"2022-08-07 01:18:48","TRT01SDTM":"2019-08-07 07:18:48","TRT01EDTM":"2021-08-06 19:18:48","TRT02SDTM":"2021-08-06 19:18:48","TRT02EDTM":"2022-08-07 01:18:48","AP01SDTM":"2019-08-07 07:18:48","AP01EDTM":"2021-08-06 19:18:48","AP02SDTM":"2021-08-06 19:18:48","AP02EDTM":"2022-08-07 01:18:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-07","EOSDY":1096,"LSTALVDT":"2022-08-18","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7068,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.61341,"AVALU":"U/L","BASE2":18.74341,"BASE":18.61341,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.13,"PCHG2":-0.69357,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-13 07:18:48","ADY":494,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-259","SUBJID":"id-259","SITEID":"CHN-3","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.3313,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-04","TRTSDTM":"2019-08-07 07:18:48","TRTEDTM":"2022-08-07 01:18:48","TRT01SDTM":"2019-08-07 07:18:48","TRT01EDTM":"2021-08-06 19:18:48","TRT02SDTM":"2021-08-06 19:18:48","TRT02EDTM":"2022-08-07 01:18:48","AP01SDTM":"2019-08-07 07:18:48","AP01EDTM":"2021-08-06 19:18:48","AP02SDTM":"2021-08-06 19:18:48","AP02EDTM":"2022-08-07 01:18:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-07","EOSDY":1096,"LSTALVDT":"2022-08-18","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5386,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.73041,"AVALU":"U/L","BASE2":18.74341,"BASE":18.61341,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01301,"PCHG2":-0.06939,"CHG":0.11699,"PCHG":0.62854,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-14 07:18:48","ADY":616,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-259","SUBJID":"id-259","SITEID":"CHN-3","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.3313,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-04","TRTSDTM":"2019-08-07 07:18:48","TRTEDTM":"2022-08-07 01:18:48","TRT01SDTM":"2019-08-07 07:18:48","TRT01EDTM":"2021-08-06 19:18:48","TRT02SDTM":"2021-08-06 19:18:48","TRT02EDTM":"2022-08-07 01:18:48","AP01SDTM":"2019-08-07 07:18:48","AP01EDTM":"2021-08-06 19:18:48","AP02SDTM":"2021-08-06 19:18:48","AP02EDTM":"2022-08-07 01:18:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-07","EOSDY":1096,"LSTALVDT":"2022-08-18","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8220,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.18571,"AVALU":"U/L","BASE2":18.74341,"BASE":18.61341,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.44229,"PCHG2":13.03015,"CHG":2.57229,"PCHG":13.81956,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-15 07:18:48","ADY":647,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-259","SUBJID":"id-259","SITEID":"CHN-3","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.3313,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-04","TRTSDTM":"2019-08-07 07:18:48","TRTEDTM":"2022-08-07 01:18:48","TRT01SDTM":"2019-08-07 07:18:48","TRT01EDTM":"2021-08-06 19:18:48","TRT02SDTM":"2021-08-06 19:18:48","TRT02EDTM":"2022-08-07 01:18:48","AP01SDTM":"2019-08-07 07:18:48","AP01EDTM":"2021-08-06 19:18:48","AP02SDTM":"2021-08-06 19:18:48","AP02EDTM":"2022-08-07 01:18:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-07","EOSDY":1096,"LSTALVDT":"2022-08-18","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3074,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.47879,"AVALU":"U/L","BASE2":18.74341,"BASE":18.61341,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-18.26462,"PCHG2":-97.44556,"CHG":-18.13463,"PCHG":-97.42772,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-08-30 07:18:48","ADY":754,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-259","SUBJID":"id-259","SITEID":"CHN-3","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.3313,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-04","TRTSDTM":"2019-08-07 07:18:48","TRTEDTM":"2022-08-07 01:18:48","TRT01SDTM":"2019-08-07 07:18:48","TRT01EDTM":"2021-08-06 19:18:48","TRT02SDTM":"2021-08-06 19:18:48","TRT02EDTM":"2022-08-07 01:18:48","AP01SDTM":"2019-08-07 07:18:48","AP01EDTM":"2021-08-06 19:18:48","AP02SDTM":"2021-08-06 19:18:48","AP02EDTM":"2022-08-07 01:18:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-07","EOSDY":1096,"LSTALVDT":"2022-08-18","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7121,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.21963,"AVALU":"U/L","BASE2":18.74341,"BASE":18.61341,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.47622,"PCHG2":45.2224,"CHG":8.60622,"PCHG":46.23665,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-20 07:18:48","ADY":866,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-259","SUBJID":"id-259","SITEID":"CHN-3","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.3313,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-04","TRTSDTM":"2019-08-07 07:18:48","TRTEDTM":"2022-08-07 01:18:48","TRT01SDTM":"2019-08-07 07:18:48","TRT01EDTM":"2021-08-06 19:18:48","TRT02SDTM":"2021-08-06 19:18:48","TRT02EDTM":"2022-08-07 01:18:48","AP01SDTM":"2019-08-07 07:18:48","AP01EDTM":"2021-08-06 19:18:48","AP02SDTM":"2021-08-06 19:18:48","AP02EDTM":"2022-08-07 01:18:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-07","EOSDY":1096,"LSTALVDT":"2022-08-18","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5327,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.7634,"AVALU":"U/L","BASE2":18.74341,"BASE":18.61341,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.01999,"PCHG2":74.79955,"CHG":14.14999,"PCHG":76.02037,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-22 07:18:48","ADY":989,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-259","SUBJID":"id-259","SITEID":"CHN-3","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.3313,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-04","TRTSDTM":"2019-08-07 07:18:48","TRTEDTM":"2022-08-07 01:18:48","TRT01SDTM":"2019-08-07 07:18:48","TRT01EDTM":"2021-08-06 19:18:48","TRT02SDTM":"2021-08-06 19:18:48","TRT02EDTM":"2022-08-07 01:18:48","AP01SDTM":"2019-08-07 07:18:48","AP01EDTM":"2021-08-06 19:18:48","AP02SDTM":"2021-08-06 19:18:48","AP02EDTM":"2022-08-07 01:18:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-07","EOSDY":1096,"LSTALVDT":"2022-08-18","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6905,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.21849,"AVALU":"mg/L","BASE2":9.21849,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-31 07:18:48","ADY":146,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-259","SUBJID":"id-259","SITEID":"CHN-3","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.3313,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-04","TRTSDTM":"2019-08-07 07:18:48","TRTEDTM":"2022-08-07 01:18:48","TRT01SDTM":"2019-08-07 07:18:48","TRT01EDTM":"2021-08-06 19:18:48","TRT02SDTM":"2021-08-06 19:18:48","TRT02EDTM":"2022-08-07 01:18:48","AP01SDTM":"2019-08-07 07:18:48","AP01EDTM":"2021-08-06 19:18:48","AP02SDTM":"2021-08-06 19:18:48","AP02EDTM":"2022-08-07 01:18:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-07","EOSDY":1096,"LSTALVDT":"2022-08-18","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":365,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.83203,"AVALU":"mg/L","BASE2":9.21849,"BASE":9.83203,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.61354,"PCHG2":6.65557,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-13 07:18:48","ADY":494,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-259","SUBJID":"id-259","SITEID":"CHN-3","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.3313,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-04","TRTSDTM":"2019-08-07 07:18:48","TRTEDTM":"2022-08-07 01:18:48","TRT01SDTM":"2019-08-07 07:18:48","TRT01EDTM":"2021-08-06 19:18:48","TRT02SDTM":"2021-08-06 19:18:48","TRT02EDTM":"2022-08-07 01:18:48","AP01SDTM":"2019-08-07 07:18:48","AP01EDTM":"2021-08-06 19:18:48","AP02SDTM":"2021-08-06 19:18:48","AP02EDTM":"2022-08-07 01:18:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-07","EOSDY":1096,"LSTALVDT":"2022-08-18","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6560,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.60187,"AVALU":"mg/L","BASE2":9.21849,"BASE":9.83203,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.38338,"PCHG2":4.15881,"CHG":-0.23016,"PCHG":-2.34096,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-14 07:18:48","ADY":616,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-259","SUBJID":"id-259","SITEID":"CHN-3","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.3313,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-04","TRTSDTM":"2019-08-07 07:18:48","TRTEDTM":"2022-08-07 01:18:48","TRT01SDTM":"2019-08-07 07:18:48","TRT01EDTM":"2021-08-06 19:18:48","TRT02SDTM":"2021-08-06 19:18:48","TRT02EDTM":"2022-08-07 01:18:48","AP01SDTM":"2019-08-07 07:18:48","AP01EDTM":"2021-08-06 19:18:48","AP02SDTM":"2021-08-06 19:18:48","AP02EDTM":"2022-08-07 01:18:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-07","EOSDY":1096,"LSTALVDT":"2022-08-18","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4195,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.36821,"AVALU":"mg/L","BASE2":9.21849,"BASE":9.83203,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.85028,"PCHG2":-9.22366,"CHG":-1.46382,"PCHG":-14.88832,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-15 07:18:48","ADY":647,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-259","SUBJID":"id-259","SITEID":"CHN-3","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.3313,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-04","TRTSDTM":"2019-08-07 07:18:48","TRTEDTM":"2022-08-07 01:18:48","TRT01SDTM":"2019-08-07 07:18:48","TRT01EDTM":"2021-08-06 19:18:48","TRT02SDTM":"2021-08-06 19:18:48","TRT02EDTM":"2022-08-07 01:18:48","AP01SDTM":"2019-08-07 07:18:48","AP01EDTM":"2021-08-06 19:18:48","AP02SDTM":"2021-08-06 19:18:48","AP02EDTM":"2022-08-07 01:18:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-07","EOSDY":1096,"LSTALVDT":"2022-08-18","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7969,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.26733,"AVALU":"mg/L","BASE2":9.21849,"BASE":9.83203,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.95116,"PCHG2":-10.31793,"CHG":-1.5647,"PCHG":-15.91431,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-30 07:18:48","ADY":754,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-259","SUBJID":"id-259","SITEID":"CHN-3","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.3313,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-04","TRTSDTM":"2019-08-07 07:18:48","TRTEDTM":"2022-08-07 01:18:48","TRT01SDTM":"2019-08-07 07:18:48","TRT01EDTM":"2021-08-06 19:18:48","TRT02SDTM":"2021-08-06 19:18:48","TRT02EDTM":"2022-08-07 01:18:48","AP01SDTM":"2019-08-07 07:18:48","AP01EDTM":"2021-08-06 19:18:48","AP02SDTM":"2021-08-06 19:18:48","AP02EDTM":"2022-08-07 01:18:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-07","EOSDY":1096,"LSTALVDT":"2022-08-18","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4403,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.22202,"AVALU":"mg/L","BASE2":9.21849,"BASE":9.83203,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.00354,"PCHG2":21.73391,"CHG":1.38999,"PCHG":14.13741,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-12-20 07:18:48","ADY":866,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-259","SUBJID":"id-259","SITEID":"CHN-3","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.3313,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-04","TRTSDTM":"2019-08-07 07:18:48","TRTEDTM":"2022-08-07 01:18:48","TRT01SDTM":"2019-08-07 07:18:48","TRT01EDTM":"2021-08-06 19:18:48","TRT02SDTM":"2021-08-06 19:18:48","TRT02EDTM":"2022-08-07 01:18:48","AP01SDTM":"2019-08-07 07:18:48","AP01EDTM":"2021-08-06 19:18:48","AP02SDTM":"2021-08-06 19:18:48","AP02EDTM":"2022-08-07 01:18:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-07","EOSDY":1096,"LSTALVDT":"2022-08-18","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":195,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.9862,"AVALU":"mg/L","BASE2":9.21849,"BASE":9.83203,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.23229,"PCHG2":-2.51977,"CHG":-0.84583,"PCHG":-8.60278,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-22 07:18:48","ADY":989,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-259","SUBJID":"id-259","SITEID":"CHN-3","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.3313,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-04","TRTSDTM":"2019-08-07 07:18:48","TRTEDTM":"2022-08-07 01:18:48","TRT01SDTM":"2019-08-07 07:18:48","TRT01EDTM":"2021-08-06 19:18:48","TRT02SDTM":"2021-08-06 19:18:48","TRT02EDTM":"2022-08-07 01:18:48","AP01SDTM":"2019-08-07 07:18:48","AP01EDTM":"2021-08-06 19:18:48","AP02SDTM":"2021-08-06 19:18:48","AP02EDTM":"2022-08-07 01:18:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-07","EOSDY":1096,"LSTALVDT":"2022-08-18","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2814,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99337,"AVALU":"g/L","BASE2":2.99337,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-31 07:18:48","ADY":146,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-259","SUBJID":"id-259","SITEID":"CHN-3","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.3313,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-04","TRTSDTM":"2019-08-07 07:18:48","TRTEDTM":"2022-08-07 01:18:48","TRT01SDTM":"2019-08-07 07:18:48","TRT01EDTM":"2021-08-06 19:18:48","TRT02SDTM":"2021-08-06 19:18:48","TRT02EDTM":"2022-08-07 01:18:48","AP01SDTM":"2019-08-07 07:18:48","AP01EDTM":"2021-08-06 19:18:48","AP02SDTM":"2021-08-06 19:18:48","AP02EDTM":"2022-08-07 01:18:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-07","EOSDY":1096,"LSTALVDT":"2022-08-18","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3621,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92255,"AVALU":"g/L","BASE2":2.99337,"BASE":2.92255,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.07083,"PCHG2":-2.36608,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-13 07:18:48","ADY":494,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-259","SUBJID":"id-259","SITEID":"CHN-3","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.3313,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-04","TRTSDTM":"2019-08-07 07:18:48","TRTEDTM":"2022-08-07 01:18:48","TRT01SDTM":"2019-08-07 07:18:48","TRT01EDTM":"2021-08-06 19:18:48","TRT02SDTM":"2021-08-06 19:18:48","TRT02EDTM":"2022-08-07 01:18:48","AP01SDTM":"2019-08-07 07:18:48","AP01EDTM":"2021-08-06 19:18:48","AP02SDTM":"2021-08-06 19:18:48","AP02EDTM":"2022-08-07 01:18:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-07","EOSDY":1096,"LSTALVDT":"2022-08-18","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3991,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82194,"AVALU":"g/L","BASE2":2.99337,"BASE":2.92255,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17143,"PCHG2":-5.72713,"CHG":-0.10061,"PCHG":-3.4425,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-14 07:18:48","ADY":616,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-259","SUBJID":"id-259","SITEID":"CHN-3","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.3313,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-04","TRTSDTM":"2019-08-07 07:18:48","TRTEDTM":"2022-08-07 01:18:48","TRT01SDTM":"2019-08-07 07:18:48","TRT01EDTM":"2021-08-06 19:18:48","TRT02SDTM":"2021-08-06 19:18:48","TRT02EDTM":"2022-08-07 01:18:48","AP01SDTM":"2019-08-07 07:18:48","AP01EDTM":"2021-08-06 19:18:48","AP02SDTM":"2021-08-06 19:18:48","AP02EDTM":"2022-08-07 01:18:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-07","EOSDY":1096,"LSTALVDT":"2022-08-18","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5612,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00662,"AVALU":"g/L","BASE2":2.99337,"BASE":2.92255,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01325,"PCHG2":0.44263,"CHG":0.08407,"PCHG":2.87677,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-05-15 07:18:48","ADY":647,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-259","SUBJID":"id-259","SITEID":"CHN-3","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.3313,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-04","TRTSDTM":"2019-08-07 07:18:48","TRTEDTM":"2022-08-07 01:18:48","TRT01SDTM":"2019-08-07 07:18:48","TRT01EDTM":"2021-08-06 19:18:48","TRT02SDTM":"2021-08-06 19:18:48","TRT02EDTM":"2022-08-07 01:18:48","AP01SDTM":"2019-08-07 07:18:48","AP01EDTM":"2021-08-06 19:18:48","AP02SDTM":"2021-08-06 19:18:48","AP02EDTM":"2022-08-07 01:18:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-07","EOSDY":1096,"LSTALVDT":"2022-08-18","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3287,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88094,"AVALU":"g/L","BASE2":2.99337,"BASE":2.92255,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11243,"PCHG2":-3.75602,"CHG":-0.04161,"PCHG":-1.42362,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-30 07:18:48","ADY":754,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-259","SUBJID":"id-259","SITEID":"CHN-3","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.3313,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-04","TRTSDTM":"2019-08-07 07:18:48","TRTEDTM":"2022-08-07 01:18:48","TRT01SDTM":"2019-08-07 07:18:48","TRT01EDTM":"2021-08-06 19:18:48","TRT02SDTM":"2021-08-06 19:18:48","TRT02EDTM":"2022-08-07 01:18:48","AP01SDTM":"2019-08-07 07:18:48","AP01EDTM":"2021-08-06 19:18:48","AP02SDTM":"2021-08-06 19:18:48","AP02EDTM":"2022-08-07 01:18:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-07","EOSDY":1096,"LSTALVDT":"2022-08-18","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6588,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0373,"AVALU":"g/L","BASE2":2.99337,"BASE":2.92255,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04393,"PCHG2":1.46764,"CHG":0.11476,"PCHG":3.92663,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-12-20 07:18:48","ADY":866,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-259","SUBJID":"id-259","SITEID":"CHN-3","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.3313,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-04","TRTSDTM":"2019-08-07 07:18:48","TRTEDTM":"2022-08-07 01:18:48","TRT01SDTM":"2019-08-07 07:18:48","TRT01EDTM":"2021-08-06 19:18:48","TRT02SDTM":"2021-08-06 19:18:48","TRT02EDTM":"2022-08-07 01:18:48","AP01SDTM":"2019-08-07 07:18:48","AP01EDTM":"2021-08-06 19:18:48","AP02SDTM":"2021-08-06 19:18:48","AP02EDTM":"2022-08-07 01:18:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-07","EOSDY":1096,"LSTALVDT":"2022-08-18","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5680,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94077,"AVALU":"g/L","BASE2":2.99337,"BASE":2.92255,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0526,"PCHG2":-1.75723,"CHG":0.01823,"PCHG":0.6236,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-22 07:18:48","ADY":989,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-271","SUBJID":"id-271","SITEID":"CHN-3","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.80752,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-04","TRTSDTM":"2020-08-06 02:22:10","TRTEDTM":"2023-08-06 20:22:10","TRT01SDTM":"2020-08-06 02:22:10","TRT01EDTM":"2022-08-06 14:22:10","TRT02SDTM":"2022-08-06 14:22:10","TRT02EDTM":"2023-08-06 20:22:10","AP01SDTM":"2020-08-06 02:22:10","AP01EDTM":"2022-08-06 14:22:10","AP02SDTM":"2022-08-06 14:22:10","AP02EDTM":"2023-08-06 20:22:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1258,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.44165,"AVALU":"U/L","BASE2":20.44165,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-08 02:22:10","ADY":245,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-271","SUBJID":"id-271","SITEID":"CHN-3","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.80752,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-04","TRTSDTM":"2020-08-06 02:22:10","TRTEDTM":"2023-08-06 20:22:10","TRT01SDTM":"2020-08-06 02:22:10","TRT01EDTM":"2022-08-06 14:22:10","TRT02SDTM":"2022-08-06 14:22:10","TRT02EDTM":"2023-08-06 20:22:10","AP01SDTM":"2020-08-06 02:22:10","AP01EDTM":"2022-08-06 14:22:10","AP02SDTM":"2022-08-06 14:22:10","AP02EDTM":"2023-08-06 20:22:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2111,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.11912,"AVALU":"U/L","BASE2":20.44165,"BASE":14.11912,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-6.32253,"PCHG2":-30.92966,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-09 02:22:10","ADY":552,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-271","SUBJID":"id-271","SITEID":"CHN-3","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.80752,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-04","TRTSDTM":"2020-08-06 02:22:10","TRTEDTM":"2023-08-06 20:22:10","TRT01SDTM":"2020-08-06 02:22:10","TRT01EDTM":"2022-08-06 14:22:10","TRT02SDTM":"2022-08-06 14:22:10","TRT02EDTM":"2023-08-06 20:22:10","AP01SDTM":"2020-08-06 02:22:10","AP01EDTM":"2022-08-06 14:22:10","AP02SDTM":"2022-08-06 14:22:10","AP02EDTM":"2023-08-06 20:22:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6659,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.62667,"AVALU":"U/L","BASE2":20.44165,"BASE":14.11912,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.81498,"PCHG2":-33.3387,"CHG":-0.49245,"PCHG":-3.48782,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-20 02:22:10","ADY":622,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-271","SUBJID":"id-271","SITEID":"CHN-3","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.80752,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-04","TRTSDTM":"2020-08-06 02:22:10","TRTEDTM":"2023-08-06 20:22:10","TRT01SDTM":"2020-08-06 02:22:10","TRT01EDTM":"2022-08-06 14:22:10","TRT02SDTM":"2022-08-06 14:22:10","TRT02EDTM":"2023-08-06 20:22:10","AP01SDTM":"2020-08-06 02:22:10","AP01EDTM":"2022-08-06 14:22:10","AP02SDTM":"2022-08-06 14:22:10","AP02EDTM":"2023-08-06 20:22:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5401,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.17845,"AVALU":"U/L","BASE2":20.44165,"BASE":14.11912,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.7368,"PCHG2":32.95626,"CHG":13.05933,"PCHG":92.49398,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-12 02:22:10","ADY":797,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-271","SUBJID":"id-271","SITEID":"CHN-3","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.80752,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-04","TRTSDTM":"2020-08-06 02:22:10","TRTEDTM":"2023-08-06 20:22:10","TRT01SDTM":"2020-08-06 02:22:10","TRT01EDTM":"2022-08-06 14:22:10","TRT02SDTM":"2022-08-06 14:22:10","TRT02EDTM":"2023-08-06 20:22:10","AP01SDTM":"2020-08-06 02:22:10","AP01EDTM":"2022-08-06 14:22:10","AP02SDTM":"2022-08-06 14:22:10","AP02EDTM":"2023-08-06 20:22:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2428,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.72605,"AVALU":"U/L","BASE2":20.44165,"BASE":14.11912,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.7156,"PCHG2":-27.96054,"CHG":0.60694,"PCHG":4.29868,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-19 02:22:10","ADY":927,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-271","SUBJID":"id-271","SITEID":"CHN-3","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.80752,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-04","TRTSDTM":"2020-08-06 02:22:10","TRTEDTM":"2023-08-06 20:22:10","TRT01SDTM":"2020-08-06 02:22:10","TRT01EDTM":"2022-08-06 14:22:10","TRT02SDTM":"2022-08-06 14:22:10","TRT02EDTM":"2023-08-06 20:22:10","AP01SDTM":"2020-08-06 02:22:10","AP01EDTM":"2022-08-06 14:22:10","AP02SDTM":"2022-08-06 14:22:10","AP02EDTM":"2023-08-06 20:22:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2436,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.99655,"AVALU":"U/L","BASE2":20.44165,"BASE":14.11912,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.4451,"PCHG2":-7.06938,"CHG":4.87743,"PCHG":34.5449,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-22 02:22:10","ADY":958,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-271","SUBJID":"id-271","SITEID":"CHN-3","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.80752,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-04","TRTSDTM":"2020-08-06 02:22:10","TRTEDTM":"2023-08-06 20:22:10","TRT01SDTM":"2020-08-06 02:22:10","TRT01EDTM":"2022-08-06 14:22:10","TRT02SDTM":"2022-08-06 14:22:10","TRT02EDTM":"2023-08-06 20:22:10","AP01SDTM":"2020-08-06 02:22:10","AP01EDTM":"2022-08-06 14:22:10","AP02SDTM":"2022-08-06 14:22:10","AP02EDTM":"2023-08-06 20:22:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2957,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.30912,"AVALU":"U/L","BASE2":20.44165,"BASE":14.11912,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.13253,"PCHG2":-34.89214,"CHG":-0.81,"PCHG":-5.73688,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-12 02:22:10","ADY":979,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-271","SUBJID":"id-271","SITEID":"CHN-3","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.80752,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-04","TRTSDTM":"2020-08-06 02:22:10","TRTEDTM":"2023-08-06 20:22:10","TRT01SDTM":"2020-08-06 02:22:10","TRT01EDTM":"2022-08-06 14:22:10","TRT02SDTM":"2022-08-06 14:22:10","TRT02EDTM":"2023-08-06 20:22:10","AP01SDTM":"2020-08-06 02:22:10","AP01EDTM":"2022-08-06 14:22:10","AP02SDTM":"2022-08-06 14:22:10","AP02EDTM":"2023-08-06 20:22:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6957,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.01872,"AVALU":"mg/L","BASE2":9.01872,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-08 02:22:10","ADY":245,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-271","SUBJID":"id-271","SITEID":"CHN-3","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.80752,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-04","TRTSDTM":"2020-08-06 02:22:10","TRTEDTM":"2023-08-06 20:22:10","TRT01SDTM":"2020-08-06 02:22:10","TRT01EDTM":"2022-08-06 14:22:10","TRT02SDTM":"2022-08-06 14:22:10","TRT02EDTM":"2023-08-06 20:22:10","AP01SDTM":"2020-08-06 02:22:10","AP01EDTM":"2022-08-06 14:22:10","AP02SDTM":"2022-08-06 14:22:10","AP02EDTM":"2023-08-06 20:22:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3552,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.5057,"AVALU":"mg/L","BASE2":9.01872,"BASE":8.5057,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.51302,"PCHG2":-5.68837,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-09 02:22:10","ADY":552,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-271","SUBJID":"id-271","SITEID":"CHN-3","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.80752,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-04","TRTSDTM":"2020-08-06 02:22:10","TRTEDTM":"2023-08-06 20:22:10","TRT01SDTM":"2020-08-06 02:22:10","TRT01EDTM":"2022-08-06 14:22:10","TRT02SDTM":"2022-08-06 14:22:10","TRT02EDTM":"2023-08-06 20:22:10","AP01SDTM":"2020-08-06 02:22:10","AP01EDTM":"2022-08-06 14:22:10","AP02SDTM":"2022-08-06 14:22:10","AP02EDTM":"2023-08-06 20:22:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4819,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.49886,"AVALU":"mg/L","BASE2":9.01872,"BASE":8.5057,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.48014,"PCHG2":16.41185,"CHG":1.99316,"PCHG":23.43318,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-04-20 02:22:10","ADY":622,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-271","SUBJID":"id-271","SITEID":"CHN-3","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.80752,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-04","TRTSDTM":"2020-08-06 02:22:10","TRTEDTM":"2023-08-06 20:22:10","TRT01SDTM":"2020-08-06 02:22:10","TRT01EDTM":"2022-08-06 14:22:10","TRT02SDTM":"2022-08-06 14:22:10","TRT02EDTM":"2023-08-06 20:22:10","AP01SDTM":"2020-08-06 02:22:10","AP01EDTM":"2022-08-06 14:22:10","AP02SDTM":"2022-08-06 14:22:10","AP02EDTM":"2023-08-06 20:22:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2498,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.26138,"AVALU":"mg/L","BASE2":9.01872,"BASE":8.5057,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.24266,"PCHG2":2.69065,"CHG":0.75568,"PCHG":8.8844,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-12 02:22:10","ADY":797,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-271","SUBJID":"id-271","SITEID":"CHN-3","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.80752,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-04","TRTSDTM":"2020-08-06 02:22:10","TRTEDTM":"2023-08-06 20:22:10","TRT01SDTM":"2020-08-06 02:22:10","TRT01EDTM":"2022-08-06 14:22:10","TRT02SDTM":"2022-08-06 14:22:10","TRT02EDTM":"2023-08-06 20:22:10","AP01SDTM":"2020-08-06 02:22:10","AP01EDTM":"2022-08-06 14:22:10","AP02SDTM":"2022-08-06 14:22:10","AP02EDTM":"2023-08-06 20:22:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6202,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.45118,"AVALU":"mg/L","BASE2":9.01872,"BASE":8.5057,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.56754,"PCHG2":-6.29287,"CHG":-0.05452,"PCHG":-0.64097,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-19 02:22:10","ADY":927,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-271","SUBJID":"id-271","SITEID":"CHN-3","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.80752,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-04","TRTSDTM":"2020-08-06 02:22:10","TRTEDTM":"2023-08-06 20:22:10","TRT01SDTM":"2020-08-06 02:22:10","TRT01EDTM":"2022-08-06 14:22:10","TRT02SDTM":"2022-08-06 14:22:10","TRT02EDTM":"2023-08-06 20:22:10","AP01SDTM":"2020-08-06 02:22:10","AP01EDTM":"2022-08-06 14:22:10","AP02SDTM":"2022-08-06 14:22:10","AP02EDTM":"2023-08-06 20:22:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1494,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.53936,"AVALU":"mg/L","BASE2":9.01872,"BASE":8.5057,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.47935,"PCHG2":-16.40316,"CHG":-0.96634,"PCHG":-11.36105,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2023-03-22 02:22:10","ADY":958,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-271","SUBJID":"id-271","SITEID":"CHN-3","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.80752,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-04","TRTSDTM":"2020-08-06 02:22:10","TRTEDTM":"2023-08-06 20:22:10","TRT01SDTM":"2020-08-06 02:22:10","TRT01EDTM":"2022-08-06 14:22:10","TRT02SDTM":"2022-08-06 14:22:10","TRT02EDTM":"2023-08-06 20:22:10","AP01SDTM":"2020-08-06 02:22:10","AP01EDTM":"2022-08-06 14:22:10","AP02SDTM":"2022-08-06 14:22:10","AP02EDTM":"2023-08-06 20:22:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5786,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.28172,"AVALU":"mg/L","BASE2":9.01872,"BASE":8.5057,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.26301,"PCHG2":2.91623,"CHG":0.77602,"PCHG":9.12358,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-12 02:22:10","ADY":979,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-271","SUBJID":"id-271","SITEID":"CHN-3","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.80752,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-04","TRTSDTM":"2020-08-06 02:22:10","TRTEDTM":"2023-08-06 20:22:10","TRT01SDTM":"2020-08-06 02:22:10","TRT01EDTM":"2022-08-06 14:22:10","TRT02SDTM":"2022-08-06 14:22:10","TRT02EDTM":"2023-08-06 20:22:10","AP01SDTM":"2020-08-06 02:22:10","AP01EDTM":"2022-08-06 14:22:10","AP02SDTM":"2022-08-06 14:22:10","AP02EDTM":"2023-08-06 20:22:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5278,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91665,"AVALU":"g/L","BASE2":2.91665,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-08 02:22:10","ADY":245,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-271","SUBJID":"id-271","SITEID":"CHN-3","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.80752,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-04","TRTSDTM":"2020-08-06 02:22:10","TRTEDTM":"2023-08-06 20:22:10","TRT01SDTM":"2020-08-06 02:22:10","TRT01EDTM":"2022-08-06 14:22:10","TRT02SDTM":"2022-08-06 14:22:10","TRT02EDTM":"2023-08-06 20:22:10","AP01SDTM":"2020-08-06 02:22:10","AP01EDTM":"2022-08-06 14:22:10","AP02SDTM":"2022-08-06 14:22:10","AP02EDTM":"2023-08-06 20:22:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2778,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90458,"AVALU":"g/L","BASE2":2.91665,"BASE":2.90458,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.01207,"PCHG2":-0.41367,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-09 02:22:10","ADY":552,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-271","SUBJID":"id-271","SITEID":"CHN-3","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.80752,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-04","TRTSDTM":"2020-08-06 02:22:10","TRTEDTM":"2023-08-06 20:22:10","TRT01SDTM":"2020-08-06 02:22:10","TRT01EDTM":"2022-08-06 14:22:10","TRT02SDTM":"2022-08-06 14:22:10","TRT02EDTM":"2023-08-06 20:22:10","AP01SDTM":"2020-08-06 02:22:10","AP01EDTM":"2022-08-06 14:22:10","AP02SDTM":"2022-08-06 14:22:10","AP02EDTM":"2023-08-06 20:22:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5351,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02004,"AVALU":"g/L","BASE2":2.91665,"BASE":2.90458,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10339,"PCHG2":3.54475,"CHG":0.11545,"PCHG":3.97486,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-04-20 02:22:10","ADY":622,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-271","SUBJID":"id-271","SITEID":"CHN-3","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.80752,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-04","TRTSDTM":"2020-08-06 02:22:10","TRTEDTM":"2023-08-06 20:22:10","TRT01SDTM":"2020-08-06 02:22:10","TRT01EDTM":"2022-08-06 14:22:10","TRT02SDTM":"2022-08-06 14:22:10","TRT02EDTM":"2023-08-06 20:22:10","AP01SDTM":"2020-08-06 02:22:10","AP01EDTM":"2022-08-06 14:22:10","AP02SDTM":"2022-08-06 14:22:10","AP02EDTM":"2023-08-06 20:22:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4396,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97925,"AVALU":"g/L","BASE2":2.91665,"BASE":2.90458,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0626,"PCHG2":2.14637,"CHG":0.07467,"PCHG":2.57067,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-12 02:22:10","ADY":797,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-271","SUBJID":"id-271","SITEID":"CHN-3","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.80752,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-04","TRTSDTM":"2020-08-06 02:22:10","TRTEDTM":"2023-08-06 20:22:10","TRT01SDTM":"2020-08-06 02:22:10","TRT01EDTM":"2022-08-06 14:22:10","TRT02SDTM":"2022-08-06 14:22:10","TRT02EDTM":"2023-08-06 20:22:10","AP01SDTM":"2020-08-06 02:22:10","AP01EDTM":"2022-08-06 14:22:10","AP02SDTM":"2022-08-06 14:22:10","AP02EDTM":"2023-08-06 20:22:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3885,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80959,"AVALU":"g/L","BASE2":2.91665,"BASE":2.90458,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10705,"PCHG2":-3.67046,"CHG":-0.09499,"PCHG":-3.27032,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-19 02:22:10","ADY":927,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-271","SUBJID":"id-271","SITEID":"CHN-3","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.80752,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-04","TRTSDTM":"2020-08-06 02:22:10","TRTEDTM":"2023-08-06 20:22:10","TRT01SDTM":"2020-08-06 02:22:10","TRT01EDTM":"2022-08-06 14:22:10","TRT02SDTM":"2022-08-06 14:22:10","TRT02EDTM":"2023-08-06 20:22:10","AP01SDTM":"2020-08-06 02:22:10","AP01EDTM":"2022-08-06 14:22:10","AP02SDTM":"2022-08-06 14:22:10","AP02EDTM":"2023-08-06 20:22:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5769,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87132,"AVALU":"g/L","BASE2":2.91665,"BASE":2.90458,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04533,"PCHG2":-1.55422,"CHG":-0.03327,"PCHG":-1.14529,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-22 02:22:10","ADY":958,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-271","SUBJID":"id-271","SITEID":"CHN-3","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.80752,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-04","TRTSDTM":"2020-08-06 02:22:10","TRTEDTM":"2023-08-06 20:22:10","TRT01SDTM":"2020-08-06 02:22:10","TRT01EDTM":"2022-08-06 14:22:10","TRT02SDTM":"2022-08-06 14:22:10","TRT02EDTM":"2023-08-06 20:22:10","AP01SDTM":"2020-08-06 02:22:10","AP01EDTM":"2022-08-06 14:22:10","AP02SDTM":"2022-08-06 14:22:10","AP02EDTM":"2023-08-06 20:22:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4503,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95908,"AVALU":"g/L","BASE2":2.91665,"BASE":2.90458,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04243,"PCHG2":1.45485,"CHG":0.0545,"PCHG":1.87627,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-12 02:22:10","ADY":979,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-281","SUBJID":"id-281","SITEID":"CHN-3","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.37455,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-31","TRTSDTM":"2020-09-02 16:09:58","TRTEDTM":"2023-09-03 10:09:58","TRT01SDTM":"2020-09-02 16:09:58","TRT01EDTM":"2022-09-03 04:09:58","TRT02SDTM":"2022-09-03 04:09:58","TRT02EDTM":"2023-09-03 10:09:58","AP01SDTM":"2020-09-02 16:09:58","AP01EDTM":"2022-09-03 04:09:58","AP02SDTM":"2022-09-03 04:09:58","AP02EDTM":"2023-09-03 10:09:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-03","EOSDY":1096,"LSTALVDT":"2023-09-16","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":980,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.82966,"AVALU":"U/L","BASE2":18.82966,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-06 16:09:58","ADY":4,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-281","SUBJID":"id-281","SITEID":"CHN-3","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.37455,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-31","TRTSDTM":"2020-09-02 16:09:58","TRTEDTM":"2023-09-03 10:09:58","TRT01SDTM":"2020-09-02 16:09:58","TRT01EDTM":"2022-09-03 04:09:58","TRT02SDTM":"2022-09-03 04:09:58","TRT02EDTM":"2023-09-03 10:09:58","AP01SDTM":"2020-09-02 16:09:58","AP01EDTM":"2022-09-03 04:09:58","AP02SDTM":"2022-09-03 04:09:58","AP02EDTM":"2023-09-03 10:09:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-03","EOSDY":1096,"LSTALVDT":"2023-09-16","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":810,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.91768,"AVALU":"U/L","BASE2":18.82966,"BASE":26.91768,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":8.08802,"PCHG2":42.95362,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-04 16:09:58","ADY":32,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-281","SUBJID":"id-281","SITEID":"CHN-3","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.37455,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-31","TRTSDTM":"2020-09-02 16:09:58","TRTEDTM":"2023-09-03 10:09:58","TRT01SDTM":"2020-09-02 16:09:58","TRT01EDTM":"2022-09-03 04:09:58","TRT02SDTM":"2022-09-03 04:09:58","TRT02EDTM":"2023-09-03 10:09:58","AP01SDTM":"2020-09-02 16:09:58","AP01EDTM":"2022-09-03 04:09:58","AP02SDTM":"2022-09-03 04:09:58","AP02EDTM":"2023-09-03 10:09:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-03","EOSDY":1096,"LSTALVDT":"2023-09-16","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8106,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.59794,"AVALU":"U/L","BASE2":18.82966,"BASE":26.91768,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.76828,"PCHG2":35.94479,"CHG":-1.31974,"PCHG":-4.90287,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-26 16:09:58","ADY":146,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-281","SUBJID":"id-281","SITEID":"CHN-3","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.37455,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-31","TRTSDTM":"2020-09-02 16:09:58","TRTEDTM":"2023-09-03 10:09:58","TRT01SDTM":"2020-09-02 16:09:58","TRT01EDTM":"2022-09-03 04:09:58","TRT02SDTM":"2022-09-03 04:09:58","TRT02EDTM":"2023-09-03 10:09:58","AP01SDTM":"2020-09-02 16:09:58","AP01EDTM":"2022-09-03 04:09:58","AP02SDTM":"2022-09-03 04:09:58","AP02EDTM":"2023-09-03 10:09:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-03","EOSDY":1096,"LSTALVDT":"2023-09-16","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2015,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.98789,"AVALU":"U/L","BASE2":18.82966,"BASE":26.91768,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.15823,"PCHG2":27.39417,"CHG":-2.92979,"PCHG":-10.88426,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-09 16:09:58","ADY":341,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-281","SUBJID":"id-281","SITEID":"CHN-3","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.37455,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-31","TRTSDTM":"2020-09-02 16:09:58","TRTEDTM":"2023-09-03 10:09:58","TRT01SDTM":"2020-09-02 16:09:58","TRT01EDTM":"2022-09-03 04:09:58","TRT02SDTM":"2022-09-03 04:09:58","TRT02EDTM":"2023-09-03 10:09:58","AP01SDTM":"2020-09-02 16:09:58","AP01EDTM":"2022-09-03 04:09:58","AP02SDTM":"2022-09-03 04:09:58","AP02EDTM":"2023-09-03 10:09:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-03","EOSDY":1096,"LSTALVDT":"2023-09-16","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7667,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.68093,"AVALU":"U/L","BASE2":18.82966,"BASE":26.91768,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.85127,"PCHG2":25.76398,"CHG":-3.23675,"PCHG":-12.02463,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-29 16:09:58","ADY":361,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-281","SUBJID":"id-281","SITEID":"CHN-3","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.37455,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-31","TRTSDTM":"2020-09-02 16:09:58","TRTEDTM":"2023-09-03 10:09:58","TRT01SDTM":"2020-09-02 16:09:58","TRT01EDTM":"2022-09-03 04:09:58","TRT02SDTM":"2022-09-03 04:09:58","TRT02EDTM":"2023-09-03 10:09:58","AP01SDTM":"2020-09-02 16:09:58","AP01EDTM":"2022-09-03 04:09:58","AP02SDTM":"2022-09-03 04:09:58","AP02EDTM":"2023-09-03 10:09:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-03","EOSDY":1096,"LSTALVDT":"2023-09-16","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5046,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.89531,"AVALU":"U/L","BASE2":18.82966,"BASE":26.91768,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.06565,"PCHG2":10.97021,"CHG":-6.02237,"PCHG":-22.37328,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-22 16:09:58","ADY":750,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-281","SUBJID":"id-281","SITEID":"CHN-3","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.37455,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-31","TRTSDTM":"2020-09-02 16:09:58","TRTEDTM":"2023-09-03 10:09:58","TRT01SDTM":"2020-09-02 16:09:58","TRT01EDTM":"2022-09-03 04:09:58","TRT02SDTM":"2022-09-03 04:09:58","TRT02EDTM":"2023-09-03 10:09:58","AP01SDTM":"2020-09-02 16:09:58","AP01EDTM":"2022-09-03 04:09:58","AP02SDTM":"2022-09-03 04:09:58","AP02EDTM":"2023-09-03 10:09:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-03","EOSDY":1096,"LSTALVDT":"2023-09-16","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":66,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.32652,"AVALU":"U/L","BASE2":18.82966,"BASE":26.91768,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.49686,"PCHG2":55.74645,"CHG":2.40885,"PCHG":8.94894,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-02 16:09:58","ADY":1095,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-281","SUBJID":"id-281","SITEID":"CHN-3","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.37455,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-31","TRTSDTM":"2020-09-02 16:09:58","TRTEDTM":"2023-09-03 10:09:58","TRT01SDTM":"2020-09-02 16:09:58","TRT01EDTM":"2022-09-03 04:09:58","TRT02SDTM":"2022-09-03 04:09:58","TRT02EDTM":"2023-09-03 10:09:58","AP01SDTM":"2020-09-02 16:09:58","AP01EDTM":"2022-09-03 04:09:58","AP02SDTM":"2022-09-03 04:09:58","AP02EDTM":"2023-09-03 10:09:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-03","EOSDY":1096,"LSTALVDT":"2023-09-16","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2094,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.2176,"AVALU":"mg/L","BASE2":11.2176,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-09-06 16:09:58","ADY":4,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-281","SUBJID":"id-281","SITEID":"CHN-3","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.37455,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-31","TRTSDTM":"2020-09-02 16:09:58","TRTEDTM":"2023-09-03 10:09:58","TRT01SDTM":"2020-09-02 16:09:58","TRT01EDTM":"2022-09-03 04:09:58","TRT02SDTM":"2022-09-03 04:09:58","TRT02EDTM":"2023-09-03 10:09:58","AP01SDTM":"2020-09-02 16:09:58","AP01EDTM":"2022-09-03 04:09:58","AP02SDTM":"2022-09-03 04:09:58","AP02EDTM":"2023-09-03 10:09:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-03","EOSDY":1096,"LSTALVDT":"2023-09-16","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2562,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.28932,"AVALU":"mg/L","BASE2":11.2176,"BASE":8.28932,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.92828,"PCHG2":-26.10436,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-04 16:09:58","ADY":32,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-281","SUBJID":"id-281","SITEID":"CHN-3","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.37455,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-31","TRTSDTM":"2020-09-02 16:09:58","TRTEDTM":"2023-09-03 10:09:58","TRT01SDTM":"2020-09-02 16:09:58","TRT01EDTM":"2022-09-03 04:09:58","TRT02SDTM":"2022-09-03 04:09:58","TRT02EDTM":"2023-09-03 10:09:58","AP01SDTM":"2020-09-02 16:09:58","AP01EDTM":"2022-09-03 04:09:58","AP02SDTM":"2022-09-03 04:09:58","AP02EDTM":"2023-09-03 10:09:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-03","EOSDY":1096,"LSTALVDT":"2023-09-16","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5533,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.6472,"AVALU":"mg/L","BASE2":11.2176,"BASE":8.28932,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.5704,"PCHG2":-22.91396,"CHG":0.35789,"PCHG":4.31744,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-26 16:09:58","ADY":146,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-281","SUBJID":"id-281","SITEID":"CHN-3","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.37455,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-31","TRTSDTM":"2020-09-02 16:09:58","TRTEDTM":"2023-09-03 10:09:58","TRT01SDTM":"2020-09-02 16:09:58","TRT01EDTM":"2022-09-03 04:09:58","TRT02SDTM":"2022-09-03 04:09:58","TRT02EDTM":"2023-09-03 10:09:58","AP01SDTM":"2020-09-02 16:09:58","AP01EDTM":"2022-09-03 04:09:58","AP02SDTM":"2022-09-03 04:09:58","AP02EDTM":"2023-09-03 10:09:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-03","EOSDY":1096,"LSTALVDT":"2023-09-16","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7283,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.52262,"AVALU":"mg/L","BASE2":11.2176,"BASE":8.28932,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.69498,"PCHG2":-15.11004,"CHG":1.2333,"PCHG":14.87817,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-09 16:09:58","ADY":341,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-281","SUBJID":"id-281","SITEID":"CHN-3","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.37455,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-31","TRTSDTM":"2020-09-02 16:09:58","TRTEDTM":"2023-09-03 10:09:58","TRT01SDTM":"2020-09-02 16:09:58","TRT01EDTM":"2022-09-03 04:09:58","TRT02SDTM":"2022-09-03 04:09:58","TRT02EDTM":"2023-09-03 10:09:58","AP01SDTM":"2020-09-02 16:09:58","AP01EDTM":"2022-09-03 04:09:58","AP02SDTM":"2022-09-03 04:09:58","AP02EDTM":"2023-09-03 10:09:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-03","EOSDY":1096,"LSTALVDT":"2023-09-16","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7823,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.61649,"AVALU":"mg/L","BASE2":11.2176,"BASE":8.28932,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.60111,"PCHG2":-23.18777,"CHG":0.32717,"PCHG":3.94689,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-29 16:09:58","ADY":361,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-281","SUBJID":"id-281","SITEID":"CHN-3","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.37455,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-31","TRTSDTM":"2020-09-02 16:09:58","TRTEDTM":"2023-09-03 10:09:58","TRT01SDTM":"2020-09-02 16:09:58","TRT01EDTM":"2022-09-03 04:09:58","TRT02SDTM":"2022-09-03 04:09:58","TRT02EDTM":"2023-09-03 10:09:58","AP01SDTM":"2020-09-02 16:09:58","AP01EDTM":"2022-09-03 04:09:58","AP02SDTM":"2022-09-03 04:09:58","AP02EDTM":"2023-09-03 10:09:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-03","EOSDY":1096,"LSTALVDT":"2023-09-16","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7521,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.81313,"AVALU":"mg/L","BASE2":11.2176,"BASE":8.28932,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.40447,"PCHG2":-30.34936,"CHG":-0.47619,"PCHG":-5.7446,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-09-22 16:09:58","ADY":750,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-281","SUBJID":"id-281","SITEID":"CHN-3","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.37455,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-31","TRTSDTM":"2020-09-02 16:09:58","TRTEDTM":"2023-09-03 10:09:58","TRT01SDTM":"2020-09-02 16:09:58","TRT01EDTM":"2022-09-03 04:09:58","TRT02SDTM":"2022-09-03 04:09:58","TRT02EDTM":"2023-09-03 10:09:58","AP01SDTM":"2020-09-02 16:09:58","AP01EDTM":"2022-09-03 04:09:58","AP02SDTM":"2022-09-03 04:09:58","AP02EDTM":"2023-09-03 10:09:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-03","EOSDY":1096,"LSTALVDT":"2023-09-16","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2832,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.34784,"AVALU":"mg/L","BASE2":11.2176,"BASE":8.28932,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.86976,"PCHG2":-16.66809,"CHG":1.05852,"PCHG":12.76972,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-02 16:09:58","ADY":1095,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-281","SUBJID":"id-281","SITEID":"CHN-3","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.37455,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-31","TRTSDTM":"2020-09-02 16:09:58","TRTEDTM":"2023-09-03 10:09:58","TRT01SDTM":"2020-09-02 16:09:58","TRT01EDTM":"2022-09-03 04:09:58","TRT02SDTM":"2022-09-03 04:09:58","TRT02EDTM":"2023-09-03 10:09:58","AP01SDTM":"2020-09-02 16:09:58","AP01EDTM":"2022-09-03 04:09:58","AP02SDTM":"2022-09-03 04:09:58","AP02EDTM":"2023-09-03 10:09:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-03","EOSDY":1096,"LSTALVDT":"2023-09-16","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6817,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86668,"AVALU":"g/L","BASE2":2.86668,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-06 16:09:58","ADY":4,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-281","SUBJID":"id-281","SITEID":"CHN-3","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.37455,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-31","TRTSDTM":"2020-09-02 16:09:58","TRTEDTM":"2023-09-03 10:09:58","TRT01SDTM":"2020-09-02 16:09:58","TRT01EDTM":"2022-09-03 04:09:58","TRT02SDTM":"2022-09-03 04:09:58","TRT02EDTM":"2023-09-03 10:09:58","AP01SDTM":"2020-09-02 16:09:58","AP01EDTM":"2022-09-03 04:09:58","AP02SDTM":"2022-09-03 04:09:58","AP02EDTM":"2023-09-03 10:09:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-03","EOSDY":1096,"LSTALVDT":"2023-09-16","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1269,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78006,"AVALU":"g/L","BASE2":2.86668,"BASE":2.78006,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.08662,"PCHG2":-3.02168,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-04 16:09:58","ADY":32,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-281","SUBJID":"id-281","SITEID":"CHN-3","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.37455,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-31","TRTSDTM":"2020-09-02 16:09:58","TRTEDTM":"2023-09-03 10:09:58","TRT01SDTM":"2020-09-02 16:09:58","TRT01EDTM":"2022-09-03 04:09:58","TRT02SDTM":"2022-09-03 04:09:58","TRT02EDTM":"2023-09-03 10:09:58","AP01SDTM":"2020-09-02 16:09:58","AP01EDTM":"2022-09-03 04:09:58","AP02SDTM":"2022-09-03 04:09:58","AP02EDTM":"2023-09-03 10:09:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-03","EOSDY":1096,"LSTALVDT":"2023-09-16","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5162,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90166,"AVALU":"g/L","BASE2":2.86668,"BASE":2.78006,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03498,"PCHG2":1.22039,"CHG":0.12161,"PCHG":4.37424,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-26 16:09:58","ADY":146,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-281","SUBJID":"id-281","SITEID":"CHN-3","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.37455,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-31","TRTSDTM":"2020-09-02 16:09:58","TRTEDTM":"2023-09-03 10:09:58","TRT01SDTM":"2020-09-02 16:09:58","TRT01EDTM":"2022-09-03 04:09:58","TRT02SDTM":"2022-09-03 04:09:58","TRT02EDTM":"2023-09-03 10:09:58","AP01SDTM":"2020-09-02 16:09:58","AP01EDTM":"2022-09-03 04:09:58","AP02SDTM":"2022-09-03 04:09:58","AP02EDTM":"2023-09-03 10:09:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-03","EOSDY":1096,"LSTALVDT":"2023-09-16","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":884,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88122,"AVALU":"g/L","BASE2":2.86668,"BASE":2.78006,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01454,"PCHG2":0.50737,"CHG":0.10117,"PCHG":3.639,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-09 16:09:58","ADY":341,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-281","SUBJID":"id-281","SITEID":"CHN-3","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.37455,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-31","TRTSDTM":"2020-09-02 16:09:58","TRTEDTM":"2023-09-03 10:09:58","TRT01SDTM":"2020-09-02 16:09:58","TRT01EDTM":"2022-09-03 04:09:58","TRT02SDTM":"2022-09-03 04:09:58","TRT02EDTM":"2023-09-03 10:09:58","AP01SDTM":"2020-09-02 16:09:58","AP01EDTM":"2022-09-03 04:09:58","AP02SDTM":"2022-09-03 04:09:58","AP02EDTM":"2023-09-03 10:09:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-03","EOSDY":1096,"LSTALVDT":"2023-09-16","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1773,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05692,"AVALU":"g/L","BASE2":2.86668,"BASE":2.78006,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.19024,"PCHG2":6.63608,"CHG":0.27686,"PCHG":9.95868,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-08-29 16:09:58","ADY":361,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-281","SUBJID":"id-281","SITEID":"CHN-3","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.37455,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-31","TRTSDTM":"2020-09-02 16:09:58","TRTEDTM":"2023-09-03 10:09:58","TRT01SDTM":"2020-09-02 16:09:58","TRT01EDTM":"2022-09-03 04:09:58","TRT02SDTM":"2022-09-03 04:09:58","TRT02EDTM":"2023-09-03 10:09:58","AP01SDTM":"2020-09-02 16:09:58","AP01EDTM":"2022-09-03 04:09:58","AP02SDTM":"2022-09-03 04:09:58","AP02EDTM":"2023-09-03 10:09:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-03","EOSDY":1096,"LSTALVDT":"2023-09-16","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2092,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.10935,"AVALU":"g/L","BASE2":2.86668,"BASE":2.78006,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.24267,"PCHG2":8.46504,"CHG":0.32929,"PCHG":11.84463,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-09-22 16:09:58","ADY":750,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-281","SUBJID":"id-281","SITEID":"CHN-3","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.37455,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-31","TRTSDTM":"2020-09-02 16:09:58","TRTEDTM":"2023-09-03 10:09:58","TRT01SDTM":"2020-09-02 16:09:58","TRT01EDTM":"2022-09-03 04:09:58","TRT02SDTM":"2022-09-03 04:09:58","TRT02EDTM":"2023-09-03 10:09:58","AP01SDTM":"2020-09-02 16:09:58","AP01EDTM":"2022-09-03 04:09:58","AP02SDTM":"2022-09-03 04:09:58","AP02EDTM":"2023-09-03 10:09:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-03","EOSDY":1096,"LSTALVDT":"2023-09-16","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3313,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95991,"AVALU":"g/L","BASE2":2.86668,"BASE":2.78006,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09323,"PCHG2":3.25214,"CHG":0.17985,"PCHG":6.4693,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-02 16:09:58","ADY":1095,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-303","SUBJID":"id-303","SITEID":"CHN-3","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.81708,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-05 01:05:40","TRT01SDTM":"2020-01-05 01:05:40","AP01SDTM":"2020-01-05 01:05:40","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6309,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.07538,"AVALU":"U/L","BASE2":20.07538,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-21 01:05:40","ADY":472,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-303","SUBJID":"id-303","SITEID":"CHN-3","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.81708,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-05 01:05:40","TRT01SDTM":"2020-01-05 01:05:40","AP01SDTM":"2020-01-05 01:05:40","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4228,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.05993,"AVALU":"U/L","BASE2":20.07538,"BASE":14.05993,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-6.01545,"PCHG2":-29.96432,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-08 01:05:40","ADY":489,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-303","SUBJID":"id-303","SITEID":"CHN-3","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.81708,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-05 01:05:40","TRT01SDTM":"2020-01-05 01:05:40","AP01SDTM":"2020-01-05 01:05:40","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8239,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.97906,"AVALU":"U/L","BASE2":20.07538,"BASE":14.05993,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.09632,"PCHG2":-30.36716,"CHG":-0.08087,"PCHG":-0.57519,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-19 01:05:40","ADY":500,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-303","SUBJID":"id-303","SITEID":"CHN-3","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.81708,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-05 01:05:40","TRT01SDTM":"2020-01-05 01:05:40","AP01SDTM":"2020-01-05 01:05:40","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3203,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.34951,"AVALU":"U/L","BASE2":20.07538,"BASE":14.05993,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.72587,"PCHG2":-58.40921,"CHG":-5.71042,"PCHG":-40.61486,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-25 01:05:40","ADY":567,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-303","SUBJID":"id-303","SITEID":"CHN-3","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.81708,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-05 01:05:40","TRT01SDTM":"2020-01-05 01:05:40","AP01SDTM":"2020-01-05 01:05:40","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4571,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.54651,"AVALU":"U/L","BASE2":20.07538,"BASE":14.05993,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.52888,"PCHG2":-42.48425,"CHG":-2.51342,"PCHG":-17.8765,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-30 01:05:40","ADY":634,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-303","SUBJID":"id-303","SITEID":"CHN-3","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.81708,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-05 01:05:40","TRT01SDTM":"2020-01-05 01:05:40","AP01SDTM":"2020-01-05 01:05:40","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5256,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.72053,"AVALU":"U/L","BASE2":20.07538,"BASE":14.05993,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.35485,"PCHG2":-16.71129,"CHG":2.6606,"PCHG":18.92326,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-05 01:05:40","ADY":670,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-303","SUBJID":"id-303","SITEID":"CHN-3","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.81708,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-05 01:05:40","TRT01SDTM":"2020-01-05 01:05:40","AP01SDTM":"2020-01-05 01:05:40","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":297,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.85311,"AVALU":"U/L","BASE2":20.07538,"BASE":14.05993,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.22228,"PCHG2":-21.03211,"CHG":1.79318,"PCHG":12.7538,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-01 01:05:40","ADY":727,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-303","SUBJID":"id-303","SITEID":"CHN-3","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.81708,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-05 01:05:40","TRT01SDTM":"2020-01-05 01:05:40","AP01SDTM":"2020-01-05 01:05:40","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":182,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.35519,"AVALU":"mg/L","BASE2":10.35519,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"","ATOXGR":"3","BTOXGR":"-3","ADTM":"2021-04-21 01:05:40","ADY":472,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-303","SUBJID":"id-303","SITEID":"CHN-3","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.81708,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-05 01:05:40","TRT01SDTM":"2020-01-05 01:05:40","AP01SDTM":"2020-01-05 01:05:40","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5439,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.96106,"AVALU":"mg/L","BASE2":10.35519,"BASE":7.96106,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.39413,"PCHG2":-23.12009,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2021-05-08 01:05:40","ADY":489,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-303","SUBJID":"id-303","SITEID":"CHN-3","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.81708,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-05 01:05:40","TRT01SDTM":"2020-01-05 01:05:40","AP01SDTM":"2020-01-05 01:05:40","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6990,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.79055,"AVALU":"mg/L","BASE2":10.35519,"BASE":7.96106,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.56464,"PCHG2":-24.76671,"CHG":-0.17051,"PCHG":-2.1418,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-3","ADTM":"2021-05-19 01:05:40","ADY":500,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-303","SUBJID":"id-303","SITEID":"CHN-3","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.81708,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-05 01:05:40","TRT01SDTM":"2020-01-05 01:05:40","AP01SDTM":"2020-01-05 01:05:40","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5186,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.18561,"AVALU":"mg/L","BASE2":10.35519,"BASE":7.96106,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.16958,"PCHG2":-20.95158,"CHG":0.22455,"PCHG":2.82066,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-07-25 01:05:40","ADY":567,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-303","SUBJID":"id-303","SITEID":"CHN-3","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.81708,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-05 01:05:40","TRT01SDTM":"2020-01-05 01:05:40","AP01SDTM":"2020-01-05 01:05:40","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5195,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.02475,"AVALU":"mg/L","BASE2":10.35519,"BASE":7.96106,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.33044,"PCHG2":-12.84802,"CHG":1.06369,"PCHG":13.3612,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-09-30 01:05:40","ADY":634,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-303","SUBJID":"id-303","SITEID":"CHN-3","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.81708,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-05 01:05:40","TRT01SDTM":"2020-01-05 01:05:40","AP01SDTM":"2020-01-05 01:05:40","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4345,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.90275,"AVALU":"mg/L","BASE2":10.35519,"BASE":7.96106,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.45244,"PCHG2":-14.02618,"CHG":0.94169,"PCHG":11.82872,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-11-05 01:05:40","ADY":670,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-303","SUBJID":"id-303","SITEID":"CHN-3","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.81708,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-05 01:05:40","TRT01SDTM":"2020-01-05 01:05:40","AP01SDTM":"2020-01-05 01:05:40","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":697,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.48061,"AVALU":"mg/L","BASE2":10.35519,"BASE":7.96106,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.87458,"PCHG2":-18.10281,"CHG":0.51955,"PCHG":6.52614,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2022-01-01 01:05:40","ADY":727,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-303","SUBJID":"id-303","SITEID":"CHN-3","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.81708,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-05 01:05:40","TRT01SDTM":"2020-01-05 01:05:40","AP01SDTM":"2020-01-05 01:05:40","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6480,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92122,"AVALU":"g/L","BASE2":2.92122,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-21 01:05:40","ADY":472,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-303","SUBJID":"id-303","SITEID":"CHN-3","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.81708,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-05 01:05:40","TRT01SDTM":"2020-01-05 01:05:40","AP01SDTM":"2020-01-05 01:05:40","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7050,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92907,"AVALU":"g/L","BASE2":2.92122,"BASE":2.92907,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.00785,"PCHG2":0.26878,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-08 01:05:40","ADY":489,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-303","SUBJID":"id-303","SITEID":"CHN-3","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.81708,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-05 01:05:40","TRT01SDTM":"2020-01-05 01:05:40","AP01SDTM":"2020-01-05 01:05:40","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2639,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83079,"AVALU":"g/L","BASE2":2.92122,"BASE":2.92907,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09044,"PCHG2":-3.09586,"CHG":-0.09829,"PCHG":-3.35562,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-19 01:05:40","ADY":500,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-303","SUBJID":"id-303","SITEID":"CHN-3","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.81708,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-05 01:05:40","TRT01SDTM":"2020-01-05 01:05:40","AP01SDTM":"2020-01-05 01:05:40","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4088,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95033,"AVALU":"g/L","BASE2":2.92122,"BASE":2.92907,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02911,"PCHG2":0.99637,"CHG":0.02125,"PCHG":0.72565,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-25 01:05:40","ADY":567,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-303","SUBJID":"id-303","SITEID":"CHN-3","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.81708,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-05 01:05:40","TRT01SDTM":"2020-01-05 01:05:40","AP01SDTM":"2020-01-05 01:05:40","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3113,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.12217,"AVALU":"g/L","BASE2":2.92122,"BASE":2.92907,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.20095,"PCHG2":6.87883,"CHG":0.19309,"PCHG":6.59234,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-09-30 01:05:40","ADY":634,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-303","SUBJID":"id-303","SITEID":"CHN-3","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.81708,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-05 01:05:40","TRT01SDTM":"2020-01-05 01:05:40","AP01SDTM":"2020-01-05 01:05:40","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5717,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.73836,"AVALU":"g/L","BASE2":2.92122,"BASE":2.92907,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18287,"PCHG2":-6.2599,"CHG":-0.19072,"PCHG":-6.51118,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-05 01:05:40","ADY":670,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-303","SUBJID":"id-303","SITEID":"CHN-3","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.81708,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-05 01:05:40","TRT01SDTM":"2020-01-05 01:05:40","AP01SDTM":"2020-01-05 01:05:40","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2263,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.11587,"AVALU":"g/L","BASE2":2.92122,"BASE":2.92907,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.19465,"PCHG2":6.66336,"CHG":0.1868,"PCHG":6.37745,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-01-01 01:05:40","ADY":727,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-333","SUBJID":"id-333","SITEID":"CHN-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.72886,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-13","TRTSDTM":"2020-01-13 07:01:27","TRT01SDTM":"2020-01-13 07:01:27","AP01SDTM":"2020-01-13 07:01:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3878,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.8764,"AVALU":"U/L","BASE2":25.8764,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-26 07:01:27","ADY":13,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-333","SUBJID":"id-333","SITEID":"CHN-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.72886,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-13","TRTSDTM":"2020-01-13 07:01:27","TRT01SDTM":"2020-01-13 07:01:27","AP01SDTM":"2020-01-13 07:01:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4857,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.14363,"AVALU":"U/L","BASE2":25.8764,"BASE":29.14363,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":3.26723,"PCHG2":12.6263,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-24 07:01:27","ADY":285,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-333","SUBJID":"id-333","SITEID":"CHN-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.72886,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-13","TRTSDTM":"2020-01-13 07:01:27","TRT01SDTM":"2020-01-13 07:01:27","AP01SDTM":"2020-01-13 07:01:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7659,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.67408,"AVALU":"U/L","BASE2":25.8764,"BASE":29.14363,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-15.20231,"PCHG2":-58.74974,"CHG":-18.46955,"PCHG":-63.37422,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-01 07:01:27","ADY":354,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-333","SUBJID":"id-333","SITEID":"CHN-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.72886,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-13","TRTSDTM":"2020-01-13 07:01:27","TRT01SDTM":"2020-01-13 07:01:27","AP01SDTM":"2020-01-13 07:01:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7030,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.23369,"AVALU":"U/L","BASE2":25.8764,"BASE":29.14363,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.64271,"PCHG2":-14.07733,"CHG":-6.90994,"PCHG":-23.70994,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-01 07:01:27","ADY":505,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-333","SUBJID":"id-333","SITEID":"CHN-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.72886,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-13","TRTSDTM":"2020-01-13 07:01:27","TRT01SDTM":"2020-01-13 07:01:27","AP01SDTM":"2020-01-13 07:01:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5967,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.42049,"AVALU":"U/L","BASE2":25.8764,"BASE":29.14363,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.45591,"PCHG2":-13.35545,"CHG":-6.72314,"PCHG":-23.06899,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-20 07:01:27","ADY":554,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-333","SUBJID":"id-333","SITEID":"CHN-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.72886,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-13","TRTSDTM":"2020-01-13 07:01:27","TRT01SDTM":"2020-01-13 07:01:27","AP01SDTM":"2020-01-13 07:01:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4530,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.75778,"AVALU":"U/L","BASE2":25.8764,"BASE":29.14363,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.88138,"PCHG2":11.13518,"CHG":-0.38585,"PCHG":-1.32395,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-25 07:01:27","ADY":559,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-333","SUBJID":"id-333","SITEID":"CHN-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.72886,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-13","TRTSDTM":"2020-01-13 07:01:27","TRT01SDTM":"2020-01-13 07:01:27","AP01SDTM":"2020-01-13 07:01:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1460,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.77796,"AVALU":"U/L","BASE2":25.8764,"BASE":29.14363,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.09844,"PCHG2":-8.10947,"CHG":-5.36567,"PCHG":-18.41112,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-20 07:01:27","ADY":646,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-333","SUBJID":"id-333","SITEID":"CHN-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.72886,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-13","TRTSDTM":"2020-01-13 07:01:27","TRT01SDTM":"2020-01-13 07:01:27","AP01SDTM":"2020-01-13 07:01:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4690,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.51211,"AVALU":"mg/L","BASE2":9.51211,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-01-26 07:01:27","ADY":13,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-333","SUBJID":"id-333","SITEID":"CHN-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.72886,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-13","TRTSDTM":"2020-01-13 07:01:27","TRT01SDTM":"2020-01-13 07:01:27","AP01SDTM":"2020-01-13 07:01:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4158,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.08604,"AVALU":"mg/L","BASE2":9.51211,"BASE":10.08604,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.57392,"PCHG2":6.03362,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-10-24 07:01:27","ADY":285,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-333","SUBJID":"id-333","SITEID":"CHN-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.72886,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-13","TRTSDTM":"2020-01-13 07:01:27","TRT01SDTM":"2020-01-13 07:01:27","AP01SDTM":"2020-01-13 07:01:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5029,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.99785,"AVALU":"mg/L","BASE2":9.51211,"BASE":10.08604,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.51426,"PCHG2":-5.40635,"CHG":-1.08818,"PCHG":-10.789,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-01-01 07:01:27","ADY":354,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-333","SUBJID":"id-333","SITEID":"CHN-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.72886,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-13","TRTSDTM":"2020-01-13 07:01:27","TRT01SDTM":"2020-01-13 07:01:27","AP01SDTM":"2020-01-13 07:01:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2326,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.54996,"AVALU":"mg/L","BASE2":9.51211,"BASE":10.08604,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.03785,"PCHG2":10.91079,"CHG":0.46392,"PCHG":4.59964,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"3","BTOXGR":"1","ADTM":"2021-06-01 07:01:27","ADY":505,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-333","SUBJID":"id-333","SITEID":"CHN-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.72886,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-13","TRTSDTM":"2020-01-13 07:01:27","TRT01SDTM":"2020-01-13 07:01:27","AP01SDTM":"2020-01-13 07:01:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5538,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":5.80507,"AVALU":"mg/L","BASE2":9.51211,"BASE":10.08604,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.70705,"PCHG2":-38.97186,"CHG":-4.28097,"PCHG":-42.44454,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-2","BTOXGR":"1","ADTM":"2021-07-20 07:01:27","ADY":554,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-333","SUBJID":"id-333","SITEID":"CHN-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.72886,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-13","TRTSDTM":"2020-01-13 07:01:27","TRT01SDTM":"2020-01-13 07:01:27","AP01SDTM":"2020-01-13 07:01:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4839,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.72833,"AVALU":"mg/L","BASE2":9.51211,"BASE":10.08604,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.78378,"PCHG2":-8.23985,"CHG":-1.35771,"PCHG":-13.46127,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-07-25 07:01:27","ADY":559,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-333","SUBJID":"id-333","SITEID":"CHN-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.72886,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-13","TRTSDTM":"2020-01-13 07:01:27","TRT01SDTM":"2020-01-13 07:01:27","AP01SDTM":"2020-01-13 07:01:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":905,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.05022,"AVALU":"mg/L","BASE2":9.51211,"BASE":10.08604,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.53811,"PCHG2":5.65709,"CHG":-0.03582,"PCHG":-0.35511,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"1","ADTM":"2021-10-20 07:01:27","ADY":646,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-333","SUBJID":"id-333","SITEID":"CHN-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.72886,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-13","TRTSDTM":"2020-01-13 07:01:27","TRT01SDTM":"2020-01-13 07:01:27","AP01SDTM":"2020-01-13 07:01:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":656,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77032,"AVALU":"g/L","BASE2":2.77032,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"4","ADTM":"2020-01-26 07:01:27","ADY":13,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-333","SUBJID":"id-333","SITEID":"CHN-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.72886,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-13","TRTSDTM":"2020-01-13 07:01:27","TRT01SDTM":"2020-01-13 07:01:27","AP01SDTM":"2020-01-13 07:01:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2756,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.09833,"AVALU":"g/L","BASE2":2.77032,"BASE":3.09833,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.32801,"PCHG2":11.84018,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"4","BTOXGR":"4","ADTM":"2020-10-24 07:01:27","ADY":285,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-333","SUBJID":"id-333","SITEID":"CHN-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.72886,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-13","TRTSDTM":"2020-01-13 07:01:27","TRT01SDTM":"2020-01-13 07:01:27","AP01SDTM":"2020-01-13 07:01:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1971,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94937,"AVALU":"g/L","BASE2":2.77032,"BASE":3.09833,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17905,"PCHG2":6.46312,"CHG":-0.14896,"PCHG":-4.80781,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2021-01-01 07:01:27","ADY":354,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-333","SUBJID":"id-333","SITEID":"CHN-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.72886,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-13","TRTSDTM":"2020-01-13 07:01:27","TRT01SDTM":"2020-01-13 07:01:27","AP01SDTM":"2020-01-13 07:01:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7334,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86823,"AVALU":"g/L","BASE2":2.77032,"BASE":3.09833,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09792,"PCHG2":3.53443,"CHG":-0.2301,"PCHG":-7.42644,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2021-06-01 07:01:27","ADY":505,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-333","SUBJID":"id-333","SITEID":"CHN-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.72886,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-13","TRTSDTM":"2020-01-13 07:01:27","TRT01SDTM":"2020-01-13 07:01:27","AP01SDTM":"2020-01-13 07:01:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5833,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81492,"AVALU":"g/L","BASE2":2.77032,"BASE":3.09833,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0446,"PCHG2":1.61005,"CHG":-0.28341,"PCHG":-9.1471,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2021-07-20 07:01:27","ADY":554,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-333","SUBJID":"id-333","SITEID":"CHN-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.72886,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-13","TRTSDTM":"2020-01-13 07:01:27","TRT01SDTM":"2020-01-13 07:01:27","AP01SDTM":"2020-01-13 07:01:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6147,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85637,"AVALU":"g/L","BASE2":2.77032,"BASE":3.09833,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08606,"PCHG2":3.10641,"CHG":-0.24195,"PCHG":-7.80915,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2021-07-25 07:01:27","ADY":559,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-333","SUBJID":"id-333","SITEID":"CHN-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.72886,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-13","TRTSDTM":"2020-01-13 07:01:27","TRT01SDTM":"2020-01-13 07:01:27","AP01SDTM":"2020-01-13 07:01:27","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1299,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79884,"AVALU":"g/L","BASE2":2.77032,"BASE":3.09833,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02853,"PCHG2":1.02976,"CHG":-0.29948,"PCHG":-9.66596,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2021-10-20 07:01:27","ADY":646,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-361","SUBJID":"id-361","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.32503,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-11","TRTSDTM":"2019-04-11 18:40:28","TRTEDTM":"2022-04-11 12:40:28","TRT01SDTM":"2019-04-11 18:40:28","TRT01EDTM":"2021-04-11 06:40:28","TRT02SDTM":"2021-04-11 06:40:28","TRT02EDTM":"2022-04-11 12:40:28","AP01SDTM":"2019-04-11 18:40:28","AP01EDTM":"2021-04-11 06:40:28","AP02SDTM":"2021-04-11 06:40:28","AP02EDTM":"2022-04-11 12:40:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-11","EOSDY":1096,"LSTALVDT":"2022-04-26","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1803,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.43871,"AVALU":"U/L","BASE2":17.43871,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-04-17 18:40:28","ADY":6,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-361","SUBJID":"id-361","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.32503,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-11","TRTSDTM":"2019-04-11 18:40:28","TRTEDTM":"2022-04-11 12:40:28","TRT01SDTM":"2019-04-11 18:40:28","TRT01EDTM":"2021-04-11 06:40:28","TRT02SDTM":"2021-04-11 06:40:28","TRT02EDTM":"2022-04-11 12:40:28","AP01SDTM":"2019-04-11 18:40:28","AP01EDTM":"2021-04-11 06:40:28","AP02SDTM":"2021-04-11 06:40:28","AP02EDTM":"2022-04-11 12:40:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-11","EOSDY":1096,"LSTALVDT":"2022-04-26","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2760,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.89735,"AVALU":"U/L","BASE2":17.43871,"BASE":21.89735,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":4.45863,"PCHG2":25.56744,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-16 18:40:28","ADY":371,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-361","SUBJID":"id-361","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.32503,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-11","TRTSDTM":"2019-04-11 18:40:28","TRTEDTM":"2022-04-11 12:40:28","TRT01SDTM":"2019-04-11 18:40:28","TRT01EDTM":"2021-04-11 06:40:28","TRT02SDTM":"2021-04-11 06:40:28","TRT02EDTM":"2022-04-11 12:40:28","AP01SDTM":"2019-04-11 18:40:28","AP01EDTM":"2021-04-11 06:40:28","AP02SDTM":"2021-04-11 06:40:28","AP02EDTM":"2022-04-11 12:40:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-11","EOSDY":1096,"LSTALVDT":"2022-04-26","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1045,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.10456,"AVALU":"U/L","BASE2":17.43871,"BASE":21.89735,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.33415,"PCHG2":-99.40039,"CHG":-21.79278,"PCHG":-99.52248,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-06-28 18:40:28","ADY":444,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-361","SUBJID":"id-361","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.32503,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-11","TRTSDTM":"2019-04-11 18:40:28","TRTEDTM":"2022-04-11 12:40:28","TRT01SDTM":"2019-04-11 18:40:28","TRT01EDTM":"2021-04-11 06:40:28","TRT02SDTM":"2021-04-11 06:40:28","TRT02EDTM":"2022-04-11 12:40:28","AP01SDTM":"2019-04-11 18:40:28","AP01EDTM":"2021-04-11 06:40:28","AP02SDTM":"2021-04-11 06:40:28","AP02EDTM":"2022-04-11 12:40:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-11","EOSDY":1096,"LSTALVDT":"2022-04-26","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6540,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.46993,"AVALU":"U/L","BASE2":17.43871,"BASE":21.89735,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.96878,"PCHG2":-11.28971,"CHG":-6.42741,"PCHG":-29.35247,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-19 18:40:28","ADY":618,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-361","SUBJID":"id-361","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.32503,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-11","TRTSDTM":"2019-04-11 18:40:28","TRTEDTM":"2022-04-11 12:40:28","TRT01SDTM":"2019-04-11 18:40:28","TRT01EDTM":"2021-04-11 06:40:28","TRT02SDTM":"2021-04-11 06:40:28","TRT02EDTM":"2022-04-11 12:40:28","AP01SDTM":"2019-04-11 18:40:28","AP01EDTM":"2021-04-11 06:40:28","AP02SDTM":"2021-04-11 06:40:28","AP02EDTM":"2022-04-11 12:40:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-11","EOSDY":1096,"LSTALVDT":"2022-04-26","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4016,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.042,"AVALU":"U/L","BASE2":17.43871,"BASE":21.89735,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.39672,"PCHG2":-30.94676,"CHG":-9.85535,"PCHG":-45.00705,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-25 18:40:28","ADY":624,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-361","SUBJID":"id-361","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.32503,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-11","TRTSDTM":"2019-04-11 18:40:28","TRTEDTM":"2022-04-11 12:40:28","TRT01SDTM":"2019-04-11 18:40:28","TRT01EDTM":"2021-04-11 06:40:28","TRT02SDTM":"2021-04-11 06:40:28","TRT02EDTM":"2022-04-11 12:40:28","AP01SDTM":"2019-04-11 18:40:28","AP01EDTM":"2021-04-11 06:40:28","AP02SDTM":"2021-04-11 06:40:28","AP02EDTM":"2022-04-11 12:40:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-11","EOSDY":1096,"LSTALVDT":"2022-04-26","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3298,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.58104,"AVALU":"U/L","BASE2":17.43871,"BASE":21.89735,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.85767,"PCHG2":-79.46497,"CHG":-18.3163,"PCHG":-83.64622,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-06-22 18:40:28","ADY":803,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-361","SUBJID":"id-361","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.32503,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-11","TRTSDTM":"2019-04-11 18:40:28","TRTEDTM":"2022-04-11 12:40:28","TRT01SDTM":"2019-04-11 18:40:28","TRT01EDTM":"2021-04-11 06:40:28","TRT02SDTM":"2021-04-11 06:40:28","TRT02EDTM":"2022-04-11 12:40:28","AP01SDTM":"2019-04-11 18:40:28","AP01EDTM":"2021-04-11 06:40:28","AP02SDTM":"2021-04-11 06:40:28","AP02EDTM":"2022-04-11 12:40:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-11","EOSDY":1096,"LSTALVDT":"2022-04-26","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":403,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.26607,"AVALU":"U/L","BASE2":17.43871,"BASE":21.89735,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.17264,"PCHG2":-23.92746,"CHG":-8.63127,"PCHG":-39.41698,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-24 18:40:28","ADY":897,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-361","SUBJID":"id-361","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.32503,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-11","TRTSDTM":"2019-04-11 18:40:28","TRTEDTM":"2022-04-11 12:40:28","TRT01SDTM":"2019-04-11 18:40:28","TRT01EDTM":"2021-04-11 06:40:28","TRT02SDTM":"2021-04-11 06:40:28","TRT02EDTM":"2022-04-11 12:40:28","AP01SDTM":"2019-04-11 18:40:28","AP01EDTM":"2021-04-11 06:40:28","AP02SDTM":"2021-04-11 06:40:28","AP02EDTM":"2022-04-11 12:40:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-11","EOSDY":1096,"LSTALVDT":"2022-04-26","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6831,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.59735,"AVALU":"mg/L","BASE2":8.59735,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-04-17 18:40:28","ADY":6,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-361","SUBJID":"id-361","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.32503,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-11","TRTSDTM":"2019-04-11 18:40:28","TRTEDTM":"2022-04-11 12:40:28","TRT01SDTM":"2019-04-11 18:40:28","TRT01EDTM":"2021-04-11 06:40:28","TRT02SDTM":"2021-04-11 06:40:28","TRT02EDTM":"2022-04-11 12:40:28","AP01SDTM":"2019-04-11 18:40:28","AP01EDTM":"2021-04-11 06:40:28","AP02SDTM":"2021-04-11 06:40:28","AP02EDTM":"2022-04-11 12:40:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-11","EOSDY":1096,"LSTALVDT":"2022-04-26","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7763,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.68294,"AVALU":"mg/L","BASE2":8.59735,"BASE":8.68294,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.0856,"PCHG2":0.99562,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-16 18:40:28","ADY":371,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-361","SUBJID":"id-361","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.32503,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-11","TRTSDTM":"2019-04-11 18:40:28","TRTEDTM":"2022-04-11 12:40:28","TRT01SDTM":"2019-04-11 18:40:28","TRT01EDTM":"2021-04-11 06:40:28","TRT02SDTM":"2021-04-11 06:40:28","TRT02EDTM":"2022-04-11 12:40:28","AP01SDTM":"2019-04-11 18:40:28","AP01EDTM":"2021-04-11 06:40:28","AP02SDTM":"2021-04-11 06:40:28","AP02EDTM":"2022-04-11 12:40:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-11","EOSDY":1096,"LSTALVDT":"2022-04-26","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3704,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.46769,"AVALU":"mg/L","BASE2":8.59735,"BASE":8.68294,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.87034,"PCHG2":10.12338,"CHG":0.78475,"PCHG":9.03779,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-28 18:40:28","ADY":444,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-361","SUBJID":"id-361","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.32503,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-11","TRTSDTM":"2019-04-11 18:40:28","TRTEDTM":"2022-04-11 12:40:28","TRT01SDTM":"2019-04-11 18:40:28","TRT01EDTM":"2021-04-11 06:40:28","TRT02SDTM":"2021-04-11 06:40:28","TRT02EDTM":"2022-04-11 12:40:28","AP01SDTM":"2019-04-11 18:40:28","AP01EDTM":"2021-04-11 06:40:28","AP02SDTM":"2021-04-11 06:40:28","AP02EDTM":"2022-04-11 12:40:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-11","EOSDY":1096,"LSTALVDT":"2022-04-26","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6876,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.43662,"AVALU":"mg/L","BASE2":8.59735,"BASE":8.68294,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.83927,"PCHG2":21.39347,"CHG":1.75367,"PCHG":20.19677,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-12-19 18:40:28","ADY":618,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-361","SUBJID":"id-361","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.32503,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-11","TRTSDTM":"2019-04-11 18:40:28","TRTEDTM":"2022-04-11 12:40:28","TRT01SDTM":"2019-04-11 18:40:28","TRT01EDTM":"2021-04-11 06:40:28","TRT02SDTM":"2021-04-11 06:40:28","TRT02EDTM":"2022-04-11 12:40:28","AP01SDTM":"2019-04-11 18:40:28","AP01EDTM":"2021-04-11 06:40:28","AP02SDTM":"2021-04-11 06:40:28","AP02EDTM":"2022-04-11 12:40:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-11","EOSDY":1096,"LSTALVDT":"2022-04-26","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5304,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.38104,"AVALU":"mg/L","BASE2":8.59735,"BASE":8.68294,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.21631,"PCHG2":-14.1475,"CHG":-1.30191,"PCHG":-14.99384,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-12-25 18:40:28","ADY":624,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-361","SUBJID":"id-361","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.32503,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-11","TRTSDTM":"2019-04-11 18:40:28","TRTEDTM":"2022-04-11 12:40:28","TRT01SDTM":"2019-04-11 18:40:28","TRT01EDTM":"2021-04-11 06:40:28","TRT02SDTM":"2021-04-11 06:40:28","TRT02EDTM":"2022-04-11 12:40:28","AP01SDTM":"2019-04-11 18:40:28","AP01EDTM":"2021-04-11 06:40:28","AP02SDTM":"2021-04-11 06:40:28","AP02EDTM":"2022-04-11 12:40:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-11","EOSDY":1096,"LSTALVDT":"2022-04-26","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2474,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.60003,"AVALU":"mg/L","BASE2":8.59735,"BASE":8.68294,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.99731,"PCHG2":-11.60025,"CHG":-1.08291,"PCHG":-12.47169,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-06-22 18:40:28","ADY":803,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-361","SUBJID":"id-361","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.32503,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-11","TRTSDTM":"2019-04-11 18:40:28","TRTEDTM":"2022-04-11 12:40:28","TRT01SDTM":"2019-04-11 18:40:28","TRT01EDTM":"2021-04-11 06:40:28","TRT02SDTM":"2021-04-11 06:40:28","TRT02EDTM":"2022-04-11 12:40:28","AP01SDTM":"2019-04-11 18:40:28","AP01EDTM":"2021-04-11 06:40:28","AP02SDTM":"2021-04-11 06:40:28","AP02EDTM":"2022-04-11 12:40:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-11","EOSDY":1096,"LSTALVDT":"2022-04-26","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":602,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.4242,"AVALU":"mg/L","BASE2":8.59735,"BASE":8.68294,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.82685,"PCHG2":9.6175,"CHG":0.74125,"PCHG":8.53689,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-24 18:40:28","ADY":897,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-361","SUBJID":"id-361","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.32503,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-11","TRTSDTM":"2019-04-11 18:40:28","TRTEDTM":"2022-04-11 12:40:28","TRT01SDTM":"2019-04-11 18:40:28","TRT01EDTM":"2021-04-11 06:40:28","TRT02SDTM":"2021-04-11 06:40:28","TRT02EDTM":"2022-04-11 12:40:28","AP01SDTM":"2019-04-11 18:40:28","AP01EDTM":"2021-04-11 06:40:28","AP02SDTM":"2021-04-11 06:40:28","AP02EDTM":"2022-04-11 12:40:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-11","EOSDY":1096,"LSTALVDT":"2022-04-26","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6881,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.09391,"AVALU":"g/L","BASE2":3.09391,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"4","BTOXGR":"0","ADTM":"2019-04-17 18:40:28","ADY":6,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-361","SUBJID":"id-361","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.32503,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-11","TRTSDTM":"2019-04-11 18:40:28","TRTEDTM":"2022-04-11 12:40:28","TRT01SDTM":"2019-04-11 18:40:28","TRT01EDTM":"2021-04-11 06:40:28","TRT02SDTM":"2021-04-11 06:40:28","TRT02EDTM":"2022-04-11 12:40:28","AP01SDTM":"2019-04-11 18:40:28","AP01EDTM":"2021-04-11 06:40:28","AP02SDTM":"2021-04-11 06:40:28","AP02EDTM":"2022-04-11 12:40:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-11","EOSDY":1096,"LSTALVDT":"2022-04-26","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8320,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87716,"AVALU":"g/L","BASE2":3.09391,"BASE":2.87716,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.21674,"PCHG2":-7.00548,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-16 18:40:28","ADY":371,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-361","SUBJID":"id-361","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.32503,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-11","TRTSDTM":"2019-04-11 18:40:28","TRTEDTM":"2022-04-11 12:40:28","TRT01SDTM":"2019-04-11 18:40:28","TRT01EDTM":"2021-04-11 06:40:28","TRT02SDTM":"2021-04-11 06:40:28","TRT02EDTM":"2022-04-11 12:40:28","AP01SDTM":"2019-04-11 18:40:28","AP01EDTM":"2021-04-11 06:40:28","AP02SDTM":"2021-04-11 06:40:28","AP02EDTM":"2022-04-11 12:40:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-11","EOSDY":1096,"LSTALVDT":"2022-04-26","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8277,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93706,"AVALU":"g/L","BASE2":3.09391,"BASE":2.87716,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15685,"PCHG2":-5.06957,"CHG":0.0599,"PCHG":2.08175,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-28 18:40:28","ADY":444,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-361","SUBJID":"id-361","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.32503,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-11","TRTSDTM":"2019-04-11 18:40:28","TRTEDTM":"2022-04-11 12:40:28","TRT01SDTM":"2019-04-11 18:40:28","TRT01EDTM":"2021-04-11 06:40:28","TRT02SDTM":"2021-04-11 06:40:28","TRT02EDTM":"2022-04-11 12:40:28","AP01SDTM":"2019-04-11 18:40:28","AP01EDTM":"2021-04-11 06:40:28","AP02SDTM":"2021-04-11 06:40:28","AP02EDTM":"2022-04-11 12:40:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-11","EOSDY":1096,"LSTALVDT":"2022-04-26","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1561,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.1437,"AVALU":"g/L","BASE2":3.09391,"BASE":2.87716,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0498,"PCHG2":1.6095,"CHG":0.26654,"PCHG":9.26397,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-12-19 18:40:28","ADY":618,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-361","SUBJID":"id-361","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.32503,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-11","TRTSDTM":"2019-04-11 18:40:28","TRTEDTM":"2022-04-11 12:40:28","TRT01SDTM":"2019-04-11 18:40:28","TRT01EDTM":"2021-04-11 06:40:28","TRT02SDTM":"2021-04-11 06:40:28","TRT02EDTM":"2022-04-11 12:40:28","AP01SDTM":"2019-04-11 18:40:28","AP01EDTM":"2021-04-11 06:40:28","AP02SDTM":"2021-04-11 06:40:28","AP02EDTM":"2022-04-11 12:40:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-11","EOSDY":1096,"LSTALVDT":"2022-04-26","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2031,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83629,"AVALU":"g/L","BASE2":3.09391,"BASE":2.87716,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.25762,"PCHG2":-8.32658,"CHG":-0.04087,"PCHG":-1.42062,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-25 18:40:28","ADY":624,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-361","SUBJID":"id-361","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.32503,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-11","TRTSDTM":"2019-04-11 18:40:28","TRTEDTM":"2022-04-11 12:40:28","TRT01SDTM":"2019-04-11 18:40:28","TRT01EDTM":"2021-04-11 06:40:28","TRT02SDTM":"2021-04-11 06:40:28","TRT02EDTM":"2022-04-11 12:40:28","AP01SDTM":"2019-04-11 18:40:28","AP01EDTM":"2021-04-11 06:40:28","AP02SDTM":"2021-04-11 06:40:28","AP02EDTM":"2022-04-11 12:40:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-11","EOSDY":1096,"LSTALVDT":"2022-04-26","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7433,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94171,"AVALU":"g/L","BASE2":3.09391,"BASE":2.87716,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1522,"PCHG2":-4.91939,"CHG":0.06454,"PCHG":2.24324,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-22 18:40:28","ADY":803,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-361","SUBJID":"id-361","SITEID":"CHN-3","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.32503,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-11","TRTSDTM":"2019-04-11 18:40:28","TRTEDTM":"2022-04-11 12:40:28","TRT01SDTM":"2019-04-11 18:40:28","TRT01EDTM":"2021-04-11 06:40:28","TRT02SDTM":"2021-04-11 06:40:28","TRT02EDTM":"2022-04-11 12:40:28","AP01SDTM":"2019-04-11 18:40:28","AP01EDTM":"2021-04-11 06:40:28","AP02SDTM":"2021-04-11 06:40:28","AP02EDTM":"2022-04-11 12:40:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-11","EOSDY":1096,"LSTALVDT":"2022-04-26","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3790,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94685,"AVALU":"g/L","BASE2":3.09391,"BASE":2.87716,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14706,"PCHG2":-4.75323,"CHG":0.06968,"PCHG":2.42192,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-24 18:40:28","ADY":897,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-81","SUBJID":"id-81","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.81724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 23:01:01","TRTEDTM":"2023-09-10 17:01:01","TRT01SDTM":"2020-09-09 23:01:01","TRT01EDTM":"2022-09-10 11:01:01","TRT02SDTM":"2022-09-10 11:01:01","TRT02EDTM":"2023-09-10 17:01:01","AP01SDTM":"2020-09-09 23:01:01","AP01EDTM":"2022-09-10 11:01:01","AP02SDTM":"2022-09-10 11:01:01","AP02EDTM":"2023-09-10 17:01:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-10-05","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6196,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.99078,"AVALU":"U/L","BASE2":18.99078,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-18 23:01:01","ADY":708,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-81","SUBJID":"id-81","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.81724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 23:01:01","TRTEDTM":"2023-09-10 17:01:01","TRT01SDTM":"2020-09-09 23:01:01","TRT01EDTM":"2022-09-10 11:01:01","TRT02SDTM":"2022-09-10 11:01:01","TRT02EDTM":"2023-09-10 17:01:01","AP01SDTM":"2020-09-09 23:01:01","AP01EDTM":"2022-09-10 11:01:01","AP02SDTM":"2022-09-10 11:01:01","AP02EDTM":"2023-09-10 17:01:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-10-05","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4948,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.37295,"AVALU":"U/L","BASE2":18.99078,"BASE":15.37295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-3.61784,"PCHG2":-19.05048,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-15 23:01:01","ADY":766,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-81","SUBJID":"id-81","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.81724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 23:01:01","TRTEDTM":"2023-09-10 17:01:01","TRT01SDTM":"2020-09-09 23:01:01","TRT01EDTM":"2022-09-10 11:01:01","TRT02SDTM":"2022-09-10 11:01:01","TRT02EDTM":"2023-09-10 17:01:01","AP01SDTM":"2020-09-09 23:01:01","AP01EDTM":"2022-09-10 11:01:01","AP02SDTM":"2022-09-10 11:01:01","AP02EDTM":"2023-09-10 17:01:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-10-05","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2046,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.96338,"AVALU":"U/L","BASE2":18.99078,"BASE":15.37295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.02741,"PCHG2":-68.59858,"CHG":-9.40957,"PCHG":-61.20864,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-11-19 23:01:01","ADY":801,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-81","SUBJID":"id-81","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.81724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 23:01:01","TRTEDTM":"2023-09-10 17:01:01","TRT01SDTM":"2020-09-09 23:01:01","TRT01EDTM":"2022-09-10 11:01:01","TRT02SDTM":"2022-09-10 11:01:01","TRT02EDTM":"2023-09-10 17:01:01","AP01SDTM":"2020-09-09 23:01:01","AP01EDTM":"2022-09-10 11:01:01","AP02SDTM":"2022-09-10 11:01:01","AP02EDTM":"2023-09-10 17:01:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-10-05","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6547,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.73897,"AVALU":"U/L","BASE2":18.99078,"BASE":15.37295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.25181,"PCHG2":-48.71738,"CHG":-5.63398,"PCHG":-36.64864,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-08 23:01:01","ADY":851,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-81","SUBJID":"id-81","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.81724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 23:01:01","TRTEDTM":"2023-09-10 17:01:01","TRT01SDTM":"2020-09-09 23:01:01","TRT01EDTM":"2022-09-10 11:01:01","TRT02SDTM":"2022-09-10 11:01:01","TRT02EDTM":"2023-09-10 17:01:01","AP01SDTM":"2020-09-09 23:01:01","AP01EDTM":"2022-09-10 11:01:01","AP02SDTM":"2022-09-10 11:01:01","AP02EDTM":"2023-09-10 17:01:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-10-05","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":34,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.33867,"AVALU":"U/L","BASE2":18.99078,"BASE":15.37295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.65211,"PCHG2":-24.49668,"CHG":-1.03428,"PCHG":-6.7279,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-24 23:01:01","ADY":867,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-81","SUBJID":"id-81","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.81724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 23:01:01","TRTEDTM":"2023-09-10 17:01:01","TRT01SDTM":"2020-09-09 23:01:01","TRT01EDTM":"2022-09-10 11:01:01","TRT02SDTM":"2022-09-10 11:01:01","TRT02EDTM":"2023-09-10 17:01:01","AP01SDTM":"2020-09-09 23:01:01","AP01EDTM":"2022-09-10 11:01:01","AP02SDTM":"2022-09-10 11:01:01","AP02EDTM":"2023-09-10 17:01:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-10-05","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5037,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.27226,"AVALU":"U/L","BASE2":18.99078,"BASE":15.37295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.71853,"PCHG2":-88.03496,"CHG":-13.10069,"PCHG":-85.21913,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2023-05-09 23:01:01","ADY":972,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-81","SUBJID":"id-81","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.81724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 23:01:01","TRTEDTM":"2023-09-10 17:01:01","TRT01SDTM":"2020-09-09 23:01:01","TRT01EDTM":"2022-09-10 11:01:01","TRT02SDTM":"2022-09-10 11:01:01","TRT02EDTM":"2023-09-10 17:01:01","AP01SDTM":"2020-09-09 23:01:01","AP01EDTM":"2022-09-10 11:01:01","AP02SDTM":"2022-09-10 11:01:01","AP02EDTM":"2023-09-10 17:01:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-10-05","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1020,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.74048,"AVALU":"U/L","BASE2":18.99078,"BASE":15.37295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.74969,"PCHG2":35.54193,"CHG":10.36753,"PCHG":67.44008,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-29 23:01:01","ADY":1053,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-81","SUBJID":"id-81","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.81724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 23:01:01","TRTEDTM":"2023-09-10 17:01:01","TRT01SDTM":"2020-09-09 23:01:01","TRT01EDTM":"2022-09-10 11:01:01","TRT02SDTM":"2022-09-10 11:01:01","TRT02EDTM":"2023-09-10 17:01:01","AP01SDTM":"2020-09-09 23:01:01","AP01EDTM":"2022-09-10 11:01:01","AP02SDTM":"2022-09-10 11:01:01","AP02EDTM":"2023-09-10 17:01:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-10-05","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2775,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.94329,"AVALU":"mg/L","BASE2":8.94329,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-18 23:01:01","ADY":708,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-81","SUBJID":"id-81","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.81724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 23:01:01","TRTEDTM":"2023-09-10 17:01:01","TRT01SDTM":"2020-09-09 23:01:01","TRT01EDTM":"2022-09-10 11:01:01","TRT02SDTM":"2022-09-10 11:01:01","TRT02EDTM":"2023-09-10 17:01:01","AP01SDTM":"2020-09-09 23:01:01","AP01EDTM":"2022-09-10 11:01:01","AP02SDTM":"2022-09-10 11:01:01","AP02EDTM":"2023-09-10 17:01:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-10-05","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3850,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.85293,"AVALU":"mg/L","BASE2":8.94329,"BASE":9.85293,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.90964,"PCHG2":10.17119,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-15 23:01:01","ADY":766,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-81","SUBJID":"id-81","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.81724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 23:01:01","TRTEDTM":"2023-09-10 17:01:01","TRT01SDTM":"2020-09-09 23:01:01","TRT01EDTM":"2022-09-10 11:01:01","TRT02SDTM":"2022-09-10 11:01:01","TRT02EDTM":"2023-09-10 17:01:01","AP01SDTM":"2020-09-09 23:01:01","AP01EDTM":"2022-09-10 11:01:01","AP02SDTM":"2022-09-10 11:01:01","AP02EDTM":"2023-09-10 17:01:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-10-05","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6969,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.45746,"AVALU":"mg/L","BASE2":8.94329,"BASE":9.85293,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.48583,"PCHG2":-16.61391,"CHG":-2.39547,"PCHG":-24.31225,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-11-19 23:01:01","ADY":801,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-81","SUBJID":"id-81","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.81724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 23:01:01","TRTEDTM":"2023-09-10 17:01:01","TRT01SDTM":"2020-09-09 23:01:01","TRT01EDTM":"2022-09-10 11:01:01","TRT02SDTM":"2022-09-10 11:01:01","TRT02EDTM":"2023-09-10 17:01:01","AP01SDTM":"2020-09-09 23:01:01","AP01EDTM":"2022-09-10 11:01:01","AP02SDTM":"2022-09-10 11:01:01","AP02EDTM":"2023-09-10 17:01:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-10-05","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4625,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.81045,"AVALU":"mg/L","BASE2":8.94329,"BASE":9.85293,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.13284,"PCHG2":-12.6669,"CHG":-2.04248,"PCHG":-20.72964,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2023-01-08 23:01:01","ADY":851,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-81","SUBJID":"id-81","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.81724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 23:01:01","TRTEDTM":"2023-09-10 17:01:01","TRT01SDTM":"2020-09-09 23:01:01","TRT01EDTM":"2022-09-10 11:01:01","TRT02SDTM":"2022-09-10 11:01:01","TRT02EDTM":"2023-09-10 17:01:01","AP01SDTM":"2020-09-09 23:01:01","AP01EDTM":"2022-09-10 11:01:01","AP02SDTM":"2022-09-10 11:01:01","AP02EDTM":"2023-09-10 17:01:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-10-05","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3359,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.12151,"AVALU":"mg/L","BASE2":8.94329,"BASE":9.85293,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.17822,"PCHG2":13.17431,"CHG":0.26858,"PCHG":2.72587,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2023-01-24 23:01:01","ADY":867,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-81","SUBJID":"id-81","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.81724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 23:01:01","TRTEDTM":"2023-09-10 17:01:01","TRT01SDTM":"2020-09-09 23:01:01","TRT01EDTM":"2022-09-10 11:01:01","TRT02SDTM":"2022-09-10 11:01:01","TRT02EDTM":"2023-09-10 17:01:01","AP01SDTM":"2020-09-09 23:01:01","AP01EDTM":"2022-09-10 11:01:01","AP02SDTM":"2022-09-10 11:01:01","AP02EDTM":"2023-09-10 17:01:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-10-05","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4531,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.41479,"AVALU":"mg/L","BASE2":8.94329,"BASE":9.85293,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.47149,"PCHG2":16.45361,"CHG":0.56186,"PCHG":5.70242,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2023-05-09 23:01:01","ADY":972,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-81","SUBJID":"id-81","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.81724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 23:01:01","TRTEDTM":"2023-09-10 17:01:01","TRT01SDTM":"2020-09-09 23:01:01","TRT01EDTM":"2022-09-10 11:01:01","TRT02SDTM":"2022-09-10 11:01:01","TRT02EDTM":"2023-09-10 17:01:01","AP01SDTM":"2020-09-09 23:01:01","AP01EDTM":"2022-09-10 11:01:01","AP02SDTM":"2022-09-10 11:01:01","AP02EDTM":"2023-09-10 17:01:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-10-05","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6450,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.4514,"AVALU":"mg/L","BASE2":8.94329,"BASE":9.85293,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.50811,"PCHG2":5.68143,"CHG":-0.40153,"PCHG":-4.07526,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-29 23:01:01","ADY":1053,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-81","SUBJID":"id-81","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.81724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 23:01:01","TRTEDTM":"2023-09-10 17:01:01","TRT01SDTM":"2020-09-09 23:01:01","TRT01EDTM":"2022-09-10 11:01:01","TRT02SDTM":"2022-09-10 11:01:01","TRT02EDTM":"2023-09-10 17:01:01","AP01SDTM":"2020-09-09 23:01:01","AP01EDTM":"2022-09-10 11:01:01","AP02SDTM":"2022-09-10 11:01:01","AP02EDTM":"2023-09-10 17:01:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-10-05","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6271,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86753,"AVALU":"g/L","BASE2":2.86753,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-18 23:01:01","ADY":708,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-81","SUBJID":"id-81","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.81724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 23:01:01","TRTEDTM":"2023-09-10 17:01:01","TRT01SDTM":"2020-09-09 23:01:01","TRT01EDTM":"2022-09-10 11:01:01","TRT02SDTM":"2022-09-10 11:01:01","TRT02EDTM":"2023-09-10 17:01:01","AP01SDTM":"2020-09-09 23:01:01","AP01EDTM":"2022-09-10 11:01:01","AP02SDTM":"2022-09-10 11:01:01","AP02EDTM":"2023-09-10 17:01:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-10-05","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4657,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86841,"AVALU":"g/L","BASE2":2.86753,"BASE":2.86841,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.00088,"PCHG2":0.03073,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-15 23:01:01","ADY":766,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-81","SUBJID":"id-81","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.81724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 23:01:01","TRTEDTM":"2023-09-10 17:01:01","TRT01SDTM":"2020-09-09 23:01:01","TRT01EDTM":"2022-09-10 11:01:01","TRT02SDTM":"2022-09-10 11:01:01","TRT02EDTM":"2023-09-10 17:01:01","AP01SDTM":"2020-09-09 23:01:01","AP01EDTM":"2022-09-10 11:01:01","AP02SDTM":"2022-09-10 11:01:01","AP02EDTM":"2023-09-10 17:01:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-10-05","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3369,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90924,"AVALU":"g/L","BASE2":2.86753,"BASE":2.86841,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04171,"PCHG2":1.45443,"CHG":0.04083,"PCHG":1.42326,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-19 23:01:01","ADY":801,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-81","SUBJID":"id-81","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.81724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 23:01:01","TRTEDTM":"2023-09-10 17:01:01","TRT01SDTM":"2020-09-09 23:01:01","TRT01EDTM":"2022-09-10 11:01:01","TRT02SDTM":"2022-09-10 11:01:01","TRT02EDTM":"2023-09-10 17:01:01","AP01SDTM":"2020-09-09 23:01:01","AP01EDTM":"2022-09-10 11:01:01","AP02SDTM":"2022-09-10 11:01:01","AP02EDTM":"2023-09-10 17:01:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-10-05","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":320,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92056,"AVALU":"g/L","BASE2":2.86753,"BASE":2.86841,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05303,"PCHG2":1.84919,"CHG":0.05214,"PCHG":1.8179,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-08 23:01:01","ADY":851,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-81","SUBJID":"id-81","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.81724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 23:01:01","TRTEDTM":"2023-09-10 17:01:01","TRT01SDTM":"2020-09-09 23:01:01","TRT01EDTM":"2022-09-10 11:01:01","TRT02SDTM":"2022-09-10 11:01:01","TRT02EDTM":"2023-09-10 17:01:01","AP01SDTM":"2020-09-09 23:01:01","AP01EDTM":"2022-09-10 11:01:01","AP02SDTM":"2022-09-10 11:01:01","AP02EDTM":"2023-09-10 17:01:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-10-05","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7821,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7942,"AVALU":"g/L","BASE2":2.86753,"BASE":2.86841,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07334,"PCHG2":-2.55753,"CHG":-0.07422,"PCHG":-2.58746,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-24 23:01:01","ADY":867,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-81","SUBJID":"id-81","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.81724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 23:01:01","TRTEDTM":"2023-09-10 17:01:01","TRT01SDTM":"2020-09-09 23:01:01","TRT01EDTM":"2022-09-10 11:01:01","TRT02SDTM":"2022-09-10 11:01:01","TRT02EDTM":"2023-09-10 17:01:01","AP01SDTM":"2020-09-09 23:01:01","AP01EDTM":"2022-09-10 11:01:01","AP02SDTM":"2022-09-10 11:01:01","AP02EDTM":"2023-09-10 17:01:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-10-05","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3960,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85679,"AVALU":"g/L","BASE2":2.86753,"BASE":2.86841,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01075,"PCHG2":-0.37473,"CHG":-0.01163,"PCHG":-0.40534,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-09 23:01:01","ADY":972,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-3-id-81","SUBJID":"id-81","SITEID":"CHN-3","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-3","INVNAM":"Dr. CHN-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.81724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 23:01:01","TRTEDTM":"2023-09-10 17:01:01","TRT01SDTM":"2020-09-09 23:01:01","TRT01EDTM":"2022-09-10 11:01:01","TRT02SDTM":"2022-09-10 11:01:01","TRT02EDTM":"2023-09-10 17:01:01","AP01SDTM":"2020-09-09 23:01:01","AP01EDTM":"2022-09-10 11:01:01","AP02SDTM":"2022-09-10 11:01:01","AP02EDTM":"2023-09-10 17:01:01","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-10-05","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1999,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00833,"AVALU":"g/L","BASE2":2.86753,"BASE":2.86841,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14079,"PCHG2":4.90993,"CHG":0.13991,"PCHG":4.8777,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2023-07-29 23:01:01","ADY":1053,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-114","SUBJID":"id-114","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.10419,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-16","TRTSDTM":"2019-08-18 22:39:14","TRTEDTM":"2022-08-18 16:39:14","TRT01SDTM":"2019-08-18 22:39:14","TRT01EDTM":"2021-08-18 10:39:14","TRT02SDTM":"2021-08-18 10:39:14","TRT02EDTM":"2022-08-18 16:39:14","AP01SDTM":"2019-08-18 22:39:14","AP01EDTM":"2021-08-18 10:39:14","AP02SDTM":"2021-08-18 10:39:14","AP02EDTM":"2022-08-18 16:39:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-18","EOSDY":1096,"LSTALVDT":"2022-09-07","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5424,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.93946,"AVALU":"U/L","BASE2":23.93946,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-11 22:39:14","ADY":24,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-114","SUBJID":"id-114","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.10419,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-16","TRTSDTM":"2019-08-18 22:39:14","TRTEDTM":"2022-08-18 16:39:14","TRT01SDTM":"2019-08-18 22:39:14","TRT01EDTM":"2021-08-18 10:39:14","TRT02SDTM":"2021-08-18 10:39:14","TRT02EDTM":"2022-08-18 16:39:14","AP01SDTM":"2019-08-18 22:39:14","AP01EDTM":"2021-08-18 10:39:14","AP02SDTM":"2021-08-18 10:39:14","AP02EDTM":"2022-08-18 16:39:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-18","EOSDY":1096,"LSTALVDT":"2022-09-07","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2994,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.69794,"AVALU":"U/L","BASE2":23.93946,"BASE":19.69794,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-4.24152,"PCHG2":-17.71769,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-02 22:39:14","ADY":137,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-114","SUBJID":"id-114","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.10419,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-16","TRTSDTM":"2019-08-18 22:39:14","TRTEDTM":"2022-08-18 16:39:14","TRT01SDTM":"2019-08-18 22:39:14","TRT01EDTM":"2021-08-18 10:39:14","TRT02SDTM":"2021-08-18 10:39:14","TRT02EDTM":"2022-08-18 16:39:14","AP01SDTM":"2019-08-18 22:39:14","AP01EDTM":"2021-08-18 10:39:14","AP02SDTM":"2021-08-18 10:39:14","AP02EDTM":"2022-08-18 16:39:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-18","EOSDY":1096,"LSTALVDT":"2022-09-07","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8164,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.14577,"AVALU":"U/L","BASE2":23.93946,"BASE":19.69794,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.20631,"PCHG2":9.2162,"CHG":6.44783,"PCHG":32.7335,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-18 22:39:14","ADY":184,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-114","SUBJID":"id-114","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.10419,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-16","TRTSDTM":"2019-08-18 22:39:14","TRTEDTM":"2022-08-18 16:39:14","TRT01SDTM":"2019-08-18 22:39:14","TRT01EDTM":"2021-08-18 10:39:14","TRT02SDTM":"2021-08-18 10:39:14","TRT02EDTM":"2022-08-18 16:39:14","AP01SDTM":"2019-08-18 22:39:14","AP01EDTM":"2021-08-18 10:39:14","AP02SDTM":"2021-08-18 10:39:14","AP02EDTM":"2022-08-18 16:39:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-18","EOSDY":1096,"LSTALVDT":"2022-09-07","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2894,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.85979,"AVALU":"U/L","BASE2":23.93946,"BASE":19.69794,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.07968,"PCHG2":-46.28206,"CHG":-6.83816,"PCHG":-34.71508,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-08 22:39:14","ADY":203,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-114","SUBJID":"id-114","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.10419,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-16","TRTSDTM":"2019-08-18 22:39:14","TRTEDTM":"2022-08-18 16:39:14","TRT01SDTM":"2019-08-18 22:39:14","TRT01EDTM":"2021-08-18 10:39:14","TRT02SDTM":"2021-08-18 10:39:14","TRT02EDTM":"2022-08-18 16:39:14","AP01SDTM":"2019-08-18 22:39:14","AP01EDTM":"2021-08-18 10:39:14","AP02SDTM":"2021-08-18 10:39:14","AP02EDTM":"2022-08-18 16:39:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-18","EOSDY":1096,"LSTALVDT":"2022-09-07","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2565,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.5704,"AVALU":"U/L","BASE2":23.93946,"BASE":19.69794,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.36906,"PCHG2":-39.13648,"CHG":-5.12754,"PCHG":-26.03086,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-21 22:39:14","ADY":216,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-114","SUBJID":"id-114","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.10419,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-16","TRTSDTM":"2019-08-18 22:39:14","TRTEDTM":"2022-08-18 16:39:14","TRT01SDTM":"2019-08-18 22:39:14","TRT01EDTM":"2021-08-18 10:39:14","TRT02SDTM":"2021-08-18 10:39:14","TRT02EDTM":"2022-08-18 16:39:14","AP01SDTM":"2019-08-18 22:39:14","AP01EDTM":"2021-08-18 10:39:14","AP02SDTM":"2021-08-18 10:39:14","AP02EDTM":"2022-08-18 16:39:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-18","EOSDY":1096,"LSTALVDT":"2022-09-07","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1973,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.41932,"AVALU":"U/L","BASE2":23.93946,"BASE":19.69794,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.47986,"PCHG2":14.53606,"CHG":7.72137,"PCHG":39.19888,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-28 22:39:14","ADY":710,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-114","SUBJID":"id-114","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.10419,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-16","TRTSDTM":"2019-08-18 22:39:14","TRTEDTM":"2022-08-18 16:39:14","TRT01SDTM":"2019-08-18 22:39:14","TRT01EDTM":"2021-08-18 10:39:14","TRT02SDTM":"2021-08-18 10:39:14","TRT02EDTM":"2022-08-18 16:39:14","AP01SDTM":"2019-08-18 22:39:14","AP01EDTM":"2021-08-18 10:39:14","AP02SDTM":"2021-08-18 10:39:14","AP02EDTM":"2022-08-18 16:39:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-18","EOSDY":1096,"LSTALVDT":"2022-09-07","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1814,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.88673,"AVALU":"U/L","BASE2":23.93946,"BASE":19.69794,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-23.05274,"PCHG2":-96.29597,"CHG":-18.81122,"PCHG":-95.49839,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-05-20 22:39:14","ADY":1006,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-114","SUBJID":"id-114","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.10419,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-16","TRTSDTM":"2019-08-18 22:39:14","TRTEDTM":"2022-08-18 16:39:14","TRT01SDTM":"2019-08-18 22:39:14","TRT01EDTM":"2021-08-18 10:39:14","TRT02SDTM":"2021-08-18 10:39:14","TRT02EDTM":"2022-08-18 16:39:14","AP01SDTM":"2019-08-18 22:39:14","AP01EDTM":"2021-08-18 10:39:14","AP02SDTM":"2021-08-18 10:39:14","AP02EDTM":"2022-08-18 16:39:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-18","EOSDY":1096,"LSTALVDT":"2022-09-07","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":458,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.0472,"AVALU":"mg/L","BASE2":9.0472,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2019-09-11 22:39:14","ADY":24,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-114","SUBJID":"id-114","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.10419,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-16","TRTSDTM":"2019-08-18 22:39:14","TRTEDTM":"2022-08-18 16:39:14","TRT01SDTM":"2019-08-18 22:39:14","TRT01EDTM":"2021-08-18 10:39:14","TRT02SDTM":"2021-08-18 10:39:14","TRT02EDTM":"2022-08-18 16:39:14","AP01SDTM":"2019-08-18 22:39:14","AP01EDTM":"2021-08-18 10:39:14","AP02SDTM":"2021-08-18 10:39:14","AP02EDTM":"2022-08-18 16:39:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-18","EOSDY":1096,"LSTALVDT":"2022-09-07","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6954,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.46737,"AVALU":"mg/L","BASE2":9.0472,"BASE":7.46737,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.57983,"PCHG2":-17.46209,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2020-01-02 22:39:14","ADY":137,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-114","SUBJID":"id-114","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.10419,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-16","TRTSDTM":"2019-08-18 22:39:14","TRTEDTM":"2022-08-18 16:39:14","TRT01SDTM":"2019-08-18 22:39:14","TRT01EDTM":"2021-08-18 10:39:14","TRT02SDTM":"2021-08-18 10:39:14","TRT02EDTM":"2022-08-18 16:39:14","AP01SDTM":"2019-08-18 22:39:14","AP01EDTM":"2021-08-18 10:39:14","AP02SDTM":"2021-08-18 10:39:14","AP02EDTM":"2022-08-18 16:39:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-18","EOSDY":1096,"LSTALVDT":"2022-09-07","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3210,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.49563,"AVALU":"mg/L","BASE2":9.0472,"BASE":7.46737,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.55156,"PCHG2":-6.09652,"CHG":1.02827,"PCHG":13.77012,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-02-18 22:39:14","ADY":184,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-114","SUBJID":"id-114","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.10419,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-16","TRTSDTM":"2019-08-18 22:39:14","TRTEDTM":"2022-08-18 16:39:14","TRT01SDTM":"2019-08-18 22:39:14","TRT01EDTM":"2021-08-18 10:39:14","TRT02SDTM":"2021-08-18 10:39:14","TRT02EDTM":"2022-08-18 16:39:14","AP01SDTM":"2019-08-18 22:39:14","AP01EDTM":"2021-08-18 10:39:14","AP02SDTM":"2021-08-18 10:39:14","AP02EDTM":"2022-08-18 16:39:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-18","EOSDY":1096,"LSTALVDT":"2022-09-07","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1712,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.73752,"AVALU":"mg/L","BASE2":9.0472,"BASE":7.46737,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.30968,"PCHG2":-3.42295,"CHG":1.27015,"PCHG":17.00933,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-03-08 22:39:14","ADY":203,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-114","SUBJID":"id-114","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.10419,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-16","TRTSDTM":"2019-08-18 22:39:14","TRTEDTM":"2022-08-18 16:39:14","TRT01SDTM":"2019-08-18 22:39:14","TRT01EDTM":"2021-08-18 10:39:14","TRT02SDTM":"2021-08-18 10:39:14","TRT02EDTM":"2022-08-18 16:39:14","AP01SDTM":"2019-08-18 22:39:14","AP01EDTM":"2021-08-18 10:39:14","AP02SDTM":"2021-08-18 10:39:14","AP02EDTM":"2022-08-18 16:39:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-18","EOSDY":1096,"LSTALVDT":"2022-09-07","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3893,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.59963,"AVALU":"mg/L","BASE2":9.0472,"BASE":7.46737,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.44757,"PCHG2":-4.94707,"CHG":1.13226,"PCHG":15.16276,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-03-21 22:39:14","ADY":216,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-114","SUBJID":"id-114","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.10419,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-16","TRTSDTM":"2019-08-18 22:39:14","TRTEDTM":"2022-08-18 16:39:14","TRT01SDTM":"2019-08-18 22:39:14","TRT01EDTM":"2021-08-18 10:39:14","TRT02SDTM":"2021-08-18 10:39:14","TRT02EDTM":"2022-08-18 16:39:14","AP01SDTM":"2019-08-18 22:39:14","AP01EDTM":"2021-08-18 10:39:14","AP02SDTM":"2021-08-18 10:39:14","AP02EDTM":"2022-08-18 16:39:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-18","EOSDY":1096,"LSTALVDT":"2022-09-07","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1255,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.70867,"AVALU":"mg/L","BASE2":9.0472,"BASE":7.46737,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.33852,"PCHG2":-3.74173,"CHG":1.24131,"PCHG":16.6231,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-07-28 22:39:14","ADY":710,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-114","SUBJID":"id-114","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.10419,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-16","TRTSDTM":"2019-08-18 22:39:14","TRTEDTM":"2022-08-18 16:39:14","TRT01SDTM":"2019-08-18 22:39:14","TRT01EDTM":"2021-08-18 10:39:14","TRT02SDTM":"2021-08-18 10:39:14","TRT02EDTM":"2022-08-18 16:39:14","AP01SDTM":"2019-08-18 22:39:14","AP01EDTM":"2021-08-18 10:39:14","AP02SDTM":"2021-08-18 10:39:14","AP02EDTM":"2022-08-18 16:39:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-18","EOSDY":1096,"LSTALVDT":"2022-09-07","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6599,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.67664,"AVALU":"mg/L","BASE2":9.0472,"BASE":7.46737,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.37055,"PCHG2":-4.09578,"CHG":1.20928,"PCHG":16.19416,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-05-20 22:39:14","ADY":1006,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-114","SUBJID":"id-114","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.10419,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-16","TRTSDTM":"2019-08-18 22:39:14","TRTEDTM":"2022-08-18 16:39:14","TRT01SDTM":"2019-08-18 22:39:14","TRT01EDTM":"2021-08-18 10:39:14","TRT02SDTM":"2021-08-18 10:39:14","TRT02EDTM":"2022-08-18 16:39:14","AP01SDTM":"2019-08-18 22:39:14","AP01EDTM":"2021-08-18 10:39:14","AP02SDTM":"2021-08-18 10:39:14","AP02EDTM":"2022-08-18 16:39:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-18","EOSDY":1096,"LSTALVDT":"2022-09-07","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3948,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99106,"AVALU":"g/L","BASE2":2.99106,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-11 22:39:14","ADY":24,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-114","SUBJID":"id-114","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.10419,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-16","TRTSDTM":"2019-08-18 22:39:14","TRTEDTM":"2022-08-18 16:39:14","TRT01SDTM":"2019-08-18 22:39:14","TRT01EDTM":"2021-08-18 10:39:14","TRT02SDTM":"2021-08-18 10:39:14","TRT02EDTM":"2022-08-18 16:39:14","AP01SDTM":"2019-08-18 22:39:14","AP01EDTM":"2021-08-18 10:39:14","AP02SDTM":"2021-08-18 10:39:14","AP02EDTM":"2022-08-18 16:39:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-18","EOSDY":1096,"LSTALVDT":"2022-09-07","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5976,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94944,"AVALU":"g/L","BASE2":2.99106,"BASE":2.94944,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.04162,"PCHG2":-1.39136,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-02 22:39:14","ADY":137,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-114","SUBJID":"id-114","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.10419,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-16","TRTSDTM":"2019-08-18 22:39:14","TRTEDTM":"2022-08-18 16:39:14","TRT01SDTM":"2019-08-18 22:39:14","TRT01EDTM":"2021-08-18 10:39:14","TRT02SDTM":"2021-08-18 10:39:14","TRT02EDTM":"2022-08-18 16:39:14","AP01SDTM":"2019-08-18 22:39:14","AP01EDTM":"2021-08-18 10:39:14","AP02SDTM":"2021-08-18 10:39:14","AP02EDTM":"2022-08-18 16:39:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-18","EOSDY":1096,"LSTALVDT":"2022-09-07","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2201,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95846,"AVALU":"g/L","BASE2":2.99106,"BASE":2.94944,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0326,"PCHG2":-1.08988,"CHG":0.00902,"PCHG":0.30573,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-18 22:39:14","ADY":184,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-114","SUBJID":"id-114","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.10419,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-16","TRTSDTM":"2019-08-18 22:39:14","TRTEDTM":"2022-08-18 16:39:14","TRT01SDTM":"2019-08-18 22:39:14","TRT01EDTM":"2021-08-18 10:39:14","TRT02SDTM":"2021-08-18 10:39:14","TRT02EDTM":"2022-08-18 16:39:14","AP01SDTM":"2019-08-18 22:39:14","AP01EDTM":"2021-08-18 10:39:14","AP02SDTM":"2021-08-18 10:39:14","AP02EDTM":"2022-08-18 16:39:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-18","EOSDY":1096,"LSTALVDT":"2022-09-07","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7698,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96431,"AVALU":"g/L","BASE2":2.99106,"BASE":2.94944,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02675,"PCHG2":-0.89421,"CHG":0.01487,"PCHG":0.50417,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-08 22:39:14","ADY":203,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-114","SUBJID":"id-114","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.10419,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-16","TRTSDTM":"2019-08-18 22:39:14","TRTEDTM":"2022-08-18 16:39:14","TRT01SDTM":"2019-08-18 22:39:14","TRT01EDTM":"2021-08-18 10:39:14","TRT02SDTM":"2021-08-18 10:39:14","TRT02EDTM":"2022-08-18 16:39:14","AP01SDTM":"2019-08-18 22:39:14","AP01EDTM":"2021-08-18 10:39:14","AP02SDTM":"2021-08-18 10:39:14","AP02EDTM":"2022-08-18 16:39:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-18","EOSDY":1096,"LSTALVDT":"2022-09-07","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1406,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77946,"AVALU":"g/L","BASE2":2.99106,"BASE":2.94944,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.2116,"PCHG2":-7.07441,"CHG":-0.16998,"PCHG":-5.76324,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-21 22:39:14","ADY":216,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-114","SUBJID":"id-114","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.10419,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-16","TRTSDTM":"2019-08-18 22:39:14","TRTEDTM":"2022-08-18 16:39:14","TRT01SDTM":"2019-08-18 22:39:14","TRT01EDTM":"2021-08-18 10:39:14","TRT02SDTM":"2021-08-18 10:39:14","TRT02EDTM":"2022-08-18 16:39:14","AP01SDTM":"2019-08-18 22:39:14","AP01EDTM":"2021-08-18 10:39:14","AP02SDTM":"2021-08-18 10:39:14","AP02EDTM":"2022-08-18 16:39:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-18","EOSDY":1096,"LSTALVDT":"2022-09-07","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6865,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96468,"AVALU":"g/L","BASE2":2.99106,"BASE":2.94944,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02637,"PCHG2":-0.88176,"CHG":0.01524,"PCHG":0.51679,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-28 22:39:14","ADY":710,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-114","SUBJID":"id-114","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.10419,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-16","TRTSDTM":"2019-08-18 22:39:14","TRTEDTM":"2022-08-18 16:39:14","TRT01SDTM":"2019-08-18 22:39:14","TRT01EDTM":"2021-08-18 10:39:14","TRT02SDTM":"2021-08-18 10:39:14","TRT02EDTM":"2022-08-18 16:39:14","AP01SDTM":"2019-08-18 22:39:14","AP01EDTM":"2021-08-18 10:39:14","AP02SDTM":"2021-08-18 10:39:14","AP02EDTM":"2022-08-18 16:39:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-18","EOSDY":1096,"LSTALVDT":"2022-09-07","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2813,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05153,"AVALU":"g/L","BASE2":2.99106,"BASE":2.94944,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06047,"PCHG2":2.0218,"CHG":0.10209,"PCHG":3.46132,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-05-20 22:39:14","ADY":1006,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-115","SUBJID":"id-115","SITEID":"CHN-4","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.00519,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-26","TRTSDTM":"2019-03-28 09:33:43","TRTEDTM":"2022-03-28 03:33:43","TRT01SDTM":"2019-03-28 09:33:43","TRT01EDTM":"2021-03-27 21:33:43","TRT02SDTM":"2021-03-27 21:33:43","TRT02EDTM":"2022-03-28 03:33:43","AP01SDTM":"2019-03-28 09:33:43","AP01EDTM":"2021-03-27 21:33:43","AP02SDTM":"2021-03-27 21:33:43","AP02EDTM":"2022-03-28 03:33:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-28","EOSDY":1096,"LSTALVDT":"2022-04-09","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1549,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.43836,"AVALU":"U/L","BASE2":27.43836,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-04 09:33:43","ADY":190,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-115","SUBJID":"id-115","SITEID":"CHN-4","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.00519,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-26","TRTSDTM":"2019-03-28 09:33:43","TRTEDTM":"2022-03-28 03:33:43","TRT01SDTM":"2019-03-28 09:33:43","TRT01EDTM":"2021-03-27 21:33:43","TRT02SDTM":"2021-03-27 21:33:43","TRT02EDTM":"2022-03-28 03:33:43","AP01SDTM":"2019-03-28 09:33:43","AP01EDTM":"2021-03-27 21:33:43","AP02SDTM":"2021-03-27 21:33:43","AP02EDTM":"2022-03-28 03:33:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-28","EOSDY":1096,"LSTALVDT":"2022-04-09","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4677,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.0884,"AVALU":"U/L","BASE2":27.43836,"BASE":15.0884,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-12.34996,"PCHG2":-45.00984,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-30 09:33:43","ADY":277,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-115","SUBJID":"id-115","SITEID":"CHN-4","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.00519,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-26","TRTSDTM":"2019-03-28 09:33:43","TRTEDTM":"2022-03-28 03:33:43","TRT01SDTM":"2019-03-28 09:33:43","TRT01EDTM":"2021-03-27 21:33:43","TRT02SDTM":"2021-03-27 21:33:43","TRT02EDTM":"2022-03-28 03:33:43","AP01SDTM":"2019-03-28 09:33:43","AP01EDTM":"2021-03-27 21:33:43","AP02SDTM":"2021-03-27 21:33:43","AP02EDTM":"2022-03-28 03:33:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-28","EOSDY":1096,"LSTALVDT":"2022-04-09","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1945,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.43689,"AVALU":"U/L","BASE2":27.43836,"BASE":15.0884,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.00147,"PCHG2":-47.38429,"CHG":-0.65151,"PCHG":-4.31795,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-31 09:33:43","ADY":278,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-115","SUBJID":"id-115","SITEID":"CHN-4","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.00519,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-26","TRTSDTM":"2019-03-28 09:33:43","TRTEDTM":"2022-03-28 03:33:43","TRT01SDTM":"2019-03-28 09:33:43","TRT01EDTM":"2021-03-27 21:33:43","TRT02SDTM":"2021-03-27 21:33:43","TRT02EDTM":"2022-03-28 03:33:43","AP01SDTM":"2019-03-28 09:33:43","AP01EDTM":"2021-03-27 21:33:43","AP02SDTM":"2021-03-27 21:33:43","AP02EDTM":"2022-03-28 03:33:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-28","EOSDY":1096,"LSTALVDT":"2022-04-09","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":708,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.64908,"AVALU":"U/L","BASE2":27.43836,"BASE":15.0884,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.78929,"PCHG2":-42.96644,"CHG":0.56068,"PCHG":3.71595,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-20 09:33:43","ADY":572,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-115","SUBJID":"id-115","SITEID":"CHN-4","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.00519,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-26","TRTSDTM":"2019-03-28 09:33:43","TRTEDTM":"2022-03-28 03:33:43","TRT01SDTM":"2019-03-28 09:33:43","TRT01EDTM":"2021-03-27 21:33:43","TRT02SDTM":"2021-03-27 21:33:43","TRT02EDTM":"2022-03-28 03:33:43","AP01SDTM":"2019-03-28 09:33:43","AP01EDTM":"2021-03-27 21:33:43","AP02SDTM":"2021-03-27 21:33:43","AP02EDTM":"2022-03-28 03:33:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-28","EOSDY":1096,"LSTALVDT":"2022-04-09","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":248,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.01887,"AVALU":"U/L","BASE2":27.43836,"BASE":15.0884,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-24.41949,"PCHG2":-88.99764,"CHG":-12.06953,"PCHG":-79.99213,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-05-29 09:33:43","ADY":793,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-115","SUBJID":"id-115","SITEID":"CHN-4","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.00519,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-26","TRTSDTM":"2019-03-28 09:33:43","TRTEDTM":"2022-03-28 03:33:43","TRT01SDTM":"2019-03-28 09:33:43","TRT01EDTM":"2021-03-27 21:33:43","TRT02SDTM":"2021-03-27 21:33:43","TRT02EDTM":"2022-03-28 03:33:43","AP01SDTM":"2019-03-28 09:33:43","AP01EDTM":"2021-03-27 21:33:43","AP02SDTM":"2021-03-27 21:33:43","AP02EDTM":"2022-03-28 03:33:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-28","EOSDY":1096,"LSTALVDT":"2022-04-09","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":542,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.46954,"AVALU":"U/L","BASE2":27.43836,"BASE":15.0884,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.03117,"PCHG2":18.33628,"CHG":17.38114,"PCHG":115.19538,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-03 09:33:43","ADY":828,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-115","SUBJID":"id-115","SITEID":"CHN-4","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.00519,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-26","TRTSDTM":"2019-03-28 09:33:43","TRTEDTM":"2022-03-28 03:33:43","TRT01SDTM":"2019-03-28 09:33:43","TRT01EDTM":"2021-03-27 21:33:43","TRT02SDTM":"2021-03-27 21:33:43","TRT02EDTM":"2022-03-28 03:33:43","AP01SDTM":"2019-03-28 09:33:43","AP01EDTM":"2021-03-27 21:33:43","AP02SDTM":"2021-03-27 21:33:43","AP02EDTM":"2022-03-28 03:33:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-28","EOSDY":1096,"LSTALVDT":"2022-04-09","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6493,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.49583,"AVALU":"U/L","BASE2":27.43836,"BASE":15.0884,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-22.94253,"PCHG2":-83.6148,"CHG":-10.59257,"PCHG":-70.20339,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-08-24 09:33:43","ADY":880,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-115","SUBJID":"id-115","SITEID":"CHN-4","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.00519,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-26","TRTSDTM":"2019-03-28 09:33:43","TRTEDTM":"2022-03-28 03:33:43","TRT01SDTM":"2019-03-28 09:33:43","TRT01EDTM":"2021-03-27 21:33:43","TRT02SDTM":"2021-03-27 21:33:43","TRT02EDTM":"2022-03-28 03:33:43","AP01SDTM":"2019-03-28 09:33:43","AP01EDTM":"2021-03-27 21:33:43","AP02SDTM":"2021-03-27 21:33:43","AP02EDTM":"2022-03-28 03:33:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-28","EOSDY":1096,"LSTALVDT":"2022-04-09","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4224,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.97541,"AVALU":"mg/L","BASE2":8.97541,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-04 09:33:43","ADY":190,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-115","SUBJID":"id-115","SITEID":"CHN-4","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.00519,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-26","TRTSDTM":"2019-03-28 09:33:43","TRTEDTM":"2022-03-28 03:33:43","TRT01SDTM":"2019-03-28 09:33:43","TRT01EDTM":"2021-03-27 21:33:43","TRT02SDTM":"2021-03-27 21:33:43","TRT02EDTM":"2022-03-28 03:33:43","AP01SDTM":"2019-03-28 09:33:43","AP01EDTM":"2021-03-27 21:33:43","AP02SDTM":"2021-03-27 21:33:43","AP02EDTM":"2022-03-28 03:33:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-28","EOSDY":1096,"LSTALVDT":"2022-04-09","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3745,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.90056,"AVALU":"mg/L","BASE2":8.97541,"BASE":8.90056,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.07485,"PCHG2":-0.83395,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-30 09:33:43","ADY":277,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-115","SUBJID":"id-115","SITEID":"CHN-4","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.00519,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-26","TRTSDTM":"2019-03-28 09:33:43","TRTEDTM":"2022-03-28 03:33:43","TRT01SDTM":"2019-03-28 09:33:43","TRT01EDTM":"2021-03-27 21:33:43","TRT02SDTM":"2021-03-27 21:33:43","TRT02EDTM":"2022-03-28 03:33:43","AP01SDTM":"2019-03-28 09:33:43","AP01EDTM":"2021-03-27 21:33:43","AP02SDTM":"2021-03-27 21:33:43","AP02EDTM":"2022-03-28 03:33:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-28","EOSDY":1096,"LSTALVDT":"2022-04-09","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1920,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.82992,"AVALU":"mg/L","BASE2":8.97541,"BASE":8.90056,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.85451,"PCHG2":9.52054,"CHG":0.92936,"PCHG":10.44156,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-31 09:33:43","ADY":278,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-115","SUBJID":"id-115","SITEID":"CHN-4","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.00519,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-26","TRTSDTM":"2019-03-28 09:33:43","TRTEDTM":"2022-03-28 03:33:43","TRT01SDTM":"2019-03-28 09:33:43","TRT01EDTM":"2021-03-27 21:33:43","TRT02SDTM":"2021-03-27 21:33:43","TRT02EDTM":"2022-03-28 03:33:43","AP01SDTM":"2019-03-28 09:33:43","AP01EDTM":"2021-03-27 21:33:43","AP02SDTM":"2021-03-27 21:33:43","AP02EDTM":"2022-03-28 03:33:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-28","EOSDY":1096,"LSTALVDT":"2022-04-09","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3481,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.48208,"AVALU":"mg/L","BASE2":8.97541,"BASE":8.90056,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.50666,"PCHG2":5.64503,"CHG":0.58151,"PCHG":6.53346,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-20 09:33:43","ADY":572,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-115","SUBJID":"id-115","SITEID":"CHN-4","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.00519,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-26","TRTSDTM":"2019-03-28 09:33:43","TRTEDTM":"2022-03-28 03:33:43","TRT01SDTM":"2019-03-28 09:33:43","TRT01EDTM":"2021-03-27 21:33:43","TRT02SDTM":"2021-03-27 21:33:43","TRT02EDTM":"2022-03-28 03:33:43","AP01SDTM":"2019-03-28 09:33:43","AP01EDTM":"2021-03-27 21:33:43","AP02SDTM":"2021-03-27 21:33:43","AP02EDTM":"2022-03-28 03:33:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-28","EOSDY":1096,"LSTALVDT":"2022-04-09","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8292,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.88314,"AVALU":"mg/L","BASE2":8.97541,"BASE":8.90056,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09227,"PCHG2":-1.02804,"CHG":-0.01742,"PCHG":-0.19573,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-29 09:33:43","ADY":793,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-115","SUBJID":"id-115","SITEID":"CHN-4","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.00519,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-26","TRTSDTM":"2019-03-28 09:33:43","TRTEDTM":"2022-03-28 03:33:43","TRT01SDTM":"2019-03-28 09:33:43","TRT01EDTM":"2021-03-27 21:33:43","TRT02SDTM":"2021-03-27 21:33:43","TRT02EDTM":"2022-03-28 03:33:43","AP01SDTM":"2019-03-28 09:33:43","AP01EDTM":"2021-03-27 21:33:43","AP02SDTM":"2021-03-27 21:33:43","AP02EDTM":"2022-03-28 03:33:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-28","EOSDY":1096,"LSTALVDT":"2022-04-09","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1775,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.59695,"AVALU":"mg/L","BASE2":8.97541,"BASE":8.90056,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.62154,"PCHG2":6.92493,"CHG":0.69639,"PCHG":7.82412,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-03 09:33:43","ADY":828,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-115","SUBJID":"id-115","SITEID":"CHN-4","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.00519,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-26","TRTSDTM":"2019-03-28 09:33:43","TRTEDTM":"2022-03-28 03:33:43","TRT01SDTM":"2019-03-28 09:33:43","TRT01EDTM":"2021-03-27 21:33:43","TRT02SDTM":"2021-03-27 21:33:43","TRT02EDTM":"2022-03-28 03:33:43","AP01SDTM":"2019-03-28 09:33:43","AP01EDTM":"2021-03-27 21:33:43","AP02SDTM":"2021-03-27 21:33:43","AP02EDTM":"2022-03-28 03:33:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-28","EOSDY":1096,"LSTALVDT":"2022-04-09","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4125,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.90834,"AVALU":"mg/L","BASE2":8.97541,"BASE":8.90056,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06707,"PCHG2":-0.74721,"CHG":0.00778,"PCHG":0.08746,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-24 09:33:43","ADY":880,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-115","SUBJID":"id-115","SITEID":"CHN-4","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.00519,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-26","TRTSDTM":"2019-03-28 09:33:43","TRTEDTM":"2022-03-28 03:33:43","TRT01SDTM":"2019-03-28 09:33:43","TRT01EDTM":"2021-03-27 21:33:43","TRT02SDTM":"2021-03-27 21:33:43","TRT02EDTM":"2022-03-28 03:33:43","AP01SDTM":"2019-03-28 09:33:43","AP01EDTM":"2021-03-27 21:33:43","AP02SDTM":"2021-03-27 21:33:43","AP02EDTM":"2022-03-28 03:33:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-28","EOSDY":1096,"LSTALVDT":"2022-04-09","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7198,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91858,"AVALU":"g/L","BASE2":2.91858,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2019-10-04 09:33:43","ADY":190,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-115","SUBJID":"id-115","SITEID":"CHN-4","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.00519,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-26","TRTSDTM":"2019-03-28 09:33:43","TRTEDTM":"2022-03-28 03:33:43","TRT01SDTM":"2019-03-28 09:33:43","TRT01EDTM":"2021-03-27 21:33:43","TRT02SDTM":"2021-03-27 21:33:43","TRT02EDTM":"2022-03-28 03:33:43","AP01SDTM":"2019-03-28 09:33:43","AP01EDTM":"2021-03-27 21:33:43","AP02SDTM":"2021-03-27 21:33:43","AP02EDTM":"2022-03-28 03:33:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-28","EOSDY":1096,"LSTALVDT":"2022-04-09","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7721,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.14113,"AVALU":"g/L","BASE2":2.91858,"BASE":3.14113,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.22255,"PCHG2":7.62526,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2019-12-30 09:33:43","ADY":277,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-115","SUBJID":"id-115","SITEID":"CHN-4","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.00519,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-26","TRTSDTM":"2019-03-28 09:33:43","TRTEDTM":"2022-03-28 03:33:43","TRT01SDTM":"2019-03-28 09:33:43","TRT01EDTM":"2021-03-27 21:33:43","TRT02SDTM":"2021-03-27 21:33:43","TRT02EDTM":"2022-03-28 03:33:43","AP01SDTM":"2019-03-28 09:33:43","AP01EDTM":"2021-03-27 21:33:43","AP02SDTM":"2021-03-27 21:33:43","AP02EDTM":"2022-03-28 03:33:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-28","EOSDY":1096,"LSTALVDT":"2022-04-09","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2913,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.06698,"AVALU":"g/L","BASE2":2.91858,"BASE":3.14113,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1484,"PCHG2":5.08468,"CHG":-0.07415,"PCHG":-2.36058,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"3","ADTM":"2019-12-31 09:33:43","ADY":278,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-115","SUBJID":"id-115","SITEID":"CHN-4","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.00519,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-26","TRTSDTM":"2019-03-28 09:33:43","TRTEDTM":"2022-03-28 03:33:43","TRT01SDTM":"2019-03-28 09:33:43","TRT01EDTM":"2021-03-27 21:33:43","TRT02SDTM":"2021-03-27 21:33:43","TRT02EDTM":"2022-03-28 03:33:43","AP01SDTM":"2019-03-28 09:33:43","AP01EDTM":"2021-03-27 21:33:43","AP02SDTM":"2021-03-27 21:33:43","AP02EDTM":"2022-03-28 03:33:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-28","EOSDY":1096,"LSTALVDT":"2022-04-09","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7380,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86568,"AVALU":"g/L","BASE2":2.91858,"BASE":3.14113,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0529,"PCHG2":-1.81262,"CHG":-0.27545,"PCHG":-8.7692,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-10-20 09:33:43","ADY":572,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-115","SUBJID":"id-115","SITEID":"CHN-4","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.00519,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-26","TRTSDTM":"2019-03-28 09:33:43","TRTEDTM":"2022-03-28 03:33:43","TRT01SDTM":"2019-03-28 09:33:43","TRT01EDTM":"2021-03-27 21:33:43","TRT02SDTM":"2021-03-27 21:33:43","TRT02EDTM":"2022-03-28 03:33:43","AP01SDTM":"2019-03-28 09:33:43","AP01EDTM":"2021-03-27 21:33:43","AP02SDTM":"2021-03-27 21:33:43","AP02EDTM":"2022-03-28 03:33:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-28","EOSDY":1096,"LSTALVDT":"2022-04-09","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3971,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89745,"AVALU":"g/L","BASE2":2.91858,"BASE":3.14113,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02113,"PCHG2":-0.72397,"CHG":-0.24368,"PCHG":-7.75768,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-05-29 09:33:43","ADY":793,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-115","SUBJID":"id-115","SITEID":"CHN-4","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.00519,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-26","TRTSDTM":"2019-03-28 09:33:43","TRTEDTM":"2022-03-28 03:33:43","TRT01SDTM":"2019-03-28 09:33:43","TRT01EDTM":"2021-03-27 21:33:43","TRT02SDTM":"2021-03-27 21:33:43","TRT02EDTM":"2022-03-28 03:33:43","AP01SDTM":"2019-03-28 09:33:43","AP01EDTM":"2021-03-27 21:33:43","AP02SDTM":"2021-03-27 21:33:43","AP02EDTM":"2022-03-28 03:33:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-28","EOSDY":1096,"LSTALVDT":"2022-04-09","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6206,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03404,"AVALU":"g/L","BASE2":2.91858,"BASE":3.14113,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11546,"PCHG2":3.956,"CHG":-0.10709,"PCHG":-3.40929,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"4","BTOXGR":"3","ADTM":"2021-07-03 09:33:43","ADY":828,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-115","SUBJID":"id-115","SITEID":"CHN-4","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.00519,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-26","TRTSDTM":"2019-03-28 09:33:43","TRTEDTM":"2022-03-28 03:33:43","TRT01SDTM":"2019-03-28 09:33:43","TRT01EDTM":"2021-03-27 21:33:43","TRT02SDTM":"2021-03-27 21:33:43","TRT02EDTM":"2022-03-28 03:33:43","AP01SDTM":"2019-03-28 09:33:43","AP01EDTM":"2021-03-27 21:33:43","AP02SDTM":"2021-03-27 21:33:43","AP02EDTM":"2022-03-28 03:33:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-28","EOSDY":1096,"LSTALVDT":"2022-04-09","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2464,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87465,"AVALU":"g/L","BASE2":2.91858,"BASE":3.14113,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04393,"PCHG2":-1.50532,"CHG":-0.26648,"PCHG":-8.48367,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-08-24 09:33:43","ADY":880,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-122","SUBJID":"id-122","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.85899,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-21 08:08:52","TRTEDTM":"2022-02-15 23:16:33","TRT01SDTM":"2019-12-21 08:08:52","TRT01EDTM":"2021-02-15 17:16:33","TRT02SDTM":"2021-02-15 17:16:33","TRT02EDTM":"2022-02-15 23:16:33","AP01SDTM":"2019-12-21 08:08:52","AP01EDTM":"2021-02-15 17:16:33","AP02SDTM":"2021-02-15 17:16:33","AP02EDTM":"2022-02-15 23:16:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":788,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-05","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1091,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.00029,"AVALU":"U/L","BASE2":28.00029,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-3","ADTM":"2020-02-10 08:08:52","ADY":51,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-122","SUBJID":"id-122","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.85899,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-21 08:08:52","TRTEDTM":"2022-02-15 23:16:33","TRT01SDTM":"2019-12-21 08:08:52","TRT01EDTM":"2021-02-15 17:16:33","TRT02SDTM":"2021-02-15 17:16:33","TRT02EDTM":"2022-02-15 23:16:33","AP01SDTM":"2019-12-21 08:08:52","AP01EDTM":"2021-02-15 17:16:33","AP02SDTM":"2021-02-15 17:16:33","AP02EDTM":"2022-02-15 23:16:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":788,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-05","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4427,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.28751,"AVALU":"U/L","BASE2":28.00029,"BASE":6.28751,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-21.71277,"PCHG2":-77.54483,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2020-03-05 08:08:52","ADY":75,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-122","SUBJID":"id-122","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.85899,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-21 08:08:52","TRTEDTM":"2022-02-15 23:16:33","TRT01SDTM":"2019-12-21 08:08:52","TRT01EDTM":"2021-02-15 17:16:33","TRT02SDTM":"2021-02-15 17:16:33","TRT02EDTM":"2022-02-15 23:16:33","AP01SDTM":"2019-12-21 08:08:52","AP01EDTM":"2021-02-15 17:16:33","AP02SDTM":"2021-02-15 17:16:33","AP02EDTM":"2022-02-15 23:16:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":788,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-05","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6929,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.15579,"AVALU":"U/L","BASE2":28.00029,"BASE":6.28751,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.8445,"PCHG2":-45.87274,"CHG":8.86828,"PCHG":141.04583,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2020-05-06 08:08:52","ADY":137,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-122","SUBJID":"id-122","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.85899,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-21 08:08:52","TRTEDTM":"2022-02-15 23:16:33","TRT01SDTM":"2019-12-21 08:08:52","TRT01EDTM":"2021-02-15 17:16:33","TRT02SDTM":"2021-02-15 17:16:33","TRT02EDTM":"2022-02-15 23:16:33","AP01SDTM":"2019-12-21 08:08:52","AP01EDTM":"2021-02-15 17:16:33","AP02SDTM":"2021-02-15 17:16:33","AP02EDTM":"2022-02-15 23:16:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":788,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-05","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2250,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.77901,"AVALU":"U/L","BASE2":28.00029,"BASE":6.28751,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-26.22128,"PCHG2":-93.64645,"CHG":-4.5085,"PCHG":-71.70565,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2020-05-26 08:08:52","ADY":157,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-122","SUBJID":"id-122","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.85899,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-21 08:08:52","TRTEDTM":"2022-02-15 23:16:33","TRT01SDTM":"2019-12-21 08:08:52","TRT01EDTM":"2021-02-15 17:16:33","TRT02SDTM":"2021-02-15 17:16:33","TRT02EDTM":"2022-02-15 23:16:33","AP01SDTM":"2019-12-21 08:08:52","AP01EDTM":"2021-02-15 17:16:33","AP02SDTM":"2021-02-15 17:16:33","AP02EDTM":"2022-02-15 23:16:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":788,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-05","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4063,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.19475,"AVALU":"U/L","BASE2":28.00029,"BASE":6.28751,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-27.80554,"PCHG2":-99.30447,"CHG":-6.09276,"PCHG":-96.9026,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-3","ADTM":"2021-03-29 08:08:52","ADY":464,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-122","SUBJID":"id-122","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.85899,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-21 08:08:52","TRTEDTM":"2022-02-15 23:16:33","TRT01SDTM":"2019-12-21 08:08:52","TRT01EDTM":"2021-02-15 17:16:33","TRT02SDTM":"2021-02-15 17:16:33","TRT02EDTM":"2022-02-15 23:16:33","AP01SDTM":"2019-12-21 08:08:52","AP01EDTM":"2021-02-15 17:16:33","AP02SDTM":"2021-02-15 17:16:33","AP02EDTM":"2022-02-15 23:16:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":788,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-05","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8297,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.31313,"AVALU":"U/L","BASE2":28.00029,"BASE":6.28751,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.68716,"PCHG2":-59.59639,"CHG":5.02561,"PCHG":79.93004,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-06-18 08:08:52","ADY":545,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-122","SUBJID":"id-122","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.85899,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-21 08:08:52","TRTEDTM":"2022-02-15 23:16:33","TRT01SDTM":"2019-12-21 08:08:52","TRT01EDTM":"2021-02-15 17:16:33","TRT02SDTM":"2021-02-15 17:16:33","TRT02EDTM":"2022-02-15 23:16:33","AP01SDTM":"2019-12-21 08:08:52","AP01EDTM":"2021-02-15 17:16:33","AP02SDTM":"2021-02-15 17:16:33","AP02EDTM":"2022-02-15 23:16:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":788,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-05","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5913,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.56513,"AVALU":"U/L","BASE2":28.00029,"BASE":6.28751,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.43516,"PCHG2":-47.98221,"CHG":8.27762,"PCHG":131.6517,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-12-30 08:08:52","ADY":740,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-122","SUBJID":"id-122","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.85899,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-21 08:08:52","TRTEDTM":"2022-02-15 23:16:33","TRT01SDTM":"2019-12-21 08:08:52","TRT01EDTM":"2021-02-15 17:16:33","TRT02SDTM":"2021-02-15 17:16:33","TRT02EDTM":"2022-02-15 23:16:33","AP01SDTM":"2019-12-21 08:08:52","AP01EDTM":"2021-02-15 17:16:33","AP02SDTM":"2021-02-15 17:16:33","AP02EDTM":"2022-02-15 23:16:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":788,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-05","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4935,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.09922,"AVALU":"mg/L","BASE2":7.09922,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2020-02-10 08:08:52","ADY":51,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-122","SUBJID":"id-122","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.85899,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-21 08:08:52","TRTEDTM":"2022-02-15 23:16:33","TRT01SDTM":"2019-12-21 08:08:52","TRT01EDTM":"2021-02-15 17:16:33","TRT02SDTM":"2021-02-15 17:16:33","TRT02EDTM":"2022-02-15 23:16:33","AP01SDTM":"2019-12-21 08:08:52","AP01EDTM":"2021-02-15 17:16:33","AP02SDTM":"2021-02-15 17:16:33","AP02EDTM":"2022-02-15 23:16:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":788,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-05","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2118,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.49528,"AVALU":"mg/L","BASE2":7.09922,"BASE":7.49528,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.39605,"PCHG2":5.5788,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2020-03-05 08:08:52","ADY":75,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-122","SUBJID":"id-122","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.85899,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-21 08:08:52","TRTEDTM":"2022-02-15 23:16:33","TRT01SDTM":"2019-12-21 08:08:52","TRT01EDTM":"2021-02-15 17:16:33","TRT02SDTM":"2021-02-15 17:16:33","TRT02EDTM":"2022-02-15 23:16:33","AP01SDTM":"2019-12-21 08:08:52","AP01EDTM":"2021-02-15 17:16:33","AP02SDTM":"2021-02-15 17:16:33","AP02EDTM":"2022-02-15 23:16:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":788,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-05","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6253,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.92012,"AVALU":"mg/L","BASE2":7.09922,"BASE":7.49528,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.8209,"PCHG2":25.64927,"CHG":1.42485,"PCHG":19.00995,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2020-05-06 08:08:52","ADY":137,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-122","SUBJID":"id-122","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.85899,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-21 08:08:52","TRTEDTM":"2022-02-15 23:16:33","TRT01SDTM":"2019-12-21 08:08:52","TRT01EDTM":"2021-02-15 17:16:33","TRT02SDTM":"2021-02-15 17:16:33","TRT02EDTM":"2022-02-15 23:16:33","AP01SDTM":"2019-12-21 08:08:52","AP01EDTM":"2021-02-15 17:16:33","AP02SDTM":"2021-02-15 17:16:33","AP02EDTM":"2022-02-15 23:16:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":788,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-05","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7218,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.06027,"AVALU":"mg/L","BASE2":7.09922,"BASE":7.49528,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.96104,"PCHG2":13.5373,"CHG":0.56499,"PCHG":7.53797,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2020-05-26 08:08:52","ADY":157,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-122","SUBJID":"id-122","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.85899,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-21 08:08:52","TRTEDTM":"2022-02-15 23:16:33","TRT01SDTM":"2019-12-21 08:08:52","TRT01EDTM":"2021-02-15 17:16:33","TRT02SDTM":"2021-02-15 17:16:33","TRT02EDTM":"2022-02-15 23:16:33","AP01SDTM":"2019-12-21 08:08:52","AP01EDTM":"2021-02-15 17:16:33","AP02SDTM":"2021-02-15 17:16:33","AP02EDTM":"2022-02-15 23:16:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":788,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-05","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7641,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.35085,"AVALU":"mg/L","BASE2":7.09922,"BASE":7.49528,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.25163,"PCHG2":31.71649,"CHG":1.85557,"PCHG":24.75658,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-03-29 08:08:52","ADY":464,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-122","SUBJID":"id-122","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.85899,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-21 08:08:52","TRTEDTM":"2022-02-15 23:16:33","TRT01SDTM":"2019-12-21 08:08:52","TRT01EDTM":"2021-02-15 17:16:33","TRT02SDTM":"2021-02-15 17:16:33","TRT02EDTM":"2022-02-15 23:16:33","AP01SDTM":"2019-12-21 08:08:52","AP01EDTM":"2021-02-15 17:16:33","AP02SDTM":"2021-02-15 17:16:33","AP02EDTM":"2022-02-15 23:16:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":788,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-05","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2198,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.39577,"AVALU":"mg/L","BASE2":7.09922,"BASE":7.49528,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.29655,"PCHG2":18.26321,"CHG":0.90049,"PCHG":12.01417,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-06-18 08:08:52","ADY":545,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-122","SUBJID":"id-122","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.85899,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-21 08:08:52","TRTEDTM":"2022-02-15 23:16:33","TRT01SDTM":"2019-12-21 08:08:52","TRT01EDTM":"2021-02-15 17:16:33","TRT02SDTM":"2021-02-15 17:16:33","TRT02EDTM":"2022-02-15 23:16:33","AP01SDTM":"2019-12-21 08:08:52","AP01EDTM":"2021-02-15 17:16:33","AP02SDTM":"2021-02-15 17:16:33","AP02EDTM":"2022-02-15 23:16:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":788,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-05","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6949,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.26958,"AVALU":"mg/L","BASE2":7.09922,"BASE":7.49528,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.17036,"PCHG2":30.57178,"CHG":1.77431,"PCHG":23.67235,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-12-30 08:08:52","ADY":740,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-122","SUBJID":"id-122","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.85899,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-21 08:08:52","TRTEDTM":"2022-02-15 23:16:33","TRT01SDTM":"2019-12-21 08:08:52","TRT01EDTM":"2021-02-15 17:16:33","TRT02SDTM":"2021-02-15 17:16:33","TRT02EDTM":"2022-02-15 23:16:33","AP01SDTM":"2019-12-21 08:08:52","AP01EDTM":"2021-02-15 17:16:33","AP02SDTM":"2021-02-15 17:16:33","AP02EDTM":"2022-02-15 23:16:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":788,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-05","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7930,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82712,"AVALU":"g/L","BASE2":2.82712,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-10 08:08:52","ADY":51,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-122","SUBJID":"id-122","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.85899,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-21 08:08:52","TRTEDTM":"2022-02-15 23:16:33","TRT01SDTM":"2019-12-21 08:08:52","TRT01EDTM":"2021-02-15 17:16:33","TRT02SDTM":"2021-02-15 17:16:33","TRT02EDTM":"2022-02-15 23:16:33","AP01SDTM":"2019-12-21 08:08:52","AP01EDTM":"2021-02-15 17:16:33","AP02SDTM":"2021-02-15 17:16:33","AP02EDTM":"2022-02-15 23:16:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":788,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-05","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3530,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79022,"AVALU":"g/L","BASE2":2.82712,"BASE":2.79022,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.0369,"PCHG2":-1.30514,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-05 08:08:52","ADY":75,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-122","SUBJID":"id-122","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.85899,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-21 08:08:52","TRTEDTM":"2022-02-15 23:16:33","TRT01SDTM":"2019-12-21 08:08:52","TRT01EDTM":"2021-02-15 17:16:33","TRT02SDTM":"2021-02-15 17:16:33","TRT02EDTM":"2022-02-15 23:16:33","AP01SDTM":"2019-12-21 08:08:52","AP01EDTM":"2021-02-15 17:16:33","AP02SDTM":"2021-02-15 17:16:33","AP02EDTM":"2022-02-15 23:16:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":788,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-05","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6076,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97233,"AVALU":"g/L","BASE2":2.82712,"BASE":2.79022,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14521,"PCHG2":5.13635,"CHG":0.18211,"PCHG":6.52667,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-06 08:08:52","ADY":137,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-122","SUBJID":"id-122","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.85899,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-21 08:08:52","TRTEDTM":"2022-02-15 23:16:33","TRT01SDTM":"2019-12-21 08:08:52","TRT01EDTM":"2021-02-15 17:16:33","TRT02SDTM":"2021-02-15 17:16:33","TRT02EDTM":"2022-02-15 23:16:33","AP01SDTM":"2019-12-21 08:08:52","AP01EDTM":"2021-02-15 17:16:33","AP02SDTM":"2021-02-15 17:16:33","AP02EDTM":"2022-02-15 23:16:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":788,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-05","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5893,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.14824,"AVALU":"g/L","BASE2":2.82712,"BASE":2.79022,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.32112,"PCHG2":11.35855,"CHG":0.35802,"PCHG":12.83116,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-05-26 08:08:52","ADY":157,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-122","SUBJID":"id-122","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.85899,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-21 08:08:52","TRTEDTM":"2022-02-15 23:16:33","TRT01SDTM":"2019-12-21 08:08:52","TRT01EDTM":"2021-02-15 17:16:33","TRT02SDTM":"2021-02-15 17:16:33","TRT02EDTM":"2022-02-15 23:16:33","AP01SDTM":"2019-12-21 08:08:52","AP01EDTM":"2021-02-15 17:16:33","AP02SDTM":"2021-02-15 17:16:33","AP02EDTM":"2022-02-15 23:16:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":788,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-05","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5750,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82388,"AVALU":"g/L","BASE2":2.82712,"BASE":2.79022,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00324,"PCHG2":-0.1146,"CHG":0.03366,"PCHG":1.20628,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-29 08:08:52","ADY":464,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-122","SUBJID":"id-122","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.85899,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-21 08:08:52","TRTEDTM":"2022-02-15 23:16:33","TRT01SDTM":"2019-12-21 08:08:52","TRT01EDTM":"2021-02-15 17:16:33","TRT02SDTM":"2021-02-15 17:16:33","TRT02EDTM":"2022-02-15 23:16:33","AP01SDTM":"2019-12-21 08:08:52","AP01EDTM":"2021-02-15 17:16:33","AP02SDTM":"2021-02-15 17:16:33","AP02EDTM":"2022-02-15 23:16:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":788,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-05","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4355,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96683,"AVALU":"g/L","BASE2":2.82712,"BASE":2.79022,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13971,"PCHG2":4.94165,"CHG":0.1766,"PCHG":6.32939,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-18 08:08:52","ADY":545,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-122","SUBJID":"id-122","SITEID":"CHN-4","AGE":23,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.85899,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-21 08:08:52","TRTEDTM":"2022-02-15 23:16:33","TRT01SDTM":"2019-12-21 08:08:52","TRT01EDTM":"2021-02-15 17:16:33","TRT02SDTM":"2021-02-15 17:16:33","TRT02EDTM":"2022-02-15 23:16:33","AP01SDTM":"2019-12-21 08:08:52","AP01EDTM":"2021-02-15 17:16:33","AP02SDTM":"2021-02-15 17:16:33","AP02EDTM":"2022-02-15 23:16:33","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":788,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-05","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":560,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01369,"AVALU":"g/L","BASE2":2.82712,"BASE":2.79022,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18657,"PCHG2":6.59931,"CHG":0.22347,"PCHG":8.00898,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2021-12-30 08:08:52","ADY":740,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-310","SUBJID":"id-310","SITEID":"CHN-4","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.85139,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-20","TRTSDTM":"2019-07-20 12:02:21","TRTEDTM":"2022-07-20 06:02:21","TRT01SDTM":"2019-07-20 12:02:21","TRT01EDTM":"2021-07-20 00:02:21","TRT02SDTM":"2021-07-20 00:02:21","TRT02EDTM":"2022-07-20 06:02:21","AP01SDTM":"2019-07-20 12:02:21","AP01EDTM":"2021-07-20 00:02:21","AP02SDTM":"2021-07-20 00:02:21","AP02EDTM":"2022-07-20 06:02:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6312,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":39.72612,"AVALU":"U/L","BASE2":39.72612,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-01 12:02:21","ADY":286,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-310","SUBJID":"id-310","SITEID":"CHN-4","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.85139,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-20","TRTSDTM":"2019-07-20 12:02:21","TRTEDTM":"2022-07-20 06:02:21","TRT01SDTM":"2019-07-20 12:02:21","TRT01EDTM":"2021-07-20 00:02:21","TRT02SDTM":"2021-07-20 00:02:21","TRT02EDTM":"2022-07-20 06:02:21","AP01SDTM":"2019-07-20 12:02:21","AP01EDTM":"2021-07-20 00:02:21","AP02SDTM":"2021-07-20 00:02:21","AP02EDTM":"2022-07-20 06:02:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":699,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.16168,"AVALU":"U/L","BASE2":39.72612,"BASE":34.16168,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-5.56444,"PCHG2":-14.00701,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-18 12:02:21","ADY":395,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-310","SUBJID":"id-310","SITEID":"CHN-4","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.85139,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-20","TRTSDTM":"2019-07-20 12:02:21","TRTEDTM":"2022-07-20 06:02:21","TRT01SDTM":"2019-07-20 12:02:21","TRT01EDTM":"2021-07-20 00:02:21","TRT02SDTM":"2021-07-20 00:02:21","TRT02EDTM":"2022-07-20 06:02:21","AP01SDTM":"2019-07-20 12:02:21","AP01EDTM":"2021-07-20 00:02:21","AP02SDTM":"2021-07-20 00:02:21","AP02EDTM":"2022-07-20 06:02:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3299,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.53895,"AVALU":"U/L","BASE2":39.72612,"BASE":34.16168,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-36.18716,"PCHG2":-91.09162,"CHG":-30.62272,"PCHG":-89.64058,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-12-08 12:02:21","ADY":507,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-310","SUBJID":"id-310","SITEID":"CHN-4","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.85139,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-20","TRTSDTM":"2019-07-20 12:02:21","TRTEDTM":"2022-07-20 06:02:21","TRT01SDTM":"2019-07-20 12:02:21","TRT01EDTM":"2021-07-20 00:02:21","TRT02SDTM":"2021-07-20 00:02:21","TRT02EDTM":"2022-07-20 06:02:21","AP01SDTM":"2019-07-20 12:02:21","AP01EDTM":"2021-07-20 00:02:21","AP02SDTM":"2021-07-20 00:02:21","AP02EDTM":"2022-07-20 06:02:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3900,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.70347,"AVALU":"U/L","BASE2":39.72612,"BASE":34.16168,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-28.02264,"PCHG2":-70.5396,"CHG":-22.4582,"PCHG":-65.74093,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-07 12:02:21","ADY":537,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-310","SUBJID":"id-310","SITEID":"CHN-4","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.85139,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-20","TRTSDTM":"2019-07-20 12:02:21","TRTEDTM":"2022-07-20 06:02:21","TRT01SDTM":"2019-07-20 12:02:21","TRT01EDTM":"2021-07-20 00:02:21","TRT02SDTM":"2021-07-20 00:02:21","TRT02EDTM":"2022-07-20 06:02:21","AP01SDTM":"2019-07-20 12:02:21","AP01EDTM":"2021-07-20 00:02:21","AP02SDTM":"2021-07-20 00:02:21","AP02EDTM":"2022-07-20 06:02:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":327,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.40197,"AVALU":"U/L","BASE2":39.72612,"BASE":34.16168,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-33.32415,"PCHG2":-83.88474,"CHG":-27.75971,"PCHG":-81.2598,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-09-27 12:02:21","ADY":800,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-310","SUBJID":"id-310","SITEID":"CHN-4","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.85139,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-20","TRTSDTM":"2019-07-20 12:02:21","TRTEDTM":"2022-07-20 06:02:21","TRT01SDTM":"2019-07-20 12:02:21","TRT01EDTM":"2021-07-20 00:02:21","TRT02SDTM":"2021-07-20 00:02:21","TRT02EDTM":"2022-07-20 06:02:21","AP01SDTM":"2019-07-20 12:02:21","AP01EDTM":"2021-07-20 00:02:21","AP02SDTM":"2021-07-20 00:02:21","AP02EDTM":"2022-07-20 06:02:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1004,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.80726,"AVALU":"U/L","BASE2":39.72612,"BASE":34.16168,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-21.91886,"PCHG2":-55.17493,"CHG":-16.35442,"PCHG":-47.87358,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-07 12:02:21","ADY":933,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-310","SUBJID":"id-310","SITEID":"CHN-4","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.85139,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-20","TRTSDTM":"2019-07-20 12:02:21","TRTEDTM":"2022-07-20 06:02:21","TRT01SDTM":"2019-07-20 12:02:21","TRT01EDTM":"2021-07-20 00:02:21","TRT02SDTM":"2021-07-20 00:02:21","TRT02EDTM":"2022-07-20 06:02:21","AP01SDTM":"2019-07-20 12:02:21","AP01EDTM":"2021-07-20 00:02:21","AP02SDTM":"2021-07-20 00:02:21","AP02EDTM":"2022-07-20 06:02:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4791,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.35207,"AVALU":"U/L","BASE2":39.72612,"BASE":34.16168,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.37405,"PCHG2":-23.59669,"CHG":-3.80961,"PCHG":-11.1517,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-05 12:02:21","ADY":959,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-310","SUBJID":"id-310","SITEID":"CHN-4","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.85139,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-20","TRTSDTM":"2019-07-20 12:02:21","TRTEDTM":"2022-07-20 06:02:21","TRT01SDTM":"2019-07-20 12:02:21","TRT01EDTM":"2021-07-20 00:02:21","TRT02SDTM":"2021-07-20 00:02:21","TRT02EDTM":"2022-07-20 06:02:21","AP01SDTM":"2019-07-20 12:02:21","AP01EDTM":"2021-07-20 00:02:21","AP02SDTM":"2021-07-20 00:02:21","AP02EDTM":"2022-07-20 06:02:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3430,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.65111,"AVALU":"mg/L","BASE2":7.65111,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-05-01 12:02:21","ADY":286,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-310","SUBJID":"id-310","SITEID":"CHN-4","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.85139,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-20","TRTSDTM":"2019-07-20 12:02:21","TRTEDTM":"2022-07-20 06:02:21","TRT01SDTM":"2019-07-20 12:02:21","TRT01EDTM":"2021-07-20 00:02:21","TRT02SDTM":"2021-07-20 00:02:21","TRT02EDTM":"2022-07-20 06:02:21","AP01SDTM":"2019-07-20 12:02:21","AP01EDTM":"2021-07-20 00:02:21","AP02SDTM":"2021-07-20 00:02:21","AP02EDTM":"2022-07-20 06:02:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":751,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.60496,"AVALU":"mg/L","BASE2":7.65111,"BASE":8.60496,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.95385,"PCHG2":12.46684,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-18 12:02:21","ADY":395,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-310","SUBJID":"id-310","SITEID":"CHN-4","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.85139,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-20","TRTSDTM":"2019-07-20 12:02:21","TRTEDTM":"2022-07-20 06:02:21","TRT01SDTM":"2019-07-20 12:02:21","TRT01EDTM":"2021-07-20 00:02:21","TRT02SDTM":"2021-07-20 00:02:21","TRT02EDTM":"2022-07-20 06:02:21","AP01SDTM":"2019-07-20 12:02:21","AP01EDTM":"2021-07-20 00:02:21","AP02SDTM":"2021-07-20 00:02:21","AP02EDTM":"2022-07-20 06:02:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7826,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.41557,"AVALU":"mg/L","BASE2":7.65111,"BASE":8.60496,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.76447,"PCHG2":9.99158,"CHG":-0.18939,"PCHG":-2.20088,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-08 12:02:21","ADY":507,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-310","SUBJID":"id-310","SITEID":"CHN-4","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.85139,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-20","TRTSDTM":"2019-07-20 12:02:21","TRTEDTM":"2022-07-20 06:02:21","TRT01SDTM":"2019-07-20 12:02:21","TRT01EDTM":"2021-07-20 00:02:21","TRT02SDTM":"2021-07-20 00:02:21","TRT02EDTM":"2022-07-20 06:02:21","AP01SDTM":"2019-07-20 12:02:21","AP01EDTM":"2021-07-20 00:02:21","AP02SDTM":"2021-07-20 00:02:21","AP02EDTM":"2022-07-20 06:02:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":878,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.1164,"AVALU":"mg/L","BASE2":7.65111,"BASE":8.60496,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.46529,"PCHG2":6.08139,"CHG":-0.48856,"PCHG":-5.67764,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-07 12:02:21","ADY":537,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-310","SUBJID":"id-310","SITEID":"CHN-4","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.85139,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-20","TRTSDTM":"2019-07-20 12:02:21","TRTEDTM":"2022-07-20 06:02:21","TRT01SDTM":"2019-07-20 12:02:21","TRT01EDTM":"2021-07-20 00:02:21","TRT02SDTM":"2021-07-20 00:02:21","TRT02EDTM":"2022-07-20 06:02:21","AP01SDTM":"2019-07-20 12:02:21","AP01EDTM":"2021-07-20 00:02:21","AP02SDTM":"2021-07-20 00:02:21","AP02EDTM":"2022-07-20 06:02:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1233,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.64727,"AVALU":"mg/L","BASE2":7.65111,"BASE":8.60496,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.99616,"PCHG2":26.08981,"CHG":1.04231,"PCHG":12.11287,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-27 12:02:21","ADY":800,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-310","SUBJID":"id-310","SITEID":"CHN-4","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.85139,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-20","TRTSDTM":"2019-07-20 12:02:21","TRTEDTM":"2022-07-20 06:02:21","TRT01SDTM":"2019-07-20 12:02:21","TRT01EDTM":"2021-07-20 00:02:21","TRT02SDTM":"2021-07-20 00:02:21","TRT02EDTM":"2022-07-20 06:02:21","AP01SDTM":"2019-07-20 12:02:21","AP01EDTM":"2021-07-20 00:02:21","AP02SDTM":"2021-07-20 00:02:21","AP02EDTM":"2022-07-20 06:02:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6211,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.46661,"AVALU":"mg/L","BASE2":7.65111,"BASE":8.60496,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.8155,"PCHG2":23.72864,"CHG":0.86165,"PCHG":10.01344,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-07 12:02:21","ADY":933,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-310","SUBJID":"id-310","SITEID":"CHN-4","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.85139,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-20","TRTSDTM":"2019-07-20 12:02:21","TRTEDTM":"2022-07-20 06:02:21","TRT01SDTM":"2019-07-20 12:02:21","TRT01EDTM":"2021-07-20 00:02:21","TRT02SDTM":"2021-07-20 00:02:21","TRT02EDTM":"2022-07-20 06:02:21","AP01SDTM":"2019-07-20 12:02:21","AP01EDTM":"2021-07-20 00:02:21","AP02SDTM":"2021-07-20 00:02:21","AP02EDTM":"2022-07-20 06:02:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1211,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.72456,"AVALU":"mg/L","BASE2":7.65111,"BASE":8.60496,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.07345,"PCHG2":40.17006,"CHG":2.1196,"PCHG":24.63234,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-03-05 12:02:21","ADY":959,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-310","SUBJID":"id-310","SITEID":"CHN-4","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.85139,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-20","TRTSDTM":"2019-07-20 12:02:21","TRTEDTM":"2022-07-20 06:02:21","TRT01SDTM":"2019-07-20 12:02:21","TRT01EDTM":"2021-07-20 00:02:21","TRT02SDTM":"2021-07-20 00:02:21","TRT02EDTM":"2022-07-20 06:02:21","AP01SDTM":"2019-07-20 12:02:21","AP01EDTM":"2021-07-20 00:02:21","AP02SDTM":"2021-07-20 00:02:21","AP02EDTM":"2022-07-20 06:02:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6483,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98262,"AVALU":"g/L","BASE2":2.98262,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-01 12:02:21","ADY":286,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-310","SUBJID":"id-310","SITEID":"CHN-4","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.85139,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-20","TRTSDTM":"2019-07-20 12:02:21","TRTEDTM":"2022-07-20 06:02:21","TRT01SDTM":"2019-07-20 12:02:21","TRT01EDTM":"2021-07-20 00:02:21","TRT02SDTM":"2021-07-20 00:02:21","TRT02EDTM":"2022-07-20 06:02:21","AP01SDTM":"2019-07-20 12:02:21","AP01EDTM":"2021-07-20 00:02:21","AP02SDTM":"2021-07-20 00:02:21","AP02EDTM":"2022-07-20 06:02:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5492,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90395,"AVALU":"g/L","BASE2":2.98262,"BASE":2.90395,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.07867,"PCHG2":-2.63762,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-18 12:02:21","ADY":395,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-310","SUBJID":"id-310","SITEID":"CHN-4","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.85139,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-20","TRTSDTM":"2019-07-20 12:02:21","TRTEDTM":"2022-07-20 06:02:21","TRT01SDTM":"2019-07-20 12:02:21","TRT01EDTM":"2021-07-20 00:02:21","TRT02SDTM":"2021-07-20 00:02:21","TRT02EDTM":"2022-07-20 06:02:21","AP01SDTM":"2019-07-20 12:02:21","AP01EDTM":"2021-07-20 00:02:21","AP02SDTM":"2021-07-20 00:02:21","AP02EDTM":"2022-07-20 06:02:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5336,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86129,"AVALU":"g/L","BASE2":2.98262,"BASE":2.90395,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12133,"PCHG2":-4.068,"CHG":-0.04266,"PCHG":-1.46914,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-08 12:02:21","ADY":507,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-310","SUBJID":"id-310","SITEID":"CHN-4","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.85139,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-20","TRTSDTM":"2019-07-20 12:02:21","TRTEDTM":"2022-07-20 06:02:21","TRT01SDTM":"2019-07-20 12:02:21","TRT01EDTM":"2021-07-20 00:02:21","TRT02SDTM":"2021-07-20 00:02:21","TRT02EDTM":"2022-07-20 06:02:21","AP01SDTM":"2019-07-20 12:02:21","AP01EDTM":"2021-07-20 00:02:21","AP02SDTM":"2021-07-20 00:02:21","AP02EDTM":"2022-07-20 06:02:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2051,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.72131,"AVALU":"g/L","BASE2":2.98262,"BASE":2.90395,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.26131,"PCHG2":-8.76102,"CHG":-0.18264,"PCHG":-6.28928,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-07 12:02:21","ADY":537,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-310","SUBJID":"id-310","SITEID":"CHN-4","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.85139,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-20","TRTSDTM":"2019-07-20 12:02:21","TRTEDTM":"2022-07-20 06:02:21","TRT01SDTM":"2019-07-20 12:02:21","TRT01EDTM":"2021-07-20 00:02:21","TRT02SDTM":"2021-07-20 00:02:21","TRT02EDTM":"2022-07-20 06:02:21","AP01SDTM":"2019-07-20 12:02:21","AP01EDTM":"2021-07-20 00:02:21","AP02SDTM":"2021-07-20 00:02:21","AP02EDTM":"2022-07-20 06:02:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1111,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96526,"AVALU":"g/L","BASE2":2.98262,"BASE":2.90395,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01736,"PCHG2":-0.58199,"CHG":0.06131,"PCHG":2.11132,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-27 12:02:21","ADY":800,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-310","SUBJID":"id-310","SITEID":"CHN-4","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.85139,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-20","TRTSDTM":"2019-07-20 12:02:21","TRTEDTM":"2022-07-20 06:02:21","TRT01SDTM":"2019-07-20 12:02:21","TRT01EDTM":"2021-07-20 00:02:21","TRT02SDTM":"2021-07-20 00:02:21","TRT02EDTM":"2022-07-20 06:02:21","AP01SDTM":"2019-07-20 12:02:21","AP01EDTM":"2021-07-20 00:02:21","AP02SDTM":"2021-07-20 00:02:21","AP02EDTM":"2022-07-20 06:02:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6208,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84347,"AVALU":"g/L","BASE2":2.98262,"BASE":2.90395,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13915,"PCHG2":-4.66549,"CHG":-0.06048,"PCHG":-2.08281,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-07 12:02:21","ADY":933,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-310","SUBJID":"id-310","SITEID":"CHN-4","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.85139,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-20","TRTSDTM":"2019-07-20 12:02:21","TRTEDTM":"2022-07-20 06:02:21","TRT01SDTM":"2019-07-20 12:02:21","TRT01EDTM":"2021-07-20 00:02:21","TRT02SDTM":"2021-07-20 00:02:21","TRT02EDTM":"2022-07-20 06:02:21","AP01SDTM":"2019-07-20 12:02:21","AP01EDTM":"2021-07-20 00:02:21","AP02SDTM":"2021-07-20 00:02:21","AP02EDTM":"2022-07-20 06:02:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-08","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4697,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85857,"AVALU":"g/L","BASE2":2.98262,"BASE":2.90395,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12405,"PCHG2":-4.15904,"CHG":-0.04538,"PCHG":-1.56263,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-05 12:02:21","ADY":959,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-311","SUBJID":"id-311","SITEID":"CHN-4","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30046,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-10 04:39:48","TRTEDTM":"2023-08-10 22:39:48","TRT01SDTM":"2020-08-10 04:39:48","TRT01EDTM":"2022-08-10 16:39:48","TRT02SDTM":"2022-08-10 16:39:48","TRT02EDTM":"2023-08-10 22:39:48","AP01SDTM":"2020-08-10 04:39:48","AP01EDTM":"2022-08-10 16:39:48","AP02SDTM":"2022-08-10 16:39:48","AP02EDTM":"2023-08-10 22:39:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-10","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8187,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.34448,"AVALU":"U/L","BASE2":19.34448,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-19 04:39:48","ADY":101,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-311","SUBJID":"id-311","SITEID":"CHN-4","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30046,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-10 04:39:48","TRTEDTM":"2023-08-10 22:39:48","TRT01SDTM":"2020-08-10 04:39:48","TRT01EDTM":"2022-08-10 16:39:48","TRT02SDTM":"2022-08-10 16:39:48","TRT02EDTM":"2023-08-10 22:39:48","AP01SDTM":"2020-08-10 04:39:48","AP01EDTM":"2022-08-10 16:39:48","AP02SDTM":"2022-08-10 16:39:48","AP02EDTM":"2023-08-10 22:39:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-10","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1096,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.14406,"AVALU":"U/L","BASE2":19.34448,"BASE":19.14406,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.20042,"PCHG2":-1.03606,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-10 04:39:48","ADY":153,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-311","SUBJID":"id-311","SITEID":"CHN-4","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30046,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-10 04:39:48","TRTEDTM":"2023-08-10 22:39:48","TRT01SDTM":"2020-08-10 04:39:48","TRT01EDTM":"2022-08-10 16:39:48","TRT02SDTM":"2022-08-10 16:39:48","TRT02EDTM":"2023-08-10 22:39:48","AP01SDTM":"2020-08-10 04:39:48","AP01EDTM":"2022-08-10 16:39:48","AP02SDTM":"2022-08-10 16:39:48","AP02EDTM":"2023-08-10 22:39:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-10","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2590,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.98265,"AVALU":"U/L","BASE2":19.34448,"BASE":19.14406,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.36182,"PCHG2":-22.54816,"CHG":-4.1614,"PCHG":-21.73731,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-15 04:39:48","ADY":158,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-311","SUBJID":"id-311","SITEID":"CHN-4","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30046,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-10 04:39:48","TRTEDTM":"2023-08-10 22:39:48","TRT01SDTM":"2020-08-10 04:39:48","TRT01EDTM":"2022-08-10 16:39:48","TRT02SDTM":"2022-08-10 16:39:48","TRT02EDTM":"2023-08-10 22:39:48","AP01SDTM":"2020-08-10 04:39:48","AP01EDTM":"2022-08-10 16:39:48","AP02SDTM":"2022-08-10 16:39:48","AP02EDTM":"2023-08-10 22:39:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-10","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":97,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.14448,"AVALU":"U/L","BASE2":19.34448,"BASE":19.14406,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.80001,"PCHG2":76.50767,"CHG":15.00043,"PCHG":78.35554,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-28 04:39:48","ADY":202,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-311","SUBJID":"id-311","SITEID":"CHN-4","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30046,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-10 04:39:48","TRTEDTM":"2023-08-10 22:39:48","TRT01SDTM":"2020-08-10 04:39:48","TRT01EDTM":"2022-08-10 16:39:48","TRT02SDTM":"2022-08-10 16:39:48","TRT02EDTM":"2023-08-10 22:39:48","AP01SDTM":"2020-08-10 04:39:48","AP01EDTM":"2022-08-10 16:39:48","AP02SDTM":"2022-08-10 16:39:48","AP02EDTM":"2023-08-10 22:39:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-10","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7827,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.07438,"AVALU":"U/L","BASE2":19.34448,"BASE":19.14406,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.7299,"PCHG2":14.11205,"CHG":2.93032,"PCHG":15.3067,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-31 04:39:48","ADY":873,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-311","SUBJID":"id-311","SITEID":"CHN-4","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30046,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-10 04:39:48","TRTEDTM":"2023-08-10 22:39:48","TRT01SDTM":"2020-08-10 04:39:48","TRT01EDTM":"2022-08-10 16:39:48","TRT02SDTM":"2022-08-10 16:39:48","TRT02EDTM":"2023-08-10 22:39:48","AP01SDTM":"2020-08-10 04:39:48","AP01EDTM":"2022-08-10 16:39:48","AP02SDTM":"2022-08-10 16:39:48","AP02EDTM":"2023-08-10 22:39:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-10","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":118,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.56356,"AVALU":"U/L","BASE2":19.34448,"BASE":19.14406,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.21908,"PCHG2":52.82687,"CHG":10.4195,"PCHG":54.42683,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-24 04:39:48","ADY":897,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-311","SUBJID":"id-311","SITEID":"CHN-4","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30046,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-10 04:39:48","TRTEDTM":"2023-08-10 22:39:48","TRT01SDTM":"2020-08-10 04:39:48","TRT01EDTM":"2022-08-10 16:39:48","TRT02SDTM":"2022-08-10 16:39:48","TRT02EDTM":"2023-08-10 22:39:48","AP01SDTM":"2020-08-10 04:39:48","AP01EDTM":"2022-08-10 16:39:48","AP02SDTM":"2022-08-10 16:39:48","AP02EDTM":"2023-08-10 22:39:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-10","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4706,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.83391,"AVALU":"U/L","BASE2":19.34448,"BASE":19.14406,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.51057,"PCHG2":-23.31709,"CHG":-4.31015,"PCHG":-22.51429,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-24 04:39:48","ADY":1017,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-311","SUBJID":"id-311","SITEID":"CHN-4","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30046,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-10 04:39:48","TRTEDTM":"2023-08-10 22:39:48","TRT01SDTM":"2020-08-10 04:39:48","TRT01EDTM":"2022-08-10 16:39:48","TRT02SDTM":"2022-08-10 16:39:48","TRT02EDTM":"2023-08-10 22:39:48","AP01SDTM":"2020-08-10 04:39:48","AP01EDTM":"2022-08-10 16:39:48","AP02SDTM":"2022-08-10 16:39:48","AP02EDTM":"2023-08-10 22:39:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-10","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2963,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.32532,"AVALU":"mg/L","BASE2":8.32532,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-11-19 04:39:48","ADY":101,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-311","SUBJID":"id-311","SITEID":"CHN-4","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30046,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-10 04:39:48","TRTEDTM":"2023-08-10 22:39:48","TRT01SDTM":"2020-08-10 04:39:48","TRT01EDTM":"2022-08-10 16:39:48","TRT02SDTM":"2022-08-10 16:39:48","TRT02EDTM":"2023-08-10 22:39:48","AP01SDTM":"2020-08-10 04:39:48","AP01EDTM":"2022-08-10 16:39:48","AP02SDTM":"2022-08-10 16:39:48","AP02EDTM":"2023-08-10 22:39:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-10","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7378,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.24089,"AVALU":"mg/L","BASE2":8.32532,"BASE":10.24089,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.91557,"PCHG2":23.00894,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2021-01-10 04:39:48","ADY":153,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-311","SUBJID":"id-311","SITEID":"CHN-4","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30046,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-10 04:39:48","TRTEDTM":"2023-08-10 22:39:48","TRT01SDTM":"2020-08-10 04:39:48","TRT01EDTM":"2022-08-10 16:39:48","TRT02SDTM":"2022-08-10 16:39:48","TRT02EDTM":"2023-08-10 22:39:48","AP01SDTM":"2020-08-10 04:39:48","AP01EDTM":"2022-08-10 16:39:48","AP02SDTM":"2022-08-10 16:39:48","AP02EDTM":"2023-08-10 22:39:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-10","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7512,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.52595,"AVALU":"mg/L","BASE2":8.32532,"BASE":10.24089,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.20063,"PCHG2":26.43293,"CHG":0.28506,"PCHG":2.78353,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"1","ADTM":"2021-01-15 04:39:48","ADY":158,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-311","SUBJID":"id-311","SITEID":"CHN-4","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30046,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-10 04:39:48","TRTEDTM":"2023-08-10 22:39:48","TRT01SDTM":"2020-08-10 04:39:48","TRT01EDTM":"2022-08-10 16:39:48","TRT02SDTM":"2022-08-10 16:39:48","TRT02EDTM":"2023-08-10 22:39:48","AP01SDTM":"2020-08-10 04:39:48","AP01EDTM":"2022-08-10 16:39:48","AP02SDTM":"2022-08-10 16:39:48","AP02EDTM":"2023-08-10 22:39:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-10","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4309,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.82467,"AVALU":"mg/L","BASE2":8.32532,"BASE":10.24089,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.50066,"PCHG2":-6.01367,"CHG":-2.41623,"PCHG":-23.5939,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-3","BTOXGR":"1","ADTM":"2021-02-28 04:39:48","ADY":202,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-311","SUBJID":"id-311","SITEID":"CHN-4","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30046,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-10 04:39:48","TRTEDTM":"2023-08-10 22:39:48","TRT01SDTM":"2020-08-10 04:39:48","TRT01EDTM":"2022-08-10 16:39:48","TRT02SDTM":"2022-08-10 16:39:48","TRT02EDTM":"2023-08-10 22:39:48","AP01SDTM":"2020-08-10 04:39:48","AP01EDTM":"2022-08-10 16:39:48","AP02SDTM":"2022-08-10 16:39:48","AP02EDTM":"2023-08-10 22:39:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-10","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8031,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.47972,"AVALU":"mg/L","BASE2":8.32532,"BASE":10.24089,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.8456,"PCHG2":-22.16851,"CHG":-3.76117,"PCHG":-36.72697,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-4","BTOXGR":"1","ADTM":"2022-12-31 04:39:48","ADY":873,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-311","SUBJID":"id-311","SITEID":"CHN-4","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30046,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-10 04:39:48","TRTEDTM":"2023-08-10 22:39:48","TRT01SDTM":"2020-08-10 04:39:48","TRT01EDTM":"2022-08-10 16:39:48","TRT02SDTM":"2022-08-10 16:39:48","TRT02EDTM":"2023-08-10 22:39:48","AP01SDTM":"2020-08-10 04:39:48","AP01EDTM":"2022-08-10 16:39:48","AP02SDTM":"2022-08-10 16:39:48","AP02EDTM":"2023-08-10 22:39:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-10","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6010,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.52645,"AVALU":"mg/L","BASE2":8.32532,"BASE":10.24089,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.20113,"PCHG2":14.4274,"CHG":-0.71444,"PCHG":-6.97636,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2023-01-24 04:39:48","ADY":897,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-311","SUBJID":"id-311","SITEID":"CHN-4","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30046,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-10 04:39:48","TRTEDTM":"2023-08-10 22:39:48","TRT01SDTM":"2020-08-10 04:39:48","TRT01EDTM":"2022-08-10 16:39:48","TRT02SDTM":"2022-08-10 16:39:48","TRT02EDTM":"2023-08-10 22:39:48","AP01SDTM":"2020-08-10 04:39:48","AP01EDTM":"2022-08-10 16:39:48","AP02SDTM":"2022-08-10 16:39:48","AP02EDTM":"2023-08-10 22:39:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-10","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6140,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.37817,"AVALU":"mg/L","BASE2":8.32532,"BASE":10.24089,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.05284,"PCHG2":12.64624,"CHG":-0.86273,"PCHG":-8.42435,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2023-05-24 04:39:48","ADY":1017,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-311","SUBJID":"id-311","SITEID":"CHN-4","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30046,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-10 04:39:48","TRTEDTM":"2023-08-10 22:39:48","TRT01SDTM":"2020-08-10 04:39:48","TRT01EDTM":"2022-08-10 16:39:48","TRT02SDTM":"2022-08-10 16:39:48","TRT02EDTM":"2023-08-10 22:39:48","AP01SDTM":"2020-08-10 04:39:48","AP01EDTM":"2022-08-10 16:39:48","AP02SDTM":"2022-08-10 16:39:48","AP02EDTM":"2023-08-10 22:39:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-10","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5217,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79677,"AVALU":"g/L","BASE2":2.79677,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-19 04:39:48","ADY":101,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-311","SUBJID":"id-311","SITEID":"CHN-4","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30046,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-10 04:39:48","TRTEDTM":"2023-08-10 22:39:48","TRT01SDTM":"2020-08-10 04:39:48","TRT01EDTM":"2022-08-10 16:39:48","TRT02SDTM":"2022-08-10 16:39:48","TRT02EDTM":"2023-08-10 22:39:48","AP01SDTM":"2020-08-10 04:39:48","AP01EDTM":"2022-08-10 16:39:48","AP02SDTM":"2022-08-10 16:39:48","AP02EDTM":"2023-08-10 22:39:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-10","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5730,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7867,"AVALU":"g/L","BASE2":2.79677,"BASE":2.7867,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.01007,"PCHG2":-0.36008,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-10 04:39:48","ADY":153,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-311","SUBJID":"id-311","SITEID":"CHN-4","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30046,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-10 04:39:48","TRTEDTM":"2023-08-10 22:39:48","TRT01SDTM":"2020-08-10 04:39:48","TRT01EDTM":"2022-08-10 16:39:48","TRT02SDTM":"2022-08-10 16:39:48","TRT02EDTM":"2023-08-10 22:39:48","AP01SDTM":"2020-08-10 04:39:48","AP01EDTM":"2022-08-10 16:39:48","AP02SDTM":"2022-08-10 16:39:48","AP02EDTM":"2023-08-10 22:39:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-10","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2471,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.06484,"AVALU":"g/L","BASE2":2.79677,"BASE":2.7867,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.26807,"PCHG2":9.58502,"CHG":0.27814,"PCHG":9.98104,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-01-15 04:39:48","ADY":158,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-311","SUBJID":"id-311","SITEID":"CHN-4","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30046,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-10 04:39:48","TRTEDTM":"2023-08-10 22:39:48","TRT01SDTM":"2020-08-10 04:39:48","TRT01EDTM":"2022-08-10 16:39:48","TRT02SDTM":"2022-08-10 16:39:48","TRT02EDTM":"2023-08-10 22:39:48","AP01SDTM":"2020-08-10 04:39:48","AP01EDTM":"2022-08-10 16:39:48","AP02SDTM":"2022-08-10 16:39:48","AP02EDTM":"2023-08-10 22:39:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-10","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2205,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83656,"AVALU":"g/L","BASE2":2.79677,"BASE":2.7867,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03979,"PCHG2":1.42259,"CHG":0.04986,"PCHG":1.78911,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-28 04:39:48","ADY":202,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-311","SUBJID":"id-311","SITEID":"CHN-4","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30046,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-10 04:39:48","TRTEDTM":"2023-08-10 22:39:48","TRT01SDTM":"2020-08-10 04:39:48","TRT01EDTM":"2022-08-10 16:39:48","TRT02SDTM":"2022-08-10 16:39:48","TRT02EDTM":"2023-08-10 22:39:48","AP01SDTM":"2020-08-10 04:39:48","AP01EDTM":"2022-08-10 16:39:48","AP02SDTM":"2022-08-10 16:39:48","AP02EDTM":"2023-08-10 22:39:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-10","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6465,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82925,"AVALU":"g/L","BASE2":2.79677,"BASE":2.7867,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03248,"PCHG2":1.16148,"CHG":0.04255,"PCHG":1.52706,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-31 04:39:48","ADY":873,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-311","SUBJID":"id-311","SITEID":"CHN-4","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30046,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-10 04:39:48","TRTEDTM":"2023-08-10 22:39:48","TRT01SDTM":"2020-08-10 04:39:48","TRT01EDTM":"2022-08-10 16:39:48","TRT02SDTM":"2022-08-10 16:39:48","TRT02EDTM":"2023-08-10 22:39:48","AP01SDTM":"2020-08-10 04:39:48","AP01EDTM":"2022-08-10 16:39:48","AP02SDTM":"2022-08-10 16:39:48","AP02EDTM":"2023-08-10 22:39:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-10","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3533,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98212,"AVALU":"g/L","BASE2":2.79677,"BASE":2.7867,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18535,"PCHG2":6.62734,"CHG":0.19542,"PCHG":7.01266,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-24 04:39:48","ADY":897,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-311","SUBJID":"id-311","SITEID":"CHN-4","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.30046,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-06","TRTSDTM":"2020-08-10 04:39:48","TRTEDTM":"2023-08-10 22:39:48","TRT01SDTM":"2020-08-10 04:39:48","TRT01EDTM":"2022-08-10 16:39:48","TRT02SDTM":"2022-08-10 16:39:48","TRT02EDTM":"2023-08-10 22:39:48","AP01SDTM":"2020-08-10 04:39:48","AP01EDTM":"2022-08-10 16:39:48","AP02SDTM":"2022-08-10 16:39:48","AP02EDTM":"2023-08-10 22:39:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-10","EOSDY":1096,"LSTALVDT":"2023-08-29","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2255,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82562,"AVALU":"g/L","BASE2":2.79677,"BASE":2.7867,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02884,"PCHG2":1.03134,"CHG":0.03891,"PCHG":1.39644,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-24 04:39:48","ADY":1017,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-335","SUBJID":"id-335","SITEID":"CHN-4","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.57019,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-13","TRTSDTM":"2020-04-17 12:58:47","TRTEDTM":"2023-04-18 06:58:47","TRT01SDTM":"2020-04-17 12:58:47","TRT01EDTM":"2022-04-18 00:58:47","TRT02SDTM":"2022-04-18 00:58:47","TRT02EDTM":"2023-04-18 06:58:47","AP01SDTM":"2020-04-17 12:58:47","AP01EDTM":"2022-04-18 00:58:47","AP02SDTM":"2022-04-18 00:58:47","AP02EDTM":"2023-04-18 06:58:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-18","EOSDY":1096,"LSTALVDT":"2023-05-11","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4730,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.34108,"AVALU":"U/L","BASE2":28.34108,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-03 12:58:47","ADY":230,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-335","SUBJID":"id-335","SITEID":"CHN-4","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.57019,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-13","TRTSDTM":"2020-04-17 12:58:47","TRTEDTM":"2023-04-18 06:58:47","TRT01SDTM":"2020-04-17 12:58:47","TRT01EDTM":"2022-04-18 00:58:47","TRT02SDTM":"2022-04-18 00:58:47","TRT02EDTM":"2023-04-18 06:58:47","AP01SDTM":"2020-04-17 12:58:47","AP01EDTM":"2022-04-18 00:58:47","AP02SDTM":"2022-04-18 00:58:47","AP02EDTM":"2023-04-18 06:58:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-18","EOSDY":1096,"LSTALVDT":"2023-05-11","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6800,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.5322,"AVALU":"U/L","BASE2":28.34108,"BASE":14.5322,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-13.80888,"PCHG2":-48.72389,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-23 12:58:47","ADY":371,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-335","SUBJID":"id-335","SITEID":"CHN-4","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.57019,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-13","TRTSDTM":"2020-04-17 12:58:47","TRTEDTM":"2023-04-18 06:58:47","TRT01SDTM":"2020-04-17 12:58:47","TRT01EDTM":"2022-04-18 00:58:47","TRT02SDTM":"2022-04-18 00:58:47","TRT02EDTM":"2023-04-18 06:58:47","AP01SDTM":"2020-04-17 12:58:47","AP01EDTM":"2022-04-18 00:58:47","AP02SDTM":"2022-04-18 00:58:47","AP02EDTM":"2023-04-18 06:58:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-18","EOSDY":1096,"LSTALVDT":"2023-05-11","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3216,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.71045,"AVALU":"U/L","BASE2":28.34108,"BASE":14.5322,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.36938,"PCHG2":22.47401,"CHG":20.17825,"PCHG":138.85201,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-07 12:58:47","ADY":720,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-335","SUBJID":"id-335","SITEID":"CHN-4","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.57019,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-13","TRTSDTM":"2020-04-17 12:58:47","TRTEDTM":"2023-04-18 06:58:47","TRT01SDTM":"2020-04-17 12:58:47","TRT01EDTM":"2022-04-18 00:58:47","TRT02SDTM":"2022-04-18 00:58:47","TRT02EDTM":"2023-04-18 06:58:47","AP01SDTM":"2020-04-17 12:58:47","AP01EDTM":"2022-04-18 00:58:47","AP02SDTM":"2022-04-18 00:58:47","AP02EDTM":"2023-04-18 06:58:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-18","EOSDY":1096,"LSTALVDT":"2023-05-11","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3622,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.14281,"AVALU":"U/L","BASE2":28.34108,"BASE":14.5322,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.19827,"PCHG2":-25.39872,"CHG":6.61061,"PCHG":45.48937,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-14 12:58:47","ADY":727,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-335","SUBJID":"id-335","SITEID":"CHN-4","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.57019,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-13","TRTSDTM":"2020-04-17 12:58:47","TRTEDTM":"2023-04-18 06:58:47","TRT01SDTM":"2020-04-17 12:58:47","TRT01EDTM":"2022-04-18 00:58:47","TRT02SDTM":"2022-04-18 00:58:47","TRT02EDTM":"2023-04-18 06:58:47","AP01SDTM":"2020-04-17 12:58:47","AP01EDTM":"2022-04-18 00:58:47","AP02SDTM":"2022-04-18 00:58:47","AP02EDTM":"2023-04-18 06:58:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-18","EOSDY":1096,"LSTALVDT":"2023-05-11","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3602,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.10566,"AVALU":"U/L","BASE2":28.34108,"BASE":14.5322,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.23542,"PCHG2":-7.88757,"CHG":11.57345,"PCHG":79.64007,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-16 12:58:47","ADY":729,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-335","SUBJID":"id-335","SITEID":"CHN-4","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.57019,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-13","TRTSDTM":"2020-04-17 12:58:47","TRTEDTM":"2023-04-18 06:58:47","TRT01SDTM":"2020-04-17 12:58:47","TRT01EDTM":"2022-04-18 00:58:47","TRT02SDTM":"2022-04-18 00:58:47","TRT02EDTM":"2023-04-18 06:58:47","AP01SDTM":"2020-04-17 12:58:47","AP01EDTM":"2022-04-18 00:58:47","AP02SDTM":"2022-04-18 00:58:47","AP02EDTM":"2023-04-18 06:58:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-18","EOSDY":1096,"LSTALVDT":"2023-05-11","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7861,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.0355,"AVALU":"U/L","BASE2":28.34108,"BASE":14.5322,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.30558,"PCHG2":-39.89114,"CHG":2.5033,"PCHG":17.22586,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-26 12:58:47","ADY":769,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-335","SUBJID":"id-335","SITEID":"CHN-4","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.57019,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-13","TRTSDTM":"2020-04-17 12:58:47","TRTEDTM":"2023-04-18 06:58:47","TRT01SDTM":"2020-04-17 12:58:47","TRT01EDTM":"2022-04-18 00:58:47","TRT02SDTM":"2022-04-18 00:58:47","TRT02EDTM":"2023-04-18 06:58:47","AP01SDTM":"2020-04-17 12:58:47","AP01EDTM":"2022-04-18 00:58:47","AP02SDTM":"2022-04-18 00:58:47","AP02EDTM":"2023-04-18 06:58:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-18","EOSDY":1096,"LSTALVDT":"2023-05-11","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3476,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.68779,"AVALU":"U/L","BASE2":28.34108,"BASE":14.5322,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.65329,"PCHG2":-9.36199,"CHG":11.15559,"PCHG":76.76461,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-23 12:58:47","ADY":950,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-335","SUBJID":"id-335","SITEID":"CHN-4","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.57019,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-13","TRTSDTM":"2020-04-17 12:58:47","TRTEDTM":"2023-04-18 06:58:47","TRT01SDTM":"2020-04-17 12:58:47","TRT01EDTM":"2022-04-18 00:58:47","TRT02SDTM":"2022-04-18 00:58:47","TRT02EDTM":"2023-04-18 06:58:47","AP01SDTM":"2020-04-17 12:58:47","AP01EDTM":"2022-04-18 00:58:47","AP02SDTM":"2022-04-18 00:58:47","AP02EDTM":"2023-04-18 06:58:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-18","EOSDY":1096,"LSTALVDT":"2023-05-11","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2850,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.40237,"AVALU":"mg/L","BASE2":9.40237,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-03 12:58:47","ADY":230,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-335","SUBJID":"id-335","SITEID":"CHN-4","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.57019,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-13","TRTSDTM":"2020-04-17 12:58:47","TRTEDTM":"2023-04-18 06:58:47","TRT01SDTM":"2020-04-17 12:58:47","TRT01EDTM":"2022-04-18 00:58:47","TRT02SDTM":"2022-04-18 00:58:47","TRT02EDTM":"2023-04-18 06:58:47","AP01SDTM":"2020-04-17 12:58:47","AP01EDTM":"2022-04-18 00:58:47","AP02SDTM":"2022-04-18 00:58:47","AP02EDTM":"2023-04-18 06:58:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-18","EOSDY":1096,"LSTALVDT":"2023-05-11","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1355,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.4146,"AVALU":"mg/L","BASE2":9.40237,"BASE":9.4146,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.01223,"PCHG2":0.13004,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-23 12:58:47","ADY":371,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-335","SUBJID":"id-335","SITEID":"CHN-4","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.57019,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-13","TRTSDTM":"2020-04-17 12:58:47","TRTEDTM":"2023-04-18 06:58:47","TRT01SDTM":"2020-04-17 12:58:47","TRT01EDTM":"2022-04-18 00:58:47","TRT02SDTM":"2022-04-18 00:58:47","TRT02EDTM":"2023-04-18 06:58:47","AP01SDTM":"2020-04-17 12:58:47","AP01EDTM":"2022-04-18 00:58:47","AP02SDTM":"2022-04-18 00:58:47","AP02EDTM":"2023-04-18 06:58:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-18","EOSDY":1096,"LSTALVDT":"2023-05-11","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":916,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.81205,"AVALU":"mg/L","BASE2":9.40237,"BASE":9.4146,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.59032,"PCHG2":-6.27845,"CHG":-0.60255,"PCHG":-6.40017,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-07 12:58:47","ADY":720,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-335","SUBJID":"id-335","SITEID":"CHN-4","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.57019,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-13","TRTSDTM":"2020-04-17 12:58:47","TRTEDTM":"2023-04-18 06:58:47","TRT01SDTM":"2020-04-17 12:58:47","TRT01EDTM":"2022-04-18 00:58:47","TRT02SDTM":"2022-04-18 00:58:47","TRT02EDTM":"2023-04-18 06:58:47","AP01SDTM":"2020-04-17 12:58:47","AP01EDTM":"2022-04-18 00:58:47","AP02SDTM":"2022-04-18 00:58:47","AP02EDTM":"2023-04-18 06:58:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-18","EOSDY":1096,"LSTALVDT":"2023-05-11","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8047,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.24012,"AVALU":"mg/L","BASE2":9.40237,"BASE":9.4146,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.83774,"PCHG2":8.90991,"CHG":0.82552,"PCHG":8.76847,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-04-14 12:58:47","ADY":727,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-335","SUBJID":"id-335","SITEID":"CHN-4","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.57019,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-13","TRTSDTM":"2020-04-17 12:58:47","TRTEDTM":"2023-04-18 06:58:47","TRT01SDTM":"2020-04-17 12:58:47","TRT01EDTM":"2022-04-18 00:58:47","TRT02SDTM":"2022-04-18 00:58:47","TRT02EDTM":"2023-04-18 06:58:47","AP01SDTM":"2020-04-17 12:58:47","AP01EDTM":"2022-04-18 00:58:47","AP02SDTM":"2022-04-18 00:58:47","AP02EDTM":"2023-04-18 06:58:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-18","EOSDY":1096,"LSTALVDT":"2023-05-11","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6345,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.19542,"AVALU":"mg/L","BASE2":9.40237,"BASE":9.4146,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20695,"PCHG2":-2.20108,"CHG":-0.21918,"PCHG":-2.3281,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-16 12:58:47","ADY":729,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-335","SUBJID":"id-335","SITEID":"CHN-4","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.57019,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-13","TRTSDTM":"2020-04-17 12:58:47","TRTEDTM":"2023-04-18 06:58:47","TRT01SDTM":"2020-04-17 12:58:47","TRT01EDTM":"2022-04-18 00:58:47","TRT02SDTM":"2022-04-18 00:58:47","TRT02EDTM":"2023-04-18 06:58:47","AP01SDTM":"2020-04-17 12:58:47","AP01EDTM":"2022-04-18 00:58:47","AP02SDTM":"2022-04-18 00:58:47","AP02EDTM":"2023-04-18 06:58:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-18","EOSDY":1096,"LSTALVDT":"2023-05-11","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1551,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.37941,"AVALU":"mg/L","BASE2":9.40237,"BASE":9.4146,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.02296,"PCHG2":-10.87982,"CHG":-1.03519,"PCHG":-10.99556,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-26 12:58:47","ADY":769,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-335","SUBJID":"id-335","SITEID":"CHN-4","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.57019,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-13","TRTSDTM":"2020-04-17 12:58:47","TRTEDTM":"2023-04-18 06:58:47","TRT01SDTM":"2020-04-17 12:58:47","TRT01EDTM":"2022-04-18 00:58:47","TRT02SDTM":"2022-04-18 00:58:47","TRT02EDTM":"2023-04-18 06:58:47","AP01SDTM":"2020-04-17 12:58:47","AP01EDTM":"2022-04-18 00:58:47","AP02SDTM":"2022-04-18 00:58:47","AP02EDTM":"2023-04-18 06:58:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-18","EOSDY":1096,"LSTALVDT":"2023-05-11","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4536,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.84764,"AVALU":"mg/L","BASE2":9.40237,"BASE":9.4146,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.44527,"PCHG2":4.73568,"CHG":0.43304,"PCHG":4.59966,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-23 12:58:47","ADY":950,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-335","SUBJID":"id-335","SITEID":"CHN-4","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.57019,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-13","TRTSDTM":"2020-04-17 12:58:47","TRTEDTM":"2023-04-18 06:58:47","TRT01SDTM":"2020-04-17 12:58:47","TRT01EDTM":"2022-04-18 00:58:47","TRT02SDTM":"2022-04-18 00:58:47","TRT02EDTM":"2023-04-18 06:58:47","AP01SDTM":"2020-04-17 12:58:47","AP01EDTM":"2022-04-18 00:58:47","AP02SDTM":"2022-04-18 00:58:47","AP02EDTM":"2023-04-18 06:58:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-18","EOSDY":1096,"LSTALVDT":"2023-05-11","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2964,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88968,"AVALU":"g/L","BASE2":2.88968,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-03 12:58:47","ADY":230,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-335","SUBJID":"id-335","SITEID":"CHN-4","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.57019,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-13","TRTSDTM":"2020-04-17 12:58:47","TRTEDTM":"2023-04-18 06:58:47","TRT01SDTM":"2020-04-17 12:58:47","TRT01EDTM":"2022-04-18 00:58:47","TRT02SDTM":"2022-04-18 00:58:47","TRT02EDTM":"2023-04-18 06:58:47","AP01SDTM":"2020-04-17 12:58:47","AP01EDTM":"2022-04-18 00:58:47","AP02SDTM":"2022-04-18 00:58:47","AP02EDTM":"2023-04-18 06:58:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-18","EOSDY":1096,"LSTALVDT":"2023-05-11","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6645,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74837,"AVALU":"g/L","BASE2":2.88968,"BASE":2.74837,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.14131,"PCHG2":-4.89006,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-23 12:58:47","ADY":371,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-335","SUBJID":"id-335","SITEID":"CHN-4","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.57019,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-13","TRTSDTM":"2020-04-17 12:58:47","TRTEDTM":"2023-04-18 06:58:47","TRT01SDTM":"2020-04-17 12:58:47","TRT01EDTM":"2022-04-18 00:58:47","TRT02SDTM":"2022-04-18 00:58:47","TRT02EDTM":"2023-04-18 06:58:47","AP01SDTM":"2020-04-17 12:58:47","AP01EDTM":"2022-04-18 00:58:47","AP02SDTM":"2022-04-18 00:58:47","AP02EDTM":"2023-04-18 06:58:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-18","EOSDY":1096,"LSTALVDT":"2023-05-11","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5191,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78964,"AVALU":"g/L","BASE2":2.88968,"BASE":2.74837,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10004,"PCHG2":-3.4619,"CHG":0.04127,"PCHG":1.50159,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-07 12:58:47","ADY":720,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-335","SUBJID":"id-335","SITEID":"CHN-4","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.57019,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-13","TRTSDTM":"2020-04-17 12:58:47","TRTEDTM":"2023-04-18 06:58:47","TRT01SDTM":"2020-04-17 12:58:47","TRT01EDTM":"2022-04-18 00:58:47","TRT02SDTM":"2022-04-18 00:58:47","TRT02EDTM":"2023-04-18 06:58:47","AP01SDTM":"2020-04-17 12:58:47","AP01EDTM":"2022-04-18 00:58:47","AP02SDTM":"2022-04-18 00:58:47","AP02EDTM":"2023-04-18 06:58:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-18","EOSDY":1096,"LSTALVDT":"2023-05-11","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5033,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85315,"AVALU":"g/L","BASE2":2.88968,"BASE":2.74837,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03653,"PCHG2":-1.26399,"CHG":0.10478,"PCHG":3.8125,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-14 12:58:47","ADY":727,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-335","SUBJID":"id-335","SITEID":"CHN-4","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.57019,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-13","TRTSDTM":"2020-04-17 12:58:47","TRTEDTM":"2023-04-18 06:58:47","TRT01SDTM":"2020-04-17 12:58:47","TRT01EDTM":"2022-04-18 00:58:47","TRT02SDTM":"2022-04-18 00:58:47","TRT02EDTM":"2023-04-18 06:58:47","AP01SDTM":"2020-04-17 12:58:47","AP01EDTM":"2022-04-18 00:58:47","AP02SDTM":"2022-04-18 00:58:47","AP02EDTM":"2023-04-18 06:58:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-18","EOSDY":1096,"LSTALVDT":"2023-05-11","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5491,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99244,"AVALU":"g/L","BASE2":2.88968,"BASE":2.74837,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10276,"PCHG2":3.55616,"CHG":0.24407,"PCHG":8.88048,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-16 12:58:47","ADY":729,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-335","SUBJID":"id-335","SITEID":"CHN-4","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.57019,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-13","TRTSDTM":"2020-04-17 12:58:47","TRTEDTM":"2023-04-18 06:58:47","TRT01SDTM":"2020-04-17 12:58:47","TRT01EDTM":"2022-04-18 00:58:47","TRT02SDTM":"2022-04-18 00:58:47","TRT02EDTM":"2023-04-18 06:58:47","AP01SDTM":"2020-04-17 12:58:47","AP01EDTM":"2022-04-18 00:58:47","AP02SDTM":"2022-04-18 00:58:47","AP02EDTM":"2023-04-18 06:58:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-18","EOSDY":1096,"LSTALVDT":"2023-05-11","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8392,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9625,"AVALU":"g/L","BASE2":2.88968,"BASE":2.74837,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07282,"PCHG2":2.52014,"CHG":0.21413,"PCHG":7.79119,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-26 12:58:47","ADY":769,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-335","SUBJID":"id-335","SITEID":"CHN-4","AGE":33,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":2.57019,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-13","TRTSDTM":"2020-04-17 12:58:47","TRTEDTM":"2023-04-18 06:58:47","TRT01SDTM":"2020-04-17 12:58:47","TRT01EDTM":"2022-04-18 00:58:47","TRT02SDTM":"2022-04-18 00:58:47","TRT02EDTM":"2023-04-18 06:58:47","AP01SDTM":"2020-04-17 12:58:47","AP01EDTM":"2022-04-18 00:58:47","AP02SDTM":"2022-04-18 00:58:47","AP02EDTM":"2023-04-18 06:58:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-18","EOSDY":1096,"LSTALVDT":"2023-05-11","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2278,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82379,"AVALU":"g/L","BASE2":2.88968,"BASE":2.74837,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06589,"PCHG2":-2.28016,"CHG":0.07542,"PCHG":2.74408,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-23 12:58:47","ADY":950,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-370","SUBJID":"id-370","SITEID":"CHN-4","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.09845,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-28","TRTSDTM":"2019-03-29 19:55:52","TRTEDTM":"2022-03-29 13:55:52","TRT01SDTM":"2019-03-29 19:55:52","TRT01EDTM":"2021-03-29 07:55:52","TRT02SDTM":"2021-03-29 07:55:52","TRT02EDTM":"2022-03-29 13:55:52","AP01SDTM":"2019-03-29 19:55:52","AP01EDTM":"2021-03-29 07:55:52","AP02SDTM":"2021-03-29 07:55:52","AP02EDTM":"2022-03-29 13:55:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-29","EOSDY":1096,"LSTALVDT":"2022-04-24","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3174,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.93901,"AVALU":"U/L","BASE2":23.93901,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-18 19:55:52","ADY":142,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-370","SUBJID":"id-370","SITEID":"CHN-4","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.09845,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-28","TRTSDTM":"2019-03-29 19:55:52","TRTEDTM":"2022-03-29 13:55:52","TRT01SDTM":"2019-03-29 19:55:52","TRT01EDTM":"2021-03-29 07:55:52","TRT02SDTM":"2021-03-29 07:55:52","TRT02EDTM":"2022-03-29 13:55:52","AP01SDTM":"2019-03-29 19:55:52","AP01EDTM":"2021-03-29 07:55:52","AP02SDTM":"2021-03-29 07:55:52","AP02EDTM":"2022-03-29 13:55:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-29","EOSDY":1096,"LSTALVDT":"2022-04-24","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4292,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.95726,"AVALU":"U/L","BASE2":23.93901,"BASE":20.95726,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.98176,"PCHG2":-12.45564,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-19 19:55:52","ADY":327,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-370","SUBJID":"id-370","SITEID":"CHN-4","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.09845,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-28","TRTSDTM":"2019-03-29 19:55:52","TRTEDTM":"2022-03-29 13:55:52","TRT01SDTM":"2019-03-29 19:55:52","TRT01EDTM":"2021-03-29 07:55:52","TRT02SDTM":"2021-03-29 07:55:52","TRT02EDTM":"2022-03-29 13:55:52","AP01SDTM":"2019-03-29 19:55:52","AP01EDTM":"2021-03-29 07:55:52","AP02SDTM":"2021-03-29 07:55:52","AP02EDTM":"2022-03-29 13:55:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-29","EOSDY":1096,"LSTALVDT":"2022-04-24","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":358,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.14661,"AVALU":"U/L","BASE2":23.93901,"BASE":20.95726,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.79241,"PCHG2":-70.14661,"CHG":-13.81065,"PCHG":-65.89912,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-06 19:55:52","ADY":830,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-370","SUBJID":"id-370","SITEID":"CHN-4","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.09845,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-28","TRTSDTM":"2019-03-29 19:55:52","TRTEDTM":"2022-03-29 13:55:52","TRT01SDTM":"2019-03-29 19:55:52","TRT01EDTM":"2021-03-29 07:55:52","TRT02SDTM":"2021-03-29 07:55:52","TRT02EDTM":"2022-03-29 13:55:52","AP01SDTM":"2019-03-29 19:55:52","AP01EDTM":"2021-03-29 07:55:52","AP02SDTM":"2021-03-29 07:55:52","AP02EDTM":"2022-03-29 13:55:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-29","EOSDY":1096,"LSTALVDT":"2022-04-24","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5487,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.00829,"AVALU":"U/L","BASE2":23.93901,"BASE":20.95726,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.93073,"PCHG2":-16.41975,"CHG":-0.94897,"PCHG":-4.52812,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-08 19:55:52","ADY":863,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-370","SUBJID":"id-370","SITEID":"CHN-4","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.09845,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-28","TRTSDTM":"2019-03-29 19:55:52","TRTEDTM":"2022-03-29 13:55:52","TRT01SDTM":"2019-03-29 19:55:52","TRT01EDTM":"2021-03-29 07:55:52","TRT02SDTM":"2021-03-29 07:55:52","TRT02EDTM":"2022-03-29 13:55:52","AP01SDTM":"2019-03-29 19:55:52","AP01EDTM":"2021-03-29 07:55:52","AP02SDTM":"2021-03-29 07:55:52","AP02EDTM":"2022-03-29 13:55:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-29","EOSDY":1096,"LSTALVDT":"2022-04-24","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6573,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.90869,"AVALU":"U/L","BASE2":23.93901,"BASE":20.95726,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-18.03033,"PCHG2":-75.31775,"CHG":-15.04857,"PCHG":-71.80601,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-08-20 19:55:52","ADY":875,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-370","SUBJID":"id-370","SITEID":"CHN-4","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.09845,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-28","TRTSDTM":"2019-03-29 19:55:52","TRTEDTM":"2022-03-29 13:55:52","TRT01SDTM":"2019-03-29 19:55:52","TRT01EDTM":"2021-03-29 07:55:52","TRT02SDTM":"2021-03-29 07:55:52","TRT02EDTM":"2022-03-29 13:55:52","AP01SDTM":"2019-03-29 19:55:52","AP01EDTM":"2021-03-29 07:55:52","AP02SDTM":"2021-03-29 07:55:52","AP02EDTM":"2022-03-29 13:55:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-29","EOSDY":1096,"LSTALVDT":"2022-04-24","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4249,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.13491,"AVALU":"U/L","BASE2":23.93901,"BASE":20.95726,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.1959,"PCHG2":17.52746,"CHG":7.17766,"PCHG":34.24903,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-06 19:55:52","ADY":922,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-370","SUBJID":"id-370","SITEID":"CHN-4","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.09845,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-28","TRTSDTM":"2019-03-29 19:55:52","TRTEDTM":"2022-03-29 13:55:52","TRT01SDTM":"2019-03-29 19:55:52","TRT01EDTM":"2021-03-29 07:55:52","TRT02SDTM":"2021-03-29 07:55:52","TRT02EDTM":"2022-03-29 13:55:52","AP01SDTM":"2019-03-29 19:55:52","AP01EDTM":"2021-03-29 07:55:52","AP02SDTM":"2021-03-29 07:55:52","AP02EDTM":"2022-03-29 13:55:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-29","EOSDY":1096,"LSTALVDT":"2022-04-24","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2530,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.83636,"AVALU":"U/L","BASE2":23.93901,"BASE":20.95726,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.10266,"PCHG2":-46.37893,"CHG":-8.1209,"PCHG":-38.74983,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-17 19:55:52","ADY":964,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-370","SUBJID":"id-370","SITEID":"CHN-4","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.09845,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-28","TRTSDTM":"2019-03-29 19:55:52","TRTEDTM":"2022-03-29 13:55:52","TRT01SDTM":"2019-03-29 19:55:52","TRT01EDTM":"2021-03-29 07:55:52","TRT02SDTM":"2021-03-29 07:55:52","TRT02EDTM":"2022-03-29 13:55:52","AP01SDTM":"2019-03-29 19:55:52","AP01EDTM":"2021-03-29 07:55:52","AP02SDTM":"2021-03-29 07:55:52","AP02EDTM":"2022-03-29 13:55:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-29","EOSDY":1096,"LSTALVDT":"2022-04-24","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3350,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.15933,"AVALU":"mg/L","BASE2":9.15933,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2019-08-18 19:55:52","ADY":142,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-370","SUBJID":"id-370","SITEID":"CHN-4","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.09845,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-28","TRTSDTM":"2019-03-29 19:55:52","TRTEDTM":"2022-03-29 13:55:52","TRT01SDTM":"2019-03-29 19:55:52","TRT01EDTM":"2021-03-29 07:55:52","TRT02SDTM":"2021-03-29 07:55:52","TRT02EDTM":"2022-03-29 13:55:52","AP01SDTM":"2019-03-29 19:55:52","AP01EDTM":"2021-03-29 07:55:52","AP02SDTM":"2021-03-29 07:55:52","AP02EDTM":"2022-03-29 13:55:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-29","EOSDY":1096,"LSTALVDT":"2022-04-24","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5697,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.85778,"AVALU":"mg/L","BASE2":9.15933,"BASE":10.85778,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.69845,"PCHG2":18.54345,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-02-19 19:55:52","ADY":327,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-370","SUBJID":"id-370","SITEID":"CHN-4","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.09845,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-28","TRTSDTM":"2019-03-29 19:55:52","TRTEDTM":"2022-03-29 13:55:52","TRT01SDTM":"2019-03-29 19:55:52","TRT01EDTM":"2021-03-29 07:55:52","TRT02SDTM":"2021-03-29 07:55:52","TRT02EDTM":"2022-03-29 13:55:52","AP01SDTM":"2019-03-29 19:55:52","AP01EDTM":"2021-03-29 07:55:52","AP02SDTM":"2021-03-29 07:55:52","AP02EDTM":"2022-03-29 13:55:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-29","EOSDY":1096,"LSTALVDT":"2022-04-24","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2175,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.08551,"AVALU":"mg/L","BASE2":9.15933,"BASE":10.85778,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.92619,"PCHG2":21.02979,"CHG":0.22773,"PCHG":2.09741,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"1","ADTM":"2021-07-06 19:55:52","ADY":830,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-370","SUBJID":"id-370","SITEID":"CHN-4","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.09845,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-28","TRTSDTM":"2019-03-29 19:55:52","TRTEDTM":"2022-03-29 13:55:52","TRT01SDTM":"2019-03-29 19:55:52","TRT01EDTM":"2021-03-29 07:55:52","TRT02SDTM":"2021-03-29 07:55:52","TRT02EDTM":"2022-03-29 13:55:52","AP01SDTM":"2019-03-29 19:55:52","AP01EDTM":"2021-03-29 07:55:52","AP02SDTM":"2021-03-29 07:55:52","AP02EDTM":"2022-03-29 13:55:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-29","EOSDY":1096,"LSTALVDT":"2022-04-24","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1003,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.45519,"AVALU":"mg/L","BASE2":9.15933,"BASE":10.85778,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.29587,"PCHG2":3.23023,"CHG":-1.40259,"PCHG":-12.91781,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-08-08 19:55:52","ADY":863,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-370","SUBJID":"id-370","SITEID":"CHN-4","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.09845,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-28","TRTSDTM":"2019-03-29 19:55:52","TRTEDTM":"2022-03-29 13:55:52","TRT01SDTM":"2019-03-29 19:55:52","TRT01EDTM":"2021-03-29 07:55:52","TRT02SDTM":"2021-03-29 07:55:52","TRT02EDTM":"2022-03-29 13:55:52","AP01SDTM":"2019-03-29 19:55:52","AP01EDTM":"2021-03-29 07:55:52","AP02SDTM":"2021-03-29 07:55:52","AP02EDTM":"2022-03-29 13:55:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-29","EOSDY":1096,"LSTALVDT":"2022-04-24","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7467,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.60682,"AVALU":"mg/L","BASE2":9.15933,"BASE":10.85778,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.55251,"PCHG2":-6.03219,"CHG":-2.25096,"PCHG":-20.73133,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-08-20 19:55:52","ADY":875,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-370","SUBJID":"id-370","SITEID":"CHN-4","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.09845,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-28","TRTSDTM":"2019-03-29 19:55:52","TRTEDTM":"2022-03-29 13:55:52","TRT01SDTM":"2019-03-29 19:55:52","TRT01EDTM":"2021-03-29 07:55:52","TRT02SDTM":"2021-03-29 07:55:52","TRT02EDTM":"2022-03-29 13:55:52","AP01SDTM":"2019-03-29 19:55:52","AP01EDTM":"2021-03-29 07:55:52","AP02SDTM":"2021-03-29 07:55:52","AP02EDTM":"2022-03-29 13:55:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-29","EOSDY":1096,"LSTALVDT":"2022-04-24","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3418,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.22295,"AVALU":"mg/L","BASE2":9.15933,"BASE":10.85778,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.93638,"PCHG2":-10.22322,"CHG":-2.63483,"PCHG":-24.26677,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-10-06 19:55:52","ADY":922,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-370","SUBJID":"id-370","SITEID":"CHN-4","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.09845,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-28","TRTSDTM":"2019-03-29 19:55:52","TRTEDTM":"2022-03-29 13:55:52","TRT01SDTM":"2019-03-29 19:55:52","TRT01EDTM":"2021-03-29 07:55:52","TRT02SDTM":"2021-03-29 07:55:52","TRT02EDTM":"2022-03-29 13:55:52","AP01SDTM":"2019-03-29 19:55:52","AP01EDTM":"2021-03-29 07:55:52","AP02SDTM":"2021-03-29 07:55:52","AP02EDTM":"2022-03-29 13:55:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-29","EOSDY":1096,"LSTALVDT":"2022-04-24","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":68,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.72158,"AVALU":"mg/L","BASE2":9.15933,"BASE":10.85778,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.43775,"PCHG2":-15.69707,"CHG":-3.1362,"PCHG":-28.88436,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-3","BTOXGR":"1","ADTM":"2021-11-17 19:55:52","ADY":964,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-370","SUBJID":"id-370","SITEID":"CHN-4","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.09845,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-28","TRTSDTM":"2019-03-29 19:55:52","TRTEDTM":"2022-03-29 13:55:52","TRT01SDTM":"2019-03-29 19:55:52","TRT01EDTM":"2021-03-29 07:55:52","TRT02SDTM":"2021-03-29 07:55:52","TRT02EDTM":"2022-03-29 13:55:52","AP01SDTM":"2019-03-29 19:55:52","AP01EDTM":"2021-03-29 07:55:52","AP02SDTM":"2021-03-29 07:55:52","AP02EDTM":"2022-03-29 13:55:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-29","EOSDY":1096,"LSTALVDT":"2022-04-24","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1612,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.14015,"AVALU":"g/L","BASE2":3.14015,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"4","BTOXGR":"0","ADTM":"2019-08-18 19:55:52","ADY":142,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-370","SUBJID":"id-370","SITEID":"CHN-4","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.09845,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-28","TRTSDTM":"2019-03-29 19:55:52","TRTEDTM":"2022-03-29 13:55:52","TRT01SDTM":"2019-03-29 19:55:52","TRT01EDTM":"2021-03-29 07:55:52","TRT02SDTM":"2021-03-29 07:55:52","TRT02EDTM":"2022-03-29 13:55:52","AP01SDTM":"2019-03-29 19:55:52","AP01EDTM":"2021-03-29 07:55:52","AP02SDTM":"2021-03-29 07:55:52","AP02EDTM":"2022-03-29 13:55:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-29","EOSDY":1096,"LSTALVDT":"2022-04-24","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7428,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80561,"AVALU":"g/L","BASE2":3.14015,"BASE":2.80561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.33454,"PCHG2":-10.65378,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-19 19:55:52","ADY":327,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-370","SUBJID":"id-370","SITEID":"CHN-4","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.09845,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-28","TRTSDTM":"2019-03-29 19:55:52","TRTEDTM":"2022-03-29 13:55:52","TRT01SDTM":"2019-03-29 19:55:52","TRT01EDTM":"2021-03-29 07:55:52","TRT02SDTM":"2021-03-29 07:55:52","TRT02EDTM":"2022-03-29 13:55:52","AP01SDTM":"2019-03-29 19:55:52","AP01EDTM":"2021-03-29 07:55:52","AP02SDTM":"2021-03-29 07:55:52","AP02EDTM":"2022-03-29 13:55:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-29","EOSDY":1096,"LSTALVDT":"2022-04-24","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6065,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79845,"AVALU":"g/L","BASE2":3.14015,"BASE":2.80561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.3417,"PCHG2":-10.88164,"CHG":-0.00716,"PCHG":-0.25503,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-06 19:55:52","ADY":830,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-370","SUBJID":"id-370","SITEID":"CHN-4","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.09845,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-28","TRTSDTM":"2019-03-29 19:55:52","TRTEDTM":"2022-03-29 13:55:52","TRT01SDTM":"2019-03-29 19:55:52","TRT01EDTM":"2021-03-29 07:55:52","TRT02SDTM":"2021-03-29 07:55:52","TRT02EDTM":"2022-03-29 13:55:52","AP01SDTM":"2019-03-29 19:55:52","AP01EDTM":"2021-03-29 07:55:52","AP02SDTM":"2021-03-29 07:55:52","AP02EDTM":"2022-03-29 13:55:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-29","EOSDY":1096,"LSTALVDT":"2022-04-24","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3121,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01034,"AVALU":"g/L","BASE2":3.14015,"BASE":2.80561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12981,"PCHG2":-4.13389,"CHG":0.20473,"PCHG":7.29733,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-08-08 19:55:52","ADY":863,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-370","SUBJID":"id-370","SITEID":"CHN-4","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.09845,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-28","TRTSDTM":"2019-03-29 19:55:52","TRTEDTM":"2022-03-29 13:55:52","TRT01SDTM":"2019-03-29 19:55:52","TRT01EDTM":"2021-03-29 07:55:52","TRT02SDTM":"2021-03-29 07:55:52","TRT02EDTM":"2022-03-29 13:55:52","AP01SDTM":"2019-03-29 19:55:52","AP01EDTM":"2021-03-29 07:55:52","AP02SDTM":"2021-03-29 07:55:52","AP02EDTM":"2022-03-29 13:55:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-29","EOSDY":1096,"LSTALVDT":"2022-04-24","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6173,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74938,"AVALU":"g/L","BASE2":3.14015,"BASE":2.80561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.39077,"PCHG2":-12.44418,"CHG":-0.05622,"PCHG":-2.00389,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-20 19:55:52","ADY":875,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-370","SUBJID":"id-370","SITEID":"CHN-4","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.09845,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-28","TRTSDTM":"2019-03-29 19:55:52","TRTEDTM":"2022-03-29 13:55:52","TRT01SDTM":"2019-03-29 19:55:52","TRT01EDTM":"2021-03-29 07:55:52","TRT02SDTM":"2021-03-29 07:55:52","TRT02EDTM":"2022-03-29 13:55:52","AP01SDTM":"2019-03-29 19:55:52","AP01EDTM":"2021-03-29 07:55:52","AP02SDTM":"2021-03-29 07:55:52","AP02EDTM":"2022-03-29 13:55:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-29","EOSDY":1096,"LSTALVDT":"2022-04-24","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8296,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74918,"AVALU":"g/L","BASE2":3.14015,"BASE":2.80561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.39097,"PCHG2":-12.45083,"CHG":-0.05643,"PCHG":-2.01133,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-06 19:55:52","ADY":922,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-370","SUBJID":"id-370","SITEID":"CHN-4","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.09845,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-28","TRTSDTM":"2019-03-29 19:55:52","TRTEDTM":"2022-03-29 13:55:52","TRT01SDTM":"2019-03-29 19:55:52","TRT01EDTM":"2021-03-29 07:55:52","TRT02SDTM":"2021-03-29 07:55:52","TRT02EDTM":"2022-03-29 13:55:52","AP01SDTM":"2019-03-29 19:55:52","AP01EDTM":"2021-03-29 07:55:52","AP02SDTM":"2021-03-29 07:55:52","AP02EDTM":"2022-03-29 13:55:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-29","EOSDY":1096,"LSTALVDT":"2022-04-24","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8295,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.12743,"AVALU":"g/L","BASE2":3.14015,"BASE":2.80561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01272,"PCHG2":-0.40513,"CHG":0.32182,"PCHG":11.47072,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-11-17 19:55:52","ADY":964,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-67","SUBJID":"id-67","SITEID":"CHN-4","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.89305,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-10","TRTSDTM":"2020-02-11 04:11:36","TRT01SDTM":"2020-02-11 04:11:36","AP01SDTM":"2020-02-11 04:11:36","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4198,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.84153,"AVALU":"U/L","BASE2":7.84153,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-04 04:11:36","ADY":175,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-67","SUBJID":"id-67","SITEID":"CHN-4","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.89305,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-10","TRTSDTM":"2020-02-11 04:11:36","TRT01SDTM":"2020-02-11 04:11:36","AP01SDTM":"2020-02-11 04:11:36","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2221,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.96423,"AVALU":"U/L","BASE2":7.84153,"BASE":25.96423,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":18.1227,"PCHG2":231.11196,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-02 04:11:36","ADY":234,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-67","SUBJID":"id-67","SITEID":"CHN-4","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.89305,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-10","TRTSDTM":"2020-02-11 04:11:36","TRT01SDTM":"2020-02-11 04:11:36","AP01SDTM":"2020-02-11 04:11:36","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7031,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.93261,"AVALU":"U/L","BASE2":7.84153,"BASE":25.96423,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":24.09109,"PCHG2":307.22449,"CHG":5.96838,"PCHG":22.98695,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-16 04:11:36","ADY":340,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-67","SUBJID":"id-67","SITEID":"CHN-4","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.89305,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-10","TRTSDTM":"2020-02-11 04:11:36","TRT01SDTM":"2020-02-11 04:11:36","AP01SDTM":"2020-02-11 04:11:36","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4660,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.77237,"AVALU":"U/L","BASE2":7.84153,"BASE":25.96423,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.06916,"PCHG2":-13.63458,"CHG":-19.19186,"PCHG":-73.91655,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-02-05 04:11:36","ADY":360,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-67","SUBJID":"id-67","SITEID":"CHN-4","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.89305,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-10","TRTSDTM":"2020-02-11 04:11:36","TRT01SDTM":"2020-02-11 04:11:36","AP01SDTM":"2020-02-11 04:11:36","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6246,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.0786,"AVALU":"U/L","BASE2":7.84153,"BASE":25.96423,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.23708,"PCHG2":41.2812,"CHG":-14.88563,"PCHG":-57.33129,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-12 04:11:36","ADY":395,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-67","SUBJID":"id-67","SITEID":"CHN-4","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.89305,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-10","TRTSDTM":"2020-02-11 04:11:36","TRT01SDTM":"2020-02-11 04:11:36","AP01SDTM":"2020-02-11 04:11:36","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7067,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":40.00362,"AVALU":"U/L","BASE2":7.84153,"BASE":25.96423,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":32.16209,"PCHG2":410.15094,"CHG":14.03939,"PCHG":54.07204,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-18 04:11:36","ADY":401,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-67","SUBJID":"id-67","SITEID":"CHN-4","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.89305,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-10","TRTSDTM":"2020-02-11 04:11:36","TRT01SDTM":"2020-02-11 04:11:36","AP01SDTM":"2020-02-11 04:11:36","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":828,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.09886,"AVALU":"U/L","BASE2":7.84153,"BASE":25.96423,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.25733,"PCHG2":156.3131,"CHG":-5.86537,"PCHG":-22.5902,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-15 04:11:36","ADY":673,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-67","SUBJID":"id-67","SITEID":"CHN-4","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.89305,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-10","TRTSDTM":"2020-02-11 04:11:36","TRT01SDTM":"2020-02-11 04:11:36","AP01SDTM":"2020-02-11 04:11:36","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":840,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.91227,"AVALU":"mg/L","BASE2":11.91227,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2020-08-04 04:11:36","ADY":175,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-67","SUBJID":"id-67","SITEID":"CHN-4","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.89305,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-10","TRTSDTM":"2020-02-11 04:11:36","TRT01SDTM":"2020-02-11 04:11:36","AP01SDTM":"2020-02-11 04:11:36","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2400,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.33128,"AVALU":"mg/L","BASE2":11.91227,"BASE":10.33128,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.58098,"PCHG2":-13.27188,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2020-10-02 04:11:36","ADY":234,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-67","SUBJID":"id-67","SITEID":"CHN-4","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.89305,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-10","TRTSDTM":"2020-02-11 04:11:36","TRT01SDTM":"2020-02-11 04:11:36","AP01SDTM":"2020-02-11 04:11:36","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5597,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.11426,"AVALU":"mg/L","BASE2":11.91227,"BASE":10.33128,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.798,"PCHG2":-23.48842,"CHG":-1.21702,"PCHG":-11.77996,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-01-16 04:11:36","ADY":340,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-67","SUBJID":"id-67","SITEID":"CHN-4","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.89305,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-10","TRTSDTM":"2020-02-11 04:11:36","TRT01SDTM":"2020-02-11 04:11:36","AP01SDTM":"2020-02-11 04:11:36","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":824,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.6787,"AVALU":"mg/L","BASE2":11.91227,"BASE":10.33128,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.23357,"PCHG2":-27.14489,"CHG":-1.65259,"PCHG":-15.99597,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-02-05 04:11:36","ADY":360,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-67","SUBJID":"id-67","SITEID":"CHN-4","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.89305,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-10","TRTSDTM":"2020-02-11 04:11:36","TRT01SDTM":"2020-02-11 04:11:36","AP01SDTM":"2020-02-11 04:11:36","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5633,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.2605,"AVALU":"mg/L","BASE2":11.91227,"BASE":10.33128,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.65176,"PCHG2":-22.26079,"CHG":-1.07078,"PCHG":-10.36447,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-03-12 04:11:36","ADY":395,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-67","SUBJID":"id-67","SITEID":"CHN-4","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.89305,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-10","TRTSDTM":"2020-02-11 04:11:36","TRT01SDTM":"2020-02-11 04:11:36","AP01SDTM":"2020-02-11 04:11:36","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3436,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.95811,"AVALU":"mg/L","BASE2":11.91227,"BASE":10.33128,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.95415,"PCHG2":-24.79927,"CHG":-1.37317,"PCHG":-13.2914,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-03-18 04:11:36","ADY":401,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-67","SUBJID":"id-67","SITEID":"CHN-4","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.89305,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-10","TRTSDTM":"2020-02-11 04:11:36","TRT01SDTM":"2020-02-11 04:11:36","AP01SDTM":"2020-02-11 04:11:36","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2079,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.69493,"AVALU":"mg/L","BASE2":11.91227,"BASE":10.33128,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.21734,"PCHG2":-18.61394,"CHG":-0.63636,"PCHG":-6.15954,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-12-15 04:11:36","ADY":673,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-67","SUBJID":"id-67","SITEID":"CHN-4","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.89305,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-10","TRTSDTM":"2020-02-11 04:11:36","TRT01SDTM":"2020-02-11 04:11:36","AP01SDTM":"2020-02-11 04:11:36","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4065,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95643,"AVALU":"g/L","BASE2":2.95643,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-04 04:11:36","ADY":175,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-67","SUBJID":"id-67","SITEID":"CHN-4","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.89305,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-10","TRTSDTM":"2020-02-11 04:11:36","TRT01SDTM":"2020-02-11 04:11:36","AP01SDTM":"2020-02-11 04:11:36","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5019,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96332,"AVALU":"g/L","BASE2":2.95643,"BASE":2.96332,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.00688,"PCHG2":0.23274,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-02 04:11:36","ADY":234,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-67","SUBJID":"id-67","SITEID":"CHN-4","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.89305,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-10","TRTSDTM":"2020-02-11 04:11:36","TRT01SDTM":"2020-02-11 04:11:36","AP01SDTM":"2020-02-11 04:11:36","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4815,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77516,"AVALU":"g/L","BASE2":2.95643,"BASE":2.96332,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18128,"PCHG2":-6.13161,"CHG":-0.18816,"PCHG":-6.34957,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-16 04:11:36","ADY":340,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-67","SUBJID":"id-67","SITEID":"CHN-4","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.89305,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-10","TRTSDTM":"2020-02-11 04:11:36","TRT01SDTM":"2020-02-11 04:11:36","AP01SDTM":"2020-02-11 04:11:36","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8076,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94576,"AVALU":"g/L","BASE2":2.95643,"BASE":2.96332,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01068,"PCHG2":-0.36108,"CHG":-0.01756,"PCHG":-0.59244,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-05 04:11:36","ADY":360,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-67","SUBJID":"id-67","SITEID":"CHN-4","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.89305,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-10","TRTSDTM":"2020-02-11 04:11:36","TRT01SDTM":"2020-02-11 04:11:36","AP01SDTM":"2020-02-11 04:11:36","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6476,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9475,"AVALU":"g/L","BASE2":2.95643,"BASE":2.96332,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00894,"PCHG2":-0.30224,"CHG":-0.01582,"PCHG":-0.53373,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-12 04:11:36","ADY":395,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-67","SUBJID":"id-67","SITEID":"CHN-4","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.89305,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-10","TRTSDTM":"2020-02-11 04:11:36","TRT01SDTM":"2020-02-11 04:11:36","AP01SDTM":"2020-02-11 04:11:36","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4256,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.06052,"AVALU":"g/L","BASE2":2.95643,"BASE":2.96332,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10408,"PCHG2":3.52055,"CHG":0.0972,"PCHG":3.28018,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-03-18 04:11:36","ADY":401,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-67","SUBJID":"id-67","SITEID":"CHN-4","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":3.89305,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-10","TRTSDTM":"2020-02-11 04:11:36","TRT01SDTM":"2020-02-11 04:11:36","AP01SDTM":"2020-02-11 04:11:36","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5829,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.69152,"AVALU":"g/L","BASE2":2.95643,"BASE":2.96332,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.26491,"PCHG2":-8.96057,"CHG":-0.27179,"PCHG":-9.17196,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-15 04:11:36","ADY":673,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-73","SUBJID":"id-73","SITEID":"CHN-4","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.86312,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-16","TRTSDTM":"2019-03-17 14:18:17","TRTEDTM":"2022-02-14 19:35:43","TRT01SDTM":"2019-03-17 14:18:17","TRT01EDTM":"2021-02-14 13:35:43","TRT02SDTM":"2021-02-14 13:35:43","TRT02EDTM":"2022-02-14 19:35:43","AP01SDTM":"2019-03-17 14:18:17","AP01EDTM":"2021-02-14 13:35:43","AP02SDTM":"2021-02-14 13:35:43","AP02EDTM":"2022-02-14 19:35:43","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1066,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-07","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3735,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.89843,"AVALU":"U/L","BASE2":21.89843,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-21 14:18:17","ADY":370,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-73","SUBJID":"id-73","SITEID":"CHN-4","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.86312,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-16","TRTSDTM":"2019-03-17 14:18:17","TRTEDTM":"2022-02-14 19:35:43","TRT01SDTM":"2019-03-17 14:18:17","TRT01EDTM":"2021-02-14 13:35:43","TRT02SDTM":"2021-02-14 13:35:43","TRT02EDTM":"2022-02-14 19:35:43","AP01SDTM":"2019-03-17 14:18:17","AP01EDTM":"2021-02-14 13:35:43","AP02SDTM":"2021-02-14 13:35:43","AP02EDTM":"2022-02-14 19:35:43","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1066,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-07","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":610,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.04497,"AVALU":"U/L","BASE2":21.89843,"BASE":31.04497,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":9.14654,"PCHG2":41.76801,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-17 14:18:17","ADY":397,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-73","SUBJID":"id-73","SITEID":"CHN-4","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.86312,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-16","TRTSDTM":"2019-03-17 14:18:17","TRTEDTM":"2022-02-14 19:35:43","TRT01SDTM":"2019-03-17 14:18:17","TRT01EDTM":"2021-02-14 13:35:43","TRT02SDTM":"2021-02-14 13:35:43","TRT02EDTM":"2022-02-14 19:35:43","AP01SDTM":"2019-03-17 14:18:17","AP01EDTM":"2021-02-14 13:35:43","AP02SDTM":"2021-02-14 13:35:43","AP02EDTM":"2022-02-14 19:35:43","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1066,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-07","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5640,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.78965,"AVALU":"U/L","BASE2":21.89843,"BASE":31.04497,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.10878,"PCHG2":-50.72867,"CHG":-20.25532,"PCHG":-65.2451,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-03 14:18:17","ADY":627,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-73","SUBJID":"id-73","SITEID":"CHN-4","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.86312,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-16","TRTSDTM":"2019-03-17 14:18:17","TRTEDTM":"2022-02-14 19:35:43","TRT01SDTM":"2019-03-17 14:18:17","TRT01EDTM":"2021-02-14 13:35:43","TRT02SDTM":"2021-02-14 13:35:43","TRT02EDTM":"2022-02-14 19:35:43","AP01SDTM":"2019-03-17 14:18:17","AP01EDTM":"2021-02-14 13:35:43","AP02SDTM":"2021-02-14 13:35:43","AP02EDTM":"2022-02-14 19:35:43","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1066,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-07","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3362,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.44664,"AVALU":"U/L","BASE2":21.89843,"BASE":31.04497,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.4518,"PCHG2":-11.19621,"CHG":-11.59833,"PCHG":-37.35978,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-25 14:18:17","ADY":739,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-73","SUBJID":"id-73","SITEID":"CHN-4","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.86312,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-16","TRTSDTM":"2019-03-17 14:18:17","TRTEDTM":"2022-02-14 19:35:43","TRT01SDTM":"2019-03-17 14:18:17","TRT01EDTM":"2021-02-14 13:35:43","TRT02SDTM":"2021-02-14 13:35:43","TRT02EDTM":"2022-02-14 19:35:43","AP01SDTM":"2019-03-17 14:18:17","AP01EDTM":"2021-02-14 13:35:43","AP02SDTM":"2021-02-14 13:35:43","AP02EDTM":"2022-02-14 19:35:43","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1066,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-07","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5267,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.3995,"AVALU":"U/L","BASE2":21.89843,"BASE":31.04497,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.50107,"PCHG2":47.95354,"CHG":1.35453,"PCHG":4.36314,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-29 14:18:17","ADY":743,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-73","SUBJID":"id-73","SITEID":"CHN-4","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.86312,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-16","TRTSDTM":"2019-03-17 14:18:17","TRTEDTM":"2022-02-14 19:35:43","TRT01SDTM":"2019-03-17 14:18:17","TRT01EDTM":"2021-02-14 13:35:43","TRT02SDTM":"2021-02-14 13:35:43","TRT02EDTM":"2022-02-14 19:35:43","AP01SDTM":"2019-03-17 14:18:17","AP01EDTM":"2021-02-14 13:35:43","AP02SDTM":"2021-02-14 13:35:43","AP02EDTM":"2022-02-14 19:35:43","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1066,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-07","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8363,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.36618,"AVALU":"U/L","BASE2":21.89843,"BASE":31.04497,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.53225,"PCHG2":-34.39631,"CHG":-16.67879,"PCHG":-53.72462,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-18 14:18:17","ADY":916,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-73","SUBJID":"id-73","SITEID":"CHN-4","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.86312,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-16","TRTSDTM":"2019-03-17 14:18:17","TRTEDTM":"2022-02-14 19:35:43","TRT01SDTM":"2019-03-17 14:18:17","TRT01EDTM":"2021-02-14 13:35:43","TRT02SDTM":"2021-02-14 13:35:43","TRT02EDTM":"2022-02-14 19:35:43","AP01SDTM":"2019-03-17 14:18:17","AP01EDTM":"2021-02-14 13:35:43","AP02SDTM":"2021-02-14 13:35:43","AP02EDTM":"2022-02-14 19:35:43","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1066,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-07","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8057,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.36287,"AVALU":"U/L","BASE2":21.89843,"BASE":31.04497,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.46444,"PCHG2":2.12087,"CHG":-8.6821,"PCHG":-27.96621,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-03 14:18:17","ADY":992,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-73","SUBJID":"id-73","SITEID":"CHN-4","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.86312,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-16","TRTSDTM":"2019-03-17 14:18:17","TRTEDTM":"2022-02-14 19:35:43","TRT01SDTM":"2019-03-17 14:18:17","TRT01EDTM":"2021-02-14 13:35:43","TRT02SDTM":"2021-02-14 13:35:43","TRT02EDTM":"2022-02-14 19:35:43","AP01SDTM":"2019-03-17 14:18:17","AP01EDTM":"2021-02-14 13:35:43","AP02SDTM":"2021-02-14 13:35:43","AP02EDTM":"2022-02-14 19:35:43","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1066,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-07","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4695,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.13481,"AVALU":"mg/L","BASE2":10.13481,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-03-21 14:18:17","ADY":370,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-73","SUBJID":"id-73","SITEID":"CHN-4","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.86312,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-16","TRTSDTM":"2019-03-17 14:18:17","TRTEDTM":"2022-02-14 19:35:43","TRT01SDTM":"2019-03-17 14:18:17","TRT01EDTM":"2021-02-14 13:35:43","TRT02SDTM":"2021-02-14 13:35:43","TRT02EDTM":"2022-02-14 19:35:43","AP01SDTM":"2019-03-17 14:18:17","AP01EDTM":"2021-02-14 13:35:43","AP02SDTM":"2021-02-14 13:35:43","AP02EDTM":"2022-02-14 19:35:43","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1066,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-07","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2418,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.86332,"AVALU":"mg/L","BASE2":10.13481,"BASE":9.86332,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.2715,"PCHG2":-2.67884,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-17 14:18:17","ADY":397,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-73","SUBJID":"id-73","SITEID":"CHN-4","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.86312,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-16","TRTSDTM":"2019-03-17 14:18:17","TRTEDTM":"2022-02-14 19:35:43","TRT01SDTM":"2019-03-17 14:18:17","TRT01EDTM":"2021-02-14 13:35:43","TRT02SDTM":"2021-02-14 13:35:43","TRT02EDTM":"2022-02-14 19:35:43","AP01SDTM":"2019-03-17 14:18:17","AP01EDTM":"2021-02-14 13:35:43","AP02SDTM":"2021-02-14 13:35:43","AP02EDTM":"2022-02-14 19:35:43","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1066,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-07","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2512,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.96031,"AVALU":"mg/L","BASE2":10.13481,"BASE":9.86332,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.17451,"PCHG2":-11.58883,"CHG":-0.90301,"PCHG":-9.15525,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-03 14:18:17","ADY":627,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-73","SUBJID":"id-73","SITEID":"CHN-4","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.86312,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-16","TRTSDTM":"2019-03-17 14:18:17","TRTEDTM":"2022-02-14 19:35:43","TRT01SDTM":"2019-03-17 14:18:17","TRT01EDTM":"2021-02-14 13:35:43","TRT02SDTM":"2021-02-14 13:35:43","TRT02EDTM":"2022-02-14 19:35:43","AP01SDTM":"2019-03-17 14:18:17","AP01EDTM":"2021-02-14 13:35:43","AP02SDTM":"2021-02-14 13:35:43","AP02EDTM":"2022-02-14 19:35:43","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1066,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-07","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1058,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.85966,"AVALU":"mg/L","BASE2":10.13481,"BASE":9.86332,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.27515,"PCHG2":-12.58188,"CHG":-1.00366,"PCHG":-10.17563,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-25 14:18:17","ADY":739,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-73","SUBJID":"id-73","SITEID":"CHN-4","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.86312,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-16","TRTSDTM":"2019-03-17 14:18:17","TRTEDTM":"2022-02-14 19:35:43","TRT01SDTM":"2019-03-17 14:18:17","TRT01EDTM":"2021-02-14 13:35:43","TRT02SDTM":"2021-02-14 13:35:43","TRT02EDTM":"2022-02-14 19:35:43","AP01SDTM":"2019-03-17 14:18:17","AP01EDTM":"2021-02-14 13:35:43","AP02SDTM":"2021-02-14 13:35:43","AP02EDTM":"2022-02-14 19:35:43","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1066,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-07","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3702,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.31773,"AVALU":"mg/L","BASE2":10.13481,"BASE":9.86332,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.81708,"PCHG2":-8.06214,"CHG":-0.54559,"PCHG":-5.53148,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-29 14:18:17","ADY":743,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-73","SUBJID":"id-73","SITEID":"CHN-4","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.86312,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-16","TRTSDTM":"2019-03-17 14:18:17","TRTEDTM":"2022-02-14 19:35:43","TRT01SDTM":"2019-03-17 14:18:17","TRT01EDTM":"2021-02-14 13:35:43","TRT02SDTM":"2021-02-14 13:35:43","TRT02EDTM":"2022-02-14 19:35:43","AP01SDTM":"2019-03-17 14:18:17","AP01EDTM":"2021-02-14 13:35:43","AP02SDTM":"2021-02-14 13:35:43","AP02EDTM":"2022-02-14 19:35:43","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1066,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-07","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3532,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.6964,"AVALU":"mg/L","BASE2":10.13481,"BASE":9.86332,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.43841,"PCHG2":-33.92675,"CHG":-3.16692,"PCHG":-32.10804,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-09-18 14:18:17","ADY":916,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-73","SUBJID":"id-73","SITEID":"CHN-4","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.86312,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-16","TRTSDTM":"2019-03-17 14:18:17","TRTEDTM":"2022-02-14 19:35:43","TRT01SDTM":"2019-03-17 14:18:17","TRT01EDTM":"2021-02-14 13:35:43","TRT02SDTM":"2021-02-14 13:35:43","TRT02EDTM":"2022-02-14 19:35:43","AP01SDTM":"2019-03-17 14:18:17","AP01EDTM":"2021-02-14 13:35:43","AP02SDTM":"2021-02-14 13:35:43","AP02EDTM":"2022-02-14 19:35:43","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1066,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-07","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7981,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.02707,"AVALU":"mg/L","BASE2":10.13481,"BASE":9.86332,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10775,"PCHG2":-1.06312,"CHG":0.16375,"PCHG":1.66019,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-12-03 14:18:17","ADY":992,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-73","SUBJID":"id-73","SITEID":"CHN-4","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.86312,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-16","TRTSDTM":"2019-03-17 14:18:17","TRTEDTM":"2022-02-14 19:35:43","TRT01SDTM":"2019-03-17 14:18:17","TRT01EDTM":"2021-02-14 13:35:43","TRT02SDTM":"2021-02-14 13:35:43","TRT02EDTM":"2022-02-14 19:35:43","AP01SDTM":"2019-03-17 14:18:17","AP01EDTM":"2021-02-14 13:35:43","AP02SDTM":"2021-02-14 13:35:43","AP02EDTM":"2022-02-14 19:35:43","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1066,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-07","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4645,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84699,"AVALU":"g/L","BASE2":2.84699,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-21 14:18:17","ADY":370,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-73","SUBJID":"id-73","SITEID":"CHN-4","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.86312,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-16","TRTSDTM":"2019-03-17 14:18:17","TRTEDTM":"2022-02-14 19:35:43","TRT01SDTM":"2019-03-17 14:18:17","TRT01EDTM":"2021-02-14 13:35:43","TRT02SDTM":"2021-02-14 13:35:43","TRT02EDTM":"2022-02-14 19:35:43","AP01SDTM":"2019-03-17 14:18:17","AP01EDTM":"2021-02-14 13:35:43","AP02SDTM":"2021-02-14 13:35:43","AP02EDTM":"2022-02-14 19:35:43","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1066,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-07","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1488,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93015,"AVALU":"g/L","BASE2":2.84699,"BASE":2.93015,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.08316,"PCHG2":2.92102,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-17 14:18:17","ADY":397,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-73","SUBJID":"id-73","SITEID":"CHN-4","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.86312,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-16","TRTSDTM":"2019-03-17 14:18:17","TRTEDTM":"2022-02-14 19:35:43","TRT01SDTM":"2019-03-17 14:18:17","TRT01EDTM":"2021-02-14 13:35:43","TRT02SDTM":"2021-02-14 13:35:43","TRT02EDTM":"2022-02-14 19:35:43","AP01SDTM":"2019-03-17 14:18:17","AP01EDTM":"2021-02-14 13:35:43","AP02SDTM":"2021-02-14 13:35:43","AP02EDTM":"2022-02-14 19:35:43","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1066,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-07","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2740,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95546,"AVALU":"g/L","BASE2":2.84699,"BASE":2.93015,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10847,"PCHG2":3.80985,"CHG":0.0253,"PCHG":0.8636,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-03 14:18:17","ADY":627,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-73","SUBJID":"id-73","SITEID":"CHN-4","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.86312,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-16","TRTSDTM":"2019-03-17 14:18:17","TRTEDTM":"2022-02-14 19:35:43","TRT01SDTM":"2019-03-17 14:18:17","TRT01EDTM":"2021-02-14 13:35:43","TRT02SDTM":"2021-02-14 13:35:43","TRT02EDTM":"2022-02-14 19:35:43","AP01SDTM":"2019-03-17 14:18:17","AP01EDTM":"2021-02-14 13:35:43","AP02SDTM":"2021-02-14 13:35:43","AP02EDTM":"2022-02-14 19:35:43","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1066,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-07","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3347,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80704,"AVALU":"g/L","BASE2":2.84699,"BASE":2.93015,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03995,"PCHG2":-1.40332,"CHG":-0.12311,"PCHG":-4.2016,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-25 14:18:17","ADY":739,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-73","SUBJID":"id-73","SITEID":"CHN-4","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.86312,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-16","TRTSDTM":"2019-03-17 14:18:17","TRTEDTM":"2022-02-14 19:35:43","TRT01SDTM":"2019-03-17 14:18:17","TRT01EDTM":"2021-02-14 13:35:43","TRT02SDTM":"2021-02-14 13:35:43","TRT02EDTM":"2022-02-14 19:35:43","AP01SDTM":"2019-03-17 14:18:17","AP01EDTM":"2021-02-14 13:35:43","AP02SDTM":"2021-02-14 13:35:43","AP02EDTM":"2022-02-14 19:35:43","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1066,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-07","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":964,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87683,"AVALU":"g/L","BASE2":2.84699,"BASE":2.93015,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02984,"PCHG2":1.04807,"CHG":-0.05332,"PCHG":-1.81979,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-29 14:18:17","ADY":743,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-73","SUBJID":"id-73","SITEID":"CHN-4","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.86312,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-16","TRTSDTM":"2019-03-17 14:18:17","TRTEDTM":"2022-02-14 19:35:43","TRT01SDTM":"2019-03-17 14:18:17","TRT01EDTM":"2021-02-14 13:35:43","TRT02SDTM":"2021-02-14 13:35:43","TRT02EDTM":"2022-02-14 19:35:43","AP01SDTM":"2019-03-17 14:18:17","AP01EDTM":"2021-02-14 13:35:43","AP02SDTM":"2021-02-14 13:35:43","AP02EDTM":"2022-02-14 19:35:43","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1066,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-07","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1192,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02255,"AVALU":"g/L","BASE2":2.84699,"BASE":2.93015,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17556,"PCHG2":6.16646,"CHG":0.0924,"PCHG":3.15333,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-09-18 14:18:17","ADY":916,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-4-id-73","SUBJID":"id-73","SITEID":"CHN-4","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-4","INVNAM":"Dr. CHN-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.86312,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-03-16","TRTSDTM":"2019-03-17 14:18:17","TRTEDTM":"2022-02-14 19:35:43","TRT01SDTM":"2019-03-17 14:18:17","TRT01EDTM":"2021-02-14 13:35:43","TRT02SDTM":"2021-02-14 13:35:43","TRT02EDTM":"2022-02-14 19:35:43","AP01SDTM":"2019-03-17 14:18:17","AP01EDTM":"2021-02-14 13:35:43","AP02SDTM":"2021-02-14 13:35:43","AP02EDTM":"2022-02-14 19:35:43","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":1066,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-07","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4496,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85634,"AVALU":"g/L","BASE2":2.84699,"BASE":2.93015,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00935,"PCHG2":0.32852,"CHG":-0.07381,"PCHG":-2.51892,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-03 14:18:17","ADY":992,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-108","SUBJID":"id-108","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.74721,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-11 06:10:06","TRTEDTM":"2022-02-13 05:36:22","TRT01SDTM":"2019-09-11 06:10:06","TRT01EDTM":"2021-02-12 23:36:22","TRT02SDTM":"2021-02-12 23:36:22","TRT02EDTM":"2022-02-13 05:36:22","AP01SDTM":"2019-09-11 06:10:06","AP01EDTM":"2021-02-12 23:36:22","AP02SDTM":"2021-02-12 23:36:22","AP02EDTM":"2022-02-13 05:36:22","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":886,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":935,"ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":219,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.23408,"AVALU":"U/L","BASE2":5.23408,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-4","BTOXGR":"0","ADTM":"2019-09-28 06:10:06","ADY":17,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-108","SUBJID":"id-108","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.74721,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-11 06:10:06","TRTEDTM":"2022-02-13 05:36:22","TRT01SDTM":"2019-09-11 06:10:06","TRT01EDTM":"2021-02-12 23:36:22","TRT02SDTM":"2021-02-12 23:36:22","TRT02EDTM":"2022-02-13 05:36:22","AP01SDTM":"2019-09-11 06:10:06","AP01EDTM":"2021-02-12 23:36:22","AP02SDTM":"2021-02-12 23:36:22","AP02EDTM":"2022-02-13 05:36:22","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":886,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":935,"ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2231,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.31853,"AVALU":"U/L","BASE2":5.23408,"BASE":11.31853,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":6.08445,"PCHG2":116.24682,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-03 06:10:06","ADY":205,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-108","SUBJID":"id-108","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.74721,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-11 06:10:06","TRTEDTM":"2022-02-13 05:36:22","TRT01SDTM":"2019-09-11 06:10:06","TRT01EDTM":"2021-02-12 23:36:22","TRT02SDTM":"2021-02-12 23:36:22","TRT02EDTM":"2022-02-13 05:36:22","AP01SDTM":"2019-09-11 06:10:06","AP01EDTM":"2021-02-12 23:36:22","AP02SDTM":"2021-02-12 23:36:22","AP02EDTM":"2022-02-13 05:36:22","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":886,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":935,"ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6672,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.6604,"AVALU":"U/L","BASE2":5.23408,"BASE":11.31853,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.57368,"PCHG2":-10.96044,"CHG":-6.65813,"PCHG":-58.82503,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-07-06 06:10:06","ADY":299,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-108","SUBJID":"id-108","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.74721,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-11 06:10:06","TRTEDTM":"2022-02-13 05:36:22","TRT01SDTM":"2019-09-11 06:10:06","TRT01EDTM":"2021-02-12 23:36:22","TRT02SDTM":"2021-02-12 23:36:22","TRT02EDTM":"2022-02-13 05:36:22","AP01SDTM":"2019-09-11 06:10:06","AP01EDTM":"2021-02-12 23:36:22","AP02SDTM":"2021-02-12 23:36:22","AP02EDTM":"2022-02-13 05:36:22","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":886,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":935,"ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7666,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.52459,"AVALU":"U/L","BASE2":5.23408,"BASE":11.31853,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.29052,"PCHG2":311.23947,"CHG":10.20607,"PCHG":90.17134,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-29 06:10:06","ADY":384,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-108","SUBJID":"id-108","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.74721,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-11 06:10:06","TRTEDTM":"2022-02-13 05:36:22","TRT01SDTM":"2019-09-11 06:10:06","TRT01EDTM":"2021-02-12 23:36:22","TRT02SDTM":"2021-02-12 23:36:22","TRT02EDTM":"2022-02-13 05:36:22","AP01SDTM":"2019-09-11 06:10:06","AP01EDTM":"2021-02-12 23:36:22","AP02SDTM":"2021-02-12 23:36:22","AP02EDTM":"2022-02-13 05:36:22","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":886,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":935,"ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7145,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.22011,"AVALU":"U/L","BASE2":5.23408,"BASE":11.31853,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.98603,"PCHG2":228.99986,"CHG":5.90158,"PCHG":52.1409,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-27 06:10:06","ADY":473,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-108","SUBJID":"id-108","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.74721,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-11 06:10:06","TRTEDTM":"2022-02-13 05:36:22","TRT01SDTM":"2019-09-11 06:10:06","TRT01EDTM":"2021-02-12 23:36:22","TRT02SDTM":"2021-02-12 23:36:22","TRT02EDTM":"2022-02-13 05:36:22","AP01SDTM":"2019-09-11 06:10:06","AP01EDTM":"2021-02-12 23:36:22","AP02SDTM":"2021-02-12 23:36:22","AP02EDTM":"2022-02-13 05:36:22","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":886,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":935,"ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3461,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.07108,"AVALU":"U/L","BASE2":5.23408,"BASE":11.31853,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.837,"PCHG2":283.46928,"CHG":8.75255,"PCHG":77.32945,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-10 06:10:06","ADY":577,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-108","SUBJID":"id-108","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.74721,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-11 06:10:06","TRTEDTM":"2022-02-13 05:36:22","TRT01SDTM":"2019-09-11 06:10:06","TRT01EDTM":"2021-02-12 23:36:22","TRT02SDTM":"2021-02-12 23:36:22","TRT02EDTM":"2022-02-13 05:36:22","AP01SDTM":"2019-09-11 06:10:06","AP01EDTM":"2021-02-12 23:36:22","AP02SDTM":"2021-02-12 23:36:22","AP02EDTM":"2022-02-13 05:36:22","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":886,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":935,"ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":480,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.57662,"AVALU":"U/L","BASE2":5.23408,"BASE":11.31853,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.34254,"PCHG2":216.70562,"CHG":5.25809,"PCHG":46.45562,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-05 06:10:06","ADY":663,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-108","SUBJID":"id-108","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.74721,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-11 06:10:06","TRTEDTM":"2022-02-13 05:36:22","TRT01SDTM":"2019-09-11 06:10:06","TRT01EDTM":"2021-02-12 23:36:22","TRT02SDTM":"2021-02-12 23:36:22","TRT02EDTM":"2022-02-13 05:36:22","AP01SDTM":"2019-09-11 06:10:06","AP01EDTM":"2021-02-12 23:36:22","AP02SDTM":"2021-02-12 23:36:22","AP02EDTM":"2022-02-13 05:36:22","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":886,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":935,"ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4329,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.45437,"AVALU":"mg/L","BASE2":8.45437,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-28 06:10:06","ADY":17,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-108","SUBJID":"id-108","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.74721,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-11 06:10:06","TRTEDTM":"2022-02-13 05:36:22","TRT01SDTM":"2019-09-11 06:10:06","TRT01EDTM":"2021-02-12 23:36:22","TRT02SDTM":"2021-02-12 23:36:22","TRT02EDTM":"2022-02-13 05:36:22","AP01SDTM":"2019-09-11 06:10:06","AP01EDTM":"2021-02-12 23:36:22","AP02SDTM":"2021-02-12 23:36:22","AP02EDTM":"2022-02-13 05:36:22","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":886,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":935,"ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6508,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.31089,"AVALU":"mg/L","BASE2":8.45437,"BASE":9.31089,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.85653,"PCHG2":10.13118,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-03 06:10:06","ADY":205,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-108","SUBJID":"id-108","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.74721,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-11 06:10:06","TRTEDTM":"2022-02-13 05:36:22","TRT01SDTM":"2019-09-11 06:10:06","TRT01EDTM":"2021-02-12 23:36:22","TRT02SDTM":"2021-02-12 23:36:22","TRT02EDTM":"2022-02-13 05:36:22","AP01SDTM":"2019-09-11 06:10:06","AP01EDTM":"2021-02-12 23:36:22","AP02SDTM":"2021-02-12 23:36:22","AP02EDTM":"2022-02-13 05:36:22","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":886,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":935,"ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5023,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.5811,"AVALU":"mg/L","BASE2":8.45437,"BASE":9.31089,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12673,"PCHG2":1.49901,"CHG":-0.7298,"PCHG":-7.83808,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-06 06:10:06","ADY":299,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-108","SUBJID":"id-108","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.74721,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-11 06:10:06","TRTEDTM":"2022-02-13 05:36:22","TRT01SDTM":"2019-09-11 06:10:06","TRT01EDTM":"2021-02-12 23:36:22","TRT02SDTM":"2021-02-12 23:36:22","TRT02EDTM":"2022-02-13 05:36:22","AP01SDTM":"2019-09-11 06:10:06","AP01EDTM":"2021-02-12 23:36:22","AP02SDTM":"2021-02-12 23:36:22","AP02EDTM":"2022-02-13 05:36:22","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":886,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":935,"ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2296,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.91997,"AVALU":"mg/L","BASE2":8.45437,"BASE":9.31089,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.4656,"PCHG2":17.33545,"CHG":0.60907,"PCHG":6.54153,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-29 06:10:06","ADY":384,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-108","SUBJID":"id-108","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.74721,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-11 06:10:06","TRTEDTM":"2022-02-13 05:36:22","TRT01SDTM":"2019-09-11 06:10:06","TRT01EDTM":"2021-02-12 23:36:22","TRT02SDTM":"2021-02-12 23:36:22","TRT02EDTM":"2022-02-13 05:36:22","AP01SDTM":"2019-09-11 06:10:06","AP01EDTM":"2021-02-12 23:36:22","AP02SDTM":"2021-02-12 23:36:22","AP02EDTM":"2022-02-13 05:36:22","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":886,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":935,"ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2433,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.61913,"AVALU":"mg/L","BASE2":8.45437,"BASE":9.31089,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.16476,"PCHG2":13.77702,"CHG":0.30823,"PCHG":3.31045,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-27 06:10:06","ADY":473,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-108","SUBJID":"id-108","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.74721,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-11 06:10:06","TRTEDTM":"2022-02-13 05:36:22","TRT01SDTM":"2019-09-11 06:10:06","TRT01EDTM":"2021-02-12 23:36:22","TRT02SDTM":"2021-02-12 23:36:22","TRT02EDTM":"2022-02-13 05:36:22","AP01SDTM":"2019-09-11 06:10:06","AP01EDTM":"2021-02-12 23:36:22","AP02SDTM":"2021-02-12 23:36:22","AP02EDTM":"2022-02-13 05:36:22","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":886,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":935,"ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2101,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.73923,"AVALU":"mg/L","BASE2":8.45437,"BASE":9.31089,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.28487,"PCHG2":3.36945,"CHG":-0.57166,"PCHG":-6.13971,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-10 06:10:06","ADY":577,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-108","SUBJID":"id-108","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.74721,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-11 06:10:06","TRTEDTM":"2022-02-13 05:36:22","TRT01SDTM":"2019-09-11 06:10:06","TRT01EDTM":"2021-02-12 23:36:22","TRT02SDTM":"2021-02-12 23:36:22","TRT02EDTM":"2022-02-13 05:36:22","AP01SDTM":"2019-09-11 06:10:06","AP01EDTM":"2021-02-12 23:36:22","AP02SDTM":"2021-02-12 23:36:22","AP02EDTM":"2022-02-13 05:36:22","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":886,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":935,"ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1627,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.27925,"AVALU":"mg/L","BASE2":8.45437,"BASE":9.31089,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17511,"PCHG2":-2.07128,"CHG":-1.03164,"PCHG":-11.07993,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-05 06:10:06","ADY":663,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-108","SUBJID":"id-108","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.74721,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-11 06:10:06","TRTEDTM":"2022-02-13 05:36:22","TRT01SDTM":"2019-09-11 06:10:06","TRT01EDTM":"2021-02-12 23:36:22","TRT02SDTM":"2021-02-12 23:36:22","TRT02EDTM":"2022-02-13 05:36:22","AP01SDTM":"2019-09-11 06:10:06","AP01EDTM":"2021-02-12 23:36:22","AP02SDTM":"2021-02-12 23:36:22","AP02EDTM":"2022-02-13 05:36:22","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":886,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":935,"ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5498,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91453,"AVALU":"g/L","BASE2":2.91453,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-28 06:10:06","ADY":17,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-108","SUBJID":"id-108","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.74721,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-11 06:10:06","TRTEDTM":"2022-02-13 05:36:22","TRT01SDTM":"2019-09-11 06:10:06","TRT01EDTM":"2021-02-12 23:36:22","TRT02SDTM":"2021-02-12 23:36:22","TRT02EDTM":"2022-02-13 05:36:22","AP01SDTM":"2019-09-11 06:10:06","AP01EDTM":"2021-02-12 23:36:22","AP02SDTM":"2021-02-12 23:36:22","AP02EDTM":"2022-02-13 05:36:22","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":886,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":935,"ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1147,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98616,"AVALU":"g/L","BASE2":2.91453,"BASE":2.98616,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.07163,"PCHG2":2.45766,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-03 06:10:06","ADY":205,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-108","SUBJID":"id-108","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.74721,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-11 06:10:06","TRTEDTM":"2022-02-13 05:36:22","TRT01SDTM":"2019-09-11 06:10:06","TRT01EDTM":"2021-02-12 23:36:22","TRT02SDTM":"2021-02-12 23:36:22","TRT02EDTM":"2022-02-13 05:36:22","AP01SDTM":"2019-09-11 06:10:06","AP01EDTM":"2021-02-12 23:36:22","AP02SDTM":"2021-02-12 23:36:22","AP02EDTM":"2022-02-13 05:36:22","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":886,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":935,"ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2261,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93328,"AVALU":"g/L","BASE2":2.91453,"BASE":2.98616,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01875,"PCHG2":0.64338,"CHG":-0.05288,"PCHG":-1.77077,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-06 06:10:06","ADY":299,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-108","SUBJID":"id-108","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.74721,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-11 06:10:06","TRTEDTM":"2022-02-13 05:36:22","TRT01SDTM":"2019-09-11 06:10:06","TRT01EDTM":"2021-02-12 23:36:22","TRT02SDTM":"2021-02-12 23:36:22","TRT02EDTM":"2022-02-13 05:36:22","AP01SDTM":"2019-09-11 06:10:06","AP01EDTM":"2021-02-12 23:36:22","AP02SDTM":"2021-02-12 23:36:22","AP02EDTM":"2022-02-13 05:36:22","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":886,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":935,"ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2708,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92183,"AVALU":"g/L","BASE2":2.91453,"BASE":2.98616,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0073,"PCHG2":0.2504,"CHG":-0.06433,"PCHG":-2.15431,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-29 06:10:06","ADY":384,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-108","SUBJID":"id-108","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.74721,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-11 06:10:06","TRTEDTM":"2022-02-13 05:36:22","TRT01SDTM":"2019-09-11 06:10:06","TRT01EDTM":"2021-02-12 23:36:22","TRT02SDTM":"2021-02-12 23:36:22","TRT02EDTM":"2022-02-13 05:36:22","AP01SDTM":"2019-09-11 06:10:06","AP01EDTM":"2021-02-12 23:36:22","AP02SDTM":"2021-02-12 23:36:22","AP02EDTM":"2022-02-13 05:36:22","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":886,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":935,"ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1776,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86587,"AVALU":"g/L","BASE2":2.91453,"BASE":2.98616,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04866,"PCHG2":-1.66952,"CHG":-0.12029,"PCHG":-4.02819,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-27 06:10:06","ADY":473,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-108","SUBJID":"id-108","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.74721,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-11 06:10:06","TRTEDTM":"2022-02-13 05:36:22","TRT01SDTM":"2019-09-11 06:10:06","TRT01EDTM":"2021-02-12 23:36:22","TRT02SDTM":"2021-02-12 23:36:22","TRT02EDTM":"2022-02-13 05:36:22","AP01SDTM":"2019-09-11 06:10:06","AP01EDTM":"2021-02-12 23:36:22","AP02SDTM":"2021-02-12 23:36:22","AP02EDTM":"2022-02-13 05:36:22","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":886,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":935,"ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6097,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96239,"AVALU":"g/L","BASE2":2.91453,"BASE":2.98616,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04786,"PCHG2":1.64212,"CHG":-0.02377,"PCHG":-0.79598,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-10 06:10:06","ADY":577,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-108","SUBJID":"id-108","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.74721,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-11 06:10:06","TRTEDTM":"2022-02-13 05:36:22","TRT01SDTM":"2019-09-11 06:10:06","TRT01EDTM":"2021-02-12 23:36:22","TRT02SDTM":"2021-02-12 23:36:22","TRT02EDTM":"2022-02-13 05:36:22","AP01SDTM":"2019-09-11 06:10:06","AP01EDTM":"2021-02-12 23:36:22","AP02SDTM":"2021-02-12 23:36:22","AP02EDTM":"2022-02-13 05:36:22","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":886,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":935,"ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4505,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77771,"AVALU":"g/L","BASE2":2.91453,"BASE":2.98616,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13682,"PCHG2":-4.69428,"CHG":-0.20845,"PCHG":-6.98039,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-05 06:10:06","ADY":663,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-159","SUBJID":"id-159","SITEID":"CHN-5","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.54626,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-27 04:18:29","TRTEDTM":"2022-05-26 22:18:29","TRT01SDTM":"2019-05-27 04:18:29","TRT01EDTM":"2021-05-26 16:18:29","TRT02SDTM":"2021-05-26 16:18:29","TRT02EDTM":"2022-05-26 22:18:29","AP01SDTM":"2019-05-27 04:18:29","AP01EDTM":"2021-05-26 16:18:29","AP02SDTM":"2021-05-26 16:18:29","AP02EDTM":"2022-05-26 22:18:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-26","EOSDY":1096,"LSTALVDT":"2022-06-11","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3384,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.68533,"AVALU":"U/L","BASE2":25.68533,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-05-27 04:18:29","ADY":0,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-159","SUBJID":"id-159","SITEID":"CHN-5","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.54626,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-27 04:18:29","TRTEDTM":"2022-05-26 22:18:29","TRT01SDTM":"2019-05-27 04:18:29","TRT01EDTM":"2021-05-26 16:18:29","TRT02SDTM":"2021-05-26 16:18:29","TRT02EDTM":"2022-05-26 22:18:29","AP01SDTM":"2019-05-27 04:18:29","AP01EDTM":"2021-05-26 16:18:29","AP02SDTM":"2021-05-26 16:18:29","AP02EDTM":"2022-05-26 22:18:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-26","EOSDY":1096,"LSTALVDT":"2022-06-11","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8311,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.46683,"AVALU":"U/L","BASE2":25.68533,"BASE":16.46683,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-9.2185,"PCHG2":-35.89014,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-09 04:18:29","ADY":227,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-159","SUBJID":"id-159","SITEID":"CHN-5","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.54626,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-27 04:18:29","TRTEDTM":"2022-05-26 22:18:29","TRT01SDTM":"2019-05-27 04:18:29","TRT01EDTM":"2021-05-26 16:18:29","TRT02SDTM":"2021-05-26 16:18:29","TRT02EDTM":"2022-05-26 22:18:29","AP01SDTM":"2019-05-27 04:18:29","AP01EDTM":"2021-05-26 16:18:29","AP02SDTM":"2021-05-26 16:18:29","AP02EDTM":"2022-05-26 22:18:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-26","EOSDY":1096,"LSTALVDT":"2022-06-11","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5834,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.44741,"AVALU":"U/L","BASE2":25.68533,"BASE":16.46683,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.76208,"PCHG2":10.75352,"CHG":11.98058,"PCHG":72.75584,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-11 04:18:29","ADY":260,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-159","SUBJID":"id-159","SITEID":"CHN-5","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.54626,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-27 04:18:29","TRTEDTM":"2022-05-26 22:18:29","TRT01SDTM":"2019-05-27 04:18:29","TRT01EDTM":"2021-05-26 16:18:29","TRT02SDTM":"2021-05-26 16:18:29","TRT02EDTM":"2022-05-26 22:18:29","AP01SDTM":"2019-05-27 04:18:29","AP01EDTM":"2021-05-26 16:18:29","AP02SDTM":"2021-05-26 16:18:29","AP02EDTM":"2022-05-26 22:18:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-26","EOSDY":1096,"LSTALVDT":"2022-06-11","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4432,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.46822,"AVALU":"U/L","BASE2":25.68533,"BASE":16.46683,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.78289,"PCHG2":10.83456,"CHG":12.00139,"PCHG":72.88225,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-01 04:18:29","ADY":401,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-159","SUBJID":"id-159","SITEID":"CHN-5","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.54626,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-27 04:18:29","TRTEDTM":"2022-05-26 22:18:29","TRT01SDTM":"2019-05-27 04:18:29","TRT01EDTM":"2021-05-26 16:18:29","TRT02SDTM":"2021-05-26 16:18:29","TRT02EDTM":"2022-05-26 22:18:29","AP01SDTM":"2019-05-27 04:18:29","AP01EDTM":"2021-05-26 16:18:29","AP02SDTM":"2021-05-26 16:18:29","AP02EDTM":"2022-05-26 22:18:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-26","EOSDY":1096,"LSTALVDT":"2022-06-11","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1090,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.59768,"AVALU":"U/L","BASE2":25.68533,"BASE":16.46683,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.08765,"PCHG2":-47.06052,"CHG":-2.86915,"PCHG":-17.4238,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-05 04:18:29","ADY":497,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-159","SUBJID":"id-159","SITEID":"CHN-5","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.54626,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-27 04:18:29","TRTEDTM":"2022-05-26 22:18:29","TRT01SDTM":"2019-05-27 04:18:29","TRT01EDTM":"2021-05-26 16:18:29","TRT02SDTM":"2021-05-26 16:18:29","TRT02EDTM":"2022-05-26 22:18:29","AP01SDTM":"2019-05-27 04:18:29","AP01EDTM":"2021-05-26 16:18:29","AP02SDTM":"2021-05-26 16:18:29","AP02EDTM":"2022-05-26 22:18:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-26","EOSDY":1096,"LSTALVDT":"2022-06-11","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4883,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.92543,"AVALU":"U/L","BASE2":25.68533,"BASE":16.46683,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.7599,"PCHG2":-37.99797,"CHG":-0.5414,"PCHG":-3.28783,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-17 04:18:29","ADY":632,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-159","SUBJID":"id-159","SITEID":"CHN-5","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.54626,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-27 04:18:29","TRTEDTM":"2022-05-26 22:18:29","TRT01SDTM":"2019-05-27 04:18:29","TRT01EDTM":"2021-05-26 16:18:29","TRT02SDTM":"2021-05-26 16:18:29","TRT02EDTM":"2022-05-26 22:18:29","AP01SDTM":"2019-05-27 04:18:29","AP01EDTM":"2021-05-26 16:18:29","AP02SDTM":"2021-05-26 16:18:29","AP02EDTM":"2022-05-26 22:18:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-26","EOSDY":1096,"LSTALVDT":"2022-06-11","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5921,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.01437,"AVALU":"U/L","BASE2":25.68533,"BASE":16.46683,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.67096,"PCHG2":-6.5055,"CHG":7.54754,"PCHG":45.83483,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-05 04:18:29","ADY":1074,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-159","SUBJID":"id-159","SITEID":"CHN-5","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.54626,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-27 04:18:29","TRTEDTM":"2022-05-26 22:18:29","TRT01SDTM":"2019-05-27 04:18:29","TRT01EDTM":"2021-05-26 16:18:29","TRT02SDTM":"2021-05-26 16:18:29","TRT02EDTM":"2022-05-26 22:18:29","AP01SDTM":"2019-05-27 04:18:29","AP01EDTM":"2021-05-26 16:18:29","AP02SDTM":"2021-05-26 16:18:29","AP02EDTM":"2022-05-26 22:18:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-26","EOSDY":1096,"LSTALVDT":"2022-06-11","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2116,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.30252,"AVALU":"mg/L","BASE2":8.30252,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-05-27 04:18:29","ADY":0,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-159","SUBJID":"id-159","SITEID":"CHN-5","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.54626,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-27 04:18:29","TRTEDTM":"2022-05-26 22:18:29","TRT01SDTM":"2019-05-27 04:18:29","TRT01EDTM":"2021-05-26 16:18:29","TRT02SDTM":"2021-05-26 16:18:29","TRT02EDTM":"2022-05-26 22:18:29","AP01SDTM":"2019-05-27 04:18:29","AP01EDTM":"2021-05-26 16:18:29","AP02SDTM":"2021-05-26 16:18:29","AP02EDTM":"2022-05-26 22:18:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-26","EOSDY":1096,"LSTALVDT":"2022-06-11","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5309,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.73391,"AVALU":"mg/L","BASE2":8.30252,"BASE":8.73391,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.43138,"PCHG2":5.19582,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-09 04:18:29","ADY":227,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-159","SUBJID":"id-159","SITEID":"CHN-5","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.54626,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-27 04:18:29","TRTEDTM":"2022-05-26 22:18:29","TRT01SDTM":"2019-05-27 04:18:29","TRT01EDTM":"2021-05-26 16:18:29","TRT02SDTM":"2021-05-26 16:18:29","TRT02EDTM":"2022-05-26 22:18:29","AP01SDTM":"2019-05-27 04:18:29","AP01EDTM":"2021-05-26 16:18:29","AP02SDTM":"2021-05-26 16:18:29","AP02EDTM":"2022-05-26 22:18:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-26","EOSDY":1096,"LSTALVDT":"2022-06-11","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2143,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.81804,"AVALU":"mg/L","BASE2":8.30252,"BASE":8.73391,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.51551,"PCHG2":6.20911,"CHG":0.08413,"PCHG":0.96324,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-11 04:18:29","ADY":260,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-159","SUBJID":"id-159","SITEID":"CHN-5","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.54626,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-27 04:18:29","TRTEDTM":"2022-05-26 22:18:29","TRT01SDTM":"2019-05-27 04:18:29","TRT01EDTM":"2021-05-26 16:18:29","TRT02SDTM":"2021-05-26 16:18:29","TRT02EDTM":"2022-05-26 22:18:29","AP01SDTM":"2019-05-27 04:18:29","AP01EDTM":"2021-05-26 16:18:29","AP02SDTM":"2021-05-26 16:18:29","AP02EDTM":"2022-05-26 22:18:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-26","EOSDY":1096,"LSTALVDT":"2022-06-11","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5586,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.88015,"AVALU":"mg/L","BASE2":8.30252,"BASE":8.73391,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.57762,"PCHG2":19.00175,"CHG":1.14624,"PCHG":13.12404,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-01 04:18:29","ADY":401,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-159","SUBJID":"id-159","SITEID":"CHN-5","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.54626,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-27 04:18:29","TRTEDTM":"2022-05-26 22:18:29","TRT01SDTM":"2019-05-27 04:18:29","TRT01EDTM":"2021-05-26 16:18:29","TRT02SDTM":"2021-05-26 16:18:29","TRT02EDTM":"2022-05-26 22:18:29","AP01SDTM":"2019-05-27 04:18:29","AP01EDTM":"2021-05-26 16:18:29","AP02SDTM":"2021-05-26 16:18:29","AP02EDTM":"2022-05-26 22:18:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-26","EOSDY":1096,"LSTALVDT":"2022-06-11","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6968,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.15476,"AVALU":"mg/L","BASE2":8.30252,"BASE":8.73391,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.85223,"PCHG2":22.30927,"CHG":1.42085,"PCHG":16.26819,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-10-05 04:18:29","ADY":497,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-159","SUBJID":"id-159","SITEID":"CHN-5","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.54626,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-27 04:18:29","TRTEDTM":"2022-05-26 22:18:29","TRT01SDTM":"2019-05-27 04:18:29","TRT01EDTM":"2021-05-26 16:18:29","TRT02SDTM":"2021-05-26 16:18:29","TRT02EDTM":"2022-05-26 22:18:29","AP01SDTM":"2019-05-27 04:18:29","AP01EDTM":"2021-05-26 16:18:29","AP02SDTM":"2021-05-26 16:18:29","AP02EDTM":"2022-05-26 22:18:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-26","EOSDY":1096,"LSTALVDT":"2022-06-11","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1674,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.23763,"AVALU":"mg/L","BASE2":8.30252,"BASE":8.73391,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0649,"PCHG2":-0.78166,"CHG":-0.49628,"PCHG":-5.68223,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-17 04:18:29","ADY":632,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-159","SUBJID":"id-159","SITEID":"CHN-5","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.54626,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-27 04:18:29","TRTEDTM":"2022-05-26 22:18:29","TRT01SDTM":"2019-05-27 04:18:29","TRT01EDTM":"2021-05-26 16:18:29","TRT02SDTM":"2021-05-26 16:18:29","TRT02EDTM":"2022-05-26 22:18:29","AP01SDTM":"2019-05-27 04:18:29","AP01EDTM":"2021-05-26 16:18:29","AP02SDTM":"2021-05-26 16:18:29","AP02EDTM":"2022-05-26 22:18:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-26","EOSDY":1096,"LSTALVDT":"2022-06-11","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7927,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.48232,"AVALU":"mg/L","BASE2":8.30252,"BASE":8.73391,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.17979,"PCHG2":14.21007,"CHG":0.74841,"PCHG":8.56903,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-05 04:18:29","ADY":1074,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-159","SUBJID":"id-159","SITEID":"CHN-5","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.54626,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-27 04:18:29","TRTEDTM":"2022-05-26 22:18:29","TRT01SDTM":"2019-05-27 04:18:29","TRT01EDTM":"2021-05-26 16:18:29","TRT02SDTM":"2021-05-26 16:18:29","TRT02EDTM":"2022-05-26 22:18:29","AP01SDTM":"2019-05-27 04:18:29","AP01EDTM":"2021-05-26 16:18:29","AP02SDTM":"2021-05-26 16:18:29","AP02EDTM":"2022-05-26 22:18:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-26","EOSDY":1096,"LSTALVDT":"2022-06-11","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":644,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89085,"AVALU":"g/L","BASE2":2.89085,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-05-27 04:18:29","ADY":0,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-159","SUBJID":"id-159","SITEID":"CHN-5","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.54626,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-27 04:18:29","TRTEDTM":"2022-05-26 22:18:29","TRT01SDTM":"2019-05-27 04:18:29","TRT01EDTM":"2021-05-26 16:18:29","TRT02SDTM":"2021-05-26 16:18:29","TRT02EDTM":"2022-05-26 22:18:29","AP01SDTM":"2019-05-27 04:18:29","AP01EDTM":"2021-05-26 16:18:29","AP02SDTM":"2021-05-26 16:18:29","AP02EDTM":"2022-05-26 22:18:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-26","EOSDY":1096,"LSTALVDT":"2022-06-11","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1808,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83295,"AVALU":"g/L","BASE2":2.89085,"BASE":2.83295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.0579,"PCHG2":-2.00294,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-09 04:18:29","ADY":227,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-159","SUBJID":"id-159","SITEID":"CHN-5","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.54626,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-27 04:18:29","TRTEDTM":"2022-05-26 22:18:29","TRT01SDTM":"2019-05-27 04:18:29","TRT01EDTM":"2021-05-26 16:18:29","TRT02SDTM":"2021-05-26 16:18:29","TRT02EDTM":"2022-05-26 22:18:29","AP01SDTM":"2019-05-27 04:18:29","AP01EDTM":"2021-05-26 16:18:29","AP02SDTM":"2021-05-26 16:18:29","AP02EDTM":"2022-05-26 22:18:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-26","EOSDY":1096,"LSTALVDT":"2022-06-11","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3854,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97874,"AVALU":"g/L","BASE2":2.89085,"BASE":2.83295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08789,"PCHG2":3.04019,"CHG":0.14579,"PCHG":5.14621,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-11 04:18:29","ADY":260,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-159","SUBJID":"id-159","SITEID":"CHN-5","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.54626,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-27 04:18:29","TRTEDTM":"2022-05-26 22:18:29","TRT01SDTM":"2019-05-27 04:18:29","TRT01EDTM":"2021-05-26 16:18:29","TRT02SDTM":"2021-05-26 16:18:29","TRT02EDTM":"2022-05-26 22:18:29","AP01SDTM":"2019-05-27 04:18:29","AP01EDTM":"2021-05-26 16:18:29","AP02SDTM":"2021-05-26 16:18:29","AP02EDTM":"2022-05-26 22:18:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-26","EOSDY":1096,"LSTALVDT":"2022-06-11","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2071,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.891,"AVALU":"g/L","BASE2":2.89085,"BASE":2.83295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00015,"PCHG2":0.0052,"CHG":0.05805,"PCHG":2.04919,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-01 04:18:29","ADY":401,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-159","SUBJID":"id-159","SITEID":"CHN-5","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.54626,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-27 04:18:29","TRTEDTM":"2022-05-26 22:18:29","TRT01SDTM":"2019-05-27 04:18:29","TRT01EDTM":"2021-05-26 16:18:29","TRT02SDTM":"2021-05-26 16:18:29","TRT02EDTM":"2022-05-26 22:18:29","AP01SDTM":"2019-05-27 04:18:29","AP01EDTM":"2021-05-26 16:18:29","AP02SDTM":"2021-05-26 16:18:29","AP02EDTM":"2022-05-26 22:18:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-26","EOSDY":1096,"LSTALVDT":"2022-06-11","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":180,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97687,"AVALU":"g/L","BASE2":2.89085,"BASE":2.83295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08602,"PCHG2":2.97575,"CHG":0.14393,"PCHG":5.08045,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-05 04:18:29","ADY":497,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-159","SUBJID":"id-159","SITEID":"CHN-5","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.54626,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-27 04:18:29","TRTEDTM":"2022-05-26 22:18:29","TRT01SDTM":"2019-05-27 04:18:29","TRT01EDTM":"2021-05-26 16:18:29","TRT02SDTM":"2021-05-26 16:18:29","TRT02EDTM":"2022-05-26 22:18:29","AP01SDTM":"2019-05-27 04:18:29","AP01EDTM":"2021-05-26 16:18:29","AP02SDTM":"2021-05-26 16:18:29","AP02EDTM":"2022-05-26 22:18:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-26","EOSDY":1096,"LSTALVDT":"2022-06-11","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5402,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04139,"AVALU":"g/L","BASE2":2.89085,"BASE":2.83295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15054,"PCHG2":5.20759,"CHG":0.20845,"PCHG":7.35791,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-02-17 04:18:29","ADY":632,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-159","SUBJID":"id-159","SITEID":"CHN-5","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.54626,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-27 04:18:29","TRTEDTM":"2022-05-26 22:18:29","TRT01SDTM":"2019-05-27 04:18:29","TRT01EDTM":"2021-05-26 16:18:29","TRT02SDTM":"2021-05-26 16:18:29","TRT02EDTM":"2022-05-26 22:18:29","AP01SDTM":"2019-05-27 04:18:29","AP01EDTM":"2021-05-26 16:18:29","AP02SDTM":"2021-05-26 16:18:29","AP02EDTM":"2022-05-26 22:18:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-26","EOSDY":1096,"LSTALVDT":"2022-06-11","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7592,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87959,"AVALU":"g/L","BASE2":2.89085,"BASE":2.83295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01126,"PCHG2":-0.38951,"CHG":0.04664,"PCHG":1.64641,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-05 04:18:29","ADY":1074,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-160","SUBJID":"id-160","SITEID":"CHN-5","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":0.16545,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-17 21:28:31","TRTEDTM":"2022-07-17 15:28:31","TRT01SDTM":"2019-07-17 21:28:31","TRT01EDTM":"2021-07-17 09:28:31","TRT02SDTM":"2021-07-17 09:28:31","TRT02EDTM":"2022-07-17 15:28:31","AP01SDTM":"2019-07-17 21:28:31","AP01EDTM":"2021-07-17 09:28:31","AP02SDTM":"2021-07-17 09:28:31","AP02EDTM":"2022-07-17 15:28:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-27","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":537,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.53253,"AVALU":"U/L","BASE2":19.53253,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-31 21:28:31","ADY":45,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-160","SUBJID":"id-160","SITEID":"CHN-5","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":0.16545,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-17 21:28:31","TRTEDTM":"2022-07-17 15:28:31","TRT01SDTM":"2019-07-17 21:28:31","TRT01EDTM":"2021-07-17 09:28:31","TRT02SDTM":"2021-07-17 09:28:31","TRT02EDTM":"2022-07-17 15:28:31","AP01SDTM":"2019-07-17 21:28:31","AP01EDTM":"2021-07-17 09:28:31","AP02SDTM":"2021-07-17 09:28:31","AP02EDTM":"2022-07-17 15:28:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-27","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3078,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.42991,"AVALU":"U/L","BASE2":19.53253,"BASE":9.42991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-10.10262,"PCHG2":-51.72201,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-14 21:28:31","ADY":89,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-160","SUBJID":"id-160","SITEID":"CHN-5","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":0.16545,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-17 21:28:31","TRTEDTM":"2022-07-17 15:28:31","TRT01SDTM":"2019-07-17 21:28:31","TRT01EDTM":"2021-07-17 09:28:31","TRT02SDTM":"2021-07-17 09:28:31","TRT02EDTM":"2022-07-17 15:28:31","AP01SDTM":"2019-07-17 21:28:31","AP01EDTM":"2021-07-17 09:28:31","AP02SDTM":"2021-07-17 09:28:31","AP02EDTM":"2022-07-17 15:28:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-27","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3828,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.00742,"AVALU":"U/L","BASE2":19.53253,"BASE":9.42991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.47488,"PCHG2":38.26889,"CHG":17.5775,"PCHG":186.40153,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-07 21:28:31","ADY":356,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-160","SUBJID":"id-160","SITEID":"CHN-5","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":0.16545,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-17 21:28:31","TRTEDTM":"2022-07-17 15:28:31","TRT01SDTM":"2019-07-17 21:28:31","TRT01EDTM":"2021-07-17 09:28:31","TRT02SDTM":"2021-07-17 09:28:31","TRT02EDTM":"2022-07-17 15:28:31","AP01SDTM":"2019-07-17 21:28:31","AP01EDTM":"2021-07-17 09:28:31","AP02SDTM":"2021-07-17 09:28:31","AP02EDTM":"2022-07-17 15:28:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-27","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":681,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.67355,"AVALU":"U/L","BASE2":19.53253,"BASE":9.42991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.85898,"PCHG2":-29.99601,"CHG":4.24364,"PCHG":45.00189,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-26 21:28:31","ADY":618,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-160","SUBJID":"id-160","SITEID":"CHN-5","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":0.16545,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-17 21:28:31","TRTEDTM":"2022-07-17 15:28:31","TRT01SDTM":"2019-07-17 21:28:31","TRT01EDTM":"2021-07-17 09:28:31","TRT02SDTM":"2021-07-17 09:28:31","TRT02EDTM":"2022-07-17 15:28:31","AP01SDTM":"2019-07-17 21:28:31","AP01EDTM":"2021-07-17 09:28:31","AP02SDTM":"2021-07-17 09:28:31","AP02EDTM":"2022-07-17 15:28:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-27","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.21701,"AVALU":"U/L","BASE2":19.53253,"BASE":9.42991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.68447,"PCHG2":29.1026,"CHG":15.78709,"PCHG":167.41504,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-04 21:28:31","ADY":657,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-160","SUBJID":"id-160","SITEID":"CHN-5","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":0.16545,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-17 21:28:31","TRTEDTM":"2022-07-17 15:28:31","TRT01SDTM":"2019-07-17 21:28:31","TRT01EDTM":"2021-07-17 09:28:31","TRT02SDTM":"2021-07-17 09:28:31","TRT02EDTM":"2022-07-17 15:28:31","AP01SDTM":"2019-07-17 21:28:31","AP01EDTM":"2021-07-17 09:28:31","AP02SDTM":"2021-07-17 09:28:31","AP02EDTM":"2022-07-17 15:28:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-27","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4804,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.36,"AVALU":"U/L","BASE2":19.53253,"BASE":9.42991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.17253,"PCHG2":-31.60128,"CHG":3.93009,"PCHG":41.67682,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-04 21:28:31","ADY":871,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-160","SUBJID":"id-160","SITEID":"CHN-5","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":0.16545,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-17 21:28:31","TRTEDTM":"2022-07-17 15:28:31","TRT01SDTM":"2019-07-17 21:28:31","TRT01EDTM":"2021-07-17 09:28:31","TRT02SDTM":"2021-07-17 09:28:31","TRT02EDTM":"2022-07-17 15:28:31","AP01SDTM":"2019-07-17 21:28:31","AP01EDTM":"2021-07-17 09:28:31","AP02SDTM":"2021-07-17 09:28:31","AP02EDTM":"2022-07-17 15:28:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-27","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5226,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.21972,"AVALU":"U/L","BASE2":19.53253,"BASE":9.42991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.68719,"PCHG2":18.87717,"CHG":13.78981,"PCHG":146.23473,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-20 21:28:31","ADY":949,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-160","SUBJID":"id-160","SITEID":"CHN-5","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":0.16545,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-17 21:28:31","TRTEDTM":"2022-07-17 15:28:31","TRT01SDTM":"2019-07-17 21:28:31","TRT01EDTM":"2021-07-17 09:28:31","TRT02SDTM":"2021-07-17 09:28:31","TRT02EDTM":"2022-07-17 15:28:31","AP01SDTM":"2019-07-17 21:28:31","AP01EDTM":"2021-07-17 09:28:31","AP02SDTM":"2021-07-17 09:28:31","AP02EDTM":"2022-07-17 15:28:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-27","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5219,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.96645,"AVALU":"mg/L","BASE2":7.96645,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2019-08-31 21:28:31","ADY":45,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-160","SUBJID":"id-160","SITEID":"CHN-5","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":0.16545,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-17 21:28:31","TRTEDTM":"2022-07-17 15:28:31","TRT01SDTM":"2019-07-17 21:28:31","TRT01EDTM":"2021-07-17 09:28:31","TRT02SDTM":"2021-07-17 09:28:31","TRT02EDTM":"2022-07-17 15:28:31","AP01SDTM":"2019-07-17 21:28:31","AP01EDTM":"2021-07-17 09:28:31","AP02SDTM":"2021-07-17 09:28:31","AP02EDTM":"2022-07-17 15:28:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-27","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":717,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.41084,"AVALU":"mg/L","BASE2":7.96645,"BASE":9.41084,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.44438,"PCHG2":18.1308,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-14 21:28:31","ADY":89,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-160","SUBJID":"id-160","SITEID":"CHN-5","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":0.16545,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-17 21:28:31","TRTEDTM":"2022-07-17 15:28:31","TRT01SDTM":"2019-07-17 21:28:31","TRT01EDTM":"2021-07-17 09:28:31","TRT02SDTM":"2021-07-17 09:28:31","TRT02EDTM":"2022-07-17 15:28:31","AP01SDTM":"2019-07-17 21:28:31","AP01EDTM":"2021-07-17 09:28:31","AP02SDTM":"2021-07-17 09:28:31","AP02EDTM":"2022-07-17 15:28:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-27","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4018,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.60565,"AVALU":"mg/L","BASE2":7.96645,"BASE":9.41084,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.3608,"PCHG2":-4.52905,"CHG":-1.80519,"PCHG":-19.182,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-07-07 21:28:31","ADY":356,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-160","SUBJID":"id-160","SITEID":"CHN-5","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":0.16545,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-17 21:28:31","TRTEDTM":"2022-07-17 15:28:31","TRT01SDTM":"2019-07-17 21:28:31","TRT01EDTM":"2021-07-17 09:28:31","TRT02SDTM":"2021-07-17 09:28:31","TRT02EDTM":"2022-07-17 15:28:31","AP01SDTM":"2019-07-17 21:28:31","AP01EDTM":"2021-07-17 09:28:31","AP02SDTM":"2021-07-17 09:28:31","AP02EDTM":"2022-07-17 15:28:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-27","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2119,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.34106,"AVALU":"mg/L","BASE2":7.96645,"BASE":9.41084,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.37461,"PCHG2":4.7023,"CHG":-1.06978,"PCHG":-11.36749,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-26 21:28:31","ADY":618,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-160","SUBJID":"id-160","SITEID":"CHN-5","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":0.16545,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-17 21:28:31","TRTEDTM":"2022-07-17 15:28:31","TRT01SDTM":"2019-07-17 21:28:31","TRT01EDTM":"2021-07-17 09:28:31","TRT02SDTM":"2021-07-17 09:28:31","TRT02EDTM":"2022-07-17 15:28:31","AP01SDTM":"2019-07-17 21:28:31","AP01EDTM":"2021-07-17 09:28:31","AP02SDTM":"2021-07-17 09:28:31","AP02EDTM":"2022-07-17 15:28:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-27","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8197,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.9084,"AVALU":"mg/L","BASE2":7.96645,"BASE":9.41084,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.94195,"PCHG2":11.82395,"CHG":-0.50243,"PCHG":-5.33887,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-04 21:28:31","ADY":657,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-160","SUBJID":"id-160","SITEID":"CHN-5","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":0.16545,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-17 21:28:31","TRTEDTM":"2022-07-17 15:28:31","TRT01SDTM":"2019-07-17 21:28:31","TRT01EDTM":"2021-07-17 09:28:31","TRT02SDTM":"2021-07-17 09:28:31","TRT02EDTM":"2022-07-17 15:28:31","AP01SDTM":"2019-07-17 21:28:31","AP01EDTM":"2021-07-17 09:28:31","AP02SDTM":"2021-07-17 09:28:31","AP02EDTM":"2022-07-17 15:28:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-27","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5650,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.38995,"AVALU":"mg/L","BASE2":7.96645,"BASE":9.41084,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.42349,"PCHG2":17.86856,"CHG":-0.02089,"PCHG":-0.22199,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-04 21:28:31","ADY":871,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-160","SUBJID":"id-160","SITEID":"CHN-5","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":0.16545,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-17 21:28:31","TRTEDTM":"2022-07-17 15:28:31","TRT01SDTM":"2019-07-17 21:28:31","TRT01EDTM":"2021-07-17 09:28:31","TRT02SDTM":"2021-07-17 09:28:31","TRT02EDTM":"2022-07-17 15:28:31","AP01SDTM":"2019-07-17 21:28:31","AP01EDTM":"2021-07-17 09:28:31","AP02SDTM":"2021-07-17 09:28:31","AP02EDTM":"2022-07-17 15:28:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-27","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8117,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.62692,"AVALU":"mg/L","BASE2":7.96645,"BASE":9.41084,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.33953,"PCHG2":-4.26202,"CHG":-1.78391,"PCHG":-18.95595,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2022-02-20 21:28:31","ADY":949,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-160","SUBJID":"id-160","SITEID":"CHN-5","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":0.16545,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-17 21:28:31","TRTEDTM":"2022-07-17 15:28:31","TRT01SDTM":"2019-07-17 21:28:31","TRT01EDTM":"2021-07-17 09:28:31","TRT02SDTM":"2021-07-17 09:28:31","TRT02EDTM":"2022-07-17 15:28:31","AP01SDTM":"2019-07-17 21:28:31","AP01EDTM":"2021-07-17 09:28:31","AP02SDTM":"2021-07-17 09:28:31","AP02EDTM":"2022-07-17 15:28:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-27","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":373,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97069,"AVALU":"g/L","BASE2":2.97069,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-31 21:28:31","ADY":45,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-160","SUBJID":"id-160","SITEID":"CHN-5","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":0.16545,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-17 21:28:31","TRTEDTM":"2022-07-17 15:28:31","TRT01SDTM":"2019-07-17 21:28:31","TRT01EDTM":"2021-07-17 09:28:31","TRT02SDTM":"2021-07-17 09:28:31","TRT02EDTM":"2022-07-17 15:28:31","AP01SDTM":"2019-07-17 21:28:31","AP01EDTM":"2021-07-17 09:28:31","AP02SDTM":"2021-07-17 09:28:31","AP02EDTM":"2022-07-17 15:28:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-27","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5702,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99888,"AVALU":"g/L","BASE2":2.97069,"BASE":2.99888,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.02819,"PCHG2":0.9488,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-14 21:28:31","ADY":89,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-160","SUBJID":"id-160","SITEID":"CHN-5","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":0.16545,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-17 21:28:31","TRTEDTM":"2022-07-17 15:28:31","TRT01SDTM":"2019-07-17 21:28:31","TRT01EDTM":"2021-07-17 09:28:31","TRT02SDTM":"2021-07-17 09:28:31","TRT02EDTM":"2022-07-17 15:28:31","AP01SDTM":"2019-07-17 21:28:31","AP01EDTM":"2021-07-17 09:28:31","AP02SDTM":"2021-07-17 09:28:31","AP02EDTM":"2022-07-17 15:28:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-27","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6618,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97717,"AVALU":"g/L","BASE2":2.97069,"BASE":2.99888,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00647,"PCHG2":0.21794,"CHG":-0.02171,"PCHG":-0.72399,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-07 21:28:31","ADY":356,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-160","SUBJID":"id-160","SITEID":"CHN-5","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":0.16545,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-17 21:28:31","TRTEDTM":"2022-07-17 15:28:31","TRT01SDTM":"2019-07-17 21:28:31","TRT01EDTM":"2021-07-17 09:28:31","TRT02SDTM":"2021-07-17 09:28:31","TRT02EDTM":"2022-07-17 15:28:31","AP01SDTM":"2019-07-17 21:28:31","AP01EDTM":"2021-07-17 09:28:31","AP02SDTM":"2021-07-17 09:28:31","AP02EDTM":"2022-07-17 15:28:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-27","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3234,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95028,"AVALU":"g/L","BASE2":2.97069,"BASE":2.99888,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02041,"PCHG2":-0.6872,"CHG":-0.0486,"PCHG":-1.62062,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-26 21:28:31","ADY":618,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-160","SUBJID":"id-160","SITEID":"CHN-5","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":0.16545,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-17 21:28:31","TRTEDTM":"2022-07-17 15:28:31","TRT01SDTM":"2019-07-17 21:28:31","TRT01EDTM":"2021-07-17 09:28:31","TRT02SDTM":"2021-07-17 09:28:31","TRT02EDTM":"2022-07-17 15:28:31","AP01SDTM":"2019-07-17 21:28:31","AP01EDTM":"2021-07-17 09:28:31","AP02SDTM":"2021-07-17 09:28:31","AP02EDTM":"2022-07-17 15:28:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-27","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6550,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80066,"AVALU":"g/L","BASE2":2.97069,"BASE":2.99888,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17003,"PCHG2":-5.72349,"CHG":-0.19821,"PCHG":-6.60958,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-04 21:28:31","ADY":657,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-160","SUBJID":"id-160","SITEID":"CHN-5","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":0.16545,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-17 21:28:31","TRTEDTM":"2022-07-17 15:28:31","TRT01SDTM":"2019-07-17 21:28:31","TRT01EDTM":"2021-07-17 09:28:31","TRT02SDTM":"2021-07-17 09:28:31","TRT02EDTM":"2022-07-17 15:28:31","AP01SDTM":"2019-07-17 21:28:31","AP01EDTM":"2021-07-17 09:28:31","AP02SDTM":"2021-07-17 09:28:31","AP02EDTM":"2022-07-17 15:28:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-27","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7290,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7506,"AVALU":"g/L","BASE2":2.97069,"BASE":2.99888,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.22009,"PCHG2":-7.40888,"CHG":-0.24828,"PCHG":-8.27913,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-04 21:28:31","ADY":871,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-160","SUBJID":"id-160","SITEID":"CHN-5","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":0.16545,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-15","TRTSDTM":"2019-07-17 21:28:31","TRTEDTM":"2022-07-17 15:28:31","TRT01SDTM":"2019-07-17 21:28:31","TRT01EDTM":"2021-07-17 09:28:31","TRT02SDTM":"2021-07-17 09:28:31","TRT02EDTM":"2022-07-17 15:28:31","AP01SDTM":"2019-07-17 21:28:31","AP01EDTM":"2021-07-17 09:28:31","AP02SDTM":"2021-07-17 09:28:31","AP02EDTM":"2022-07-17 15:28:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-17","EOSDY":1096,"LSTALVDT":"2022-07-27","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4956,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.69494,"AVALU":"g/L","BASE2":2.97069,"BASE":2.99888,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.27575,"PCHG2":-9.2824,"CHG":-0.30394,"PCHG":-10.13504,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-20 21:28:31","ADY":949,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-175","SUBJID":"id-175","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.98017,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-29","TRTSDTM":"2020-10-03 06:43:58","TRTEDTM":"2023-10-04 00:43:58","TRT01SDTM":"2020-10-03 06:43:58","TRT01EDTM":"2022-10-03 18:43:58","TRT02SDTM":"2022-10-03 18:43:58","TRT02EDTM":"2023-10-04 00:43:58","AP01SDTM":"2020-10-03 06:43:58","AP01EDTM":"2022-10-03 18:43:58","AP02SDTM":"2022-10-03 18:43:58","AP02EDTM":"2023-10-04 00:43:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5248,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.8203,"AVALU":"U/L","BASE2":22.8203,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-19 06:43:58","ADY":139,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-175","SUBJID":"id-175","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.98017,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-29","TRTSDTM":"2020-10-03 06:43:58","TRTEDTM":"2023-10-04 00:43:58","TRT01SDTM":"2020-10-03 06:43:58","TRT01EDTM":"2022-10-03 18:43:58","TRT02SDTM":"2022-10-03 18:43:58","TRT02EDTM":"2023-10-04 00:43:58","AP01SDTM":"2020-10-03 06:43:58","AP01EDTM":"2022-10-03 18:43:58","AP02SDTM":"2022-10-03 18:43:58","AP02EDTM":"2023-10-04 00:43:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4723,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.03744,"AVALU":"U/L","BASE2":22.8203,"BASE":10.03744,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-12.78285,"PCHG2":-56.01529,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-26 06:43:58","ADY":146,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-175","SUBJID":"id-175","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.98017,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-29","TRTSDTM":"2020-10-03 06:43:58","TRTEDTM":"2023-10-04 00:43:58","TRT01SDTM":"2020-10-03 06:43:58","TRT01EDTM":"2022-10-03 18:43:58","TRT02SDTM":"2022-10-03 18:43:58","TRT02EDTM":"2023-10-04 00:43:58","AP01SDTM":"2020-10-03 06:43:58","AP01EDTM":"2022-10-03 18:43:58","AP02SDTM":"2022-10-03 18:43:58","AP02EDTM":"2023-10-04 00:43:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3404,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.02264,"AVALU":"U/L","BASE2":22.8203,"BASE":10.03744,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.79765,"PCHG2":-12.2595,"CHG":9.9852,"PCHG":99.47955,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-17 06:43:58","ADY":502,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-175","SUBJID":"id-175","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.98017,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-29","TRTSDTM":"2020-10-03 06:43:58","TRTEDTM":"2023-10-04 00:43:58","TRT01SDTM":"2020-10-03 06:43:58","TRT01EDTM":"2022-10-03 18:43:58","TRT02SDTM":"2022-10-03 18:43:58","TRT02EDTM":"2023-10-04 00:43:58","AP01SDTM":"2020-10-03 06:43:58","AP01EDTM":"2022-10-03 18:43:58","AP02SDTM":"2022-10-03 18:43:58","AP02EDTM":"2023-10-04 00:43:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6276,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.84879,"AVALU":"U/L","BASE2":22.8203,"BASE":10.03744,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.9715,"PCHG2":-26.1675,"CHG":6.81135,"PCHG":67.85947,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-18 06:43:58","ADY":592,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-175","SUBJID":"id-175","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.98017,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-29","TRTSDTM":"2020-10-03 06:43:58","TRTEDTM":"2023-10-04 00:43:58","TRT01SDTM":"2020-10-03 06:43:58","TRT01EDTM":"2022-10-03 18:43:58","TRT02SDTM":"2022-10-03 18:43:58","TRT02EDTM":"2023-10-04 00:43:58","AP01SDTM":"2020-10-03 06:43:58","AP01EDTM":"2022-10-03 18:43:58","AP02SDTM":"2022-10-03 18:43:58","AP02EDTM":"2023-10-04 00:43:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2549,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.09676,"AVALU":"U/L","BASE2":22.8203,"BASE":10.03744,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.72353,"PCHG2":-20.69881,"CHG":8.05932,"PCHG":80.29263,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-26 06:43:58","ADY":692,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-175","SUBJID":"id-175","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.98017,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-29","TRTSDTM":"2020-10-03 06:43:58","TRTEDTM":"2023-10-04 00:43:58","TRT01SDTM":"2020-10-03 06:43:58","TRT01EDTM":"2022-10-03 18:43:58","TRT02SDTM":"2022-10-03 18:43:58","TRT02EDTM":"2023-10-04 00:43:58","AP01SDTM":"2020-10-03 06:43:58","AP01EDTM":"2022-10-03 18:43:58","AP02SDTM":"2022-10-03 18:43:58","AP02EDTM":"2023-10-04 00:43:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4668,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.11182,"AVALU":"U/L","BASE2":22.8203,"BASE":10.03744,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.70848,"PCHG2":-51.30731,"CHG":1.07438,"PCHG":10.70369,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-19 06:43:58","ADY":807,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-175","SUBJID":"id-175","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.98017,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-29","TRTSDTM":"2020-10-03 06:43:58","TRTEDTM":"2023-10-04 00:43:58","TRT01SDTM":"2020-10-03 06:43:58","TRT01EDTM":"2022-10-03 18:43:58","TRT02SDTM":"2022-10-03 18:43:58","TRT02EDTM":"2023-10-04 00:43:58","AP01SDTM":"2020-10-03 06:43:58","AP01EDTM":"2022-10-03 18:43:58","AP02SDTM":"2022-10-03 18:43:58","AP02EDTM":"2023-10-04 00:43:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2920,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.49937,"AVALU":"U/L","BASE2":22.8203,"BASE":10.03744,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.67907,"PCHG2":2.97574,"CHG":13.46193,"PCHG":134.11714,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-27 06:43:58","ADY":936,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-175","SUBJID":"id-175","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.98017,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-29","TRTSDTM":"2020-10-03 06:43:58","TRTEDTM":"2023-10-04 00:43:58","TRT01SDTM":"2020-10-03 06:43:58","TRT01EDTM":"2022-10-03 18:43:58","TRT02SDTM":"2022-10-03 18:43:58","TRT02EDTM":"2023-10-04 00:43:58","AP01SDTM":"2020-10-03 06:43:58","AP01EDTM":"2022-10-03 18:43:58","AP02SDTM":"2022-10-03 18:43:58","AP02EDTM":"2023-10-04 00:43:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8242,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.72984,"AVALU":"mg/L","BASE2":8.72984,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-02-19 06:43:58","ADY":139,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-175","SUBJID":"id-175","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.98017,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-29","TRTSDTM":"2020-10-03 06:43:58","TRTEDTM":"2023-10-04 00:43:58","TRT01SDTM":"2020-10-03 06:43:58","TRT01EDTM":"2022-10-03 18:43:58","TRT02SDTM":"2022-10-03 18:43:58","TRT02EDTM":"2023-10-04 00:43:58","AP01SDTM":"2020-10-03 06:43:58","AP01EDTM":"2022-10-03 18:43:58","AP02SDTM":"2022-10-03 18:43:58","AP02EDTM":"2023-10-04 00:43:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3827,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.93283,"AVALU":"mg/L","BASE2":8.72984,"BASE":7.93283,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.79702,"PCHG2":-9.12978,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2021-02-26 06:43:58","ADY":146,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-175","SUBJID":"id-175","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.98017,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-29","TRTSDTM":"2020-10-03 06:43:58","TRTEDTM":"2023-10-04 00:43:58","TRT01SDTM":"2020-10-03 06:43:58","TRT01EDTM":"2022-10-03 18:43:58","TRT02SDTM":"2022-10-03 18:43:58","TRT02EDTM":"2023-10-04 00:43:58","AP01SDTM":"2020-10-03 06:43:58","AP01EDTM":"2022-10-03 18:43:58","AP02SDTM":"2022-10-03 18:43:58","AP02EDTM":"2023-10-04 00:43:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":70,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.46972,"AVALU":"mg/L","BASE2":8.72984,"BASE":7.93283,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.26013,"PCHG2":-2.97974,"CHG":0.53689,"PCHG":6.76794,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-02-17 06:43:58","ADY":502,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-175","SUBJID":"id-175","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.98017,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-29","TRTSDTM":"2020-10-03 06:43:58","TRTEDTM":"2023-10-04 00:43:58","TRT01SDTM":"2020-10-03 06:43:58","TRT01EDTM":"2022-10-03 18:43:58","TRT02SDTM":"2022-10-03 18:43:58","TRT02EDTM":"2023-10-04 00:43:58","AP01SDTM":"2020-10-03 06:43:58","AP01EDTM":"2022-10-03 18:43:58","AP02SDTM":"2022-10-03 18:43:58","AP02EDTM":"2023-10-04 00:43:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7188,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.57121,"AVALU":"mg/L","BASE2":8.72984,"BASE":7.93283,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15864,"PCHG2":-1.81718,"CHG":0.63838,"PCHG":8.0473,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-05-18 06:43:58","ADY":592,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-175","SUBJID":"id-175","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.98017,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-29","TRTSDTM":"2020-10-03 06:43:58","TRTEDTM":"2023-10-04 00:43:58","TRT01SDTM":"2020-10-03 06:43:58","TRT01EDTM":"2022-10-03 18:43:58","TRT02SDTM":"2022-10-03 18:43:58","TRT02EDTM":"2023-10-04 00:43:58","AP01SDTM":"2020-10-03 06:43:58","AP01EDTM":"2022-10-03 18:43:58","AP02SDTM":"2022-10-03 18:43:58","AP02EDTM":"2023-10-04 00:43:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2180,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.77482,"AVALU":"mg/L","BASE2":8.72984,"BASE":7.93283,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.04498,"PCHG2":11.97015,"CHG":1.84199,"PCHG":23.21986,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-08-26 06:43:58","ADY":692,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-175","SUBJID":"id-175","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.98017,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-29","TRTSDTM":"2020-10-03 06:43:58","TRTEDTM":"2023-10-04 00:43:58","TRT01SDTM":"2020-10-03 06:43:58","TRT01EDTM":"2022-10-03 18:43:58","TRT02SDTM":"2022-10-03 18:43:58","TRT02EDTM":"2023-10-04 00:43:58","AP01SDTM":"2020-10-03 06:43:58","AP01EDTM":"2022-10-03 18:43:58","AP02SDTM":"2022-10-03 18:43:58","AP02EDTM":"2023-10-04 00:43:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4797,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.26626,"AVALU":"mg/L","BASE2":8.72984,"BASE":7.93283,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.53641,"PCHG2":6.14461,"CHG":1.33343,"PCHG":16.80902,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-12-19 06:43:58","ADY":807,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-175","SUBJID":"id-175","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.98017,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-29","TRTSDTM":"2020-10-03 06:43:58","TRTEDTM":"2023-10-04 00:43:58","TRT01SDTM":"2020-10-03 06:43:58","TRT01EDTM":"2022-10-03 18:43:58","TRT02SDTM":"2022-10-03 18:43:58","TRT02EDTM":"2023-10-04 00:43:58","AP01SDTM":"2020-10-03 06:43:58","AP01EDTM":"2022-10-03 18:43:58","AP02SDTM":"2022-10-03 18:43:58","AP02EDTM":"2023-10-04 00:43:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7089,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.01852,"AVALU":"mg/L","BASE2":8.72984,"BASE":7.93283,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.28868,"PCHG2":3.30676,"CHG":1.08569,"PCHG":13.68605,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2023-04-27 06:43:58","ADY":936,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-175","SUBJID":"id-175","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.98017,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-29","TRTSDTM":"2020-10-03 06:43:58","TRTEDTM":"2023-10-04 00:43:58","TRT01SDTM":"2020-10-03 06:43:58","TRT01EDTM":"2022-10-03 18:43:58","TRT02SDTM":"2022-10-03 18:43:58","TRT02EDTM":"2023-10-04 00:43:58","AP01SDTM":"2020-10-03 06:43:58","AP01EDTM":"2022-10-03 18:43:58","AP02SDTM":"2022-10-03 18:43:58","AP02EDTM":"2023-10-04 00:43:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4085,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78994,"AVALU":"g/L","BASE2":2.78994,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-19 06:43:58","ADY":139,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-175","SUBJID":"id-175","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.98017,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-29","TRTSDTM":"2020-10-03 06:43:58","TRTEDTM":"2023-10-04 00:43:58","TRT01SDTM":"2020-10-03 06:43:58","TRT01EDTM":"2022-10-03 18:43:58","TRT02SDTM":"2022-10-03 18:43:58","TRT02EDTM":"2023-10-04 00:43:58","AP01SDTM":"2020-10-03 06:43:58","AP01EDTM":"2022-10-03 18:43:58","AP02SDTM":"2022-10-03 18:43:58","AP02EDTM":"2023-10-04 00:43:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2383,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88911,"AVALU":"g/L","BASE2":2.78994,"BASE":2.88911,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.09917,"PCHG2":3.5544,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-26 06:43:58","ADY":146,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-175","SUBJID":"id-175","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.98017,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-29","TRTSDTM":"2020-10-03 06:43:58","TRTEDTM":"2023-10-04 00:43:58","TRT01SDTM":"2020-10-03 06:43:58","TRT01EDTM":"2022-10-03 18:43:58","TRT02SDTM":"2022-10-03 18:43:58","TRT02EDTM":"2023-10-04 00:43:58","AP01SDTM":"2020-10-03 06:43:58","AP01EDTM":"2022-10-03 18:43:58","AP02SDTM":"2022-10-03 18:43:58","AP02EDTM":"2023-10-04 00:43:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":71,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82242,"AVALU":"g/L","BASE2":2.78994,"BASE":2.88911,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03247,"PCHG2":1.16399,"CHG":-0.06669,"PCHG":-2.30836,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-17 06:43:58","ADY":502,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-175","SUBJID":"id-175","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.98017,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-29","TRTSDTM":"2020-10-03 06:43:58","TRTEDTM":"2023-10-04 00:43:58","TRT01SDTM":"2020-10-03 06:43:58","TRT01EDTM":"2022-10-03 18:43:58","TRT02SDTM":"2022-10-03 18:43:58","TRT02EDTM":"2023-10-04 00:43:58","AP01SDTM":"2020-10-03 06:43:58","AP01EDTM":"2022-10-03 18:43:58","AP02SDTM":"2022-10-03 18:43:58","AP02EDTM":"2023-10-04 00:43:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1807,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96228,"AVALU":"g/L","BASE2":2.78994,"BASE":2.88911,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17234,"PCHG2":6.17729,"CHG":0.07318,"PCHG":2.53286,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-18 06:43:58","ADY":592,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-175","SUBJID":"id-175","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.98017,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-29","TRTSDTM":"2020-10-03 06:43:58","TRTEDTM":"2023-10-04 00:43:58","TRT01SDTM":"2020-10-03 06:43:58","TRT01EDTM":"2022-10-03 18:43:58","TRT02SDTM":"2022-10-03 18:43:58","TRT02EDTM":"2023-10-04 00:43:58","AP01SDTM":"2020-10-03 06:43:58","AP01EDTM":"2022-10-03 18:43:58","AP02SDTM":"2022-10-03 18:43:58","AP02EDTM":"2023-10-04 00:43:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":75,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89075,"AVALU":"g/L","BASE2":2.78994,"BASE":2.88911,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10081,"PCHG2":3.61322,"CHG":0.00164,"PCHG":0.0568,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-26 06:43:58","ADY":692,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-175","SUBJID":"id-175","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.98017,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-29","TRTSDTM":"2020-10-03 06:43:58","TRTEDTM":"2023-10-04 00:43:58","TRT01SDTM":"2020-10-03 06:43:58","TRT01EDTM":"2022-10-03 18:43:58","TRT02SDTM":"2022-10-03 18:43:58","TRT02EDTM":"2023-10-04 00:43:58","AP01SDTM":"2020-10-03 06:43:58","AP01EDTM":"2022-10-03 18:43:58","AP02SDTM":"2022-10-03 18:43:58","AP02EDTM":"2023-10-04 00:43:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6842,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87773,"AVALU":"g/L","BASE2":2.78994,"BASE":2.88911,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08779,"PCHG2":3.14657,"CHG":-0.01138,"PCHG":-0.39384,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-19 06:43:58","ADY":807,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-175","SUBJID":"id-175","SITEID":"CHN-5","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":4.98017,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-29","TRTSDTM":"2020-10-03 06:43:58","TRTEDTM":"2023-10-04 00:43:58","TRT01SDTM":"2020-10-03 06:43:58","TRT01EDTM":"2022-10-03 18:43:58","TRT02SDTM":"2022-10-03 18:43:58","TRT02EDTM":"2023-10-04 00:43:58","AP01SDTM":"2020-10-03 06:43:58","AP01EDTM":"2022-10-03 18:43:58","AP02SDTM":"2022-10-03 18:43:58","AP02EDTM":"2023-10-04 00:43:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-04","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":548,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9629,"AVALU":"g/L","BASE2":2.78994,"BASE":2.88911,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17295,"PCHG2":6.19922,"CHG":0.07379,"PCHG":2.55404,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-27 06:43:58","ADY":936,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-195","SUBJID":"id-195","SITEID":"CHN-5","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.79756,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-03 05:58:06","TRTEDTM":"2023-03-03 23:58:06","TRT01SDTM":"2020-03-03 05:58:06","TRT01EDTM":"2022-03-03 17:58:06","TRT02SDTM":"2022-03-03 17:58:06","TRT02EDTM":"2023-03-03 23:58:06","AP01SDTM":"2020-03-03 05:58:06","AP01EDTM":"2022-03-03 17:58:06","AP02SDTM":"2022-03-03 17:58:06","AP02EDTM":"2023-03-03 23:58:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":804,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.20695,"AVALU":"U/L","BASE2":22.20695,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-04 05:58:06","ADY":62,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-195","SUBJID":"id-195","SITEID":"CHN-5","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.79756,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-03 05:58:06","TRTEDTM":"2023-03-03 23:58:06","TRT01SDTM":"2020-03-03 05:58:06","TRT01EDTM":"2022-03-03 17:58:06","TRT02SDTM":"2022-03-03 17:58:06","TRT02EDTM":"2023-03-03 23:58:06","AP01SDTM":"2020-03-03 05:58:06","AP01EDTM":"2022-03-03 17:58:06","AP02SDTM":"2022-03-03 17:58:06","AP02EDTM":"2023-03-03 23:58:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2902,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.22832,"AVALU":"U/L","BASE2":22.20695,"BASE":19.22832,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.97863,"PCHG2":-13.41306,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-04 05:58:06","ADY":123,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-195","SUBJID":"id-195","SITEID":"CHN-5","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.79756,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-03 05:58:06","TRTEDTM":"2023-03-03 23:58:06","TRT01SDTM":"2020-03-03 05:58:06","TRT01EDTM":"2022-03-03 17:58:06","TRT02SDTM":"2022-03-03 17:58:06","TRT02EDTM":"2023-03-03 23:58:06","AP01SDTM":"2020-03-03 05:58:06","AP01EDTM":"2022-03-03 17:58:06","AP02SDTM":"2022-03-03 17:58:06","AP02EDTM":"2023-03-03 23:58:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6314,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.41762,"AVALU":"U/L","BASE2":22.20695,"BASE":19.22832,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.78933,"PCHG2":-39.57917,"CHG":-5.8107,"PCHG":-30.21947,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-17 05:58:06","ADY":410,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-195","SUBJID":"id-195","SITEID":"CHN-5","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.79756,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-03 05:58:06","TRTEDTM":"2023-03-03 23:58:06","TRT01SDTM":"2020-03-03 05:58:06","TRT01EDTM":"2022-03-03 17:58:06","TRT02SDTM":"2022-03-03 17:58:06","TRT02EDTM":"2023-03-03 23:58:06","AP01SDTM":"2020-03-03 05:58:06","AP01EDTM":"2022-03-03 17:58:06","AP02SDTM":"2022-03-03 17:58:06","AP02EDTM":"2023-03-03 23:58:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2709,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.26525,"AVALU":"U/L","BASE2":22.20695,"BASE":19.22832,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.0583,"PCHG2":18.27492,"CHG":7.03693,"PCHG":36.59671,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-19 05:58:06","ADY":412,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-195","SUBJID":"id-195","SITEID":"CHN-5","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.79756,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-03 05:58:06","TRTEDTM":"2023-03-03 23:58:06","TRT01SDTM":"2020-03-03 05:58:06","TRT01EDTM":"2022-03-03 17:58:06","TRT02SDTM":"2022-03-03 17:58:06","TRT02EDTM":"2023-03-03 23:58:06","AP01SDTM":"2020-03-03 05:58:06","AP01EDTM":"2022-03-03 17:58:06","AP02SDTM":"2022-03-03 17:58:06","AP02EDTM":"2023-03-03 23:58:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6099,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.14539,"AVALU":"U/L","BASE2":22.20695,"BASE":19.22832,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.06155,"PCHG2":-13.78647,"CHG":-0.08292,"PCHG":-0.43126,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-07 05:58:06","ADY":522,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-195","SUBJID":"id-195","SITEID":"CHN-5","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.79756,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-03 05:58:06","TRTEDTM":"2023-03-03 23:58:06","TRT01SDTM":"2020-03-03 05:58:06","TRT01EDTM":"2022-03-03 17:58:06","TRT02SDTM":"2022-03-03 17:58:06","TRT02EDTM":"2023-03-03 23:58:06","AP01SDTM":"2020-03-03 05:58:06","AP01EDTM":"2022-03-03 17:58:06","AP02SDTM":"2022-03-03 17:58:06","AP02EDTM":"2023-03-03 23:58:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7846,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":45.86193,"AVALU":"U/L","BASE2":22.20695,"BASE":19.22832,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":23.65498,"PCHG2":106.52065,"CHG":26.63361,"PCHG":138.51246,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-05 05:58:06","ADY":581,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-195","SUBJID":"id-195","SITEID":"CHN-5","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.79756,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-03 05:58:06","TRTEDTM":"2023-03-03 23:58:06","TRT01SDTM":"2020-03-03 05:58:06","TRT01EDTM":"2022-03-03 17:58:06","TRT02SDTM":"2022-03-03 17:58:06","TRT02EDTM":"2023-03-03 23:58:06","AP01SDTM":"2020-03-03 05:58:06","AP01EDTM":"2022-03-03 17:58:06","AP02SDTM":"2022-03-03 17:58:06","AP02EDTM":"2023-03-03 23:58:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2628,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.83644,"AVALU":"U/L","BASE2":22.20695,"BASE":19.22832,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.6295,"PCHG2":25.35016,"CHG":8.60813,"PCHG":44.76797,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-09 05:58:06","ADY":889,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-195","SUBJID":"id-195","SITEID":"CHN-5","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.79756,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-03 05:58:06","TRTEDTM":"2023-03-03 23:58:06","TRT01SDTM":"2020-03-03 05:58:06","TRT01EDTM":"2022-03-03 17:58:06","TRT02SDTM":"2022-03-03 17:58:06","TRT02EDTM":"2023-03-03 23:58:06","AP01SDTM":"2020-03-03 05:58:06","AP01EDTM":"2022-03-03 17:58:06","AP02SDTM":"2022-03-03 17:58:06","AP02EDTM":"2023-03-03 23:58:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2330,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.94763,"AVALU":"mg/L","BASE2":9.94763,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-04 05:58:06","ADY":62,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-195","SUBJID":"id-195","SITEID":"CHN-5","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.79756,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-03 05:58:06","TRTEDTM":"2023-03-03 23:58:06","TRT01SDTM":"2020-03-03 05:58:06","TRT01EDTM":"2022-03-03 17:58:06","TRT02SDTM":"2022-03-03 17:58:06","TRT02EDTM":"2023-03-03 23:58:06","AP01SDTM":"2020-03-03 05:58:06","AP01EDTM":"2022-03-03 17:58:06","AP02SDTM":"2022-03-03 17:58:06","AP02EDTM":"2023-03-03 23:58:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6797,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.72061,"AVALU":"mg/L","BASE2":9.94763,"BASE":8.72061,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.22702,"PCHG2":-12.33479,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-04 05:58:06","ADY":123,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-195","SUBJID":"id-195","SITEID":"CHN-5","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.79756,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-03 05:58:06","TRTEDTM":"2023-03-03 23:58:06","TRT01SDTM":"2020-03-03 05:58:06","TRT01EDTM":"2022-03-03 17:58:06","TRT02SDTM":"2022-03-03 17:58:06","TRT02EDTM":"2023-03-03 23:58:06","AP01SDTM":"2020-03-03 05:58:06","AP01EDTM":"2022-03-03 17:58:06","AP02SDTM":"2022-03-03 17:58:06","AP02EDTM":"2023-03-03 23:58:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3039,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.4372,"AVALU":"mg/L","BASE2":9.94763,"BASE":8.72061,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.51043,"PCHG2":-15.1838,"CHG":-0.28341,"PCHG":-3.24987,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-17 05:58:06","ADY":410,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-195","SUBJID":"id-195","SITEID":"CHN-5","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.79756,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-03 05:58:06","TRTEDTM":"2023-03-03 23:58:06","TRT01SDTM":"2020-03-03 05:58:06","TRT01EDTM":"2022-03-03 17:58:06","TRT02SDTM":"2022-03-03 17:58:06","TRT02EDTM":"2023-03-03 23:58:06","AP01SDTM":"2020-03-03 05:58:06","AP01EDTM":"2022-03-03 17:58:06","AP02SDTM":"2022-03-03 17:58:06","AP02EDTM":"2023-03-03 23:58:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7254,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.73767,"AVALU":"mg/L","BASE2":9.94763,"BASE":8.72061,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20996,"PCHG2":-2.11064,"CHG":1.01706,"PCHG":11.66273,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-19 05:58:06","ADY":412,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-195","SUBJID":"id-195","SITEID":"CHN-5","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.79756,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-03 05:58:06","TRTEDTM":"2023-03-03 23:58:06","TRT01SDTM":"2020-03-03 05:58:06","TRT01EDTM":"2022-03-03 17:58:06","TRT02SDTM":"2022-03-03 17:58:06","TRT02EDTM":"2023-03-03 23:58:06","AP01SDTM":"2020-03-03 05:58:06","AP01EDTM":"2022-03-03 17:58:06","AP02SDTM":"2022-03-03 17:58:06","AP02EDTM":"2023-03-03 23:58:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1196,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.84542,"AVALU":"mg/L","BASE2":9.94763,"BASE":8.72061,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10221,"PCHG2":-1.0275,"CHG":1.12481,"PCHG":12.89827,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-07 05:58:06","ADY":522,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-195","SUBJID":"id-195","SITEID":"CHN-5","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.79756,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-03 05:58:06","TRTEDTM":"2023-03-03 23:58:06","TRT01SDTM":"2020-03-03 05:58:06","TRT01EDTM":"2022-03-03 17:58:06","TRT02SDTM":"2022-03-03 17:58:06","TRT02EDTM":"2023-03-03 23:58:06","AP01SDTM":"2020-03-03 05:58:06","AP01EDTM":"2022-03-03 17:58:06","AP02SDTM":"2022-03-03 17:58:06","AP02EDTM":"2023-03-03 23:58:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3562,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.68363,"AVALU":"mg/L","BASE2":9.94763,"BASE":8.72061,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.736,"PCHG2":7.39871,"CHG":1.96302,"PCHG":22.51008,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2021-10-05 05:58:06","ADY":581,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-195","SUBJID":"id-195","SITEID":"CHN-5","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.79756,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-03 05:58:06","TRTEDTM":"2023-03-03 23:58:06","TRT01SDTM":"2020-03-03 05:58:06","TRT01EDTM":"2022-03-03 17:58:06","TRT02SDTM":"2022-03-03 17:58:06","TRT02EDTM":"2023-03-03 23:58:06","AP01SDTM":"2020-03-03 05:58:06","AP01EDTM":"2022-03-03 17:58:06","AP02SDTM":"2022-03-03 17:58:06","AP02EDTM":"2023-03-03 23:58:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":686,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.75046,"AVALU":"mg/L","BASE2":9.94763,"BASE":8.72061,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.19717,"PCHG2":-12.0347,"CHG":0.02985,"PCHG":0.34231,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-09 05:58:06","ADY":889,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-195","SUBJID":"id-195","SITEID":"CHN-5","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.79756,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-03 05:58:06","TRTEDTM":"2023-03-03 23:58:06","TRT01SDTM":"2020-03-03 05:58:06","TRT01EDTM":"2022-03-03 17:58:06","TRT02SDTM":"2022-03-03 17:58:06","TRT02EDTM":"2023-03-03 23:58:06","AP01SDTM":"2020-03-03 05:58:06","AP01EDTM":"2022-03-03 17:58:06","AP02SDTM":"2022-03-03 17:58:06","AP02EDTM":"2023-03-03 23:58:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7775,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80618,"AVALU":"g/L","BASE2":2.80618,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-04 05:58:06","ADY":62,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-195","SUBJID":"id-195","SITEID":"CHN-5","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.79756,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-03 05:58:06","TRTEDTM":"2023-03-03 23:58:06","TRT01SDTM":"2020-03-03 05:58:06","TRT01EDTM":"2022-03-03 17:58:06","TRT02SDTM":"2022-03-03 17:58:06","TRT02EDTM":"2023-03-03 23:58:06","AP01SDTM":"2020-03-03 05:58:06","AP01EDTM":"2022-03-03 17:58:06","AP02SDTM":"2022-03-03 17:58:06","AP02EDTM":"2023-03-03 23:58:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3882,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84021,"AVALU":"g/L","BASE2":2.80618,"BASE":2.84021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.03403,"PCHG2":1.2126,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-04 05:58:06","ADY":123,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-195","SUBJID":"id-195","SITEID":"CHN-5","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.79756,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-03 05:58:06","TRTEDTM":"2023-03-03 23:58:06","TRT01SDTM":"2020-03-03 05:58:06","TRT01EDTM":"2022-03-03 17:58:06","TRT02SDTM":"2022-03-03 17:58:06","TRT02EDTM":"2023-03-03 23:58:06","AP01SDTM":"2020-03-03 05:58:06","AP01EDTM":"2022-03-03 17:58:06","AP02SDTM":"2022-03-03 17:58:06","AP02EDTM":"2023-03-03 23:58:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3852,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98298,"AVALU":"g/L","BASE2":2.80618,"BASE":2.84021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1768,"PCHG2":6.30031,"CHG":0.14277,"PCHG":5.02675,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-17 05:58:06","ADY":410,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-195","SUBJID":"id-195","SITEID":"CHN-5","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.79756,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-03 05:58:06","TRTEDTM":"2023-03-03 23:58:06","TRT01SDTM":"2020-03-03 05:58:06","TRT01EDTM":"2022-03-03 17:58:06","TRT02SDTM":"2022-03-03 17:58:06","TRT02EDTM":"2023-03-03 23:58:06","AP01SDTM":"2020-03-03 05:58:06","AP01EDTM":"2022-03-03 17:58:06","AP02SDTM":"2022-03-03 17:58:06","AP02EDTM":"2023-03-03 23:58:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5377,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04788,"AVALU":"g/L","BASE2":2.80618,"BASE":2.84021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.24169,"PCHG2":8.61289,"CHG":0.20767,"PCHG":7.31163,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-04-19 05:58:06","ADY":412,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-195","SUBJID":"id-195","SITEID":"CHN-5","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.79756,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-03 05:58:06","TRTEDTM":"2023-03-03 23:58:06","TRT01SDTM":"2020-03-03 05:58:06","TRT01EDTM":"2022-03-03 17:58:06","TRT02SDTM":"2022-03-03 17:58:06","TRT02EDTM":"2023-03-03 23:58:06","AP01SDTM":"2020-03-03 05:58:06","AP01EDTM":"2022-03-03 17:58:06","AP02SDTM":"2022-03-03 17:58:06","AP02EDTM":"2023-03-03 23:58:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3626,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93885,"AVALU":"g/L","BASE2":2.80618,"BASE":2.84021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13267,"PCHG2":4.7276,"CHG":0.09864,"PCHG":3.47289,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-07 05:58:06","ADY":522,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-195","SUBJID":"id-195","SITEID":"CHN-5","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.79756,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-03 05:58:06","TRTEDTM":"2023-03-03 23:58:06","TRT01SDTM":"2020-03-03 05:58:06","TRT01EDTM":"2022-03-03 17:58:06","TRT02SDTM":"2022-03-03 17:58:06","TRT02EDTM":"2023-03-03 23:58:06","AP01SDTM":"2020-03-03 05:58:06","AP01EDTM":"2022-03-03 17:58:06","AP02SDTM":"2022-03-03 17:58:06","AP02EDTM":"2023-03-03 23:58:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5074,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95876,"AVALU":"g/L","BASE2":2.80618,"BASE":2.84021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15258,"PCHG2":5.43729,"CHG":0.11855,"PCHG":4.17407,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-05 05:58:06","ADY":581,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-195","SUBJID":"id-195","SITEID":"CHN-5","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":1.79756,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-03 05:58:06","TRTEDTM":"2023-03-03 23:58:06","TRT01SDTM":"2020-03-03 05:58:06","TRT01EDTM":"2022-03-03 17:58:06","TRT02SDTM":"2022-03-03 17:58:06","TRT02EDTM":"2023-03-03 23:58:06","AP01SDTM":"2020-03-03 05:58:06","AP01EDTM":"2022-03-03 17:58:06","AP02SDTM":"2022-03-03 17:58:06","AP02EDTM":"2023-03-03 23:58:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":20,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97624,"AVALU":"g/L","BASE2":2.80618,"BASE":2.84021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17005,"PCHG2":6.05996,"CHG":0.13603,"PCHG":4.78929,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-09 05:58:06","ADY":889,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-221","SUBJID":"id-221","SITEID":"CHN-5","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.47576,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-24","TRTSDTM":"2020-10-28 20:35:29","TRTEDTM":"2023-10-29 14:35:29","TRT01SDTM":"2020-10-28 20:35:29","TRT01EDTM":"2022-10-29 08:35:29","TRT02SDTM":"2022-10-29 08:35:29","TRT02EDTM":"2023-10-29 14:35:29","AP01SDTM":"2020-10-28 20:35:29","AP01EDTM":"2022-10-29 08:35:29","AP02SDTM":"2022-10-29 08:35:29","AP02EDTM":"2023-10-29 14:35:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-29","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7497,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.46586,"AVALU":"U/L","BASE2":27.46586,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-07 20:35:29","ADY":102,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-221","SUBJID":"id-221","SITEID":"CHN-5","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.47576,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-24","TRTSDTM":"2020-10-28 20:35:29","TRTEDTM":"2023-10-29 14:35:29","TRT01SDTM":"2020-10-28 20:35:29","TRT01EDTM":"2022-10-29 08:35:29","TRT02SDTM":"2022-10-29 08:35:29","TRT02EDTM":"2023-10-29 14:35:29","AP01SDTM":"2020-10-28 20:35:29","AP01EDTM":"2022-10-29 08:35:29","AP02SDTM":"2022-10-29 08:35:29","AP02EDTM":"2023-10-29 14:35:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-29","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1516,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.75141,"AVALU":"U/L","BASE2":27.46586,"BASE":15.75141,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-11.71445,"PCHG2":-42.65094,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-13 20:35:29","ADY":197,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-221","SUBJID":"id-221","SITEID":"CHN-5","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.47576,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-24","TRTSDTM":"2020-10-28 20:35:29","TRTEDTM":"2023-10-29 14:35:29","TRT01SDTM":"2020-10-28 20:35:29","TRT01EDTM":"2022-10-29 08:35:29","TRT02SDTM":"2022-10-29 08:35:29","TRT02EDTM":"2023-10-29 14:35:29","AP01SDTM":"2020-10-28 20:35:29","AP01EDTM":"2022-10-29 08:35:29","AP02SDTM":"2022-10-29 08:35:29","AP02EDTM":"2023-10-29 14:35:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-29","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.80627,"AVALU":"U/L","BASE2":27.46586,"BASE":15.75141,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.65959,"PCHG2":-35.16945,"CHG":2.05486,"PCHG":13.04553,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-15 20:35:29","ADY":383,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-221","SUBJID":"id-221","SITEID":"CHN-5","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.47576,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-24","TRTSDTM":"2020-10-28 20:35:29","TRTEDTM":"2023-10-29 14:35:29","TRT01SDTM":"2020-10-28 20:35:29","TRT01EDTM":"2022-10-29 08:35:29","TRT02SDTM":"2022-10-29 08:35:29","TRT02EDTM":"2023-10-29 14:35:29","AP01SDTM":"2020-10-28 20:35:29","AP01EDTM":"2022-10-29 08:35:29","AP02SDTM":"2022-10-29 08:35:29","AP02EDTM":"2023-10-29 14:35:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-29","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3230,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.19647,"AVALU":"U/L","BASE2":27.46586,"BASE":15.75141,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.26938,"PCHG2":-30.10786,"CHG":3.44506,"PCHG":21.87147,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-04 20:35:29","ADY":553,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-221","SUBJID":"id-221","SITEID":"CHN-5","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.47576,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-24","TRTSDTM":"2020-10-28 20:35:29","TRTEDTM":"2023-10-29 14:35:29","TRT01SDTM":"2020-10-28 20:35:29","TRT01EDTM":"2022-10-29 08:35:29","TRT02SDTM":"2022-10-29 08:35:29","TRT02EDTM":"2023-10-29 14:35:29","AP01SDTM":"2020-10-28 20:35:29","AP01EDTM":"2022-10-29 08:35:29","AP02SDTM":"2022-10-29 08:35:29","AP02EDTM":"2023-10-29 14:35:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-29","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2651,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.31843,"AVALU":"U/L","BASE2":27.46586,"BASE":15.75141,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-26.14743,"PCHG2":-95.19975,"CHG":-14.43298,"PCHG":-91.62976,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2022-05-13 20:35:29","ADY":562,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-221","SUBJID":"id-221","SITEID":"CHN-5","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.47576,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-24","TRTSDTM":"2020-10-28 20:35:29","TRTEDTM":"2023-10-29 14:35:29","TRT01SDTM":"2020-10-28 20:35:29","TRT01EDTM":"2022-10-29 08:35:29","TRT02SDTM":"2022-10-29 08:35:29","TRT02EDTM":"2023-10-29 14:35:29","AP01SDTM":"2020-10-28 20:35:29","AP01EDTM":"2022-10-29 08:35:29","AP02SDTM":"2022-10-29 08:35:29","AP02EDTM":"2023-10-29 14:35:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-29","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7443,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.41285,"AVALU":"U/L","BASE2":27.46586,"BASE":15.75141,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.053,"PCHG2":-18.3974,"CHG":6.66144,"PCHG":42.29109,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-15 20:35:29","ADY":656,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-221","SUBJID":"id-221","SITEID":"CHN-5","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.47576,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-24","TRTSDTM":"2020-10-28 20:35:29","TRTEDTM":"2023-10-29 14:35:29","TRT01SDTM":"2020-10-28 20:35:29","TRT01EDTM":"2022-10-29 08:35:29","TRT02SDTM":"2022-10-29 08:35:29","TRT02EDTM":"2023-10-29 14:35:29","AP01SDTM":"2020-10-28 20:35:29","AP01EDTM":"2022-10-29 08:35:29","AP02SDTM":"2022-10-29 08:35:29","AP02EDTM":"2023-10-29 14:35:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-29","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5095,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.49996,"AVALU":"U/L","BASE2":27.46586,"BASE":15.75141,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.9659,"PCHG2":-25.36203,"CHG":4.74855,"PCHG":30.14681,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-12 20:35:29","ADY":896,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-221","SUBJID":"id-221","SITEID":"CHN-5","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.47576,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-24","TRTSDTM":"2020-10-28 20:35:29","TRTEDTM":"2023-10-29 14:35:29","TRT01SDTM":"2020-10-28 20:35:29","TRT01EDTM":"2022-10-29 08:35:29","TRT02SDTM":"2022-10-29 08:35:29","TRT02EDTM":"2023-10-29 14:35:29","AP01SDTM":"2020-10-28 20:35:29","AP01EDTM":"2022-10-29 08:35:29","AP02SDTM":"2022-10-29 08:35:29","AP02EDTM":"2023-10-29 14:35:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-29","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4197,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.51004,"AVALU":"mg/L","BASE2":9.51004,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-02-07 20:35:29","ADY":102,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-221","SUBJID":"id-221","SITEID":"CHN-5","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.47576,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-24","TRTSDTM":"2020-10-28 20:35:29","TRTEDTM":"2023-10-29 14:35:29","TRT01SDTM":"2020-10-28 20:35:29","TRT01EDTM":"2022-10-29 08:35:29","TRT02SDTM":"2022-10-29 08:35:29","TRT02EDTM":"2023-10-29 14:35:29","AP01SDTM":"2020-10-28 20:35:29","AP01EDTM":"2022-10-29 08:35:29","AP02SDTM":"2022-10-29 08:35:29","AP02EDTM":"2023-10-29 14:35:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-29","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":86,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.18389,"AVALU":"mg/L","BASE2":9.51004,"BASE":11.18389,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.67384,"PCHG2":17.60081,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2021-05-13 20:35:29","ADY":197,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-221","SUBJID":"id-221","SITEID":"CHN-5","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.47576,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-24","TRTSDTM":"2020-10-28 20:35:29","TRTEDTM":"2023-10-29 14:35:29","TRT01SDTM":"2020-10-28 20:35:29","TRT01EDTM":"2022-10-29 08:35:29","TRT02SDTM":"2022-10-29 08:35:29","TRT02EDTM":"2023-10-29 14:35:29","AP01SDTM":"2020-10-28 20:35:29","AP01EDTM":"2022-10-29 08:35:29","AP02SDTM":"2022-10-29 08:35:29","AP02EDTM":"2023-10-29 14:35:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-29","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3178,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.16961,"AVALU":"mg/L","BASE2":9.51004,"BASE":11.18389,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.34043,"PCHG2":-14.09491,"CHG":-3.01428,"PCHG":-26.95196,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-11-15 20:35:29","ADY":383,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-221","SUBJID":"id-221","SITEID":"CHN-5","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.47576,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-24","TRTSDTM":"2020-10-28 20:35:29","TRTEDTM":"2023-10-29 14:35:29","TRT01SDTM":"2020-10-28 20:35:29","TRT01EDTM":"2022-10-29 08:35:29","TRT02SDTM":"2022-10-29 08:35:29","TRT02EDTM":"2023-10-29 14:35:29","AP01SDTM":"2020-10-28 20:35:29","AP01EDTM":"2022-10-29 08:35:29","AP02SDTM":"2022-10-29 08:35:29","AP02EDTM":"2023-10-29 14:35:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-29","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3498,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.26536,"AVALU":"mg/L","BASE2":9.51004,"BASE":11.18389,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.24468,"PCHG2":-13.0881,"CHG":-2.91853,"PCHG":-26.09583,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-05-04 20:35:29","ADY":553,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-221","SUBJID":"id-221","SITEID":"CHN-5","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.47576,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-24","TRTSDTM":"2020-10-28 20:35:29","TRTEDTM":"2023-10-29 14:35:29","TRT01SDTM":"2020-10-28 20:35:29","TRT01EDTM":"2022-10-29 08:35:29","TRT02SDTM":"2022-10-29 08:35:29","TRT02EDTM":"2023-10-29 14:35:29","AP01SDTM":"2020-10-28 20:35:29","AP01EDTM":"2022-10-29 08:35:29","AP02SDTM":"2022-10-29 08:35:29","AP02EDTM":"2023-10-29 14:35:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-29","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3895,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.42769,"AVALU":"mg/L","BASE2":9.51004,"BASE":11.18389,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.08235,"PCHG2":-11.38111,"CHG":-2.75619,"PCHG":-24.64432,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-05-13 20:35:29","ADY":562,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-221","SUBJID":"id-221","SITEID":"CHN-5","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.47576,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-24","TRTSDTM":"2020-10-28 20:35:29","TRTEDTM":"2023-10-29 14:35:29","TRT01SDTM":"2020-10-28 20:35:29","TRT01EDTM":"2022-10-29 08:35:29","TRT02SDTM":"2022-10-29 08:35:29","TRT02EDTM":"2023-10-29 14:35:29","AP01SDTM":"2020-10-28 20:35:29","AP01EDTM":"2022-10-29 08:35:29","AP02SDTM":"2022-10-29 08:35:29","AP02EDTM":"2023-10-29 14:35:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-29","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":356,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.80406,"AVALU":"mg/L","BASE2":9.51004,"BASE":11.18389,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.29402,"PCHG2":3.09168,"CHG":-1.37982,"PCHG":-12.3376,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-08-15 20:35:29","ADY":656,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-221","SUBJID":"id-221","SITEID":"CHN-5","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.47576,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-24","TRTSDTM":"2020-10-28 20:35:29","TRTEDTM":"2023-10-29 14:35:29","TRT01SDTM":"2020-10-28 20:35:29","TRT01EDTM":"2022-10-29 08:35:29","TRT02SDTM":"2022-10-29 08:35:29","TRT02EDTM":"2023-10-29 14:35:29","AP01SDTM":"2020-10-28 20:35:29","AP01EDTM":"2022-10-29 08:35:29","AP02SDTM":"2022-10-29 08:35:29","AP02EDTM":"2023-10-29 14:35:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-29","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2036,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.82068,"AVALU":"mg/L","BASE2":9.51004,"BASE":11.18389,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.31064,"PCHG2":3.2664,"CHG":-1.36321,"PCHG":-12.18903,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2023-04-12 20:35:29","ADY":896,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-221","SUBJID":"id-221","SITEID":"CHN-5","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.47576,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-24","TRTSDTM":"2020-10-28 20:35:29","TRTEDTM":"2023-10-29 14:35:29","TRT01SDTM":"2020-10-28 20:35:29","TRT01EDTM":"2022-10-29 08:35:29","TRT02SDTM":"2022-10-29 08:35:29","TRT02EDTM":"2023-10-29 14:35:29","AP01SDTM":"2020-10-28 20:35:29","AP01EDTM":"2022-10-29 08:35:29","AP02SDTM":"2022-10-29 08:35:29","AP02EDTM":"2023-10-29 14:35:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-29","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3846,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88048,"AVALU":"g/L","BASE2":2.88048,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-02-07 20:35:29","ADY":102,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-221","SUBJID":"id-221","SITEID":"CHN-5","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.47576,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-24","TRTSDTM":"2020-10-28 20:35:29","TRTEDTM":"2023-10-29 14:35:29","TRT01SDTM":"2020-10-28 20:35:29","TRT01EDTM":"2022-10-29 08:35:29","TRT02SDTM":"2022-10-29 08:35:29","TRT02EDTM":"2023-10-29 14:35:29","AP01SDTM":"2020-10-28 20:35:29","AP01EDTM":"2022-10-29 08:35:29","AP02SDTM":"2022-10-29 08:35:29","AP02EDTM":"2023-10-29 14:35:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-29","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7810,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02698,"AVALU":"g/L","BASE2":2.88048,"BASE":3.02698,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.1465,"PCHG2":5.08609,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2021-05-13 20:35:29","ADY":197,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-221","SUBJID":"id-221","SITEID":"CHN-5","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.47576,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-24","TRTSDTM":"2020-10-28 20:35:29","TRTEDTM":"2023-10-29 14:35:29","TRT01SDTM":"2020-10-28 20:35:29","TRT01EDTM":"2022-10-29 08:35:29","TRT02SDTM":"2022-10-29 08:35:29","TRT02EDTM":"2023-10-29 14:35:29","AP01SDTM":"2020-10-28 20:35:29","AP01EDTM":"2022-10-29 08:35:29","AP02SDTM":"2022-10-29 08:35:29","AP02EDTM":"2023-10-29 14:35:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-29","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":155,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.1512,"AVALU":"g/L","BASE2":2.88048,"BASE":3.02698,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.27072,"PCHG2":9.39859,"CHG":0.12422,"PCHG":4.10378,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"1","BTOXGR":"2","ADTM":"2021-11-15 20:35:29","ADY":383,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-221","SUBJID":"id-221","SITEID":"CHN-5","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.47576,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-24","TRTSDTM":"2020-10-28 20:35:29","TRTEDTM":"2023-10-29 14:35:29","TRT01SDTM":"2020-10-28 20:35:29","TRT01EDTM":"2022-10-29 08:35:29","TRT02SDTM":"2022-10-29 08:35:29","TRT02EDTM":"2023-10-29 14:35:29","AP01SDTM":"2020-10-28 20:35:29","AP01EDTM":"2022-10-29 08:35:29","AP02SDTM":"2022-10-29 08:35:29","AP02EDTM":"2023-10-29 14:35:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-29","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7011,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96705,"AVALU":"g/L","BASE2":2.88048,"BASE":3.02698,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08657,"PCHG2":3.00535,"CHG":-0.05994,"PCHG":-1.98003,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-05-04 20:35:29","ADY":553,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-221","SUBJID":"id-221","SITEID":"CHN-5","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.47576,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-24","TRTSDTM":"2020-10-28 20:35:29","TRTEDTM":"2023-10-29 14:35:29","TRT01SDTM":"2020-10-28 20:35:29","TRT01EDTM":"2022-10-29 08:35:29","TRT02SDTM":"2022-10-29 08:35:29","TRT02EDTM":"2023-10-29 14:35:29","AP01SDTM":"2020-10-28 20:35:29","AP01EDTM":"2022-10-29 08:35:29","AP02SDTM":"2022-10-29 08:35:29","AP02EDTM":"2023-10-29 14:35:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-29","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":797,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89366,"AVALU":"g/L","BASE2":2.88048,"BASE":3.02698,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01319,"PCHG2":0.45777,"CHG":-0.13332,"PCHG":-4.40431,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-05-13 20:35:29","ADY":562,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-221","SUBJID":"id-221","SITEID":"CHN-5","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.47576,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-24","TRTSDTM":"2020-10-28 20:35:29","TRTEDTM":"2023-10-29 14:35:29","TRT01SDTM":"2020-10-28 20:35:29","TRT01EDTM":"2022-10-29 08:35:29","TRT02SDTM":"2022-10-29 08:35:29","TRT02EDTM":"2023-10-29 14:35:29","AP01SDTM":"2020-10-28 20:35:29","AP01EDTM":"2022-10-29 08:35:29","AP02SDTM":"2022-10-29 08:35:29","AP02EDTM":"2023-10-29 14:35:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-29","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2987,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91494,"AVALU":"g/L","BASE2":2.88048,"BASE":3.02698,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03447,"PCHG2":1.19656,"CHG":-0.11204,"PCHG":-3.70128,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-08-15 20:35:29","ADY":656,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-221","SUBJID":"id-221","SITEID":"CHN-5","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.47576,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-24","TRTSDTM":"2020-10-28 20:35:29","TRTEDTM":"2023-10-29 14:35:29","TRT01SDTM":"2020-10-28 20:35:29","TRT01EDTM":"2022-10-29 08:35:29","TRT02SDTM":"2022-10-29 08:35:29","TRT02EDTM":"2023-10-29 14:35:29","AP01SDTM":"2020-10-28 20:35:29","AP01EDTM":"2022-10-29 08:35:29","AP02SDTM":"2022-10-29 08:35:29","AP02EDTM":"2023-10-29 14:35:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-29","EOSDY":1096,"LSTALVDT":"2023-11-16","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7037,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86548,"AVALU":"g/L","BASE2":2.88048,"BASE":3.02698,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01499,"PCHG2":-0.52054,"CHG":-0.1615,"PCHG":-5.33527,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2023-04-12 20:35:29","ADY":896,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-231","SUBJID":"id-231","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.59692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-03","TRTSDTM":"2020-12-07 16:13:10","TRTEDTM":"2022-02-18 20:24:38","TRT01SDTM":"2020-12-07 16:13:10","TRT01EDTM":"2021-02-18 14:24:38","TRT02SDTM":"2021-02-18 14:24:38","TRT02EDTM":"2022-02-18 20:24:38","AP01SDTM":"2020-12-07 16:13:10","AP01EDTM":"2021-02-18 14:24:38","AP02SDTM":"2021-02-18 14:24:38","AP02EDTM":"2022-02-18 20:24:38","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":439,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":468,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7618,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.64457,"AVALU":"U/L","BASE2":11.64457,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-22 16:13:10","ADY":46,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-231","SUBJID":"id-231","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.59692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-03","TRTSDTM":"2020-12-07 16:13:10","TRTEDTM":"2022-02-18 20:24:38","TRT01SDTM":"2020-12-07 16:13:10","TRT01EDTM":"2021-02-18 14:24:38","TRT02SDTM":"2021-02-18 14:24:38","TRT02EDTM":"2022-02-18 20:24:38","AP01SDTM":"2020-12-07 16:13:10","AP01EDTM":"2021-02-18 14:24:38","AP02SDTM":"2021-02-18 14:24:38","AP02EDTM":"2022-02-18 20:24:38","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":439,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":468,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2473,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.30446,"AVALU":"U/L","BASE2":11.64457,"BASE":16.30446,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":4.65989,"PCHG2":40.0177,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-17 16:13:10","ADY":192,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-231","SUBJID":"id-231","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.59692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-03","TRTSDTM":"2020-12-07 16:13:10","TRTEDTM":"2022-02-18 20:24:38","TRT01SDTM":"2020-12-07 16:13:10","TRT01EDTM":"2021-02-18 14:24:38","TRT02SDTM":"2021-02-18 14:24:38","TRT02EDTM":"2022-02-18 20:24:38","AP01SDTM":"2020-12-07 16:13:10","AP01EDTM":"2021-02-18 14:24:38","AP02SDTM":"2021-02-18 14:24:38","AP02EDTM":"2022-02-18 20:24:38","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":439,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":468,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2373,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.39968,"AVALU":"U/L","BASE2":11.64457,"BASE":16.30446,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.24489,"PCHG2":-79.39229,"CHG":-13.90478,"PCHG":-85.28207,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-07-30 16:13:10","ADY":235,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-231","SUBJID":"id-231","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.59692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-03","TRTSDTM":"2020-12-07 16:13:10","TRTEDTM":"2022-02-18 20:24:38","TRT01SDTM":"2020-12-07 16:13:10","TRT01EDTM":"2021-02-18 14:24:38","TRT02SDTM":"2021-02-18 14:24:38","TRT02EDTM":"2022-02-18 20:24:38","AP01SDTM":"2020-12-07 16:13:10","AP01EDTM":"2021-02-18 14:24:38","AP02SDTM":"2021-02-18 14:24:38","AP02EDTM":"2022-02-18 20:24:38","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":439,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":468,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4443,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.49435,"AVALU":"U/L","BASE2":11.64457,"BASE":16.30446,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.84978,"PCHG2":127.52539,"CHG":10.18989,"PCHG":62.49759,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-19 16:13:10","ADY":255,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-231","SUBJID":"id-231","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.59692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-03","TRTSDTM":"2020-12-07 16:13:10","TRTEDTM":"2022-02-18 20:24:38","TRT01SDTM":"2020-12-07 16:13:10","TRT01EDTM":"2021-02-18 14:24:38","TRT02SDTM":"2021-02-18 14:24:38","TRT02EDTM":"2022-02-18 20:24:38","AP01SDTM":"2020-12-07 16:13:10","AP01EDTM":"2021-02-18 14:24:38","AP02SDTM":"2021-02-18 14:24:38","AP02EDTM":"2022-02-18 20:24:38","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":439,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":468,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6220,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.1044,"AVALU":"U/L","BASE2":11.64457,"BASE":16.30446,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":22.45983,"PCHG2":192.87817,"CHG":17.79994,"PCHG":109.17225,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-25 16:13:10","ADY":292,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-231","SUBJID":"id-231","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.59692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-03","TRTSDTM":"2020-12-07 16:13:10","TRTEDTM":"2022-02-18 20:24:38","TRT01SDTM":"2020-12-07 16:13:10","TRT01EDTM":"2021-02-18 14:24:38","TRT02SDTM":"2021-02-18 14:24:38","TRT02EDTM":"2022-02-18 20:24:38","AP01SDTM":"2020-12-07 16:13:10","AP01EDTM":"2021-02-18 14:24:38","AP02SDTM":"2021-02-18 14:24:38","AP02EDTM":"2022-02-18 20:24:38","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":439,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":468,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8082,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.08098,"AVALU":"U/L","BASE2":11.64457,"BASE":16.30446,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.56359,"PCHG2":-13.42764,"CHG":-6.22348,"PCHG":-38.17042,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-11 16:13:10","ADY":308,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-231","SUBJID":"id-231","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.59692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-03","TRTSDTM":"2020-12-07 16:13:10","TRTEDTM":"2022-02-18 20:24:38","TRT01SDTM":"2020-12-07 16:13:10","TRT01EDTM":"2021-02-18 14:24:38","TRT02SDTM":"2021-02-18 14:24:38","TRT02EDTM":"2022-02-18 20:24:38","AP01SDTM":"2020-12-07 16:13:10","AP01EDTM":"2021-02-18 14:24:38","AP02SDTM":"2021-02-18 14:24:38","AP02EDTM":"2022-02-18 20:24:38","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":439,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":468,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8152,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.02012,"AVALU":"U/L","BASE2":11.64457,"BASE":16.30446,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.37555,"PCHG2":20.40046,"CHG":-2.28434,"PCHG":-14.01054,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-18 16:13:10","ADY":315,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-231","SUBJID":"id-231","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.59692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-03","TRTSDTM":"2020-12-07 16:13:10","TRTEDTM":"2022-02-18 20:24:38","TRT01SDTM":"2020-12-07 16:13:10","TRT01EDTM":"2021-02-18 14:24:38","TRT02SDTM":"2021-02-18 14:24:38","TRT02EDTM":"2022-02-18 20:24:38","AP01SDTM":"2020-12-07 16:13:10","AP01EDTM":"2021-02-18 14:24:38","AP02SDTM":"2021-02-18 14:24:38","AP02EDTM":"2022-02-18 20:24:38","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":439,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":468,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4433,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.57606,"AVALU":"mg/L","BASE2":7.57606,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"-3","BTOXGR":"1","ADTM":"2021-01-22 16:13:10","ADY":46,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-231","SUBJID":"id-231","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.59692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-03","TRTSDTM":"2020-12-07 16:13:10","TRTEDTM":"2022-02-18 20:24:38","TRT01SDTM":"2020-12-07 16:13:10","TRT01EDTM":"2021-02-18 14:24:38","TRT02SDTM":"2021-02-18 14:24:38","TRT02EDTM":"2022-02-18 20:24:38","AP01SDTM":"2020-12-07 16:13:10","AP01EDTM":"2021-02-18 14:24:38","AP02SDTM":"2021-02-18 14:24:38","AP02EDTM":"2022-02-18 20:24:38","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":439,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":468,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5111,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.50638,"AVALU":"mg/L","BASE2":7.57606,"BASE":10.50638,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.93032,"PCHG2":38.67863,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2021-06-17 16:13:10","ADY":192,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-231","SUBJID":"id-231","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.59692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-03","TRTSDTM":"2020-12-07 16:13:10","TRTEDTM":"2022-02-18 20:24:38","TRT01SDTM":"2020-12-07 16:13:10","TRT01EDTM":"2021-02-18 14:24:38","TRT02SDTM":"2021-02-18 14:24:38","TRT02EDTM":"2022-02-18 20:24:38","AP01SDTM":"2020-12-07 16:13:10","AP01EDTM":"2021-02-18 14:24:38","AP02SDTM":"2021-02-18 14:24:38","AP02EDTM":"2022-02-18 20:24:38","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":439,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":468,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7259,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.79399,"AVALU":"mg/L","BASE2":7.57606,"BASE":10.50638,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.21793,"PCHG2":16.07597,"CHG":-1.71239,"PCHG":-16.29859,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-07-30 16:13:10","ADY":235,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-231","SUBJID":"id-231","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.59692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-03","TRTSDTM":"2020-12-07 16:13:10","TRTEDTM":"2022-02-18 20:24:38","TRT01SDTM":"2020-12-07 16:13:10","TRT01EDTM":"2021-02-18 14:24:38","TRT02SDTM":"2021-02-18 14:24:38","TRT02EDTM":"2022-02-18 20:24:38","AP01SDTM":"2020-12-07 16:13:10","AP01EDTM":"2021-02-18 14:24:38","AP02SDTM":"2021-02-18 14:24:38","AP02EDTM":"2022-02-18 20:24:38","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":439,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":468,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":779,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.5075,"AVALU":"mg/L","BASE2":7.57606,"BASE":10.50638,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.93143,"PCHG2":38.69337,"CHG":0.00112,"PCHG":0.01063,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"4","BTOXGR":"1","ADTM":"2021-08-19 16:13:10","ADY":255,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-231","SUBJID":"id-231","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.59692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-03","TRTSDTM":"2020-12-07 16:13:10","TRTEDTM":"2022-02-18 20:24:38","TRT01SDTM":"2020-12-07 16:13:10","TRT01EDTM":"2021-02-18 14:24:38","TRT02SDTM":"2021-02-18 14:24:38","TRT02EDTM":"2022-02-18 20:24:38","AP01SDTM":"2020-12-07 16:13:10","AP01EDTM":"2021-02-18 14:24:38","AP02SDTM":"2021-02-18 14:24:38","AP02EDTM":"2022-02-18 20:24:38","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":439,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":468,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7614,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.25545,"AVALU":"mg/L","BASE2":7.57606,"BASE":10.50638,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.67939,"PCHG2":22.16701,"CHG":-1.25093,"PCHG":-11.9064,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-09-25 16:13:10","ADY":292,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-231","SUBJID":"id-231","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.59692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-03","TRTSDTM":"2020-12-07 16:13:10","TRTEDTM":"2022-02-18 20:24:38","TRT01SDTM":"2020-12-07 16:13:10","TRT01EDTM":"2021-02-18 14:24:38","TRT02SDTM":"2021-02-18 14:24:38","TRT02EDTM":"2022-02-18 20:24:38","AP01SDTM":"2020-12-07 16:13:10","AP01EDTM":"2021-02-18 14:24:38","AP02SDTM":"2021-02-18 14:24:38","AP02EDTM":"2022-02-18 20:24:38","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":439,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":468,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.08782,"AVALU":"mg/L","BASE2":7.57606,"BASE":10.50638,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.51175,"PCHG2":6.75488,"CHG":-2.41856,"PCHG":-23.01995,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-10-11 16:13:10","ADY":308,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-231","SUBJID":"id-231","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.59692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-03","TRTSDTM":"2020-12-07 16:13:10","TRTEDTM":"2022-02-18 20:24:38","TRT01SDTM":"2020-12-07 16:13:10","TRT01EDTM":"2021-02-18 14:24:38","TRT02SDTM":"2021-02-18 14:24:38","TRT02EDTM":"2022-02-18 20:24:38","AP01SDTM":"2020-12-07 16:13:10","AP01EDTM":"2021-02-18 14:24:38","AP02SDTM":"2021-02-18 14:24:38","AP02EDTM":"2022-02-18 20:24:38","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":439,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":468,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7270,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.34437,"AVALU":"mg/L","BASE2":7.57606,"BASE":10.50638,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.76831,"PCHG2":10.14127,"CHG":-2.16201,"PCHG":-20.57806,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-10-18 16:13:10","ADY":315,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-231","SUBJID":"id-231","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.59692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-03","TRTSDTM":"2020-12-07 16:13:10","TRTEDTM":"2022-02-18 20:24:38","TRT01SDTM":"2020-12-07 16:13:10","TRT01EDTM":"2021-02-18 14:24:38","TRT02SDTM":"2021-02-18 14:24:38","TRT02EDTM":"2022-02-18 20:24:38","AP01SDTM":"2020-12-07 16:13:10","AP01EDTM":"2021-02-18 14:24:38","AP02SDTM":"2021-02-18 14:24:38","AP02EDTM":"2022-02-18 20:24:38","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":439,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":468,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1510,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01531,"AVALU":"g/L","BASE2":3.01531,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-01-22 16:13:10","ADY":46,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-231","SUBJID":"id-231","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.59692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-03","TRTSDTM":"2020-12-07 16:13:10","TRTEDTM":"2022-02-18 20:24:38","TRT01SDTM":"2020-12-07 16:13:10","TRT01EDTM":"2021-02-18 14:24:38","TRT02SDTM":"2021-02-18 14:24:38","TRT02EDTM":"2022-02-18 20:24:38","AP01SDTM":"2020-12-07 16:13:10","AP01EDTM":"2021-02-18 14:24:38","AP02SDTM":"2021-02-18 14:24:38","AP02EDTM":"2022-02-18 20:24:38","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":439,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":468,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1745,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94766,"AVALU":"g/L","BASE2":3.01531,"BASE":2.94766,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.06764,"PCHG2":-2.2433,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-17 16:13:10","ADY":192,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-231","SUBJID":"id-231","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.59692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-03","TRTSDTM":"2020-12-07 16:13:10","TRTEDTM":"2022-02-18 20:24:38","TRT01SDTM":"2020-12-07 16:13:10","TRT01EDTM":"2021-02-18 14:24:38","TRT02SDTM":"2021-02-18 14:24:38","TRT02EDTM":"2022-02-18 20:24:38","AP01SDTM":"2020-12-07 16:13:10","AP01EDTM":"2021-02-18 14:24:38","AP02SDTM":"2021-02-18 14:24:38","AP02EDTM":"2022-02-18 20:24:38","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":439,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":468,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7998,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89591,"AVALU":"g/L","BASE2":3.01531,"BASE":2.94766,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1194,"PCHG2":-3.95973,"CHG":-0.05176,"PCHG":-1.75581,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-30 16:13:10","ADY":235,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-231","SUBJID":"id-231","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.59692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-03","TRTSDTM":"2020-12-07 16:13:10","TRTEDTM":"2022-02-18 20:24:38","TRT01SDTM":"2020-12-07 16:13:10","TRT01EDTM":"2021-02-18 14:24:38","TRT02SDTM":"2021-02-18 14:24:38","TRT02EDTM":"2022-02-18 20:24:38","AP01SDTM":"2020-12-07 16:13:10","AP01EDTM":"2021-02-18 14:24:38","AP02SDTM":"2021-02-18 14:24:38","AP02EDTM":"2022-02-18 20:24:38","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":439,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":468,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1219,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85231,"AVALU":"g/L","BASE2":3.01531,"BASE":2.94766,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.163,"PCHG2":-5.40569,"CHG":-0.09536,"PCHG":-3.23495,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-19 16:13:10","ADY":255,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-231","SUBJID":"id-231","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.59692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-03","TRTSDTM":"2020-12-07 16:13:10","TRTEDTM":"2022-02-18 20:24:38","TRT01SDTM":"2020-12-07 16:13:10","TRT01EDTM":"2021-02-18 14:24:38","TRT02SDTM":"2021-02-18 14:24:38","TRT02EDTM":"2022-02-18 20:24:38","AP01SDTM":"2020-12-07 16:13:10","AP01EDTM":"2021-02-18 14:24:38","AP02SDTM":"2021-02-18 14:24:38","AP02EDTM":"2022-02-18 20:24:38","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":439,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":468,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4754,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98219,"AVALU":"g/L","BASE2":3.01531,"BASE":2.94766,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03312,"PCHG2":-1.09831,"CHG":0.03453,"PCHG":1.17127,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-25 16:13:10","ADY":292,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-231","SUBJID":"id-231","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.59692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-03","TRTSDTM":"2020-12-07 16:13:10","TRTEDTM":"2022-02-18 20:24:38","TRT01SDTM":"2020-12-07 16:13:10","TRT01EDTM":"2021-02-18 14:24:38","TRT02SDTM":"2021-02-18 14:24:38","TRT02EDTM":"2022-02-18 20:24:38","AP01SDTM":"2020-12-07 16:13:10","AP01EDTM":"2021-02-18 14:24:38","AP02SDTM":"2021-02-18 14:24:38","AP02EDTM":"2022-02-18 20:24:38","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":439,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":468,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8120,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95944,"AVALU":"g/L","BASE2":3.01531,"BASE":2.94766,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05586,"PCHG2":-1.85259,"CHG":0.01178,"PCHG":0.39968,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-11 16:13:10","ADY":308,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-231","SUBJID":"id-231","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.59692,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-03","TRTSDTM":"2020-12-07 16:13:10","TRTEDTM":"2022-02-18 20:24:38","TRT01SDTM":"2020-12-07 16:13:10","TRT01EDTM":"2021-02-18 14:24:38","TRT02SDTM":"2021-02-18 14:24:38","TRT02EDTM":"2022-02-18 20:24:38","AP01SDTM":"2020-12-07 16:13:10","AP01EDTM":"2021-02-18 14:24:38","AP02SDTM":"2021-02-18 14:24:38","AP02EDTM":"2022-02-18 20:24:38","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":439,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":468,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":156,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0142,"AVALU":"g/L","BASE2":3.01531,"BASE":2.94766,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0011,"PCHG2":-0.03655,"CHG":0.06654,"PCHG":2.25739,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-10-18 16:13:10","ADY":315,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-273","SUBJID":"id-273","SITEID":"CHN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":10.53634,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-03 11:47:16","TRTEDTM":"2024-01-04 05:47:16","TRT01SDTM":"2021-01-03 11:47:16","TRT01EDTM":"2023-01-03 23:47:16","TRT02SDTM":"2023-01-03 23:47:16","TRT02EDTM":"2024-01-04 05:47:16","AP01SDTM":"2021-01-03 11:47:16","AP01EDTM":"2023-01-03 23:47:16","AP02SDTM":"2023-01-03 23:47:16","AP02EDTM":"2024-01-04 05:47:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-02-01","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7343,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.28855,"AVALU":"U/L","BASE2":19.28855,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-30 11:47:16","ADY":117,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-273","SUBJID":"id-273","SITEID":"CHN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":10.53634,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-03 11:47:16","TRTEDTM":"2024-01-04 05:47:16","TRT01SDTM":"2021-01-03 11:47:16","TRT01EDTM":"2023-01-03 23:47:16","TRT02SDTM":"2023-01-03 23:47:16","TRT02EDTM":"2024-01-04 05:47:16","AP01SDTM":"2021-01-03 11:47:16","AP01EDTM":"2023-01-03 23:47:16","AP02SDTM":"2023-01-03 23:47:16","AP02EDTM":"2024-01-04 05:47:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-02-01","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1830,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.43577,"AVALU":"U/L","BASE2":19.28855,"BASE":31.43577,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":12.14721,"PCHG2":62.97628,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-24 11:47:16","ADY":386,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-273","SUBJID":"id-273","SITEID":"CHN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":10.53634,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-03 11:47:16","TRTEDTM":"2024-01-04 05:47:16","TRT01SDTM":"2021-01-03 11:47:16","TRT01EDTM":"2023-01-03 23:47:16","TRT02SDTM":"2023-01-03 23:47:16","TRT02EDTM":"2024-01-04 05:47:16","AP01SDTM":"2021-01-03 11:47:16","AP01EDTM":"2023-01-03 23:47:16","AP02SDTM":"2023-01-03 23:47:16","AP02EDTM":"2024-01-04 05:47:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-02-01","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5669,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.34904,"AVALU":"U/L","BASE2":19.28855,"BASE":31.43577,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.06049,"PCHG2":5.49802,"CHG":-11.08673,"PCHG":-35.26787,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-09 11:47:16","ADY":461,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-273","SUBJID":"id-273","SITEID":"CHN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":10.53634,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-03 11:47:16","TRTEDTM":"2024-01-04 05:47:16","TRT01SDTM":"2021-01-03 11:47:16","TRT01EDTM":"2023-01-03 23:47:16","TRT02SDTM":"2023-01-03 23:47:16","TRT02EDTM":"2024-01-04 05:47:16","AP01SDTM":"2021-01-03 11:47:16","AP01EDTM":"2023-01-03 23:47:16","AP02SDTM":"2023-01-03 23:47:16","AP02EDTM":"2024-01-04 05:47:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-02-01","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1929,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.38563,"AVALU":"U/L","BASE2":19.28855,"BASE":31.43577,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.90293,"PCHG2":-51.34094,"CHG":-22.05014,"PCHG":-70.14347,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-14 11:47:16","ADY":588,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-273","SUBJID":"id-273","SITEID":"CHN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":10.53634,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-03 11:47:16","TRTEDTM":"2024-01-04 05:47:16","TRT01SDTM":"2021-01-03 11:47:16","TRT01EDTM":"2023-01-03 23:47:16","TRT02SDTM":"2023-01-03 23:47:16","TRT02EDTM":"2024-01-04 05:47:16","AP01SDTM":"2021-01-03 11:47:16","AP01EDTM":"2023-01-03 23:47:16","AP02SDTM":"2023-01-03 23:47:16","AP02EDTM":"2024-01-04 05:47:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-02-01","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":344,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.47986,"AVALU":"U/L","BASE2":19.28855,"BASE":31.43577,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.80869,"PCHG2":-35.29914,"CHG":-18.95591,"PCHG":-60.30044,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-06 11:47:16","ADY":672,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-273","SUBJID":"id-273","SITEID":"CHN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":10.53634,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-03 11:47:16","TRTEDTM":"2024-01-04 05:47:16","TRT01SDTM":"2021-01-03 11:47:16","TRT01EDTM":"2023-01-03 23:47:16","TRT02SDTM":"2023-01-03 23:47:16","TRT02EDTM":"2024-01-04 05:47:16","AP01SDTM":"2021-01-03 11:47:16","AP01EDTM":"2023-01-03 23:47:16","AP02SDTM":"2023-01-03 23:47:16","AP02EDTM":"2024-01-04 05:47:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-02-01","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2155,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.85677,"AVALU":"U/L","BASE2":19.28855,"BASE":31.43577,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.43178,"PCHG2":-74.82045,"CHG":-26.579,"PCHG":-84.55017,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2023-01-04 11:47:16","ADY":731,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-273","SUBJID":"id-273","SITEID":"CHN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":10.53634,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-03 11:47:16","TRTEDTM":"2024-01-04 05:47:16","TRT01SDTM":"2021-01-03 11:47:16","TRT01EDTM":"2023-01-03 23:47:16","TRT02SDTM":"2023-01-03 23:47:16","TRT02EDTM":"2024-01-04 05:47:16","AP01SDTM":"2021-01-03 11:47:16","AP01EDTM":"2023-01-03 23:47:16","AP02SDTM":"2023-01-03 23:47:16","AP02EDTM":"2024-01-04 05:47:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-02-01","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":269,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.81517,"AVALU":"U/L","BASE2":19.28855,"BASE":31.43577,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-15.47338,"PCHG2":-80.22055,"CHG":-27.6206,"PCHG":-87.8636,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2023-01-25 11:47:16","ADY":752,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-273","SUBJID":"id-273","SITEID":"CHN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":10.53634,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-03 11:47:16","TRTEDTM":"2024-01-04 05:47:16","TRT01SDTM":"2021-01-03 11:47:16","TRT01EDTM":"2023-01-03 23:47:16","TRT02SDTM":"2023-01-03 23:47:16","TRT02EDTM":"2024-01-04 05:47:16","AP01SDTM":"2021-01-03 11:47:16","AP01EDTM":"2023-01-03 23:47:16","AP02SDTM":"2023-01-03 23:47:16","AP02EDTM":"2024-01-04 05:47:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-02-01","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4363,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.97599,"AVALU":"mg/L","BASE2":8.97599,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-30 11:47:16","ADY":117,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-273","SUBJID":"id-273","SITEID":"CHN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":10.53634,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-03 11:47:16","TRTEDTM":"2024-01-04 05:47:16","TRT01SDTM":"2021-01-03 11:47:16","TRT01EDTM":"2023-01-03 23:47:16","TRT02SDTM":"2023-01-03 23:47:16","TRT02EDTM":"2024-01-04 05:47:16","AP01SDTM":"2021-01-03 11:47:16","AP01EDTM":"2023-01-03 23:47:16","AP02SDTM":"2023-01-03 23:47:16","AP02EDTM":"2024-01-04 05:47:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-02-01","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3486,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.62726,"AVALU":"mg/L","BASE2":8.97599,"BASE":8.62726,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.34873,"PCHG2":-3.88514,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-24 11:47:16","ADY":386,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-273","SUBJID":"id-273","SITEID":"CHN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":10.53634,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-03 11:47:16","TRTEDTM":"2024-01-04 05:47:16","TRT01SDTM":"2021-01-03 11:47:16","TRT01EDTM":"2023-01-03 23:47:16","TRT02SDTM":"2023-01-03 23:47:16","TRT02EDTM":"2024-01-04 05:47:16","AP01SDTM":"2021-01-03 11:47:16","AP01EDTM":"2023-01-03 23:47:16","AP02SDTM":"2023-01-03 23:47:16","AP02EDTM":"2024-01-04 05:47:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-02-01","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8208,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.45178,"AVALU":"mg/L","BASE2":8.97599,"BASE":8.62726,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.47579,"PCHG2":16.44154,"CHG":1.82452,"PCHG":21.14832,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-04-09 11:47:16","ADY":461,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-273","SUBJID":"id-273","SITEID":"CHN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":10.53634,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-03 11:47:16","TRTEDTM":"2024-01-04 05:47:16","TRT01SDTM":"2021-01-03 11:47:16","TRT01EDTM":"2023-01-03 23:47:16","TRT02SDTM":"2023-01-03 23:47:16","TRT02EDTM":"2024-01-04 05:47:16","AP01SDTM":"2021-01-03 11:47:16","AP01EDTM":"2023-01-03 23:47:16","AP02SDTM":"2023-01-03 23:47:16","AP02EDTM":"2024-01-04 05:47:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-02-01","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2700,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.74168,"AVALU":"mg/L","BASE2":8.97599,"BASE":8.62726,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.23431,"PCHG2":-2.61039,"CHG":0.11442,"PCHG":1.32628,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-14 11:47:16","ADY":588,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-273","SUBJID":"id-273","SITEID":"CHN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":10.53634,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-03 11:47:16","TRTEDTM":"2024-01-04 05:47:16","TRT01SDTM":"2021-01-03 11:47:16","TRT01EDTM":"2023-01-03 23:47:16","TRT02SDTM":"2023-01-03 23:47:16","TRT02EDTM":"2024-01-04 05:47:16","AP01SDTM":"2021-01-03 11:47:16","AP01EDTM":"2023-01-03 23:47:16","AP02SDTM":"2023-01-03 23:47:16","AP02EDTM":"2024-01-04 05:47:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-02-01","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7713,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.81311,"AVALU":"mg/L","BASE2":8.97599,"BASE":8.62726,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16288,"PCHG2":-1.81457,"CHG":0.18585,"PCHG":2.15427,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-06 11:47:16","ADY":672,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-273","SUBJID":"id-273","SITEID":"CHN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":10.53634,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-03 11:47:16","TRTEDTM":"2024-01-04 05:47:16","TRT01SDTM":"2021-01-03 11:47:16","TRT01EDTM":"2023-01-03 23:47:16","TRT02SDTM":"2023-01-03 23:47:16","TRT02EDTM":"2024-01-04 05:47:16","AP01SDTM":"2021-01-03 11:47:16","AP01EDTM":"2023-01-03 23:47:16","AP02SDTM":"2023-01-03 23:47:16","AP02EDTM":"2024-01-04 05:47:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-02-01","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2480,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.47496,"AVALU":"mg/L","BASE2":8.97599,"BASE":8.62726,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.50103,"PCHG2":-27.86352,"CHG":-2.1523,"PCHG":-24.94763,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2023-01-04 11:47:16","ADY":731,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-273","SUBJID":"id-273","SITEID":"CHN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":10.53634,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-03 11:47:16","TRTEDTM":"2024-01-04 05:47:16","TRT01SDTM":"2021-01-03 11:47:16","TRT01EDTM":"2023-01-03 23:47:16","TRT02SDTM":"2023-01-03 23:47:16","TRT02EDTM":"2024-01-04 05:47:16","AP01SDTM":"2021-01-03 11:47:16","AP01EDTM":"2023-01-03 23:47:16","AP02SDTM":"2023-01-03 23:47:16","AP02EDTM":"2024-01-04 05:47:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-02-01","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7576,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.13473,"AVALU":"mg/L","BASE2":8.97599,"BASE":8.62726,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.84126,"PCHG2":-9.37229,"CHG":-0.49253,"PCHG":-5.70895,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-25 11:47:16","ADY":752,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-273","SUBJID":"id-273","SITEID":"CHN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":10.53634,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-03 11:47:16","TRTEDTM":"2024-01-04 05:47:16","TRT01SDTM":"2021-01-03 11:47:16","TRT01EDTM":"2023-01-03 23:47:16","TRT02SDTM":"2023-01-03 23:47:16","TRT02EDTM":"2024-01-04 05:47:16","AP01SDTM":"2021-01-03 11:47:16","AP01EDTM":"2023-01-03 23:47:16","AP02SDTM":"2023-01-03 23:47:16","AP02EDTM":"2024-01-04 05:47:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-02-01","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":597,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7089,"AVALU":"g/L","BASE2":2.7089,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-30 11:47:16","ADY":117,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-273","SUBJID":"id-273","SITEID":"CHN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":10.53634,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-03 11:47:16","TRTEDTM":"2024-01-04 05:47:16","TRT01SDTM":"2021-01-03 11:47:16","TRT01EDTM":"2023-01-03 23:47:16","TRT02SDTM":"2023-01-03 23:47:16","TRT02EDTM":"2024-01-04 05:47:16","AP01SDTM":"2021-01-03 11:47:16","AP01EDTM":"2023-01-03 23:47:16","AP02SDTM":"2023-01-03 23:47:16","AP02EDTM":"2024-01-04 05:47:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-02-01","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2805,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92294,"AVALU":"g/L","BASE2":2.7089,"BASE":2.92294,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.21404,"PCHG2":7.90151,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-24 11:47:16","ADY":386,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-273","SUBJID":"id-273","SITEID":"CHN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":10.53634,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-03 11:47:16","TRTEDTM":"2024-01-04 05:47:16","TRT01SDTM":"2021-01-03 11:47:16","TRT01EDTM":"2023-01-03 23:47:16","TRT02SDTM":"2023-01-03 23:47:16","TRT02EDTM":"2024-01-04 05:47:16","AP01SDTM":"2021-01-03 11:47:16","AP01EDTM":"2023-01-03 23:47:16","AP02SDTM":"2023-01-03 23:47:16","AP02EDTM":"2024-01-04 05:47:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-02-01","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5472,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79261,"AVALU":"g/L","BASE2":2.7089,"BASE":2.92294,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08371,"PCHG2":3.09014,"CHG":-0.13034,"PCHG":-4.45904,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-09 11:47:16","ADY":461,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-273","SUBJID":"id-273","SITEID":"CHN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":10.53634,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-03 11:47:16","TRTEDTM":"2024-01-04 05:47:16","TRT01SDTM":"2021-01-03 11:47:16","TRT01EDTM":"2023-01-03 23:47:16","TRT02SDTM":"2023-01-03 23:47:16","TRT02EDTM":"2024-01-04 05:47:16","AP01SDTM":"2021-01-03 11:47:16","AP01EDTM":"2023-01-03 23:47:16","AP02SDTM":"2023-01-03 23:47:16","AP02EDTM":"2024-01-04 05:47:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-02-01","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7167,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05965,"AVALU":"g/L","BASE2":2.7089,"BASE":2.92294,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.35075,"PCHG2":12.94811,"CHG":0.13671,"PCHG":4.67704,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-08-14 11:47:16","ADY":588,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-273","SUBJID":"id-273","SITEID":"CHN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":10.53634,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-03 11:47:16","TRTEDTM":"2024-01-04 05:47:16","TRT01SDTM":"2021-01-03 11:47:16","TRT01EDTM":"2023-01-03 23:47:16","TRT02SDTM":"2023-01-03 23:47:16","TRT02EDTM":"2024-01-04 05:47:16","AP01SDTM":"2021-01-03 11:47:16","AP01EDTM":"2023-01-03 23:47:16","AP02SDTM":"2023-01-03 23:47:16","AP02EDTM":"2024-01-04 05:47:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-02-01","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4928,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93776,"AVALU":"g/L","BASE2":2.7089,"BASE":2.92294,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.22886,"PCHG2":8.44846,"CHG":0.01482,"PCHG":0.50689,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-06 11:47:16","ADY":672,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-273","SUBJID":"id-273","SITEID":"CHN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":10.53634,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-03 11:47:16","TRTEDTM":"2024-01-04 05:47:16","TRT01SDTM":"2021-01-03 11:47:16","TRT01EDTM":"2023-01-03 23:47:16","TRT02SDTM":"2023-01-03 23:47:16","TRT02EDTM":"2024-01-04 05:47:16","AP01SDTM":"2021-01-03 11:47:16","AP01EDTM":"2023-01-03 23:47:16","AP02SDTM":"2023-01-03 23:47:16","AP02EDTM":"2024-01-04 05:47:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-02-01","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6859,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74284,"AVALU":"g/L","BASE2":2.7089,"BASE":2.92294,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03394,"PCHG2":1.25294,"CHG":-0.1801,"PCHG":-6.1617,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-04 11:47:16","ADY":731,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-273","SUBJID":"id-273","SITEID":"CHN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":10.53634,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-03 11:47:16","TRTEDTM":"2024-01-04 05:47:16","TRT01SDTM":"2021-01-03 11:47:16","TRT01EDTM":"2023-01-03 23:47:16","TRT02SDTM":"2023-01-03 23:47:16","TRT02EDTM":"2024-01-04 05:47:16","AP01SDTM":"2021-01-03 11:47:16","AP01EDTM":"2023-01-03 23:47:16","AP02SDTM":"2023-01-03 23:47:16","AP02EDTM":"2024-01-04 05:47:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-04","EOSDY":1096,"LSTALVDT":"2024-02-01","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":745,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76016,"AVALU":"g/L","BASE2":2.7089,"BASE":2.92294,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05126,"PCHG2":1.89227,"CHG":-0.16278,"PCHG":-5.56919,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-25 11:47:16","ADY":752,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-338","SUBJID":"id-338","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.37538,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-08","TRTSDTM":"2019-08-09 23:27:53","TRTEDTM":"2022-02-20 03:47:56","TRT01SDTM":"2019-08-09 23:27:53","TRT01EDTM":"2021-02-19 21:47:56","TRT02SDTM":"2021-02-19 21:47:56","TRT02EDTM":"2022-02-20 03:47:56","AP01SDTM":"2019-08-09 23:27:53","AP01EDTM":"2021-02-19 21:47:56","AP02SDTM":"2021-02-19 21:47:56","AP02EDTM":"2022-02-20 03:47:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":926,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-13","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4993,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.31331,"AVALU":"U/L","BASE2":12.31331,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-05-20 23:27:53","ADY":285,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-338","SUBJID":"id-338","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.37538,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-08","TRTSDTM":"2019-08-09 23:27:53","TRTEDTM":"2022-02-20 03:47:56","TRT01SDTM":"2019-08-09 23:27:53","TRT01EDTM":"2021-02-19 21:47:56","TRT02SDTM":"2021-02-19 21:47:56","TRT02EDTM":"2022-02-20 03:47:56","AP01SDTM":"2019-08-09 23:27:53","AP01EDTM":"2021-02-19 21:47:56","AP02SDTM":"2021-02-19 21:47:56","AP02EDTM":"2022-02-20 03:47:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":926,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-13","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5276,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.23766,"AVALU":"U/L","BASE2":12.31331,"BASE":2.23766,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-10.07565,"PCHG2":-81.82728,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2020-06-26 23:27:53","ADY":322,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-338","SUBJID":"id-338","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.37538,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-08","TRTSDTM":"2019-08-09 23:27:53","TRTEDTM":"2022-02-20 03:47:56","TRT01SDTM":"2019-08-09 23:27:53","TRT01EDTM":"2021-02-19 21:47:56","TRT02SDTM":"2021-02-19 21:47:56","TRT02EDTM":"2022-02-20 03:47:56","AP01SDTM":"2019-08-09 23:27:53","AP01EDTM":"2021-02-19 21:47:56","AP02SDTM":"2021-02-19 21:47:56","AP02EDTM":"2022-02-20 03:47:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":926,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-13","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1301,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.754,"AVALU":"U/L","BASE2":12.31331,"BASE":2.23766,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.44068,"PCHG2":157.88345,"CHG":29.51633,"PCHG":1319.06872,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-07-26 23:27:53","ADY":352,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-338","SUBJID":"id-338","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.37538,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-08","TRTSDTM":"2019-08-09 23:27:53","TRTEDTM":"2022-02-20 03:47:56","TRT01SDTM":"2019-08-09 23:27:53","TRT01EDTM":"2021-02-19 21:47:56","TRT02SDTM":"2021-02-19 21:47:56","TRT02EDTM":"2022-02-20 03:47:56","AP01SDTM":"2019-08-09 23:27:53","AP01EDTM":"2021-02-19 21:47:56","AP02SDTM":"2021-02-19 21:47:56","AP02EDTM":"2022-02-20 03:47:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":926,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-13","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":339,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.36682,"AVALU":"U/L","BASE2":12.31331,"BASE":2.23766,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.0535,"PCHG2":81.64744,"CHG":20.12915,"PCHG":899.56084,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-08-08 23:27:53","ADY":365,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-338","SUBJID":"id-338","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.37538,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-08","TRTSDTM":"2019-08-09 23:27:53","TRTEDTM":"2022-02-20 03:47:56","TRT01SDTM":"2019-08-09 23:27:53","TRT01EDTM":"2021-02-19 21:47:56","TRT02SDTM":"2021-02-19 21:47:56","TRT02EDTM":"2022-02-20 03:47:56","AP01SDTM":"2019-08-09 23:27:53","AP01EDTM":"2021-02-19 21:47:56","AP02SDTM":"2021-02-19 21:47:56","AP02EDTM":"2022-02-20 03:47:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":926,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-13","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2284,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.49756,"AVALU":"U/L","BASE2":12.31331,"BASE":2.23766,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.81575,"PCHG2":-95.95916,"CHG":-1.7401,"PCHG":-77.76425,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-4","BTOXGR":"-1","ADTM":"2020-09-25 23:27:53","ADY":413,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-338","SUBJID":"id-338","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.37538,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-08","TRTSDTM":"2019-08-09 23:27:53","TRTEDTM":"2022-02-20 03:47:56","TRT01SDTM":"2019-08-09 23:27:53","TRT01EDTM":"2021-02-19 21:47:56","TRT02SDTM":"2021-02-19 21:47:56","TRT02EDTM":"2022-02-20 03:47:56","AP01SDTM":"2019-08-09 23:27:53","AP01EDTM":"2021-02-19 21:47:56","AP02SDTM":"2021-02-19 21:47:56","AP02EDTM":"2022-02-20 03:47:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":926,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-13","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3700,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.81534,"AVALU":"U/L","BASE2":12.31331,"BASE":2.23766,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.50203,"PCHG2":69.04746,"CHG":18.57768,"PCHG":830.22629,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-07-21 23:27:53","ADY":712,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-338","SUBJID":"id-338","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.37538,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-08","TRTSDTM":"2019-08-09 23:27:53","TRTEDTM":"2022-02-20 03:47:56","TRT01SDTM":"2019-08-09 23:27:53","TRT01EDTM":"2021-02-19 21:47:56","TRT02SDTM":"2021-02-19 21:47:56","TRT02EDTM":"2022-02-20 03:47:56","AP01SDTM":"2019-08-09 23:27:53","AP01EDTM":"2021-02-19 21:47:56","AP02SDTM":"2021-02-19 21:47:56","AP02EDTM":"2022-02-20 03:47:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":926,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-13","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":988,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.02963,"AVALU":"U/L","BASE2":12.31331,"BASE":2.23766,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.28368,"PCHG2":-2.30383,"CHG":9.79197,"PCHG":437.5978,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-01-21 23:27:53","ADY":896,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-338","SUBJID":"id-338","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.37538,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-08","TRTSDTM":"2019-08-09 23:27:53","TRTEDTM":"2022-02-20 03:47:56","TRT01SDTM":"2019-08-09 23:27:53","TRT01EDTM":"2021-02-19 21:47:56","TRT02SDTM":"2021-02-19 21:47:56","TRT02EDTM":"2022-02-20 03:47:56","AP01SDTM":"2019-08-09 23:27:53","AP01EDTM":"2021-02-19 21:47:56","AP02SDTM":"2021-02-19 21:47:56","AP02EDTM":"2022-02-20 03:47:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":926,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-13","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5489,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.51349,"AVALU":"mg/L","BASE2":8.51349,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-05-20 23:27:53","ADY":285,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-338","SUBJID":"id-338","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.37538,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-08","TRTSDTM":"2019-08-09 23:27:53","TRTEDTM":"2022-02-20 03:47:56","TRT01SDTM":"2019-08-09 23:27:53","TRT01EDTM":"2021-02-19 21:47:56","TRT02SDTM":"2021-02-19 21:47:56","TRT02EDTM":"2022-02-20 03:47:56","AP01SDTM":"2019-08-09 23:27:53","AP01EDTM":"2021-02-19 21:47:56","AP02SDTM":"2021-02-19 21:47:56","AP02EDTM":"2022-02-20 03:47:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":926,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-13","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1687,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.04109,"AVALU":"mg/L","BASE2":8.51349,"BASE":10.04109,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.52759,"PCHG2":17.9432,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-06-26 23:27:53","ADY":322,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-338","SUBJID":"id-338","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.37538,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-08","TRTSDTM":"2019-08-09 23:27:53","TRTEDTM":"2022-02-20 03:47:56","TRT01SDTM":"2019-08-09 23:27:53","TRT01EDTM":"2021-02-19 21:47:56","TRT02SDTM":"2021-02-19 21:47:56","TRT02EDTM":"2022-02-20 03:47:56","AP01SDTM":"2019-08-09 23:27:53","AP01EDTM":"2021-02-19 21:47:56","AP02SDTM":"2021-02-19 21:47:56","AP02EDTM":"2022-02-20 03:47:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":926,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-13","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3583,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.39476,"AVALU":"mg/L","BASE2":8.51349,"BASE":10.04109,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.11873,"PCHG2":-13.14071,"CHG":-2.64633,"PCHG":-26.35498,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-4","BTOXGR":"1","ADTM":"2020-07-26 23:27:53","ADY":352,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-338","SUBJID":"id-338","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.37538,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-08","TRTSDTM":"2019-08-09 23:27:53","TRTEDTM":"2022-02-20 03:47:56","TRT01SDTM":"2019-08-09 23:27:53","TRT01EDTM":"2021-02-19 21:47:56","TRT02SDTM":"2021-02-19 21:47:56","TRT02EDTM":"2022-02-20 03:47:56","AP01SDTM":"2019-08-09 23:27:53","AP01EDTM":"2021-02-19 21:47:56","AP02SDTM":"2021-02-19 21:47:56","AP02EDTM":"2022-02-20 03:47:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":926,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-13","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6978,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.17345,"AVALU":"mg/L","BASE2":8.51349,"BASE":10.04109,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.34004,"PCHG2":-3.99417,"CHG":-1.86764,"PCHG":-18.59994,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-08-08 23:27:53","ADY":365,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-338","SUBJID":"id-338","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.37538,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-08","TRTSDTM":"2019-08-09 23:27:53","TRTEDTM":"2022-02-20 03:47:56","TRT01SDTM":"2019-08-09 23:27:53","TRT01EDTM":"2021-02-19 21:47:56","TRT02SDTM":"2021-02-19 21:47:56","TRT02EDTM":"2022-02-20 03:47:56","AP01SDTM":"2019-08-09 23:27:53","AP01EDTM":"2021-02-19 21:47:56","AP02SDTM":"2021-02-19 21:47:56","AP02EDTM":"2022-02-20 03:47:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":926,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-13","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5616,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.84013,"AVALU":"mg/L","BASE2":8.51349,"BASE":10.04109,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.67336,"PCHG2":-7.90933,"CHG":-2.20095,"PCHG":-21.91947,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-2","BTOXGR":"1","ADTM":"2020-09-25 23:27:53","ADY":413,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-338","SUBJID":"id-338","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.37538,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-08","TRTSDTM":"2019-08-09 23:27:53","TRTEDTM":"2022-02-20 03:47:56","TRT01SDTM":"2019-08-09 23:27:53","TRT01EDTM":"2021-02-19 21:47:56","TRT02SDTM":"2021-02-19 21:47:56","TRT02EDTM":"2022-02-20 03:47:56","AP01SDTM":"2019-08-09 23:27:53","AP01EDTM":"2021-02-19 21:47:56","AP02SDTM":"2021-02-19 21:47:56","AP02EDTM":"2022-02-20 03:47:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":926,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-13","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2504,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.98228,"AVALU":"mg/L","BASE2":8.51349,"BASE":10.04109,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.46879,"PCHG2":5.50641,"CHG":-1.05881,"PCHG":-10.54473,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-07-21 23:27:53","ADY":712,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-338","SUBJID":"id-338","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.37538,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-08","TRTSDTM":"2019-08-09 23:27:53","TRTEDTM":"2022-02-20 03:47:56","TRT01SDTM":"2019-08-09 23:27:53","TRT01EDTM":"2021-02-19 21:47:56","TRT02SDTM":"2021-02-19 21:47:56","TRT02EDTM":"2022-02-20 03:47:56","AP01SDTM":"2019-08-09 23:27:53","AP01EDTM":"2021-02-19 21:47:56","AP02SDTM":"2021-02-19 21:47:56","AP02EDTM":"2022-02-20 03:47:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":926,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-13","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4570,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.50712,"AVALU":"mg/L","BASE2":8.51349,"BASE":10.04109,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.00637,"PCHG2":-11.82089,"CHG":-2.53396,"PCHG":-25.23596,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-2","BTOXGR":"1","ADTM":"2022-01-21 23:27:53","ADY":896,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-338","SUBJID":"id-338","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.37538,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-08","TRTSDTM":"2019-08-09 23:27:53","TRTEDTM":"2022-02-20 03:47:56","TRT01SDTM":"2019-08-09 23:27:53","TRT01EDTM":"2021-02-19 21:47:56","TRT02SDTM":"2021-02-19 21:47:56","TRT02EDTM":"2022-02-20 03:47:56","AP01SDTM":"2019-08-09 23:27:53","AP01EDTM":"2021-02-19 21:47:56","AP02SDTM":"2021-02-19 21:47:56","AP02EDTM":"2022-02-20 03:47:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":926,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-13","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4314,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91,"AVALU":"g/L","BASE2":2.91,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-20 23:27:53","ADY":285,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-338","SUBJID":"id-338","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.37538,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-08","TRTSDTM":"2019-08-09 23:27:53","TRTEDTM":"2022-02-20 03:47:56","TRT01SDTM":"2019-08-09 23:27:53","TRT01EDTM":"2021-02-19 21:47:56","TRT02SDTM":"2021-02-19 21:47:56","TRT02EDTM":"2022-02-20 03:47:56","AP01SDTM":"2019-08-09 23:27:53","AP01EDTM":"2021-02-19 21:47:56","AP02SDTM":"2021-02-19 21:47:56","AP02EDTM":"2022-02-20 03:47:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":926,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-13","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3862,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78255,"AVALU":"g/L","BASE2":2.91,"BASE":2.78255,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.12745,"PCHG2":-4.37976,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-26 23:27:53","ADY":322,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-338","SUBJID":"id-338","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.37538,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-08","TRTSDTM":"2019-08-09 23:27:53","TRTEDTM":"2022-02-20 03:47:56","TRT01SDTM":"2019-08-09 23:27:53","TRT01EDTM":"2021-02-19 21:47:56","TRT02SDTM":"2021-02-19 21:47:56","TRT02EDTM":"2022-02-20 03:47:56","AP01SDTM":"2019-08-09 23:27:53","AP01EDTM":"2021-02-19 21:47:56","AP02SDTM":"2021-02-19 21:47:56","AP02EDTM":"2022-02-20 03:47:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":926,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-13","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7898,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05261,"AVALU":"g/L","BASE2":2.91,"BASE":2.78255,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14262,"PCHG2":4.9009,"CHG":0.27007,"PCHG":9.70575,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-07-26 23:27:53","ADY":352,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-338","SUBJID":"id-338","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.37538,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-08","TRTSDTM":"2019-08-09 23:27:53","TRTEDTM":"2022-02-20 03:47:56","TRT01SDTM":"2019-08-09 23:27:53","TRT01EDTM":"2021-02-19 21:47:56","TRT02SDTM":"2021-02-19 21:47:56","TRT02EDTM":"2022-02-20 03:47:56","AP01SDTM":"2019-08-09 23:27:53","AP01EDTM":"2021-02-19 21:47:56","AP02SDTM":"2021-02-19 21:47:56","AP02EDTM":"2022-02-20 03:47:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":926,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-13","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3534,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91905,"AVALU":"g/L","BASE2":2.91,"BASE":2.78255,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00905,"PCHG2":0.31102,"CHG":0.1365,"PCHG":4.90563,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-08 23:27:53","ADY":365,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-338","SUBJID":"id-338","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.37538,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-08","TRTSDTM":"2019-08-09 23:27:53","TRTEDTM":"2022-02-20 03:47:56","TRT01SDTM":"2019-08-09 23:27:53","TRT01EDTM":"2021-02-19 21:47:56","TRT02SDTM":"2021-02-19 21:47:56","TRT02EDTM":"2022-02-20 03:47:56","AP01SDTM":"2019-08-09 23:27:53","AP01EDTM":"2021-02-19 21:47:56","AP02SDTM":"2021-02-19 21:47:56","AP02EDTM":"2022-02-20 03:47:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":926,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-13","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5136,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80243,"AVALU":"g/L","BASE2":2.91,"BASE":2.78255,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10756,"PCHG2":-3.69632,"CHG":0.01989,"PCHG":0.71474,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-25 23:27:53","ADY":413,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-338","SUBJID":"id-338","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.37538,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-08","TRTSDTM":"2019-08-09 23:27:53","TRTEDTM":"2022-02-20 03:47:56","TRT01SDTM":"2019-08-09 23:27:53","TRT01EDTM":"2021-02-19 21:47:56","TRT02SDTM":"2021-02-19 21:47:56","TRT02EDTM":"2022-02-20 03:47:56","AP01SDTM":"2019-08-09 23:27:53","AP01EDTM":"2021-02-19 21:47:56","AP02SDTM":"2021-02-19 21:47:56","AP02EDTM":"2022-02-20 03:47:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":926,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-13","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6062,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.08124,"AVALU":"g/L","BASE2":2.91,"BASE":2.78255,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17124,"PCHG2":5.8845,"CHG":0.29869,"PCHG":10.7344,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-07-21 23:27:53","ADY":712,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-338","SUBJID":"id-338","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.37538,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-08","TRTSDTM":"2019-08-09 23:27:53","TRTEDTM":"2022-02-20 03:47:56","TRT01SDTM":"2019-08-09 23:27:53","TRT01EDTM":"2021-02-19 21:47:56","TRT02SDTM":"2021-02-19 21:47:56","TRT02EDTM":"2022-02-20 03:47:56","AP01SDTM":"2019-08-09 23:27:53","AP01EDTM":"2021-02-19 21:47:56","AP02SDTM":"2021-02-19 21:47:56","AP02EDTM":"2022-02-20 03:47:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":926,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-13","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":383,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80437,"AVALU":"g/L","BASE2":2.91,"BASE":2.78255,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10562,"PCHG2":-3.62963,"CHG":0.02183,"PCHG":0.78449,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-21 23:27:53","ADY":896,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-348","SUBJID":"id-348","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.3549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-21","TRTSDTM":"2020-09-23 08:41:18","TRTEDTM":"2023-09-24 02:41:18","TRT01SDTM":"2020-09-23 08:41:18","TRT01EDTM":"2022-09-23 20:41:18","TRT02SDTM":"2022-09-23 20:41:18","TRT02EDTM":"2023-09-24 02:41:18","AP01SDTM":"2020-09-23 08:41:18","AP01EDTM":"2022-09-23 20:41:18","AP02SDTM":"2022-09-23 20:41:18","AP02EDTM":"2023-09-24 02:41:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-24","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4094,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.94313,"AVALU":"U/L","BASE2":22.94313,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-20 08:41:18","ADY":392,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-348","SUBJID":"id-348","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.3549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-21","TRTSDTM":"2020-09-23 08:41:18","TRTEDTM":"2023-09-24 02:41:18","TRT01SDTM":"2020-09-23 08:41:18","TRT01EDTM":"2022-09-23 20:41:18","TRT02SDTM":"2022-09-23 20:41:18","TRT02EDTM":"2023-09-24 02:41:18","AP01SDTM":"2020-09-23 08:41:18","AP01EDTM":"2022-09-23 20:41:18","AP02SDTM":"2022-09-23 20:41:18","AP02EDTM":"2023-09-24 02:41:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-24","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2058,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":36.54245,"AVALU":"U/L","BASE2":22.94313,"BASE":36.54245,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":13.59932,"PCHG2":59.27403,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-21 08:41:18","ADY":485,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-348","SUBJID":"id-348","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.3549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-21","TRTSDTM":"2020-09-23 08:41:18","TRTEDTM":"2023-09-24 02:41:18","TRT01SDTM":"2020-09-23 08:41:18","TRT01EDTM":"2022-09-23 20:41:18","TRT02SDTM":"2022-09-23 20:41:18","TRT02EDTM":"2023-09-24 02:41:18","AP01SDTM":"2020-09-23 08:41:18","AP01EDTM":"2022-09-23 20:41:18","AP02SDTM":"2022-09-23 20:41:18","AP02EDTM":"2023-09-24 02:41:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-24","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5468,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.60736,"AVALU":"U/L","BASE2":22.94313,"BASE":36.54245,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.66423,"PCHG2":20.32952,"CHG":-8.93509,"PCHG":-24.45126,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-17 08:41:18","ADY":571,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-348","SUBJID":"id-348","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.3549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-21","TRTSDTM":"2020-09-23 08:41:18","TRTEDTM":"2023-09-24 02:41:18","TRT01SDTM":"2020-09-23 08:41:18","TRT01EDTM":"2022-09-23 20:41:18","TRT02SDTM":"2022-09-23 20:41:18","TRT02EDTM":"2023-09-24 02:41:18","AP01SDTM":"2020-09-23 08:41:18","AP01EDTM":"2022-09-23 20:41:18","AP02SDTM":"2022-09-23 20:41:18","AP02EDTM":"2023-09-24 02:41:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-24","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8041,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.65557,"AVALU":"U/L","BASE2":22.94313,"BASE":36.54245,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-19.28756,"PCHG2":-84.06681,"CHG":-32.88687,"PCHG":-89.99636,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-06-09 08:41:18","ADY":624,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-348","SUBJID":"id-348","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.3549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-21","TRTSDTM":"2020-09-23 08:41:18","TRTEDTM":"2023-09-24 02:41:18","TRT01SDTM":"2020-09-23 08:41:18","TRT01EDTM":"2022-09-23 20:41:18","TRT02SDTM":"2022-09-23 20:41:18","TRT02EDTM":"2023-09-24 02:41:18","AP01SDTM":"2020-09-23 08:41:18","AP01EDTM":"2022-09-23 20:41:18","AP02SDTM":"2022-09-23 20:41:18","AP02EDTM":"2023-09-24 02:41:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-24","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4009,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.5672,"AVALU":"U/L","BASE2":22.94313,"BASE":36.54245,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.37592,"PCHG2":-40.86593,"CHG":-22.97524,"PCHG":-62.87275,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-27 08:41:18","ADY":764,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-348","SUBJID":"id-348","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.3549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-21","TRTSDTM":"2020-09-23 08:41:18","TRTEDTM":"2023-09-24 02:41:18","TRT01SDTM":"2020-09-23 08:41:18","TRT01EDTM":"2022-09-23 20:41:18","TRT02SDTM":"2022-09-23 20:41:18","TRT02EDTM":"2023-09-24 02:41:18","AP01SDTM":"2020-09-23 08:41:18","AP01EDTM":"2022-09-23 20:41:18","AP02SDTM":"2022-09-23 20:41:18","AP02EDTM":"2023-09-24 02:41:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-24","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5454,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.91321,"AVALU":"U/L","BASE2":22.94313,"BASE":36.54245,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.02992,"PCHG2":-34.99922,"CHG":-21.62923,"PCHG":-59.18934,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-31 08:41:18","ADY":829,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-348","SUBJID":"id-348","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.3549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-21","TRTSDTM":"2020-09-23 08:41:18","TRTEDTM":"2023-09-24 02:41:18","TRT01SDTM":"2020-09-23 08:41:18","TRT01EDTM":"2022-09-23 20:41:18","TRT02SDTM":"2022-09-23 20:41:18","TRT02EDTM":"2023-09-24 02:41:18","AP01SDTM":"2020-09-23 08:41:18","AP01EDTM":"2022-09-23 20:41:18","AP02SDTM":"2022-09-23 20:41:18","AP02EDTM":"2023-09-24 02:41:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-24","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1721,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.10785,"AVALU":"U/L","BASE2":22.94313,"BASE":36.54245,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.16473,"PCHG2":18.15239,"CHG":-9.43459,"PCHG":-25.81817,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-24 08:41:18","ADY":1004,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-348","SUBJID":"id-348","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.3549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-21","TRTSDTM":"2020-09-23 08:41:18","TRTEDTM":"2023-09-24 02:41:18","TRT01SDTM":"2020-09-23 08:41:18","TRT01EDTM":"2022-09-23 20:41:18","TRT02SDTM":"2022-09-23 20:41:18","TRT02EDTM":"2023-09-24 02:41:18","AP01SDTM":"2020-09-23 08:41:18","AP01EDTM":"2022-09-23 20:41:18","AP02SDTM":"2022-09-23 20:41:18","AP02EDTM":"2023-09-24 02:41:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-24","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4376,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.04983,"AVALU":"mg/L","BASE2":9.04983,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-10-20 08:41:18","ADY":392,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-348","SUBJID":"id-348","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.3549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-21","TRTSDTM":"2020-09-23 08:41:18","TRTEDTM":"2023-09-24 02:41:18","TRT01SDTM":"2020-09-23 08:41:18","TRT01EDTM":"2022-09-23 20:41:18","TRT02SDTM":"2022-09-23 20:41:18","TRT02EDTM":"2023-09-24 02:41:18","AP01SDTM":"2020-09-23 08:41:18","AP01EDTM":"2022-09-23 20:41:18","AP02SDTM":"2022-09-23 20:41:18","AP02EDTM":"2023-09-24 02:41:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-24","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5284,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.03858,"AVALU":"mg/L","BASE2":9.04983,"BASE":7.03858,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.01125,"PCHG2":-22.22418,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-4","BTOXGR":"-4","ADTM":"2022-01-21 08:41:18","ADY":485,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-348","SUBJID":"id-348","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.3549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-21","TRTSDTM":"2020-09-23 08:41:18","TRTEDTM":"2023-09-24 02:41:18","TRT01SDTM":"2020-09-23 08:41:18","TRT01EDTM":"2022-09-23 20:41:18","TRT02SDTM":"2022-09-23 20:41:18","TRT02EDTM":"2023-09-24 02:41:18","AP01SDTM":"2020-09-23 08:41:18","AP01EDTM":"2022-09-23 20:41:18","AP02SDTM":"2022-09-23 20:41:18","AP02EDTM":"2023-09-24 02:41:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-24","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7324,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.08344,"AVALU":"mg/L","BASE2":9.04983,"BASE":7.03858,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0336,"PCHG2":0.37129,"CHG":2.04485,"PCHG":29.05205,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2022-04-17 08:41:18","ADY":571,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-348","SUBJID":"id-348","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.3549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-21","TRTSDTM":"2020-09-23 08:41:18","TRTEDTM":"2023-09-24 02:41:18","TRT01SDTM":"2020-09-23 08:41:18","TRT01EDTM":"2022-09-23 20:41:18","TRT02SDTM":"2022-09-23 20:41:18","TRT02EDTM":"2023-09-24 02:41:18","AP01SDTM":"2020-09-23 08:41:18","AP01EDTM":"2022-09-23 20:41:18","AP02SDTM":"2022-09-23 20:41:18","AP02EDTM":"2023-09-24 02:41:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-24","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":790,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.02515,"AVALU":"mg/L","BASE2":9.04983,"BASE":7.03858,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02469,"PCHG2":-0.27279,"CHG":1.98656,"PCHG":28.22393,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2022-06-09 08:41:18","ADY":624,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-348","SUBJID":"id-348","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.3549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-21","TRTSDTM":"2020-09-23 08:41:18","TRTEDTM":"2023-09-24 02:41:18","TRT01SDTM":"2020-09-23 08:41:18","TRT01EDTM":"2022-09-23 20:41:18","TRT02SDTM":"2022-09-23 20:41:18","TRT02EDTM":"2023-09-24 02:41:18","AP01SDTM":"2020-09-23 08:41:18","AP01EDTM":"2022-09-23 20:41:18","AP02SDTM":"2022-09-23 20:41:18","AP02EDTM":"2023-09-24 02:41:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-24","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1133,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.9999,"AVALU":"mg/L","BASE2":9.04983,"BASE":7.03858,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04993,"PCHG2":-0.55177,"CHG":1.96132,"PCHG":27.86524,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2022-10-27 08:41:18","ADY":764,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-348","SUBJID":"id-348","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.3549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-21","TRTSDTM":"2020-09-23 08:41:18","TRTEDTM":"2023-09-24 02:41:18","TRT01SDTM":"2020-09-23 08:41:18","TRT01EDTM":"2022-09-23 20:41:18","TRT02SDTM":"2022-09-23 20:41:18","TRT02EDTM":"2023-09-24 02:41:18","AP01SDTM":"2020-09-23 08:41:18","AP01EDTM":"2022-09-23 20:41:18","AP02SDTM":"2022-09-23 20:41:18","AP02EDTM":"2023-09-24 02:41:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-24","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":36,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.66779,"AVALU":"mg/L","BASE2":9.04983,"BASE":7.03858,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.61796,"PCHG2":6.82841,"CHG":2.62921,"PCHG":37.35427,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2022-12-31 08:41:18","ADY":829,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-348","SUBJID":"id-348","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.3549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-21","TRTSDTM":"2020-09-23 08:41:18","TRTEDTM":"2023-09-24 02:41:18","TRT01SDTM":"2020-09-23 08:41:18","TRT01EDTM":"2022-09-23 20:41:18","TRT02SDTM":"2022-09-23 20:41:18","TRT02EDTM":"2023-09-24 02:41:18","AP01SDTM":"2020-09-23 08:41:18","AP01EDTM":"2022-09-23 20:41:18","AP02SDTM":"2022-09-23 20:41:18","AP02EDTM":"2023-09-24 02:41:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-24","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7649,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.00194,"AVALU":"mg/L","BASE2":9.04983,"BASE":7.03858,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.95211,"PCHG2":21.57066,"CHG":3.96336,"PCHG":56.30908,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"2","BTOXGR":"-4","ADTM":"2023-06-24 08:41:18","ADY":1004,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-348","SUBJID":"id-348","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.3549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-21","TRTSDTM":"2020-09-23 08:41:18","TRTEDTM":"2023-09-24 02:41:18","TRT01SDTM":"2020-09-23 08:41:18","TRT01EDTM":"2022-09-23 20:41:18","TRT02SDTM":"2022-09-23 20:41:18","TRT02EDTM":"2023-09-24 02:41:18","AP01SDTM":"2020-09-23 08:41:18","AP01EDTM":"2022-09-23 20:41:18","AP02SDTM":"2022-09-23 20:41:18","AP02EDTM":"2023-09-24 02:41:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-24","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2244,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.64859,"AVALU":"g/L","BASE2":2.64859,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-20 08:41:18","ADY":392,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-348","SUBJID":"id-348","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.3549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-21","TRTSDTM":"2020-09-23 08:41:18","TRTEDTM":"2023-09-24 02:41:18","TRT01SDTM":"2020-09-23 08:41:18","TRT01EDTM":"2022-09-23 20:41:18","TRT02SDTM":"2022-09-23 20:41:18","TRT02EDTM":"2023-09-24 02:41:18","AP01SDTM":"2020-09-23 08:41:18","AP01EDTM":"2022-09-23 20:41:18","AP02SDTM":"2022-09-23 20:41:18","AP02EDTM":"2023-09-24 02:41:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-24","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2349,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78133,"AVALU":"g/L","BASE2":2.64859,"BASE":2.78133,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.13274,"PCHG2":5.01176,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-21 08:41:18","ADY":485,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-348","SUBJID":"id-348","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.3549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-21","TRTSDTM":"2020-09-23 08:41:18","TRTEDTM":"2023-09-24 02:41:18","TRT01SDTM":"2020-09-23 08:41:18","TRT01EDTM":"2022-09-23 20:41:18","TRT02SDTM":"2022-09-23 20:41:18","TRT02EDTM":"2023-09-24 02:41:18","AP01SDTM":"2020-09-23 08:41:18","AP01EDTM":"2022-09-23 20:41:18","AP02SDTM":"2022-09-23 20:41:18","AP02EDTM":"2023-09-24 02:41:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-24","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2123,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83762,"AVALU":"g/L","BASE2":2.64859,"BASE":2.78133,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18903,"PCHG2":7.13696,"CHG":0.05629,"PCHG":2.02377,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-17 08:41:18","ADY":571,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-348","SUBJID":"id-348","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.3549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-21","TRTSDTM":"2020-09-23 08:41:18","TRTEDTM":"2023-09-24 02:41:18","TRT01SDTM":"2020-09-23 08:41:18","TRT01EDTM":"2022-09-23 20:41:18","TRT02SDTM":"2022-09-23 20:41:18","TRT02EDTM":"2023-09-24 02:41:18","AP01SDTM":"2020-09-23 08:41:18","AP01EDTM":"2022-09-23 20:41:18","AP02SDTM":"2022-09-23 20:41:18","AP02EDTM":"2023-09-24 02:41:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-24","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":770,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97422,"AVALU":"g/L","BASE2":2.64859,"BASE":2.78133,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.32563,"PCHG2":12.29436,"CHG":0.19289,"PCHG":6.93504,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-09 08:41:18","ADY":624,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-348","SUBJID":"id-348","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.3549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-21","TRTSDTM":"2020-09-23 08:41:18","TRTEDTM":"2023-09-24 02:41:18","TRT01SDTM":"2020-09-23 08:41:18","TRT01EDTM":"2022-09-23 20:41:18","TRT02SDTM":"2022-09-23 20:41:18","TRT02EDTM":"2023-09-24 02:41:18","AP01SDTM":"2020-09-23 08:41:18","AP01EDTM":"2022-09-23 20:41:18","AP02SDTM":"2022-09-23 20:41:18","AP02EDTM":"2023-09-24 02:41:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-24","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6924,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91886,"AVALU":"g/L","BASE2":2.64859,"BASE":2.78133,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.27027,"PCHG2":10.20436,"CHG":0.13753,"PCHG":4.94478,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-27 08:41:18","ADY":764,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-348","SUBJID":"id-348","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.3549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-21","TRTSDTM":"2020-09-23 08:41:18","TRTEDTM":"2023-09-24 02:41:18","TRT01SDTM":"2020-09-23 08:41:18","TRT01EDTM":"2022-09-23 20:41:18","TRT02SDTM":"2022-09-23 20:41:18","TRT02EDTM":"2023-09-24 02:41:18","AP01SDTM":"2020-09-23 08:41:18","AP01EDTM":"2022-09-23 20:41:18","AP02SDTM":"2022-09-23 20:41:18","AP02EDTM":"2023-09-24 02:41:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-24","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6528,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02546,"AVALU":"g/L","BASE2":2.64859,"BASE":2.78133,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.37687,"PCHG2":14.22912,"CHG":0.24413,"PCHG":8.77746,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-12-31 08:41:18","ADY":829,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-348","SUBJID":"id-348","SITEID":"CHN-5","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":4.3549,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-21","TRTSDTM":"2020-09-23 08:41:18","TRTEDTM":"2023-09-24 02:41:18","TRT01SDTM":"2020-09-23 08:41:18","TRT01EDTM":"2022-09-23 20:41:18","TRT02SDTM":"2022-09-23 20:41:18","TRT02EDTM":"2023-09-24 02:41:18","AP01SDTM":"2020-09-23 08:41:18","AP01EDTM":"2022-09-23 20:41:18","AP02SDTM":"2022-09-23 20:41:18","AP02EDTM":"2023-09-24 02:41:18","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-24","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2029,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97019,"AVALU":"g/L","BASE2":2.64859,"BASE":2.78133,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.3216,"PCHG2":12.14231,"CHG":0.18886,"PCHG":6.79024,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-24 08:41:18","ADY":1004,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-83","SUBJID":"id-83","SITEID":"CHN-5","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.60956,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 10:03:25","TRTEDTM":"2022-02-17 09:03:28","TRT01SDTM":"2019-10-08 10:03:25","TRT01EDTM":"2021-02-17 03:03:28","TRT02SDTM":"2021-02-17 03:03:28","TRT02EDTM":"2022-02-17 09:03:28","AP01SDTM":"2019-10-08 10:03:25","AP01EDTM":"2021-02-17 03:03:28","AP02SDTM":"2021-02-17 03:03:28","AP02EDTM":"2022-02-17 09:03:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-02","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":730,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.92619,"AVALU":"U/L","BASE2":15.92619,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-14 10:03:25","ADY":67,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-83","SUBJID":"id-83","SITEID":"CHN-5","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.60956,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 10:03:25","TRTEDTM":"2022-02-17 09:03:28","TRT01SDTM":"2019-10-08 10:03:25","TRT01EDTM":"2021-02-17 03:03:28","TRT02SDTM":"2021-02-17 03:03:28","TRT02EDTM":"2022-02-17 09:03:28","AP01SDTM":"2019-10-08 10:03:25","AP01EDTM":"2021-02-17 03:03:28","AP02SDTM":"2021-02-17 03:03:28","AP02EDTM":"2022-02-17 09:03:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-02","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4793,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.8448,"AVALU":"U/L","BASE2":15.92619,"BASE":17.8448,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.91861,"PCHG2":12.04689,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-06 10:03:25","ADY":242,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-83","SUBJID":"id-83","SITEID":"CHN-5","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.60956,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 10:03:25","TRTEDTM":"2022-02-17 09:03:28","TRT01SDTM":"2019-10-08 10:03:25","TRT01EDTM":"2021-02-17 03:03:28","TRT02SDTM":"2021-02-17 03:03:28","TRT02EDTM":"2022-02-17 09:03:28","AP01SDTM":"2019-10-08 10:03:25","AP01EDTM":"2021-02-17 03:03:28","AP02SDTM":"2021-02-17 03:03:28","AP02EDTM":"2022-02-17 09:03:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-02","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3972,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.87361,"AVALU":"U/L","BASE2":15.92619,"BASE":17.8448,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.94742,"PCHG2":75.01743,"CHG":10.02881,"PCHG":56.20018,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-28 10:03:25","ADY":325,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-83","SUBJID":"id-83","SITEID":"CHN-5","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.60956,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 10:03:25","TRTEDTM":"2022-02-17 09:03:28","TRT01SDTM":"2019-10-08 10:03:25","TRT01EDTM":"2021-02-17 03:03:28","TRT02SDTM":"2021-02-17 03:03:28","TRT02EDTM":"2022-02-17 09:03:28","AP01SDTM":"2019-10-08 10:03:25","AP01EDTM":"2021-02-17 03:03:28","AP02SDTM":"2021-02-17 03:03:28","AP02EDTM":"2022-02-17 09:03:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-02","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":994,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.20827,"AVALU":"U/L","BASE2":15.92619,"BASE":17.8448,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.28208,"PCHG2":83.39769,"CHG":11.36347,"PCHG":63.67942,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-23 10:03:25","ADY":442,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-83","SUBJID":"id-83","SITEID":"CHN-5","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.60956,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 10:03:25","TRTEDTM":"2022-02-17 09:03:28","TRT01SDTM":"2019-10-08 10:03:25","TRT01EDTM":"2021-02-17 03:03:28","TRT02SDTM":"2021-02-17 03:03:28","TRT02EDTM":"2022-02-17 09:03:28","AP01SDTM":"2019-10-08 10:03:25","AP01EDTM":"2021-02-17 03:03:28","AP02SDTM":"2021-02-17 03:03:28","AP02EDTM":"2022-02-17 09:03:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-02","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":672,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.03518,"AVALU":"U/L","BASE2":15.92619,"BASE":17.8448,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.10899,"PCHG2":69.75294,"CHG":9.19038,"PCHG":51.5017,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-27 10:03:25","ADY":536,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-83","SUBJID":"id-83","SITEID":"CHN-5","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.60956,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 10:03:25","TRTEDTM":"2022-02-17 09:03:28","TRT01SDTM":"2019-10-08 10:03:25","TRT01EDTM":"2021-02-17 03:03:28","TRT02SDTM":"2021-02-17 03:03:28","TRT02EDTM":"2022-02-17 09:03:28","AP01SDTM":"2019-10-08 10:03:25","AP01EDTM":"2021-02-17 03:03:28","AP02SDTM":"2021-02-17 03:03:28","AP02EDTM":"2022-02-17 09:03:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-02","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3023,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.45235,"AVALU":"U/L","BASE2":15.92619,"BASE":17.8448,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.52616,"PCHG2":28.41961,"CHG":2.60755,"PCHG":14.61239,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-25 10:03:25","ADY":656,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-83","SUBJID":"id-83","SITEID":"CHN-5","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.60956,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 10:03:25","TRTEDTM":"2022-02-17 09:03:28","TRT01SDTM":"2019-10-08 10:03:25","TRT01EDTM":"2021-02-17 03:03:28","TRT02SDTM":"2021-02-17 03:03:28","TRT02EDTM":"2022-02-17 09:03:28","AP01SDTM":"2019-10-08 10:03:25","AP01EDTM":"2021-02-17 03:03:28","AP02SDTM":"2021-02-17 03:03:28","AP02EDTM":"2022-02-17 09:03:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-02","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":930,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.36994,"AVALU":"U/L","BASE2":15.92619,"BASE":17.8448,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.44375,"PCHG2":103.24969,"CHG":14.52513,"PCHG":81.397,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-12 10:03:25","ADY":705,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-83","SUBJID":"id-83","SITEID":"CHN-5","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.60956,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 10:03:25","TRTEDTM":"2022-02-17 09:03:28","TRT01SDTM":"2019-10-08 10:03:25","TRT01EDTM":"2021-02-17 03:03:28","TRT02SDTM":"2021-02-17 03:03:28","TRT02EDTM":"2022-02-17 09:03:28","AP01SDTM":"2019-10-08 10:03:25","AP01EDTM":"2021-02-17 03:03:28","AP02SDTM":"2021-02-17 03:03:28","AP02EDTM":"2022-02-17 09:03:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-02","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6845,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.91252,"AVALU":"mg/L","BASE2":9.91252,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-14 10:03:25","ADY":67,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-83","SUBJID":"id-83","SITEID":"CHN-5","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.60956,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 10:03:25","TRTEDTM":"2022-02-17 09:03:28","TRT01SDTM":"2019-10-08 10:03:25","TRT01EDTM":"2021-02-17 03:03:28","TRT02SDTM":"2021-02-17 03:03:28","TRT02EDTM":"2022-02-17 09:03:28","AP01SDTM":"2019-10-08 10:03:25","AP01EDTM":"2021-02-17 03:03:28","AP02SDTM":"2021-02-17 03:03:28","AP02EDTM":"2022-02-17 09:03:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-02","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4708,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.94889,"AVALU":"mg/L","BASE2":9.91252,"BASE":8.94889,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.96363,"PCHG2":-9.72132,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-06 10:03:25","ADY":242,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-83","SUBJID":"id-83","SITEID":"CHN-5","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.60956,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 10:03:25","TRTEDTM":"2022-02-17 09:03:28","TRT01SDTM":"2019-10-08 10:03:25","TRT01EDTM":"2021-02-17 03:03:28","TRT02SDTM":"2021-02-17 03:03:28","TRT02EDTM":"2022-02-17 09:03:28","AP01SDTM":"2019-10-08 10:03:25","AP01EDTM":"2021-02-17 03:03:28","AP02SDTM":"2021-02-17 03:03:28","AP02EDTM":"2022-02-17 09:03:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-02","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3709,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.3253,"AVALU":"mg/L","BASE2":9.91252,"BASE":8.94889,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.58722,"PCHG2":-5.92401,"CHG":0.37641,"PCHG":4.20621,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-28 10:03:25","ADY":325,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-83","SUBJID":"id-83","SITEID":"CHN-5","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.60956,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 10:03:25","TRTEDTM":"2022-02-17 09:03:28","TRT01SDTM":"2019-10-08 10:03:25","TRT01EDTM":"2021-02-17 03:03:28","TRT02SDTM":"2021-02-17 03:03:28","TRT02EDTM":"2022-02-17 09:03:28","AP01SDTM":"2019-10-08 10:03:25","AP01EDTM":"2021-02-17 03:03:28","AP02SDTM":"2021-02-17 03:03:28","AP02EDTM":"2022-02-17 09:03:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-02","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2819,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.82585,"AVALU":"mg/L","BASE2":9.91252,"BASE":8.94889,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.08667,"PCHG2":-21.05082,"CHG":-1.12304,"PCHG":-12.54947,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-12-23 10:03:25","ADY":442,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-83","SUBJID":"id-83","SITEID":"CHN-5","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.60956,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 10:03:25","TRTEDTM":"2022-02-17 09:03:28","TRT01SDTM":"2019-10-08 10:03:25","TRT01EDTM":"2021-02-17 03:03:28","TRT02SDTM":"2021-02-17 03:03:28","TRT02EDTM":"2022-02-17 09:03:28","AP01SDTM":"2019-10-08 10:03:25","AP01EDTM":"2021-02-17 03:03:28","AP02SDTM":"2021-02-17 03:03:28","AP02EDTM":"2022-02-17 09:03:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-02","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5447,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.5369,"AVALU":"mg/L","BASE2":9.91252,"BASE":8.94889,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.37562,"PCHG2":-23.96582,"CHG":-1.41199,"PCHG":-15.77836,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-03-27 10:03:25","ADY":536,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-83","SUBJID":"id-83","SITEID":"CHN-5","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.60956,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 10:03:25","TRTEDTM":"2022-02-17 09:03:28","TRT01SDTM":"2019-10-08 10:03:25","TRT01EDTM":"2021-02-17 03:03:28","TRT02SDTM":"2021-02-17 03:03:28","TRT02EDTM":"2022-02-17 09:03:28","AP01SDTM":"2019-10-08 10:03:25","AP01EDTM":"2021-02-17 03:03:28","AP02SDTM":"2021-02-17 03:03:28","AP02EDTM":"2022-02-17 09:03:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-02","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1339,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.1537,"AVALU":"mg/L","BASE2":9.91252,"BASE":8.94889,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.24118,"PCHG2":2.43307,"CHG":1.20481,"PCHG":13.46319,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-07-25 10:03:25","ADY":656,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-83","SUBJID":"id-83","SITEID":"CHN-5","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.60956,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 10:03:25","TRTEDTM":"2022-02-17 09:03:28","TRT01SDTM":"2019-10-08 10:03:25","TRT01EDTM":"2021-02-17 03:03:28","TRT02SDTM":"2021-02-17 03:03:28","TRT02EDTM":"2022-02-17 09:03:28","AP01SDTM":"2019-10-08 10:03:25","AP01EDTM":"2021-02-17 03:03:28","AP02SDTM":"2021-02-17 03:03:28","AP02EDTM":"2022-02-17 09:03:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-02","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6534,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.02053,"AVALU":"mg/L","BASE2":9.91252,"BASE":8.94889,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.89199,"PCHG2":-8.9986,"CHG":0.07164,"PCHG":0.80054,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-12 10:03:25","ADY":705,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-83","SUBJID":"id-83","SITEID":"CHN-5","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.60956,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 10:03:25","TRTEDTM":"2022-02-17 09:03:28","TRT01SDTM":"2019-10-08 10:03:25","TRT01EDTM":"2021-02-17 03:03:28","TRT02SDTM":"2021-02-17 03:03:28","TRT02EDTM":"2022-02-17 09:03:28","AP01SDTM":"2019-10-08 10:03:25","AP01EDTM":"2021-02-17 03:03:28","AP02SDTM":"2021-02-17 03:03:28","AP02EDTM":"2022-02-17 09:03:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-02","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6165,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93344,"AVALU":"g/L","BASE2":2.93344,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-14 10:03:25","ADY":67,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-83","SUBJID":"id-83","SITEID":"CHN-5","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.60956,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 10:03:25","TRTEDTM":"2022-02-17 09:03:28","TRT01SDTM":"2019-10-08 10:03:25","TRT01EDTM":"2021-02-17 03:03:28","TRT02SDTM":"2021-02-17 03:03:28","TRT02EDTM":"2022-02-17 09:03:28","AP01SDTM":"2019-10-08 10:03:25","AP01EDTM":"2021-02-17 03:03:28","AP02SDTM":"2021-02-17 03:03:28","AP02EDTM":"2022-02-17 09:03:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-02","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3681,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92914,"AVALU":"g/L","BASE2":2.93344,"BASE":2.92914,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.00431,"PCHG2":-0.1468,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-06 10:03:25","ADY":242,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-83","SUBJID":"id-83","SITEID":"CHN-5","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.60956,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 10:03:25","TRTEDTM":"2022-02-17 09:03:28","TRT01SDTM":"2019-10-08 10:03:25","TRT01EDTM":"2021-02-17 03:03:28","TRT02SDTM":"2021-02-17 03:03:28","TRT02EDTM":"2022-02-17 09:03:28","AP01SDTM":"2019-10-08 10:03:25","AP01EDTM":"2021-02-17 03:03:28","AP02SDTM":"2021-02-17 03:03:28","AP02EDTM":"2022-02-17 09:03:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-02","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2035,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8012,"AVALU":"g/L","BASE2":2.93344,"BASE":2.92914,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13224,"PCHG2":-4.50814,"CHG":-0.12794,"PCHG":-4.36776,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-28 10:03:25","ADY":325,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-83","SUBJID":"id-83","SITEID":"CHN-5","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.60956,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 10:03:25","TRTEDTM":"2022-02-17 09:03:28","TRT01SDTM":"2019-10-08 10:03:25","TRT01EDTM":"2021-02-17 03:03:28","TRT02SDTM":"2021-02-17 03:03:28","TRT02EDTM":"2022-02-17 09:03:28","AP01SDTM":"2019-10-08 10:03:25","AP01EDTM":"2021-02-17 03:03:28","AP02SDTM":"2021-02-17 03:03:28","AP02EDTM":"2022-02-17 09:03:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-02","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4923,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80904,"AVALU":"g/L","BASE2":2.93344,"BASE":2.92914,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12441,"PCHG2":-4.24101,"CHG":-0.1201,"PCHG":-4.10023,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-23 10:03:25","ADY":442,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-83","SUBJID":"id-83","SITEID":"CHN-5","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.60956,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 10:03:25","TRTEDTM":"2022-02-17 09:03:28","TRT01SDTM":"2019-10-08 10:03:25","TRT01EDTM":"2021-02-17 03:03:28","TRT02SDTM":"2021-02-17 03:03:28","TRT02EDTM":"2022-02-17 09:03:28","AP01SDTM":"2019-10-08 10:03:25","AP01EDTM":"2021-02-17 03:03:28","AP02SDTM":"2021-02-17 03:03:28","AP02EDTM":"2022-02-17 09:03:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-02","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5461,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85395,"AVALU":"g/L","BASE2":2.93344,"BASE":2.92914,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0795,"PCHG2":-2.70996,"CHG":-0.07519,"PCHG":-2.56693,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-27 10:03:25","ADY":536,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-83","SUBJID":"id-83","SITEID":"CHN-5","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.60956,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 10:03:25","TRTEDTM":"2022-02-17 09:03:28","TRT01SDTM":"2019-10-08 10:03:25","TRT01EDTM":"2021-02-17 03:03:28","TRT02SDTM":"2021-02-17 03:03:28","TRT02EDTM":"2022-02-17 09:03:28","AP01SDTM":"2019-10-08 10:03:25","AP01EDTM":"2021-02-17 03:03:28","AP02SDTM":"2021-02-17 03:03:28","AP02EDTM":"2022-02-17 09:03:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-02","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6762,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94069,"AVALU":"g/L","BASE2":2.93344,"BASE":2.92914,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00725,"PCHG2":0.24716,"CHG":0.01156,"PCHG":0.39453,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-25 10:03:25","ADY":656,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-5-id-83","SUBJID":"id-83","SITEID":"CHN-5","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-5","INVNAM":"Dr. CHN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.60956,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-08","TRTSDTM":"2019-10-08 10:03:25","TRTEDTM":"2022-02-17 09:03:28","TRT01SDTM":"2019-10-08 10:03:25","TRT01EDTM":"2021-02-17 03:03:28","TRT02SDTM":"2021-02-17 03:03:28","TRT02EDTM":"2022-02-17 09:03:28","AP01SDTM":"2019-10-08 10:03:25","AP01EDTM":"2021-02-17 03:03:28","AP02SDTM":"2021-02-17 03:03:28","AP02EDTM":"2022-02-17 09:03:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-02","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3349,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7238,"AVALU":"g/L","BASE2":2.93344,"BASE":2.92914,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20965,"PCHG2":-7.14676,"CHG":-0.20534,"PCHG":-7.01026,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-12 10:03:25","ADY":705,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-248","SUBJID":"id-248","SITEID":"CHN-6","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.11272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 00:59:20","TRTEDTM":"2022-02-18 13:27:57","TRT01SDTM":"2020-11-17 00:59:20","TRT01EDTM":"2021-02-18 07:27:57","TRT02SDTM":"2021-02-18 07:27:57","TRT02EDTM":"2022-02-18 13:27:57","AP01SDTM":"2020-11-17 00:59:20","AP01EDTM":"2021-02-18 07:27:57","AP02SDTM":"2021-02-18 07:27:57","AP02EDTM":"2022-02-18 13:27:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":459,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":488,"ADTHAUT":"No","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7275,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":36.87474,"AVALU":"U/L","BASE2":36.87474,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-26 00:59:20","ADY":39,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-248","SUBJID":"id-248","SITEID":"CHN-6","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.11272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 00:59:20","TRTEDTM":"2022-02-18 13:27:57","TRT01SDTM":"2020-11-17 00:59:20","TRT01EDTM":"2021-02-18 07:27:57","TRT02SDTM":"2021-02-18 07:27:57","TRT02EDTM":"2022-02-18 13:27:57","AP01SDTM":"2020-11-17 00:59:20","AP01EDTM":"2021-02-18 07:27:57","AP02SDTM":"2021-02-18 07:27:57","AP02EDTM":"2022-02-18 13:27:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":459,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":488,"ADTHAUT":"No","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7480,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.74565,"AVALU":"U/L","BASE2":36.87474,"BASE":22.74565,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-14.12909,"PCHG2":-38.31645,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-25 00:59:20","ADY":189,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-248","SUBJID":"id-248","SITEID":"CHN-6","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.11272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 00:59:20","TRTEDTM":"2022-02-18 13:27:57","TRT01SDTM":"2020-11-17 00:59:20","TRT01EDTM":"2021-02-18 07:27:57","TRT02SDTM":"2021-02-18 07:27:57","TRT02EDTM":"2022-02-18 13:27:57","AP01SDTM":"2020-11-17 00:59:20","AP01EDTM":"2021-02-18 07:27:57","AP02SDTM":"2021-02-18 07:27:57","AP02EDTM":"2022-02-18 13:27:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":459,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":488,"ADTHAUT":"No","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3565,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.74677,"AVALU":"U/L","BASE2":36.87474,"BASE":22.74565,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-29.12797,"PCHG2":-78.99166,"CHG":-14.99888,"PCHG":-65.94175,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-02 00:59:20","ADY":197,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-248","SUBJID":"id-248","SITEID":"CHN-6","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.11272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 00:59:20","TRTEDTM":"2022-02-18 13:27:57","TRT01SDTM":"2020-11-17 00:59:20","TRT01EDTM":"2021-02-18 07:27:57","TRT02SDTM":"2021-02-18 07:27:57","TRT02EDTM":"2022-02-18 13:27:57","AP01SDTM":"2020-11-17 00:59:20","AP01EDTM":"2021-02-18 07:27:57","AP02SDTM":"2021-02-18 07:27:57","AP02EDTM":"2022-02-18 13:27:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":459,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":488,"ADTHAUT":"No","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4740,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.81784,"AVALU":"U/L","BASE2":36.87474,"BASE":22.74565,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.0569,"PCHG2":-46.25632,"CHG":-2.92781,"PCHG":-12.87195,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-19 00:59:20","ADY":306,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-248","SUBJID":"id-248","SITEID":"CHN-6","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.11272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 00:59:20","TRTEDTM":"2022-02-18 13:27:57","TRT01SDTM":"2020-11-17 00:59:20","TRT01EDTM":"2021-02-18 07:27:57","TRT02SDTM":"2021-02-18 07:27:57","TRT02EDTM":"2022-02-18 13:27:57","AP01SDTM":"2020-11-17 00:59:20","AP01EDTM":"2021-02-18 07:27:57","AP02SDTM":"2021-02-18 07:27:57","AP02EDTM":"2022-02-18 13:27:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":459,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":488,"ADTHAUT":"No","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6447,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.94221,"AVALU":"U/L","BASE2":36.87474,"BASE":22.74565,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-30.93254,"PCHG2":-83.88543,"CHG":-16.80345,"PCHG":-73.87542,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-11-26 00:59:20","ADY":374,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-248","SUBJID":"id-248","SITEID":"CHN-6","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.11272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 00:59:20","TRTEDTM":"2022-02-18 13:27:57","TRT01SDTM":"2020-11-17 00:59:20","TRT01EDTM":"2021-02-18 07:27:57","TRT02SDTM":"2021-02-18 07:27:57","TRT02EDTM":"2022-02-18 13:27:57","AP01SDTM":"2020-11-17 00:59:20","AP01EDTM":"2021-02-18 07:27:57","AP02SDTM":"2021-02-18 07:27:57","AP02EDTM":"2022-02-18 13:27:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":459,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":488,"ADTHAUT":"No","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2988,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.23059,"AVALU":"U/L","BASE2":36.87474,"BASE":22.74565,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-30.64416,"PCHG2":-83.10337,"CHG":-16.51506,"PCHG":-72.60756,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-12-12 00:59:20","ADY":390,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-248","SUBJID":"id-248","SITEID":"CHN-6","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.11272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 00:59:20","TRTEDTM":"2022-02-18 13:27:57","TRT01SDTM":"2020-11-17 00:59:20","TRT01EDTM":"2021-02-18 07:27:57","TRT02SDTM":"2021-02-18 07:27:57","TRT02EDTM":"2022-02-18 13:27:57","AP01SDTM":"2020-11-17 00:59:20","AP01EDTM":"2021-02-18 07:27:57","AP02SDTM":"2021-02-18 07:27:57","AP02EDTM":"2022-02-18 13:27:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":459,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":488,"ADTHAUT":"No","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2601,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.96465,"AVALU":"U/L","BASE2":36.87474,"BASE":22.74565,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-26.91009,"PCHG2":-72.97703,"CHG":-12.781,"PCHG":-56.19096,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-06 00:59:20","ADY":415,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-248","SUBJID":"id-248","SITEID":"CHN-6","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.11272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 00:59:20","TRTEDTM":"2022-02-18 13:27:57","TRT01SDTM":"2020-11-17 00:59:20","TRT01EDTM":"2021-02-18 07:27:57","TRT02SDTM":"2021-02-18 07:27:57","TRT02EDTM":"2022-02-18 13:27:57","AP01SDTM":"2020-11-17 00:59:20","AP01EDTM":"2021-02-18 07:27:57","AP02SDTM":"2021-02-18 07:27:57","AP02EDTM":"2022-02-18 13:27:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":459,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":488,"ADTHAUT":"No","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7509,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.28365,"AVALU":"mg/L","BASE2":8.28365,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-12-26 00:59:20","ADY":39,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-248","SUBJID":"id-248","SITEID":"CHN-6","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.11272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 00:59:20","TRTEDTM":"2022-02-18 13:27:57","TRT01SDTM":"2020-11-17 00:59:20","TRT01EDTM":"2021-02-18 07:27:57","TRT02SDTM":"2021-02-18 07:27:57","TRT02EDTM":"2022-02-18 13:27:57","AP01SDTM":"2020-11-17 00:59:20","AP01EDTM":"2021-02-18 07:27:57","AP02SDTM":"2021-02-18 07:27:57","AP02EDTM":"2022-02-18 13:27:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":459,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":488,"ADTHAUT":"No","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7004,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.08774,"AVALU":"mg/L","BASE2":8.28365,"BASE":7.08774,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.19591,"PCHG2":-14.43698,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2021-05-25 00:59:20","ADY":189,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-248","SUBJID":"id-248","SITEID":"CHN-6","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.11272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 00:59:20","TRTEDTM":"2022-02-18 13:27:57","TRT01SDTM":"2020-11-17 00:59:20","TRT01EDTM":"2021-02-18 07:27:57","TRT02SDTM":"2021-02-18 07:27:57","TRT02EDTM":"2022-02-18 13:27:57","AP01SDTM":"2020-11-17 00:59:20","AP01EDTM":"2021-02-18 07:27:57","AP02SDTM":"2021-02-18 07:27:57","AP02EDTM":"2022-02-18 13:27:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":459,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":488,"ADTHAUT":"No","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6108,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.71713,"AVALU":"mg/L","BASE2":8.28365,"BASE":7.08774,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.43348,"PCHG2":5.23296,"CHG":1.62939,"PCHG":22.98883,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-06-02 00:59:20","ADY":197,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-248","SUBJID":"id-248","SITEID":"CHN-6","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.11272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 00:59:20","TRTEDTM":"2022-02-18 13:27:57","TRT01SDTM":"2020-11-17 00:59:20","TRT01EDTM":"2021-02-18 07:27:57","TRT02SDTM":"2021-02-18 07:27:57","TRT02EDTM":"2022-02-18 13:27:57","AP01SDTM":"2020-11-17 00:59:20","AP01EDTM":"2021-02-18 07:27:57","AP02SDTM":"2021-02-18 07:27:57","AP02EDTM":"2022-02-18 13:27:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":459,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":488,"ADTHAUT":"No","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7197,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.73777,"AVALU":"mg/L","BASE2":8.28365,"BASE":7.08774,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.45411,"PCHG2":5.48204,"CHG":1.65002,"PCHG":23.27994,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-09-19 00:59:20","ADY":306,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-248","SUBJID":"id-248","SITEID":"CHN-6","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.11272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 00:59:20","TRTEDTM":"2022-02-18 13:27:57","TRT01SDTM":"2020-11-17 00:59:20","TRT01EDTM":"2021-02-18 07:27:57","TRT02SDTM":"2021-02-18 07:27:57","TRT02EDTM":"2022-02-18 13:27:57","AP01SDTM":"2020-11-17 00:59:20","AP01EDTM":"2021-02-18 07:27:57","AP02SDTM":"2021-02-18 07:27:57","AP02EDTM":"2022-02-18 13:27:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":459,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":488,"ADTHAUT":"No","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2922,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.44147,"AVALU":"mg/L","BASE2":8.28365,"BASE":7.08774,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.15782,"PCHG2":13.97714,"CHG":2.35373,"PCHG":33.20841,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-11-26 00:59:20","ADY":374,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-248","SUBJID":"id-248","SITEID":"CHN-6","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.11272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 00:59:20","TRTEDTM":"2022-02-18 13:27:57","TRT01SDTM":"2020-11-17 00:59:20","TRT01EDTM":"2021-02-18 07:27:57","TRT02SDTM":"2021-02-18 07:27:57","TRT02EDTM":"2022-02-18 13:27:57","AP01SDTM":"2020-11-17 00:59:20","AP01EDTM":"2021-02-18 07:27:57","AP02SDTM":"2021-02-18 07:27:57","AP02EDTM":"2022-02-18 13:27:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":459,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":488,"ADTHAUT":"No","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6188,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.51124,"AVALU":"mg/L","BASE2":8.28365,"BASE":7.08774,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.22759,"PCHG2":2.74747,"CHG":1.4235,"PCHG":20.08397,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-12-12 00:59:20","ADY":390,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-248","SUBJID":"id-248","SITEID":"CHN-6","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.11272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 00:59:20","TRTEDTM":"2022-02-18 13:27:57","TRT01SDTM":"2020-11-17 00:59:20","TRT01EDTM":"2021-02-18 07:27:57","TRT02SDTM":"2021-02-18 07:27:57","TRT02EDTM":"2022-02-18 13:27:57","AP01SDTM":"2020-11-17 00:59:20","AP01EDTM":"2021-02-18 07:27:57","AP02SDTM":"2021-02-18 07:27:57","AP02EDTM":"2022-02-18 13:27:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":459,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":488,"ADTHAUT":"No","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":465,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.71897,"AVALU":"mg/L","BASE2":8.28365,"BASE":7.08774,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.43531,"PCHG2":17.32707,"CHG":2.63122,"PCHG":37.12357,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-01-06 00:59:20","ADY":415,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-248","SUBJID":"id-248","SITEID":"CHN-6","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.11272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 00:59:20","TRTEDTM":"2022-02-18 13:27:57","TRT01SDTM":"2020-11-17 00:59:20","TRT01EDTM":"2021-02-18 07:27:57","TRT02SDTM":"2021-02-18 07:27:57","TRT02EDTM":"2022-02-18 13:27:57","AP01SDTM":"2020-11-17 00:59:20","AP01EDTM":"2021-02-18 07:27:57","AP02SDTM":"2021-02-18 07:27:57","AP02EDTM":"2022-02-18 13:27:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":459,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":488,"ADTHAUT":"No","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7194,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99483,"AVALU":"g/L","BASE2":2.99483,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-26 00:59:20","ADY":39,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-248","SUBJID":"id-248","SITEID":"CHN-6","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.11272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 00:59:20","TRTEDTM":"2022-02-18 13:27:57","TRT01SDTM":"2020-11-17 00:59:20","TRT01EDTM":"2021-02-18 07:27:57","TRT02SDTM":"2021-02-18 07:27:57","TRT02EDTM":"2022-02-18 13:27:57","AP01SDTM":"2020-11-17 00:59:20","AP01EDTM":"2021-02-18 07:27:57","AP02SDTM":"2021-02-18 07:27:57","AP02EDTM":"2022-02-18 13:27:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":459,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":488,"ADTHAUT":"No","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4631,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80972,"AVALU":"g/L","BASE2":2.99483,"BASE":2.80972,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.18511,"PCHG2":-6.18093,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-25 00:59:20","ADY":189,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-248","SUBJID":"id-248","SITEID":"CHN-6","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.11272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 00:59:20","TRTEDTM":"2022-02-18 13:27:57","TRT01SDTM":"2020-11-17 00:59:20","TRT01EDTM":"2021-02-18 07:27:57","TRT02SDTM":"2021-02-18 07:27:57","TRT02EDTM":"2022-02-18 13:27:57","AP01SDTM":"2020-11-17 00:59:20","AP01EDTM":"2021-02-18 07:27:57","AP02SDTM":"2021-02-18 07:27:57","AP02EDTM":"2022-02-18 13:27:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":459,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":488,"ADTHAUT":"No","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3434,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00165,"AVALU":"g/L","BASE2":2.99483,"BASE":2.80972,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00682,"PCHG2":0.22778,"CHG":0.19193,"PCHG":6.83092,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-06-02 00:59:20","ADY":197,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-248","SUBJID":"id-248","SITEID":"CHN-6","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.11272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 00:59:20","TRTEDTM":"2022-02-18 13:27:57","TRT01SDTM":"2020-11-17 00:59:20","TRT01EDTM":"2021-02-18 07:27:57","TRT02SDTM":"2021-02-18 07:27:57","TRT02EDTM":"2022-02-18 13:27:57","AP01SDTM":"2020-11-17 00:59:20","AP01EDTM":"2021-02-18 07:27:57","AP02SDTM":"2021-02-18 07:27:57","AP02EDTM":"2022-02-18 13:27:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":459,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":488,"ADTHAUT":"No","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6028,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98742,"AVALU":"g/L","BASE2":2.99483,"BASE":2.80972,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00741,"PCHG2":-0.24741,"CHG":0.1777,"PCHG":6.32442,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-19 00:59:20","ADY":306,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-248","SUBJID":"id-248","SITEID":"CHN-6","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.11272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 00:59:20","TRTEDTM":"2022-02-18 13:27:57","TRT01SDTM":"2020-11-17 00:59:20","TRT01EDTM":"2021-02-18 07:27:57","TRT02SDTM":"2021-02-18 07:27:57","TRT02EDTM":"2022-02-18 13:27:57","AP01SDTM":"2020-11-17 00:59:20","AP01EDTM":"2021-02-18 07:27:57","AP02SDTM":"2021-02-18 07:27:57","AP02EDTM":"2022-02-18 13:27:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":459,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":488,"ADTHAUT":"No","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":501,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91408,"AVALU":"g/L","BASE2":2.99483,"BASE":2.80972,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08075,"PCHG2":-2.69634,"CHG":0.10436,"PCHG":3.71416,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-26 00:59:20","ADY":374,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-248","SUBJID":"id-248","SITEID":"CHN-6","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.11272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 00:59:20","TRTEDTM":"2022-02-18 13:27:57","TRT01SDTM":"2020-11-17 00:59:20","TRT01EDTM":"2021-02-18 07:27:57","TRT02SDTM":"2021-02-18 07:27:57","TRT02EDTM":"2022-02-18 13:27:57","AP01SDTM":"2020-11-17 00:59:20","AP01EDTM":"2021-02-18 07:27:57","AP02SDTM":"2021-02-18 07:27:57","AP02EDTM":"2022-02-18 13:27:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":459,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":488,"ADTHAUT":"No","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2376,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00893,"AVALU":"g/L","BASE2":2.99483,"BASE":2.80972,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01409,"PCHG2":0.47057,"CHG":0.1992,"PCHG":7.08971,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-12-12 00:59:20","ADY":390,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-248","SUBJID":"id-248","SITEID":"CHN-6","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.11272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 00:59:20","TRTEDTM":"2022-02-18 13:27:57","TRT01SDTM":"2020-11-17 00:59:20","TRT01EDTM":"2021-02-18 07:27:57","TRT02SDTM":"2021-02-18 07:27:57","TRT02EDTM":"2022-02-18 13:27:57","AP01SDTM":"2020-11-17 00:59:20","AP01EDTM":"2021-02-18 07:27:57","AP02SDTM":"2021-02-18 07:27:57","AP02EDTM":"2022-02-18 13:27:57","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":459,"DCSREAS":"DEATH","DTHDT":"2022-03-21","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":31,"LDDTHGR1":">30","LSTALVDT":"2022-03-21","DTHADY":488,"ADTHAUT":"No","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3002,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.12759,"AVALU":"g/L","BASE2":2.99483,"BASE":2.80972,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13276,"PCHG2":4.43292,"CHG":0.31787,"PCHG":11.3131,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-01-06 00:59:20","ADY":415,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-30","SUBJID":"id-30","SITEID":"CHN-6","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":12.22076,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 12:54:31","TRTEDTM":"2022-02-14 04:32:24","TRT01SDTM":"2020-08-24 12:54:31","TRT01EDTM":"2021-02-13 22:32:24","TRT02SDTM":"2021-02-13 22:32:24","TRT02EDTM":"2022-02-14 04:32:24","AP01SDTM":"2020-08-24 12:54:31","AP01EDTM":"2021-02-13 22:32:24","AP02SDTM":"2021-02-13 22:32:24","AP02EDTM":"2022-02-14 04:32:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":539,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":40,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":578,"ADTHAUT":"No","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1930,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.16368,"AVALU":"U/L","BASE2":14.16368,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-06 12:54:31","ADY":13,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-30","SUBJID":"id-30","SITEID":"CHN-6","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":12.22076,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 12:54:31","TRTEDTM":"2022-02-14 04:32:24","TRT01SDTM":"2020-08-24 12:54:31","TRT01EDTM":"2021-02-13 22:32:24","TRT02SDTM":"2021-02-13 22:32:24","TRT02EDTM":"2022-02-14 04:32:24","AP01SDTM":"2020-08-24 12:54:31","AP01EDTM":"2021-02-13 22:32:24","AP02SDTM":"2021-02-13 22:32:24","AP02EDTM":"2022-02-14 04:32:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":539,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":40,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":578,"ADTHAUT":"No","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3200,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.5899,"AVALU":"U/L","BASE2":14.16368,"BASE":8.5899,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-5.57378,"PCHG2":-39.3526,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-08 12:54:31","ADY":76,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-30","SUBJID":"id-30","SITEID":"CHN-6","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":12.22076,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 12:54:31","TRTEDTM":"2022-02-14 04:32:24","TRT01SDTM":"2020-08-24 12:54:31","TRT01EDTM":"2021-02-13 22:32:24","TRT02SDTM":"2021-02-13 22:32:24","TRT02EDTM":"2022-02-14 04:32:24","AP01SDTM":"2020-08-24 12:54:31","AP01EDTM":"2021-02-13 22:32:24","AP02SDTM":"2021-02-13 22:32:24","AP02EDTM":"2022-02-14 04:32:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":539,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":40,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":578,"ADTHAUT":"No","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6860,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.97903,"AVALU":"U/L","BASE2":14.16368,"BASE":8.5899,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.81535,"PCHG2":12.81693,"CHG":7.38912,"PCHG":86.02105,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-02 12:54:31","ADY":100,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-30","SUBJID":"id-30","SITEID":"CHN-6","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":12.22076,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 12:54:31","TRTEDTM":"2022-02-14 04:32:24","TRT01SDTM":"2020-08-24 12:54:31","TRT01EDTM":"2021-02-13 22:32:24","TRT02SDTM":"2021-02-13 22:32:24","TRT02EDTM":"2022-02-14 04:32:24","AP01SDTM":"2020-08-24 12:54:31","AP01EDTM":"2021-02-13 22:32:24","AP02SDTM":"2021-02-13 22:32:24","AP02EDTM":"2022-02-14 04:32:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":539,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":40,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":578,"ADTHAUT":"No","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6981,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.61274,"AVALU":"U/L","BASE2":14.16368,"BASE":8.5899,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.44907,"PCHG2":87.8943,"CHG":18.02284,"PCHG":209.81428,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-31 12:54:31","ADY":129,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-30","SUBJID":"id-30","SITEID":"CHN-6","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":12.22076,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 12:54:31","TRTEDTM":"2022-02-14 04:32:24","TRT01SDTM":"2020-08-24 12:54:31","TRT01EDTM":"2021-02-13 22:32:24","TRT02SDTM":"2021-02-13 22:32:24","TRT02EDTM":"2022-02-14 04:32:24","AP01SDTM":"2020-08-24 12:54:31","AP01EDTM":"2021-02-13 22:32:24","AP02SDTM":"2021-02-13 22:32:24","AP02EDTM":"2022-02-14 04:32:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":539,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":40,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":578,"ADTHAUT":"No","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5110,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.43458,"AVALU":"U/L","BASE2":14.16368,"BASE":8.5899,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.7291,"PCHG2":-26.32862,"CHG":1.84468,"PCHG":21.47493,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-28 12:54:31","ADY":369,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-30","SUBJID":"id-30","SITEID":"CHN-6","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":12.22076,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 12:54:31","TRTEDTM":"2022-02-14 04:32:24","TRT01SDTM":"2020-08-24 12:54:31","TRT01EDTM":"2021-02-13 22:32:24","TRT02SDTM":"2021-02-13 22:32:24","TRT02EDTM":"2022-02-14 04:32:24","AP01SDTM":"2020-08-24 12:54:31","AP01EDTM":"2021-02-13 22:32:24","AP02SDTM":"2021-02-13 22:32:24","AP02EDTM":"2022-02-14 04:32:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":539,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":40,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":578,"ADTHAUT":"No","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5637,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.58593,"AVALU":"U/L","BASE2":14.16368,"BASE":8.5899,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.57775,"PCHG2":-39.38063,"CHG":-0.00397,"PCHG":-0.04621,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-24 12:54:31","ADY":487,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-30","SUBJID":"id-30","SITEID":"CHN-6","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":12.22076,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 12:54:31","TRTEDTM":"2022-02-14 04:32:24","TRT01SDTM":"2020-08-24 12:54:31","TRT01EDTM":"2021-02-13 22:32:24","TRT02SDTM":"2021-02-13 22:32:24","TRT02EDTM":"2022-02-14 04:32:24","AP01SDTM":"2020-08-24 12:54:31","AP01EDTM":"2021-02-13 22:32:24","AP02SDTM":"2021-02-13 22:32:24","AP02EDTM":"2022-02-14 04:32:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":539,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":40,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":578,"ADTHAUT":"No","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3558,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.19201,"AVALU":"U/L","BASE2":14.16368,"BASE":8.5899,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.02833,"PCHG2":99.04437,"CHG":19.6021,"PCHG":228.19936,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-28 12:54:31","ADY":491,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-30","SUBJID":"id-30","SITEID":"CHN-6","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":12.22076,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 12:54:31","TRTEDTM":"2022-02-14 04:32:24","TRT01SDTM":"2020-08-24 12:54:31","TRT01EDTM":"2021-02-13 22:32:24","TRT02SDTM":"2021-02-13 22:32:24","TRT02EDTM":"2022-02-14 04:32:24","AP01SDTM":"2020-08-24 12:54:31","AP01EDTM":"2021-02-13 22:32:24","AP02SDTM":"2021-02-13 22:32:24","AP02EDTM":"2022-02-14 04:32:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":539,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":40,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":578,"ADTHAUT":"No","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6668,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.08681,"AVALU":"mg/L","BASE2":9.08681,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-09-06 12:54:31","ADY":13,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-30","SUBJID":"id-30","SITEID":"CHN-6","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":12.22076,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 12:54:31","TRTEDTM":"2022-02-14 04:32:24","TRT01SDTM":"2020-08-24 12:54:31","TRT01EDTM":"2021-02-13 22:32:24","TRT02SDTM":"2021-02-13 22:32:24","TRT02EDTM":"2022-02-14 04:32:24","AP01SDTM":"2020-08-24 12:54:31","AP01EDTM":"2021-02-13 22:32:24","AP02SDTM":"2021-02-13 22:32:24","AP02EDTM":"2022-02-14 04:32:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":539,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":40,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":578,"ADTHAUT":"No","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1030,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.2029,"AVALU":"mg/L","BASE2":9.08681,"BASE":11.2029,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.11609,"PCHG2":23.28745,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-11-08 12:54:31","ADY":76,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-30","SUBJID":"id-30","SITEID":"CHN-6","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":12.22076,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 12:54:31","TRTEDTM":"2022-02-14 04:32:24","TRT01SDTM":"2020-08-24 12:54:31","TRT01EDTM":"2021-02-13 22:32:24","TRT02SDTM":"2021-02-13 22:32:24","TRT02EDTM":"2022-02-14 04:32:24","AP01SDTM":"2020-08-24 12:54:31","AP01EDTM":"2021-02-13 22:32:24","AP02SDTM":"2021-02-13 22:32:24","AP02EDTM":"2022-02-14 04:32:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":539,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":40,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":578,"ADTHAUT":"No","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":945,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.2863,"AVALU":"mg/L","BASE2":9.08681,"BASE":11.2029,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.19949,"PCHG2":2.19539,"CHG":-1.9166,"PCHG":-17.10804,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-12-02 12:54:31","ADY":100,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-30","SUBJID":"id-30","SITEID":"CHN-6","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":12.22076,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 12:54:31","TRTEDTM":"2022-02-14 04:32:24","TRT01SDTM":"2020-08-24 12:54:31","TRT01EDTM":"2021-02-13 22:32:24","TRT02SDTM":"2021-02-13 22:32:24","TRT02EDTM":"2022-02-14 04:32:24","AP01SDTM":"2020-08-24 12:54:31","AP01EDTM":"2021-02-13 22:32:24","AP02SDTM":"2021-02-13 22:32:24","AP02EDTM":"2022-02-14 04:32:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":539,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":40,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":578,"ADTHAUT":"No","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4548,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.08751,"AVALU":"mg/L","BASE2":9.08681,"BASE":11.2029,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.0007,"PCHG2":11.01272,"CHG":-1.11538,"PCHG":-9.95619,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"3","BTOXGR":"1","ADTM":"2020-12-31 12:54:31","ADY":129,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-30","SUBJID":"id-30","SITEID":"CHN-6","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":12.22076,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 12:54:31","TRTEDTM":"2022-02-14 04:32:24","TRT01SDTM":"2020-08-24 12:54:31","TRT01EDTM":"2021-02-13 22:32:24","TRT02SDTM":"2021-02-13 22:32:24","TRT02EDTM":"2022-02-14 04:32:24","AP01SDTM":"2020-08-24 12:54:31","AP01EDTM":"2021-02-13 22:32:24","AP02SDTM":"2021-02-13 22:32:24","AP02EDTM":"2022-02-14 04:32:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":539,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":40,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":578,"ADTHAUT":"No","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6313,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.42828,"AVALU":"mg/L","BASE2":9.08681,"BASE":11.2029,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.34147,"PCHG2":3.75789,"CHG":-1.77461,"PCHG":-15.84067,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-08-28 12:54:31","ADY":369,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-30","SUBJID":"id-30","SITEID":"CHN-6","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":12.22076,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 12:54:31","TRTEDTM":"2022-02-14 04:32:24","TRT01SDTM":"2020-08-24 12:54:31","TRT01EDTM":"2021-02-13 22:32:24","TRT02SDTM":"2021-02-13 22:32:24","TRT02EDTM":"2022-02-14 04:32:24","AP01SDTM":"2020-08-24 12:54:31","AP01EDTM":"2021-02-13 22:32:24","AP02SDTM":"2021-02-13 22:32:24","AP02EDTM":"2022-02-14 04:32:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":539,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":40,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":578,"ADTHAUT":"No","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4598,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.90451,"AVALU":"mg/L","BASE2":9.08681,"BASE":11.2029,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.1823,"PCHG2":-13.01113,"CHG":-3.29838,"PCHG":-29.44224,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-2","BTOXGR":"1","ADTM":"2021-12-24 12:54:31","ADY":487,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-30","SUBJID":"id-30","SITEID":"CHN-6","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":12.22076,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 12:54:31","TRTEDTM":"2022-02-14 04:32:24","TRT01SDTM":"2020-08-24 12:54:31","TRT01EDTM":"2021-02-13 22:32:24","TRT02SDTM":"2021-02-13 22:32:24","TRT02EDTM":"2022-02-14 04:32:24","AP01SDTM":"2020-08-24 12:54:31","AP01EDTM":"2021-02-13 22:32:24","AP02SDTM":"2021-02-13 22:32:24","AP02EDTM":"2022-02-14 04:32:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":539,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":40,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":578,"ADTHAUT":"No","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2110,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.5937,"AVALU":"mg/L","BASE2":9.08681,"BASE":11.2029,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.49311,"PCHG2":-5.42661,"CHG":-2.60919,"PCHG":-23.29033,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-12-28 12:54:31","ADY":491,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-30","SUBJID":"id-30","SITEID":"CHN-6","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":12.22076,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 12:54:31","TRTEDTM":"2022-02-14 04:32:24","TRT01SDTM":"2020-08-24 12:54:31","TRT01EDTM":"2021-02-13 22:32:24","TRT02SDTM":"2021-02-13 22:32:24","TRT02EDTM":"2022-02-14 04:32:24","AP01SDTM":"2020-08-24 12:54:31","AP01EDTM":"2021-02-13 22:32:24","AP02SDTM":"2021-02-13 22:32:24","AP02EDTM":"2022-02-14 04:32:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":539,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":40,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":578,"ADTHAUT":"No","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":213,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88861,"AVALU":"g/L","BASE2":2.88861,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-06 12:54:31","ADY":13,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-30","SUBJID":"id-30","SITEID":"CHN-6","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":12.22076,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 12:54:31","TRTEDTM":"2022-02-14 04:32:24","TRT01SDTM":"2020-08-24 12:54:31","TRT01EDTM":"2021-02-13 22:32:24","TRT02SDTM":"2021-02-13 22:32:24","TRT02EDTM":"2022-02-14 04:32:24","AP01SDTM":"2020-08-24 12:54:31","AP01EDTM":"2021-02-13 22:32:24","AP02SDTM":"2021-02-13 22:32:24","AP02EDTM":"2022-02-14 04:32:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":539,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":40,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":578,"ADTHAUT":"No","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6911,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84178,"AVALU":"g/L","BASE2":2.88861,"BASE":2.84178,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.04683,"PCHG2":-1.62114,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-08 12:54:31","ADY":76,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-30","SUBJID":"id-30","SITEID":"CHN-6","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":12.22076,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 12:54:31","TRTEDTM":"2022-02-14 04:32:24","TRT01SDTM":"2020-08-24 12:54:31","TRT01EDTM":"2021-02-13 22:32:24","TRT02SDTM":"2021-02-13 22:32:24","TRT02EDTM":"2022-02-14 04:32:24","AP01SDTM":"2020-08-24 12:54:31","AP01EDTM":"2021-02-13 22:32:24","AP02SDTM":"2021-02-13 22:32:24","AP02EDTM":"2022-02-14 04:32:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":539,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":40,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":578,"ADTHAUT":"No","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7082,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85399,"AVALU":"g/L","BASE2":2.88861,"BASE":2.84178,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03462,"PCHG2":-1.19846,"CHG":0.01221,"PCHG":0.42965,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-02 12:54:31","ADY":100,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-30","SUBJID":"id-30","SITEID":"CHN-6","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":12.22076,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 12:54:31","TRTEDTM":"2022-02-14 04:32:24","TRT01SDTM":"2020-08-24 12:54:31","TRT01EDTM":"2021-02-13 22:32:24","TRT02SDTM":"2021-02-13 22:32:24","TRT02EDTM":"2022-02-14 04:32:24","AP01SDTM":"2020-08-24 12:54:31","AP01EDTM":"2021-02-13 22:32:24","AP02SDTM":"2021-02-13 22:32:24","AP02EDTM":"2022-02-14 04:32:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":539,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":40,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":578,"ADTHAUT":"No","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7214,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90047,"AVALU":"g/L","BASE2":2.88861,"BASE":2.84178,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01186,"PCHG2":0.4105,"CHG":0.05869,"PCHG":2.06512,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-31 12:54:31","ADY":129,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-30","SUBJID":"id-30","SITEID":"CHN-6","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":12.22076,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 12:54:31","TRTEDTM":"2022-02-14 04:32:24","TRT01SDTM":"2020-08-24 12:54:31","TRT01EDTM":"2021-02-13 22:32:24","TRT02SDTM":"2021-02-13 22:32:24","TRT02EDTM":"2022-02-14 04:32:24","AP01SDTM":"2020-08-24 12:54:31","AP01EDTM":"2021-02-13 22:32:24","AP02SDTM":"2021-02-13 22:32:24","AP02EDTM":"2022-02-14 04:32:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":539,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":40,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":578,"ADTHAUT":"No","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":902,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87189,"AVALU":"g/L","BASE2":2.88861,"BASE":2.84178,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01672,"PCHG2":-0.57893,"CHG":0.03011,"PCHG":1.05939,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-28 12:54:31","ADY":369,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-30","SUBJID":"id-30","SITEID":"CHN-6","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":12.22076,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 12:54:31","TRTEDTM":"2022-02-14 04:32:24","TRT01SDTM":"2020-08-24 12:54:31","TRT01EDTM":"2021-02-13 22:32:24","TRT02SDTM":"2021-02-13 22:32:24","TRT02EDTM":"2022-02-14 04:32:24","AP01SDTM":"2020-08-24 12:54:31","AP01EDTM":"2021-02-13 22:32:24","AP02SDTM":"2021-02-13 22:32:24","AP02EDTM":"2022-02-14 04:32:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":539,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":40,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":578,"ADTHAUT":"No","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1162,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87271,"AVALU":"g/L","BASE2":2.88861,"BASE":2.84178,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0159,"PCHG2":-0.55042,"CHG":0.03093,"PCHG":1.08836,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-24 12:54:31","ADY":487,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-30","SUBJID":"id-30","SITEID":"CHN-6","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":12.22076,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-24 12:54:31","TRTEDTM":"2022-02-14 04:32:24","TRT01SDTM":"2020-08-24 12:54:31","TRT01EDTM":"2021-02-13 22:32:24","TRT02SDTM":"2021-02-13 22:32:24","TRT02EDTM":"2022-02-14 04:32:24","AP01SDTM":"2020-08-24 12:54:31","AP01EDTM":"2021-02-13 22:32:24","AP02SDTM":"2021-02-13 22:32:24","AP02EDTM":"2022-02-14 04:32:24","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":539,"DCSREAS":"DEATH","DTHDT":"2022-03-26","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":40,"LDDTHGR1":">30","LSTALVDT":"2022-03-26","DTHADY":578,"ADTHAUT":"No","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3922,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86428,"AVALU":"g/L","BASE2":2.88861,"BASE":2.84178,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02433,"PCHG2":-0.84243,"CHG":0.02249,"PCHG":0.79155,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-28 12:54:31","ADY":491,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-385","SUBJID":"id-385","SITEID":"CHN-6","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.68372,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-21 17:46:54","TRT01SDTM":"2019-11-21 17:46:54","AP01SDTM":"2019-11-21 17:46:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3879,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.3647,"AVALU":"U/L","BASE2":13.3647,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-22 17:46:54","ADY":122,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-385","SUBJID":"id-385","SITEID":"CHN-6","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.68372,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-21 17:46:54","TRT01SDTM":"2019-11-21 17:46:54","AP01SDTM":"2019-11-21 17:46:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2808,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.47295,"AVALU":"U/L","BASE2":13.3647,"BASE":26.47295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":13.10826,"PCHG2":98.08123,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-24 17:46:54","ADY":124,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-385","SUBJID":"id-385","SITEID":"CHN-6","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.68372,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-21 17:46:54","TRT01SDTM":"2019-11-21 17:46:54","AP01SDTM":"2019-11-21 17:46:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2060,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.47962,"AVALU":"U/L","BASE2":13.3647,"BASE":26.47295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.11492,"PCHG2":83.1663,"CHG":-1.99333,"PCHG":-7.5297,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-10 17:46:54","ADY":324,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-385","SUBJID":"id-385","SITEID":"CHN-6","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.68372,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-21 17:46:54","TRT01SDTM":"2019-11-21 17:46:54","AP01SDTM":"2019-11-21 17:46:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6287,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.67251,"AVALU":"U/L","BASE2":13.3647,"BASE":26.47295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.69219,"PCHG2":-27.62644,"CHG":-16.80045,"PCHG":-63.46268,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-21 17:46:54","ADY":366,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-385","SUBJID":"id-385","SITEID":"CHN-6","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.68372,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-21 17:46:54","TRT01SDTM":"2019-11-21 17:46:54","AP01SDTM":"2019-11-21 17:46:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5568,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.54113,"AVALU":"U/L","BASE2":13.3647,"BASE":26.47295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.17643,"PCHG2":61.17933,"CHG":-4.93183,"PCHG":-18.62968,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-24 17:46:54","ADY":520,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-385","SUBJID":"id-385","SITEID":"CHN-6","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.68372,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-21 17:46:54","TRT01SDTM":"2019-11-21 17:46:54","AP01SDTM":"2019-11-21 17:46:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6343,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.58192,"AVALU":"U/L","BASE2":13.3647,"BASE":26.47295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.78278,"PCHG2":-20.82185,"CHG":-15.89104,"PCHG":-60.02744,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-15 17:46:54","ADY":572,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-385","SUBJID":"id-385","SITEID":"CHN-6","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.68372,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-21 17:46:54","TRT01SDTM":"2019-11-21 17:46:54","AP01SDTM":"2019-11-21 17:46:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7476,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":35.03479,"AVALU":"U/L","BASE2":13.3647,"BASE":26.47295,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":21.6701,"PCHG2":162.14433,"CHG":8.56184,"PCHG":32.34183,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-19 17:46:54","ADY":698,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-385","SUBJID":"id-385","SITEID":"CHN-6","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.68372,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-21 17:46:54","TRT01SDTM":"2019-11-21 17:46:54","AP01SDTM":"2019-11-21 17:46:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1229,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.78788,"AVALU":"mg/L","BASE2":6.78788,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-03-22 17:46:54","ADY":122,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-385","SUBJID":"id-385","SITEID":"CHN-6","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.68372,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-21 17:46:54","TRT01SDTM":"2019-11-21 17:46:54","AP01SDTM":"2019-11-21 17:46:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3456,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.40711,"AVALU":"mg/L","BASE2":6.78788,"BASE":8.40711,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.61923,"PCHG2":23.85477,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-24 17:46:54","ADY":124,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-385","SUBJID":"id-385","SITEID":"CHN-6","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.68372,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-21 17:46:54","TRT01SDTM":"2019-11-21 17:46:54","AP01SDTM":"2019-11-21 17:46:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":28,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.06041,"AVALU":"mg/L","BASE2":6.78788,"BASE":8.40711,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.27253,"PCHG2":62.9435,"CHG":2.6533,"PCHG":31.56014,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-10-10 17:46:54","ADY":324,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-385","SUBJID":"id-385","SITEID":"CHN-6","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.68372,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-21 17:46:54","TRT01SDTM":"2019-11-21 17:46:54","AP01SDTM":"2019-11-21 17:46:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":104,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.75641,"AVALU":"mg/L","BASE2":6.78788,"BASE":8.40711,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.96853,"PCHG2":29.00071,"CHG":0.3493,"PCHG":4.15482,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-21 17:46:54","ADY":366,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-385","SUBJID":"id-385","SITEID":"CHN-6","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.68372,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-21 17:46:54","TRT01SDTM":"2019-11-21 17:46:54","AP01SDTM":"2019-11-21 17:46:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4765,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.37271,"AVALU":"mg/L","BASE2":6.78788,"BASE":8.40711,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.58483,"PCHG2":38.08006,"CHG":0.9656,"PCHG":11.48546,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-24 17:46:54","ADY":520,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-385","SUBJID":"id-385","SITEID":"CHN-6","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.68372,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-21 17:46:54","TRT01SDTM":"2019-11-21 17:46:54","AP01SDTM":"2019-11-21 17:46:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3573,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.82834,"AVALU":"mg/L","BASE2":6.78788,"BASE":8.40711,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.04046,"PCHG2":44.79254,"CHG":1.42123,"PCHG":16.9051,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-15 17:46:54","ADY":572,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-385","SUBJID":"id-385","SITEID":"CHN-6","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.68372,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-21 17:46:54","TRT01SDTM":"2019-11-21 17:46:54","AP01SDTM":"2019-11-21 17:46:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7325,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.06016,"AVALU":"mg/L","BASE2":6.78788,"BASE":8.40711,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.27228,"PCHG2":18.74334,"CHG":-0.34696,"PCHG":-4.12695,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-19 17:46:54","ADY":698,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-385","SUBJID":"id-385","SITEID":"CHN-6","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.68372,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-21 17:46:54","TRT01SDTM":"2019-11-21 17:46:54","AP01SDTM":"2019-11-21 17:46:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4546,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94709,"AVALU":"g/L","BASE2":2.94709,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-22 17:46:54","ADY":122,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-385","SUBJID":"id-385","SITEID":"CHN-6","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.68372,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-21 17:46:54","TRT01SDTM":"2019-11-21 17:46:54","AP01SDTM":"2019-11-21 17:46:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3978,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98818,"AVALU":"g/L","BASE2":2.94709,"BASE":2.98818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.0411,"PCHG2":1.39453,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-24 17:46:54","ADY":124,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-385","SUBJID":"id-385","SITEID":"CHN-6","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.68372,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-21 17:46:54","TRT01SDTM":"2019-11-21 17:46:54","AP01SDTM":"2019-11-21 17:46:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2415,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.08003,"AVALU":"g/L","BASE2":2.94709,"BASE":2.98818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13295,"PCHG2":4.51111,"CHG":0.09185,"PCHG":3.07371,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-10-10 17:46:54","ADY":324,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-385","SUBJID":"id-385","SITEID":"CHN-6","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.68372,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-21 17:46:54","TRT01SDTM":"2019-11-21 17:46:54","AP01SDTM":"2019-11-21 17:46:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1439,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81573,"AVALU":"g/L","BASE2":2.94709,"BASE":2.98818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13136,"PCHG2":-4.45722,"CHG":-0.17246,"PCHG":-5.77128,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-21 17:46:54","ADY":366,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-385","SUBJID":"id-385","SITEID":"CHN-6","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.68372,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-21 17:46:54","TRT01SDTM":"2019-11-21 17:46:54","AP01SDTM":"2019-11-21 17:46:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2943,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92707,"AVALU":"g/L","BASE2":2.94709,"BASE":2.98818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02002,"PCHG2":-0.67921,"CHG":-0.06111,"PCHG":-2.04522,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-24 17:46:54","ADY":520,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-385","SUBJID":"id-385","SITEID":"CHN-6","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.68372,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-21 17:46:54","TRT01SDTM":"2019-11-21 17:46:54","AP01SDTM":"2019-11-21 17:46:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8241,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91335,"AVALU":"g/L","BASE2":2.94709,"BASE":2.98818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03373,"PCHG2":-1.14467,"CHG":-0.07483,"PCHG":-2.50429,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-15 17:46:54","ADY":572,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-385","SUBJID":"id-385","SITEID":"CHN-6","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.68372,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-21 17:46:54","TRT01SDTM":"2019-11-21 17:46:54","AP01SDTM":"2019-11-21 17:46:54","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1978,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86838,"AVALU":"g/L","BASE2":2.94709,"BASE":2.98818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07871,"PCHG2":-2.67072,"CHG":-0.11981,"PCHG":-4.00935,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-19 17:46:54","ADY":698,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-89","SUBJID":"id-89","SITEID":"CHN-6","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.35335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-23","TRTSDTM":"2021-01-23 18:55:06","TRTEDTM":"2024-01-24 12:55:06","TRT01SDTM":"2021-01-23 18:55:06","TRT01EDTM":"2023-01-24 06:55:06","TRT02SDTM":"2023-01-24 06:55:06","TRT02EDTM":"2024-01-24 12:55:06","AP01SDTM":"2021-01-23 18:55:06","AP01EDTM":"2023-01-24 06:55:06","AP02SDTM":"2023-01-24 06:55:06","AP02EDTM":"2024-01-24 12:55:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-24","EOSDY":1096,"LSTALVDT":"2024-02-16","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1319,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.15637,"AVALU":"U/L","BASE2":24.15637,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-22 18:55:06","ADY":119,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-89","SUBJID":"id-89","SITEID":"CHN-6","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.35335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-23","TRTSDTM":"2021-01-23 18:55:06","TRTEDTM":"2024-01-24 12:55:06","TRT01SDTM":"2021-01-23 18:55:06","TRT01EDTM":"2023-01-24 06:55:06","TRT02SDTM":"2023-01-24 06:55:06","TRT02EDTM":"2024-01-24 12:55:06","AP01SDTM":"2021-01-23 18:55:06","AP01EDTM":"2023-01-24 06:55:06","AP02SDTM":"2023-01-24 06:55:06","AP02EDTM":"2024-01-24 12:55:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-24","EOSDY":1096,"LSTALVDT":"2024-02-16","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4349,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.44029,"AVALU":"U/L","BASE2":24.15637,"BASE":9.44029,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-14.71608,"PCHG2":-60.92009,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-04 18:55:06","ADY":193,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-89","SUBJID":"id-89","SITEID":"CHN-6","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.35335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-23","TRTSDTM":"2021-01-23 18:55:06","TRTEDTM":"2024-01-24 12:55:06","TRT01SDTM":"2021-01-23 18:55:06","TRT01EDTM":"2023-01-24 06:55:06","TRT02SDTM":"2023-01-24 06:55:06","TRT02EDTM":"2024-01-24 12:55:06","AP01SDTM":"2021-01-23 18:55:06","AP01EDTM":"2023-01-24 06:55:06","AP02SDTM":"2023-01-24 06:55:06","AP02EDTM":"2024-01-24 12:55:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-24","EOSDY":1096,"LSTALVDT":"2024-02-16","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":467,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.95915,"AVALU":"U/L","BASE2":24.15637,"BASE":9.44029,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.19722,"PCHG2":-38.07369,"CHG":5.51886,"PCHG":58.46071,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-05 18:55:06","ADY":467,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-89","SUBJID":"id-89","SITEID":"CHN-6","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.35335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-23","TRTSDTM":"2021-01-23 18:55:06","TRTEDTM":"2024-01-24 12:55:06","TRT01SDTM":"2021-01-23 18:55:06","TRT01EDTM":"2023-01-24 06:55:06","TRT02SDTM":"2023-01-24 06:55:06","TRT02EDTM":"2024-01-24 12:55:06","AP01SDTM":"2021-01-23 18:55:06","AP01EDTM":"2023-01-24 06:55:06","AP02SDTM":"2023-01-24 06:55:06","AP02EDTM":"2024-01-24 12:55:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-24","EOSDY":1096,"LSTALVDT":"2024-02-16","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6437,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.72038,"AVALU":"U/L","BASE2":24.15637,"BASE":9.44029,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.43599,"PCHG2":-30.78274,"CHG":7.28009,"PCHG":77.11722,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-20 18:55:06","ADY":574,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-89","SUBJID":"id-89","SITEID":"CHN-6","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.35335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-23","TRTSDTM":"2021-01-23 18:55:06","TRTEDTM":"2024-01-24 12:55:06","TRT01SDTM":"2021-01-23 18:55:06","TRT01EDTM":"2023-01-24 06:55:06","TRT02SDTM":"2023-01-24 06:55:06","TRT02EDTM":"2024-01-24 12:55:06","AP01SDTM":"2021-01-23 18:55:06","AP01EDTM":"2023-01-24 06:55:06","AP02SDTM":"2023-01-24 06:55:06","AP02EDTM":"2024-01-24 12:55:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-24","EOSDY":1096,"LSTALVDT":"2024-02-16","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3267,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.95806,"AVALU":"U/L","BASE2":24.15637,"BASE":9.44029,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-15.1983,"PCHG2":-62.91634,"CHG":-0.48222,"PCHG":-5.10814,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-28 18:55:06","ADY":825,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-89","SUBJID":"id-89","SITEID":"CHN-6","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.35335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-23","TRTSDTM":"2021-01-23 18:55:06","TRTEDTM":"2024-01-24 12:55:06","TRT01SDTM":"2021-01-23 18:55:06","TRT01EDTM":"2023-01-24 06:55:06","TRT02SDTM":"2023-01-24 06:55:06","TRT02EDTM":"2024-01-24 12:55:06","AP01SDTM":"2021-01-23 18:55:06","AP01EDTM":"2023-01-24 06:55:06","AP02SDTM":"2023-01-24 06:55:06","AP02EDTM":"2024-01-24 12:55:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-24","EOSDY":1096,"LSTALVDT":"2024-02-16","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1470,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":42.72741,"AVALU":"U/L","BASE2":24.15637,"BASE":9.44029,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.57104,"PCHG2":76.87844,"CHG":33.28712,"PCHG":352.60704,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-15 18:55:06","ADY":842,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-89","SUBJID":"id-89","SITEID":"CHN-6","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.35335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-23","TRTSDTM":"2021-01-23 18:55:06","TRTEDTM":"2024-01-24 12:55:06","TRT01SDTM":"2021-01-23 18:55:06","TRT01EDTM":"2023-01-24 06:55:06","TRT02SDTM":"2023-01-24 06:55:06","TRT02EDTM":"2024-01-24 12:55:06","AP01SDTM":"2021-01-23 18:55:06","AP01EDTM":"2023-01-24 06:55:06","AP02SDTM":"2023-01-24 06:55:06","AP02EDTM":"2024-01-24 12:55:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-24","EOSDY":1096,"LSTALVDT":"2024-02-16","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8213,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.92361,"AVALU":"U/L","BASE2":24.15637,"BASE":9.44029,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.23276,"PCHG2":-50.6399,"CHG":2.48332,"PCHG":26.30555,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-06 18:55:06","ADY":894,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-89","SUBJID":"id-89","SITEID":"CHN-6","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.35335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-23","TRTSDTM":"2021-01-23 18:55:06","TRTEDTM":"2024-01-24 12:55:06","TRT01SDTM":"2021-01-23 18:55:06","TRT01EDTM":"2023-01-24 06:55:06","TRT02SDTM":"2023-01-24 06:55:06","TRT02EDTM":"2024-01-24 12:55:06","AP01SDTM":"2021-01-23 18:55:06","AP01EDTM":"2023-01-24 06:55:06","AP02SDTM":"2023-01-24 06:55:06","AP02EDTM":"2024-01-24 12:55:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-24","EOSDY":1096,"LSTALVDT":"2024-02-16","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8267,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.69671,"AVALU":"mg/L","BASE2":8.69671,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-05-22 18:55:06","ADY":119,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-89","SUBJID":"id-89","SITEID":"CHN-6","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.35335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-23","TRTSDTM":"2021-01-23 18:55:06","TRTEDTM":"2024-01-24 12:55:06","TRT01SDTM":"2021-01-23 18:55:06","TRT01EDTM":"2023-01-24 06:55:06","TRT02SDTM":"2023-01-24 06:55:06","TRT02EDTM":"2024-01-24 12:55:06","AP01SDTM":"2021-01-23 18:55:06","AP01EDTM":"2023-01-24 06:55:06","AP02SDTM":"2023-01-24 06:55:06","AP02EDTM":"2024-01-24 12:55:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-24","EOSDY":1096,"LSTALVDT":"2024-02-16","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5880,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.55033,"AVALU":"mg/L","BASE2":8.69671,"BASE":7.55033,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.14638,"PCHG2":-13.18175,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2021-08-04 18:55:06","ADY":193,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-89","SUBJID":"id-89","SITEID":"CHN-6","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.35335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-23","TRTSDTM":"2021-01-23 18:55:06","TRTEDTM":"2024-01-24 12:55:06","TRT01SDTM":"2021-01-23 18:55:06","TRT01EDTM":"2023-01-24 06:55:06","TRT02SDTM":"2023-01-24 06:55:06","TRT02EDTM":"2024-01-24 12:55:06","AP01SDTM":"2021-01-23 18:55:06","AP01EDTM":"2023-01-24 06:55:06","AP02SDTM":"2023-01-24 06:55:06","AP02EDTM":"2024-01-24 12:55:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-24","EOSDY":1096,"LSTALVDT":"2024-02-16","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3935,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.34166,"AVALU":"mg/L","BASE2":8.69671,"BASE":7.55033,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.35504,"PCHG2":-4.08251,"CHG":0.79133,"PCHG":10.48078,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-05-05 18:55:06","ADY":467,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-89","SUBJID":"id-89","SITEID":"CHN-6","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.35335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-23","TRTSDTM":"2021-01-23 18:55:06","TRTEDTM":"2024-01-24 12:55:06","TRT01SDTM":"2021-01-23 18:55:06","TRT01EDTM":"2023-01-24 06:55:06","TRT02SDTM":"2023-01-24 06:55:06","TRT02EDTM":"2024-01-24 12:55:06","AP01SDTM":"2021-01-23 18:55:06","AP01EDTM":"2023-01-24 06:55:06","AP02SDTM":"2023-01-24 06:55:06","AP02EDTM":"2024-01-24 12:55:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-24","EOSDY":1096,"LSTALVDT":"2024-02-16","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4803,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.53665,"AVALU":"mg/L","BASE2":8.69671,"BASE":7.55033,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.83995,"PCHG2":9.65821,"CHG":1.98632,"PCHG":26.30778,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-08-20 18:55:06","ADY":574,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-89","SUBJID":"id-89","SITEID":"CHN-6","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.35335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-23","TRTSDTM":"2021-01-23 18:55:06","TRTEDTM":"2024-01-24 12:55:06","TRT01SDTM":"2021-01-23 18:55:06","TRT01EDTM":"2023-01-24 06:55:06","TRT02SDTM":"2023-01-24 06:55:06","TRT02EDTM":"2024-01-24 12:55:06","AP01SDTM":"2021-01-23 18:55:06","AP01EDTM":"2023-01-24 06:55:06","AP02SDTM":"2023-01-24 06:55:06","AP02EDTM":"2024-01-24 12:55:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-24","EOSDY":1096,"LSTALVDT":"2024-02-16","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":767,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.09349,"AVALU":"mg/L","BASE2":8.69671,"BASE":7.55033,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.60322,"PCHG2":-6.93616,"CHG":0.54316,"PCHG":7.19387,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2023-04-28 18:55:06","ADY":825,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-89","SUBJID":"id-89","SITEID":"CHN-6","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.35335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-23","TRTSDTM":"2021-01-23 18:55:06","TRTEDTM":"2024-01-24 12:55:06","TRT01SDTM":"2021-01-23 18:55:06","TRT01EDTM":"2023-01-24 06:55:06","TRT02SDTM":"2023-01-24 06:55:06","TRT02EDTM":"2024-01-24 12:55:06","AP01SDTM":"2021-01-23 18:55:06","AP01EDTM":"2023-01-24 06:55:06","AP02SDTM":"2023-01-24 06:55:06","AP02EDTM":"2024-01-24 12:55:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-24","EOSDY":1096,"LSTALVDT":"2024-02-16","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7451,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.88788,"AVALU":"mg/L","BASE2":8.69671,"BASE":7.55033,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.19117,"PCHG2":2.1982,"CHG":1.33755,"PCHG":17.71511,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2023-05-15 18:55:06","ADY":842,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-89","SUBJID":"id-89","SITEID":"CHN-6","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.35335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-23","TRTSDTM":"2021-01-23 18:55:06","TRTEDTM":"2024-01-24 12:55:06","TRT01SDTM":"2021-01-23 18:55:06","TRT01EDTM":"2023-01-24 06:55:06","TRT02SDTM":"2023-01-24 06:55:06","TRT02EDTM":"2024-01-24 12:55:06","AP01SDTM":"2021-01-23 18:55:06","AP01EDTM":"2023-01-24 06:55:06","AP02SDTM":"2023-01-24 06:55:06","AP02EDTM":"2024-01-24 12:55:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-24","EOSDY":1096,"LSTALVDT":"2024-02-16","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6676,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.75704,"AVALU":"mg/L","BASE2":8.69671,"BASE":7.55033,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.06033,"PCHG2":12.19232,"CHG":2.20671,"PCHG":29.22665,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2023-07-06 18:55:06","ADY":894,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-89","SUBJID":"id-89","SITEID":"CHN-6","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.35335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-23","TRTSDTM":"2021-01-23 18:55:06","TRTEDTM":"2024-01-24 12:55:06","TRT01SDTM":"2021-01-23 18:55:06","TRT01EDTM":"2023-01-24 06:55:06","TRT02SDTM":"2023-01-24 06:55:06","TRT02EDTM":"2024-01-24 12:55:06","AP01SDTM":"2021-01-23 18:55:06","AP01EDTM":"2023-01-24 06:55:06","AP02SDTM":"2023-01-24 06:55:06","AP02EDTM":"2024-01-24 12:55:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-24","EOSDY":1096,"LSTALVDT":"2024-02-16","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6639,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79188,"AVALU":"g/L","BASE2":2.79188,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-22 18:55:06","ADY":119,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-89","SUBJID":"id-89","SITEID":"CHN-6","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.35335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-23","TRTSDTM":"2021-01-23 18:55:06","TRTEDTM":"2024-01-24 12:55:06","TRT01SDTM":"2021-01-23 18:55:06","TRT01EDTM":"2023-01-24 06:55:06","TRT02SDTM":"2023-01-24 06:55:06","TRT02EDTM":"2024-01-24 12:55:06","AP01SDTM":"2021-01-23 18:55:06","AP01EDTM":"2023-01-24 06:55:06","AP02SDTM":"2023-01-24 06:55:06","AP02EDTM":"2024-01-24 12:55:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-24","EOSDY":1096,"LSTALVDT":"2024-02-16","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":341,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.72398,"AVALU":"g/L","BASE2":2.79188,"BASE":2.72398,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.0679,"PCHG2":-2.43207,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-04 18:55:06","ADY":193,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-89","SUBJID":"id-89","SITEID":"CHN-6","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.35335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-23","TRTSDTM":"2021-01-23 18:55:06","TRTEDTM":"2024-01-24 12:55:06","TRT01SDTM":"2021-01-23 18:55:06","TRT01EDTM":"2023-01-24 06:55:06","TRT02SDTM":"2023-01-24 06:55:06","TRT02EDTM":"2024-01-24 12:55:06","AP01SDTM":"2021-01-23 18:55:06","AP01EDTM":"2023-01-24 06:55:06","AP02SDTM":"2023-01-24 06:55:06","AP02EDTM":"2024-01-24 12:55:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-24","EOSDY":1096,"LSTALVDT":"2024-02-16","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5571,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80307,"AVALU":"g/L","BASE2":2.79188,"BASE":2.72398,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01119,"PCHG2":0.40079,"CHG":0.07909,"PCHG":2.90347,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-05 18:55:06","ADY":467,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-89","SUBJID":"id-89","SITEID":"CHN-6","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.35335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-23","TRTSDTM":"2021-01-23 18:55:06","TRTEDTM":"2024-01-24 12:55:06","TRT01SDTM":"2021-01-23 18:55:06","TRT01EDTM":"2023-01-24 06:55:06","TRT02SDTM":"2023-01-24 06:55:06","TRT02EDTM":"2024-01-24 12:55:06","AP01SDTM":"2021-01-23 18:55:06","AP01EDTM":"2023-01-24 06:55:06","AP02SDTM":"2023-01-24 06:55:06","AP02EDTM":"2024-01-24 12:55:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-24","EOSDY":1096,"LSTALVDT":"2024-02-16","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3177,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83526,"AVALU":"g/L","BASE2":2.79188,"BASE":2.72398,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04338,"PCHG2":1.55379,"CHG":0.11128,"PCHG":4.08522,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-20 18:55:06","ADY":574,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-89","SUBJID":"id-89","SITEID":"CHN-6","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.35335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-23","TRTSDTM":"2021-01-23 18:55:06","TRTEDTM":"2024-01-24 12:55:06","TRT01SDTM":"2021-01-23 18:55:06","TRT01EDTM":"2023-01-24 06:55:06","TRT02SDTM":"2023-01-24 06:55:06","TRT02EDTM":"2024-01-24 12:55:06","AP01SDTM":"2021-01-23 18:55:06","AP01EDTM":"2023-01-24 06:55:06","AP02SDTM":"2023-01-24 06:55:06","AP02EDTM":"2024-01-24 12:55:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-24","EOSDY":1096,"LSTALVDT":"2024-02-16","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5329,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05013,"AVALU":"g/L","BASE2":2.79188,"BASE":2.72398,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.25826,"PCHG2":9.25025,"CHG":0.32616,"PCHG":11.97353,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2023-04-28 18:55:06","ADY":825,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-89","SUBJID":"id-89","SITEID":"CHN-6","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.35335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-23","TRTSDTM":"2021-01-23 18:55:06","TRTEDTM":"2024-01-24 12:55:06","TRT01SDTM":"2021-01-23 18:55:06","TRT01EDTM":"2023-01-24 06:55:06","TRT02SDTM":"2023-01-24 06:55:06","TRT02EDTM":"2024-01-24 12:55:06","AP01SDTM":"2021-01-23 18:55:06","AP01EDTM":"2023-01-24 06:55:06","AP02SDTM":"2023-01-24 06:55:06","AP02EDTM":"2024-01-24 12:55:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-24","EOSDY":1096,"LSTALVDT":"2024-02-16","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2615,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87521,"AVALU":"g/L","BASE2":2.79188,"BASE":2.72398,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08333,"PCHG2":2.98474,"CHG":0.15123,"PCHG":5.55184,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-15 18:55:06","ADY":842,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-6-id-89","SUBJID":"id-89","SITEID":"CHN-6","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-6","INVNAM":"Dr. CHN-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":10.35335,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-23","TRTSDTM":"2021-01-23 18:55:06","TRTEDTM":"2024-01-24 12:55:06","TRT01SDTM":"2021-01-23 18:55:06","TRT01EDTM":"2023-01-24 06:55:06","TRT02SDTM":"2023-01-24 06:55:06","TRT02EDTM":"2024-01-24 12:55:06","AP01SDTM":"2021-01-23 18:55:06","AP01EDTM":"2023-01-24 06:55:06","AP02SDTM":"2023-01-24 06:55:06","AP02EDTM":"2024-01-24 12:55:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-24","EOSDY":1096,"LSTALVDT":"2024-02-16","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8021,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.61746,"AVALU":"g/L","BASE2":2.79188,"BASE":2.72398,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17442,"PCHG2":-6.24732,"CHG":-0.10652,"PCHG":-3.91035,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-06 18:55:06","ADY":894,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-126","SUBJID":"id-126","SITEID":"CHN-7","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.77455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-02","TRTSDTM":"2019-05-02 14:23:21","TRTEDTM":"2022-02-20 00:30:20","TRT01SDTM":"2019-05-02 14:23:21","TRT01EDTM":"2021-02-19 18:30:20","TRT02SDTM":"2021-02-19 18:30:20","TRT02EDTM":"2022-02-20 00:30:20","AP01SDTM":"2019-05-02 14:23:21","AP01EDTM":"2021-02-19 18:30:20","AP02SDTM":"2021-02-19 18:30:20","AP02EDTM":"2022-02-20 00:30:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":42,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":1066,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7828,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.2294,"AVALU":"U/L","BASE2":4.2294,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2019-08-31 14:23:21","ADY":121,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-126","SUBJID":"id-126","SITEID":"CHN-7","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.77455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-02","TRTSDTM":"2019-05-02 14:23:21","TRTEDTM":"2022-02-20 00:30:20","TRT01SDTM":"2019-05-02 14:23:21","TRT01EDTM":"2021-02-19 18:30:20","TRT02SDTM":"2021-02-19 18:30:20","TRT02EDTM":"2022-02-20 00:30:20","AP01SDTM":"2019-05-02 14:23:21","AP01EDTM":"2021-02-19 18:30:20","AP02SDTM":"2021-02-19 18:30:20","AP02EDTM":"2022-02-20 00:30:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":42,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":1066,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6610,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.17277,"AVALU":"U/L","BASE2":4.2294,"BASE":7.17277,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.94337,"PCHG2":69.59295,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-02 14:23:21","ADY":336,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-126","SUBJID":"id-126","SITEID":"CHN-7","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.77455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-02","TRTSDTM":"2019-05-02 14:23:21","TRTEDTM":"2022-02-20 00:30:20","TRT01SDTM":"2019-05-02 14:23:21","TRT01EDTM":"2021-02-19 18:30:20","TRT02SDTM":"2021-02-19 18:30:20","TRT02EDTM":"2022-02-20 00:30:20","AP01SDTM":"2019-05-02 14:23:21","AP01EDTM":"2021-02-19 18:30:20","AP02SDTM":"2021-02-19 18:30:20","AP02EDTM":"2022-02-20 00:30:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":42,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":1066,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6323,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.46559,"AVALU":"U/L","BASE2":4.2294,"BASE":7.17277,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.23619,"PCHG2":383.88834,"CHG":13.29282,"PCHG":185.32337,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-15 14:23:21","ADY":379,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-126","SUBJID":"id-126","SITEID":"CHN-7","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.77455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-02","TRTSDTM":"2019-05-02 14:23:21","TRTEDTM":"2022-02-20 00:30:20","TRT01SDTM":"2019-05-02 14:23:21","TRT01EDTM":"2021-02-19 18:30:20","TRT02SDTM":"2021-02-19 18:30:20","TRT02EDTM":"2022-02-20 00:30:20","AP01SDTM":"2019-05-02 14:23:21","AP01EDTM":"2021-02-19 18:30:20","AP02SDTM":"2021-02-19 18:30:20","AP02EDTM":"2022-02-20 00:30:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":42,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":1066,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8353,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.90137,"AVALU":"U/L","BASE2":4.2294,"BASE":7.17277,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":17.67197,"PCHG2":417.83579,"CHG":14.7286,"PCHG":205.3404,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-27 14:23:21","ADY":514,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-126","SUBJID":"id-126","SITEID":"CHN-7","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.77455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-02","TRTSDTM":"2019-05-02 14:23:21","TRTEDTM":"2022-02-20 00:30:20","TRT01SDTM":"2019-05-02 14:23:21","TRT01EDTM":"2021-02-19 18:30:20","TRT02SDTM":"2021-02-19 18:30:20","TRT02EDTM":"2022-02-20 00:30:20","AP01SDTM":"2019-05-02 14:23:21","AP01EDTM":"2021-02-19 18:30:20","AP02SDTM":"2021-02-19 18:30:20","AP02EDTM":"2022-02-20 00:30:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":42,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":1066,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1569,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.85154,"AVALU":"U/L","BASE2":4.2294,"BASE":7.17277,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":17.62214,"PCHG2":416.65763,"CHG":14.67877,"PCHG":204.6457,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-01 14:23:21","ADY":761,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-126","SUBJID":"id-126","SITEID":"CHN-7","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.77455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-02","TRTSDTM":"2019-05-02 14:23:21","TRTEDTM":"2022-02-20 00:30:20","TRT01SDTM":"2019-05-02 14:23:21","TRT01EDTM":"2021-02-19 18:30:20","TRT02SDTM":"2021-02-19 18:30:20","TRT02EDTM":"2022-02-20 00:30:20","AP01SDTM":"2019-05-02 14:23:21","AP01EDTM":"2021-02-19 18:30:20","AP02SDTM":"2021-02-19 18:30:20","AP02EDTM":"2022-02-20 00:30:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":42,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":1066,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7835,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.06867,"AVALU":"U/L","BASE2":4.2294,"BASE":7.17277,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16073,"PCHG2":-3.80034,"CHG":-3.1041,"PCHG":-43.27615,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-09-29 14:23:21","ADY":881,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-126","SUBJID":"id-126","SITEID":"CHN-7","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.77455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-02","TRTSDTM":"2019-05-02 14:23:21","TRTEDTM":"2022-02-20 00:30:20","TRT01SDTM":"2019-05-02 14:23:21","TRT01EDTM":"2021-02-19 18:30:20","TRT02SDTM":"2021-02-19 18:30:20","TRT02EDTM":"2022-02-20 00:30:20","AP01SDTM":"2019-05-02 14:23:21","AP01EDTM":"2021-02-19 18:30:20","AP02SDTM":"2021-02-19 18:30:20","AP02EDTM":"2022-02-20 00:30:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":42,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":1066,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6925,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.1227,"AVALU":"U/L","BASE2":4.2294,"BASE":7.17277,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.89329,"PCHG2":375.78092,"CHG":12.94993,"PCHG":180.54286,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-10 14:23:21","ADY":923,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-126","SUBJID":"id-126","SITEID":"CHN-7","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.77455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-02","TRTSDTM":"2019-05-02 14:23:21","TRTEDTM":"2022-02-20 00:30:20","TRT01SDTM":"2019-05-02 14:23:21","TRT01EDTM":"2021-02-19 18:30:20","TRT02SDTM":"2021-02-19 18:30:20","TRT02EDTM":"2022-02-20 00:30:20","AP01SDTM":"2019-05-02 14:23:21","AP01EDTM":"2021-02-19 18:30:20","AP02SDTM":"2021-02-19 18:30:20","AP02EDTM":"2022-02-20 00:30:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":42,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":1066,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7468,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.85459,"AVALU":"mg/L","BASE2":8.85459,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"4","ADTM":"2019-08-31 14:23:21","ADY":121,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-126","SUBJID":"id-126","SITEID":"CHN-7","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.77455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-02","TRTSDTM":"2019-05-02 14:23:21","TRTEDTM":"2022-02-20 00:30:20","TRT01SDTM":"2019-05-02 14:23:21","TRT01EDTM":"2021-02-19 18:30:20","TRT02SDTM":"2021-02-19 18:30:20","TRT02EDTM":"2022-02-20 00:30:20","AP01SDTM":"2019-05-02 14:23:21","AP01EDTM":"2021-02-19 18:30:20","AP02SDTM":"2021-02-19 18:30:20","AP02EDTM":"2022-02-20 00:30:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":42,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":1066,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1856,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.59958,"AVALU":"mg/L","BASE2":8.85459,"BASE":10.59958,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.745,"PCHG2":19.70725,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"4","BTOXGR":"4","ADTM":"2020-04-02 14:23:21","ADY":336,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-126","SUBJID":"id-126","SITEID":"CHN-7","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.77455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-02","TRTSDTM":"2019-05-02 14:23:21","TRTEDTM":"2022-02-20 00:30:20","TRT01SDTM":"2019-05-02 14:23:21","TRT01EDTM":"2021-02-19 18:30:20","TRT02SDTM":"2021-02-19 18:30:20","TRT02EDTM":"2022-02-20 00:30:20","AP01SDTM":"2019-05-02 14:23:21","AP01EDTM":"2021-02-19 18:30:20","AP02SDTM":"2021-02-19 18:30:20","AP02EDTM":"2022-02-20 00:30:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":42,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":1066,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8214,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.46342,"AVALU":"mg/L","BASE2":8.85459,"BASE":10.59958,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.39117,"PCHG2":-15.71132,"CHG":-3.13617,"PCHG":-29.58766,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-3","BTOXGR":"4","ADTM":"2020-05-15 14:23:21","ADY":379,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-126","SUBJID":"id-126","SITEID":"CHN-7","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.77455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-02","TRTSDTM":"2019-05-02 14:23:21","TRTEDTM":"2022-02-20 00:30:20","TRT01SDTM":"2019-05-02 14:23:21","TRT01EDTM":"2021-02-19 18:30:20","TRT02SDTM":"2021-02-19 18:30:20","TRT02EDTM":"2022-02-20 00:30:20","AP01SDTM":"2019-05-02 14:23:21","AP01EDTM":"2021-02-19 18:30:20","AP02SDTM":"2021-02-19 18:30:20","AP02EDTM":"2022-02-20 00:30:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":42,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":1066,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4966,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.2513,"AVALU":"mg/L","BASE2":8.85459,"BASE":10.59958,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.60329,"PCHG2":-6.8133,"CHG":-2.34828,"PCHG":-22.1545,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2020-09-27 14:23:21","ADY":514,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-126","SUBJID":"id-126","SITEID":"CHN-7","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.77455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-02","TRTSDTM":"2019-05-02 14:23:21","TRTEDTM":"2022-02-20 00:30:20","TRT01SDTM":"2019-05-02 14:23:21","TRT01EDTM":"2021-02-19 18:30:20","TRT02SDTM":"2021-02-19 18:30:20","TRT02EDTM":"2022-02-20 00:30:20","AP01SDTM":"2019-05-02 14:23:21","AP01EDTM":"2021-02-19 18:30:20","AP02SDTM":"2021-02-19 18:30:20","AP02EDTM":"2022-02-20 00:30:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":42,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":1066,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7390,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.51047,"AVALU":"mg/L","BASE2":8.85459,"BASE":10.59958,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.65588,"PCHG2":18.70086,"CHG":-0.08911,"PCHG":-0.8407,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"3","BTOXGR":"4","ADTM":"2021-06-01 14:23:21","ADY":761,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-126","SUBJID":"id-126","SITEID":"CHN-7","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.77455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-02","TRTSDTM":"2019-05-02 14:23:21","TRTEDTM":"2022-02-20 00:30:20","TRT01SDTM":"2019-05-02 14:23:21","TRT01EDTM":"2021-02-19 18:30:20","TRT02SDTM":"2021-02-19 18:30:20","TRT02EDTM":"2022-02-20 00:30:20","AP01SDTM":"2019-05-02 14:23:21","AP01EDTM":"2021-02-19 18:30:20","AP02SDTM":"2021-02-19 18:30:20","AP02EDTM":"2022-02-20 00:30:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":42,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":1066,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3632,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.22506,"AVALU":"mg/L","BASE2":8.85459,"BASE":10.59958,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.37047,"PCHG2":15.47755,"CHG":-0.37452,"PCHG":-3.53337,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"3","BTOXGR":"4","ADTM":"2021-09-29 14:23:21","ADY":881,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-126","SUBJID":"id-126","SITEID":"CHN-7","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.77455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-02","TRTSDTM":"2019-05-02 14:23:21","TRTEDTM":"2022-02-20 00:30:20","TRT01SDTM":"2019-05-02 14:23:21","TRT01EDTM":"2021-02-19 18:30:20","TRT02SDTM":"2021-02-19 18:30:20","TRT02EDTM":"2022-02-20 00:30:20","AP01SDTM":"2019-05-02 14:23:21","AP01EDTM":"2021-02-19 18:30:20","AP02SDTM":"2021-02-19 18:30:20","AP02EDTM":"2022-02-20 00:30:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":42,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":1066,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4121,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":12.49538,"AVALU":"mg/L","BASE2":8.85459,"BASE":10.59958,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.6408,"PCHG2":41.11761,"CHG":1.8958,"PCHG":17.8856,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"4","ADTM":"2021-11-10 14:23:21","ADY":923,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-126","SUBJID":"id-126","SITEID":"CHN-7","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.77455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-02","TRTSDTM":"2019-05-02 14:23:21","TRTEDTM":"2022-02-20 00:30:20","TRT01SDTM":"2019-05-02 14:23:21","TRT01EDTM":"2021-02-19 18:30:20","TRT02SDTM":"2021-02-19 18:30:20","TRT02EDTM":"2022-02-20 00:30:20","AP01SDTM":"2019-05-02 14:23:21","AP01EDTM":"2021-02-19 18:30:20","AP02SDTM":"2021-02-19 18:30:20","AP02EDTM":"2022-02-20 00:30:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":42,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":1066,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7075,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85793,"AVALU":"g/L","BASE2":2.85793,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-31 14:23:21","ADY":121,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-126","SUBJID":"id-126","SITEID":"CHN-7","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.77455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-02","TRTSDTM":"2019-05-02 14:23:21","TRTEDTM":"2022-02-20 00:30:20","TRT01SDTM":"2019-05-02 14:23:21","TRT01EDTM":"2021-02-19 18:30:20","TRT02SDTM":"2021-02-19 18:30:20","TRT02EDTM":"2022-02-20 00:30:20","AP01SDTM":"2019-05-02 14:23:21","AP01EDTM":"2021-02-19 18:30:20","AP02SDTM":"2021-02-19 18:30:20","AP02EDTM":"2022-02-20 00:30:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":42,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":1066,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6986,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77092,"AVALU":"g/L","BASE2":2.85793,"BASE":2.77092,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.08701,"PCHG2":-3.04435,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-02 14:23:21","ADY":336,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-126","SUBJID":"id-126","SITEID":"CHN-7","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.77455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-02","TRTSDTM":"2019-05-02 14:23:21","TRTEDTM":"2022-02-20 00:30:20","TRT01SDTM":"2019-05-02 14:23:21","TRT01EDTM":"2021-02-19 18:30:20","TRT02SDTM":"2021-02-19 18:30:20","TRT02EDTM":"2022-02-20 00:30:20","AP01SDTM":"2019-05-02 14:23:21","AP01EDTM":"2021-02-19 18:30:20","AP02SDTM":"2021-02-19 18:30:20","AP02EDTM":"2022-02-20 00:30:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":42,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":1066,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3673,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89369,"AVALU":"g/L","BASE2":2.85793,"BASE":2.77092,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03576,"PCHG2":1.25142,"CHG":0.12277,"PCHG":4.43065,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-15 14:23:21","ADY":379,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-126","SUBJID":"id-126","SITEID":"CHN-7","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.77455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-02","TRTSDTM":"2019-05-02 14:23:21","TRTEDTM":"2022-02-20 00:30:20","TRT01SDTM":"2019-05-02 14:23:21","TRT01EDTM":"2021-02-19 18:30:20","TRT02SDTM":"2021-02-19 18:30:20","TRT02EDTM":"2022-02-20 00:30:20","AP01SDTM":"2019-05-02 14:23:21","AP01EDTM":"2021-02-19 18:30:20","AP02SDTM":"2021-02-19 18:30:20","AP02EDTM":"2022-02-20 00:30:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":42,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":1066,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7320,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96227,"AVALU":"g/L","BASE2":2.85793,"BASE":2.77092,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10434,"PCHG2":3.65087,"CHG":0.19134,"PCHG":6.90545,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-27 14:23:21","ADY":514,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-126","SUBJID":"id-126","SITEID":"CHN-7","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.77455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-02","TRTSDTM":"2019-05-02 14:23:21","TRTEDTM":"2022-02-20 00:30:20","TRT01SDTM":"2019-05-02 14:23:21","TRT01EDTM":"2021-02-19 18:30:20","TRT02SDTM":"2021-02-19 18:30:20","TRT02EDTM":"2022-02-20 00:30:20","AP01SDTM":"2019-05-02 14:23:21","AP01EDTM":"2021-02-19 18:30:20","AP02SDTM":"2021-02-19 18:30:20","AP02EDTM":"2022-02-20 00:30:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":42,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":1066,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6431,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96765,"AVALU":"g/L","BASE2":2.85793,"BASE":2.77092,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10972,"PCHG2":3.83927,"CHG":0.19673,"PCHG":7.09976,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-01 14:23:21","ADY":761,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-126","SUBJID":"id-126","SITEID":"CHN-7","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.77455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-02","TRTSDTM":"2019-05-02 14:23:21","TRTEDTM":"2022-02-20 00:30:20","TRT01SDTM":"2019-05-02 14:23:21","TRT01EDTM":"2021-02-19 18:30:20","TRT02SDTM":"2021-02-19 18:30:20","TRT02EDTM":"2022-02-20 00:30:20","AP01SDTM":"2019-05-02 14:23:21","AP01EDTM":"2021-02-19 18:30:20","AP02SDTM":"2021-02-19 18:30:20","AP02EDTM":"2022-02-20 00:30:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":42,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":1066,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7954,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85547,"AVALU":"g/L","BASE2":2.85793,"BASE":2.77092,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00246,"PCHG2":-0.08607,"CHG":0.08455,"PCHG":3.05117,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-29 14:23:21","ADY":881,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-126","SUBJID":"id-126","SITEID":"CHN-7","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.77455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-02","TRTSDTM":"2019-05-02 14:23:21","TRTEDTM":"2022-02-20 00:30:20","TRT01SDTM":"2019-05-02 14:23:21","TRT01EDTM":"2021-02-19 18:30:20","TRT02SDTM":"2021-02-19 18:30:20","TRT02EDTM":"2022-02-20 00:30:20","AP01SDTM":"2019-05-02 14:23:21","AP01EDTM":"2021-02-19 18:30:20","AP02SDTM":"2021-02-19 18:30:20","AP02EDTM":"2022-02-20 00:30:20","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":42,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":1066,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5931,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93986,"AVALU":"g/L","BASE2":2.85793,"BASE":2.77092,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08193,"PCHG2":2.86663,"CHG":0.16893,"PCHG":6.09659,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-10 14:23:21","ADY":923,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-202","SUBJID":"id-202","SITEID":"CHN-7","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.5983,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-05","TRTSDTM":"2019-11-06 20:15:16","TRT01SDTM":"2019-11-06 20:15:16","AP01SDTM":"2019-11-06 20:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6855,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.6355,"AVALU":"U/L","BASE2":2.6355,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2019-12-19 20:15:16","ADY":43,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-202","SUBJID":"id-202","SITEID":"CHN-7","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.5983,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-05","TRTSDTM":"2019-11-06 20:15:16","TRT01SDTM":"2019-11-06 20:15:16","AP01SDTM":"2019-11-06 20:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6357,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.27991,"AVALU":"U/L","BASE2":2.6355,"BASE":21.27991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":18.64441,"PCHG2":707.43313,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-07 20:15:16","ADY":93,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-202","SUBJID":"id-202","SITEID":"CHN-7","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.5983,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-05","TRTSDTM":"2019-11-06 20:15:16","TRT01SDTM":"2019-11-06 20:15:16","AP01SDTM":"2019-11-06 20:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5141,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.87799,"AVALU":"U/L","BASE2":2.6355,"BASE":21.27991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.24249,"PCHG2":502.46559,"CHG":-5.40192,"PCHG":-25.38508,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-19 20:15:16","ADY":195,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-202","SUBJID":"id-202","SITEID":"CHN-7","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.5983,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-05","TRTSDTM":"2019-11-06 20:15:16","TRT01SDTM":"2019-11-06 20:15:16","AP01SDTM":"2019-11-06 20:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6272,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.52925,"AVALU":"U/L","BASE2":2.6355,"BASE":21.27991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.89375,"PCHG2":527.17663,"CHG":-4.75066,"PCHG":-22.32464,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-25 20:15:16","ADY":354,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-202","SUBJID":"id-202","SITEID":"CHN-7","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.5983,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-05","TRTSDTM":"2019-11-06 20:15:16","TRT01SDTM":"2019-11-06 20:15:16","AP01SDTM":"2019-11-06 20:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4145,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.31642,"AVALU":"U/L","BASE2":2.6355,"BASE":21.27991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.68092,"PCHG2":101.72339,"CHG":-15.96349,"PCHG":-75.01671,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-12-07 20:15:16","ADY":397,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-202","SUBJID":"id-202","SITEID":"CHN-7","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.5983,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-05","TRTSDTM":"2019-11-06 20:15:16","TRT01SDTM":"2019-11-06 20:15:16","AP01SDTM":"2019-11-06 20:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7607,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.22728,"AVALU":"U/L","BASE2":2.6355,"BASE":21.27991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":23.59177,"PCHG2":895.15303,"CHG":4.94736,"PCHG":23.24897,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-21 20:15:16","ADY":411,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-202","SUBJID":"id-202","SITEID":"CHN-7","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.5983,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-05","TRTSDTM":"2019-11-06 20:15:16","TRT01SDTM":"2019-11-06 20:15:16","AP01SDTM":"2019-11-06 20:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2445,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.41872,"AVALU":"U/L","BASE2":2.6355,"BASE":21.27991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.78322,"PCHG2":750.64324,"CHG":1.1388,"PCHG":5.35154,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-03 20:15:16","ADY":697,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-202","SUBJID":"id-202","SITEID":"CHN-7","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.5983,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-05","TRTSDTM":"2019-11-06 20:15:16","TRT01SDTM":"2019-11-06 20:15:16","AP01SDTM":"2019-11-06 20:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7979,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.52725,"AVALU":"mg/L","BASE2":9.52725,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-19 20:15:16","ADY":43,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-202","SUBJID":"id-202","SITEID":"CHN-7","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.5983,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-05","TRTSDTM":"2019-11-06 20:15:16","TRT01SDTM":"2019-11-06 20:15:16","AP01SDTM":"2019-11-06 20:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6464,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.59522,"AVALU":"mg/L","BASE2":9.52725,"BASE":9.59522,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.06797,"PCHG2":0.71347,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-07 20:15:16","ADY":93,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-202","SUBJID":"id-202","SITEID":"CHN-7","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.5983,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-05","TRTSDTM":"2019-11-06 20:15:16","TRT01SDTM":"2019-11-06 20:15:16","AP01SDTM":"2019-11-06 20:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5799,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.23023,"AVALU":"mg/L","BASE2":9.52725,"BASE":9.59522,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.29702,"PCHG2":-3.1176,"CHG":-0.365,"PCHG":-3.80392,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-19 20:15:16","ADY":195,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-202","SUBJID":"id-202","SITEID":"CHN-7","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.5983,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-05","TRTSDTM":"2019-11-06 20:15:16","TRT01SDTM":"2019-11-06 20:15:16","AP01SDTM":"2019-11-06 20:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4655,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.97362,"AVALU":"mg/L","BASE2":9.52725,"BASE":9.59522,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.55363,"PCHG2":-5.811,"CHG":-0.6216,"PCHG":-6.47825,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-25 20:15:16","ADY":354,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-202","SUBJID":"id-202","SITEID":"CHN-7","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.5983,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-05","TRTSDTM":"2019-11-06 20:15:16","TRT01SDTM":"2019-11-06 20:15:16","AP01SDTM":"2019-11-06 20:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4573,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.87946,"AVALU":"mg/L","BASE2":9.52725,"BASE":9.59522,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.35221,"PCHG2":3.69684,"CHG":0.28423,"PCHG":2.96224,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-07 20:15:16","ADY":397,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-202","SUBJID":"id-202","SITEID":"CHN-7","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.5983,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-05","TRTSDTM":"2019-11-06 20:15:16","TRT01SDTM":"2019-11-06 20:15:16","AP01SDTM":"2019-11-06 20:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8095,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.22683,"AVALU":"mg/L","BASE2":9.52725,"BASE":9.59522,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.30042,"PCHG2":-3.15323,"CHG":-0.36839,"PCHG":-3.8393,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-21 20:15:16","ADY":411,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-202","SUBJID":"id-202","SITEID":"CHN-7","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.5983,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-05","TRTSDTM":"2019-11-06 20:15:16","TRT01SDTM":"2019-11-06 20:15:16","AP01SDTM":"2019-11-06 20:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4182,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.8495,"AVALU":"mg/L","BASE2":9.52725,"BASE":9.59522,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.32225,"PCHG2":3.3824,"CHG":0.25428,"PCHG":2.65002,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-03 20:15:16","ADY":697,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-202","SUBJID":"id-202","SITEID":"CHN-7","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.5983,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-05","TRTSDTM":"2019-11-06 20:15:16","TRT01SDTM":"2019-11-06 20:15:16","AP01SDTM":"2019-11-06 20:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7355,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.65202,"AVALU":"g/L","BASE2":2.65202,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-19 20:15:16","ADY":43,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-202","SUBJID":"id-202","SITEID":"CHN-7","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.5983,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-05","TRTSDTM":"2019-11-06 20:15:16","TRT01SDTM":"2019-11-06 20:15:16","AP01SDTM":"2019-11-06 20:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4367,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86869,"AVALU":"g/L","BASE2":2.65202,"BASE":2.86869,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.21666,"PCHG2":8.16974,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-07 20:15:16","ADY":93,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-202","SUBJID":"id-202","SITEID":"CHN-7","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.5983,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-05","TRTSDTM":"2019-11-06 20:15:16","TRT01SDTM":"2019-11-06 20:15:16","AP01SDTM":"2019-11-06 20:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6773,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89745,"AVALU":"g/L","BASE2":2.65202,"BASE":2.86869,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.24543,"PCHG2":9.25427,"CHG":0.02876,"PCHG":1.00262,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-19 20:15:16","ADY":195,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-202","SUBJID":"id-202","SITEID":"CHN-7","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.5983,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-05","TRTSDTM":"2019-11-06 20:15:16","TRT01SDTM":"2019-11-06 20:15:16","AP01SDTM":"2019-11-06 20:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6207,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93718,"AVALU":"g/L","BASE2":2.65202,"BASE":2.86869,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.28516,"PCHG2":10.75257,"CHG":0.0685,"PCHG":2.38776,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-25 20:15:16","ADY":354,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-202","SUBJID":"id-202","SITEID":"CHN-7","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.5983,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-05","TRTSDTM":"2019-11-06 20:15:16","TRT01SDTM":"2019-11-06 20:15:16","AP01SDTM":"2019-11-06 20:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3940,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81806,"AVALU":"g/L","BASE2":2.65202,"BASE":2.86869,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16603,"PCHG2":6.2606,"CHG":-0.05063,"PCHG":-1.76495,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-07 20:15:16","ADY":397,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-202","SUBJID":"id-202","SITEID":"CHN-7","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.5983,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-05","TRTSDTM":"2019-11-06 20:15:16","TRT01SDTM":"2019-11-06 20:15:16","AP01SDTM":"2019-11-06 20:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4629,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81231,"AVALU":"g/L","BASE2":2.65202,"BASE":2.86869,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16028,"PCHG2":6.04387,"CHG":-0.05638,"PCHG":-1.96531,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-21 20:15:16","ADY":411,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-202","SUBJID":"id-202","SITEID":"CHN-7","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.5983,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-05","TRTSDTM":"2019-11-06 20:15:16","TRT01SDTM":"2019-11-06 20:15:16","AP01SDTM":"2019-11-06 20:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":29,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84609,"AVALU":"g/L","BASE2":2.65202,"BASE":2.86869,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.19406,"PCHG2":7.31755,"CHG":-0.0226,"PCHG":-0.78783,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-03 20:15:16","ADY":697,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-267","SUBJID":"id-267","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.20676,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-01","TRTSDTM":"2019-03-02 00:09:33","TRTEDTM":"2022-03-01 18:09:33","TRT01SDTM":"2019-03-02 00:09:33","TRT01EDTM":"2021-03-01 12:09:33","TRT02SDTM":"2021-03-01 12:09:33","TRT02EDTM":"2022-03-01 18:09:33","AP01SDTM":"2019-03-02 00:09:33","AP01EDTM":"2021-03-01 12:09:33","AP02SDTM":"2021-03-01 12:09:33","AP02EDTM":"2022-03-01 18:09:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-15","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1847,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.29508,"AVALU":"U/L","BASE2":21.29508,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-05-26 00:09:33","ADY":85,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-267","SUBJID":"id-267","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.20676,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-01","TRTSDTM":"2019-03-02 00:09:33","TRTEDTM":"2022-03-01 18:09:33","TRT01SDTM":"2019-03-02 00:09:33","TRT01EDTM":"2021-03-01 12:09:33","TRT02SDTM":"2021-03-01 12:09:33","TRT02EDTM":"2022-03-01 18:09:33","AP01SDTM":"2019-03-02 00:09:33","AP01EDTM":"2021-03-01 12:09:33","AP02SDTM":"2021-03-01 12:09:33","AP02EDTM":"2022-03-01 18:09:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-15","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":979,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.97649,"AVALU":"U/L","BASE2":21.29508,"BASE":24.97649,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":3.68141,"PCHG2":17.2876,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-16 00:09:33","ADY":259,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-267","SUBJID":"id-267","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.20676,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-01","TRTSDTM":"2019-03-02 00:09:33","TRTEDTM":"2022-03-01 18:09:33","TRT01SDTM":"2019-03-02 00:09:33","TRT01EDTM":"2021-03-01 12:09:33","TRT02SDTM":"2021-03-01 12:09:33","TRT02EDTM":"2022-03-01 18:09:33","AP01SDTM":"2019-03-02 00:09:33","AP01EDTM":"2021-03-01 12:09:33","AP02SDTM":"2021-03-01 12:09:33","AP02EDTM":"2022-03-01 18:09:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-15","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5971,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.60049,"AVALU":"U/L","BASE2":21.29508,"BASE":24.97649,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.30541,"PCHG2":10.82602,"CHG":-1.376,"PCHG":-5.50918,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-10 00:09:33","ADY":283,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-267","SUBJID":"id-267","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.20676,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-01","TRTSDTM":"2019-03-02 00:09:33","TRTEDTM":"2022-03-01 18:09:33","TRT01SDTM":"2019-03-02 00:09:33","TRT01EDTM":"2021-03-01 12:09:33","TRT02SDTM":"2021-03-01 12:09:33","TRT02EDTM":"2022-03-01 18:09:33","AP01SDTM":"2019-03-02 00:09:33","AP01EDTM":"2021-03-01 12:09:33","AP02SDTM":"2021-03-01 12:09:33","AP02EDTM":"2022-03-01 18:09:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-15","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7831,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.03633,"AVALU":"U/L","BASE2":21.29508,"BASE":24.97649,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.74125,"PCHG2":17.56863,"CHG":0.05985,"PCHG":0.23961,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-05 00:09:33","ADY":340,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-267","SUBJID":"id-267","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.20676,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-01","TRTSDTM":"2019-03-02 00:09:33","TRTEDTM":"2022-03-01 18:09:33","TRT01SDTM":"2019-03-02 00:09:33","TRT01EDTM":"2021-03-01 12:09:33","TRT02SDTM":"2021-03-01 12:09:33","TRT02EDTM":"2022-03-01 18:09:33","AP01SDTM":"2019-03-02 00:09:33","AP01EDTM":"2021-03-01 12:09:33","AP02SDTM":"2021-03-01 12:09:33","AP02EDTM":"2022-03-01 18:09:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-15","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2156,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.71546,"AVALU":"U/L","BASE2":21.29508,"BASE":24.97649,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.57961,"PCHG2":-30.89735,"CHG":-10.26102,"PCHG":-41.08273,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-02 00:09:33","ADY":458,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-267","SUBJID":"id-267","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.20676,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-01","TRTSDTM":"2019-03-02 00:09:33","TRTEDTM":"2022-03-01 18:09:33","TRT01SDTM":"2019-03-02 00:09:33","TRT01EDTM":"2021-03-01 12:09:33","TRT02SDTM":"2021-03-01 12:09:33","TRT02EDTM":"2022-03-01 18:09:33","AP01SDTM":"2019-03-02 00:09:33","AP01EDTM":"2021-03-01 12:09:33","AP02SDTM":"2021-03-01 12:09:33","AP02EDTM":"2022-03-01 18:09:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-15","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":285,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.39602,"AVALU":"U/L","BASE2":21.29508,"BASE":24.97649,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.89906,"PCHG2":-27.70153,"CHG":-9.58047,"PCHG":-38.35796,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-22 00:09:33","ADY":723,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-267","SUBJID":"id-267","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.20676,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-01","TRTSDTM":"2019-03-02 00:09:33","TRTEDTM":"2022-03-01 18:09:33","TRT01SDTM":"2019-03-02 00:09:33","TRT01EDTM":"2021-03-01 12:09:33","TRT02SDTM":"2021-03-01 12:09:33","TRT02EDTM":"2022-03-01 18:09:33","AP01SDTM":"2019-03-02 00:09:33","AP01EDTM":"2021-03-01 12:09:33","AP02SDTM":"2021-03-01 12:09:33","AP02EDTM":"2022-03-01 18:09:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-15","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7506,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.75058,"AVALU":"U/L","BASE2":21.29508,"BASE":24.97649,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.5445,"PCHG2":-16.64467,"CHG":-7.2259,"PCHG":-28.93082,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-09 00:09:33","ADY":952,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-267","SUBJID":"id-267","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.20676,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-01","TRTSDTM":"2019-03-02 00:09:33","TRTEDTM":"2022-03-01 18:09:33","TRT01SDTM":"2019-03-02 00:09:33","TRT01EDTM":"2021-03-01 12:09:33","TRT02SDTM":"2021-03-01 12:09:33","TRT02EDTM":"2022-03-01 18:09:33","AP01SDTM":"2019-03-02 00:09:33","AP01EDTM":"2021-03-01 12:09:33","AP02SDTM":"2021-03-01 12:09:33","AP02EDTM":"2022-03-01 18:09:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-15","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":527,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.56581,"AVALU":"mg/L","BASE2":9.56581,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-05-26 00:09:33","ADY":85,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-267","SUBJID":"id-267","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.20676,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-01","TRTSDTM":"2019-03-02 00:09:33","TRTEDTM":"2022-03-01 18:09:33","TRT01SDTM":"2019-03-02 00:09:33","TRT01EDTM":"2021-03-01 12:09:33","TRT02SDTM":"2021-03-01 12:09:33","TRT02EDTM":"2022-03-01 18:09:33","AP01SDTM":"2019-03-02 00:09:33","AP01EDTM":"2021-03-01 12:09:33","AP02SDTM":"2021-03-01 12:09:33","AP02EDTM":"2022-03-01 18:09:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-15","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1565,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.49956,"AVALU":"mg/L","BASE2":9.56581,"BASE":8.49956,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.06625,"PCHG2":-11.14643,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-16 00:09:33","ADY":259,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-267","SUBJID":"id-267","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.20676,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-01","TRTSDTM":"2019-03-02 00:09:33","TRTEDTM":"2022-03-01 18:09:33","TRT01SDTM":"2019-03-02 00:09:33","TRT01EDTM":"2021-03-01 12:09:33","TRT02SDTM":"2021-03-01 12:09:33","TRT02EDTM":"2022-03-01 18:09:33","AP01SDTM":"2019-03-02 00:09:33","AP01EDTM":"2021-03-01 12:09:33","AP02SDTM":"2021-03-01 12:09:33","AP02EDTM":"2022-03-01 18:09:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-15","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1403,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.56642,"AVALU":"mg/L","BASE2":9.56581,"BASE":8.49956,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.99938,"PCHG2":-10.44745,"CHG":0.06686,"PCHG":0.78667,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-10 00:09:33","ADY":283,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-267","SUBJID":"id-267","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.20676,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-01","TRTSDTM":"2019-03-02 00:09:33","TRTEDTM":"2022-03-01 18:09:33","TRT01SDTM":"2019-03-02 00:09:33","TRT01EDTM":"2021-03-01 12:09:33","TRT02SDTM":"2021-03-01 12:09:33","TRT02EDTM":"2022-03-01 18:09:33","AP01SDTM":"2019-03-02 00:09:33","AP01EDTM":"2021-03-01 12:09:33","AP02SDTM":"2021-03-01 12:09:33","AP02EDTM":"2022-03-01 18:09:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-15","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1274,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.8715,"AVALU":"mg/L","BASE2":9.56581,"BASE":8.49956,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.3057,"PCHG2":3.19572,"CHG":1.37194,"PCHG":16.14133,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-05 00:09:33","ADY":340,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-267","SUBJID":"id-267","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.20676,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-01","TRTSDTM":"2019-03-02 00:09:33","TRTEDTM":"2022-03-01 18:09:33","TRT01SDTM":"2019-03-02 00:09:33","TRT01EDTM":"2021-03-01 12:09:33","TRT02SDTM":"2021-03-01 12:09:33","TRT02EDTM":"2022-03-01 18:09:33","AP01SDTM":"2019-03-02 00:09:33","AP01EDTM":"2021-03-01 12:09:33","AP02SDTM":"2021-03-01 12:09:33","AP02EDTM":"2022-03-01 18:09:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-15","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2139,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.85768,"AVALU":"mg/L","BASE2":9.56581,"BASE":8.49956,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.70812,"PCHG2":-7.40265,"CHG":0.35812,"PCHG":4.21343,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-02 00:09:33","ADY":458,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-267","SUBJID":"id-267","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.20676,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-01","TRTSDTM":"2019-03-02 00:09:33","TRTEDTM":"2022-03-01 18:09:33","TRT01SDTM":"2019-03-02 00:09:33","TRT01EDTM":"2021-03-01 12:09:33","TRT02SDTM":"2021-03-01 12:09:33","TRT02EDTM":"2022-03-01 18:09:33","AP01SDTM":"2019-03-02 00:09:33","AP01EDTM":"2021-03-01 12:09:33","AP02SDTM":"2021-03-01 12:09:33","AP02EDTM":"2022-03-01 18:09:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-15","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":261,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.77408,"AVALU":"mg/L","BASE2":9.56581,"BASE":8.49956,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.79173,"PCHG2":-8.27666,"CHG":0.27452,"PCHG":3.22978,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-22 00:09:33","ADY":723,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-267","SUBJID":"id-267","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.20676,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-01","TRTSDTM":"2019-03-02 00:09:33","TRTEDTM":"2022-03-01 18:09:33","TRT01SDTM":"2019-03-02 00:09:33","TRT01EDTM":"2021-03-01 12:09:33","TRT02SDTM":"2021-03-01 12:09:33","TRT02EDTM":"2022-03-01 18:09:33","AP01SDTM":"2019-03-02 00:09:33","AP01EDTM":"2021-03-01 12:09:33","AP02SDTM":"2021-03-01 12:09:33","AP02EDTM":"2022-03-01 18:09:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-15","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1067,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.85886,"AVALU":"mg/L","BASE2":9.56581,"BASE":8.49956,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.70695,"PCHG2":-17.84427,"CHG":-0.6407,"PCHG":-7.53806,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-10-09 00:09:33","ADY":952,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-267","SUBJID":"id-267","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.20676,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-01","TRTSDTM":"2019-03-02 00:09:33","TRTEDTM":"2022-03-01 18:09:33","TRT01SDTM":"2019-03-02 00:09:33","TRT01EDTM":"2021-03-01 12:09:33","TRT02SDTM":"2021-03-01 12:09:33","TRT02EDTM":"2022-03-01 18:09:33","AP01SDTM":"2019-03-02 00:09:33","AP01EDTM":"2021-03-01 12:09:33","AP02SDTM":"2021-03-01 12:09:33","AP02EDTM":"2022-03-01 18:09:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-15","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":280,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93079,"AVALU":"g/L","BASE2":2.93079,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-05-26 00:09:33","ADY":85,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-267","SUBJID":"id-267","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.20676,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-01","TRTSDTM":"2019-03-02 00:09:33","TRTEDTM":"2022-03-01 18:09:33","TRT01SDTM":"2019-03-02 00:09:33","TRT01EDTM":"2021-03-01 12:09:33","TRT02SDTM":"2021-03-01 12:09:33","TRT02EDTM":"2022-03-01 18:09:33","AP01SDTM":"2019-03-02 00:09:33","AP01EDTM":"2021-03-01 12:09:33","AP02SDTM":"2021-03-01 12:09:33","AP02EDTM":"2022-03-01 18:09:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-15","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1877,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81489,"AVALU":"g/L","BASE2":2.93079,"BASE":2.81489,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.11591,"PCHG2":-3.9548,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-16 00:09:33","ADY":259,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-267","SUBJID":"id-267","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.20676,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-01","TRTSDTM":"2019-03-02 00:09:33","TRTEDTM":"2022-03-01 18:09:33","TRT01SDTM":"2019-03-02 00:09:33","TRT01EDTM":"2021-03-01 12:09:33","TRT02SDTM":"2021-03-01 12:09:33","TRT02EDTM":"2022-03-01 18:09:33","AP01SDTM":"2019-03-02 00:09:33","AP01EDTM":"2021-03-01 12:09:33","AP02SDTM":"2021-03-01 12:09:33","AP02EDTM":"2022-03-01 18:09:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-15","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":233,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00387,"AVALU":"g/L","BASE2":2.93079,"BASE":2.81489,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07308,"PCHG2":2.49336,"CHG":0.18898,"PCHG":6.71366,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2019-12-10 00:09:33","ADY":283,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-267","SUBJID":"id-267","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.20676,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-01","TRTSDTM":"2019-03-02 00:09:33","TRTEDTM":"2022-03-01 18:09:33","TRT01SDTM":"2019-03-02 00:09:33","TRT01EDTM":"2021-03-01 12:09:33","TRT02SDTM":"2021-03-01 12:09:33","TRT02EDTM":"2022-03-01 18:09:33","AP01SDTM":"2019-03-02 00:09:33","AP01EDTM":"2021-03-01 12:09:33","AP02SDTM":"2021-03-01 12:09:33","AP02EDTM":"2022-03-01 18:09:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-15","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3450,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9958,"AVALU":"g/L","BASE2":2.93079,"BASE":2.81489,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06501,"PCHG2":2.218,"CHG":0.18091,"PCHG":6.42697,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-05 00:09:33","ADY":340,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-267","SUBJID":"id-267","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.20676,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-01","TRTSDTM":"2019-03-02 00:09:33","TRTEDTM":"2022-03-01 18:09:33","TRT01SDTM":"2019-03-02 00:09:33","TRT01EDTM":"2021-03-01 12:09:33","TRT02SDTM":"2021-03-01 12:09:33","TRT02EDTM":"2022-03-01 18:09:33","AP01SDTM":"2019-03-02 00:09:33","AP01EDTM":"2021-03-01 12:09:33","AP02SDTM":"2021-03-01 12:09:33","AP02EDTM":"2022-03-01 18:09:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-15","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2737,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84662,"AVALU":"g/L","BASE2":2.93079,"BASE":2.81489,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08418,"PCHG2":-2.87212,"CHG":0.03173,"PCHG":1.12725,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-02 00:09:33","ADY":458,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-267","SUBJID":"id-267","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.20676,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-01","TRTSDTM":"2019-03-02 00:09:33","TRTEDTM":"2022-03-01 18:09:33","TRT01SDTM":"2019-03-02 00:09:33","TRT01EDTM":"2021-03-01 12:09:33","TRT02SDTM":"2021-03-01 12:09:33","TRT02EDTM":"2022-03-01 18:09:33","AP01SDTM":"2019-03-02 00:09:33","AP01EDTM":"2021-03-01 12:09:33","AP02SDTM":"2021-03-01 12:09:33","AP02EDTM":"2022-03-01 18:09:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-15","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1512,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93051,"AVALU":"g/L","BASE2":2.93079,"BASE":2.81489,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00028,"PCHG2":-0.00967,"CHG":0.11562,"PCHG":4.10758,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-22 00:09:33","ADY":723,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-267","SUBJID":"id-267","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.20676,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-01","TRTSDTM":"2019-03-02 00:09:33","TRTEDTM":"2022-03-01 18:09:33","TRT01SDTM":"2019-03-02 00:09:33","TRT01EDTM":"2021-03-01 12:09:33","TRT02SDTM":"2021-03-01 12:09:33","TRT02EDTM":"2022-03-01 18:09:33","AP01SDTM":"2019-03-02 00:09:33","AP01EDTM":"2021-03-01 12:09:33","AP02SDTM":"2021-03-01 12:09:33","AP02EDTM":"2022-03-01 18:09:33","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-01","EOSDY":1096,"LSTALVDT":"2022-03-15","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6533,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76029,"AVALU":"g/L","BASE2":2.93079,"BASE":2.81489,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1705,"PCHG2":-5.81768,"CHG":-0.0546,"PCHG":-1.93959,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-09 00:09:33","ADY":952,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-28","SUBJID":"id-28","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.14445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-10","TRTSDTM":"2019-03-11 09:11:52","TRTEDTM":"2022-03-11 03:11:52","TRT01SDTM":"2019-03-11 09:11:52","TRT01EDTM":"2021-03-10 21:11:52","TRT02SDTM":"2021-03-10 21:11:52","TRT02EDTM":"2022-03-11 03:11:52","AP01SDTM":"2019-03-11 09:11:52","AP01EDTM":"2021-03-10 21:11:52","AP02SDTM":"2021-03-10 21:11:52","AP02EDTM":"2022-03-11 03:11:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-11","EOSDY":1096,"LSTALVDT":"2022-03-31","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3585,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.11781,"AVALU":"U/L","BASE2":33.11781,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-1","ADTM":"2019-08-19 09:11:52","ADY":161,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-28","SUBJID":"id-28","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.14445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-10","TRTSDTM":"2019-03-11 09:11:52","TRTEDTM":"2022-03-11 03:11:52","TRT01SDTM":"2019-03-11 09:11:52","TRT01EDTM":"2021-03-10 21:11:52","TRT02SDTM":"2021-03-10 21:11:52","TRT02EDTM":"2022-03-11 03:11:52","AP01SDTM":"2019-03-11 09:11:52","AP01EDTM":"2021-03-10 21:11:52","AP02SDTM":"2021-03-10 21:11:52","AP02EDTM":"2022-03-11 03:11:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-11","EOSDY":1096,"LSTALVDT":"2022-03-31","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6003,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.09445,"AVALU":"U/L","BASE2":33.11781,"BASE":2.09445,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-31.02336,"PCHG2":-93.67576,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2020-03-10 09:11:52","ADY":365,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-28","SUBJID":"id-28","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.14445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-10","TRTSDTM":"2019-03-11 09:11:52","TRTEDTM":"2022-03-11 03:11:52","TRT01SDTM":"2019-03-11 09:11:52","TRT01EDTM":"2021-03-10 21:11:52","TRT02SDTM":"2021-03-10 21:11:52","TRT02EDTM":"2022-03-11 03:11:52","AP01SDTM":"2019-03-11 09:11:52","AP01EDTM":"2021-03-10 21:11:52","AP02SDTM":"2021-03-10 21:11:52","AP02EDTM":"2022-03-11 03:11:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-11","EOSDY":1096,"LSTALVDT":"2022-03-31","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5705,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.34955,"AVALU":"U/L","BASE2":33.11781,"BASE":2.09445,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.76826,"PCHG2":-50.63216,"CHG":14.2551,"PCHG":680.61353,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-11-14 09:11:52","ADY":614,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-28","SUBJID":"id-28","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.14445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-10","TRTSDTM":"2019-03-11 09:11:52","TRTEDTM":"2022-03-11 03:11:52","TRT01SDTM":"2019-03-11 09:11:52","TRT01EDTM":"2021-03-10 21:11:52","TRT02SDTM":"2021-03-10 21:11:52","TRT02EDTM":"2022-03-11 03:11:52","AP01SDTM":"2019-03-11 09:11:52","AP01EDTM":"2021-03-10 21:11:52","AP02SDTM":"2021-03-10 21:11:52","AP02EDTM":"2022-03-11 03:11:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-11","EOSDY":1096,"LSTALVDT":"2022-03-31","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7459,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.93723,"AVALU":"U/L","BASE2":33.11781,"BASE":2.09445,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-15.18058,"PCHG2":-45.83811,"CHG":15.84278,"PCHG":756.41795,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-04-09 09:11:52","ADY":760,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-28","SUBJID":"id-28","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.14445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-10","TRTSDTM":"2019-03-11 09:11:52","TRTEDTM":"2022-03-11 03:11:52","TRT01SDTM":"2019-03-11 09:11:52","TRT01EDTM":"2021-03-10 21:11:52","TRT02SDTM":"2021-03-10 21:11:52","TRT02EDTM":"2022-03-11 03:11:52","AP01SDTM":"2019-03-11 09:11:52","AP01EDTM":"2021-03-10 21:11:52","AP02SDTM":"2021-03-10 21:11:52","AP02EDTM":"2022-03-11 03:11:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-11","EOSDY":1096,"LSTALVDT":"2022-03-31","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6223,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.60509,"AVALU":"U/L","BASE2":33.11781,"BASE":2.09445,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.51272,"PCHG2":-25.70435,"CHG":22.51064,"PCHG":1074.77666,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-05-31 09:11:52","ADY":812,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-28","SUBJID":"id-28","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.14445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-10","TRTSDTM":"2019-03-11 09:11:52","TRTEDTM":"2022-03-11 03:11:52","TRT01SDTM":"2019-03-11 09:11:52","TRT01EDTM":"2021-03-10 21:11:52","TRT02SDTM":"2021-03-10 21:11:52","TRT02EDTM":"2022-03-11 03:11:52","AP01SDTM":"2019-03-11 09:11:52","AP01EDTM":"2021-03-10 21:11:52","AP02SDTM":"2021-03-10 21:11:52","AP02EDTM":"2022-03-11 03:11:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-11","EOSDY":1096,"LSTALVDT":"2022-03-31","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2695,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.60592,"AVALU":"U/L","BASE2":33.11781,"BASE":2.09445,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-25.51189,"PCHG2":-77.03376,"CHG":5.51147,"PCHG":263.14652,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-12-13 09:11:52","ADY":1008,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-28","SUBJID":"id-28","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.14445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-10","TRTSDTM":"2019-03-11 09:11:52","TRTEDTM":"2022-03-11 03:11:52","TRT01SDTM":"2019-03-11 09:11:52","TRT01EDTM":"2021-03-10 21:11:52","TRT02SDTM":"2021-03-10 21:11:52","TRT02EDTM":"2022-03-11 03:11:52","AP01SDTM":"2019-03-11 09:11:52","AP01EDTM":"2021-03-10 21:11:52","AP02SDTM":"2021-03-10 21:11:52","AP02EDTM":"2022-03-11 03:11:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-11","EOSDY":1096,"LSTALVDT":"2022-03-31","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6365,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.5057,"AVALU":"U/L","BASE2":33.11781,"BASE":2.09445,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.61212,"PCHG2":-29.02401,"CHG":21.41125,"PCHG":1022.2857,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-12-19 09:11:52","ADY":1014,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-28","SUBJID":"id-28","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.14445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-10","TRTSDTM":"2019-03-11 09:11:52","TRTEDTM":"2022-03-11 03:11:52","TRT01SDTM":"2019-03-11 09:11:52","TRT01EDTM":"2021-03-10 21:11:52","TRT02SDTM":"2021-03-10 21:11:52","TRT02EDTM":"2022-03-11 03:11:52","AP01SDTM":"2019-03-11 09:11:52","AP01EDTM":"2021-03-10 21:11:52","AP02SDTM":"2021-03-10 21:11:52","AP02EDTM":"2022-03-11 03:11:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-11","EOSDY":1096,"LSTALVDT":"2022-03-31","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3127,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.73752,"AVALU":"mg/L","BASE2":8.73752,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-19 09:11:52","ADY":161,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-28","SUBJID":"id-28","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.14445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-10","TRTSDTM":"2019-03-11 09:11:52","TRTEDTM":"2022-03-11 03:11:52","TRT01SDTM":"2019-03-11 09:11:52","TRT01EDTM":"2021-03-10 21:11:52","TRT02SDTM":"2021-03-10 21:11:52","TRT02EDTM":"2022-03-11 03:11:52","AP01SDTM":"2019-03-11 09:11:52","AP01EDTM":"2021-03-10 21:11:52","AP02SDTM":"2021-03-10 21:11:52","AP02EDTM":"2022-03-11 03:11:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-11","EOSDY":1096,"LSTALVDT":"2022-03-31","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4610,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.35092,"AVALU":"mg/L","BASE2":8.73752,"BASE":9.35092,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.6134,"PCHG2":7.02034,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-10 09:11:52","ADY":365,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-28","SUBJID":"id-28","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.14445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-10","TRTSDTM":"2019-03-11 09:11:52","TRTEDTM":"2022-03-11 03:11:52","TRT01SDTM":"2019-03-11 09:11:52","TRT01EDTM":"2021-03-10 21:11:52","TRT02SDTM":"2021-03-10 21:11:52","TRT02EDTM":"2022-03-11 03:11:52","AP01SDTM":"2019-03-11 09:11:52","AP01EDTM":"2021-03-10 21:11:52","AP02SDTM":"2021-03-10 21:11:52","AP02EDTM":"2022-03-11 03:11:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-11","EOSDY":1096,"LSTALVDT":"2022-03-31","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7854,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.70251,"AVALU":"mg/L","BASE2":8.73752,"BASE":9.35092,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.96499,"PCHG2":11.04421,"CHG":0.35159,"PCHG":3.75992,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-14 09:11:52","ADY":614,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-28","SUBJID":"id-28","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.14445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-10","TRTSDTM":"2019-03-11 09:11:52","TRTEDTM":"2022-03-11 03:11:52","TRT01SDTM":"2019-03-11 09:11:52","TRT01EDTM":"2021-03-10 21:11:52","TRT02SDTM":"2021-03-10 21:11:52","TRT02EDTM":"2022-03-11 03:11:52","AP01SDTM":"2019-03-11 09:11:52","AP01EDTM":"2021-03-10 21:11:52","AP02SDTM":"2021-03-10 21:11:52","AP02EDTM":"2022-03-11 03:11:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-11","EOSDY":1096,"LSTALVDT":"2022-03-31","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":289,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.12151,"AVALU":"mg/L","BASE2":8.73752,"BASE":9.35092,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.38399,"PCHG2":4.39475,"CHG":-0.22941,"PCHG":-2.45335,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-09 09:11:52","ADY":760,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-28","SUBJID":"id-28","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.14445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-10","TRTSDTM":"2019-03-11 09:11:52","TRTEDTM":"2022-03-11 03:11:52","TRT01SDTM":"2019-03-11 09:11:52","TRT01EDTM":"2021-03-10 21:11:52","TRT02SDTM":"2021-03-10 21:11:52","TRT02EDTM":"2022-03-11 03:11:52","AP01SDTM":"2019-03-11 09:11:52","AP01EDTM":"2021-03-10 21:11:52","AP02SDTM":"2021-03-10 21:11:52","AP02EDTM":"2022-03-11 03:11:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-11","EOSDY":1096,"LSTALVDT":"2022-03-31","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2502,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.21392,"AVALU":"mg/L","BASE2":8.73752,"BASE":9.35092,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.4764,"PCHG2":16.89726,"CHG":0.863,"PCHG":9.22901,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2021-05-31 09:11:52","ADY":812,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-28","SUBJID":"id-28","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.14445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-10","TRTSDTM":"2019-03-11 09:11:52","TRTEDTM":"2022-03-11 03:11:52","TRT01SDTM":"2019-03-11 09:11:52","TRT01EDTM":"2021-03-10 21:11:52","TRT02SDTM":"2021-03-10 21:11:52","TRT02EDTM":"2022-03-11 03:11:52","AP01SDTM":"2019-03-11 09:11:52","AP01EDTM":"2021-03-10 21:11:52","AP02SDTM":"2021-03-10 21:11:52","AP02EDTM":"2022-03-11 03:11:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-11","EOSDY":1096,"LSTALVDT":"2022-03-31","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2281,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.21213,"AVALU":"mg/L","BASE2":8.73752,"BASE":9.35092,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.52538,"PCHG2":-6.01296,"CHG":-1.13879,"PCHG":-12.17834,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-13 09:11:52","ADY":1008,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-28","SUBJID":"id-28","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.14445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-10","TRTSDTM":"2019-03-11 09:11:52","TRTEDTM":"2022-03-11 03:11:52","TRT01SDTM":"2019-03-11 09:11:52","TRT01EDTM":"2021-03-10 21:11:52","TRT02SDTM":"2021-03-10 21:11:52","TRT02EDTM":"2022-03-11 03:11:52","AP01SDTM":"2019-03-11 09:11:52","AP01EDTM":"2021-03-10 21:11:52","AP02SDTM":"2021-03-10 21:11:52","AP02EDTM":"2022-03-11 03:11:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-11","EOSDY":1096,"LSTALVDT":"2022-03-31","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6670,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.69386,"AVALU":"mg/L","BASE2":8.73752,"BASE":9.35092,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.95634,"PCHG2":10.94521,"CHG":0.34294,"PCHG":3.66741,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-19 09:11:52","ADY":1014,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-28","SUBJID":"id-28","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.14445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-10","TRTSDTM":"2019-03-11 09:11:52","TRTEDTM":"2022-03-11 03:11:52","TRT01SDTM":"2019-03-11 09:11:52","TRT01EDTM":"2021-03-10 21:11:52","TRT02SDTM":"2021-03-10 21:11:52","TRT02EDTM":"2022-03-11 03:11:52","AP01SDTM":"2019-03-11 09:11:52","AP01EDTM":"2021-03-10 21:11:52","AP02SDTM":"2021-03-10 21:11:52","AP02EDTM":"2022-03-11 03:11:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-11","EOSDY":1096,"LSTALVDT":"2022-03-31","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6837,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81025,"AVALU":"g/L","BASE2":2.81025,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-19 09:11:52","ADY":161,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-28","SUBJID":"id-28","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.14445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-10","TRTSDTM":"2019-03-11 09:11:52","TRTEDTM":"2022-03-11 03:11:52","TRT01SDTM":"2019-03-11 09:11:52","TRT01EDTM":"2021-03-10 21:11:52","TRT02SDTM":"2021-03-10 21:11:52","TRT02EDTM":"2022-03-11 03:11:52","AP01SDTM":"2019-03-11 09:11:52","AP01EDTM":"2021-03-10 21:11:52","AP02SDTM":"2021-03-10 21:11:52","AP02EDTM":"2022-03-11 03:11:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-11","EOSDY":1096,"LSTALVDT":"2022-03-31","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6427,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92818,"AVALU":"g/L","BASE2":2.81025,"BASE":2.92818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.11794,"PCHG2":4.19676,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-10 09:11:52","ADY":365,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-28","SUBJID":"id-28","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.14445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-10","TRTSDTM":"2019-03-11 09:11:52","TRTEDTM":"2022-03-11 03:11:52","TRT01SDTM":"2019-03-11 09:11:52","TRT01EDTM":"2021-03-10 21:11:52","TRT02SDTM":"2021-03-10 21:11:52","TRT02EDTM":"2022-03-11 03:11:52","AP01SDTM":"2019-03-11 09:11:52","AP01EDTM":"2021-03-10 21:11:52","AP02SDTM":"2021-03-10 21:11:52","AP02EDTM":"2022-03-11 03:11:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-11","EOSDY":1096,"LSTALVDT":"2022-03-31","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4041,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98792,"AVALU":"g/L","BASE2":2.81025,"BASE":2.92818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17767,"PCHG2":6.32223,"CHG":0.05973,"PCHG":2.03986,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-14 09:11:52","ADY":614,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-28","SUBJID":"id-28","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.14445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-10","TRTSDTM":"2019-03-11 09:11:52","TRTEDTM":"2022-03-11 03:11:52","TRT01SDTM":"2019-03-11 09:11:52","TRT01EDTM":"2021-03-10 21:11:52","TRT02SDTM":"2021-03-10 21:11:52","TRT02EDTM":"2022-03-11 03:11:52","AP01SDTM":"2019-03-11 09:11:52","AP01EDTM":"2021-03-10 21:11:52","AP02SDTM":"2021-03-10 21:11:52","AP02EDTM":"2022-03-11 03:11:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-11","EOSDY":1096,"LSTALVDT":"2022-03-31","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7448,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90988,"AVALU":"g/L","BASE2":2.81025,"BASE":2.92818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09963,"PCHG2":3.54541,"CHG":-0.0183,"PCHG":-0.62512,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-09 09:11:52","ADY":760,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-28","SUBJID":"id-28","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.14445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-10","TRTSDTM":"2019-03-11 09:11:52","TRTEDTM":"2022-03-11 03:11:52","TRT01SDTM":"2019-03-11 09:11:52","TRT01EDTM":"2021-03-10 21:11:52","TRT02SDTM":"2021-03-10 21:11:52","TRT02EDTM":"2022-03-11 03:11:52","AP01SDTM":"2019-03-11 09:11:52","AP01EDTM":"2021-03-10 21:11:52","AP02SDTM":"2021-03-10 21:11:52","AP02EDTM":"2022-03-11 03:11:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-11","EOSDY":1096,"LSTALVDT":"2022-03-31","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":411,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.73346,"AVALU":"g/L","BASE2":2.81025,"BASE":2.92818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07679,"PCHG2":-2.73237,"CHG":-0.19473,"PCHG":-6.65005,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-31 09:11:52","ADY":812,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-28","SUBJID":"id-28","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.14445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-10","TRTSDTM":"2019-03-11 09:11:52","TRTEDTM":"2022-03-11 03:11:52","TRT01SDTM":"2019-03-11 09:11:52","TRT01EDTM":"2021-03-10 21:11:52","TRT02SDTM":"2021-03-10 21:11:52","TRT02EDTM":"2022-03-11 03:11:52","AP01SDTM":"2019-03-11 09:11:52","AP01EDTM":"2021-03-10 21:11:52","AP02SDTM":"2021-03-10 21:11:52","AP02EDTM":"2022-03-11 03:11:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-11","EOSDY":1096,"LSTALVDT":"2022-03-31","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":346,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8544,"AVALU":"g/L","BASE2":2.81025,"BASE":2.92818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04415,"PCHG2":1.57121,"CHG":-0.07378,"PCHG":-2.51981,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-13 09:11:52","ADY":1008,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-28","SUBJID":"id-28","SITEID":"CHN-7","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":11.14445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-03-10","TRTSDTM":"2019-03-11 09:11:52","TRTEDTM":"2022-03-11 03:11:52","TRT01SDTM":"2019-03-11 09:11:52","TRT01EDTM":"2021-03-10 21:11:52","TRT02SDTM":"2021-03-10 21:11:52","TRT02EDTM":"2022-03-11 03:11:52","AP01SDTM":"2019-03-11 09:11:52","AP01EDTM":"2021-03-10 21:11:52","AP02SDTM":"2021-03-10 21:11:52","AP02EDTM":"2022-03-11 03:11:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-11","EOSDY":1096,"LSTALVDT":"2022-03-31","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8218,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.68211,"AVALU":"g/L","BASE2":2.81025,"BASE":2.92818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12814,"PCHG2":-4.55964,"CHG":-0.24608,"PCHG":-8.40372,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-19 09:11:52","ADY":1014,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-290","SUBJID":"id-290","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.23873,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 03:12:48","TRTEDTM":"2024-01-15 21:12:48","TRT01SDTM":"2021-01-15 03:12:48","TRT01EDTM":"2023-01-15 15:12:48","TRT02SDTM":"2023-01-15 15:12:48","TRT02EDTM":"2024-01-15 21:12:48","AP01SDTM":"2021-01-15 03:12:48","AP01EDTM":"2023-01-15 15:12:48","AP02SDTM":"2023-01-15 15:12:48","AP02EDTM":"2024-01-15 21:12:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-01-27","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6466,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.54825,"AVALU":"U/L","BASE2":29.54825,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-13 03:12:48","ADY":88,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-290","SUBJID":"id-290","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.23873,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 03:12:48","TRTEDTM":"2024-01-15 21:12:48","TRT01SDTM":"2021-01-15 03:12:48","TRT01EDTM":"2023-01-15 15:12:48","TRT02SDTM":"2023-01-15 15:12:48","TRT02EDTM":"2024-01-15 21:12:48","AP01SDTM":"2021-01-15 03:12:48","AP01EDTM":"2023-01-15 15:12:48","AP02SDTM":"2023-01-15 15:12:48","AP02EDTM":"2024-01-15 21:12:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-01-27","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1590,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.76688,"AVALU":"U/L","BASE2":29.54825,"BASE":24.76688,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-4.78138,"PCHG2":-16.18159,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-13 03:12:48","ADY":210,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-290","SUBJID":"id-290","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.23873,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 03:12:48","TRTEDTM":"2024-01-15 21:12:48","TRT01SDTM":"2021-01-15 03:12:48","TRT01EDTM":"2023-01-15 15:12:48","TRT02SDTM":"2023-01-15 15:12:48","TRT02EDTM":"2024-01-15 21:12:48","AP01SDTM":"2021-01-15 03:12:48","AP01EDTM":"2023-01-15 15:12:48","AP02SDTM":"2023-01-15 15:12:48","AP02EDTM":"2024-01-15 21:12:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-01-27","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3832,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.92146,"AVALU":"U/L","BASE2":29.54825,"BASE":24.76688,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.62679,"PCHG2":-39.3485,"CHG":-6.84542,"PCHG":-27.63941,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-07 03:12:48","ADY":265,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-290","SUBJID":"id-290","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.23873,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 03:12:48","TRTEDTM":"2024-01-15 21:12:48","TRT01SDTM":"2021-01-15 03:12:48","TRT01EDTM":"2023-01-15 15:12:48","TRT02SDTM":"2023-01-15 15:12:48","TRT02EDTM":"2024-01-15 21:12:48","AP01SDTM":"2021-01-15 03:12:48","AP01EDTM":"2023-01-15 15:12:48","AP02SDTM":"2023-01-15 15:12:48","AP02EDTM":"2024-01-15 21:12:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-01-27","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1736,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.50623,"AVALU":"U/L","BASE2":29.54825,"BASE":24.76688,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-29.04202,"PCHG2":-98.28676,"CHG":-24.26064,"PCHG":-97.95601,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-02-17 03:12:48","ADY":398,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-290","SUBJID":"id-290","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.23873,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 03:12:48","TRTEDTM":"2024-01-15 21:12:48","TRT01SDTM":"2021-01-15 03:12:48","TRT01EDTM":"2023-01-15 15:12:48","TRT02SDTM":"2023-01-15 15:12:48","TRT02EDTM":"2024-01-15 21:12:48","AP01SDTM":"2021-01-15 03:12:48","AP01EDTM":"2023-01-15 15:12:48","AP02SDTM":"2023-01-15 15:12:48","AP02EDTM":"2024-01-15 21:12:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-01-27","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1900,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.24237,"AVALU":"U/L","BASE2":29.54825,"BASE":24.76688,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-22.30588,"PCHG2":-75.48969,"CHG":-17.52451,"PCHG":-70.75785,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-29 03:12:48","ADY":560,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-290","SUBJID":"id-290","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.23873,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 03:12:48","TRTEDTM":"2024-01-15 21:12:48","TRT01SDTM":"2021-01-15 03:12:48","TRT01EDTM":"2023-01-15 15:12:48","TRT02SDTM":"2023-01-15 15:12:48","TRT02EDTM":"2024-01-15 21:12:48","AP01SDTM":"2021-01-15 03:12:48","AP01EDTM":"2023-01-15 15:12:48","AP02SDTM":"2023-01-15 15:12:48","AP02EDTM":"2024-01-15 21:12:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-01-27","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2806,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.67092,"AVALU":"U/L","BASE2":29.54825,"BASE":24.76688,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-15.87733,"PCHG2":-53.73358,"CHG":-11.09596,"PCHG":-44.8016,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-11 03:12:48","ADY":604,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-290","SUBJID":"id-290","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.23873,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 03:12:48","TRTEDTM":"2024-01-15 21:12:48","TRT01SDTM":"2021-01-15 03:12:48","TRT01EDTM":"2023-01-15 15:12:48","TRT02SDTM":"2023-01-15 15:12:48","TRT02EDTM":"2024-01-15 21:12:48","AP01SDTM":"2021-01-15 03:12:48","AP01EDTM":"2023-01-15 15:12:48","AP02SDTM":"2023-01-15 15:12:48","AP02EDTM":"2024-01-15 21:12:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-01-27","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3549,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.92706,"AVALU":"U/L","BASE2":29.54825,"BASE":24.76688,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-21.62119,"PCHG2":-73.17249,"CHG":-16.83982,"PCHG":-67.9933,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-08 03:12:48","ADY":843,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-290","SUBJID":"id-290","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.23873,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 03:12:48","TRTEDTM":"2024-01-15 21:12:48","TRT01SDTM":"2021-01-15 03:12:48","TRT01EDTM":"2023-01-15 15:12:48","TRT02SDTM":"2023-01-15 15:12:48","TRT02EDTM":"2024-01-15 21:12:48","AP01SDTM":"2021-01-15 03:12:48","AP01EDTM":"2023-01-15 15:12:48","AP02SDTM":"2023-01-15 15:12:48","AP02EDTM":"2024-01-15 21:12:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-01-27","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3346,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.79419,"AVALU":"mg/L","BASE2":6.79419,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-04-13 03:12:48","ADY":88,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-290","SUBJID":"id-290","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.23873,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 03:12:48","TRTEDTM":"2024-01-15 21:12:48","TRT01SDTM":"2021-01-15 03:12:48","TRT01EDTM":"2023-01-15 15:12:48","TRT02SDTM":"2023-01-15 15:12:48","TRT02EDTM":"2024-01-15 21:12:48","AP01SDTM":"2021-01-15 03:12:48","AP01EDTM":"2023-01-15 15:12:48","AP02SDTM":"2023-01-15 15:12:48","AP02EDTM":"2024-01-15 21:12:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-01-27","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8003,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.04338,"AVALU":"mg/L","BASE2":6.79419,"BASE":9.04338,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.24919,"PCHG2":33.10462,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-13 03:12:48","ADY":210,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-290","SUBJID":"id-290","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.23873,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 03:12:48","TRTEDTM":"2024-01-15 21:12:48","TRT01SDTM":"2021-01-15 03:12:48","TRT01EDTM":"2023-01-15 15:12:48","TRT02SDTM":"2023-01-15 15:12:48","TRT02EDTM":"2024-01-15 21:12:48","AP01SDTM":"2021-01-15 03:12:48","AP01EDTM":"2023-01-15 15:12:48","AP02SDTM":"2023-01-15 15:12:48","AP02EDTM":"2024-01-15 21:12:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-01-27","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3196,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.8049,"AVALU":"mg/L","BASE2":6.79419,"BASE":9.04338,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.01071,"PCHG2":44.313,"CHG":0.76152,"PCHG":8.42073,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-07 03:12:48","ADY":265,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-290","SUBJID":"id-290","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.23873,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 03:12:48","TRTEDTM":"2024-01-15 21:12:48","TRT01SDTM":"2021-01-15 03:12:48","TRT01EDTM":"2023-01-15 15:12:48","TRT02SDTM":"2023-01-15 15:12:48","TRT02EDTM":"2024-01-15 21:12:48","AP01SDTM":"2021-01-15 03:12:48","AP01EDTM":"2023-01-15 15:12:48","AP02SDTM":"2023-01-15 15:12:48","AP02EDTM":"2024-01-15 21:12:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-01-27","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6963,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.80748,"AVALU":"mg/L","BASE2":6.79419,"BASE":9.04338,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.01329,"PCHG2":44.35093,"CHG":0.7641,"PCHG":8.44923,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-17 03:12:48","ADY":398,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-290","SUBJID":"id-290","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.23873,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 03:12:48","TRTEDTM":"2024-01-15 21:12:48","TRT01SDTM":"2021-01-15 03:12:48","TRT01EDTM":"2023-01-15 15:12:48","TRT02SDTM":"2023-01-15 15:12:48","TRT02EDTM":"2024-01-15 21:12:48","AP01SDTM":"2021-01-15 03:12:48","AP01EDTM":"2023-01-15 15:12:48","AP02SDTM":"2023-01-15 15:12:48","AP02EDTM":"2024-01-15 21:12:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-01-27","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4576,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.24867,"AVALU":"mg/L","BASE2":6.79419,"BASE":9.04338,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.45448,"PCHG2":36.12621,"CHG":0.20529,"PCHG":2.27009,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-29 03:12:48","ADY":560,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-290","SUBJID":"id-290","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.23873,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 03:12:48","TRTEDTM":"2024-01-15 21:12:48","TRT01SDTM":"2021-01-15 03:12:48","TRT01EDTM":"2023-01-15 15:12:48","TRT02SDTM":"2023-01-15 15:12:48","TRT02EDTM":"2024-01-15 21:12:48","AP01SDTM":"2021-01-15 03:12:48","AP01EDTM":"2023-01-15 15:12:48","AP02SDTM":"2023-01-15 15:12:48","AP02EDTM":"2024-01-15 21:12:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-01-27","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3262,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.87193,"AVALU":"mg/L","BASE2":6.79419,"BASE":9.04338,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.07774,"PCHG2":30.58108,"CHG":-0.17145,"PCHG":-1.89591,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-11 03:12:48","ADY":604,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-290","SUBJID":"id-290","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.23873,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 03:12:48","TRTEDTM":"2024-01-15 21:12:48","TRT01SDTM":"2021-01-15 03:12:48","TRT01EDTM":"2023-01-15 15:12:48","TRT02SDTM":"2023-01-15 15:12:48","TRT02EDTM":"2024-01-15 21:12:48","AP01SDTM":"2021-01-15 03:12:48","AP01EDTM":"2023-01-15 15:12:48","AP02SDTM":"2023-01-15 15:12:48","AP02EDTM":"2024-01-15 21:12:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-01-27","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3399,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.98654,"AVALU":"mg/L","BASE2":6.79419,"BASE":9.04338,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.19235,"PCHG2":32.26797,"CHG":-0.05684,"PCHG":-0.62856,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-08 03:12:48","ADY":843,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-290","SUBJID":"id-290","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.23873,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 03:12:48","TRTEDTM":"2024-01-15 21:12:48","TRT01SDTM":"2021-01-15 03:12:48","TRT01EDTM":"2023-01-15 15:12:48","TRT02SDTM":"2023-01-15 15:12:48","TRT02EDTM":"2024-01-15 21:12:48","AP01SDTM":"2021-01-15 03:12:48","AP01EDTM":"2023-01-15 15:12:48","AP02SDTM":"2023-01-15 15:12:48","AP02EDTM":"2024-01-15 21:12:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-01-27","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7127,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76314,"AVALU":"g/L","BASE2":2.76314,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-13 03:12:48","ADY":88,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-290","SUBJID":"id-290","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.23873,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 03:12:48","TRTEDTM":"2024-01-15 21:12:48","TRT01SDTM":"2021-01-15 03:12:48","TRT01EDTM":"2023-01-15 15:12:48","TRT02SDTM":"2023-01-15 15:12:48","TRT02EDTM":"2024-01-15 21:12:48","AP01SDTM":"2021-01-15 03:12:48","AP01EDTM":"2023-01-15 15:12:48","AP02SDTM":"2023-01-15 15:12:48","AP02EDTM":"2024-01-15 21:12:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-01-27","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6016,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83808,"AVALU":"g/L","BASE2":2.76314,"BASE":2.83808,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.07495,"PCHG2":2.7124,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-13 03:12:48","ADY":210,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-290","SUBJID":"id-290","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.23873,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 03:12:48","TRTEDTM":"2024-01-15 21:12:48","TRT01SDTM":"2021-01-15 03:12:48","TRT01EDTM":"2023-01-15 15:12:48","TRT02SDTM":"2023-01-15 15:12:48","TRT02EDTM":"2024-01-15 21:12:48","AP01SDTM":"2021-01-15 03:12:48","AP01EDTM":"2023-01-15 15:12:48","AP02SDTM":"2023-01-15 15:12:48","AP02EDTM":"2024-01-15 21:12:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-01-27","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6222,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96083,"AVALU":"g/L","BASE2":2.76314,"BASE":2.83808,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1977,"PCHG2":7.15477,"CHG":0.12275,"PCHG":4.32506,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-07 03:12:48","ADY":265,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-290","SUBJID":"id-290","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.23873,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 03:12:48","TRTEDTM":"2024-01-15 21:12:48","TRT01SDTM":"2021-01-15 03:12:48","TRT01EDTM":"2023-01-15 15:12:48","TRT02SDTM":"2023-01-15 15:12:48","TRT02EDTM":"2024-01-15 21:12:48","AP01SDTM":"2021-01-15 03:12:48","AP01EDTM":"2023-01-15 15:12:48","AP02SDTM":"2023-01-15 15:12:48","AP02EDTM":"2024-01-15 21:12:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-01-27","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3557,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02551,"AVALU":"g/L","BASE2":2.76314,"BASE":2.83808,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.26237,"PCHG2":9.4954,"CHG":0.18742,"PCHG":6.60388,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-02-17 03:12:48","ADY":398,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-290","SUBJID":"id-290","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.23873,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 03:12:48","TRTEDTM":"2024-01-15 21:12:48","TRT01SDTM":"2021-01-15 03:12:48","TRT01EDTM":"2023-01-15 15:12:48","TRT02SDTM":"2023-01-15 15:12:48","TRT02EDTM":"2024-01-15 21:12:48","AP01SDTM":"2021-01-15 03:12:48","AP01EDTM":"2023-01-15 15:12:48","AP02SDTM":"2023-01-15 15:12:48","AP02EDTM":"2024-01-15 21:12:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-01-27","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":69,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77976,"AVALU":"g/L","BASE2":2.76314,"BASE":2.83808,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01663,"PCHG2":0.60173,"CHG":-0.05832,"PCHG":-2.05493,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-29 03:12:48","ADY":560,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-290","SUBJID":"id-290","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.23873,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 03:12:48","TRTEDTM":"2024-01-15 21:12:48","TRT01SDTM":"2021-01-15 03:12:48","TRT01EDTM":"2023-01-15 15:12:48","TRT02SDTM":"2023-01-15 15:12:48","TRT02EDTM":"2024-01-15 21:12:48","AP01SDTM":"2021-01-15 03:12:48","AP01EDTM":"2023-01-15 15:12:48","AP02SDTM":"2023-01-15 15:12:48","AP02EDTM":"2024-01-15 21:12:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-01-27","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":130,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00948,"AVALU":"g/L","BASE2":2.76314,"BASE":2.83808,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.24634,"PCHG2":8.91529,"CHG":0.17139,"PCHG":6.03909,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2022-09-11 03:12:48","ADY":604,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-290","SUBJID":"id-290","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.23873,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-11","TRTSDTM":"2021-01-15 03:12:48","TRTEDTM":"2024-01-15 21:12:48","TRT01SDTM":"2021-01-15 03:12:48","TRT01EDTM":"2023-01-15 15:12:48","TRT02SDTM":"2023-01-15 15:12:48","TRT02EDTM":"2024-01-15 21:12:48","AP01SDTM":"2021-01-15 03:12:48","AP01EDTM":"2023-01-15 15:12:48","AP02SDTM":"2023-01-15 15:12:48","AP02EDTM":"2024-01-15 21:12:48","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-15","EOSDY":1096,"LSTALVDT":"2024-01-27","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":10,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.68421,"AVALU":"g/L","BASE2":2.76314,"BASE":2.83808,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07892,"PCHG2":-2.85628,"CHG":-0.15387,"PCHG":-5.42162,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-08 03:12:48","ADY":843,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-40","SUBJID":"id-40","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.16366,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-27","TRTSDTM":"2020-11-30 05:49:22","TRTEDTM":"2023-11-30 23:49:22","TRT01SDTM":"2020-11-30 05:49:22","TRT01EDTM":"2022-11-30 17:49:22","TRT02SDTM":"2022-11-30 17:49:22","TRT02EDTM":"2023-11-30 23:49:22","AP01SDTM":"2020-11-30 05:49:22","AP01EDTM":"2022-11-30 17:49:22","AP02SDTM":"2022-11-30 17:49:22","AP02EDTM":"2023-11-30 23:49:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-30","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5339,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.04741,"AVALU":"U/L","BASE2":16.04741,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-02 05:49:22","ADY":64,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-40","SUBJID":"id-40","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.16366,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-27","TRTSDTM":"2020-11-30 05:49:22","TRTEDTM":"2023-11-30 23:49:22","TRT01SDTM":"2020-11-30 05:49:22","TRT01EDTM":"2022-11-30 17:49:22","TRT02SDTM":"2022-11-30 17:49:22","TRT02EDTM":"2023-11-30 23:49:22","AP01SDTM":"2020-11-30 05:49:22","AP01EDTM":"2022-11-30 17:49:22","AP02SDTM":"2022-11-30 17:49:22","AP02EDTM":"2023-11-30 23:49:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-30","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1175,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.39559,"AVALU":"U/L","BASE2":16.04741,"BASE":13.39559,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.65182,"PCHG2":-16.52493,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-22 05:49:22","ADY":143,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-40","SUBJID":"id-40","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.16366,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-27","TRTSDTM":"2020-11-30 05:49:22","TRTEDTM":"2023-11-30 23:49:22","TRT01SDTM":"2020-11-30 05:49:22","TRT01EDTM":"2022-11-30 17:49:22","TRT02SDTM":"2022-11-30 17:49:22","TRT02EDTM":"2023-11-30 23:49:22","AP01SDTM":"2020-11-30 05:49:22","AP01EDTM":"2022-11-30 17:49:22","AP02SDTM":"2022-11-30 17:49:22","AP02EDTM":"2023-11-30 23:49:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-30","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3181,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.74296,"AVALU":"U/L","BASE2":16.04741,"BASE":13.39559,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.69554,"PCHG2":35.49198,"CHG":8.34737,"PCHG":62.31431,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-01 05:49:22","ADY":397,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-40","SUBJID":"id-40","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.16366,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-27","TRTSDTM":"2020-11-30 05:49:22","TRTEDTM":"2023-11-30 23:49:22","TRT01SDTM":"2020-11-30 05:49:22","TRT01EDTM":"2022-11-30 17:49:22","TRT02SDTM":"2022-11-30 17:49:22","TRT02EDTM":"2023-11-30 23:49:22","AP01SDTM":"2020-11-30 05:49:22","AP01EDTM":"2022-11-30 17:49:22","AP02SDTM":"2022-11-30 17:49:22","AP02EDTM":"2023-11-30 23:49:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-30","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":777,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.38585,"AVALU":"U/L","BASE2":16.04741,"BASE":13.39559,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.33844,"PCHG2":58.1928,"CHG":11.99026,"PCHG":89.50904,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-22 05:49:22","ADY":418,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-40","SUBJID":"id-40","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.16366,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-27","TRTSDTM":"2020-11-30 05:49:22","TRTEDTM":"2023-11-30 23:49:22","TRT01SDTM":"2020-11-30 05:49:22","TRT01EDTM":"2022-11-30 17:49:22","TRT02SDTM":"2022-11-30 17:49:22","TRT02EDTM":"2023-11-30 23:49:22","AP01SDTM":"2020-11-30 05:49:22","AP01EDTM":"2022-11-30 17:49:22","AP02SDTM":"2022-11-30 17:49:22","AP02EDTM":"2023-11-30 23:49:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-30","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8322,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.95058,"AVALU":"U/L","BASE2":16.04741,"BASE":13.39559,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.09683,"PCHG2":-31.76107,"CHG":-2.44501,"PCHG":-18.25233,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-09 05:49:22","ADY":495,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-40","SUBJID":"id-40","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.16366,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-27","TRTSDTM":"2020-11-30 05:49:22","TRTEDTM":"2023-11-30 23:49:22","TRT01SDTM":"2020-11-30 05:49:22","TRT01EDTM":"2022-11-30 17:49:22","TRT02SDTM":"2022-11-30 17:49:22","TRT02EDTM":"2023-11-30 23:49:22","AP01SDTM":"2020-11-30 05:49:22","AP01EDTM":"2022-11-30 17:49:22","AP02SDTM":"2022-11-30 17:49:22","AP02EDTM":"2023-11-30 23:49:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-30","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7103,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.79723,"AVALU":"U/L","BASE2":16.04741,"BASE":13.39559,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.25018,"PCHG2":-57.64282,"CHG":-6.59836,"PCHG":-49.25769,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2023-01-19 05:49:22","ADY":780,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-40","SUBJID":"id-40","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.16366,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-27","TRTSDTM":"2020-11-30 05:49:22","TRTEDTM":"2023-11-30 23:49:22","TRT01SDTM":"2020-11-30 05:49:22","TRT01EDTM":"2022-11-30 17:49:22","TRT02SDTM":"2022-11-30 17:49:22","TRT02EDTM":"2023-11-30 23:49:22","AP01SDTM":"2020-11-30 05:49:22","AP01EDTM":"2022-11-30 17:49:22","AP02SDTM":"2022-11-30 17:49:22","AP02EDTM":"2023-11-30 23:49:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-30","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6077,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.99185,"AVALU":"U/L","BASE2":16.04741,"BASE":13.39559,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.05556,"PCHG2":-62.66159,"CHG":-7.40374,"PCHG":-55.26999,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2023-05-05 05:49:22","ADY":886,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-40","SUBJID":"id-40","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.16366,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-27","TRTSDTM":"2020-11-30 05:49:22","TRTEDTM":"2023-11-30 23:49:22","TRT01SDTM":"2020-11-30 05:49:22","TRT01EDTM":"2022-11-30 17:49:22","TRT02SDTM":"2022-11-30 17:49:22","TRT02EDTM":"2023-11-30 23:49:22","AP01SDTM":"2020-11-30 05:49:22","AP01EDTM":"2022-11-30 17:49:22","AP02SDTM":"2022-11-30 17:49:22","AP02EDTM":"2023-11-30 23:49:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-30","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1988,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.52646,"AVALU":"mg/L","BASE2":8.52646,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-02 05:49:22","ADY":64,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-40","SUBJID":"id-40","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.16366,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-27","TRTSDTM":"2020-11-30 05:49:22","TRTEDTM":"2023-11-30 23:49:22","TRT01SDTM":"2020-11-30 05:49:22","TRT01EDTM":"2022-11-30 17:49:22","TRT02SDTM":"2022-11-30 17:49:22","TRT02EDTM":"2023-11-30 23:49:22","AP01SDTM":"2020-11-30 05:49:22","AP01EDTM":"2022-11-30 17:49:22","AP02SDTM":"2022-11-30 17:49:22","AP02EDTM":"2023-11-30 23:49:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-30","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5751,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.69247,"AVALU":"mg/L","BASE2":8.52646,"BASE":9.69247,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.166,"PCHG2":13.67511,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-22 05:49:22","ADY":143,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-40","SUBJID":"id-40","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.16366,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-27","TRTSDTM":"2020-11-30 05:49:22","TRTEDTM":"2023-11-30 23:49:22","TRT01SDTM":"2020-11-30 05:49:22","TRT01EDTM":"2022-11-30 17:49:22","TRT02SDTM":"2022-11-30 17:49:22","TRT02EDTM":"2023-11-30 23:49:22","AP01SDTM":"2020-11-30 05:49:22","AP01EDTM":"2022-11-30 17:49:22","AP02SDTM":"2022-11-30 17:49:22","AP02EDTM":"2023-11-30 23:49:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-30","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1449,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.32755,"AVALU":"mg/L","BASE2":8.52646,"BASE":9.69247,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.80109,"PCHG2":9.39533,"CHG":-0.36491,"PCHG":-3.76492,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-01 05:49:22","ADY":397,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-40","SUBJID":"id-40","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.16366,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-27","TRTSDTM":"2020-11-30 05:49:22","TRTEDTM":"2023-11-30 23:49:22","TRT01SDTM":"2020-11-30 05:49:22","TRT01EDTM":"2022-11-30 17:49:22","TRT02SDTM":"2022-11-30 17:49:22","TRT02EDTM":"2023-11-30 23:49:22","AP01SDTM":"2020-11-30 05:49:22","AP01EDTM":"2022-11-30 17:49:22","AP02SDTM":"2022-11-30 17:49:22","AP02EDTM":"2023-11-30 23:49:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-30","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1103,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.69652,"AVALU":"mg/L","BASE2":8.52646,"BASE":9.69247,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.17006,"PCHG2":13.72268,"CHG":0.00406,"PCHG":0.04185,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-22 05:49:22","ADY":418,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-40","SUBJID":"id-40","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.16366,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-27","TRTSDTM":"2020-11-30 05:49:22","TRTEDTM":"2023-11-30 23:49:22","TRT01SDTM":"2020-11-30 05:49:22","TRT01EDTM":"2022-11-30 17:49:22","TRT02SDTM":"2022-11-30 17:49:22","TRT02EDTM":"2023-11-30 23:49:22","AP01SDTM":"2020-11-30 05:49:22","AP01EDTM":"2022-11-30 17:49:22","AP02SDTM":"2022-11-30 17:49:22","AP02EDTM":"2023-11-30 23:49:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-30","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8169,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.24575,"AVALU":"mg/L","BASE2":8.52646,"BASE":9.69247,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.71929,"PCHG2":8.43593,"CHG":-0.44672,"PCHG":-4.60891,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-09 05:49:22","ADY":495,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-40","SUBJID":"id-40","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.16366,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-27","TRTSDTM":"2020-11-30 05:49:22","TRTEDTM":"2023-11-30 23:49:22","TRT01SDTM":"2020-11-30 05:49:22","TRT01EDTM":"2022-11-30 17:49:22","TRT02SDTM":"2022-11-30 17:49:22","TRT02EDTM":"2023-11-30 23:49:22","AP01SDTM":"2020-11-30 05:49:22","AP01EDTM":"2022-11-30 17:49:22","AP02SDTM":"2022-11-30 17:49:22","AP02EDTM":"2023-11-30 23:49:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-30","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2771,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.94856,"AVALU":"mg/L","BASE2":8.52646,"BASE":9.69247,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.42209,"PCHG2":16.67857,"CHG":0.25609,"PCHG":2.64214,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-19 05:49:22","ADY":780,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-40","SUBJID":"id-40","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.16366,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-27","TRTSDTM":"2020-11-30 05:49:22","TRTEDTM":"2023-11-30 23:49:22","TRT01SDTM":"2020-11-30 05:49:22","TRT01EDTM":"2022-11-30 17:49:22","TRT02SDTM":"2022-11-30 17:49:22","TRT02EDTM":"2023-11-30 23:49:22","AP01SDTM":"2020-11-30 05:49:22","AP01EDTM":"2022-11-30 17:49:22","AP02SDTM":"2022-11-30 17:49:22","AP02EDTM":"2023-11-30 23:49:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-30","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6017,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.57571,"AVALU":"mg/L","BASE2":8.52646,"BASE":9.69247,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04925,"PCHG2":0.57757,"CHG":-1.11676,"PCHG":-11.52191,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-05 05:49:22","ADY":886,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-40","SUBJID":"id-40","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.16366,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-27","TRTSDTM":"2020-11-30 05:49:22","TRTEDTM":"2023-11-30 23:49:22","TRT01SDTM":"2020-11-30 05:49:22","TRT01EDTM":"2022-11-30 17:49:22","TRT02SDTM":"2022-11-30 17:49:22","TRT02EDTM":"2023-11-30 23:49:22","AP01SDTM":"2020-11-30 05:49:22","AP01EDTM":"2022-11-30 17:49:22","AP02SDTM":"2022-11-30 17:49:22","AP02EDTM":"2023-11-30 23:49:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-30","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7412,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90401,"AVALU":"g/L","BASE2":2.90401,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-02 05:49:22","ADY":64,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-40","SUBJID":"id-40","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.16366,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-27","TRTSDTM":"2020-11-30 05:49:22","TRTEDTM":"2023-11-30 23:49:22","TRT01SDTM":"2020-11-30 05:49:22","TRT01EDTM":"2022-11-30 17:49:22","TRT02SDTM":"2022-11-30 17:49:22","TRT02EDTM":"2023-11-30 23:49:22","AP01SDTM":"2020-11-30 05:49:22","AP01EDTM":"2022-11-30 17:49:22","AP02SDTM":"2022-11-30 17:49:22","AP02EDTM":"2023-11-30 23:49:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-30","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7213,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86692,"AVALU":"g/L","BASE2":2.90401,"BASE":2.86692,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.03709,"PCHG2":-1.27704,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-22 05:49:22","ADY":143,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-40","SUBJID":"id-40","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.16366,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-27","TRTSDTM":"2020-11-30 05:49:22","TRTEDTM":"2023-11-30 23:49:22","TRT01SDTM":"2020-11-30 05:49:22","TRT01EDTM":"2022-11-30 17:49:22","TRT02SDTM":"2022-11-30 17:49:22","TRT02EDTM":"2023-11-30 23:49:22","AP01SDTM":"2020-11-30 05:49:22","AP01EDTM":"2022-11-30 17:49:22","AP02SDTM":"2022-11-30 17:49:22","AP02EDTM":"2023-11-30 23:49:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-30","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4070,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86335,"AVALU":"g/L","BASE2":2.90401,"BASE":2.86692,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04066,"PCHG2":-1.40019,"CHG":-0.00358,"PCHG":-0.12474,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-01 05:49:22","ADY":397,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-40","SUBJID":"id-40","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.16366,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-27","TRTSDTM":"2020-11-30 05:49:22","TRTEDTM":"2023-11-30 23:49:22","TRT01SDTM":"2020-11-30 05:49:22","TRT01EDTM":"2022-11-30 17:49:22","TRT02SDTM":"2022-11-30 17:49:22","TRT02EDTM":"2023-11-30 23:49:22","AP01SDTM":"2020-11-30 05:49:22","AP01EDTM":"2022-11-30 17:49:22","AP02SDTM":"2022-11-30 17:49:22","AP02EDTM":"2023-11-30 23:49:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-30","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4462,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91431,"AVALU":"g/L","BASE2":2.90401,"BASE":2.86692,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0103,"PCHG2":0.35469,"CHG":0.04739,"PCHG":1.65283,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-22 05:49:22","ADY":418,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-40","SUBJID":"id-40","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.16366,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-27","TRTSDTM":"2020-11-30 05:49:22","TRTEDTM":"2023-11-30 23:49:22","TRT01SDTM":"2020-11-30 05:49:22","TRT01EDTM":"2022-11-30 17:49:22","TRT02SDTM":"2022-11-30 17:49:22","TRT02EDTM":"2023-11-30 23:49:22","AP01SDTM":"2020-11-30 05:49:22","AP01EDTM":"2022-11-30 17:49:22","AP02SDTM":"2022-11-30 17:49:22","AP02EDTM":"2023-11-30 23:49:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-30","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1733,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76636,"AVALU":"g/L","BASE2":2.90401,"BASE":2.86692,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13765,"PCHG2":-4.74011,"CHG":-0.10057,"PCHG":-3.50787,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-09 05:49:22","ADY":495,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-40","SUBJID":"id-40","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.16366,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-27","TRTSDTM":"2020-11-30 05:49:22","TRTEDTM":"2023-11-30 23:49:22","TRT01SDTM":"2020-11-30 05:49:22","TRT01EDTM":"2022-11-30 17:49:22","TRT02SDTM":"2022-11-30 17:49:22","TRT02EDTM":"2023-11-30 23:49:22","AP01SDTM":"2020-11-30 05:49:22","AP01EDTM":"2022-11-30 17:49:22","AP02SDTM":"2022-11-30 17:49:22","AP02EDTM":"2023-11-30 23:49:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-30","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3204,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9504,"AVALU":"g/L","BASE2":2.90401,"BASE":2.86692,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04639,"PCHG2":1.59729,"CHG":0.08347,"PCHG":2.91152,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-19 05:49:22","ADY":780,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-7-id-40","SUBJID":"id-40","SITEID":"CHN-7","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-7","INVNAM":"Dr. CHN-7 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":13.16366,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-27","TRTSDTM":"2020-11-30 05:49:22","TRTEDTM":"2023-11-30 23:49:22","TRT01SDTM":"2020-11-30 05:49:22","TRT01EDTM":"2022-11-30 17:49:22","TRT02SDTM":"2022-11-30 17:49:22","TRT02EDTM":"2023-11-30 23:49:22","AP01SDTM":"2020-11-30 05:49:22","AP01EDTM":"2022-11-30 17:49:22","AP02SDTM":"2022-11-30 17:49:22","AP02EDTM":"2023-11-30 23:49:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-30","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":368,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89285,"AVALU":"g/L","BASE2":2.90401,"BASE":2.86692,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01116,"PCHG2":-0.3844,"CHG":0.02592,"PCHG":0.90418,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-05 05:49:22","ADY":886,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-205","SUBJID":"id-205","SITEID":"CHN-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.15912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-18 16:23:39","TRTEDTM":"2024-01-19 10:23:39","TRT01SDTM":"2021-01-18 16:23:39","TRT01EDTM":"2023-01-19 04:23:39","TRT02SDTM":"2023-01-19 04:23:39","TRT02EDTM":"2024-01-19 10:23:39","AP01SDTM":"2021-01-18 16:23:39","AP01EDTM":"2023-01-19 04:23:39","AP02SDTM":"2023-01-19 04:23:39","AP02EDTM":"2024-01-19 10:23:39","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-19","EOSDY":1096,"LSTALVDT":"2024-02-13","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":677,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.04955,"AVALU":"U/L","BASE2":1.04955,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-02-01 16:23:39","ADY":14,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-205","SUBJID":"id-205","SITEID":"CHN-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.15912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-18 16:23:39","TRTEDTM":"2024-01-19 10:23:39","TRT01SDTM":"2021-01-18 16:23:39","TRT01EDTM":"2023-01-19 04:23:39","TRT02SDTM":"2023-01-19 04:23:39","TRT02EDTM":"2024-01-19 10:23:39","AP01SDTM":"2021-01-18 16:23:39","AP01EDTM":"2023-01-19 04:23:39","AP02SDTM":"2023-01-19 04:23:39","AP02EDTM":"2024-01-19 10:23:39","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-19","EOSDY":1096,"LSTALVDT":"2024-02-13","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1906,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.4165,"AVALU":"U/L","BASE2":1.04955,"BASE":21.4165,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":20.36695,"PCHG2":1940.53282,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-25 16:23:39","ADY":250,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-205","SUBJID":"id-205","SITEID":"CHN-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.15912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-18 16:23:39","TRTEDTM":"2024-01-19 10:23:39","TRT01SDTM":"2021-01-18 16:23:39","TRT01EDTM":"2023-01-19 04:23:39","TRT02SDTM":"2023-01-19 04:23:39","TRT02EDTM":"2024-01-19 10:23:39","AP01SDTM":"2021-01-18 16:23:39","AP01EDTM":"2023-01-19 04:23:39","AP02SDTM":"2023-01-19 04:23:39","AP02EDTM":"2024-01-19 10:23:39","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-19","EOSDY":1096,"LSTALVDT":"2024-02-13","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2525,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.99588,"AVALU":"U/L","BASE2":1.04955,"BASE":21.4165,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":28.94633,"PCHG2":2757.96324,"CHG":8.57938,"PCHG":40.05966,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-28 16:23:39","ADY":344,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-205","SUBJID":"id-205","SITEID":"CHN-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.15912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-18 16:23:39","TRTEDTM":"2024-01-19 10:23:39","TRT01SDTM":"2021-01-18 16:23:39","TRT01EDTM":"2023-01-19 04:23:39","TRT02SDTM":"2023-01-19 04:23:39","TRT02EDTM":"2024-01-19 10:23:39","AP01SDTM":"2021-01-18 16:23:39","AP01EDTM":"2023-01-19 04:23:39","AP02SDTM":"2023-01-19 04:23:39","AP02EDTM":"2024-01-19 10:23:39","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-19","EOSDY":1096,"LSTALVDT":"2024-02-13","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4705,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.47244,"AVALU":"U/L","BASE2":1.04955,"BASE":21.4165,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.42289,"PCHG2":1088.35572,"CHG":-8.94406,"PCHG":-41.76248,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-26 16:23:39","ADY":373,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-205","SUBJID":"id-205","SITEID":"CHN-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.15912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-18 16:23:39","TRTEDTM":"2024-01-19 10:23:39","TRT01SDTM":"2021-01-18 16:23:39","TRT01EDTM":"2023-01-19 04:23:39","TRT02SDTM":"2023-01-19 04:23:39","TRT02EDTM":"2024-01-19 10:23:39","AP01SDTM":"2021-01-18 16:23:39","AP01EDTM":"2023-01-19 04:23:39","AP02SDTM":"2023-01-19 04:23:39","AP02EDTM":"2024-01-19 10:23:39","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-19","EOSDY":1096,"LSTALVDT":"2024-02-13","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1262,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.28662,"AVALU":"U/L","BASE2":1.04955,"BASE":21.4165,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":28.23706,"PCHG2":2690.38554,"CHG":7.87011,"PCHG":36.74789,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-10 16:23:39","ADY":477,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-205","SUBJID":"id-205","SITEID":"CHN-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.15912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-18 16:23:39","TRTEDTM":"2024-01-19 10:23:39","TRT01SDTM":"2021-01-18 16:23:39","TRT01EDTM":"2023-01-19 04:23:39","TRT02SDTM":"2023-01-19 04:23:39","TRT02EDTM":"2024-01-19 10:23:39","AP01SDTM":"2021-01-18 16:23:39","AP01EDTM":"2023-01-19 04:23:39","AP02SDTM":"2023-01-19 04:23:39","AP02EDTM":"2024-01-19 10:23:39","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-19","EOSDY":1096,"LSTALVDT":"2024-02-13","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3485,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.15003,"AVALU":"U/L","BASE2":1.04955,"BASE":21.4165,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":31.10047,"PCHG2":2963.20719,"CHG":10.73352,"PCHG":50.11801,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-13 16:23:39","ADY":603,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-205","SUBJID":"id-205","SITEID":"CHN-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.15912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-18 16:23:39","TRTEDTM":"2024-01-19 10:23:39","TRT01SDTM":"2021-01-18 16:23:39","TRT01EDTM":"2023-01-19 04:23:39","TRT02SDTM":"2023-01-19 04:23:39","TRT02EDTM":"2024-01-19 10:23:39","AP01SDTM":"2021-01-18 16:23:39","AP01EDTM":"2023-01-19 04:23:39","AP02SDTM":"2023-01-19 04:23:39","AP02EDTM":"2024-01-19 10:23:39","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-19","EOSDY":1096,"LSTALVDT":"2024-02-13","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2776,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.43348,"AVALU":"U/L","BASE2":1.04955,"BASE":21.4165,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.38392,"PCHG2":1084.64352,"CHG":-8.98302,"PCHG":-41.9444,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-27 16:23:39","ADY":617,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-205","SUBJID":"id-205","SITEID":"CHN-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.15912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-18 16:23:39","TRTEDTM":"2024-01-19 10:23:39","TRT01SDTM":"2021-01-18 16:23:39","TRT01EDTM":"2023-01-19 04:23:39","TRT02SDTM":"2023-01-19 04:23:39","TRT02EDTM":"2024-01-19 10:23:39","AP01SDTM":"2021-01-18 16:23:39","AP01EDTM":"2023-01-19 04:23:39","AP02SDTM":"2023-01-19 04:23:39","AP02EDTM":"2024-01-19 10:23:39","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-19","EOSDY":1096,"LSTALVDT":"2024-02-13","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5985,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.08502,"AVALU":"mg/L","BASE2":9.08502,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-01 16:23:39","ADY":14,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-205","SUBJID":"id-205","SITEID":"CHN-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.15912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-18 16:23:39","TRTEDTM":"2024-01-19 10:23:39","TRT01SDTM":"2021-01-18 16:23:39","TRT01EDTM":"2023-01-19 04:23:39","TRT02SDTM":"2023-01-19 04:23:39","TRT02EDTM":"2024-01-19 10:23:39","AP01SDTM":"2021-01-18 16:23:39","AP01EDTM":"2023-01-19 04:23:39","AP02SDTM":"2023-01-19 04:23:39","AP02EDTM":"2024-01-19 10:23:39","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-19","EOSDY":1096,"LSTALVDT":"2024-02-13","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3356,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.95592,"AVALU":"mg/L","BASE2":9.08502,"BASE":8.95592,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.1291,"PCHG2":-1.42101,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-25 16:23:39","ADY":250,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-205","SUBJID":"id-205","SITEID":"CHN-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.15912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-18 16:23:39","TRTEDTM":"2024-01-19 10:23:39","TRT01SDTM":"2021-01-18 16:23:39","TRT01EDTM":"2023-01-19 04:23:39","TRT02SDTM":"2023-01-19 04:23:39","TRT02EDTM":"2024-01-19 10:23:39","AP01SDTM":"2021-01-18 16:23:39","AP01EDTM":"2023-01-19 04:23:39","AP02SDTM":"2023-01-19 04:23:39","AP02EDTM":"2024-01-19 10:23:39","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-19","EOSDY":1096,"LSTALVDT":"2024-02-13","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2662,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.53108,"AVALU":"mg/L","BASE2":9.08502,"BASE":8.95592,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.55394,"PCHG2":-28.11155,"CHG":-2.42484,"PCHG":-27.07528,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-12-28 16:23:39","ADY":344,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-205","SUBJID":"id-205","SITEID":"CHN-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.15912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-18 16:23:39","TRTEDTM":"2024-01-19 10:23:39","TRT01SDTM":"2021-01-18 16:23:39","TRT01EDTM":"2023-01-19 04:23:39","TRT02SDTM":"2023-01-19 04:23:39","TRT02EDTM":"2024-01-19 10:23:39","AP01SDTM":"2021-01-18 16:23:39","AP01EDTM":"2023-01-19 04:23:39","AP02SDTM":"2023-01-19 04:23:39","AP02EDTM":"2024-01-19 10:23:39","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-19","EOSDY":1096,"LSTALVDT":"2024-02-13","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7132,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.05836,"AVALU":"mg/L","BASE2":9.08502,"BASE":8.95592,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.97334,"PCHG2":10.71364,"CHG":1.10243,"PCHG":12.30956,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-01-26 16:23:39","ADY":373,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-205","SUBJID":"id-205","SITEID":"CHN-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.15912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-18 16:23:39","TRTEDTM":"2024-01-19 10:23:39","TRT01SDTM":"2021-01-18 16:23:39","TRT01EDTM":"2023-01-19 04:23:39","TRT02SDTM":"2023-01-19 04:23:39","TRT02EDTM":"2024-01-19 10:23:39","AP01SDTM":"2021-01-18 16:23:39","AP01EDTM":"2023-01-19 04:23:39","AP02SDTM":"2023-01-19 04:23:39","AP02EDTM":"2024-01-19 10:23:39","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-19","EOSDY":1096,"LSTALVDT":"2024-02-13","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6904,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.72869,"AVALU":"mg/L","BASE2":9.08502,"BASE":8.95592,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.35633,"PCHG2":-3.92218,"CHG":-0.22723,"PCHG":-2.53723,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-10 16:23:39","ADY":477,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-205","SUBJID":"id-205","SITEID":"CHN-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.15912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-18 16:23:39","TRTEDTM":"2024-01-19 10:23:39","TRT01SDTM":"2021-01-18 16:23:39","TRT01EDTM":"2023-01-19 04:23:39","TRT02SDTM":"2023-01-19 04:23:39","TRT02EDTM":"2024-01-19 10:23:39","AP01SDTM":"2021-01-18 16:23:39","AP01EDTM":"2023-01-19 04:23:39","AP02SDTM":"2023-01-19 04:23:39","AP02EDTM":"2024-01-19 10:23:39","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-19","EOSDY":1096,"LSTALVDT":"2024-02-13","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7301,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.52196,"AVALU":"mg/L","BASE2":9.08502,"BASE":8.95592,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.43694,"PCHG2":4.80942,"CHG":0.56604,"PCHG":6.32023,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-13 16:23:39","ADY":603,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-205","SUBJID":"id-205","SITEID":"CHN-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.15912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-18 16:23:39","TRTEDTM":"2024-01-19 10:23:39","TRT01SDTM":"2021-01-18 16:23:39","TRT01EDTM":"2023-01-19 04:23:39","TRT02SDTM":"2023-01-19 04:23:39","TRT02EDTM":"2024-01-19 10:23:39","AP01SDTM":"2021-01-18 16:23:39","AP01EDTM":"2023-01-19 04:23:39","AP02SDTM":"2023-01-19 04:23:39","AP02EDTM":"2024-01-19 10:23:39","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-19","EOSDY":1096,"LSTALVDT":"2024-02-13","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5410,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.23634,"AVALU":"mg/L","BASE2":9.08502,"BASE":8.95592,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.84868,"PCHG2":-9.34154,"CHG":-0.71958,"PCHG":-8.03471,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-27 16:23:39","ADY":617,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-205","SUBJID":"id-205","SITEID":"CHN-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.15912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-18 16:23:39","TRTEDTM":"2024-01-19 10:23:39","TRT01SDTM":"2021-01-18 16:23:39","TRT01EDTM":"2023-01-19 04:23:39","TRT02SDTM":"2023-01-19 04:23:39","TRT02EDTM":"2024-01-19 10:23:39","AP01SDTM":"2021-01-18 16:23:39","AP01EDTM":"2023-01-19 04:23:39","AP02SDTM":"2023-01-19 04:23:39","AP02EDTM":"2024-01-19 10:23:39","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-19","EOSDY":1096,"LSTALVDT":"2024-02-13","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1149,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85995,"AVALU":"g/L","BASE2":2.85995,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-01 16:23:39","ADY":14,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-205","SUBJID":"id-205","SITEID":"CHN-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.15912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-18 16:23:39","TRTEDTM":"2024-01-19 10:23:39","TRT01SDTM":"2021-01-18 16:23:39","TRT01EDTM":"2023-01-19 04:23:39","TRT02SDTM":"2023-01-19 04:23:39","TRT02EDTM":"2024-01-19 10:23:39","AP01SDTM":"2021-01-18 16:23:39","AP01EDTM":"2023-01-19 04:23:39","AP02SDTM":"2023-01-19 04:23:39","AP02EDTM":"2024-01-19 10:23:39","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-19","EOSDY":1096,"LSTALVDT":"2024-02-13","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2469,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87688,"AVALU":"g/L","BASE2":2.85995,"BASE":2.87688,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.01693,"PCHG2":0.59183,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-25 16:23:39","ADY":250,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-205","SUBJID":"id-205","SITEID":"CHN-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.15912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-18 16:23:39","TRTEDTM":"2024-01-19 10:23:39","TRT01SDTM":"2021-01-18 16:23:39","TRT01EDTM":"2023-01-19 04:23:39","TRT02SDTM":"2023-01-19 04:23:39","TRT02EDTM":"2024-01-19 10:23:39","AP01SDTM":"2021-01-18 16:23:39","AP01EDTM":"2023-01-19 04:23:39","AP02SDTM":"2023-01-19 04:23:39","AP02EDTM":"2024-01-19 10:23:39","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-19","EOSDY":1096,"LSTALVDT":"2024-02-13","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":33,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77322,"AVALU":"g/L","BASE2":2.85995,"BASE":2.87688,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08673,"PCHG2":-3.03265,"CHG":-0.10366,"PCHG":-3.60316,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-28 16:23:39","ADY":344,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-205","SUBJID":"id-205","SITEID":"CHN-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.15912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-18 16:23:39","TRTEDTM":"2024-01-19 10:23:39","TRT01SDTM":"2021-01-18 16:23:39","TRT01EDTM":"2023-01-19 04:23:39","TRT02SDTM":"2023-01-19 04:23:39","TRT02EDTM":"2024-01-19 10:23:39","AP01SDTM":"2021-01-18 16:23:39","AP01EDTM":"2023-01-19 04:23:39","AP02SDTM":"2023-01-19 04:23:39","AP02EDTM":"2024-01-19 10:23:39","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-19","EOSDY":1096,"LSTALVDT":"2024-02-13","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3031,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93163,"AVALU":"g/L","BASE2":2.85995,"BASE":2.87688,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07168,"PCHG2":2.50621,"CHG":0.05475,"PCHG":1.90312,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-26 16:23:39","ADY":373,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-205","SUBJID":"id-205","SITEID":"CHN-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.15912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-18 16:23:39","TRTEDTM":"2024-01-19 10:23:39","TRT01SDTM":"2021-01-18 16:23:39","TRT01EDTM":"2023-01-19 04:23:39","TRT02SDTM":"2023-01-19 04:23:39","TRT02EDTM":"2024-01-19 10:23:39","AP01SDTM":"2021-01-18 16:23:39","AP01EDTM":"2023-01-19 04:23:39","AP02SDTM":"2023-01-19 04:23:39","AP02EDTM":"2024-01-19 10:23:39","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-19","EOSDY":1096,"LSTALVDT":"2024-02-13","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":488,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.08142,"AVALU":"g/L","BASE2":2.85995,"BASE":2.87688,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.22147,"PCHG2":7.74372,"CHG":0.20454,"PCHG":7.10981,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-05-10 16:23:39","ADY":477,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-205","SUBJID":"id-205","SITEID":"CHN-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.15912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-18 16:23:39","TRTEDTM":"2024-01-19 10:23:39","TRT01SDTM":"2021-01-18 16:23:39","TRT01EDTM":"2023-01-19 04:23:39","TRT02SDTM":"2023-01-19 04:23:39","TRT02EDTM":"2024-01-19 10:23:39","AP01SDTM":"2021-01-18 16:23:39","AP01EDTM":"2023-01-19 04:23:39","AP02SDTM":"2023-01-19 04:23:39","AP02EDTM":"2024-01-19 10:23:39","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-19","EOSDY":1096,"LSTALVDT":"2024-02-13","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3137,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88678,"AVALU":"g/L","BASE2":2.85995,"BASE":2.87688,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02683,"PCHG2":0.93813,"CHG":0.0099,"PCHG":0.34426,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-13 16:23:39","ADY":603,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-205","SUBJID":"id-205","SITEID":"CHN-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.15912,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-14","TRTSDTM":"2021-01-18 16:23:39","TRTEDTM":"2024-01-19 10:23:39","TRT01SDTM":"2021-01-18 16:23:39","TRT01EDTM":"2023-01-19 04:23:39","TRT02SDTM":"2023-01-19 04:23:39","TRT02EDTM":"2024-01-19 10:23:39","AP01SDTM":"2021-01-18 16:23:39","AP01EDTM":"2023-01-19 04:23:39","AP02SDTM":"2023-01-19 04:23:39","AP02EDTM":"2024-01-19 10:23:39","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-19","EOSDY":1096,"LSTALVDT":"2024-02-13","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":186,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97026,"AVALU":"g/L","BASE2":2.85995,"BASE":2.87688,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1103,"PCHG2":3.85682,"CHG":0.09338,"PCHG":3.24578,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-27 16:23:39","ADY":617,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-299","SUBJID":"id-299","SITEID":"CHN-8","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.15502,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-09","TRTSDTM":"2019-11-09 02:49:13","TRT01SDTM":"2019-11-09 02:49:13","AP01SDTM":"2019-11-09 02:49:13","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":882,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.47905,"AVALU":"U/L","BASE2":11.47905,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-21 02:49:13","ADY":133,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-299","SUBJID":"id-299","SITEID":"CHN-8","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.15502,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-09","TRTSDTM":"2019-11-09 02:49:13","TRT01SDTM":"2019-11-09 02:49:13","AP01SDTM":"2019-11-09 02:49:13","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1239,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.97444,"AVALU":"U/L","BASE2":11.47905,"BASE":17.97444,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":6.49539,"PCHG2":56.58472,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-19 02:49:13","ADY":162,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-299","SUBJID":"id-299","SITEID":"CHN-8","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.15502,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-09","TRTSDTM":"2019-11-09 02:49:13","TRT01SDTM":"2019-11-09 02:49:13","AP01SDTM":"2019-11-09 02:49:13","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6912,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.44661,"AVALU":"U/L","BASE2":11.47905,"BASE":17.97444,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.03244,"PCHG2":-35.12871,"CHG":-10.52783,"PCHG":-58.57112,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-14 02:49:13","ADY":187,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-299","SUBJID":"id-299","SITEID":"CHN-8","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.15502,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-09","TRTSDTM":"2019-11-09 02:49:13","TRT01SDTM":"2019-11-09 02:49:13","AP01SDTM":"2019-11-09 02:49:13","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6430,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":38.26695,"AVALU":"U/L","BASE2":11.47905,"BASE":17.97444,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":26.7879,"PCHG2":233.36333,"CHG":20.29251,"PCHG":112.89646,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-18 02:49:13","ADY":191,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-299","SUBJID":"id-299","SITEID":"CHN-8","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.15502,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-09","TRTSDTM":"2019-11-09 02:49:13","TRT01SDTM":"2019-11-09 02:49:13","AP01SDTM":"2019-11-09 02:49:13","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3326,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.58334,"AVALU":"U/L","BASE2":11.47905,"BASE":17.97444,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.10429,"PCHG2":18.33153,"CHG":-4.3911,"PCHG":-24.42971,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-22 02:49:13","ADY":591,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-299","SUBJID":"id-299","SITEID":"CHN-8","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.15502,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-09","TRTSDTM":"2019-11-09 02:49:13","TRT01SDTM":"2019-11-09 02:49:13","AP01SDTM":"2019-11-09 02:49:13","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3109,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.31568,"AVALU":"U/L","BASE2":11.47905,"BASE":17.97444,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.16337,"PCHG2":-53.69234,"CHG":-12.65876,"PCHG":-70.42645,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-09-12 02:49:13","ADY":673,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-299","SUBJID":"id-299","SITEID":"CHN-8","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.15502,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-09","TRTSDTM":"2019-11-09 02:49:13","TRT01SDTM":"2019-11-09 02:49:13","AP01SDTM":"2019-11-09 02:49:13","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2515,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":38.76765,"AVALU":"U/L","BASE2":11.47905,"BASE":17.97444,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":27.2886,"PCHG2":237.72523,"CHG":20.79321,"PCHG":115.68211,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-23 02:49:13","ADY":714,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-299","SUBJID":"id-299","SITEID":"CHN-8","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.15502,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-09","TRTSDTM":"2019-11-09 02:49:13","TRT01SDTM":"2019-11-09 02:49:13","AP01SDTM":"2019-11-09 02:49:13","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2218,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.00103,"AVALU":"mg/L","BASE2":9.00103,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-03-21 02:49:13","ADY":133,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-299","SUBJID":"id-299","SITEID":"CHN-8","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.15502,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-09","TRTSDTM":"2019-11-09 02:49:13","TRT01SDTM":"2019-11-09 02:49:13","AP01SDTM":"2019-11-09 02:49:13","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3987,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.57639,"AVALU":"mg/L","BASE2":9.00103,"BASE":7.57639,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.42464,"PCHG2":-15.82749,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2020-04-19 02:49:13","ADY":162,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-299","SUBJID":"id-299","SITEID":"CHN-8","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.15502,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-09","TRTSDTM":"2019-11-09 02:49:13","TRT01SDTM":"2019-11-09 02:49:13","AP01SDTM":"2019-11-09 02:49:13","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5764,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.07651,"AVALU":"mg/L","BASE2":9.00103,"BASE":7.57639,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.07548,"PCHG2":11.94841,"CHG":2.50012,"PCHG":32.99877,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"1","BTOXGR":"-1","ADTM":"2020-05-14 02:49:13","ADY":187,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-299","SUBJID":"id-299","SITEID":"CHN-8","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.15502,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-09","TRTSDTM":"2019-11-09 02:49:13","TRT01SDTM":"2019-11-09 02:49:13","AP01SDTM":"2019-11-09 02:49:13","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6711,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.9342,"AVALU":"mg/L","BASE2":9.00103,"BASE":7.57639,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.06683,"PCHG2":-11.85232,"CHG":0.35781,"PCHG":4.72264,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-4","BTOXGR":"-1","ADTM":"2020-05-18 02:49:13","ADY":191,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-299","SUBJID":"id-299","SITEID":"CHN-8","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.15502,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-09","TRTSDTM":"2019-11-09 02:49:13","TRT01SDTM":"2019-11-09 02:49:13","AP01SDTM":"2019-11-09 02:49:13","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2191,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.02046,"AVALU":"mg/L","BASE2":9.00103,"BASE":7.57639,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.01943,"PCHG2":22.43558,"CHG":3.44407,"PCHG":45.45791,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"3","BTOXGR":"-1","ADTM":"2021-06-22 02:49:13","ADY":591,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-299","SUBJID":"id-299","SITEID":"CHN-8","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.15502,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-09","TRTSDTM":"2019-11-09 02:49:13","TRT01SDTM":"2019-11-09 02:49:13","AP01SDTM":"2019-11-09 02:49:13","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5570,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.81904,"AVALU":"mg/L","BASE2":9.00103,"BASE":7.57639,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18199,"PCHG2":-2.02184,"CHG":1.24265,"PCHG":16.4016,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-09-12 02:49:13","ADY":673,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-299","SUBJID":"id-299","SITEID":"CHN-8","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.15502,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-09","TRTSDTM":"2019-11-09 02:49:13","TRT01SDTM":"2019-11-09 02:49:13","AP01SDTM":"2019-11-09 02:49:13","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4685,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.67204,"AVALU":"mg/L","BASE2":9.00103,"BASE":7.57639,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.67101,"PCHG2":7.45485,"CHG":2.09565,"PCHG":27.66026,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-10-23 02:49:13","ADY":714,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-299","SUBJID":"id-299","SITEID":"CHN-8","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.15502,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-09","TRTSDTM":"2019-11-09 02:49:13","TRT01SDTM":"2019-11-09 02:49:13","AP01SDTM":"2019-11-09 02:49:13","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5452,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91024,"AVALU":"g/L","BASE2":2.91024,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-21 02:49:13","ADY":133,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-299","SUBJID":"id-299","SITEID":"CHN-8","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.15502,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-09","TRTSDTM":"2019-11-09 02:49:13","TRT01SDTM":"2019-11-09 02:49:13","AP01SDTM":"2019-11-09 02:49:13","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":142,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92224,"AVALU":"g/L","BASE2":2.91024,"BASE":2.92224,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.012,"PCHG2":0.41224,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-19 02:49:13","ADY":162,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-299","SUBJID":"id-299","SITEID":"CHN-8","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.15502,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-09","TRTSDTM":"2019-11-09 02:49:13","TRT01SDTM":"2019-11-09 02:49:13","AP01SDTM":"2019-11-09 02:49:13","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7844,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01342,"AVALU":"g/L","BASE2":2.91024,"BASE":2.92224,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10318,"PCHG2":3.54526,"CHG":0.09118,"PCHG":3.12016,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-05-14 02:49:13","ADY":187,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-299","SUBJID":"id-299","SITEID":"CHN-8","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.15502,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-09","TRTSDTM":"2019-11-09 02:49:13","TRT01SDTM":"2019-11-09 02:49:13","AP01SDTM":"2019-11-09 02:49:13","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7027,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.11418,"AVALU":"g/L","BASE2":2.91024,"BASE":2.92224,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.20394,"PCHG2":7.00755,"CHG":0.19194,"PCHG":6.56824,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-05-18 02:49:13","ADY":191,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-299","SUBJID":"id-299","SITEID":"CHN-8","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.15502,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-09","TRTSDTM":"2019-11-09 02:49:13","TRT01SDTM":"2019-11-09 02:49:13","AP01SDTM":"2019-11-09 02:49:13","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5430,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8862,"AVALU":"g/L","BASE2":2.91024,"BASE":2.92224,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02405,"PCHG2":-0.82627,"CHG":-0.03604,"PCHG":-1.23342,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-22 02:49:13","ADY":591,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-299","SUBJID":"id-299","SITEID":"CHN-8","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.15502,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-09","TRTSDTM":"2019-11-09 02:49:13","TRT01SDTM":"2019-11-09 02:49:13","AP01SDTM":"2019-11-09 02:49:13","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1320,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8293,"AVALU":"g/L","BASE2":2.91024,"BASE":2.92224,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08094,"PCHG2":-2.78125,"CHG":-0.09294,"PCHG":-3.18038,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-12 02:49:13","ADY":673,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-8-id-299","SUBJID":"id-299","SITEID":"CHN-8","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-8","INVNAM":"Dr. CHN-8 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":3.15502,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-09","TRTSDTM":"2019-11-09 02:49:13","TRT01SDTM":"2019-11-09 02:49:13","AP01SDTM":"2019-11-09 02:49:13","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3411,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8412,"AVALU":"g/L","BASE2":2.91024,"BASE":2.92224,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06905,"PCHG2":-2.37256,"CHG":-0.08104,"PCHG":-2.77336,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-23 02:49:13","ADY":714,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-11","SUBJID":"id-11","SITEID":"CHN-9","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.26792,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2021-01-26","TRTSDTM":"2021-01-27 02:18:01","TRTEDTM":"2022-02-18 10:34:01","TRT01SDTM":"2021-01-27 02:18:01","TRT01EDTM":"2021-02-18 04:34:01","TRT02SDTM":"2021-02-18 04:34:01","TRT02EDTM":"2022-02-18 10:34:01","AP01SDTM":"2021-01-27 02:18:01","AP01EDTM":"2021-02-18 04:34:01","AP02SDTM":"2021-02-18 04:34:01","AP02EDTM":"2022-02-18 10:34:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":388,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":398,"ADTHAUT":"No","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1931,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.89841,"AVALU":"U/L","BASE2":16.89841,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-03-05 02:18:01","ADY":37,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-11","SUBJID":"id-11","SITEID":"CHN-9","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.26792,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2021-01-26","TRTSDTM":"2021-01-27 02:18:01","TRTEDTM":"2022-02-18 10:34:01","TRT01SDTM":"2021-01-27 02:18:01","TRT01EDTM":"2021-02-18 04:34:01","TRT02SDTM":"2021-02-18 04:34:01","TRT02EDTM":"2022-02-18 10:34:01","AP01SDTM":"2021-01-27 02:18:01","AP01EDTM":"2021-02-18 04:34:01","AP02SDTM":"2021-02-18 04:34:01","AP02EDTM":"2022-02-18 10:34:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":388,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":398,"ADTHAUT":"No","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6517,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.11422,"AVALU":"U/L","BASE2":16.89841,"BASE":3.11422,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-13.78419,"PCHG2":-81.57092,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2021-04-19 02:18:01","ADY":82,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-11","SUBJID":"id-11","SITEID":"CHN-9","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.26792,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2021-01-26","TRTSDTM":"2021-01-27 02:18:01","TRTEDTM":"2022-02-18 10:34:01","TRT01SDTM":"2021-01-27 02:18:01","TRT01EDTM":"2021-02-18 04:34:01","TRT02SDTM":"2021-02-18 04:34:01","TRT02EDTM":"2022-02-18 10:34:01","AP01SDTM":"2021-01-27 02:18:01","AP01EDTM":"2021-02-18 04:34:01","AP02SDTM":"2021-02-18 04:34:01","AP02EDTM":"2022-02-18 10:34:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":388,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":398,"ADTHAUT":"No","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2157,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.92323,"AVALU":"U/L","BASE2":16.89841,"BASE":3.11422,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.02482,"PCHG2":11.98231,"CHG":15.80901,"PCHG":507.63933,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-05-29 02:18:01","ADY":122,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-11","SUBJID":"id-11","SITEID":"CHN-9","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.26792,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2021-01-26","TRTSDTM":"2021-01-27 02:18:01","TRTEDTM":"2022-02-18 10:34:01","TRT01SDTM":"2021-01-27 02:18:01","TRT01EDTM":"2021-02-18 04:34:01","TRT02SDTM":"2021-02-18 04:34:01","TRT02EDTM":"2022-02-18 10:34:01","AP01SDTM":"2021-01-27 02:18:01","AP01EDTM":"2021-02-18 04:34:01","AP02SDTM":"2021-02-18 04:34:01","AP02EDTM":"2022-02-18 10:34:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":388,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":398,"ADTHAUT":"No","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":843,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.05148,"AVALU":"U/L","BASE2":16.89841,"BASE":3.11422,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.15307,"PCHG2":66.0007,"CHG":24.93726,"PCHG":800.75437,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-07-14 02:18:01","ADY":168,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-11","SUBJID":"id-11","SITEID":"CHN-9","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.26792,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2021-01-26","TRTSDTM":"2021-01-27 02:18:01","TRTEDTM":"2022-02-18 10:34:01","TRT01SDTM":"2021-01-27 02:18:01","TRT01EDTM":"2021-02-18 04:34:01","TRT02SDTM":"2021-02-18 04:34:01","TRT02EDTM":"2022-02-18 10:34:01","AP01SDTM":"2021-01-27 02:18:01","AP01EDTM":"2021-02-18 04:34:01","AP02SDTM":"2021-02-18 04:34:01","AP02EDTM":"2022-02-18 10:34:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":388,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":398,"ADTHAUT":"No","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1110,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.13183,"AVALU":"U/L","BASE2":16.89841,"BASE":3.11422,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.23342,"PCHG2":1.3813,"CHG":14.01761,"PCHG":450.11605,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-10-30 02:18:01","ADY":276,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-11","SUBJID":"id-11","SITEID":"CHN-9","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.26792,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2021-01-26","TRTSDTM":"2021-01-27 02:18:01","TRTEDTM":"2022-02-18 10:34:01","TRT01SDTM":"2021-01-27 02:18:01","TRT01EDTM":"2021-02-18 04:34:01","TRT02SDTM":"2021-02-18 04:34:01","TRT02EDTM":"2022-02-18 10:34:01","AP01SDTM":"2021-01-27 02:18:01","AP01EDTM":"2021-02-18 04:34:01","AP02SDTM":"2021-02-18 04:34:01","AP02EDTM":"2022-02-18 10:34:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":388,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":398,"ADTHAUT":"No","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5816,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.9111,"AVALU":"U/L","BASE2":16.89841,"BASE":3.11422,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.01269,"PCHG2":29.66367,"CHG":18.79688,"PCHG":603.58206,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-12-16 02:18:01","ADY":323,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-11","SUBJID":"id-11","SITEID":"CHN-9","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.26792,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2021-01-26","TRTSDTM":"2021-01-27 02:18:01","TRTEDTM":"2022-02-18 10:34:01","TRT01SDTM":"2021-01-27 02:18:01","TRT01EDTM":"2021-02-18 04:34:01","TRT02SDTM":"2021-02-18 04:34:01","TRT02EDTM":"2022-02-18 10:34:01","AP01SDTM":"2021-01-27 02:18:01","AP01EDTM":"2021-02-18 04:34:01","AP02SDTM":"2021-02-18 04:34:01","AP02EDTM":"2022-02-18 10:34:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":388,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":398,"ADTHAUT":"No","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2303,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.72206,"AVALU":"U/L","BASE2":16.89841,"BASE":3.11422,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.82364,"PCHG2":10.7918,"CHG":15.60783,"PCHG":501.17937,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-02-07 02:18:01","ADY":376,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-11","SUBJID":"id-11","SITEID":"CHN-9","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.26792,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2021-01-26","TRTSDTM":"2021-01-27 02:18:01","TRTEDTM":"2022-02-18 10:34:01","TRT01SDTM":"2021-01-27 02:18:01","TRT01EDTM":"2021-02-18 04:34:01","TRT02SDTM":"2021-02-18 04:34:01","TRT02EDTM":"2022-02-18 10:34:01","AP01SDTM":"2021-01-27 02:18:01","AP01EDTM":"2021-02-18 04:34:01","AP02SDTM":"2021-02-18 04:34:01","AP02EDTM":"2022-02-18 10:34:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":388,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":398,"ADTHAUT":"No","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4417,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.07315,"AVALU":"mg/L","BASE2":8.07315,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-05 02:18:01","ADY":37,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-11","SUBJID":"id-11","SITEID":"CHN-9","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.26792,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2021-01-26","TRTSDTM":"2021-01-27 02:18:01","TRTEDTM":"2022-02-18 10:34:01","TRT01SDTM":"2021-01-27 02:18:01","TRT01EDTM":"2021-02-18 04:34:01","TRT02SDTM":"2021-02-18 04:34:01","TRT02EDTM":"2022-02-18 10:34:01","AP01SDTM":"2021-01-27 02:18:01","AP01EDTM":"2021-02-18 04:34:01","AP02SDTM":"2021-02-18 04:34:01","AP02EDTM":"2022-02-18 10:34:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":388,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":398,"ADTHAUT":"No","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7824,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.95469,"AVALU":"mg/L","BASE2":8.07315,"BASE":8.95469,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.88154,"PCHG2":10.91934,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-19 02:18:01","ADY":82,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-11","SUBJID":"id-11","SITEID":"CHN-9","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.26792,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2021-01-26","TRTSDTM":"2021-01-27 02:18:01","TRTEDTM":"2022-02-18 10:34:01","TRT01SDTM":"2021-01-27 02:18:01","TRT01EDTM":"2021-02-18 04:34:01","TRT02SDTM":"2021-02-18 04:34:01","TRT02EDTM":"2022-02-18 10:34:01","AP01SDTM":"2021-01-27 02:18:01","AP01EDTM":"2021-02-18 04:34:01","AP02SDTM":"2021-02-18 04:34:01","AP02EDTM":"2022-02-18 10:34:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":388,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":398,"ADTHAUT":"No","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7883,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.75502,"AVALU":"mg/L","BASE2":8.07315,"BASE":8.95469,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.31813,"PCHG2":-3.94063,"CHG":-1.19967,"PCHG":-13.3971,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-05-29 02:18:01","ADY":122,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-11","SUBJID":"id-11","SITEID":"CHN-9","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.26792,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2021-01-26","TRTSDTM":"2021-01-27 02:18:01","TRTEDTM":"2022-02-18 10:34:01","TRT01SDTM":"2021-01-27 02:18:01","TRT01EDTM":"2021-02-18 04:34:01","TRT02SDTM":"2021-02-18 04:34:01","TRT02EDTM":"2022-02-18 10:34:01","AP01SDTM":"2021-01-27 02:18:01","AP01EDTM":"2021-02-18 04:34:01","AP02SDTM":"2021-02-18 04:34:01","AP02EDTM":"2022-02-18 10:34:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":388,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":398,"ADTHAUT":"No","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3525,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.6897,"AVALU":"mg/L","BASE2":8.07315,"BASE":8.95469,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.61655,"PCHG2":20.02375,"CHG":0.73501,"PCHG":8.20813,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-14 02:18:01","ADY":168,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-11","SUBJID":"id-11","SITEID":"CHN-9","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.26792,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2021-01-26","TRTSDTM":"2021-01-27 02:18:01","TRTEDTM":"2022-02-18 10:34:01","TRT01SDTM":"2021-01-27 02:18:01","TRT01EDTM":"2021-02-18 04:34:01","TRT02SDTM":"2021-02-18 04:34:01","TRT02EDTM":"2022-02-18 10:34:01","AP01SDTM":"2021-01-27 02:18:01","AP01EDTM":"2021-02-18 04:34:01","AP02SDTM":"2021-02-18 04:34:01","AP02EDTM":"2022-02-18 10:34:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":388,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":398,"ADTHAUT":"No","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5083,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.9258,"AVALU":"mg/L","BASE2":8.07315,"BASE":8.95469,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14735,"PCHG2":-1.82519,"CHG":-1.02889,"PCHG":-11.48991,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-10-30 02:18:01","ADY":276,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-11","SUBJID":"id-11","SITEID":"CHN-9","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.26792,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2021-01-26","TRTSDTM":"2021-01-27 02:18:01","TRTEDTM":"2022-02-18 10:34:01","TRT01SDTM":"2021-01-27 02:18:01","TRT01EDTM":"2021-02-18 04:34:01","TRT02SDTM":"2021-02-18 04:34:01","TRT02EDTM":"2022-02-18 10:34:01","AP01SDTM":"2021-01-27 02:18:01","AP01EDTM":"2021-02-18 04:34:01","AP02SDTM":"2021-02-18 04:34:01","AP02EDTM":"2022-02-18 10:34:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":388,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":398,"ADTHAUT":"No","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3180,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.481,"AVALU":"mg/L","BASE2":8.07315,"BASE":8.95469,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.40785,"PCHG2":29.82537,"CHG":1.52631,"PCHG":17.04484,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-12-16 02:18:01","ADY":323,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-11","SUBJID":"id-11","SITEID":"CHN-9","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.26792,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2021-01-26","TRTSDTM":"2021-01-27 02:18:01","TRTEDTM":"2022-02-18 10:34:01","TRT01SDTM":"2021-01-27 02:18:01","TRT01EDTM":"2021-02-18 04:34:01","TRT02SDTM":"2021-02-18 04:34:01","TRT02EDTM":"2022-02-18 10:34:01","AP01SDTM":"2021-01-27 02:18:01","AP01EDTM":"2021-02-18 04:34:01","AP02SDTM":"2021-02-18 04:34:01","AP02EDTM":"2022-02-18 10:34:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":388,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":398,"ADTHAUT":"No","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7170,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.27965,"AVALU":"mg/L","BASE2":8.07315,"BASE":8.95469,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.20649,"PCHG2":27.33126,"CHG":1.32496,"PCHG":14.79626,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-02-07 02:18:01","ADY":376,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-11","SUBJID":"id-11","SITEID":"CHN-9","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.26792,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2021-01-26","TRTSDTM":"2021-01-27 02:18:01","TRTEDTM":"2022-02-18 10:34:01","TRT01SDTM":"2021-01-27 02:18:01","TRT01EDTM":"2021-02-18 04:34:01","TRT02SDTM":"2021-02-18 04:34:01","TRT02EDTM":"2022-02-18 10:34:01","AP01SDTM":"2021-01-27 02:18:01","AP01EDTM":"2021-02-18 04:34:01","AP02SDTM":"2021-02-18 04:34:01","AP02EDTM":"2022-02-18 10:34:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":388,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":398,"ADTHAUT":"No","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4042,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80468,"AVALU":"g/L","BASE2":2.80468,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-05 02:18:01","ADY":37,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-11","SUBJID":"id-11","SITEID":"CHN-9","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.26792,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2021-01-26","TRTSDTM":"2021-01-27 02:18:01","TRTEDTM":"2022-02-18 10:34:01","TRT01SDTM":"2021-01-27 02:18:01","TRT01EDTM":"2021-02-18 04:34:01","TRT02SDTM":"2021-02-18 04:34:01","TRT02EDTM":"2022-02-18 10:34:01","AP01SDTM":"2021-01-27 02:18:01","AP01EDTM":"2021-02-18 04:34:01","AP02SDTM":"2021-02-18 04:34:01","AP02EDTM":"2022-02-18 10:34:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":388,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":398,"ADTHAUT":"No","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7314,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88706,"AVALU":"g/L","BASE2":2.80468,"BASE":2.88706,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.08239,"PCHG2":2.93758,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-19 02:18:01","ADY":82,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-11","SUBJID":"id-11","SITEID":"CHN-9","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.26792,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2021-01-26","TRTSDTM":"2021-01-27 02:18:01","TRTEDTM":"2022-02-18 10:34:01","TRT01SDTM":"2021-01-27 02:18:01","TRT01EDTM":"2021-02-18 04:34:01","TRT02SDTM":"2021-02-18 04:34:01","TRT02EDTM":"2022-02-18 10:34:01","AP01SDTM":"2021-01-27 02:18:01","AP01EDTM":"2021-02-18 04:34:01","AP02SDTM":"2021-02-18 04:34:01","AP02EDTM":"2022-02-18 10:34:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":388,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":398,"ADTHAUT":"No","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5422,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04056,"AVALU":"g/L","BASE2":2.80468,"BASE":2.88706,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.23589,"PCHG2":8.41043,"CHG":0.1535,"PCHG":5.31667,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2021-05-29 02:18:01","ADY":122,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-11","SUBJID":"id-11","SITEID":"CHN-9","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.26792,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2021-01-26","TRTSDTM":"2021-01-27 02:18:01","TRTEDTM":"2022-02-18 10:34:01","TRT01SDTM":"2021-01-27 02:18:01","TRT01EDTM":"2021-02-18 04:34:01","TRT02SDTM":"2021-02-18 04:34:01","TRT02EDTM":"2022-02-18 10:34:01","AP01SDTM":"2021-01-27 02:18:01","AP01EDTM":"2021-02-18 04:34:01","AP02SDTM":"2021-02-18 04:34:01","AP02EDTM":"2022-02-18 10:34:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":388,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":398,"ADTHAUT":"No","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2758,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82547,"AVALU":"g/L","BASE2":2.80468,"BASE":2.88706,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02079,"PCHG2":0.7413,"CHG":-0.0616,"PCHG":-2.13361,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-14 02:18:01","ADY":168,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-11","SUBJID":"id-11","SITEID":"CHN-9","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.26792,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2021-01-26","TRTSDTM":"2021-01-27 02:18:01","TRTEDTM":"2022-02-18 10:34:01","TRT01SDTM":"2021-01-27 02:18:01","TRT01EDTM":"2021-02-18 04:34:01","TRT02SDTM":"2021-02-18 04:34:01","TRT02EDTM":"2022-02-18 10:34:01","AP01SDTM":"2021-01-27 02:18:01","AP01EDTM":"2021-02-18 04:34:01","AP02SDTM":"2021-02-18 04:34:01","AP02EDTM":"2022-02-18 10:34:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":388,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":398,"ADTHAUT":"No","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1043,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91586,"AVALU":"g/L","BASE2":2.80468,"BASE":2.88706,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11118,"PCHG2":3.96427,"CHG":0.0288,"PCHG":0.99739,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-30 02:18:01","ADY":276,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-11","SUBJID":"id-11","SITEID":"CHN-9","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.26792,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2021-01-26","TRTSDTM":"2021-01-27 02:18:01","TRTEDTM":"2022-02-18 10:34:01","TRT01SDTM":"2021-01-27 02:18:01","TRT01EDTM":"2021-02-18 04:34:01","TRT02SDTM":"2021-02-18 04:34:01","TRT02EDTM":"2022-02-18 10:34:01","AP01SDTM":"2021-01-27 02:18:01","AP01EDTM":"2021-02-18 04:34:01","AP02SDTM":"2021-02-18 04:34:01","AP02EDTM":"2022-02-18 10:34:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":388,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":398,"ADTHAUT":"No","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5952,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84618,"AVALU":"g/L","BASE2":2.80468,"BASE":2.88706,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04151,"PCHG2":1.47997,"CHG":-0.04088,"PCHG":-1.41601,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-16 02:18:01","ADY":323,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-11","SUBJID":"id-11","SITEID":"CHN-9","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"Y","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.26792,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2021-01-26","TRTSDTM":"2021-01-27 02:18:01","TRTEDTM":"2022-02-18 10:34:01","TRT01SDTM":"2021-01-27 02:18:01","TRT01EDTM":"2021-02-18 04:34:01","TRT02SDTM":"2021-02-18 04:34:01","TRT02EDTM":"2022-02-18 10:34:01","AP01SDTM":"2021-01-27 02:18:01","AP01EDTM":"2021-02-18 04:34:01","AP02SDTM":"2021-02-18 04:34:01","AP02EDTM":"2022-02-18 10:34:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":388,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":398,"ADTHAUT":"No","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7421,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01611,"AVALU":"g/L","BASE2":2.80468,"BASE":2.88706,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.21144,"PCHG2":7.53876,"CHG":0.12905,"PCHG":4.46988,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-02-07 02:18:01","ADY":376,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-147","SUBJID":"id-147","SITEID":"CHN-9","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.54647,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-02-03","TRTSDTM":"2020-02-06 16:03:48","TRT01SDTM":"2020-02-06 16:03:48","AP01SDTM":"2020-02-06 16:03:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1116,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.91917,"AVALU":"U/L","BASE2":5.91917,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-05-03 16:03:48","ADY":87,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-147","SUBJID":"id-147","SITEID":"CHN-9","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.54647,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-02-03","TRTSDTM":"2020-02-06 16:03:48","TRT01SDTM":"2020-02-06 16:03:48","AP01SDTM":"2020-02-06 16:03:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7535,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.15068,"AVALU":"U/L","BASE2":5.91917,"BASE":17.15068,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":11.2315,"PCHG2":189.74787,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-14 16:03:48","ADY":129,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-147","SUBJID":"id-147","SITEID":"CHN-9","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.54647,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-02-03","TRTSDTM":"2020-02-06 16:03:48","TRT01SDTM":"2020-02-06 16:03:48","AP01SDTM":"2020-02-06 16:03:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4185,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.81425,"AVALU":"U/L","BASE2":5.91917,"BASE":17.15068,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.10492,"PCHG2":-52.45533,"CHG":-14.33642,"PCHG":-83.59102,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-09-06 16:03:48","ADY":213,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-147","SUBJID":"id-147","SITEID":"CHN-9","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.54647,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-02-03","TRTSDTM":"2020-02-06 16:03:48","TRT01SDTM":"2020-02-06 16:03:48","AP01SDTM":"2020-02-06 16:03:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":867,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.5286,"AVALU":"U/L","BASE2":5.91917,"BASE":17.15068,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.60943,"PCHG2":128.55569,"CHG":-3.62207,"PCHG":-21.11911,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-15 16:03:48","ADY":252,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-147","SUBJID":"id-147","SITEID":"CHN-9","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.54647,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-02-03","TRTSDTM":"2020-02-06 16:03:48","TRT01SDTM":"2020-02-06 16:03:48","AP01SDTM":"2020-02-06 16:03:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6087,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.98495,"AVALU":"U/L","BASE2":5.91917,"BASE":17.15068,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.93422,"PCHG2":-32.67723,"CHG":-13.16572,"PCHG":-76.76505,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-11-08 16:03:48","ADY":276,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-147","SUBJID":"id-147","SITEID":"CHN-9","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.54647,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-02-03","TRTSDTM":"2020-02-06 16:03:48","TRT01SDTM":"2020-02-06 16:03:48","AP01SDTM":"2020-02-06 16:03:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5823,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":41.28167,"AVALU":"U/L","BASE2":5.91917,"BASE":17.15068,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":35.3625,"PCHG2":597.42301,"CHG":24.13099,"PCHG":140.69996,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-02 16:03:48","ADY":300,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-147","SUBJID":"id-147","SITEID":"CHN-9","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.54647,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-02-03","TRTSDTM":"2020-02-06 16:03:48","TRT01SDTM":"2020-02-06 16:03:48","AP01SDTM":"2020-02-06 16:03:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":773,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":37.29173,"AVALU":"U/L","BASE2":5.91917,"BASE":17.15068,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":31.37256,"PCHG2":530.01604,"CHG":20.14106,"PCHG":117.43595,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-24 16:03:48","ADY":504,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-147","SUBJID":"id-147","SITEID":"CHN-9","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.54647,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-02-03","TRTSDTM":"2020-02-06 16:03:48","TRT01SDTM":"2020-02-06 16:03:48","AP01SDTM":"2020-02-06 16:03:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3131,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.80571,"AVALU":"mg/L","BASE2":7.80571,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-05-03 16:03:48","ADY":87,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-147","SUBJID":"id-147","SITEID":"CHN-9","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.54647,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-02-03","TRTSDTM":"2020-02-06 16:03:48","TRT01SDTM":"2020-02-06 16:03:48","AP01SDTM":"2020-02-06 16:03:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4183,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.92362,"AVALU":"mg/L","BASE2":7.80571,"BASE":9.92362,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.11792,"PCHG2":27.1329,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-14 16:03:48","ADY":129,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-147","SUBJID":"id-147","SITEID":"CHN-9","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.54647,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-02-03","TRTSDTM":"2020-02-06 16:03:48","TRT01SDTM":"2020-02-06 16:03:48","AP01SDTM":"2020-02-06 16:03:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3060,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.61867,"AVALU":"mg/L","BASE2":7.80571,"BASE":9.92362,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.81296,"PCHG2":23.22605,"CHG":-0.30496,"PCHG":-3.07305,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-06 16:03:48","ADY":213,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-147","SUBJID":"id-147","SITEID":"CHN-9","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.54647,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-02-03","TRTSDTM":"2020-02-06 16:03:48","TRT01SDTM":"2020-02-06 16:03:48","AP01SDTM":"2020-02-06 16:03:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3520,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.56094,"AVALU":"mg/L","BASE2":7.80571,"BASE":9.92362,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.75523,"PCHG2":22.4865,"CHG":-0.36268,"PCHG":-3.65476,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-15 16:03:48","ADY":252,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-147","SUBJID":"id-147","SITEID":"CHN-9","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.54647,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-02-03","TRTSDTM":"2020-02-06 16:03:48","TRT01SDTM":"2020-02-06 16:03:48","AP01SDTM":"2020-02-06 16:03:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1368,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.65079,"AVALU":"mg/L","BASE2":7.80571,"BASE":9.92362,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.84508,"PCHG2":23.63762,"CHG":-0.27283,"PCHG":-2.74931,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-08 16:03:48","ADY":276,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-147","SUBJID":"id-147","SITEID":"CHN-9","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.54647,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-02-03","TRTSDTM":"2020-02-06 16:03:48","TRT01SDTM":"2020-02-06 16:03:48","AP01SDTM":"2020-02-06 16:03:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3995,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.10428,"AVALU":"mg/L","BASE2":7.80571,"BASE":9.92362,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.70143,"PCHG2":-8.98607,"CHG":-2.81934,"PCHG":-28.4104,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-12-02 16:03:48","ADY":300,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-147","SUBJID":"id-147","SITEID":"CHN-9","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.54647,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-02-03","TRTSDTM":"2020-02-06 16:03:48","TRT01SDTM":"2020-02-06 16:03:48","AP01SDTM":"2020-02-06 16:03:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1081,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.83156,"AVALU":"mg/L","BASE2":7.80571,"BASE":9.92362,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.02585,"PCHG2":25.95349,"CHG":-0.09206,"PCHG":-0.9277,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-24 16:03:48","ADY":504,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-147","SUBJID":"id-147","SITEID":"CHN-9","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.54647,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-02-03","TRTSDTM":"2020-02-06 16:03:48","TRT01SDTM":"2020-02-06 16:03:48","AP01SDTM":"2020-02-06 16:03:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2380,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88358,"AVALU":"g/L","BASE2":2.88358,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-03 16:03:48","ADY":87,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-147","SUBJID":"id-147","SITEID":"CHN-9","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.54647,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-02-03","TRTSDTM":"2020-02-06 16:03:48","TRT01SDTM":"2020-02-06 16:03:48","AP01SDTM":"2020-02-06 16:03:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6965,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88486,"AVALU":"g/L","BASE2":2.88358,"BASE":2.88486,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.00127,"PCHG2":0.04418,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-14 16:03:48","ADY":129,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-147","SUBJID":"id-147","SITEID":"CHN-9","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.54647,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-02-03","TRTSDTM":"2020-02-06 16:03:48","TRT01SDTM":"2020-02-06 16:03:48","AP01SDTM":"2020-02-06 16:03:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1225,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98335,"AVALU":"g/L","BASE2":2.88358,"BASE":2.88486,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09977,"PCHG2":3.45988,"CHG":0.09849,"PCHG":3.4142,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-06 16:03:48","ADY":213,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-147","SUBJID":"id-147","SITEID":"CHN-9","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.54647,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-02-03","TRTSDTM":"2020-02-06 16:03:48","TRT01SDTM":"2020-02-06 16:03:48","AP01SDTM":"2020-02-06 16:03:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7552,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85964,"AVALU":"g/L","BASE2":2.88358,"BASE":2.88486,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02395,"PCHG2":-0.83043,"CHG":-0.02522,"PCHG":-0.87423,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-15 16:03:48","ADY":252,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-147","SUBJID":"id-147","SITEID":"CHN-9","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.54647,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-02-03","TRTSDTM":"2020-02-06 16:03:48","TRT01SDTM":"2020-02-06 16:03:48","AP01SDTM":"2020-02-06 16:03:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2956,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.59908,"AVALU":"g/L","BASE2":2.88358,"BASE":2.88486,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.2845,"PCHG2":-9.86627,"CHG":-0.28578,"PCHG":-9.90607,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-08 16:03:48","ADY":276,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-147","SUBJID":"id-147","SITEID":"CHN-9","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.54647,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-02-03","TRTSDTM":"2020-02-06 16:03:48","TRT01SDTM":"2020-02-06 16:03:48","AP01SDTM":"2020-02-06 16:03:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5243,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.07457,"AVALU":"g/L","BASE2":2.88358,"BASE":2.88486,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.19098,"PCHG2":6.62312,"CHG":0.18971,"PCHG":6.57604,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-12-02 16:03:48","ADY":300,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-147","SUBJID":"id-147","SITEID":"CHN-9","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.54647,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-02-03","TRTSDTM":"2020-02-06 16:03:48","TRT01SDTM":"2020-02-06 16:03:48","AP01SDTM":"2020-02-06 16:03:48","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7563,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05585,"AVALU":"g/L","BASE2":2.88358,"BASE":2.88486,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17227,"PCHG2":5.97407,"CHG":0.17099,"PCHG":5.92727,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2021-06-24 16:03:48","ADY":504,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-374","SUBJID":"id-374","SITEID":"CHN-9","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.75803,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-14","TRTSDTM":"2020-11-17 12:08:20","TRTEDTM":"2023-11-18 06:08:20","TRT01SDTM":"2020-11-17 12:08:20","TRT01EDTM":"2022-11-18 00:08:20","TRT02SDTM":"2022-11-18 00:08:20","TRT02EDTM":"2023-11-18 06:08:20","AP01SDTM":"2020-11-17 12:08:20","AP01EDTM":"2022-11-18 00:08:20","AP02SDTM":"2022-11-18 00:08:20","AP02EDTM":"2023-11-18 06:08:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2675,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.77268,"AVALU":"U/L","BASE2":24.77268,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-18 12:08:20","ADY":62,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-374","SUBJID":"id-374","SITEID":"CHN-9","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.75803,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-14","TRTSDTM":"2020-11-17 12:08:20","TRTEDTM":"2023-11-18 06:08:20","TRT01SDTM":"2020-11-17 12:08:20","TRT01EDTM":"2022-11-18 00:08:20","TRT02SDTM":"2022-11-18 00:08:20","TRT02EDTM":"2023-11-18 06:08:20","AP01SDTM":"2020-11-17 12:08:20","AP01EDTM":"2022-11-18 00:08:20","AP02SDTM":"2022-11-18 00:08:20","AP02EDTM":"2023-11-18 06:08:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":659,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.49602,"AVALU":"U/L","BASE2":24.77268,"BASE":18.49602,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-6.27667,"PCHG2":-25.33706,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-24 12:08:20","ADY":433,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-374","SUBJID":"id-374","SITEID":"CHN-9","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.75803,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-14","TRTSDTM":"2020-11-17 12:08:20","TRTEDTM":"2023-11-18 06:08:20","TRT01SDTM":"2020-11-17 12:08:20","TRT01EDTM":"2022-11-18 00:08:20","TRT02SDTM":"2022-11-18 00:08:20","TRT02EDTM":"2023-11-18 06:08:20","AP01SDTM":"2020-11-17 12:08:20","AP01EDTM":"2022-11-18 00:08:20","AP02SDTM":"2022-11-18 00:08:20","AP02EDTM":"2023-11-18 06:08:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4335,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.29754,"AVALU":"U/L","BASE2":24.77268,"BASE":18.49602,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.47514,"PCHG2":-5.95471,"CHG":4.80153,"PCHG":25.9598,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-19 12:08:20","ADY":548,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-374","SUBJID":"id-374","SITEID":"CHN-9","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.75803,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-14","TRTSDTM":"2020-11-17 12:08:20","TRTEDTM":"2023-11-18 06:08:20","TRT01SDTM":"2020-11-17 12:08:20","TRT01EDTM":"2022-11-18 00:08:20","TRT02SDTM":"2022-11-18 00:08:20","TRT02EDTM":"2023-11-18 06:08:20","AP01SDTM":"2020-11-17 12:08:20","AP01EDTM":"2022-11-18 00:08:20","AP02SDTM":"2022-11-18 00:08:20","AP02EDTM":"2023-11-18 06:08:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6644,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.73203,"AVALU":"U/L","BASE2":24.77268,"BASE":18.49602,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.04066,"PCHG2":-12.27423,"CHG":3.23601,"PCHG":17.49573,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-03 12:08:20","ADY":655,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-374","SUBJID":"id-374","SITEID":"CHN-9","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.75803,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-14","TRTSDTM":"2020-11-17 12:08:20","TRTEDTM":"2023-11-18 06:08:20","TRT01SDTM":"2020-11-17 12:08:20","TRT01EDTM":"2022-11-18 00:08:20","TRT02SDTM":"2022-11-18 00:08:20","TRT02EDTM":"2023-11-18 06:08:20","AP01SDTM":"2020-11-17 12:08:20","AP01EDTM":"2022-11-18 00:08:20","AP02SDTM":"2022-11-18 00:08:20","AP02EDTM":"2023-11-18 06:08:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4442,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.47972,"AVALU":"U/L","BASE2":24.77268,"BASE":18.49602,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.70703,"PCHG2":14.96418,"CHG":9.9837,"PCHG":53.97757,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-06 12:08:20","ADY":658,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-374","SUBJID":"id-374","SITEID":"CHN-9","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.75803,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-14","TRTSDTM":"2020-11-17 12:08:20","TRTEDTM":"2023-11-18 06:08:20","TRT01SDTM":"2020-11-17 12:08:20","TRT01EDTM":"2022-11-18 00:08:20","TRT02SDTM":"2022-11-18 00:08:20","TRT02EDTM":"2023-11-18 06:08:20","AP01SDTM":"2020-11-17 12:08:20","AP01EDTM":"2022-11-18 00:08:20","AP02SDTM":"2022-11-18 00:08:20","AP02EDTM":"2023-11-18 06:08:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7005,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.71315,"AVALU":"U/L","BASE2":24.77268,"BASE":18.49602,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-18.05953,"PCHG2":-72.90099,"CHG":-11.78286,"PCHG":-63.70487,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2023-10-19 12:08:20","ADY":1066,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-374","SUBJID":"id-374","SITEID":"CHN-9","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.75803,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-14","TRTSDTM":"2020-11-17 12:08:20","TRTEDTM":"2023-11-18 06:08:20","TRT01SDTM":"2020-11-17 12:08:20","TRT01EDTM":"2022-11-18 00:08:20","TRT02SDTM":"2022-11-18 00:08:20","TRT02EDTM":"2023-11-18 06:08:20","AP01SDTM":"2020-11-17 12:08:20","AP01EDTM":"2022-11-18 00:08:20","AP02SDTM":"2022-11-18 00:08:20","AP02EDTM":"2023-11-18 06:08:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6665,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.06463,"AVALU":"U/L","BASE2":24.77268,"BASE":18.49602,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-19.70805,"PCHG2":-79.55557,"CHG":-13.43138,"PCHG":-72.6177,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2023-11-06 12:08:20","ADY":1084,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-374","SUBJID":"id-374","SITEID":"CHN-9","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.75803,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-14","TRTSDTM":"2020-11-17 12:08:20","TRTEDTM":"2023-11-18 06:08:20","TRT01SDTM":"2020-11-17 12:08:20","TRT01EDTM":"2022-11-18 00:08:20","TRT02SDTM":"2022-11-18 00:08:20","TRT02EDTM":"2023-11-18 06:08:20","AP01SDTM":"2020-11-17 12:08:20","AP01EDTM":"2022-11-18 00:08:20","AP02SDTM":"2022-11-18 00:08:20","AP02EDTM":"2023-11-18 06:08:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5585,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.02507,"AVALU":"mg/L","BASE2":10.02507,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-01-18 12:08:20","ADY":62,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-374","SUBJID":"id-374","SITEID":"CHN-9","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.75803,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-14","TRTSDTM":"2020-11-17 12:08:20","TRTEDTM":"2023-11-18 06:08:20","TRT01SDTM":"2020-11-17 12:08:20","TRT01EDTM":"2022-11-18 00:08:20","TRT02SDTM":"2022-11-18 00:08:20","TRT02EDTM":"2023-11-18 06:08:20","AP01SDTM":"2020-11-17 12:08:20","AP01EDTM":"2022-11-18 00:08:20","AP02SDTM":"2022-11-18 00:08:20","AP02EDTM":"2023-11-18 06:08:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2825,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.7229,"AVALU":"mg/L","BASE2":10.02507,"BASE":9.7229,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.30217,"PCHG2":-3.01412,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-24 12:08:20","ADY":433,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-374","SUBJID":"id-374","SITEID":"CHN-9","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.75803,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-14","TRTSDTM":"2020-11-17 12:08:20","TRTEDTM":"2023-11-18 06:08:20","TRT01SDTM":"2020-11-17 12:08:20","TRT01EDTM":"2022-11-18 00:08:20","TRT02SDTM":"2022-11-18 00:08:20","TRT02EDTM":"2023-11-18 06:08:20","AP01SDTM":"2020-11-17 12:08:20","AP01EDTM":"2022-11-18 00:08:20","AP02SDTM":"2022-11-18 00:08:20","AP02EDTM":"2023-11-18 06:08:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3062,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.94195,"AVALU":"mg/L","BASE2":10.02507,"BASE":9.7229,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.08312,"PCHG2":-10.80407,"CHG":-0.78095,"PCHG":-8.03205,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-19 12:08:20","ADY":548,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-374","SUBJID":"id-374","SITEID":"CHN-9","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.75803,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-14","TRTSDTM":"2020-11-17 12:08:20","TRTEDTM":"2023-11-18 06:08:20","TRT01SDTM":"2020-11-17 12:08:20","TRT01EDTM":"2022-11-18 00:08:20","TRT02SDTM":"2022-11-18 00:08:20","TRT02EDTM":"2023-11-18 06:08:20","AP01SDTM":"2020-11-17 12:08:20","AP01EDTM":"2022-11-18 00:08:20","AP02SDTM":"2022-11-18 00:08:20","AP02EDTM":"2023-11-18 06:08:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3467,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.74007,"AVALU":"mg/L","BASE2":10.02507,"BASE":9.7229,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.285,"PCHG2":-12.81788,"CHG":-0.98283,"PCHG":-10.10844,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-03 12:08:20","ADY":655,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-374","SUBJID":"id-374","SITEID":"CHN-9","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.75803,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-14","TRTSDTM":"2020-11-17 12:08:20","TRTEDTM":"2023-11-18 06:08:20","TRT01SDTM":"2020-11-17 12:08:20","TRT01EDTM":"2022-11-18 00:08:20","TRT02SDTM":"2022-11-18 00:08:20","TRT02EDTM":"2023-11-18 06:08:20","AP01SDTM":"2020-11-17 12:08:20","AP01EDTM":"2022-11-18 00:08:20","AP02SDTM":"2022-11-18 00:08:20","AP02EDTM":"2023-11-18 06:08:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1506,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.22082,"AVALU":"mg/L","BASE2":10.02507,"BASE":9.7229,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.80425,"PCHG2":-17.99737,"CHG":-1.50208,"PCHG":-15.4489,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-06 12:08:20","ADY":658,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-374","SUBJID":"id-374","SITEID":"CHN-9","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.75803,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-14","TRTSDTM":"2020-11-17 12:08:20","TRTEDTM":"2023-11-18 06:08:20","TRT01SDTM":"2020-11-17 12:08:20","TRT01EDTM":"2022-11-18 00:08:20","TRT02SDTM":"2022-11-18 00:08:20","TRT02EDTM":"2023-11-18 06:08:20","AP01SDTM":"2020-11-17 12:08:20","AP01EDTM":"2022-11-18 00:08:20","AP02SDTM":"2022-11-18 00:08:20","AP02EDTM":"2023-11-18 06:08:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6291,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.14272,"AVALU":"mg/L","BASE2":10.02507,"BASE":9.7229,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.88235,"PCHG2":-28.75138,"CHG":-2.58018,"PCHG":-26.53712,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2023-10-19 12:08:20","ADY":1066,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-374","SUBJID":"id-374","SITEID":"CHN-9","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.75803,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-14","TRTSDTM":"2020-11-17 12:08:20","TRTEDTM":"2023-11-18 06:08:20","TRT01SDTM":"2020-11-17 12:08:20","TRT01EDTM":"2022-11-18 00:08:20","TRT02SDTM":"2022-11-18 00:08:20","TRT02EDTM":"2023-11-18 06:08:20","AP01SDTM":"2020-11-17 12:08:20","AP01EDTM":"2022-11-18 00:08:20","AP02SDTM":"2022-11-18 00:08:20","AP02EDTM":"2023-11-18 06:08:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5886,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.41945,"AVALU":"mg/L","BASE2":10.02507,"BASE":9.7229,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.60562,"PCHG2":-16.01609,"CHG":-1.30346,"PCHG":-13.40604,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-11-06 12:08:20","ADY":1084,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-374","SUBJID":"id-374","SITEID":"CHN-9","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.75803,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-14","TRTSDTM":"2020-11-17 12:08:20","TRTEDTM":"2023-11-18 06:08:20","TRT01SDTM":"2020-11-17 12:08:20","TRT01EDTM":"2022-11-18 00:08:20","TRT02SDTM":"2022-11-18 00:08:20","TRT02EDTM":"2023-11-18 06:08:20","AP01SDTM":"2020-11-17 12:08:20","AP01EDTM":"2022-11-18 00:08:20","AP02SDTM":"2022-11-18 00:08:20","AP02EDTM":"2023-11-18 06:08:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":713,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7657,"AVALU":"g/L","BASE2":2.7657,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-18 12:08:20","ADY":62,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-374","SUBJID":"id-374","SITEID":"CHN-9","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.75803,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-14","TRTSDTM":"2020-11-17 12:08:20","TRTEDTM":"2023-11-18 06:08:20","TRT01SDTM":"2020-11-17 12:08:20","TRT01EDTM":"2022-11-18 00:08:20","TRT02SDTM":"2022-11-18 00:08:20","TRT02EDTM":"2023-11-18 06:08:20","AP01SDTM":"2020-11-17 12:08:20","AP01EDTM":"2022-11-18 00:08:20","AP02SDTM":"2022-11-18 00:08:20","AP02EDTM":"2023-11-18 06:08:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4555,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99124,"AVALU":"g/L","BASE2":2.7657,"BASE":2.99124,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.22554,"PCHG2":8.15479,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-24 12:08:20","ADY":433,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-374","SUBJID":"id-374","SITEID":"CHN-9","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.75803,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-14","TRTSDTM":"2020-11-17 12:08:20","TRTEDTM":"2023-11-18 06:08:20","TRT01SDTM":"2020-11-17 12:08:20","TRT01EDTM":"2022-11-18 00:08:20","TRT02SDTM":"2022-11-18 00:08:20","TRT02EDTM":"2023-11-18 06:08:20","AP01SDTM":"2020-11-17 12:08:20","AP01EDTM":"2022-11-18 00:08:20","AP02SDTM":"2022-11-18 00:08:20","AP02EDTM":"2023-11-18 06:08:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5361,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93954,"AVALU":"g/L","BASE2":2.7657,"BASE":2.99124,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17384,"PCHG2":6.2856,"CHG":-0.0517,"PCHG":-1.72826,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-19 12:08:20","ADY":548,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-374","SUBJID":"id-374","SITEID":"CHN-9","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.75803,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-14","TRTSDTM":"2020-11-17 12:08:20","TRTEDTM":"2023-11-18 06:08:20","TRT01SDTM":"2020-11-17 12:08:20","TRT01EDTM":"2022-11-18 00:08:20","TRT02SDTM":"2022-11-18 00:08:20","TRT02EDTM":"2023-11-18 06:08:20","AP01SDTM":"2020-11-17 12:08:20","AP01EDTM":"2022-11-18 00:08:20","AP02SDTM":"2022-11-18 00:08:20","AP02EDTM":"2023-11-18 06:08:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5443,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98773,"AVALU":"g/L","BASE2":2.7657,"BASE":2.99124,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.22203,"PCHG2":8.02797,"CHG":-0.00351,"PCHG":-0.11726,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-03 12:08:20","ADY":655,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-374","SUBJID":"id-374","SITEID":"CHN-9","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.75803,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-14","TRTSDTM":"2020-11-17 12:08:20","TRTEDTM":"2023-11-18 06:08:20","TRT01SDTM":"2020-11-17 12:08:20","TRT01EDTM":"2022-11-18 00:08:20","TRT02SDTM":"2022-11-18 00:08:20","TRT02EDTM":"2023-11-18 06:08:20","AP01SDTM":"2020-11-17 12:08:20","AP01EDTM":"2022-11-18 00:08:20","AP02SDTM":"2022-11-18 00:08:20","AP02EDTM":"2023-11-18 06:08:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":224,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82516,"AVALU":"g/L","BASE2":2.7657,"BASE":2.99124,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05946,"PCHG2":2.14978,"CHG":-0.16608,"PCHG":-5.55224,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-06 12:08:20","ADY":658,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-374","SUBJID":"id-374","SITEID":"CHN-9","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.75803,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-14","TRTSDTM":"2020-11-17 12:08:20","TRTEDTM":"2023-11-18 06:08:20","TRT01SDTM":"2020-11-17 12:08:20","TRT01EDTM":"2022-11-18 00:08:20","TRT02SDTM":"2022-11-18 00:08:20","TRT02EDTM":"2023-11-18 06:08:20","AP01SDTM":"2020-11-17 12:08:20","AP01EDTM":"2022-11-18 00:08:20","AP02SDTM":"2022-11-18 00:08:20","AP02EDTM":"2023-11-18 06:08:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6071,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95546,"AVALU":"g/L","BASE2":2.7657,"BASE":2.99124,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18976,"PCHG2":6.86123,"CHG":-0.03578,"PCHG":-1.19603,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-10-19 12:08:20","ADY":1066,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-CHN-9-id-374","SUBJID":"id-374","SITEID":"CHN-9","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"CHN","DTHFL":"N","INVID":"INV ID CHN-9","INVNAM":"Dr. CHN-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.75803,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-14","TRTSDTM":"2020-11-17 12:08:20","TRTEDTM":"2023-11-18 06:08:20","TRT01SDTM":"2020-11-17 12:08:20","TRT01EDTM":"2022-11-18 00:08:20","TRT02SDTM":"2022-11-18 00:08:20","TRT02EDTM":"2023-11-18 06:08:20","AP01SDTM":"2020-11-17 12:08:20","AP01EDTM":"2022-11-18 00:08:20","AP02SDTM":"2022-11-18 00:08:20","AP02EDTM":"2023-11-18 06:08:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-13","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6854,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88328,"AVALU":"g/L","BASE2":2.7657,"BASE":2.99124,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11758,"PCHG2":4.25119,"CHG":-0.10796,"PCHG":-3.60928,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-11-06 12:08:20","ADY":1084,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-319","SUBJID":"id-319","SITEID":"GBR-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":1.83077,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-02","TRTSDTM":"2020-10-02 12:20:27","TRTEDTM":"2022-02-12 23:41:46","TRT01SDTM":"2020-10-02 12:20:27","TRT01EDTM":"2021-02-12 17:41:46","TRT02SDTM":"2021-02-12 17:41:46","TRT02EDTM":"2022-02-12 23:41:46","AP01SDTM":"2020-10-02 12:20:27","AP01EDTM":"2021-02-12 17:41:46","AP02SDTM":"2021-02-12 17:41:46","AP02EDTM":"2022-02-12 23:41:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":499,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":34,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":531,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6354,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.69789,"AVALU":"U/L","BASE2":0.69789,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-1","ADTM":"2021-03-26 12:20:27","ADY":175,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-319","SUBJID":"id-319","SITEID":"GBR-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":1.83077,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-02","TRTSDTM":"2020-10-02 12:20:27","TRTEDTM":"2022-02-12 23:41:46","TRT01SDTM":"2020-10-02 12:20:27","TRT01EDTM":"2021-02-12 17:41:46","TRT02SDTM":"2021-02-12 17:41:46","TRT02EDTM":"2022-02-12 23:41:46","AP01SDTM":"2020-10-02 12:20:27","AP01EDTM":"2021-02-12 17:41:46","AP02SDTM":"2021-02-12 17:41:46","AP02EDTM":"2022-02-12 23:41:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":499,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":34,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":531,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2755,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.64251,"AVALU":"U/L","BASE2":0.69789,"BASE":6.64251,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":5.94462,"PCHG2":851.80187,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2021-05-01 12:20:27","ADY":211,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-319","SUBJID":"id-319","SITEID":"GBR-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":1.83077,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-02","TRTSDTM":"2020-10-02 12:20:27","TRTEDTM":"2022-02-12 23:41:46","TRT01SDTM":"2020-10-02 12:20:27","TRT01EDTM":"2021-02-12 17:41:46","TRT02SDTM":"2021-02-12 17:41:46","TRT02EDTM":"2022-02-12 23:41:46","AP01SDTM":"2020-10-02 12:20:27","AP01EDTM":"2021-02-12 17:41:46","AP02SDTM":"2021-02-12 17:41:46","AP02EDTM":"2022-02-12 23:41:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":499,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":34,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":531,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3402,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.86985,"AVALU":"U/L","BASE2":0.69789,"BASE":6.64251,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":17.17196,"PCHG2":2460.56187,"CHG":11.22734,"PCHG":169.02257,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-09-02 12:20:27","ADY":335,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-319","SUBJID":"id-319","SITEID":"GBR-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":1.83077,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-02","TRTSDTM":"2020-10-02 12:20:27","TRTEDTM":"2022-02-12 23:41:46","TRT01SDTM":"2020-10-02 12:20:27","TRT01EDTM":"2021-02-12 17:41:46","TRT02SDTM":"2021-02-12 17:41:46","TRT02EDTM":"2022-02-12 23:41:46","AP01SDTM":"2020-10-02 12:20:27","AP01EDTM":"2021-02-12 17:41:46","AP02SDTM":"2021-02-12 17:41:46","AP02EDTM":"2022-02-12 23:41:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":499,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":34,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":531,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2476,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.99964,"AVALU":"U/L","BASE2":0.69789,"BASE":6.64251,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.30175,"PCHG2":2622.44828,"CHG":12.35713,"PCHG":186.03099,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-09-13 12:20:27","ADY":346,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-319","SUBJID":"id-319","SITEID":"GBR-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":1.83077,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-02","TRTSDTM":"2020-10-02 12:20:27","TRTEDTM":"2022-02-12 23:41:46","TRT01SDTM":"2020-10-02 12:20:27","TRT01EDTM":"2021-02-12 17:41:46","TRT02SDTM":"2021-02-12 17:41:46","TRT02EDTM":"2022-02-12 23:41:46","AP01SDTM":"2020-10-02 12:20:27","AP01EDTM":"2021-02-12 17:41:46","AP02SDTM":"2021-02-12 17:41:46","AP02EDTM":"2022-02-12 23:41:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":499,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":34,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":531,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5222,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.56075,"AVALU":"U/L","BASE2":0.69789,"BASE":6.64251,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.86286,"PCHG2":1699.82382,"CHG":5.91824,"PCHG":89.09648,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-09-17 12:20:27","ADY":350,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-319","SUBJID":"id-319","SITEID":"GBR-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":1.83077,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-02","TRTSDTM":"2020-10-02 12:20:27","TRTEDTM":"2022-02-12 23:41:46","TRT01SDTM":"2020-10-02 12:20:27","TRT01EDTM":"2021-02-12 17:41:46","TRT02SDTM":"2021-02-12 17:41:46","TRT02EDTM":"2022-02-12 23:41:46","AP01SDTM":"2020-10-02 12:20:27","AP01EDTM":"2021-02-12 17:41:46","AP02SDTM":"2021-02-12 17:41:46","AP02EDTM":"2022-02-12 23:41:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":499,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":34,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":531,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5636,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.40664,"AVALU":"U/L","BASE2":0.69789,"BASE":6.64251,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":28.70876,"PCHG2":4113.66299,"CHG":22.76413,"PCHG":342.70379,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-11-07 12:20:27","ADY":401,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-319","SUBJID":"id-319","SITEID":"GBR-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":1.83077,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-02","TRTSDTM":"2020-10-02 12:20:27","TRTEDTM":"2022-02-12 23:41:46","TRT01SDTM":"2020-10-02 12:20:27","TRT01EDTM":"2021-02-12 17:41:46","TRT02SDTM":"2021-02-12 17:41:46","TRT02EDTM":"2022-02-12 23:41:46","AP01SDTM":"2020-10-02 12:20:27","AP01EDTM":"2021-02-12 17:41:46","AP02SDTM":"2021-02-12 17:41:46","AP02EDTM":"2022-02-12 23:41:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":499,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":34,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":531,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2228,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.5089,"AVALU":"U/L","BASE2":0.69789,"BASE":6.64251,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":28.81101,"PCHG2":4128.31499,"CHG":22.86639,"PCHG":344.24319,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-11-16 12:20:27","ADY":410,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-319","SUBJID":"id-319","SITEID":"GBR-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":1.83077,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-02","TRTSDTM":"2020-10-02 12:20:27","TRTEDTM":"2022-02-12 23:41:46","TRT01SDTM":"2020-10-02 12:20:27","TRT01EDTM":"2021-02-12 17:41:46","TRT02SDTM":"2021-02-12 17:41:46","TRT02EDTM":"2022-02-12 23:41:46","AP01SDTM":"2020-10-02 12:20:27","AP01EDTM":"2021-02-12 17:41:46","AP02SDTM":"2021-02-12 17:41:46","AP02EDTM":"2022-02-12 23:41:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":499,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":34,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":531,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5986,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.14497,"AVALU":"mg/L","BASE2":7.14497,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-03-26 12:20:27","ADY":175,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-319","SUBJID":"id-319","SITEID":"GBR-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":1.83077,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-02","TRTSDTM":"2020-10-02 12:20:27","TRTEDTM":"2022-02-12 23:41:46","TRT01SDTM":"2020-10-02 12:20:27","TRT01EDTM":"2021-02-12 17:41:46","TRT02SDTM":"2021-02-12 17:41:46","TRT02EDTM":"2022-02-12 23:41:46","AP01SDTM":"2020-10-02 12:20:27","AP01EDTM":"2021-02-12 17:41:46","AP02SDTM":"2021-02-12 17:41:46","AP02EDTM":"2022-02-12 23:41:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":499,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":34,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":531,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1588,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.36052,"AVALU":"mg/L","BASE2":7.14497,"BASE":8.36052,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.21556,"PCHG2":17.01276,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-01 12:20:27","ADY":211,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-319","SUBJID":"id-319","SITEID":"GBR-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":1.83077,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-02","TRTSDTM":"2020-10-02 12:20:27","TRTEDTM":"2022-02-12 23:41:46","TRT01SDTM":"2020-10-02 12:20:27","TRT01EDTM":"2021-02-12 17:41:46","TRT02SDTM":"2021-02-12 17:41:46","TRT02EDTM":"2022-02-12 23:41:46","AP01SDTM":"2020-10-02 12:20:27","AP01EDTM":"2021-02-12 17:41:46","AP02SDTM":"2021-02-12 17:41:46","AP02EDTM":"2022-02-12 23:41:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":499,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":34,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":531,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4260,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.01871,"AVALU":"mg/L","BASE2":7.14497,"BASE":8.36052,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.87374,"PCHG2":12.22875,"CHG":-0.34182,"PCHG":-4.08845,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-02 12:20:27","ADY":335,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-319","SUBJID":"id-319","SITEID":"GBR-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":1.83077,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-02","TRTSDTM":"2020-10-02 12:20:27","TRTEDTM":"2022-02-12 23:41:46","TRT01SDTM":"2020-10-02 12:20:27","TRT01EDTM":"2021-02-12 17:41:46","TRT02SDTM":"2021-02-12 17:41:46","TRT02EDTM":"2022-02-12 23:41:46","AP01SDTM":"2020-10-02 12:20:27","AP01EDTM":"2021-02-12 17:41:46","AP02SDTM":"2021-02-12 17:41:46","AP02EDTM":"2022-02-12 23:41:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":499,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":34,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":531,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2248,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.49516,"AVALU":"mg/L","BASE2":7.14497,"BASE":8.36052,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.35019,"PCHG2":32.89299,"CHG":1.13464,"PCHG":13.57136,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-13 12:20:27","ADY":346,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-319","SUBJID":"id-319","SITEID":"GBR-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":1.83077,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-02","TRTSDTM":"2020-10-02 12:20:27","TRTEDTM":"2022-02-12 23:41:46","TRT01SDTM":"2020-10-02 12:20:27","TRT01EDTM":"2021-02-12 17:41:46","TRT02SDTM":"2021-02-12 17:41:46","TRT02EDTM":"2022-02-12 23:41:46","AP01SDTM":"2020-10-02 12:20:27","AP01EDTM":"2021-02-12 17:41:46","AP02SDTM":"2021-02-12 17:41:46","AP02EDTM":"2022-02-12 23:41:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":499,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":34,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":531,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5421,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.81242,"AVALU":"mg/L","BASE2":7.14497,"BASE":8.36052,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.33255,"PCHG2":-4.65427,"CHG":-1.5481,"PCHG":-18.51681,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-09-17 12:20:27","ADY":350,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-319","SUBJID":"id-319","SITEID":"GBR-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":1.83077,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-02","TRTSDTM":"2020-10-02 12:20:27","TRTEDTM":"2022-02-12 23:41:46","TRT01SDTM":"2020-10-02 12:20:27","TRT01EDTM":"2021-02-12 17:41:46","TRT02SDTM":"2021-02-12 17:41:46","TRT02EDTM":"2022-02-12 23:41:46","AP01SDTM":"2020-10-02 12:20:27","AP01EDTM":"2021-02-12 17:41:46","AP02SDTM":"2021-02-12 17:41:46","AP02EDTM":"2022-02-12 23:41:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":499,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":34,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":531,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7295,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.91725,"AVALU":"mg/L","BASE2":7.14497,"BASE":8.36052,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.77229,"PCHG2":24.8047,"CHG":0.55673,"PCHG":6.65905,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-07 12:20:27","ADY":401,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-319","SUBJID":"id-319","SITEID":"GBR-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":1.83077,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-02","TRTSDTM":"2020-10-02 12:20:27","TRTEDTM":"2022-02-12 23:41:46","TRT01SDTM":"2020-10-02 12:20:27","TRT01EDTM":"2021-02-12 17:41:46","TRT02SDTM":"2021-02-12 17:41:46","TRT02EDTM":"2022-02-12 23:41:46","AP01SDTM":"2020-10-02 12:20:27","AP01EDTM":"2021-02-12 17:41:46","AP02SDTM":"2021-02-12 17:41:46","AP02EDTM":"2022-02-12 23:41:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":499,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":34,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":531,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1965,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.1266,"AVALU":"mg/L","BASE2":7.14497,"BASE":8.36052,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.98163,"PCHG2":27.73468,"CHG":0.76608,"PCHG":9.16303,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-16 12:20:27","ADY":410,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-319","SUBJID":"id-319","SITEID":"GBR-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":1.83077,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-02","TRTSDTM":"2020-10-02 12:20:27","TRTEDTM":"2022-02-12 23:41:46","TRT01SDTM":"2020-10-02 12:20:27","TRT01EDTM":"2021-02-12 17:41:46","TRT02SDTM":"2021-02-12 17:41:46","TRT02EDTM":"2022-02-12 23:41:46","AP01SDTM":"2020-10-02 12:20:27","AP01EDTM":"2021-02-12 17:41:46","AP02SDTM":"2021-02-12 17:41:46","AP02EDTM":"2022-02-12 23:41:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":499,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":34,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":531,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6701,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.62548,"AVALU":"g/L","BASE2":2.62548,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-26 12:20:27","ADY":175,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-319","SUBJID":"id-319","SITEID":"GBR-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":1.83077,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-02","TRTSDTM":"2020-10-02 12:20:27","TRTEDTM":"2022-02-12 23:41:46","TRT01SDTM":"2020-10-02 12:20:27","TRT01EDTM":"2021-02-12 17:41:46","TRT02SDTM":"2021-02-12 17:41:46","TRT02EDTM":"2022-02-12 23:41:46","AP01SDTM":"2020-10-02 12:20:27","AP01EDTM":"2021-02-12 17:41:46","AP02SDTM":"2021-02-12 17:41:46","AP02EDTM":"2022-02-12 23:41:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":499,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":34,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":531,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7033,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82247,"AVALU":"g/L","BASE2":2.62548,"BASE":2.82247,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.19699,"PCHG2":7.50289,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-01 12:20:27","ADY":211,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-319","SUBJID":"id-319","SITEID":"GBR-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":1.83077,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-02","TRTSDTM":"2020-10-02 12:20:27","TRTEDTM":"2022-02-12 23:41:46","TRT01SDTM":"2020-10-02 12:20:27","TRT01EDTM":"2021-02-12 17:41:46","TRT02SDTM":"2021-02-12 17:41:46","TRT02EDTM":"2022-02-12 23:41:46","AP01SDTM":"2020-10-02 12:20:27","AP01EDTM":"2021-02-12 17:41:46","AP02SDTM":"2021-02-12 17:41:46","AP02EDTM":"2022-02-12 23:41:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":499,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":34,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":531,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5547,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86875,"AVALU":"g/L","BASE2":2.62548,"BASE":2.82247,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.24327,"PCHG2":9.26575,"CHG":0.04628,"PCHG":1.63983,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-02 12:20:27","ADY":335,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-319","SUBJID":"id-319","SITEID":"GBR-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":1.83077,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-02","TRTSDTM":"2020-10-02 12:20:27","TRTEDTM":"2022-02-12 23:41:46","TRT01SDTM":"2020-10-02 12:20:27","TRT01EDTM":"2021-02-12 17:41:46","TRT02SDTM":"2021-02-12 17:41:46","TRT02EDTM":"2022-02-12 23:41:46","AP01SDTM":"2020-10-02 12:20:27","AP01EDTM":"2021-02-12 17:41:46","AP02SDTM":"2021-02-12 17:41:46","AP02EDTM":"2022-02-12 23:41:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":499,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":34,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":531,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4845,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03901,"AVALU":"g/L","BASE2":2.62548,"BASE":2.82247,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.41353,"PCHG2":15.75077,"CHG":0.21655,"PCHG":7.67224,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-09-13 12:20:27","ADY":346,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-319","SUBJID":"id-319","SITEID":"GBR-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":1.83077,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-02","TRTSDTM":"2020-10-02 12:20:27","TRTEDTM":"2022-02-12 23:41:46","TRT01SDTM":"2020-10-02 12:20:27","TRT01EDTM":"2021-02-12 17:41:46","TRT02SDTM":"2021-02-12 17:41:46","TRT02EDTM":"2022-02-12 23:41:46","AP01SDTM":"2020-10-02 12:20:27","AP01EDTM":"2021-02-12 17:41:46","AP02SDTM":"2021-02-12 17:41:46","AP02EDTM":"2022-02-12 23:41:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":499,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":34,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":531,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7088,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.73162,"AVALU":"g/L","BASE2":2.62548,"BASE":2.82247,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10614,"PCHG2":4.04255,"CHG":-0.09085,"PCHG":-3.21884,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-17 12:20:27","ADY":350,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-319","SUBJID":"id-319","SITEID":"GBR-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":1.83077,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-02","TRTSDTM":"2020-10-02 12:20:27","TRTEDTM":"2022-02-12 23:41:46","TRT01SDTM":"2020-10-02 12:20:27","TRT01EDTM":"2021-02-12 17:41:46","TRT02SDTM":"2021-02-12 17:41:46","TRT02EDTM":"2022-02-12 23:41:46","AP01SDTM":"2020-10-02 12:20:27","AP01EDTM":"2021-02-12 17:41:46","AP02SDTM":"2021-02-12 17:41:46","AP02EDTM":"2022-02-12 23:41:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":499,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":34,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":531,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6031,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8373,"AVALU":"g/L","BASE2":2.62548,"BASE":2.82247,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.21182,"PCHG2":8.06789,"CHG":0.01483,"PCHG":0.52557,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-07 12:20:27","ADY":401,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-319","SUBJID":"id-319","SITEID":"GBR-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":1.83077,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-02","TRTSDTM":"2020-10-02 12:20:27","TRTEDTM":"2022-02-12 23:41:46","TRT01SDTM":"2020-10-02 12:20:27","TRT01EDTM":"2021-02-12 17:41:46","TRT02SDTM":"2021-02-12 17:41:46","TRT02EDTM":"2022-02-12 23:41:46","AP01SDTM":"2020-10-02 12:20:27","AP01EDTM":"2021-02-12 17:41:46","AP02SDTM":"2021-02-12 17:41:46","AP02EDTM":"2022-02-12 23:41:46","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":499,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":34,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":531,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4457,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99391,"AVALU":"g/L","BASE2":2.62548,"BASE":2.82247,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.36843,"PCHG2":14.03302,"CHG":0.17145,"PCHG":6.07437,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-16 12:20:27","ADY":410,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-355","SUBJID":"id-355","SITEID":"GBR-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":10.62796,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-02","TRTSDTM":"2020-04-02 12:54:17","TRTEDTM":"2023-04-03 06:54:17","TRT01SDTM":"2020-04-02 12:54:17","TRT01EDTM":"2022-04-03 00:54:17","TRT02SDTM":"2022-04-03 00:54:17","TRT02EDTM":"2023-04-03 06:54:17","AP01SDTM":"2020-04-02 12:54:17","AP01EDTM":"2022-04-03 00:54:17","AP02SDTM":"2022-04-03 00:54:17","AP02EDTM":"2023-04-03 06:54:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-03","EOSDY":1096,"LSTALVDT":"2023-05-01","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6853,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.40277,"AVALU":"U/L","BASE2":17.40277,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-31 12:54:17","ADY":212,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-355","SUBJID":"id-355","SITEID":"GBR-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":10.62796,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-02","TRTSDTM":"2020-04-02 12:54:17","TRTEDTM":"2023-04-03 06:54:17","TRT01SDTM":"2020-04-02 12:54:17","TRT01EDTM":"2022-04-03 00:54:17","TRT02SDTM":"2022-04-03 00:54:17","TRT02EDTM":"2023-04-03 06:54:17","AP01SDTM":"2020-04-02 12:54:17","AP01EDTM":"2022-04-03 00:54:17","AP02SDTM":"2022-04-03 00:54:17","AP02EDTM":"2023-04-03 06:54:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-03","EOSDY":1096,"LSTALVDT":"2023-05-01","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4828,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.41818,"AVALU":"U/L","BASE2":17.40277,"BASE":25.41818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":8.01542,"PCHG2":46.05829,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-25 12:54:17","ADY":237,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-355","SUBJID":"id-355","SITEID":"GBR-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":10.62796,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-02","TRTSDTM":"2020-04-02 12:54:17","TRTEDTM":"2023-04-03 06:54:17","TRT01SDTM":"2020-04-02 12:54:17","TRT01EDTM":"2022-04-03 00:54:17","TRT02SDTM":"2022-04-03 00:54:17","TRT02EDTM":"2023-04-03 06:54:17","AP01SDTM":"2020-04-02 12:54:17","AP01EDTM":"2022-04-03 00:54:17","AP02SDTM":"2022-04-03 00:54:17","AP02EDTM":"2023-04-03 06:54:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-03","EOSDY":1096,"LSTALVDT":"2023-05-01","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4746,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.19968,"AVALU":"U/L","BASE2":17.40277,"BASE":25.41818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.20309,"PCHG2":-41.3905,"CHG":-15.21851,"PCHG":-59.87253,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-17 12:54:17","ADY":290,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-355","SUBJID":"id-355","SITEID":"GBR-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":10.62796,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-02","TRTSDTM":"2020-04-02 12:54:17","TRTEDTM":"2023-04-03 06:54:17","TRT01SDTM":"2020-04-02 12:54:17","TRT01EDTM":"2022-04-03 00:54:17","TRT02SDTM":"2022-04-03 00:54:17","TRT02EDTM":"2023-04-03 06:54:17","AP01SDTM":"2020-04-02 12:54:17","AP01EDTM":"2022-04-03 00:54:17","AP02SDTM":"2022-04-03 00:54:17","AP02EDTM":"2023-04-03 06:54:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-03","EOSDY":1096,"LSTALVDT":"2023-05-01","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7327,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.47165,"AVALU":"U/L","BASE2":17.40277,"BASE":25.41818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.93112,"PCHG2":-11.0966,"CHG":-9.94653,"PCHG":-39.13156,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-24 12:54:17","ADY":356,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-355","SUBJID":"id-355","SITEID":"GBR-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":10.62796,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-02","TRTSDTM":"2020-04-02 12:54:17","TRTEDTM":"2023-04-03 06:54:17","TRT01SDTM":"2020-04-02 12:54:17","TRT01EDTM":"2022-04-03 00:54:17","TRT02SDTM":"2022-04-03 00:54:17","TRT02EDTM":"2023-04-03 06:54:17","AP01SDTM":"2020-04-02 12:54:17","AP01EDTM":"2022-04-03 00:54:17","AP02SDTM":"2022-04-03 00:54:17","AP02EDTM":"2023-04-03 06:54:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-03","EOSDY":1096,"LSTALVDT":"2023-05-01","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7910,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.39437,"AVALU":"U/L","BASE2":17.40277,"BASE":25.41818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.0084,"PCHG2":-28.77933,"CHG":-13.02382,"PCHG":-51.23819,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-04 12:54:17","ADY":458,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-355","SUBJID":"id-355","SITEID":"GBR-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":10.62796,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-02","TRTSDTM":"2020-04-02 12:54:17","TRTEDTM":"2023-04-03 06:54:17","TRT01SDTM":"2020-04-02 12:54:17","TRT01EDTM":"2022-04-03 00:54:17","TRT02SDTM":"2022-04-03 00:54:17","TRT02EDTM":"2023-04-03 06:54:17","AP01SDTM":"2020-04-02 12:54:17","AP01EDTM":"2022-04-03 00:54:17","AP02SDTM":"2022-04-03 00:54:17","AP02EDTM":"2023-04-03 06:54:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-03","EOSDY":1096,"LSTALVDT":"2023-05-01","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":856,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.44653,"AVALU":"U/L","BASE2":17.40277,"BASE":25.41818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.04376,"PCHG2":34.72873,"CHG":-1.97166,"PCHG":-7.75688,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-26 12:54:17","ADY":784,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-355","SUBJID":"id-355","SITEID":"GBR-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":10.62796,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-02","TRTSDTM":"2020-04-02 12:54:17","TRTEDTM":"2023-04-03 06:54:17","TRT01SDTM":"2020-04-02 12:54:17","TRT01EDTM":"2022-04-03 00:54:17","TRT02SDTM":"2022-04-03 00:54:17","TRT02EDTM":"2023-04-03 06:54:17","AP01SDTM":"2020-04-02 12:54:17","AP01EDTM":"2022-04-03 00:54:17","AP02SDTM":"2022-04-03 00:54:17","AP02EDTM":"2023-04-03 06:54:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-03","EOSDY":1096,"LSTALVDT":"2023-05-01","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7387,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":35.44082,"AVALU":"U/L","BASE2":17.40277,"BASE":25.41818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.03805,"PCHG2":103.65046,"CHG":10.02263,"PCHG":39.43095,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-29 12:54:17","ADY":1001,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-355","SUBJID":"id-355","SITEID":"GBR-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":10.62796,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-02","TRTSDTM":"2020-04-02 12:54:17","TRTEDTM":"2023-04-03 06:54:17","TRT01SDTM":"2020-04-02 12:54:17","TRT01EDTM":"2022-04-03 00:54:17","TRT02SDTM":"2022-04-03 00:54:17","TRT02EDTM":"2023-04-03 06:54:17","AP01SDTM":"2020-04-02 12:54:17","AP01EDTM":"2022-04-03 00:54:17","AP02SDTM":"2022-04-03 00:54:17","AP02EDTM":"2023-04-03 06:54:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-03","EOSDY":1096,"LSTALVDT":"2023-05-01","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8255,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.66969,"AVALU":"mg/L","BASE2":8.66969,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-31 12:54:17","ADY":212,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-355","SUBJID":"id-355","SITEID":"GBR-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":10.62796,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-02","TRTSDTM":"2020-04-02 12:54:17","TRTEDTM":"2023-04-03 06:54:17","TRT01SDTM":"2020-04-02 12:54:17","TRT01EDTM":"2022-04-03 00:54:17","TRT02SDTM":"2022-04-03 00:54:17","TRT02EDTM":"2023-04-03 06:54:17","AP01SDTM":"2020-04-02 12:54:17","AP01EDTM":"2022-04-03 00:54:17","AP02SDTM":"2022-04-03 00:54:17","AP02EDTM":"2023-04-03 06:54:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-03","EOSDY":1096,"LSTALVDT":"2023-05-01","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2620,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.24276,"AVALU":"mg/L","BASE2":8.66969,"BASE":9.24276,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.57308,"PCHG2":6.61015,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-25 12:54:17","ADY":237,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-355","SUBJID":"id-355","SITEID":"GBR-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":10.62796,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-02","TRTSDTM":"2020-04-02 12:54:17","TRTEDTM":"2023-04-03 06:54:17","TRT01SDTM":"2020-04-02 12:54:17","TRT01EDTM":"2022-04-03 00:54:17","TRT02SDTM":"2022-04-03 00:54:17","TRT02EDTM":"2023-04-03 06:54:17","AP01SDTM":"2020-04-02 12:54:17","AP01EDTM":"2022-04-03 00:54:17","AP02SDTM":"2022-04-03 00:54:17","AP02EDTM":"2023-04-03 06:54:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-03","EOSDY":1096,"LSTALVDT":"2023-05-01","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":476,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.88752,"AVALU":"mg/L","BASE2":8.66969,"BASE":9.24276,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.21784,"PCHG2":2.51263,"CHG":-0.35524,"PCHG":-3.84346,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-17 12:54:17","ADY":290,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-355","SUBJID":"id-355","SITEID":"GBR-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":10.62796,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-02","TRTSDTM":"2020-04-02 12:54:17","TRTEDTM":"2023-04-03 06:54:17","TRT01SDTM":"2020-04-02 12:54:17","TRT01EDTM":"2022-04-03 00:54:17","TRT02SDTM":"2022-04-03 00:54:17","TRT02EDTM":"2023-04-03 06:54:17","AP01SDTM":"2020-04-02 12:54:17","AP01EDTM":"2022-04-03 00:54:17","AP02SDTM":"2022-04-03 00:54:17","AP02EDTM":"2023-04-03 06:54:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-03","EOSDY":1096,"LSTALVDT":"2023-05-01","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1467,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.91237,"AVALU":"mg/L","BASE2":8.66969,"BASE":9.24276,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.24269,"PCHG2":2.79924,"CHG":-0.33039,"PCHG":-3.57462,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-24 12:54:17","ADY":356,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-355","SUBJID":"id-355","SITEID":"GBR-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":10.62796,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-02","TRTSDTM":"2020-04-02 12:54:17","TRTEDTM":"2023-04-03 06:54:17","TRT01SDTM":"2020-04-02 12:54:17","TRT01EDTM":"2022-04-03 00:54:17","TRT02SDTM":"2022-04-03 00:54:17","TRT02EDTM":"2023-04-03 06:54:17","AP01SDTM":"2020-04-02 12:54:17","AP01EDTM":"2022-04-03 00:54:17","AP02SDTM":"2022-04-03 00:54:17","AP02EDTM":"2023-04-03 06:54:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-03","EOSDY":1096,"LSTALVDT":"2023-05-01","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4994,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.58726,"AVALU":"mg/L","BASE2":8.66969,"BASE":9.24276,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08242,"PCHG2":-0.95072,"CHG":-0.6555,"PCHG":-7.09207,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-04 12:54:17","ADY":458,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-355","SUBJID":"id-355","SITEID":"GBR-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":10.62796,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-02","TRTSDTM":"2020-04-02 12:54:17","TRTEDTM":"2023-04-03 06:54:17","TRT01SDTM":"2020-04-02 12:54:17","TRT01EDTM":"2022-04-03 00:54:17","TRT02SDTM":"2022-04-03 00:54:17","TRT02EDTM":"2023-04-03 06:54:17","AP01SDTM":"2020-04-02 12:54:17","AP01EDTM":"2022-04-03 00:54:17","AP02SDTM":"2022-04-03 00:54:17","AP02EDTM":"2023-04-03 06:54:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-03","EOSDY":1096,"LSTALVDT":"2023-05-01","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":198,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.8595,"AVALU":"mg/L","BASE2":8.66969,"BASE":9.24276,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.81018,"PCHG2":-9.34502,"CHG":-1.38326,"PCHG":-14.9659,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-05-26 12:54:17","ADY":784,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-355","SUBJID":"id-355","SITEID":"GBR-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":10.62796,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-02","TRTSDTM":"2020-04-02 12:54:17","TRTEDTM":"2023-04-03 06:54:17","TRT01SDTM":"2020-04-02 12:54:17","TRT01EDTM":"2022-04-03 00:54:17","TRT02SDTM":"2022-04-03 00:54:17","TRT02EDTM":"2023-04-03 06:54:17","AP01SDTM":"2020-04-02 12:54:17","AP01EDTM":"2022-04-03 00:54:17","AP02SDTM":"2022-04-03 00:54:17","AP02EDTM":"2023-04-03 06:54:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-03","EOSDY":1096,"LSTALVDT":"2023-05-01","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2711,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.53061,"AVALU":"mg/L","BASE2":8.66969,"BASE":9.24276,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13907,"PCHG2":-1.6041,"CHG":-0.71215,"PCHG":-7.70494,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-29 12:54:17","ADY":1001,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-355","SUBJID":"id-355","SITEID":"GBR-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":10.62796,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-02","TRTSDTM":"2020-04-02 12:54:17","TRTEDTM":"2023-04-03 06:54:17","TRT01SDTM":"2020-04-02 12:54:17","TRT01EDTM":"2022-04-03 00:54:17","TRT02SDTM":"2022-04-03 00:54:17","TRT02EDTM":"2023-04-03 06:54:17","AP01SDTM":"2020-04-02 12:54:17","AP01EDTM":"2022-04-03 00:54:17","AP02SDTM":"2022-04-03 00:54:17","AP02EDTM":"2023-04-03 06:54:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-03","EOSDY":1096,"LSTALVDT":"2023-05-01","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6193,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90679,"AVALU":"g/L","BASE2":2.90679,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-31 12:54:17","ADY":212,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-355","SUBJID":"id-355","SITEID":"GBR-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":10.62796,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-02","TRTSDTM":"2020-04-02 12:54:17","TRTEDTM":"2023-04-03 06:54:17","TRT01SDTM":"2020-04-02 12:54:17","TRT01EDTM":"2022-04-03 00:54:17","TRT02SDTM":"2022-04-03 00:54:17","TRT02EDTM":"2023-04-03 06:54:17","AP01SDTM":"2020-04-02 12:54:17","AP01EDTM":"2022-04-03 00:54:17","AP02SDTM":"2022-04-03 00:54:17","AP02EDTM":"2023-04-03 06:54:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-03","EOSDY":1096,"LSTALVDT":"2023-05-01","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6386,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91947,"AVALU":"g/L","BASE2":2.90679,"BASE":2.91947,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.01268,"PCHG2":0.43619,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-25 12:54:17","ADY":237,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-355","SUBJID":"id-355","SITEID":"GBR-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":10.62796,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-02","TRTSDTM":"2020-04-02 12:54:17","TRTEDTM":"2023-04-03 06:54:17","TRT01SDTM":"2020-04-02 12:54:17","TRT01EDTM":"2022-04-03 00:54:17","TRT02SDTM":"2022-04-03 00:54:17","TRT02EDTM":"2023-04-03 06:54:17","AP01SDTM":"2020-04-02 12:54:17","AP01EDTM":"2022-04-03 00:54:17","AP02SDTM":"2022-04-03 00:54:17","AP02EDTM":"2023-04-03 06:54:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-03","EOSDY":1096,"LSTALVDT":"2023-05-01","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":65,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79289,"AVALU":"g/L","BASE2":2.90679,"BASE":2.91947,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1139,"PCHG2":-3.91843,"CHG":-0.12658,"PCHG":-4.33571,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-17 12:54:17","ADY":290,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-355","SUBJID":"id-355","SITEID":"GBR-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":10.62796,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-02","TRTSDTM":"2020-04-02 12:54:17","TRTEDTM":"2023-04-03 06:54:17","TRT01SDTM":"2020-04-02 12:54:17","TRT01EDTM":"2022-04-03 00:54:17","TRT02SDTM":"2022-04-03 00:54:17","TRT02EDTM":"2023-04-03 06:54:17","AP01SDTM":"2020-04-02 12:54:17","AP01EDTM":"2022-04-03 00:54:17","AP02SDTM":"2022-04-03 00:54:17","AP02EDTM":"2023-04-03 06:54:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-03","EOSDY":1096,"LSTALVDT":"2023-05-01","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7206,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.21685,"AVALU":"g/L","BASE2":2.90679,"BASE":2.91947,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.31006,"PCHG2":10.66686,"CHG":0.29738,"PCHG":10.18623,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2021-03-24 12:54:17","ADY":356,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-355","SUBJID":"id-355","SITEID":"GBR-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":10.62796,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-02","TRTSDTM":"2020-04-02 12:54:17","TRTEDTM":"2023-04-03 06:54:17","TRT01SDTM":"2020-04-02 12:54:17","TRT01EDTM":"2022-04-03 00:54:17","TRT02SDTM":"2022-04-03 00:54:17","TRT02EDTM":"2023-04-03 06:54:17","AP01SDTM":"2020-04-02 12:54:17","AP01EDTM":"2022-04-03 00:54:17","AP02SDTM":"2022-04-03 00:54:17","AP02EDTM":"2023-04-03 06:54:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-03","EOSDY":1096,"LSTALVDT":"2023-05-01","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5223,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76098,"AVALU":"g/L","BASE2":2.90679,"BASE":2.91947,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14581,"PCHG2":-5.01613,"CHG":-0.15849,"PCHG":-5.42864,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-04 12:54:17","ADY":458,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-355","SUBJID":"id-355","SITEID":"GBR-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":10.62796,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-02","TRTSDTM":"2020-04-02 12:54:17","TRTEDTM":"2023-04-03 06:54:17","TRT01SDTM":"2020-04-02 12:54:17","TRT01EDTM":"2022-04-03 00:54:17","TRT02SDTM":"2022-04-03 00:54:17","TRT02EDTM":"2023-04-03 06:54:17","AP01SDTM":"2020-04-02 12:54:17","AP01EDTM":"2022-04-03 00:54:17","AP02SDTM":"2022-04-03 00:54:17","AP02EDTM":"2023-04-03 06:54:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-03","EOSDY":1096,"LSTALVDT":"2023-05-01","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7092,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98194,"AVALU":"g/L","BASE2":2.90679,"BASE":2.91947,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07515,"PCHG2":2.58525,"CHG":0.06247,"PCHG":2.13972,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-26 12:54:17","ADY":784,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-355","SUBJID":"id-355","SITEID":"GBR-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":10.62796,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-02","TRTSDTM":"2020-04-02 12:54:17","TRTEDTM":"2023-04-03 06:54:17","TRT01SDTM":"2020-04-02 12:54:17","TRT01EDTM":"2022-04-03 00:54:17","TRT02SDTM":"2022-04-03 00:54:17","TRT02EDTM":"2023-04-03 06:54:17","AP01SDTM":"2020-04-02 12:54:17","AP01EDTM":"2022-04-03 00:54:17","AP02SDTM":"2022-04-03 00:54:17","AP02EDTM":"2023-04-03 06:54:17","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-03","EOSDY":1096,"LSTALVDT":"2023-05-01","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3777,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97504,"AVALU":"g/L","BASE2":2.90679,"BASE":2.91947,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06825,"PCHG2":2.34789,"CHG":0.05557,"PCHG":1.9034,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-29 12:54:17","ADY":1001,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-384","SUBJID":"id-384","SITEID":"GBR-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":2.644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 06:57:47","TRT01SDTM":"2020-01-19 06:57:47","AP01SDTM":"2020-01-19 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4421,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.41245,"AVALU":"U/L","BASE2":16.41245,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-08 06:57:47","ADY":294,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-384","SUBJID":"id-384","SITEID":"GBR-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":2.644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 06:57:47","TRT01SDTM":"2020-01-19 06:57:47","AP01SDTM":"2020-01-19 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7611,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.47901,"AVALU":"U/L","BASE2":16.41245,"BASE":17.47901,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.06655,"PCHG2":6.49843,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-20 06:57:47","ADY":306,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-384","SUBJID":"id-384","SITEID":"GBR-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":2.644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 06:57:47","TRT01SDTM":"2020-01-19 06:57:47","AP01SDTM":"2020-01-19 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6082,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.15619,"AVALU":"U/L","BASE2":16.41245,"BASE":17.47901,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.74373,"PCHG2":10.62445,"CHG":0.67718,"PCHG":3.87426,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-21 06:57:47","ADY":307,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-384","SUBJID":"id-384","SITEID":"GBR-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":2.644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 06:57:47","TRT01SDTM":"2020-01-19 06:57:47","AP01SDTM":"2020-01-19 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3642,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.31535,"AVALU":"U/L","BASE2":16.41245,"BASE":17.47901,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.90289,"PCHG2":42.05888,"CHG":5.83634,"PCHG":33.39059,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-26 06:57:47","ADY":312,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-384","SUBJID":"id-384","SITEID":"GBR-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":2.644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 06:57:47","TRT01SDTM":"2020-01-19 06:57:47","AP01SDTM":"2020-01-19 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1834,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.6842,"AVALU":"U/L","BASE2":16.41245,"BASE":17.47901,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.27174,"PCHG2":1.65572,"CHG":-0.79481,"PCHG":-4.54721,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-27 06:57:47","ADY":313,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-384","SUBJID":"id-384","SITEID":"GBR-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":2.644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 06:57:47","TRT01SDTM":"2020-01-19 06:57:47","AP01SDTM":"2020-01-19 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1087,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.43425,"AVALU":"U/L","BASE2":16.41245,"BASE":17.47901,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.9782,"PCHG2":-18.146,"CHG":-4.04476,"PCHG":-23.14065,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-14 06:57:47","ADY":542,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-384","SUBJID":"id-384","SITEID":"GBR-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":2.644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 06:57:47","TRT01SDTM":"2020-01-19 06:57:47","AP01SDTM":"2020-01-19 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1685,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.81861,"AVALU":"U/L","BASE2":16.41245,"BASE":17.47901,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.59385,"PCHG2":-9.71119,"CHG":-2.6604,"PCHG":-15.22053,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-30 06:57:47","ADY":558,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-384","SUBJID":"id-384","SITEID":"GBR-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":2.644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 06:57:47","TRT01SDTM":"2020-01-19 06:57:47","AP01SDTM":"2020-01-19 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":251,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.7797,"AVALU":"mg/L","BASE2":9.7797,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-08 06:57:47","ADY":294,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-384","SUBJID":"id-384","SITEID":"GBR-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":2.644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 06:57:47","TRT01SDTM":"2020-01-19 06:57:47","AP01SDTM":"2020-01-19 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7904,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.31586,"AVALU":"mg/L","BASE2":9.7797,"BASE":9.31586,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.46384,"PCHG2":-4.74292,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-20 06:57:47","ADY":306,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-384","SUBJID":"id-384","SITEID":"GBR-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":2.644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 06:57:47","TRT01SDTM":"2020-01-19 06:57:47","AP01SDTM":"2020-01-19 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":382,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.28485,"AVALU":"mg/L","BASE2":9.7797,"BASE":9.31586,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.49485,"PCHG2":-25.51046,"CHG":-2.031,"PCHG":-21.80157,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-11-21 06:57:47","ADY":307,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-384","SUBJID":"id-384","SITEID":"GBR-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":2.644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 06:57:47","TRT01SDTM":"2020-01-19 06:57:47","AP01SDTM":"2020-01-19 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6195,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.06186,"AVALU":"mg/L","BASE2":9.7797,"BASE":9.31586,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.71784,"PCHG2":-7.34008,"CHG":-0.25399,"PCHG":-2.72647,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-26 06:57:47","ADY":312,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-384","SUBJID":"id-384","SITEID":"GBR-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":2.644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 06:57:47","TRT01SDTM":"2020-01-19 06:57:47","AP01SDTM":"2020-01-19 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5263,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.53967,"AVALU":"mg/L","BASE2":9.7797,"BASE":9.31586,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.24003,"PCHG2":-2.45434,"CHG":0.22382,"PCHG":2.40253,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-27 06:57:47","ADY":313,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-384","SUBJID":"id-384","SITEID":"GBR-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":2.644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 06:57:47","TRT01SDTM":"2020-01-19 06:57:47","AP01SDTM":"2020-01-19 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3894,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.62987,"AVALU":"mg/L","BASE2":9.7797,"BASE":9.31586,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.85017,"PCHG2":8.69317,"CHG":1.31401,"PCHG":14.10508,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-07-14 06:57:47","ADY":542,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-384","SUBJID":"id-384","SITEID":"GBR-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":2.644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 06:57:47","TRT01SDTM":"2020-01-19 06:57:47","AP01SDTM":"2020-01-19 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2374,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.75612,"AVALU":"mg/L","BASE2":9.7797,"BASE":9.31586,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.02358,"PCHG2":-10.46636,"CHG":-0.55974,"PCHG":-6.00841,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-30 06:57:47","ADY":558,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-384","SUBJID":"id-384","SITEID":"GBR-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":2.644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 06:57:47","TRT01SDTM":"2020-01-19 06:57:47","AP01SDTM":"2020-01-19 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3043,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78016,"AVALU":"g/L","BASE2":2.78016,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-08 06:57:47","ADY":294,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-384","SUBJID":"id-384","SITEID":"GBR-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":2.644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 06:57:47","TRT01SDTM":"2020-01-19 06:57:47","AP01SDTM":"2020-01-19 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2593,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97012,"AVALU":"g/L","BASE2":2.78016,"BASE":2.97012,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.18997,"PCHG2":6.83294,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-20 06:57:47","ADY":306,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-384","SUBJID":"id-384","SITEID":"GBR-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":2.644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 06:57:47","TRT01SDTM":"2020-01-19 06:57:47","AP01SDTM":"2020-01-19 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5314,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86411,"AVALU":"g/L","BASE2":2.78016,"BASE":2.97012,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08395,"PCHG2":3.0195,"CHG":-0.10602,"PCHG":-3.56953,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-21 06:57:47","ADY":307,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-384","SUBJID":"id-384","SITEID":"GBR-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":2.644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 06:57:47","TRT01SDTM":"2020-01-19 06:57:47","AP01SDTM":"2020-01-19 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1530,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99417,"AVALU":"g/L","BASE2":2.78016,"BASE":2.97012,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.21401,"PCHG2":7.69781,"CHG":0.02404,"PCHG":0.80955,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-26 06:57:47","ADY":312,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-384","SUBJID":"id-384","SITEID":"GBR-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":2.644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 06:57:47","TRT01SDTM":"2020-01-19 06:57:47","AP01SDTM":"2020-01-19 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4106,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92633,"AVALU":"g/L","BASE2":2.78016,"BASE":2.97012,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14617,"PCHG2":5.25769,"CHG":-0.04379,"PCHG":-1.47449,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-27 06:57:47","ADY":313,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-384","SUBJID":"id-384","SITEID":"GBR-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":2.644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 06:57:47","TRT01SDTM":"2020-01-19 06:57:47","AP01SDTM":"2020-01-19 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4313,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76183,"AVALU":"g/L","BASE2":2.78016,"BASE":2.97012,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01833,"PCHG2":-0.65931,"CHG":-0.2083,"PCHG":-7.01305,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-14 06:57:47","ADY":542,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-1-id-384","SUBJID":"id-384","SITEID":"GBR-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-1","INVNAM":"Dr. GBR-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":2.644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-16","TRTSDTM":"2020-01-19 06:57:47","TRT01SDTM":"2020-01-19 06:57:47","AP01SDTM":"2020-01-19 06:57:47","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3246,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02368,"AVALU":"g/L","BASE2":2.78016,"BASE":2.97012,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.24352,"PCHG2":8.75932,"CHG":0.05356,"PCHG":1.80318,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-07-30 06:57:47","ADY":558,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-340","SUBJID":"id-340","SITEID":"GBR-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.11634,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-13","TRTSDTM":"2020-05-17 10:28:18","TRTEDTM":"2022-02-18 20:19:14","TRT01SDTM":"2020-05-17 10:28:18","TRT01EDTM":"2021-02-18 14:19:14","TRT02SDTM":"2021-02-18 14:19:14","TRT02EDTM":"2022-02-18 20:19:14","AP01SDTM":"2020-05-17 10:28:18","AP01EDTM":"2021-02-18 14:19:14","AP02SDTM":"2021-02-18 14:19:14","AP02EDTM":"2022-02-18 20:19:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":643,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-28","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5899,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.95551,"AVALU":"U/L","BASE2":24.95551,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-01 10:28:18","ADY":15,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-340","SUBJID":"id-340","SITEID":"GBR-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.11634,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-13","TRTSDTM":"2020-05-17 10:28:18","TRTEDTM":"2022-02-18 20:19:14","TRT01SDTM":"2020-05-17 10:28:18","TRT01EDTM":"2021-02-18 14:19:14","TRT02SDTM":"2021-02-18 14:19:14","TRT02EDTM":"2022-02-18 20:19:14","AP01SDTM":"2020-05-17 10:28:18","AP01EDTM":"2021-02-18 14:19:14","AP02SDTM":"2021-02-18 14:19:14","AP02EDTM":"2022-02-18 20:19:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":643,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-28","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1236,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.24036,"AVALU":"U/L","BASE2":24.95551,"BASE":19.24036,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-5.71515,"PCHG2":-22.90137,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-26 10:28:18","ADY":101,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-340","SUBJID":"id-340","SITEID":"GBR-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.11634,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-13","TRTSDTM":"2020-05-17 10:28:18","TRTEDTM":"2022-02-18 20:19:14","TRT01SDTM":"2020-05-17 10:28:18","TRT01EDTM":"2021-02-18 14:19:14","TRT02SDTM":"2021-02-18 14:19:14","TRT02EDTM":"2022-02-18 20:19:14","AP01SDTM":"2020-05-17 10:28:18","AP01EDTM":"2021-02-18 14:19:14","AP02SDTM":"2021-02-18 14:19:14","AP02EDTM":"2022-02-18 20:19:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":643,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-28","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6321,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.85783,"AVALU":"U/L","BASE2":24.95551,"BASE":19.24036,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.09767,"PCHG2":-16.41992,"CHG":1.61748,"PCHG":8.4067,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-21 10:28:18","ADY":280,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-340","SUBJID":"id-340","SITEID":"GBR-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.11634,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-13","TRTSDTM":"2020-05-17 10:28:18","TRTEDTM":"2022-02-18 20:19:14","TRT01SDTM":"2020-05-17 10:28:18","TRT01EDTM":"2021-02-18 14:19:14","TRT02SDTM":"2021-02-18 14:19:14","TRT02EDTM":"2022-02-18 20:19:14","AP01SDTM":"2020-05-17 10:28:18","AP01EDTM":"2021-02-18 14:19:14","AP02SDTM":"2021-02-18 14:19:14","AP02EDTM":"2022-02-18 20:19:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":643,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-28","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3184,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":35.23397,"AVALU":"U/L","BASE2":24.95551,"BASE":19.24036,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.27846,"PCHG2":41.18713,"CHG":15.99361,"PCHG":83.12533,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-11 10:28:18","ADY":359,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-340","SUBJID":"id-340","SITEID":"GBR-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.11634,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-13","TRTSDTM":"2020-05-17 10:28:18","TRTEDTM":"2022-02-18 20:19:14","TRT01SDTM":"2020-05-17 10:28:18","TRT01EDTM":"2021-02-18 14:19:14","TRT02SDTM":"2021-02-18 14:19:14","TRT02EDTM":"2022-02-18 20:19:14","AP01SDTM":"2020-05-17 10:28:18","AP01EDTM":"2021-02-18 14:19:14","AP02SDTM":"2021-02-18 14:19:14","AP02EDTM":"2022-02-18 20:19:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":643,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-28","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":663,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.35818,"AVALU":"U/L","BASE2":24.95551,"BASE":19.24036,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-22.59733,"PCHG2":-90.55047,"CHG":-16.88218,"PCHG":-87.74358,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-08-26 10:28:18","ADY":466,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-340","SUBJID":"id-340","SITEID":"GBR-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.11634,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-13","TRTSDTM":"2020-05-17 10:28:18","TRTEDTM":"2022-02-18 20:19:14","TRT01SDTM":"2020-05-17 10:28:18","TRT01EDTM":"2021-02-18 14:19:14","TRT02SDTM":"2021-02-18 14:19:14","TRT02EDTM":"2022-02-18 20:19:14","AP01SDTM":"2020-05-17 10:28:18","AP01EDTM":"2021-02-18 14:19:14","AP02SDTM":"2021-02-18 14:19:14","AP02EDTM":"2022-02-18 20:19:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":643,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-28","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6448,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.25571,"AVALU":"U/L","BASE2":24.95551,"BASE":19.24036,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.6998,"PCHG2":-30.85411,"CHG":-1.98465,"PCHG":-10.31502,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-12 10:28:18","ADY":544,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-340","SUBJID":"id-340","SITEID":"GBR-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.11634,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-13","TRTSDTM":"2020-05-17 10:28:18","TRTEDTM":"2022-02-18 20:19:14","TRT01SDTM":"2020-05-17 10:28:18","TRT01EDTM":"2021-02-18 14:19:14","TRT02SDTM":"2021-02-18 14:19:14","TRT02EDTM":"2022-02-18 20:19:14","AP01SDTM":"2020-05-17 10:28:18","AP01EDTM":"2021-02-18 14:19:14","AP02SDTM":"2021-02-18 14:19:14","AP02EDTM":"2022-02-18 20:19:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":643,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-28","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1017,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.28634,"AVALU":"U/L","BASE2":24.95551,"BASE":19.24036,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.33083,"PCHG2":13.34709,"CHG":9.04599,"PCHG":47.0157,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-21 10:28:18","ADY":553,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-340","SUBJID":"id-340","SITEID":"GBR-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.11634,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-13","TRTSDTM":"2020-05-17 10:28:18","TRTEDTM":"2022-02-18 20:19:14","TRT01SDTM":"2020-05-17 10:28:18","TRT01EDTM":"2021-02-18 14:19:14","TRT02SDTM":"2021-02-18 14:19:14","TRT02EDTM":"2022-02-18 20:19:14","AP01SDTM":"2020-05-17 10:28:18","AP01EDTM":"2021-02-18 14:19:14","AP02SDTM":"2021-02-18 14:19:14","AP02EDTM":"2022-02-18 20:19:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":643,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-28","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5927,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.46877,"AVALU":"mg/L","BASE2":7.46877,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-2","ADTM":"2020-06-01 10:28:18","ADY":15,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-340","SUBJID":"id-340","SITEID":"GBR-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.11634,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-13","TRTSDTM":"2020-05-17 10:28:18","TRTEDTM":"2022-02-18 20:19:14","TRT01SDTM":"2020-05-17 10:28:18","TRT01EDTM":"2021-02-18 14:19:14","TRT02SDTM":"2021-02-18 14:19:14","TRT02EDTM":"2022-02-18 20:19:14","AP01SDTM":"2020-05-17 10:28:18","AP01EDTM":"2021-02-18 14:19:14","AP02SDTM":"2021-02-18 14:19:14","AP02EDTM":"2022-02-18 20:19:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":643,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-28","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7709,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.71543,"AVALU":"mg/L","BASE2":7.46877,"BASE":7.71543,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.24666,"PCHG2":3.30254,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2020-08-26 10:28:18","ADY":101,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-340","SUBJID":"id-340","SITEID":"GBR-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.11634,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-13","TRTSDTM":"2020-05-17 10:28:18","TRTEDTM":"2022-02-18 20:19:14","TRT01SDTM":"2020-05-17 10:28:18","TRT01EDTM":"2021-02-18 14:19:14","TRT02SDTM":"2021-02-18 14:19:14","TRT02EDTM":"2022-02-18 20:19:14","AP01SDTM":"2020-05-17 10:28:18","AP01EDTM":"2021-02-18 14:19:14","AP02SDTM":"2021-02-18 14:19:14","AP02EDTM":"2022-02-18 20:19:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":643,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-28","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7785,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.66617,"AVALU":"mg/L","BASE2":7.46877,"BASE":7.71543,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.1974,"PCHG2":29.42111,"CHG":1.95074,"PCHG":25.28357,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-02-21 10:28:18","ADY":280,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-340","SUBJID":"id-340","SITEID":"GBR-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.11634,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-13","TRTSDTM":"2020-05-17 10:28:18","TRTEDTM":"2022-02-18 20:19:14","TRT01SDTM":"2020-05-17 10:28:18","TRT01EDTM":"2021-02-18 14:19:14","TRT02SDTM":"2021-02-18 14:19:14","TRT02EDTM":"2022-02-18 20:19:14","AP01SDTM":"2020-05-17 10:28:18","AP01EDTM":"2021-02-18 14:19:14","AP02SDTM":"2021-02-18 14:19:14","AP02EDTM":"2022-02-18 20:19:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":643,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-28","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":79,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.46144,"AVALU":"mg/L","BASE2":7.46877,"BASE":7.71543,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.99267,"PCHG2":13.29088,"CHG":0.74601,"PCHG":9.66902,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-05-11 10:28:18","ADY":359,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-340","SUBJID":"id-340","SITEID":"GBR-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.11634,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-13","TRTSDTM":"2020-05-17 10:28:18","TRTEDTM":"2022-02-18 20:19:14","TRT01SDTM":"2020-05-17 10:28:18","TRT01EDTM":"2021-02-18 14:19:14","TRT02SDTM":"2021-02-18 14:19:14","TRT02EDTM":"2022-02-18 20:19:14","AP01SDTM":"2020-05-17 10:28:18","AP01EDTM":"2021-02-18 14:19:14","AP02SDTM":"2021-02-18 14:19:14","AP02EDTM":"2022-02-18 20:19:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":643,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-28","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2256,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.69052,"AVALU":"mg/L","BASE2":7.46877,"BASE":7.71543,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.22174,"PCHG2":2.96893,"CHG":-0.02492,"PCHG":-0.32294,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-2","ADTM":"2021-08-26 10:28:18","ADY":466,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-340","SUBJID":"id-340","SITEID":"GBR-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.11634,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-13","TRTSDTM":"2020-05-17 10:28:18","TRTEDTM":"2022-02-18 20:19:14","TRT01SDTM":"2020-05-17 10:28:18","TRT01EDTM":"2021-02-18 14:19:14","TRT02SDTM":"2021-02-18 14:19:14","TRT02EDTM":"2022-02-18 20:19:14","AP01SDTM":"2020-05-17 10:28:18","AP01EDTM":"2021-02-18 14:19:14","AP02SDTM":"2021-02-18 14:19:14","AP02EDTM":"2022-02-18 20:19:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":643,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-28","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1656,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.8028,"AVALU":"mg/L","BASE2":7.46877,"BASE":7.71543,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.33403,"PCHG2":31.25045,"CHG":2.08737,"PCHG":27.05443,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-11-12 10:28:18","ADY":544,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-340","SUBJID":"id-340","SITEID":"GBR-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.11634,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-13","TRTSDTM":"2020-05-17 10:28:18","TRTEDTM":"2022-02-18 20:19:14","TRT01SDTM":"2020-05-17 10:28:18","TRT01EDTM":"2021-02-18 14:19:14","TRT02SDTM":"2021-02-18 14:19:14","TRT02EDTM":"2022-02-18 20:19:14","AP01SDTM":"2020-05-17 10:28:18","AP01EDTM":"2021-02-18 14:19:14","AP02SDTM":"2021-02-18 14:19:14","AP02EDTM":"2022-02-18 20:19:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":643,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-28","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7652,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.53176,"AVALU":"mg/L","BASE2":7.46877,"BASE":7.71543,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.06298,"PCHG2":27.62145,"CHG":1.81632,"PCHG":23.54145,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-11-21 10:28:18","ADY":553,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-340","SUBJID":"id-340","SITEID":"GBR-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.11634,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-13","TRTSDTM":"2020-05-17 10:28:18","TRTEDTM":"2022-02-18 20:19:14","TRT01SDTM":"2020-05-17 10:28:18","TRT01EDTM":"2021-02-18 14:19:14","TRT02SDTM":"2021-02-18 14:19:14","TRT02EDTM":"2022-02-18 20:19:14","AP01SDTM":"2020-05-17 10:28:18","AP01EDTM":"2021-02-18 14:19:14","AP02SDTM":"2021-02-18 14:19:14","AP02EDTM":"2022-02-18 20:19:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":643,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-28","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7682,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8527,"AVALU":"g/L","BASE2":2.8527,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-01 10:28:18","ADY":15,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-340","SUBJID":"id-340","SITEID":"GBR-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.11634,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-13","TRTSDTM":"2020-05-17 10:28:18","TRTEDTM":"2022-02-18 20:19:14","TRT01SDTM":"2020-05-17 10:28:18","TRT01EDTM":"2021-02-18 14:19:14","TRT02SDTM":"2021-02-18 14:19:14","TRT02EDTM":"2022-02-18 20:19:14","AP01SDTM":"2020-05-17 10:28:18","AP01EDTM":"2021-02-18 14:19:14","AP02SDTM":"2021-02-18 14:19:14","AP02EDTM":"2022-02-18 20:19:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":643,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-28","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8090,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96522,"AVALU":"g/L","BASE2":2.8527,"BASE":2.96522,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.11253,"PCHG2":3.94452,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-26 10:28:18","ADY":101,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-340","SUBJID":"id-340","SITEID":"GBR-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.11634,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-13","TRTSDTM":"2020-05-17 10:28:18","TRTEDTM":"2022-02-18 20:19:14","TRT01SDTM":"2020-05-17 10:28:18","TRT01EDTM":"2021-02-18 14:19:14","TRT02SDTM":"2021-02-18 14:19:14","TRT02EDTM":"2022-02-18 20:19:14","AP01SDTM":"2020-05-17 10:28:18","AP01EDTM":"2021-02-18 14:19:14","AP02SDTM":"2021-02-18 14:19:14","AP02EDTM":"2022-02-18 20:19:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":643,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-28","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7212,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89337,"AVALU":"g/L","BASE2":2.8527,"BASE":2.96522,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04067,"PCHG2":1.42575,"CHG":-0.07185,"PCHG":-2.42319,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-21 10:28:18","ADY":280,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-340","SUBJID":"id-340","SITEID":"GBR-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.11634,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-13","TRTSDTM":"2020-05-17 10:28:18","TRTEDTM":"2022-02-18 20:19:14","TRT01SDTM":"2020-05-17 10:28:18","TRT01EDTM":"2021-02-18 14:19:14","TRT02SDTM":"2021-02-18 14:19:14","TRT02EDTM":"2022-02-18 20:19:14","AP01SDTM":"2020-05-17 10:28:18","AP01EDTM":"2021-02-18 14:19:14","AP02SDTM":"2021-02-18 14:19:14","AP02EDTM":"2022-02-18 20:19:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":643,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-28","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1827,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86307,"AVALU":"g/L","BASE2":2.8527,"BASE":2.96522,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01037,"PCHG2":0.36341,"CHG":-0.10216,"PCHG":-3.44521,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-11 10:28:18","ADY":359,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-340","SUBJID":"id-340","SITEID":"GBR-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.11634,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-13","TRTSDTM":"2020-05-17 10:28:18","TRTEDTM":"2022-02-18 20:19:14","TRT01SDTM":"2020-05-17 10:28:18","TRT01EDTM":"2021-02-18 14:19:14","TRT02SDTM":"2021-02-18 14:19:14","TRT02EDTM":"2022-02-18 20:19:14","AP01SDTM":"2020-05-17 10:28:18","AP01EDTM":"2021-02-18 14:19:14","AP02SDTM":"2021-02-18 14:19:14","AP02EDTM":"2022-02-18 20:19:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":643,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-28","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7786,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.19629,"AVALU":"g/L","BASE2":2.8527,"BASE":2.96522,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.34359,"PCHG2":12.04446,"CHG":0.23107,"PCHG":7.79255,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-08-26 10:28:18","ADY":466,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-340","SUBJID":"id-340","SITEID":"GBR-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.11634,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-13","TRTSDTM":"2020-05-17 10:28:18","TRTEDTM":"2022-02-18 20:19:14","TRT01SDTM":"2020-05-17 10:28:18","TRT01EDTM":"2021-02-18 14:19:14","TRT02SDTM":"2021-02-18 14:19:14","TRT02EDTM":"2022-02-18 20:19:14","AP01SDTM":"2020-05-17 10:28:18","AP01EDTM":"2021-02-18 14:19:14","AP02SDTM":"2021-02-18 14:19:14","AP02EDTM":"2022-02-18 20:19:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":643,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-28","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5234,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.07772,"AVALU":"g/L","BASE2":2.8527,"BASE":2.96522,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.22502,"PCHG2":7.88797,"CHG":0.11249,"PCHG":3.7938,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-11-12 10:28:18","ADY":544,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-340","SUBJID":"id-340","SITEID":"GBR-11","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.11634,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-13","TRTSDTM":"2020-05-17 10:28:18","TRTEDTM":"2022-02-18 20:19:14","TRT01SDTM":"2020-05-17 10:28:18","TRT01EDTM":"2021-02-18 14:19:14","TRT02SDTM":"2021-02-18 14:19:14","TRT02EDTM":"2022-02-18 20:19:14","AP01SDTM":"2020-05-17 10:28:18","AP01EDTM":"2021-02-18 14:19:14","AP02SDTM":"2021-02-18 14:19:14","AP02EDTM":"2022-02-18 20:19:14","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":643,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-28","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1964,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01982,"AVALU":"g/L","BASE2":2.8527,"BASE":2.96522,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16712,"PCHG2":5.85843,"CHG":0.0546,"PCHG":1.84127,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-11-21 10:28:18","ADY":553,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-390","SUBJID":"id-390","SITEID":"GBR-11","AGE":69,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":2.05012,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 19:28:12","TRT01SDTM":"2019-12-31 19:28:12","AP01SDTM":"2019-12-31 19:28:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5957,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":40.06102,"AVALU":"U/L","BASE2":40.06102,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-05 19:28:12","ADY":126,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-390","SUBJID":"id-390","SITEID":"GBR-11","AGE":69,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":2.05012,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 19:28:12","TRT01SDTM":"2019-12-31 19:28:12","AP01SDTM":"2019-12-31 19:28:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":718,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.44367,"AVALU":"U/L","BASE2":40.06102,"BASE":11.44367,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-28.61735,"PCHG2":-71.4344,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-23 19:28:12","ADY":205,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-390","SUBJID":"id-390","SITEID":"GBR-11","AGE":69,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":2.05012,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 19:28:12","TRT01SDTM":"2019-12-31 19:28:12","AP01SDTM":"2019-12-31 19:28:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":693,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.38663,"AVALU":"U/L","BASE2":40.06102,"BASE":11.44367,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-27.67439,"PCHG2":-69.08058,"CHG":0.94296,"PCHG":8.24002,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-12 19:28:12","ADY":225,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-390","SUBJID":"id-390","SITEID":"GBR-11","AGE":69,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":2.05012,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 19:28:12","TRT01SDTM":"2019-12-31 19:28:12","AP01SDTM":"2019-12-31 19:28:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5753,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.8495,"AVALU":"U/L","BASE2":40.06102,"BASE":11.44367,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-33.21152,"PCHG2":-82.90233,"CHG":-4.59417,"PCHG":-40.14597,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-10-11 19:28:12","ADY":285,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-390","SUBJID":"id-390","SITEID":"GBR-11","AGE":69,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":2.05012,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 19:28:12","TRT01SDTM":"2019-12-31 19:28:12","AP01SDTM":"2019-12-31 19:28:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7533,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.71335,"AVALU":"U/L","BASE2":40.06102,"BASE":11.44367,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-39.34767,"PCHG2":-98.21934,"CHG":-10.73032,"PCHG":-93.76642,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-11-27 19:28:12","ADY":332,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-390","SUBJID":"id-390","SITEID":"GBR-11","AGE":69,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":2.05012,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 19:28:12","TRT01SDTM":"2019-12-31 19:28:12","AP01SDTM":"2019-12-31 19:28:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":860,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.29139,"AVALU":"U/L","BASE2":40.06102,"BASE":11.44367,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-35.76964,"PCHG2":-89.28787,"CHG":-7.15229,"PCHG":-62.49991,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-02-08 19:28:12","ADY":405,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-390","SUBJID":"id-390","SITEID":"GBR-11","AGE":69,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":2.05012,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 19:28:12","TRT01SDTM":"2019-12-31 19:28:12","AP01SDTM":"2019-12-31 19:28:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7784,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.9126,"AVALU":"U/L","BASE2":40.06102,"BASE":11.44367,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-28.14843,"PCHG2":-70.26387,"CHG":0.46892,"PCHG":4.09768,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-28 19:28:12","ADY":637,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-390","SUBJID":"id-390","SITEID":"GBR-11","AGE":69,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":2.05012,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 19:28:12","TRT01SDTM":"2019-12-31 19:28:12","AP01SDTM":"2019-12-31 19:28:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3318,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.40077,"AVALU":"mg/L","BASE2":8.40077,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-05-05 19:28:12","ADY":126,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-390","SUBJID":"id-390","SITEID":"GBR-11","AGE":69,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":2.05012,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 19:28:12","TRT01SDTM":"2019-12-31 19:28:12","AP01SDTM":"2019-12-31 19:28:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2513,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.35649,"AVALU":"mg/L","BASE2":8.40077,"BASE":10.35649,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.95571,"PCHG2":23.28014,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-07-23 19:28:12","ADY":205,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-390","SUBJID":"id-390","SITEID":"GBR-11","AGE":69,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":2.05012,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 19:28:12","TRT01SDTM":"2019-12-31 19:28:12","AP01SDTM":"2019-12-31 19:28:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1328,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.15229,"AVALU":"mg/L","BASE2":8.40077,"BASE":10.35649,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.24848,"PCHG2":-2.95785,"CHG":-2.20419,"PCHG":-21.28323,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-08-12 19:28:12","ADY":225,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-390","SUBJID":"id-390","SITEID":"GBR-11","AGE":69,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":2.05012,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 19:28:12","TRT01SDTM":"2019-12-31 19:28:12","AP01SDTM":"2019-12-31 19:28:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7022,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.5826,"AVALU":"mg/L","BASE2":8.40077,"BASE":10.35649,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.18183,"PCHG2":14.06808,"CHG":-0.77388,"PCHG":-7.47246,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-10-11 19:28:12","ADY":285,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-390","SUBJID":"id-390","SITEID":"GBR-11","AGE":69,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":2.05012,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 19:28:12","TRT01SDTM":"2019-12-31 19:28:12","AP01SDTM":"2019-12-31 19:28:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5509,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.98773,"AVALU":"mg/L","BASE2":8.40077,"BASE":10.35649,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.41305,"PCHG2":-4.91678,"CHG":-2.36876,"PCHG":-22.87223,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-1","BTOXGR":"1","ADTM":"2020-11-27 19:28:12","ADY":332,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-390","SUBJID":"id-390","SITEID":"GBR-11","AGE":69,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":2.05012,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 19:28:12","TRT01SDTM":"2019-12-31 19:28:12","AP01SDTM":"2019-12-31 19:28:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4492,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.03225,"AVALU":"mg/L","BASE2":8.40077,"BASE":10.35649,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.63147,"PCHG2":7.51683,"CHG":-1.32424,"PCHG":-12.78658,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-02-08 19:28:12","ADY":405,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-390","SUBJID":"id-390","SITEID":"GBR-11","AGE":69,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":2.05012,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 19:28:12","TRT01SDTM":"2019-12-31 19:28:12","AP01SDTM":"2019-12-31 19:28:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1585,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.1169,"AVALU":"mg/L","BASE2":8.40077,"BASE":10.35649,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.71613,"PCHG2":8.52455,"CHG":-1.23958,"PCHG":-11.96915,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-09-28 19:28:12","ADY":637,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-390","SUBJID":"id-390","SITEID":"GBR-11","AGE":69,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":2.05012,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 19:28:12","TRT01SDTM":"2019-12-31 19:28:12","AP01SDTM":"2019-12-31 19:28:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2672,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03698,"AVALU":"g/L","BASE2":3.03698,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-05-05 19:28:12","ADY":126,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-390","SUBJID":"id-390","SITEID":"GBR-11","AGE":69,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":2.05012,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 19:28:12","TRT01SDTM":"2019-12-31 19:28:12","AP01SDTM":"2019-12-31 19:28:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4826,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77482,"AVALU":"g/L","BASE2":3.03698,"BASE":2.77482,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.26215,"PCHG2":-8.63206,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-23 19:28:12","ADY":205,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-390","SUBJID":"id-390","SITEID":"GBR-11","AGE":69,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":2.05012,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 19:28:12","TRT01SDTM":"2019-12-31 19:28:12","AP01SDTM":"2019-12-31 19:28:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6078,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92999,"AVALU":"g/L","BASE2":3.03698,"BASE":2.77482,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10699,"PCHG2":-3.52281,"CHG":0.15517,"PCHG":5.59195,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-12 19:28:12","ADY":225,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-390","SUBJID":"id-390","SITEID":"GBR-11","AGE":69,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":2.05012,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 19:28:12","TRT01SDTM":"2019-12-31 19:28:12","AP01SDTM":"2019-12-31 19:28:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":340,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95327,"AVALU":"g/L","BASE2":3.03698,"BASE":2.77482,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08371,"PCHG2":-2.75626,"CHG":0.17845,"PCHG":6.43092,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-11 19:28:12","ADY":285,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-390","SUBJID":"id-390","SITEID":"GBR-11","AGE":69,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":2.05012,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 19:28:12","TRT01SDTM":"2019-12-31 19:28:12","AP01SDTM":"2019-12-31 19:28:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4090,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7178,"AVALU":"g/L","BASE2":3.03698,"BASE":2.77482,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.31918,"PCHG2":-10.50977,"CHG":-0.05703,"PCHG":-2.05511,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-27 19:28:12","ADY":332,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-390","SUBJID":"id-390","SITEID":"GBR-11","AGE":69,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":2.05012,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 19:28:12","TRT01SDTM":"2019-12-31 19:28:12","AP01SDTM":"2019-12-31 19:28:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1290,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86954,"AVALU":"g/L","BASE2":3.03698,"BASE":2.77482,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16743,"PCHG2":-5.51319,"CHG":0.09472,"PCHG":3.41353,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-08 19:28:12","ADY":405,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-11-id-390","SUBJID":"id-390","SITEID":"GBR-11","AGE":69,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-11","INVNAM":"Dr. GBR-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":2.05012,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-27","TRTSDTM":"2019-12-31 19:28:12","TRT01SDTM":"2019-12-31 19:28:12","AP01SDTM":"2019-12-31 19:28:12","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1300,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8708,"AVALU":"g/L","BASE2":3.03698,"BASE":2.77482,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16618,"PCHG2":-5.47189,"CHG":0.09597,"PCHG":3.45873,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-28 19:28:12","ADY":637,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-13-id-80","SUBJID":"id-80","SITEID":"GBR-13","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-13","INVNAM":"Dr. GBR-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":7.74987,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 19:46:20","TRTEDTM":"2023-10-25 13:46:20","TRT01SDTM":"2020-10-24 19:46:20","TRT01EDTM":"2022-10-25 07:46:20","TRT02SDTM":"2022-10-25 07:46:20","TRT02EDTM":"2023-10-25 13:46:20","AP01SDTM":"2020-10-24 19:46:20","AP01EDTM":"2022-10-25 07:46:20","AP02SDTM":"2022-10-25 07:46:20","AP02EDTM":"2023-10-25 13:46:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-25","EOSDY":1096,"LSTALVDT":"2023-11-14","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3441,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.65719,"AVALU":"U/L","BASE2":14.65719,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-30 19:46:20","ADY":37,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-13-id-80","SUBJID":"id-80","SITEID":"GBR-13","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-13","INVNAM":"Dr. GBR-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":7.74987,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 19:46:20","TRTEDTM":"2023-10-25 13:46:20","TRT01SDTM":"2020-10-24 19:46:20","TRT01EDTM":"2022-10-25 07:46:20","TRT02SDTM":"2022-10-25 07:46:20","TRT02EDTM":"2023-10-25 13:46:20","AP01SDTM":"2020-10-24 19:46:20","AP01EDTM":"2022-10-25 07:46:20","AP02SDTM":"2022-10-25 07:46:20","AP02EDTM":"2023-10-25 13:46:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-25","EOSDY":1096,"LSTALVDT":"2023-11-14","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":816,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.12,"AVALU":"U/L","BASE2":14.65719,"BASE":31.12,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":16.46281,"PCHG2":112.31907,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-31 19:46:20","ADY":68,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-13-id-80","SUBJID":"id-80","SITEID":"GBR-13","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-13","INVNAM":"Dr. GBR-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":7.74987,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 19:46:20","TRTEDTM":"2023-10-25 13:46:20","TRT01SDTM":"2020-10-24 19:46:20","TRT01EDTM":"2022-10-25 07:46:20","TRT02SDTM":"2022-10-25 07:46:20","TRT02EDTM":"2023-10-25 13:46:20","AP01SDTM":"2020-10-24 19:46:20","AP01EDTM":"2022-10-25 07:46:20","AP02SDTM":"2022-10-25 07:46:20","AP02EDTM":"2023-10-25 13:46:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-25","EOSDY":1096,"LSTALVDT":"2023-11-14","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6974,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.94875,"AVALU":"U/L","BASE2":14.65719,"BASE":31.12,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.29156,"PCHG2":22.45697,"CHG":-13.17125,"PCHG":-42.32408,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-26 19:46:20","ADY":245,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-13-id-80","SUBJID":"id-80","SITEID":"GBR-13","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-13","INVNAM":"Dr. GBR-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":7.74987,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 19:46:20","TRTEDTM":"2023-10-25 13:46:20","TRT01SDTM":"2020-10-24 19:46:20","TRT01EDTM":"2022-10-25 07:46:20","TRT02SDTM":"2022-10-25 07:46:20","TRT02EDTM":"2023-10-25 13:46:20","AP01SDTM":"2020-10-24 19:46:20","AP01EDTM":"2022-10-25 07:46:20","AP02SDTM":"2022-10-25 07:46:20","AP02EDTM":"2023-10-25 13:46:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-25","EOSDY":1096,"LSTALVDT":"2023-11-14","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7909,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.93881,"AVALU":"U/L","BASE2":14.65719,"BASE":31.12,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.71838,"PCHG2":-73.1271,"CHG":-27.18119,"PCHG":-87.34315,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2022-06-27 19:46:20","ADY":611,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-13-id-80","SUBJID":"id-80","SITEID":"GBR-13","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-13","INVNAM":"Dr. GBR-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":7.74987,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 19:46:20","TRTEDTM":"2023-10-25 13:46:20","TRT01SDTM":"2020-10-24 19:46:20","TRT01EDTM":"2022-10-25 07:46:20","TRT02SDTM":"2022-10-25 07:46:20","TRT02EDTM":"2023-10-25 13:46:20","AP01SDTM":"2020-10-24 19:46:20","AP01EDTM":"2022-10-25 07:46:20","AP02SDTM":"2022-10-25 07:46:20","AP02EDTM":"2023-10-25 13:46:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-25","EOSDY":1096,"LSTALVDT":"2023-11-14","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5708,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.7136,"AVALU":"U/L","BASE2":14.65719,"BASE":31.12,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.05642,"PCHG2":14.03009,"CHG":-14.4064,"PCHG":-46.29305,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-28 19:46:20","ADY":916,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-13-id-80","SUBJID":"id-80","SITEID":"GBR-13","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-13","INVNAM":"Dr. GBR-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":7.74987,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 19:46:20","TRTEDTM":"2023-10-25 13:46:20","TRT01SDTM":"2020-10-24 19:46:20","TRT01EDTM":"2022-10-25 07:46:20","TRT02SDTM":"2022-10-25 07:46:20","TRT02EDTM":"2023-10-25 13:46:20","AP01SDTM":"2020-10-24 19:46:20","AP01EDTM":"2022-10-25 07:46:20","AP02SDTM":"2022-10-25 07:46:20","AP02EDTM":"2023-10-25 13:46:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-25","EOSDY":1096,"LSTALVDT":"2023-11-14","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4684,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.92445,"AVALU":"U/L","BASE2":14.65719,"BASE":31.12,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.73273,"PCHG2":-11.82174,"CHG":-18.19555,"PCHG":-58.46898,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-09 19:46:20","ADY":1019,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-13-id-80","SUBJID":"id-80","SITEID":"GBR-13","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-13","INVNAM":"Dr. GBR-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":7.74987,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 19:46:20","TRTEDTM":"2023-10-25 13:46:20","TRT01SDTM":"2020-10-24 19:46:20","TRT01EDTM":"2022-10-25 07:46:20","TRT02SDTM":"2022-10-25 07:46:20","TRT02EDTM":"2023-10-25 13:46:20","AP01SDTM":"2020-10-24 19:46:20","AP01EDTM":"2022-10-25 07:46:20","AP02SDTM":"2022-10-25 07:46:20","AP02EDTM":"2023-10-25 13:46:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-25","EOSDY":1096,"LSTALVDT":"2023-11-14","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5123,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.34207,"AVALU":"U/L","BASE2":14.65719,"BASE":31.12,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.68488,"PCHG2":93.36637,"CHG":-2.77793,"PCHG":-8.92652,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-30 19:46:20","ADY":1040,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-13-id-80","SUBJID":"id-80","SITEID":"GBR-13","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-13","INVNAM":"Dr. GBR-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":7.74987,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 19:46:20","TRTEDTM":"2023-10-25 13:46:20","TRT01SDTM":"2020-10-24 19:46:20","TRT01EDTM":"2022-10-25 07:46:20","TRT02SDTM":"2022-10-25 07:46:20","TRT02EDTM":"2023-10-25 13:46:20","AP01SDTM":"2020-10-24 19:46:20","AP01EDTM":"2022-10-25 07:46:20","AP02SDTM":"2022-10-25 07:46:20","AP02EDTM":"2023-10-25 13:46:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-25","EOSDY":1096,"LSTALVDT":"2023-11-14","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7937,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.89705,"AVALU":"mg/L","BASE2":7.89705,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-11-30 19:46:20","ADY":37,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-13-id-80","SUBJID":"id-80","SITEID":"GBR-13","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-13","INVNAM":"Dr. GBR-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":7.74987,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 19:46:20","TRTEDTM":"2023-10-25 13:46:20","TRT01SDTM":"2020-10-24 19:46:20","TRT01EDTM":"2022-10-25 07:46:20","TRT02SDTM":"2022-10-25 07:46:20","TRT02EDTM":"2023-10-25 13:46:20","AP01SDTM":"2020-10-24 19:46:20","AP01EDTM":"2022-10-25 07:46:20","AP02SDTM":"2022-10-25 07:46:20","AP02EDTM":"2023-10-25 13:46:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-25","EOSDY":1096,"LSTALVDT":"2023-11-14","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3075,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.26519,"AVALU":"mg/L","BASE2":7.89705,"BASE":8.26519,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.36814,"PCHG2":4.66168,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-31 19:46:20","ADY":68,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-13-id-80","SUBJID":"id-80","SITEID":"GBR-13","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-13","INVNAM":"Dr. GBR-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":7.74987,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 19:46:20","TRTEDTM":"2023-10-25 13:46:20","TRT01SDTM":"2020-10-24 19:46:20","TRT01EDTM":"2022-10-25 07:46:20","TRT02SDTM":"2022-10-25 07:46:20","TRT02EDTM":"2023-10-25 13:46:20","AP01SDTM":"2020-10-24 19:46:20","AP01EDTM":"2022-10-25 07:46:20","AP02SDTM":"2022-10-25 07:46:20","AP02EDTM":"2023-10-25 13:46:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-25","EOSDY":1096,"LSTALVDT":"2023-11-14","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7006,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.18497,"AVALU":"mg/L","BASE2":7.89705,"BASE":8.26519,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.28791,"PCHG2":28.97176,"CHG":1.91978,"PCHG":23.22729,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-06-26 19:46:20","ADY":245,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-13-id-80","SUBJID":"id-80","SITEID":"GBR-13","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-13","INVNAM":"Dr. GBR-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":7.74987,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 19:46:20","TRTEDTM":"2023-10-25 13:46:20","TRT01SDTM":"2020-10-24 19:46:20","TRT01EDTM":"2022-10-25 07:46:20","TRT02SDTM":"2022-10-25 07:46:20","TRT02EDTM":"2023-10-25 13:46:20","AP01SDTM":"2020-10-24 19:46:20","AP01EDTM":"2022-10-25 07:46:20","AP02SDTM":"2022-10-25 07:46:20","AP02EDTM":"2023-10-25 13:46:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-25","EOSDY":1096,"LSTALVDT":"2023-11-14","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4420,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.32803,"AVALU":"mg/L","BASE2":7.89705,"BASE":8.26519,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.43098,"PCHG2":18.12039,"CHG":1.06284,"PCHG":12.85926,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-27 19:46:20","ADY":611,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-13-id-80","SUBJID":"id-80","SITEID":"GBR-13","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-13","INVNAM":"Dr. GBR-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":7.74987,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 19:46:20","TRTEDTM":"2023-10-25 13:46:20","TRT01SDTM":"2020-10-24 19:46:20","TRT01EDTM":"2022-10-25 07:46:20","TRT02SDTM":"2022-10-25 07:46:20","TRT02EDTM":"2023-10-25 13:46:20","AP01SDTM":"2020-10-24 19:46:20","AP01EDTM":"2022-10-25 07:46:20","AP02SDTM":"2022-10-25 07:46:20","AP02EDTM":"2023-10-25 13:46:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-25","EOSDY":1096,"LSTALVDT":"2023-11-14","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6642,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.28712,"AVALU":"mg/L","BASE2":7.89705,"BASE":8.26519,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.39007,"PCHG2":4.93941,"CHG":0.02193,"PCHG":0.26536,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-28 19:46:20","ADY":916,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-13-id-80","SUBJID":"id-80","SITEID":"GBR-13","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-13","INVNAM":"Dr. GBR-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":7.74987,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 19:46:20","TRTEDTM":"2023-10-25 13:46:20","TRT01SDTM":"2020-10-24 19:46:20","TRT01EDTM":"2022-10-25 07:46:20","TRT02SDTM":"2022-10-25 07:46:20","TRT02EDTM":"2023-10-25 13:46:20","AP01SDTM":"2020-10-24 19:46:20","AP01EDTM":"2022-10-25 07:46:20","AP02SDTM":"2022-10-25 07:46:20","AP02EDTM":"2023-10-25 13:46:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-25","EOSDY":1096,"LSTALVDT":"2023-11-14","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6175,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.51919,"AVALU":"mg/L","BASE2":7.89705,"BASE":8.26519,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.62213,"PCHG2":33.20397,"CHG":2.254,"PCHG":27.271,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2023-08-09 19:46:20","ADY":1019,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-13-id-80","SUBJID":"id-80","SITEID":"GBR-13","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-13","INVNAM":"Dr. GBR-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":7.74987,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 19:46:20","TRTEDTM":"2023-10-25 13:46:20","TRT01SDTM":"2020-10-24 19:46:20","TRT01EDTM":"2022-10-25 07:46:20","TRT02SDTM":"2022-10-25 07:46:20","TRT02EDTM":"2023-10-25 13:46:20","AP01SDTM":"2020-10-24 19:46:20","AP01EDTM":"2022-10-25 07:46:20","AP02SDTM":"2022-10-25 07:46:20","AP02EDTM":"2023-10-25 13:46:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-25","EOSDY":1096,"LSTALVDT":"2023-11-14","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7148,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.17485,"AVALU":"mg/L","BASE2":7.89705,"BASE":8.26519,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.2778,"PCHG2":3.51771,"CHG":-0.09034,"PCHG":-1.09302,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-30 19:46:20","ADY":1040,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-13-id-80","SUBJID":"id-80","SITEID":"GBR-13","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-13","INVNAM":"Dr. GBR-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":7.74987,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 19:46:20","TRTEDTM":"2023-10-25 13:46:20","TRT01SDTM":"2020-10-24 19:46:20","TRT01EDTM":"2022-10-25 07:46:20","TRT02SDTM":"2022-10-25 07:46:20","TRT02EDTM":"2023-10-25 13:46:20","AP01SDTM":"2020-10-24 19:46:20","AP01EDTM":"2022-10-25 07:46:20","AP02SDTM":"2022-10-25 07:46:20","AP02EDTM":"2023-10-25 13:46:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-25","EOSDY":1096,"LSTALVDT":"2023-11-14","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6677,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.848,"AVALU":"g/L","BASE2":2.848,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-30 19:46:20","ADY":37,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-13-id-80","SUBJID":"id-80","SITEID":"GBR-13","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-13","INVNAM":"Dr. GBR-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":7.74987,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 19:46:20","TRTEDTM":"2023-10-25 13:46:20","TRT01SDTM":"2020-10-24 19:46:20","TRT01EDTM":"2022-10-25 07:46:20","TRT02SDTM":"2022-10-25 07:46:20","TRT02EDTM":"2023-10-25 13:46:20","AP01SDTM":"2020-10-24 19:46:20","AP01EDTM":"2022-10-25 07:46:20","AP02SDTM":"2022-10-25 07:46:20","AP02EDTM":"2023-10-25 13:46:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-25","EOSDY":1096,"LSTALVDT":"2023-11-14","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6154,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81987,"AVALU":"g/L","BASE2":2.848,"BASE":2.81987,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.02813,"PCHG2":-0.98756,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-31 19:46:20","ADY":68,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-13-id-80","SUBJID":"id-80","SITEID":"GBR-13","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-13","INVNAM":"Dr. GBR-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":7.74987,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 19:46:20","TRTEDTM":"2023-10-25 13:46:20","TRT01SDTM":"2020-10-24 19:46:20","TRT01EDTM":"2022-10-25 07:46:20","TRT02SDTM":"2022-10-25 07:46:20","TRT02EDTM":"2023-10-25 13:46:20","AP01SDTM":"2020-10-24 19:46:20","AP01EDTM":"2022-10-25 07:46:20","AP02SDTM":"2022-10-25 07:46:20","AP02EDTM":"2023-10-25 13:46:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-25","EOSDY":1096,"LSTALVDT":"2023-11-14","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3290,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97941,"AVALU":"g/L","BASE2":2.848,"BASE":2.81987,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13141,"PCHG2":4.61424,"CHG":0.15954,"PCHG":5.65767,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-26 19:46:20","ADY":245,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-13-id-80","SUBJID":"id-80","SITEID":"GBR-13","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-13","INVNAM":"Dr. GBR-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":7.74987,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 19:46:20","TRTEDTM":"2023-10-25 13:46:20","TRT01SDTM":"2020-10-24 19:46:20","TRT01EDTM":"2022-10-25 07:46:20","TRT02SDTM":"2022-10-25 07:46:20","TRT02EDTM":"2023-10-25 13:46:20","AP01SDTM":"2020-10-24 19:46:20","AP01EDTM":"2022-10-25 07:46:20","AP02SDTM":"2022-10-25 07:46:20","AP02EDTM":"2023-10-25 13:46:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-25","EOSDY":1096,"LSTALVDT":"2023-11-14","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5982,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86148,"AVALU":"g/L","BASE2":2.848,"BASE":2.81987,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01348,"PCHG2":0.47347,"CHG":0.04161,"PCHG":1.4756,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-27 19:46:20","ADY":611,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-13-id-80","SUBJID":"id-80","SITEID":"GBR-13","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-13","INVNAM":"Dr. GBR-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":7.74987,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 19:46:20","TRTEDTM":"2023-10-25 13:46:20","TRT01SDTM":"2020-10-24 19:46:20","TRT01EDTM":"2022-10-25 07:46:20","TRT02SDTM":"2022-10-25 07:46:20","TRT02EDTM":"2023-10-25 13:46:20","AP01SDTM":"2020-10-24 19:46:20","AP01EDTM":"2022-10-25 07:46:20","AP02SDTM":"2022-10-25 07:46:20","AP02EDTM":"2023-10-25 13:46:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-25","EOSDY":1096,"LSTALVDT":"2023-11-14","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7658,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89238,"AVALU":"g/L","BASE2":2.848,"BASE":2.81987,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04439,"PCHG2":1.55849,"CHG":0.07251,"PCHG":2.57144,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-28 19:46:20","ADY":916,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-13-id-80","SUBJID":"id-80","SITEID":"GBR-13","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-13","INVNAM":"Dr. GBR-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":7.74987,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 19:46:20","TRTEDTM":"2023-10-25 13:46:20","TRT01SDTM":"2020-10-24 19:46:20","TRT01EDTM":"2022-10-25 07:46:20","TRT02SDTM":"2022-10-25 07:46:20","TRT02EDTM":"2023-10-25 13:46:20","AP01SDTM":"2020-10-24 19:46:20","AP01EDTM":"2022-10-25 07:46:20","AP02SDTM":"2022-10-25 07:46:20","AP02EDTM":"2023-10-25 13:46:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-25","EOSDY":1096,"LSTALVDT":"2023-11-14","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4879,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00089,"AVALU":"g/L","BASE2":2.848,"BASE":2.81987,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15289,"PCHG2":5.36837,"CHG":0.18102,"PCHG":6.41932,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2023-08-09 19:46:20","ADY":1019,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-13-id-80","SUBJID":"id-80","SITEID":"GBR-13","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-13","INVNAM":"Dr. GBR-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Europe","STRATA1":"C","STRATA2":"S1","BMRKR1":7.74987,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-21","TRTSDTM":"2020-10-24 19:46:20","TRTEDTM":"2023-10-25 13:46:20","TRT01SDTM":"2020-10-24 19:46:20","TRT01EDTM":"2022-10-25 07:46:20","TRT02SDTM":"2022-10-25 07:46:20","TRT02EDTM":"2023-10-25 13:46:20","AP01SDTM":"2020-10-24 19:46:20","AP01EDTM":"2022-10-25 07:46:20","AP02SDTM":"2022-10-25 07:46:20","AP02EDTM":"2023-10-25 13:46:20","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-25","EOSDY":1096,"LSTALVDT":"2023-11-14","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5031,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84196,"AVALU":"g/L","BASE2":2.848,"BASE":2.81987,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00604,"PCHG2":-0.21203,"CHG":0.02209,"PCHG":0.78326,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-30 19:46:20","ADY":1040,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-15-id-293","SUBJID":"id-293","SITEID":"GBR-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-15","INVNAM":"Dr. GBR-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S1","BMRKR1":1.56299,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-18","TRTSDTM":"2020-05-21 08:57:46","TRTEDTM":"2023-05-22 02:57:46","TRT01SDTM":"2020-05-21 08:57:46","TRT01EDTM":"2022-05-21 20:57:46","TRT02SDTM":"2022-05-21 20:57:46","TRT02EDTM":"2023-05-22 02:57:46","AP01SDTM":"2020-05-21 08:57:46","AP01EDTM":"2022-05-21 20:57:46","AP02SDTM":"2022-05-21 20:57:46","AP02EDTM":"2023-05-22 02:57:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-22","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7504,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.74732,"AVALU":"U/L","BASE2":13.74732,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-27 08:57:46","ADY":282,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-15-id-293","SUBJID":"id-293","SITEID":"GBR-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-15","INVNAM":"Dr. GBR-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S1","BMRKR1":1.56299,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-18","TRTSDTM":"2020-05-21 08:57:46","TRTEDTM":"2023-05-22 02:57:46","TRT01SDTM":"2020-05-21 08:57:46","TRT01EDTM":"2022-05-21 20:57:46","TRT02SDTM":"2022-05-21 20:57:46","TRT02EDTM":"2023-05-22 02:57:46","AP01SDTM":"2020-05-21 08:57:46","AP01EDTM":"2022-05-21 20:57:46","AP02SDTM":"2022-05-21 20:57:46","AP02EDTM":"2023-05-22 02:57:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-22","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7885,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.97049,"AVALU":"U/L","BASE2":13.74732,"BASE":32.97049,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":19.22317,"PCHG2":139.83211,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-30 08:57:46","ADY":435,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-15-id-293","SUBJID":"id-293","SITEID":"GBR-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-15","INVNAM":"Dr. GBR-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S1","BMRKR1":1.56299,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-18","TRTSDTM":"2020-05-21 08:57:46","TRTEDTM":"2023-05-22 02:57:46","TRT01SDTM":"2020-05-21 08:57:46","TRT01EDTM":"2022-05-21 20:57:46","TRT02SDTM":"2022-05-21 20:57:46","TRT02EDTM":"2023-05-22 02:57:46","AP01SDTM":"2020-05-21 08:57:46","AP01EDTM":"2022-05-21 20:57:46","AP02SDTM":"2022-05-21 20:57:46","AP02EDTM":"2023-05-22 02:57:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-22","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6490,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.66141,"AVALU":"U/L","BASE2":13.74732,"BASE":32.97049,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.08592,"PCHG2":-87.91468,"CHG":-31.30909,"PCHG":-94.96093,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-12-02 08:57:46","ADY":560,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-15-id-293","SUBJID":"id-293","SITEID":"GBR-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-15","INVNAM":"Dr. GBR-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S1","BMRKR1":1.56299,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-18","TRTSDTM":"2020-05-21 08:57:46","TRTEDTM":"2023-05-22 02:57:46","TRT01SDTM":"2020-05-21 08:57:46","TRT01EDTM":"2022-05-21 20:57:46","TRT02SDTM":"2022-05-21 20:57:46","TRT02EDTM":"2023-05-22 02:57:46","AP01SDTM":"2020-05-21 08:57:46","AP01EDTM":"2022-05-21 20:57:46","AP02SDTM":"2022-05-21 20:57:46","AP02EDTM":"2023-05-22 02:57:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-22","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6403,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.24793,"AVALU":"U/L","BASE2":13.74732,"BASE":32.97049,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.50061,"PCHG2":134.5761,"CHG":-0.72256,"PCHG":-2.19154,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-07 08:57:46","ADY":565,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-15-id-293","SUBJID":"id-293","SITEID":"GBR-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-15","INVNAM":"Dr. GBR-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S1","BMRKR1":1.56299,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-18","TRTSDTM":"2020-05-21 08:57:46","TRTEDTM":"2023-05-22 02:57:46","TRT01SDTM":"2020-05-21 08:57:46","TRT01EDTM":"2022-05-21 20:57:46","TRT02SDTM":"2022-05-21 20:57:46","TRT02EDTM":"2023-05-22 02:57:46","AP01SDTM":"2020-05-21 08:57:46","AP01EDTM":"2022-05-21 20:57:46","AP02SDTM":"2022-05-21 20:57:46","AP02EDTM":"2023-05-22 02:57:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-22","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4490,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.75285,"AVALU":"U/L","BASE2":13.74732,"BASE":32.97049,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.99447,"PCHG2":-87.24953,"CHG":-31.21765,"PCHG":-94.68358,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-01-21 08:57:46","ADY":610,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-15-id-293","SUBJID":"id-293","SITEID":"GBR-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-15","INVNAM":"Dr. GBR-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S1","BMRKR1":1.56299,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-18","TRTSDTM":"2020-05-21 08:57:46","TRTEDTM":"2023-05-22 02:57:46","TRT01SDTM":"2020-05-21 08:57:46","TRT01EDTM":"2022-05-21 20:57:46","TRT02SDTM":"2022-05-21 20:57:46","TRT02EDTM":"2023-05-22 02:57:46","AP01SDTM":"2020-05-21 08:57:46","AP01EDTM":"2022-05-21 20:57:46","AP02SDTM":"2022-05-21 20:57:46","AP02EDTM":"2023-05-22 02:57:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-22","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":159,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.47232,"AVALU":"U/L","BASE2":13.74732,"BASE":32.97049,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.27501,"PCHG2":-31.097,"CHG":-23.49818,"PCHG":-71.27032,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-11 08:57:46","ADY":659,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-15-id-293","SUBJID":"id-293","SITEID":"GBR-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-15","INVNAM":"Dr. GBR-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S1","BMRKR1":1.56299,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-18","TRTSDTM":"2020-05-21 08:57:46","TRTEDTM":"2023-05-22 02:57:46","TRT01SDTM":"2020-05-21 08:57:46","TRT01EDTM":"2022-05-21 20:57:46","TRT02SDTM":"2022-05-21 20:57:46","TRT02EDTM":"2023-05-22 02:57:46","AP01SDTM":"2020-05-21 08:57:46","AP01EDTM":"2022-05-21 20:57:46","AP02SDTM":"2022-05-21 20:57:46","AP02EDTM":"2023-05-22 02:57:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-22","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6580,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.61952,"AVALU":"U/L","BASE2":13.74732,"BASE":32.97049,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.8722,"PCHG2":20.89281,"CHG":-16.35097,"PCHG":-49.59273,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-24 08:57:46","ADY":794,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-15-id-293","SUBJID":"id-293","SITEID":"GBR-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-15","INVNAM":"Dr. GBR-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S1","BMRKR1":1.56299,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-18","TRTSDTM":"2020-05-21 08:57:46","TRTEDTM":"2023-05-22 02:57:46","TRT01SDTM":"2020-05-21 08:57:46","TRT01EDTM":"2022-05-21 20:57:46","TRT02SDTM":"2022-05-21 20:57:46","TRT02EDTM":"2023-05-22 02:57:46","AP01SDTM":"2020-05-21 08:57:46","AP01EDTM":"2022-05-21 20:57:46","AP02SDTM":"2022-05-21 20:57:46","AP02EDTM":"2023-05-22 02:57:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-22","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8142,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.51979,"AVALU":"mg/L","BASE2":7.51979,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-02-27 08:57:46","ADY":282,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-15-id-293","SUBJID":"id-293","SITEID":"GBR-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-15","INVNAM":"Dr. GBR-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S1","BMRKR1":1.56299,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-18","TRTSDTM":"2020-05-21 08:57:46","TRTEDTM":"2023-05-22 02:57:46","TRT01SDTM":"2020-05-21 08:57:46","TRT01EDTM":"2022-05-21 20:57:46","TRT02SDTM":"2022-05-21 20:57:46","TRT02EDTM":"2023-05-22 02:57:46","AP01SDTM":"2020-05-21 08:57:46","AP01EDTM":"2022-05-21 20:57:46","AP02SDTM":"2022-05-21 20:57:46","AP02EDTM":"2023-05-22 02:57:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-22","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6472,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.74433,"AVALU":"mg/L","BASE2":7.51979,"BASE":8.74433,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.22454,"PCHG2":16.28427,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-30 08:57:46","ADY":435,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-15-id-293","SUBJID":"id-293","SITEID":"GBR-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-15","INVNAM":"Dr. GBR-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S1","BMRKR1":1.56299,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-18","TRTSDTM":"2020-05-21 08:57:46","TRTEDTM":"2023-05-22 02:57:46","TRT01SDTM":"2020-05-21 08:57:46","TRT01EDTM":"2022-05-21 20:57:46","TRT02SDTM":"2022-05-21 20:57:46","TRT02EDTM":"2023-05-22 02:57:46","AP01SDTM":"2020-05-21 08:57:46","AP01EDTM":"2022-05-21 20:57:46","AP02SDTM":"2022-05-21 20:57:46","AP02EDTM":"2023-05-22 02:57:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-22","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2375,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.9844,"AVALU":"mg/L","BASE2":7.51979,"BASE":8.74433,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.46461,"PCHG2":32.77504,"CHG":1.24007,"PCHG":14.18143,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-02 08:57:46","ADY":560,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-15-id-293","SUBJID":"id-293","SITEID":"GBR-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-15","INVNAM":"Dr. GBR-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S1","BMRKR1":1.56299,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-18","TRTSDTM":"2020-05-21 08:57:46","TRTEDTM":"2023-05-22 02:57:46","TRT01SDTM":"2020-05-21 08:57:46","TRT01EDTM":"2022-05-21 20:57:46","TRT02SDTM":"2022-05-21 20:57:46","TRT02EDTM":"2023-05-22 02:57:46","AP01SDTM":"2020-05-21 08:57:46","AP01EDTM":"2022-05-21 20:57:46","AP02SDTM":"2022-05-21 20:57:46","AP02EDTM":"2023-05-22 02:57:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-22","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6967,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.13594,"AVALU":"mg/L","BASE2":7.51979,"BASE":8.74433,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.61615,"PCHG2":34.79023,"CHG":1.39161,"PCHG":15.91442,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-12-07 08:57:46","ADY":565,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-15-id-293","SUBJID":"id-293","SITEID":"GBR-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-15","INVNAM":"Dr. GBR-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S1","BMRKR1":1.56299,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-18","TRTSDTM":"2020-05-21 08:57:46","TRTEDTM":"2023-05-22 02:57:46","TRT01SDTM":"2020-05-21 08:57:46","TRT01EDTM":"2022-05-21 20:57:46","TRT02SDTM":"2022-05-21 20:57:46","TRT02EDTM":"2023-05-22 02:57:46","AP01SDTM":"2020-05-21 08:57:46","AP01EDTM":"2022-05-21 20:57:46","AP02SDTM":"2022-05-21 20:57:46","AP02EDTM":"2023-05-22 02:57:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-22","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4214,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.2845,"AVALU":"mg/L","BASE2":7.51979,"BASE":8.74433,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.76472,"PCHG2":23.46767,"CHG":0.54018,"PCHG":6.17745,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-21 08:57:46","ADY":610,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-15-id-293","SUBJID":"id-293","SITEID":"GBR-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-15","INVNAM":"Dr. GBR-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S1","BMRKR1":1.56299,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-18","TRTSDTM":"2020-05-21 08:57:46","TRTEDTM":"2023-05-22 02:57:46","TRT01SDTM":"2020-05-21 08:57:46","TRT01EDTM":"2022-05-21 20:57:46","TRT02SDTM":"2022-05-21 20:57:46","TRT02EDTM":"2023-05-22 02:57:46","AP01SDTM":"2020-05-21 08:57:46","AP01EDTM":"2022-05-21 20:57:46","AP02SDTM":"2022-05-21 20:57:46","AP02EDTM":"2023-05-22 02:57:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-22","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4180,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.00132,"AVALU":"mg/L","BASE2":7.51979,"BASE":8.74433,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.48153,"PCHG2":33.00001,"CHG":1.25699,"PCHG":14.37489,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-03-11 08:57:46","ADY":659,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-15-id-293","SUBJID":"id-293","SITEID":"GBR-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-15","INVNAM":"Dr. GBR-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S1","BMRKR1":1.56299,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-18","TRTSDTM":"2020-05-21 08:57:46","TRTEDTM":"2023-05-22 02:57:46","TRT01SDTM":"2020-05-21 08:57:46","TRT01EDTM":"2022-05-21 20:57:46","TRT02SDTM":"2022-05-21 20:57:46","TRT02EDTM":"2023-05-22 02:57:46","AP01SDTM":"2020-05-21 08:57:46","AP01EDTM":"2022-05-21 20:57:46","AP02SDTM":"2022-05-21 20:57:46","AP02EDTM":"2023-05-22 02:57:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-22","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":678,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.69451,"AVALU":"mg/L","BASE2":7.51979,"BASE":8.74433,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.17472,"PCHG2":15.62177,"CHG":-0.04982,"PCHG":-0.56972,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-24 08:57:46","ADY":794,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-15-id-293","SUBJID":"id-293","SITEID":"GBR-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-15","INVNAM":"Dr. GBR-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S1","BMRKR1":1.56299,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-18","TRTSDTM":"2020-05-21 08:57:46","TRTEDTM":"2023-05-22 02:57:46","TRT01SDTM":"2020-05-21 08:57:46","TRT01EDTM":"2022-05-21 20:57:46","TRT02SDTM":"2022-05-21 20:57:46","TRT02EDTM":"2023-05-22 02:57:46","AP01SDTM":"2020-05-21 08:57:46","AP01EDTM":"2022-05-21 20:57:46","AP02SDTM":"2022-05-21 20:57:46","AP02EDTM":"2023-05-22 02:57:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-22","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4358,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95343,"AVALU":"g/L","BASE2":2.95343,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-27 08:57:46","ADY":282,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-15-id-293","SUBJID":"id-293","SITEID":"GBR-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-15","INVNAM":"Dr. GBR-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S1","BMRKR1":1.56299,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-18","TRTSDTM":"2020-05-21 08:57:46","TRTEDTM":"2023-05-22 02:57:46","TRT01SDTM":"2020-05-21 08:57:46","TRT01EDTM":"2022-05-21 20:57:46","TRT02SDTM":"2022-05-21 20:57:46","TRT02EDTM":"2023-05-22 02:57:46","AP01SDTM":"2020-05-21 08:57:46","AP01EDTM":"2022-05-21 20:57:46","AP02SDTM":"2022-05-21 20:57:46","AP02EDTM":"2023-05-22 02:57:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-22","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2411,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79302,"AVALU":"g/L","BASE2":2.95343,"BASE":2.79302,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.16041,"PCHG2":-5.43134,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-30 08:57:46","ADY":435,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-15-id-293","SUBJID":"id-293","SITEID":"GBR-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-15","INVNAM":"Dr. GBR-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S1","BMRKR1":1.56299,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-18","TRTSDTM":"2020-05-21 08:57:46","TRTEDTM":"2023-05-22 02:57:46","TRT01SDTM":"2020-05-21 08:57:46","TRT01EDTM":"2022-05-21 20:57:46","TRT02SDTM":"2022-05-21 20:57:46","TRT02EDTM":"2023-05-22 02:57:46","AP01SDTM":"2020-05-21 08:57:46","AP01EDTM":"2022-05-21 20:57:46","AP02SDTM":"2022-05-21 20:57:46","AP02EDTM":"2023-05-22 02:57:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-22","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3146,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03904,"AVALU":"g/L","BASE2":2.95343,"BASE":2.79302,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08561,"PCHG2":2.89859,"CHG":0.24602,"PCHG":8.80834,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-12-02 08:57:46","ADY":560,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-15-id-293","SUBJID":"id-293","SITEID":"GBR-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-15","INVNAM":"Dr. GBR-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S1","BMRKR1":1.56299,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-18","TRTSDTM":"2020-05-21 08:57:46","TRTEDTM":"2023-05-22 02:57:46","TRT01SDTM":"2020-05-21 08:57:46","TRT01EDTM":"2022-05-21 20:57:46","TRT02SDTM":"2022-05-21 20:57:46","TRT02EDTM":"2023-05-22 02:57:46","AP01SDTM":"2020-05-21 08:57:46","AP01EDTM":"2022-05-21 20:57:46","AP02SDTM":"2022-05-21 20:57:46","AP02EDTM":"2023-05-22 02:57:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-22","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1660,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90247,"AVALU":"g/L","BASE2":2.95343,"BASE":2.79302,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05096,"PCHG2":-1.72562,"CHG":0.10945,"PCHG":3.91855,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-07 08:57:46","ADY":565,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-15-id-293","SUBJID":"id-293","SITEID":"GBR-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-15","INVNAM":"Dr. GBR-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S1","BMRKR1":1.56299,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-18","TRTSDTM":"2020-05-21 08:57:46","TRTEDTM":"2023-05-22 02:57:46","TRT01SDTM":"2020-05-21 08:57:46","TRT01EDTM":"2022-05-21 20:57:46","TRT02SDTM":"2022-05-21 20:57:46","TRT02EDTM":"2023-05-22 02:57:46","AP01SDTM":"2020-05-21 08:57:46","AP01EDTM":"2022-05-21 20:57:46","AP02SDTM":"2022-05-21 20:57:46","AP02EDTM":"2023-05-22 02:57:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-22","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3021,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.66991,"AVALU":"g/L","BASE2":2.95343,"BASE":2.79302,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.28352,"PCHG2":-9.5997,"CHG":-0.12311,"PCHG":-4.40776,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-21 08:57:46","ADY":610,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-15-id-293","SUBJID":"id-293","SITEID":"GBR-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-15","INVNAM":"Dr. GBR-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S1","BMRKR1":1.56299,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-18","TRTSDTM":"2020-05-21 08:57:46","TRTEDTM":"2023-05-22 02:57:46","TRT01SDTM":"2020-05-21 08:57:46","TRT01EDTM":"2022-05-21 20:57:46","TRT02SDTM":"2022-05-21 20:57:46","TRT02EDTM":"2023-05-22 02:57:46","AP01SDTM":"2020-05-21 08:57:46","AP01EDTM":"2022-05-21 20:57:46","AP02SDTM":"2022-05-21 20:57:46","AP02EDTM":"2023-05-22 02:57:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-22","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8065,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05154,"AVALU":"g/L","BASE2":2.95343,"BASE":2.79302,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09811,"PCHG2":3.32192,"CHG":0.25852,"PCHG":9.25598,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-03-11 08:57:46","ADY":659,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-15-id-293","SUBJID":"id-293","SITEID":"GBR-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-15","INVNAM":"Dr. GBR-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S1","BMRKR1":1.56299,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-18","TRTSDTM":"2020-05-21 08:57:46","TRTEDTM":"2023-05-22 02:57:46","TRT01SDTM":"2020-05-21 08:57:46","TRT01EDTM":"2022-05-21 20:57:46","TRT02SDTM":"2022-05-21 20:57:46","TRT02EDTM":"2023-05-22 02:57:46","AP01SDTM":"2020-05-21 08:57:46","AP01EDTM":"2022-05-21 20:57:46","AP02SDTM":"2022-05-21 20:57:46","AP02EDTM":"2023-05-22 02:57:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-22","EOSDY":1096,"LSTALVDT":"2023-06-02","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7101,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04747,"AVALU":"g/L","BASE2":2.95343,"BASE":2.79302,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09404,"PCHG2":3.1841,"CHG":0.25445,"PCHG":9.11025,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-07-24 08:57:46","ADY":794,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-17-id-211","SUBJID":"id-211","SITEID":"GBR-17","AGE":62,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-17","INVNAM":"Dr. GBR-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":3.72545,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-23 03:12:22","TRTEDTM":"2022-02-19 04:06:37","TRT01SDTM":"2020-12-23 03:12:22","TRT01EDTM":"2021-02-18 22:06:37","TRT02SDTM":"2021-02-18 22:06:37","TRT02EDTM":"2022-02-19 04:06:37","AP01SDTM":"2020-12-23 03:12:22","AP01EDTM":"2021-02-18 22:06:37","AP02SDTM":"2021-02-18 22:06:37","AP02EDTM":"2022-02-19 04:06:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":424,"DCSREAS":"DEATH","DTHDT":"2022-03-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":33,"LDDTHGR1":">30","LSTALVDT":"2022-03-24","DTHADY":455,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7602,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.76919,"AVALU":"U/L","BASE2":9.76919,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-25 03:12:22","ADY":2,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-17-id-211","SUBJID":"id-211","SITEID":"GBR-17","AGE":62,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-17","INVNAM":"Dr. GBR-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":3.72545,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-23 03:12:22","TRTEDTM":"2022-02-19 04:06:37","TRT01SDTM":"2020-12-23 03:12:22","TRT01EDTM":"2021-02-18 22:06:37","TRT02SDTM":"2021-02-18 22:06:37","TRT02EDTM":"2022-02-19 04:06:37","AP01SDTM":"2020-12-23 03:12:22","AP01EDTM":"2021-02-18 22:06:37","AP02SDTM":"2021-02-18 22:06:37","AP02EDTM":"2022-02-19 04:06:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":424,"DCSREAS":"DEATH","DTHDT":"2022-03-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":33,"LDDTHGR1":">30","LSTALVDT":"2022-03-24","DTHADY":455,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8124,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.57993,"AVALU":"U/L","BASE2":9.76919,"BASE":21.57993,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":11.81074,"PCHG2":120.89788,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-06 03:12:22","ADY":73,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-17-id-211","SUBJID":"id-211","SITEID":"GBR-17","AGE":62,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-17","INVNAM":"Dr. GBR-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":3.72545,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-23 03:12:22","TRTEDTM":"2022-02-19 04:06:37","TRT01SDTM":"2020-12-23 03:12:22","TRT01EDTM":"2021-02-18 22:06:37","TRT02SDTM":"2021-02-18 22:06:37","TRT02EDTM":"2022-02-19 04:06:37","AP01SDTM":"2020-12-23 03:12:22","AP01EDTM":"2021-02-18 22:06:37","AP02SDTM":"2021-02-18 22:06:37","AP02EDTM":"2022-02-19 04:06:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":424,"DCSREAS":"DEATH","DTHDT":"2022-03-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":33,"LDDTHGR1":">30","LSTALVDT":"2022-03-24","DTHADY":455,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":323,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.54411,"AVALU":"U/L","BASE2":9.76919,"BASE":21.57993,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.77492,"PCHG2":120.53123,"CHG":-0.03582,"PCHG":-0.16598,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-29 03:12:22","ADY":96,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-17-id-211","SUBJID":"id-211","SITEID":"GBR-17","AGE":62,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-17","INVNAM":"Dr. GBR-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":3.72545,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-23 03:12:22","TRTEDTM":"2022-02-19 04:06:37","TRT01SDTM":"2020-12-23 03:12:22","TRT01EDTM":"2021-02-18 22:06:37","TRT02SDTM":"2021-02-18 22:06:37","TRT02EDTM":"2022-02-19 04:06:37","AP01SDTM":"2020-12-23 03:12:22","AP01EDTM":"2021-02-18 22:06:37","AP02SDTM":"2021-02-18 22:06:37","AP02EDTM":"2022-02-19 04:06:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":424,"DCSREAS":"DEATH","DTHDT":"2022-03-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":33,"LDDTHGR1":">30","LSTALVDT":"2022-03-24","DTHADY":455,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3774,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.5302,"AVALU":"U/L","BASE2":9.76919,"BASE":21.57993,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.76101,"PCHG2":130.62511,"CHG":0.95027,"PCHG":4.4035,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-02 03:12:22","ADY":161,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-17-id-211","SUBJID":"id-211","SITEID":"GBR-17","AGE":62,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-17","INVNAM":"Dr. GBR-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":3.72545,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-23 03:12:22","TRTEDTM":"2022-02-19 04:06:37","TRT01SDTM":"2020-12-23 03:12:22","TRT01EDTM":"2021-02-18 22:06:37","TRT02SDTM":"2021-02-18 22:06:37","TRT02EDTM":"2022-02-19 04:06:37","AP01SDTM":"2020-12-23 03:12:22","AP01EDTM":"2021-02-18 22:06:37","AP02SDTM":"2021-02-18 22:06:37","AP02EDTM":"2022-02-19 04:06:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":424,"DCSREAS":"DEATH","DTHDT":"2022-03-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":33,"LDDTHGR1":">30","LSTALVDT":"2022-03-24","DTHADY":455,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5573,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.40246,"AVALU":"U/L","BASE2":9.76919,"BASE":21.57993,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.63327,"PCHG2":139.55381,"CHG":1.82253,"PCHG":8.4455,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-09 03:12:22","ADY":168,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-17-id-211","SUBJID":"id-211","SITEID":"GBR-17","AGE":62,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-17","INVNAM":"Dr. GBR-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":3.72545,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-23 03:12:22","TRTEDTM":"2022-02-19 04:06:37","TRT01SDTM":"2020-12-23 03:12:22","TRT01EDTM":"2021-02-18 22:06:37","TRT02SDTM":"2021-02-18 22:06:37","TRT02EDTM":"2022-02-19 04:06:37","AP01SDTM":"2020-12-23 03:12:22","AP01EDTM":"2021-02-18 22:06:37","AP02SDTM":"2021-02-18 22:06:37","AP02EDTM":"2022-02-19 04:06:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":424,"DCSREAS":"DEATH","DTHDT":"2022-03-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":33,"LDDTHGR1":">30","LSTALVDT":"2022-03-24","DTHADY":455,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1143,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.51023,"AVALU":"U/L","BASE2":9.76919,"BASE":21.57993,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.74105,"PCHG2":202.07456,"CHG":7.9303,"PCHG":36.74851,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-17 03:12:22","ADY":390,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-17-id-211","SUBJID":"id-211","SITEID":"GBR-17","AGE":62,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-17","INVNAM":"Dr. GBR-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":3.72545,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-23 03:12:22","TRTEDTM":"2022-02-19 04:06:37","TRT01SDTM":"2020-12-23 03:12:22","TRT01EDTM":"2021-02-18 22:06:37","TRT02SDTM":"2021-02-18 22:06:37","TRT02EDTM":"2022-02-19 04:06:37","AP01SDTM":"2020-12-23 03:12:22","AP01EDTM":"2021-02-18 22:06:37","AP02SDTM":"2021-02-18 22:06:37","AP02EDTM":"2022-02-19 04:06:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":424,"DCSREAS":"DEATH","DTHDT":"2022-03-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":33,"LDDTHGR1":">30","LSTALVDT":"2022-03-24","DTHADY":455,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":256,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":37.69631,"AVALU":"U/L","BASE2":9.76919,"BASE":21.57993,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":27.92712,"PCHG2":285.86943,"CHG":16.11638,"PCHG":74.68227,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-02 03:12:22","ADY":406,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-17-id-211","SUBJID":"id-211","SITEID":"GBR-17","AGE":62,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-17","INVNAM":"Dr. GBR-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":3.72545,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-23 03:12:22","TRTEDTM":"2022-02-19 04:06:37","TRT01SDTM":"2020-12-23 03:12:22","TRT01EDTM":"2021-02-18 22:06:37","TRT02SDTM":"2021-02-18 22:06:37","TRT02EDTM":"2022-02-19 04:06:37","AP01SDTM":"2020-12-23 03:12:22","AP01EDTM":"2021-02-18 22:06:37","AP02SDTM":"2021-02-18 22:06:37","AP02EDTM":"2022-02-19 04:06:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":424,"DCSREAS":"DEATH","DTHDT":"2022-03-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":33,"LDDTHGR1":">30","LSTALVDT":"2022-03-24","DTHADY":455,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6192,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.80031,"AVALU":"mg/L","BASE2":8.80031,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-25 03:12:22","ADY":2,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-17-id-211","SUBJID":"id-211","SITEID":"GBR-17","AGE":62,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-17","INVNAM":"Dr. GBR-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":3.72545,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-23 03:12:22","TRTEDTM":"2022-02-19 04:06:37","TRT01SDTM":"2020-12-23 03:12:22","TRT01EDTM":"2021-02-18 22:06:37","TRT02SDTM":"2021-02-18 22:06:37","TRT02EDTM":"2022-02-19 04:06:37","AP01SDTM":"2020-12-23 03:12:22","AP01EDTM":"2021-02-18 22:06:37","AP02SDTM":"2021-02-18 22:06:37","AP02EDTM":"2022-02-19 04:06:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":424,"DCSREAS":"DEATH","DTHDT":"2022-03-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":33,"LDDTHGR1":">30","LSTALVDT":"2022-03-24","DTHADY":455,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5436,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.9414,"AVALU":"mg/L","BASE2":8.80031,"BASE":9.9414,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.14109,"PCHG2":12.96644,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-06 03:12:22","ADY":73,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-17-id-211","SUBJID":"id-211","SITEID":"GBR-17","AGE":62,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-17","INVNAM":"Dr. GBR-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":3.72545,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-23 03:12:22","TRTEDTM":"2022-02-19 04:06:37","TRT01SDTM":"2020-12-23 03:12:22","TRT01EDTM":"2021-02-18 22:06:37","TRT02SDTM":"2021-02-18 22:06:37","TRT02EDTM":"2022-02-19 04:06:37","AP01SDTM":"2020-12-23 03:12:22","AP01EDTM":"2021-02-18 22:06:37","AP02SDTM":"2021-02-18 22:06:37","AP02EDTM":"2022-02-19 04:06:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":424,"DCSREAS":"DEATH","DTHDT":"2022-03-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":33,"LDDTHGR1":">30","LSTALVDT":"2022-03-24","DTHADY":455,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5494,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.85577,"AVALU":"mg/L","BASE2":8.80031,"BASE":9.9414,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.94454,"PCHG2":-10.73298,"CHG":-2.08562,"PCHG":-20.97917,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-03-29 03:12:22","ADY":96,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-17-id-211","SUBJID":"id-211","SITEID":"GBR-17","AGE":62,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-17","INVNAM":"Dr. GBR-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":3.72545,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-23 03:12:22","TRTEDTM":"2022-02-19 04:06:37","TRT01SDTM":"2020-12-23 03:12:22","TRT01EDTM":"2021-02-18 22:06:37","TRT02SDTM":"2021-02-18 22:06:37","TRT02EDTM":"2022-02-19 04:06:37","AP01SDTM":"2020-12-23 03:12:22","AP01EDTM":"2021-02-18 22:06:37","AP02SDTM":"2021-02-18 22:06:37","AP02EDTM":"2022-02-19 04:06:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":424,"DCSREAS":"DEATH","DTHDT":"2022-03-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":33,"LDDTHGR1":">30","LSTALVDT":"2022-03-24","DTHADY":455,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5674,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.53114,"AVALU":"mg/L","BASE2":8.80031,"BASE":9.9414,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.26917,"PCHG2":-14.42187,"CHG":-2.41026,"PCHG":-24.24464,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-06-02 03:12:22","ADY":161,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-17-id-211","SUBJID":"id-211","SITEID":"GBR-17","AGE":62,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-17","INVNAM":"Dr. GBR-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":3.72545,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-23 03:12:22","TRTEDTM":"2022-02-19 04:06:37","TRT01SDTM":"2020-12-23 03:12:22","TRT01EDTM":"2021-02-18 22:06:37","TRT02SDTM":"2021-02-18 22:06:37","TRT02EDTM":"2022-02-19 04:06:37","AP01SDTM":"2020-12-23 03:12:22","AP01EDTM":"2021-02-18 22:06:37","AP02SDTM":"2021-02-18 22:06:37","AP02EDTM":"2022-02-19 04:06:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":424,"DCSREAS":"DEATH","DTHDT":"2022-03-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":33,"LDDTHGR1":">30","LSTALVDT":"2022-03-24","DTHADY":455,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3810,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.12738,"AVALU":"mg/L","BASE2":8.80031,"BASE":9.9414,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.32707,"PCHG2":3.7166,"CHG":-0.81401,"PCHG":-8.18812,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-09 03:12:22","ADY":168,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-17-id-211","SUBJID":"id-211","SITEID":"GBR-17","AGE":62,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-17","INVNAM":"Dr. GBR-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":3.72545,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-23 03:12:22","TRTEDTM":"2022-02-19 04:06:37","TRT01SDTM":"2020-12-23 03:12:22","TRT01EDTM":"2021-02-18 22:06:37","TRT02SDTM":"2021-02-18 22:06:37","TRT02EDTM":"2022-02-19 04:06:37","AP01SDTM":"2020-12-23 03:12:22","AP01EDTM":"2021-02-18 22:06:37","AP02SDTM":"2021-02-18 22:06:37","AP02EDTM":"2022-02-19 04:06:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":424,"DCSREAS":"DEATH","DTHDT":"2022-03-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":33,"LDDTHGR1":">30","LSTALVDT":"2022-03-24","DTHADY":455,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5281,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.41276,"AVALU":"mg/L","BASE2":8.80031,"BASE":9.9414,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.38755,"PCHG2":-15.7671,"CHG":-2.52864,"PCHG":-25.43546,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-01-17 03:12:22","ADY":390,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-17-id-211","SUBJID":"id-211","SITEID":"GBR-17","AGE":62,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-17","INVNAM":"Dr. GBR-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":3.72545,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-23 03:12:22","TRTEDTM":"2022-02-19 04:06:37","TRT01SDTM":"2020-12-23 03:12:22","TRT01EDTM":"2021-02-18 22:06:37","TRT02SDTM":"2021-02-18 22:06:37","TRT02EDTM":"2022-02-19 04:06:37","AP01SDTM":"2020-12-23 03:12:22","AP01EDTM":"2021-02-18 22:06:37","AP02SDTM":"2021-02-18 22:06:37","AP02EDTM":"2022-02-19 04:06:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":424,"DCSREAS":"DEATH","DTHDT":"2022-03-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":33,"LDDTHGR1":">30","LSTALVDT":"2022-03-24","DTHADY":455,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5632,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.48684,"AVALU":"mg/L","BASE2":8.80031,"BASE":9.9414,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.31347,"PCHG2":-3.56204,"CHG":-1.45456,"PCHG":-14.63132,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-02 03:12:22","ADY":406,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-17-id-211","SUBJID":"id-211","SITEID":"GBR-17","AGE":62,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-17","INVNAM":"Dr. GBR-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":3.72545,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-23 03:12:22","TRTEDTM":"2022-02-19 04:06:37","TRT01SDTM":"2020-12-23 03:12:22","TRT01EDTM":"2021-02-18 22:06:37","TRT02SDTM":"2021-02-18 22:06:37","TRT02EDTM":"2022-02-19 04:06:37","AP01SDTM":"2020-12-23 03:12:22","AP01EDTM":"2021-02-18 22:06:37","AP02SDTM":"2021-02-18 22:06:37","AP02EDTM":"2022-02-19 04:06:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":424,"DCSREAS":"DEATH","DTHDT":"2022-03-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":33,"LDDTHGR1":">30","LSTALVDT":"2022-03-24","DTHADY":455,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6390,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79488,"AVALU":"g/L","BASE2":2.79488,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-12-25 03:12:22","ADY":2,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-17-id-211","SUBJID":"id-211","SITEID":"GBR-17","AGE":62,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-17","INVNAM":"Dr. GBR-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":3.72545,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-23 03:12:22","TRTEDTM":"2022-02-19 04:06:37","TRT01SDTM":"2020-12-23 03:12:22","TRT01EDTM":"2021-02-18 22:06:37","TRT02SDTM":"2021-02-18 22:06:37","TRT02EDTM":"2022-02-19 04:06:37","AP01SDTM":"2020-12-23 03:12:22","AP01EDTM":"2021-02-18 22:06:37","AP02SDTM":"2021-02-18 22:06:37","AP02EDTM":"2022-02-19 04:06:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":424,"DCSREAS":"DEATH","DTHDT":"2022-03-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":33,"LDDTHGR1":">30","LSTALVDT":"2022-03-24","DTHADY":455,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1372,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.09881,"AVALU":"g/L","BASE2":2.79488,"BASE":3.09881,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.30393,"PCHG2":10.87447,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2021-03-06 03:12:22","ADY":73,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-17-id-211","SUBJID":"id-211","SITEID":"GBR-17","AGE":62,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-17","INVNAM":"Dr. GBR-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":3.72545,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-23 03:12:22","TRTEDTM":"2022-02-19 04:06:37","TRT01SDTM":"2020-12-23 03:12:22","TRT01EDTM":"2021-02-18 22:06:37","TRT02SDTM":"2021-02-18 22:06:37","TRT02EDTM":"2022-02-19 04:06:37","AP01SDTM":"2020-12-23 03:12:22","AP01EDTM":"2021-02-18 22:06:37","AP02SDTM":"2021-02-18 22:06:37","AP02EDTM":"2022-02-19 04:06:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":424,"DCSREAS":"DEATH","DTHDT":"2022-03-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":33,"LDDTHGR1":">30","LSTALVDT":"2022-03-24","DTHADY":455,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7616,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90617,"AVALU":"g/L","BASE2":2.79488,"BASE":3.09881,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11129,"PCHG2":3.98196,"CHG":-0.19264,"PCHG":-6.2165,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-03-29 03:12:22","ADY":96,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-17-id-211","SUBJID":"id-211","SITEID":"GBR-17","AGE":62,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-17","INVNAM":"Dr. GBR-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":3.72545,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-23 03:12:22","TRTEDTM":"2022-02-19 04:06:37","TRT01SDTM":"2020-12-23 03:12:22","TRT01EDTM":"2021-02-18 22:06:37","TRT02SDTM":"2021-02-18 22:06:37","TRT02EDTM":"2022-02-19 04:06:37","AP01SDTM":"2020-12-23 03:12:22","AP01EDTM":"2021-02-18 22:06:37","AP02SDTM":"2021-02-18 22:06:37","AP02EDTM":"2022-02-19 04:06:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":424,"DCSREAS":"DEATH","DTHDT":"2022-03-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":33,"LDDTHGR1":">30","LSTALVDT":"2022-03-24","DTHADY":455,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4220,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89574,"AVALU":"g/L","BASE2":2.79488,"BASE":3.09881,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10086,"PCHG2":3.60886,"CHG":-0.20307,"PCHG":-6.55301,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-06-02 03:12:22","ADY":161,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-17-id-211","SUBJID":"id-211","SITEID":"GBR-17","AGE":62,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-17","INVNAM":"Dr. GBR-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":3.72545,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-23 03:12:22","TRTEDTM":"2022-02-19 04:06:37","TRT01SDTM":"2020-12-23 03:12:22","TRT01EDTM":"2021-02-18 22:06:37","TRT02SDTM":"2021-02-18 22:06:37","TRT02EDTM":"2022-02-19 04:06:37","AP01SDTM":"2020-12-23 03:12:22","AP01EDTM":"2021-02-18 22:06:37","AP02SDTM":"2021-02-18 22:06:37","AP02EDTM":"2022-02-19 04:06:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":424,"DCSREAS":"DEATH","DTHDT":"2022-03-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":33,"LDDTHGR1":">30","LSTALVDT":"2022-03-24","DTHADY":455,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7795,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95632,"AVALU":"g/L","BASE2":2.79488,"BASE":3.09881,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16143,"PCHG2":5.77609,"CHG":-0.14249,"PCHG":-4.59833,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-06-09 03:12:22","ADY":168,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-17-id-211","SUBJID":"id-211","SITEID":"GBR-17","AGE":62,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-17","INVNAM":"Dr. GBR-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":3.72545,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-23 03:12:22","TRTEDTM":"2022-02-19 04:06:37","TRT01SDTM":"2020-12-23 03:12:22","TRT01EDTM":"2021-02-18 22:06:37","TRT02SDTM":"2021-02-18 22:06:37","TRT02EDTM":"2022-02-19 04:06:37","AP01SDTM":"2020-12-23 03:12:22","AP01EDTM":"2021-02-18 22:06:37","AP02SDTM":"2021-02-18 22:06:37","AP02EDTM":"2022-02-19 04:06:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":424,"DCSREAS":"DEATH","DTHDT":"2022-03-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":33,"LDDTHGR1":">30","LSTALVDT":"2022-03-24","DTHADY":455,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1634,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95325,"AVALU":"g/L","BASE2":2.79488,"BASE":3.09881,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15837,"PCHG2":5.66654,"CHG":-0.14556,"PCHG":-4.69714,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-01-17 03:12:22","ADY":390,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-17-id-211","SUBJID":"id-211","SITEID":"GBR-17","AGE":62,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"Y","INVID":"INV ID GBR-17","INVNAM":"Dr. GBR-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Europe","STRATA1":"A","STRATA2":"S1","BMRKR1":3.72545,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-20","TRTSDTM":"2020-12-23 03:12:22","TRTEDTM":"2022-02-19 04:06:37","TRT01SDTM":"2020-12-23 03:12:22","TRT01EDTM":"2021-02-18 22:06:37","TRT02SDTM":"2021-02-18 22:06:37","TRT02EDTM":"2022-02-19 04:06:37","AP01SDTM":"2020-12-23 03:12:22","AP01EDTM":"2021-02-18 22:06:37","AP02SDTM":"2021-02-18 22:06:37","AP02EDTM":"2022-02-19 04:06:37","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":424,"DCSREAS":"DEATH","DTHDT":"2022-03-24","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":33,"LDDTHGR1":">30","LSTALVDT":"2022-03-24","DTHADY":455,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7817,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04214,"AVALU":"g/L","BASE2":2.79488,"BASE":3.09881,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.24726,"PCHG2":8.84686,"CHG":-0.05667,"PCHG":-1.82874,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"1","BTOXGR":"3","ADTM":"2022-02-02 03:12:22","ADY":406,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-6-id-111","SUBJID":"id-111","SITEID":"GBR-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-6","INVNAM":"Dr. GBR-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.67011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 00:29:19","TRTEDTM":"2022-07-28 18:29:19","TRT01SDTM":"2019-07-29 00:29:19","TRT01EDTM":"2021-07-28 12:29:19","TRT02SDTM":"2021-07-28 12:29:19","TRT02EDTM":"2022-07-28 18:29:19","AP01SDTM":"2019-07-29 00:29:19","AP01EDTM":"2021-07-28 12:29:19","AP02SDTM":"2021-07-28 12:29:19","AP02EDTM":"2022-07-28 18:29:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4864,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.91446,"AVALU":"U/L","BASE2":20.91446,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-17 00:29:19","ADY":263,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-6-id-111","SUBJID":"id-111","SITEID":"GBR-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-6","INVNAM":"Dr. GBR-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.67011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 00:29:19","TRTEDTM":"2022-07-28 18:29:19","TRT01SDTM":"2019-07-29 00:29:19","TRT01EDTM":"2021-07-28 12:29:19","TRT02SDTM":"2021-07-28 12:29:19","TRT02EDTM":"2022-07-28 18:29:19","AP01SDTM":"2019-07-29 00:29:19","AP01EDTM":"2021-07-28 12:29:19","AP02SDTM":"2021-07-28 12:29:19","AP02EDTM":"2022-07-28 18:29:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1792,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.26449,"AVALU":"U/L","BASE2":20.91446,"BASE":30.26449,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":9.35003,"PCHG2":44.70605,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-08 00:29:19","ADY":376,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-6-id-111","SUBJID":"id-111","SITEID":"GBR-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-6","INVNAM":"Dr. GBR-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.67011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 00:29:19","TRTEDTM":"2022-07-28 18:29:19","TRT01SDTM":"2019-07-29 00:29:19","TRT01EDTM":"2021-07-28 12:29:19","TRT02SDTM":"2021-07-28 12:29:19","TRT02EDTM":"2022-07-28 18:29:19","AP01SDTM":"2019-07-29 00:29:19","AP01EDTM":"2021-07-28 12:29:19","AP02SDTM":"2021-07-28 12:29:19","AP02EDTM":"2022-07-28 18:29:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7223,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.14099,"AVALU":"U/L","BASE2":20.91446,"BASE":30.26449,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.22652,"PCHG2":10.64586,"CHG":-7.12351,"PCHG":-23.53751,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-04 00:29:19","ADY":525,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-6-id-111","SUBJID":"id-111","SITEID":"GBR-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-6","INVNAM":"Dr. GBR-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.67011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 00:29:19","TRTEDTM":"2022-07-28 18:29:19","TRT01SDTM":"2019-07-29 00:29:19","TRT01EDTM":"2021-07-28 12:29:19","TRT02SDTM":"2021-07-28 12:29:19","TRT02EDTM":"2022-07-28 18:29:19","AP01SDTM":"2019-07-29 00:29:19","AP01EDTM":"2021-07-28 12:29:19","AP02SDTM":"2021-07-28 12:29:19","AP02EDTM":"2022-07-28 18:29:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7543,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.61613,"AVALU":"U/L","BASE2":20.91446,"BASE":30.26449,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.29833,"PCHG2":-77.92851,"CHG":-25.64836,"PCHG":-84.74736,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-03-09 00:29:19","ADY":589,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-6-id-111","SUBJID":"id-111","SITEID":"GBR-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-6","INVNAM":"Dr. GBR-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.67011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 00:29:19","TRTEDTM":"2022-07-28 18:29:19","TRT01SDTM":"2019-07-29 00:29:19","TRT01EDTM":"2021-07-28 12:29:19","TRT02SDTM":"2021-07-28 12:29:19","TRT02EDTM":"2022-07-28 18:29:19","AP01SDTM":"2019-07-29 00:29:19","AP01EDTM":"2021-07-28 12:29:19","AP02SDTM":"2021-07-28 12:29:19","AP02EDTM":"2022-07-28 18:29:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3373,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.14582,"AVALU":"U/L","BASE2":20.91446,"BASE":30.26449,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.23135,"PCHG2":44.13862,"CHG":-0.11868,"PCHG":-0.39213,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-02 00:29:19","ADY":735,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-6-id-111","SUBJID":"id-111","SITEID":"GBR-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-6","INVNAM":"Dr. GBR-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.67011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 00:29:19","TRTEDTM":"2022-07-28 18:29:19","TRT01SDTM":"2019-07-29 00:29:19","TRT01EDTM":"2021-07-28 12:29:19","TRT02SDTM":"2021-07-28 12:29:19","TRT02EDTM":"2022-07-28 18:29:19","AP01SDTM":"2019-07-29 00:29:19","AP01EDTM":"2021-07-28 12:29:19","AP02SDTM":"2021-07-28 12:29:19","AP02EDTM":"2022-07-28 18:29:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5535,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.05695,"AVALU":"U/L","BASE2":20.91446,"BASE":30.26449,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.85751,"PCHG2":-32.78838,"CHG":-16.20754,"PCHG":-53.553,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-10 00:29:19","ADY":743,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-6-id-111","SUBJID":"id-111","SITEID":"GBR-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-6","INVNAM":"Dr. GBR-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.67011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 00:29:19","TRTEDTM":"2022-07-28 18:29:19","TRT01SDTM":"2019-07-29 00:29:19","TRT01EDTM":"2021-07-28 12:29:19","TRT02SDTM":"2021-07-28 12:29:19","TRT02EDTM":"2022-07-28 18:29:19","AP01SDTM":"2019-07-29 00:29:19","AP01EDTM":"2021-07-28 12:29:19","AP02SDTM":"2021-07-28 12:29:19","AP02EDTM":"2022-07-28 18:29:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":15,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.40614,"AVALU":"U/L","BASE2":20.91446,"BASE":30.26449,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-18.50833,"PCHG2":-88.49535,"CHG":-27.85836,"PCHG":-92.04964,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-03-08 00:29:19","ADY":953,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-6-id-111","SUBJID":"id-111","SITEID":"GBR-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-6","INVNAM":"Dr. GBR-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.67011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 00:29:19","TRTEDTM":"2022-07-28 18:29:19","TRT01SDTM":"2019-07-29 00:29:19","TRT01EDTM":"2021-07-28 12:29:19","TRT02SDTM":"2021-07-28 12:29:19","TRT02EDTM":"2022-07-28 18:29:19","AP01SDTM":"2019-07-29 00:29:19","AP01EDTM":"2021-07-28 12:29:19","AP02SDTM":"2021-07-28 12:29:19","AP02EDTM":"2022-07-28 18:29:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6746,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.89415,"AVALU":"mg/L","BASE2":9.89415,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-17 00:29:19","ADY":263,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-6-id-111","SUBJID":"id-111","SITEID":"GBR-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-6","INVNAM":"Dr. GBR-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.67011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 00:29:19","TRTEDTM":"2022-07-28 18:29:19","TRT01SDTM":"2019-07-29 00:29:19","TRT01EDTM":"2021-07-28 12:29:19","TRT02SDTM":"2021-07-28 12:29:19","TRT02EDTM":"2022-07-28 18:29:19","AP01SDTM":"2019-07-29 00:29:19","AP01EDTM":"2021-07-28 12:29:19","AP02SDTM":"2021-07-28 12:29:19","AP02EDTM":"2022-07-28 18:29:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5532,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.6418,"AVALU":"mg/L","BASE2":9.89415,"BASE":8.6418,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.25235,"PCHG2":-12.65749,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-08 00:29:19","ADY":376,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-6-id-111","SUBJID":"id-111","SITEID":"GBR-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-6","INVNAM":"Dr. GBR-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.67011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 00:29:19","TRTEDTM":"2022-07-28 18:29:19","TRT01SDTM":"2019-07-29 00:29:19","TRT01EDTM":"2021-07-28 12:29:19","TRT02SDTM":"2021-07-28 12:29:19","TRT02EDTM":"2022-07-28 18:29:19","AP01SDTM":"2019-07-29 00:29:19","AP01EDTM":"2021-07-28 12:29:19","AP02SDTM":"2021-07-28 12:29:19","AP02EDTM":"2022-07-28 18:29:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5855,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.19492,"AVALU":"mg/L","BASE2":9.89415,"BASE":8.6418,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.69923,"PCHG2":-17.17405,"CHG":-0.44687,"PCHG":-5.17109,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-04 00:29:19","ADY":525,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-6-id-111","SUBJID":"id-111","SITEID":"GBR-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-6","INVNAM":"Dr. GBR-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.67011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 00:29:19","TRTEDTM":"2022-07-28 18:29:19","TRT01SDTM":"2019-07-29 00:29:19","TRT01EDTM":"2021-07-28 12:29:19","TRT02SDTM":"2021-07-28 12:29:19","TRT02EDTM":"2022-07-28 18:29:19","AP01SDTM":"2019-07-29 00:29:19","AP01EDTM":"2021-07-28 12:29:19","AP02SDTM":"2021-07-28 12:29:19","AP02EDTM":"2022-07-28 18:29:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2980,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.7067,"AVALU":"mg/L","BASE2":9.89415,"BASE":8.6418,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18745,"PCHG2":-1.89452,"CHG":1.0649,"PCHG":12.32272,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-09 00:29:19","ADY":589,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-6-id-111","SUBJID":"id-111","SITEID":"GBR-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-6","INVNAM":"Dr. GBR-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.67011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 00:29:19","TRTEDTM":"2022-07-28 18:29:19","TRT01SDTM":"2019-07-29 00:29:19","TRT01EDTM":"2021-07-28 12:29:19","TRT02SDTM":"2021-07-28 12:29:19","TRT02EDTM":"2022-07-28 18:29:19","AP01SDTM":"2019-07-29 00:29:19","AP01EDTM":"2021-07-28 12:29:19","AP02SDTM":"2021-07-28 12:29:19","AP02EDTM":"2022-07-28 18:29:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4450,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.70771,"AVALU":"mg/L","BASE2":9.89415,"BASE":8.6418,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.18643,"PCHG2":-11.99128,"CHG":0.06592,"PCHG":0.76276,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-02 00:29:19","ADY":735,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-6-id-111","SUBJID":"id-111","SITEID":"GBR-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-6","INVNAM":"Dr. GBR-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.67011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 00:29:19","TRTEDTM":"2022-07-28 18:29:19","TRT01SDTM":"2019-07-29 00:29:19","TRT01EDTM":"2021-07-28 12:29:19","TRT02SDTM":"2021-07-28 12:29:19","TRT02EDTM":"2022-07-28 18:29:19","AP01SDTM":"2019-07-29 00:29:19","AP01EDTM":"2021-07-28 12:29:19","AP02SDTM":"2021-07-28 12:29:19","AP02EDTM":"2022-07-28 18:29:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3858,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.32636,"AVALU":"mg/L","BASE2":9.89415,"BASE":8.6418,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.43221,"PCHG2":4.36835,"CHG":1.68456,"PCHG":19.49319,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-08-10 00:29:19","ADY":743,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-6-id-111","SUBJID":"id-111","SITEID":"GBR-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-6","INVNAM":"Dr. GBR-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.67011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 00:29:19","TRTEDTM":"2022-07-28 18:29:19","TRT01SDTM":"2019-07-29 00:29:19","TRT01EDTM":"2021-07-28 12:29:19","TRT02SDTM":"2021-07-28 12:29:19","TRT02EDTM":"2022-07-28 18:29:19","AP01SDTM":"2019-07-29 00:29:19","AP01EDTM":"2021-07-28 12:29:19","AP02SDTM":"2021-07-28 12:29:19","AP02EDTM":"2022-07-28 18:29:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4051,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.21182,"AVALU":"mg/L","BASE2":9.89415,"BASE":8.6418,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.31768,"PCHG2":3.21074,"CHG":1.57003,"PCHG":18.16782,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2022-03-08 00:29:19","ADY":953,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-6-id-111","SUBJID":"id-111","SITEID":"GBR-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-6","INVNAM":"Dr. GBR-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.67011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 00:29:19","TRTEDTM":"2022-07-28 18:29:19","TRT01SDTM":"2019-07-29 00:29:19","TRT01EDTM":"2021-07-28 12:29:19","TRT02SDTM":"2021-07-28 12:29:19","TRT02EDTM":"2022-07-28 18:29:19","AP01SDTM":"2019-07-29 00:29:19","AP01EDTM":"2021-07-28 12:29:19","AP02SDTM":"2021-07-28 12:29:19","AP02EDTM":"2022-07-28 18:29:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6414,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90614,"AVALU":"g/L","BASE2":2.90614,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-17 00:29:19","ADY":263,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-6-id-111","SUBJID":"id-111","SITEID":"GBR-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-6","INVNAM":"Dr. GBR-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.67011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 00:29:19","TRTEDTM":"2022-07-28 18:29:19","TRT01SDTM":"2019-07-29 00:29:19","TRT01EDTM":"2021-07-28 12:29:19","TRT02SDTM":"2021-07-28 12:29:19","TRT02EDTM":"2022-07-28 18:29:19","AP01SDTM":"2019-07-29 00:29:19","AP01EDTM":"2021-07-28 12:29:19","AP02SDTM":"2021-07-28 12:29:19","AP02EDTM":"2022-07-28 18:29:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7511,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96684,"AVALU":"g/L","BASE2":2.90614,"BASE":2.96684,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.0607,"PCHG2":2.08866,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-08 00:29:19","ADY":376,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-6-id-111","SUBJID":"id-111","SITEID":"GBR-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-6","INVNAM":"Dr. GBR-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.67011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 00:29:19","TRTEDTM":"2022-07-28 18:29:19","TRT01SDTM":"2019-07-29 00:29:19","TRT01EDTM":"2021-07-28 12:29:19","TRT02SDTM":"2021-07-28 12:29:19","TRT02EDTM":"2022-07-28 18:29:19","AP01SDTM":"2019-07-29 00:29:19","AP01EDTM":"2021-07-28 12:29:19","AP02SDTM":"2021-07-28 12:29:19","AP02EDTM":"2022-07-28 18:29:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":513,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76371,"AVALU":"g/L","BASE2":2.90614,"BASE":2.96684,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14243,"PCHG2":-4.90104,"CHG":-0.20313,"PCHG":-6.84669,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-04 00:29:19","ADY":525,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-6-id-111","SUBJID":"id-111","SITEID":"GBR-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-6","INVNAM":"Dr. GBR-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.67011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 00:29:19","TRTEDTM":"2022-07-28 18:29:19","TRT01SDTM":"2019-07-29 00:29:19","TRT01EDTM":"2021-07-28 12:29:19","TRT02SDTM":"2021-07-28 12:29:19","TRT02EDTM":"2022-07-28 18:29:19","AP01SDTM":"2019-07-29 00:29:19","AP01EDTM":"2021-07-28 12:29:19","AP02SDTM":"2021-07-28 12:29:19","AP02EDTM":"2022-07-28 18:29:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4383,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75084,"AVALU":"g/L","BASE2":2.90614,"BASE":2.96684,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1553,"PCHG2":-5.34392,"CHG":-0.216,"PCHG":-7.28051,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-09 00:29:19","ADY":589,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-6-id-111","SUBJID":"id-111","SITEID":"GBR-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-6","INVNAM":"Dr. GBR-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.67011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 00:29:19","TRTEDTM":"2022-07-28 18:29:19","TRT01SDTM":"2019-07-29 00:29:19","TRT01EDTM":"2021-07-28 12:29:19","TRT02SDTM":"2021-07-28 12:29:19","TRT02EDTM":"2022-07-28 18:29:19","AP01SDTM":"2019-07-29 00:29:19","AP01EDTM":"2021-07-28 12:29:19","AP02SDTM":"2021-07-28 12:29:19","AP02EDTM":"2022-07-28 18:29:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2412,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.12468,"AVALU":"g/L","BASE2":2.90614,"BASE":2.96684,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.21853,"PCHG2":7.51976,"CHG":0.15784,"PCHG":5.31999,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-08-02 00:29:19","ADY":735,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-6-id-111","SUBJID":"id-111","SITEID":"GBR-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-6","INVNAM":"Dr. GBR-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.67011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 00:29:19","TRTEDTM":"2022-07-28 18:29:19","TRT01SDTM":"2019-07-29 00:29:19","TRT01EDTM":"2021-07-28 12:29:19","TRT02SDTM":"2021-07-28 12:29:19","TRT02EDTM":"2022-07-28 18:29:19","AP01SDTM":"2019-07-29 00:29:19","AP01EDTM":"2021-07-28 12:29:19","AP02SDTM":"2021-07-28 12:29:19","AP02EDTM":"2022-07-28 18:29:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2414,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79394,"AVALU":"g/L","BASE2":2.90614,"BASE":2.96684,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1122,"PCHG2":-3.86083,"CHG":-0.1729,"PCHG":-5.82776,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-10 00:29:19","ADY":743,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-GBR-6-id-111","SUBJID":"id-111","SITEID":"GBR-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"GBR","DTHFL":"N","INVID":"INV ID GBR-6","INVNAM":"Dr. GBR-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Europe","STRATA1":"B","STRATA2":"S2","BMRKR1":4.67011,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 00:29:19","TRTEDTM":"2022-07-28 18:29:19","TRT01SDTM":"2019-07-29 00:29:19","TRT01EDTM":"2021-07-28 12:29:19","TRT02SDTM":"2021-07-28 12:29:19","TRT02EDTM":"2022-07-28 18:29:19","AP01SDTM":"2019-07-29 00:29:19","AP01EDTM":"2021-07-28 12:29:19","AP02SDTM":"2021-07-28 12:29:19","AP02EDTM":"2022-07-28 18:29:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-28","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7255,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7506,"AVALU":"g/L","BASE2":2.90614,"BASE":2.96684,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15554,"PCHG2":-5.35227,"CHG":-0.21624,"PCHG":-7.28869,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-08 00:29:19","ADY":953,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-21","SUBJID":"id-21","SITEID":"JPN-1","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":13.29869,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 23:27:24","TRTEDTM":"2023-11-18 17:27:24","TRT01SDTM":"2020-11-17 23:27:24","TRT01EDTM":"2022-11-18 11:27:24","TRT02SDTM":"2022-11-18 11:27:24","TRT02EDTM":"2023-11-18 17:27:24","AP01SDTM":"2020-11-17 23:27:24","AP01EDTM":"2022-11-18 11:27:24","AP02SDTM":"2022-11-18 11:27:24","AP02EDTM":"2023-11-18 17:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-11-30","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1197,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.07202,"AVALU":"U/L","BASE2":16.07202,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-08 23:27:24","ADY":83,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-21","SUBJID":"id-21","SITEID":"JPN-1","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":13.29869,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 23:27:24","TRTEDTM":"2023-11-18 17:27:24","TRT01SDTM":"2020-11-17 23:27:24","TRT01EDTM":"2022-11-18 11:27:24","TRT02SDTM":"2022-11-18 11:27:24","TRT02EDTM":"2023-11-18 17:27:24","AP01SDTM":"2020-11-17 23:27:24","AP01EDTM":"2022-11-18 11:27:24","AP02SDTM":"2022-11-18 11:27:24","AP02EDTM":"2023-11-18 17:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-11-30","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7400,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.14624,"AVALU":"U/L","BASE2":16.07202,"BASE":21.14624,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":5.07423,"PCHG2":31.57181,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-11 23:27:24","ADY":175,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-21","SUBJID":"id-21","SITEID":"JPN-1","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":13.29869,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 23:27:24","TRTEDTM":"2023-11-18 17:27:24","TRT01SDTM":"2020-11-17 23:27:24","TRT01EDTM":"2022-11-18 11:27:24","TRT02SDTM":"2022-11-18 11:27:24","TRT02EDTM":"2023-11-18 17:27:24","AP01SDTM":"2020-11-17 23:27:24","AP01EDTM":"2022-11-18 11:27:24","AP02SDTM":"2022-11-18 11:27:24","AP02EDTM":"2023-11-18 17:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-11-30","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6449,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.81749,"AVALU":"U/L","BASE2":16.07202,"BASE":21.14624,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.74548,"PCHG2":54.41432,"CHG":3.67125,"PCHG":17.36125,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-04 23:27:24","ADY":503,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-21","SUBJID":"id-21","SITEID":"JPN-1","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":13.29869,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 23:27:24","TRTEDTM":"2023-11-18 17:27:24","TRT01SDTM":"2020-11-17 23:27:24","TRT01EDTM":"2022-11-18 11:27:24","TRT02SDTM":"2022-11-18 11:27:24","TRT02EDTM":"2023-11-18 17:27:24","AP01SDTM":"2020-11-17 23:27:24","AP01EDTM":"2022-11-18 11:27:24","AP02SDTM":"2022-11-18 11:27:24","AP02EDTM":"2023-11-18 17:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-11-30","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3695,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.22471,"AVALU":"U/L","BASE2":16.07202,"BASE":21.14624,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.84731,"PCHG2":-17.71595,"CHG":-7.92154,"PCHG":-37.46073,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-05 23:27:24","ADY":534,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-21","SUBJID":"id-21","SITEID":"JPN-1","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":13.29869,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 23:27:24","TRTEDTM":"2023-11-18 17:27:24","TRT01SDTM":"2020-11-17 23:27:24","TRT01EDTM":"2022-11-18 11:27:24","TRT02SDTM":"2022-11-18 11:27:24","TRT02EDTM":"2023-11-18 17:27:24","AP01SDTM":"2020-11-17 23:27:24","AP01EDTM":"2022-11-18 11:27:24","AP02SDTM":"2022-11-18 11:27:24","AP02EDTM":"2023-11-18 17:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-11-30","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2245,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.89187,"AVALU":"U/L","BASE2":16.07202,"BASE":21.14624,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.18015,"PCHG2":-88.22879,"CHG":-19.25437,"PCHG":-91.0534,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-06-14 23:27:24","ADY":574,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-21","SUBJID":"id-21","SITEID":"JPN-1","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":13.29869,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 23:27:24","TRTEDTM":"2023-11-18 17:27:24","TRT01SDTM":"2020-11-17 23:27:24","TRT01EDTM":"2022-11-18 11:27:24","TRT02SDTM":"2022-11-18 11:27:24","TRT02EDTM":"2023-11-18 17:27:24","AP01SDTM":"2020-11-17 23:27:24","AP01EDTM":"2022-11-18 11:27:24","AP02SDTM":"2022-11-18 11:27:24","AP02EDTM":"2023-11-18 17:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-11-30","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3805,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.25554,"AVALU":"U/L","BASE2":16.07202,"BASE":21.14624,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.18353,"PCHG2":113.13782,"CHG":13.1093,"PCHG":61.99353,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-05 23:27:24","ADY":718,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-21","SUBJID":"id-21","SITEID":"JPN-1","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":13.29869,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 23:27:24","TRTEDTM":"2023-11-18 17:27:24","TRT01SDTM":"2020-11-17 23:27:24","TRT01EDTM":"2022-11-18 11:27:24","TRT02SDTM":"2022-11-18 11:27:24","TRT02EDTM":"2023-11-18 17:27:24","AP01SDTM":"2020-11-17 23:27:24","AP01EDTM":"2022-11-18 11:27:24","AP02SDTM":"2022-11-18 11:27:24","AP02EDTM":"2023-11-18 17:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-11-30","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1867,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.33274,"AVALU":"U/L","BASE2":16.07202,"BASE":21.14624,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.26072,"PCHG2":51.39818,"CHG":3.1865,"PCHG":15.06886,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-26 23:27:24","ADY":1012,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-21","SUBJID":"id-21","SITEID":"JPN-1","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":13.29869,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 23:27:24","TRTEDTM":"2023-11-18 17:27:24","TRT01SDTM":"2020-11-17 23:27:24","TRT01EDTM":"2022-11-18 11:27:24","TRT02SDTM":"2022-11-18 11:27:24","TRT02EDTM":"2023-11-18 17:27:24","AP01SDTM":"2020-11-17 23:27:24","AP01EDTM":"2022-11-18 11:27:24","AP02SDTM":"2022-11-18 11:27:24","AP02EDTM":"2023-11-18 17:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-11-30","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4144,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.5954,"AVALU":"mg/L","BASE2":9.5954,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-02-08 23:27:24","ADY":83,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-21","SUBJID":"id-21","SITEID":"JPN-1","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":13.29869,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 23:27:24","TRTEDTM":"2023-11-18 17:27:24","TRT01SDTM":"2020-11-17 23:27:24","TRT01EDTM":"2022-11-18 11:27:24","TRT02SDTM":"2022-11-18 11:27:24","TRT02EDTM":"2023-11-18 17:27:24","AP01SDTM":"2020-11-17 23:27:24","AP01EDTM":"2022-11-18 11:27:24","AP02SDTM":"2022-11-18 11:27:24","AP02EDTM":"2023-11-18 17:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-11-30","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1726,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.62726,"AVALU":"mg/L","BASE2":9.5954,"BASE":11.62726,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.03187,"PCHG2":21.17543,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2021-05-11 23:27:24","ADY":175,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-21","SUBJID":"id-21","SITEID":"JPN-1","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":13.29869,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 23:27:24","TRTEDTM":"2023-11-18 17:27:24","TRT01SDTM":"2020-11-17 23:27:24","TRT01EDTM":"2022-11-18 11:27:24","TRT02SDTM":"2022-11-18 11:27:24","TRT02EDTM":"2023-11-18 17:27:24","AP01SDTM":"2020-11-17 23:27:24","AP01EDTM":"2022-11-18 11:27:24","AP02SDTM":"2022-11-18 11:27:24","AP02EDTM":"2023-11-18 17:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-11-30","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8088,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.06629,"AVALU":"mg/L","BASE2":9.5954,"BASE":11.62726,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.5291,"PCHG2":-5.51414,"CHG":-2.56097,"PCHG":-22.02556,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2022-04-04 23:27:24","ADY":503,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-21","SUBJID":"id-21","SITEID":"JPN-1","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":13.29869,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 23:27:24","TRTEDTM":"2023-11-18 17:27:24","TRT01SDTM":"2020-11-17 23:27:24","TRT01EDTM":"2022-11-18 11:27:24","TRT02SDTM":"2022-11-18 11:27:24","TRT02EDTM":"2023-11-18 17:27:24","AP01SDTM":"2020-11-17 23:27:24","AP01EDTM":"2022-11-18 11:27:24","AP02SDTM":"2022-11-18 11:27:24","AP02EDTM":"2023-11-18 17:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-11-30","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6057,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.83892,"AVALU":"mg/L","BASE2":9.5954,"BASE":11.62726,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.75648,"PCHG2":-18.30545,"CHG":-3.78835,"PCHG":-32.58159,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-1","BTOXGR":"1","ADTM":"2022-05-05 23:27:24","ADY":534,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-21","SUBJID":"id-21","SITEID":"JPN-1","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":13.29869,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 23:27:24","TRTEDTM":"2023-11-18 17:27:24","TRT01SDTM":"2020-11-17 23:27:24","TRT01EDTM":"2022-11-18 11:27:24","TRT02SDTM":"2022-11-18 11:27:24","TRT02EDTM":"2023-11-18 17:27:24","AP01SDTM":"2020-11-17 23:27:24","AP01EDTM":"2022-11-18 11:27:24","AP02SDTM":"2022-11-18 11:27:24","AP02EDTM":"2023-11-18 17:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-11-30","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2362,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.46873,"AVALU":"mg/L","BASE2":9.5954,"BASE":11.62726,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12667,"PCHG2":-1.32009,"CHG":-2.15853,"PCHG":-18.56443,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2022-06-14 23:27:24","ADY":574,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-21","SUBJID":"id-21","SITEID":"JPN-1","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":13.29869,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 23:27:24","TRTEDTM":"2023-11-18 17:27:24","TRT01SDTM":"2020-11-17 23:27:24","TRT01EDTM":"2022-11-18 11:27:24","TRT02SDTM":"2022-11-18 11:27:24","TRT02EDTM":"2023-11-18 17:27:24","AP01SDTM":"2020-11-17 23:27:24","AP01EDTM":"2022-11-18 11:27:24","AP02SDTM":"2022-11-18 11:27:24","AP02EDTM":"2023-11-18 17:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-11-30","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5273,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.80233,"AVALU":"mg/L","BASE2":9.5954,"BASE":11.62726,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.20693,"PCHG2":12.57827,"CHG":-0.82493,"PCHG":-7.0948,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"4","BTOXGR":"1","ADTM":"2022-11-05 23:27:24","ADY":718,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-21","SUBJID":"id-21","SITEID":"JPN-1","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":13.29869,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 23:27:24","TRTEDTM":"2023-11-18 17:27:24","TRT01SDTM":"2020-11-17 23:27:24","TRT01EDTM":"2022-11-18 11:27:24","TRT02SDTM":"2022-11-18 11:27:24","TRT02EDTM":"2023-11-18 17:27:24","AP01SDTM":"2020-11-17 23:27:24","AP01EDTM":"2022-11-18 11:27:24","AP02SDTM":"2022-11-18 11:27:24","AP02EDTM":"2023-11-18 17:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-11-30","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5973,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.12765,"AVALU":"mg/L","BASE2":9.5954,"BASE":11.62726,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.46775,"PCHG2":-15.29635,"CHG":-3.49961,"PCHG":-30.09833,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2023-08-26 23:27:24","ADY":1012,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-21","SUBJID":"id-21","SITEID":"JPN-1","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":13.29869,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 23:27:24","TRTEDTM":"2023-11-18 17:27:24","TRT01SDTM":"2020-11-17 23:27:24","TRT01EDTM":"2022-11-18 11:27:24","TRT02SDTM":"2022-11-18 11:27:24","TRT02EDTM":"2023-11-18 17:27:24","AP01SDTM":"2020-11-17 23:27:24","AP01EDTM":"2022-11-18 11:27:24","AP02SDTM":"2022-11-18 11:27:24","AP02EDTM":"2023-11-18 17:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-11-30","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1732,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02443,"AVALU":"g/L","BASE2":3.02443,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-02-08 23:27:24","ADY":83,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-21","SUBJID":"id-21","SITEID":"JPN-1","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":13.29869,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 23:27:24","TRTEDTM":"2023-11-18 17:27:24","TRT01SDTM":"2020-11-17 23:27:24","TRT01EDTM":"2022-11-18 11:27:24","TRT02SDTM":"2022-11-18 11:27:24","TRT02EDTM":"2023-11-18 17:27:24","AP01SDTM":"2020-11-17 23:27:24","AP01EDTM":"2022-11-18 11:27:24","AP02SDTM":"2022-11-18 11:27:24","AP02EDTM":"2023-11-18 17:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-11-30","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1711,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88215,"AVALU":"g/L","BASE2":3.02443,"BASE":2.88215,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.14228,"PCHG2":-4.70444,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-11 23:27:24","ADY":175,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-21","SUBJID":"id-21","SITEID":"JPN-1","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":13.29869,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 23:27:24","TRTEDTM":"2023-11-18 17:27:24","TRT01SDTM":"2020-11-17 23:27:24","TRT01EDTM":"2022-11-18 11:27:24","TRT02SDTM":"2022-11-18 11:27:24","TRT02EDTM":"2023-11-18 17:27:24","AP01SDTM":"2020-11-17 23:27:24","AP01EDTM":"2022-11-18 11:27:24","AP02SDTM":"2022-11-18 11:27:24","AP02EDTM":"2023-11-18 17:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-11-30","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":851,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92261,"AVALU":"g/L","BASE2":3.02443,"BASE":2.88215,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10182,"PCHG2":-3.36643,"CHG":0.04047,"PCHG":1.40407,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-04 23:27:24","ADY":503,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-21","SUBJID":"id-21","SITEID":"JPN-1","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":13.29869,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 23:27:24","TRTEDTM":"2023-11-18 17:27:24","TRT01SDTM":"2020-11-17 23:27:24","TRT01EDTM":"2022-11-18 11:27:24","TRT02SDTM":"2022-11-18 11:27:24","TRT02EDTM":"2023-11-18 17:27:24","AP01SDTM":"2020-11-17 23:27:24","AP01EDTM":"2022-11-18 11:27:24","AP02SDTM":"2022-11-18 11:27:24","AP02EDTM":"2023-11-18 17:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-11-30","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5167,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99184,"AVALU":"g/L","BASE2":3.02443,"BASE":2.88215,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03259,"PCHG2":-1.0776,"CHG":0.10969,"PCHG":3.80589,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-05 23:27:24","ADY":534,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-21","SUBJID":"id-21","SITEID":"JPN-1","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":13.29869,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 23:27:24","TRTEDTM":"2023-11-18 17:27:24","TRT01SDTM":"2020-11-17 23:27:24","TRT01EDTM":"2022-11-18 11:27:24","TRT02SDTM":"2022-11-18 11:27:24","TRT02EDTM":"2023-11-18 17:27:24","AP01SDTM":"2020-11-17 23:27:24","AP01EDTM":"2022-11-18 11:27:24","AP02SDTM":"2022-11-18 11:27:24","AP02EDTM":"2023-11-18 17:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-11-30","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4729,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02532,"AVALU":"g/L","BASE2":3.02443,"BASE":2.88215,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00089,"PCHG2":0.02935,"CHG":0.14317,"PCHG":4.96749,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2022-06-14 23:27:24","ADY":574,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-21","SUBJID":"id-21","SITEID":"JPN-1","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":13.29869,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 23:27:24","TRTEDTM":"2023-11-18 17:27:24","TRT01SDTM":"2020-11-17 23:27:24","TRT01EDTM":"2022-11-18 11:27:24","TRT02SDTM":"2022-11-18 11:27:24","TRT02EDTM":"2023-11-18 17:27:24","AP01SDTM":"2020-11-17 23:27:24","AP01EDTM":"2022-11-18 11:27:24","AP02SDTM":"2022-11-18 11:27:24","AP02EDTM":"2023-11-18 17:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-11-30","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2557,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89379,"AVALU":"g/L","BASE2":3.02443,"BASE":2.88215,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13063,"PCHG2":-4.3193,"CHG":0.01165,"PCHG":0.40415,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-05 23:27:24","ADY":718,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-21","SUBJID":"id-21","SITEID":"JPN-1","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":13.29869,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-15","TRTSDTM":"2020-11-17 23:27:24","TRTEDTM":"2023-11-18 17:27:24","TRT01SDTM":"2020-11-17 23:27:24","TRT01EDTM":"2022-11-18 11:27:24","TRT02SDTM":"2022-11-18 11:27:24","TRT02EDTM":"2023-11-18 17:27:24","AP01SDTM":"2020-11-17 23:27:24","AP01EDTM":"2022-11-18 11:27:24","AP02SDTM":"2022-11-18 11:27:24","AP02EDTM":"2023-11-18 17:27:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-11-30","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2960,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81502,"AVALU":"g/L","BASE2":3.02443,"BASE":2.88215,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20941,"PCHG2":-6.9238,"CHG":-0.06712,"PCHG":-2.32892,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-26 23:27:24","ADY":1012,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-218","SUBJID":"id-218","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.8133,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-05","TRTSDTM":"2019-10-09 16:25:26","TRTEDTM":"2022-02-17 23:03:29","TRT01SDTM":"2019-10-09 16:25:26","TRT01EDTM":"2021-02-17 17:03:29","TRT02SDTM":"2021-02-17 17:03:29","TRT02EDTM":"2022-02-17 23:03:29","AP01SDTM":"2019-10-09 16:25:26","AP01EDTM":"2021-02-17 17:03:29","AP02SDTM":"2021-02-17 17:03:29","AP02EDTM":"2022-02-17 23:03:29","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5817,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.07192,"AVALU":"U/L","BASE2":14.07192,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-20 16:25:26","ADY":72,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-218","SUBJID":"id-218","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.8133,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-05","TRTSDTM":"2019-10-09 16:25:26","TRTEDTM":"2022-02-17 23:03:29","TRT01SDTM":"2019-10-09 16:25:26","TRT01EDTM":"2021-02-17 17:03:29","TRT02SDTM":"2021-02-17 17:03:29","TRT02EDTM":"2022-02-17 23:03:29","AP01SDTM":"2019-10-09 16:25:26","AP01EDTM":"2021-02-17 17:03:29","AP02SDTM":"2021-02-17 17:03:29","AP02EDTM":"2022-02-17 23:03:29","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5387,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.02423,"AVALU":"U/L","BASE2":14.07192,"BASE":15.02423,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.95231,"PCHG2":6.76742,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-18 16:25:26","ADY":192,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-218","SUBJID":"id-218","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.8133,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-05","TRTSDTM":"2019-10-09 16:25:26","TRTEDTM":"2022-02-17 23:03:29","TRT01SDTM":"2019-10-09 16:25:26","TRT01EDTM":"2021-02-17 17:03:29","TRT02SDTM":"2021-02-17 17:03:29","TRT02EDTM":"2022-02-17 23:03:29","AP01SDTM":"2019-10-09 16:25:26","AP01EDTM":"2021-02-17 17:03:29","AP02SDTM":"2021-02-17 17:03:29","AP02EDTM":"2022-02-17 23:03:29","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":550,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.53509,"AVALU":"U/L","BASE2":14.07192,"BASE":15.02423,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.46317,"PCHG2":95.67403,"CHG":12.51087,"PCHG":83.27129,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-08 16:25:26","ADY":457,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-218","SUBJID":"id-218","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.8133,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-05","TRTSDTM":"2019-10-09 16:25:26","TRTEDTM":"2022-02-17 23:03:29","TRT01SDTM":"2019-10-09 16:25:26","TRT01EDTM":"2021-02-17 17:03:29","TRT02SDTM":"2021-02-17 17:03:29","TRT02EDTM":"2022-02-17 23:03:29","AP01SDTM":"2019-10-09 16:25:26","AP01EDTM":"2021-02-17 17:03:29","AP02SDTM":"2021-02-17 17:03:29","AP02EDTM":"2022-02-17 23:03:29","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":326,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.65117,"AVALU":"U/L","BASE2":14.07192,"BASE":15.02423,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.57925,"PCHG2":110.71162,"CHG":14.62695,"PCHG":97.35573,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-10 16:25:26","ADY":549,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-218","SUBJID":"id-218","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.8133,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-05","TRTSDTM":"2019-10-09 16:25:26","TRTEDTM":"2022-02-17 23:03:29","TRT01SDTM":"2019-10-09 16:25:26","TRT01EDTM":"2021-02-17 17:03:29","TRT02SDTM":"2021-02-17 17:03:29","TRT02EDTM":"2022-02-17 23:03:29","AP01SDTM":"2019-10-09 16:25:26","AP01EDTM":"2021-02-17 17:03:29","AP02SDTM":"2021-02-17 17:03:29","AP02EDTM":"2022-02-17 23:03:29","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5759,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.7551,"AVALU":"U/L","BASE2":14.07192,"BASE":15.02423,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.68318,"PCHG2":118.55655,"CHG":15.73088,"PCHG":104.70341,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-28 16:25:26","ADY":567,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-218","SUBJID":"id-218","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.8133,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-05","TRTSDTM":"2019-10-09 16:25:26","TRTEDTM":"2022-02-17 23:03:29","TRT01SDTM":"2019-10-09 16:25:26","TRT01EDTM":"2021-02-17 17:03:29","TRT02SDTM":"2021-02-17 17:03:29","TRT02EDTM":"2022-02-17 23:03:29","AP01SDTM":"2019-10-09 16:25:26","AP01EDTM":"2021-02-17 17:03:29","AP02SDTM":"2021-02-17 17:03:29","AP02EDTM":"2022-02-17 23:03:29","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":809,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.16773,"AVALU":"U/L","BASE2":14.07192,"BASE":15.02423,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.90419,"PCHG2":-20.63821,"CHG":-3.8565,"PCHG":-25.66853,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-14 16:25:26","ADY":614,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-218","SUBJID":"id-218","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.8133,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-05","TRTSDTM":"2019-10-09 16:25:26","TRTEDTM":"2022-02-17 23:03:29","TRT01SDTM":"2019-10-09 16:25:26","TRT01EDTM":"2021-02-17 17:03:29","TRT02SDTM":"2021-02-17 17:03:29","TRT02EDTM":"2022-02-17 23:03:29","AP01SDTM":"2019-10-09 16:25:26","AP01EDTM":"2021-02-17 17:03:29","AP02SDTM":"2021-02-17 17:03:29","AP02EDTM":"2022-02-17 23:03:29","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4738,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.31746,"AVALU":"U/L","BASE2":14.07192,"BASE":15.02423,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.75446,"PCHG2":-83.53131,"CHG":-12.70677,"PCHG":-84.57517,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-08-20 16:25:26","ADY":681,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-218","SUBJID":"id-218","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.8133,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-05","TRTSDTM":"2019-10-09 16:25:26","TRTEDTM":"2022-02-17 23:03:29","TRT01SDTM":"2019-10-09 16:25:26","TRT01EDTM":"2021-02-17 17:03:29","TRT02SDTM":"2021-02-17 17:03:29","TRT02EDTM":"2022-02-17 23:03:29","AP01SDTM":"2019-10-09 16:25:26","AP01EDTM":"2021-02-17 17:03:29","AP02SDTM":"2021-02-17 17:03:29","AP02EDTM":"2022-02-17 23:03:29","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2492,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.09003,"AVALU":"mg/L","BASE2":10.09003,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"2","BTOXGR":"0","ADTM":"2019-12-20 16:25:26","ADY":72,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-218","SUBJID":"id-218","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.8133,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-05","TRTSDTM":"2019-10-09 16:25:26","TRTEDTM":"2022-02-17 23:03:29","TRT01SDTM":"2019-10-09 16:25:26","TRT01EDTM":"2021-02-17 17:03:29","TRT02SDTM":"2021-02-17 17:03:29","TRT02EDTM":"2022-02-17 23:03:29","AP01SDTM":"2019-10-09 16:25:26","AP01EDTM":"2021-02-17 17:03:29","AP02SDTM":"2021-02-17 17:03:29","AP02EDTM":"2022-02-17 23:03:29","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2749,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.26054,"AVALU":"mg/L","BASE2":10.09003,"BASE":8.26054,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.82948,"PCHG2":-18.13161,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-18 16:25:26","ADY":192,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-218","SUBJID":"id-218","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.8133,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-05","TRTSDTM":"2019-10-09 16:25:26","TRTEDTM":"2022-02-17 23:03:29","TRT01SDTM":"2019-10-09 16:25:26","TRT01EDTM":"2021-02-17 17:03:29","TRT02SDTM":"2021-02-17 17:03:29","TRT02EDTM":"2022-02-17 23:03:29","AP01SDTM":"2019-10-09 16:25:26","AP01EDTM":"2021-02-17 17:03:29","AP02SDTM":"2021-02-17 17:03:29","AP02EDTM":"2022-02-17 23:03:29","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4689,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.72185,"AVALU":"mg/L","BASE2":10.09003,"BASE":8.26054,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.36818,"PCHG2":-3.64891,"CHG":1.46131,"PCHG":17.69023,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-08 16:25:26","ADY":457,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-218","SUBJID":"id-218","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.8133,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-05","TRTSDTM":"2019-10-09 16:25:26","TRTEDTM":"2022-02-17 23:03:29","TRT01SDTM":"2019-10-09 16:25:26","TRT01EDTM":"2021-02-17 17:03:29","TRT02SDTM":"2021-02-17 17:03:29","TRT02EDTM":"2022-02-17 23:03:29","AP01SDTM":"2019-10-09 16:25:26","AP01EDTM":"2021-02-17 17:03:29","AP02SDTM":"2021-02-17 17:03:29","AP02EDTM":"2022-02-17 23:03:29","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5588,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.86442,"AVALU":"mg/L","BASE2":10.09003,"BASE":8.26054,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.22561,"PCHG2":-22.05753,"CHG":-0.39613,"PCHG":-4.79541,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-04-10 16:25:26","ADY":549,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-218","SUBJID":"id-218","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.8133,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-05","TRTSDTM":"2019-10-09 16:25:26","TRTEDTM":"2022-02-17 23:03:29","TRT01SDTM":"2019-10-09 16:25:26","TRT01EDTM":"2021-02-17 17:03:29","TRT02SDTM":"2021-02-17 17:03:29","TRT02EDTM":"2022-02-17 23:03:29","AP01SDTM":"2019-10-09 16:25:26","AP01EDTM":"2021-02-17 17:03:29","AP02SDTM":"2021-02-17 17:03:29","AP02EDTM":"2022-02-17 23:03:29","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":598,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.9049,"AVALU":"mg/L","BASE2":10.09003,"BASE":8.26054,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.18513,"PCHG2":-11.74551,"CHG":0.64436,"PCHG":7.80044,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-28 16:25:26","ADY":567,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-218","SUBJID":"id-218","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.8133,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-05","TRTSDTM":"2019-10-09 16:25:26","TRTEDTM":"2022-02-17 23:03:29","TRT01SDTM":"2019-10-09 16:25:26","TRT01EDTM":"2021-02-17 17:03:29","TRT02SDTM":"2021-02-17 17:03:29","TRT02EDTM":"2022-02-17 23:03:29","AP01SDTM":"2019-10-09 16:25:26","AP01EDTM":"2021-02-17 17:03:29","AP02SDTM":"2021-02-17 17:03:29","AP02EDTM":"2022-02-17 23:03:29","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3035,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.71611,"AVALU":"mg/L","BASE2":10.09003,"BASE":8.26054,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.37392,"PCHG2":-3.70581,"CHG":1.45557,"PCHG":17.62073,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-14 16:25:26","ADY":614,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-218","SUBJID":"id-218","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.8133,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-05","TRTSDTM":"2019-10-09 16:25:26","TRTEDTM":"2022-02-17 23:03:29","TRT01SDTM":"2019-10-09 16:25:26","TRT01EDTM":"2021-02-17 17:03:29","TRT02SDTM":"2021-02-17 17:03:29","TRT02EDTM":"2022-02-17 23:03:29","AP01SDTM":"2019-10-09 16:25:26","AP01EDTM":"2021-02-17 17:03:29","AP02SDTM":"2021-02-17 17:03:29","AP02EDTM":"2022-02-17 23:03:29","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5544,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.40813,"AVALU":"mg/L","BASE2":10.09003,"BASE":8.26054,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.6819,"PCHG2":-16.6689,"CHG":0.14759,"PCHG":1.78666,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-20 16:25:26","ADY":681,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-218","SUBJID":"id-218","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.8133,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-05","TRTSDTM":"2019-10-09 16:25:26","TRTEDTM":"2022-02-17 23:03:29","TRT01SDTM":"2019-10-09 16:25:26","TRT01EDTM":"2021-02-17 17:03:29","TRT02SDTM":"2021-02-17 17:03:29","TRT02EDTM":"2022-02-17 23:03:29","AP01SDTM":"2019-10-09 16:25:26","AP01EDTM":"2021-02-17 17:03:29","AP02SDTM":"2021-02-17 17:03:29","AP02EDTM":"2022-02-17 23:03:29","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6237,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95584,"AVALU":"g/L","BASE2":2.95584,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-20 16:25:26","ADY":72,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-218","SUBJID":"id-218","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.8133,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-05","TRTSDTM":"2019-10-09 16:25:26","TRTEDTM":"2022-02-17 23:03:29","TRT01SDTM":"2019-10-09 16:25:26","TRT01EDTM":"2021-02-17 17:03:29","TRT02SDTM":"2021-02-17 17:03:29","TRT02EDTM":"2022-02-17 23:03:29","AP01SDTM":"2019-10-09 16:25:26","AP01EDTM":"2021-02-17 17:03:29","AP02SDTM":"2021-02-17 17:03:29","AP02EDTM":"2022-02-17 23:03:29","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2217,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81266,"AVALU":"g/L","BASE2":2.95584,"BASE":2.81266,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.14318,"PCHG2":-4.84391,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-18 16:25:26","ADY":192,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-218","SUBJID":"id-218","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.8133,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-05","TRTSDTM":"2019-10-09 16:25:26","TRTEDTM":"2022-02-17 23:03:29","TRT01SDTM":"2019-10-09 16:25:26","TRT01EDTM":"2021-02-17 17:03:29","TRT02SDTM":"2021-02-17 17:03:29","TRT02EDTM":"2022-02-17 23:03:29","AP01SDTM":"2019-10-09 16:25:26","AP01EDTM":"2021-02-17 17:03:29","AP02SDTM":"2021-02-17 17:03:29","AP02EDTM":"2022-02-17 23:03:29","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":614,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96628,"AVALU":"g/L","BASE2":2.95584,"BASE":2.81266,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01044,"PCHG2":0.35318,"CHG":0.15362,"PCHG":5.46164,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-08 16:25:26","ADY":457,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-218","SUBJID":"id-218","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.8133,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-05","TRTSDTM":"2019-10-09 16:25:26","TRTEDTM":"2022-02-17 23:03:29","TRT01SDTM":"2019-10-09 16:25:26","TRT01EDTM":"2021-02-17 17:03:29","TRT02SDTM":"2021-02-17 17:03:29","TRT02EDTM":"2022-02-17 23:03:29","AP01SDTM":"2019-10-09 16:25:26","AP01EDTM":"2021-02-17 17:03:29","AP02SDTM":"2021-02-17 17:03:29","AP02EDTM":"2022-02-17 23:03:29","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4618,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88569,"AVALU":"g/L","BASE2":2.95584,"BASE":2.81266,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07015,"PCHG2":-2.37331,"CHG":0.07303,"PCHG":2.59636,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-10 16:25:26","ADY":549,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-218","SUBJID":"id-218","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.8133,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-05","TRTSDTM":"2019-10-09 16:25:26","TRTEDTM":"2022-02-17 23:03:29","TRT01SDTM":"2019-10-09 16:25:26","TRT01EDTM":"2021-02-17 17:03:29","TRT02SDTM":"2021-02-17 17:03:29","TRT02EDTM":"2022-02-17 23:03:29","AP01SDTM":"2019-10-09 16:25:26","AP01EDTM":"2021-02-17 17:03:29","AP02SDTM":"2021-02-17 17:03:29","AP02EDTM":"2022-02-17 23:03:29","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5249,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7538,"AVALU":"g/L","BASE2":2.95584,"BASE":2.81266,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20204,"PCHG2":-6.83515,"CHG":-0.05886,"PCHG":-2.09261,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-28 16:25:26","ADY":567,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-218","SUBJID":"id-218","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.8133,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-05","TRTSDTM":"2019-10-09 16:25:26","TRTEDTM":"2022-02-17 23:03:29","TRT01SDTM":"2019-10-09 16:25:26","TRT01EDTM":"2021-02-17 17:03:29","TRT02SDTM":"2021-02-17 17:03:29","TRT02EDTM":"2022-02-17 23:03:29","AP01SDTM":"2019-10-09 16:25:26","AP01EDTM":"2021-02-17 17:03:29","AP02SDTM":"2021-02-17 17:03:29","AP02EDTM":"2022-02-17 23:03:29","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4759,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93262,"AVALU":"g/L","BASE2":2.95584,"BASE":2.81266,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02322,"PCHG2":-0.78547,"CHG":0.11996,"PCHG":4.26503,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-14 16:25:26","ADY":614,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-218","SUBJID":"id-218","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.8133,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-05","TRTSDTM":"2019-10-09 16:25:26","TRTEDTM":"2022-02-17 23:03:29","TRT01SDTM":"2019-10-09 16:25:26","TRT01EDTM":"2021-02-17 17:03:29","TRT02SDTM":"2021-02-17 17:03:29","TRT02EDTM":"2022-02-17 23:03:29","AP01SDTM":"2019-10-09 16:25:26","AP01EDTM":"2021-02-17 17:03:29","AP02SDTM":"2021-02-17 17:03:29","AP02EDTM":"2022-02-17 23:03:29","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":863,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7357,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84321,"AVALU":"g/L","BASE2":2.95584,"BASE":2.81266,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11263,"PCHG2":-3.81052,"CHG":0.03055,"PCHG":1.08599,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-20 16:25:26","ADY":681,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-225","SUBJID":"id-225","SITEID":"JPN-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.86373,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-07 03:36:02","TRT01SDTM":"2019-12-07 03:36:02","AP01SDTM":"2019-12-07 03:36:02","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4630,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.50187,"AVALU":"U/L","BASE2":22.50187,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-05-13 03:36:02","ADY":158,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-225","SUBJID":"id-225","SITEID":"JPN-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.86373,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-07 03:36:02","TRT01SDTM":"2019-12-07 03:36:02","AP01SDTM":"2019-12-07 03:36:02","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":206,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.95688,"AVALU":"U/L","BASE2":22.50187,"BASE":1.95688,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-20.54499,"PCHG2":-91.30349,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2020-08-26 03:36:02","ADY":263,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-225","SUBJID":"id-225","SITEID":"JPN-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.86373,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-07 03:36:02","TRT01SDTM":"2019-12-07 03:36:02","AP01SDTM":"2019-12-07 03:36:02","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7187,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.57415,"AVALU":"U/L","BASE2":22.50187,"BASE":1.95688,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.07227,"PCHG2":9.20934,"CHG":22.61727,"PCHG":1155.78316,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-03-16 03:36:02","ADY":465,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-225","SUBJID":"id-225","SITEID":"JPN-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.86373,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-07 03:36:02","TRT01SDTM":"2019-12-07 03:36:02","AP01SDTM":"2019-12-07 03:36:02","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6198,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.71243,"AVALU":"U/L","BASE2":22.50187,"BASE":1.95688,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.78944,"PCHG2":-43.50501,"CHG":10.75555,"PCHG":549.62813,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-05-02 03:36:02","ADY":512,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-225","SUBJID":"id-225","SITEID":"JPN-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.86373,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-07 03:36:02","TRT01SDTM":"2019-12-07 03:36:02","AP01SDTM":"2019-12-07 03:36:02","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1935,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.87187,"AVALU":"U/L","BASE2":22.50187,"BASE":1.95688,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-19.63,"PCHG2":-87.23717,"CHG":0.915,"PCHG":46.75799,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-2","ADTM":"2021-09-29 03:36:02","ADY":662,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-225","SUBJID":"id-225","SITEID":"JPN-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.86373,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-07 03:36:02","TRT01SDTM":"2019-12-07 03:36:02","AP01SDTM":"2019-12-07 03:36:02","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4419,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.90752,"AVALU":"U/L","BASE2":22.50187,"BASE":1.95688,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.59435,"PCHG2":-73.74655,"CHG":3.95064,"PCHG":201.88477,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2021-10-31 03:36:02","ADY":694,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-225","SUBJID":"id-225","SITEID":"JPN-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.86373,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-07 03:36:02","TRT01SDTM":"2019-12-07 03:36:02","AP01SDTM":"2019-12-07 03:36:02","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4715,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.58562,"AVALU":"U/L","BASE2":22.50187,"BASE":1.95688,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.91625,"PCHG2":-35.18041,"CHG":12.62874,"PCHG":645.35153,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-12-02 03:36:02","ADY":726,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-225","SUBJID":"id-225","SITEID":"JPN-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.86373,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-07 03:36:02","TRT01SDTM":"2019-12-07 03:36:02","AP01SDTM":"2019-12-07 03:36:02","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5760,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.67609,"AVALU":"mg/L","BASE2":10.67609,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"","ATOXGR":"3","BTOXGR":"-1","ADTM":"2020-05-13 03:36:02","ADY":158,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-225","SUBJID":"id-225","SITEID":"JPN-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.86373,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-07 03:36:02","TRT01SDTM":"2019-12-07 03:36:02","AP01SDTM":"2019-12-07 03:36:02","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4111,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.10574,"AVALU":"mg/L","BASE2":10.67609,"BASE":7.10574,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-3.57036,"PCHG2":-33.44254,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2020-08-26 03:36:02","ADY":263,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-225","SUBJID":"id-225","SITEID":"JPN-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.86373,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-07 03:36:02","TRT01SDTM":"2019-12-07 03:36:02","AP01SDTM":"2019-12-07 03:36:02","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7664,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.17022,"AVALU":"mg/L","BASE2":10.67609,"BASE":7.10574,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.50588,"PCHG2":-14.10514,"CHG":2.06448,"PCHG":29.0537,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-03-16 03:36:02","ADY":465,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-225","SUBJID":"id-225","SITEID":"JPN-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.86373,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-07 03:36:02","TRT01SDTM":"2019-12-07 03:36:02","AP01SDTM":"2019-12-07 03:36:02","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1794,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.05093,"AVALU":"mg/L","BASE2":10.67609,"BASE":7.10574,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.62516,"PCHG2":-24.58915,"CHG":0.9452,"PCHG":13.30187,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-05-02 03:36:02","ADY":512,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-225","SUBJID":"id-225","SITEID":"JPN-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.86373,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-07 03:36:02","TRT01SDTM":"2019-12-07 03:36:02","AP01SDTM":"2019-12-07 03:36:02","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1249,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.63805,"AVALU":"mg/L","BASE2":10.67609,"BASE":7.10574,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.03805,"PCHG2":-19.08983,"CHG":1.53231,"PCHG":21.56439,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-09-29 03:36:02","ADY":662,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-225","SUBJID":"id-225","SITEID":"JPN-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.86373,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-07 03:36:02","TRT01SDTM":"2019-12-07 03:36:02","AP01SDTM":"2019-12-07 03:36:02","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4143,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.97064,"AVALU":"mg/L","BASE2":10.67609,"BASE":7.10574,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.70545,"PCHG2":-15.9745,"CHG":1.8649,"PCHG":26.24506,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-10-31 03:36:02","ADY":694,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-225","SUBJID":"id-225","SITEID":"JPN-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.86373,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-07 03:36:02","TRT01SDTM":"2019-12-07 03:36:02","AP01SDTM":"2019-12-07 03:36:02","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":502,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.19109,"AVALU":"mg/L","BASE2":10.67609,"BASE":7.10574,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.48501,"PCHG2":-4.54294,"CHG":3.08535,"PCHG":43.42054,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"2","BTOXGR":"-1","ADTM":"2021-12-02 03:36:02","ADY":726,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-225","SUBJID":"id-225","SITEID":"JPN-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.86373,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-07 03:36:02","TRT01SDTM":"2019-12-07 03:36:02","AP01SDTM":"2019-12-07 03:36:02","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":168,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96039,"AVALU":"g/L","BASE2":2.96039,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-13 03:36:02","ADY":158,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-225","SUBJID":"id-225","SITEID":"JPN-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.86373,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-07 03:36:02","TRT01SDTM":"2019-12-07 03:36:02","AP01SDTM":"2019-12-07 03:36:02","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5404,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89784,"AVALU":"g/L","BASE2":2.96039,"BASE":2.89784,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.06255,"PCHG2":-2.11274,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-26 03:36:02","ADY":263,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-225","SUBJID":"id-225","SITEID":"JPN-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.86373,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-07 03:36:02","TRT01SDTM":"2019-12-07 03:36:02","AP01SDTM":"2019-12-07 03:36:02","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5720,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74321,"AVALU":"g/L","BASE2":2.96039,"BASE":2.89784,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21718,"PCHG2":-7.33615,"CHG":-0.15463,"PCHG":-5.33614,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-16 03:36:02","ADY":465,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-225","SUBJID":"id-225","SITEID":"JPN-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.86373,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-07 03:36:02","TRT01SDTM":"2019-12-07 03:36:02","AP01SDTM":"2019-12-07 03:36:02","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3637,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88843,"AVALU":"g/L","BASE2":2.96039,"BASE":2.89784,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07196,"PCHG2":-2.43075,"CHG":-0.00941,"PCHG":-0.32488,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-02 03:36:02","ADY":512,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-225","SUBJID":"id-225","SITEID":"JPN-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.86373,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-07 03:36:02","TRT01SDTM":"2019-12-07 03:36:02","AP01SDTM":"2019-12-07 03:36:02","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1351,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00714,"AVALU":"g/L","BASE2":2.96039,"BASE":2.89784,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04675,"PCHG2":1.57924,"CHG":0.1093,"PCHG":3.77166,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-09-29 03:36:02","ADY":662,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-225","SUBJID":"id-225","SITEID":"JPN-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.86373,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-07 03:36:02","TRT01SDTM":"2019-12-07 03:36:02","AP01SDTM":"2019-12-07 03:36:02","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3269,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96675,"AVALU":"g/L","BASE2":2.96039,"BASE":2.89784,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00637,"PCHG2":0.21501,"CHG":0.06891,"PCHG":2.378,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-31 03:36:02","ADY":694,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-225","SUBJID":"id-225","SITEID":"JPN-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":1.86373,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-07 03:36:02","TRT01SDTM":"2019-12-07 03:36:02","AP01SDTM":"2019-12-07 03:36:02","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7234,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9237,"AVALU":"g/L","BASE2":2.96039,"BASE":2.89784,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03669,"PCHG2":-1.23922,"CHG":0.02586,"PCHG":0.89237,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-02 03:36:02","ADY":726,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-300","SUBJID":"id-300","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.97287,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-04","TRTSDTM":"2020-05-07 07:48:41","TRTEDTM":"2022-02-19 19:46:51","TRT01SDTM":"2020-05-07 07:48:41","TRT01EDTM":"2021-02-19 13:46:51","TRT02SDTM":"2021-02-19 13:46:51","TRT02EDTM":"2022-02-19 19:46:51","AP01SDTM":"2020-05-07 07:48:41","AP01EDTM":"2021-02-19 13:46:51","AP02SDTM":"2021-02-19 13:46:51","AP02EDTM":"2022-02-19 19:46:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":654,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-02","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3818,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.20464,"AVALU":"U/L","BASE2":28.20464,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-10 07:48:41","ADY":95,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-300","SUBJID":"id-300","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.97287,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-04","TRTSDTM":"2020-05-07 07:48:41","TRTEDTM":"2022-02-19 19:46:51","TRT01SDTM":"2020-05-07 07:48:41","TRT01EDTM":"2021-02-19 13:46:51","TRT02SDTM":"2021-02-19 13:46:51","TRT02EDTM":"2022-02-19 19:46:51","AP01SDTM":"2020-05-07 07:48:41","AP01EDTM":"2021-02-19 13:46:51","AP02SDTM":"2021-02-19 13:46:51","AP02EDTM":"2022-02-19 19:46:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":654,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-02","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2359,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.30964,"AVALU":"U/L","BASE2":28.20464,"BASE":15.30964,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-12.895,"PCHG2":-45.71942,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-18 07:48:41","ADY":103,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-300","SUBJID":"id-300","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.97287,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-04","TRTSDTM":"2020-05-07 07:48:41","TRTEDTM":"2022-02-19 19:46:51","TRT01SDTM":"2020-05-07 07:48:41","TRT01EDTM":"2021-02-19 13:46:51","TRT02SDTM":"2021-02-19 13:46:51","TRT02EDTM":"2022-02-19 19:46:51","AP01SDTM":"2020-05-07 07:48:41","AP01EDTM":"2021-02-19 13:46:51","AP02SDTM":"2021-02-19 13:46:51","AP02EDTM":"2022-02-19 19:46:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":654,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-02","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2596,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.74893,"AVALU":"U/L","BASE2":28.20464,"BASE":15.30964,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.54429,"PCHG2":5.4753,"CHG":14.43929,"PCHG":94.31501,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-19 07:48:41","ADY":135,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-300","SUBJID":"id-300","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.97287,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-04","TRTSDTM":"2020-05-07 07:48:41","TRTEDTM":"2022-02-19 19:46:51","TRT01SDTM":"2020-05-07 07:48:41","TRT01EDTM":"2021-02-19 13:46:51","TRT02SDTM":"2021-02-19 13:46:51","TRT02EDTM":"2022-02-19 19:46:51","AP01SDTM":"2020-05-07 07:48:41","AP01EDTM":"2021-02-19 13:46:51","AP02SDTM":"2021-02-19 13:46:51","AP02EDTM":"2022-02-19 19:46:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":654,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-02","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7507,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.36476,"AVALU":"U/L","BASE2":28.20464,"BASE":15.30964,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16012,"PCHG2":0.56771,"CHG":13.05512,"PCHG":85.27384,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-20 07:48:41","ADY":136,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-300","SUBJID":"id-300","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.97287,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-04","TRTSDTM":"2020-05-07 07:48:41","TRTEDTM":"2022-02-19 19:46:51","TRT01SDTM":"2020-05-07 07:48:41","TRT01EDTM":"2021-02-19 13:46:51","TRT02SDTM":"2021-02-19 13:46:51","TRT02EDTM":"2022-02-19 19:46:51","AP01SDTM":"2020-05-07 07:48:41","AP01EDTM":"2021-02-19 13:46:51","AP02SDTM":"2021-02-19 13:46:51","AP02EDTM":"2022-02-19 19:46:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":654,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-02","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8114,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.09166,"AVALU":"U/L","BASE2":28.20464,"BASE":15.30964,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.11298,"PCHG2":-57.12883,"CHG":-3.21798,"PCHG":-21.01932,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-11 07:48:41","ADY":369,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-300","SUBJID":"id-300","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.97287,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-04","TRTSDTM":"2020-05-07 07:48:41","TRTEDTM":"2022-02-19 19:46:51","TRT01SDTM":"2020-05-07 07:48:41","TRT01EDTM":"2021-02-19 13:46:51","TRT02SDTM":"2021-02-19 13:46:51","TRT02EDTM":"2022-02-19 19:46:51","AP01SDTM":"2020-05-07 07:48:41","AP01EDTM":"2021-02-19 13:46:51","AP02SDTM":"2021-02-19 13:46:51","AP02EDTM":"2022-02-19 19:46:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":654,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-02","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2009,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.84314,"AVALU":"U/L","BASE2":28.20464,"BASE":15.30964,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.3615,"PCHG2":-15.46375,"CHG":8.5335,"PCHG":55.7394,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-15 07:48:41","ADY":373,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-300","SUBJID":"id-300","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.97287,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-04","TRTSDTM":"2020-05-07 07:48:41","TRTEDTM":"2022-02-19 19:46:51","TRT01SDTM":"2020-05-07 07:48:41","TRT01EDTM":"2021-02-19 13:46:51","TRT02SDTM":"2021-02-19 13:46:51","TRT02EDTM":"2022-02-19 19:46:51","AP01SDTM":"2020-05-07 07:48:41","AP01EDTM":"2021-02-19 13:46:51","AP02SDTM":"2021-02-19 13:46:51","AP02EDTM":"2022-02-19 19:46:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":654,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-02","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7359,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.15007,"AVALU":"U/L","BASE2":28.20464,"BASE":15.30964,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.94543,"PCHG2":6.89755,"CHG":14.84043,"PCHG":96.93518,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-15 07:48:41","ADY":526,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-300","SUBJID":"id-300","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.97287,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-04","TRTSDTM":"2020-05-07 07:48:41","TRTEDTM":"2022-02-19 19:46:51","TRT01SDTM":"2020-05-07 07:48:41","TRT01EDTM":"2021-02-19 13:46:51","TRT02SDTM":"2021-02-19 13:46:51","TRT02EDTM":"2022-02-19 19:46:51","AP01SDTM":"2020-05-07 07:48:41","AP01EDTM":"2021-02-19 13:46:51","AP02SDTM":"2021-02-19 13:46:51","AP02EDTM":"2022-02-19 19:46:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":654,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-02","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5713,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.50359,"AVALU":"mg/L","BASE2":9.50359,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-10 07:48:41","ADY":95,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-300","SUBJID":"id-300","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.97287,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-04","TRTSDTM":"2020-05-07 07:48:41","TRTEDTM":"2022-02-19 19:46:51","TRT01SDTM":"2020-05-07 07:48:41","TRT01EDTM":"2021-02-19 13:46:51","TRT02SDTM":"2021-02-19 13:46:51","TRT02EDTM":"2022-02-19 19:46:51","AP01SDTM":"2020-05-07 07:48:41","AP01EDTM":"2021-02-19 13:46:51","AP02SDTM":"2021-02-19 13:46:51","AP02EDTM":"2022-02-19 19:46:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":654,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-02","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1235,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.45486,"AVALU":"mg/L","BASE2":9.50359,"BASE":8.45486,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.04872,"PCHG2":-11.03504,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-18 07:48:41","ADY":103,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-300","SUBJID":"id-300","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.97287,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-04","TRTSDTM":"2020-05-07 07:48:41","TRTEDTM":"2022-02-19 19:46:51","TRT01SDTM":"2020-05-07 07:48:41","TRT01EDTM":"2021-02-19 13:46:51","TRT02SDTM":"2021-02-19 13:46:51","TRT02EDTM":"2022-02-19 19:46:51","AP01SDTM":"2020-05-07 07:48:41","AP01EDTM":"2021-02-19 13:46:51","AP02SDTM":"2021-02-19 13:46:51","AP02EDTM":"2022-02-19 19:46:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":654,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-02","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5844,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.75236,"AVALU":"mg/L","BASE2":9.50359,"BASE":8.45486,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.24877,"PCHG2":13.13996,"CHG":2.29749,"PCHG":27.17362,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-09-19 07:48:41","ADY":135,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-300","SUBJID":"id-300","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.97287,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-04","TRTSDTM":"2020-05-07 07:48:41","TRTEDTM":"2022-02-19 19:46:51","TRT01SDTM":"2020-05-07 07:48:41","TRT01EDTM":"2021-02-19 13:46:51","TRT02SDTM":"2021-02-19 13:46:51","TRT02EDTM":"2022-02-19 19:46:51","AP01SDTM":"2020-05-07 07:48:41","AP01EDTM":"2021-02-19 13:46:51","AP02SDTM":"2021-02-19 13:46:51","AP02EDTM":"2022-02-19 19:46:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":654,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-02","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3217,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.74662,"AVALU":"mg/L","BASE2":9.50359,"BASE":8.45486,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.75697,"PCHG2":-7.96505,"CHG":0.29176,"PCHG":3.45079,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-20 07:48:41","ADY":136,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-300","SUBJID":"id-300","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.97287,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-04","TRTSDTM":"2020-05-07 07:48:41","TRTEDTM":"2022-02-19 19:46:51","TRT01SDTM":"2020-05-07 07:48:41","TRT01EDTM":"2021-02-19 13:46:51","TRT02SDTM":"2021-02-19 13:46:51","TRT02EDTM":"2022-02-19 19:46:51","AP01SDTM":"2020-05-07 07:48:41","AP01EDTM":"2021-02-19 13:46:51","AP02SDTM":"2021-02-19 13:46:51","AP02EDTM":"2022-02-19 19:46:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":654,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-02","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":800,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.40165,"AVALU":"mg/L","BASE2":9.50359,"BASE":8.45486,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.10194,"PCHG2":-11.59502,"CHG":-0.05322,"PCHG":-0.62944,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-11 07:48:41","ADY":369,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-300","SUBJID":"id-300","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.97287,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-04","TRTSDTM":"2020-05-07 07:48:41","TRTEDTM":"2022-02-19 19:46:51","TRT01SDTM":"2020-05-07 07:48:41","TRT01EDTM":"2021-02-19 13:46:51","TRT02SDTM":"2021-02-19 13:46:51","TRT02EDTM":"2022-02-19 19:46:51","AP01SDTM":"2020-05-07 07:48:41","AP01EDTM":"2021-02-19 13:46:51","AP02SDTM":"2021-02-19 13:46:51","AP02EDTM":"2022-02-19 19:46:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":654,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-02","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4769,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.29948,"AVALU":"mg/L","BASE2":9.50359,"BASE":8.45486,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.20411,"PCHG2":-12.67003,"CHG":-0.15538,"PCHG":-1.83779,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-15 07:48:41","ADY":373,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-300","SUBJID":"id-300","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.97287,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-04","TRTSDTM":"2020-05-07 07:48:41","TRTEDTM":"2022-02-19 19:46:51","TRT01SDTM":"2020-05-07 07:48:41","TRT01EDTM":"2021-02-19 13:46:51","TRT02SDTM":"2021-02-19 13:46:51","TRT02EDTM":"2022-02-19 19:46:51","AP01SDTM":"2020-05-07 07:48:41","AP01EDTM":"2021-02-19 13:46:51","AP02SDTM":"2021-02-19 13:46:51","AP02EDTM":"2022-02-19 19:46:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":654,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-02","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3357,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.1903,"AVALU":"mg/L","BASE2":9.50359,"BASE":8.45486,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.31329,"PCHG2":-24.34122,"CHG":-1.26457,"PCHG":-14.95666,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-10-15 07:48:41","ADY":526,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-300","SUBJID":"id-300","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.97287,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-04","TRTSDTM":"2020-05-07 07:48:41","TRTEDTM":"2022-02-19 19:46:51","TRT01SDTM":"2020-05-07 07:48:41","TRT01EDTM":"2021-02-19 13:46:51","TRT02SDTM":"2021-02-19 13:46:51","TRT02EDTM":"2022-02-19 19:46:51","AP01SDTM":"2020-05-07 07:48:41","AP01EDTM":"2021-02-19 13:46:51","AP02SDTM":"2021-02-19 13:46:51","AP02EDTM":"2022-02-19 19:46:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":654,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-02","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":183,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8597,"AVALU":"g/L","BASE2":2.8597,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-10 07:48:41","ADY":95,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-300","SUBJID":"id-300","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.97287,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-04","TRTSDTM":"2020-05-07 07:48:41","TRTEDTM":"2022-02-19 19:46:51","TRT01SDTM":"2020-05-07 07:48:41","TRT01EDTM":"2021-02-19 13:46:51","TRT02SDTM":"2021-02-19 13:46:51","TRT02EDTM":"2022-02-19 19:46:51","AP01SDTM":"2020-05-07 07:48:41","AP01EDTM":"2021-02-19 13:46:51","AP02SDTM":"2021-02-19 13:46:51","AP02EDTM":"2022-02-19 19:46:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":654,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-02","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":443,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77983,"AVALU":"g/L","BASE2":2.8597,"BASE":2.77983,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.07987,"PCHG2":-2.79302,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-18 07:48:41","ADY":103,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-300","SUBJID":"id-300","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.97287,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-04","TRTSDTM":"2020-05-07 07:48:41","TRTEDTM":"2022-02-19 19:46:51","TRT01SDTM":"2020-05-07 07:48:41","TRT01EDTM":"2021-02-19 13:46:51","TRT02SDTM":"2021-02-19 13:46:51","TRT02EDTM":"2022-02-19 19:46:51","AP01SDTM":"2020-05-07 07:48:41","AP01EDTM":"2021-02-19 13:46:51","AP02SDTM":"2021-02-19 13:46:51","AP02EDTM":"2022-02-19 19:46:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":654,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-02","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6505,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96712,"AVALU":"g/L","BASE2":2.8597,"BASE":2.77983,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10742,"PCHG2":3.75622,"CHG":0.18729,"PCHG":6.73741,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-19 07:48:41","ADY":135,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-300","SUBJID":"id-300","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.97287,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-04","TRTSDTM":"2020-05-07 07:48:41","TRTEDTM":"2022-02-19 19:46:51","TRT01SDTM":"2020-05-07 07:48:41","TRT01EDTM":"2021-02-19 13:46:51","TRT02SDTM":"2021-02-19 13:46:51","TRT02EDTM":"2022-02-19 19:46:51","AP01SDTM":"2020-05-07 07:48:41","AP01EDTM":"2021-02-19 13:46:51","AP02SDTM":"2021-02-19 13:46:51","AP02EDTM":"2022-02-19 19:46:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":654,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-02","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8293,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84212,"AVALU":"g/L","BASE2":2.8597,"BASE":2.77983,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01758,"PCHG2":-0.61472,"CHG":0.06229,"PCHG":2.24088,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-20 07:48:41","ADY":136,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-300","SUBJID":"id-300","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.97287,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-04","TRTSDTM":"2020-05-07 07:48:41","TRTEDTM":"2022-02-19 19:46:51","TRT01SDTM":"2020-05-07 07:48:41","TRT01EDTM":"2021-02-19 13:46:51","TRT02SDTM":"2021-02-19 13:46:51","TRT02EDTM":"2022-02-19 19:46:51","AP01SDTM":"2020-05-07 07:48:41","AP01EDTM":"2021-02-19 13:46:51","AP02SDTM":"2021-02-19 13:46:51","AP02EDTM":"2022-02-19 19:46:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":654,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-02","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3577,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7947,"AVALU":"g/L","BASE2":2.8597,"BASE":2.77983,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.065,"PCHG2":-2.27303,"CHG":0.01487,"PCHG":0.53493,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-11 07:48:41","ADY":369,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-300","SUBJID":"id-300","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.97287,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-04","TRTSDTM":"2020-05-07 07:48:41","TRTEDTM":"2022-02-19 19:46:51","TRT01SDTM":"2020-05-07 07:48:41","TRT01EDTM":"2021-02-19 13:46:51","TRT02SDTM":"2021-02-19 13:46:51","TRT02EDTM":"2022-02-19 19:46:51","AP01SDTM":"2020-05-07 07:48:41","AP01EDTM":"2021-02-19 13:46:51","AP02SDTM":"2021-02-19 13:46:51","AP02EDTM":"2022-02-19 19:46:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":654,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-02","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6382,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96702,"AVALU":"g/L","BASE2":2.8597,"BASE":2.77983,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10732,"PCHG2":3.75281,"CHG":0.18719,"PCHG":6.73391,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-15 07:48:41","ADY":373,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-300","SUBJID":"id-300","SITEID":"JPN-1","AGE":35,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":6.97287,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-04","TRTSDTM":"2020-05-07 07:48:41","TRTEDTM":"2022-02-19 19:46:51","TRT01SDTM":"2020-05-07 07:48:41","TRT01EDTM":"2021-02-19 13:46:51","TRT02SDTM":"2021-02-19 13:46:51","TRT02EDTM":"2022-02-19 19:46:51","AP01SDTM":"2020-05-07 07:48:41","AP01EDTM":"2021-02-19 13:46:51","AP02SDTM":"2021-02-19 13:46:51","AP02EDTM":"2022-02-19 19:46:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":654,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-02","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5251,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78113,"AVALU":"g/L","BASE2":2.8597,"BASE":2.77983,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07857,"PCHG2":-2.74738,"CHG":0.00131,"PCHG":0.04695,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-15 07:48:41","ADY":526,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-7","SUBJID":"id-7","SITEID":"JPN-1","AGE":54,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.08724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-10 08:49:00","TRT01SDTM":"2019-10-10 08:49:00","AP01SDTM":"2019-10-10 08:49:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2014,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.80007,"AVALU":"U/L","BASE2":14.80007,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-27 08:49:00","ADY":17,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-7","SUBJID":"id-7","SITEID":"JPN-1","AGE":54,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.08724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-10 08:49:00","TRT01SDTM":"2019-10-10 08:49:00","AP01SDTM":"2019-10-10 08:49:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7483,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.32321,"AVALU":"U/L","BASE2":14.80007,"BASE":16.32321,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.52314,"PCHG2":10.29142,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-16 08:49:00","ADY":129,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-7","SUBJID":"id-7","SITEID":"JPN-1","AGE":54,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.08724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-10 08:49:00","TRT01SDTM":"2019-10-10 08:49:00","AP01SDTM":"2019-10-10 08:49:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4836,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.91299,"AVALU":"U/L","BASE2":14.80007,"BASE":16.32321,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.88708,"PCHG2":-93.8312,"CHG":-15.41022,"PCHG":-94.40682,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-03-24 08:49:00","ADY":166,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-7","SUBJID":"id-7","SITEID":"JPN-1","AGE":54,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.08724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-10 08:49:00","TRT01SDTM":"2019-10-10 08:49:00","AP01SDTM":"2019-10-10 08:49:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1183,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.77415,"AVALU":"U/L","BASE2":14.80007,"BASE":16.32321,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.97408,"PCHG2":6.58159,"CHG":-0.54906,"PCHG":-3.36366,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-30 08:49:00","ADY":264,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-7","SUBJID":"id-7","SITEID":"JPN-1","AGE":54,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.08724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-10 08:49:00","TRT01SDTM":"2019-10-10 08:49:00","AP01SDTM":"2019-10-10 08:49:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5508,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.7582,"AVALU":"U/L","BASE2":14.80007,"BASE":16.32321,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.04188,"PCHG2":-88.12036,"CHG":-14.56501,"PCHG":-89.22886,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-02-28 08:49:00","ADY":507,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-7","SUBJID":"id-7","SITEID":"JPN-1","AGE":54,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.08724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-10 08:49:00","TRT01SDTM":"2019-10-10 08:49:00","AP01SDTM":"2019-10-10 08:49:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5522,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.5798,"AVALU":"U/L","BASE2":14.80007,"BASE":16.32321,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.77973,"PCHG2":113.37603,"CHG":15.2566,"PCHG":93.46567,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-21 08:49:00","ADY":589,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-7","SUBJID":"id-7","SITEID":"JPN-1","AGE":54,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.08724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-10 08:49:00","TRT01SDTM":"2019-10-10 08:49:00","AP01SDTM":"2019-10-10 08:49:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1454,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.47875,"AVALU":"U/L","BASE2":14.80007,"BASE":16.32321,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.67868,"PCHG2":99.1798,"CHG":13.15554,"PCHG":80.59411,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-17 08:49:00","ADY":646,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-7","SUBJID":"id-7","SITEID":"JPN-1","AGE":54,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.08724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-10 08:49:00","TRT01SDTM":"2019-10-10 08:49:00","AP01SDTM":"2019-10-10 08:49:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5780,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.81112,"AVALU":"mg/L","BASE2":9.81112,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"2","ADTM":"2019-10-27 08:49:00","ADY":17,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-7","SUBJID":"id-7","SITEID":"JPN-1","AGE":54,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.08724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-10 08:49:00","TRT01SDTM":"2019-10-10 08:49:00","AP01SDTM":"2019-10-10 08:49:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2694,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.07937,"AVALU":"mg/L","BASE2":9.81112,"BASE":11.07937,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.26824,"PCHG2":12.92655,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2020-02-16 08:49:00","ADY":129,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-7","SUBJID":"id-7","SITEID":"JPN-1","AGE":54,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.08724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-10 08:49:00","TRT01SDTM":"2019-10-10 08:49:00","AP01SDTM":"2019-10-10 08:49:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3512,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.79829,"AVALU":"mg/L","BASE2":9.81112,"BASE":11.07937,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.01283,"PCHG2":-20.51582,"CHG":-3.28107,"PCHG":-29.61427,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-4","BTOXGR":"2","ADTM":"2020-03-24 08:49:00","ADY":166,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-7","SUBJID":"id-7","SITEID":"JPN-1","AGE":54,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.08724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-10 08:49:00","TRT01SDTM":"2019-10-10 08:49:00","AP01SDTM":"2019-10-10 08:49:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6270,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.90905,"AVALU":"mg/L","BASE2":9.81112,"BASE":11.07937,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09792,"PCHG2":0.99806,"CHG":-1.17032,"PCHG":-10.56306,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2020-06-30 08:49:00","ADY":264,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-7","SUBJID":"id-7","SITEID":"JPN-1","AGE":54,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.08724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-10 08:49:00","TRT01SDTM":"2019-10-10 08:49:00","AP01SDTM":"2019-10-10 08:49:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3422,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.49664,"AVALU":"mg/L","BASE2":9.81112,"BASE":11.07937,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.31448,"PCHG2":-13.39785,"CHG":-2.58272,"PCHG":-23.31109,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-02-28 08:49:00","ADY":507,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-7","SUBJID":"id-7","SITEID":"JPN-1","AGE":54,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.08724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-10 08:49:00","TRT01SDTM":"2019-10-10 08:49:00","AP01SDTM":"2019-10-10 08:49:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7714,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.54143,"AVALU":"mg/L","BASE2":9.81112,"BASE":11.07937,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.26969,"PCHG2":-2.74884,"CHG":-1.53793,"PCHG":-13.88105,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-05-21 08:49:00","ADY":589,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-7","SUBJID":"id-7","SITEID":"JPN-1","AGE":54,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.08724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-10 08:49:00","TRT01SDTM":"2019-10-10 08:49:00","AP01SDTM":"2019-10-10 08:49:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4430,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.293,"AVALU":"mg/L","BASE2":9.81112,"BASE":11.07937,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.51813,"PCHG2":-5.28104,"CHG":-1.78637,"PCHG":-16.1234,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-07-17 08:49:00","ADY":646,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-7","SUBJID":"id-7","SITEID":"JPN-1","AGE":54,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.08724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-10 08:49:00","TRT01SDTM":"2019-10-10 08:49:00","AP01SDTM":"2019-10-10 08:49:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6852,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76609,"AVALU":"g/L","BASE2":2.76609,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-27 08:49:00","ADY":17,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-7","SUBJID":"id-7","SITEID":"JPN-1","AGE":54,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.08724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-10 08:49:00","TRT01SDTM":"2019-10-10 08:49:00","AP01SDTM":"2019-10-10 08:49:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7116,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99355,"AVALU":"g/L","BASE2":2.76609,"BASE":2.99355,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.22746,"PCHG2":8.22318,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-16 08:49:00","ADY":129,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-7","SUBJID":"id-7","SITEID":"JPN-1","AGE":54,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.08724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-10 08:49:00","TRT01SDTM":"2019-10-10 08:49:00","AP01SDTM":"2019-10-10 08:49:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":547,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92674,"AVALU":"g/L","BASE2":2.76609,"BASE":2.99355,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16065,"PCHG2":5.80793,"CHG":-0.06681,"PCHG":-2.23173,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-24 08:49:00","ADY":166,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-7","SUBJID":"id-7","SITEID":"JPN-1","AGE":54,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.08724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-10 08:49:00","TRT01SDTM":"2019-10-10 08:49:00","AP01SDTM":"2019-10-10 08:49:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1882,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81065,"AVALU":"g/L","BASE2":2.76609,"BASE":2.99355,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04456,"PCHG2":1.61103,"CHG":-0.1829,"PCHG":-6.10973,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-30 08:49:00","ADY":264,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-7","SUBJID":"id-7","SITEID":"JPN-1","AGE":54,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.08724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-10 08:49:00","TRT01SDTM":"2019-10-10 08:49:00","AP01SDTM":"2019-10-10 08:49:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6613,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91893,"AVALU":"g/L","BASE2":2.76609,"BASE":2.99355,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15284,"PCHG2":5.52536,"CHG":-0.07462,"PCHG":-2.49282,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-28 08:49:00","ADY":507,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-7","SUBJID":"id-7","SITEID":"JPN-1","AGE":54,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.08724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-10 08:49:00","TRT01SDTM":"2019-10-10 08:49:00","AP01SDTM":"2019-10-10 08:49:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2438,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78309,"AVALU":"g/L","BASE2":2.76609,"BASE":2.99355,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.017,"PCHG2":0.61466,"CHG":-0.21046,"PCHG":-7.03039,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-21 08:49:00","ADY":589,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-1-id-7","SUBJID":"id-7","SITEID":"JPN-1","AGE":54,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-1","INVNAM":"Dr. JPN-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.08724,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-10 08:49:00","TRT01SDTM":"2019-10-10 08:49:00","AP01SDTM":"2019-10-10 08:49:00","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":778,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.60813,"AVALU":"g/L","BASE2":2.76609,"BASE":2.99355,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15796,"PCHG2":-5.71049,"CHG":-0.38542,"PCHG":-12.87494,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-17 08:49:00","ADY":646,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-135","SUBJID":"id-135","SITEID":"JPN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.12703,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-12 13:29:09","TRT01SDTM":"2019-10-12 13:29:09","AP01SDTM":"2019-10-12 13:29:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2586,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.94188,"AVALU":"U/L","BASE2":22.94188,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2019-10-13 13:29:09","ADY":1,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-135","SUBJID":"id-135","SITEID":"JPN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.12703,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-12 13:29:09","TRT01SDTM":"2019-10-12 13:29:09","AP01SDTM":"2019-10-12 13:29:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8396,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.61236,"AVALU":"U/L","BASE2":22.94188,"BASE":4.61236,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-18.32952,"PCHG2":-79.89546,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2019-12-01 13:29:09","ADY":50,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-135","SUBJID":"id-135","SITEID":"JPN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.12703,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-12 13:29:09","TRT01SDTM":"2019-10-12 13:29:09","AP01SDTM":"2019-10-12 13:29:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":247,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.50998,"AVALU":"U/L","BASE2":22.94188,"BASE":4.61236,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.4319,"PCHG2":-71.62403,"CHG":1.89762,"PCHG":41.14209,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-3","BTOXGR":"-2","ADTM":"2019-12-07 13:29:09","ADY":56,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-135","SUBJID":"id-135","SITEID":"JPN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.12703,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-12 13:29:09","TRT01SDTM":"2019-10-12 13:29:09","AP01SDTM":"2019-10-12 13:29:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5944,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.89738,"AVALU":"U/L","BASE2":22.94188,"BASE":4.61236,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.0445,"PCHG2":-61.21774,"CHG":4.28502,"PCHG":92.90299,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-03-15 13:29:09","ADY":155,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-135","SUBJID":"id-135","SITEID":"JPN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.12703,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-12 13:29:09","TRT01SDTM":"2019-10-12 13:29:09","AP01SDTM":"2019-10-12 13:29:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":218,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.22106,"AVALU":"U/L","BASE2":22.94188,"BASE":4.61236,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-20.72083,"PCHG2":-90.31877,"CHG":-2.3913,"PCHG":-51.84555,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2020-06-05 13:29:09","ADY":237,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-135","SUBJID":"id-135","SITEID":"JPN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.12703,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-12 13:29:09","TRT01SDTM":"2019-10-12 13:29:09","AP01SDTM":"2019-10-12 13:29:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6544,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.89883,"AVALU":"U/L","BASE2":22.94188,"BASE":4.61236,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.04306,"PCHG2":-43.77608,"CHG":8.28647,"PCHG":179.65782,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-05-28 13:29:09","ADY":594,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-135","SUBJID":"id-135","SITEID":"JPN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.12703,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-12 13:29:09","TRT01SDTM":"2019-10-12 13:29:09","AP01SDTM":"2019-10-12 13:29:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7199,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.39632,"AVALU":"U/L","BASE2":22.94188,"BASE":4.61236,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.45443,"PCHG2":28.13385,"CHG":24.78396,"PCHG":537.3379,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-07-02 13:29:09","ADY":629,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-135","SUBJID":"id-135","SITEID":"JPN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.12703,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-12 13:29:09","TRT01SDTM":"2019-10-12 13:29:09","AP01SDTM":"2019-10-12 13:29:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5842,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.2139,"AVALU":"mg/L","BASE2":8.2139,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-1","ADTM":"2019-10-13 13:29:09","ADY":1,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-135","SUBJID":"id-135","SITEID":"JPN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.12703,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-12 13:29:09","TRT01SDTM":"2019-10-12 13:29:09","AP01SDTM":"2019-10-12 13:29:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1921,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.71051,"AVALU":"mg/L","BASE2":8.2139,"BASE":6.71051,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.50339,"PCHG2":-18.30295,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2019-12-01 13:29:09","ADY":50,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-135","SUBJID":"id-135","SITEID":"JPN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.12703,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-12 13:29:09","TRT01SDTM":"2019-10-12 13:29:09","AP01SDTM":"2019-10-12 13:29:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1489,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.33319,"AVALU":"mg/L","BASE2":8.2139,"BASE":6.71051,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1193,"PCHG2":1.45236,"CHG":1.62268,"PCHG":24.18118,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2019-12-07 13:29:09","ADY":56,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-135","SUBJID":"id-135","SITEID":"JPN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.12703,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-12 13:29:09","TRT01SDTM":"2019-10-12 13:29:09","AP01SDTM":"2019-10-12 13:29:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":836,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.99067,"AVALU":"mg/L","BASE2":8.2139,"BASE":6.71051,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.77677,"PCHG2":21.63131,"CHG":3.28016,"PCHG":48.88091,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-03-15 13:29:09","ADY":155,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-135","SUBJID":"id-135","SITEID":"JPN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.12703,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-12 13:29:09","TRT01SDTM":"2019-10-12 13:29:09","AP01SDTM":"2019-10-12 13:29:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":222,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.94371,"AVALU":"mg/L","BASE2":8.2139,"BASE":6.71051,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.72981,"PCHG2":8.88509,"CHG":2.2332,"PCHG":33.27909,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-06-05 13:29:09","ADY":237,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-135","SUBJID":"id-135","SITEID":"JPN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.12703,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-12 13:29:09","TRT01SDTM":"2019-10-12 13:29:09","AP01SDTM":"2019-10-12 13:29:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3037,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.42886,"AVALU":"mg/L","BASE2":8.2139,"BASE":6.71051,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.78504,"PCHG2":-9.55741,"CHG":0.71835,"PCHG":10.70485,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-2","BTOXGR":"-1","ADTM":"2021-05-28 13:29:09","ADY":594,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-135","SUBJID":"id-135","SITEID":"JPN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.12703,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-12 13:29:09","TRT01SDTM":"2019-10-12 13:29:09","AP01SDTM":"2019-10-12 13:29:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":440,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.48802,"AVALU":"mg/L","BASE2":8.2139,"BASE":6.71051,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.27412,"PCHG2":39.86078,"CHG":4.77751,"PCHG":71.19441,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"1","BTOXGR":"-1","ADTM":"2021-07-02 13:29:09","ADY":629,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-135","SUBJID":"id-135","SITEID":"JPN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.12703,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-12 13:29:09","TRT01SDTM":"2019-10-12 13:29:09","AP01SDTM":"2019-10-12 13:29:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4999,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.11502,"AVALU":"g/L","BASE2":3.11502,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"2","BTOXGR":"0","ADTM":"2019-10-13 13:29:09","ADY":1,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-135","SUBJID":"id-135","SITEID":"JPN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.12703,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-12 13:29:09","TRT01SDTM":"2019-10-12 13:29:09","AP01SDTM":"2019-10-12 13:29:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":49,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99248,"AVALU":"g/L","BASE2":3.11502,"BASE":2.99248,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.12255,"PCHG2":-3.93405,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-01 13:29:09","ADY":50,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-135","SUBJID":"id-135","SITEID":"JPN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.12703,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-12 13:29:09","TRT01SDTM":"2019-10-12 13:29:09","AP01SDTM":"2019-10-12 13:29:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5078,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02946,"AVALU":"g/L","BASE2":3.11502,"BASE":2.99248,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08557,"PCHG2":-2.74691,"CHG":0.03698,"PCHG":1.23576,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2019-12-07 13:29:09","ADY":56,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-135","SUBJID":"id-135","SITEID":"JPN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.12703,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-12 13:29:09","TRT01SDTM":"2019-10-12 13:29:09","AP01SDTM":"2019-10-12 13:29:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5240,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93243,"AVALU":"g/L","BASE2":3.11502,"BASE":2.99248,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18259,"PCHG2":-5.86175,"CHG":-0.06005,"PCHG":-2.00663,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-15 13:29:09","ADY":155,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-135","SUBJID":"id-135","SITEID":"JPN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.12703,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-12 13:29:09","TRT01SDTM":"2019-10-12 13:29:09","AP01SDTM":"2019-10-12 13:29:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1062,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.71695,"AVALU":"g/L","BASE2":3.11502,"BASE":2.99248,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.39808,"PCHG2":-12.77927,"CHG":-0.27553,"PCHG":-9.20744,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-05 13:29:09","ADY":237,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-135","SUBJID":"id-135","SITEID":"JPN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.12703,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-12 13:29:09","TRT01SDTM":"2019-10-12 13:29:09","AP01SDTM":"2019-10-12 13:29:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2862,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85831,"AVALU":"g/L","BASE2":3.11502,"BASE":2.99248,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.25672,"PCHG2":-8.2413,"CHG":-0.13417,"PCHG":-4.48364,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-28 13:29:09","ADY":594,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-135","SUBJID":"id-135","SITEID":"JPN-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.12703,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-09","TRTSDTM":"2019-10-12 13:29:09","TRT01SDTM":"2019-10-12 13:29:09","AP01SDTM":"2019-10-12 13:29:09","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2883,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96693,"AVALU":"g/L","BASE2":3.11502,"BASE":2.99248,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14809,"PCHG2":-4.75407,"CHG":-0.02554,"PCHG":-0.8536,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-02 13:29:09","ADY":629,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-373","SUBJID":"id-373","SITEID":"JPN-11","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.03424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-25 07:10:45","TRTEDTM":"2023-08-26 01:10:45","TRT01SDTM":"2020-08-25 07:10:45","TRT01EDTM":"2022-08-25 19:10:45","TRT02SDTM":"2022-08-25 19:10:45","TRT02EDTM":"2023-08-26 01:10:45","AP01SDTM":"2020-08-25 07:10:45","AP01EDTM":"2022-08-25 19:10:45","AP02SDTM":"2022-08-25 19:10:45","AP02EDTM":"2023-08-26 01:10:45","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-26","EOSDY":1096,"LSTALVDT":"2023-09-19","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1596,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.54145,"AVALU":"U/L","BASE2":34.54145,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-18 07:10:45","ADY":54,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-373","SUBJID":"id-373","SITEID":"JPN-11","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.03424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-25 07:10:45","TRTEDTM":"2023-08-26 01:10:45","TRT01SDTM":"2020-08-25 07:10:45","TRT01EDTM":"2022-08-25 19:10:45","TRT02SDTM":"2022-08-25 19:10:45","TRT02EDTM":"2023-08-26 01:10:45","AP01SDTM":"2020-08-25 07:10:45","AP01EDTM":"2022-08-25 19:10:45","AP02SDTM":"2022-08-25 19:10:45","AP02EDTM":"2023-08-26 01:10:45","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-26","EOSDY":1096,"LSTALVDT":"2023-09-19","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3398,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.38952,"AVALU":"U/L","BASE2":34.54145,"BASE":23.38952,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-11.15193,"PCHG2":-32.28565,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-25 07:10:45","ADY":243,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-373","SUBJID":"id-373","SITEID":"JPN-11","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.03424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-25 07:10:45","TRTEDTM":"2023-08-26 01:10:45","TRT01SDTM":"2020-08-25 07:10:45","TRT01EDTM":"2022-08-25 19:10:45","TRT02SDTM":"2022-08-25 19:10:45","TRT02EDTM":"2023-08-26 01:10:45","AP01SDTM":"2020-08-25 07:10:45","AP01EDTM":"2022-08-25 19:10:45","AP02SDTM":"2022-08-25 19:10:45","AP02EDTM":"2023-08-26 01:10:45","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-26","EOSDY":1096,"LSTALVDT":"2023-09-19","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4947,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.30371,"AVALU":"U/L","BASE2":34.54145,"BASE":23.38952,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-28.23774,"PCHG2":-81.75029,"CHG":-17.08581,"PCHG":-73.04898,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-06-12 07:10:45","ADY":291,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-373","SUBJID":"id-373","SITEID":"JPN-11","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.03424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-25 07:10:45","TRTEDTM":"2023-08-26 01:10:45","TRT01SDTM":"2020-08-25 07:10:45","TRT01EDTM":"2022-08-25 19:10:45","TRT02SDTM":"2022-08-25 19:10:45","TRT02EDTM":"2023-08-26 01:10:45","AP01SDTM":"2020-08-25 07:10:45","AP01EDTM":"2022-08-25 19:10:45","AP02SDTM":"2022-08-25 19:10:45","AP02EDTM":"2023-08-26 01:10:45","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-26","EOSDY":1096,"LSTALVDT":"2023-09-19","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1198,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.30309,"AVALU":"U/L","BASE2":34.54145,"BASE":23.38952,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.23836,"PCHG2":-38.32601,"CHG":-2.08643,"PCHG":-8.92036,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-08 07:10:45","ADY":317,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-373","SUBJID":"id-373","SITEID":"JPN-11","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.03424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-25 07:10:45","TRTEDTM":"2023-08-26 01:10:45","TRT01SDTM":"2020-08-25 07:10:45","TRT01EDTM":"2022-08-25 19:10:45","TRT02SDTM":"2022-08-25 19:10:45","TRT02EDTM":"2023-08-26 01:10:45","AP01SDTM":"2020-08-25 07:10:45","AP01EDTM":"2022-08-25 19:10:45","AP02SDTM":"2022-08-25 19:10:45","AP02EDTM":"2023-08-26 01:10:45","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-26","EOSDY":1096,"LSTALVDT":"2023-09-19","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":576,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.00933,"AVALU":"U/L","BASE2":34.54145,"BASE":23.38952,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-19.53212,"PCHG2":-56.5469,"CHG":-8.38019,"PCHG":-35.82882,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-28 07:10:45","ADY":552,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-373","SUBJID":"id-373","SITEID":"JPN-11","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.03424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-25 07:10:45","TRTEDTM":"2023-08-26 01:10:45","TRT01SDTM":"2020-08-25 07:10:45","TRT01EDTM":"2022-08-25 19:10:45","TRT02SDTM":"2022-08-25 19:10:45","TRT02EDTM":"2023-08-26 01:10:45","AP01SDTM":"2020-08-25 07:10:45","AP01EDTM":"2022-08-25 19:10:45","AP02SDTM":"2022-08-25 19:10:45","AP02EDTM":"2023-08-26 01:10:45","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-26","EOSDY":1096,"LSTALVDT":"2023-09-19","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3424,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.65365,"AVALU":"U/L","BASE2":34.54145,"BASE":23.38952,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.8878,"PCHG2":-34.41603,"CHG":-0.73587,"PCHG":-3.14614,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-03 07:10:45","ADY":800,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-373","SUBJID":"id-373","SITEID":"JPN-11","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.03424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-25 07:10:45","TRTEDTM":"2023-08-26 01:10:45","TRT01SDTM":"2020-08-25 07:10:45","TRT01EDTM":"2022-08-25 19:10:45","TRT02SDTM":"2022-08-25 19:10:45","TRT02EDTM":"2023-08-26 01:10:45","AP01SDTM":"2020-08-25 07:10:45","AP01EDTM":"2022-08-25 19:10:45","AP02SDTM":"2022-08-25 19:10:45","AP02EDTM":"2023-08-26 01:10:45","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-26","EOSDY":1096,"LSTALVDT":"2023-09-19","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7770,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.7761,"AVALU":"U/L","BASE2":34.54145,"BASE":23.38952,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.76535,"PCHG2":-42.74676,"CHG":-3.61342,"PCHG":-15.44888,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-12 07:10:45","ADY":1082,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-373","SUBJID":"id-373","SITEID":"JPN-11","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.03424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-25 07:10:45","TRTEDTM":"2023-08-26 01:10:45","TRT01SDTM":"2020-08-25 07:10:45","TRT01EDTM":"2022-08-25 19:10:45","TRT02SDTM":"2022-08-25 19:10:45","TRT02EDTM":"2023-08-26 01:10:45","AP01SDTM":"2020-08-25 07:10:45","AP01EDTM":"2022-08-25 19:10:45","AP02SDTM":"2022-08-25 19:10:45","AP02EDTM":"2023-08-26 01:10:45","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-26","EOSDY":1096,"LSTALVDT":"2023-09-19","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8151,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.96229,"AVALU":"mg/L","BASE2":8.96229,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-10-18 07:10:45","ADY":54,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-373","SUBJID":"id-373","SITEID":"JPN-11","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.03424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-25 07:10:45","TRTEDTM":"2023-08-26 01:10:45","TRT01SDTM":"2020-08-25 07:10:45","TRT01EDTM":"2022-08-25 19:10:45","TRT02SDTM":"2022-08-25 19:10:45","TRT02EDTM":"2023-08-26 01:10:45","AP01SDTM":"2020-08-25 07:10:45","AP01EDTM":"2022-08-25 19:10:45","AP02SDTM":"2022-08-25 19:10:45","AP02EDTM":"2023-08-26 01:10:45","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-26","EOSDY":1096,"LSTALVDT":"2023-09-19","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1593,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.53767,"AVALU":"mg/L","BASE2":8.96229,"BASE":7.53767,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.42462,"PCHG2":-15.89575,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2021-04-25 07:10:45","ADY":243,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-373","SUBJID":"id-373","SITEID":"JPN-11","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.03424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-25 07:10:45","TRTEDTM":"2023-08-26 01:10:45","TRT01SDTM":"2020-08-25 07:10:45","TRT01EDTM":"2022-08-25 19:10:45","TRT02SDTM":"2022-08-25 19:10:45","TRT02EDTM":"2023-08-26 01:10:45","AP01SDTM":"2020-08-25 07:10:45","AP01EDTM":"2022-08-25 19:10:45","AP02SDTM":"2022-08-25 19:10:45","AP02EDTM":"2023-08-26 01:10:45","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-26","EOSDY":1096,"LSTALVDT":"2023-09-19","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2763,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.05704,"AVALU":"mg/L","BASE2":8.96229,"BASE":7.53767,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09476,"PCHG2":1.05728,"CHG":1.51938,"PCHG":20.15715,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-06-12 07:10:45","ADY":291,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-373","SUBJID":"id-373","SITEID":"JPN-11","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.03424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-25 07:10:45","TRTEDTM":"2023-08-26 01:10:45","TRT01SDTM":"2020-08-25 07:10:45","TRT01EDTM":"2022-08-25 19:10:45","TRT02SDTM":"2022-08-25 19:10:45","TRT02EDTM":"2023-08-26 01:10:45","AP01SDTM":"2020-08-25 07:10:45","AP01EDTM":"2022-08-25 19:10:45","AP02SDTM":"2022-08-25 19:10:45","AP02EDTM":"2023-08-26 01:10:45","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-26","EOSDY":1096,"LSTALVDT":"2023-09-19","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2020,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.01616,"AVALU":"mg/L","BASE2":8.96229,"BASE":7.53767,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.05387,"PCHG2":11.75894,"CHG":2.47849,"PCHG":32.88144,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"4","BTOXGR":"-1","ADTM":"2021-07-08 07:10:45","ADY":317,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-373","SUBJID":"id-373","SITEID":"JPN-11","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.03424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-25 07:10:45","TRTEDTM":"2023-08-26 01:10:45","TRT01SDTM":"2020-08-25 07:10:45","TRT01EDTM":"2022-08-25 19:10:45","TRT02SDTM":"2022-08-25 19:10:45","TRT02EDTM":"2023-08-26 01:10:45","AP01SDTM":"2020-08-25 07:10:45","AP01EDTM":"2022-08-25 19:10:45","AP02SDTM":"2022-08-25 19:10:45","AP02EDTM":"2023-08-26 01:10:45","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-26","EOSDY":1096,"LSTALVDT":"2023-09-19","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4398,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.48453,"AVALU":"mg/L","BASE2":8.96229,"BASE":7.53767,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.47776,"PCHG2":-5.33074,"CHG":0.94687,"PCHG":12.5618,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-02-28 07:10:45","ADY":552,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-373","SUBJID":"id-373","SITEID":"JPN-11","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.03424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-25 07:10:45","TRTEDTM":"2023-08-26 01:10:45","TRT01SDTM":"2020-08-25 07:10:45","TRT01EDTM":"2022-08-25 19:10:45","TRT02SDTM":"2022-08-25 19:10:45","TRT02EDTM":"2023-08-26 01:10:45","AP01SDTM":"2020-08-25 07:10:45","AP01EDTM":"2022-08-25 19:10:45","AP02SDTM":"2022-08-25 19:10:45","AP02EDTM":"2023-08-26 01:10:45","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-26","EOSDY":1096,"LSTALVDT":"2023-09-19","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1101,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.17274,"AVALU":"mg/L","BASE2":8.96229,"BASE":7.53767,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.21045,"PCHG2":13.50609,"CHG":2.63508,"PCHG":34.9588,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"1","BTOXGR":"-1","ADTM":"2022-11-03 07:10:45","ADY":800,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-373","SUBJID":"id-373","SITEID":"JPN-11","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.03424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-25 07:10:45","TRTEDTM":"2023-08-26 01:10:45","TRT01SDTM":"2020-08-25 07:10:45","TRT01EDTM":"2022-08-25 19:10:45","TRT02SDTM":"2022-08-25 19:10:45","TRT02EDTM":"2023-08-26 01:10:45","AP01SDTM":"2020-08-25 07:10:45","AP01EDTM":"2022-08-25 19:10:45","AP02SDTM":"2022-08-25 19:10:45","AP02EDTM":"2023-08-26 01:10:45","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-26","EOSDY":1096,"LSTALVDT":"2023-09-19","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6951,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.9315,"AVALU":"mg/L","BASE2":8.96229,"BASE":7.53767,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03079,"PCHG2":-0.34359,"CHG":1.39383,"PCHG":18.49153,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2023-08-12 07:10:45","ADY":1082,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-373","SUBJID":"id-373","SITEID":"JPN-11","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.03424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-25 07:10:45","TRTEDTM":"2023-08-26 01:10:45","TRT01SDTM":"2020-08-25 07:10:45","TRT01EDTM":"2022-08-25 19:10:45","TRT02SDTM":"2022-08-25 19:10:45","TRT02EDTM":"2023-08-26 01:10:45","AP01SDTM":"2020-08-25 07:10:45","AP01EDTM":"2022-08-25 19:10:45","AP02SDTM":"2022-08-25 19:10:45","AP02EDTM":"2023-08-26 01:10:45","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-26","EOSDY":1096,"LSTALVDT":"2023-09-19","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7125,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9316,"AVALU":"g/L","BASE2":2.9316,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-18 07:10:45","ADY":54,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-373","SUBJID":"id-373","SITEID":"JPN-11","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.03424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-25 07:10:45","TRTEDTM":"2023-08-26 01:10:45","TRT01SDTM":"2020-08-25 07:10:45","TRT01EDTM":"2022-08-25 19:10:45","TRT02SDTM":"2022-08-25 19:10:45","TRT02EDTM":"2023-08-26 01:10:45","AP01SDTM":"2020-08-25 07:10:45","AP01EDTM":"2022-08-25 19:10:45","AP02SDTM":"2022-08-25 19:10:45","AP02EDTM":"2023-08-26 01:10:45","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-26","EOSDY":1096,"LSTALVDT":"2023-09-19","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6786,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8374,"AVALU":"g/L","BASE2":2.9316,"BASE":2.8374,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.0942,"PCHG2":-3.2132,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-25 07:10:45","ADY":243,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-373","SUBJID":"id-373","SITEID":"JPN-11","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.03424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-25 07:10:45","TRTEDTM":"2023-08-26 01:10:45","TRT01SDTM":"2020-08-25 07:10:45","TRT01EDTM":"2022-08-25 19:10:45","TRT02SDTM":"2022-08-25 19:10:45","TRT02EDTM":"2023-08-26 01:10:45","AP01SDTM":"2020-08-25 07:10:45","AP01EDTM":"2022-08-25 19:10:45","AP02SDTM":"2022-08-25 19:10:45","AP02EDTM":"2023-08-26 01:10:45","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-26","EOSDY":1096,"LSTALVDT":"2023-09-19","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7377,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95696,"AVALU":"g/L","BASE2":2.9316,"BASE":2.8374,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02537,"PCHG2":0.86532,"CHG":0.11957,"PCHG":4.21393,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-12 07:10:45","ADY":291,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-373","SUBJID":"id-373","SITEID":"JPN-11","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.03424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-25 07:10:45","TRTEDTM":"2023-08-26 01:10:45","TRT01SDTM":"2020-08-25 07:10:45","TRT01EDTM":"2022-08-25 19:10:45","TRT02SDTM":"2022-08-25 19:10:45","TRT02EDTM":"2023-08-26 01:10:45","AP01SDTM":"2020-08-25 07:10:45","AP01EDTM":"2022-08-25 19:10:45","AP02SDTM":"2022-08-25 19:10:45","AP02EDTM":"2023-08-26 01:10:45","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-26","EOSDY":1096,"LSTALVDT":"2023-09-19","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5614,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85972,"AVALU":"g/L","BASE2":2.9316,"BASE":2.8374,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07187,"PCHG2":-2.45161,"CHG":0.02233,"PCHG":0.78688,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-08 07:10:45","ADY":317,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-373","SUBJID":"id-373","SITEID":"JPN-11","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.03424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-25 07:10:45","TRTEDTM":"2023-08-26 01:10:45","TRT01SDTM":"2020-08-25 07:10:45","TRT01EDTM":"2022-08-25 19:10:45","TRT02SDTM":"2022-08-25 19:10:45","TRT02EDTM":"2023-08-26 01:10:45","AP01SDTM":"2020-08-25 07:10:45","AP01EDTM":"2022-08-25 19:10:45","AP02SDTM":"2022-08-25 19:10:45","AP02EDTM":"2023-08-26 01:10:45","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-26","EOSDY":1096,"LSTALVDT":"2023-09-19","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2782,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94255,"AVALU":"g/L","BASE2":2.9316,"BASE":2.8374,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01095,"PCHG2":0.37357,"CHG":0.10515,"PCHG":3.70584,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-28 07:10:45","ADY":552,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-373","SUBJID":"id-373","SITEID":"JPN-11","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.03424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-25 07:10:45","TRTEDTM":"2023-08-26 01:10:45","TRT01SDTM":"2020-08-25 07:10:45","TRT01EDTM":"2022-08-25 19:10:45","TRT02SDTM":"2022-08-25 19:10:45","TRT02EDTM":"2023-08-26 01:10:45","AP01SDTM":"2020-08-25 07:10:45","AP01EDTM":"2022-08-25 19:10:45","AP02SDTM":"2022-08-25 19:10:45","AP02EDTM":"2023-08-26 01:10:45","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-26","EOSDY":1096,"LSTALVDT":"2023-09-19","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3365,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84372,"AVALU":"g/L","BASE2":2.9316,"BASE":2.8374,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08788,"PCHG2":-2.99769,"CHG":0.00632,"PCHG":0.22266,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-03 07:10:45","ADY":800,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-373","SUBJID":"id-373","SITEID":"JPN-11","AGE":45,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.03424,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-22","TRTSDTM":"2020-08-25 07:10:45","TRTEDTM":"2023-08-26 01:10:45","TRT01SDTM":"2020-08-25 07:10:45","TRT01EDTM":"2022-08-25 19:10:45","TRT02SDTM":"2022-08-25 19:10:45","TRT02EDTM":"2023-08-26 01:10:45","AP01SDTM":"2020-08-25 07:10:45","AP01EDTM":"2022-08-25 19:10:45","AP02SDTM":"2022-08-25 19:10:45","AP02EDTM":"2023-08-26 01:10:45","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-26","EOSDY":1096,"LSTALVDT":"2023-09-19","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6353,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91036,"AVALU":"g/L","BASE2":2.9316,"BASE":2.8374,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02124,"PCHG2":-0.72452,"CHG":0.07296,"PCHG":2.5713,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-12 07:10:45","ADY":1082,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-61","SUBJID":"id-61","SITEID":"JPN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.00869,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 00:39:24","TRTEDTM":"2023-12-22 18:39:24","TRT01SDTM":"2020-12-22 00:39:24","TRT01EDTM":"2022-12-22 12:39:24","TRT02SDTM":"2022-12-22 12:39:24","TRT02EDTM":"2023-12-22 18:39:24","AP01SDTM":"2020-12-22 00:39:24","AP01EDTM":"2022-12-22 12:39:24","AP02SDTM":"2022-12-22 12:39:24","AP02EDTM":"2023-12-22 18:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4643,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.11278,"AVALU":"U/L","BASE2":14.11278,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-08 00:39:24","ADY":107,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-61","SUBJID":"id-61","SITEID":"JPN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.00869,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 00:39:24","TRTEDTM":"2023-12-22 18:39:24","TRT01SDTM":"2020-12-22 00:39:24","TRT01EDTM":"2022-12-22 12:39:24","TRT02SDTM":"2022-12-22 12:39:24","TRT02EDTM":"2023-12-22 18:39:24","AP01SDTM":"2020-12-22 00:39:24","AP01EDTM":"2022-12-22 12:39:24","AP02SDTM":"2022-12-22 12:39:24","AP02EDTM":"2023-12-22 18:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7732,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.93618,"AVALU":"U/L","BASE2":14.11278,"BASE":18.93618,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":4.8234,"PCHG2":34.17753,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-12 00:39:24","ADY":172,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-61","SUBJID":"id-61","SITEID":"JPN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.00869,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 00:39:24","TRTEDTM":"2023-12-22 18:39:24","TRT01SDTM":"2020-12-22 00:39:24","TRT01EDTM":"2022-12-22 12:39:24","TRT02SDTM":"2022-12-22 12:39:24","TRT02EDTM":"2023-12-22 18:39:24","AP01SDTM":"2020-12-22 00:39:24","AP01EDTM":"2022-12-22 12:39:24","AP02SDTM":"2022-12-22 12:39:24","AP02EDTM":"2023-12-22 18:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":48,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.31388,"AVALU":"U/L","BASE2":14.11278,"BASE":18.93618,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.7989,"PCHG2":-48.17546,"CHG":-11.62229,"PCHG":-61.37614,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-06 00:39:24","ADY":439,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-61","SUBJID":"id-61","SITEID":"JPN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.00869,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 00:39:24","TRTEDTM":"2023-12-22 18:39:24","TRT01SDTM":"2020-12-22 00:39:24","TRT01EDTM":"2022-12-22 12:39:24","TRT02SDTM":"2022-12-22 12:39:24","TRT02EDTM":"2023-12-22 18:39:24","AP01SDTM":"2020-12-22 00:39:24","AP01EDTM":"2022-12-22 12:39:24","AP02SDTM":"2022-12-22 12:39:24","AP02EDTM":"2023-12-22 18:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3546,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.47098,"AVALU":"U/L","BASE2":14.11278,"BASE":18.93618,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.6418,"PCHG2":-18.7192,"CHG":-7.4652,"PCHG":-39.42294,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-05 00:39:24","ADY":469,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-61","SUBJID":"id-61","SITEID":"JPN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.00869,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 00:39:24","TRTEDTM":"2023-12-22 18:39:24","TRT01SDTM":"2020-12-22 00:39:24","TRT01EDTM":"2022-12-22 12:39:24","TRT02SDTM":"2022-12-22 12:39:24","TRT02EDTM":"2023-12-22 18:39:24","AP01SDTM":"2020-12-22 00:39:24","AP01EDTM":"2022-12-22 12:39:24","AP02SDTM":"2022-12-22 12:39:24","AP02EDTM":"2023-12-22 18:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8250,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.07447,"AVALU":"U/L","BASE2":14.11278,"BASE":18.93618,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.96169,"PCHG2":42.24324,"CHG":1.1383,"PCHG":6.01123,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-15 00:39:24","ADY":479,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-61","SUBJID":"id-61","SITEID":"JPN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.00869,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 00:39:24","TRTEDTM":"2023-12-22 18:39:24","TRT01SDTM":"2020-12-22 00:39:24","TRT01EDTM":"2022-12-22 12:39:24","TRT02SDTM":"2022-12-22 12:39:24","TRT02EDTM":"2023-12-22 18:39:24","AP01SDTM":"2020-12-22 00:39:24","AP01EDTM":"2022-12-22 12:39:24","AP02SDTM":"2022-12-22 12:39:24","AP02EDTM":"2023-12-22 18:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5338,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.75087,"AVALU":"U/L","BASE2":14.11278,"BASE":18.93618,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.3619,"PCHG2":-30.90748,"CHG":-9.1853,"PCHG":-48.50664,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-03 00:39:24","ADY":558,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-61","SUBJID":"id-61","SITEID":"JPN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.00869,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 00:39:24","TRTEDTM":"2023-12-22 18:39:24","TRT01SDTM":"2020-12-22 00:39:24","TRT01EDTM":"2022-12-22 12:39:24","TRT02SDTM":"2022-12-22 12:39:24","TRT02EDTM":"2023-12-22 18:39:24","AP01SDTM":"2020-12-22 00:39:24","AP01EDTM":"2022-12-22 12:39:24","AP02SDTM":"2022-12-22 12:39:24","AP02EDTM":"2023-12-22 18:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1993,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.37468,"AVALU":"U/L","BASE2":14.11278,"BASE":18.93618,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.26191,"PCHG2":37.28469,"CHG":0.43851,"PCHG":2.31571,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-12-05 00:39:24","ADY":1078,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-61","SUBJID":"id-61","SITEID":"JPN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.00869,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 00:39:24","TRTEDTM":"2023-12-22 18:39:24","TRT01SDTM":"2020-12-22 00:39:24","TRT01EDTM":"2022-12-22 12:39:24","TRT02SDTM":"2022-12-22 12:39:24","TRT02EDTM":"2023-12-22 18:39:24","AP01SDTM":"2020-12-22 00:39:24","AP01EDTM":"2022-12-22 12:39:24","AP02SDTM":"2022-12-22 12:39:24","AP02EDTM":"2023-12-22 18:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4038,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.47435,"AVALU":"mg/L","BASE2":8.47435,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-08 00:39:24","ADY":107,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-61","SUBJID":"id-61","SITEID":"JPN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.00869,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 00:39:24","TRTEDTM":"2023-12-22 18:39:24","TRT01SDTM":"2020-12-22 00:39:24","TRT01EDTM":"2022-12-22 12:39:24","TRT02SDTM":"2022-12-22 12:39:24","TRT02EDTM":"2023-12-22 18:39:24","AP01SDTM":"2020-12-22 00:39:24","AP01EDTM":"2022-12-22 12:39:24","AP02SDTM":"2022-12-22 12:39:24","AP02EDTM":"2023-12-22 18:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4285,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.30021,"AVALU":"mg/L","BASE2":8.47435,"BASE":9.30021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.82585,"PCHG2":9.74532,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-12 00:39:24","ADY":172,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-61","SUBJID":"id-61","SITEID":"JPN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.00869,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 00:39:24","TRTEDTM":"2023-12-22 18:39:24","TRT01SDTM":"2020-12-22 00:39:24","TRT01EDTM":"2022-12-22 12:39:24","TRT02SDTM":"2022-12-22 12:39:24","TRT02EDTM":"2023-12-22 18:39:24","AP01SDTM":"2020-12-22 00:39:24","AP01EDTM":"2022-12-22 12:39:24","AP02SDTM":"2022-12-22 12:39:24","AP02EDTM":"2023-12-22 18:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3458,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.94358,"AVALU":"mg/L","BASE2":8.47435,"BASE":9.30021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.46923,"PCHG2":5.53703,"CHG":-0.35663,"PCHG":-3.83459,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-06 00:39:24","ADY":439,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-61","SUBJID":"id-61","SITEID":"JPN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.00869,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 00:39:24","TRTEDTM":"2023-12-22 18:39:24","TRT01SDTM":"2020-12-22 00:39:24","TRT01EDTM":"2022-12-22 12:39:24","TRT02SDTM":"2022-12-22 12:39:24","TRT02EDTM":"2023-12-22 18:39:24","AP01SDTM":"2020-12-22 00:39:24","AP01EDTM":"2022-12-22 12:39:24","AP02SDTM":"2022-12-22 12:39:24","AP02EDTM":"2023-12-22 18:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4405,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.03801,"AVALU":"mg/L","BASE2":8.47435,"BASE":9.30021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.56365,"PCHG2":6.65126,"CHG":-0.2622,"PCHG":-2.81931,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-05 00:39:24","ADY":469,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-61","SUBJID":"id-61","SITEID":"JPN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.00869,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 00:39:24","TRTEDTM":"2023-12-22 18:39:24","TRT01SDTM":"2020-12-22 00:39:24","TRT01EDTM":"2022-12-22 12:39:24","TRT02SDTM":"2022-12-22 12:39:24","TRT02EDTM":"2023-12-22 18:39:24","AP01SDTM":"2020-12-22 00:39:24","AP01EDTM":"2022-12-22 12:39:24","AP02SDTM":"2022-12-22 12:39:24","AP02EDTM":"2023-12-22 18:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6159,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.56449,"AVALU":"mg/L","BASE2":8.47435,"BASE":9.30021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.09013,"PCHG2":12.86391,"CHG":0.26428,"PCHG":2.84166,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-15 00:39:24","ADY":479,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-61","SUBJID":"id-61","SITEID":"JPN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.00869,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 00:39:24","TRTEDTM":"2023-12-22 18:39:24","TRT01SDTM":"2020-12-22 00:39:24","TRT01EDTM":"2022-12-22 12:39:24","TRT02SDTM":"2022-12-22 12:39:24","TRT02EDTM":"2023-12-22 18:39:24","AP01SDTM":"2020-12-22 00:39:24","AP01EDTM":"2022-12-22 12:39:24","AP02SDTM":"2022-12-22 12:39:24","AP02EDTM":"2023-12-22 18:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6982,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.53007,"AVALU":"mg/L","BASE2":8.47435,"BASE":9.30021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05572,"PCHG2":0.6575,"CHG":-0.77013,"PCHG":-8.28083,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-03 00:39:24","ADY":558,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-61","SUBJID":"id-61","SITEID":"JPN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.00869,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 00:39:24","TRTEDTM":"2023-12-22 18:39:24","TRT01SDTM":"2020-12-22 00:39:24","TRT01EDTM":"2022-12-22 12:39:24","TRT02SDTM":"2022-12-22 12:39:24","TRT02EDTM":"2023-12-22 18:39:24","AP01SDTM":"2020-12-22 00:39:24","AP01EDTM":"2022-12-22 12:39:24","AP02SDTM":"2022-12-22 12:39:24","AP02EDTM":"2023-12-22 18:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6389,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.84645,"AVALU":"mg/L","BASE2":8.47435,"BASE":9.30021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.3721,"PCHG2":4.39086,"CHG":-0.45376,"PCHG":-4.87899,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-12-05 00:39:24","ADY":1078,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-61","SUBJID":"id-61","SITEID":"JPN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.00869,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 00:39:24","TRTEDTM":"2023-12-22 18:39:24","TRT01SDTM":"2020-12-22 00:39:24","TRT01EDTM":"2022-12-22 12:39:24","TRT02SDTM":"2022-12-22 12:39:24","TRT02EDTM":"2023-12-22 18:39:24","AP01SDTM":"2020-12-22 00:39:24","AP01EDTM":"2022-12-22 12:39:24","AP02SDTM":"2022-12-22 12:39:24","AP02EDTM":"2023-12-22 18:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4970,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86693,"AVALU":"g/L","BASE2":2.86693,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-08 00:39:24","ADY":107,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-61","SUBJID":"id-61","SITEID":"JPN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.00869,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 00:39:24","TRTEDTM":"2023-12-22 18:39:24","TRT01SDTM":"2020-12-22 00:39:24","TRT01EDTM":"2022-12-22 12:39:24","TRT02SDTM":"2022-12-22 12:39:24","TRT02EDTM":"2023-12-22 18:39:24","AP01SDTM":"2020-12-22 00:39:24","AP01EDTM":"2022-12-22 12:39:24","AP02SDTM":"2022-12-22 12:39:24","AP02EDTM":"2023-12-22 18:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":500,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75021,"AVALU":"g/L","BASE2":2.86693,"BASE":2.75021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.11672,"PCHG2":-4.07128,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-12 00:39:24","ADY":172,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-61","SUBJID":"id-61","SITEID":"JPN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.00869,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 00:39:24","TRTEDTM":"2023-12-22 18:39:24","TRT01SDTM":"2020-12-22 00:39:24","TRT01EDTM":"2022-12-22 12:39:24","TRT02SDTM":"2022-12-22 12:39:24","TRT02EDTM":"2023-12-22 18:39:24","AP01SDTM":"2020-12-22 00:39:24","AP01EDTM":"2022-12-22 12:39:24","AP02SDTM":"2022-12-22 12:39:24","AP02EDTM":"2023-12-22 18:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3101,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82733,"AVALU":"g/L","BASE2":2.86693,"BASE":2.75021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0396,"PCHG2":-1.38123,"CHG":0.07712,"PCHG":2.80421,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-06 00:39:24","ADY":439,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-61","SUBJID":"id-61","SITEID":"JPN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.00869,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 00:39:24","TRTEDTM":"2023-12-22 18:39:24","TRT01SDTM":"2020-12-22 00:39:24","TRT01EDTM":"2022-12-22 12:39:24","TRT02SDTM":"2022-12-22 12:39:24","TRT02EDTM":"2023-12-22 18:39:24","AP01SDTM":"2020-12-22 00:39:24","AP01EDTM":"2022-12-22 12:39:24","AP02SDTM":"2022-12-22 12:39:24","AP02EDTM":"2023-12-22 18:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3664,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93784,"AVALU":"g/L","BASE2":2.86693,"BASE":2.75021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07092,"PCHG2":2.47356,"CHG":0.18764,"PCHG":6.82261,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-05 00:39:24","ADY":469,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-61","SUBJID":"id-61","SITEID":"JPN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.00869,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 00:39:24","TRTEDTM":"2023-12-22 18:39:24","TRT01SDTM":"2020-12-22 00:39:24","TRT01EDTM":"2022-12-22 12:39:24","TRT02SDTM":"2022-12-22 12:39:24","TRT02EDTM":"2023-12-22 18:39:24","AP01SDTM":"2020-12-22 00:39:24","AP01EDTM":"2022-12-22 12:39:24","AP02SDTM":"2022-12-22 12:39:24","AP02EDTM":"2023-12-22 18:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8272,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03745,"AVALU":"g/L","BASE2":2.86693,"BASE":2.75021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17052,"PCHG2":5.94776,"CHG":0.28724,"PCHG":10.44426,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-04-15 00:39:24","ADY":479,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-61","SUBJID":"id-61","SITEID":"JPN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.00869,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 00:39:24","TRTEDTM":"2023-12-22 18:39:24","TRT01SDTM":"2020-12-22 00:39:24","TRT01EDTM":"2022-12-22 12:39:24","TRT02SDTM":"2022-12-22 12:39:24","TRT02EDTM":"2023-12-22 18:39:24","AP01SDTM":"2020-12-22 00:39:24","AP01EDTM":"2022-12-22 12:39:24","AP02SDTM":"2022-12-22 12:39:24","AP02EDTM":"2023-12-22 18:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3880,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81815,"AVALU":"g/L","BASE2":2.86693,"BASE":2.75021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04877,"PCHG2":-1.70124,"CHG":0.06795,"PCHG":2.47062,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-03 00:39:24","ADY":558,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-11-id-61","SUBJID":"id-61","SITEID":"JPN-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-11","INVNAM":"Dr. JPN-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":14.00869,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-12-18","TRTSDTM":"2020-12-22 00:39:24","TRTEDTM":"2023-12-22 18:39:24","TRT01SDTM":"2020-12-22 00:39:24","TRT01EDTM":"2022-12-22 12:39:24","TRT02SDTM":"2022-12-22 12:39:24","TRT02EDTM":"2023-12-22 18:39:24","AP01SDTM":"2020-12-22 00:39:24","AP01EDTM":"2022-12-22 12:39:24","AP02SDTM":"2022-12-22 12:39:24","AP02EDTM":"2023-12-22 18:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-22","EOSDY":1096,"LSTALVDT":"2024-01-14","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":87,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.70304,"AVALU":"g/L","BASE2":2.86693,"BASE":2.75021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16388,"PCHG2":-5.71638,"CHG":-0.04716,"PCHG":-1.71492,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-12-05 00:39:24","ADY":1078,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-12-id-219","SUBJID":"id-219","SITEID":"JPN-12","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-12","INVNAM":"Dr. JPN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.39188,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 05:02:53","TRTEDTM":"2022-02-13 11:00:51","TRT01SDTM":"2020-05-03 05:02:53","TRT01EDTM":"2021-02-13 05:00:51","TRT02SDTM":"2021-02-13 05:00:51","TRT02EDTM":"2022-02-13 11:00:51","AP01SDTM":"2020-05-03 05:02:53","AP01EDTM":"2021-02-13 05:00:51","AP02SDTM":"2021-02-13 05:00:51","AP02EDTM":"2022-02-13 11:00:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":652,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7622,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.00165,"AVALU":"U/L","BASE2":2.00165,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-1","ADTM":"2020-05-14 05:02:53","ADY":11,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-12-id-219","SUBJID":"id-219","SITEID":"JPN-12","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-12","INVNAM":"Dr. JPN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.39188,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 05:02:53","TRTEDTM":"2022-02-13 11:00:51","TRT01SDTM":"2020-05-03 05:02:53","TRT01EDTM":"2021-02-13 05:00:51","TRT02SDTM":"2021-02-13 05:00:51","TRT02EDTM":"2022-02-13 11:00:51","AP01SDTM":"2020-05-03 05:02:53","AP01EDTM":"2021-02-13 05:00:51","AP02SDTM":"2021-02-13 05:00:51","AP02EDTM":"2022-02-13 11:00:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":652,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2950,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.08827,"AVALU":"U/L","BASE2":2.00165,"BASE":5.08827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":3.08662,"PCHG2":154.20363,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2021-01-05 05:02:53","ADY":247,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-12-id-219","SUBJID":"id-219","SITEID":"JPN-12","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-12","INVNAM":"Dr. JPN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.39188,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 05:02:53","TRTEDTM":"2022-02-13 11:00:51","TRT01SDTM":"2020-05-03 05:02:53","TRT01EDTM":"2021-02-13 05:00:51","TRT02SDTM":"2021-02-13 05:00:51","TRT02EDTM":"2022-02-13 11:00:51","AP01SDTM":"2020-05-03 05:02:53","AP01EDTM":"2021-02-13 05:00:51","AP02SDTM":"2021-02-13 05:00:51","AP02EDTM":"2022-02-13 11:00:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":652,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3556,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.57656,"AVALU":"U/L","BASE2":2.00165,"BASE":5.08827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.57491,"PCHG2":927.9803,"CHG":15.4883,"PCHG":304.39245,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-02-24 05:02:53","ADY":297,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-12-id-219","SUBJID":"id-219","SITEID":"JPN-12","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-12","INVNAM":"Dr. JPN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.39188,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 05:02:53","TRTEDTM":"2022-02-13 11:00:51","TRT01SDTM":"2020-05-03 05:02:53","TRT01EDTM":"2021-02-13 05:00:51","TRT02SDTM":"2021-02-13 05:00:51","TRT02EDTM":"2022-02-13 11:00:51","AP01SDTM":"2020-05-03 05:02:53","AP01EDTM":"2021-02-13 05:00:51","AP02SDTM":"2021-02-13 05:00:51","AP02EDTM":"2022-02-13 11:00:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":652,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8166,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.05652,"AVALU":"U/L","BASE2":2.00165,"BASE":5.08827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":22.05487,"PCHG2":1101.83465,"CHG":18.96825,"PCHG":372.78421,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-08-29 05:02:53","ADY":483,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-12-id-219","SUBJID":"id-219","SITEID":"JPN-12","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-12","INVNAM":"Dr. JPN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.39188,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 05:02:53","TRTEDTM":"2022-02-13 11:00:51","TRT01SDTM":"2020-05-03 05:02:53","TRT01EDTM":"2021-02-13 05:00:51","TRT02SDTM":"2021-02-13 05:00:51","TRT02EDTM":"2022-02-13 11:00:51","AP01SDTM":"2020-05-03 05:02:53","AP01EDTM":"2021-02-13 05:00:51","AP02SDTM":"2021-02-13 05:00:51","AP02EDTM":"2022-02-13 11:00:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":652,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7043,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.68335,"AVALU":"U/L","BASE2":2.00165,"BASE":5.08827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.6817,"PCHG2":783.43898,"CHG":12.59509,"PCHG":247.53201,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-09-07 05:02:53","ADY":492,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-12-id-219","SUBJID":"id-219","SITEID":"JPN-12","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-12","INVNAM":"Dr. JPN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.39188,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 05:02:53","TRTEDTM":"2022-02-13 11:00:51","TRT01SDTM":"2020-05-03 05:02:53","TRT01EDTM":"2021-02-13 05:00:51","TRT02SDTM":"2021-02-13 05:00:51","TRT02EDTM":"2022-02-13 11:00:51","AP01SDTM":"2020-05-03 05:02:53","AP01EDTM":"2021-02-13 05:00:51","AP02SDTM":"2021-02-13 05:00:51","AP02EDTM":"2022-02-13 11:00:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":652,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3501,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.28687,"AVALU":"U/L","BASE2":2.00165,"BASE":5.08827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.28522,"PCHG2":713.67259,"CHG":11.19861,"PCHG":220.08693,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-11-05 05:02:53","ADY":551,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-12-id-219","SUBJID":"id-219","SITEID":"JPN-12","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-12","INVNAM":"Dr. JPN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.39188,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 05:02:53","TRTEDTM":"2022-02-13 11:00:51","TRT01SDTM":"2020-05-03 05:02:53","TRT01EDTM":"2021-02-13 05:00:51","TRT02SDTM":"2021-02-13 05:00:51","TRT02EDTM":"2022-02-13 11:00:51","AP01SDTM":"2020-05-03 05:02:53","AP01EDTM":"2021-02-13 05:00:51","AP02SDTM":"2021-02-13 05:00:51","AP02EDTM":"2022-02-13 11:00:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":652,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2396,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.02692,"AVALU":"U/L","BASE2":2.00165,"BASE":5.08827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.02527,"PCHG2":450.89145,"CHG":5.93865,"PCHG":116.71266,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-01-23 05:02:53","ADY":630,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-12-id-219","SUBJID":"id-219","SITEID":"JPN-12","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-12","INVNAM":"Dr. JPN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.39188,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 05:02:53","TRTEDTM":"2022-02-13 11:00:51","TRT01SDTM":"2020-05-03 05:02:53","TRT01EDTM":"2021-02-13 05:00:51","TRT02SDTM":"2021-02-13 05:00:51","TRT02EDTM":"2022-02-13 11:00:51","AP01SDTM":"2020-05-03 05:02:53","AP01EDTM":"2021-02-13 05:00:51","AP02SDTM":"2021-02-13 05:00:51","AP02EDTM":"2022-02-13 11:00:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":652,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6213,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.25841,"AVALU":"mg/L","BASE2":10.25841,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-05-14 05:02:53","ADY":11,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-12-id-219","SUBJID":"id-219","SITEID":"JPN-12","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-12","INVNAM":"Dr. JPN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.39188,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 05:02:53","TRTEDTM":"2022-02-13 11:00:51","TRT01SDTM":"2020-05-03 05:02:53","TRT01EDTM":"2021-02-13 05:00:51","TRT02SDTM":"2021-02-13 05:00:51","TRT02EDTM":"2022-02-13 11:00:51","AP01SDTM":"2020-05-03 05:02:53","AP01EDTM":"2021-02-13 05:00:51","AP02SDTM":"2021-02-13 05:00:51","AP02EDTM":"2022-02-13 11:00:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":652,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1974,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.93469,"AVALU":"mg/L","BASE2":10.25841,"BASE":8.93469,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.32372,"PCHG2":-12.90376,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-05 05:02:53","ADY":247,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-12-id-219","SUBJID":"id-219","SITEID":"JPN-12","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-12","INVNAM":"Dr. JPN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.39188,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 05:02:53","TRTEDTM":"2022-02-13 11:00:51","TRT01SDTM":"2020-05-03 05:02:53","TRT01EDTM":"2021-02-13 05:00:51","TRT02SDTM":"2021-02-13 05:00:51","TRT02EDTM":"2022-02-13 11:00:51","AP01SDTM":"2020-05-03 05:02:53","AP01EDTM":"2021-02-13 05:00:51","AP02SDTM":"2021-02-13 05:00:51","AP02EDTM":"2022-02-13 11:00:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":652,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2650,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.36386,"AVALU":"mg/L","BASE2":10.25841,"BASE":8.93469,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10545,"PCHG2":1.0279,"CHG":1.42917,"PCHG":15.9957,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-02-24 05:02:53","ADY":297,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-12-id-219","SUBJID":"id-219","SITEID":"JPN-12","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-12","INVNAM":"Dr. JPN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.39188,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 05:02:53","TRTEDTM":"2022-02-13 11:00:51","TRT01SDTM":"2020-05-03 05:02:53","TRT01EDTM":"2021-02-13 05:00:51","TRT02SDTM":"2021-02-13 05:00:51","TRT02EDTM":"2022-02-13 11:00:51","AP01SDTM":"2020-05-03 05:02:53","AP01EDTM":"2021-02-13 05:00:51","AP02SDTM":"2021-02-13 05:00:51","AP02EDTM":"2022-02-13 11:00:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":652,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6362,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.31964,"AVALU":"mg/L","BASE2":10.25841,"BASE":8.93469,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06123,"PCHG2":0.59683,"CHG":1.38495,"PCHG":15.50077,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-08-29 05:02:53","ADY":483,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-12-id-219","SUBJID":"id-219","SITEID":"JPN-12","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-12","INVNAM":"Dr. JPN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.39188,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 05:02:53","TRTEDTM":"2022-02-13 11:00:51","TRT01SDTM":"2020-05-03 05:02:53","TRT01EDTM":"2021-02-13 05:00:51","TRT02SDTM":"2021-02-13 05:00:51","TRT02EDTM":"2022-02-13 11:00:51","AP01SDTM":"2020-05-03 05:02:53","AP01EDTM":"2021-02-13 05:00:51","AP02SDTM":"2021-02-13 05:00:51","AP02EDTM":"2022-02-13 11:00:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":652,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1710,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.3432,"AVALU":"mg/L","BASE2":10.25841,"BASE":8.93469,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.91521,"PCHG2":-18.66964,"CHG":-0.59149,"PCHG":-6.62013,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-07 05:02:53","ADY":492,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-12-id-219","SUBJID":"id-219","SITEID":"JPN-12","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-12","INVNAM":"Dr. JPN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.39188,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 05:02:53","TRTEDTM":"2022-02-13 11:00:51","TRT01SDTM":"2020-05-03 05:02:53","TRT01EDTM":"2021-02-13 05:00:51","TRT02SDTM":"2021-02-13 05:00:51","TRT02EDTM":"2022-02-13 11:00:51","AP01SDTM":"2020-05-03 05:02:53","AP01EDTM":"2021-02-13 05:00:51","AP02SDTM":"2021-02-13 05:00:51","AP02EDTM":"2022-02-13 11:00:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":652,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7911,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.23755,"AVALU":"mg/L","BASE2":10.25841,"BASE":8.93469,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.02086,"PCHG2":-9.95146,"CHG":0.30286,"PCHG":3.3897,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-05 05:02:53","ADY":551,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-12-id-219","SUBJID":"id-219","SITEID":"JPN-12","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-12","INVNAM":"Dr. JPN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.39188,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 05:02:53","TRTEDTM":"2022-02-13 11:00:51","TRT01SDTM":"2020-05-03 05:02:53","TRT01EDTM":"2021-02-13 05:00:51","TRT02SDTM":"2021-02-13 05:00:51","TRT02EDTM":"2022-02-13 11:00:51","AP01SDTM":"2020-05-03 05:02:53","AP01EDTM":"2021-02-13 05:00:51","AP02SDTM":"2021-02-13 05:00:51","AP02EDTM":"2022-02-13 11:00:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":652,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5979,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.45739,"AVALU":"mg/L","BASE2":10.25841,"BASE":8.93469,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.80102,"PCHG2":-7.80839,"CHG":0.5227,"PCHG":5.85028,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-23 05:02:53","ADY":630,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-12-id-219","SUBJID":"id-219","SITEID":"JPN-12","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-12","INVNAM":"Dr. JPN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.39188,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 05:02:53","TRTEDTM":"2022-02-13 11:00:51","TRT01SDTM":"2020-05-03 05:02:53","TRT01EDTM":"2021-02-13 05:00:51","TRT02SDTM":"2021-02-13 05:00:51","TRT02EDTM":"2022-02-13 11:00:51","AP01SDTM":"2020-05-03 05:02:53","AP01EDTM":"2021-02-13 05:00:51","AP02SDTM":"2021-02-13 05:00:51","AP02EDTM":"2022-02-13 11:00:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":652,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6999,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.08534,"AVALU":"g/L","BASE2":3.08534,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-05-14 05:02:53","ADY":11,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-12-id-219","SUBJID":"id-219","SITEID":"JPN-12","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-12","INVNAM":"Dr. JPN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.39188,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 05:02:53","TRTEDTM":"2022-02-13 11:00:51","TRT01SDTM":"2020-05-03 05:02:53","TRT01EDTM":"2021-02-13 05:00:51","TRT02SDTM":"2021-02-13 05:00:51","TRT02EDTM":"2022-02-13 11:00:51","AP01SDTM":"2020-05-03 05:02:53","AP01EDTM":"2021-02-13 05:00:51","AP02SDTM":"2021-02-13 05:00:51","AP02EDTM":"2022-02-13 11:00:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":652,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7430,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8602,"AVALU":"g/L","BASE2":3.08534,"BASE":2.8602,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.22514,"PCHG2":-7.29702,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-05 05:02:53","ADY":247,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-12-id-219","SUBJID":"id-219","SITEID":"JPN-12","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-12","INVNAM":"Dr. JPN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.39188,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 05:02:53","TRTEDTM":"2022-02-13 11:00:51","TRT01SDTM":"2020-05-03 05:02:53","TRT01EDTM":"2021-02-13 05:00:51","TRT02SDTM":"2021-02-13 05:00:51","TRT02EDTM":"2022-02-13 11:00:51","AP01SDTM":"2020-05-03 05:02:53","AP01EDTM":"2021-02-13 05:00:51","AP02SDTM":"2021-02-13 05:00:51","AP02EDTM":"2022-02-13 11:00:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":652,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4208,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97374,"AVALU":"g/L","BASE2":3.08534,"BASE":2.8602,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1116,"PCHG2":-3.61718,"CHG":0.11354,"PCHG":3.9695,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-24 05:02:53","ADY":297,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-12-id-219","SUBJID":"id-219","SITEID":"JPN-12","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-12","INVNAM":"Dr. JPN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.39188,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 05:02:53","TRTEDTM":"2022-02-13 11:00:51","TRT01SDTM":"2020-05-03 05:02:53","TRT01EDTM":"2021-02-13 05:00:51","TRT02SDTM":"2021-02-13 05:00:51","TRT02EDTM":"2022-02-13 11:00:51","AP01SDTM":"2020-05-03 05:02:53","AP01EDTM":"2021-02-13 05:00:51","AP02SDTM":"2021-02-13 05:00:51","AP02EDTM":"2022-02-13 11:00:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":652,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6075,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91392,"AVALU":"g/L","BASE2":3.08534,"BASE":2.8602,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17142,"PCHG2":-5.55609,"CHG":0.05371,"PCHG":1.87796,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-29 05:02:53","ADY":483,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-12-id-219","SUBJID":"id-219","SITEID":"JPN-12","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-12","INVNAM":"Dr. JPN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.39188,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 05:02:53","TRTEDTM":"2022-02-13 11:00:51","TRT01SDTM":"2020-05-03 05:02:53","TRT01EDTM":"2021-02-13 05:00:51","TRT02SDTM":"2021-02-13 05:00:51","TRT02EDTM":"2022-02-13 11:00:51","AP01SDTM":"2020-05-03 05:02:53","AP01EDTM":"2021-02-13 05:00:51","AP02SDTM":"2021-02-13 05:00:51","AP02EDTM":"2022-02-13 11:00:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":652,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7215,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00566,"AVALU":"g/L","BASE2":3.08534,"BASE":2.8602,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07968,"PCHG2":-2.58238,"CHG":0.14546,"PCHG":5.08574,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-09-07 05:02:53","ADY":492,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-12-id-219","SUBJID":"id-219","SITEID":"JPN-12","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-12","INVNAM":"Dr. JPN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.39188,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 05:02:53","TRTEDTM":"2022-02-13 11:00:51","TRT01SDTM":"2020-05-03 05:02:53","TRT01EDTM":"2021-02-13 05:00:51","TRT02SDTM":"2021-02-13 05:00:51","TRT02EDTM":"2022-02-13 11:00:51","AP01SDTM":"2020-05-03 05:02:53","AP01EDTM":"2021-02-13 05:00:51","AP02SDTM":"2021-02-13 05:00:51","AP02EDTM":"2022-02-13 11:00:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":652,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7836,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8555,"AVALU":"g/L","BASE2":3.08534,"BASE":2.8602,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.22984,"PCHG2":-7.44934,"CHG":-0.0047,"PCHG":-0.16431,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-05 05:02:53","ADY":551,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-12-id-219","SUBJID":"id-219","SITEID":"JPN-12","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-12","INVNAM":"Dr. JPN-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.39188,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-30","TRTSDTM":"2020-05-03 05:02:53","TRTEDTM":"2022-02-13 11:00:51","TRT01SDTM":"2020-05-03 05:02:53","TRT01EDTM":"2021-02-13 05:00:51","TRT02SDTM":"2021-02-13 05:00:51","TRT02EDTM":"2022-02-13 11:00:51","AP01SDTM":"2020-05-03 05:02:53","AP01EDTM":"2021-02-13 05:00:51","AP02SDTM":"2021-02-13 05:00:51","AP02EDTM":"2022-02-13 11:00:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":652,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-12","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3482,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0675,"AVALU":"g/L","BASE2":3.08534,"BASE":2.8602,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01784,"PCHG2":-0.57816,"CHG":0.2073,"PCHG":7.24772,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-01-23 05:02:53","ADY":630,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-14-id-194","SUBJID":"id-194","SITEID":"JPN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-14","INVNAM":"Dr. JPN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.44686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-31","TRTSDTM":"2019-11-01 00:14:23","TRT01SDTM":"2019-11-01 00:14:23","AP01SDTM":"2019-11-01 00:14:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8035,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.11106,"AVALU":"U/L","BASE2":12.11106,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-03 00:14:23","ADY":63,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-14-id-194","SUBJID":"id-194","SITEID":"JPN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-14","INVNAM":"Dr. JPN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.44686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-31","TRTSDTM":"2019-11-01 00:14:23","TRT01SDTM":"2019-11-01 00:14:23","AP01SDTM":"2019-11-01 00:14:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5416,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.74069,"AVALU":"U/L","BASE2":12.11106,"BASE":9.74069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.37036,"PCHG2":-19.57189,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-01 00:14:23","ADY":213,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-14-id-194","SUBJID":"id-194","SITEID":"JPN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-14","INVNAM":"Dr. JPN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.44686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-31","TRTSDTM":"2019-11-01 00:14:23","TRT01SDTM":"2019-11-01 00:14:23","AP01SDTM":"2019-11-01 00:14:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4076,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.11875,"AVALU":"U/L","BASE2":12.11106,"BASE":9.74069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.99231,"PCHG2":-8.19342,"CHG":1.37805,"PCHG":14.14738,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-02 00:14:23","ADY":244,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-14-id-194","SUBJID":"id-194","SITEID":"JPN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-14","INVNAM":"Dr. JPN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.44686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-31","TRTSDTM":"2019-11-01 00:14:23","TRT01SDTM":"2019-11-01 00:14:23","AP01SDTM":"2019-11-01 00:14:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":965,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.02363,"AVALU":"U/L","BASE2":12.11106,"BASE":9.74069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.91258,"PCHG2":65.33351,"CHG":10.28294,"PCHG":105.56681,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-01 00:14:23","ADY":396,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-14-id-194","SUBJID":"id-194","SITEID":"JPN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-14","INVNAM":"Dr. JPN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.44686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-31","TRTSDTM":"2019-11-01 00:14:23","TRT01SDTM":"2019-11-01 00:14:23","AP01SDTM":"2019-11-01 00:14:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8195,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.67624,"AVALU":"U/L","BASE2":12.11106,"BASE":9.74069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.56519,"PCHG2":29.43747,"CHG":5.93555,"PCHG":60.93561,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-11 00:14:23","ADY":437,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-14-id-194","SUBJID":"id-194","SITEID":"JPN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-14","INVNAM":"Dr. JPN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.44686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-31","TRTSDTM":"2019-11-01 00:14:23","TRT01SDTM":"2019-11-01 00:14:23","AP01SDTM":"2019-11-01 00:14:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4917,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.26823,"AVALU":"U/L","BASE2":12.11106,"BASE":9.74069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.15718,"PCHG2":100.38083,"CHG":14.52754,"PCHG":149.14277,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-07 00:14:23","ADY":584,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-14-id-194","SUBJID":"id-194","SITEID":"JPN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-14","INVNAM":"Dr. JPN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.44686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-31","TRTSDTM":"2019-11-01 00:14:23","TRT01SDTM":"2019-11-01 00:14:23","AP01SDTM":"2019-11-01 00:14:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2704,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.13452,"AVALU":"U/L","BASE2":12.11106,"BASE":9.74069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.02347,"PCHG2":99.27678,"CHG":14.39383,"PCHG":147.77005,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-31 00:14:23","ADY":669,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-14-id-194","SUBJID":"id-194","SITEID":"JPN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-14","INVNAM":"Dr. JPN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.44686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-31","TRTSDTM":"2019-11-01 00:14:23","TRT01SDTM":"2019-11-01 00:14:23","AP01SDTM":"2019-11-01 00:14:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3968,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.21674,"AVALU":"mg/L","BASE2":8.21674,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-03 00:14:23","ADY":63,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-14-id-194","SUBJID":"id-194","SITEID":"JPN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-14","INVNAM":"Dr. JPN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.44686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-31","TRTSDTM":"2019-11-01 00:14:23","TRT01SDTM":"2019-11-01 00:14:23","AP01SDTM":"2019-11-01 00:14:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8123,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.80335,"AVALU":"mg/L","BASE2":8.21674,"BASE":8.80335,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.58661,"PCHG2":7.13919,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-01 00:14:23","ADY":213,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-14-id-194","SUBJID":"id-194","SITEID":"JPN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-14","INVNAM":"Dr. JPN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.44686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-31","TRTSDTM":"2019-11-01 00:14:23","TRT01SDTM":"2019-11-01 00:14:23","AP01SDTM":"2019-11-01 00:14:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3143,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.08421,"AVALU":"mg/L","BASE2":8.21674,"BASE":8.80335,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.86747,"PCHG2":10.5574,"CHG":0.28087,"PCHG":3.19044,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-02 00:14:23","ADY":244,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-14-id-194","SUBJID":"id-194","SITEID":"JPN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-14","INVNAM":"Dr. JPN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.44686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-31","TRTSDTM":"2019-11-01 00:14:23","TRT01SDTM":"2019-11-01 00:14:23","AP01SDTM":"2019-11-01 00:14:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1010,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.59191,"AVALU":"mg/L","BASE2":8.21674,"BASE":8.80335,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.37517,"PCHG2":4.56589,"CHG":-0.21144,"PCHG":-2.40182,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-01 00:14:23","ADY":396,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-14-id-194","SUBJID":"id-194","SITEID":"JPN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-14","INVNAM":"Dr. JPN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.44686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-31","TRTSDTM":"2019-11-01 00:14:23","TRT01SDTM":"2019-11-01 00:14:23","AP01SDTM":"2019-11-01 00:14:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":160,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.30731,"AVALU":"mg/L","BASE2":8.21674,"BASE":8.80335,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.09057,"PCHG2":13.27256,"CHG":0.50396,"PCHG":5.72468,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-11 00:14:23","ADY":437,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-14-id-194","SUBJID":"id-194","SITEID":"JPN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-14","INVNAM":"Dr. JPN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.44686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-31","TRTSDTM":"2019-11-01 00:14:23","TRT01SDTM":"2019-11-01 00:14:23","AP01SDTM":"2019-11-01 00:14:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4394,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.37364,"AVALU":"mg/L","BASE2":8.21674,"BASE":8.80335,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1569,"PCHG2":1.9095,"CHG":-0.42971,"PCHG":-4.88121,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-07 00:14:23","ADY":584,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-14-id-194","SUBJID":"id-194","SITEID":"JPN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-14","INVNAM":"Dr. JPN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.44686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-31","TRTSDTM":"2019-11-01 00:14:23","TRT01SDTM":"2019-11-01 00:14:23","AP01SDTM":"2019-11-01 00:14:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":498,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.89112,"AVALU":"mg/L","BASE2":8.21674,"BASE":8.80335,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.67439,"PCHG2":20.37775,"CHG":1.08778,"PCHG":12.35641,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-31 00:14:23","ADY":669,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-14-id-194","SUBJID":"id-194","SITEID":"JPN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-14","INVNAM":"Dr. JPN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.44686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-31","TRTSDTM":"2019-11-01 00:14:23","TRT01SDTM":"2019-11-01 00:14:23","AP01SDTM":"2019-11-01 00:14:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5956,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.71707,"AVALU":"g/L","BASE2":2.71707,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"4","ADTM":"2020-01-03 00:14:23","ADY":63,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-14-id-194","SUBJID":"id-194","SITEID":"JPN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-14","INVNAM":"Dr. JPN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.44686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-31","TRTSDTM":"2019-11-01 00:14:23","TRT01SDTM":"2019-11-01 00:14:23","AP01SDTM":"2019-11-01 00:14:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4294,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03818,"AVALU":"g/L","BASE2":2.71707,"BASE":3.03818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.3211,"PCHG2":11.818,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"4","BTOXGR":"4","ADTM":"2020-06-01 00:14:23","ADY":213,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-14-id-194","SUBJID":"id-194","SITEID":"JPN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-14","INVNAM":"Dr. JPN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.44686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-31","TRTSDTM":"2019-11-01 00:14:23","TRT01SDTM":"2019-11-01 00:14:23","AP01SDTM":"2019-11-01 00:14:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2323,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76412,"AVALU":"g/L","BASE2":2.71707,"BASE":3.03818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04704,"PCHG2":1.73139,"CHG":-0.27406,"PCHG":-9.02056,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2020-07-02 00:14:23","ADY":244,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-14-id-194","SUBJID":"id-194","SITEID":"JPN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-14","INVNAM":"Dr. JPN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.44686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-31","TRTSDTM":"2019-11-01 00:14:23","TRT01SDTM":"2019-11-01 00:14:23","AP01SDTM":"2019-11-01 00:14:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4406,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.61961,"AVALU":"g/L","BASE2":2.71707,"BASE":3.03818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09746,"PCHG2":-3.58698,"CHG":-0.41856,"PCHG":-13.77684,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2020-12-01 00:14:23","ADY":396,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-14-id-194","SUBJID":"id-194","SITEID":"JPN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-14","INVNAM":"Dr. JPN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.44686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-31","TRTSDTM":"2019-11-01 00:14:23","TRT01SDTM":"2019-11-01 00:14:23","AP01SDTM":"2019-11-01 00:14:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1553,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89211,"AVALU":"g/L","BASE2":2.71707,"BASE":3.03818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17504,"PCHG2":6.44215,"CHG":-0.14607,"PCHG":-4.80768,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2021-01-11 00:14:23","ADY":437,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-14-id-194","SUBJID":"id-194","SITEID":"JPN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-14","INVNAM":"Dr. JPN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.44686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-31","TRTSDTM":"2019-11-01 00:14:23","TRT01SDTM":"2019-11-01 00:14:23","AP01SDTM":"2019-11-01 00:14:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6360,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81825,"AVALU":"g/L","BASE2":2.71707,"BASE":3.03818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10117,"PCHG2":3.72362,"CHG":-0.21993,"PCHG":-7.23889,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2021-06-07 00:14:23","ADY":584,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-14-id-194","SUBJID":"id-194","SITEID":"JPN-14","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-14","INVNAM":"Dr. JPN-14 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.44686,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-31","TRTSDTM":"2019-11-01 00:14:23","TRT01SDTM":"2019-11-01 00:14:23","AP01SDTM":"2019-11-01 00:14:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7608,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8637,"AVALU":"g/L","BASE2":2.71707,"BASE":3.03818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14663,"PCHG2":5.39645,"CHG":-0.17448,"PCHG":-5.74286,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2021-08-31 00:14:23","ADY":669,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-250","SUBJID":"id-250","SITEID":"JPN-17","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.45958,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-17 09:49:22","TRTEDTM":"2022-02-17 20:00:41","TRT01SDTM":"2020-02-17 09:49:22","TRT01EDTM":"2021-02-17 14:00:41","TRT02SDTM":"2021-02-17 14:00:41","TRT02EDTM":"2022-02-17 20:00:41","AP01SDTM":"2020-02-17 09:49:22","AP01EDTM":"2021-02-17 14:00:41","AP02SDTM":"2021-02-17 14:00:41","AP02EDTM":"2022-02-17 20:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":732,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":13,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":743,"ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2212,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.18924,"AVALU":"U/L","BASE2":14.18924,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-21 09:49:22","ADY":64,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-250","SUBJID":"id-250","SITEID":"JPN-17","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.45958,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-17 09:49:22","TRTEDTM":"2022-02-17 20:00:41","TRT01SDTM":"2020-02-17 09:49:22","TRT01EDTM":"2021-02-17 14:00:41","TRT02SDTM":"2021-02-17 14:00:41","TRT02EDTM":"2022-02-17 20:00:41","AP01SDTM":"2020-02-17 09:49:22","AP01EDTM":"2021-02-17 14:00:41","AP02SDTM":"2021-02-17 14:00:41","AP02EDTM":"2022-02-17 20:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":732,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":13,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":743,"ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7435,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.3696,"AVALU":"U/L","BASE2":14.18924,"BASE":25.3696,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":11.18036,"PCHG2":78.79462,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-26 09:49:22","ADY":313,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-250","SUBJID":"id-250","SITEID":"JPN-17","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.45958,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-17 09:49:22","TRTEDTM":"2022-02-17 20:00:41","TRT01SDTM":"2020-02-17 09:49:22","TRT01EDTM":"2021-02-17 14:00:41","TRT02SDTM":"2021-02-17 14:00:41","TRT02EDTM":"2022-02-17 20:00:41","AP01SDTM":"2020-02-17 09:49:22","AP01EDTM":"2021-02-17 14:00:41","AP02SDTM":"2021-02-17 14:00:41","AP02EDTM":"2022-02-17 20:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":732,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":13,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":743,"ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7586,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.88641,"AVALU":"U/L","BASE2":14.18924,"BASE":25.3696,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.69717,"PCHG2":26.05613,"CHG":-7.48319,"PCHG":-29.49669,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-04 09:49:22","ADY":353,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-250","SUBJID":"id-250","SITEID":"JPN-17","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.45958,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-17 09:49:22","TRTEDTM":"2022-02-17 20:00:41","TRT01SDTM":"2020-02-17 09:49:22","TRT01EDTM":"2021-02-17 14:00:41","TRT02SDTM":"2021-02-17 14:00:41","TRT02EDTM":"2022-02-17 20:00:41","AP01SDTM":"2020-02-17 09:49:22","AP01EDTM":"2021-02-17 14:00:41","AP02SDTM":"2021-02-17 14:00:41","AP02EDTM":"2022-02-17 20:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":732,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":13,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":743,"ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1398,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.11854,"AVALU":"U/L","BASE2":14.18924,"BASE":25.3696,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.0707,"PCHG2":-78.02182,"CHG":-22.25106,"PCHG":-87.70758,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-02-10 09:49:22","ADY":359,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-250","SUBJID":"id-250","SITEID":"JPN-17","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.45958,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-17 09:49:22","TRTEDTM":"2022-02-17 20:00:41","TRT01SDTM":"2020-02-17 09:49:22","TRT01EDTM":"2021-02-17 14:00:41","TRT02SDTM":"2021-02-17 14:00:41","TRT02EDTM":"2022-02-17 20:00:41","AP01SDTM":"2020-02-17 09:49:22","AP01EDTM":"2021-02-17 14:00:41","AP02SDTM":"2021-02-17 14:00:41","AP02EDTM":"2022-02-17 20:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":732,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":13,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":743,"ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7941,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.7158,"AVALU":"U/L","BASE2":14.18924,"BASE":25.3696,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.52656,"PCHG2":38.94897,"CHG":-5.65379,"PCHG":-22.28571,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-19 09:49:22","ADY":396,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-250","SUBJID":"id-250","SITEID":"JPN-17","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.45958,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-17 09:49:22","TRTEDTM":"2022-02-17 20:00:41","TRT01SDTM":"2020-02-17 09:49:22","TRT01EDTM":"2021-02-17 14:00:41","TRT02SDTM":"2021-02-17 14:00:41","TRT02EDTM":"2022-02-17 20:00:41","AP01SDTM":"2020-02-17 09:49:22","AP01EDTM":"2021-02-17 14:00:41","AP02SDTM":"2021-02-17 14:00:41","AP02EDTM":"2022-02-17 20:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":732,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":13,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":743,"ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2160,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.36172,"AVALU":"U/L","BASE2":14.18924,"BASE":25.3696,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.82752,"PCHG2":-5.832,"CHG":-12.00787,"PCHG":-47.33175,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-16 09:49:22","ADY":485,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-250","SUBJID":"id-250","SITEID":"JPN-17","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.45958,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-17 09:49:22","TRTEDTM":"2022-02-17 20:00:41","TRT01SDTM":"2020-02-17 09:49:22","TRT01EDTM":"2021-02-17 14:00:41","TRT02SDTM":"2021-02-17 14:00:41","TRT02EDTM":"2022-02-17 20:00:41","AP01SDTM":"2020-02-17 09:49:22","AP01EDTM":"2021-02-17 14:00:41","AP02SDTM":"2021-02-17 14:00:41","AP02EDTM":"2022-02-17 20:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":732,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":13,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":743,"ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5644,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.09506,"AVALU":"U/L","BASE2":14.18924,"BASE":25.3696,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.90582,"PCHG2":69.81223,"CHG":-1.27453,"PCHG":-5.02386,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-17 09:49:22","ADY":516,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-250","SUBJID":"id-250","SITEID":"JPN-17","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.45958,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-17 09:49:22","TRTEDTM":"2022-02-17 20:00:41","TRT01SDTM":"2020-02-17 09:49:22","TRT01EDTM":"2021-02-17 14:00:41","TRT02SDTM":"2021-02-17 14:00:41","TRT02EDTM":"2022-02-17 20:00:41","AP01SDTM":"2020-02-17 09:49:22","AP01EDTM":"2021-02-17 14:00:41","AP02SDTM":"2021-02-17 14:00:41","AP02EDTM":"2022-02-17 20:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":732,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":13,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":743,"ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1923,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.55225,"AVALU":"mg/L","BASE2":11.55225,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"1","ADTM":"2020-04-21 09:49:22","ADY":64,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-250","SUBJID":"id-250","SITEID":"JPN-17","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.45958,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-17 09:49:22","TRTEDTM":"2022-02-17 20:00:41","TRT01SDTM":"2020-02-17 09:49:22","TRT01EDTM":"2021-02-17 14:00:41","TRT02SDTM":"2021-02-17 14:00:41","TRT02EDTM":"2022-02-17 20:00:41","AP01SDTM":"2020-02-17 09:49:22","AP01EDTM":"2021-02-17 14:00:41","AP02SDTM":"2021-02-17 14:00:41","AP02EDTM":"2022-02-17 20:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":732,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":13,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":743,"ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4330,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.60857,"AVALU":"mg/L","BASE2":11.55225,"BASE":10.60857,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.94368,"PCHG2":-8.16881,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-12-26 09:49:22","ADY":313,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-250","SUBJID":"id-250","SITEID":"JPN-17","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.45958,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-17 09:49:22","TRTEDTM":"2022-02-17 20:00:41","TRT01SDTM":"2020-02-17 09:49:22","TRT01EDTM":"2021-02-17 14:00:41","TRT02SDTM":"2021-02-17 14:00:41","TRT02EDTM":"2022-02-17 20:00:41","AP01SDTM":"2020-02-17 09:49:22","AP01EDTM":"2021-02-17 14:00:41","AP02SDTM":"2021-02-17 14:00:41","AP02EDTM":"2022-02-17 20:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":732,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":13,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":743,"ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":776,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.16439,"AVALU":"mg/L","BASE2":11.55225,"BASE":10.60857,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.38786,"PCHG2":-29.3264,"CHG":-2.44418,"PCHG":-23.03966,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-02-04 09:49:22","ADY":353,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-250","SUBJID":"id-250","SITEID":"JPN-17","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.45958,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-17 09:49:22","TRTEDTM":"2022-02-17 20:00:41","TRT01SDTM":"2020-02-17 09:49:22","TRT01EDTM":"2021-02-17 14:00:41","TRT02SDTM":"2021-02-17 14:00:41","TRT02EDTM":"2022-02-17 20:00:41","AP01SDTM":"2020-02-17 09:49:22","AP01EDTM":"2021-02-17 14:00:41","AP02SDTM":"2021-02-17 14:00:41","AP02EDTM":"2022-02-17 20:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":732,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":13,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":743,"ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4302,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.50067,"AVALU":"mg/L","BASE2":11.55225,"BASE":10.60857,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.05158,"PCHG2":-9.10283,"CHG":-0.1079,"PCHG":-1.01711,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"1","ADTM":"2021-02-10 09:49:22","ADY":359,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-250","SUBJID":"id-250","SITEID":"JPN-17","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.45958,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-17 09:49:22","TRTEDTM":"2022-02-17 20:00:41","TRT01SDTM":"2020-02-17 09:49:22","TRT01EDTM":"2021-02-17 14:00:41","TRT02SDTM":"2021-02-17 14:00:41","TRT02EDTM":"2022-02-17 20:00:41","AP01SDTM":"2020-02-17 09:49:22","AP01EDTM":"2021-02-17 14:00:41","AP02SDTM":"2021-02-17 14:00:41","AP02EDTM":"2022-02-17 20:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":732,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":13,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":743,"ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7419,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.93286,"AVALU":"mg/L","BASE2":11.55225,"BASE":10.60857,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.61939,"PCHG2":-14.01795,"CHG":-0.67571,"PCHG":-6.36945,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-03-19 09:49:22","ADY":396,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-250","SUBJID":"id-250","SITEID":"JPN-17","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.45958,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-17 09:49:22","TRTEDTM":"2022-02-17 20:00:41","TRT01SDTM":"2020-02-17 09:49:22","TRT01EDTM":"2021-02-17 14:00:41","TRT02SDTM":"2021-02-17 14:00:41","TRT02EDTM":"2022-02-17 20:00:41","AP01SDTM":"2020-02-17 09:49:22","AP01EDTM":"2021-02-17 14:00:41","AP02SDTM":"2021-02-17 14:00:41","AP02EDTM":"2022-02-17 20:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":732,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":13,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":743,"ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1586,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.54791,"AVALU":"mg/L","BASE2":11.55225,"BASE":10.60857,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.00435,"PCHG2":-34.6629,"CHG":-3.06066,"PCHG":-28.85086,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-3","BTOXGR":"1","ADTM":"2021-06-16 09:49:22","ADY":485,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-250","SUBJID":"id-250","SITEID":"JPN-17","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.45958,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-17 09:49:22","TRTEDTM":"2022-02-17 20:00:41","TRT01SDTM":"2020-02-17 09:49:22","TRT01EDTM":"2021-02-17 14:00:41","TRT02SDTM":"2021-02-17 14:00:41","TRT02EDTM":"2022-02-17 20:00:41","AP01SDTM":"2020-02-17 09:49:22","AP01EDTM":"2021-02-17 14:00:41","AP02SDTM":"2021-02-17 14:00:41","AP02EDTM":"2022-02-17 20:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":732,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":13,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":743,"ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3714,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.52456,"AVALU":"mg/L","BASE2":11.55225,"BASE":10.60857,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.02769,"PCHG2":-17.55235,"CHG":-1.08401,"PCHG":-10.21825,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-07-17 09:49:22","ADY":516,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-250","SUBJID":"id-250","SITEID":"JPN-17","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.45958,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-17 09:49:22","TRTEDTM":"2022-02-17 20:00:41","TRT01SDTM":"2020-02-17 09:49:22","TRT01EDTM":"2021-02-17 14:00:41","TRT02SDTM":"2021-02-17 14:00:41","TRT02EDTM":"2022-02-17 20:00:41","AP01SDTM":"2020-02-17 09:49:22","AP01EDTM":"2021-02-17 14:00:41","AP02SDTM":"2021-02-17 14:00:41","AP02EDTM":"2022-02-17 20:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":732,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":13,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":743,"ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8284,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92524,"AVALU":"g/L","BASE2":2.92524,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-21 09:49:22","ADY":64,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-250","SUBJID":"id-250","SITEID":"JPN-17","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.45958,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-17 09:49:22","TRTEDTM":"2022-02-17 20:00:41","TRT01SDTM":"2020-02-17 09:49:22","TRT01EDTM":"2021-02-17 14:00:41","TRT02SDTM":"2021-02-17 14:00:41","TRT02EDTM":"2022-02-17 20:00:41","AP01SDTM":"2020-02-17 09:49:22","AP01EDTM":"2021-02-17 14:00:41","AP02SDTM":"2021-02-17 14:00:41","AP02EDTM":"2022-02-17 20:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":732,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":13,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":743,"ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5230,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80171,"AVALU":"g/L","BASE2":2.92524,"BASE":2.80171,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.12352,"PCHG2":-4.22266,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-26 09:49:22","ADY":313,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-250","SUBJID":"id-250","SITEID":"JPN-17","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.45958,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-17 09:49:22","TRTEDTM":"2022-02-17 20:00:41","TRT01SDTM":"2020-02-17 09:49:22","TRT01EDTM":"2021-02-17 14:00:41","TRT02SDTM":"2021-02-17 14:00:41","TRT02EDTM":"2022-02-17 20:00:41","AP01SDTM":"2020-02-17 09:49:22","AP01EDTM":"2021-02-17 14:00:41","AP02SDTM":"2021-02-17 14:00:41","AP02EDTM":"2022-02-17 20:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":732,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":13,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":743,"ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":781,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8962,"AVALU":"g/L","BASE2":2.92524,"BASE":2.80171,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02904,"PCHG2":-0.99273,"CHG":0.09448,"PCHG":3.37233,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-04 09:49:22","ADY":353,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-250","SUBJID":"id-250","SITEID":"JPN-17","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.45958,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-17 09:49:22","TRTEDTM":"2022-02-17 20:00:41","TRT01SDTM":"2020-02-17 09:49:22","TRT01EDTM":"2021-02-17 14:00:41","TRT02SDTM":"2021-02-17 14:00:41","TRT02EDTM":"2022-02-17 20:00:41","AP01SDTM":"2020-02-17 09:49:22","AP01EDTM":"2021-02-17 14:00:41","AP02SDTM":"2021-02-17 14:00:41","AP02EDTM":"2022-02-17 20:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":732,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":13,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":743,"ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7216,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94719,"AVALU":"g/L","BASE2":2.92524,"BASE":2.80171,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02196,"PCHG2":0.75062,"CHG":0.14548,"PCHG":5.19254,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-10 09:49:22","ADY":359,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-250","SUBJID":"id-250","SITEID":"JPN-17","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.45958,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-17 09:49:22","TRTEDTM":"2022-02-17 20:00:41","TRT01SDTM":"2020-02-17 09:49:22","TRT01EDTM":"2021-02-17 14:00:41","TRT02SDTM":"2021-02-17 14:00:41","TRT02EDTM":"2022-02-17 20:00:41","AP01SDTM":"2020-02-17 09:49:22","AP01EDTM":"2021-02-17 14:00:41","AP02SDTM":"2021-02-17 14:00:41","AP02EDTM":"2022-02-17 20:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":732,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":13,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":743,"ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1434,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88529,"AVALU":"g/L","BASE2":2.92524,"BASE":2.80171,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03994,"PCHG2":-1.3655,"CHG":0.08358,"PCHG":2.98313,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-19 09:49:22","ADY":396,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-250","SUBJID":"id-250","SITEID":"JPN-17","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.45958,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-17 09:49:22","TRTEDTM":"2022-02-17 20:00:41","TRT01SDTM":"2020-02-17 09:49:22","TRT01EDTM":"2021-02-17 14:00:41","TRT02SDTM":"2021-02-17 14:00:41","TRT02EDTM":"2022-02-17 20:00:41","AP01SDTM":"2020-02-17 09:49:22","AP01EDTM":"2021-02-17 14:00:41","AP02SDTM":"2021-02-17 14:00:41","AP02EDTM":"2022-02-17 20:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":732,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":13,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":743,"ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2086,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94609,"AVALU":"g/L","BASE2":2.92524,"BASE":2.80171,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02085,"PCHG2":0.7129,"CHG":0.14438,"PCHG":5.15316,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-16 09:49:22","ADY":485,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-250","SUBJID":"id-250","SITEID":"JPN-17","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":5.45958,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-17","TRTSDTM":"2020-02-17 09:49:22","TRTEDTM":"2022-02-17 20:00:41","TRT01SDTM":"2020-02-17 09:49:22","TRT01EDTM":"2021-02-17 14:00:41","TRT02SDTM":"2021-02-17 14:00:41","TRT02EDTM":"2022-02-17 20:00:41","AP01SDTM":"2020-02-17 09:49:22","AP01EDTM":"2021-02-17 14:00:41","AP02SDTM":"2021-02-17 14:00:41","AP02EDTM":"2022-02-17 20:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":732,"DCSREAS":"DEATH","DTHDT":"2022-03-02","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":13,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-02","DTHADY":743,"ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8030,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83428,"AVALU":"g/L","BASE2":2.92524,"BASE":2.80171,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09095,"PCHG2":-3.10923,"CHG":0.03257,"PCHG":1.16251,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-17 09:49:22","ADY":516,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-393","SUBJID":"id-393","SITEID":"JPN-17","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65965,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-07","TRTSDTM":"2020-06-08 23:44:46","TRTEDTM":"2022-02-12 07:11:49","TRT01SDTM":"2020-06-08 23:44:46","TRT01EDTM":"2021-02-12 01:11:49","TRT02SDTM":"2021-02-12 01:11:49","TRT02EDTM":"2022-02-12 07:11:49","AP01SDTM":"2020-06-08 23:44:46","AP01EDTM":"2021-02-12 01:11:49","AP02SDTM":"2021-02-12 01:11:49","AP02EDTM":"2022-02-12 07:11:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":614,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":652,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5877,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.70055,"AVALU":"U/L","BASE2":20.70055,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-27 23:44:46","ADY":19,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-393","SUBJID":"id-393","SITEID":"JPN-17","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65965,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-07","TRTSDTM":"2020-06-08 23:44:46","TRTEDTM":"2022-02-12 07:11:49","TRT01SDTM":"2020-06-08 23:44:46","TRT01EDTM":"2021-02-12 01:11:49","TRT02SDTM":"2021-02-12 01:11:49","TRT02EDTM":"2022-02-12 07:11:49","AP01SDTM":"2020-06-08 23:44:46","AP01EDTM":"2021-02-12 01:11:49","AP02SDTM":"2021-02-12 01:11:49","AP02EDTM":"2022-02-12 07:11:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":614,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":652,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4032,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":36.70284,"AVALU":"U/L","BASE2":20.70055,"BASE":36.70284,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":16.00229,"PCHG2":77.30369,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-23 23:44:46","ADY":45,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-393","SUBJID":"id-393","SITEID":"JPN-17","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65965,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-07","TRTSDTM":"2020-06-08 23:44:46","TRTEDTM":"2022-02-12 07:11:49","TRT01SDTM":"2020-06-08 23:44:46","TRT01EDTM":"2021-02-12 01:11:49","TRT02SDTM":"2021-02-12 01:11:49","TRT02EDTM":"2022-02-12 07:11:49","AP01SDTM":"2020-06-08 23:44:46","AP01EDTM":"2021-02-12 01:11:49","AP02SDTM":"2021-02-12 01:11:49","AP02EDTM":"2022-02-12 07:11:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":614,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":652,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3891,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.77825,"AVALU":"U/L","BASE2":20.70055,"BASE":36.70284,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.9223,"PCHG2":-43.10174,"CHG":-24.92459,"PCHG":-67.90915,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-07 23:44:46","ADY":182,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-393","SUBJID":"id-393","SITEID":"JPN-17","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65965,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-07","TRTSDTM":"2020-06-08 23:44:46","TRTEDTM":"2022-02-12 07:11:49","TRT01SDTM":"2020-06-08 23:44:46","TRT01EDTM":"2021-02-12 01:11:49","TRT02SDTM":"2021-02-12 01:11:49","TRT02EDTM":"2022-02-12 07:11:49","AP01SDTM":"2020-06-08 23:44:46","AP01EDTM":"2021-02-12 01:11:49","AP02SDTM":"2021-02-12 01:11:49","AP02EDTM":"2022-02-12 07:11:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":614,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":652,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2984,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.32785,"AVALU":"U/L","BASE2":20.70055,"BASE":36.70284,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.3727,"PCHG2":-45.27755,"CHG":-25.37499,"PCHG":-69.13632,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-05 23:44:46","ADY":211,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-393","SUBJID":"id-393","SITEID":"JPN-17","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65965,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-07","TRTSDTM":"2020-06-08 23:44:46","TRTEDTM":"2022-02-12 07:11:49","TRT01SDTM":"2020-06-08 23:44:46","TRT01EDTM":"2021-02-12 01:11:49","TRT02SDTM":"2021-02-12 01:11:49","TRT02EDTM":"2022-02-12 07:11:49","AP01SDTM":"2020-06-08 23:44:46","AP01EDTM":"2021-02-12 01:11:49","AP02SDTM":"2021-02-12 01:11:49","AP02EDTM":"2022-02-12 07:11:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":614,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":652,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3004,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.39456,"AVALU":"U/L","BASE2":20.70055,"BASE":36.70284,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.69401,"PCHG2":3.35262,"CHG":-15.30828,"PCHG":-41.7087,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-12 23:44:46","ADY":218,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-393","SUBJID":"id-393","SITEID":"JPN-17","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65965,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-07","TRTSDTM":"2020-06-08 23:44:46","TRTEDTM":"2022-02-12 07:11:49","TRT01SDTM":"2020-06-08 23:44:46","TRT01EDTM":"2021-02-12 01:11:49","TRT02SDTM":"2021-02-12 01:11:49","TRT02EDTM":"2022-02-12 07:11:49","AP01SDTM":"2020-06-08 23:44:46","AP01EDTM":"2021-02-12 01:11:49","AP02SDTM":"2021-02-12 01:11:49","AP02EDTM":"2022-02-12 07:11:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":614,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":652,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3825,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.87767,"AVALU":"U/L","BASE2":20.70055,"BASE":36.70284,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.17712,"PCHG2":39.50193,"CHG":-7.82517,"PCHG":-21.32034,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-11 23:44:46","ADY":368,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-393","SUBJID":"id-393","SITEID":"JPN-17","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65965,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-07","TRTSDTM":"2020-06-08 23:44:46","TRTEDTM":"2022-02-12 07:11:49","TRT01SDTM":"2020-06-08 23:44:46","TRT01EDTM":"2021-02-12 01:11:49","TRT02SDTM":"2021-02-12 01:11:49","TRT02EDTM":"2022-02-12 07:11:49","AP01SDTM":"2020-06-08 23:44:46","AP01EDTM":"2021-02-12 01:11:49","AP02SDTM":"2021-02-12 01:11:49","AP02EDTM":"2022-02-12 07:11:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":614,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":652,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6441,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.47598,"AVALU":"U/L","BASE2":20.70055,"BASE":36.70284,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.22457,"PCHG2":-1.08487,"CHG":-16.22686,"PCHG":-44.21146,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-05 23:44:46","ADY":484,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-393","SUBJID":"id-393","SITEID":"JPN-17","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65965,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-07","TRTSDTM":"2020-06-08 23:44:46","TRTEDTM":"2022-02-12 07:11:49","TRT01SDTM":"2020-06-08 23:44:46","TRT01EDTM":"2021-02-12 01:11:49","TRT02SDTM":"2021-02-12 01:11:49","TRT02EDTM":"2022-02-12 07:11:49","AP01SDTM":"2020-06-08 23:44:46","AP01EDTM":"2021-02-12 01:11:49","AP02SDTM":"2021-02-12 01:11:49","AP02EDTM":"2022-02-12 07:11:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":614,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":652,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5160,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.33495,"AVALU":"mg/L","BASE2":8.33495,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-27 23:44:46","ADY":19,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-393","SUBJID":"id-393","SITEID":"JPN-17","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65965,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-07","TRTSDTM":"2020-06-08 23:44:46","TRTEDTM":"2022-02-12 07:11:49","TRT01SDTM":"2020-06-08 23:44:46","TRT01EDTM":"2021-02-12 01:11:49","TRT02SDTM":"2021-02-12 01:11:49","TRT02EDTM":"2022-02-12 07:11:49","AP01SDTM":"2020-06-08 23:44:46","AP01EDTM":"2021-02-12 01:11:49","AP02SDTM":"2021-02-12 01:11:49","AP02EDTM":"2022-02-12 07:11:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":614,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":652,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2571,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.44514,"AVALU":"mg/L","BASE2":8.33495,"BASE":8.44514,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.11019,"PCHG2":1.32204,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-23 23:44:46","ADY":45,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-393","SUBJID":"id-393","SITEID":"JPN-17","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65965,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-07","TRTSDTM":"2020-06-08 23:44:46","TRTEDTM":"2022-02-12 07:11:49","TRT01SDTM":"2020-06-08 23:44:46","TRT01EDTM":"2021-02-12 01:11:49","TRT02SDTM":"2021-02-12 01:11:49","TRT02EDTM":"2022-02-12 07:11:49","AP01SDTM":"2020-06-08 23:44:46","AP01EDTM":"2021-02-12 01:11:49","AP02SDTM":"2021-02-12 01:11:49","AP02EDTM":"2022-02-12 07:11:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":614,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":652,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3917,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.80559,"AVALU":"mg/L","BASE2":8.33495,"BASE":8.44514,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.47064,"PCHG2":17.64425,"CHG":1.36045,"PCHG":16.10925,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-07 23:44:46","ADY":182,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-393","SUBJID":"id-393","SITEID":"JPN-17","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65965,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-07","TRTSDTM":"2020-06-08 23:44:46","TRTEDTM":"2022-02-12 07:11:49","TRT01SDTM":"2020-06-08 23:44:46","TRT01EDTM":"2021-02-12 01:11:49","TRT02SDTM":"2021-02-12 01:11:49","TRT02EDTM":"2022-02-12 07:11:49","AP01SDTM":"2020-06-08 23:44:46","AP01EDTM":"2021-02-12 01:11:49","AP02SDTM":"2021-02-12 01:11:49","AP02EDTM":"2022-02-12 07:11:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":614,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":652,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6721,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.34829,"AVALU":"mg/L","BASE2":8.33495,"BASE":8.44514,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.01334,"PCHG2":12.15769,"CHG":0.90315,"PCHG":10.69427,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-05 23:44:46","ADY":211,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-393","SUBJID":"id-393","SITEID":"JPN-17","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65965,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-07","TRTSDTM":"2020-06-08 23:44:46","TRTEDTM":"2022-02-12 07:11:49","TRT01SDTM":"2020-06-08 23:44:46","TRT01EDTM":"2021-02-12 01:11:49","TRT02SDTM":"2021-02-12 01:11:49","TRT02EDTM":"2022-02-12 07:11:49","AP01SDTM":"2020-06-08 23:44:46","AP01EDTM":"2021-02-12 01:11:49","AP02SDTM":"2021-02-12 01:11:49","AP02EDTM":"2022-02-12 07:11:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":614,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":652,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5714,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.25238,"AVALU":"mg/L","BASE2":8.33495,"BASE":8.44514,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.91744,"PCHG2":11.00709,"CHG":0.80724,"PCHG":9.55868,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-12 23:44:46","ADY":218,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-393","SUBJID":"id-393","SITEID":"JPN-17","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65965,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-07","TRTSDTM":"2020-06-08 23:44:46","TRTEDTM":"2022-02-12 07:11:49","TRT01SDTM":"2020-06-08 23:44:46","TRT01EDTM":"2021-02-12 01:11:49","TRT02SDTM":"2021-02-12 01:11:49","TRT02EDTM":"2022-02-12 07:11:49","AP01SDTM":"2020-06-08 23:44:46","AP01EDTM":"2021-02-12 01:11:49","AP02SDTM":"2021-02-12 01:11:49","AP02EDTM":"2022-02-12 07:11:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":614,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":652,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6161,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.23999,"AVALU":"mg/L","BASE2":8.33495,"BASE":8.44514,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09496,"PCHG2":-1.13932,"CHG":-0.20515,"PCHG":-2.42924,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-11 23:44:46","ADY":368,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-393","SUBJID":"id-393","SITEID":"JPN-17","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65965,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-07","TRTSDTM":"2020-06-08 23:44:46","TRTEDTM":"2022-02-12 07:11:49","TRT01SDTM":"2020-06-08 23:44:46","TRT01EDTM":"2021-02-12 01:11:49","TRT02SDTM":"2021-02-12 01:11:49","TRT02EDTM":"2022-02-12 07:11:49","AP01SDTM":"2020-06-08 23:44:46","AP01EDTM":"2021-02-12 01:11:49","AP02SDTM":"2021-02-12 01:11:49","AP02EDTM":"2022-02-12 07:11:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":614,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":652,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1608,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.84551,"AVALU":"mg/L","BASE2":8.33495,"BASE":8.44514,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.51056,"PCHG2":6.12555,"CHG":0.40037,"PCHG":4.74084,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-05 23:44:46","ADY":484,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-393","SUBJID":"id-393","SITEID":"JPN-17","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65965,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-07","TRTSDTM":"2020-06-08 23:44:46","TRTEDTM":"2022-02-12 07:11:49","TRT01SDTM":"2020-06-08 23:44:46","TRT01EDTM":"2021-02-12 01:11:49","TRT02SDTM":"2021-02-12 01:11:49","TRT02EDTM":"2022-02-12 07:11:49","AP01SDTM":"2020-06-08 23:44:46","AP01EDTM":"2021-02-12 01:11:49","AP02SDTM":"2021-02-12 01:11:49","AP02EDTM":"2022-02-12 07:11:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":614,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":652,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8336,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93409,"AVALU":"g/L","BASE2":2.93409,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-27 23:44:46","ADY":19,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-393","SUBJID":"id-393","SITEID":"JPN-17","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65965,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-07","TRTSDTM":"2020-06-08 23:44:46","TRTEDTM":"2022-02-12 07:11:49","TRT01SDTM":"2020-06-08 23:44:46","TRT01EDTM":"2021-02-12 01:11:49","TRT02SDTM":"2021-02-12 01:11:49","TRT02EDTM":"2022-02-12 07:11:49","AP01SDTM":"2020-06-08 23:44:46","AP01EDTM":"2021-02-12 01:11:49","AP02SDTM":"2021-02-12 01:11:49","AP02EDTM":"2022-02-12 07:11:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":614,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":652,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":428,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82328,"AVALU":"g/L","BASE2":2.93409,"BASE":2.82328,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.11081,"PCHG2":-3.77678,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-23 23:44:46","ADY":45,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-393","SUBJID":"id-393","SITEID":"JPN-17","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65965,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-07","TRTSDTM":"2020-06-08 23:44:46","TRTEDTM":"2022-02-12 07:11:49","TRT01SDTM":"2020-06-08 23:44:46","TRT01EDTM":"2021-02-12 01:11:49","TRT02SDTM":"2021-02-12 01:11:49","TRT02EDTM":"2022-02-12 07:11:49","AP01SDTM":"2020-06-08 23:44:46","AP01EDTM":"2021-02-12 01:11:49","AP02SDTM":"2021-02-12 01:11:49","AP02EDTM":"2022-02-12 07:11:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":614,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":652,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8184,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89759,"AVALU":"g/L","BASE2":2.93409,"BASE":2.82328,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0365,"PCHG2":-1.2439,"CHG":0.07432,"PCHG":2.6323,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-07 23:44:46","ADY":182,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-393","SUBJID":"id-393","SITEID":"JPN-17","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65965,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-07","TRTSDTM":"2020-06-08 23:44:46","TRTEDTM":"2022-02-12 07:11:49","TRT01SDTM":"2020-06-08 23:44:46","TRT01EDTM":"2021-02-12 01:11:49","TRT02SDTM":"2021-02-12 01:11:49","TRT02EDTM":"2022-02-12 07:11:49","AP01SDTM":"2020-06-08 23:44:46","AP01EDTM":"2021-02-12 01:11:49","AP02SDTM":"2021-02-12 01:11:49","AP02EDTM":"2022-02-12 07:11:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":614,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":652,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3435,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99307,"AVALU":"g/L","BASE2":2.93409,"BASE":2.82328,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05898,"PCHG2":2.0101,"CHG":0.16979,"PCHG":6.01402,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-05 23:44:46","ADY":211,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-393","SUBJID":"id-393","SITEID":"JPN-17","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65965,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-07","TRTSDTM":"2020-06-08 23:44:46","TRTEDTM":"2022-02-12 07:11:49","TRT01SDTM":"2020-06-08 23:44:46","TRT01EDTM":"2021-02-12 01:11:49","TRT02SDTM":"2021-02-12 01:11:49","TRT02EDTM":"2022-02-12 07:11:49","AP01SDTM":"2020-06-08 23:44:46","AP01EDTM":"2021-02-12 01:11:49","AP02SDTM":"2021-02-12 01:11:49","AP02EDTM":"2022-02-12 07:11:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":614,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":652,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7049,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88416,"AVALU":"g/L","BASE2":2.93409,"BASE":2.82328,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04993,"PCHG2":-1.70164,"CHG":0.06089,"PCHG":2.15659,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-12 23:44:46","ADY":218,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-393","SUBJID":"id-393","SITEID":"JPN-17","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65965,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-07","TRTSDTM":"2020-06-08 23:44:46","TRTEDTM":"2022-02-12 07:11:49","TRT01SDTM":"2020-06-08 23:44:46","TRT01EDTM":"2021-02-12 01:11:49","TRT02SDTM":"2021-02-12 01:11:49","TRT02EDTM":"2022-02-12 07:11:49","AP01SDTM":"2020-06-08 23:44:46","AP01EDTM":"2021-02-12 01:11:49","AP02SDTM":"2021-02-12 01:11:49","AP02EDTM":"2022-02-12 07:11:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":614,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":652,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8341,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92553,"AVALU":"g/L","BASE2":2.93409,"BASE":2.82328,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00856,"PCHG2":-0.29163,"CHG":0.10226,"PCHG":3.62195,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-11 23:44:46","ADY":368,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-17-id-393","SUBJID":"id-393","SITEID":"JPN-17","AGE":26,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"Y","INVID":"INV ID JPN-17","INVNAM":"Dr. JPN-17 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65965,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-06-07","TRTSDTM":"2020-06-08 23:44:46","TRTEDTM":"2022-02-12 07:11:49","TRT01SDTM":"2020-06-08 23:44:46","TRT01EDTM":"2021-02-12 01:11:49","TRT02SDTM":"2021-02-12 01:11:49","TRT02EDTM":"2022-02-12 07:11:49","AP01SDTM":"2020-06-08 23:44:46","AP01EDTM":"2021-02-12 01:11:49","AP02SDTM":"2021-02-12 01:11:49","AP02EDTM":"2022-02-12 07:11:49","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":614,"DCSREAS":"DEATH","DTHDT":"2022-03-23","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":39,"LDDTHGR1":">30","LSTALVDT":"2022-03-23","DTHADY":652,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6835,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81952,"AVALU":"g/L","BASE2":2.93409,"BASE":2.82328,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11457,"PCHG2":-3.90469,"CHG":-0.00375,"PCHG":-0.13293,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-05 23:44:46","ADY":484,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-18-id-189","SUBJID":"id-189","SITEID":"JPN-18","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-18","INVNAM":"Dr. JPN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.84644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 19:54:53","TRTEDTM":"2023-09-10 13:54:53","TRT01SDTM":"2020-09-09 19:54:53","TRT01EDTM":"2022-09-10 07:54:53","TRT02SDTM":"2022-09-10 07:54:53","TRT02EDTM":"2023-09-10 13:54:53","AP01SDTM":"2020-09-09 19:54:53","AP01EDTM":"2022-09-10 07:54:53","AP02SDTM":"2022-09-10 07:54:53","AP02EDTM":"2023-09-10 13:54:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-30","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6818,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.43612,"AVALU":"U/L","BASE2":28.43612,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-12-30 19:54:53","ADY":112,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-18-id-189","SUBJID":"id-189","SITEID":"JPN-18","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-18","INVNAM":"Dr. JPN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.84644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 19:54:53","TRTEDTM":"2023-09-10 13:54:53","TRT01SDTM":"2020-09-09 19:54:53","TRT01EDTM":"2022-09-10 07:54:53","TRT02SDTM":"2022-09-10 07:54:53","TRT02EDTM":"2023-09-10 13:54:53","AP01SDTM":"2020-09-09 19:54:53","AP01EDTM":"2022-09-10 07:54:53","AP02SDTM":"2022-09-10 07:54:53","AP02EDTM":"2023-09-10 13:54:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-30","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":316,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.00228,"AVALU":"U/L","BASE2":28.43612,"BASE":0.00228,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-28.43385,"PCHG2":-99.992,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2021-10-11 19:54:53","ADY":397,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-18-id-189","SUBJID":"id-189","SITEID":"JPN-18","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-18","INVNAM":"Dr. JPN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.84644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 19:54:53","TRTEDTM":"2023-09-10 13:54:53","TRT01SDTM":"2020-09-09 19:54:53","TRT01EDTM":"2022-09-10 07:54:53","TRT02SDTM":"2022-09-10 07:54:53","TRT02EDTM":"2023-09-10 13:54:53","AP01SDTM":"2020-09-09 19:54:53","AP01EDTM":"2022-09-10 07:54:53","AP02SDTM":"2022-09-10 07:54:53","AP02EDTM":"2023-09-10 13:54:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-30","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3548,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.92293,"AVALU":"U/L","BASE2":28.43612,"BASE":0.00228,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.5132,"PCHG2":-40.48793,"CHG":16.92065,"PCHG":743422.88236,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-11-23 19:54:53","ADY":440,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-18-id-189","SUBJID":"id-189","SITEID":"JPN-18","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-18","INVNAM":"Dr. JPN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.84644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 19:54:53","TRTEDTM":"2023-09-10 13:54:53","TRT01SDTM":"2020-09-09 19:54:53","TRT01EDTM":"2022-09-10 07:54:53","TRT02SDTM":"2022-09-10 07:54:53","TRT02EDTM":"2023-09-10 13:54:53","AP01SDTM":"2020-09-09 19:54:53","AP01EDTM":"2022-09-10 07:54:53","AP02SDTM":"2022-09-10 07:54:53","AP02EDTM":"2023-09-10 13:54:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-30","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8225,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.89662,"AVALU":"U/L","BASE2":28.43612,"BASE":0.00228,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.53951,"PCHG2":-51.13041,"CHG":13.89434,"PCHG":610459.40834,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-02-28 19:54:53","ADY":537,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-18-id-189","SUBJID":"id-189","SITEID":"JPN-18","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-18","INVNAM":"Dr. JPN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.84644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 19:54:53","TRTEDTM":"2023-09-10 13:54:53","TRT01SDTM":"2020-09-09 19:54:53","TRT01EDTM":"2022-09-10 07:54:53","TRT02SDTM":"2022-09-10 07:54:53","TRT02EDTM":"2023-09-10 13:54:53","AP01SDTM":"2020-09-09 19:54:53","AP01EDTM":"2022-09-10 07:54:53","AP02SDTM":"2022-09-10 07:54:53","AP02EDTM":"2023-09-10 13:54:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-30","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4586,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.27105,"AVALU":"U/L","BASE2":28.43612,"BASE":0.00228,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-19.16507,"PCHG2":-67.39692,"CHG":9.26878,"PCHG":407231.33407,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-05-21 19:54:53","ADY":619,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-18-id-189","SUBJID":"id-189","SITEID":"JPN-18","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-18","INVNAM":"Dr. JPN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.84644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 19:54:53","TRTEDTM":"2023-09-10 13:54:53","TRT01SDTM":"2020-09-09 19:54:53","TRT01EDTM":"2022-09-10 07:54:53","TRT02SDTM":"2022-09-10 07:54:53","TRT02EDTM":"2023-09-10 13:54:53","AP01SDTM":"2020-09-09 19:54:53","AP01EDTM":"2022-09-10 07:54:53","AP02SDTM":"2022-09-10 07:54:53","AP02EDTM":"2023-09-10 13:54:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-30","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":464,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.93454,"AVALU":"U/L","BASE2":28.43612,"BASE":0.00228,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-27.50158,"PCHG2":-96.71354,"CHG":0.93227,"PCHG":40959.88591,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2023-03-21 19:54:53","ADY":923,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-18-id-189","SUBJID":"id-189","SITEID":"JPN-18","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-18","INVNAM":"Dr. JPN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.84644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 19:54:53","TRTEDTM":"2023-09-10 13:54:53","TRT01SDTM":"2020-09-09 19:54:53","TRT01EDTM":"2022-09-10 07:54:53","TRT02SDTM":"2022-09-10 07:54:53","TRT02EDTM":"2023-09-10 13:54:53","AP01SDTM":"2020-09-09 19:54:53","AP01EDTM":"2022-09-10 07:54:53","AP02SDTM":"2022-09-10 07:54:53","AP02EDTM":"2023-09-10 13:54:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-30","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2838,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.1496,"AVALU":"U/L","BASE2":28.43612,"BASE":0.00228,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.28653,"PCHG2":-15.07423,"CHG":24.14732,"PCHG":1060932.65675,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2023-04-19 19:54:53","ADY":952,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-18-id-189","SUBJID":"id-189","SITEID":"JPN-18","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-18","INVNAM":"Dr. JPN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.84644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 19:54:53","TRTEDTM":"2023-09-10 13:54:53","TRT01SDTM":"2020-09-09 19:54:53","TRT01EDTM":"2022-09-10 07:54:53","TRT02SDTM":"2022-09-10 07:54:53","TRT02EDTM":"2023-09-10 13:54:53","AP01SDTM":"2020-09-09 19:54:53","AP01EDTM":"2022-09-10 07:54:53","AP02SDTM":"2022-09-10 07:54:53","AP02EDTM":"2023-09-10 13:54:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-30","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6510,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.62561,"AVALU":"mg/L","BASE2":8.62561,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"4","ADTM":"2020-12-30 19:54:53","ADY":112,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-18-id-189","SUBJID":"id-189","SITEID":"JPN-18","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-18","INVNAM":"Dr. JPN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.84644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 19:54:53","TRTEDTM":"2023-09-10 13:54:53","TRT01SDTM":"2020-09-09 19:54:53","TRT01EDTM":"2022-09-10 07:54:53","TRT02SDTM":"2022-09-10 07:54:53","TRT02EDTM":"2023-09-10 13:54:53","AP01SDTM":"2020-09-09 19:54:53","AP01EDTM":"2022-09-10 07:54:53","AP02SDTM":"2022-09-10 07:54:53","AP02EDTM":"2023-09-10 13:54:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-30","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":679,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.07301,"AVALU":"mg/L","BASE2":8.62561,"BASE":10.07301,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.44739,"PCHG2":16.78014,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"4","BTOXGR":"4","ADTM":"2021-10-11 19:54:53","ADY":397,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-18-id-189","SUBJID":"id-189","SITEID":"JPN-18","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-18","INVNAM":"Dr. JPN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.84644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 19:54:53","TRTEDTM":"2023-09-10 13:54:53","TRT01SDTM":"2020-09-09 19:54:53","TRT01EDTM":"2022-09-10 07:54:53","TRT02SDTM":"2022-09-10 07:54:53","TRT02EDTM":"2023-09-10 13:54:53","AP01SDTM":"2020-09-09 19:54:53","AP01EDTM":"2022-09-10 07:54:53","AP02SDTM":"2022-09-10 07:54:53","AP02EDTM":"2023-09-10 13:54:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-30","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":450,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.80086,"AVALU":"mg/L","BASE2":8.62561,"BASE":10.07301,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17525,"PCHG2":2.03174,"CHG":-1.27214,"PCHG":-12.6292,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2021-11-23 19:54:53","ADY":440,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-18-id-189","SUBJID":"id-189","SITEID":"JPN-18","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-18","INVNAM":"Dr. JPN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.84644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 19:54:53","TRTEDTM":"2023-09-10 13:54:53","TRT01SDTM":"2020-09-09 19:54:53","TRT01EDTM":"2022-09-10 07:54:53","TRT02SDTM":"2022-09-10 07:54:53","TRT02EDTM":"2023-09-10 13:54:53","AP01SDTM":"2020-09-09 19:54:53","AP01EDTM":"2022-09-10 07:54:53","AP02SDTM":"2022-09-10 07:54:53","AP02EDTM":"2023-09-10 13:54:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-30","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7024,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.91741,"AVALU":"mg/L","BASE2":8.62561,"BASE":10.07301,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.2918,"PCHG2":14.97627,"CHG":-0.15559,"PCHG":-1.54467,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2022-02-28 19:54:53","ADY":537,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-18-id-189","SUBJID":"id-189","SITEID":"JPN-18","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-18","INVNAM":"Dr. JPN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.84644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 19:54:53","TRTEDTM":"2023-09-10 13:54:53","TRT01SDTM":"2020-09-09 19:54:53","TRT01EDTM":"2022-09-10 07:54:53","TRT02SDTM":"2022-09-10 07:54:53","TRT02EDTM":"2023-09-10 13:54:53","AP01SDTM":"2020-09-09 19:54:53","AP01EDTM":"2022-09-10 07:54:53","AP02SDTM":"2022-09-10 07:54:53","AP02EDTM":"2023-09-10 13:54:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-30","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4827,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.16435,"AVALU":"mg/L","BASE2":8.62561,"BASE":10.07301,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.53873,"PCHG2":6.24575,"CHG":-0.90866,"PCHG":-9.0207,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2022-05-21 19:54:53","ADY":619,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-18-id-189","SUBJID":"id-189","SITEID":"JPN-18","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-18","INVNAM":"Dr. JPN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.84644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 19:54:53","TRTEDTM":"2023-09-10 13:54:53","TRT01SDTM":"2020-09-09 19:54:53","TRT01EDTM":"2022-09-10 07:54:53","TRT02SDTM":"2022-09-10 07:54:53","TRT02EDTM":"2023-09-10 13:54:53","AP01SDTM":"2020-09-09 19:54:53","AP01EDTM":"2022-09-10 07:54:53","AP02SDTM":"2022-09-10 07:54:53","AP02EDTM":"2023-09-10 13:54:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-30","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7389,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.74195,"AVALU":"mg/L","BASE2":8.62561,"BASE":10.07301,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11633,"PCHG2":1.3487,"CHG":-1.33106,"PCHG":-13.21409,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2023-03-21 19:54:53","ADY":923,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-18-id-189","SUBJID":"id-189","SITEID":"JPN-18","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-18","INVNAM":"Dr. JPN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.84644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 19:54:53","TRTEDTM":"2023-09-10 13:54:53","TRT01SDTM":"2020-09-09 19:54:53","TRT01EDTM":"2022-09-10 07:54:53","TRT02SDTM":"2022-09-10 07:54:53","TRT02EDTM":"2023-09-10 13:54:53","AP01SDTM":"2020-09-09 19:54:53","AP01EDTM":"2022-09-10 07:54:53","AP02SDTM":"2022-09-10 07:54:53","AP02EDTM":"2023-09-10 13:54:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-30","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":539,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.71131,"AVALU":"mg/L","BASE2":8.62561,"BASE":10.07301,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0857,"PCHG2":0.99352,"CHG":-1.36169,"PCHG":-13.51824,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2023-04-19 19:54:53","ADY":952,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-18-id-189","SUBJID":"id-189","SITEID":"JPN-18","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-18","INVNAM":"Dr. JPN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.84644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 19:54:53","TRTEDTM":"2023-09-10 13:54:53","TRT01SDTM":"2020-09-09 19:54:53","TRT01EDTM":"2022-09-10 07:54:53","TRT02SDTM":"2022-09-10 07:54:53","TRT02EDTM":"2023-09-10 13:54:53","AP01SDTM":"2020-09-09 19:54:53","AP01EDTM":"2022-09-10 07:54:53","AP02SDTM":"2022-09-10 07:54:53","AP02EDTM":"2023-09-10 13:54:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-30","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6000,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85906,"AVALU":"g/L","BASE2":2.85906,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-30 19:54:53","ADY":112,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-18-id-189","SUBJID":"id-189","SITEID":"JPN-18","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-18","INVNAM":"Dr. JPN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.84644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 19:54:53","TRTEDTM":"2023-09-10 13:54:53","TRT01SDTM":"2020-09-09 19:54:53","TRT01EDTM":"2022-09-10 07:54:53","TRT02SDTM":"2022-09-10 07:54:53","TRT02EDTM":"2023-09-10 13:54:53","AP01SDTM":"2020-09-09 19:54:53","AP01EDTM":"2022-09-10 07:54:53","AP02SDTM":"2022-09-10 07:54:53","AP02EDTM":"2023-09-10 13:54:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-30","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":881,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80402,"AVALU":"g/L","BASE2":2.85906,"BASE":2.80402,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.05503,"PCHG2":-1.92492,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-11 19:54:53","ADY":397,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-18-id-189","SUBJID":"id-189","SITEID":"JPN-18","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-18","INVNAM":"Dr. JPN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.84644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 19:54:53","TRTEDTM":"2023-09-10 13:54:53","TRT01SDTM":"2020-09-09 19:54:53","TRT01EDTM":"2022-09-10 07:54:53","TRT02SDTM":"2022-09-10 07:54:53","TRT02EDTM":"2023-09-10 13:54:53","AP01SDTM":"2020-09-09 19:54:53","AP01EDTM":"2022-09-10 07:54:53","AP02SDTM":"2022-09-10 07:54:53","AP02EDTM":"2023-09-10 13:54:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-30","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6725,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88954,"AVALU":"g/L","BASE2":2.85906,"BASE":2.80402,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03049,"PCHG2":1.06626,"CHG":0.08552,"PCHG":3.04989,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-23 19:54:53","ADY":440,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-18-id-189","SUBJID":"id-189","SITEID":"JPN-18","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-18","INVNAM":"Dr. JPN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.84644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 19:54:53","TRTEDTM":"2023-09-10 13:54:53","TRT01SDTM":"2020-09-09 19:54:53","TRT01EDTM":"2022-09-10 07:54:53","TRT02SDTM":"2022-09-10 07:54:53","TRT02EDTM":"2023-09-10 13:54:53","AP01SDTM":"2020-09-09 19:54:53","AP01EDTM":"2022-09-10 07:54:53","AP02SDTM":"2022-09-10 07:54:53","AP02EDTM":"2023-09-10 13:54:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-30","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3605,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95858,"AVALU":"g/L","BASE2":2.85906,"BASE":2.80402,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09953,"PCHG2":3.48104,"CHG":0.15456,"PCHG":5.51206,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-28 19:54:53","ADY":537,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-18-id-189","SUBJID":"id-189","SITEID":"JPN-18","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-18","INVNAM":"Dr. JPN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.84644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 19:54:53","TRTEDTM":"2023-09-10 13:54:53","TRT01SDTM":"2020-09-09 19:54:53","TRT01EDTM":"2022-09-10 07:54:53","TRT02SDTM":"2022-09-10 07:54:53","TRT02EDTM":"2023-09-10 13:54:53","AP01SDTM":"2020-09-09 19:54:53","AP01EDTM":"2022-09-10 07:54:53","AP02SDTM":"2022-09-10 07:54:53","AP02EDTM":"2023-09-10 13:54:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-30","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7368,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00045,"AVALU":"g/L","BASE2":2.85906,"BASE":2.80402,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14139,"PCHG2":4.94526,"CHG":0.19642,"PCHG":7.00502,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-05-21 19:54:53","ADY":619,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-18-id-189","SUBJID":"id-189","SITEID":"JPN-18","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-18","INVNAM":"Dr. JPN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.84644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 19:54:53","TRTEDTM":"2023-09-10 13:54:53","TRT01SDTM":"2020-09-09 19:54:53","TRT01EDTM":"2022-09-10 07:54:53","TRT02SDTM":"2022-09-10 07:54:53","TRT02EDTM":"2023-09-10 13:54:53","AP01SDTM":"2020-09-09 19:54:53","AP01EDTM":"2022-09-10 07:54:53","AP02SDTM":"2022-09-10 07:54:53","AP02EDTM":"2023-09-10 13:54:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-30","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5266,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94016,"AVALU":"g/L","BASE2":2.85906,"BASE":2.80402,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0811,"PCHG2":2.83665,"CHG":0.13614,"PCHG":4.85502,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-21 19:54:53","ADY":923,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-18-id-189","SUBJID":"id-189","SITEID":"JPN-18","AGE":48,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-18","INVNAM":"Dr. JPN-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.84644,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-09 19:54:53","TRTEDTM":"2023-09-10 13:54:53","TRT01SDTM":"2020-09-09 19:54:53","TRT01EDTM":"2022-09-10 07:54:53","TRT02SDTM":"2022-09-10 07:54:53","TRT02EDTM":"2023-09-10 13:54:53","AP01SDTM":"2020-09-09 19:54:53","AP01EDTM":"2022-09-10 07:54:53","AP02SDTM":"2022-09-10 07:54:53","AP02EDTM":"2023-09-10 13:54:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-30","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3537,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88994,"AVALU":"g/L","BASE2":2.85906,"BASE":2.80402,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03088,"PCHG2":1.08007,"CHG":0.08591,"PCHG":3.06397,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-19 19:54:53","ADY":952,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-2-id-214","SUBJID":"id-214","SITEID":"JPN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-2","INVNAM":"Dr. JPN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.13205,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 08:32:27","TRTEDTM":"2023-03-29 02:32:27","TRT01SDTM":"2020-03-28 08:32:27","TRT01EDTM":"2022-03-28 20:32:27","TRT02SDTM":"2022-03-28 20:32:27","TRT02EDTM":"2023-03-29 02:32:27","AP01SDTM":"2020-03-28 08:32:27","AP01EDTM":"2022-03-28 20:32:27","AP02SDTM":"2022-03-28 20:32:27","AP02EDTM":"2023-03-29 02:32:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-27","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5646,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.14173,"AVALU":"U/L","BASE2":8.14173,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-03 08:32:27","ADY":97,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-2-id-214","SUBJID":"id-214","SITEID":"JPN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-2","INVNAM":"Dr. JPN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.13205,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 08:32:27","TRTEDTM":"2023-03-29 02:32:27","TRT01SDTM":"2020-03-28 08:32:27","TRT01EDTM":"2022-03-28 20:32:27","TRT02SDTM":"2022-03-28 20:32:27","TRT02EDTM":"2023-03-29 02:32:27","AP01SDTM":"2020-03-28 08:32:27","AP01EDTM":"2022-03-28 20:32:27","AP02SDTM":"2022-03-28 20:32:27","AP02EDTM":"2023-03-29 02:32:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-27","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8290,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.49487,"AVALU":"U/L","BASE2":8.14173,"BASE":12.49487,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":4.35313,"PCHG2":53.46691,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-10 08:32:27","ADY":135,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-2-id-214","SUBJID":"id-214","SITEID":"JPN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-2","INVNAM":"Dr. JPN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.13205,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 08:32:27","TRTEDTM":"2023-03-29 02:32:27","TRT01SDTM":"2020-03-28 08:32:27","TRT01EDTM":"2022-03-28 20:32:27","TRT02SDTM":"2022-03-28 20:32:27","TRT02EDTM":"2023-03-29 02:32:27","AP01SDTM":"2020-03-28 08:32:27","AP01EDTM":"2022-03-28 20:32:27","AP02SDTM":"2022-03-28 20:32:27","AP02EDTM":"2023-03-29 02:32:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-27","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1479,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.53345,"AVALU":"U/L","BASE2":8.14173,"BASE":12.49487,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.39172,"PCHG2":115.3528,"CHG":5.03858,"PCHG":40.32524,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-16 08:32:27","ADY":141,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-2-id-214","SUBJID":"id-214","SITEID":"JPN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-2","INVNAM":"Dr. JPN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.13205,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 08:32:27","TRTEDTM":"2023-03-29 02:32:27","TRT01SDTM":"2020-03-28 08:32:27","TRT01EDTM":"2022-03-28 20:32:27","TRT02SDTM":"2022-03-28 20:32:27","TRT02EDTM":"2023-03-29 02:32:27","AP01SDTM":"2020-03-28 08:32:27","AP01EDTM":"2022-03-28 20:32:27","AP02SDTM":"2022-03-28 20:32:27","AP02EDTM":"2023-03-29 02:32:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-27","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2877,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.8233,"AVALU":"U/L","BASE2":8.14173,"BASE":12.49487,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.68157,"PCHG2":192.60726,"CHG":11.32844,"PCHG":90.66473,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-03 08:32:27","ADY":220,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-2-id-214","SUBJID":"id-214","SITEID":"JPN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-2","INVNAM":"Dr. JPN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.13205,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 08:32:27","TRTEDTM":"2023-03-29 02:32:27","TRT01SDTM":"2020-03-28 08:32:27","TRT01EDTM":"2022-03-28 20:32:27","TRT02SDTM":"2022-03-28 20:32:27","TRT02EDTM":"2023-03-29 02:32:27","AP01SDTM":"2020-03-28 08:32:27","AP01EDTM":"2022-03-28 20:32:27","AP02SDTM":"2022-03-28 20:32:27","AP02EDTM":"2023-03-29 02:32:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-27","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5187,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.00118,"AVALU":"U/L","BASE2":8.14173,"BASE":12.49487,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.14055,"PCHG2":-50.85593,"CHG":-8.49369,"PCHG":-67.97742,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-10-18 08:32:27","ADY":569,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-2-id-214","SUBJID":"id-214","SITEID":"JPN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-2","INVNAM":"Dr. JPN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.13205,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 08:32:27","TRTEDTM":"2023-03-29 02:32:27","TRT01SDTM":"2020-03-28 08:32:27","TRT01EDTM":"2022-03-28 20:32:27","TRT02SDTM":"2022-03-28 20:32:27","TRT02EDTM":"2023-03-29 02:32:27","AP01SDTM":"2020-03-28 08:32:27","AP01EDTM":"2022-03-28 20:32:27","AP02SDTM":"2022-03-28 20:32:27","AP02EDTM":"2023-03-29 02:32:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-27","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7833,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.1394,"AVALU":"U/L","BASE2":8.14173,"BASE":12.49487,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.00234,"PCHG2":-12.3111,"CHG":-5.35547,"PCHG":-42.86136,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-25 08:32:27","ADY":1002,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-2-id-214","SUBJID":"id-214","SITEID":"JPN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-2","INVNAM":"Dr. JPN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.13205,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 08:32:27","TRTEDTM":"2023-03-29 02:32:27","TRT01SDTM":"2020-03-28 08:32:27","TRT01EDTM":"2022-03-28 20:32:27","TRT02SDTM":"2022-03-28 20:32:27","TRT02EDTM":"2023-03-29 02:32:27","AP01SDTM":"2020-03-28 08:32:27","AP01EDTM":"2022-03-28 20:32:27","AP02SDTM":"2022-03-28 20:32:27","AP02EDTM":"2023-03-29 02:32:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-27","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4087,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.9178,"AVALU":"U/L","BASE2":8.14173,"BASE":12.49487,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.77607,"PCHG2":193.76791,"CHG":11.42293,"PCHG":91.42101,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-19 08:32:27","ADY":1086,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-2-id-214","SUBJID":"id-214","SITEID":"JPN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-2","INVNAM":"Dr. JPN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.13205,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 08:32:27","TRTEDTM":"2023-03-29 02:32:27","TRT01SDTM":"2020-03-28 08:32:27","TRT01EDTM":"2022-03-28 20:32:27","TRT02SDTM":"2022-03-28 20:32:27","TRT02EDTM":"2023-03-29 02:32:27","AP01SDTM":"2020-03-28 08:32:27","AP01EDTM":"2022-03-28 20:32:27","AP02SDTM":"2022-03-28 20:32:27","AP02EDTM":"2023-03-29 02:32:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-27","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8358,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.2046,"AVALU":"mg/L","BASE2":9.2046,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-07-03 08:32:27","ADY":97,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-2-id-214","SUBJID":"id-214","SITEID":"JPN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-2","INVNAM":"Dr. JPN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.13205,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 08:32:27","TRTEDTM":"2023-03-29 02:32:27","TRT01SDTM":"2020-03-28 08:32:27","TRT01EDTM":"2022-03-28 20:32:27","TRT02SDTM":"2022-03-28 20:32:27","TRT02EDTM":"2023-03-29 02:32:27","AP01SDTM":"2020-03-28 08:32:27","AP01EDTM":"2022-03-28 20:32:27","AP02SDTM":"2022-03-28 20:32:27","AP02EDTM":"2023-03-29 02:32:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-27","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4617,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.45642,"AVALU":"mg/L","BASE2":9.2046,"BASE":7.45642,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.74818,"PCHG2":-18.99249,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2020-08-10 08:32:27","ADY":135,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-2-id-214","SUBJID":"id-214","SITEID":"JPN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-2","INVNAM":"Dr. JPN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.13205,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 08:32:27","TRTEDTM":"2023-03-29 02:32:27","TRT01SDTM":"2020-03-28 08:32:27","TRT01EDTM":"2022-03-28 20:32:27","TRT02SDTM":"2022-03-28 20:32:27","TRT02EDTM":"2023-03-29 02:32:27","AP01SDTM":"2020-03-28 08:32:27","AP01EDTM":"2022-03-28 20:32:27","AP02SDTM":"2022-03-28 20:32:27","AP02EDTM":"2023-03-29 02:32:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-27","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6123,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.14903,"AVALU":"mg/L","BASE2":9.2046,"BASE":7.45642,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.05557,"PCHG2":-22.33199,"CHG":-0.30739,"PCHG":-4.12246,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-4","BTOXGR":"-1","ADTM":"2020-08-16 08:32:27","ADY":141,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-2-id-214","SUBJID":"id-214","SITEID":"JPN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-2","INVNAM":"Dr. JPN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.13205,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 08:32:27","TRTEDTM":"2023-03-29 02:32:27","TRT01SDTM":"2020-03-28 08:32:27","TRT01EDTM":"2022-03-28 20:32:27","TRT02SDTM":"2022-03-28 20:32:27","TRT02EDTM":"2023-03-29 02:32:27","AP01SDTM":"2020-03-28 08:32:27","AP01EDTM":"2022-03-28 20:32:27","AP02SDTM":"2022-03-28 20:32:27","AP02EDTM":"2023-03-29 02:32:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-27","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7752,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.95302,"AVALU":"mg/L","BASE2":9.2046,"BASE":7.45642,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.74842,"PCHG2":8.13089,"CHG":2.4966,"PCHG":33.48255,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-11-03 08:32:27","ADY":220,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-2-id-214","SUBJID":"id-214","SITEID":"JPN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-2","INVNAM":"Dr. JPN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.13205,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 08:32:27","TRTEDTM":"2023-03-29 02:32:27","TRT01SDTM":"2020-03-28 08:32:27","TRT01EDTM":"2022-03-28 20:32:27","TRT02SDTM":"2022-03-28 20:32:27","TRT02EDTM":"2023-03-29 02:32:27","AP01SDTM":"2020-03-28 08:32:27","AP01EDTM":"2022-03-28 20:32:27","AP02SDTM":"2022-03-28 20:32:27","AP02EDTM":"2023-03-29 02:32:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-27","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4626,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.61767,"AVALU":"mg/L","BASE2":9.2046,"BASE":7.45642,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.58693,"PCHG2":-6.37653,"CHG":1.16125,"PCHG":15.57381,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-10-18 08:32:27","ADY":569,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-2-id-214","SUBJID":"id-214","SITEID":"JPN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-2","INVNAM":"Dr. JPN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.13205,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 08:32:27","TRTEDTM":"2023-03-29 02:32:27","TRT01SDTM":"2020-03-28 08:32:27","TRT01EDTM":"2022-03-28 20:32:27","TRT02SDTM":"2022-03-28 20:32:27","TRT02EDTM":"2023-03-29 02:32:27","AP01SDTM":"2020-03-28 08:32:27","AP01EDTM":"2022-03-28 20:32:27","AP02SDTM":"2022-03-28 20:32:27","AP02EDTM":"2023-03-29 02:32:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-27","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2064,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.37275,"AVALU":"mg/L","BASE2":9.2046,"BASE":7.45642,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.83186,"PCHG2":-19.90155,"CHG":-0.08368,"PCHG":-1.12219,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2022-12-25 08:32:27","ADY":1002,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-2-id-214","SUBJID":"id-214","SITEID":"JPN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-2","INVNAM":"Dr. JPN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.13205,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 08:32:27","TRTEDTM":"2023-03-29 02:32:27","TRT01SDTM":"2020-03-28 08:32:27","TRT01EDTM":"2022-03-28 20:32:27","TRT02SDTM":"2022-03-28 20:32:27","TRT02EDTM":"2023-03-29 02:32:27","AP01SDTM":"2020-03-28 08:32:27","AP01EDTM":"2022-03-28 20:32:27","AP02SDTM":"2022-03-28 20:32:27","AP02EDTM":"2023-03-29 02:32:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-27","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2638,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.53473,"AVALU":"mg/L","BASE2":9.2046,"BASE":7.45642,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.66987,"PCHG2":-7.27761,"CHG":1.07831,"PCHG":14.46147,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2023-03-19 08:32:27","ADY":1086,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-2-id-214","SUBJID":"id-214","SITEID":"JPN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-2","INVNAM":"Dr. JPN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.13205,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 08:32:27","TRTEDTM":"2023-03-29 02:32:27","TRT01SDTM":"2020-03-28 08:32:27","TRT01EDTM":"2022-03-28 20:32:27","TRT02SDTM":"2022-03-28 20:32:27","TRT02EDTM":"2023-03-29 02:32:27","AP01SDTM":"2020-03-28 08:32:27","AP01EDTM":"2022-03-28 20:32:27","AP02SDTM":"2022-03-28 20:32:27","AP02EDTM":"2023-03-29 02:32:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-27","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":31,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85611,"AVALU":"g/L","BASE2":2.85611,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-03 08:32:27","ADY":97,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-2-id-214","SUBJID":"id-214","SITEID":"JPN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-2","INVNAM":"Dr. JPN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.13205,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 08:32:27","TRTEDTM":"2023-03-29 02:32:27","TRT01SDTM":"2020-03-28 08:32:27","TRT01EDTM":"2022-03-28 20:32:27","TRT02SDTM":"2022-03-28 20:32:27","TRT02EDTM":"2023-03-29 02:32:27","AP01SDTM":"2020-03-28 08:32:27","AP01EDTM":"2022-03-28 20:32:27","AP02SDTM":"2022-03-28 20:32:27","AP02EDTM":"2023-03-29 02:32:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-27","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3804,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92471,"AVALU":"g/L","BASE2":2.85611,"BASE":2.92471,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.06859,"PCHG2":2.40167,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-10 08:32:27","ADY":135,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-2-id-214","SUBJID":"id-214","SITEID":"JPN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-2","INVNAM":"Dr. JPN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.13205,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 08:32:27","TRTEDTM":"2023-03-29 02:32:27","TRT01SDTM":"2020-03-28 08:32:27","TRT01EDTM":"2022-03-28 20:32:27","TRT02SDTM":"2022-03-28 20:32:27","TRT02EDTM":"2023-03-29 02:32:27","AP01SDTM":"2020-03-28 08:32:27","AP01EDTM":"2022-03-28 20:32:27","AP02SDTM":"2022-03-28 20:32:27","AP02EDTM":"2023-03-29 02:32:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-27","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7825,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.72285,"AVALU":"g/L","BASE2":2.85611,"BASE":2.92471,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13326,"PCHG2":-4.66572,"CHG":-0.20185,"PCHG":-6.90164,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-16 08:32:27","ADY":141,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-2-id-214","SUBJID":"id-214","SITEID":"JPN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-2","INVNAM":"Dr. JPN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.13205,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 08:32:27","TRTEDTM":"2023-03-29 02:32:27","TRT01SDTM":"2020-03-28 08:32:27","TRT01EDTM":"2022-03-28 20:32:27","TRT02SDTM":"2022-03-28 20:32:27","TRT02EDTM":"2023-03-29 02:32:27","AP01SDTM":"2020-03-28 08:32:27","AP01EDTM":"2022-03-28 20:32:27","AP02SDTM":"2022-03-28 20:32:27","AP02EDTM":"2023-03-29 02:32:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-27","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2608,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.756,"AVALU":"g/L","BASE2":2.85611,"BASE":2.92471,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10012,"PCHG2":-3.50532,"CHG":-0.16871,"PCHG":-5.76846,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-03 08:32:27","ADY":220,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-2-id-214","SUBJID":"id-214","SITEID":"JPN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-2","INVNAM":"Dr. JPN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.13205,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 08:32:27","TRTEDTM":"2023-03-29 02:32:27","TRT01SDTM":"2020-03-28 08:32:27","TRT01EDTM":"2022-03-28 20:32:27","TRT02SDTM":"2022-03-28 20:32:27","TRT02EDTM":"2023-03-29 02:32:27","AP01SDTM":"2020-03-28 08:32:27","AP01EDTM":"2022-03-28 20:32:27","AP02SDTM":"2022-03-28 20:32:27","AP02EDTM":"2023-03-29 02:32:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-27","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7873,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9673,"AVALU":"g/L","BASE2":2.85611,"BASE":2.92471,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11119,"PCHG2":3.89293,"CHG":0.04259,"PCHG":1.45628,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-18 08:32:27","ADY":569,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-2-id-214","SUBJID":"id-214","SITEID":"JPN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-2","INVNAM":"Dr. JPN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.13205,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 08:32:27","TRTEDTM":"2023-03-29 02:32:27","TRT01SDTM":"2020-03-28 08:32:27","TRT01EDTM":"2022-03-28 20:32:27","TRT02SDTM":"2022-03-28 20:32:27","TRT02EDTM":"2023-03-29 02:32:27","AP01SDTM":"2020-03-28 08:32:27","AP01EDTM":"2022-03-28 20:32:27","AP02SDTM":"2022-03-28 20:32:27","AP02EDTM":"2023-03-29 02:32:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-27","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2249,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.73064,"AVALU":"g/L","BASE2":2.85611,"BASE":2.92471,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12547,"PCHG2":-4.39314,"CHG":-0.19407,"PCHG":-6.63545,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-25 08:32:27","ADY":1002,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-2-id-214","SUBJID":"id-214","SITEID":"JPN-2","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-2","INVNAM":"Dr. JPN-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.13205,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-26","TRTSDTM":"2020-03-28 08:32:27","TRTEDTM":"2023-03-29 02:32:27","TRT01SDTM":"2020-03-28 08:32:27","TRT01EDTM":"2022-03-28 20:32:27","TRT02SDTM":"2022-03-28 20:32:27","TRT02EDTM":"2023-03-29 02:32:27","AP01SDTM":"2020-03-28 08:32:27","AP01EDTM":"2022-03-28 20:32:27","AP02SDTM":"2022-03-28 20:32:27","AP02EDTM":"2023-03-29 02:32:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-29","EOSDY":1096,"LSTALVDT":"2023-04-27","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5693,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84525,"AVALU":"g/L","BASE2":2.85611,"BASE":2.92471,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01086,"PCHG2":-0.38023,"CHG":-0.07945,"PCHG":-2.71666,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-19 08:32:27","ADY":1086,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-3-id-109","SUBJID":"id-109","SITEID":"JPN-3","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-3","INVNAM":"Dr. JPN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.20387,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-17 05:30:19","TRTEDTM":"2022-02-16 01:43:40","TRT01SDTM":"2019-10-17 05:30:19","TRT01EDTM":"2021-02-15 19:43:40","TRT02SDTM":"2021-02-15 19:43:40","TRT02EDTM":"2022-02-16 01:43:40","AP01SDTM":"2019-10-17 05:30:19","AP01EDTM":"2021-02-15 19:43:40","AP02SDTM":"2021-02-15 19:43:40","AP02EDTM":"2022-02-16 01:43:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":853,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-08","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":612,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.12666,"AVALU":"U/L","BASE2":25.12666,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-11 05:30:19","ADY":117,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-3-id-109","SUBJID":"id-109","SITEID":"JPN-3","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-3","INVNAM":"Dr. JPN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.20387,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-17 05:30:19","TRTEDTM":"2022-02-16 01:43:40","TRT01SDTM":"2019-10-17 05:30:19","TRT01EDTM":"2021-02-15 19:43:40","TRT02SDTM":"2021-02-15 19:43:40","TRT02EDTM":"2022-02-16 01:43:40","AP01SDTM":"2019-10-17 05:30:19","AP01EDTM":"2021-02-15 19:43:40","AP02SDTM":"2021-02-15 19:43:40","AP02EDTM":"2022-02-16 01:43:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":853,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-08","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4440,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.61595,"AVALU":"U/L","BASE2":25.12666,"BASE":11.61595,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-13.51071,"PCHG2":-53.77041,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-02 05:30:19","ADY":229,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-3-id-109","SUBJID":"id-109","SITEID":"JPN-3","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-3","INVNAM":"Dr. JPN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.20387,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-17 05:30:19","TRTEDTM":"2022-02-16 01:43:40","TRT01SDTM":"2019-10-17 05:30:19","TRT01EDTM":"2021-02-15 19:43:40","TRT02SDTM":"2021-02-15 19:43:40","TRT02EDTM":"2022-02-16 01:43:40","AP01SDTM":"2019-10-17 05:30:19","AP01EDTM":"2021-02-15 19:43:40","AP02SDTM":"2021-02-15 19:43:40","AP02EDTM":"2022-02-16 01:43:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":853,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-08","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6783,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.73647,"AVALU":"U/L","BASE2":25.12666,"BASE":11.61595,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-24.39019,"PCHG2":-97.06895,"CHG":-10.87948,"PCHG":-93.6598,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-07-24 05:30:19","ADY":281,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-3-id-109","SUBJID":"id-109","SITEID":"JPN-3","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-3","INVNAM":"Dr. JPN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.20387,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-17 05:30:19","TRTEDTM":"2022-02-16 01:43:40","TRT01SDTM":"2019-10-17 05:30:19","TRT01EDTM":"2021-02-15 19:43:40","TRT02SDTM":"2021-02-15 19:43:40","TRT02EDTM":"2022-02-16 01:43:40","AP01SDTM":"2019-10-17 05:30:19","AP01EDTM":"2021-02-15 19:43:40","AP02SDTM":"2021-02-15 19:43:40","AP02EDTM":"2022-02-16 01:43:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":853,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-08","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5555,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.95305,"AVALU":"U/L","BASE2":25.12666,"BASE":11.61595,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.17362,"PCHG2":-64.36834,"CHG":-2.66291,"PCHG":-22.92457,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-07 05:30:19","ADY":295,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-3-id-109","SUBJID":"id-109","SITEID":"JPN-3","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-3","INVNAM":"Dr. JPN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.20387,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-17 05:30:19","TRTEDTM":"2022-02-16 01:43:40","TRT01SDTM":"2019-10-17 05:30:19","TRT01EDTM":"2021-02-15 19:43:40","TRT02SDTM":"2021-02-15 19:43:40","TRT02EDTM":"2022-02-16 01:43:40","AP01SDTM":"2019-10-17 05:30:19","AP01EDTM":"2021-02-15 19:43:40","AP02SDTM":"2021-02-15 19:43:40","AP02EDTM":"2022-02-16 01:43:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":853,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-08","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4709,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.96516,"AVALU":"U/L","BASE2":25.12666,"BASE":11.61595,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-21.16151,"PCHG2":-84.21933,"CHG":-7.6508,"PCHG":-65.86456,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-11-13 05:30:19","ADY":393,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-3-id-109","SUBJID":"id-109","SITEID":"JPN-3","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-3","INVNAM":"Dr. JPN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.20387,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-17 05:30:19","TRTEDTM":"2022-02-16 01:43:40","TRT01SDTM":"2019-10-17 05:30:19","TRT01EDTM":"2021-02-15 19:43:40","TRT02SDTM":"2021-02-15 19:43:40","TRT02EDTM":"2022-02-16 01:43:40","AP01SDTM":"2019-10-17 05:30:19","AP01EDTM":"2021-02-15 19:43:40","AP02SDTM":"2021-02-15 19:43:40","AP02EDTM":"2022-02-16 01:43:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":853,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-08","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6660,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.6514,"AVALU":"U/L","BASE2":25.12666,"BASE":11.61595,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.47527,"PCHG2":-65.56886,"CHG":-2.96456,"PCHG":-25.52142,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-26 05:30:19","ADY":436,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-3-id-109","SUBJID":"id-109","SITEID":"JPN-3","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-3","INVNAM":"Dr. JPN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.20387,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-17 05:30:19","TRTEDTM":"2022-02-16 01:43:40","TRT01SDTM":"2019-10-17 05:30:19","TRT01EDTM":"2021-02-15 19:43:40","TRT02SDTM":"2021-02-15 19:43:40","TRT02EDTM":"2022-02-16 01:43:40","AP01SDTM":"2019-10-17 05:30:19","AP01EDTM":"2021-02-15 19:43:40","AP02SDTM":"2021-02-15 19:43:40","AP02EDTM":"2022-02-16 01:43:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":853,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-08","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1493,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.27882,"AVALU":"U/L","BASE2":25.12666,"BASE":11.61595,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.84785,"PCHG2":-19.29364,"CHG":8.66286,"PCHG":74.57729,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-20 05:30:19","ADY":492,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-3-id-109","SUBJID":"id-109","SITEID":"JPN-3","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-3","INVNAM":"Dr. JPN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.20387,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-17 05:30:19","TRTEDTM":"2022-02-16 01:43:40","TRT01SDTM":"2019-10-17 05:30:19","TRT01EDTM":"2021-02-15 19:43:40","TRT02SDTM":"2021-02-15 19:43:40","TRT02EDTM":"2022-02-16 01:43:40","AP01SDTM":"2019-10-17 05:30:19","AP01EDTM":"2021-02-15 19:43:40","AP02SDTM":"2021-02-15 19:43:40","AP02EDTM":"2022-02-16 01:43:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":853,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-08","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6944,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.89541,"AVALU":"mg/L","BASE2":11.89541,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-02-11 05:30:19","ADY":117,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-3-id-109","SUBJID":"id-109","SITEID":"JPN-3","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-3","INVNAM":"Dr. JPN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.20387,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-17 05:30:19","TRTEDTM":"2022-02-16 01:43:40","TRT01SDTM":"2019-10-17 05:30:19","TRT01EDTM":"2021-02-15 19:43:40","TRT02SDTM":"2021-02-15 19:43:40","TRT02EDTM":"2022-02-16 01:43:40","AP01SDTM":"2019-10-17 05:30:19","AP01EDTM":"2021-02-15 19:43:40","AP02SDTM":"2021-02-15 19:43:40","AP02EDTM":"2022-02-16 01:43:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":853,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-08","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5901,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.76824,"AVALU":"mg/L","BASE2":11.89541,"BASE":9.76824,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.12717,"PCHG2":-17.8823,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-02 05:30:19","ADY":229,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-3-id-109","SUBJID":"id-109","SITEID":"JPN-3","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-3","INVNAM":"Dr. JPN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.20387,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-17 05:30:19","TRTEDTM":"2022-02-16 01:43:40","TRT01SDTM":"2019-10-17 05:30:19","TRT01EDTM":"2021-02-15 19:43:40","TRT02SDTM":"2021-02-15 19:43:40","TRT02EDTM":"2022-02-16 01:43:40","AP01SDTM":"2019-10-17 05:30:19","AP01EDTM":"2021-02-15 19:43:40","AP02SDTM":"2021-02-15 19:43:40","AP02EDTM":"2022-02-16 01:43:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":853,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-08","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6356,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.08836,"AVALU":"mg/L","BASE2":11.89541,"BASE":9.76824,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.80705,"PCHG2":-15.19116,"CHG":0.32012,"PCHG":3.27718,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-07-24 05:30:19","ADY":281,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-3-id-109","SUBJID":"id-109","SITEID":"JPN-3","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-3","INVNAM":"Dr. JPN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.20387,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-17 05:30:19","TRTEDTM":"2022-02-16 01:43:40","TRT01SDTM":"2019-10-17 05:30:19","TRT01EDTM":"2021-02-15 19:43:40","TRT02SDTM":"2021-02-15 19:43:40","TRT02EDTM":"2022-02-16 01:43:40","AP01SDTM":"2019-10-17 05:30:19","AP01EDTM":"2021-02-15 19:43:40","AP02SDTM":"2021-02-15 19:43:40","AP02EDTM":"2022-02-16 01:43:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":853,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-08","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3581,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.50184,"AVALU":"mg/L","BASE2":11.89541,"BASE":9.76824,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.39356,"PCHG2":-28.52836,"CHG":-1.26639,"PCHG":-12.96439,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-07 05:30:19","ADY":295,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-3-id-109","SUBJID":"id-109","SITEID":"JPN-3","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-3","INVNAM":"Dr. JPN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.20387,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-17 05:30:19","TRTEDTM":"2022-02-16 01:43:40","TRT01SDTM":"2019-10-17 05:30:19","TRT01EDTM":"2021-02-15 19:43:40","TRT02SDTM":"2021-02-15 19:43:40","TRT02EDTM":"2022-02-16 01:43:40","AP01SDTM":"2019-10-17 05:30:19","AP01EDTM":"2021-02-15 19:43:40","AP02SDTM":"2021-02-15 19:43:40","AP02EDTM":"2022-02-16 01:43:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":853,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-08","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7655,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.33348,"AVALU":"mg/L","BASE2":11.89541,"BASE":9.76824,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.56192,"PCHG2":-21.53708,"CHG":-0.43475,"PCHG":-4.45066,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-13 05:30:19","ADY":393,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-3-id-109","SUBJID":"id-109","SITEID":"JPN-3","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-3","INVNAM":"Dr. JPN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.20387,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-17 05:30:19","TRTEDTM":"2022-02-16 01:43:40","TRT01SDTM":"2019-10-17 05:30:19","TRT01EDTM":"2021-02-15 19:43:40","TRT02SDTM":"2021-02-15 19:43:40","TRT02EDTM":"2022-02-16 01:43:40","AP01SDTM":"2019-10-17 05:30:19","AP01EDTM":"2021-02-15 19:43:40","AP02SDTM":"2021-02-15 19:43:40","AP02EDTM":"2022-02-16 01:43:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":853,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-08","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5044,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.70462,"AVALU":"mg/L","BASE2":11.89541,"BASE":9.76824,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.19079,"PCHG2":-18.41709,"CHG":-0.06362,"PCHG":-0.65125,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-26 05:30:19","ADY":436,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-3-id-109","SUBJID":"id-109","SITEID":"JPN-3","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-3","INVNAM":"Dr. JPN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.20387,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-17 05:30:19","TRTEDTM":"2022-02-16 01:43:40","TRT01SDTM":"2019-10-17 05:30:19","TRT01EDTM":"2021-02-15 19:43:40","TRT02SDTM":"2021-02-15 19:43:40","TRT02EDTM":"2022-02-16 01:43:40","AP01SDTM":"2019-10-17 05:30:19","AP01EDTM":"2021-02-15 19:43:40","AP02SDTM":"2021-02-15 19:43:40","AP02EDTM":"2022-02-16 01:43:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":853,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-08","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1701,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.78202,"AVALU":"mg/L","BASE2":11.89541,"BASE":9.76824,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.11339,"PCHG2":-34.57967,"CHG":-1.98622,"PCHG":-20.33346,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-02-20 05:30:19","ADY":492,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-3-id-109","SUBJID":"id-109","SITEID":"JPN-3","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-3","INVNAM":"Dr. JPN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.20387,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-17 05:30:19","TRTEDTM":"2022-02-16 01:43:40","TRT01SDTM":"2019-10-17 05:30:19","TRT01EDTM":"2021-02-15 19:43:40","TRT02SDTM":"2021-02-15 19:43:40","TRT02EDTM":"2022-02-16 01:43:40","AP01SDTM":"2019-10-17 05:30:19","AP01EDTM":"2021-02-15 19:43:40","AP02SDTM":"2021-02-15 19:43:40","AP02EDTM":"2022-02-16 01:43:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":853,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-08","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":734,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88587,"AVALU":"g/L","BASE2":2.88587,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-11 05:30:19","ADY":117,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-3-id-109","SUBJID":"id-109","SITEID":"JPN-3","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-3","INVNAM":"Dr. JPN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.20387,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-17 05:30:19","TRTEDTM":"2022-02-16 01:43:40","TRT01SDTM":"2019-10-17 05:30:19","TRT01EDTM":"2021-02-15 19:43:40","TRT02SDTM":"2021-02-15 19:43:40","TRT02EDTM":"2022-02-16 01:43:40","AP01SDTM":"2019-10-17 05:30:19","AP01EDTM":"2021-02-15 19:43:40","AP02SDTM":"2021-02-15 19:43:40","AP02EDTM":"2022-02-16 01:43:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":853,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-08","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3797,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87979,"AVALU":"g/L","BASE2":2.88587,"BASE":2.87979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.00608,"PCHG2":-0.21059,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-02 05:30:19","ADY":229,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-3-id-109","SUBJID":"id-109","SITEID":"JPN-3","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-3","INVNAM":"Dr. JPN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.20387,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-17 05:30:19","TRTEDTM":"2022-02-16 01:43:40","TRT01SDTM":"2019-10-17 05:30:19","TRT01EDTM":"2021-02-15 19:43:40","TRT02SDTM":"2021-02-15 19:43:40","TRT02EDTM":"2022-02-16 01:43:40","AP01SDTM":"2019-10-17 05:30:19","AP01EDTM":"2021-02-15 19:43:40","AP02SDTM":"2021-02-15 19:43:40","AP02EDTM":"2022-02-16 01:43:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":853,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-08","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3111,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.72744,"AVALU":"g/L","BASE2":2.88587,"BASE":2.87979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15843,"PCHG2":-5.4898,"CHG":-0.15235,"PCHG":-5.29035,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-24 05:30:19","ADY":281,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-3-id-109","SUBJID":"id-109","SITEID":"JPN-3","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-3","INVNAM":"Dr. JPN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.20387,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-17 05:30:19","TRTEDTM":"2022-02-16 01:43:40","TRT01SDTM":"2019-10-17 05:30:19","TRT01EDTM":"2021-02-15 19:43:40","TRT02SDTM":"2021-02-15 19:43:40","TRT02EDTM":"2022-02-16 01:43:40","AP01SDTM":"2019-10-17 05:30:19","AP01EDTM":"2021-02-15 19:43:40","AP02SDTM":"2021-02-15 19:43:40","AP02EDTM":"2022-02-16 01:43:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":853,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-08","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5909,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96814,"AVALU":"g/L","BASE2":2.88587,"BASE":2.87979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08226,"PCHG2":2.85061,"CHG":0.08834,"PCHG":3.06766,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-07 05:30:19","ADY":295,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-3-id-109","SUBJID":"id-109","SITEID":"JPN-3","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-3","INVNAM":"Dr. JPN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.20387,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-17 05:30:19","TRTEDTM":"2022-02-16 01:43:40","TRT01SDTM":"2019-10-17 05:30:19","TRT01EDTM":"2021-02-15 19:43:40","TRT02SDTM":"2021-02-15 19:43:40","TRT02EDTM":"2022-02-16 01:43:40","AP01SDTM":"2019-10-17 05:30:19","AP01EDTM":"2021-02-15 19:43:40","AP02SDTM":"2021-02-15 19:43:40","AP02EDTM":"2022-02-16 01:43:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":853,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-08","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5403,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90414,"AVALU":"g/L","BASE2":2.88587,"BASE":2.87979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01827,"PCHG2":0.63303,"CHG":0.02435,"PCHG":0.8454,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-13 05:30:19","ADY":393,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-3-id-109","SUBJID":"id-109","SITEID":"JPN-3","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-3","INVNAM":"Dr. JPN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.20387,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-17 05:30:19","TRTEDTM":"2022-02-16 01:43:40","TRT01SDTM":"2019-10-17 05:30:19","TRT01EDTM":"2021-02-15 19:43:40","TRT02SDTM":"2021-02-15 19:43:40","TRT02EDTM":"2022-02-16 01:43:40","AP01SDTM":"2019-10-17 05:30:19","AP01EDTM":"2021-02-15 19:43:40","AP02SDTM":"2021-02-15 19:43:40","AP02EDTM":"2022-02-16 01:43:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":853,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-08","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2985,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82327,"AVALU":"g/L","BASE2":2.88587,"BASE":2.87979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06261,"PCHG2":-2.16941,"CHG":-0.05653,"PCHG":-1.96296,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-26 05:30:19","ADY":436,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-3-id-109","SUBJID":"id-109","SITEID":"JPN-3","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-3","INVNAM":"Dr. JPN-3 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":9.20387,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-10-16","TRTSDTM":"2019-10-17 05:30:19","TRTEDTM":"2022-02-16 01:43:40","TRT01SDTM":"2019-10-17 05:30:19","TRT01EDTM":"2021-02-15 19:43:40","TRT02SDTM":"2021-02-15 19:43:40","TRT02EDTM":"2022-02-16 01:43:40","AP01SDTM":"2019-10-17 05:30:19","AP01EDTM":"2021-02-15 19:43:40","AP02SDTM":"2021-02-15 19:43:40","AP02EDTM":"2022-02-16 01:43:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":853,"DCSREAS":"WITHDRAWAL BY SUBJECT","LSTALVDT":"2022-03-08","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4554,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88912,"AVALU":"g/L","BASE2":2.88587,"BASE":2.87979,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00325,"PCHG2":0.11255,"CHG":0.00933,"PCHG":0.32382,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-20 05:30:19","ADY":492,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-252","SUBJID":"id-252","SITEID":"JPN-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54319,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-16 05:04:34","TRTEDTM":"2023-10-16 23:04:34","TRT01SDTM":"2020-10-16 05:04:34","TRT01EDTM":"2022-10-16 17:04:34","TRT02SDTM":"2022-10-16 17:04:34","TRT02EDTM":"2023-10-16 23:04:34","AP01SDTM":"2020-10-16 05:04:34","AP01EDTM":"2022-10-16 17:04:34","AP02SDTM":"2022-10-16 17:04:34","AP02EDTM":"2023-10-16 23:04:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-16","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4969,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.30918,"AVALU":"U/L","BASE2":2.30918,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-07-19 05:04:34","ADY":276,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-252","SUBJID":"id-252","SITEID":"JPN-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54319,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-16 05:04:34","TRTEDTM":"2023-10-16 23:04:34","TRT01SDTM":"2020-10-16 05:04:34","TRT01EDTM":"2022-10-16 17:04:34","TRT02SDTM":"2022-10-16 17:04:34","TRT02EDTM":"2023-10-16 23:04:34","AP01SDTM":"2020-10-16 05:04:34","AP01EDTM":"2022-10-16 17:04:34","AP02SDTM":"2022-10-16 17:04:34","AP02EDTM":"2023-10-16 23:04:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-16","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7965,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.92051,"AVALU":"U/L","BASE2":2.30918,"BASE":28.92051,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":26.61133,"PCHG2":1152.41553,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-08 05:04:34","ADY":418,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-252","SUBJID":"id-252","SITEID":"JPN-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54319,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-16 05:04:34","TRTEDTM":"2023-10-16 23:04:34","TRT01SDTM":"2020-10-16 05:04:34","TRT01EDTM":"2022-10-16 17:04:34","TRT02SDTM":"2022-10-16 17:04:34","TRT02EDTM":"2023-10-16 23:04:34","AP01SDTM":"2020-10-16 05:04:34","AP01EDTM":"2022-10-16 17:04:34","AP02SDTM":"2022-10-16 17:04:34","AP02EDTM":"2023-10-16 23:04:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-16","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7722,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.22648,"AVALU":"U/L","BASE2":2.30918,"BASE":28.92051,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.91731,"PCHG2":689.30608,"CHG":-10.69402,"PCHG":-36.9773,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-07 05:04:34","ADY":538,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-252","SUBJID":"id-252","SITEID":"JPN-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54319,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-16 05:04:34","TRTEDTM":"2023-10-16 23:04:34","TRT01SDTM":"2020-10-16 05:04:34","TRT01EDTM":"2022-10-16 17:04:34","TRT02SDTM":"2022-10-16 17:04:34","TRT02EDTM":"2023-10-16 23:04:34","AP01SDTM":"2020-10-16 05:04:34","AP01EDTM":"2022-10-16 17:04:34","AP02SDTM":"2022-10-16 17:04:34","AP02EDTM":"2023-10-16 23:04:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-16","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6261,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.97105,"AVALU":"U/L","BASE2":2.30918,"BASE":28.92051,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.66187,"PCHG2":71.96822,"CHG":-24.94945,"PCHG":-86.26908,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-06-19 05:04:34","ADY":611,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-252","SUBJID":"id-252","SITEID":"JPN-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54319,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-16 05:04:34","TRTEDTM":"2023-10-16 23:04:34","TRT01SDTM":"2020-10-16 05:04:34","TRT01EDTM":"2022-10-16 17:04:34","TRT02SDTM":"2022-10-16 17:04:34","TRT02EDTM":"2023-10-16 23:04:34","AP01SDTM":"2020-10-16 05:04:34","AP01EDTM":"2022-10-16 17:04:34","AP02SDTM":"2022-10-16 17:04:34","AP02EDTM":"2023-10-16 23:04:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-16","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2342,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.17913,"AVALU":"U/L","BASE2":2.30918,"BASE":28.92051,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":28.86995,"PCHG2":1250.22639,"CHG":2.25863,"PCHG":7.80978,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-08 05:04:34","ADY":845,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-252","SUBJID":"id-252","SITEID":"JPN-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54319,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-16 05:04:34","TRTEDTM":"2023-10-16 23:04:34","TRT01SDTM":"2020-10-16 05:04:34","TRT01EDTM":"2022-10-16 17:04:34","TRT02SDTM":"2022-10-16 17:04:34","TRT02EDTM":"2023-10-16 23:04:34","AP01SDTM":"2020-10-16 05:04:34","AP01EDTM":"2022-10-16 17:04:34","AP02SDTM":"2022-10-16 17:04:34","AP02EDTM":"2023-10-16 23:04:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-16","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1059,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.13716,"AVALU":"U/L","BASE2":2.30918,"BASE":28.92051,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.82798,"PCHG2":382.29963,"CHG":-17.78335,"PCHG":-61.49045,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-09 05:04:34","ADY":846,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-252","SUBJID":"id-252","SITEID":"JPN-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54319,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-16 05:04:34","TRTEDTM":"2023-10-16 23:04:34","TRT01SDTM":"2020-10-16 05:04:34","TRT01EDTM":"2022-10-16 17:04:34","TRT02SDTM":"2022-10-16 17:04:34","TRT02EDTM":"2023-10-16 23:04:34","AP01SDTM":"2020-10-16 05:04:34","AP01EDTM":"2022-10-16 17:04:34","AP02SDTM":"2022-10-16 17:04:34","AP02EDTM":"2023-10-16 23:04:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-16","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":872,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.36944,"AVALU":"U/L","BASE2":2.30918,"BASE":28.92051,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.06027,"PCHG2":219.13712,"CHG":-21.55106,"PCHG":-74.51827,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-03 05:04:34","ADY":960,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-252","SUBJID":"id-252","SITEID":"JPN-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54319,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-16 05:04:34","TRTEDTM":"2023-10-16 23:04:34","TRT01SDTM":"2020-10-16 05:04:34","TRT01EDTM":"2022-10-16 17:04:34","TRT02SDTM":"2022-10-16 17:04:34","TRT02EDTM":"2023-10-16 23:04:34","AP01SDTM":"2020-10-16 05:04:34","AP01EDTM":"2022-10-16 17:04:34","AP02SDTM":"2022-10-16 17:04:34","AP02EDTM":"2023-10-16 23:04:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-16","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2536,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.62025,"AVALU":"mg/L","BASE2":10.62025,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-07-19 05:04:34","ADY":276,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-252","SUBJID":"id-252","SITEID":"JPN-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54319,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-16 05:04:34","TRTEDTM":"2023-10-16 23:04:34","TRT01SDTM":"2020-10-16 05:04:34","TRT01EDTM":"2022-10-16 17:04:34","TRT02SDTM":"2022-10-16 17:04:34","TRT02EDTM":"2023-10-16 23:04:34","AP01SDTM":"2020-10-16 05:04:34","AP01EDTM":"2022-10-16 17:04:34","AP02SDTM":"2022-10-16 17:04:34","AP02EDTM":"2023-10-16 23:04:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-16","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3614,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.90913,"AVALU":"mg/L","BASE2":10.62025,"BASE":9.90913,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.71111,"PCHG2":-6.69584,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-08 05:04:34","ADY":418,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-252","SUBJID":"id-252","SITEID":"JPN-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54319,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-16 05:04:34","TRTEDTM":"2023-10-16 23:04:34","TRT01SDTM":"2020-10-16 05:04:34","TRT01EDTM":"2022-10-16 17:04:34","TRT02SDTM":"2022-10-16 17:04:34","TRT02EDTM":"2023-10-16 23:04:34","AP01SDTM":"2020-10-16 05:04:34","AP01EDTM":"2022-10-16 17:04:34","AP02SDTM":"2022-10-16 17:04:34","AP02EDTM":"2023-10-16 23:04:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-16","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3114,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.84558,"AVALU":"mg/L","BASE2":10.62025,"BASE":9.90913,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.77467,"PCHG2":-16.71023,"CHG":-1.06355,"PCHG":-10.73305,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-07 05:04:34","ADY":538,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-252","SUBJID":"id-252","SITEID":"JPN-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54319,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-16 05:04:34","TRTEDTM":"2023-10-16 23:04:34","TRT01SDTM":"2020-10-16 05:04:34","TRT01EDTM":"2022-10-16 17:04:34","TRT02SDTM":"2022-10-16 17:04:34","TRT02EDTM":"2023-10-16 23:04:34","AP01SDTM":"2020-10-16 05:04:34","AP01EDTM":"2022-10-16 17:04:34","AP02SDTM":"2022-10-16 17:04:34","AP02EDTM":"2023-10-16 23:04:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-16","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4512,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.49972,"AVALU":"mg/L","BASE2":10.62025,"BASE":9.90913,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.12052,"PCHG2":-10.55083,"CHG":-0.40941,"PCHG":-4.13164,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-19 05:04:34","ADY":611,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-252","SUBJID":"id-252","SITEID":"JPN-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54319,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-16 05:04:34","TRTEDTM":"2023-10-16 23:04:34","TRT01SDTM":"2020-10-16 05:04:34","TRT01EDTM":"2022-10-16 17:04:34","TRT02SDTM":"2022-10-16 17:04:34","TRT02EDTM":"2023-10-16 23:04:34","AP01SDTM":"2020-10-16 05:04:34","AP01EDTM":"2022-10-16 17:04:34","AP02SDTM":"2022-10-16 17:04:34","AP02EDTM":"2023-10-16 23:04:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-16","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":324,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.68034,"AVALU":"mg/L","BASE2":10.62025,"BASE":9.90913,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.93991,"PCHG2":-8.85019,"CHG":-0.2288,"PCHG":-2.30895,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-08 05:04:34","ADY":845,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-252","SUBJID":"id-252","SITEID":"JPN-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54319,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-16 05:04:34","TRTEDTM":"2023-10-16 23:04:34","TRT01SDTM":"2020-10-16 05:04:34","TRT01EDTM":"2022-10-16 17:04:34","TRT02SDTM":"2022-10-16 17:04:34","TRT02EDTM":"2023-10-16 23:04:34","AP01SDTM":"2020-10-16 05:04:34","AP01EDTM":"2022-10-16 17:04:34","AP02SDTM":"2022-10-16 17:04:34","AP02EDTM":"2023-10-16 23:04:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-16","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1639,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.11685,"AVALU":"mg/L","BASE2":10.62025,"BASE":9.90913,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.5034,"PCHG2":-14.15596,"CHG":-0.79228,"PCHG":-7.99549,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-09 05:04:34","ADY":846,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-252","SUBJID":"id-252","SITEID":"JPN-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54319,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-16 05:04:34","TRTEDTM":"2023-10-16 23:04:34","TRT01SDTM":"2020-10-16 05:04:34","TRT01EDTM":"2022-10-16 17:04:34","TRT02SDTM":"2022-10-16 17:04:34","TRT02EDTM":"2023-10-16 23:04:34","AP01SDTM":"2020-10-16 05:04:34","AP01EDTM":"2022-10-16 17:04:34","AP02SDTM":"2022-10-16 17:04:34","AP02EDTM":"2023-10-16 23:04:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-16","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5061,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.34974,"AVALU":"mg/L","BASE2":10.62025,"BASE":9.90913,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.27051,"PCHG2":-2.54708,"CHG":0.44061,"PCHG":4.4465,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2023-06-03 05:04:34","ADY":960,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-252","SUBJID":"id-252","SITEID":"JPN-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54319,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-16 05:04:34","TRTEDTM":"2023-10-16 23:04:34","TRT01SDTM":"2020-10-16 05:04:34","TRT01EDTM":"2022-10-16 17:04:34","TRT02SDTM":"2022-10-16 17:04:34","TRT02EDTM":"2023-10-16 23:04:34","AP01SDTM":"2020-10-16 05:04:34","AP01EDTM":"2022-10-16 17:04:34","AP02SDTM":"2022-10-16 17:04:34","AP02EDTM":"2023-10-16 23:04:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-16","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2300,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84746,"AVALU":"g/L","BASE2":2.84746,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-19 05:04:34","ADY":276,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-252","SUBJID":"id-252","SITEID":"JPN-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54319,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-16 05:04:34","TRTEDTM":"2023-10-16 23:04:34","TRT01SDTM":"2020-10-16 05:04:34","TRT01EDTM":"2022-10-16 17:04:34","TRT02SDTM":"2022-10-16 17:04:34","TRT02EDTM":"2023-10-16 23:04:34","AP01SDTM":"2020-10-16 05:04:34","AP01EDTM":"2022-10-16 17:04:34","AP02SDTM":"2022-10-16 17:04:34","AP02EDTM":"2023-10-16 23:04:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-16","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1222,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90733,"AVALU":"g/L","BASE2":2.84746,"BASE":2.90733,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.05987,"PCHG2":2.10258,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-08 05:04:34","ADY":418,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-252","SUBJID":"id-252","SITEID":"JPN-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54319,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-16 05:04:34","TRTEDTM":"2023-10-16 23:04:34","TRT01SDTM":"2020-10-16 05:04:34","TRT01EDTM":"2022-10-16 17:04:34","TRT02SDTM":"2022-10-16 17:04:34","TRT02EDTM":"2023-10-16 23:04:34","AP01SDTM":"2020-10-16 05:04:34","AP01EDTM":"2022-10-16 17:04:34","AP02SDTM":"2022-10-16 17:04:34","AP02EDTM":"2023-10-16 23:04:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-16","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":114,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84379,"AVALU":"g/L","BASE2":2.84746,"BASE":2.90733,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00367,"PCHG2":-0.12896,"CHG":-0.06354,"PCHG":-2.18559,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-07 05:04:34","ADY":538,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-252","SUBJID":"id-252","SITEID":"JPN-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54319,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-16 05:04:34","TRTEDTM":"2023-10-16 23:04:34","TRT01SDTM":"2020-10-16 05:04:34","TRT01EDTM":"2022-10-16 17:04:34","TRT02SDTM":"2022-10-16 17:04:34","TRT02EDTM":"2023-10-16 23:04:34","AP01SDTM":"2020-10-16 05:04:34","AP01EDTM":"2022-10-16 17:04:34","AP02SDTM":"2022-10-16 17:04:34","AP02EDTM":"2023-10-16 23:04:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-16","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5618,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01316,"AVALU":"g/L","BASE2":2.84746,"BASE":2.90733,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1657,"PCHG2":5.81935,"CHG":0.10583,"PCHG":3.64023,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-06-19 05:04:34","ADY":611,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-252","SUBJID":"id-252","SITEID":"JPN-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54319,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-16 05:04:34","TRTEDTM":"2023-10-16 23:04:34","TRT01SDTM":"2020-10-16 05:04:34","TRT01EDTM":"2022-10-16 17:04:34","TRT02SDTM":"2022-10-16 17:04:34","TRT02EDTM":"2023-10-16 23:04:34","AP01SDTM":"2020-10-16 05:04:34","AP01EDTM":"2022-10-16 17:04:34","AP02SDTM":"2022-10-16 17:04:34","AP02EDTM":"2023-10-16 23:04:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-16","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7886,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03122,"AVALU":"g/L","BASE2":2.84746,"BASE":2.90733,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18376,"PCHG2":6.45359,"CHG":0.12389,"PCHG":4.26141,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2023-02-08 05:04:34","ADY":845,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-252","SUBJID":"id-252","SITEID":"JPN-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54319,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-16 05:04:34","TRTEDTM":"2023-10-16 23:04:34","TRT01SDTM":"2020-10-16 05:04:34","TRT01EDTM":"2022-10-16 17:04:34","TRT02SDTM":"2022-10-16 17:04:34","TRT02EDTM":"2023-10-16 23:04:34","AP01SDTM":"2020-10-16 05:04:34","AP01EDTM":"2022-10-16 17:04:34","AP02SDTM":"2022-10-16 17:04:34","AP02EDTM":"2023-10-16 23:04:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-16","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2890,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89669,"AVALU":"g/L","BASE2":2.84746,"BASE":2.90733,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04923,"PCHG2":1.72874,"CHG":-0.01065,"PCHG":-0.36614,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-09 05:04:34","ADY":846,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-252","SUBJID":"id-252","SITEID":"JPN-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54319,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-16 05:04:34","TRTEDTM":"2023-10-16 23:04:34","TRT01SDTM":"2020-10-16 05:04:34","TRT01EDTM":"2022-10-16 17:04:34","TRT02SDTM":"2022-10-16 17:04:34","TRT02EDTM":"2023-10-16 23:04:34","AP01SDTM":"2020-10-16 05:04:34","AP01EDTM":"2022-10-16 17:04:34","AP02SDTM":"2022-10-16 17:04:34","AP02EDTM":"2023-10-16 23:04:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-16","EOSDY":1096,"LSTALVDT":"2023-10-26","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6416,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90008,"AVALU":"g/L","BASE2":2.84746,"BASE":2.90733,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05262,"PCHG2":1.848,"CHG":-0.00725,"PCHG":-0.24935,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-03 05:04:34","ADY":960,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-326","SUBJID":"id-326","SITEID":"JPN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":8.09449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-03 13:10:25","TRT01SDTM":"2019-11-03 13:10:25","AP01SDTM":"2019-11-03 13:10:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1992,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.81606,"AVALU":"U/L","BASE2":2.81606,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2019-12-06 13:10:25","ADY":33,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-326","SUBJID":"id-326","SITEID":"JPN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":8.09449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-03 13:10:25","TRT01SDTM":"2019-11-03 13:10:25","AP01SDTM":"2019-11-03 13:10:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1540,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.04674,"AVALU":"U/L","BASE2":2.81606,"BASE":12.04674,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":9.23068,"PCHG2":327.787,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-23 13:10:25","ADY":172,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-326","SUBJID":"id-326","SITEID":"JPN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":8.09449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-03 13:10:25","TRT01SDTM":"2019-11-03 13:10:25","AP01SDTM":"2019-11-03 13:10:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1066,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.68147,"AVALU":"U/L","BASE2":2.81606,"BASE":12.04674,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.86541,"PCHG2":598.90109,"CHG":7.63473,"PCHG":63.37595,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-24 13:10:25","ADY":234,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-326","SUBJID":"id-326","SITEID":"JPN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":8.09449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-03 13:10:25","TRT01SDTM":"2019-11-03 13:10:25","AP01SDTM":"2019-11-03 13:10:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7002,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.49308,"AVALU":"U/L","BASE2":2.81606,"BASE":12.04674,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.67702,"PCHG2":130.57333,"CHG":-5.55365,"PCHG":-46.1009,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-09-19 13:10:25","ADY":321,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-326","SUBJID":"id-326","SITEID":"JPN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":8.09449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-03 13:10:25","TRT01SDTM":"2019-11-03 13:10:25","AP01SDTM":"2019-11-03 13:10:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4940,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":35.00284,"AVALU":"U/L","BASE2":2.81606,"BASE":12.04674,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":32.18678,"PCHG2":1142.97235,"CHG":22.9561,"PCHG":190.5587,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-18 13:10:25","ADY":411,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-326","SUBJID":"id-326","SITEID":"JPN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":8.09449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-03 13:10:25","TRT01SDTM":"2019-11-03 13:10:25","AP01SDTM":"2019-11-03 13:10:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8298,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.35592,"AVALU":"U/L","BASE2":2.81606,"BASE":12.04674,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":17.53986,"PCHG2":622.85117,"CHG":8.30918,"PCHG":68.97455,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-25 13:10:25","ADY":449,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-326","SUBJID":"id-326","SITEID":"JPN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":8.09449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-03 13:10:25","TRT01SDTM":"2019-11-03 13:10:25","AP01SDTM":"2019-11-03 13:10:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":17,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.21161,"AVALU":"U/L","BASE2":2.81606,"BASE":12.04674,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.39555,"PCHG2":546.70537,"CHG":6.16487,"PCHG":51.17462,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-29 13:10:25","ADY":726,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-326","SUBJID":"id-326","SITEID":"JPN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":8.09449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-03 13:10:25","TRT01SDTM":"2019-11-03 13:10:25","AP01SDTM":"2019-11-03 13:10:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":624,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.53595,"AVALU":"mg/L","BASE2":9.53595,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-06 13:10:25","ADY":33,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-326","SUBJID":"id-326","SITEID":"JPN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":8.09449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-03 13:10:25","TRT01SDTM":"2019-11-03 13:10:25","AP01SDTM":"2019-11-03 13:10:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3945,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.66235,"AVALU":"mg/L","BASE2":9.53595,"BASE":9.66235,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.12639,"PCHG2":1.32546,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-23 13:10:25","ADY":172,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-326","SUBJID":"id-326","SITEID":"JPN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":8.09449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-03 13:10:25","TRT01SDTM":"2019-11-03 13:10:25","AP01SDTM":"2019-11-03 13:10:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3490,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.92713,"AVALU":"mg/L","BASE2":9.53595,"BASE":9.66235,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.60882,"PCHG2":-6.38448,"CHG":-0.73522,"PCHG":-7.60908,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-24 13:10:25","ADY":234,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-326","SUBJID":"id-326","SITEID":"JPN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":8.09449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-03 13:10:25","TRT01SDTM":"2019-11-03 13:10:25","AP01SDTM":"2019-11-03 13:10:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5968,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.66899,"AVALU":"mg/L","BASE2":9.53595,"BASE":9.66235,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.86696,"PCHG2":-19.57812,"CHG":-1.99335,"PCHG":-20.63013,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-09-19 13:10:25","ADY":321,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-326","SUBJID":"id-326","SITEID":"JPN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":8.09449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-03 13:10:25","TRT01SDTM":"2019-11-03 13:10:25","AP01SDTM":"2019-11-03 13:10:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3578,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.04507,"AVALU":"mg/L","BASE2":9.53595,"BASE":9.66235,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.49088,"PCHG2":-5.14771,"CHG":-0.61728,"PCHG":-6.38849,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-18 13:10:25","ADY":411,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-326","SUBJID":"id-326","SITEID":"JPN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":8.09449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-03 13:10:25","TRT01SDTM":"2019-11-03 13:10:25","AP01SDTM":"2019-11-03 13:10:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6215,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.23417,"AVALU":"mg/L","BASE2":9.53595,"BASE":9.66235,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.30178,"PCHG2":-3.16467,"CHG":-0.42818,"PCHG":-4.43139,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-25 13:10:25","ADY":449,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-326","SUBJID":"id-326","SITEID":"JPN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":8.09449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-03 13:10:25","TRT01SDTM":"2019-11-03 13:10:25","AP01SDTM":"2019-11-03 13:10:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1991,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.70394,"AVALU":"mg/L","BASE2":9.53595,"BASE":9.66235,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.16798,"PCHG2":22.73484,"CHG":2.04159,"PCHG":21.12933,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-10-29 13:10:25","ADY":726,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-326","SUBJID":"id-326","SITEID":"JPN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":8.09449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-03 13:10:25","TRT01SDTM":"2019-11-03 13:10:25","AP01SDTM":"2019-11-03 13:10:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6236,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9003,"AVALU":"g/L","BASE2":2.9003,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-06 13:10:25","ADY":33,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-326","SUBJID":"id-326","SITEID":"JPN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":8.09449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-03 13:10:25","TRT01SDTM":"2019-11-03 13:10:25","AP01SDTM":"2019-11-03 13:10:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":577,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89011,"AVALU":"g/L","BASE2":2.9003,"BASE":2.89011,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.0102,"PCHG2":-0.35155,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-23 13:10:25","ADY":172,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-326","SUBJID":"id-326","SITEID":"JPN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":8.09449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-03 13:10:25","TRT01SDTM":"2019-11-03 13:10:25","AP01SDTM":"2019-11-03 13:10:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2220,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87584,"AVALU":"g/L","BASE2":2.9003,"BASE":2.89011,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02446,"PCHG2":-0.84325,"CHG":-0.01426,"PCHG":-0.49343,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-24 13:10:25","ADY":234,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-326","SUBJID":"id-326","SITEID":"JPN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":8.09449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-03 13:10:25","TRT01SDTM":"2019-11-03 13:10:25","AP01SDTM":"2019-11-03 13:10:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4162,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78553,"AVALU":"g/L","BASE2":2.9003,"BASE":2.89011,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11477,"PCHG2":-3.95713,"CHG":-0.10457,"PCHG":-3.6183,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-19 13:10:25","ADY":321,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-326","SUBJID":"id-326","SITEID":"JPN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":8.09449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-03 13:10:25","TRT01SDTM":"2019-11-03 13:10:25","AP01SDTM":"2019-11-03 13:10:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4656,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8877,"AVALU":"g/L","BASE2":2.9003,"BASE":2.89011,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01261,"PCHG2":-0.43461,"CHG":-0.00241,"PCHG":-0.08336,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-18 13:10:25","ADY":411,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-326","SUBJID":"id-326","SITEID":"JPN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":8.09449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-03 13:10:25","TRT01SDTM":"2019-11-03 13:10:25","AP01SDTM":"2019-11-03 13:10:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3162,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76022,"AVALU":"g/L","BASE2":2.9003,"BASE":2.89011,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14009,"PCHG2":-4.83004,"CHG":-0.12989,"PCHG":-4.49429,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-25 13:10:25","ADY":449,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-5-id-326","SUBJID":"id-326","SITEID":"JPN-5","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-5","INVNAM":"Dr. JPN-5 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":8.09449,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-03","TRTSDTM":"2019-11-03 13:10:25","TRT01SDTM":"2019-11-03 13:10:25","AP01SDTM":"2019-11-03 13:10:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3393,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92823,"AVALU":"g/L","BASE2":2.9003,"BASE":2.89011,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02792,"PCHG2":0.96282,"CHG":0.03812,"PCHG":1.319,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-29 13:10:25","ADY":726,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-6-id-260","SUBJID":"id-260","SITEID":"JPN-6","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-6","INVNAM":"Dr. JPN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.71335,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-06 23:20:36","TRTEDTM":"2024-01-07 17:20:36","TRT01SDTM":"2021-01-06 23:20:36","TRT01EDTM":"2023-01-07 11:20:36","TRT02SDTM":"2023-01-07 11:20:36","TRT02EDTM":"2024-01-07 17:20:36","AP01SDTM":"2021-01-06 23:20:36","AP01EDTM":"2023-01-07 11:20:36","AP02SDTM":"2023-01-07 11:20:36","AP02EDTM":"2024-01-07 17:20:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1426,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.36089,"AVALU":"U/L","BASE2":16.36089,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-08 23:20:36","ADY":61,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-6-id-260","SUBJID":"id-260","SITEID":"JPN-6","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-6","INVNAM":"Dr. JPN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.71335,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-06 23:20:36","TRTEDTM":"2024-01-07 17:20:36","TRT01SDTM":"2021-01-06 23:20:36","TRT01EDTM":"2023-01-07 11:20:36","TRT02SDTM":"2023-01-07 11:20:36","TRT02EDTM":"2024-01-07 17:20:36","AP01SDTM":"2021-01-06 23:20:36","AP01EDTM":"2023-01-07 11:20:36","AP02SDTM":"2023-01-07 11:20:36","AP02EDTM":"2024-01-07 17:20:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6810,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.46895,"AVALU":"U/L","BASE2":16.36089,"BASE":15.46895,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.89194,"PCHG2":-5.45167,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-22 23:20:36","ADY":75,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-6-id-260","SUBJID":"id-260","SITEID":"JPN-6","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-6","INVNAM":"Dr. JPN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.71335,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-06 23:20:36","TRTEDTM":"2024-01-07 17:20:36","TRT01SDTM":"2021-01-06 23:20:36","TRT01EDTM":"2023-01-07 11:20:36","TRT02SDTM":"2023-01-07 11:20:36","TRT02EDTM":"2024-01-07 17:20:36","AP01SDTM":"2021-01-06 23:20:36","AP01EDTM":"2023-01-07 11:20:36","AP02SDTM":"2023-01-07 11:20:36","AP02EDTM":"2024-01-07 17:20:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4031,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.26598,"AVALU":"U/L","BASE2":16.36089,"BASE":15.46895,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.90509,"PCHG2":91.10197,"CHG":15.79703,"PCHG":102.12093,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-24 23:20:36","ADY":77,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-6-id-260","SUBJID":"id-260","SITEID":"JPN-6","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-6","INVNAM":"Dr. JPN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.71335,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-06 23:20:36","TRTEDTM":"2024-01-07 17:20:36","TRT01SDTM":"2021-01-06 23:20:36","TRT01EDTM":"2023-01-07 11:20:36","TRT02SDTM":"2023-01-07 11:20:36","TRT02EDTM":"2024-01-07 17:20:36","AP01SDTM":"2021-01-06 23:20:36","AP01EDTM":"2023-01-07 11:20:36","AP02SDTM":"2023-01-07 11:20:36","AP02EDTM":"2024-01-07 17:20:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":684,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.90843,"AVALU":"U/L","BASE2":16.36089,"BASE":15.46895,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.45246,"PCHG2":-51.66261,"CHG":-7.56052,"PCHG":-48.87547,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-25 23:20:36","ADY":139,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-6-id-260","SUBJID":"id-260","SITEID":"JPN-6","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-6","INVNAM":"Dr. JPN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.71335,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-06 23:20:36","TRTEDTM":"2024-01-07 17:20:36","TRT01SDTM":"2021-01-06 23:20:36","TRT01EDTM":"2023-01-07 11:20:36","TRT02SDTM":"2023-01-07 11:20:36","TRT02EDTM":"2024-01-07 17:20:36","AP01SDTM":"2021-01-06 23:20:36","AP01EDTM":"2023-01-07 11:20:36","AP02SDTM":"2023-01-07 11:20:36","AP02EDTM":"2024-01-07 17:20:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2141,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.98373,"AVALU":"U/L","BASE2":16.36089,"BASE":15.46895,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.62284,"PCHG2":46.59184,"CHG":8.51478,"PCHG":55.04434,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-17 23:20:36","ADY":407,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-6-id-260","SUBJID":"id-260","SITEID":"JPN-6","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-6","INVNAM":"Dr. JPN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.71335,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-06 23:20:36","TRTEDTM":"2024-01-07 17:20:36","TRT01SDTM":"2021-01-06 23:20:36","TRT01EDTM":"2023-01-07 11:20:36","TRT02SDTM":"2023-01-07 11:20:36","TRT02EDTM":"2024-01-07 17:20:36","AP01SDTM":"2021-01-06 23:20:36","AP01EDTM":"2023-01-07 11:20:36","AP02SDTM":"2023-01-07 11:20:36","AP02EDTM":"2024-01-07 17:20:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2545,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.43355,"AVALU":"U/L","BASE2":16.36089,"BASE":15.46895,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.92734,"PCHG2":-60.67729,"CHG":-9.0354,"PCHG":-58.40993,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2022-05-22 23:20:36","ADY":501,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-6-id-260","SUBJID":"id-260","SITEID":"JPN-6","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-6","INVNAM":"Dr. JPN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.71335,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-06 23:20:36","TRTEDTM":"2024-01-07 17:20:36","TRT01SDTM":"2021-01-06 23:20:36","TRT01EDTM":"2023-01-07 11:20:36","TRT02SDTM":"2023-01-07 11:20:36","TRT02EDTM":"2024-01-07 17:20:36","AP01SDTM":"2021-01-06 23:20:36","AP01EDTM":"2023-01-07 11:20:36","AP02SDTM":"2023-01-07 11:20:36","AP02EDTM":"2024-01-07 17:20:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7880,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.69392,"AVALU":"U/L","BASE2":16.36089,"BASE":15.46895,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.66697,"PCHG2":-83.53439,"CHG":-12.77503,"PCHG":-82.58498,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2023-10-30 23:20:36","ADY":1027,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-6-id-260","SUBJID":"id-260","SITEID":"JPN-6","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-6","INVNAM":"Dr. JPN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.71335,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-06 23:20:36","TRTEDTM":"2024-01-07 17:20:36","TRT01SDTM":"2021-01-06 23:20:36","TRT01EDTM":"2023-01-07 11:20:36","TRT02SDTM":"2023-01-07 11:20:36","TRT02EDTM":"2024-01-07 17:20:36","AP01SDTM":"2021-01-06 23:20:36","AP01EDTM":"2023-01-07 11:20:36","AP02SDTM":"2023-01-07 11:20:36","AP02EDTM":"2024-01-07 17:20:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7597,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.98554,"AVALU":"mg/L","BASE2":8.98554,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-08 23:20:36","ADY":61,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-6-id-260","SUBJID":"id-260","SITEID":"JPN-6","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-6","INVNAM":"Dr. JPN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.71335,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-06 23:20:36","TRTEDTM":"2024-01-07 17:20:36","TRT01SDTM":"2021-01-06 23:20:36","TRT01EDTM":"2023-01-07 11:20:36","TRT02SDTM":"2023-01-07 11:20:36","TRT02EDTM":"2024-01-07 17:20:36","AP01SDTM":"2021-01-06 23:20:36","AP01EDTM":"2023-01-07 11:20:36","AP02SDTM":"2023-01-07 11:20:36","AP02EDTM":"2024-01-07 17:20:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1915,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.83473,"AVALU":"mg/L","BASE2":8.98554,"BASE":9.83473,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.84919,"PCHG2":9.45058,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-22 23:20:36","ADY":75,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-6-id-260","SUBJID":"id-260","SITEID":"JPN-6","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-6","INVNAM":"Dr. JPN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.71335,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-06 23:20:36","TRTEDTM":"2024-01-07 17:20:36","TRT01SDTM":"2021-01-06 23:20:36","TRT01EDTM":"2023-01-07 11:20:36","TRT02SDTM":"2023-01-07 11:20:36","TRT02EDTM":"2024-01-07 17:20:36","AP01SDTM":"2021-01-06 23:20:36","AP01EDTM":"2023-01-07 11:20:36","AP02SDTM":"2023-01-07 11:20:36","AP02EDTM":"2024-01-07 17:20:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3640,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.78768,"AVALU":"mg/L","BASE2":8.98554,"BASE":9.83473,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19787,"PCHG2":-2.20205,"CHG":-1.04705,"PCHG":-10.64647,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-24 23:20:36","ADY":77,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-6-id-260","SUBJID":"id-260","SITEID":"JPN-6","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-6","INVNAM":"Dr. JPN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.71335,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-06 23:20:36","TRTEDTM":"2024-01-07 17:20:36","TRT01SDTM":"2021-01-06 23:20:36","TRT01EDTM":"2023-01-07 11:20:36","TRT02SDTM":"2023-01-07 11:20:36","TRT02EDTM":"2024-01-07 17:20:36","AP01SDTM":"2021-01-06 23:20:36","AP01EDTM":"2023-01-07 11:20:36","AP02SDTM":"2023-01-07 11:20:36","AP02EDTM":"2024-01-07 17:20:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7715,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.85427,"AVALU":"mg/L","BASE2":8.98554,"BASE":9.83473,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.86873,"PCHG2":20.79702,"CHG":1.01954,"PCHG":10.36673,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-05-25 23:20:36","ADY":139,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-6-id-260","SUBJID":"id-260","SITEID":"JPN-6","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-6","INVNAM":"Dr. JPN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.71335,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-06 23:20:36","TRTEDTM":"2024-01-07 17:20:36","TRT01SDTM":"2021-01-06 23:20:36","TRT01EDTM":"2023-01-07 11:20:36","TRT02SDTM":"2023-01-07 11:20:36","TRT02EDTM":"2024-01-07 17:20:36","AP01SDTM":"2021-01-06 23:20:36","AP01EDTM":"2023-01-07 11:20:36","AP02SDTM":"2023-01-07 11:20:36","AP02EDTM":"2024-01-07 17:20:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4282,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.67988,"AVALU":"mg/L","BASE2":8.98554,"BASE":9.83473,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.69434,"PCHG2":7.72727,"CHG":-0.15485,"PCHG":-1.5745,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-17 23:20:36","ADY":407,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-6-id-260","SUBJID":"id-260","SITEID":"JPN-6","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-6","INVNAM":"Dr. JPN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.71335,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-06 23:20:36","TRTEDTM":"2024-01-07 17:20:36","TRT01SDTM":"2021-01-06 23:20:36","TRT01EDTM":"2023-01-07 11:20:36","TRT02SDTM":"2023-01-07 11:20:36","TRT02EDTM":"2024-01-07 17:20:36","AP01SDTM":"2021-01-06 23:20:36","AP01EDTM":"2023-01-07 11:20:36","AP02SDTM":"2023-01-07 11:20:36","AP02EDTM":"2024-01-07 17:20:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5322,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.14708,"AVALU":"mg/L","BASE2":8.98554,"BASE":9.83473,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16153,"PCHG2":1.79771,"CHG":-0.68765,"PCHG":-6.99207,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-22 23:20:36","ADY":501,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-6-id-260","SUBJID":"id-260","SITEID":"JPN-6","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-6","INVNAM":"Dr. JPN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.71335,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-06 23:20:36","TRTEDTM":"2024-01-07 17:20:36","TRT01SDTM":"2021-01-06 23:20:36","TRT01EDTM":"2023-01-07 11:20:36","TRT02SDTM":"2023-01-07 11:20:36","TRT02EDTM":"2024-01-07 17:20:36","AP01SDTM":"2021-01-06 23:20:36","AP01EDTM":"2023-01-07 11:20:36","AP02SDTM":"2023-01-07 11:20:36","AP02EDTM":"2024-01-07 17:20:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1741,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.75608,"AVALU":"mg/L","BASE2":8.98554,"BASE":9.83473,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.77054,"PCHG2":8.5753,"CHG":-0.07865,"PCHG":-0.7997,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-10-30 23:20:36","ADY":1027,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-6-id-260","SUBJID":"id-260","SITEID":"JPN-6","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-6","INVNAM":"Dr. JPN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.71335,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-06 23:20:36","TRTEDTM":"2024-01-07 17:20:36","TRT01SDTM":"2021-01-06 23:20:36","TRT01EDTM":"2023-01-07 11:20:36","TRT02SDTM":"2023-01-07 11:20:36","TRT02EDTM":"2024-01-07 17:20:36","AP01SDTM":"2021-01-06 23:20:36","AP01EDTM":"2023-01-07 11:20:36","AP02SDTM":"2023-01-07 11:20:36","AP02EDTM":"2024-01-07 17:20:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":260,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95447,"AVALU":"g/L","BASE2":2.95447,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-08 23:20:36","ADY":61,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-6-id-260","SUBJID":"id-260","SITEID":"JPN-6","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-6","INVNAM":"Dr. JPN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.71335,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-06 23:20:36","TRTEDTM":"2024-01-07 17:20:36","TRT01SDTM":"2021-01-06 23:20:36","TRT01EDTM":"2023-01-07 11:20:36","TRT02SDTM":"2023-01-07 11:20:36","TRT02EDTM":"2024-01-07 17:20:36","AP01SDTM":"2021-01-06 23:20:36","AP01EDTM":"2023-01-07 11:20:36","AP02SDTM":"2023-01-07 11:20:36","AP02EDTM":"2024-01-07 17:20:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1011,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89806,"AVALU":"g/L","BASE2":2.95447,"BASE":2.89806,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.05642,"PCHG2":-1.90954,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-22 23:20:36","ADY":75,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-6-id-260","SUBJID":"id-260","SITEID":"JPN-6","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-6","INVNAM":"Dr. JPN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.71335,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-06 23:20:36","TRTEDTM":"2024-01-07 17:20:36","TRT01SDTM":"2021-01-06 23:20:36","TRT01EDTM":"2023-01-07 11:20:36","TRT02SDTM":"2023-01-07 11:20:36","TRT02EDTM":"2024-01-07 17:20:36","AP01SDTM":"2021-01-06 23:20:36","AP01EDTM":"2023-01-07 11:20:36","AP02SDTM":"2023-01-07 11:20:36","AP02EDTM":"2024-01-07 17:20:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1132,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.14852,"AVALU":"g/L","BASE2":2.95447,"BASE":2.89806,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.19404,"PCHG2":6.5678,"CHG":0.25046,"PCHG":8.64237,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-03-24 23:20:36","ADY":77,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-6-id-260","SUBJID":"id-260","SITEID":"JPN-6","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-6","INVNAM":"Dr. JPN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.71335,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-06 23:20:36","TRTEDTM":"2024-01-07 17:20:36","TRT01SDTM":"2021-01-06 23:20:36","TRT01EDTM":"2023-01-07 11:20:36","TRT02SDTM":"2023-01-07 11:20:36","TRT02EDTM":"2024-01-07 17:20:36","AP01SDTM":"2021-01-06 23:20:36","AP01EDTM":"2023-01-07 11:20:36","AP02SDTM":"2023-01-07 11:20:36","AP02EDTM":"2024-01-07 17:20:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1944,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82792,"AVALU":"g/L","BASE2":2.95447,"BASE":2.89806,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12656,"PCHG2":-4.28356,"CHG":-0.07014,"PCHG":-2.42023,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-25 23:20:36","ADY":139,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-6-id-260","SUBJID":"id-260","SITEID":"JPN-6","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-6","INVNAM":"Dr. JPN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.71335,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-06 23:20:36","TRTEDTM":"2024-01-07 17:20:36","TRT01SDTM":"2021-01-06 23:20:36","TRT01EDTM":"2023-01-07 11:20:36","TRT02SDTM":"2023-01-07 11:20:36","TRT02EDTM":"2024-01-07 17:20:36","AP01SDTM":"2021-01-06 23:20:36","AP01EDTM":"2023-01-07 11:20:36","AP02SDTM":"2023-01-07 11:20:36","AP02EDTM":"2024-01-07 17:20:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1801,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88052,"AVALU":"g/L","BASE2":2.95447,"BASE":2.89806,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07395,"PCHG2":-2.50302,"CHG":-0.01753,"PCHG":-0.60503,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-17 23:20:36","ADY":407,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-6-id-260","SUBJID":"id-260","SITEID":"JPN-6","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-6","INVNAM":"Dr. JPN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.71335,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-06 23:20:36","TRTEDTM":"2024-01-07 17:20:36","TRT01SDTM":"2021-01-06 23:20:36","TRT01EDTM":"2023-01-07 11:20:36","TRT02SDTM":"2023-01-07 11:20:36","TRT02EDTM":"2024-01-07 17:20:36","AP01SDTM":"2021-01-06 23:20:36","AP01EDTM":"2023-01-07 11:20:36","AP02SDTM":"2023-01-07 11:20:36","AP02EDTM":"2024-01-07 17:20:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3913,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9148,"AVALU":"g/L","BASE2":2.95447,"BASE":2.89806,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03967,"PCHG2":-1.34275,"CHG":0.01675,"PCHG":0.57783,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-22 23:20:36","ADY":501,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-JPN-6-id-260","SUBJID":"id-260","SITEID":"JPN-6","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"JPN","DTHFL":"N","INVID":"INV ID JPN-6","INVNAM":"Dr. JPN-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":2.71335,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-03","TRTSDTM":"2021-01-06 23:20:36","TRTEDTM":"2024-01-07 17:20:36","TRT01SDTM":"2021-01-06 23:20:36","TRT01EDTM":"2023-01-07 11:20:36","TRT02SDTM":"2023-01-07 11:20:36","TRT02EDTM":"2024-01-07 17:20:36","AP01SDTM":"2021-01-06 23:20:36","AP01EDTM":"2023-01-07 11:20:36","AP02SDTM":"2023-01-07 11:20:36","AP02EDTM":"2024-01-07 17:20:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-07","EOSDY":1096,"LSTALVDT":"2024-01-17","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2643,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89367,"AVALU":"g/L","BASE2":2.95447,"BASE":2.89806,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0608,"PCHG2":-2.05794,"CHG":-0.00438,"PCHG":-0.15129,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-10-30 23:20:36","ADY":1027,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-172","SUBJID":"id-172","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.61988,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-02","TRTSDTM":"2020-03-06 08:29:56","TRTEDTM":"2023-03-07 02:29:56","TRT01SDTM":"2020-03-06 08:29:56","TRT01EDTM":"2022-03-06 20:29:56","TRT02SDTM":"2022-03-06 20:29:56","TRT02EDTM":"2023-03-07 02:29:56","AP01SDTM":"2020-03-06 08:29:56","AP01EDTM":"2022-03-06 20:29:56","AP02SDTM":"2022-03-06 20:29:56","AP02EDTM":"2023-03-07 02:29:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-07","EOSDY":1096,"LSTALVDT":"2023-03-22","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3579,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.99753,"AVALU":"U/L","BASE2":13.99753,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-05 08:29:56","ADY":152,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-172","SUBJID":"id-172","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.61988,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-02","TRTSDTM":"2020-03-06 08:29:56","TRTEDTM":"2023-03-07 02:29:56","TRT01SDTM":"2020-03-06 08:29:56","TRT01EDTM":"2022-03-06 20:29:56","TRT02SDTM":"2022-03-06 20:29:56","TRT02EDTM":"2023-03-07 02:29:56","AP01SDTM":"2020-03-06 08:29:56","AP01EDTM":"2022-03-06 20:29:56","AP02SDTM":"2022-03-06 20:29:56","AP02EDTM":"2023-03-07 02:29:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-07","EOSDY":1096,"LSTALVDT":"2023-03-22","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6801,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.05751,"AVALU":"U/L","BASE2":13.99753,"BASE":13.05751,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.94003,"PCHG2":-6.71566,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-04 08:29:56","ADY":212,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-172","SUBJID":"id-172","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.61988,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-02","TRTSDTM":"2020-03-06 08:29:56","TRTEDTM":"2023-03-07 02:29:56","TRT01SDTM":"2020-03-06 08:29:56","TRT01EDTM":"2022-03-06 20:29:56","TRT02SDTM":"2022-03-06 20:29:56","TRT02EDTM":"2023-03-07 02:29:56","AP01SDTM":"2020-03-06 08:29:56","AP01EDTM":"2022-03-06 20:29:56","AP02SDTM":"2022-03-06 20:29:56","AP02EDTM":"2023-03-07 02:29:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-07","EOSDY":1096,"LSTALVDT":"2023-03-22","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3473,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.83997,"AVALU":"U/L","BASE2":13.99753,"BASE":13.05751,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.84244,"PCHG2":98.89197,"CHG":14.78246,"PCHG":113.21045,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-24 08:29:56","ADY":324,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-172","SUBJID":"id-172","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.61988,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-02","TRTSDTM":"2020-03-06 08:29:56","TRTEDTM":"2023-03-07 02:29:56","TRT01SDTM":"2020-03-06 08:29:56","TRT01EDTM":"2022-03-06 20:29:56","TRT02SDTM":"2022-03-06 20:29:56","TRT02EDTM":"2023-03-07 02:29:56","AP01SDTM":"2020-03-06 08:29:56","AP01EDTM":"2022-03-06 20:29:56","AP02SDTM":"2022-03-06 20:29:56","AP02EDTM":"2023-03-07 02:29:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-07","EOSDY":1096,"LSTALVDT":"2023-03-22","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6812,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.5633,"AVALU":"U/L","BASE2":13.99753,"BASE":13.05751,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.43424,"PCHG2":-31.67869,"CHG":-3.49421,"PCHG":-26.76015,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-01 08:29:56","ADY":332,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-172","SUBJID":"id-172","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.61988,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-02","TRTSDTM":"2020-03-06 08:29:56","TRTEDTM":"2023-03-07 02:29:56","TRT01SDTM":"2020-03-06 08:29:56","TRT01EDTM":"2022-03-06 20:29:56","TRT02SDTM":"2022-03-06 20:29:56","TRT02EDTM":"2023-03-07 02:29:56","AP01SDTM":"2020-03-06 08:29:56","AP01EDTM":"2022-03-06 20:29:56","AP02SDTM":"2022-03-06 20:29:56","AP02EDTM":"2023-03-07 02:29:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-07","EOSDY":1096,"LSTALVDT":"2023-03-22","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5551,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.2048,"AVALU":"U/L","BASE2":13.99753,"BASE":13.05751,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.20727,"PCHG2":15.76897,"CHG":3.14729,"PCHG":24.10333,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-10 08:29:56","ADY":369,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-172","SUBJID":"id-172","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.61988,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-02","TRTSDTM":"2020-03-06 08:29:56","TRTEDTM":"2023-03-07 02:29:56","TRT01SDTM":"2020-03-06 08:29:56","TRT01EDTM":"2022-03-06 20:29:56","TRT02SDTM":"2022-03-06 20:29:56","TRT02EDTM":"2023-03-07 02:29:56","AP01SDTM":"2020-03-06 08:29:56","AP01EDTM":"2022-03-06 20:29:56","AP02SDTM":"2022-03-06 20:29:56","AP02EDTM":"2023-03-07 02:29:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-07","EOSDY":1096,"LSTALVDT":"2023-03-22","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1771,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.37933,"AVALU":"U/L","BASE2":13.99753,"BASE":13.05751,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.6182,"PCHG2":-25.84885,"CHG":-2.67817,"PCHG":-20.51061,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-13 08:29:56","ADY":403,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-172","SUBJID":"id-172","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.61988,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-02","TRTSDTM":"2020-03-06 08:29:56","TRTEDTM":"2023-03-07 02:29:56","TRT01SDTM":"2020-03-06 08:29:56","TRT01EDTM":"2022-03-06 20:29:56","TRT02SDTM":"2022-03-06 20:29:56","TRT02EDTM":"2023-03-07 02:29:56","AP01SDTM":"2020-03-06 08:29:56","AP01EDTM":"2022-03-06 20:29:56","AP02SDTM":"2022-03-06 20:29:56","AP02EDTM":"2023-03-07 02:29:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-07","EOSDY":1096,"LSTALVDT":"2023-03-22","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6628,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.12811,"AVALU":"U/L","BASE2":13.99753,"BASE":13.05751,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.86942,"PCHG2":-63.36417,"CHG":-7.92939,"PCHG":-60.72671,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-08-15 08:29:56","ADY":527,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-172","SUBJID":"id-172","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.61988,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-02","TRTSDTM":"2020-03-06 08:29:56","TRTEDTM":"2023-03-07 02:29:56","TRT01SDTM":"2020-03-06 08:29:56","TRT01EDTM":"2022-03-06 20:29:56","TRT02SDTM":"2022-03-06 20:29:56","TRT02EDTM":"2023-03-07 02:29:56","AP01SDTM":"2020-03-06 08:29:56","AP01EDTM":"2022-03-06 20:29:56","AP02SDTM":"2022-03-06 20:29:56","AP02EDTM":"2023-03-07 02:29:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-07","EOSDY":1096,"LSTALVDT":"2023-03-22","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":307,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.74553,"AVALU":"mg/L","BASE2":8.74553,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-4","ADTM":"2020-08-05 08:29:56","ADY":152,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-172","SUBJID":"id-172","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.61988,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-02","TRTSDTM":"2020-03-06 08:29:56","TRTEDTM":"2023-03-07 02:29:56","TRT01SDTM":"2020-03-06 08:29:56","TRT01EDTM":"2022-03-06 20:29:56","TRT02SDTM":"2022-03-06 20:29:56","TRT02EDTM":"2023-03-07 02:29:56","AP01SDTM":"2020-03-06 08:29:56","AP01EDTM":"2022-03-06 20:29:56","AP02SDTM":"2022-03-06 20:29:56","AP02EDTM":"2023-03-07 02:29:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-07","EOSDY":1096,"LSTALVDT":"2023-03-22","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8115,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.22942,"AVALU":"mg/L","BASE2":8.74553,"BASE":6.22942,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.51611,"PCHG2":-28.77026,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-4","BTOXGR":"-4","ADTM":"2020-10-04 08:29:56","ADY":212,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-172","SUBJID":"id-172","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.61988,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-02","TRTSDTM":"2020-03-06 08:29:56","TRTEDTM":"2023-03-07 02:29:56","TRT01SDTM":"2020-03-06 08:29:56","TRT01EDTM":"2022-03-06 20:29:56","TRT02SDTM":"2022-03-06 20:29:56","TRT02EDTM":"2023-03-07 02:29:56","AP01SDTM":"2020-03-06 08:29:56","AP01EDTM":"2022-03-06 20:29:56","AP02SDTM":"2022-03-06 20:29:56","AP02EDTM":"2023-03-07 02:29:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-07","EOSDY":1096,"LSTALVDT":"2023-03-22","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6641,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.9497,"AVALU":"mg/L","BASE2":8.74553,"BASE":6.22942,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.79582,"PCHG2":-9.09978,"CHG":1.72029,"PCHG":27.61555,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-2","BTOXGR":"-4","ADTM":"2021-01-24 08:29:56","ADY":324,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-172","SUBJID":"id-172","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.61988,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-02","TRTSDTM":"2020-03-06 08:29:56","TRTEDTM":"2023-03-07 02:29:56","TRT01SDTM":"2020-03-06 08:29:56","TRT01EDTM":"2022-03-06 20:29:56","TRT02SDTM":"2022-03-06 20:29:56","TRT02EDTM":"2023-03-07 02:29:56","AP01SDTM":"2020-03-06 08:29:56","AP01EDTM":"2022-03-06 20:29:56","AP02SDTM":"2022-03-06 20:29:56","AP02EDTM":"2023-03-07 02:29:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-07","EOSDY":1096,"LSTALVDT":"2023-03-22","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7247,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.73887,"AVALU":"mg/L","BASE2":8.74553,"BASE":6.22942,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00666,"PCHG2":-0.07617,"CHG":2.50945,"PCHG":40.28387,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-02-01 08:29:56","ADY":332,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-172","SUBJID":"id-172","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.61988,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-02","TRTSDTM":"2020-03-06 08:29:56","TRTEDTM":"2023-03-07 02:29:56","TRT01SDTM":"2020-03-06 08:29:56","TRT01EDTM":"2022-03-06 20:29:56","TRT02SDTM":"2022-03-06 20:29:56","TRT02EDTM":"2023-03-07 02:29:56","AP01SDTM":"2020-03-06 08:29:56","AP01EDTM":"2022-03-06 20:29:56","AP02SDTM":"2022-03-06 20:29:56","AP02EDTM":"2023-03-07 02:29:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-07","EOSDY":1096,"LSTALVDT":"2023-03-22","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1472,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.32703,"AVALU":"mg/L","BASE2":8.74553,"BASE":6.22942,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.41849,"PCHG2":-4.78524,"CHG":2.09762,"PCHG":33.67276,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-03-10 08:29:56","ADY":369,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-172","SUBJID":"id-172","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.61988,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-02","TRTSDTM":"2020-03-06 08:29:56","TRTEDTM":"2023-03-07 02:29:56","TRT01SDTM":"2020-03-06 08:29:56","TRT01EDTM":"2022-03-06 20:29:56","TRT02SDTM":"2022-03-06 20:29:56","TRT02EDTM":"2023-03-07 02:29:56","AP01SDTM":"2020-03-06 08:29:56","AP01EDTM":"2022-03-06 20:29:56","AP02SDTM":"2022-03-06 20:29:56","AP02EDTM":"2023-03-07 02:29:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-07","EOSDY":1096,"LSTALVDT":"2023-03-22","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4356,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.93873,"AVALU":"mg/L","BASE2":8.74553,"BASE":6.22942,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.1932,"PCHG2":13.64352,"CHG":3.70931,"PCHG":59.54505,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-04-13 08:29:56","ADY":403,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-172","SUBJID":"id-172","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.61988,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-02","TRTSDTM":"2020-03-06 08:29:56","TRTEDTM":"2023-03-07 02:29:56","TRT01SDTM":"2020-03-06 08:29:56","TRT01EDTM":"2022-03-06 20:29:56","TRT02SDTM":"2022-03-06 20:29:56","TRT02EDTM":"2023-03-07 02:29:56","AP01SDTM":"2020-03-06 08:29:56","AP01EDTM":"2022-03-06 20:29:56","AP02SDTM":"2022-03-06 20:29:56","AP02EDTM":"2023-03-07 02:29:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-07","EOSDY":1096,"LSTALVDT":"2023-03-22","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6760,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.26511,"AVALU":"mg/L","BASE2":8.74553,"BASE":6.22942,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.48042,"PCHG2":-5.49328,"CHG":2.0357,"PCHG":32.67874,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-08-15 08:29:56","ADY":527,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-172","SUBJID":"id-172","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.61988,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-02","TRTSDTM":"2020-03-06 08:29:56","TRTEDTM":"2023-03-07 02:29:56","TRT01SDTM":"2020-03-06 08:29:56","TRT01EDTM":"2022-03-06 20:29:56","TRT02SDTM":"2022-03-06 20:29:56","TRT02EDTM":"2023-03-07 02:29:56","AP01SDTM":"2020-03-06 08:29:56","AP01EDTM":"2022-03-06 20:29:56","AP02SDTM":"2022-03-06 20:29:56","AP02EDTM":"2023-03-07 02:29:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-07","EOSDY":1096,"LSTALVDT":"2023-03-22","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5373,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94909,"AVALU":"g/L","BASE2":2.94909,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-05 08:29:56","ADY":152,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-172","SUBJID":"id-172","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.61988,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-02","TRTSDTM":"2020-03-06 08:29:56","TRTEDTM":"2023-03-07 02:29:56","TRT01SDTM":"2020-03-06 08:29:56","TRT01EDTM":"2022-03-06 20:29:56","TRT02SDTM":"2022-03-06 20:29:56","TRT02EDTM":"2023-03-07 02:29:56","AP01SDTM":"2020-03-06 08:29:56","AP01EDTM":"2022-03-06 20:29:56","AP02SDTM":"2022-03-06 20:29:56","AP02EDTM":"2023-03-07 02:29:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-07","EOSDY":1096,"LSTALVDT":"2023-03-22","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8276,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84711,"AVALU":"g/L","BASE2":2.94909,"BASE":2.84711,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.10198,"PCHG2":-3.45805,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-04 08:29:56","ADY":212,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-172","SUBJID":"id-172","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.61988,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-02","TRTSDTM":"2020-03-06 08:29:56","TRTEDTM":"2023-03-07 02:29:56","TRT01SDTM":"2020-03-06 08:29:56","TRT01EDTM":"2022-03-06 20:29:56","TRT02SDTM":"2022-03-06 20:29:56","TRT02EDTM":"2023-03-07 02:29:56","AP01SDTM":"2020-03-06 08:29:56","AP01EDTM":"2022-03-06 20:29:56","AP02SDTM":"2022-03-06 20:29:56","AP02EDTM":"2023-03-07 02:29:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-07","EOSDY":1096,"LSTALVDT":"2023-03-22","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4471,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86026,"AVALU":"g/L","BASE2":2.94909,"BASE":2.84711,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08883,"PCHG2":-3.0121,"CHG":0.01315,"PCHG":0.46192,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-24 08:29:56","ADY":324,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-172","SUBJID":"id-172","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.61988,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-02","TRTSDTM":"2020-03-06 08:29:56","TRTEDTM":"2023-03-07 02:29:56","TRT01SDTM":"2020-03-06 08:29:56","TRT01EDTM":"2022-03-06 20:29:56","TRT02SDTM":"2022-03-06 20:29:56","TRT02EDTM":"2023-03-07 02:29:56","AP01SDTM":"2020-03-06 08:29:56","AP01EDTM":"2022-03-06 20:29:56","AP02SDTM":"2022-03-06 20:29:56","AP02EDTM":"2023-03-07 02:29:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-07","EOSDY":1096,"LSTALVDT":"2023-03-22","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":652,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.06839,"AVALU":"g/L","BASE2":2.94909,"BASE":2.84711,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1193,"PCHG2":4.04538,"CHG":0.22128,"PCHG":7.7722,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-02-01 08:29:56","ADY":332,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-172","SUBJID":"id-172","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.61988,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-02","TRTSDTM":"2020-03-06 08:29:56","TRTEDTM":"2023-03-07 02:29:56","TRT01SDTM":"2020-03-06 08:29:56","TRT01EDTM":"2022-03-06 20:29:56","TRT02SDTM":"2022-03-06 20:29:56","TRT02EDTM":"2023-03-07 02:29:56","AP01SDTM":"2020-03-06 08:29:56","AP01EDTM":"2022-03-06 20:29:56","AP02SDTM":"2022-03-06 20:29:56","AP02EDTM":"2023-03-07 02:29:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-07","EOSDY":1096,"LSTALVDT":"2023-03-22","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6907,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02936,"AVALU":"g/L","BASE2":2.94909,"BASE":2.84711,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08026,"PCHG2":2.72164,"CHG":0.18224,"PCHG":6.40104,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-03-10 08:29:56","ADY":369,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-172","SUBJID":"id-172","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.61988,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-02","TRTSDTM":"2020-03-06 08:29:56","TRTEDTM":"2023-03-07 02:29:56","TRT01SDTM":"2020-03-06 08:29:56","TRT01EDTM":"2022-03-06 20:29:56","TRT02SDTM":"2022-03-06 20:29:56","TRT02EDTM":"2023-03-07 02:29:56","AP01SDTM":"2020-03-06 08:29:56","AP01EDTM":"2022-03-06 20:29:56","AP02SDTM":"2022-03-06 20:29:56","AP02EDTM":"2023-03-07 02:29:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-07","EOSDY":1096,"LSTALVDT":"2023-03-22","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6174,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77915,"AVALU":"g/L","BASE2":2.94909,"BASE":2.84711,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16994,"PCHG2":-5.76244,"CHG":-0.06796,"PCHG":-2.38693,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-13 08:29:56","ADY":403,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-172","SUBJID":"id-172","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.61988,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-02","TRTSDTM":"2020-03-06 08:29:56","TRTEDTM":"2023-03-07 02:29:56","TRT01SDTM":"2020-03-06 08:29:56","TRT01EDTM":"2022-03-06 20:29:56","TRT02SDTM":"2022-03-06 20:29:56","TRT02EDTM":"2023-03-07 02:29:56","AP01SDTM":"2020-03-06 08:29:56","AP01EDTM":"2022-03-06 20:29:56","AP02SDTM":"2022-03-06 20:29:56","AP02EDTM":"2023-03-07 02:29:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-07","EOSDY":1096,"LSTALVDT":"2023-03-22","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3767,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92353,"AVALU":"g/L","BASE2":2.94909,"BASE":2.84711,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02557,"PCHG2":-0.86694,"CHG":0.07641,"PCHG":2.68392,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-15 08:29:56","ADY":527,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-198","SUBJID":"id-198","SITEID":"NGA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":8.96,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-26 17:34:20","TRT01SDTM":"2019-12-26 17:34:20","AP01SDTM":"2019-12-26 17:34:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":131,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.58483,"AVALU":"U/L","BASE2":28.58483,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-4","ADTM":"2020-04-19 17:34:20","ADY":115,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-198","SUBJID":"id-198","SITEID":"NGA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":8.96,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-26 17:34:20","TRT01SDTM":"2019-12-26 17:34:20","AP01SDTM":"2019-12-26 17:34:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3033,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.65778,"AVALU":"U/L","BASE2":28.58483,"BASE":3.65778,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-24.92705,"PCHG2":-87.20376,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-4","BTOXGR":"-4","ADTM":"2020-04-25 17:34:20","ADY":121,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-198","SUBJID":"id-198","SITEID":"NGA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":8.96,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-26 17:34:20","TRT01SDTM":"2019-12-26 17:34:20","AP01SDTM":"2019-12-26 17:34:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5598,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.78887,"AVALU":"U/L","BASE2":28.58483,"BASE":3.65778,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.79596,"PCHG2":-30.77141,"CHG":16.13109,"PCHG":441.00746,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2020-06-14 17:34:20","ADY":171,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-198","SUBJID":"id-198","SITEID":"NGA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":8.96,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-26 17:34:20","TRT01SDTM":"2019-12-26 17:34:20","AP01SDTM":"2019-12-26 17:34:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1632,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.69196,"AVALU":"U/L","BASE2":28.58483,"BASE":3.65778,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-26.89287,"PCHG2":-94.0809,"CHG":-1.96582,"PCHG":-53.74343,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-3","BTOXGR":"-4","ADTM":"2020-08-28 17:34:20","ADY":246,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-198","SUBJID":"id-198","SITEID":"NGA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":8.96,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-26 17:34:20","TRT01SDTM":"2019-12-26 17:34:20","AP01SDTM":"2019-12-26 17:34:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5503,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.31567,"AVALU":"U/L","BASE2":28.58483,"BASE":3.65778,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.26916,"PCHG2":-28.92851,"CHG":16.65788,"PCHG":455.40939,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2020-09-20 17:34:20","ADY":269,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-198","SUBJID":"id-198","SITEID":"NGA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":8.96,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-26 17:34:20","TRT01SDTM":"2019-12-26 17:34:20","AP01SDTM":"2019-12-26 17:34:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":732,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.41444,"AVALU":"U/L","BASE2":28.58483,"BASE":3.65778,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.17039,"PCHG2":-46.07474,"CHG":11.75666,"PCHG":321.41504,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-05-25 17:34:20","ADY":516,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-198","SUBJID":"id-198","SITEID":"NGA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":8.96,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-26 17:34:20","TRT01SDTM":"2019-12-26 17:34:20","AP01SDTM":"2019-12-26 17:34:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6221,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.37277,"AVALU":"U/L","BASE2":28.58483,"BASE":3.65778,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.21206,"PCHG2":-35.72546,"CHG":14.71499,"PCHG":402.29257,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-09-05 17:34:20","ADY":619,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-198","SUBJID":"id-198","SITEID":"NGA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":8.96,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-26 17:34:20","TRT01SDTM":"2019-12-26 17:34:20","AP01SDTM":"2019-12-26 17:34:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":553,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.3095,"AVALU":"mg/L","BASE2":9.3095,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-04-19 17:34:20","ADY":115,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-198","SUBJID":"id-198","SITEID":"NGA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":8.96,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-26 17:34:20","TRT01SDTM":"2019-12-26 17:34:20","AP01SDTM":"2019-12-26 17:34:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":680,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.96987,"AVALU":"mg/L","BASE2":9.3095,"BASE":7.96987,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.33963,"PCHG2":-14.38996,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2020-04-25 17:34:20","ADY":121,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-198","SUBJID":"id-198","SITEID":"NGA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":8.96,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-26 17:34:20","TRT01SDTM":"2019-12-26 17:34:20","AP01SDTM":"2019-12-26 17:34:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2896,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.76768,"AVALU":"mg/L","BASE2":9.3095,"BASE":7.96987,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.54182,"PCHG2":-5.82009,"CHG":0.79781,"PCHG":10.01036,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-06-14 17:34:20","ADY":171,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-198","SUBJID":"id-198","SITEID":"NGA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":8.96,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-26 17:34:20","TRT01SDTM":"2019-12-26 17:34:20","AP01SDTM":"2019-12-26 17:34:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2452,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.18917,"AVALU":"mg/L","BASE2":9.3095,"BASE":7.96987,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.12034,"PCHG2":-22.77605,"CHG":-0.7807,"PCHG":-9.79569,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-2","BTOXGR":"-1","ADTM":"2020-08-28 17:34:20","ADY":246,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-198","SUBJID":"id-198","SITEID":"NGA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":8.96,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-26 17:34:20","TRT01SDTM":"2019-12-26 17:34:20","AP01SDTM":"2019-12-26 17:34:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3423,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.10836,"AVALU":"mg/L","BASE2":9.3095,"BASE":7.96987,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.79885,"PCHG2":8.58106,"CHG":2.13849,"PCHG":26.83216,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"1","BTOXGR":"-1","ADTM":"2020-09-20 17:34:20","ADY":269,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-198","SUBJID":"id-198","SITEID":"NGA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":8.96,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-26 17:34:20","TRT01SDTM":"2019-12-26 17:34:20","AP01SDTM":"2019-12-26 17:34:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2174,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.49643,"AVALU":"mg/L","BASE2":9.3095,"BASE":7.96987,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18693,"PCHG2":2.00797,"CHG":1.52657,"PCHG":19.15421,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-05-25 17:34:20","ADY":516,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-198","SUBJID":"id-198","SITEID":"NGA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":8.96,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-26 17:34:20","TRT01SDTM":"2019-12-26 17:34:20","AP01SDTM":"2019-12-26 17:34:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6002,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.88568,"AVALU":"mg/L","BASE2":9.3095,"BASE":7.96987,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.57618,"PCHG2":6.18915,"CHG":1.91581,"PCHG":24.0382,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-09-05 17:34:20","ADY":619,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-198","SUBJID":"id-198","SITEID":"NGA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":8.96,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-26 17:34:20","TRT01SDTM":"2019-12-26 17:34:20","AP01SDTM":"2019-12-26 17:34:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5102,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95182,"AVALU":"g/L","BASE2":2.95182,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-19 17:34:20","ADY":115,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-198","SUBJID":"id-198","SITEID":"NGA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":8.96,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-26 17:34:20","TRT01SDTM":"2019-12-26 17:34:20","AP01SDTM":"2019-12-26 17:34:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5391,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93827,"AVALU":"g/L","BASE2":2.95182,"BASE":2.93827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.01355,"PCHG2":-0.45898,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-25 17:34:20","ADY":121,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-198","SUBJID":"id-198","SITEID":"NGA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":8.96,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-26 17:34:20","TRT01SDTM":"2019-12-26 17:34:20","AP01SDTM":"2019-12-26 17:34:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7638,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96292,"AVALU":"g/L","BASE2":2.95182,"BASE":2.93827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0111,"PCHG2":0.37597,"CHG":0.02465,"PCHG":0.8388,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-14 17:34:20","ADY":171,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-198","SUBJID":"id-198","SITEID":"NGA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":8.96,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-26 17:34:20","TRT01SDTM":"2019-12-26 17:34:20","AP01SDTM":"2019-12-26 17:34:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":700,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95354,"AVALU":"g/L","BASE2":2.95182,"BASE":2.93827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00172,"PCHG2":0.05821,"CHG":0.01527,"PCHG":0.51958,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-28 17:34:20","ADY":246,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-198","SUBJID":"id-198","SITEID":"NGA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":8.96,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-26 17:34:20","TRT01SDTM":"2019-12-26 17:34:20","AP01SDTM":"2019-12-26 17:34:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6326,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88657,"AVALU":"g/L","BASE2":2.95182,"BASE":2.93827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06525,"PCHG2":-2.21063,"CHG":-0.05171,"PCHG":-1.75972,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-20 17:34:20","ADY":269,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-198","SUBJID":"id-198","SITEID":"NGA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":8.96,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-26 17:34:20","TRT01SDTM":"2019-12-26 17:34:20","AP01SDTM":"2019-12-26 17:34:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6088,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.18697,"AVALU":"g/L","BASE2":2.95182,"BASE":2.93827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.23516,"PCHG2":7.96647,"CHG":0.2487,"PCHG":8.46431,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-05-25 17:34:20","ADY":516,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-198","SUBJID":"id-198","SITEID":"NGA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":8.96,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-26 17:34:20","TRT01SDTM":"2019-12-26 17:34:20","AP01SDTM":"2019-12-26 17:34:20","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5399,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.07421,"AVALU":"g/L","BASE2":2.95182,"BASE":2.93827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12239,"PCHG2":4.1464,"CHG":0.13594,"PCHG":4.62662,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-09-05 17:34:20","ADY":619,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-200","SUBJID":"id-200","SITEID":"NGA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.92477,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-30","TRTSDTM":"2019-09-01 00:38:52","TRTEDTM":"2022-08-31 18:38:52","TRT01SDTM":"2019-09-01 00:38:52","TRT01EDTM":"2021-08-31 12:38:52","TRT02SDTM":"2021-08-31 12:38:52","TRT02EDTM":"2022-08-31 18:38:52","AP01SDTM":"2019-09-01 00:38:52","AP01EDTM":"2021-08-31 12:38:52","AP02SDTM":"2021-08-31 12:38:52","AP02EDTM":"2022-08-31 18:38:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-31","EOSDY":1096,"LSTALVDT":"2022-09-28","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":212,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.07868,"AVALU":"U/L","BASE2":30.07868,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-20 00:38:52","ADY":19,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-200","SUBJID":"id-200","SITEID":"NGA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.92477,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-30","TRTSDTM":"2019-09-01 00:38:52","TRTEDTM":"2022-08-31 18:38:52","TRT01SDTM":"2019-09-01 00:38:52","TRT01EDTM":"2021-08-31 12:38:52","TRT02SDTM":"2021-08-31 12:38:52","TRT02EDTM":"2022-08-31 18:38:52","AP01SDTM":"2019-09-01 00:38:52","AP01EDTM":"2021-08-31 12:38:52","AP02SDTM":"2021-08-31 12:38:52","AP02EDTM":"2022-08-31 18:38:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-31","EOSDY":1096,"LSTALVDT":"2022-09-28","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2678,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.72924,"AVALU":"U/L","BASE2":30.07868,"BASE":17.72924,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-12.34944,"PCHG2":-41.05711,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-05 00:38:52","ADY":217,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-200","SUBJID":"id-200","SITEID":"NGA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.92477,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-30","TRTSDTM":"2019-09-01 00:38:52","TRTEDTM":"2022-08-31 18:38:52","TRT01SDTM":"2019-09-01 00:38:52","TRT01EDTM":"2021-08-31 12:38:52","TRT02SDTM":"2021-08-31 12:38:52","TRT02EDTM":"2022-08-31 18:38:52","AP01SDTM":"2019-09-01 00:38:52","AP01EDTM":"2021-08-31 12:38:52","AP02SDTM":"2021-08-31 12:38:52","AP02EDTM":"2022-08-31 18:38:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-31","EOSDY":1096,"LSTALVDT":"2022-09-28","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2804,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.625,"AVALU":"U/L","BASE2":30.07868,"BASE":17.72924,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-20.45367,"PCHG2":-68.00058,"CHG":-8.10424,"PCHG":-45.71114,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-20 00:38:52","ADY":262,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-200","SUBJID":"id-200","SITEID":"NGA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.92477,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-30","TRTSDTM":"2019-09-01 00:38:52","TRTEDTM":"2022-08-31 18:38:52","TRT01SDTM":"2019-09-01 00:38:52","TRT01EDTM":"2021-08-31 12:38:52","TRT02SDTM":"2021-08-31 12:38:52","TRT02EDTM":"2022-08-31 18:38:52","AP01SDTM":"2019-09-01 00:38:52","AP01EDTM":"2021-08-31 12:38:52","AP02SDTM":"2021-08-31 12:38:52","AP02EDTM":"2022-08-31 18:38:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-31","EOSDY":1096,"LSTALVDT":"2022-09-28","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":437,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.06675,"AVALU":"U/L","BASE2":30.07868,"BASE":17.72924,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.01192,"PCHG2":-3.36425,"CHG":11.33751,"PCHG":63.9481,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-18 00:38:52","ADY":625,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-200","SUBJID":"id-200","SITEID":"NGA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.92477,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-30","TRTSDTM":"2019-09-01 00:38:52","TRTEDTM":"2022-08-31 18:38:52","TRT01SDTM":"2019-09-01 00:38:52","TRT01EDTM":"2021-08-31 12:38:52","TRT02SDTM":"2021-08-31 12:38:52","TRT02EDTM":"2022-08-31 18:38:52","AP01SDTM":"2019-09-01 00:38:52","AP01EDTM":"2021-08-31 12:38:52","AP02SDTM":"2021-08-31 12:38:52","AP02EDTM":"2022-08-31 18:38:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-31","EOSDY":1096,"LSTALVDT":"2022-09-28","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5182,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.90725,"AVALU":"U/L","BASE2":30.07868,"BASE":17.72924,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-18.17142,"PCHG2":-60.41298,"CHG":-5.82199,"PCHG":-32.83834,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-29 00:38:52","ADY":667,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-200","SUBJID":"id-200","SITEID":"NGA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.92477,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-30","TRTSDTM":"2019-09-01 00:38:52","TRTEDTM":"2022-08-31 18:38:52","TRT01SDTM":"2019-09-01 00:38:52","TRT01EDTM":"2021-08-31 12:38:52","TRT02SDTM":"2021-08-31 12:38:52","TRT02EDTM":"2022-08-31 18:38:52","AP01SDTM":"2019-09-01 00:38:52","AP01EDTM":"2021-08-31 12:38:52","AP02SDTM":"2021-08-31 12:38:52","AP02EDTM":"2022-08-31 18:38:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-31","EOSDY":1096,"LSTALVDT":"2022-09-28","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8227,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.76675,"AVALU":"U/L","BASE2":30.07868,"BASE":17.72924,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.31192,"PCHG2":-7.68626,"CHG":10.03751,"PCHG":56.61558,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-16 00:38:52","ADY":776,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-200","SUBJID":"id-200","SITEID":"NGA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.92477,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-30","TRTSDTM":"2019-09-01 00:38:52","TRTEDTM":"2022-08-31 18:38:52","TRT01SDTM":"2019-09-01 00:38:52","TRT01EDTM":"2021-08-31 12:38:52","TRT02SDTM":"2021-08-31 12:38:52","TRT02EDTM":"2022-08-31 18:38:52","AP01SDTM":"2019-09-01 00:38:52","AP01EDTM":"2021-08-31 12:38:52","AP02SDTM":"2021-08-31 12:38:52","AP02EDTM":"2022-08-31 18:38:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-31","EOSDY":1096,"LSTALVDT":"2022-09-28","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4734,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.44322,"AVALU":"U/L","BASE2":30.07868,"BASE":17.72924,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.63546,"PCHG2":-38.6834,"CHG":0.71398,"PCHG":4.02714,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-22 00:38:52","ADY":813,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-200","SUBJID":"id-200","SITEID":"NGA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.92477,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-30","TRTSDTM":"2019-09-01 00:38:52","TRTEDTM":"2022-08-31 18:38:52","TRT01SDTM":"2019-09-01 00:38:52","TRT01EDTM":"2021-08-31 12:38:52","TRT02SDTM":"2021-08-31 12:38:52","TRT02EDTM":"2022-08-31 18:38:52","AP01SDTM":"2019-09-01 00:38:52","AP01EDTM":"2021-08-31 12:38:52","AP02SDTM":"2021-08-31 12:38:52","AP02EDTM":"2022-08-31 18:38:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-31","EOSDY":1096,"LSTALVDT":"2022-09-28","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4179,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.63031,"AVALU":"mg/L","BASE2":9.63031,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-20 00:38:52","ADY":19,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-200","SUBJID":"id-200","SITEID":"NGA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.92477,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-30","TRTSDTM":"2019-09-01 00:38:52","TRTEDTM":"2022-08-31 18:38:52","TRT01SDTM":"2019-09-01 00:38:52","TRT01EDTM":"2021-08-31 12:38:52","TRT02SDTM":"2021-08-31 12:38:52","TRT02EDTM":"2022-08-31 18:38:52","AP01SDTM":"2019-09-01 00:38:52","AP01EDTM":"2021-08-31 12:38:52","AP02SDTM":"2021-08-31 12:38:52","AP02EDTM":"2022-08-31 18:38:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-31","EOSDY":1096,"LSTALVDT":"2022-09-28","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6861,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.18654,"AVALU":"mg/L","BASE2":9.63031,"BASE":9.18654,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.44377,"PCHG2":-4.60804,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-05 00:38:52","ADY":217,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-200","SUBJID":"id-200","SITEID":"NGA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.92477,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-30","TRTSDTM":"2019-09-01 00:38:52","TRTEDTM":"2022-08-31 18:38:52","TRT01SDTM":"2019-09-01 00:38:52","TRT01EDTM":"2021-08-31 12:38:52","TRT02SDTM":"2021-08-31 12:38:52","TRT02EDTM":"2022-08-31 18:38:52","AP01SDTM":"2019-09-01 00:38:52","AP01EDTM":"2021-08-31 12:38:52","AP02SDTM":"2021-08-31 12:38:52","AP02EDTM":"2022-08-31 18:38:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-31","EOSDY":1096,"LSTALVDT":"2022-09-28","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7042,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.41363,"AVALU":"mg/L","BASE2":9.63031,"BASE":9.18654,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21668,"PCHG2":-2.25002,"CHG":0.22708,"PCHG":2.47192,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-20 00:38:52","ADY":262,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-200","SUBJID":"id-200","SITEID":"NGA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.92477,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-30","TRTSDTM":"2019-09-01 00:38:52","TRTEDTM":"2022-08-31 18:38:52","TRT01SDTM":"2019-09-01 00:38:52","TRT01EDTM":"2021-08-31 12:38:52","TRT02SDTM":"2021-08-31 12:38:52","TRT02EDTM":"2022-08-31 18:38:52","AP01SDTM":"2019-09-01 00:38:52","AP01EDTM":"2021-08-31 12:38:52","AP02SDTM":"2021-08-31 12:38:52","AP02EDTM":"2022-08-31 18:38:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-31","EOSDY":1096,"LSTALVDT":"2022-09-28","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5548,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.15251,"AVALU":"mg/L","BASE2":9.63031,"BASE":9.18654,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.5222,"PCHG2":5.42246,"CHG":0.96597,"PCHG":10.51504,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-05-18 00:38:52","ADY":625,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-200","SUBJID":"id-200","SITEID":"NGA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.92477,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-30","TRTSDTM":"2019-09-01 00:38:52","TRTEDTM":"2022-08-31 18:38:52","TRT01SDTM":"2019-09-01 00:38:52","TRT01EDTM":"2021-08-31 12:38:52","TRT02SDTM":"2021-08-31 12:38:52","TRT02EDTM":"2022-08-31 18:38:52","AP01SDTM":"2019-09-01 00:38:52","AP01EDTM":"2021-08-31 12:38:52","AP02SDTM":"2021-08-31 12:38:52","AP02EDTM":"2022-08-31 18:38:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-31","EOSDY":1096,"LSTALVDT":"2022-09-28","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4230,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.08498,"AVALU":"mg/L","BASE2":9.63031,"BASE":9.18654,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.54533,"PCHG2":-5.66266,"CHG":-0.10156,"PCHG":-1.10557,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-29 00:38:52","ADY":667,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-200","SUBJID":"id-200","SITEID":"NGA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.92477,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-30","TRTSDTM":"2019-09-01 00:38:52","TRTEDTM":"2022-08-31 18:38:52","TRT01SDTM":"2019-09-01 00:38:52","TRT01EDTM":"2021-08-31 12:38:52","TRT02SDTM":"2021-08-31 12:38:52","TRT02EDTM":"2022-08-31 18:38:52","AP01SDTM":"2019-09-01 00:38:52","AP01EDTM":"2021-08-31 12:38:52","AP02SDTM":"2021-08-31 12:38:52","AP02EDTM":"2022-08-31 18:38:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-31","EOSDY":1096,"LSTALVDT":"2022-09-28","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":514,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.86542,"AVALU":"mg/L","BASE2":9.63031,"BASE":9.18654,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.76489,"PCHG2":-7.9425,"CHG":-0.32112,"PCHG":-3.49554,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-16 00:38:52","ADY":776,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-200","SUBJID":"id-200","SITEID":"NGA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.92477,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-30","TRTSDTM":"2019-09-01 00:38:52","TRTEDTM":"2022-08-31 18:38:52","TRT01SDTM":"2019-09-01 00:38:52","TRT01EDTM":"2021-08-31 12:38:52","TRT02SDTM":"2021-08-31 12:38:52","TRT02EDTM":"2022-08-31 18:38:52","AP01SDTM":"2019-09-01 00:38:52","AP01EDTM":"2021-08-31 12:38:52","AP02SDTM":"2021-08-31 12:38:52","AP02EDTM":"2022-08-31 18:38:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-31","EOSDY":1096,"LSTALVDT":"2022-09-28","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5255,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.76812,"AVALU":"mg/L","BASE2":9.63031,"BASE":9.18654,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.86219,"PCHG2":-19.33675,"CHG":-1.41842,"PCHG":-15.44021,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-11-22 00:38:52","ADY":813,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-200","SUBJID":"id-200","SITEID":"NGA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.92477,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-30","TRTSDTM":"2019-09-01 00:38:52","TRTEDTM":"2022-08-31 18:38:52","TRT01SDTM":"2019-09-01 00:38:52","TRT01EDTM":"2021-08-31 12:38:52","TRT02SDTM":"2021-08-31 12:38:52","TRT02EDTM":"2022-08-31 18:38:52","AP01SDTM":"2019-09-01 00:38:52","AP01EDTM":"2021-08-31 12:38:52","AP02SDTM":"2021-08-31 12:38:52","AP02EDTM":"2022-08-31 18:38:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-31","EOSDY":1096,"LSTALVDT":"2022-09-28","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8119,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9551,"AVALU":"g/L","BASE2":2.9551,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-20 00:38:52","ADY":19,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-200","SUBJID":"id-200","SITEID":"NGA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.92477,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-30","TRTSDTM":"2019-09-01 00:38:52","TRTEDTM":"2022-08-31 18:38:52","TRT01SDTM":"2019-09-01 00:38:52","TRT01EDTM":"2021-08-31 12:38:52","TRT02SDTM":"2021-08-31 12:38:52","TRT02EDTM":"2022-08-31 18:38:52","AP01SDTM":"2019-09-01 00:38:52","AP01EDTM":"2021-08-31 12:38:52","AP02SDTM":"2021-08-31 12:38:52","AP02EDTM":"2022-08-31 18:38:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-31","EOSDY":1096,"LSTALVDT":"2022-09-28","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3708,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8748,"AVALU":"g/L","BASE2":2.9551,"BASE":2.8748,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.0803,"PCHG2":-2.71731,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-05 00:38:52","ADY":217,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-200","SUBJID":"id-200","SITEID":"NGA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.92477,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-30","TRTSDTM":"2019-09-01 00:38:52","TRTEDTM":"2022-08-31 18:38:52","TRT01SDTM":"2019-09-01 00:38:52","TRT01EDTM":"2021-08-31 12:38:52","TRT02SDTM":"2021-08-31 12:38:52","TRT02EDTM":"2022-08-31 18:38:52","AP01SDTM":"2019-09-01 00:38:52","AP01EDTM":"2021-08-31 12:38:52","AP02SDTM":"2021-08-31 12:38:52","AP02EDTM":"2022-08-31 18:38:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-31","EOSDY":1096,"LSTALVDT":"2022-09-28","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4114,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93811,"AVALU":"g/L","BASE2":2.9551,"BASE":2.8748,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01699,"PCHG2":-0.57506,"CHG":0.06331,"PCHG":2.20209,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-20 00:38:52","ADY":262,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-200","SUBJID":"id-200","SITEID":"NGA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.92477,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-30","TRTSDTM":"2019-09-01 00:38:52","TRTEDTM":"2022-08-31 18:38:52","TRT01SDTM":"2019-09-01 00:38:52","TRT01EDTM":"2021-08-31 12:38:52","TRT02SDTM":"2021-08-31 12:38:52","TRT02EDTM":"2022-08-31 18:38:52","AP01SDTM":"2019-09-01 00:38:52","AP01EDTM":"2021-08-31 12:38:52","AP02SDTM":"2021-08-31 12:38:52","AP02EDTM":"2022-08-31 18:38:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-31","EOSDY":1096,"LSTALVDT":"2022-09-28","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1253,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86283,"AVALU":"g/L","BASE2":2.9551,"BASE":2.8748,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09227,"PCHG2":-3.12234,"CHG":-0.01197,"PCHG":-0.41634,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-18 00:38:52","ADY":625,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-200","SUBJID":"id-200","SITEID":"NGA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.92477,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-30","TRTSDTM":"2019-09-01 00:38:52","TRTEDTM":"2022-08-31 18:38:52","TRT01SDTM":"2019-09-01 00:38:52","TRT01EDTM":"2021-08-31 12:38:52","TRT02SDTM":"2021-08-31 12:38:52","TRT02EDTM":"2022-08-31 18:38:52","AP01SDTM":"2019-09-01 00:38:52","AP01EDTM":"2021-08-31 12:38:52","AP02SDTM":"2021-08-31 12:38:52","AP02EDTM":"2022-08-31 18:38:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-31","EOSDY":1096,"LSTALVDT":"2022-09-28","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3394,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91751,"AVALU":"g/L","BASE2":2.9551,"BASE":2.8748,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03759,"PCHG2":-1.27208,"CHG":0.04271,"PCHG":1.4856,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-29 00:38:52","ADY":667,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-200","SUBJID":"id-200","SITEID":"NGA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.92477,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-30","TRTSDTM":"2019-09-01 00:38:52","TRTEDTM":"2022-08-31 18:38:52","TRT01SDTM":"2019-09-01 00:38:52","TRT01EDTM":"2021-08-31 12:38:52","TRT02SDTM":"2021-08-31 12:38:52","TRT02EDTM":"2022-08-31 18:38:52","AP01SDTM":"2019-09-01 00:38:52","AP01EDTM":"2021-08-31 12:38:52","AP02SDTM":"2021-08-31 12:38:52","AP02EDTM":"2022-08-31 18:38:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-31","EOSDY":1096,"LSTALVDT":"2022-09-28","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5770,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9007,"AVALU":"g/L","BASE2":2.9551,"BASE":2.8748,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05441,"PCHG2":-1.84107,"CHG":0.02589,"PCHG":0.90071,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-16 00:38:52","ADY":776,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-200","SUBJID":"id-200","SITEID":"NGA-1","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.92477,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-30","TRTSDTM":"2019-09-01 00:38:52","TRTEDTM":"2022-08-31 18:38:52","TRT01SDTM":"2019-09-01 00:38:52","TRT01EDTM":"2021-08-31 12:38:52","TRT02SDTM":"2021-08-31 12:38:52","TRT02EDTM":"2022-08-31 18:38:52","AP01SDTM":"2019-09-01 00:38:52","AP01EDTM":"2021-08-31 12:38:52","AP02SDTM":"2021-08-31 12:38:52","AP02EDTM":"2022-08-31 18:38:52","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-31","EOSDY":1096,"LSTALVDT":"2022-09-28","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1256,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8122,"AVALU":"g/L","BASE2":2.9551,"BASE":2.8748,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14291,"PCHG2":-4.8359,"CHG":-0.06261,"PCHG":-2.17777,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-22 00:38:52","ADY":813,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-325","SUBJID":"id-325","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":7.97282,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-08 13:23:00","TRTEDTM":"2022-02-15 18:16:55","TRT01SDTM":"2019-09-08 13:23:00","TRT01EDTM":"2021-02-15 12:16:55","TRT02SDTM":"2021-02-15 12:16:55","TRT02EDTM":"2022-02-15 18:16:55","AP01SDTM":"2019-09-08 13:23:00","AP01EDTM":"2021-02-15 12:16:55","AP02SDTM":"2021-02-15 12:16:55","AP02EDTM":"2022-02-15 18:16:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":892,"DCSREAS":"DEATH","DTHDT":"2022-04-01","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":45,"LDDTHGR1":">30","LSTALVDT":"2022-04-01","DTHADY":935,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7045,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.00214,"AVALU":"U/L","BASE2":25.00214,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-16 13:23:00","ADY":69,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-325","SUBJID":"id-325","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":7.97282,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-08 13:23:00","TRTEDTM":"2022-02-15 18:16:55","TRT01SDTM":"2019-09-08 13:23:00","TRT01EDTM":"2021-02-15 12:16:55","TRT02SDTM":"2021-02-15 12:16:55","TRT02EDTM":"2022-02-15 18:16:55","AP01SDTM":"2019-09-08 13:23:00","AP01EDTM":"2021-02-15 12:16:55","AP02SDTM":"2021-02-15 12:16:55","AP02EDTM":"2022-02-15 18:16:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":892,"DCSREAS":"DEATH","DTHDT":"2022-04-01","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":45,"LDDTHGR1":">30","LSTALVDT":"2022-04-01","DTHADY":935,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1790,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.8564,"AVALU":"U/L","BASE2":25.00214,"BASE":29.8564,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":4.85426,"PCHG2":19.4154,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-27 13:23:00","ADY":172,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-325","SUBJID":"id-325","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":7.97282,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-08 13:23:00","TRTEDTM":"2022-02-15 18:16:55","TRT01SDTM":"2019-09-08 13:23:00","TRT01EDTM":"2021-02-15 12:16:55","TRT02SDTM":"2021-02-15 12:16:55","TRT02EDTM":"2022-02-15 18:16:55","AP01SDTM":"2019-09-08 13:23:00","AP01EDTM":"2021-02-15 12:16:55","AP02SDTM":"2021-02-15 12:16:55","AP02EDTM":"2022-02-15 18:16:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":892,"DCSREAS":"DEATH","DTHDT":"2022-04-01","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":45,"LDDTHGR1":">30","LSTALVDT":"2022-04-01","DTHADY":935,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7130,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.03786,"AVALU":"U/L","BASE2":25.00214,"BASE":29.8564,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.96427,"PCHG2":-67.85129,"CHG":-21.81854,"PCHG":-73.07825,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-12 13:23:00","ADY":308,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-325","SUBJID":"id-325","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":7.97282,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-08 13:23:00","TRTEDTM":"2022-02-15 18:16:55","TRT01SDTM":"2019-09-08 13:23:00","TRT01EDTM":"2021-02-15 12:16:55","TRT02SDTM":"2021-02-15 12:16:55","TRT02EDTM":"2022-02-15 18:16:55","AP01SDTM":"2019-09-08 13:23:00","AP01EDTM":"2021-02-15 12:16:55","AP02SDTM":"2021-02-15 12:16:55","AP02EDTM":"2022-02-15 18:16:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":892,"DCSREAS":"DEATH","DTHDT":"2022-04-01","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":45,"LDDTHGR1":">30","LSTALVDT":"2022-04-01","DTHADY":935,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2941,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.0211,"AVALU":"U/L","BASE2":25.00214,"BASE":29.8564,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.98104,"PCHG2":-43.92039,"CHG":-15.8353,"PCHG":-53.03821,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-15 13:23:00","ADY":434,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-325","SUBJID":"id-325","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":7.97282,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-08 13:23:00","TRTEDTM":"2022-02-15 18:16:55","TRT01SDTM":"2019-09-08 13:23:00","TRT01EDTM":"2021-02-15 12:16:55","TRT02SDTM":"2021-02-15 12:16:55","TRT02EDTM":"2022-02-15 18:16:55","AP01SDTM":"2019-09-08 13:23:00","AP01EDTM":"2021-02-15 12:16:55","AP02SDTM":"2021-02-15 12:16:55","AP02EDTM":"2022-02-15 18:16:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":892,"DCSREAS":"DEATH","DTHDT":"2022-04-01","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":45,"LDDTHGR1":">30","LSTALVDT":"2022-04-01","DTHADY":935,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3201,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.54852,"AVALU":"U/L","BASE2":25.00214,"BASE":29.8564,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.45361,"PCHG2":-41.81089,"CHG":-15.30788,"PCHG":-51.27168,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-19 13:23:00","ADY":558,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-325","SUBJID":"id-325","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":7.97282,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-08 13:23:00","TRTEDTM":"2022-02-15 18:16:55","TRT01SDTM":"2019-09-08 13:23:00","TRT01EDTM":"2021-02-15 12:16:55","TRT02SDTM":"2021-02-15 12:16:55","TRT02EDTM":"2022-02-15 18:16:55","AP01SDTM":"2019-09-08 13:23:00","AP01EDTM":"2021-02-15 12:16:55","AP02SDTM":"2021-02-15 12:16:55","AP02EDTM":"2022-02-15 18:16:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":892,"DCSREAS":"DEATH","DTHDT":"2022-04-01","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":45,"LDDTHGR1":">30","LSTALVDT":"2022-04-01","DTHADY":935,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4991,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.92498,"AVALU":"U/L","BASE2":25.00214,"BASE":29.8564,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-15.07716,"PCHG2":-60.30349,"CHG":-19.93142,"PCHG":-66.75763,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-17 13:23:00","ADY":648,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-325","SUBJID":"id-325","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":7.97282,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-08 13:23:00","TRTEDTM":"2022-02-15 18:16:55","TRT01SDTM":"2019-09-08 13:23:00","TRT01EDTM":"2021-02-15 12:16:55","TRT02SDTM":"2021-02-15 12:16:55","TRT02EDTM":"2022-02-15 18:16:55","AP01SDTM":"2019-09-08 13:23:00","AP01EDTM":"2021-02-15 12:16:55","AP02SDTM":"2021-02-15 12:16:55","AP02EDTM":"2022-02-15 18:16:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":892,"DCSREAS":"DEATH","DTHDT":"2022-04-01","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":45,"LDDTHGR1":">30","LSTALVDT":"2022-04-01","DTHADY":935,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2733,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.97466,"AVALU":"U/L","BASE2":25.00214,"BASE":29.8564,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.97252,"PCHG2":15.88873,"CHG":-0.88174,"PCHG":-2.95328,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-31 13:23:00","ADY":845,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-325","SUBJID":"id-325","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":7.97282,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-08 13:23:00","TRTEDTM":"2022-02-15 18:16:55","TRT01SDTM":"2019-09-08 13:23:00","TRT01EDTM":"2021-02-15 12:16:55","TRT02SDTM":"2021-02-15 12:16:55","TRT02EDTM":"2022-02-15 18:16:55","AP01SDTM":"2019-09-08 13:23:00","AP01EDTM":"2021-02-15 12:16:55","AP02SDTM":"2021-02-15 12:16:55","AP02EDTM":"2022-02-15 18:16:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":892,"DCSREAS":"DEATH","DTHDT":"2022-04-01","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":45,"LDDTHGR1":">30","LSTALVDT":"2022-04-01","DTHADY":935,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2338,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.63499,"AVALU":"mg/L","BASE2":10.63499,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"","ATOXGR":"4","BTOXGR":"-1","ADTM":"2019-11-16 13:23:00","ADY":69,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-325","SUBJID":"id-325","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":7.97282,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-08 13:23:00","TRTEDTM":"2022-02-15 18:16:55","TRT01SDTM":"2019-09-08 13:23:00","TRT01EDTM":"2021-02-15 12:16:55","TRT02SDTM":"2021-02-15 12:16:55","TRT02EDTM":"2022-02-15 18:16:55","AP01SDTM":"2019-09-08 13:23:00","AP01EDTM":"2021-02-15 12:16:55","AP02SDTM":"2021-02-15 12:16:55","AP02EDTM":"2022-02-15 18:16:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":892,"DCSREAS":"DEATH","DTHDT":"2022-04-01","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":45,"LDDTHGR1":">30","LSTALVDT":"2022-04-01","DTHADY":935,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2697,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.87784,"AVALU":"mg/L","BASE2":10.63499,"BASE":7.87784,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.75715,"PCHG2":-25.92525,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2020-02-27 13:23:00","ADY":172,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-325","SUBJID":"id-325","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":7.97282,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-08 13:23:00","TRTEDTM":"2022-02-15 18:16:55","TRT01SDTM":"2019-09-08 13:23:00","TRT01EDTM":"2021-02-15 12:16:55","TRT02SDTM":"2021-02-15 12:16:55","TRT02EDTM":"2022-02-15 18:16:55","AP01SDTM":"2019-09-08 13:23:00","AP01EDTM":"2021-02-15 12:16:55","AP02SDTM":"2021-02-15 12:16:55","AP02EDTM":"2022-02-15 18:16:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":892,"DCSREAS":"DEATH","DTHDT":"2022-04-01","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":45,"LDDTHGR1":">30","LSTALVDT":"2022-04-01","DTHADY":935,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6647,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.60649,"AVALU":"mg/L","BASE2":10.63499,"BASE":7.87784,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.0285,"PCHG2":-19.07384,"CHG":0.72865,"PCHG":9.24932,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-07-12 13:23:00","ADY":308,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-325","SUBJID":"id-325","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":7.97282,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-08 13:23:00","TRTEDTM":"2022-02-15 18:16:55","TRT01SDTM":"2019-09-08 13:23:00","TRT01EDTM":"2021-02-15 12:16:55","TRT02SDTM":"2021-02-15 12:16:55","TRT02EDTM":"2022-02-15 18:16:55","AP01SDTM":"2019-09-08 13:23:00","AP01EDTM":"2021-02-15 12:16:55","AP02SDTM":"2021-02-15 12:16:55","AP02EDTM":"2022-02-15 18:16:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":892,"DCSREAS":"DEATH","DTHDT":"2022-04-01","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":45,"LDDTHGR1":">30","LSTALVDT":"2022-04-01","DTHADY":935,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4138,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.34384,"AVALU":"mg/L","BASE2":10.63499,"BASE":7.87784,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.29115,"PCHG2":-12.14058,"CHG":1.466,"PCHG":18.60913,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-11-15 13:23:00","ADY":434,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-325","SUBJID":"id-325","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":7.97282,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-08 13:23:00","TRTEDTM":"2022-02-15 18:16:55","TRT01SDTM":"2019-09-08 13:23:00","TRT01EDTM":"2021-02-15 12:16:55","TRT02SDTM":"2021-02-15 12:16:55","TRT02EDTM":"2022-02-15 18:16:55","AP01SDTM":"2019-09-08 13:23:00","AP01EDTM":"2021-02-15 12:16:55","AP02SDTM":"2021-02-15 12:16:55","AP02EDTM":"2022-02-15 18:16:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":892,"DCSREAS":"DEATH","DTHDT":"2022-04-01","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":45,"LDDTHGR1":">30","LSTALVDT":"2022-04-01","DTHADY":935,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":214,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.75757,"AVALU":"mg/L","BASE2":10.63499,"BASE":7.87784,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.87742,"PCHG2":-8.25028,"CHG":1.87973,"PCHG":23.86099,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-03-19 13:23:00","ADY":558,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-325","SUBJID":"id-325","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":7.97282,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-08 13:23:00","TRTEDTM":"2022-02-15 18:16:55","TRT01SDTM":"2019-09-08 13:23:00","TRT01EDTM":"2021-02-15 12:16:55","TRT02SDTM":"2021-02-15 12:16:55","TRT02EDTM":"2022-02-15 18:16:55","AP01SDTM":"2019-09-08 13:23:00","AP01EDTM":"2021-02-15 12:16:55","AP02SDTM":"2021-02-15 12:16:55","AP02EDTM":"2022-02-15 18:16:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":892,"DCSREAS":"DEATH","DTHDT":"2022-04-01","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":45,"LDDTHGR1":">30","LSTALVDT":"2022-04-01","DTHADY":935,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":393,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.99459,"AVALU":"mg/L","BASE2":10.63499,"BASE":7.87784,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.6404,"PCHG2":-6.02162,"CHG":2.11675,"PCHG":26.86965,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-06-17 13:23:00","ADY":648,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-325","SUBJID":"id-325","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":7.97282,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-08 13:23:00","TRTEDTM":"2022-02-15 18:16:55","TRT01SDTM":"2019-09-08 13:23:00","TRT01EDTM":"2021-02-15 12:16:55","TRT02SDTM":"2021-02-15 12:16:55","TRT02EDTM":"2022-02-15 18:16:55","AP01SDTM":"2019-09-08 13:23:00","AP01EDTM":"2021-02-15 12:16:55","AP02SDTM":"2021-02-15 12:16:55","AP02EDTM":"2022-02-15 18:16:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":892,"DCSREAS":"DEATH","DTHDT":"2022-04-01","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":45,"LDDTHGR1":">30","LSTALVDT":"2022-04-01","DTHADY":935,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4998,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.40655,"AVALU":"mg/L","BASE2":10.63499,"BASE":7.87784,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.77156,"PCHG2":7.25496,"CHG":3.52871,"PCHG":44.79287,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"2","BTOXGR":"-1","ADTM":"2021-12-31 13:23:00","ADY":845,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-325","SUBJID":"id-325","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":7.97282,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-08 13:23:00","TRTEDTM":"2022-02-15 18:16:55","TRT01SDTM":"2019-09-08 13:23:00","TRT01EDTM":"2021-02-15 12:16:55","TRT02SDTM":"2021-02-15 12:16:55","TRT02EDTM":"2022-02-15 18:16:55","AP01SDTM":"2019-09-08 13:23:00","AP01EDTM":"2021-02-15 12:16:55","AP02SDTM":"2021-02-15 12:16:55","AP02EDTM":"2022-02-15 18:16:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":892,"DCSREAS":"DEATH","DTHDT":"2022-04-01","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":45,"LDDTHGR1":">30","LSTALVDT":"2022-04-01","DTHADY":935,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5034,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92907,"AVALU":"g/L","BASE2":2.92907,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-16 13:23:00","ADY":69,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-325","SUBJID":"id-325","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":7.97282,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-08 13:23:00","TRTEDTM":"2022-02-15 18:16:55","TRT01SDTM":"2019-09-08 13:23:00","TRT01EDTM":"2021-02-15 12:16:55","TRT02SDTM":"2021-02-15 12:16:55","TRT02EDTM":"2022-02-15 18:16:55","AP01SDTM":"2019-09-08 13:23:00","AP01EDTM":"2021-02-15 12:16:55","AP02SDTM":"2021-02-15 12:16:55","AP02EDTM":"2022-02-15 18:16:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":892,"DCSREAS":"DEATH","DTHDT":"2022-04-01","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":45,"LDDTHGR1":">30","LSTALVDT":"2022-04-01","DTHADY":935,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3462,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88682,"AVALU":"g/L","BASE2":2.92907,"BASE":2.88682,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.04224,"PCHG2":-1.44226,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-27 13:23:00","ADY":172,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-325","SUBJID":"id-325","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":7.97282,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-08 13:23:00","TRTEDTM":"2022-02-15 18:16:55","TRT01SDTM":"2019-09-08 13:23:00","TRT01EDTM":"2021-02-15 12:16:55","TRT02SDTM":"2021-02-15 12:16:55","TRT02EDTM":"2022-02-15 18:16:55","AP01SDTM":"2019-09-08 13:23:00","AP01EDTM":"2021-02-15 12:16:55","AP02SDTM":"2021-02-15 12:16:55","AP02EDTM":"2022-02-15 18:16:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":892,"DCSREAS":"DEATH","DTHDT":"2022-04-01","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":45,"LDDTHGR1":">30","LSTALVDT":"2022-04-01","DTHADY":935,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7733,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88155,"AVALU":"g/L","BASE2":2.92907,"BASE":2.88682,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04752,"PCHG2":-1.62226,"CHG":-0.00527,"PCHG":-0.18263,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-12 13:23:00","ADY":308,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-325","SUBJID":"id-325","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":7.97282,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-08 13:23:00","TRTEDTM":"2022-02-15 18:16:55","TRT01SDTM":"2019-09-08 13:23:00","TRT01EDTM":"2021-02-15 12:16:55","TRT02SDTM":"2021-02-15 12:16:55","TRT02EDTM":"2022-02-15 18:16:55","AP01SDTM":"2019-09-08 13:23:00","AP01EDTM":"2021-02-15 12:16:55","AP02SDTM":"2021-02-15 12:16:55","AP02EDTM":"2022-02-15 18:16:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":892,"DCSREAS":"DEATH","DTHDT":"2022-04-01","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":45,"LDDTHGR1":">30","LSTALVDT":"2022-04-01","DTHADY":935,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2799,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83216,"AVALU":"g/L","BASE2":2.92907,"BASE":2.88682,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0969,"PCHG2":-3.30825,"CHG":-0.05466,"PCHG":-1.89329,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-15 13:23:00","ADY":434,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-325","SUBJID":"id-325","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":7.97282,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-08 13:23:00","TRTEDTM":"2022-02-15 18:16:55","TRT01SDTM":"2019-09-08 13:23:00","TRT01EDTM":"2021-02-15 12:16:55","TRT02SDTM":"2021-02-15 12:16:55","TRT02EDTM":"2022-02-15 18:16:55","AP01SDTM":"2019-09-08 13:23:00","AP01EDTM":"2021-02-15 12:16:55","AP02SDTM":"2021-02-15 12:16:55","AP02EDTM":"2022-02-15 18:16:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":892,"DCSREAS":"DEATH","DTHDT":"2022-04-01","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":45,"LDDTHGR1":">30","LSTALVDT":"2022-04-01","DTHADY":935,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5652,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78581,"AVALU":"g/L","BASE2":2.92907,"BASE":2.88682,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14325,"PCHG2":-4.89071,"CHG":-0.10101,"PCHG":-3.49891,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-19 13:23:00","ADY":558,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-325","SUBJID":"id-325","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":7.97282,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-08 13:23:00","TRTEDTM":"2022-02-15 18:16:55","TRT01SDTM":"2019-09-08 13:23:00","TRT01EDTM":"2021-02-15 12:16:55","TRT02SDTM":"2021-02-15 12:16:55","TRT02EDTM":"2022-02-15 18:16:55","AP01SDTM":"2019-09-08 13:23:00","AP01EDTM":"2021-02-15 12:16:55","AP02SDTM":"2021-02-15 12:16:55","AP02EDTM":"2022-02-15 18:16:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":892,"DCSREAS":"DEATH","DTHDT":"2022-04-01","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":45,"LDDTHGR1":">30","LSTALVDT":"2022-04-01","DTHADY":935,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2121,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87127,"AVALU":"g/L","BASE2":2.92907,"BASE":2.88682,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05779,"PCHG2":-1.97313,"CHG":-0.01555,"PCHG":-0.53863,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-17 13:23:00","ADY":648,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-325","SUBJID":"id-325","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":7.97282,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-07","TRTSDTM":"2019-09-08 13:23:00","TRTEDTM":"2022-02-15 18:16:55","TRT01SDTM":"2019-09-08 13:23:00","TRT01EDTM":"2021-02-15 12:16:55","TRT02SDTM":"2021-02-15 12:16:55","TRT02EDTM":"2022-02-15 18:16:55","AP01SDTM":"2019-09-08 13:23:00","AP01EDTM":"2021-02-15 12:16:55","AP02SDTM":"2021-02-15 12:16:55","AP02EDTM":"2022-02-15 18:16:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":892,"DCSREAS":"DEATH","DTHDT":"2022-04-01","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":45,"LDDTHGR1":">30","LSTALVDT":"2022-04-01","DTHADY":935,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2936,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76216,"AVALU":"g/L","BASE2":2.92907,"BASE":2.88682,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16691,"PCHG2":-5.69832,"CHG":-0.12466,"PCHG":-4.31834,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-31 13:23:00","ADY":845,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-327","SUBJID":"id-327","SITEID":"NGA-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.09908,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-01 08:23:21","TRTEDTM":"2022-02-18 16:58:58","TRT01SDTM":"2020-01-01 08:23:21","TRT01EDTM":"2021-02-18 10:58:58","TRT02SDTM":"2021-02-18 10:58:58","TRT02EDTM":"2022-02-18 16:58:58","AP01SDTM":"2020-01-01 08:23:21","AP01EDTM":"2021-02-18 10:58:58","AP02SDTM":"2021-02-18 10:58:58","AP02EDTM":"2022-02-18 16:58:58","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-16","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":98,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.75505,"AVALU":"U/L","BASE2":3.75505,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2020-03-18 08:23:21","ADY":77,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-327","SUBJID":"id-327","SITEID":"NGA-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.09908,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-01 08:23:21","TRTEDTM":"2022-02-18 16:58:58","TRT01SDTM":"2020-01-01 08:23:21","TRT01EDTM":"2021-02-18 10:58:58","TRT02SDTM":"2021-02-18 10:58:58","TRT02EDTM":"2022-02-18 16:58:58","AP01SDTM":"2020-01-01 08:23:21","AP01EDTM":"2021-02-18 10:58:58","AP02SDTM":"2021-02-18 10:58:58","AP02EDTM":"2022-02-18 16:58:58","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-16","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7908,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.94495,"AVALU":"U/L","BASE2":3.75505,"BASE":3.94495,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.18989,"PCHG2":5.05697,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2020-05-22 08:23:21","ADY":142,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-327","SUBJID":"id-327","SITEID":"NGA-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.09908,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-01 08:23:21","TRTEDTM":"2022-02-18 16:58:58","TRT01SDTM":"2020-01-01 08:23:21","TRT01EDTM":"2021-02-18 10:58:58","TRT02SDTM":"2021-02-18 10:58:58","TRT02EDTM":"2022-02-18 16:58:58","AP01SDTM":"2020-01-01 08:23:21","AP01EDTM":"2021-02-18 10:58:58","AP02SDTM":"2021-02-18 10:58:58","AP02EDTM":"2022-02-18 16:58:58","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-16","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7627,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":37.86638,"AVALU":"U/L","BASE2":3.75505,"BASE":3.94495,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":34.11132,"PCHG2":908.41114,"CHG":33.92143,"PCHG":859.87073,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2020-10-30 08:23:21","ADY":303,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-327","SUBJID":"id-327","SITEID":"NGA-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.09908,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-01 08:23:21","TRTEDTM":"2022-02-18 16:58:58","TRT01SDTM":"2020-01-01 08:23:21","TRT01EDTM":"2021-02-18 10:58:58","TRT02SDTM":"2021-02-18 10:58:58","TRT02EDTM":"2022-02-18 16:58:58","AP01SDTM":"2020-01-01 08:23:21","AP01EDTM":"2021-02-18 10:58:58","AP02SDTM":"2021-02-18 10:58:58","AP02EDTM":"2022-02-18 16:58:58","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-16","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5260,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.24034,"AVALU":"U/L","BASE2":3.75505,"BASE":3.94495,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.48528,"PCHG2":172.70819,"CHG":6.29539,"PCHG":159.58124,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-02-24 08:23:21","ADY":420,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-327","SUBJID":"id-327","SITEID":"NGA-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.09908,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-01 08:23:21","TRTEDTM":"2022-02-18 16:58:58","TRT01SDTM":"2020-01-01 08:23:21","TRT01EDTM":"2021-02-18 10:58:58","TRT02SDTM":"2021-02-18 10:58:58","TRT02EDTM":"2022-02-18 16:58:58","AP01SDTM":"2020-01-01 08:23:21","AP01EDTM":"2021-02-18 10:58:58","AP02SDTM":"2021-02-18 10:58:58","AP02EDTM":"2022-02-18 16:58:58","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-16","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3982,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.46271,"AVALU":"U/L","BASE2":3.75505,"BASE":3.94495,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.70766,"PCHG2":418.30722,"CHG":15.51777,"PCHG":393.35822,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-03-02 08:23:21","ADY":426,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-327","SUBJID":"id-327","SITEID":"NGA-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.09908,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-01 08:23:21","TRTEDTM":"2022-02-18 16:58:58","TRT01SDTM":"2020-01-01 08:23:21","TRT01EDTM":"2021-02-18 10:58:58","TRT02SDTM":"2021-02-18 10:58:58","TRT02EDTM":"2022-02-18 16:58:58","AP01SDTM":"2020-01-01 08:23:21","AP01EDTM":"2021-02-18 10:58:58","AP02SDTM":"2021-02-18 10:58:58","AP02EDTM":"2022-02-18 16:58:58","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-16","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":332,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.77693,"AVALU":"U/L","BASE2":3.75505,"BASE":3.94495,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":28.02188,"PCHG2":746.2444,"CHG":27.83198,"PCHG":705.50997,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-03-21 08:23:21","ADY":445,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-327","SUBJID":"id-327","SITEID":"NGA-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.09908,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-01 08:23:21","TRTEDTM":"2022-02-18 16:58:58","TRT01SDTM":"2020-01-01 08:23:21","TRT01EDTM":"2021-02-18 10:58:58","TRT02SDTM":"2021-02-18 10:58:58","TRT02EDTM":"2022-02-18 16:58:58","AP01SDTM":"2020-01-01 08:23:21","AP01EDTM":"2021-02-18 10:58:58","AP02SDTM":"2021-02-18 10:58:58","AP02EDTM":"2022-02-18 16:58:58","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-16","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5414,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.17423,"AVALU":"U/L","BASE2":3.75505,"BASE":3.94495,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.41918,"PCHG2":410.62466,"CHG":15.22928,"PCHG":386.04548,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-11-02 08:23:21","ADY":671,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-327","SUBJID":"id-327","SITEID":"NGA-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.09908,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-01 08:23:21","TRTEDTM":"2022-02-18 16:58:58","TRT01SDTM":"2020-01-01 08:23:21","TRT01EDTM":"2021-02-18 10:58:58","TRT02SDTM":"2021-02-18 10:58:58","TRT02EDTM":"2022-02-18 16:58:58","AP01SDTM":"2020-01-01 08:23:21","AP01EDTM":"2021-02-18 10:58:58","AP02SDTM":"2021-02-18 10:58:58","AP02EDTM":"2022-02-18 16:58:58","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-16","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5920,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.68848,"AVALU":"mg/L","BASE2":10.68848,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"2","ADTM":"2020-03-18 08:23:21","ADY":77,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-327","SUBJID":"id-327","SITEID":"NGA-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.09908,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-01 08:23:21","TRTEDTM":"2022-02-18 16:58:58","TRT01SDTM":"2020-01-01 08:23:21","TRT01EDTM":"2021-02-18 10:58:58","TRT02SDTM":"2021-02-18 10:58:58","TRT02EDTM":"2022-02-18 16:58:58","AP01SDTM":"2020-01-01 08:23:21","AP01EDTM":"2021-02-18 10:58:58","AP02SDTM":"2021-02-18 10:58:58","AP02EDTM":"2022-02-18 16:58:58","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-16","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3466,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.1117,"AVALU":"mg/L","BASE2":10.68848,"BASE":10.1117,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.57678,"PCHG2":-5.39629,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2020-05-22 08:23:21","ADY":142,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-327","SUBJID":"id-327","SITEID":"NGA-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.09908,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-01 08:23:21","TRTEDTM":"2022-02-18 16:58:58","TRT01SDTM":"2020-01-01 08:23:21","TRT01EDTM":"2021-02-18 10:58:58","TRT02SDTM":"2021-02-18 10:58:58","TRT02EDTM":"2022-02-18 16:58:58","AP01SDTM":"2020-01-01 08:23:21","AP01EDTM":"2021-02-18 10:58:58","AP02SDTM":"2021-02-18 10:58:58","AP02EDTM":"2022-02-18 16:58:58","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-16","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3186,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.28757,"AVALU":"mg/L","BASE2":10.68848,"BASE":10.1117,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.40091,"PCHG2":-22.46258,"CHG":-1.82413,"PCHG":-18.03977,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2020-10-30 08:23:21","ADY":303,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-327","SUBJID":"id-327","SITEID":"NGA-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.09908,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-01 08:23:21","TRTEDTM":"2022-02-18 16:58:58","TRT01SDTM":"2020-01-01 08:23:21","TRT01EDTM":"2021-02-18 10:58:58","TRT02SDTM":"2021-02-18 10:58:58","TRT02EDTM":"2022-02-18 16:58:58","AP01SDTM":"2020-01-01 08:23:21","AP01EDTM":"2021-02-18 10:58:58","AP02SDTM":"2021-02-18 10:58:58","AP02EDTM":"2022-02-18 16:58:58","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-16","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1520,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.76605,"AVALU":"mg/L","BASE2":10.68848,"BASE":10.1117,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.92243,"PCHG2":-8.63018,"CHG":-0.34565,"PCHG":-3.41835,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-02-24 08:23:21","ADY":420,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-327","SUBJID":"id-327","SITEID":"NGA-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.09908,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-01 08:23:21","TRTEDTM":"2022-02-18 16:58:58","TRT01SDTM":"2020-01-01 08:23:21","TRT01EDTM":"2021-02-18 10:58:58","TRT02SDTM":"2021-02-18 10:58:58","TRT02EDTM":"2022-02-18 16:58:58","AP01SDTM":"2020-01-01 08:23:21","AP01EDTM":"2021-02-18 10:58:58","AP02SDTM":"2021-02-18 10:58:58","AP02EDTM":"2022-02-18 16:58:58","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-16","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":303,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.14366,"AVALU":"mg/L","BASE2":10.68848,"BASE":10.1117,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.54483,"PCHG2":-14.45319,"CHG":-0.96805,"PCHG":-9.57352,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-03-02 08:23:21","ADY":426,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-327","SUBJID":"id-327","SITEID":"NGA-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.09908,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-01 08:23:21","TRTEDTM":"2022-02-18 16:58:58","TRT01SDTM":"2020-01-01 08:23:21","TRT01EDTM":"2021-02-18 10:58:58","TRT02SDTM":"2021-02-18 10:58:58","TRT02EDTM":"2022-02-18 16:58:58","AP01SDTM":"2020-01-01 08:23:21","AP01EDTM":"2021-02-18 10:58:58","AP02SDTM":"2021-02-18 10:58:58","AP02EDTM":"2022-02-18 16:58:58","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-16","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7514,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.5129,"AVALU":"mg/L","BASE2":10.68848,"BASE":10.1117,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.17559,"PCHG2":-20.35449,"CHG":-1.59881,"PCHG":-15.81144,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-03-21 08:23:21","ADY":445,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-327","SUBJID":"id-327","SITEID":"NGA-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.09908,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-01 08:23:21","TRTEDTM":"2022-02-18 16:58:58","TRT01SDTM":"2020-01-01 08:23:21","TRT01EDTM":"2021-02-18 10:58:58","TRT02SDTM":"2021-02-18 10:58:58","TRT02EDTM":"2022-02-18 16:58:58","AP01SDTM":"2020-01-01 08:23:21","AP01EDTM":"2021-02-18 10:58:58","AP02SDTM":"2021-02-18 10:58:58","AP02EDTM":"2022-02-18 16:58:58","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-16","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6698,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.21254,"AVALU":"mg/L","BASE2":10.68848,"BASE":10.1117,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.47594,"PCHG2":-32.52045,"CHG":-2.89916,"PCHG":-28.67135,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-2","BTOXGR":"2","ADTM":"2021-11-02 08:23:21","ADY":671,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-327","SUBJID":"id-327","SITEID":"NGA-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.09908,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-01 08:23:21","TRTEDTM":"2022-02-18 16:58:58","TRT01SDTM":"2020-01-01 08:23:21","TRT01EDTM":"2021-02-18 10:58:58","TRT02SDTM":"2021-02-18 10:58:58","TRT02EDTM":"2022-02-18 16:58:58","AP01SDTM":"2020-01-01 08:23:21","AP01EDTM":"2021-02-18 10:58:58","AP02SDTM":"2021-02-18 10:58:58","AP02EDTM":"2022-02-18 16:58:58","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-16","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4799,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98284,"AVALU":"g/L","BASE2":2.98284,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-18 08:23:21","ADY":77,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-327","SUBJID":"id-327","SITEID":"NGA-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.09908,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-01 08:23:21","TRTEDTM":"2022-02-18 16:58:58","TRT01SDTM":"2020-01-01 08:23:21","TRT01EDTM":"2021-02-18 10:58:58","TRT02SDTM":"2021-02-18 10:58:58","TRT02EDTM":"2022-02-18 16:58:58","AP01SDTM":"2020-01-01 08:23:21","AP01EDTM":"2021-02-18 10:58:58","AP02SDTM":"2021-02-18 10:58:58","AP02EDTM":"2022-02-18 16:58:58","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-16","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4311,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91652,"AVALU":"g/L","BASE2":2.98284,"BASE":2.91652,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.06632,"PCHG2":-2.22335,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-22 08:23:21","ADY":142,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-327","SUBJID":"id-327","SITEID":"NGA-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.09908,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-01 08:23:21","TRTEDTM":"2022-02-18 16:58:58","TRT01SDTM":"2020-01-01 08:23:21","TRT01EDTM":"2021-02-18 10:58:58","TRT02SDTM":"2021-02-18 10:58:58","TRT02EDTM":"2022-02-18 16:58:58","AP01SDTM":"2020-01-01 08:23:21","AP01EDTM":"2021-02-18 10:58:58","AP02SDTM":"2021-02-18 10:58:58","AP02EDTM":"2022-02-18 16:58:58","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-16","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1580,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95662,"AVALU":"g/L","BASE2":2.98284,"BASE":2.91652,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02622,"PCHG2":-0.87899,"CHG":0.0401,"PCHG":1.37492,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-30 08:23:21","ADY":303,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-327","SUBJID":"id-327","SITEID":"NGA-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.09908,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-01 08:23:21","TRTEDTM":"2022-02-18 16:58:58","TRT01SDTM":"2020-01-01 08:23:21","TRT01EDTM":"2021-02-18 10:58:58","TRT02SDTM":"2021-02-18 10:58:58","TRT02EDTM":"2022-02-18 16:58:58","AP01SDTM":"2020-01-01 08:23:21","AP01EDTM":"2021-02-18 10:58:58","AP02SDTM":"2021-02-18 10:58:58","AP02EDTM":"2022-02-18 16:58:58","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-16","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4537,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.72392,"AVALU":"g/L","BASE2":2.98284,"BASE":2.91652,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.25892,"PCHG2":-8.68044,"CHG":-0.1926,"PCHG":-6.60392,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-24 08:23:21","ADY":420,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-327","SUBJID":"id-327","SITEID":"NGA-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.09908,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-01 08:23:21","TRTEDTM":"2022-02-18 16:58:58","TRT01SDTM":"2020-01-01 08:23:21","TRT01EDTM":"2021-02-18 10:58:58","TRT02SDTM":"2021-02-18 10:58:58","TRT02EDTM":"2022-02-18 16:58:58","AP01SDTM":"2020-01-01 08:23:21","AP01EDTM":"2021-02-18 10:58:58","AP02SDTM":"2021-02-18 10:58:58","AP02EDTM":"2022-02-18 16:58:58","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-16","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1958,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87404,"AVALU":"g/L","BASE2":2.98284,"BASE":2.91652,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1088,"PCHG2":-3.64738,"CHG":-0.04248,"PCHG":-1.45641,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-02 08:23:21","ADY":426,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-327","SUBJID":"id-327","SITEID":"NGA-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.09908,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-01 08:23:21","TRTEDTM":"2022-02-18 16:58:58","TRT01SDTM":"2020-01-01 08:23:21","TRT01EDTM":"2021-02-18 10:58:58","TRT02SDTM":"2021-02-18 10:58:58","TRT02EDTM":"2022-02-18 16:58:58","AP01SDTM":"2020-01-01 08:23:21","AP01EDTM":"2021-02-18 10:58:58","AP02SDTM":"2021-02-18 10:58:58","AP02EDTM":"2022-02-18 16:58:58","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-16","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7676,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99435,"AVALU":"g/L","BASE2":2.98284,"BASE":2.91652,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01151,"PCHG2":0.386,"CHG":0.07783,"PCHG":2.66868,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-21 08:23:21","ADY":445,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-327","SUBJID":"id-327","SITEID":"NGA-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.09908,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-01","TRTSDTM":"2020-01-01 08:23:21","TRTEDTM":"2022-02-18 16:58:58","TRT01SDTM":"2020-01-01 08:23:21","TRT01EDTM":"2021-02-18 10:58:58","TRT02SDTM":"2021-02-18 10:58:58","TRT02EDTM":"2022-02-18 16:58:58","AP01SDTM":"2020-01-01 08:23:21","AP01EDTM":"2021-02-18 10:58:58","AP02SDTM":"2021-02-18 10:58:58","AP02EDTM":"2022-02-18 16:58:58","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-16","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6456,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91803,"AVALU":"g/L","BASE2":2.98284,"BASE":2.91652,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06481,"PCHG2":-2.17261,"CHG":0.00151,"PCHG":0.0519,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-02 08:23:21","ADY":671,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-357","SUBJID":"id-357","SITEID":"NGA-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.82877,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-21 03:04:29","TRT01SDTM":"2020-01-21 03:04:29","AP01SDTM":"2020-01-21 03:04:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1223,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.69788,"AVALU":"U/L","BASE2":13.69788,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-15 03:04:29","ADY":360,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-357","SUBJID":"id-357","SITEID":"NGA-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.82877,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-21 03:04:29","TRT01SDTM":"2020-01-21 03:04:29","AP01SDTM":"2020-01-21 03:04:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3772,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.12686,"AVALU":"U/L","BASE2":13.69788,"BASE":33.12686,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":19.42898,"PCHG2":141.83927,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-01 03:04:29","ADY":405,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-357","SUBJID":"id-357","SITEID":"NGA-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.82877,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-21 03:04:29","TRT01SDTM":"2020-01-21 03:04:29","AP01SDTM":"2020-01-21 03:04:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6738,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.56285,"AVALU":"U/L","BASE2":13.69788,"BASE":33.12686,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13503,"PCHG2":-0.98578,"CHG":-19.56401,"PCHG":-59.05784,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-08 03:04:29","ADY":443,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-357","SUBJID":"id-357","SITEID":"NGA-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.82877,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-21 03:04:29","TRT01SDTM":"2020-01-21 03:04:29","AP01SDTM":"2020-01-21 03:04:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":914,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.9726,"AVALU":"U/L","BASE2":13.69788,"BASE":33.12686,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.27472,"PCHG2":2.00553,"CHG":-19.15426,"PCHG":-57.82094,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-29 03:04:29","ADY":647,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-357","SUBJID":"id-357","SITEID":"NGA-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.82877,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-21 03:04:29","TRT01SDTM":"2020-01-21 03:04:29","AP01SDTM":"2020-01-21 03:04:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1535,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.72644,"AVALU":"U/L","BASE2":13.69788,"BASE":33.12686,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.97144,"PCHG2":-50.89432,"CHG":-26.40042,"PCHG":-79.69491,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-11-25 03:04:29","ADY":674,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-357","SUBJID":"id-357","SITEID":"NGA-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.82877,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-21 03:04:29","TRT01SDTM":"2020-01-21 03:04:29","AP01SDTM":"2020-01-21 03:04:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4541,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.13907,"AVALU":"U/L","BASE2":13.69788,"BASE":33.12686,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.44118,"PCHG2":3.22081,"CHG":-18.98779,"PCHG":-57.31842,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-11 03:04:29","ADY":690,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-357","SUBJID":"id-357","SITEID":"NGA-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.82877,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-21 03:04:29","TRT01SDTM":"2020-01-21 03:04:29","AP01SDTM":"2020-01-21 03:04:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3432,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.13758,"AVALU":"U/L","BASE2":13.69788,"BASE":33.12686,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.43969,"PCHG2":120.01632,"CHG":-2.98928,"PCHG":-9.02374,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-24 03:04:29","ADY":703,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-357","SUBJID":"id-357","SITEID":"NGA-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.82877,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-21 03:04:29","TRT01SDTM":"2020-01-21 03:04:29","AP01SDTM":"2020-01-21 03:04:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1082,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.41603,"AVALU":"mg/L","BASE2":8.41603,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-15 03:04:29","ADY":360,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-357","SUBJID":"id-357","SITEID":"NGA-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.82877,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-21 03:04:29","TRT01SDTM":"2020-01-21 03:04:29","AP01SDTM":"2020-01-21 03:04:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5035,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.87902,"AVALU":"mg/L","BASE2":8.41603,"BASE":9.87902,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.46299,"PCHG2":17.3834,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-01 03:04:29","ADY":405,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-357","SUBJID":"id-357","SITEID":"NGA-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.82877,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-21 03:04:29","TRT01SDTM":"2020-01-21 03:04:29","AP01SDTM":"2020-01-21 03:04:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1556,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.53472,"AVALU":"mg/L","BASE2":8.41603,"BASE":9.87902,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11869,"PCHG2":1.41027,"CHG":-1.3443,"PCHG":-13.60766,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-08 03:04:29","ADY":443,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-357","SUBJID":"id-357","SITEID":"NGA-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.82877,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-21 03:04:29","TRT01SDTM":"2020-01-21 03:04:29","AP01SDTM":"2020-01-21 03:04:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8351,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.77697,"AVALU":"mg/L","BASE2":8.41603,"BASE":9.87902,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.36094,"PCHG2":4.28871,"CHG":-1.10205,"PCHG":-11.15549,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-29 03:04:29","ADY":647,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-357","SUBJID":"id-357","SITEID":"NGA-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.82877,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-21 03:04:29","TRT01SDTM":"2020-01-21 03:04:29","AP01SDTM":"2020-01-21 03:04:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5775,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.35425,"AVALU":"mg/L","BASE2":8.41603,"BASE":9.87902,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.93823,"PCHG2":11.14809,"CHG":-0.52477,"PCHG":-5.31192,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-25 03:04:29","ADY":674,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-357","SUBJID":"id-357","SITEID":"NGA-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.82877,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-21 03:04:29","TRT01SDTM":"2020-01-21 03:04:29","AP01SDTM":"2020-01-21 03:04:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":712,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.75715,"AVALU":"mg/L","BASE2":8.41603,"BASE":9.87902,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.34112,"PCHG2":4.05324,"CHG":-1.12187,"PCHG":-11.35609,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-11 03:04:29","ADY":690,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-357","SUBJID":"id-357","SITEID":"NGA-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.82877,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-21 03:04:29","TRT01SDTM":"2020-01-21 03:04:29","AP01SDTM":"2020-01-21 03:04:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3328,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.75521,"AVALU":"mg/L","BASE2":8.41603,"BASE":9.87902,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.33919,"PCHG2":4.03023,"CHG":-1.12381,"PCHG":-11.37569,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-24 03:04:29","ADY":703,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-357","SUBJID":"id-357","SITEID":"NGA-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.82877,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-21 03:04:29","TRT01SDTM":"2020-01-21 03:04:29","AP01SDTM":"2020-01-21 03:04:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4238,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87114,"AVALU":"g/L","BASE2":2.87114,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-01-15 03:04:29","ADY":360,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-357","SUBJID":"id-357","SITEID":"NGA-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.82877,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-21 03:04:29","TRT01SDTM":"2020-01-21 03:04:29","AP01SDTM":"2020-01-21 03:04:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2225,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.06073,"AVALU":"g/L","BASE2":2.87114,"BASE":3.06073,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.18959,"PCHG2":6.60326,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2021-03-01 03:04:29","ADY":405,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-357","SUBJID":"id-357","SITEID":"NGA-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.82877,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-21 03:04:29","TRT01SDTM":"2020-01-21 03:04:29","AP01SDTM":"2020-01-21 03:04:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4073,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97428,"AVALU":"g/L","BASE2":2.87114,"BASE":3.06073,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10314,"PCHG2":3.59214,"CHG":-0.08645,"PCHG":-2.8246,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-04-08 03:04:29","ADY":443,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-357","SUBJID":"id-357","SITEID":"NGA-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.82877,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-21 03:04:29","TRT01SDTM":"2020-01-21 03:04:29","AP01SDTM":"2020-01-21 03:04:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3223,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97116,"AVALU":"g/L","BASE2":2.87114,"BASE":3.06073,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10002,"PCHG2":3.48371,"CHG":-0.08957,"PCHG":-2.92631,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-10-29 03:04:29","ADY":647,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-357","SUBJID":"id-357","SITEID":"NGA-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.82877,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-21 03:04:29","TRT01SDTM":"2020-01-21 03:04:29","AP01SDTM":"2020-01-21 03:04:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1783,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.69375,"AVALU":"g/L","BASE2":2.87114,"BASE":3.06073,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1774,"PCHG2":-6.17859,"CHG":-0.36698,"PCHG":-11.99011,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-11-25 03:04:29","ADY":674,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-357","SUBJID":"id-357","SITEID":"NGA-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.82877,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-21 03:04:29","TRT01SDTM":"2020-01-21 03:04:29","AP01SDTM":"2020-01-21 03:04:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1155,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84199,"AVALU":"g/L","BASE2":2.87114,"BASE":3.06073,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02915,"PCHG2":-1.01537,"CHG":-0.21874,"PCHG":-7.14671,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-12-11 03:04:29","ADY":690,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-357","SUBJID":"id-357","SITEID":"NGA-1","AGE":41,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.82877,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-21 03:04:29","TRT01SDTM":"2020-01-21 03:04:29","AP01SDTM":"2020-01-21 03:04:29","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8157,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80658,"AVALU":"g/L","BASE2":2.87114,"BASE":3.06073,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06457,"PCHG2":-2.24884,"CHG":-0.25416,"PCHG":-8.30378,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-12-24 03:04:29","ADY":703,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-388","SUBJID":"id-388","SITEID":"NGA-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-17","TRTSDTM":"2019-05-17 15:03:20","TRTEDTM":"2022-02-15 07:04:01","TRT01SDTM":"2019-05-17 15:03:20","TRT01EDTM":"2021-02-15 01:04:01","TRT02SDTM":"2021-02-15 01:04:01","TRT02EDTM":"2022-02-15 07:04:01","AP01SDTM":"2019-05-17 15:03:20","AP01EDTM":"2021-02-15 01:04:01","AP02SDTM":"2021-02-15 01:04:01","AP02EDTM":"2022-02-15 07:04:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1005,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-11","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5026,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.11244,"AVALU":"U/L","BASE2":11.11244,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-01-02 15:03:20","ADY":230,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-388","SUBJID":"id-388","SITEID":"NGA-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-17","TRTSDTM":"2019-05-17 15:03:20","TRTEDTM":"2022-02-15 07:04:01","TRT01SDTM":"2019-05-17 15:03:20","TRT01EDTM":"2021-02-15 01:04:01","TRT02SDTM":"2021-02-15 01:04:01","TRT02EDTM":"2022-02-15 07:04:01","AP01SDTM":"2019-05-17 15:03:20","AP01EDTM":"2021-02-15 01:04:01","AP02SDTM":"2021-02-15 01:04:01","AP02EDTM":"2022-02-15 07:04:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1005,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-11","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5164,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.63946,"AVALU":"U/L","BASE2":11.11244,"BASE":4.63946,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-6.47298,"PCHG2":-58.24984,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2020-03-29 15:03:20","ADY":317,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-388","SUBJID":"id-388","SITEID":"NGA-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-17","TRTSDTM":"2019-05-17 15:03:20","TRTEDTM":"2022-02-15 07:04:01","TRT01SDTM":"2019-05-17 15:03:20","TRT01EDTM":"2021-02-15 01:04:01","TRT02SDTM":"2021-02-15 01:04:01","TRT02EDTM":"2022-02-15 07:04:01","AP01SDTM":"2019-05-17 15:03:20","AP01EDTM":"2021-02-15 01:04:01","AP02SDTM":"2021-02-15 01:04:01","AP02EDTM":"2022-02-15 07:04:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1005,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-11","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1990,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.30231,"AVALU":"U/L","BASE2":11.11244,"BASE":4.63946,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.18986,"PCHG2":145.69131,"CHG":22.66284,"PCHG":488.47996,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-06-20 15:03:20","ADY":400,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-388","SUBJID":"id-388","SITEID":"NGA-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-17","TRTSDTM":"2019-05-17 15:03:20","TRTEDTM":"2022-02-15 07:04:01","TRT01SDTM":"2019-05-17 15:03:20","TRT01EDTM":"2021-02-15 01:04:01","TRT02SDTM":"2021-02-15 01:04:01","TRT02EDTM":"2022-02-15 07:04:01","AP01SDTM":"2019-05-17 15:03:20","AP01EDTM":"2021-02-15 01:04:01","AP02SDTM":"2021-02-15 01:04:01","AP02EDTM":"2022-02-15 07:04:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1005,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-11","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3675,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.25555,"AVALU":"U/L","BASE2":11.11244,"BASE":4.63946,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.14311,"PCHG2":100.27593,"CHG":17.61609,"PCHG":379.70101,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-07-27 15:03:20","ADY":437,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-388","SUBJID":"id-388","SITEID":"NGA-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-17","TRTSDTM":"2019-05-17 15:03:20","TRTEDTM":"2022-02-15 07:04:01","TRT01SDTM":"2019-05-17 15:03:20","TRT01EDTM":"2021-02-15 01:04:01","TRT02SDTM":"2021-02-15 01:04:01","TRT02EDTM":"2022-02-15 07:04:01","AP01SDTM":"2019-05-17 15:03:20","AP01EDTM":"2021-02-15 01:04:01","AP02SDTM":"2021-02-15 01:04:01","AP02EDTM":"2022-02-15 07:04:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1005,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-11","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4105,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.22356,"AVALU":"U/L","BASE2":11.11244,"BASE":4.63946,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.11111,"PCHG2":27.99668,"CHG":9.5841,"PCHG":206.5777,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-10-15 15:03:20","ADY":517,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-388","SUBJID":"id-388","SITEID":"NGA-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-17","TRTSDTM":"2019-05-17 15:03:20","TRTEDTM":"2022-02-15 07:04:01","TRT01SDTM":"2019-05-17 15:03:20","TRT01EDTM":"2021-02-15 01:04:01","TRT02SDTM":"2021-02-15 01:04:01","TRT02EDTM":"2022-02-15 07:04:01","AP01SDTM":"2019-05-17 15:03:20","AP01EDTM":"2021-02-15 01:04:01","AP02SDTM":"2021-02-15 01:04:01","AP02EDTM":"2022-02-15 07:04:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1005,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-11","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6526,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.81639,"AVALU":"U/L","BASE2":11.11244,"BASE":4.63946,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.70394,"PCHG2":15.33365,"CHG":8.17692,"PCHG":176.24721,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-11-22 15:03:20","ADY":555,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-388","SUBJID":"id-388","SITEID":"NGA-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-17","TRTSDTM":"2019-05-17 15:03:20","TRTEDTM":"2022-02-15 07:04:01","TRT01SDTM":"2019-05-17 15:03:20","TRT01EDTM":"2021-02-15 01:04:01","TRT02SDTM":"2021-02-15 01:04:01","TRT02EDTM":"2022-02-15 07:04:01","AP01SDTM":"2019-05-17 15:03:20","AP01EDTM":"2021-02-15 01:04:01","AP02SDTM":"2021-02-15 01:04:01","AP02EDTM":"2022-02-15 07:04:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1005,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-11","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4169,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.48374,"AVALU":"U/L","BASE2":11.11244,"BASE":4.63946,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.3713,"PCHG2":57.33484,"CHG":12.84428,"PCHG":276.8485,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-04-21 15:03:20","ADY":705,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-388","SUBJID":"id-388","SITEID":"NGA-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-17","TRTSDTM":"2019-05-17 15:03:20","TRTEDTM":"2022-02-15 07:04:01","TRT01SDTM":"2019-05-17 15:03:20","TRT01EDTM":"2021-02-15 01:04:01","TRT02SDTM":"2021-02-15 01:04:01","TRT02EDTM":"2022-02-15 07:04:01","AP01SDTM":"2019-05-17 15:03:20","AP01EDTM":"2021-02-15 01:04:01","AP02SDTM":"2021-02-15 01:04:01","AP02EDTM":"2022-02-15 07:04:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1005,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-11","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4679,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.57471,"AVALU":"mg/L","BASE2":8.57471,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-02 15:03:20","ADY":230,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-388","SUBJID":"id-388","SITEID":"NGA-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-17","TRTSDTM":"2019-05-17 15:03:20","TRTEDTM":"2022-02-15 07:04:01","TRT01SDTM":"2019-05-17 15:03:20","TRT01EDTM":"2021-02-15 01:04:01","TRT02SDTM":"2021-02-15 01:04:01","TRT02EDTM":"2022-02-15 07:04:01","AP01SDTM":"2019-05-17 15:03:20","AP01EDTM":"2021-02-15 01:04:01","AP02SDTM":"2021-02-15 01:04:01","AP02EDTM":"2022-02-15 07:04:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1005,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-11","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3687,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.81084,"AVALU":"mg/L","BASE2":8.57471,"BASE":8.81084,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.23613,"PCHG2":2.75379,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-29 15:03:20","ADY":317,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-388","SUBJID":"id-388","SITEID":"NGA-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-17","TRTSDTM":"2019-05-17 15:03:20","TRTEDTM":"2022-02-15 07:04:01","TRT01SDTM":"2019-05-17 15:03:20","TRT01EDTM":"2021-02-15 01:04:01","TRT02SDTM":"2021-02-15 01:04:01","TRT02EDTM":"2022-02-15 07:04:01","AP01SDTM":"2019-05-17 15:03:20","AP01EDTM":"2021-02-15 01:04:01","AP02SDTM":"2021-02-15 01:04:01","AP02EDTM":"2022-02-15 07:04:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1005,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-11","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3382,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.41702,"AVALU":"mg/L","BASE2":8.57471,"BASE":8.81084,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.84231,"PCHG2":21.48535,"CHG":1.60618,"PCHG":18.22956,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-06-20 15:03:20","ADY":400,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-388","SUBJID":"id-388","SITEID":"NGA-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-17","TRTSDTM":"2019-05-17 15:03:20","TRTEDTM":"2022-02-15 07:04:01","TRT01SDTM":"2019-05-17 15:03:20","TRT01EDTM":"2021-02-15 01:04:01","TRT02SDTM":"2021-02-15 01:04:01","TRT02EDTM":"2022-02-15 07:04:01","AP01SDTM":"2019-05-17 15:03:20","AP01EDTM":"2021-02-15 01:04:01","AP02SDTM":"2021-02-15 01:04:01","AP02EDTM":"2022-02-15 07:04:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1005,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-11","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1186,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.12911,"AVALU":"mg/L","BASE2":8.57471,"BASE":8.81084,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.4456,"PCHG2":-5.19669,"CHG":-0.68173,"PCHG":-7.7374,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-27 15:03:20","ADY":437,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-388","SUBJID":"id-388","SITEID":"NGA-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-17","TRTSDTM":"2019-05-17 15:03:20","TRTEDTM":"2022-02-15 07:04:01","TRT01SDTM":"2019-05-17 15:03:20","TRT01EDTM":"2021-02-15 01:04:01","TRT02SDTM":"2021-02-15 01:04:01","TRT02EDTM":"2022-02-15 07:04:01","AP01SDTM":"2019-05-17 15:03:20","AP01EDTM":"2021-02-15 01:04:01","AP02SDTM":"2021-02-15 01:04:01","AP02EDTM":"2022-02-15 07:04:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1005,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-11","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6771,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.32904,"AVALU":"mg/L","BASE2":8.57471,"BASE":8.81084,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.24567,"PCHG2":-2.86505,"CHG":-0.4818,"PCHG":-5.46825,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-15 15:03:20","ADY":517,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-388","SUBJID":"id-388","SITEID":"NGA-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-17","TRTSDTM":"2019-05-17 15:03:20","TRTEDTM":"2022-02-15 07:04:01","TRT01SDTM":"2019-05-17 15:03:20","TRT01EDTM":"2021-02-15 01:04:01","TRT02SDTM":"2021-02-15 01:04:01","TRT02EDTM":"2022-02-15 07:04:01","AP01SDTM":"2019-05-17 15:03:20","AP01EDTM":"2021-02-15 01:04:01","AP02SDTM":"2021-02-15 01:04:01","AP02EDTM":"2022-02-15 07:04:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1005,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-11","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2037,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.11545,"AVALU":"mg/L","BASE2":8.57471,"BASE":8.81084,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.54074,"PCHG2":6.30621,"CHG":0.30461,"PCHG":3.45722,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-22 15:03:20","ADY":555,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-388","SUBJID":"id-388","SITEID":"NGA-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-17","TRTSDTM":"2019-05-17 15:03:20","TRTEDTM":"2022-02-15 07:04:01","TRT01SDTM":"2019-05-17 15:03:20","TRT01EDTM":"2021-02-15 01:04:01","TRT02SDTM":"2021-02-15 01:04:01","TRT02EDTM":"2022-02-15 07:04:01","AP01SDTM":"2019-05-17 15:03:20","AP01EDTM":"2021-02-15 01:04:01","AP02SDTM":"2021-02-15 01:04:01","AP02EDTM":"2022-02-15 07:04:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1005,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-11","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5611,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.82658,"AVALU":"mg/L","BASE2":8.57471,"BASE":8.81084,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.25187,"PCHG2":2.93734,"CHG":0.01574,"PCHG":0.17864,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-21 15:03:20","ADY":705,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-388","SUBJID":"id-388","SITEID":"NGA-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-17","TRTSDTM":"2019-05-17 15:03:20","TRTEDTM":"2022-02-15 07:04:01","TRT01SDTM":"2019-05-17 15:03:20","TRT01EDTM":"2021-02-15 01:04:01","TRT02SDTM":"2021-02-15 01:04:01","TRT02EDTM":"2022-02-15 07:04:01","AP01SDTM":"2019-05-17 15:03:20","AP01EDTM":"2021-02-15 01:04:01","AP02SDTM":"2021-02-15 01:04:01","AP02EDTM":"2022-02-15 07:04:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1005,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-11","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3049,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75773,"AVALU":"g/L","BASE2":2.75773,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-02 15:03:20","ADY":230,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-388","SUBJID":"id-388","SITEID":"NGA-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-17","TRTSDTM":"2019-05-17 15:03:20","TRTEDTM":"2022-02-15 07:04:01","TRT01SDTM":"2019-05-17 15:03:20","TRT01EDTM":"2021-02-15 01:04:01","TRT02SDTM":"2021-02-15 01:04:01","TRT02EDTM":"2022-02-15 07:04:01","AP01SDTM":"2019-05-17 15:03:20","AP01EDTM":"2021-02-15 01:04:01","AP02SDTM":"2021-02-15 01:04:01","AP02EDTM":"2022-02-15 07:04:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1005,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-11","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6332,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87769,"AVALU":"g/L","BASE2":2.75773,"BASE":2.87769,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.11996,"PCHG2":4.34983,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-29 15:03:20","ADY":317,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-388","SUBJID":"id-388","SITEID":"NGA-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-17","TRTSDTM":"2019-05-17 15:03:20","TRTEDTM":"2022-02-15 07:04:01","TRT01SDTM":"2019-05-17 15:03:20","TRT01EDTM":"2021-02-15 01:04:01","TRT02SDTM":"2021-02-15 01:04:01","TRT02EDTM":"2022-02-15 07:04:01","AP01SDTM":"2019-05-17 15:03:20","AP01EDTM":"2021-02-15 01:04:01","AP02SDTM":"2021-02-15 01:04:01","AP02EDTM":"2022-02-15 07:04:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1005,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-11","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4591,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91613,"AVALU":"g/L","BASE2":2.75773,"BASE":2.87769,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1584,"PCHG2":5.74367,"CHG":0.03844,"PCHG":1.33574,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-20 15:03:20","ADY":400,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-388","SUBJID":"id-388","SITEID":"NGA-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-17","TRTSDTM":"2019-05-17 15:03:20","TRTEDTM":"2022-02-15 07:04:01","TRT01SDTM":"2019-05-17 15:03:20","TRT01EDTM":"2021-02-15 01:04:01","TRT02SDTM":"2021-02-15 01:04:01","TRT02EDTM":"2022-02-15 07:04:01","AP01SDTM":"2019-05-17 15:03:20","AP01EDTM":"2021-02-15 01:04:01","AP02SDTM":"2021-02-15 01:04:01","AP02EDTM":"2022-02-15 07:04:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1005,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-11","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7900,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91456,"AVALU":"g/L","BASE2":2.75773,"BASE":2.87769,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15683,"PCHG2":5.68677,"CHG":0.03687,"PCHG":1.28121,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-27 15:03:20","ADY":437,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-388","SUBJID":"id-388","SITEID":"NGA-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-17","TRTSDTM":"2019-05-17 15:03:20","TRTEDTM":"2022-02-15 07:04:01","TRT01SDTM":"2019-05-17 15:03:20","TRT01EDTM":"2021-02-15 01:04:01","TRT02SDTM":"2021-02-15 01:04:01","TRT02EDTM":"2022-02-15 07:04:01","AP01SDTM":"2019-05-17 15:03:20","AP01EDTM":"2021-02-15 01:04:01","AP02SDTM":"2021-02-15 01:04:01","AP02EDTM":"2022-02-15 07:04:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1005,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-11","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4011,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0108,"AVALU":"g/L","BASE2":2.75773,"BASE":2.87769,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.25306,"PCHG2":9.17647,"CHG":0.13311,"PCHG":4.62545,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-10-15 15:03:20","ADY":517,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-388","SUBJID":"id-388","SITEID":"NGA-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-17","TRTSDTM":"2019-05-17 15:03:20","TRTEDTM":"2022-02-15 07:04:01","TRT01SDTM":"2019-05-17 15:03:20","TRT01EDTM":"2021-02-15 01:04:01","TRT02SDTM":"2021-02-15 01:04:01","TRT02EDTM":"2022-02-15 07:04:01","AP01SDTM":"2019-05-17 15:03:20","AP01EDTM":"2021-02-15 01:04:01","AP02SDTM":"2021-02-15 01:04:01","AP02EDTM":"2022-02-15 07:04:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1005,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-11","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2892,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80446,"AVALU":"g/L","BASE2":2.75773,"BASE":2.87769,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04673,"PCHG2":1.69447,"CHG":-0.07323,"PCHG":-2.54466,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-22 15:03:20","ADY":555,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-388","SUBJID":"id-388","SITEID":"NGA-1","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-17","TRTSDTM":"2019-05-17 15:03:20","TRTEDTM":"2022-02-15 07:04:01","TRT01SDTM":"2019-05-17 15:03:20","TRT01EDTM":"2021-02-15 01:04:01","TRT02SDTM":"2021-02-15 01:04:01","TRT02EDTM":"2022-02-15 07:04:01","AP01SDTM":"2019-05-17 15:03:20","AP01EDTM":"2021-02-15 01:04:01","AP02SDTM":"2021-02-15 01:04:01","AP02EDTM":"2022-02-15 07:04:01","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1005,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-11","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4665,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01766,"AVALU":"g/L","BASE2":2.75773,"BASE":2.87769,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.25993,"PCHG2":9.42551,"CHG":0.13997,"PCHG":4.8641,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-04-21 15:03:20","ADY":705,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-43","SUBJID":"id-43","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":5.08774,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-08","TRTSDTM":"2020-09-10 03:20:32","TRTEDTM":"2023-09-10 21:20:32","TRT01SDTM":"2020-09-10 03:20:32","TRT01EDTM":"2022-09-10 15:20:32","TRT02SDTM":"2022-09-10 15:20:32","TRT02EDTM":"2023-09-10 21:20:32","AP01SDTM":"2020-09-10 03:20:32","AP01EDTM":"2022-09-10 15:20:32","AP02SDTM":"2022-09-10 15:20:32","AP02EDTM":"2023-09-10 21:20:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-22","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5429,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.45863,"AVALU":"U/L","BASE2":13.45863,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-03-24 03:20:32","ADY":195,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-43","SUBJID":"id-43","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":5.08774,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-08","TRTSDTM":"2020-09-10 03:20:32","TRTEDTM":"2023-09-10 21:20:32","TRT01SDTM":"2020-09-10 03:20:32","TRT01EDTM":"2022-09-10 15:20:32","TRT02SDTM":"2022-09-10 15:20:32","TRT02EDTM":"2023-09-10 21:20:32","AP01SDTM":"2020-09-10 03:20:32","AP01EDTM":"2022-09-10 15:20:32","AP02SDTM":"2022-09-10 15:20:32","AP02EDTM":"2023-09-10 21:20:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-22","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1174,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.89858,"AVALU":"U/L","BASE2":13.45863,"BASE":5.89858,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-7.56005,"PCHG2":-56.1725,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2021-07-13 03:20:32","ADY":306,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-43","SUBJID":"id-43","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":5.08774,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-08","TRTSDTM":"2020-09-10 03:20:32","TRTEDTM":"2023-09-10 21:20:32","TRT01SDTM":"2020-09-10 03:20:32","TRT01EDTM":"2022-09-10 15:20:32","TRT02SDTM":"2022-09-10 15:20:32","TRT02EDTM":"2023-09-10 21:20:32","AP01SDTM":"2020-09-10 03:20:32","AP01EDTM":"2022-09-10 15:20:32","AP02SDTM":"2022-09-10 15:20:32","AP02EDTM":"2023-09-10 21:20:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-22","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1078,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":44.74871,"AVALU":"U/L","BASE2":13.45863,"BASE":5.89858,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":31.29008,"PCHG2":232.49079,"CHG":38.85013,"PCHG":658.63512,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-02-16 03:20:32","ADY":524,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-43","SUBJID":"id-43","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":5.08774,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-08","TRTSDTM":"2020-09-10 03:20:32","TRTEDTM":"2023-09-10 21:20:32","TRT01SDTM":"2020-09-10 03:20:32","TRT01EDTM":"2022-09-10 15:20:32","TRT02SDTM":"2022-09-10 15:20:32","TRT02EDTM":"2023-09-10 21:20:32","AP01SDTM":"2020-09-10 03:20:32","AP01EDTM":"2022-09-10 15:20:32","AP02SDTM":"2022-09-10 15:20:32","AP02EDTM":"2023-09-10 21:20:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-22","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7494,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.45833,"AVALU":"U/L","BASE2":13.45863,"BASE":5.89858,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.9997,"PCHG2":37.14868,"CHG":12.55975,"PCHG":212.92837,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-07-10 03:20:32","ADY":668,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-43","SUBJID":"id-43","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":5.08774,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-08","TRTSDTM":"2020-09-10 03:20:32","TRTEDTM":"2023-09-10 21:20:32","TRT01SDTM":"2020-09-10 03:20:32","TRT01EDTM":"2022-09-10 15:20:32","TRT02SDTM":"2022-09-10 15:20:32","TRT02EDTM":"2023-09-10 21:20:32","AP01SDTM":"2020-09-10 03:20:32","AP01EDTM":"2022-09-10 15:20:32","AP02SDTM":"2022-09-10 15:20:32","AP02EDTM":"2023-09-10 21:20:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-22","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1210,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.08633,"AVALU":"U/L","BASE2":13.45863,"BASE":5.89858,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.6277,"PCHG2":71.53552,"CHG":17.18775,"PCHG":291.3879,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-11-11 03:20:32","ADY":792,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-43","SUBJID":"id-43","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":5.08774,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-08","TRTSDTM":"2020-09-10 03:20:32","TRTEDTM":"2023-09-10 21:20:32","TRT01SDTM":"2020-09-10 03:20:32","TRT01EDTM":"2022-09-10 15:20:32","TRT02SDTM":"2022-09-10 15:20:32","TRT02EDTM":"2023-09-10 21:20:32","AP01SDTM":"2020-09-10 03:20:32","AP01EDTM":"2022-09-10 15:20:32","AP02SDTM":"2022-09-10 15:20:32","AP02EDTM":"2023-09-10 21:20:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-22","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8000,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.36839,"AVALU":"U/L","BASE2":13.45863,"BASE":5.89858,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.90976,"PCHG2":66.2011,"CHG":16.46981,"PCHG":279.21649,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2023-02-24 03:20:32","ADY":897,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-43","SUBJID":"id-43","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":5.08774,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-08","TRTSDTM":"2020-09-10 03:20:32","TRTEDTM":"2023-09-10 21:20:32","TRT01SDTM":"2020-09-10 03:20:32","TRT01EDTM":"2022-09-10 15:20:32","TRT02SDTM":"2022-09-10 15:20:32","TRT02EDTM":"2023-09-10 21:20:32","AP01SDTM":"2020-09-10 03:20:32","AP01EDTM":"2022-09-10 15:20:32","AP02SDTM":"2022-09-10 15:20:32","AP02EDTM":"2023-09-10 21:20:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-22","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6515,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.64352,"AVALU":"U/L","BASE2":13.45863,"BASE":5.89858,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.18489,"PCHG2":53.385,"CHG":14.74494,"PCHG":249.97434,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2023-07-16 03:20:32","ADY":1039,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-43","SUBJID":"id-43","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":5.08774,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-08","TRTSDTM":"2020-09-10 03:20:32","TRTEDTM":"2023-09-10 21:20:32","TRT01SDTM":"2020-09-10 03:20:32","TRT01EDTM":"2022-09-10 15:20:32","TRT02SDTM":"2022-09-10 15:20:32","TRT02EDTM":"2023-09-10 21:20:32","AP01SDTM":"2020-09-10 03:20:32","AP01EDTM":"2022-09-10 15:20:32","AP02SDTM":"2022-09-10 15:20:32","AP02EDTM":"2023-09-10 21:20:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-22","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4252,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.81996,"AVALU":"mg/L","BASE2":7.81996,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-03-24 03:20:32","ADY":195,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-43","SUBJID":"id-43","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":5.08774,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-08","TRTSDTM":"2020-09-10 03:20:32","TRTEDTM":"2023-09-10 21:20:32","TRT01SDTM":"2020-09-10 03:20:32","TRT01EDTM":"2022-09-10 15:20:32","TRT02SDTM":"2022-09-10 15:20:32","TRT02EDTM":"2023-09-10 21:20:32","AP01SDTM":"2020-09-10 03:20:32","AP01EDTM":"2022-09-10 15:20:32","AP02SDTM":"2022-09-10 15:20:32","AP02EDTM":"2023-09-10 21:20:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-22","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7349,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.721,"AVALU":"mg/L","BASE2":7.81996,"BASE":8.721,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.90104,"PCHG2":11.52231,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-13 03:20:32","ADY":306,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-43","SUBJID":"id-43","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":5.08774,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-08","TRTSDTM":"2020-09-10 03:20:32","TRTEDTM":"2023-09-10 21:20:32","TRT01SDTM":"2020-09-10 03:20:32","TRT01EDTM":"2022-09-10 15:20:32","TRT02SDTM":"2022-09-10 15:20:32","TRT02EDTM":"2023-09-10 21:20:32","AP01SDTM":"2020-09-10 03:20:32","AP01EDTM":"2022-09-10 15:20:32","AP02SDTM":"2022-09-10 15:20:32","AP02EDTM":"2023-09-10 21:20:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-22","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7073,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.99066,"AVALU":"mg/L","BASE2":7.81996,"BASE":8.721,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17071,"PCHG2":2.18295,"CHG":-0.73033,"PCHG":-8.37443,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-02-16 03:20:32","ADY":524,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-43","SUBJID":"id-43","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":5.08774,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-08","TRTSDTM":"2020-09-10 03:20:32","TRTEDTM":"2023-09-10 21:20:32","TRT01SDTM":"2020-09-10 03:20:32","TRT01EDTM":"2022-09-10 15:20:32","TRT02SDTM":"2022-09-10 15:20:32","TRT02EDTM":"2023-09-10 21:20:32","AP01SDTM":"2020-09-10 03:20:32","AP01EDTM":"2022-09-10 15:20:32","AP02SDTM":"2022-09-10 15:20:32","AP02EDTM":"2023-09-10 21:20:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-22","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1996,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.44651,"AVALU":"mg/L","BASE2":7.81996,"BASE":8.721,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.62656,"PCHG2":20.80007,"CHG":0.72552,"PCHG":8.31919,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-10 03:20:32","ADY":668,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-43","SUBJID":"id-43","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":5.08774,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-08","TRTSDTM":"2020-09-10 03:20:32","TRTEDTM":"2023-09-10 21:20:32","TRT01SDTM":"2020-09-10 03:20:32","TRT01EDTM":"2022-09-10 15:20:32","TRT02SDTM":"2022-09-10 15:20:32","TRT02EDTM":"2023-09-10 21:20:32","AP01SDTM":"2020-09-10 03:20:32","AP01EDTM":"2022-09-10 15:20:32","AP02SDTM":"2022-09-10 15:20:32","AP02EDTM":"2023-09-10 21:20:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-22","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":351,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.36907,"AVALU":"mg/L","BASE2":7.81996,"BASE":8.721,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.54912,"PCHG2":32.59757,"CHG":1.64808,"PCHG":18.8978,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-11-11 03:20:32","ADY":792,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-43","SUBJID":"id-43","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":5.08774,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-08","TRTSDTM":"2020-09-10 03:20:32","TRTEDTM":"2023-09-10 21:20:32","TRT01SDTM":"2020-09-10 03:20:32","TRT01EDTM":"2022-09-10 15:20:32","TRT02SDTM":"2022-09-10 15:20:32","TRT02EDTM":"2023-09-10 21:20:32","AP01SDTM":"2020-09-10 03:20:32","AP01EDTM":"2022-09-10 15:20:32","AP02SDTM":"2022-09-10 15:20:32","AP02EDTM":"2023-09-10 21:20:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-22","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5683,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.01983,"AVALU":"mg/L","BASE2":7.81996,"BASE":8.721,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.19987,"PCHG2":2.5559,"CHG":-0.70117,"PCHG":-8.04002,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-24 03:20:32","ADY":897,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-43","SUBJID":"id-43","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":5.08774,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-08","TRTSDTM":"2020-09-10 03:20:32","TRTEDTM":"2023-09-10 21:20:32","TRT01SDTM":"2020-09-10 03:20:32","TRT01EDTM":"2022-09-10 15:20:32","TRT02SDTM":"2022-09-10 15:20:32","TRT02EDTM":"2023-09-10 21:20:32","AP01SDTM":"2020-09-10 03:20:32","AP01EDTM":"2022-09-10 15:20:32","AP02SDTM":"2022-09-10 15:20:32","AP02EDTM":"2023-09-10 21:20:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-22","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6763,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.43425,"AVALU":"mg/L","BASE2":7.81996,"BASE":8.721,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.61429,"PCHG2":7.85547,"CHG":-0.28675,"PCHG":-3.28799,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-16 03:20:32","ADY":1039,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-43","SUBJID":"id-43","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":5.08774,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-08","TRTSDTM":"2020-09-10 03:20:32","TRTEDTM":"2023-09-10 21:20:32","TRT01SDTM":"2020-09-10 03:20:32","TRT01EDTM":"2022-09-10 15:20:32","TRT02SDTM":"2022-09-10 15:20:32","TRT02EDTM":"2023-09-10 21:20:32","AP01SDTM":"2020-09-10 03:20:32","AP01EDTM":"2022-09-10 15:20:32","AP02SDTM":"2022-09-10 15:20:32","AP02EDTM":"2023-09-10 21:20:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-22","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4912,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96429,"AVALU":"g/L","BASE2":2.96429,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-24 03:20:32","ADY":195,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-43","SUBJID":"id-43","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":5.08774,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-08","TRTSDTM":"2020-09-10 03:20:32","TRTEDTM":"2023-09-10 21:20:32","TRT01SDTM":"2020-09-10 03:20:32","TRT01EDTM":"2022-09-10 15:20:32","TRT02SDTM":"2022-09-10 15:20:32","TRT02EDTM":"2023-09-10 21:20:32","AP01SDTM":"2020-09-10 03:20:32","AP01EDTM":"2022-09-10 15:20:32","AP02SDTM":"2022-09-10 15:20:32","AP02EDTM":"2023-09-10 21:20:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-22","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1567,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75858,"AVALU":"g/L","BASE2":2.96429,"BASE":2.75858,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.20571,"PCHG2":-6.93966,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-13 03:20:32","ADY":306,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-43","SUBJID":"id-43","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":5.08774,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-08","TRTSDTM":"2020-09-10 03:20:32","TRTEDTM":"2023-09-10 21:20:32","TRT01SDTM":"2020-09-10 03:20:32","TRT01EDTM":"2022-09-10 15:20:32","TRT02SDTM":"2022-09-10 15:20:32","TRT02EDTM":"2023-09-10 21:20:32","AP01SDTM":"2020-09-10 03:20:32","AP01EDTM":"2022-09-10 15:20:32","AP02SDTM":"2022-09-10 15:20:32","AP02EDTM":"2023-09-10 21:20:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-22","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6552,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92849,"AVALU":"g/L","BASE2":2.96429,"BASE":2.75858,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03579,"PCHG2":-1.20752,"CHG":0.16992,"PCHG":6.15959,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-16 03:20:32","ADY":524,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-43","SUBJID":"id-43","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":5.08774,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-08","TRTSDTM":"2020-09-10 03:20:32","TRTEDTM":"2023-09-10 21:20:32","TRT01SDTM":"2020-09-10 03:20:32","TRT01EDTM":"2022-09-10 15:20:32","TRT02SDTM":"2022-09-10 15:20:32","TRT02EDTM":"2023-09-10 21:20:32","AP01SDTM":"2020-09-10 03:20:32","AP01EDTM":"2022-09-10 15:20:32","AP02SDTM":"2022-09-10 15:20:32","AP02EDTM":"2023-09-10 21:20:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-22","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":936,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.70781,"AVALU":"g/L","BASE2":2.96429,"BASE":2.75858,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.25648,"PCHG2":-8.65236,"CHG":-0.05077,"PCHG":-1.84042,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-10 03:20:32","ADY":668,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-43","SUBJID":"id-43","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":5.08774,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-08","TRTSDTM":"2020-09-10 03:20:32","TRTEDTM":"2023-09-10 21:20:32","TRT01SDTM":"2020-09-10 03:20:32","TRT01EDTM":"2022-09-10 15:20:32","TRT02SDTM":"2022-09-10 15:20:32","TRT02EDTM":"2023-09-10 21:20:32","AP01SDTM":"2020-09-10 03:20:32","AP01EDTM":"2022-09-10 15:20:32","AP02SDTM":"2022-09-10 15:20:32","AP02EDTM":"2023-09-10 21:20:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-22","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6995,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74536,"AVALU":"g/L","BASE2":2.96429,"BASE":2.75858,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21893,"PCHG2":-7.3857,"CHG":-0.01322,"PCHG":-0.4793,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-11 03:20:32","ADY":792,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-43","SUBJID":"id-43","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":5.08774,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-08","TRTSDTM":"2020-09-10 03:20:32","TRTEDTM":"2023-09-10 21:20:32","TRT01SDTM":"2020-09-10 03:20:32","TRT01EDTM":"2022-09-10 15:20:32","TRT02SDTM":"2022-09-10 15:20:32","TRT02EDTM":"2023-09-10 21:20:32","AP01SDTM":"2020-09-10 03:20:32","AP01EDTM":"2022-09-10 15:20:32","AP02SDTM":"2022-09-10 15:20:32","AP02EDTM":"2023-09-10 21:20:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-22","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1730,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.07791,"AVALU":"g/L","BASE2":2.96429,"BASE":2.75858,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11362,"PCHG2":3.83292,"CHG":0.31933,"PCHG":11.5759,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2023-02-24 03:20:32","ADY":897,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-43","SUBJID":"id-43","SITEID":"NGA-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":5.08774,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-09-08","TRTSDTM":"2020-09-10 03:20:32","TRTEDTM":"2023-09-10 21:20:32","TRT01SDTM":"2020-09-10 03:20:32","TRT01EDTM":"2022-09-10 15:20:32","TRT02SDTM":"2022-09-10 15:20:32","TRT02EDTM":"2023-09-10 21:20:32","AP01SDTM":"2020-09-10 03:20:32","AP01EDTM":"2022-09-10 15:20:32","AP02SDTM":"2022-09-10 15:20:32","AP02EDTM":"2023-09-10 21:20:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-10","EOSDY":1096,"LSTALVDT":"2023-09-22","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1824,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92282,"AVALU":"g/L","BASE2":2.96429,"BASE":2.75858,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04147,"PCHG2":-1.39897,"CHG":0.16424,"PCHG":5.95386,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-16 03:20:32","ADY":1039,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-46","SUBJID":"id-46","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84648,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-29","TRTSDTM":"2020-04-01 20:05:10","TRTEDTM":"2022-02-18 21:52:40","TRT01SDTM":"2020-04-01 20:05:10","TRT01EDTM":"2021-02-18 15:52:40","TRT02SDTM":"2021-02-18 15:52:40","TRT02EDTM":"2022-02-18 21:52:40","AP01SDTM":"2020-04-01 20:05:10","AP01EDTM":"2021-02-18 15:52:40","AP02SDTM":"2021-02-18 15:52:40","AP02EDTM":"2022-02-18 21:52:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-28","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-28","DTHADY":697,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1373,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.70508,"AVALU":"U/L","BASE2":23.70508,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-20 20:05:10","ADY":202,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-46","SUBJID":"id-46","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84648,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-29","TRTSDTM":"2020-04-01 20:05:10","TRTEDTM":"2022-02-18 21:52:40","TRT01SDTM":"2020-04-01 20:05:10","TRT01EDTM":"2021-02-18 15:52:40","TRT02SDTM":"2021-02-18 15:52:40","TRT02EDTM":"2022-02-18 21:52:40","AP01SDTM":"2020-04-01 20:05:10","AP01EDTM":"2021-02-18 15:52:40","AP02SDTM":"2021-02-18 15:52:40","AP02EDTM":"2022-02-18 21:52:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-28","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-28","DTHADY":697,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5933,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.63995,"AVALU":"U/L","BASE2":23.70508,"BASE":27.63995,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":3.93487,"PCHG2":16.59928,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-27 20:05:10","ADY":240,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-46","SUBJID":"id-46","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84648,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-29","TRTSDTM":"2020-04-01 20:05:10","TRTEDTM":"2022-02-18 21:52:40","TRT01SDTM":"2020-04-01 20:05:10","TRT01EDTM":"2021-02-18 15:52:40","TRT02SDTM":"2021-02-18 15:52:40","TRT02EDTM":"2022-02-18 21:52:40","AP01SDTM":"2020-04-01 20:05:10","AP01EDTM":"2021-02-18 15:52:40","AP02SDTM":"2021-02-18 15:52:40","AP02EDTM":"2022-02-18 21:52:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-28","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-28","DTHADY":697,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":241,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.52433,"AVALU":"U/L","BASE2":23.70508,"BASE":27.63995,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.18074,"PCHG2":-51.38454,"CHG":-16.11562,"PCHG":-58.30552,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-06 20:05:10","ADY":311,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-46","SUBJID":"id-46","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84648,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-29","TRTSDTM":"2020-04-01 20:05:10","TRTEDTM":"2022-02-18 21:52:40","TRT01SDTM":"2020-04-01 20:05:10","TRT01EDTM":"2021-02-18 15:52:40","TRT02SDTM":"2021-02-18 15:52:40","TRT02EDTM":"2022-02-18 21:52:40","AP01SDTM":"2020-04-01 20:05:10","AP01EDTM":"2021-02-18 15:52:40","AP02SDTM":"2021-02-18 15:52:40","AP02EDTM":"2022-02-18 21:52:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-28","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-28","DTHADY":697,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7588,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.61201,"AVALU":"U/L","BASE2":23.70508,"BASE":27.63995,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.09307,"PCHG2":-21.48513,"CHG":-9.02794,"PCHG":-32.66265,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-26 20:05:10","ADY":390,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-46","SUBJID":"id-46","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84648,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-29","TRTSDTM":"2020-04-01 20:05:10","TRTEDTM":"2022-02-18 21:52:40","TRT01SDTM":"2020-04-01 20:05:10","TRT01EDTM":"2021-02-18 15:52:40","TRT02SDTM":"2021-02-18 15:52:40","TRT02EDTM":"2022-02-18 21:52:40","AP01SDTM":"2020-04-01 20:05:10","AP01EDTM":"2021-02-18 15:52:40","AP02SDTM":"2021-02-18 15:52:40","AP02EDTM":"2022-02-18 21:52:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-28","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-28","DTHADY":697,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1966,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.27819,"AVALU":"U/L","BASE2":23.70508,"BASE":27.63995,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.42689,"PCHG2":-39.76739,"CHG":-13.36176,"PCHG":-48.34221,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-09 20:05:10","ADY":526,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-46","SUBJID":"id-46","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84648,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-29","TRTSDTM":"2020-04-01 20:05:10","TRTEDTM":"2022-02-18 21:52:40","TRT01SDTM":"2020-04-01 20:05:10","TRT01EDTM":"2021-02-18 15:52:40","TRT02SDTM":"2021-02-18 15:52:40","TRT02EDTM":"2022-02-18 21:52:40","AP01SDTM":"2020-04-01 20:05:10","AP01EDTM":"2021-02-18 15:52:40","AP02SDTM":"2021-02-18 15:52:40","AP02EDTM":"2022-02-18 21:52:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-28","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-28","DTHADY":697,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1205,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.74192,"AVALU":"U/L","BASE2":23.70508,"BASE":27.63995,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.03684,"PCHG2":17.02944,"CHG":0.10197,"PCHG":0.36893,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-25 20:05:10","ADY":603,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-46","SUBJID":"id-46","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84648,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-29","TRTSDTM":"2020-04-01 20:05:10","TRTEDTM":"2022-02-18 21:52:40","TRT01SDTM":"2020-04-01 20:05:10","TRT01EDTM":"2021-02-18 15:52:40","TRT02SDTM":"2021-02-18 15:52:40","TRT02EDTM":"2022-02-18 21:52:40","AP01SDTM":"2020-04-01 20:05:10","AP01EDTM":"2021-02-18 15:52:40","AP02SDTM":"2021-02-18 15:52:40","AP02EDTM":"2022-02-18 21:52:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-28","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-28","DTHADY":697,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6275,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.11772,"AVALU":"U/L","BASE2":23.70508,"BASE":27.63995,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.58735,"PCHG2":-2.47775,"CHG":-4.52222,"PCHG":-16.36119,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-31 20:05:10","ADY":670,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-46","SUBJID":"id-46","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84648,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-29","TRTSDTM":"2020-04-01 20:05:10","TRTEDTM":"2022-02-18 21:52:40","TRT01SDTM":"2020-04-01 20:05:10","TRT01EDTM":"2021-02-18 15:52:40","TRT02SDTM":"2021-02-18 15:52:40","TRT02EDTM":"2022-02-18 21:52:40","AP01SDTM":"2020-04-01 20:05:10","AP01EDTM":"2021-02-18 15:52:40","AP02SDTM":"2021-02-18 15:52:40","AP02EDTM":"2022-02-18 21:52:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-28","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-28","DTHADY":697,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":958,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.34741,"AVALU":"mg/L","BASE2":8.34741,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-20 20:05:10","ADY":202,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-46","SUBJID":"id-46","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84648,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-29","TRTSDTM":"2020-04-01 20:05:10","TRTEDTM":"2022-02-18 21:52:40","TRT01SDTM":"2020-04-01 20:05:10","TRT01EDTM":"2021-02-18 15:52:40","TRT02SDTM":"2021-02-18 15:52:40","TRT02EDTM":"2022-02-18 21:52:40","AP01SDTM":"2020-04-01 20:05:10","AP01EDTM":"2021-02-18 15:52:40","AP02SDTM":"2021-02-18 15:52:40","AP02EDTM":"2022-02-18 21:52:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-28","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-28","DTHADY":697,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3873,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.45917,"AVALU":"mg/L","BASE2":8.34741,"BASE":9.45917,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.11176,"PCHG2":13.31861,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-27 20:05:10","ADY":240,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-46","SUBJID":"id-46","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84648,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-29","TRTSDTM":"2020-04-01 20:05:10","TRTEDTM":"2022-02-18 21:52:40","TRT01SDTM":"2020-04-01 20:05:10","TRT01EDTM":"2021-02-18 15:52:40","TRT02SDTM":"2021-02-18 15:52:40","TRT02EDTM":"2022-02-18 21:52:40","AP01SDTM":"2020-04-01 20:05:10","AP01EDTM":"2021-02-18 15:52:40","AP02SDTM":"2021-02-18 15:52:40","AP02EDTM":"2022-02-18 21:52:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-28","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-28","DTHADY":697,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5437,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.20861,"AVALU":"mg/L","BASE2":8.34741,"BASE":9.45917,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.8612,"PCHG2":22.29677,"CHG":0.74944,"PCHG":7.92294,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-02-06 20:05:10","ADY":311,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-46","SUBJID":"id-46","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84648,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-29","TRTSDTM":"2020-04-01 20:05:10","TRTEDTM":"2022-02-18 21:52:40","TRT01SDTM":"2020-04-01 20:05:10","TRT01EDTM":"2021-02-18 15:52:40","TRT02SDTM":"2021-02-18 15:52:40","TRT02EDTM":"2022-02-18 21:52:40","AP01SDTM":"2020-04-01 20:05:10","AP01EDTM":"2021-02-18 15:52:40","AP02SDTM":"2021-02-18 15:52:40","AP02EDTM":"2022-02-18 21:52:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-28","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-28","DTHADY":697,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2128,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.38348,"AVALU":"mg/L","BASE2":8.34741,"BASE":9.45917,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.96393,"PCHG2":-11.54766,"CHG":-2.07569,"PCHG":-21.94368,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-04-26 20:05:10","ADY":390,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-46","SUBJID":"id-46","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84648,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-29","TRTSDTM":"2020-04-01 20:05:10","TRTEDTM":"2022-02-18 21:52:40","TRT01SDTM":"2020-04-01 20:05:10","TRT01EDTM":"2021-02-18 15:52:40","TRT02SDTM":"2021-02-18 15:52:40","TRT02EDTM":"2022-02-18 21:52:40","AP01SDTM":"2020-04-01 20:05:10","AP01EDTM":"2021-02-18 15:52:40","AP02SDTM":"2021-02-18 15:52:40","AP02EDTM":"2022-02-18 21:52:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-28","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-28","DTHADY":697,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5715,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.66093,"AVALU":"mg/L","BASE2":8.34741,"BASE":9.45917,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.31353,"PCHG2":15.73574,"CHG":0.20177,"PCHG":2.13304,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-09 20:05:10","ADY":526,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-46","SUBJID":"id-46","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84648,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-29","TRTSDTM":"2020-04-01 20:05:10","TRTEDTM":"2022-02-18 21:52:40","TRT01SDTM":"2020-04-01 20:05:10","TRT01EDTM":"2021-02-18 15:52:40","TRT02SDTM":"2021-02-18 15:52:40","TRT02EDTM":"2022-02-18 21:52:40","AP01SDTM":"2020-04-01 20:05:10","AP01EDTM":"2021-02-18 15:52:40","AP02SDTM":"2021-02-18 15:52:40","AP02EDTM":"2022-02-18 21:52:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-28","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-28","DTHADY":697,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7553,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.93213,"AVALU":"mg/L","BASE2":8.34741,"BASE":9.45917,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.58472,"PCHG2":18.9846,"CHG":0.47296,"PCHG":5.00005,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-25 20:05:10","ADY":603,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-46","SUBJID":"id-46","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84648,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-29","TRTSDTM":"2020-04-01 20:05:10","TRTEDTM":"2022-02-18 21:52:40","TRT01SDTM":"2020-04-01 20:05:10","TRT01EDTM":"2021-02-18 15:52:40","TRT02SDTM":"2021-02-18 15:52:40","TRT02EDTM":"2022-02-18 21:52:40","AP01SDTM":"2020-04-01 20:05:10","AP01EDTM":"2021-02-18 15:52:40","AP02SDTM":"2021-02-18 15:52:40","AP02EDTM":"2022-02-18 21:52:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-28","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-28","DTHADY":697,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3038,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.35826,"AVALU":"mg/L","BASE2":8.34741,"BASE":9.45917,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01086,"PCHG2":0.13006,"CHG":-1.1009,"PCHG":-11.63846,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-31 20:05:10","ADY":670,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-46","SUBJID":"id-46","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84648,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-29","TRTSDTM":"2020-04-01 20:05:10","TRTEDTM":"2022-02-18 21:52:40","TRT01SDTM":"2020-04-01 20:05:10","TRT01EDTM":"2021-02-18 15:52:40","TRT02SDTM":"2021-02-18 15:52:40","TRT02EDTM":"2022-02-18 21:52:40","AP01SDTM":"2020-04-01 20:05:10","AP01EDTM":"2021-02-18 15:52:40","AP02SDTM":"2021-02-18 15:52:40","AP02EDTM":"2022-02-18 21:52:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-28","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-28","DTHADY":697,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8230,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00889,"AVALU":"g/L","BASE2":3.00889,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-10-20 20:05:10","ADY":202,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-46","SUBJID":"id-46","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84648,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-29","TRTSDTM":"2020-04-01 20:05:10","TRTEDTM":"2022-02-18 21:52:40","TRT01SDTM":"2020-04-01 20:05:10","TRT01EDTM":"2021-02-18 15:52:40","TRT02SDTM":"2021-02-18 15:52:40","TRT02EDTM":"2022-02-18 21:52:40","AP01SDTM":"2020-04-01 20:05:10","AP01EDTM":"2021-02-18 15:52:40","AP02SDTM":"2021-02-18 15:52:40","AP02EDTM":"2022-02-18 21:52:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-28","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-28","DTHADY":697,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1180,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74564,"AVALU":"g/L","BASE2":3.00889,"BASE":2.74564,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.26325,"PCHG2":-8.74904,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-27 20:05:10","ADY":240,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-46","SUBJID":"id-46","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84648,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-29","TRTSDTM":"2020-04-01 20:05:10","TRTEDTM":"2022-02-18 21:52:40","TRT01SDTM":"2020-04-01 20:05:10","TRT01EDTM":"2021-02-18 15:52:40","TRT02SDTM":"2021-02-18 15:52:40","TRT02EDTM":"2022-02-18 21:52:40","AP01SDTM":"2020-04-01 20:05:10","AP01EDTM":"2021-02-18 15:52:40","AP02SDTM":"2021-02-18 15:52:40","AP02EDTM":"2022-02-18 21:52:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-28","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-28","DTHADY":697,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3728,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92372,"AVALU":"g/L","BASE2":3.00889,"BASE":2.74564,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08517,"PCHG2":-2.83057,"CHG":0.17808,"PCHG":6.48593,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-06 20:05:10","ADY":311,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-46","SUBJID":"id-46","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84648,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-29","TRTSDTM":"2020-04-01 20:05:10","TRTEDTM":"2022-02-18 21:52:40","TRT01SDTM":"2020-04-01 20:05:10","TRT01EDTM":"2021-02-18 15:52:40","TRT02SDTM":"2021-02-18 15:52:40","TRT02EDTM":"2022-02-18 21:52:40","AP01SDTM":"2020-04-01 20:05:10","AP01EDTM":"2021-02-18 15:52:40","AP02SDTM":"2021-02-18 15:52:40","AP02EDTM":"2022-02-18 21:52:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-28","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-28","DTHADY":697,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6397,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.995,"AVALU":"g/L","BASE2":3.00889,"BASE":2.74564,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0139,"PCHG2":-0.46182,"CHG":0.24935,"PCHG":9.08179,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-26 20:05:10","ADY":390,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-46","SUBJID":"id-46","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84648,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-29","TRTSDTM":"2020-04-01 20:05:10","TRTEDTM":"2022-02-18 21:52:40","TRT01SDTM":"2020-04-01 20:05:10","TRT01EDTM":"2021-02-18 15:52:40","TRT02SDTM":"2021-02-18 15:52:40","TRT02EDTM":"2022-02-18 21:52:40","AP01SDTM":"2020-04-01 20:05:10","AP01EDTM":"2021-02-18 15:52:40","AP02SDTM":"2021-02-18 15:52:40","AP02EDTM":"2022-02-18 21:52:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-28","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-28","DTHADY":697,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7184,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02713,"AVALU":"g/L","BASE2":3.00889,"BASE":2.74564,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01824,"PCHG2":0.60614,"CHG":0.28149,"PCHG":10.25215,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-09-09 20:05:10","ADY":526,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-46","SUBJID":"id-46","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84648,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-29","TRTSDTM":"2020-04-01 20:05:10","TRTEDTM":"2022-02-18 21:52:40","TRT01SDTM":"2020-04-01 20:05:10","TRT01EDTM":"2021-02-18 15:52:40","TRT02SDTM":"2021-02-18 15:52:40","TRT02EDTM":"2022-02-18 21:52:40","AP01SDTM":"2020-04-01 20:05:10","AP01EDTM":"2021-02-18 15:52:40","AP02SDTM":"2021-02-18 15:52:40","AP02EDTM":"2022-02-18 21:52:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-28","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-28","DTHADY":697,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5726,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77323,"AVALU":"g/L","BASE2":3.00889,"BASE":2.74564,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.23566,"PCHG2":-7.83211,"CHG":0.02759,"PCHG":1.00485,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-25 20:05:10","ADY":603,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-46","SUBJID":"id-46","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":3.84648,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-29","TRTSDTM":"2020-04-01 20:05:10","TRTEDTM":"2022-02-18 21:52:40","TRT01SDTM":"2020-04-01 20:05:10","TRT01EDTM":"2021-02-18 15:52:40","TRT02SDTM":"2021-02-18 15:52:40","TRT02EDTM":"2022-02-18 21:52:40","AP01SDTM":"2020-04-01 20:05:10","AP01EDTM":"2021-02-18 15:52:40","AP02SDTM":"2021-02-18 15:52:40","AP02EDTM":"2022-02-18 21:52:40","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-28","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":10,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-28","DTHADY":697,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4147,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98483,"AVALU":"g/L","BASE2":3.00889,"BASE":2.74564,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02407,"PCHG2":-0.79981,"CHG":0.23918,"PCHG":8.7114,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-31 20:05:10","ADY":670,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-96","SUBJID":"id-96","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":12.92348,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-21 22:20:59","TRTEDTM":"2022-02-16 07:42:06","TRT01SDTM":"2019-07-21 22:20:59","TRT01EDTM":"2021-02-16 01:42:06","TRT02SDTM":"2021-02-16 01:42:06","TRT02EDTM":"2022-02-16 07:42:06","AP01SDTM":"2019-07-21 22:20:59","AP01EDTM":"2021-02-16 01:42:06","AP02SDTM":"2021-02-16 01:42:06","AP02EDTM":"2022-02-16 07:42:06","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":941,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-02-28","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5977,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.90054,"AVALU":"U/L","BASE2":10.90054,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-12 22:20:59","ADY":53,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-96","SUBJID":"id-96","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":12.92348,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-21 22:20:59","TRTEDTM":"2022-02-16 07:42:06","TRT01SDTM":"2019-07-21 22:20:59","TRT01EDTM":"2021-02-16 01:42:06","TRT02SDTM":"2021-02-16 01:42:06","TRT02EDTM":"2022-02-16 07:42:06","AP01SDTM":"2019-07-21 22:20:59","AP01EDTM":"2021-02-16 01:42:06","AP02SDTM":"2021-02-16 01:42:06","AP02EDTM":"2022-02-16 07:42:06","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":941,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-02-28","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6113,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.96846,"AVALU":"U/L","BASE2":10.90054,"BASE":24.96846,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":14.06792,"PCHG2":129.05717,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-03 22:20:59","ADY":166,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-96","SUBJID":"id-96","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":12.92348,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-21 22:20:59","TRTEDTM":"2022-02-16 07:42:06","TRT01SDTM":"2019-07-21 22:20:59","TRT01EDTM":"2021-02-16 01:42:06","TRT02SDTM":"2021-02-16 01:42:06","TRT02EDTM":"2022-02-16 07:42:06","AP01SDTM":"2019-07-21 22:20:59","AP01EDTM":"2021-02-16 01:42:06","AP02SDTM":"2021-02-16 01:42:06","AP02EDTM":"2022-02-16 07:42:06","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":941,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-02-28","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3135,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.03856,"AVALU":"U/L","BASE2":10.90054,"BASE":24.96846,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.86197,"PCHG2":-7.90761,"CHG":-14.92989,"PCHG":-59.79502,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-12 22:20:59","ADY":327,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-96","SUBJID":"id-96","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":12.92348,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-21 22:20:59","TRTEDTM":"2022-02-16 07:42:06","TRT01SDTM":"2019-07-21 22:20:59","TRT01EDTM":"2021-02-16 01:42:06","TRT02SDTM":"2021-02-16 01:42:06","TRT02EDTM":"2022-02-16 07:42:06","AP01SDTM":"2019-07-21 22:20:59","AP01EDTM":"2021-02-16 01:42:06","AP02SDTM":"2021-02-16 01:42:06","AP02EDTM":"2022-02-16 07:42:06","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":941,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-02-28","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7097,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.12304,"AVALU":"U/L","BASE2":10.90054,"BASE":24.96846,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.22251,"PCHG2":75.43213,"CHG":-5.84542,"PCHG":-23.4112,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-25 22:20:59","ADY":493,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-96","SUBJID":"id-96","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":12.92348,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-21 22:20:59","TRTEDTM":"2022-02-16 07:42:06","TRT01SDTM":"2019-07-21 22:20:59","TRT01EDTM":"2021-02-16 01:42:06","TRT02SDTM":"2021-02-16 01:42:06","TRT02EDTM":"2022-02-16 07:42:06","AP01SDTM":"2019-07-21 22:20:59","AP01EDTM":"2021-02-16 01:42:06","AP02SDTM":"2021-02-16 01:42:06","AP02EDTM":"2022-02-16 07:42:06","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":941,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-02-28","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2005,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.53554,"AVALU":"U/L","BASE2":10.90054,"BASE":24.96846,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":17.63501,"PCHG2":161.78111,"CHG":3.56708,"PCHG":14.28636,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-03 22:20:59","ADY":563,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-96","SUBJID":"id-96","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":12.92348,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-21 22:20:59","TRTEDTM":"2022-02-16 07:42:06","TRT01SDTM":"2019-07-21 22:20:59","TRT01EDTM":"2021-02-16 01:42:06","TRT02SDTM":"2021-02-16 01:42:06","TRT02EDTM":"2022-02-16 07:42:06","AP01SDTM":"2019-07-21 22:20:59","AP01EDTM":"2021-02-16 01:42:06","AP02SDTM":"2021-02-16 01:42:06","AP02EDTM":"2022-02-16 07:42:06","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":941,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-02-28","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":211,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.44605,"AVALU":"U/L","BASE2":10.90054,"BASE":24.96846,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.54551,"PCHG2":87.56919,"CHG":-4.52241,"PCHG":-18.1125,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-13 22:20:59","ADY":907,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-96","SUBJID":"id-96","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":12.92348,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-21 22:20:59","TRTEDTM":"2022-02-16 07:42:06","TRT01SDTM":"2019-07-21 22:20:59","TRT01EDTM":"2021-02-16 01:42:06","TRT02SDTM":"2021-02-16 01:42:06","TRT02EDTM":"2022-02-16 07:42:06","AP01SDTM":"2019-07-21 22:20:59","AP01EDTM":"2021-02-16 01:42:06","AP02SDTM":"2021-02-16 01:42:06","AP02EDTM":"2022-02-16 07:42:06","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":941,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-02-28","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7993,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.94276,"AVALU":"U/L","BASE2":10.90054,"BASE":24.96846,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":22.04222,"PCHG2":202.21228,"CHG":7.9743,"PCHG":31.93749,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-26 22:20:59","ADY":920,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-96","SUBJID":"id-96","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":12.92348,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-21 22:20:59","TRTEDTM":"2022-02-16 07:42:06","TRT01SDTM":"2019-07-21 22:20:59","TRT01EDTM":"2021-02-16 01:42:06","TRT02SDTM":"2021-02-16 01:42:06","TRT02EDTM":"2022-02-16 07:42:06","AP01SDTM":"2019-07-21 22:20:59","AP01EDTM":"2021-02-16 01:42:06","AP02SDTM":"2021-02-16 01:42:06","AP02EDTM":"2022-02-16 07:42:06","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":941,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-02-28","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1376,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.74722,"AVALU":"mg/L","BASE2":9.74722,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-12 22:20:59","ADY":53,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-96","SUBJID":"id-96","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":12.92348,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-21 22:20:59","TRTEDTM":"2022-02-16 07:42:06","TRT01SDTM":"2019-07-21 22:20:59","TRT01EDTM":"2021-02-16 01:42:06","TRT02SDTM":"2021-02-16 01:42:06","TRT02EDTM":"2022-02-16 07:42:06","AP01SDTM":"2019-07-21 22:20:59","AP01EDTM":"2021-02-16 01:42:06","AP02SDTM":"2021-02-16 01:42:06","AP02EDTM":"2022-02-16 07:42:06","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":941,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-02-28","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4316,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.05236,"AVALU":"mg/L","BASE2":9.74722,"BASE":9.05236,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.69486,"PCHG2":-7.12877,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-03 22:20:59","ADY":166,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-96","SUBJID":"id-96","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":12.92348,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-21 22:20:59","TRTEDTM":"2022-02-16 07:42:06","TRT01SDTM":"2019-07-21 22:20:59","TRT01EDTM":"2021-02-16 01:42:06","TRT02SDTM":"2021-02-16 01:42:06","TRT02EDTM":"2022-02-16 07:42:06","AP01SDTM":"2019-07-21 22:20:59","AP01EDTM":"2021-02-16 01:42:06","AP02SDTM":"2021-02-16 01:42:06","AP02EDTM":"2022-02-16 07:42:06","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":941,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-02-28","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1094,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.12752,"AVALU":"mg/L","BASE2":9.74722,"BASE":9.05236,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.6197,"PCHG2":-6.35768,"CHG":0.07516,"PCHG":0.83028,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-12 22:20:59","ADY":327,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-96","SUBJID":"id-96","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":12.92348,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-21 22:20:59","TRTEDTM":"2022-02-16 07:42:06","TRT01SDTM":"2019-07-21 22:20:59","TRT01EDTM":"2021-02-16 01:42:06","TRT02SDTM":"2021-02-16 01:42:06","TRT02EDTM":"2022-02-16 07:42:06","AP01SDTM":"2019-07-21 22:20:59","AP01EDTM":"2021-02-16 01:42:06","AP02SDTM":"2021-02-16 01:42:06","AP02EDTM":"2022-02-16 07:42:06","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":941,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-02-28","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1602,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.66686,"AVALU":"mg/L","BASE2":9.74722,"BASE":9.05236,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08035,"PCHG2":-0.82438,"CHG":0.6145,"PCHG":6.78831,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-25 22:20:59","ADY":493,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-96","SUBJID":"id-96","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":12.92348,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-21 22:20:59","TRTEDTM":"2022-02-16 07:42:06","TRT01SDTM":"2019-07-21 22:20:59","TRT01EDTM":"2021-02-16 01:42:06","TRT02SDTM":"2021-02-16 01:42:06","TRT02EDTM":"2022-02-16 07:42:06","AP01SDTM":"2019-07-21 22:20:59","AP01EDTM":"2021-02-16 01:42:06","AP02SDTM":"2021-02-16 01:42:06","AP02EDTM":"2022-02-16 07:42:06","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":941,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-02-28","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6811,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.78826,"AVALU":"mg/L","BASE2":9.74722,"BASE":9.05236,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.95896,"PCHG2":-20.09759,"CHG":-1.2641,"PCHG":-13.96431,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-02-03 22:20:59","ADY":563,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-96","SUBJID":"id-96","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":12.92348,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-21 22:20:59","TRTEDTM":"2022-02-16 07:42:06","TRT01SDTM":"2019-07-21 22:20:59","TRT01EDTM":"2021-02-16 01:42:06","TRT02SDTM":"2021-02-16 01:42:06","TRT02EDTM":"2022-02-16 07:42:06","AP01SDTM":"2019-07-21 22:20:59","AP01EDTM":"2021-02-16 01:42:06","AP02SDTM":"2021-02-16 01:42:06","AP02EDTM":"2022-02-16 07:42:06","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":941,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-02-28","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4918,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.75042,"AVALU":"mg/L","BASE2":9.74722,"BASE":9.05236,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.99679,"PCHG2":-20.48576,"CHG":-1.30194,"PCHG":-14.38228,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-01-13 22:20:59","ADY":907,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-96","SUBJID":"id-96","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":12.92348,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-21 22:20:59","TRTEDTM":"2022-02-16 07:42:06","TRT01SDTM":"2019-07-21 22:20:59","TRT01EDTM":"2021-02-16 01:42:06","TRT02SDTM":"2021-02-16 01:42:06","TRT02EDTM":"2022-02-16 07:42:06","AP01SDTM":"2019-07-21 22:20:59","AP01EDTM":"2021-02-16 01:42:06","AP02SDTM":"2021-02-16 01:42:06","AP02EDTM":"2022-02-16 07:42:06","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":941,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-02-28","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8360,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.39321,"AVALU":"mg/L","BASE2":9.74722,"BASE":9.05236,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.35401,"PCHG2":-13.89124,"CHG":-0.65915,"PCHG":-7.28156,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-26 22:20:59","ADY":920,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-96","SUBJID":"id-96","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":12.92348,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-21 22:20:59","TRTEDTM":"2022-02-16 07:42:06","TRT01SDTM":"2019-07-21 22:20:59","TRT01EDTM":"2021-02-16 01:42:06","TRT02SDTM":"2021-02-16 01:42:06","TRT02EDTM":"2022-02-16 07:42:06","AP01SDTM":"2019-07-21 22:20:59","AP01EDTM":"2021-02-16 01:42:06","AP02SDTM":"2021-02-16 01:42:06","AP02EDTM":"2022-02-16 07:42:06","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":941,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-02-28","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6032,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74456,"AVALU":"g/L","BASE2":2.74456,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-12 22:20:59","ADY":53,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-96","SUBJID":"id-96","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":12.92348,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-21 22:20:59","TRTEDTM":"2022-02-16 07:42:06","TRT01SDTM":"2019-07-21 22:20:59","TRT01EDTM":"2021-02-16 01:42:06","TRT02SDTM":"2021-02-16 01:42:06","TRT02EDTM":"2022-02-16 07:42:06","AP01SDTM":"2019-07-21 22:20:59","AP01EDTM":"2021-02-16 01:42:06","AP02SDTM":"2021-02-16 01:42:06","AP02EDTM":"2022-02-16 07:42:06","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":941,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-02-28","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7461,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82903,"AVALU":"g/L","BASE2":2.74456,"BASE":2.82903,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.08446,"PCHG2":3.0775,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-03 22:20:59","ADY":166,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-96","SUBJID":"id-96","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":12.92348,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-21 22:20:59","TRTEDTM":"2022-02-16 07:42:06","TRT01SDTM":"2019-07-21 22:20:59","TRT01EDTM":"2021-02-16 01:42:06","TRT02SDTM":"2021-02-16 01:42:06","TRT02EDTM":"2022-02-16 07:42:06","AP01SDTM":"2019-07-21 22:20:59","AP01EDTM":"2021-02-16 01:42:06","AP02SDTM":"2021-02-16 01:42:06","AP02EDTM":"2022-02-16 07:42:06","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":941,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-02-28","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7501,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05795,"AVALU":"g/L","BASE2":2.74456,"BASE":2.82903,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.31339,"PCHG2":11.41852,"CHG":0.22892,"PCHG":8.092,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-06-12 22:20:59","ADY":327,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-96","SUBJID":"id-96","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":12.92348,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-21 22:20:59","TRTEDTM":"2022-02-16 07:42:06","TRT01SDTM":"2019-07-21 22:20:59","TRT01EDTM":"2021-02-16 01:42:06","TRT02SDTM":"2021-02-16 01:42:06","TRT02EDTM":"2022-02-16 07:42:06","AP01SDTM":"2019-07-21 22:20:59","AP01EDTM":"2021-02-16 01:42:06","AP02SDTM":"2021-02-16 01:42:06","AP02EDTM":"2022-02-16 07:42:06","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":941,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-02-28","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4954,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75455,"AVALU":"g/L","BASE2":2.74456,"BASE":2.82903,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00999,"PCHG2":0.36387,"CHG":-0.07448,"PCHG":-2.6326,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-25 22:20:59","ADY":493,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-96","SUBJID":"id-96","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":12.92348,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-21 22:20:59","TRTEDTM":"2022-02-16 07:42:06","TRT01SDTM":"2019-07-21 22:20:59","TRT01EDTM":"2021-02-16 01:42:06","TRT02SDTM":"2021-02-16 01:42:06","TRT02EDTM":"2022-02-16 07:42:06","AP01SDTM":"2019-07-21 22:20:59","AP01EDTM":"2021-02-16 01:42:06","AP02SDTM":"2021-02-16 01:42:06","AP02EDTM":"2022-02-16 07:42:06","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":941,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-02-28","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4287,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03712,"AVALU":"g/L","BASE2":2.74456,"BASE":2.82903,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.29256,"PCHG2":10.65949,"CHG":0.20809,"PCHG":7.35562,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-02-03 22:20:59","ADY":563,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-96","SUBJID":"id-96","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":12.92348,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-21 22:20:59","TRTEDTM":"2022-02-16 07:42:06","TRT01SDTM":"2019-07-21 22:20:59","TRT01EDTM":"2021-02-16 01:42:06","TRT02SDTM":"2021-02-16 01:42:06","TRT02EDTM":"2022-02-16 07:42:06","AP01SDTM":"2019-07-21 22:20:59","AP01EDTM":"2021-02-16 01:42:06","AP02SDTM":"2021-02-16 01:42:06","AP02EDTM":"2022-02-16 07:42:06","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":941,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-02-28","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1150,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85503,"AVALU":"g/L","BASE2":2.74456,"BASE":2.82903,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11046,"PCHG2":4.02481,"CHG":0.026,"PCHG":0.91903,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-13 22:20:59","ADY":907,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-1-id-96","SUBJID":"id-96","SITEID":"NGA-1","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-1","INVNAM":"Dr. NGA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":12.92348,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-17","TRTSDTM":"2019-07-21 22:20:59","TRTEDTM":"2022-02-16 07:42:06","TRT01SDTM":"2019-07-21 22:20:59","TRT01EDTM":"2021-02-16 01:42:06","TRT02SDTM":"2021-02-16 01:42:06","TRT02EDTM":"2022-02-16 07:42:06","AP01SDTM":"2019-07-21 22:20:59","AP01EDTM":"2021-02-16 01:42:06","AP02SDTM":"2021-02-16 01:42:06","AP02EDTM":"2022-02-16 07:42:06","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":941,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-02-28","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6584,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89854,"AVALU":"g/L","BASE2":2.74456,"BASE":2.82903,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15398,"PCHG2":5.61043,"CHG":0.06952,"PCHG":2.45731,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-26 22:20:59","ADY":920,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-173","SUBJID":"id-173","SITEID":"NGA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.99723,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-03-08","TRTSDTM":"2019-03-10 09:35:30","TRTEDTM":"2022-03-10 03:35:30","TRT01SDTM":"2019-03-10 09:35:30","TRT01EDTM":"2021-03-09 21:35:30","TRT02SDTM":"2021-03-09 21:35:30","TRT02EDTM":"2022-03-10 03:35:30","AP01SDTM":"2019-03-10 09:35:30","AP01EDTM":"2021-03-09 21:35:30","AP02SDTM":"2021-03-09 21:35:30","AP02EDTM":"2022-03-10 03:35:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-10","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2891,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.75781,"AVALU":"U/L","BASE2":23.75781,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-30 09:35:30","ADY":295,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-173","SUBJID":"id-173","SITEID":"NGA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.99723,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-03-08","TRTSDTM":"2019-03-10 09:35:30","TRTEDTM":"2022-03-10 03:35:30","TRT01SDTM":"2019-03-10 09:35:30","TRT01EDTM":"2021-03-09 21:35:30","TRT02SDTM":"2021-03-09 21:35:30","TRT02EDTM":"2022-03-10 03:35:30","AP01SDTM":"2019-03-10 09:35:30","AP01EDTM":"2021-03-09 21:35:30","AP02SDTM":"2021-03-09 21:35:30","AP02EDTM":"2022-03-10 03:35:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-10","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2246,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.25043,"AVALU":"U/L","BASE2":23.75781,"BASE":25.25043,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.49262,"PCHG2":6.28264,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-26 09:35:30","ADY":413,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-173","SUBJID":"id-173","SITEID":"NGA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.99723,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-03-08","TRTSDTM":"2019-03-10 09:35:30","TRTEDTM":"2022-03-10 03:35:30","TRT01SDTM":"2019-03-10 09:35:30","TRT01EDTM":"2021-03-09 21:35:30","TRT02SDTM":"2021-03-09 21:35:30","TRT02EDTM":"2022-03-10 03:35:30","AP01SDTM":"2019-03-10 09:35:30","AP01EDTM":"2021-03-09 21:35:30","AP02SDTM":"2021-03-09 21:35:30","AP02EDTM":"2022-03-10 03:35:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-10","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5441,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.91874,"AVALU":"U/L","BASE2":23.75781,"BASE":25.25043,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.16093,"PCHG2":4.88651,"CHG":-0.33169,"PCHG":-1.3136,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-21 09:35:30","ADY":530,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-173","SUBJID":"id-173","SITEID":"NGA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.99723,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-03-08","TRTSDTM":"2019-03-10 09:35:30","TRTEDTM":"2022-03-10 03:35:30","TRT01SDTM":"2019-03-10 09:35:30","TRT01EDTM":"2021-03-09 21:35:30","TRT02SDTM":"2021-03-09 21:35:30","TRT02EDTM":"2022-03-10 03:35:30","AP01SDTM":"2019-03-10 09:35:30","AP01EDTM":"2021-03-09 21:35:30","AP02SDTM":"2021-03-09 21:35:30","AP02EDTM":"2022-03-10 03:35:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-10","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2579,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.01008,"AVALU":"U/L","BASE2":23.75781,"BASE":25.25043,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.25227,"PCHG2":5.27098,"CHG":-0.24035,"PCHG":-0.95186,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-24 09:35:30","ADY":686,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-173","SUBJID":"id-173","SITEID":"NGA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.99723,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-03-08","TRTSDTM":"2019-03-10 09:35:30","TRTEDTM":"2022-03-10 03:35:30","TRT01SDTM":"2019-03-10 09:35:30","TRT01EDTM":"2021-03-09 21:35:30","TRT02SDTM":"2021-03-09 21:35:30","TRT02EDTM":"2022-03-10 03:35:30","AP01SDTM":"2019-03-10 09:35:30","AP01EDTM":"2021-03-09 21:35:30","AP02SDTM":"2021-03-09 21:35:30","AP02EDTM":"2022-03-10 03:35:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-10","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":408,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.90749,"AVALU":"U/L","BASE2":23.75781,"BASE":25.25043,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.14967,"PCHG2":25.88484,"CHG":4.65705,"PCHG":18.44346,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-27 09:35:30","ADY":870,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-173","SUBJID":"id-173","SITEID":"NGA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.99723,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-03-08","TRTSDTM":"2019-03-10 09:35:30","TRTEDTM":"2022-03-10 03:35:30","TRT01SDTM":"2019-03-10 09:35:30","TRT01EDTM":"2021-03-09 21:35:30","TRT02SDTM":"2021-03-09 21:35:30","TRT02EDTM":"2022-03-10 03:35:30","AP01SDTM":"2019-03-10 09:35:30","AP01EDTM":"2021-03-09 21:35:30","AP02SDTM":"2021-03-09 21:35:30","AP02EDTM":"2022-03-10 03:35:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-10","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1414,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.5664,"AVALU":"U/L","BASE2":23.75781,"BASE":25.25043,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19142,"PCHG2":-0.8057,"CHG":-1.68403,"PCHG":-6.66933,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-07 09:35:30","ADY":881,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-173","SUBJID":"id-173","SITEID":"NGA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.99723,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-03-08","TRTSDTM":"2019-03-10 09:35:30","TRTEDTM":"2022-03-10 03:35:30","TRT01SDTM":"2019-03-10 09:35:30","TRT01EDTM":"2021-03-09 21:35:30","TRT02SDTM":"2021-03-09 21:35:30","TRT02EDTM":"2022-03-10 03:35:30","AP01SDTM":"2019-03-10 09:35:30","AP01EDTM":"2021-03-09 21:35:30","AP02SDTM":"2021-03-09 21:35:30","AP02EDTM":"2022-03-10 03:35:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-10","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":529,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.63711,"AVALU":"U/L","BASE2":23.75781,"BASE":25.25043,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.12071,"PCHG2":-29.97206,"CHG":-8.61332,"PCHG":-34.11159,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-20 09:35:30","ADY":1078,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-173","SUBJID":"id-173","SITEID":"NGA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.99723,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-03-08","TRTSDTM":"2019-03-10 09:35:30","TRTEDTM":"2022-03-10 03:35:30","TRT01SDTM":"2019-03-10 09:35:30","TRT01EDTM":"2021-03-09 21:35:30","TRT02SDTM":"2021-03-09 21:35:30","TRT02EDTM":"2022-03-10 03:35:30","AP01SDTM":"2019-03-10 09:35:30","AP01EDTM":"2021-03-09 21:35:30","AP02SDTM":"2021-03-09 21:35:30","AP02EDTM":"2022-03-10 03:35:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-10","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":654,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.22447,"AVALU":"mg/L","BASE2":9.22447,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-30 09:35:30","ADY":295,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-173","SUBJID":"id-173","SITEID":"NGA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.99723,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-03-08","TRTSDTM":"2019-03-10 09:35:30","TRTEDTM":"2022-03-10 03:35:30","TRT01SDTM":"2019-03-10 09:35:30","TRT01EDTM":"2021-03-09 21:35:30","TRT02SDTM":"2021-03-09 21:35:30","TRT02EDTM":"2022-03-10 03:35:30","AP01SDTM":"2019-03-10 09:35:30","AP01EDTM":"2021-03-09 21:35:30","AP02SDTM":"2021-03-09 21:35:30","AP02EDTM":"2022-03-10 03:35:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-10","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3685,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.75162,"AVALU":"mg/L","BASE2":9.22447,"BASE":8.75162,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.47285,"PCHG2":-5.12606,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-26 09:35:30","ADY":413,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-173","SUBJID":"id-173","SITEID":"NGA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.99723,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-03-08","TRTSDTM":"2019-03-10 09:35:30","TRTEDTM":"2022-03-10 03:35:30","TRT01SDTM":"2019-03-10 09:35:30","TRT01EDTM":"2021-03-09 21:35:30","TRT02SDTM":"2021-03-09 21:35:30","TRT02EDTM":"2022-03-10 03:35:30","AP01SDTM":"2019-03-10 09:35:30","AP01EDTM":"2021-03-09 21:35:30","AP02SDTM":"2021-03-09 21:35:30","AP02EDTM":"2022-03-10 03:35:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-10","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7051,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.20677,"AVALU":"mg/L","BASE2":9.22447,"BASE":8.75162,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.9823,"PCHG2":10.64883,"CHG":1.45515,"PCHG":16.62721,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-08-21 09:35:30","ADY":530,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-173","SUBJID":"id-173","SITEID":"NGA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.99723,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-03-08","TRTSDTM":"2019-03-10 09:35:30","TRTEDTM":"2022-03-10 03:35:30","TRT01SDTM":"2019-03-10 09:35:30","TRT01EDTM":"2021-03-09 21:35:30","TRT02SDTM":"2021-03-09 21:35:30","TRT02EDTM":"2022-03-10 03:35:30","AP01SDTM":"2019-03-10 09:35:30","AP01EDTM":"2021-03-09 21:35:30","AP02SDTM":"2021-03-09 21:35:30","AP02EDTM":"2022-03-10 03:35:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-10","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6267,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.62524,"AVALU":"mg/L","BASE2":9.22447,"BASE":8.75162,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.59923,"PCHG2":-6.49606,"CHG":-0.12637,"PCHG":-1.44402,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-24 09:35:30","ADY":686,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-173","SUBJID":"id-173","SITEID":"NGA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.99723,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-03-08","TRTSDTM":"2019-03-10 09:35:30","TRTEDTM":"2022-03-10 03:35:30","TRT01SDTM":"2019-03-10 09:35:30","TRT01EDTM":"2021-03-09 21:35:30","TRT02SDTM":"2021-03-09 21:35:30","TRT02EDTM":"2022-03-10 03:35:30","AP01SDTM":"2019-03-10 09:35:30","AP01EDTM":"2021-03-09 21:35:30","AP02SDTM":"2021-03-09 21:35:30","AP02EDTM":"2022-03-10 03:35:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-10","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3705,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.96338,"AVALU":"mg/L","BASE2":9.22447,"BASE":8.75162,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.26109,"PCHG2":-2.83037,"CHG":0.21177,"PCHG":2.41973,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-27 09:35:30","ADY":870,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-173","SUBJID":"id-173","SITEID":"NGA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.99723,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-03-08","TRTSDTM":"2019-03-10 09:35:30","TRTEDTM":"2022-03-10 03:35:30","TRT01SDTM":"2019-03-10 09:35:30","TRT01EDTM":"2021-03-09 21:35:30","TRT02SDTM":"2021-03-09 21:35:30","TRT02EDTM":"2022-03-10 03:35:30","AP01SDTM":"2019-03-10 09:35:30","AP01EDTM":"2021-03-09 21:35:30","AP02SDTM":"2021-03-09 21:35:30","AP02EDTM":"2022-03-10 03:35:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-10","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":660,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.55918,"AVALU":"mg/L","BASE2":9.22447,"BASE":8.75162,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.66529,"PCHG2":-7.21222,"CHG":-0.19244,"PCHG":-2.19888,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-07 09:35:30","ADY":881,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-173","SUBJID":"id-173","SITEID":"NGA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.99723,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-03-08","TRTSDTM":"2019-03-10 09:35:30","TRTEDTM":"2022-03-10 03:35:30","TRT01SDTM":"2019-03-10 09:35:30","TRT01EDTM":"2021-03-09 21:35:30","TRT02SDTM":"2021-03-09 21:35:30","TRT02EDTM":"2022-03-10 03:35:30","AP01SDTM":"2019-03-10 09:35:30","AP01EDTM":"2021-03-09 21:35:30","AP02SDTM":"2021-03-09 21:35:30","AP02EDTM":"2022-03-10 03:35:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-10","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4465,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.05908,"AVALU":"mg/L","BASE2":9.22447,"BASE":8.75162,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16538,"PCHG2":-1.79287,"CHG":0.30747,"PCHG":3.51328,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-20 09:35:30","ADY":1078,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-173","SUBJID":"id-173","SITEID":"NGA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.99723,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-03-08","TRTSDTM":"2019-03-10 09:35:30","TRTEDTM":"2022-03-10 03:35:30","TRT01SDTM":"2019-03-10 09:35:30","TRT01EDTM":"2021-03-09 21:35:30","TRT02SDTM":"2021-03-09 21:35:30","TRT02EDTM":"2022-03-10 03:35:30","AP01SDTM":"2019-03-10 09:35:30","AP01EDTM":"2021-03-09 21:35:30","AP02SDTM":"2021-03-09 21:35:30","AP02EDTM":"2022-03-10 03:35:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-10","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3571,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87692,"AVALU":"g/L","BASE2":2.87692,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-30 09:35:30","ADY":295,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-173","SUBJID":"id-173","SITEID":"NGA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.99723,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-03-08","TRTSDTM":"2019-03-10 09:35:30","TRTEDTM":"2022-03-10 03:35:30","TRT01SDTM":"2019-03-10 09:35:30","TRT01EDTM":"2021-03-09 21:35:30","TRT02SDTM":"2021-03-09 21:35:30","TRT02EDTM":"2022-03-10 03:35:30","AP01SDTM":"2019-03-10 09:35:30","AP01EDTM":"2021-03-09 21:35:30","AP02SDTM":"2021-03-09 21:35:30","AP02EDTM":"2022-03-10 03:35:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-10","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6964,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8967,"AVALU":"g/L","BASE2":2.87692,"BASE":2.8967,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.01978,"PCHG2":0.68765,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-26 09:35:30","ADY":413,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-173","SUBJID":"id-173","SITEID":"NGA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.99723,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-03-08","TRTSDTM":"2019-03-10 09:35:30","TRTEDTM":"2022-03-10 03:35:30","TRT01SDTM":"2019-03-10 09:35:30","TRT01EDTM":"2021-03-09 21:35:30","TRT02SDTM":"2021-03-09 21:35:30","TRT02EDTM":"2022-03-10 03:35:30","AP01SDTM":"2019-03-10 09:35:30","AP01EDTM":"2021-03-09 21:35:30","AP02SDTM":"2021-03-09 21:35:30","AP02EDTM":"2022-03-10 03:35:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-10","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":838,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.1031,"AVALU":"g/L","BASE2":2.87692,"BASE":2.8967,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.22619,"PCHG2":7.86213,"CHG":0.2064,"PCHG":7.12548,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-08-21 09:35:30","ADY":530,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-173","SUBJID":"id-173","SITEID":"NGA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.99723,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-03-08","TRTSDTM":"2019-03-10 09:35:30","TRTEDTM":"2022-03-10 03:35:30","TRT01SDTM":"2019-03-10 09:35:30","TRT01EDTM":"2021-03-09 21:35:30","TRT02SDTM":"2021-03-09 21:35:30","TRT02EDTM":"2022-03-10 03:35:30","AP01SDTM":"2019-03-10 09:35:30","AP01EDTM":"2021-03-09 21:35:30","AP02SDTM":"2021-03-09 21:35:30","AP02EDTM":"2022-03-10 03:35:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-10","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":641,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78324,"AVALU":"g/L","BASE2":2.87692,"BASE":2.8967,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09368,"PCHG2":-3.2561,"CHG":-0.11346,"PCHG":-3.91682,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-24 09:35:30","ADY":686,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-173","SUBJID":"id-173","SITEID":"NGA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.99723,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-03-08","TRTSDTM":"2019-03-10 09:35:30","TRTEDTM":"2022-03-10 03:35:30","TRT01SDTM":"2019-03-10 09:35:30","TRT01EDTM":"2021-03-09 21:35:30","TRT02SDTM":"2021-03-09 21:35:30","TRT02EDTM":"2022-03-10 03:35:30","AP01SDTM":"2019-03-10 09:35:30","AP01EDTM":"2021-03-09 21:35:30","AP02SDTM":"2021-03-09 21:35:30","AP02EDTM":"2022-03-10 03:35:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-10","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6091,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0205,"AVALU":"g/L","BASE2":2.87692,"BASE":2.8967,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14359,"PCHG2":4.99102,"CHG":0.1238,"PCHG":4.27398,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-07-27 09:35:30","ADY":870,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-173","SUBJID":"id-173","SITEID":"NGA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.99723,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-03-08","TRTSDTM":"2019-03-10 09:35:30","TRTEDTM":"2022-03-10 03:35:30","TRT01SDTM":"2019-03-10 09:35:30","TRT01EDTM":"2021-03-09 21:35:30","TRT02SDTM":"2021-03-09 21:35:30","TRT02EDTM":"2022-03-10 03:35:30","AP01SDTM":"2019-03-10 09:35:30","AP01EDTM":"2021-03-09 21:35:30","AP02SDTM":"2021-03-09 21:35:30","AP02EDTM":"2022-03-10 03:35:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-10","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6349,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81448,"AVALU":"g/L","BASE2":2.87692,"BASE":2.8967,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06244,"PCHG2":-2.17024,"CHG":-0.08222,"PCHG":-2.83837,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-07 09:35:30","ADY":881,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-173","SUBJID":"id-173","SITEID":"NGA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.99723,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-03-08","TRTSDTM":"2019-03-10 09:35:30","TRTEDTM":"2022-03-10 03:35:30","TRT01SDTM":"2019-03-10 09:35:30","TRT01EDTM":"2021-03-09 21:35:30","TRT02SDTM":"2021-03-09 21:35:30","TRT02EDTM":"2022-03-10 03:35:30","AP01SDTM":"2019-03-10 09:35:30","AP01EDTM":"2021-03-09 21:35:30","AP02SDTM":"2021-03-09 21:35:30","AP02EDTM":"2022-03-10 03:35:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-10","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":64,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92267,"AVALU":"g/L","BASE2":2.87692,"BASE":2.8967,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04575,"PCHG2":1.59024,"CHG":0.02597,"PCHG":0.89642,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-20 09:35:30","ADY":1078,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-313","SUBJID":"id-313","SITEID":"NGA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.91108,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 18:44:09","TRTEDTM":"2022-05-12 12:44:09","TRT01SDTM":"2019-05-12 18:44:09","TRT01EDTM":"2021-05-12 06:44:09","TRT02SDTM":"2021-05-12 06:44:09","TRT02EDTM":"2022-05-12 12:44:09","AP01SDTM":"2019-05-12 18:44:09","AP01EDTM":"2021-05-12 06:44:09","AP02SDTM":"2021-05-12 06:44:09","AP02EDTM":"2022-05-12 12:44:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-12","EOSDY":1096,"LSTALVDT":"2022-05-24","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2134,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.35476,"AVALU":"U/L","BASE2":16.35476,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-19 18:44:09","ADY":343,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-313","SUBJID":"id-313","SITEID":"NGA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.91108,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 18:44:09","TRTEDTM":"2022-05-12 12:44:09","TRT01SDTM":"2019-05-12 18:44:09","TRT01EDTM":"2021-05-12 06:44:09","TRT02SDTM":"2021-05-12 06:44:09","TRT02EDTM":"2022-05-12 12:44:09","AP01SDTM":"2019-05-12 18:44:09","AP01EDTM":"2021-05-12 06:44:09","AP02SDTM":"2021-05-12 06:44:09","AP02EDTM":"2022-05-12 12:44:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-12","EOSDY":1096,"LSTALVDT":"2022-05-24","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2741,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.69095,"AVALU":"U/L","BASE2":16.35476,"BASE":18.69095,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.33618,"PCHG2":14.28441,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-06 18:44:09","ADY":636,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-313","SUBJID":"id-313","SITEID":"NGA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.91108,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 18:44:09","TRTEDTM":"2022-05-12 12:44:09","TRT01SDTM":"2019-05-12 18:44:09","TRT01EDTM":"2021-05-12 06:44:09","TRT02SDTM":"2021-05-12 06:44:09","TRT02EDTM":"2022-05-12 12:44:09","AP01SDTM":"2019-05-12 18:44:09","AP01EDTM":"2021-05-12 06:44:09","AP02SDTM":"2021-05-12 06:44:09","AP02EDTM":"2022-05-12 12:44:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-12","EOSDY":1096,"LSTALVDT":"2022-05-24","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1852,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.72139,"AVALU":"U/L","BASE2":16.35476,"BASE":18.69095,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.63338,"PCHG2":-40.5593,"CHG":-8.96956,"PCHG":-47.98879,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-16 18:44:09","ADY":735,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-313","SUBJID":"id-313","SITEID":"NGA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.91108,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 18:44:09","TRTEDTM":"2022-05-12 12:44:09","TRT01SDTM":"2019-05-12 18:44:09","TRT01EDTM":"2021-05-12 06:44:09","TRT02SDTM":"2021-05-12 06:44:09","TRT02EDTM":"2022-05-12 12:44:09","AP01SDTM":"2019-05-12 18:44:09","AP01EDTM":"2021-05-12 06:44:09","AP02SDTM":"2021-05-12 06:44:09","AP02EDTM":"2022-05-12 12:44:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-12","EOSDY":1096,"LSTALVDT":"2022-05-24","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5346,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.63311,"AVALU":"U/L","BASE2":16.35476,"BASE":18.69095,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.72166,"PCHG2":-22.75579,"CHG":-6.05784,"PCHG":-32.41054,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-05 18:44:09","ADY":816,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-313","SUBJID":"id-313","SITEID":"NGA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.91108,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 18:44:09","TRTEDTM":"2022-05-12 12:44:09","TRT01SDTM":"2019-05-12 18:44:09","TRT01EDTM":"2021-05-12 06:44:09","TRT02SDTM":"2021-05-12 06:44:09","TRT02EDTM":"2022-05-12 12:44:09","AP01SDTM":"2019-05-12 18:44:09","AP01EDTM":"2021-05-12 06:44:09","AP02SDTM":"2021-05-12 06:44:09","AP02EDTM":"2022-05-12 12:44:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-12","EOSDY":1096,"LSTALVDT":"2022-05-24","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5984,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.03571,"AVALU":"U/L","BASE2":16.35476,"BASE":18.69095,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.68095,"PCHG2":46.96457,"CHG":5.34476,"PCHG":28.59547,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-31 18:44:09","ADY":903,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-313","SUBJID":"id-313","SITEID":"NGA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.91108,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 18:44:09","TRTEDTM":"2022-05-12 12:44:09","TRT01SDTM":"2019-05-12 18:44:09","TRT01EDTM":"2021-05-12 06:44:09","TRT02SDTM":"2021-05-12 06:44:09","TRT02EDTM":"2022-05-12 12:44:09","AP01SDTM":"2019-05-12 18:44:09","AP01EDTM":"2021-05-12 06:44:09","AP02SDTM":"2021-05-12 06:44:09","AP02EDTM":"2022-05-12 12:44:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-12","EOSDY":1096,"LSTALVDT":"2022-05-24","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5432,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.11143,"AVALU":"U/L","BASE2":16.35476,"BASE":18.69095,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.75666,"PCHG2":102.45739,"CHG":14.42048,"PCHG":77.15223,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-08 18:44:09","ADY":1062,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-313","SUBJID":"id-313","SITEID":"NGA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.91108,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 18:44:09","TRTEDTM":"2022-05-12 12:44:09","TRT01SDTM":"2019-05-12 18:44:09","TRT01EDTM":"2021-05-12 06:44:09","TRT02SDTM":"2021-05-12 06:44:09","TRT02EDTM":"2022-05-12 12:44:09","AP01SDTM":"2019-05-12 18:44:09","AP01EDTM":"2021-05-12 06:44:09","AP02SDTM":"2021-05-12 06:44:09","AP02EDTM":"2022-05-12 12:44:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-12","EOSDY":1096,"LSTALVDT":"2022-05-24","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3953,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.69856,"AVALU":"U/L","BASE2":16.35476,"BASE":18.69095,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.65621,"PCHG2":-52.92775,"CHG":-10.99239,"PCHG":-58.81131,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-30 18:44:09","ADY":1084,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-313","SUBJID":"id-313","SITEID":"NGA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.91108,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 18:44:09","TRTEDTM":"2022-05-12 12:44:09","TRT01SDTM":"2019-05-12 18:44:09","TRT01EDTM":"2021-05-12 06:44:09","TRT02SDTM":"2021-05-12 06:44:09","TRT02EDTM":"2022-05-12 12:44:09","AP01SDTM":"2019-05-12 18:44:09","AP01EDTM":"2021-05-12 06:44:09","AP02SDTM":"2021-05-12 06:44:09","AP02EDTM":"2022-05-12 12:44:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-12","EOSDY":1096,"LSTALVDT":"2022-05-24","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6126,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.43323,"AVALU":"mg/L","BASE2":8.43323,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-19 18:44:09","ADY":343,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-313","SUBJID":"id-313","SITEID":"NGA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.91108,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 18:44:09","TRTEDTM":"2022-05-12 12:44:09","TRT01SDTM":"2019-05-12 18:44:09","TRT01EDTM":"2021-05-12 06:44:09","TRT02SDTM":"2021-05-12 06:44:09","TRT02EDTM":"2022-05-12 12:44:09","AP01SDTM":"2019-05-12 18:44:09","AP01EDTM":"2021-05-12 06:44:09","AP02SDTM":"2021-05-12 06:44:09","AP02EDTM":"2022-05-12 12:44:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-12","EOSDY":1096,"LSTALVDT":"2022-05-24","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1348,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.72215,"AVALU":"mg/L","BASE2":8.43323,"BASE":9.72215,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.28892,"PCHG2":15.28382,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-06 18:44:09","ADY":636,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-313","SUBJID":"id-313","SITEID":"NGA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.91108,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 18:44:09","TRTEDTM":"2022-05-12 12:44:09","TRT01SDTM":"2019-05-12 18:44:09","TRT01EDTM":"2021-05-12 06:44:09","TRT02SDTM":"2021-05-12 06:44:09","TRT02EDTM":"2022-05-12 12:44:09","AP01SDTM":"2019-05-12 18:44:09","AP01EDTM":"2021-05-12 06:44:09","AP02SDTM":"2021-05-12 06:44:09","AP02EDTM":"2022-05-12 12:44:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-12","EOSDY":1096,"LSTALVDT":"2022-05-24","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7657,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.48558,"AVALU":"mg/L","BASE2":8.43323,"BASE":9.72215,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.94765,"PCHG2":-11.23708,"CHG":-2.23657,"PCHG":-23.00488,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-05-16 18:44:09","ADY":735,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-313","SUBJID":"id-313","SITEID":"NGA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.91108,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 18:44:09","TRTEDTM":"2022-05-12 12:44:09","TRT01SDTM":"2019-05-12 18:44:09","TRT01EDTM":"2021-05-12 06:44:09","TRT02SDTM":"2021-05-12 06:44:09","TRT02EDTM":"2022-05-12 12:44:09","AP01SDTM":"2019-05-12 18:44:09","AP01EDTM":"2021-05-12 06:44:09","AP02SDTM":"2021-05-12 06:44:09","AP02EDTM":"2022-05-12 12:44:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-12","EOSDY":1096,"LSTALVDT":"2022-05-24","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7538,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.06294,"AVALU":"mg/L","BASE2":8.43323,"BASE":9.72215,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.37029,"PCHG2":-4.39086,"CHG":-1.65921,"PCHG":-17.0663,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-05 18:44:09","ADY":816,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-313","SUBJID":"id-313","SITEID":"NGA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.91108,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 18:44:09","TRTEDTM":"2022-05-12 12:44:09","TRT01SDTM":"2019-05-12 18:44:09","TRT01EDTM":"2021-05-12 06:44:09","TRT02SDTM":"2021-05-12 06:44:09","TRT02EDTM":"2022-05-12 12:44:09","AP01SDTM":"2019-05-12 18:44:09","AP01EDTM":"2021-05-12 06:44:09","AP02SDTM":"2021-05-12 06:44:09","AP02EDTM":"2022-05-12 12:44:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-12","EOSDY":1096,"LSTALVDT":"2022-05-24","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3189,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.69997,"AVALU":"mg/L","BASE2":8.43323,"BASE":9.72215,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.26674,"PCHG2":15.02076,"CHG":-0.02218,"PCHG":-0.22818,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-31 18:44:09","ADY":903,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-313","SUBJID":"id-313","SITEID":"NGA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.91108,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 18:44:09","TRTEDTM":"2022-05-12 12:44:09","TRT01SDTM":"2019-05-12 18:44:09","TRT01EDTM":"2021-05-12 06:44:09","TRT02SDTM":"2021-05-12 06:44:09","TRT02EDTM":"2022-05-12 12:44:09","AP01SDTM":"2019-05-12 18:44:09","AP01EDTM":"2021-05-12 06:44:09","AP02SDTM":"2021-05-12 06:44:09","AP02EDTM":"2022-05-12 12:44:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-12","EOSDY":1096,"LSTALVDT":"2022-05-24","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4482,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.24826,"AVALU":"mg/L","BASE2":8.43323,"BASE":9.72215,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18497,"PCHG2":-2.19336,"CHG":-1.47389,"PCHG":-15.16014,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-08 18:44:09","ADY":1062,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-313","SUBJID":"id-313","SITEID":"NGA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.91108,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 18:44:09","TRTEDTM":"2022-05-12 12:44:09","TRT01SDTM":"2019-05-12 18:44:09","TRT01EDTM":"2021-05-12 06:44:09","TRT02SDTM":"2021-05-12 06:44:09","TRT02EDTM":"2022-05-12 12:44:09","AP01SDTM":"2019-05-12 18:44:09","AP01EDTM":"2021-05-12 06:44:09","AP02SDTM":"2021-05-12 06:44:09","AP02EDTM":"2022-05-12 12:44:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-12","EOSDY":1096,"LSTALVDT":"2022-05-24","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1652,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.94295,"AVALU":"mg/L","BASE2":8.43323,"BASE":9.72215,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.50972,"PCHG2":6.04413,"CHG":-0.7792,"PCHG":-8.01473,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-30 18:44:09","ADY":1084,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-313","SUBJID":"id-313","SITEID":"NGA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.91108,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 18:44:09","TRTEDTM":"2022-05-12 12:44:09","TRT01SDTM":"2019-05-12 18:44:09","TRT01EDTM":"2021-05-12 06:44:09","TRT02SDTM":"2021-05-12 06:44:09","TRT02EDTM":"2022-05-12 12:44:09","AP01SDTM":"2019-05-12 18:44:09","AP01EDTM":"2021-05-12 06:44:09","AP02SDTM":"2021-05-12 06:44:09","AP02EDTM":"2022-05-12 12:44:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-12","EOSDY":1096,"LSTALVDT":"2022-05-24","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6133,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.62526,"AVALU":"g/L","BASE2":2.62526,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"4","ADTM":"2020-04-19 18:44:09","ADY":343,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-313","SUBJID":"id-313","SITEID":"NGA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.91108,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 18:44:09","TRTEDTM":"2022-05-12 12:44:09","TRT01SDTM":"2019-05-12 18:44:09","TRT01EDTM":"2021-05-12 06:44:09","TRT02SDTM":"2021-05-12 06:44:09","TRT02EDTM":"2022-05-12 12:44:09","AP01SDTM":"2019-05-12 18:44:09","AP01EDTM":"2021-05-12 06:44:09","AP02SDTM":"2021-05-12 06:44:09","AP02EDTM":"2022-05-12 12:44:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-12","EOSDY":1096,"LSTALVDT":"2022-05-24","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1578,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00868,"AVALU":"g/L","BASE2":2.62526,"BASE":3.00868,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.38342,"PCHG2":14.60492,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"4","BTOXGR":"4","ADTM":"2021-02-06 18:44:09","ADY":636,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-313","SUBJID":"id-313","SITEID":"NGA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.91108,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 18:44:09","TRTEDTM":"2022-05-12 12:44:09","TRT01SDTM":"2019-05-12 18:44:09","TRT01EDTM":"2021-05-12 06:44:09","TRT02SDTM":"2021-05-12 06:44:09","TRT02EDTM":"2022-05-12 12:44:09","AP01SDTM":"2019-05-12 18:44:09","AP01EDTM":"2021-05-12 06:44:09","AP02SDTM":"2021-05-12 06:44:09","AP02EDTM":"2022-05-12 12:44:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-12","EOSDY":1096,"LSTALVDT":"2022-05-24","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2506,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.08751,"AVALU":"g/L","BASE2":2.62526,"BASE":3.00868,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.46225,"PCHG2":17.60772,"CHG":0.07883,"PCHG":2.62013,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"4","ADTM":"2021-05-16 18:44:09","ADY":735,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-313","SUBJID":"id-313","SITEID":"NGA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.91108,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 18:44:09","TRTEDTM":"2022-05-12 12:44:09","TRT01SDTM":"2019-05-12 18:44:09","TRT01EDTM":"2021-05-12 06:44:09","TRT02SDTM":"2021-05-12 06:44:09","TRT02EDTM":"2022-05-12 12:44:09","AP01SDTM":"2019-05-12 18:44:09","AP01EDTM":"2021-05-12 06:44:09","AP02SDTM":"2021-05-12 06:44:09","AP02EDTM":"2022-05-12 12:44:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-12","EOSDY":1096,"LSTALVDT":"2022-05-24","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7240,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89765,"AVALU":"g/L","BASE2":2.62526,"BASE":3.00868,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.27239,"PCHG2":10.37581,"CHG":-0.11103,"PCHG":-3.69016,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2021-08-05 18:44:09","ADY":816,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-313","SUBJID":"id-313","SITEID":"NGA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.91108,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 18:44:09","TRTEDTM":"2022-05-12 12:44:09","TRT01SDTM":"2019-05-12 18:44:09","TRT01EDTM":"2021-05-12 06:44:09","TRT02SDTM":"2021-05-12 06:44:09","TRT02EDTM":"2022-05-12 12:44:09","AP01SDTM":"2019-05-12 18:44:09","AP01EDTM":"2021-05-12 06:44:09","AP02SDTM":"2021-05-12 06:44:09","AP02EDTM":"2022-05-12 12:44:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-12","EOSDY":1096,"LSTALVDT":"2022-05-24","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2721,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05332,"AVALU":"g/L","BASE2":2.62526,"BASE":3.00868,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.42806,"PCHG2":16.3053,"CHG":0.04464,"PCHG":1.48369,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"1","BTOXGR":"4","ADTM":"2021-10-31 18:44:09","ADY":903,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-313","SUBJID":"id-313","SITEID":"NGA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.91108,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 18:44:09","TRTEDTM":"2022-05-12 12:44:09","TRT01SDTM":"2019-05-12 18:44:09","TRT01EDTM":"2021-05-12 06:44:09","TRT02SDTM":"2021-05-12 06:44:09","TRT02EDTM":"2022-05-12 12:44:09","AP01SDTM":"2019-05-12 18:44:09","AP01EDTM":"2021-05-12 06:44:09","AP02SDTM":"2021-05-12 06:44:09","AP02EDTM":"2022-05-12 12:44:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-12","EOSDY":1096,"LSTALVDT":"2022-05-24","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1473,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94774,"AVALU":"g/L","BASE2":2.62526,"BASE":3.00868,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.32248,"PCHG2":12.28384,"CHG":-0.06093,"PCHG":-2.02529,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2022-04-08 18:44:09","ADY":1062,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-313","SUBJID":"id-313","SITEID":"NGA-11","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":2.91108,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 18:44:09","TRTEDTM":"2022-05-12 12:44:09","TRT01SDTM":"2019-05-12 18:44:09","TRT01EDTM":"2021-05-12 06:44:09","TRT02SDTM":"2021-05-12 06:44:09","TRT02EDTM":"2022-05-12 12:44:09","AP01SDTM":"2019-05-12 18:44:09","AP01EDTM":"2021-05-12 06:44:09","AP02SDTM":"2021-05-12 06:44:09","AP02EDTM":"2022-05-12 12:44:09","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-12","EOSDY":1096,"LSTALVDT":"2022-05-24","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3863,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94064,"AVALU":"g/L","BASE2":2.62526,"BASE":3.00868,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.31538,"PCHG2":12.0131,"CHG":-0.06804,"PCHG":-2.26152,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"4","ADTM":"2022-04-30 18:44:09","ADY":1084,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"4","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-334","SUBJID":"id-334","SITEID":"NGA-11","AGE":20,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":2.90932,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-16","TRTSDTM":"2021-01-16 09:01:10","TRTEDTM":"2024-01-17 03:01:10","TRT01SDTM":"2021-01-16 09:01:10","TRT01EDTM":"2023-01-16 21:01:10","TRT02SDTM":"2023-01-16 21:01:10","TRT02EDTM":"2024-01-17 03:01:10","AP01SDTM":"2021-01-16 09:01:10","AP01EDTM":"2023-01-16 21:01:10","AP02SDTM":"2023-01-16 21:01:10","AP02EDTM":"2024-01-17 03:01:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-17","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2320,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.44846,"AVALU":"U/L","BASE2":21.44846,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-28 09:01:10","ADY":163,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-334","SUBJID":"id-334","SITEID":"NGA-11","AGE":20,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":2.90932,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-16","TRTSDTM":"2021-01-16 09:01:10","TRTEDTM":"2024-01-17 03:01:10","TRT01SDTM":"2021-01-16 09:01:10","TRT01EDTM":"2023-01-16 21:01:10","TRT02SDTM":"2023-01-16 21:01:10","TRT02EDTM":"2024-01-17 03:01:10","AP01SDTM":"2021-01-16 09:01:10","AP01EDTM":"2023-01-16 21:01:10","AP02SDTM":"2023-01-16 21:01:10","AP02EDTM":"2024-01-17 03:01:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-17","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8266,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.01309,"AVALU":"U/L","BASE2":21.44846,"BASE":24.01309,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.56463,"PCHG2":11.95718,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-10 09:01:10","ADY":175,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-334","SUBJID":"id-334","SITEID":"NGA-11","AGE":20,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":2.90932,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-16","TRTSDTM":"2021-01-16 09:01:10","TRTEDTM":"2024-01-17 03:01:10","TRT01SDTM":"2021-01-16 09:01:10","TRT01EDTM":"2023-01-16 21:01:10","TRT02SDTM":"2023-01-16 21:01:10","TRT02EDTM":"2024-01-17 03:01:10","AP01SDTM":"2021-01-16 09:01:10","AP01EDTM":"2023-01-16 21:01:10","AP02SDTM":"2023-01-16 21:01:10","AP02EDTM":"2024-01-17 03:01:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-17","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2514,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.21701,"AVALU":"U/L","BASE2":21.44846,"BASE":24.01309,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.76855,"PCHG2":54.869,"CHG":9.20392,"PCHG":38.32878,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-22 09:01:10","ADY":310,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-334","SUBJID":"id-334","SITEID":"NGA-11","AGE":20,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":2.90932,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-16","TRTSDTM":"2021-01-16 09:01:10","TRTEDTM":"2024-01-17 03:01:10","TRT01SDTM":"2021-01-16 09:01:10","TRT01EDTM":"2023-01-16 21:01:10","TRT02SDTM":"2023-01-16 21:01:10","TRT02EDTM":"2024-01-17 03:01:10","AP01SDTM":"2021-01-16 09:01:10","AP01EDTM":"2023-01-16 21:01:10","AP02SDTM":"2023-01-16 21:01:10","AP02EDTM":"2024-01-17 03:01:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-17","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4741,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.14119,"AVALU":"U/L","BASE2":21.44846,"BASE":24.01309,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.30727,"PCHG2":-48.05598,"CHG":-12.8719,"PCHG":-53.60367,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-09 09:01:10","ADY":417,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-334","SUBJID":"id-334","SITEID":"NGA-11","AGE":20,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":2.90932,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-16","TRTSDTM":"2021-01-16 09:01:10","TRTEDTM":"2024-01-17 03:01:10","TRT01SDTM":"2021-01-16 09:01:10","TRT01EDTM":"2023-01-16 21:01:10","TRT02SDTM":"2023-01-16 21:01:10","TRT02EDTM":"2024-01-17 03:01:10","AP01SDTM":"2021-01-16 09:01:10","AP01EDTM":"2023-01-16 21:01:10","AP02SDTM":"2023-01-16 21:01:10","AP02EDTM":"2024-01-17 03:01:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-17","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2112,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":36.14546,"AVALU":"U/L","BASE2":21.44846,"BASE":24.01309,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.697,"PCHG2":68.52242,"CHG":12.13237,"PCHG":50.52399,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-03 09:01:10","ADY":442,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-334","SUBJID":"id-334","SITEID":"NGA-11","AGE":20,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":2.90932,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-16","TRTSDTM":"2021-01-16 09:01:10","TRTEDTM":"2024-01-17 03:01:10","TRT01SDTM":"2021-01-16 09:01:10","TRT01EDTM":"2023-01-16 21:01:10","TRT02SDTM":"2023-01-16 21:01:10","TRT02EDTM":"2024-01-17 03:01:10","AP01SDTM":"2021-01-16 09:01:10","AP01EDTM":"2023-01-16 21:01:10","AP02SDTM":"2023-01-16 21:01:10","AP02EDTM":"2024-01-17 03:01:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-17","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1252,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.71175,"AVALU":"U/L","BASE2":21.44846,"BASE":24.01309,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.73671,"PCHG2":-36.07117,"CHG":-10.30134,"PCHG":-42.89885,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-11 09:01:10","ADY":572,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-334","SUBJID":"id-334","SITEID":"NGA-11","AGE":20,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":2.90932,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-16","TRTSDTM":"2021-01-16 09:01:10","TRTEDTM":"2024-01-17 03:01:10","TRT01SDTM":"2021-01-16 09:01:10","TRT01EDTM":"2023-01-16 21:01:10","TRT02SDTM":"2023-01-16 21:01:10","TRT02EDTM":"2024-01-17 03:01:10","AP01SDTM":"2021-01-16 09:01:10","AP01EDTM":"2023-01-16 21:01:10","AP02SDTM":"2023-01-16 21:01:10","AP02EDTM":"2024-01-17 03:01:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-17","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5560,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.55734,"AVALU":"U/L","BASE2":21.44846,"BASE":24.01309,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.89112,"PCHG2":-22.80406,"CHG":-7.45575,"PCHG":-31.0487,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-01 09:01:10","ADY":866,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-334","SUBJID":"id-334","SITEID":"NGA-11","AGE":20,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":2.90932,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-16","TRTSDTM":"2021-01-16 09:01:10","TRTEDTM":"2024-01-17 03:01:10","TRT01SDTM":"2021-01-16 09:01:10","TRT01EDTM":"2023-01-16 21:01:10","TRT02SDTM":"2023-01-16 21:01:10","TRT02EDTM":"2024-01-17 03:01:10","AP01SDTM":"2021-01-16 09:01:10","AP01EDTM":"2023-01-16 21:01:10","AP02SDTM":"2023-01-16 21:01:10","AP02EDTM":"2024-01-17 03:01:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-17","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3128,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.40048,"AVALU":"mg/L","BASE2":8.40048,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-28 09:01:10","ADY":163,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-334","SUBJID":"id-334","SITEID":"NGA-11","AGE":20,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":2.90932,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-16","TRTSDTM":"2021-01-16 09:01:10","TRTEDTM":"2024-01-17 03:01:10","TRT01SDTM":"2021-01-16 09:01:10","TRT01EDTM":"2023-01-16 21:01:10","TRT02SDTM":"2023-01-16 21:01:10","TRT02EDTM":"2024-01-17 03:01:10","AP01SDTM":"2021-01-16 09:01:10","AP01EDTM":"2023-01-16 21:01:10","AP02SDTM":"2023-01-16 21:01:10","AP02EDTM":"2024-01-17 03:01:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-17","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3041,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.52418,"AVALU":"mg/L","BASE2":8.40048,"BASE":9.52418,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.1237,"PCHG2":13.37662,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-10 09:01:10","ADY":175,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-334","SUBJID":"id-334","SITEID":"NGA-11","AGE":20,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":2.90932,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-16","TRTSDTM":"2021-01-16 09:01:10","TRTEDTM":"2024-01-17 03:01:10","TRT01SDTM":"2021-01-16 09:01:10","TRT01EDTM":"2023-01-16 21:01:10","TRT02SDTM":"2023-01-16 21:01:10","TRT02EDTM":"2024-01-17 03:01:10","AP01SDTM":"2021-01-16 09:01:10","AP01EDTM":"2023-01-16 21:01:10","AP02SDTM":"2023-01-16 21:01:10","AP02EDTM":"2024-01-17 03:01:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-17","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5865,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.1112,"AVALU":"mg/L","BASE2":8.40048,"BASE":9.52418,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.71073,"PCHG2":20.36462,"CHG":0.58703,"PCHG":6.16353,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-11-22 09:01:10","ADY":310,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-334","SUBJID":"id-334","SITEID":"NGA-11","AGE":20,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":2.90932,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-16","TRTSDTM":"2021-01-16 09:01:10","TRTEDTM":"2024-01-17 03:01:10","TRT01SDTM":"2021-01-16 09:01:10","TRT01EDTM":"2023-01-16 21:01:10","TRT02SDTM":"2023-01-16 21:01:10","TRT02EDTM":"2024-01-17 03:01:10","AP01SDTM":"2021-01-16 09:01:10","AP01EDTM":"2023-01-16 21:01:10","AP02SDTM":"2023-01-16 21:01:10","AP02EDTM":"2024-01-17 03:01:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-17","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6139,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.67106,"AVALU":"mg/L","BASE2":8.40048,"BASE":9.52418,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.27058,"PCHG2":15.12511,"CHG":0.14688,"PCHG":1.54219,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-09 09:01:10","ADY":417,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-334","SUBJID":"id-334","SITEID":"NGA-11","AGE":20,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":2.90932,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-16","TRTSDTM":"2021-01-16 09:01:10","TRTEDTM":"2024-01-17 03:01:10","TRT01SDTM":"2021-01-16 09:01:10","TRT01EDTM":"2023-01-16 21:01:10","TRT02SDTM":"2023-01-16 21:01:10","TRT02EDTM":"2024-01-17 03:01:10","AP01SDTM":"2021-01-16 09:01:10","AP01EDTM":"2023-01-16 21:01:10","AP02SDTM":"2023-01-16 21:01:10","AP02EDTM":"2024-01-17 03:01:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-17","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2801,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.09338,"AVALU":"mg/L","BASE2":8.40048,"BASE":9.52418,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.3071,"PCHG2":-3.65576,"CHG":-1.4308,"PCHG":-15.02283,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-03 09:01:10","ADY":442,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-334","SUBJID":"id-334","SITEID":"NGA-11","AGE":20,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":2.90932,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-16","TRTSDTM":"2021-01-16 09:01:10","TRTEDTM":"2024-01-17 03:01:10","TRT01SDTM":"2021-01-16 09:01:10","TRT01EDTM":"2023-01-16 21:01:10","TRT02SDTM":"2023-01-16 21:01:10","TRT02EDTM":"2024-01-17 03:01:10","AP01SDTM":"2021-01-16 09:01:10","AP01EDTM":"2023-01-16 21:01:10","AP02SDTM":"2023-01-16 21:01:10","AP02EDTM":"2024-01-17 03:01:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-17","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6064,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.71983,"AVALU":"mg/L","BASE2":8.40048,"BASE":9.52418,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.31935,"PCHG2":15.70566,"CHG":0.19565,"PCHG":2.05425,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-11 09:01:10","ADY":572,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-334","SUBJID":"id-334","SITEID":"NGA-11","AGE":20,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":2.90932,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-16","TRTSDTM":"2021-01-16 09:01:10","TRTEDTM":"2024-01-17 03:01:10","TRT01SDTM":"2021-01-16 09:01:10","TRT01EDTM":"2023-01-16 21:01:10","TRT02SDTM":"2023-01-16 21:01:10","TRT02EDTM":"2024-01-17 03:01:10","AP01SDTM":"2021-01-16 09:01:10","AP01EDTM":"2023-01-16 21:01:10","AP02SDTM":"2023-01-16 21:01:10","AP02EDTM":"2024-01-17 03:01:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-17","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":481,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.45561,"AVALU":"mg/L","BASE2":8.40048,"BASE":9.52418,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.05513,"PCHG2":12.56032,"CHG":-0.06857,"PCHG":-0.71999,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-01 09:01:10","ADY":866,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-334","SUBJID":"id-334","SITEID":"NGA-11","AGE":20,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":2.90932,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-16","TRTSDTM":"2021-01-16 09:01:10","TRTEDTM":"2024-01-17 03:01:10","TRT01SDTM":"2021-01-16 09:01:10","TRT01EDTM":"2023-01-16 21:01:10","TRT02SDTM":"2023-01-16 21:01:10","TRT02EDTM":"2024-01-17 03:01:10","AP01SDTM":"2021-01-16 09:01:10","AP01EDTM":"2023-01-16 21:01:10","AP02SDTM":"2023-01-16 21:01:10","AP02EDTM":"2024-01-17 03:01:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-17","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3778,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85196,"AVALU":"g/L","BASE2":2.85196,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-06-28 09:01:10","ADY":163,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-334","SUBJID":"id-334","SITEID":"NGA-11","AGE":20,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":2.90932,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-16","TRTSDTM":"2021-01-16 09:01:10","TRTEDTM":"2024-01-17 03:01:10","TRT01SDTM":"2021-01-16 09:01:10","TRT01EDTM":"2023-01-16 21:01:10","TRT02SDTM":"2023-01-16 21:01:10","TRT02EDTM":"2024-01-17 03:01:10","AP01SDTM":"2021-01-16 09:01:10","AP01EDTM":"2023-01-16 21:01:10","AP02SDTM":"2023-01-16 21:01:10","AP02EDTM":"2024-01-17 03:01:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-17","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1625,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02051,"AVALU":"g/L","BASE2":2.85196,"BASE":3.02051,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.16855,"PCHG2":5.90985,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2021-07-10 09:01:10","ADY":175,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-334","SUBJID":"id-334","SITEID":"NGA-11","AGE":20,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":2.90932,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-16","TRTSDTM":"2021-01-16 09:01:10","TRTEDTM":"2024-01-17 03:01:10","TRT01SDTM":"2021-01-16 09:01:10","TRT01EDTM":"2023-01-16 21:01:10","TRT02SDTM":"2023-01-16 21:01:10","TRT02EDTM":"2024-01-17 03:01:10","AP01SDTM":"2021-01-16 09:01:10","AP01EDTM":"2023-01-16 21:01:10","AP02SDTM":"2023-01-16 21:01:10","AP02EDTM":"2024-01-17 03:01:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-17","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1432,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01212,"AVALU":"g/L","BASE2":2.85196,"BASE":3.02051,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16016,"PCHG2":5.61573,"CHG":-0.00839,"PCHG":-0.27771,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"1","BTOXGR":"3","ADTM":"2021-11-22 09:01:10","ADY":310,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-334","SUBJID":"id-334","SITEID":"NGA-11","AGE":20,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":2.90932,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-16","TRTSDTM":"2021-01-16 09:01:10","TRTEDTM":"2024-01-17 03:01:10","TRT01SDTM":"2021-01-16 09:01:10","TRT01EDTM":"2023-01-16 21:01:10","TRT02SDTM":"2023-01-16 21:01:10","TRT02EDTM":"2024-01-17 03:01:10","AP01SDTM":"2021-01-16 09:01:10","AP01EDTM":"2023-01-16 21:01:10","AP02SDTM":"2023-01-16 21:01:10","AP02EDTM":"2024-01-17 03:01:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-17","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4013,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93972,"AVALU":"g/L","BASE2":2.85196,"BASE":3.02051,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08776,"PCHG2":3.07706,"CHG":-0.08079,"PCHG":-2.67472,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-03-09 09:01:10","ADY":417,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-334","SUBJID":"id-334","SITEID":"NGA-11","AGE":20,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":2.90932,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-16","TRTSDTM":"2021-01-16 09:01:10","TRTEDTM":"2024-01-17 03:01:10","TRT01SDTM":"2021-01-16 09:01:10","TRT01EDTM":"2023-01-16 21:01:10","TRT02SDTM":"2023-01-16 21:01:10","TRT02EDTM":"2024-01-17 03:01:10","AP01SDTM":"2021-01-16 09:01:10","AP01EDTM":"2023-01-16 21:01:10","AP02SDTM":"2023-01-16 21:01:10","AP02EDTM":"2024-01-17 03:01:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-17","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2299,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.73822,"AVALU":"g/L","BASE2":2.85196,"BASE":3.02051,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11374,"PCHG2":-3.98816,"CHG":-0.28229,"PCHG":-9.34569,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-04-03 09:01:10","ADY":442,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-334","SUBJID":"id-334","SITEID":"NGA-11","AGE":20,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":2.90932,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-16","TRTSDTM":"2021-01-16 09:01:10","TRTEDTM":"2024-01-17 03:01:10","TRT01SDTM":"2021-01-16 09:01:10","TRT01EDTM":"2023-01-16 21:01:10","TRT02SDTM":"2023-01-16 21:01:10","TRT02EDTM":"2024-01-17 03:01:10","AP01SDTM":"2021-01-16 09:01:10","AP01EDTM":"2023-01-16 21:01:10","AP02SDTM":"2023-01-16 21:01:10","AP02EDTM":"2024-01-17 03:01:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-17","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6537,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99458,"AVALU":"g/L","BASE2":2.85196,"BASE":3.02051,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14262,"PCHG2":5.00071,"CHG":-0.02593,"PCHG":-0.85841,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-08-11 09:01:10","ADY":572,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-334","SUBJID":"id-334","SITEID":"NGA-11","AGE":20,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":2.90932,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-16","TRTSDTM":"2021-01-16 09:01:10","TRTEDTM":"2024-01-17 03:01:10","TRT01SDTM":"2021-01-16 09:01:10","TRT01EDTM":"2023-01-16 21:01:10","TRT02SDTM":"2023-01-16 21:01:10","TRT02EDTM":"2024-01-17 03:01:10","AP01SDTM":"2021-01-16 09:01:10","AP01EDTM":"2023-01-16 21:01:10","AP02SDTM":"2023-01-16 21:01:10","AP02EDTM":"2024-01-17 03:01:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-01-17","EOSDY":1096,"LSTALVDT":"2024-02-04","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5746,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92286,"AVALU":"g/L","BASE2":2.85196,"BASE":3.02051,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0709,"PCHG2":2.486,"CHG":-0.09765,"PCHG":-3.2328,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2023-06-01 09:01:10","ADY":866,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-35","SUBJID":"id-35","SITEID":"NGA-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":9.02841,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-26 05:10:30","TRTEDTM":"2022-02-13 19:35:42","TRT01SDTM":"2019-08-26 05:10:30","TRT01EDTM":"2021-02-13 13:35:42","TRT02SDTM":"2021-02-13 13:35:42","TRT02EDTM":"2022-02-13 19:35:42","AP01SDTM":"2019-08-26 05:10:30","AP01EDTM":"2021-02-13 13:35:42","AP02SDTM":"2021-02-13 13:35:42","AP02EDTM":"2022-02-13 19:35:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":903,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":923,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5185,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.70019,"AVALU":"U/L","BASE2":21.70019,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-02 05:10:30","ADY":37,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-35","SUBJID":"id-35","SITEID":"NGA-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":9.02841,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-26 05:10:30","TRTEDTM":"2022-02-13 19:35:42","TRT01SDTM":"2019-08-26 05:10:30","TRT01EDTM":"2021-02-13 13:35:42","TRT02SDTM":"2021-02-13 13:35:42","TRT02EDTM":"2022-02-13 19:35:42","AP01SDTM":"2019-08-26 05:10:30","AP01EDTM":"2021-02-13 13:35:42","AP02SDTM":"2021-02-13 13:35:42","AP02EDTM":"2022-02-13 19:35:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":903,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":923,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6199,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.77299,"AVALU":"U/L","BASE2":21.70019,"BASE":32.77299,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":11.0728,"PCHG2":51.02629,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-16 05:10:30","ADY":143,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-35","SUBJID":"id-35","SITEID":"NGA-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":9.02841,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-26 05:10:30","TRTEDTM":"2022-02-13 19:35:42","TRT01SDTM":"2019-08-26 05:10:30","TRT01EDTM":"2021-02-13 13:35:42","TRT02SDTM":"2021-02-13 13:35:42","TRT02EDTM":"2022-02-13 19:35:42","AP01SDTM":"2019-08-26 05:10:30","AP01EDTM":"2021-02-13 13:35:42","AP02SDTM":"2021-02-13 13:35:42","AP02EDTM":"2022-02-13 19:35:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":903,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":923,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":42,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.44936,"AVALU":"U/L","BASE2":21.70019,"BASE":32.77299,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-20.25083,"PCHG2":-93.32098,"CHG":-31.32363,"PCHG":-95.57758,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-01-22 05:10:30","ADY":149,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-35","SUBJID":"id-35","SITEID":"NGA-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":9.02841,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-26 05:10:30","TRTEDTM":"2022-02-13 19:35:42","TRT01SDTM":"2019-08-26 05:10:30","TRT01EDTM":"2021-02-13 13:35:42","TRT02SDTM":"2021-02-13 13:35:42","TRT02EDTM":"2022-02-13 19:35:42","AP01SDTM":"2019-08-26 05:10:30","AP01EDTM":"2021-02-13 13:35:42","AP02SDTM":"2021-02-13 13:35:42","AP02EDTM":"2022-02-13 19:35:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":903,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":923,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4529,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.57091,"AVALU":"U/L","BASE2":21.70019,"BASE":32.77299,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.12928,"PCHG2":-42.07005,"CHG":-20.20208,"PCHG":-61.64247,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-27 05:10:30","ADY":428,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-35","SUBJID":"id-35","SITEID":"NGA-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":9.02841,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-26 05:10:30","TRTEDTM":"2022-02-13 19:35:42","TRT01SDTM":"2019-08-26 05:10:30","TRT01EDTM":"2021-02-13 13:35:42","TRT02SDTM":"2021-02-13 13:35:42","TRT02EDTM":"2022-02-13 19:35:42","AP01SDTM":"2019-08-26 05:10:30","AP01EDTM":"2021-02-13 13:35:42","AP02SDTM":"2021-02-13 13:35:42","AP02EDTM":"2022-02-13 19:35:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":903,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":923,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7140,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.23266,"AVALU":"U/L","BASE2":21.70019,"BASE":32.77299,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.46753,"PCHG2":-43.6288,"CHG":-20.54033,"PCHG":-62.67458,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-05 05:10:30","ADY":741,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-35","SUBJID":"id-35","SITEID":"NGA-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":9.02841,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-26 05:10:30","TRTEDTM":"2022-02-13 19:35:42","TRT01SDTM":"2019-08-26 05:10:30","TRT01EDTM":"2021-02-13 13:35:42","TRT02SDTM":"2021-02-13 13:35:42","TRT02EDTM":"2022-02-13 19:35:42","AP01SDTM":"2019-08-26 05:10:30","AP01EDTM":"2021-02-13 13:35:42","AP02SDTM":"2021-02-13 13:35:42","AP02EDTM":"2022-02-13 19:35:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":903,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":923,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3926,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.6755,"AVALU":"U/L","BASE2":21.70019,"BASE":32.77299,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.02469,"PCHG2":-46.19631,"CHG":-21.09749,"PCHG":-64.37462,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-16 05:10:30","ADY":843,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-35","SUBJID":"id-35","SITEID":"NGA-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":9.02841,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-26 05:10:30","TRTEDTM":"2022-02-13 19:35:42","TRT01SDTM":"2019-08-26 05:10:30","TRT01EDTM":"2021-02-13 13:35:42","TRT02SDTM":"2021-02-13 13:35:42","TRT02EDTM":"2022-02-13 19:35:42","AP01SDTM":"2019-08-26 05:10:30","AP01EDTM":"2021-02-13 13:35:42","AP02SDTM":"2021-02-13 13:35:42","AP02EDTM":"2022-02-13 19:35:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":903,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":923,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4128,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.09979,"AVALU":"U/L","BASE2":21.70019,"BASE":32.77299,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.6004,"PCHG2":-30.41633,"CHG":-17.6732,"PCHG":-53.92612,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-25 05:10:30","ADY":852,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-35","SUBJID":"id-35","SITEID":"NGA-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":9.02841,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-26 05:10:30","TRTEDTM":"2022-02-13 19:35:42","TRT01SDTM":"2019-08-26 05:10:30","TRT01EDTM":"2021-02-13 13:35:42","TRT02SDTM":"2021-02-13 13:35:42","TRT02EDTM":"2022-02-13 19:35:42","AP01SDTM":"2019-08-26 05:10:30","AP01EDTM":"2021-02-13 13:35:42","AP02SDTM":"2021-02-13 13:35:42","AP02EDTM":"2022-02-13 19:35:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":903,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":923,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5196,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.95251,"AVALU":"mg/L","BASE2":8.95251,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-02 05:10:30","ADY":37,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-35","SUBJID":"id-35","SITEID":"NGA-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":9.02841,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-26 05:10:30","TRTEDTM":"2022-02-13 19:35:42","TRT01SDTM":"2019-08-26 05:10:30","TRT01EDTM":"2021-02-13 13:35:42","TRT02SDTM":"2021-02-13 13:35:42","TRT02EDTM":"2022-02-13 19:35:42","AP01SDTM":"2019-08-26 05:10:30","AP01EDTM":"2021-02-13 13:35:42","AP02SDTM":"2021-02-13 13:35:42","AP02EDTM":"2022-02-13 19:35:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":903,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":923,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4334,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.78538,"AVALU":"mg/L","BASE2":8.95251,"BASE":8.78538,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.16713,"PCHG2":-1.86686,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-16 05:10:30","ADY":143,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-35","SUBJID":"id-35","SITEID":"NGA-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":9.02841,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-26 05:10:30","TRTEDTM":"2022-02-13 19:35:42","TRT01SDTM":"2019-08-26 05:10:30","TRT01EDTM":"2021-02-13 13:35:42","TRT02SDTM":"2021-02-13 13:35:42","TRT02EDTM":"2022-02-13 19:35:42","AP01SDTM":"2019-08-26 05:10:30","AP01EDTM":"2021-02-13 13:35:42","AP02SDTM":"2021-02-13 13:35:42","AP02EDTM":"2022-02-13 19:35:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":903,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":923,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1144,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.20512,"AVALU":"mg/L","BASE2":8.95251,"BASE":8.78538,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.25261,"PCHG2":25.16181,"CHG":2.41974,"PCHG":27.54286,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-01-22 05:10:30","ADY":149,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-35","SUBJID":"id-35","SITEID":"NGA-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":9.02841,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-26 05:10:30","TRTEDTM":"2022-02-13 19:35:42","TRT01SDTM":"2019-08-26 05:10:30","TRT01EDTM":"2021-02-13 13:35:42","TRT02SDTM":"2021-02-13 13:35:42","TRT02EDTM":"2022-02-13 19:35:42","AP01SDTM":"2019-08-26 05:10:30","AP01EDTM":"2021-02-13 13:35:42","AP02SDTM":"2021-02-13 13:35:42","AP02EDTM":"2022-02-13 19:35:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":903,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":923,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5747,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.51148,"AVALU":"mg/L","BASE2":8.95251,"BASE":8.78538,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.44103,"PCHG2":-4.92628,"CHG":-0.27389,"PCHG":-3.11762,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-27 05:10:30","ADY":428,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-35","SUBJID":"id-35","SITEID":"NGA-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":9.02841,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-26 05:10:30","TRTEDTM":"2022-02-13 19:35:42","TRT01SDTM":"2019-08-26 05:10:30","TRT01EDTM":"2021-02-13 13:35:42","TRT02SDTM":"2021-02-13 13:35:42","TRT02EDTM":"2022-02-13 19:35:42","AP01SDTM":"2019-08-26 05:10:30","AP01EDTM":"2021-02-13 13:35:42","AP02SDTM":"2021-02-13 13:35:42","AP02EDTM":"2022-02-13 19:35:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":903,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":923,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5756,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.19891,"AVALU":"mg/L","BASE2":8.95251,"BASE":8.78538,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.2464,"PCHG2":2.75233,"CHG":0.41353,"PCHG":4.70707,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-05 05:10:30","ADY":741,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-35","SUBJID":"id-35","SITEID":"NGA-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":9.02841,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-26 05:10:30","TRTEDTM":"2022-02-13 19:35:42","TRT01SDTM":"2019-08-26 05:10:30","TRT01EDTM":"2021-02-13 13:35:42","TRT02SDTM":"2021-02-13 13:35:42","TRT02EDTM":"2022-02-13 19:35:42","AP01SDTM":"2019-08-26 05:10:30","AP01EDTM":"2021-02-13 13:35:42","AP02SDTM":"2021-02-13 13:35:42","AP02EDTM":"2022-02-13 19:35:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":903,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":923,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6425,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.84505,"AVALU":"mg/L","BASE2":8.95251,"BASE":8.78538,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10746,"PCHG2":-1.20033,"CHG":0.05967,"PCHG":0.67921,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-16 05:10:30","ADY":843,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-35","SUBJID":"id-35","SITEID":"NGA-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":9.02841,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-26 05:10:30","TRTEDTM":"2022-02-13 19:35:42","TRT01SDTM":"2019-08-26 05:10:30","TRT01EDTM":"2021-02-13 13:35:42","TRT02SDTM":"2021-02-13 13:35:42","TRT02EDTM":"2022-02-13 19:35:42","AP01SDTM":"2019-08-26 05:10:30","AP01EDTM":"2021-02-13 13:35:42","AP02SDTM":"2021-02-13 13:35:42","AP02EDTM":"2022-02-13 19:35:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":903,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":923,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4265,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.94727,"AVALU":"mg/L","BASE2":8.95251,"BASE":8.78538,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00524,"PCHG2":-0.05851,"CHG":0.16189,"PCHG":1.84275,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-25 05:10:30","ADY":852,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-35","SUBJID":"id-35","SITEID":"NGA-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":9.02841,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-26 05:10:30","TRTEDTM":"2022-02-13 19:35:42","TRT01SDTM":"2019-08-26 05:10:30","TRT01EDTM":"2021-02-13 13:35:42","TRT02SDTM":"2021-02-13 13:35:42","TRT02EDTM":"2022-02-13 19:35:42","AP01SDTM":"2019-08-26 05:10:30","AP01EDTM":"2021-02-13 13:35:42","AP02SDTM":"2021-02-13 13:35:42","AP02EDTM":"2022-02-13 19:35:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":903,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":923,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7124,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03244,"AVALU":"g/L","BASE2":3.03244,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2019-10-02 05:10:30","ADY":37,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-35","SUBJID":"id-35","SITEID":"NGA-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":9.02841,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-26 05:10:30","TRTEDTM":"2022-02-13 19:35:42","TRT01SDTM":"2019-08-26 05:10:30","TRT01EDTM":"2021-02-13 13:35:42","TRT02SDTM":"2021-02-13 13:35:42","TRT02EDTM":"2022-02-13 19:35:42","AP01SDTM":"2019-08-26 05:10:30","AP01EDTM":"2021-02-13 13:35:42","AP02SDTM":"2021-02-13 13:35:42","AP02EDTM":"2022-02-13 19:35:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":903,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":923,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4519,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81018,"AVALU":"g/L","BASE2":3.03244,"BASE":2.81018,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.22226,"PCHG2":-7.32948,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-16 05:10:30","ADY":143,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-35","SUBJID":"id-35","SITEID":"NGA-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":9.02841,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-26 05:10:30","TRTEDTM":"2022-02-13 19:35:42","TRT01SDTM":"2019-08-26 05:10:30","TRT01EDTM":"2021-02-13 13:35:42","TRT02SDTM":"2021-02-13 13:35:42","TRT02EDTM":"2022-02-13 19:35:42","AP01SDTM":"2019-08-26 05:10:30","AP01EDTM":"2021-02-13 13:35:42","AP02SDTM":"2021-02-13 13:35:42","AP02EDTM":"2022-02-13 19:35:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":903,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":923,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6640,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92308,"AVALU":"g/L","BASE2":3.03244,"BASE":2.81018,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10936,"PCHG2":-3.60641,"CHG":0.1129,"PCHG":4.01754,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-22 05:10:30","ADY":149,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-35","SUBJID":"id-35","SITEID":"NGA-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":9.02841,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-26 05:10:30","TRTEDTM":"2022-02-13 19:35:42","TRT01SDTM":"2019-08-26 05:10:30","TRT01EDTM":"2021-02-13 13:35:42","TRT02SDTM":"2021-02-13 13:35:42","TRT02EDTM":"2022-02-13 19:35:42","AP01SDTM":"2019-08-26 05:10:30","AP01EDTM":"2021-02-13 13:35:42","AP02SDTM":"2021-02-13 13:35:42","AP02EDTM":"2022-02-13 19:35:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":903,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":923,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":314,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.71937,"AVALU":"g/L","BASE2":3.03244,"BASE":2.81018,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.31307,"PCHG2":-10.32407,"CHG":-0.09081,"PCHG":-3.23143,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-27 05:10:30","ADY":428,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-35","SUBJID":"id-35","SITEID":"NGA-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":9.02841,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-26 05:10:30","TRTEDTM":"2022-02-13 19:35:42","TRT01SDTM":"2019-08-26 05:10:30","TRT01EDTM":"2021-02-13 13:35:42","TRT02SDTM":"2021-02-13 13:35:42","TRT02EDTM":"2022-02-13 19:35:42","AP01SDTM":"2019-08-26 05:10:30","AP01EDTM":"2021-02-13 13:35:42","AP02SDTM":"2021-02-13 13:35:42","AP02EDTM":"2022-02-13 19:35:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":903,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":923,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8105,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03782,"AVALU":"g/L","BASE2":3.03244,"BASE":2.81018,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00538,"PCHG2":0.17738,"CHG":0.22764,"PCHG":8.1006,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-09-05 05:10:30","ADY":741,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-35","SUBJID":"id-35","SITEID":"NGA-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":9.02841,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-26 05:10:30","TRTEDTM":"2022-02-13 19:35:42","TRT01SDTM":"2019-08-26 05:10:30","TRT01EDTM":"2021-02-13 13:35:42","TRT02SDTM":"2021-02-13 13:35:42","TRT02EDTM":"2022-02-13 19:35:42","AP01SDTM":"2019-08-26 05:10:30","AP01EDTM":"2021-02-13 13:35:42","AP02SDTM":"2021-02-13 13:35:42","AP02EDTM":"2022-02-13 19:35:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":903,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":923,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7219,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79063,"AVALU":"g/L","BASE2":3.03244,"BASE":2.81018,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.24181,"PCHG2":-7.97404,"CHG":-0.01955,"PCHG":-0.69553,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-16 05:10:30","ADY":843,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-35","SUBJID":"id-35","SITEID":"NGA-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":9.02841,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-24","TRTSDTM":"2019-08-26 05:10:30","TRTEDTM":"2022-02-13 19:35:42","TRT01SDTM":"2019-08-26 05:10:30","TRT01EDTM":"2021-02-13 13:35:42","TRT02SDTM":"2021-02-13 13:35:42","TRT02EDTM":"2022-02-13 19:35:42","AP01SDTM":"2019-08-26 05:10:30","AP01EDTM":"2021-02-13 13:35:42","AP02SDTM":"2021-02-13 13:35:42","AP02EDTM":"2022-02-13 19:35:42","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":903,"DCSREAS":"DEATH","DTHDT":"2022-03-07","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-07","DTHADY":923,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6724,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85897,"AVALU":"g/L","BASE2":3.03244,"BASE":2.81018,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17348,"PCHG2":-5.72068,"CHG":0.04879,"PCHG":1.73605,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-25 05:10:30","ADY":852,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-366","SUBJID":"id-366","SITEID":"NGA-11","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":3.31624,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-04","TRTSDTM":"2020-10-05 21:21:07","TRTEDTM":"2023-10-06 15:21:07","TRT01SDTM":"2020-10-05 21:21:07","TRT01EDTM":"2022-10-06 09:21:07","TRT02SDTM":"2022-10-06 09:21:07","TRT02EDTM":"2023-10-06 15:21:07","AP01SDTM":"2020-10-05 21:21:07","AP01EDTM":"2022-10-06 09:21:07","AP02SDTM":"2022-10-06 09:21:07","AP02EDTM":"2023-10-06 15:21:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-06","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2717,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.466,"AVALU":"U/L","BASE2":14.466,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-18 21:21:07","ADY":105,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-366","SUBJID":"id-366","SITEID":"NGA-11","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":3.31624,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-04","TRTSDTM":"2020-10-05 21:21:07","TRTEDTM":"2023-10-06 15:21:07","TRT01SDTM":"2020-10-05 21:21:07","TRT01EDTM":"2022-10-06 09:21:07","TRT02SDTM":"2022-10-06 09:21:07","TRT02EDTM":"2023-10-06 15:21:07","AP01SDTM":"2020-10-05 21:21:07","AP01EDTM":"2022-10-06 09:21:07","AP02SDTM":"2022-10-06 09:21:07","AP02EDTM":"2023-10-06 15:21:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-06","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6507,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.91724,"AVALU":"U/L","BASE2":14.466,"BASE":18.91724,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":4.45124,"PCHG2":30.77039,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-10 21:21:07","ADY":309,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-366","SUBJID":"id-366","SITEID":"NGA-11","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":3.31624,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-04","TRTSDTM":"2020-10-05 21:21:07","TRTEDTM":"2023-10-06 15:21:07","TRT01SDTM":"2020-10-05 21:21:07","TRT01EDTM":"2022-10-06 09:21:07","TRT02SDTM":"2022-10-06 09:21:07","TRT02EDTM":"2023-10-06 15:21:07","AP01SDTM":"2020-10-05 21:21:07","AP01EDTM":"2022-10-06 09:21:07","AP02SDTM":"2022-10-06 09:21:07","AP02EDTM":"2023-10-06 15:21:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-06","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4699,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.42,"AVALU":"U/L","BASE2":14.466,"BASE":18.91724,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.954,"PCHG2":13.50753,"CHG":-2.49724,"PCHG":-13.20089,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-25 21:21:07","ADY":324,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-366","SUBJID":"id-366","SITEID":"NGA-11","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":3.31624,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-04","TRTSDTM":"2020-10-05 21:21:07","TRTEDTM":"2023-10-06 15:21:07","TRT01SDTM":"2020-10-05 21:21:07","TRT01EDTM":"2022-10-06 09:21:07","TRT02SDTM":"2022-10-06 09:21:07","TRT02EDTM":"2023-10-06 15:21:07","AP01SDTM":"2020-10-05 21:21:07","AP01EDTM":"2022-10-06 09:21:07","AP02SDTM":"2022-10-06 09:21:07","AP02EDTM":"2023-10-06 15:21:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-06","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7837,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":41.44623,"AVALU":"U/L","BASE2":14.466,"BASE":18.91724,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":26.98024,"PCHG2":186.50797,"CHG":22.52899,"PCHG":119.09239,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-01 21:21:07","ADY":573,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-366","SUBJID":"id-366","SITEID":"NGA-11","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":3.31624,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-04","TRTSDTM":"2020-10-05 21:21:07","TRTEDTM":"2023-10-06 15:21:07","TRT01SDTM":"2020-10-05 21:21:07","TRT01EDTM":"2022-10-06 09:21:07","TRT02SDTM":"2022-10-06 09:21:07","TRT02EDTM":"2023-10-06 15:21:07","AP01SDTM":"2020-10-05 21:21:07","AP01EDTM":"2022-10-06 09:21:07","AP02SDTM":"2022-10-06 09:21:07","AP02EDTM":"2023-10-06 15:21:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-06","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6943,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.263,"AVALU":"U/L","BASE2":14.466,"BASE":18.91724,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.797,"PCHG2":102.28813,"CHG":10.34576,"PCHG":54.68956,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-03 21:21:07","ADY":575,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-366","SUBJID":"id-366","SITEID":"NGA-11","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":3.31624,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-04","TRTSDTM":"2020-10-05 21:21:07","TRTEDTM":"2023-10-06 15:21:07","TRT01SDTM":"2020-10-05 21:21:07","TRT01EDTM":"2022-10-06 09:21:07","TRT02SDTM":"2022-10-06 09:21:07","TRT02EDTM":"2023-10-06 15:21:07","AP01SDTM":"2020-10-05 21:21:07","AP01EDTM":"2022-10-06 09:21:07","AP02SDTM":"2022-10-06 09:21:07","AP02EDTM":"2023-10-06 15:21:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-06","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4373,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.71545,"AVALU":"U/L","BASE2":14.466,"BASE":18.91724,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":17.24946,"PCHG2":119.24139,"CHG":12.79821,"PCHG":67.6537,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-22 21:21:07","ADY":594,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-366","SUBJID":"id-366","SITEID":"NGA-11","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":3.31624,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-04","TRTSDTM":"2020-10-05 21:21:07","TRTEDTM":"2023-10-06 15:21:07","TRT01SDTM":"2020-10-05 21:21:07","TRT01EDTM":"2022-10-06 09:21:07","TRT02SDTM":"2022-10-06 09:21:07","TRT02EDTM":"2023-10-06 15:21:07","AP01SDTM":"2020-10-05 21:21:07","AP01EDTM":"2022-10-06 09:21:07","AP02SDTM":"2022-10-06 09:21:07","AP02EDTM":"2023-10-06 15:21:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-06","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8185,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.2683,"AVALU":"U/L","BASE2":14.466,"BASE":18.91724,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.1977,"PCHG2":-63.5815,"CHG":-13.64894,"PCHG":-72.1508,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2023-08-03 21:21:07","ADY":1032,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-366","SUBJID":"id-366","SITEID":"NGA-11","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":3.31624,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-04","TRTSDTM":"2020-10-05 21:21:07","TRTEDTM":"2023-10-06 15:21:07","TRT01SDTM":"2020-10-05 21:21:07","TRT01EDTM":"2022-10-06 09:21:07","TRT02SDTM":"2022-10-06 09:21:07","TRT02EDTM":"2023-10-06 15:21:07","AP01SDTM":"2020-10-05 21:21:07","AP01EDTM":"2022-10-06 09:21:07","AP02SDTM":"2022-10-06 09:21:07","AP02EDTM":"2023-10-06 15:21:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-06","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4853,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.02916,"AVALU":"mg/L","BASE2":8.02916,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-18 21:21:07","ADY":105,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-366","SUBJID":"id-366","SITEID":"NGA-11","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":3.31624,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-04","TRTSDTM":"2020-10-05 21:21:07","TRTEDTM":"2023-10-06 15:21:07","TRT01SDTM":"2020-10-05 21:21:07","TRT01EDTM":"2022-10-06 09:21:07","TRT02SDTM":"2022-10-06 09:21:07","TRT02EDTM":"2023-10-06 15:21:07","AP01SDTM":"2020-10-05 21:21:07","AP01EDTM":"2022-10-06 09:21:07","AP02SDTM":"2022-10-06 09:21:07","AP02EDTM":"2023-10-06 15:21:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-06","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5839,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.42029,"AVALU":"mg/L","BASE2":8.02916,"BASE":8.42029,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.39112,"PCHG2":4.87129,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-10 21:21:07","ADY":309,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-366","SUBJID":"id-366","SITEID":"NGA-11","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":3.31624,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-04","TRTSDTM":"2020-10-05 21:21:07","TRTEDTM":"2023-10-06 15:21:07","TRT01SDTM":"2020-10-05 21:21:07","TRT01EDTM":"2022-10-06 09:21:07","TRT02SDTM":"2022-10-06 09:21:07","TRT02EDTM":"2023-10-06 15:21:07","AP01SDTM":"2020-10-05 21:21:07","AP01EDTM":"2022-10-06 09:21:07","AP02SDTM":"2022-10-06 09:21:07","AP02EDTM":"2023-10-06 15:21:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-06","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4965,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.09342,"AVALU":"mg/L","BASE2":8.02916,"BASE":8.42029,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06425,"PCHG2":0.80024,"CHG":-0.32687,"PCHG":-3.88195,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-25 21:21:07","ADY":324,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-366","SUBJID":"id-366","SITEID":"NGA-11","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":3.31624,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-04","TRTSDTM":"2020-10-05 21:21:07","TRTEDTM":"2023-10-06 15:21:07","TRT01SDTM":"2020-10-05 21:21:07","TRT01EDTM":"2022-10-06 09:21:07","TRT02SDTM":"2022-10-06 09:21:07","TRT02EDTM":"2023-10-06 15:21:07","AP01SDTM":"2020-10-05 21:21:07","AP01EDTM":"2022-10-06 09:21:07","AP02SDTM":"2022-10-06 09:21:07","AP02EDTM":"2023-10-06 15:21:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-06","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1137,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.01759,"AVALU":"mg/L","BASE2":8.02916,"BASE":8.42029,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.98842,"PCHG2":12.31041,"CHG":0.5973,"PCHG":7.09358,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-01 21:21:07","ADY":573,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-366","SUBJID":"id-366","SITEID":"NGA-11","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":3.31624,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-04","TRTSDTM":"2020-10-05 21:21:07","TRTEDTM":"2023-10-06 15:21:07","TRT01SDTM":"2020-10-05 21:21:07","TRT01EDTM":"2022-10-06 09:21:07","TRT02SDTM":"2022-10-06 09:21:07","TRT02EDTM":"2023-10-06 15:21:07","AP01SDTM":"2020-10-05 21:21:07","AP01EDTM":"2022-10-06 09:21:07","AP02SDTM":"2022-10-06 09:21:07","AP02EDTM":"2023-10-06 15:21:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-06","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3959,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.55972,"AVALU":"mg/L","BASE2":8.02916,"BASE":8.42029,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.53056,"PCHG2":6.60786,"CHG":0.13943,"PCHG":1.65591,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-03 21:21:07","ADY":575,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-366","SUBJID":"id-366","SITEID":"NGA-11","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":3.31624,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-04","TRTSDTM":"2020-10-05 21:21:07","TRTEDTM":"2023-10-06 15:21:07","TRT01SDTM":"2020-10-05 21:21:07","TRT01EDTM":"2022-10-06 09:21:07","TRT02SDTM":"2022-10-06 09:21:07","TRT02EDTM":"2023-10-06 15:21:07","AP01SDTM":"2020-10-05 21:21:07","AP01EDTM":"2022-10-06 09:21:07","AP02SDTM":"2022-10-06 09:21:07","AP02EDTM":"2023-10-06 15:21:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-06","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8100,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.61251,"AVALU":"mg/L","BASE2":8.02916,"BASE":8.42029,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.58334,"PCHG2":7.2653,"CHG":0.19222,"PCHG":2.28282,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-22 21:21:07","ADY":594,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-366","SUBJID":"id-366","SITEID":"NGA-11","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":3.31624,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-04","TRTSDTM":"2020-10-05 21:21:07","TRTEDTM":"2023-10-06 15:21:07","TRT01SDTM":"2020-10-05 21:21:07","TRT01EDTM":"2022-10-06 09:21:07","TRT02SDTM":"2022-10-06 09:21:07","TRT02EDTM":"2023-10-06 15:21:07","AP01SDTM":"2020-10-05 21:21:07","AP01EDTM":"2022-10-06 09:21:07","AP02SDTM":"2022-10-06 09:21:07","AP02EDTM":"2023-10-06 15:21:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-06","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1703,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.62943,"AVALU":"mg/L","BASE2":8.02916,"BASE":8.42029,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.60027,"PCHG2":19.93068,"CHG":1.20914,"PCHG":14.35988,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-03 21:21:07","ADY":1032,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-366","SUBJID":"id-366","SITEID":"NGA-11","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":3.31624,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-04","TRTSDTM":"2020-10-05 21:21:07","TRTEDTM":"2023-10-06 15:21:07","TRT01SDTM":"2020-10-05 21:21:07","TRT01EDTM":"2022-10-06 09:21:07","TRT02SDTM":"2022-10-06 09:21:07","TRT02EDTM":"2023-10-06 15:21:07","AP01SDTM":"2020-10-05 21:21:07","AP01EDTM":"2022-10-06 09:21:07","AP02SDTM":"2022-10-06 09:21:07","AP02EDTM":"2023-10-06 15:21:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-06","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6694,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8001,"AVALU":"g/L","BASE2":2.8001,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-18 21:21:07","ADY":105,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-366","SUBJID":"id-366","SITEID":"NGA-11","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":3.31624,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-04","TRTSDTM":"2020-10-05 21:21:07","TRTEDTM":"2023-10-06 15:21:07","TRT01SDTM":"2020-10-05 21:21:07","TRT01EDTM":"2022-10-06 09:21:07","TRT02SDTM":"2022-10-06 09:21:07","TRT02EDTM":"2023-10-06 15:21:07","AP01SDTM":"2020-10-05 21:21:07","AP01EDTM":"2022-10-06 09:21:07","AP02SDTM":"2022-10-06 09:21:07","AP02EDTM":"2023-10-06 15:21:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-06","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":406,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88525,"AVALU":"g/L","BASE2":2.8001,"BASE":2.88525,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.08515,"PCHG2":3.04106,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-10 21:21:07","ADY":309,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-366","SUBJID":"id-366","SITEID":"NGA-11","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":3.31624,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-04","TRTSDTM":"2020-10-05 21:21:07","TRTEDTM":"2023-10-06 15:21:07","TRT01SDTM":"2020-10-05 21:21:07","TRT01EDTM":"2022-10-06 09:21:07","TRT02SDTM":"2022-10-06 09:21:07","TRT02EDTM":"2023-10-06 15:21:07","AP01SDTM":"2020-10-05 21:21:07","AP01EDTM":"2022-10-06 09:21:07","AP02SDTM":"2022-10-06 09:21:07","AP02EDTM":"2023-10-06 15:21:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-06","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6495,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85881,"AVALU":"g/L","BASE2":2.8001,"BASE":2.88525,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05871,"PCHG2":2.09666,"CHG":-0.02644,"PCHG":-0.91652,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-25 21:21:07","ADY":324,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-366","SUBJID":"id-366","SITEID":"NGA-11","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":3.31624,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-04","TRTSDTM":"2020-10-05 21:21:07","TRTEDTM":"2023-10-06 15:21:07","TRT01SDTM":"2020-10-05 21:21:07","TRT01EDTM":"2022-10-06 09:21:07","TRT02SDTM":"2022-10-06 09:21:07","TRT02EDTM":"2023-10-06 15:21:07","AP01SDTM":"2020-10-05 21:21:07","AP01EDTM":"2022-10-06 09:21:07","AP02SDTM":"2022-10-06 09:21:07","AP02EDTM":"2023-10-06 15:21:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-06","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3231,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75257,"AVALU":"g/L","BASE2":2.8001,"BASE":2.88525,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04753,"PCHG2":-1.69741,"CHG":-0.13268,"PCHG":-4.59862,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-01 21:21:07","ADY":573,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-366","SUBJID":"id-366","SITEID":"NGA-11","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":3.31624,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-04","TRTSDTM":"2020-10-05 21:21:07","TRTEDTM":"2023-10-06 15:21:07","TRT01SDTM":"2020-10-05 21:21:07","TRT01EDTM":"2022-10-06 09:21:07","TRT02SDTM":"2022-10-06 09:21:07","TRT02EDTM":"2023-10-06 15:21:07","AP01SDTM":"2020-10-05 21:21:07","AP01EDTM":"2022-10-06 09:21:07","AP02SDTM":"2022-10-06 09:21:07","AP02EDTM":"2023-10-06 15:21:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-06","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8188,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96946,"AVALU":"g/L","BASE2":2.8001,"BASE":2.88525,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16936,"PCHG2":6.04825,"CHG":0.0842,"PCHG":2.91844,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-03 21:21:07","ADY":575,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-366","SUBJID":"id-366","SITEID":"NGA-11","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":3.31624,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-04","TRTSDTM":"2020-10-05 21:21:07","TRTEDTM":"2023-10-06 15:21:07","TRT01SDTM":"2020-10-05 21:21:07","TRT01EDTM":"2022-10-06 09:21:07","TRT02SDTM":"2022-10-06 09:21:07","TRT02EDTM":"2023-10-06 15:21:07","AP01SDTM":"2020-10-05 21:21:07","AP01EDTM":"2022-10-06 09:21:07","AP02SDTM":"2022-10-06 09:21:07","AP02EDTM":"2023-10-06 15:21:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-06","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5321,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90036,"AVALU":"g/L","BASE2":2.8001,"BASE":2.88525,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10026,"PCHG2":3.58071,"CHG":0.01511,"PCHG":0.52372,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-22 21:21:07","ADY":594,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-366","SUBJID":"id-366","SITEID":"NGA-11","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":3.31624,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-10-04","TRTSDTM":"2020-10-05 21:21:07","TRTEDTM":"2023-10-06 15:21:07","TRT01SDTM":"2020-10-05 21:21:07","TRT01EDTM":"2022-10-06 09:21:07","TRT02SDTM":"2022-10-06 09:21:07","TRT02EDTM":"2023-10-06 15:21:07","AP01SDTM":"2020-10-05 21:21:07","AP01EDTM":"2022-10-06 09:21:07","AP02SDTM":"2022-10-06 09:21:07","AP02EDTM":"2023-10-06 15:21:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-06","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3568,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95205,"AVALU":"g/L","BASE2":2.8001,"BASE":2.88525,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15195,"PCHG2":5.42647,"CHG":0.06679,"PCHG":2.31501,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-03 21:21:07","ADY":1032,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-41","SUBJID":"id-41","SITEID":"NGA-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":7.20651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-08-01 00:52:12","TRTEDTM":"2023-08-01 18:52:12","TRT01SDTM":"2020-08-01 00:52:12","TRT01EDTM":"2022-08-01 12:52:12","TRT02SDTM":"2022-08-01 12:52:12","TRT02EDTM":"2023-08-01 18:52:12","AP01SDTM":"2020-08-01 00:52:12","AP01EDTM":"2022-08-01 12:52:12","AP02SDTM":"2022-08-01 12:52:12","AP02EDTM":"2023-08-01 18:52:12","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-19","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6491,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.05159,"AVALU":"U/L","BASE2":28.05159,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-02 00:52:12","ADY":62,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-41","SUBJID":"id-41","SITEID":"NGA-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":7.20651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-08-01 00:52:12","TRTEDTM":"2023-08-01 18:52:12","TRT01SDTM":"2020-08-01 00:52:12","TRT01EDTM":"2022-08-01 12:52:12","TRT02SDTM":"2022-08-01 12:52:12","TRT02EDTM":"2023-08-01 18:52:12","AP01SDTM":"2020-08-01 00:52:12","AP01EDTM":"2022-08-01 12:52:12","AP02SDTM":"2022-08-01 12:52:12","AP02EDTM":"2023-08-01 18:52:12","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-19","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3807,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.4935,"AVALU":"U/L","BASE2":28.05159,"BASE":22.4935,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-5.55809,"PCHG2":-19.81382,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-19 00:52:12","ADY":171,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-41","SUBJID":"id-41","SITEID":"NGA-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":7.20651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-08-01 00:52:12","TRTEDTM":"2023-08-01 18:52:12","TRT01SDTM":"2020-08-01 00:52:12","TRT01EDTM":"2022-08-01 12:52:12","TRT02SDTM":"2022-08-01 12:52:12","TRT02EDTM":"2023-08-01 18:52:12","AP01SDTM":"2020-08-01 00:52:12","AP01EDTM":"2022-08-01 12:52:12","AP02SDTM":"2022-08-01 12:52:12","AP02EDTM":"2023-08-01 18:52:12","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-19","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5075,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.61711,"AVALU":"U/L","BASE2":28.05159,"BASE":22.4935,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.43448,"PCHG2":-37.19748,"CHG":-4.87639,"PCHG":-21.67912,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-22 00:52:12","ADY":174,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-41","SUBJID":"id-41","SITEID":"NGA-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":7.20651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-08-01 00:52:12","TRTEDTM":"2023-08-01 18:52:12","TRT01SDTM":"2020-08-01 00:52:12","TRT01EDTM":"2022-08-01 12:52:12","TRT02SDTM":"2022-08-01 12:52:12","TRT02EDTM":"2023-08-01 18:52:12","AP01SDTM":"2020-08-01 00:52:12","AP01EDTM":"2022-08-01 12:52:12","AP02SDTM":"2022-08-01 12:52:12","AP02EDTM":"2023-08-01 18:52:12","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-19","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6325,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.90087,"AVALU":"U/L","BASE2":28.05159,"BASE":22.4935,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.15072,"PCHG2":-18.3616,"CHG":0.40737,"PCHG":1.81106,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-20 00:52:12","ADY":384,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-41","SUBJID":"id-41","SITEID":"NGA-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":7.20651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-08-01 00:52:12","TRTEDTM":"2023-08-01 18:52:12","TRT01SDTM":"2020-08-01 00:52:12","TRT01EDTM":"2022-08-01 12:52:12","TRT02SDTM":"2022-08-01 12:52:12","TRT02EDTM":"2023-08-01 18:52:12","AP01SDTM":"2020-08-01 00:52:12","AP01EDTM":"2022-08-01 12:52:12","AP02SDTM":"2022-08-01 12:52:12","AP02EDTM":"2023-08-01 18:52:12","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-19","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7381,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.4146,"AVALU":"U/L","BASE2":28.05159,"BASE":22.4935,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-19.63699,"PCHG2":-70.00314,"CHG":-14.0789,"PCHG":-62.59098,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-04 00:52:12","ADY":611,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-41","SUBJID":"id-41","SITEID":"NGA-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":7.20651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-08-01 00:52:12","TRTEDTM":"2023-08-01 18:52:12","TRT01SDTM":"2020-08-01 00:52:12","TRT01EDTM":"2022-08-01 12:52:12","TRT02SDTM":"2022-08-01 12:52:12","TRT02EDTM":"2023-08-01 18:52:12","AP01SDTM":"2020-08-01 00:52:12","AP01EDTM":"2022-08-01 12:52:12","AP02SDTM":"2022-08-01 12:52:12","AP02EDTM":"2023-08-01 18:52:12","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-19","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8017,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.96919,"AVALU":"U/L","BASE2":28.05159,"BASE":22.4935,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.9176,"PCHG2":3.27112,"CHG":6.47569,"PCHG":28.78917,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-16 00:52:12","ADY":714,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-41","SUBJID":"id-41","SITEID":"NGA-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":7.20651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-08-01 00:52:12","TRTEDTM":"2023-08-01 18:52:12","TRT01SDTM":"2020-08-01 00:52:12","TRT01EDTM":"2022-08-01 12:52:12","TRT02SDTM":"2022-08-01 12:52:12","TRT02EDTM":"2023-08-01 18:52:12","AP01SDTM":"2020-08-01 00:52:12","AP01EDTM":"2022-08-01 12:52:12","AP02SDTM":"2022-08-01 12:52:12","AP02EDTM":"2023-08-01 18:52:12","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-19","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1371,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.20598,"AVALU":"U/L","BASE2":28.05159,"BASE":22.4935,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.84561,"PCHG2":-42.22796,"CHG":-6.28752,"PCHG":-27.95262,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-20 00:52:12","ADY":992,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-41","SUBJID":"id-41","SITEID":"NGA-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":7.20651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-08-01 00:52:12","TRTEDTM":"2023-08-01 18:52:12","TRT01SDTM":"2020-08-01 00:52:12","TRT01EDTM":"2022-08-01 12:52:12","TRT02SDTM":"2022-08-01 12:52:12","TRT02EDTM":"2023-08-01 18:52:12","AP01SDTM":"2020-08-01 00:52:12","AP01EDTM":"2022-08-01 12:52:12","AP02SDTM":"2022-08-01 12:52:12","AP02EDTM":"2023-08-01 18:52:12","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-19","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1272,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.45009,"AVALU":"mg/L","BASE2":9.45009,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-02 00:52:12","ADY":62,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-41","SUBJID":"id-41","SITEID":"NGA-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":7.20651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-08-01 00:52:12","TRTEDTM":"2023-08-01 18:52:12","TRT01SDTM":"2020-08-01 00:52:12","TRT01EDTM":"2022-08-01 12:52:12","TRT02SDTM":"2022-08-01 12:52:12","TRT02EDTM":"2023-08-01 18:52:12","AP01SDTM":"2020-08-01 00:52:12","AP01EDTM":"2022-08-01 12:52:12","AP02SDTM":"2022-08-01 12:52:12","AP02EDTM":"2023-08-01 18:52:12","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-19","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8086,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.66792,"AVALU":"mg/L","BASE2":9.45009,"BASE":9.66792,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.21783,"PCHG2":2.30511,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-19 00:52:12","ADY":171,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-41","SUBJID":"id-41","SITEID":"NGA-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":7.20651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-08-01 00:52:12","TRTEDTM":"2023-08-01 18:52:12","TRT01SDTM":"2020-08-01 00:52:12","TRT01EDTM":"2022-08-01 12:52:12","TRT02SDTM":"2022-08-01 12:52:12","TRT02EDTM":"2023-08-01 18:52:12","AP01SDTM":"2020-08-01 00:52:12","AP01EDTM":"2022-08-01 12:52:12","AP02SDTM":"2022-08-01 12:52:12","AP02EDTM":"2023-08-01 18:52:12","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-19","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8346,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.51748,"AVALU":"mg/L","BASE2":9.45009,"BASE":9.66792,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0674,"PCHG2":0.71318,"CHG":-0.15044,"PCHG":-1.55605,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-22 00:52:12","ADY":174,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-41","SUBJID":"id-41","SITEID":"NGA-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":7.20651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-08-01 00:52:12","TRTEDTM":"2023-08-01 18:52:12","TRT01SDTM":"2020-08-01 00:52:12","TRT01EDTM":"2022-08-01 12:52:12","TRT02SDTM":"2022-08-01 12:52:12","TRT02EDTM":"2023-08-01 18:52:12","AP01SDTM":"2020-08-01 00:52:12","AP01EDTM":"2022-08-01 12:52:12","AP02SDTM":"2022-08-01 12:52:12","AP02EDTM":"2023-08-01 18:52:12","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-19","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4525,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.4614,"AVALU":"mg/L","BASE2":9.45009,"BASE":9.66792,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01131,"PCHG2":0.11972,"CHG":-0.20652,"PCHG":-2.13615,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-20 00:52:12","ADY":384,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-41","SUBJID":"id-41","SITEID":"NGA-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":7.20651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-08-01 00:52:12","TRTEDTM":"2023-08-01 18:52:12","TRT01SDTM":"2020-08-01 00:52:12","TRT01EDTM":"2022-08-01 12:52:12","TRT02SDTM":"2022-08-01 12:52:12","TRT02EDTM":"2023-08-01 18:52:12","AP01SDTM":"2020-08-01 00:52:12","AP01EDTM":"2022-08-01 12:52:12","AP02SDTM":"2022-08-01 12:52:12","AP02EDTM":"2023-08-01 18:52:12","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-19","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1352,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.23277,"AVALU":"mg/L","BASE2":9.45009,"BASE":9.66792,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.78269,"PCHG2":8.28234,"CHG":0.56485,"PCHG":5.84256,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-04-04 00:52:12","ADY":611,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-41","SUBJID":"id-41","SITEID":"NGA-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":7.20651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-08-01 00:52:12","TRTEDTM":"2023-08-01 18:52:12","TRT01SDTM":"2020-08-01 00:52:12","TRT01EDTM":"2022-08-01 12:52:12","TRT02SDTM":"2022-08-01 12:52:12","TRT02EDTM":"2023-08-01 18:52:12","AP01SDTM":"2020-08-01 00:52:12","AP01EDTM":"2022-08-01 12:52:12","AP02SDTM":"2022-08-01 12:52:12","AP02EDTM":"2023-08-01 18:52:12","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-19","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3380,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.42805,"AVALU":"mg/L","BASE2":9.45009,"BASE":9.66792,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.02204,"PCHG2":-10.81513,"CHG":-1.23987,"PCHG":-12.82462,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-16 00:52:12","ADY":714,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-41","SUBJID":"id-41","SITEID":"NGA-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":7.20651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-08-01 00:52:12","TRTEDTM":"2023-08-01 18:52:12","TRT01SDTM":"2020-08-01 00:52:12","TRT01EDTM":"2022-08-01 12:52:12","TRT02SDTM":"2022-08-01 12:52:12","TRT02EDTM":"2023-08-01 18:52:12","AP01SDTM":"2020-08-01 00:52:12","AP01EDTM":"2022-08-01 12:52:12","AP02SDTM":"2022-08-01 12:52:12","AP02EDTM":"2023-08-01 18:52:12","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-19","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4495,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.18891,"AVALU":"mg/L","BASE2":9.45009,"BASE":9.66792,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.26117,"PCHG2":-13.34561,"CHG":-1.47901,"PCHG":-15.29808,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-20 00:52:12","ADY":992,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-41","SUBJID":"id-41","SITEID":"NGA-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":7.20651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-08-01 00:52:12","TRTEDTM":"2023-08-01 18:52:12","TRT01SDTM":"2020-08-01 00:52:12","TRT01EDTM":"2022-08-01 12:52:12","TRT02SDTM":"2022-08-01 12:52:12","TRT02EDTM":"2023-08-01 18:52:12","AP01SDTM":"2020-08-01 00:52:12","AP01EDTM":"2022-08-01 12:52:12","AP02SDTM":"2022-08-01 12:52:12","AP02EDTM":"2023-08-01 18:52:12","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-19","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4964,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91832,"AVALU":"g/L","BASE2":2.91832,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-02 00:52:12","ADY":62,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-41","SUBJID":"id-41","SITEID":"NGA-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":7.20651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-08-01 00:52:12","TRTEDTM":"2023-08-01 18:52:12","TRT01SDTM":"2020-08-01 00:52:12","TRT01EDTM":"2022-08-01 12:52:12","TRT02SDTM":"2022-08-01 12:52:12","TRT02EDTM":"2023-08-01 18:52:12","AP01SDTM":"2020-08-01 00:52:12","AP01EDTM":"2022-08-01 12:52:12","AP02SDTM":"2022-08-01 12:52:12","AP02EDTM":"2023-08-01 18:52:12","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-19","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5897,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79199,"AVALU":"g/L","BASE2":2.91832,"BASE":2.79199,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.12633,"PCHG2":-4.32889,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-19 00:52:12","ADY":171,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-41","SUBJID":"id-41","SITEID":"NGA-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":7.20651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-08-01 00:52:12","TRTEDTM":"2023-08-01 18:52:12","TRT01SDTM":"2020-08-01 00:52:12","TRT01EDTM":"2022-08-01 12:52:12","TRT02SDTM":"2022-08-01 12:52:12","TRT02EDTM":"2023-08-01 18:52:12","AP01SDTM":"2020-08-01 00:52:12","AP01EDTM":"2022-08-01 12:52:12","AP02SDTM":"2022-08-01 12:52:12","AP02EDTM":"2023-08-01 18:52:12","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-19","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4014,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91154,"AVALU":"g/L","BASE2":2.91832,"BASE":2.79199,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00678,"PCHG2":-0.23218,"CHG":0.11955,"PCHG":4.28207,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-22 00:52:12","ADY":174,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-41","SUBJID":"id-41","SITEID":"NGA-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":7.20651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-08-01 00:52:12","TRTEDTM":"2023-08-01 18:52:12","TRT01SDTM":"2020-08-01 00:52:12","TRT01EDTM":"2022-08-01 12:52:12","TRT02SDTM":"2022-08-01 12:52:12","TRT02EDTM":"2023-08-01 18:52:12","AP01SDTM":"2020-08-01 00:52:12","AP01EDTM":"2022-08-01 12:52:12","AP02SDTM":"2022-08-01 12:52:12","AP02EDTM":"2023-08-01 18:52:12","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-19","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":144,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94296,"AVALU":"g/L","BASE2":2.91832,"BASE":2.79199,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02464,"PCHG2":0.84429,"CHG":0.15097,"PCHG":5.40725,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-20 00:52:12","ADY":384,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-41","SUBJID":"id-41","SITEID":"NGA-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":7.20651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-08-01 00:52:12","TRTEDTM":"2023-08-01 18:52:12","TRT01SDTM":"2020-08-01 00:52:12","TRT01EDTM":"2022-08-01 12:52:12","TRT02SDTM":"2022-08-01 12:52:12","TRT02EDTM":"2023-08-01 18:52:12","AP01SDTM":"2020-08-01 00:52:12","AP01EDTM":"2022-08-01 12:52:12","AP02SDTM":"2022-08-01 12:52:12","AP02EDTM":"2023-08-01 18:52:12","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-19","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6004,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97587,"AVALU":"g/L","BASE2":2.91832,"BASE":2.79199,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05756,"PCHG2":1.97226,"CHG":0.18389,"PCHG":6.58627,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-04 00:52:12","ADY":611,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-41","SUBJID":"id-41","SITEID":"NGA-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":7.20651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-08-01 00:52:12","TRTEDTM":"2023-08-01 18:52:12","TRT01SDTM":"2020-08-01 00:52:12","TRT01EDTM":"2022-08-01 12:52:12","TRT02SDTM":"2022-08-01 12:52:12","TRT02EDTM":"2023-08-01 18:52:12","AP01SDTM":"2020-08-01 00:52:12","AP01EDTM":"2022-08-01 12:52:12","AP02SDTM":"2022-08-01 12:52:12","AP02EDTM":"2023-08-01 18:52:12","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-19","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4467,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85839,"AVALU":"g/L","BASE2":2.91832,"BASE":2.79199,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05993,"PCHG2":-2.05357,"CHG":0.0664,"PCHG":2.37827,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-16 00:52:12","ADY":714,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-11-id-41","SUBJID":"id-41","SITEID":"NGA-11","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-11","INVNAM":"Dr. NGA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"B","STRATA2":"S2","BMRKR1":7.20651,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-28","TRTSDTM":"2020-08-01 00:52:12","TRTEDTM":"2023-08-01 18:52:12","TRT01SDTM":"2020-08-01 00:52:12","TRT01EDTM":"2022-08-01 12:52:12","TRT02SDTM":"2022-08-01 12:52:12","TRT02EDTM":"2023-08-01 18:52:12","AP01SDTM":"2020-08-01 00:52:12","AP01EDTM":"2022-08-01 12:52:12","AP02SDTM":"2022-08-01 12:52:12","AP02EDTM":"2023-08-01 18:52:12","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-01","EOSDY":1096,"LSTALVDT":"2023-08-19","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6281,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.69573,"AVALU":"g/L","BASE2":2.91832,"BASE":2.79199,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.22259,"PCHG2":-7.62726,"CHG":-0.09626,"PCHG":-3.44761,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-20 00:52:12","ADY":992,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-264","SUBJID":"id-264","SITEID":"NGA-12","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.82764,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-06","TRTSDTM":"2020-04-09 06:10:35","TRTEDTM":"2022-02-14 12:41:56","TRT01SDTM":"2020-04-09 06:10:35","TRT01EDTM":"2021-02-14 06:41:56","TRT02SDTM":"2021-02-14 06:41:56","TRT02EDTM":"2022-02-14 12:41:56","AP01SDTM":"2020-04-09 06:10:35","AP01EDTM":"2021-02-14 06:41:56","AP02SDTM":"2021-02-14 06:41:56","AP02EDTM":"2022-02-14 12:41:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":677,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":698,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4771,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.13541,"AVALU":"U/L","BASE2":6.13541,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-06-17 06:10:35","ADY":69,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-264","SUBJID":"id-264","SITEID":"NGA-12","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.82764,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-06","TRTSDTM":"2020-04-09 06:10:35","TRTEDTM":"2022-02-14 12:41:56","TRT01SDTM":"2020-04-09 06:10:35","TRT01EDTM":"2021-02-14 06:41:56","TRT02SDTM":"2021-02-14 06:41:56","TRT02EDTM":"2022-02-14 12:41:56","AP01SDTM":"2020-04-09 06:10:35","AP01EDTM":"2021-02-14 06:41:56","AP02SDTM":"2021-02-14 06:41:56","AP02EDTM":"2022-02-14 12:41:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":677,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":698,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":756,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.20415,"AVALU":"U/L","BASE2":6.13541,"BASE":17.20415,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":11.06873,"PCHG2":180.4073,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-13 06:10:35","ADY":95,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-264","SUBJID":"id-264","SITEID":"NGA-12","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.82764,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-06","TRTSDTM":"2020-04-09 06:10:35","TRTEDTM":"2022-02-14 12:41:56","TRT01SDTM":"2020-04-09 06:10:35","TRT01EDTM":"2021-02-14 06:41:56","TRT02SDTM":"2021-02-14 06:41:56","TRT02EDTM":"2022-02-14 12:41:56","AP01SDTM":"2020-04-09 06:10:35","AP01EDTM":"2021-02-14 06:41:56","AP02SDTM":"2021-02-14 06:41:56","AP02EDTM":"2022-02-14 12:41:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":677,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":698,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2102,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.16173,"AVALU":"U/L","BASE2":6.13541,"BASE":17.20415,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.02632,"PCHG2":130.81952,"CHG":-3.04242,"PCHG":-17.6842,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-09 06:10:35","ADY":214,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-264","SUBJID":"id-264","SITEID":"NGA-12","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.82764,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-06","TRTSDTM":"2020-04-09 06:10:35","TRTEDTM":"2022-02-14 12:41:56","TRT01SDTM":"2020-04-09 06:10:35","TRT01EDTM":"2021-02-14 06:41:56","TRT02SDTM":"2021-02-14 06:41:56","TRT02EDTM":"2022-02-14 12:41:56","AP01SDTM":"2020-04-09 06:10:35","AP01EDTM":"2021-02-14 06:41:56","AP02SDTM":"2021-02-14 06:41:56","AP02EDTM":"2022-02-14 12:41:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":677,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":698,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8192,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":44.34131,"AVALU":"U/L","BASE2":6.13541,"BASE":17.20415,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":38.2059,"PCHG2":622.71107,"CHG":27.13717,"PCHG":157.73618,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-08 06:10:35","ADY":243,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-264","SUBJID":"id-264","SITEID":"NGA-12","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.82764,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-06","TRTSDTM":"2020-04-09 06:10:35","TRTEDTM":"2022-02-14 12:41:56","TRT01SDTM":"2020-04-09 06:10:35","TRT01EDTM":"2021-02-14 06:41:56","TRT02SDTM":"2021-02-14 06:41:56","TRT02EDTM":"2022-02-14 12:41:56","AP01SDTM":"2020-04-09 06:10:35","AP01EDTM":"2021-02-14 06:41:56","AP02SDTM":"2021-02-14 06:41:56","AP02EDTM":"2022-02-14 12:41:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":677,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":698,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5465,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.9354,"AVALU":"U/L","BASE2":6.13541,"BASE":17.20415,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.79999,"PCHG2":224.92348,"CHG":2.73125,"PCHG":15.87554,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-07 06:10:35","ADY":304,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-264","SUBJID":"id-264","SITEID":"NGA-12","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.82764,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-06","TRTSDTM":"2020-04-09 06:10:35","TRTEDTM":"2022-02-14 12:41:56","TRT01SDTM":"2020-04-09 06:10:35","TRT01EDTM":"2021-02-14 06:41:56","TRT02SDTM":"2021-02-14 06:41:56","TRT02EDTM":"2022-02-14 12:41:56","AP01SDTM":"2020-04-09 06:10:35","AP01EDTM":"2021-02-14 06:41:56","AP02SDTM":"2021-02-14 06:41:56","AP02EDTM":"2022-02-14 12:41:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":677,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":698,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7894,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.38393,"AVALU":"U/L","BASE2":6.13541,"BASE":17.20415,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":24.24852,"PCHG2":395.22226,"CHG":13.17979,"PCHG":76.60819,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-23 06:10:35","ADY":320,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-264","SUBJID":"id-264","SITEID":"NGA-12","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.82764,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-06","TRTSDTM":"2020-04-09 06:10:35","TRTEDTM":"2022-02-14 12:41:56","TRT01SDTM":"2020-04-09 06:10:35","TRT01EDTM":"2021-02-14 06:41:56","TRT02SDTM":"2021-02-14 06:41:56","TRT02EDTM":"2022-02-14 12:41:56","AP01SDTM":"2020-04-09 06:10:35","AP01EDTM":"2021-02-14 06:41:56","AP02SDTM":"2021-02-14 06:41:56","AP02EDTM":"2022-02-14 12:41:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":677,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":698,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2337,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.65542,"AVALU":"U/L","BASE2":6.13541,"BASE":17.20415,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.52001,"PCHG2":252.95777,"CHG":4.45127,"PCHG":25.87324,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-02 06:10:35","ADY":358,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-264","SUBJID":"id-264","SITEID":"NGA-12","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.82764,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-06","TRTSDTM":"2020-04-09 06:10:35","TRTEDTM":"2022-02-14 12:41:56","TRT01SDTM":"2020-04-09 06:10:35","TRT01EDTM":"2021-02-14 06:41:56","TRT02SDTM":"2021-02-14 06:41:56","TRT02EDTM":"2022-02-14 12:41:56","AP01SDTM":"2020-04-09 06:10:35","AP01EDTM":"2021-02-14 06:41:56","AP02SDTM":"2021-02-14 06:41:56","AP02EDTM":"2022-02-14 12:41:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":677,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":698,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7884,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.93335,"AVALU":"mg/L","BASE2":9.93335,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-17 06:10:35","ADY":69,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-264","SUBJID":"id-264","SITEID":"NGA-12","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.82764,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-06","TRTSDTM":"2020-04-09 06:10:35","TRTEDTM":"2022-02-14 12:41:56","TRT01SDTM":"2020-04-09 06:10:35","TRT01EDTM":"2021-02-14 06:41:56","TRT02SDTM":"2021-02-14 06:41:56","TRT02EDTM":"2022-02-14 12:41:56","AP01SDTM":"2020-04-09 06:10:35","AP01EDTM":"2021-02-14 06:41:56","AP02SDTM":"2021-02-14 06:41:56","AP02EDTM":"2022-02-14 12:41:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":677,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":698,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8074,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.3908,"AVALU":"mg/L","BASE2":9.93335,"BASE":8.3908,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.54255,"PCHG2":-15.52902,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-13 06:10:35","ADY":95,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-264","SUBJID":"id-264","SITEID":"NGA-12","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.82764,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-06","TRTSDTM":"2020-04-09 06:10:35","TRTEDTM":"2022-02-14 12:41:56","TRT01SDTM":"2020-04-09 06:10:35","TRT01EDTM":"2021-02-14 06:41:56","TRT02SDTM":"2021-02-14 06:41:56","TRT02EDTM":"2022-02-14 12:41:56","AP01SDTM":"2020-04-09 06:10:35","AP01EDTM":"2021-02-14 06:41:56","AP02SDTM":"2021-02-14 06:41:56","AP02EDTM":"2022-02-14 12:41:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":677,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":698,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6617,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.93063,"AVALU":"mg/L","BASE2":9.93335,"BASE":8.3908,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.99727,"PCHG2":10.03965,"CHG":2.53983,"PCHG":30.26918,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-11-09 06:10:35","ADY":214,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-264","SUBJID":"id-264","SITEID":"NGA-12","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.82764,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-06","TRTSDTM":"2020-04-09 06:10:35","TRTEDTM":"2022-02-14 12:41:56","TRT01SDTM":"2020-04-09 06:10:35","TRT01EDTM":"2021-02-14 06:41:56","TRT02SDTM":"2021-02-14 06:41:56","TRT02EDTM":"2022-02-14 12:41:56","AP01SDTM":"2020-04-09 06:10:35","AP01EDTM":"2021-02-14 06:41:56","AP02SDTM":"2021-02-14 06:41:56","AP02EDTM":"2022-02-14 12:41:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":677,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":698,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":228,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.27583,"AVALU":"mg/L","BASE2":9.93335,"BASE":8.3908,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.65752,"PCHG2":-16.68641,"CHG":-0.11497,"PCHG":-1.37016,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-08 06:10:35","ADY":243,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-264","SUBJID":"id-264","SITEID":"NGA-12","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.82764,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-06","TRTSDTM":"2020-04-09 06:10:35","TRTEDTM":"2022-02-14 12:41:56","TRT01SDTM":"2020-04-09 06:10:35","TRT01EDTM":"2021-02-14 06:41:56","TRT02SDTM":"2021-02-14 06:41:56","TRT02EDTM":"2022-02-14 12:41:56","AP01SDTM":"2020-04-09 06:10:35","AP01EDTM":"2021-02-14 06:41:56","AP02SDTM":"2021-02-14 06:41:56","AP02EDTM":"2022-02-14 12:41:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":677,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":698,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2748,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.56552,"AVALU":"mg/L","BASE2":9.93335,"BASE":8.3908,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.36784,"PCHG2":-3.70303,"CHG":1.17472,"PCHG":14.00005,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-07 06:10:35","ADY":304,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-264","SUBJID":"id-264","SITEID":"NGA-12","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.82764,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-06","TRTSDTM":"2020-04-09 06:10:35","TRTEDTM":"2022-02-14 12:41:56","TRT01SDTM":"2020-04-09 06:10:35","TRT01EDTM":"2021-02-14 06:41:56","TRT02SDTM":"2021-02-14 06:41:56","TRT02EDTM":"2022-02-14 12:41:56","AP01SDTM":"2020-04-09 06:10:35","AP01EDTM":"2021-02-14 06:41:56","AP02SDTM":"2021-02-14 06:41:56","AP02EDTM":"2022-02-14 12:41:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":677,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":698,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7481,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.37995,"AVALU":"mg/L","BASE2":9.93335,"BASE":8.3908,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.5534,"PCHG2":-5.57112,"CHG":0.98915,"PCHG":11.78854,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-23 06:10:35","ADY":320,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-264","SUBJID":"id-264","SITEID":"NGA-12","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.82764,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-06","TRTSDTM":"2020-04-09 06:10:35","TRTEDTM":"2022-02-14 12:41:56","TRT01SDTM":"2020-04-09 06:10:35","TRT01EDTM":"2021-02-14 06:41:56","TRT02SDTM":"2021-02-14 06:41:56","TRT02EDTM":"2022-02-14 12:41:56","AP01SDTM":"2020-04-09 06:10:35","AP01EDTM":"2021-02-14 06:41:56","AP02SDTM":"2021-02-14 06:41:56","AP02EDTM":"2022-02-14 12:41:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":677,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":698,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":178,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.29414,"AVALU":"mg/L","BASE2":9.93335,"BASE":8.3908,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.63921,"PCHG2":-6.43502,"CHG":0.90334,"PCHG":10.76582,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-02 06:10:35","ADY":358,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-264","SUBJID":"id-264","SITEID":"NGA-12","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.82764,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-06","TRTSDTM":"2020-04-09 06:10:35","TRTEDTM":"2022-02-14 12:41:56","TRT01SDTM":"2020-04-09 06:10:35","TRT01EDTM":"2021-02-14 06:41:56","TRT02SDTM":"2021-02-14 06:41:56","TRT02EDTM":"2022-02-14 12:41:56","AP01SDTM":"2020-04-09 06:10:35","AP01EDTM":"2021-02-14 06:41:56","AP02SDTM":"2021-02-14 06:41:56","AP02EDTM":"2022-02-14 12:41:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":677,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":698,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8359,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89429,"AVALU":"g/L","BASE2":2.89429,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-17 06:10:35","ADY":69,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-264","SUBJID":"id-264","SITEID":"NGA-12","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.82764,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-06","TRTSDTM":"2020-04-09 06:10:35","TRTEDTM":"2022-02-14 12:41:56","TRT01SDTM":"2020-04-09 06:10:35","TRT01EDTM":"2021-02-14 06:41:56","TRT02SDTM":"2021-02-14 06:41:56","TRT02EDTM":"2022-02-14 12:41:56","AP01SDTM":"2020-04-09 06:10:35","AP01EDTM":"2021-02-14 06:41:56","AP02SDTM":"2021-02-14 06:41:56","AP02EDTM":"2022-02-14 12:41:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":677,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":698,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2725,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77363,"AVALU":"g/L","BASE2":2.89429,"BASE":2.77363,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.12066,"PCHG2":-4.1688,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-13 06:10:35","ADY":95,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-264","SUBJID":"id-264","SITEID":"NGA-12","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.82764,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-06","TRTSDTM":"2020-04-09 06:10:35","TRTEDTM":"2022-02-14 12:41:56","TRT01SDTM":"2020-04-09 06:10:35","TRT01EDTM":"2021-02-14 06:41:56","TRT02SDTM":"2021-02-14 06:41:56","TRT02EDTM":"2022-02-14 12:41:56","AP01SDTM":"2020-04-09 06:10:35","AP01EDTM":"2021-02-14 06:41:56","AP02SDTM":"2021-02-14 06:41:56","AP02EDTM":"2022-02-14 12:41:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":677,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":698,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3212,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01888,"AVALU":"g/L","BASE2":2.89429,"BASE":2.77363,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12459,"PCHG2":4.30471,"CHG":0.24525,"PCHG":8.84212,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-11-09 06:10:35","ADY":214,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-264","SUBJID":"id-264","SITEID":"NGA-12","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.82764,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-06","TRTSDTM":"2020-04-09 06:10:35","TRTEDTM":"2022-02-14 12:41:56","TRT01SDTM":"2020-04-09 06:10:35","TRT01EDTM":"2021-02-14 06:41:56","TRT02SDTM":"2021-02-14 06:41:56","TRT02EDTM":"2022-02-14 12:41:56","AP01SDTM":"2020-04-09 06:10:35","AP01EDTM":"2021-02-14 06:41:56","AP02SDTM":"2021-02-14 06:41:56","AP02EDTM":"2022-02-14 12:41:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":677,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":698,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2715,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80172,"AVALU":"g/L","BASE2":2.89429,"BASE":2.77363,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09257,"PCHG2":-3.19838,"CHG":0.02809,"PCHG":1.01264,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-08 06:10:35","ADY":243,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-264","SUBJID":"id-264","SITEID":"NGA-12","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.82764,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-06","TRTSDTM":"2020-04-09 06:10:35","TRTEDTM":"2022-02-14 12:41:56","TRT01SDTM":"2020-04-09 06:10:35","TRT01EDTM":"2021-02-14 06:41:56","TRT02SDTM":"2021-02-14 06:41:56","TRT02EDTM":"2022-02-14 12:41:56","AP01SDTM":"2020-04-09 06:10:35","AP01EDTM":"2021-02-14 06:41:56","AP02SDTM":"2021-02-14 06:41:56","AP02EDTM":"2022-02-14 12:41:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":677,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":698,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3840,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83291,"AVALU":"g/L","BASE2":2.89429,"BASE":2.77363,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06137,"PCHG2":-2.12049,"CHG":0.05928,"PCHG":2.13741,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-07 06:10:35","ADY":304,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-264","SUBJID":"id-264","SITEID":"NGA-12","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.82764,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-06","TRTSDTM":"2020-04-09 06:10:35","TRTEDTM":"2022-02-14 12:41:56","TRT01SDTM":"2020-04-09 06:10:35","TRT01EDTM":"2021-02-14 06:41:56","TRT02SDTM":"2021-02-14 06:41:56","TRT02EDTM":"2022-02-14 12:41:56","AP01SDTM":"2020-04-09 06:10:35","AP01EDTM":"2021-02-14 06:41:56","AP02SDTM":"2021-02-14 06:41:56","AP02EDTM":"2022-02-14 12:41:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":677,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":698,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3629,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95825,"AVALU":"g/L","BASE2":2.89429,"BASE":2.77363,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06396,"PCHG2":2.20997,"CHG":0.18462,"PCHG":6.65626,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-23 06:10:35","ADY":320,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-264","SUBJID":"id-264","SITEID":"NGA-12","AGE":24,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.82764,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-06","TRTSDTM":"2020-04-09 06:10:35","TRTEDTM":"2022-02-14 12:41:56","TRT01SDTM":"2020-04-09 06:10:35","TRT01EDTM":"2021-02-14 06:41:56","TRT02SDTM":"2021-02-14 06:41:56","TRT02EDTM":"2022-02-14 12:41:56","AP01SDTM":"2020-04-09 06:10:35","AP01EDTM":"2021-02-14 06:41:56","AP02SDTM":"2021-02-14 06:41:56","AP02EDTM":"2022-02-14 12:41:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":677,"DCSREAS":"DEATH","DTHDT":"2022-03-09","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":23,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-09","DTHADY":698,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4458,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93548,"AVALU":"g/L","BASE2":2.89429,"BASE":2.77363,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0412,"PCHG2":1.42336,"CHG":0.16185,"PCHG":5.83543,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-02 06:10:35","ADY":358,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-387","SUBJID":"id-387","SITEID":"NGA-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36861,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-05","TRTSDTM":"2020-01-07 17:07:38","TRT01SDTM":"2020-01-07 17:07:38","AP01SDTM":"2020-01-07 17:07:38","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":784,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.05802,"AVALU":"U/L","BASE2":19.05802,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-21 17:07:38","ADY":74,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-387","SUBJID":"id-387","SITEID":"NGA-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36861,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-05","TRTSDTM":"2020-01-07 17:07:38","TRT01SDTM":"2020-01-07 17:07:38","AP01SDTM":"2020-01-07 17:07:38","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7953,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.17294,"AVALU":"U/L","BASE2":19.05802,"BASE":15.17294,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-3.88509,"PCHG2":-20.38558,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-24 17:07:38","ADY":473,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-387","SUBJID":"id-387","SITEID":"NGA-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36861,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-05","TRTSDTM":"2020-01-07 17:07:38","TRT01SDTM":"2020-01-07 17:07:38","AP01SDTM":"2020-01-07 17:07:38","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2189,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.06778,"AVALU":"U/L","BASE2":19.05802,"BASE":15.17294,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.99024,"PCHG2":-26.18446,"CHG":-1.10515,"PCHG":-7.28372,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-12 17:07:38","ADY":522,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-387","SUBJID":"id-387","SITEID":"NGA-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36861,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-05","TRTSDTM":"2020-01-07 17:07:38","TRT01SDTM":"2020-01-07 17:07:38","AP01SDTM":"2020-01-07 17:07:38","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7300,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.77906,"AVALU":"U/L","BASE2":19.05802,"BASE":15.17294,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.72103,"PCHG2":30.01902,"CHG":9.60612,"PCHG":63.31088,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-22 17:07:38","ADY":624,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-387","SUBJID":"id-387","SITEID":"NGA-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36861,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-05","TRTSDTM":"2020-01-07 17:07:38","TRT01SDTM":"2020-01-07 17:07:38","AP01SDTM":"2020-01-07 17:07:38","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6890,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.97425,"AVALU":"U/L","BASE2":19.05802,"BASE":15.17294,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.91623,"PCHG2":57.27892,"CHG":14.80132,"PCHG":97.55079,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-14 17:07:38","ADY":646,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-387","SUBJID":"id-387","SITEID":"NGA-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36861,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-05","TRTSDTM":"2020-01-07 17:07:38","TRT01SDTM":"2020-01-07 17:07:38","AP01SDTM":"2020-01-07 17:07:38","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4303,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.80524,"AVALU":"U/L","BASE2":19.05802,"BASE":15.17294,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.25278,"PCHG2":-22.31493,"CHG":-0.3677,"PCHG":-2.42337,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-05 17:07:38","ADY":668,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-387","SUBJID":"id-387","SITEID":"NGA-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36861,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-05","TRTSDTM":"2020-01-07 17:07:38","TRT01SDTM":"2020-01-07 17:07:38","AP01SDTM":"2020-01-07 17:07:38","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6679,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.79889,"AVALU":"U/L","BASE2":19.05802,"BASE":15.17294,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.74086,"PCHG2":40.61735,"CHG":11.62595,"PCHG":76.62296,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-19 17:07:38","ADY":712,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-387","SUBJID":"id-387","SITEID":"NGA-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36861,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-05","TRTSDTM":"2020-01-07 17:07:38","TRT01SDTM":"2020-01-07 17:07:38","AP01SDTM":"2020-01-07 17:07:38","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6988,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.32284,"AVALU":"mg/L","BASE2":10.32284,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-03-21 17:07:38","ADY":74,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-387","SUBJID":"id-387","SITEID":"NGA-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36861,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-05","TRTSDTM":"2020-01-07 17:07:38","TRT01SDTM":"2020-01-07 17:07:38","AP01SDTM":"2020-01-07 17:07:38","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5737,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.30132,"AVALU":"mg/L","BASE2":10.32284,"BASE":8.30132,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.02152,"PCHG2":-19.58301,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-24 17:07:38","ADY":473,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-387","SUBJID":"id-387","SITEID":"NGA-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36861,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-05","TRTSDTM":"2020-01-07 17:07:38","TRT01SDTM":"2020-01-07 17:07:38","AP01SDTM":"2020-01-07 17:07:38","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":849,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.89974,"AVALU":"mg/L","BASE2":10.32284,"BASE":8.30132,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.4231,"PCHG2":-13.7859,"CHG":0.59843,"PCHG":7.2088,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-12 17:07:38","ADY":522,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-387","SUBJID":"id-387","SITEID":"NGA-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36861,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-05","TRTSDTM":"2020-01-07 17:07:38","TRT01SDTM":"2020-01-07 17:07:38","AP01SDTM":"2020-01-07 17:07:38","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2475,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.36112,"AVALU":"mg/L","BASE2":10.32284,"BASE":8.30132,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03828,"PCHG2":0.37088,"CHG":2.05981,"PCHG":24.81302,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-09-22 17:07:38","ADY":624,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-387","SUBJID":"id-387","SITEID":"NGA-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36861,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-05","TRTSDTM":"2020-01-07 17:07:38","TRT01SDTM":"2020-01-07 17:07:38","AP01SDTM":"2020-01-07 17:07:38","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3220,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.13389,"AVALU":"mg/L","BASE2":10.32284,"BASE":8.30132,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.18895,"PCHG2":-21.20492,"CHG":-0.16743,"PCHG":-2.01689,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-14 17:07:38","ADY":646,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-387","SUBJID":"id-387","SITEID":"NGA-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36861,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-05","TRTSDTM":"2020-01-07 17:07:38","TRT01SDTM":"2020-01-07 17:07:38","AP01SDTM":"2020-01-07 17:07:38","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3046,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.65876,"AVALU":"mg/L","BASE2":10.32284,"BASE":8.30132,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.66407,"PCHG2":-16.12032,"CHG":0.35745,"PCHG":4.30592,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-05 17:07:38","ADY":668,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-387","SUBJID":"id-387","SITEID":"NGA-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36861,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-05","TRTSDTM":"2020-01-07 17:07:38","TRT01SDTM":"2020-01-07 17:07:38","AP01SDTM":"2020-01-07 17:07:38","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5088,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.88122,"AVALU":"mg/L","BASE2":10.32284,"BASE":8.30132,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.44162,"PCHG2":-4.27812,"CHG":1.5799,"PCHG":19.0319,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-19 17:07:38","ADY":712,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-387","SUBJID":"id-387","SITEID":"NGA-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36861,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-05","TRTSDTM":"2020-01-07 17:07:38","TRT01SDTM":"2020-01-07 17:07:38","AP01SDTM":"2020-01-07 17:07:38","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6521,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90357,"AVALU":"g/L","BASE2":2.90357,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-03-21 17:07:38","ADY":74,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-387","SUBJID":"id-387","SITEID":"NGA-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36861,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-05","TRTSDTM":"2020-01-07 17:07:38","TRT01SDTM":"2020-01-07 17:07:38","AP01SDTM":"2020-01-07 17:07:38","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1126,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01311,"AVALU":"g/L","BASE2":2.90357,"BASE":3.01311,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.10954,"PCHG2":3.77268,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2021-04-24 17:07:38","ADY":473,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-387","SUBJID":"id-387","SITEID":"NGA-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36861,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-05","TRTSDTM":"2020-01-07 17:07:38","TRT01SDTM":"2020-01-07 17:07:38","AP01SDTM":"2020-01-07 17:07:38","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3288,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.18089,"AVALU":"g/L","BASE2":2.90357,"BASE":3.01311,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.27732,"PCHG2":9.55092,"CHG":0.16778,"PCHG":5.56817,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"3","BTOXGR":"3","ADTM":"2021-06-12 17:07:38","ADY":522,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-387","SUBJID":"id-387","SITEID":"NGA-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36861,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-05","TRTSDTM":"2020-01-07 17:07:38","TRT01SDTM":"2020-01-07 17:07:38","AP01SDTM":"2020-01-07 17:07:38","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1288,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.09873,"AVALU":"g/L","BASE2":2.90357,"BASE":3.01311,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.19516,"PCHG2":6.72138,"CHG":0.08562,"PCHG":2.8415,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"3","ADTM":"2021-09-22 17:07:38","ADY":624,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-387","SUBJID":"id-387","SITEID":"NGA-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36861,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-05","TRTSDTM":"2020-01-07 17:07:38","TRT01SDTM":"2020-01-07 17:07:38","AP01SDTM":"2020-01-07 17:07:38","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5126,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88456,"AVALU":"g/L","BASE2":2.90357,"BASE":3.01311,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01901,"PCHG2":-0.65466,"CHG":-0.12855,"PCHG":-4.26639,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-10-14 17:07:38","ADY":646,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-387","SUBJID":"id-387","SITEID":"NGA-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36861,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-05","TRTSDTM":"2020-01-07 17:07:38","TRT01SDTM":"2020-01-07 17:07:38","AP01SDTM":"2020-01-07 17:07:38","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8211,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00446,"AVALU":"g/L","BASE2":2.90357,"BASE":3.01311,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10089,"PCHG2":3.47481,"CHG":-0.00865,"PCHG":-0.28705,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"1","BTOXGR":"3","ADTM":"2021-11-05 17:07:38","ADY":668,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-12-id-387","SUBJID":"id-387","SITEID":"NGA-12","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-12","INVNAM":"Dr. NGA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.36861,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-05","TRTSDTM":"2020-01-07 17:07:38","TRT01SDTM":"2020-01-07 17:07:38","AP01SDTM":"2020-01-07 17:07:38","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6630,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.72327,"AVALU":"g/L","BASE2":2.90357,"BASE":3.01311,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1803,"PCHG2":-6.20951,"CHG":-0.28984,"PCHG":-9.61929,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-12-19 17:07:38","ADY":712,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-230","SUBJID":"id-230","SITEID":"NGA-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":17.67234,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-05 16:01:31","TRTEDTM":"2023-05-06 10:01:31","TRT01SDTM":"2020-05-05 16:01:31","TRT01EDTM":"2022-05-06 04:01:31","TRT02SDTM":"2022-05-06 04:01:31","TRT02EDTM":"2023-05-06 10:01:31","AP01SDTM":"2020-05-05 16:01:31","AP01EDTM":"2022-05-06 04:01:31","AP02SDTM":"2022-05-06 04:01:31","AP02EDTM":"2023-05-06 10:01:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-06","EOSDY":1096,"LSTALVDT":"2023-05-25","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1859,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.33879,"AVALU":"U/L","BASE2":16.33879,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-15 16:01:31","ADY":41,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-230","SUBJID":"id-230","SITEID":"NGA-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":17.67234,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-05 16:01:31","TRTEDTM":"2023-05-06 10:01:31","TRT01SDTM":"2020-05-05 16:01:31","TRT01EDTM":"2022-05-06 04:01:31","TRT02SDTM":"2022-05-06 04:01:31","TRT02EDTM":"2023-05-06 10:01:31","AP01SDTM":"2020-05-05 16:01:31","AP01EDTM":"2022-05-06 04:01:31","AP02SDTM":"2022-05-06 04:01:31","AP02EDTM":"2023-05-06 10:01:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-06","EOSDY":1096,"LSTALVDT":"2023-05-25","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2083,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.33561,"AVALU":"U/L","BASE2":16.33879,"BASE":20.33561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":3.99682,"PCHG2":24.46213,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-17 16:01:31","ADY":196,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-230","SUBJID":"id-230","SITEID":"NGA-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":17.67234,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-05 16:01:31","TRTEDTM":"2023-05-06 10:01:31","TRT01SDTM":"2020-05-05 16:01:31","TRT01EDTM":"2022-05-06 04:01:31","TRT02SDTM":"2022-05-06 04:01:31","TRT02EDTM":"2023-05-06 10:01:31","AP01SDTM":"2020-05-05 16:01:31","AP01EDTM":"2022-05-06 04:01:31","AP02SDTM":"2022-05-06 04:01:31","AP02EDTM":"2023-05-06 10:01:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-06","EOSDY":1096,"LSTALVDT":"2023-05-25","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8153,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.24592,"AVALU":"U/L","BASE2":16.33879,"BASE":20.33561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.90713,"PCHG2":60.63564,"CHG":5.91031,"PCHG":29.06387,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-22 16:01:31","ADY":382,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-230","SUBJID":"id-230","SITEID":"NGA-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":17.67234,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-05 16:01:31","TRTEDTM":"2023-05-06 10:01:31","TRT01SDTM":"2020-05-05 16:01:31","TRT01EDTM":"2022-05-06 04:01:31","TRT02SDTM":"2022-05-06 04:01:31","TRT02EDTM":"2023-05-06 10:01:31","AP01SDTM":"2020-05-05 16:01:31","AP01EDTM":"2022-05-06 04:01:31","AP02SDTM":"2022-05-06 04:01:31","AP02EDTM":"2023-05-06 10:01:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-06","EOSDY":1096,"LSTALVDT":"2023-05-25","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1061,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.39836,"AVALU":"U/L","BASE2":16.33879,"BASE":20.33561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.94043,"PCHG2":-5.75579,"CHG":-4.93724,"PCHG":-24.27881,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-12 16:01:31","ADY":586,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-230","SUBJID":"id-230","SITEID":"NGA-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":17.67234,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-05 16:01:31","TRTEDTM":"2023-05-06 10:01:31","TRT01SDTM":"2020-05-05 16:01:31","TRT01EDTM":"2022-05-06 04:01:31","TRT02SDTM":"2022-05-06 04:01:31","TRT02EDTM":"2023-05-06 10:01:31","AP01SDTM":"2020-05-05 16:01:31","AP01EDTM":"2022-05-06 04:01:31","AP02SDTM":"2022-05-06 04:01:31","AP02EDTM":"2023-05-06 10:01:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-06","EOSDY":1096,"LSTALVDT":"2023-05-25","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5596,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.76109,"AVALU":"U/L","BASE2":16.33879,"BASE":20.33561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.5777,"PCHG2":-34.13776,"CHG":-9.57451,"PCHG":-47.08251,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-27 16:01:31","ADY":905,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-230","SUBJID":"id-230","SITEID":"NGA-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":17.67234,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-05 16:01:31","TRTEDTM":"2023-05-06 10:01:31","TRT01SDTM":"2020-05-05 16:01:31","TRT01EDTM":"2022-05-06 04:01:31","TRT02SDTM":"2022-05-06 04:01:31","TRT02EDTM":"2023-05-06 10:01:31","AP01SDTM":"2020-05-05 16:01:31","AP01EDTM":"2022-05-06 04:01:31","AP02SDTM":"2022-05-06 04:01:31","AP02EDTM":"2023-05-06 10:01:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-06","EOSDY":1096,"LSTALVDT":"2023-05-25","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6901,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":41.00756,"AVALU":"U/L","BASE2":16.33879,"BASE":20.33561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":24.66877,"PCHG2":150.98283,"CHG":20.67195,"PCHG":101.65397,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-24 16:01:31","ADY":933,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-230","SUBJID":"id-230","SITEID":"NGA-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":17.67234,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-05 16:01:31","TRTEDTM":"2023-05-06 10:01:31","TRT01SDTM":"2020-05-05 16:01:31","TRT01EDTM":"2022-05-06 04:01:31","TRT02SDTM":"2022-05-06 04:01:31","TRT02EDTM":"2023-05-06 10:01:31","AP01SDTM":"2020-05-05 16:01:31","AP01EDTM":"2022-05-06 04:01:31","AP02SDTM":"2022-05-06 04:01:31","AP02EDTM":"2023-05-06 10:01:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-06","EOSDY":1096,"LSTALVDT":"2023-05-25","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6293,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.82399,"AVALU":"U/L","BASE2":16.33879,"BASE":20.33561,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.4852,"PCHG2":70.29409,"CHG":7.48839,"PCHG":36.82402,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-15 16:01:31","ADY":1075,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-230","SUBJID":"id-230","SITEID":"NGA-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":17.67234,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-05 16:01:31","TRTEDTM":"2023-05-06 10:01:31","TRT01SDTM":"2020-05-05 16:01:31","TRT01EDTM":"2022-05-06 04:01:31","TRT02SDTM":"2022-05-06 04:01:31","TRT02EDTM":"2023-05-06 10:01:31","AP01SDTM":"2020-05-05 16:01:31","AP01EDTM":"2022-05-06 04:01:31","AP02SDTM":"2022-05-06 04:01:31","AP02EDTM":"2023-05-06 10:01:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-06","EOSDY":1096,"LSTALVDT":"2023-05-25","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7211,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.21418,"AVALU":"mg/L","BASE2":7.21418,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-06-15 16:01:31","ADY":41,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-230","SUBJID":"id-230","SITEID":"NGA-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":17.67234,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-05 16:01:31","TRTEDTM":"2023-05-06 10:01:31","TRT01SDTM":"2020-05-05 16:01:31","TRT01EDTM":"2022-05-06 04:01:31","TRT02SDTM":"2022-05-06 04:01:31","TRT02EDTM":"2023-05-06 10:01:31","AP01SDTM":"2020-05-05 16:01:31","AP01EDTM":"2022-05-06 04:01:31","AP02SDTM":"2022-05-06 04:01:31","AP02EDTM":"2023-05-06 10:01:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-06","EOSDY":1096,"LSTALVDT":"2023-05-25","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5090,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.32839,"AVALU":"mg/L","BASE2":7.21418,"BASE":9.32839,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.11421,"PCHG2":29.30624,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-17 16:01:31","ADY":196,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-230","SUBJID":"id-230","SITEID":"NGA-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":17.67234,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-05 16:01:31","TRTEDTM":"2023-05-06 10:01:31","TRT01SDTM":"2020-05-05 16:01:31","TRT01EDTM":"2022-05-06 04:01:31","TRT02SDTM":"2022-05-06 04:01:31","TRT02EDTM":"2023-05-06 10:01:31","AP01SDTM":"2020-05-05 16:01:31","AP01EDTM":"2022-05-06 04:01:31","AP02SDTM":"2022-05-06 04:01:31","AP02EDTM":"2023-05-06 10:01:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-06","EOSDY":1096,"LSTALVDT":"2023-05-25","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4426,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.63893,"AVALU":"mg/L","BASE2":7.21418,"BASE":9.32839,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.42475,"PCHG2":47.47242,"CHG":1.31054,"PCHG":14.04896,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-05-22 16:01:31","ADY":382,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-230","SUBJID":"id-230","SITEID":"NGA-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":17.67234,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-05 16:01:31","TRTEDTM":"2023-05-06 10:01:31","TRT01SDTM":"2020-05-05 16:01:31","TRT01EDTM":"2022-05-06 04:01:31","TRT02SDTM":"2022-05-06 04:01:31","TRT02EDTM":"2023-05-06 10:01:31","AP01SDTM":"2020-05-05 16:01:31","AP01EDTM":"2022-05-06 04:01:31","AP02SDTM":"2022-05-06 04:01:31","AP02EDTM":"2023-05-06 10:01:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-06","EOSDY":1096,"LSTALVDT":"2023-05-25","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4722,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.95352,"AVALU":"mg/L","BASE2":7.21418,"BASE":9.32839,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.73933,"PCHG2":37.97148,"CHG":0.62513,"PCHG":6.70133,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-12 16:01:31","ADY":586,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-230","SUBJID":"id-230","SITEID":"NGA-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":17.67234,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-05 16:01:31","TRTEDTM":"2023-05-06 10:01:31","TRT01SDTM":"2020-05-05 16:01:31","TRT01EDTM":"2022-05-06 04:01:31","TRT02SDTM":"2022-05-06 04:01:31","TRT02EDTM":"2023-05-06 10:01:31","AP01SDTM":"2020-05-05 16:01:31","AP01EDTM":"2022-05-06 04:01:31","AP02SDTM":"2022-05-06 04:01:31","AP02EDTM":"2023-05-06 10:01:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-06","EOSDY":1096,"LSTALVDT":"2023-05-25","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2268,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.14204,"AVALU":"mg/L","BASE2":7.21418,"BASE":9.32839,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.92786,"PCHG2":54.4463,"CHG":1.81365,"PCHG":19.44226,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-10-27 16:01:31","ADY":905,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-230","SUBJID":"id-230","SITEID":"NGA-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":17.67234,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-05 16:01:31","TRTEDTM":"2023-05-06 10:01:31","TRT01SDTM":"2020-05-05 16:01:31","TRT01EDTM":"2022-05-06 04:01:31","TRT02SDTM":"2022-05-06 04:01:31","TRT02EDTM":"2023-05-06 10:01:31","AP01SDTM":"2020-05-05 16:01:31","AP01EDTM":"2022-05-06 04:01:31","AP02SDTM":"2022-05-06 04:01:31","AP02EDTM":"2023-05-06 10:01:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-06","EOSDY":1096,"LSTALVDT":"2023-05-25","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4048,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.67147,"AVALU":"mg/L","BASE2":7.21418,"BASE":9.32839,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.45729,"PCHG2":20.20028,"CHG":-0.65692,"PCHG":-7.04217,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-24 16:01:31","ADY":933,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-230","SUBJID":"id-230","SITEID":"NGA-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":17.67234,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-05 16:01:31","TRTEDTM":"2023-05-06 10:01:31","TRT01SDTM":"2020-05-05 16:01:31","TRT01EDTM":"2022-05-06 04:01:31","TRT02SDTM":"2022-05-06 04:01:31","TRT02EDTM":"2023-05-06 10:01:31","AP01SDTM":"2020-05-05 16:01:31","AP01EDTM":"2022-05-06 04:01:31","AP02SDTM":"2022-05-06 04:01:31","AP02EDTM":"2023-05-06 10:01:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-06","EOSDY":1096,"LSTALVDT":"2023-05-25","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3551,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.43403,"AVALU":"mg/L","BASE2":7.21418,"BASE":9.32839,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.21984,"PCHG2":16.90895,"CHG":-0.89436,"PCHG":-9.58754,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-15 16:01:31","ADY":1075,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-230","SUBJID":"id-230","SITEID":"NGA-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":17.67234,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-05 16:01:31","TRTEDTM":"2023-05-06 10:01:31","TRT01SDTM":"2020-05-05 16:01:31","TRT01EDTM":"2022-05-06 04:01:31","TRT02SDTM":"2022-05-06 04:01:31","TRT02EDTM":"2023-05-06 10:01:31","AP01SDTM":"2020-05-05 16:01:31","AP01EDTM":"2022-05-06 04:01:31","AP02SDTM":"2022-05-06 04:01:31","AP02EDTM":"2023-05-06 10:01:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-06","EOSDY":1096,"LSTALVDT":"2023-05-25","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2679,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.07963,"AVALU":"g/L","BASE2":3.07963,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-06-15 16:01:31","ADY":41,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-230","SUBJID":"id-230","SITEID":"NGA-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":17.67234,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-05 16:01:31","TRTEDTM":"2023-05-06 10:01:31","TRT01SDTM":"2020-05-05 16:01:31","TRT01EDTM":"2022-05-06 04:01:31","TRT02SDTM":"2022-05-06 04:01:31","TRT02EDTM":"2023-05-06 10:01:31","AP01SDTM":"2020-05-05 16:01:31","AP01EDTM":"2022-05-06 04:01:31","AP02SDTM":"2022-05-06 04:01:31","AP02EDTM":"2023-05-06 10:01:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-06","EOSDY":1096,"LSTALVDT":"2023-05-25","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3943,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91405,"AVALU":"g/L","BASE2":3.07963,"BASE":2.91405,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.16558,"PCHG2":-5.37678,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-17 16:01:31","ADY":196,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-230","SUBJID":"id-230","SITEID":"NGA-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":17.67234,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-05 16:01:31","TRTEDTM":"2023-05-06 10:01:31","TRT01SDTM":"2020-05-05 16:01:31","TRT01EDTM":"2022-05-06 04:01:31","TRT02SDTM":"2022-05-06 04:01:31","TRT02EDTM":"2023-05-06 10:01:31","AP01SDTM":"2020-05-05 16:01:31","AP01EDTM":"2022-05-06 04:01:31","AP02SDTM":"2022-05-06 04:01:31","AP02EDTM":"2023-05-06 10:01:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-06","EOSDY":1096,"LSTALVDT":"2023-05-25","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6408,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9007,"AVALU":"g/L","BASE2":3.07963,"BASE":2.91405,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17893,"PCHG2":-5.81017,"CHG":-0.01335,"PCHG":-0.45801,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-22 16:01:31","ADY":382,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-230","SUBJID":"id-230","SITEID":"NGA-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":17.67234,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-05 16:01:31","TRTEDTM":"2023-05-06 10:01:31","TRT01SDTM":"2020-05-05 16:01:31","TRT01EDTM":"2022-05-06 04:01:31","TRT02SDTM":"2022-05-06 04:01:31","TRT02EDTM":"2023-05-06 10:01:31","AP01SDTM":"2020-05-05 16:01:31","AP01EDTM":"2022-05-06 04:01:31","AP02SDTM":"2022-05-06 04:01:31","AP02EDTM":"2023-05-06 10:01:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-06","EOSDY":1096,"LSTALVDT":"2023-05-25","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5063,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93567,"AVALU":"g/L","BASE2":3.07963,"BASE":2.91405,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14396,"PCHG2":-4.67462,"CHG":0.02162,"PCHG":0.74206,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-12 16:01:31","ADY":586,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-230","SUBJID":"id-230","SITEID":"NGA-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":17.67234,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-05 16:01:31","TRTEDTM":"2023-05-06 10:01:31","TRT01SDTM":"2020-05-05 16:01:31","TRT01EDTM":"2022-05-06 04:01:31","TRT02SDTM":"2022-05-06 04:01:31","TRT02EDTM":"2023-05-06 10:01:31","AP01SDTM":"2020-05-05 16:01:31","AP01EDTM":"2022-05-06 04:01:31","AP02SDTM":"2022-05-06 04:01:31","AP02EDTM":"2023-05-06 10:01:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-06","EOSDY":1096,"LSTALVDT":"2023-05-25","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1924,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81313,"AVALU":"g/L","BASE2":3.07963,"BASE":2.91405,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.2665,"PCHG2":-8.65374,"CHG":-0.10092,"PCHG":-3.46317,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-27 16:01:31","ADY":905,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-230","SUBJID":"id-230","SITEID":"NGA-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":17.67234,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-05 16:01:31","TRTEDTM":"2023-05-06 10:01:31","TRT01SDTM":"2020-05-05 16:01:31","TRT01EDTM":"2022-05-06 04:01:31","TRT02SDTM":"2022-05-06 04:01:31","TRT02EDTM":"2023-05-06 10:01:31","AP01SDTM":"2020-05-05 16:01:31","AP01EDTM":"2022-05-06 04:01:31","AP02SDTM":"2022-05-06 04:01:31","AP02EDTM":"2023-05-06 10:01:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-06","EOSDY":1096,"LSTALVDT":"2023-05-25","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4700,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93507,"AVALU":"g/L","BASE2":3.07963,"BASE":2.91405,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14456,"PCHG2":-4.69422,"CHG":0.02102,"PCHG":0.72135,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-24 16:01:31","ADY":933,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-230","SUBJID":"id-230","SITEID":"NGA-17","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":17.67234,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-05-05","TRTSDTM":"2020-05-05 16:01:31","TRTEDTM":"2023-05-06 10:01:31","TRT01SDTM":"2020-05-05 16:01:31","TRT01EDTM":"2022-05-06 04:01:31","TRT02SDTM":"2022-05-06 04:01:31","TRT02EDTM":"2023-05-06 10:01:31","AP01SDTM":"2020-05-05 16:01:31","AP01EDTM":"2022-05-06 04:01:31","AP02SDTM":"2022-05-06 04:01:31","AP02EDTM":"2023-05-06 10:01:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-05-06","EOSDY":1096,"LSTALVDT":"2023-05-25","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":221,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94859,"AVALU":"g/L","BASE2":3.07963,"BASE":2.91405,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13104,"PCHG2":-4.25513,"CHG":0.03454,"PCHG":1.18539,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-15 16:01:31","ADY":1075,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-72","SUBJID":"id-72","SITEID":"NGA-17","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.40254,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-11 13:31:34","TRTEDTM":"2022-09-11 07:31:34","TRT01SDTM":"2019-09-11 13:31:34","TRT01EDTM":"2021-09-11 01:31:34","TRT02SDTM":"2021-09-11 01:31:34","TRT02EDTM":"2022-09-11 07:31:34","AP01SDTM":"2019-09-11 13:31:34","AP01EDTM":"2021-09-11 01:31:34","AP02SDTM":"2021-09-11 01:31:34","AP02EDTM":"2022-09-11 07:31:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-10-10","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5622,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.26735,"AVALU":"U/L","BASE2":12.26735,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-01 13:31:34","ADY":20,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-72","SUBJID":"id-72","SITEID":"NGA-17","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.40254,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-11 13:31:34","TRTEDTM":"2022-09-11 07:31:34","TRT01SDTM":"2019-09-11 13:31:34","TRT01EDTM":"2021-09-11 01:31:34","TRT02SDTM":"2021-09-11 01:31:34","TRT02EDTM":"2022-09-11 07:31:34","AP01SDTM":"2019-09-11 13:31:34","AP01EDTM":"2021-09-11 01:31:34","AP02SDTM":"2021-09-11 01:31:34","AP02EDTM":"2022-09-11 07:31:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-10-10","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":108,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.45808,"AVALU":"U/L","BASE2":12.26735,"BASE":22.45808,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":10.19073,"PCHG2":83.07203,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-29 13:31:34","ADY":506,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-72","SUBJID":"id-72","SITEID":"NGA-17","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.40254,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-11 13:31:34","TRTEDTM":"2022-09-11 07:31:34","TRT01SDTM":"2019-09-11 13:31:34","TRT01EDTM":"2021-09-11 01:31:34","TRT02SDTM":"2021-09-11 01:31:34","TRT02EDTM":"2022-09-11 07:31:34","AP01SDTM":"2019-09-11 13:31:34","AP01EDTM":"2021-09-11 01:31:34","AP02SDTM":"2021-09-11 01:31:34","AP02EDTM":"2022-09-11 07:31:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-10-10","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1188,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.41561,"AVALU":"U/L","BASE2":12.26735,"BASE":22.45808,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.14826,"PCHG2":58.27064,"CHG":-3.04247,"PCHG":-13.54734,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-23 13:31:34","ADY":620,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-72","SUBJID":"id-72","SITEID":"NGA-17","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.40254,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-11 13:31:34","TRTEDTM":"2022-09-11 07:31:34","TRT01SDTM":"2019-09-11 13:31:34","TRT01EDTM":"2021-09-11 01:31:34","TRT02SDTM":"2021-09-11 01:31:34","TRT02EDTM":"2022-09-11 07:31:34","AP01SDTM":"2019-09-11 13:31:34","AP01EDTM":"2021-09-11 01:31:34","AP02SDTM":"2021-09-11 01:31:34","AP02EDTM":"2022-09-11 07:31:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-10-10","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4026,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.89588,"AVALU":"U/L","BASE2":12.26735,"BASE":22.45808,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.62854,"PCHG2":94.79261,"CHG":1.4378,"PCHG":6.40216,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-05 13:31:34","ADY":725,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-72","SUBJID":"id-72","SITEID":"NGA-17","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.40254,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-11 13:31:34","TRTEDTM":"2022-09-11 07:31:34","TRT01SDTM":"2019-09-11 13:31:34","TRT01EDTM":"2021-09-11 01:31:34","TRT02SDTM":"2021-09-11 01:31:34","TRT02EDTM":"2022-09-11 07:31:34","AP01SDTM":"2019-09-11 13:31:34","AP01EDTM":"2021-09-11 01:31:34","AP02SDTM":"2021-09-11 01:31:34","AP02EDTM":"2022-09-11 07:31:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-10-10","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3508,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.05854,"AVALU":"U/L","BASE2":12.26735,"BASE":22.45808,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.7912,"PCHG2":87.96684,"CHG":0.60046,"PCHG":2.6737,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-20 13:31:34","ADY":770,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-72","SUBJID":"id-72","SITEID":"NGA-17","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.40254,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-11 13:31:34","TRTEDTM":"2022-09-11 07:31:34","TRT01SDTM":"2019-09-11 13:31:34","TRT01EDTM":"2021-09-11 01:31:34","TRT02SDTM":"2021-09-11 01:31:34","TRT02EDTM":"2022-09-11 07:31:34","AP01SDTM":"2019-09-11 13:31:34","AP01EDTM":"2021-09-11 01:31:34","AP02SDTM":"2021-09-11 01:31:34","AP02EDTM":"2022-09-11 07:31:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-10-10","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7541,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.35366,"AVALU":"U/L","BASE2":12.26735,"BASE":22.45808,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08631,"PCHG2":0.70357,"CHG":-10.10442,"PCHG":-44.99238,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-11 13:31:34","ADY":884,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-72","SUBJID":"id-72","SITEID":"NGA-17","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.40254,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-11 13:31:34","TRTEDTM":"2022-09-11 07:31:34","TRT01SDTM":"2019-09-11 13:31:34","TRT01EDTM":"2021-09-11 01:31:34","TRT02SDTM":"2021-09-11 01:31:34","TRT02EDTM":"2022-09-11 07:31:34","AP01SDTM":"2019-09-11 13:31:34","AP01EDTM":"2021-09-11 01:31:34","AP02SDTM":"2021-09-11 01:31:34","AP02EDTM":"2022-09-11 07:31:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-10-10","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4369,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.51597,"AVALU":"U/L","BASE2":12.26735,"BASE":22.45808,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.75137,"PCHG2":-46.8836,"CHG":-15.94211,"PCHG":-70.98606,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2022-06-17 13:31:34","ADY":1010,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-72","SUBJID":"id-72","SITEID":"NGA-17","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.40254,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-11 13:31:34","TRTEDTM":"2022-09-11 07:31:34","TRT01SDTM":"2019-09-11 13:31:34","TRT01EDTM":"2021-09-11 01:31:34","TRT02SDTM":"2021-09-11 01:31:34","TRT02EDTM":"2022-09-11 07:31:34","AP01SDTM":"2019-09-11 13:31:34","AP01EDTM":"2021-09-11 01:31:34","AP02SDTM":"2021-09-11 01:31:34","AP02EDTM":"2022-09-11 07:31:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-10-10","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2787,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.44889,"AVALU":"mg/L","BASE2":9.44889,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-01 13:31:34","ADY":20,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-72","SUBJID":"id-72","SITEID":"NGA-17","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.40254,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-11 13:31:34","TRTEDTM":"2022-09-11 07:31:34","TRT01SDTM":"2019-09-11 13:31:34","TRT01EDTM":"2021-09-11 01:31:34","TRT02SDTM":"2021-09-11 01:31:34","TRT02EDTM":"2022-09-11 07:31:34","AP01SDTM":"2019-09-11 13:31:34","AP01EDTM":"2021-09-11 01:31:34","AP02SDTM":"2021-09-11 01:31:34","AP02EDTM":"2022-09-11 07:31:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-10-10","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":12,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.89472,"AVALU":"mg/L","BASE2":9.44889,"BASE":8.89472,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.55417,"PCHG2":-5.86494,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-29 13:31:34","ADY":506,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-72","SUBJID":"id-72","SITEID":"NGA-17","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.40254,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-11 13:31:34","TRTEDTM":"2022-09-11 07:31:34","TRT01SDTM":"2019-09-11 13:31:34","TRT01EDTM":"2021-09-11 01:31:34","TRT02SDTM":"2021-09-11 01:31:34","TRT02EDTM":"2022-09-11 07:31:34","AP01SDTM":"2019-09-11 13:31:34","AP01EDTM":"2021-09-11 01:31:34","AP02SDTM":"2021-09-11 01:31:34","AP02EDTM":"2022-09-11 07:31:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-10-10","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5725,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.58238,"AVALU":"mg/L","BASE2":9.44889,"BASE":8.89472,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.86651,"PCHG2":-9.17049,"CHG":-0.31234,"PCHG":-3.51149,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-23 13:31:34","ADY":620,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-72","SUBJID":"id-72","SITEID":"NGA-17","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.40254,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-11 13:31:34","TRTEDTM":"2022-09-11 07:31:34","TRT01SDTM":"2019-09-11 13:31:34","TRT01EDTM":"2021-09-11 01:31:34","TRT02SDTM":"2021-09-11 01:31:34","TRT02EDTM":"2022-09-11 07:31:34","AP01SDTM":"2019-09-11 13:31:34","AP01EDTM":"2021-09-11 01:31:34","AP02SDTM":"2021-09-11 01:31:34","AP02EDTM":"2022-09-11 07:31:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-10-10","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4877,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.55291,"AVALU":"mg/L","BASE2":9.44889,"BASE":8.89472,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.89598,"PCHG2":-20.06567,"CHG":-1.34181,"PCHG":-15.08548,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-09-05 13:31:34","ADY":725,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-72","SUBJID":"id-72","SITEID":"NGA-17","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.40254,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-11 13:31:34","TRTEDTM":"2022-09-11 07:31:34","TRT01SDTM":"2019-09-11 13:31:34","TRT01EDTM":"2021-09-11 01:31:34","TRT02SDTM":"2021-09-11 01:31:34","TRT02EDTM":"2022-09-11 07:31:34","AP01SDTM":"2019-09-11 13:31:34","AP01EDTM":"2021-09-11 01:31:34","AP02SDTM":"2021-09-11 01:31:34","AP02EDTM":"2022-09-11 07:31:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-10-10","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2774,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.96657,"AVALU":"mg/L","BASE2":9.44889,"BASE":8.89472,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.48232,"PCHG2":-5.10456,"CHG":0.07185,"PCHG":0.80776,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-20 13:31:34","ADY":770,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-72","SUBJID":"id-72","SITEID":"NGA-17","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.40254,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-11 13:31:34","TRTEDTM":"2022-09-11 07:31:34","TRT01SDTM":"2019-09-11 13:31:34","TRT01EDTM":"2021-09-11 01:31:34","TRT02SDTM":"2021-09-11 01:31:34","TRT02EDTM":"2022-09-11 07:31:34","AP01SDTM":"2019-09-11 13:31:34","AP01EDTM":"2021-09-11 01:31:34","AP02SDTM":"2021-09-11 01:31:34","AP02EDTM":"2022-09-11 07:31:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-10-10","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":370,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.23944,"AVALU":"mg/L","BASE2":9.44889,"BASE":8.89472,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.20945,"PCHG2":-23.38318,"CHG":-1.65528,"PCHG":-18.60969,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-02-11 13:31:34","ADY":884,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-72","SUBJID":"id-72","SITEID":"NGA-17","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.40254,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-11 13:31:34","TRTEDTM":"2022-09-11 07:31:34","TRT01SDTM":"2019-09-11 13:31:34","TRT01EDTM":"2021-09-11 01:31:34","TRT02SDTM":"2021-09-11 01:31:34","TRT02EDTM":"2022-09-11 07:31:34","AP01SDTM":"2019-09-11 13:31:34","AP01EDTM":"2021-09-11 01:31:34","AP02SDTM":"2021-09-11 01:31:34","AP02EDTM":"2022-09-11 07:31:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-10-10","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4651,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.07656,"AVALU":"mg/L","BASE2":9.44889,"BASE":8.89472,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.37234,"PCHG2":-3.94054,"CHG":0.18184,"PCHG":2.0443,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-17 13:31:34","ADY":1010,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-72","SUBJID":"id-72","SITEID":"NGA-17","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.40254,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-11 13:31:34","TRTEDTM":"2022-09-11 07:31:34","TRT01SDTM":"2019-09-11 13:31:34","TRT01EDTM":"2021-09-11 01:31:34","TRT02SDTM":"2021-09-11 01:31:34","TRT02EDTM":"2022-09-11 07:31:34","AP01SDTM":"2019-09-11 13:31:34","AP01EDTM":"2021-09-11 01:31:34","AP02SDTM":"2021-09-11 01:31:34","AP02EDTM":"2022-09-11 07:31:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-10-10","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4790,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8496,"AVALU":"g/L","BASE2":2.8496,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-01 13:31:34","ADY":20,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-72","SUBJID":"id-72","SITEID":"NGA-17","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.40254,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-11 13:31:34","TRTEDTM":"2022-09-11 07:31:34","TRT01SDTM":"2019-09-11 13:31:34","TRT01EDTM":"2021-09-11 01:31:34","TRT02SDTM":"2021-09-11 01:31:34","TRT02EDTM":"2022-09-11 07:31:34","AP01SDTM":"2019-09-11 13:31:34","AP01EDTM":"2021-09-11 01:31:34","AP02SDTM":"2021-09-11 01:31:34","AP02EDTM":"2022-09-11 07:31:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-10-10","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2683,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93822,"AVALU":"g/L","BASE2":2.8496,"BASE":2.93822,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.08861,"PCHG2":3.10971,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-29 13:31:34","ADY":506,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-72","SUBJID":"id-72","SITEID":"NGA-17","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.40254,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-11 13:31:34","TRTEDTM":"2022-09-11 07:31:34","TRT01SDTM":"2019-09-11 13:31:34","TRT01EDTM":"2021-09-11 01:31:34","TRT02SDTM":"2021-09-11 01:31:34","TRT02EDTM":"2022-09-11 07:31:34","AP01SDTM":"2019-09-11 13:31:34","AP01EDTM":"2021-09-11 01:31:34","AP02SDTM":"2021-09-11 01:31:34","AP02EDTM":"2022-09-11 07:31:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-10-10","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":623,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91248,"AVALU":"g/L","BASE2":2.8496,"BASE":2.93822,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06288,"PCHG2":2.20663,"CHG":-0.02573,"PCHG":-0.87584,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-23 13:31:34","ADY":620,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-72","SUBJID":"id-72","SITEID":"NGA-17","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.40254,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-11 13:31:34","TRTEDTM":"2022-09-11 07:31:34","TRT01SDTM":"2019-09-11 13:31:34","TRT01EDTM":"2021-09-11 01:31:34","TRT02SDTM":"2021-09-11 01:31:34","TRT02EDTM":"2022-09-11 07:31:34","AP01SDTM":"2019-09-11 13:31:34","AP01EDTM":"2021-09-11 01:31:34","AP02SDTM":"2021-09-11 01:31:34","AP02EDTM":"2022-09-11 07:31:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-10-10","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1823,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89733,"AVALU":"g/L","BASE2":2.8496,"BASE":2.93822,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04773,"PCHG2":1.6748,"CHG":-0.04089,"PCHG":-1.39164,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-05 13:31:34","ADY":725,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-72","SUBJID":"id-72","SITEID":"NGA-17","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.40254,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-11 13:31:34","TRTEDTM":"2022-09-11 07:31:34","TRT01SDTM":"2019-09-11 13:31:34","TRT01EDTM":"2021-09-11 01:31:34","TRT02SDTM":"2021-09-11 01:31:34","TRT02EDTM":"2022-09-11 07:31:34","AP01SDTM":"2019-09-11 13:31:34","AP01EDTM":"2021-09-11 01:31:34","AP02SDTM":"2021-09-11 01:31:34","AP02EDTM":"2022-09-11 07:31:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-10-10","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3068,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.66622,"AVALU":"g/L","BASE2":2.8496,"BASE":2.93822,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18338,"PCHG2":-6.43527,"CHG":-0.27199,"PCHG":-9.25711,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-20 13:31:34","ADY":770,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-72","SUBJID":"id-72","SITEID":"NGA-17","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.40254,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-11 13:31:34","TRTEDTM":"2022-09-11 07:31:34","TRT01SDTM":"2019-09-11 13:31:34","TRT01EDTM":"2021-09-11 01:31:34","TRT02SDTM":"2021-09-11 01:31:34","TRT02EDTM":"2022-09-11 07:31:34","AP01SDTM":"2019-09-11 13:31:34","AP01EDTM":"2021-09-11 01:31:34","AP02SDTM":"2021-09-11 01:31:34","AP02EDTM":"2022-09-11 07:31:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-10-10","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5067,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90838,"AVALU":"g/L","BASE2":2.8496,"BASE":2.93822,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05878,"PCHG2":2.06284,"CHG":-0.02983,"PCHG":-1.01529,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-11 13:31:34","ADY":884,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-17-id-72","SUBJID":"id-72","SITEID":"NGA-17","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-17","INVNAM":"Dr. NGA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":6.40254,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-09","TRTSDTM":"2019-09-11 13:31:34","TRTEDTM":"2022-09-11 07:31:34","TRT01SDTM":"2019-09-11 13:31:34","TRT01EDTM":"2021-09-11 01:31:34","TRT02SDTM":"2021-09-11 01:31:34","TRT02EDTM":"2022-09-11 07:31:34","AP01SDTM":"2019-09-11 13:31:34","AP01EDTM":"2021-09-11 01:31:34","AP02SDTM":"2021-09-11 01:31:34","AP02EDTM":"2022-09-11 07:31:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-11","EOSDY":1096,"LSTALVDT":"2022-10-10","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5366,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87864,"AVALU":"g/L","BASE2":2.8496,"BASE":2.93822,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02904,"PCHG2":1.01906,"CHG":-0.05958,"PCHG":-2.02759,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-17 13:31:34","ADY":1010,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-308","SUBJID":"id-308","SITEID":"NGA-2","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":4.824,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-22","TRTSDTM":"2019-09-25 10:44:03","TRT01SDTM":"2019-09-25 10:44:03","AP01SDTM":"2019-09-25 10:44:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1528,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.45415,"AVALU":"U/L","BASE2":11.45415,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-30 10:44:03","ADY":5,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-308","SUBJID":"id-308","SITEID":"NGA-2","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":4.824,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-22","TRTSDTM":"2019-09-25 10:44:03","TRT01SDTM":"2019-09-25 10:44:03","AP01SDTM":"2019-09-25 10:44:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7723,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.67573,"AVALU":"U/L","BASE2":11.45415,"BASE":33.67573,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":22.22158,"PCHG2":194.00453,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-13 10:44:03","ADY":18,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-308","SUBJID":"id-308","SITEID":"NGA-2","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":4.824,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-22","TRTSDTM":"2019-09-25 10:44:03","TRT01SDTM":"2019-09-25 10:44:03","AP01SDTM":"2019-09-25 10:44:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":512,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.02612,"AVALU":"U/L","BASE2":11.45415,"BASE":33.67573,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.57197,"PCHG2":4.99357,"CHG":-21.64961,"PCHG":-64.28845,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-09 10:44:03","ADY":75,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-308","SUBJID":"id-308","SITEID":"NGA-2","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":4.824,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-22","TRTSDTM":"2019-09-25 10:44:03","TRT01SDTM":"2019-09-25 10:44:03","AP01SDTM":"2019-09-25 10:44:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4906,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.16391,"AVALU":"U/L","BASE2":11.45415,"BASE":33.67573,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.70976,"PCHG2":76.04016,"CHG":-13.51182,"PCHG":-40.12332,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-18 10:44:03","ADY":115,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-308","SUBJID":"id-308","SITEID":"NGA-2","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":4.824,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-22","TRTSDTM":"2019-09-25 10:44:03","TRT01SDTM":"2019-09-25 10:44:03","AP01SDTM":"2019-09-25 10:44:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6225,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.62889,"AVALU":"U/L","BASE2":11.45415,"BASE":33.67573,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.17474,"PCHG2":53.90831,"CHG":-16.04684,"PCHG":-47.65104,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-28 10:44:03","ADY":216,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-308","SUBJID":"id-308","SITEID":"NGA-2","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":4.824,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-22","TRTSDTM":"2019-09-25 10:44:03","TRT01SDTM":"2019-09-25 10:44:03","AP01SDTM":"2019-09-25 10:44:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5455,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.39734,"AVALU":"U/L","BASE2":11.45415,"BASE":33.67573,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.94319,"PCHG2":34.42582,"CHG":-18.27839,"PCHG":-54.27764,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-23 10:44:03","ADY":394,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-308","SUBJID":"id-308","SITEID":"NGA-2","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":4.824,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-22","TRTSDTM":"2019-09-25 10:44:03","TRT01SDTM":"2019-09-25 10:44:03","AP01SDTM":"2019-09-25 10:44:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3500,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.38113,"AVALU":"U/L","BASE2":11.45415,"BASE":33.67573,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.92697,"PCHG2":86.66701,"CHG":-12.2946,"PCHG":-36.5088,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-04 10:44:03","ADY":467,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-308","SUBJID":"id-308","SITEID":"NGA-2","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":4.824,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-22","TRTSDTM":"2019-09-25 10:44:03","TRT01SDTM":"2019-09-25 10:44:03","AP01SDTM":"2019-09-25 10:44:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1393,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.18982,"AVALU":"mg/L","BASE2":8.18982,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-4","ADTM":"2019-09-30 10:44:03","ADY":5,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-308","SUBJID":"id-308","SITEID":"NGA-2","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":4.824,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-22","TRTSDTM":"2019-09-25 10:44:03","TRT01SDTM":"2019-09-25 10:44:03","AP01SDTM":"2019-09-25 10:44:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4813,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.9298,"AVALU":"mg/L","BASE2":8.18982,"BASE":7.9298,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.26002,"PCHG2":-3.17494,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-4","BTOXGR":"-4","ADTM":"2019-10-13 10:44:03","ADY":18,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-308","SUBJID":"id-308","SITEID":"NGA-2","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":4.824,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-22","TRTSDTM":"2019-09-25 10:44:03","TRT01SDTM":"2019-09-25 10:44:03","AP01SDTM":"2019-09-25 10:44:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3156,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.2678,"AVALU":"mg/L","BASE2":8.18982,"BASE":7.9298,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.07798,"PCHG2":25.37275,"CHG":2.338,"PCHG":29.48378,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"2","BTOXGR":"-4","ADTM":"2019-12-09 10:44:03","ADY":75,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-308","SUBJID":"id-308","SITEID":"NGA-2","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":4.824,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-22","TRTSDTM":"2019-09-25 10:44:03","TRT01SDTM":"2019-09-25 10:44:03","AP01SDTM":"2019-09-25 10:44:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2352,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.75595,"AVALU":"mg/L","BASE2":8.18982,"BASE":7.9298,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.56613,"PCHG2":19.12286,"CHG":1.82615,"PCHG":23.02896,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2020-01-18 10:44:03","ADY":115,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-308","SUBJID":"id-308","SITEID":"NGA-2","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":4.824,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-22","TRTSDTM":"2019-09-25 10:44:03","TRT01SDTM":"2019-09-25 10:44:03","AP01SDTM":"2019-09-25 10:44:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1887,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.83675,"AVALU":"mg/L","BASE2":8.18982,"BASE":7.9298,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.64693,"PCHG2":20.10942,"CHG":1.90695,"PCHG":24.04786,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2020-04-28 10:44:03","ADY":216,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-308","SUBJID":"id-308","SITEID":"NGA-2","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":4.824,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-22","TRTSDTM":"2019-09-25 10:44:03","TRT01SDTM":"2019-09-25 10:44:03","AP01SDTM":"2019-09-25 10:44:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7200,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.26557,"AVALU":"mg/L","BASE2":8.18982,"BASE":7.9298,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07574,"PCHG2":0.92486,"CHG":0.33577,"PCHG":4.23423,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2020-10-23 10:44:03","ADY":394,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-308","SUBJID":"id-308","SITEID":"NGA-2","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":4.824,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-22","TRTSDTM":"2019-09-25 10:44:03","TRT01SDTM":"2019-09-25 10:44:03","AP01SDTM":"2019-09-25 10:44:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7935,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.12091,"AVALU":"mg/L","BASE2":8.18982,"BASE":7.9298,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.93109,"PCHG2":11.36889,"CHG":1.19111,"PCHG":15.02073,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-01-04 10:44:03","ADY":467,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-308","SUBJID":"id-308","SITEID":"NGA-2","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":4.824,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-22","TRTSDTM":"2019-09-25 10:44:03","TRT01SDTM":"2019-09-25 10:44:03","AP01SDTM":"2019-09-25 10:44:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3381,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.69001,"AVALU":"g/L","BASE2":2.69001,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-30 10:44:03","ADY":5,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-308","SUBJID":"id-308","SITEID":"NGA-2","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":4.824,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-22","TRTSDTM":"2019-09-25 10:44:03","TRT01SDTM":"2019-09-25 10:44:03","AP01SDTM":"2019-09-25 10:44:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7757,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93004,"AVALU":"g/L","BASE2":2.69001,"BASE":2.93004,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.24003,"PCHG2":8.92306,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-13 10:44:03","ADY":18,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-308","SUBJID":"id-308","SITEID":"NGA-2","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":4.824,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-22","TRTSDTM":"2019-09-25 10:44:03","TRT01SDTM":"2019-09-25 10:44:03","AP01SDTM":"2019-09-25 10:44:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2659,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82321,"AVALU":"g/L","BASE2":2.69001,"BASE":2.93004,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1332,"PCHG2":4.95178,"CHG":-0.10683,"PCHG":-3.64596,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-09 10:44:03","ADY":75,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-308","SUBJID":"id-308","SITEID":"NGA-2","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":4.824,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-22","TRTSDTM":"2019-09-25 10:44:03","TRT01SDTM":"2019-09-25 10:44:03","AP01SDTM":"2019-09-25 10:44:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7800,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91974,"AVALU":"g/L","BASE2":2.69001,"BASE":2.93004,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.22973,"PCHG2":8.54014,"CHG":-0.0103,"PCHG":-0.35155,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-18 10:44:03","ADY":115,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-308","SUBJID":"id-308","SITEID":"NGA-2","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":4.824,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-22","TRTSDTM":"2019-09-25 10:44:03","TRT01SDTM":"2019-09-25 10:44:03","AP01SDTM":"2019-09-25 10:44:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1280,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92286,"AVALU":"g/L","BASE2":2.69001,"BASE":2.93004,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.23286,"PCHG2":8.65635,"CHG":-0.00717,"PCHG":-0.24486,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-28 10:44:03","ADY":216,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-308","SUBJID":"id-308","SITEID":"NGA-2","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":4.824,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-22","TRTSDTM":"2019-09-25 10:44:03","TRT01SDTM":"2019-09-25 10:44:03","AP01SDTM":"2019-09-25 10:44:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7020,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85605,"AVALU":"g/L","BASE2":2.69001,"BASE":2.93004,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16605,"PCHG2":6.17271,"CHG":-0.07398,"PCHG":-2.52504,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-23 10:44:03","ADY":394,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-308","SUBJID":"id-308","SITEID":"NGA-2","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":4.824,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-22","TRTSDTM":"2019-09-25 10:44:03","TRT01SDTM":"2019-09-25 10:44:03","AP01SDTM":"2019-09-25 10:44:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2358,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01632,"AVALU":"g/L","BASE2":2.69001,"BASE":2.93004,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.32631,"PCHG2":12.13045,"CHG":0.08628,"PCHG":2.94463,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-01-04 10:44:03","ADY":467,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-353","SUBJID":"id-353","SITEID":"NGA-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.94481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-02 21:26:47","TRTEDTM":"2023-03-03 15:26:47","TRT01SDTM":"2020-03-02 21:26:47","TRT01EDTM":"2022-03-03 09:26:47","TRT02SDTM":"2022-03-03 09:26:47","TRT02EDTM":"2023-03-03 15:26:47","AP01SDTM":"2020-03-02 21:26:47","AP01EDTM":"2022-03-03 09:26:47","AP02SDTM":"2022-03-03 09:26:47","AP02EDTM":"2023-03-03 15:26:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6219,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.35624,"AVALU":"U/L","BASE2":16.35624,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-22 21:26:47","ADY":112,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-353","SUBJID":"id-353","SITEID":"NGA-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.94481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-02 21:26:47","TRTEDTM":"2023-03-03 15:26:47","TRT01SDTM":"2020-03-02 21:26:47","TRT01EDTM":"2022-03-03 09:26:47","TRT02SDTM":"2022-03-03 09:26:47","TRT02EDTM":"2023-03-03 15:26:47","AP01SDTM":"2020-03-02 21:26:47","AP01EDTM":"2022-03-03 09:26:47","AP02SDTM":"2022-03-03 09:26:47","AP02EDTM":"2023-03-03 15:26:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5345,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.84279,"AVALU":"U/L","BASE2":16.35624,"BASE":28.84279,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":12.48655,"PCHG2":76.34118,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-22 21:26:47","ADY":142,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-353","SUBJID":"id-353","SITEID":"NGA-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.94481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-02 21:26:47","TRTEDTM":"2023-03-03 15:26:47","TRT01SDTM":"2020-03-02 21:26:47","TRT01EDTM":"2022-03-03 09:26:47","TRT02SDTM":"2022-03-03 09:26:47","TRT02EDTM":"2023-03-03 15:26:47","AP01SDTM":"2020-03-02 21:26:47","AP01EDTM":"2022-03-03 09:26:47","AP02SDTM":"2022-03-03 09:26:47","AP02EDTM":"2023-03-03 15:26:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2624,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.60334,"AVALU":"U/L","BASE2":16.35624,"BASE":28.84279,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.2471,"PCHG2":1.51072,"CHG":-12.23945,"PCHG":-42.43505,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-29 21:26:47","ADY":149,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-353","SUBJID":"id-353","SITEID":"NGA-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.94481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-02 21:26:47","TRTEDTM":"2023-03-03 15:26:47","TRT01SDTM":"2020-03-02 21:26:47","TRT01EDTM":"2022-03-03 09:26:47","TRT02SDTM":"2022-03-03 09:26:47","TRT02EDTM":"2023-03-03 15:26:47","AP01SDTM":"2020-03-02 21:26:47","AP01EDTM":"2022-03-03 09:26:47","AP02SDTM":"2022-03-03 09:26:47","AP02EDTM":"2023-03-03 15:26:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3795,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.49802,"AVALU":"U/L","BASE2":16.35624,"BASE":28.84279,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.85822,"PCHG2":-54.15805,"CHG":-21.34477,"PCHG":-74.00383,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-18 21:26:47","ADY":291,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-353","SUBJID":"id-353","SITEID":"NGA-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.94481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-02 21:26:47","TRTEDTM":"2023-03-03 15:26:47","TRT01SDTM":"2020-03-02 21:26:47","TRT01EDTM":"2022-03-03 09:26:47","TRT02SDTM":"2022-03-03 09:26:47","TRT02EDTM":"2023-03-03 15:26:47","AP01SDTM":"2020-03-02 21:26:47","AP01EDTM":"2022-03-03 09:26:47","AP02SDTM":"2022-03-03 09:26:47","AP02EDTM":"2023-03-03 15:26:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5444,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.92325,"AVALU":"U/L","BASE2":16.35624,"BASE":28.84279,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.43299,"PCHG2":-39.3305,"CHG":-18.91954,"PCHG":-65.59539,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-13 21:26:47","ADY":437,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-353","SUBJID":"id-353","SITEID":"NGA-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.94481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-02 21:26:47","TRTEDTM":"2023-03-03 15:26:47","TRT01SDTM":"2020-03-02 21:26:47","TRT01EDTM":"2022-03-03 09:26:47","TRT02SDTM":"2022-03-03 09:26:47","TRT02EDTM":"2023-03-03 15:26:47","AP01SDTM":"2020-03-02 21:26:47","AP01EDTM":"2022-03-03 09:26:47","AP02SDTM":"2022-03-03 09:26:47","AP02EDTM":"2023-03-03 15:26:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3202,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.47272,"AVALU":"U/L","BASE2":16.35624,"BASE":28.84279,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.11648,"PCHG2":6.826,"CHG":-11.37007,"PCHG":-39.42084,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-25 21:26:47","ADY":967,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-353","SUBJID":"id-353","SITEID":"NGA-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.94481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-02 21:26:47","TRTEDTM":"2023-03-03 15:26:47","TRT01SDTM":"2020-03-02 21:26:47","TRT01EDTM":"2022-03-03 09:26:47","TRT02SDTM":"2022-03-03 09:26:47","TRT02EDTM":"2023-03-03 15:26:47","AP01SDTM":"2020-03-02 21:26:47","AP01EDTM":"2022-03-03 09:26:47","AP02SDTM":"2022-03-03 09:26:47","AP02EDTM":"2023-03-03 15:26:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3295,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.16467,"AVALU":"U/L","BASE2":16.35624,"BASE":28.84279,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.19157,"PCHG2":-50.08224,"CHG":-20.67812,"PCHG":-71.69251,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-08 21:26:47","ADY":1011,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-353","SUBJID":"id-353","SITEID":"NGA-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.94481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-02 21:26:47","TRTEDTM":"2023-03-03 15:26:47","TRT01SDTM":"2020-03-02 21:26:47","TRT01EDTM":"2022-03-03 09:26:47","TRT02SDTM":"2022-03-03 09:26:47","TRT02EDTM":"2023-03-03 15:26:47","AP01SDTM":"2020-03-02 21:26:47","AP01EDTM":"2022-03-03 09:26:47","AP02SDTM":"2022-03-03 09:26:47","AP02EDTM":"2023-03-03 15:26:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3715,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.45023,"AVALU":"mg/L","BASE2":9.45023,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-06-22 21:26:47","ADY":112,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-353","SUBJID":"id-353","SITEID":"NGA-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.94481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-02 21:26:47","TRTEDTM":"2023-03-03 15:26:47","TRT01SDTM":"2020-03-02 21:26:47","TRT01EDTM":"2022-03-03 09:26:47","TRT02SDTM":"2022-03-03 09:26:47","TRT02EDTM":"2023-03-03 15:26:47","AP01SDTM":"2020-03-02 21:26:47","AP01EDTM":"2022-03-03 09:26:47","AP02SDTM":"2022-03-03 09:26:47","AP02EDTM":"2023-03-03 15:26:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6928,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.34663,"AVALU":"mg/L","BASE2":9.45023,"BASE":11.34663,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.8964,"PCHG2":20.06721,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-07-22 21:26:47","ADY":142,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-353","SUBJID":"id-353","SITEID":"NGA-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.94481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-02 21:26:47","TRTEDTM":"2023-03-03 15:26:47","TRT01SDTM":"2020-03-02 21:26:47","TRT01EDTM":"2022-03-03 09:26:47","TRT02SDTM":"2022-03-03 09:26:47","TRT02EDTM":"2023-03-03 15:26:47","AP01SDTM":"2020-03-02 21:26:47","AP01EDTM":"2022-03-03 09:26:47","AP02SDTM":"2022-03-03 09:26:47","AP02EDTM":"2023-03-03 15:26:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2186,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.64382,"AVALU":"mg/L","BASE2":9.45023,"BASE":11.34663,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.80641,"PCHG2":-8.53324,"CHG":-2.70281,"PCHG":-23.82037,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-07-29 21:26:47","ADY":149,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-353","SUBJID":"id-353","SITEID":"NGA-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.94481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-02 21:26:47","TRTEDTM":"2023-03-03 15:26:47","TRT01SDTM":"2020-03-02 21:26:47","TRT01EDTM":"2022-03-03 09:26:47","TRT02SDTM":"2022-03-03 09:26:47","TRT02EDTM":"2023-03-03 15:26:47","AP01SDTM":"2020-03-02 21:26:47","AP01EDTM":"2022-03-03 09:26:47","AP02SDTM":"2022-03-03 09:26:47","AP02EDTM":"2023-03-03 15:26:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2276,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.08723,"AVALU":"mg/L","BASE2":9.45023,"BASE":11.34663,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.36301,"PCHG2":-14.42298,"CHG":-3.2594,"PCHG":-28.72574,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-12-18 21:26:47","ADY":291,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-353","SUBJID":"id-353","SITEID":"NGA-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.94481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-02 21:26:47","TRTEDTM":"2023-03-03 15:26:47","TRT01SDTM":"2020-03-02 21:26:47","TRT01EDTM":"2022-03-03 09:26:47","TRT02SDTM":"2022-03-03 09:26:47","TRT02EDTM":"2023-03-03 15:26:47","AP01SDTM":"2020-03-02 21:26:47","AP01EDTM":"2022-03-03 09:26:47","AP02SDTM":"2022-03-03 09:26:47","AP02EDTM":"2023-03-03 15:26:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4194,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.51835,"AVALU":"mg/L","BASE2":9.45023,"BASE":11.34663,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.93189,"PCHG2":-9.86098,"CHG":-2.82828,"PCHG":-24.9262,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-05-13 21:26:47","ADY":437,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-353","SUBJID":"id-353","SITEID":"NGA-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.94481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-02 21:26:47","TRTEDTM":"2023-03-03 15:26:47","TRT01SDTM":"2020-03-02 21:26:47","TRT01EDTM":"2022-03-03 09:26:47","TRT02SDTM":"2022-03-03 09:26:47","TRT02EDTM":"2023-03-03 15:26:47","AP01SDTM":"2020-03-02 21:26:47","AP01EDTM":"2022-03-03 09:26:47","AP02SDTM":"2022-03-03 09:26:47","AP02EDTM":"2023-03-03 15:26:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3400,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.6197,"AVALU":"mg/L","BASE2":9.45023,"BASE":11.34663,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.83053,"PCHG2":-8.78849,"CHG":-2.72693,"PCHG":-24.03295,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2022-10-25 21:26:47","ADY":967,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-353","SUBJID":"id-353","SITEID":"NGA-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.94481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-02 21:26:47","TRTEDTM":"2023-03-03 15:26:47","TRT01SDTM":"2020-03-02 21:26:47","TRT01EDTM":"2022-03-03 09:26:47","TRT02SDTM":"2022-03-03 09:26:47","TRT02EDTM":"2023-03-03 15:26:47","AP01SDTM":"2020-03-02 21:26:47","AP01EDTM":"2022-03-03 09:26:47","AP02SDTM":"2022-03-03 09:26:47","AP02EDTM":"2023-03-03 15:26:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":648,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.19394,"AVALU":"mg/L","BASE2":9.45023,"BASE":11.34663,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.25629,"PCHG2":-23.87551,"CHG":-4.15269,"PCHG":-36.59844,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-3","BTOXGR":"1","ADTM":"2022-12-08 21:26:47","ADY":1011,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-353","SUBJID":"id-353","SITEID":"NGA-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.94481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-02 21:26:47","TRTEDTM":"2023-03-03 15:26:47","TRT01SDTM":"2020-03-02 21:26:47","TRT01EDTM":"2022-03-03 09:26:47","TRT02SDTM":"2022-03-03 09:26:47","TRT02EDTM":"2023-03-03 15:26:47","AP01SDTM":"2020-03-02 21:26:47","AP01EDTM":"2022-03-03 09:26:47","AP02SDTM":"2022-03-03 09:26:47","AP02EDTM":"2023-03-03 15:26:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2522,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90286,"AVALU":"g/L","BASE2":2.90286,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-22 21:26:47","ADY":112,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-353","SUBJID":"id-353","SITEID":"NGA-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.94481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-02 21:26:47","TRTEDTM":"2023-03-03 15:26:47","TRT01SDTM":"2020-03-02 21:26:47","TRT01EDTM":"2022-03-03 09:26:47","TRT02SDTM":"2022-03-03 09:26:47","TRT02EDTM":"2023-03-03 15:26:47","AP01SDTM":"2020-03-02 21:26:47","AP01EDTM":"2022-03-03 09:26:47","AP02SDTM":"2022-03-03 09:26:47","AP02EDTM":"2023-03-03 15:26:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3491,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94283,"AVALU":"g/L","BASE2":2.90286,"BASE":2.94283,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.03997,"PCHG2":1.37696,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-22 21:26:47","ADY":142,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-353","SUBJID":"id-353","SITEID":"NGA-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.94481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-02 21:26:47","TRTEDTM":"2023-03-03 15:26:47","TRT01SDTM":"2020-03-02 21:26:47","TRT01EDTM":"2022-03-03 09:26:47","TRT02SDTM":"2022-03-03 09:26:47","TRT02EDTM":"2023-03-03 15:26:47","AP01SDTM":"2020-03-02 21:26:47","AP01EDTM":"2022-03-03 09:26:47","AP02SDTM":"2022-03-03 09:26:47","AP02EDTM":"2023-03-03 15:26:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2188,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.06883,"AVALU":"g/L","BASE2":2.90286,"BASE":2.94283,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16597,"PCHG2":5.71761,"CHG":0.126,"PCHG":4.2817,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-07-29 21:26:47","ADY":149,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-353","SUBJID":"id-353","SITEID":"NGA-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.94481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-02 21:26:47","TRTEDTM":"2023-03-03 15:26:47","TRT01SDTM":"2020-03-02 21:26:47","TRT01EDTM":"2022-03-03 09:26:47","TRT02SDTM":"2022-03-03 09:26:47","TRT02EDTM":"2023-03-03 15:26:47","AP01SDTM":"2020-03-02 21:26:47","AP01EDTM":"2022-03-03 09:26:47","AP02SDTM":"2022-03-03 09:26:47","AP02EDTM":"2023-03-03 15:26:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2653,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90338,"AVALU":"g/L","BASE2":2.90286,"BASE":2.94283,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00052,"PCHG2":0.01786,"CHG":-0.03945,"PCHG":-1.34064,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-18 21:26:47","ADY":291,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-353","SUBJID":"id-353","SITEID":"NGA-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.94481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-02 21:26:47","TRTEDTM":"2023-03-03 15:26:47","TRT01SDTM":"2020-03-02 21:26:47","TRT01EDTM":"2022-03-03 09:26:47","TRT02SDTM":"2022-03-03 09:26:47","TRT02EDTM":"2023-03-03 15:26:47","AP01SDTM":"2020-03-02 21:26:47","AP01EDTM":"2022-03-03 09:26:47","AP02SDTM":"2022-03-03 09:26:47","AP02EDTM":"2023-03-03 15:26:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8226,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83553,"AVALU":"g/L","BASE2":2.90286,"BASE":2.94283,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06733,"PCHG2":-2.31945,"CHG":-0.1073,"PCHG":-3.6462,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-13 21:26:47","ADY":437,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-353","SUBJID":"id-353","SITEID":"NGA-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.94481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-02 21:26:47","TRTEDTM":"2023-03-03 15:26:47","TRT01SDTM":"2020-03-02 21:26:47","TRT01EDTM":"2022-03-03 09:26:47","TRT02SDTM":"2022-03-03 09:26:47","TRT02EDTM":"2023-03-03 15:26:47","AP01SDTM":"2020-03-02 21:26:47","AP01EDTM":"2022-03-03 09:26:47","AP02SDTM":"2022-03-03 09:26:47","AP02EDTM":"2023-03-03 15:26:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1684,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81103,"AVALU":"g/L","BASE2":2.90286,"BASE":2.94283,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09183,"PCHG2":-3.16346,"CHG":-0.1318,"PCHG":-4.47875,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-25 21:26:47","ADY":967,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-2-id-353","SUBJID":"id-353","SITEID":"NGA-2","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-2","INVNAM":"Dr. NGA-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Africa","STRATA1":"B","STRATA2":"S1","BMRKR1":3.94481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-02-28","TRTSDTM":"2020-03-02 21:26:47","TRTEDTM":"2023-03-03 15:26:47","TRT01SDTM":"2020-03-02 21:26:47","TRT01EDTM":"2022-03-03 09:26:47","TRT02SDTM":"2022-03-03 09:26:47","TRT02EDTM":"2023-03-03 15:26:47","AP01SDTM":"2020-03-02 21:26:47","AP01EDTM":"2022-03-03 09:26:47","AP02SDTM":"2022-03-03 09:26:47","AP02EDTM":"2023-03-03 15:26:47","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-03","EOSDY":1096,"LSTALVDT":"2023-04-01","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2581,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.08455,"AVALU":"g/L","BASE2":2.90286,"BASE":2.94283,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18169,"PCHG2":6.25898,"CHG":0.14172,"PCHG":4.81571,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-12-08 21:26:47","ADY":1011,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-215","SUBJID":"id-215","SITEID":"NGA-4","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":10.49773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-15","TRTSDTM":"2020-05-19 00:04:12","TRTEDTM":"2022-02-18 10:40:54","TRT01SDTM":"2020-05-19 00:04:12","TRT01EDTM":"2021-02-18 04:40:54","TRT02SDTM":"2021-02-18 04:40:54","TRT02EDTM":"2022-02-18 10:40:54","AP01SDTM":"2020-05-19 00:04:12","AP01EDTM":"2021-02-18 04:40:54","AP02SDTM":"2021-02-18 04:40:54","AP02EDTM":"2022-02-18 10:40:54","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":641,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":647,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4157,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.46228,"AVALU":"U/L","BASE2":29.46228,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-31 00:04:12","ADY":12,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-215","SUBJID":"id-215","SITEID":"NGA-4","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":10.49773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-15","TRTSDTM":"2020-05-19 00:04:12","TRTEDTM":"2022-02-18 10:40:54","TRT01SDTM":"2020-05-19 00:04:12","TRT01EDTM":"2021-02-18 04:40:54","TRT02SDTM":"2021-02-18 04:40:54","TRT02EDTM":"2022-02-18 10:40:54","AP01SDTM":"2020-05-19 00:04:12","AP01EDTM":"2021-02-18 04:40:54","AP02SDTM":"2021-02-18 04:40:54","AP02EDTM":"2022-02-18 10:40:54","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":641,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":647,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3207,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.64743,"AVALU":"U/L","BASE2":29.46228,"BASE":12.64743,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-16.81485,"PCHG2":-57.07246,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-21 00:04:12","ADY":63,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-215","SUBJID":"id-215","SITEID":"NGA-4","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":10.49773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-15","TRTSDTM":"2020-05-19 00:04:12","TRTEDTM":"2022-02-18 10:40:54","TRT01SDTM":"2020-05-19 00:04:12","TRT01EDTM":"2021-02-18 04:40:54","TRT02SDTM":"2021-02-18 04:40:54","TRT02EDTM":"2022-02-18 10:40:54","AP01SDTM":"2020-05-19 00:04:12","AP01EDTM":"2021-02-18 04:40:54","AP02SDTM":"2021-02-18 04:40:54","AP02EDTM":"2022-02-18 10:40:54","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":641,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":647,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5862,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.15802,"AVALU":"U/L","BASE2":29.46228,"BASE":12.64743,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.30427,"PCHG2":-31.58027,"CHG":7.51058,"PCHG":59.38425,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-14 00:04:12","ADY":118,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-215","SUBJID":"id-215","SITEID":"NGA-4","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":10.49773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-15","TRTSDTM":"2020-05-19 00:04:12","TRTEDTM":"2022-02-18 10:40:54","TRT01SDTM":"2020-05-19 00:04:12","TRT01EDTM":"2021-02-18 04:40:54","TRT02SDTM":"2021-02-18 04:40:54","TRT02EDTM":"2022-02-18 10:40:54","AP01SDTM":"2020-05-19 00:04:12","AP01EDTM":"2021-02-18 04:40:54","AP02SDTM":"2021-02-18 04:40:54","AP02EDTM":"2022-02-18 10:40:54","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":641,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":647,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":446,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.95733,"AVALU":"U/L","BASE2":29.46228,"BASE":12.64743,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-19.50496,"PCHG2":-66.20314,"CHG":-2.69011,"PCHG":-21.26998,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-04 00:04:12","ADY":138,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-215","SUBJID":"id-215","SITEID":"NGA-4","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":10.49773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-15","TRTSDTM":"2020-05-19 00:04:12","TRTEDTM":"2022-02-18 10:40:54","TRT01SDTM":"2020-05-19 00:04:12","TRT01EDTM":"2021-02-18 04:40:54","TRT02SDTM":"2021-02-18 04:40:54","TRT02EDTM":"2022-02-18 10:40:54","AP01SDTM":"2020-05-19 00:04:12","AP01EDTM":"2021-02-18 04:40:54","AP02SDTM":"2021-02-18 04:40:54","AP02EDTM":"2022-02-18 10:40:54","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":641,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":647,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3506,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.56396,"AVALU":"U/L","BASE2":29.46228,"BASE":12.64743,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.89832,"PCHG2":-9.8374,"CHG":13.91653,"PCHG":110.03441,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-31 00:04:12","ADY":165,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-215","SUBJID":"id-215","SITEID":"NGA-4","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":10.49773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-15","TRTSDTM":"2020-05-19 00:04:12","TRTEDTM":"2022-02-18 10:40:54","TRT01SDTM":"2020-05-19 00:04:12","TRT01EDTM":"2021-02-18 04:40:54","TRT02SDTM":"2021-02-18 04:40:54","TRT02EDTM":"2022-02-18 10:40:54","AP01SDTM":"2020-05-19 00:04:12","AP01EDTM":"2021-02-18 04:40:54","AP02SDTM":"2021-02-18 04:40:54","AP02EDTM":"2022-02-18 10:40:54","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":641,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":647,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":738,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.374,"AVALU":"U/L","BASE2":29.46228,"BASE":12.64743,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.08828,"PCHG2":-34.24135,"CHG":6.72657,"PCHG":53.18523,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-26 00:04:12","ADY":221,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-215","SUBJID":"id-215","SITEID":"NGA-4","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":10.49773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-15","TRTSDTM":"2020-05-19 00:04:12","TRTEDTM":"2022-02-18 10:40:54","TRT01SDTM":"2020-05-19 00:04:12","TRT01EDTM":"2021-02-18 04:40:54","TRT02SDTM":"2021-02-18 04:40:54","TRT02EDTM":"2022-02-18 10:40:54","AP01SDTM":"2020-05-19 00:04:12","AP01EDTM":"2021-02-18 04:40:54","AP02SDTM":"2021-02-18 04:40:54","AP02EDTM":"2022-02-18 10:40:54","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":641,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":647,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2328,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.88747,"AVALU":"U/L","BASE2":29.46228,"BASE":12.64743,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.57481,"PCHG2":-1.95101,"CHG":16.24004,"PCHG":128.4058,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-28 00:04:12","ADY":619,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-215","SUBJID":"id-215","SITEID":"NGA-4","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":10.49773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-15","TRTSDTM":"2020-05-19 00:04:12","TRTEDTM":"2022-02-18 10:40:54","TRT01SDTM":"2020-05-19 00:04:12","TRT01EDTM":"2021-02-18 04:40:54","TRT02SDTM":"2021-02-18 04:40:54","TRT02EDTM":"2022-02-18 10:40:54","AP01SDTM":"2020-05-19 00:04:12","AP01EDTM":"2021-02-18 04:40:54","AP02SDTM":"2021-02-18 04:40:54","AP02EDTM":"2022-02-18 10:40:54","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":641,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":647,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3061,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.29138,"AVALU":"mg/L","BASE2":7.29138,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-1","ADTM":"2020-05-31 00:04:12","ADY":12,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-215","SUBJID":"id-215","SITEID":"NGA-4","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":10.49773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-15","TRTSDTM":"2020-05-19 00:04:12","TRTEDTM":"2022-02-18 10:40:54","TRT01SDTM":"2020-05-19 00:04:12","TRT01EDTM":"2021-02-18 04:40:54","TRT02SDTM":"2021-02-18 04:40:54","TRT02EDTM":"2022-02-18 10:40:54","AP01SDTM":"2020-05-19 00:04:12","AP01EDTM":"2021-02-18 04:40:54","AP02SDTM":"2021-02-18 04:40:54","AP02EDTM":"2022-02-18 10:40:54","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":641,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":647,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4824,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.86032,"AVALU":"mg/L","BASE2":7.29138,"BASE":7.86032,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.56894,"PCHG2":7.80285,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2020-07-21 00:04:12","ADY":63,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-215","SUBJID":"id-215","SITEID":"NGA-4","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":10.49773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-15","TRTSDTM":"2020-05-19 00:04:12","TRTEDTM":"2022-02-18 10:40:54","TRT01SDTM":"2020-05-19 00:04:12","TRT01EDTM":"2021-02-18 04:40:54","TRT02SDTM":"2021-02-18 04:40:54","TRT02EDTM":"2022-02-18 10:40:54","AP01SDTM":"2020-05-19 00:04:12","AP01EDTM":"2021-02-18 04:40:54","AP02SDTM":"2021-02-18 04:40:54","AP02EDTM":"2022-02-18 10:40:54","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":641,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":647,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7928,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.60102,"AVALU":"mg/L","BASE2":7.29138,"BASE":7.86032,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.30964,"PCHG2":4.24664,"CHG":-0.2593,"PCHG":-3.2988,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-4","BTOXGR":"-1","ADTM":"2020-09-14 00:04:12","ADY":118,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-215","SUBJID":"id-215","SITEID":"NGA-4","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":10.49773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-15","TRTSDTM":"2020-05-19 00:04:12","TRTEDTM":"2022-02-18 10:40:54","TRT01SDTM":"2020-05-19 00:04:12","TRT01EDTM":"2021-02-18 04:40:54","TRT02SDTM":"2021-02-18 04:40:54","TRT02EDTM":"2022-02-18 10:40:54","AP01SDTM":"2020-05-19 00:04:12","AP01EDTM":"2021-02-18 04:40:54","AP02SDTM":"2021-02-18 04:40:54","AP02EDTM":"2022-02-18 10:40:54","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":641,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":647,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2067,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.96578,"AVALU":"mg/L","BASE2":7.29138,"BASE":7.86032,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.67439,"PCHG2":50.39364,"CHG":3.10546,"PCHG":39.50804,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"3","BTOXGR":"-1","ADTM":"2020-10-04 00:04:12","ADY":138,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-215","SUBJID":"id-215","SITEID":"NGA-4","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":10.49773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-15","TRTSDTM":"2020-05-19 00:04:12","TRTEDTM":"2022-02-18 10:40:54","TRT01SDTM":"2020-05-19 00:04:12","TRT01EDTM":"2021-02-18 04:40:54","TRT02SDTM":"2021-02-18 04:40:54","TRT02EDTM":"2022-02-18 10:40:54","AP01SDTM":"2020-05-19 00:04:12","AP01EDTM":"2021-02-18 04:40:54","AP02SDTM":"2021-02-18 04:40:54","AP02EDTM":"2022-02-18 10:40:54","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":641,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":647,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5837,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.61436,"AVALU":"mg/L","BASE2":7.29138,"BASE":7.86032,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.32298,"PCHG2":31.85926,"CHG":1.75405,"PCHG":22.31519,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-10-31 00:04:12","ADY":165,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-215","SUBJID":"id-215","SITEID":"NGA-4","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":10.49773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-15","TRTSDTM":"2020-05-19 00:04:12","TRTEDTM":"2022-02-18 10:40:54","TRT01SDTM":"2020-05-19 00:04:12","TRT01EDTM":"2021-02-18 04:40:54","TRT02SDTM":"2021-02-18 04:40:54","TRT02EDTM":"2022-02-18 10:40:54","AP01SDTM":"2020-05-19 00:04:12","AP01EDTM":"2021-02-18 04:40:54","AP02SDTM":"2021-02-18 04:40:54","AP02EDTM":"2022-02-18 10:40:54","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":641,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":647,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1142,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.34186,"AVALU":"mg/L","BASE2":7.29138,"BASE":7.86032,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.05048,"PCHG2":41.83676,"CHG":2.48154,"PCHG":31.57051,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"2","BTOXGR":"-1","ADTM":"2020-12-26 00:04:12","ADY":221,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-215","SUBJID":"id-215","SITEID":"NGA-4","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":10.49773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-15","TRTSDTM":"2020-05-19 00:04:12","TRTEDTM":"2022-02-18 10:40:54","TRT01SDTM":"2020-05-19 00:04:12","TRT01EDTM":"2021-02-18 04:40:54","TRT02SDTM":"2021-02-18 04:40:54","TRT02EDTM":"2022-02-18 10:40:54","AP01SDTM":"2020-05-19 00:04:12","AP01EDTM":"2021-02-18 04:40:54","AP02SDTM":"2021-02-18 04:40:54","AP02EDTM":"2022-02-18 10:40:54","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":641,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":647,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4453,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.46611,"AVALU":"mg/L","BASE2":7.29138,"BASE":7.86032,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.17473,"PCHG2":16.1112,"CHG":0.60579,"PCHG":7.70699,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-01-28 00:04:12","ADY":619,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-215","SUBJID":"id-215","SITEID":"NGA-4","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":10.49773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-15","TRTSDTM":"2020-05-19 00:04:12","TRTEDTM":"2022-02-18 10:40:54","TRT01SDTM":"2020-05-19 00:04:12","TRT01EDTM":"2021-02-18 04:40:54","TRT02SDTM":"2021-02-18 04:40:54","TRT02EDTM":"2022-02-18 10:40:54","AP01SDTM":"2020-05-19 00:04:12","AP01EDTM":"2021-02-18 04:40:54","AP02SDTM":"2021-02-18 04:40:54","AP02EDTM":"2022-02-18 10:40:54","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":641,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":647,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2677,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99529,"AVALU":"g/L","BASE2":2.99529,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-31 00:04:12","ADY":12,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-215","SUBJID":"id-215","SITEID":"NGA-4","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":10.49773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-15","TRTSDTM":"2020-05-19 00:04:12","TRTEDTM":"2022-02-18 10:40:54","TRT01SDTM":"2020-05-19 00:04:12","TRT01EDTM":"2021-02-18 04:40:54","TRT02SDTM":"2021-02-18 04:40:54","TRT02EDTM":"2022-02-18 10:40:54","AP01SDTM":"2020-05-19 00:04:12","AP01EDTM":"2021-02-18 04:40:54","AP02SDTM":"2021-02-18 04:40:54","AP02EDTM":"2022-02-18 10:40:54","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":641,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":647,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8044,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89,"AVALU":"g/L","BASE2":2.99529,"BASE":2.89,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.10529,"PCHG2":-3.51529,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-21 00:04:12","ADY":63,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-215","SUBJID":"id-215","SITEID":"NGA-4","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":10.49773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-15","TRTSDTM":"2020-05-19 00:04:12","TRTEDTM":"2022-02-18 10:40:54","TRT01SDTM":"2020-05-19 00:04:12","TRT01EDTM":"2021-02-18 04:40:54","TRT02SDTM":"2021-02-18 04:40:54","TRT02EDTM":"2022-02-18 10:40:54","AP01SDTM":"2020-05-19 00:04:12","AP01EDTM":"2021-02-18 04:40:54","AP02SDTM":"2021-02-18 04:40:54","AP02EDTM":"2022-02-18 10:40:54","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":641,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":647,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1767,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9385,"AVALU":"g/L","BASE2":2.99529,"BASE":2.89,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05679,"PCHG2":-1.89591,"CHG":0.04851,"PCHG":1.67838,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-14 00:04:12","ADY":118,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-215","SUBJID":"id-215","SITEID":"NGA-4","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":10.49773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-15","TRTSDTM":"2020-05-19 00:04:12","TRTEDTM":"2022-02-18 10:40:54","TRT01SDTM":"2020-05-19 00:04:12","TRT01EDTM":"2021-02-18 04:40:54","TRT02SDTM":"2021-02-18 04:40:54","TRT02EDTM":"2022-02-18 10:40:54","AP01SDTM":"2020-05-19 00:04:12","AP01EDTM":"2021-02-18 04:40:54","AP02SDTM":"2021-02-18 04:40:54","AP02EDTM":"2022-02-18 10:40:54","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":641,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":647,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2357,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78352,"AVALU":"g/L","BASE2":2.99529,"BASE":2.89,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21177,"PCHG2":-7.07017,"CHG":-0.10648,"PCHG":-3.6844,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-04 00:04:12","ADY":138,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-215","SUBJID":"id-215","SITEID":"NGA-4","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":10.49773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-15","TRTSDTM":"2020-05-19 00:04:12","TRTEDTM":"2022-02-18 10:40:54","TRT01SDTM":"2020-05-19 00:04:12","TRT01EDTM":"2021-02-18 04:40:54","TRT02SDTM":"2021-02-18 04:40:54","TRT02EDTM":"2022-02-18 10:40:54","AP01SDTM":"2020-05-19 00:04:12","AP01EDTM":"2021-02-18 04:40:54","AP02SDTM":"2021-02-18 04:40:54","AP02EDTM":"2022-02-18 10:40:54","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":641,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":647,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":83,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91084,"AVALU":"g/L","BASE2":2.99529,"BASE":2.89,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08445,"PCHG2":-2.81953,"CHG":0.02084,"PCHG":0.72111,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-31 00:04:12","ADY":165,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-215","SUBJID":"id-215","SITEID":"NGA-4","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":10.49773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-15","TRTSDTM":"2020-05-19 00:04:12","TRTEDTM":"2022-02-18 10:40:54","TRT01SDTM":"2020-05-19 00:04:12","TRT01EDTM":"2021-02-18 04:40:54","TRT02SDTM":"2021-02-18 04:40:54","TRT02EDTM":"2022-02-18 10:40:54","AP01SDTM":"2020-05-19 00:04:12","AP01EDTM":"2021-02-18 04:40:54","AP02SDTM":"2021-02-18 04:40:54","AP02EDTM":"2022-02-18 10:40:54","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":641,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":647,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6772,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91879,"AVALU":"g/L","BASE2":2.99529,"BASE":2.89,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07651,"PCHG2":-2.55425,"CHG":0.02879,"PCHG":0.99606,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-26 00:04:12","ADY":221,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-215","SUBJID":"id-215","SITEID":"NGA-4","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"Y","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S1","BMRKR1":10.49773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-05-15","TRTSDTM":"2020-05-19 00:04:12","TRTEDTM":"2022-02-18 10:40:54","TRT01SDTM":"2020-05-19 00:04:12","TRT01EDTM":"2021-02-18 04:40:54","TRT02SDTM":"2021-02-18 04:40:54","TRT02EDTM":"2022-02-18 10:40:54","AP01SDTM":"2020-05-19 00:04:12","AP01EDTM":"2021-02-18 04:40:54","AP02SDTM":"2021-02-18 04:40:54","AP02EDTM":"2022-02-18 10:40:54","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":641,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":8,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":647,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8008,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88752,"AVALU":"g/L","BASE2":2.99529,"BASE":2.89,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10778,"PCHG2":-3.59817,"CHG":-0.00248,"PCHG":-0.0859,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-28 00:04:12","ADY":619,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-37","SUBJID":"id-37","SITEID":"NGA-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57225,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 20:10:19","TRTEDTM":"2023-08-18 14:10:19","TRT01SDTM":"2020-08-17 20:10:19","TRT01EDTM":"2022-08-18 08:10:19","TRT02SDTM":"2022-08-18 08:10:19","TRT02EDTM":"2023-08-18 14:10:19","AP01SDTM":"2020-08-17 20:10:19","AP01EDTM":"2022-08-18 08:10:19","AP02SDTM":"2022-08-18 08:10:19","AP02EDTM":"2023-08-18 14:10:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-03","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2277,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.94185,"AVALU":"U/L","BASE2":14.94185,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-02 20:10:19","ADY":319,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-37","SUBJID":"id-37","SITEID":"NGA-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57225,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 20:10:19","TRTEDTM":"2023-08-18 14:10:19","TRT01SDTM":"2020-08-17 20:10:19","TRT01EDTM":"2022-08-18 08:10:19","TRT02SDTM":"2022-08-18 08:10:19","TRT02EDTM":"2023-08-18 14:10:19","AP01SDTM":"2020-08-17 20:10:19","AP01EDTM":"2022-08-18 08:10:19","AP02SDTM":"2022-08-18 08:10:19","AP02EDTM":"2023-08-18 14:10:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-03","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3798,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.88074,"AVALU":"U/L","BASE2":14.94185,"BASE":8.88074,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-6.0611,"PCHG2":-40.56463,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-01 20:10:19","ADY":441,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-37","SUBJID":"id-37","SITEID":"NGA-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57225,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 20:10:19","TRTEDTM":"2023-08-18 14:10:19","TRT01SDTM":"2020-08-17 20:10:19","TRT01EDTM":"2022-08-18 08:10:19","TRT02SDTM":"2022-08-18 08:10:19","TRT02EDTM":"2023-08-18 14:10:19","AP01SDTM":"2020-08-17 20:10:19","AP01EDTM":"2022-08-18 08:10:19","AP02SDTM":"2022-08-18 08:10:19","AP02EDTM":"2023-08-18 14:10:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-03","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3367,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.91226,"AVALU":"U/L","BASE2":14.94185,"BASE":8.88074,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.02959,"PCHG2":-73.81677,"CHG":-4.96848,"PCHG":-55.94672,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-11-15 20:10:19","ADY":455,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-37","SUBJID":"id-37","SITEID":"NGA-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57225,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 20:10:19","TRTEDTM":"2023-08-18 14:10:19","TRT01SDTM":"2020-08-17 20:10:19","TRT01EDTM":"2022-08-18 08:10:19","TRT02SDTM":"2022-08-18 08:10:19","TRT02EDTM":"2023-08-18 14:10:19","AP01SDTM":"2020-08-17 20:10:19","AP01EDTM":"2022-08-18 08:10:19","AP02SDTM":"2022-08-18 08:10:19","AP02EDTM":"2023-08-18 14:10:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-03","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5073,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.57689,"AVALU":"U/L","BASE2":14.94185,"BASE":8.88074,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.63504,"PCHG2":91.25408,"CHG":19.69615,"PCHG":221.78495,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-12 20:10:19","ADY":544,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-37","SUBJID":"id-37","SITEID":"NGA-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57225,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 20:10:19","TRTEDTM":"2023-08-18 14:10:19","TRT01SDTM":"2020-08-17 20:10:19","TRT01EDTM":"2022-08-18 08:10:19","TRT02SDTM":"2022-08-18 08:10:19","TRT02EDTM":"2023-08-18 14:10:19","AP01SDTM":"2020-08-17 20:10:19","AP01EDTM":"2022-08-18 08:10:19","AP02SDTM":"2022-08-18 08:10:19","AP02EDTM":"2023-08-18 14:10:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-03","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7917,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.50998,"AVALU":"U/L","BASE2":14.94185,"BASE":8.88074,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.56813,"PCHG2":124.26935,"CHG":24.62924,"PCHG":277.33315,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-09 20:10:19","ADY":753,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-37","SUBJID":"id-37","SITEID":"NGA-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57225,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 20:10:19","TRTEDTM":"2023-08-18 14:10:19","TRT01SDTM":"2020-08-17 20:10:19","TRT01EDTM":"2022-08-18 08:10:19","TRT02SDTM":"2022-08-18 08:10:19","TRT02EDTM":"2023-08-18 14:10:19","AP01SDTM":"2020-08-17 20:10:19","AP01EDTM":"2022-08-18 08:10:19","AP02SDTM":"2022-08-18 08:10:19","AP02EDTM":"2023-08-18 14:10:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-03","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5293,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.56121,"AVALU":"U/L","BASE2":14.94185,"BASE":8.88074,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.61937,"PCHG2":57.6861,"CHG":14.68047,"PCHG":165.30683,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-10 20:10:19","ADY":935,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-37","SUBJID":"id-37","SITEID":"NGA-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57225,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 20:10:19","TRTEDTM":"2023-08-18 14:10:19","TRT01SDTM":"2020-08-17 20:10:19","TRT01EDTM":"2022-08-18 08:10:19","TRT02SDTM":"2022-08-18 08:10:19","TRT02EDTM":"2023-08-18 14:10:19","AP01SDTM":"2020-08-17 20:10:19","AP01EDTM":"2022-08-18 08:10:19","AP02SDTM":"2022-08-18 08:10:19","AP02EDTM":"2023-08-18 14:10:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-03","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1902,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.82788,"AVALU":"U/L","BASE2":14.94185,"BASE":8.88074,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.88604,"PCHG2":92.93388,"CHG":19.94714,"PCHG":224.61123,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-04 20:10:19","ADY":1021,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-37","SUBJID":"id-37","SITEID":"NGA-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57225,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 20:10:19","TRTEDTM":"2023-08-18 14:10:19","TRT01SDTM":"2020-08-17 20:10:19","TRT01EDTM":"2022-08-18 08:10:19","TRT02SDTM":"2022-08-18 08:10:19","TRT02EDTM":"2023-08-18 14:10:19","AP01SDTM":"2020-08-17 20:10:19","AP01EDTM":"2022-08-18 08:10:19","AP02SDTM":"2022-08-18 08:10:19","AP02EDTM":"2023-08-18 14:10:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-03","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1878,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.21039,"AVALU":"mg/L","BASE2":9.21039,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-02 20:10:19","ADY":319,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-37","SUBJID":"id-37","SITEID":"NGA-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57225,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 20:10:19","TRTEDTM":"2023-08-18 14:10:19","TRT01SDTM":"2020-08-17 20:10:19","TRT01EDTM":"2022-08-18 08:10:19","TRT02SDTM":"2022-08-18 08:10:19","TRT02EDTM":"2023-08-18 14:10:19","AP01SDTM":"2020-08-17 20:10:19","AP01EDTM":"2022-08-18 08:10:19","AP02SDTM":"2022-08-18 08:10:19","AP02EDTM":"2023-08-18 14:10:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-03","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3607,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.83374,"AVALU":"mg/L","BASE2":9.21039,"BASE":9.83374,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.62336,"PCHG2":6.76796,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-01 20:10:19","ADY":441,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-37","SUBJID":"id-37","SITEID":"NGA-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57225,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 20:10:19","TRTEDTM":"2023-08-18 14:10:19","TRT01SDTM":"2020-08-17 20:10:19","TRT01EDTM":"2022-08-18 08:10:19","TRT02SDTM":"2022-08-18 08:10:19","TRT02EDTM":"2023-08-18 14:10:19","AP01SDTM":"2020-08-17 20:10:19","AP01EDTM":"2022-08-18 08:10:19","AP02SDTM":"2022-08-18 08:10:19","AP02EDTM":"2023-08-18 14:10:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-03","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1777,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.70237,"AVALU":"mg/L","BASE2":9.21039,"BASE":9.83374,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.49198,"PCHG2":5.34162,"CHG":-0.13137,"PCHG":-1.33592,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-15 20:10:19","ADY":455,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-37","SUBJID":"id-37","SITEID":"NGA-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57225,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 20:10:19","TRTEDTM":"2023-08-18 14:10:19","TRT01SDTM":"2020-08-17 20:10:19","TRT01EDTM":"2022-08-18 08:10:19","TRT02SDTM":"2022-08-18 08:10:19","TRT02EDTM":"2023-08-18 14:10:19","AP01SDTM":"2020-08-17 20:10:19","AP01EDTM":"2022-08-18 08:10:19","AP02SDTM":"2022-08-18 08:10:19","AP02EDTM":"2023-08-18 14:10:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-03","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7985,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.88984,"AVALU":"mg/L","BASE2":9.21039,"BASE":9.83374,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.32055,"PCHG2":-14.33756,"CHG":-1.9439,"PCHG":-19.76765,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2022-02-12 20:10:19","ADY":544,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-37","SUBJID":"id-37","SITEID":"NGA-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57225,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 20:10:19","TRTEDTM":"2023-08-18 14:10:19","TRT01SDTM":"2020-08-17 20:10:19","TRT01EDTM":"2022-08-18 08:10:19","TRT02SDTM":"2022-08-18 08:10:19","TRT02EDTM":"2023-08-18 14:10:19","AP01SDTM":"2020-08-17 20:10:19","AP01EDTM":"2022-08-18 08:10:19","AP02SDTM":"2022-08-18 08:10:19","AP02EDTM":"2023-08-18 14:10:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-03","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2308,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.03886,"AVALU":"mg/L","BASE2":9.21039,"BASE":9.83374,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.17153,"PCHG2":-12.71962,"CHG":-1.79488,"PCHG":-18.25227,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-09 20:10:19","ADY":753,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-37","SUBJID":"id-37","SITEID":"NGA-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57225,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 20:10:19","TRTEDTM":"2023-08-18 14:10:19","TRT01SDTM":"2020-08-17 20:10:19","TRT01EDTM":"2022-08-18 08:10:19","TRT02SDTM":"2022-08-18 08:10:19","TRT02EDTM":"2023-08-18 14:10:19","AP01SDTM":"2020-08-17 20:10:19","AP01EDTM":"2022-08-18 08:10:19","AP02SDTM":"2022-08-18 08:10:19","AP02EDTM":"2023-08-18 14:10:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-03","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6778,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.43942,"AVALU":"mg/L","BASE2":9.21039,"BASE":9.83374,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.77097,"PCHG2":-19.228,"CHG":-2.39433,"PCHG":-24.34809,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2023-03-10 20:10:19","ADY":935,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-37","SUBJID":"id-37","SITEID":"NGA-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57225,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 20:10:19","TRTEDTM":"2023-08-18 14:10:19","TRT01SDTM":"2020-08-17 20:10:19","TRT01EDTM":"2022-08-18 08:10:19","TRT02SDTM":"2022-08-18 08:10:19","TRT02EDTM":"2023-08-18 14:10:19","AP01SDTM":"2020-08-17 20:10:19","AP01EDTM":"2022-08-18 08:10:19","AP02SDTM":"2022-08-18 08:10:19","AP02EDTM":"2023-08-18 14:10:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-03","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6506,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.38329,"AVALU":"mg/L","BASE2":9.21039,"BASE":9.83374,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.8271,"PCHG2":-8.98004,"CHG":-1.45045,"PCHG":-14.74974,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-04 20:10:19","ADY":1021,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-37","SUBJID":"id-37","SITEID":"NGA-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57225,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 20:10:19","TRTEDTM":"2023-08-18 14:10:19","TRT01SDTM":"2020-08-17 20:10:19","TRT01EDTM":"2022-08-18 08:10:19","TRT02SDTM":"2022-08-18 08:10:19","TRT02EDTM":"2023-08-18 14:10:19","AP01SDTM":"2020-08-17 20:10:19","AP01EDTM":"2022-08-18 08:10:19","AP02SDTM":"2022-08-18 08:10:19","AP02EDTM":"2023-08-18 14:10:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-03","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4671,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80105,"AVALU":"g/L","BASE2":2.80105,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-02 20:10:19","ADY":319,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-37","SUBJID":"id-37","SITEID":"NGA-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57225,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 20:10:19","TRTEDTM":"2023-08-18 14:10:19","TRT01SDTM":"2020-08-17 20:10:19","TRT01EDTM":"2022-08-18 08:10:19","TRT02SDTM":"2022-08-18 08:10:19","TRT02EDTM":"2023-08-18 14:10:19","AP01SDTM":"2020-08-17 20:10:19","AP01EDTM":"2022-08-18 08:10:19","AP02SDTM":"2022-08-18 08:10:19","AP02EDTM":"2023-08-18 14:10:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-03","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2340,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88099,"AVALU":"g/L","BASE2":2.80105,"BASE":2.88099,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.07993,"PCHG2":2.85372,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-01 20:10:19","ADY":441,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-37","SUBJID":"id-37","SITEID":"NGA-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57225,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 20:10:19","TRTEDTM":"2023-08-18 14:10:19","TRT01SDTM":"2020-08-17 20:10:19","TRT01EDTM":"2022-08-18 08:10:19","TRT02SDTM":"2022-08-18 08:10:19","TRT02EDTM":"2023-08-18 14:10:19","AP01SDTM":"2020-08-17 20:10:19","AP01EDTM":"2022-08-18 08:10:19","AP02SDTM":"2022-08-18 08:10:19","AP02EDTM":"2023-08-18 14:10:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-03","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6339,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79351,"AVALU":"g/L","BASE2":2.80105,"BASE":2.88099,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00755,"PCHG2":-0.26944,"CHG":-0.08748,"PCHG":-3.03651,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-15 20:10:19","ADY":455,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-37","SUBJID":"id-37","SITEID":"NGA-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57225,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 20:10:19","TRTEDTM":"2023-08-18 14:10:19","TRT01SDTM":"2020-08-17 20:10:19","TRT01EDTM":"2022-08-18 08:10:19","TRT02SDTM":"2022-08-18 08:10:19","TRT02EDTM":"2023-08-18 14:10:19","AP01SDTM":"2020-08-17 20:10:19","AP01EDTM":"2022-08-18 08:10:19","AP02SDTM":"2022-08-18 08:10:19","AP02EDTM":"2023-08-18 14:10:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-03","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6542,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78908,"AVALU":"g/L","BASE2":2.80105,"BASE":2.88099,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01197,"PCHG2":-0.42746,"CHG":-0.09191,"PCHG":-3.19014,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-12 20:10:19","ADY":544,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-37","SUBJID":"id-37","SITEID":"NGA-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57225,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 20:10:19","TRTEDTM":"2023-08-18 14:10:19","TRT01SDTM":"2020-08-17 20:10:19","TRT01EDTM":"2022-08-18 08:10:19","TRT02SDTM":"2022-08-18 08:10:19","TRT02EDTM":"2023-08-18 14:10:19","AP01SDTM":"2020-08-17 20:10:19","AP01EDTM":"2022-08-18 08:10:19","AP02SDTM":"2022-08-18 08:10:19","AP02EDTM":"2023-08-18 14:10:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-03","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1550,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87933,"AVALU":"g/L","BASE2":2.80105,"BASE":2.88099,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07828,"PCHG2":2.79453,"CHG":-0.00166,"PCHG":-0.05755,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-09 20:10:19","ADY":753,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-37","SUBJID":"id-37","SITEID":"NGA-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57225,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 20:10:19","TRTEDTM":"2023-08-18 14:10:19","TRT01SDTM":"2020-08-17 20:10:19","TRT01EDTM":"2022-08-18 08:10:19","TRT02SDTM":"2022-08-18 08:10:19","TRT02EDTM":"2023-08-18 14:10:19","AP01SDTM":"2020-08-17 20:10:19","AP01EDTM":"2022-08-18 08:10:19","AP02SDTM":"2022-08-18 08:10:19","AP02EDTM":"2023-08-18 14:10:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-03","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4142,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94561,"AVALU":"g/L","BASE2":2.80105,"BASE":2.88099,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14455,"PCHG2":5.16062,"CHG":0.06462,"PCHG":2.24289,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-03-10 20:10:19","ADY":935,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-4-id-37","SUBJID":"id-37","SITEID":"NGA-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-4","INVNAM":"Dr. NGA-4 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"C","STRATA2":"S1","BMRKR1":4.57225,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 20:10:19","TRTEDTM":"2023-08-18 14:10:19","TRT01SDTM":"2020-08-17 20:10:19","TRT01EDTM":"2022-08-18 08:10:19","TRT02SDTM":"2022-08-18 08:10:19","TRT02EDTM":"2023-08-18 14:10:19","AP01SDTM":"2020-08-17 20:10:19","AP01EDTM":"2022-08-18 08:10:19","AP02SDTM":"2022-08-18 08:10:19","AP02EDTM":"2023-08-18 14:10:19","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-03","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5619,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0081,"AVALU":"g/L","BASE2":2.80105,"BASE":2.88099,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.20704,"PCHG2":7.39159,"CHG":0.12711,"PCHG":4.41196,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2023-06-04 20:10:19","ADY":1021,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-5-id-99","SUBJID":"id-99","SITEID":"NGA-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-5","INVNAM":"Dr. NGA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":5.48616,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-30","TRTSDTM":"2020-12-04 03:19:40","TRTEDTM":"2023-12-04 21:19:40","TRT01SDTM":"2020-12-04 03:19:40","TRT01EDTM":"2022-12-04 15:19:40","TRT02SDTM":"2022-12-04 15:19:40","TRT02EDTM":"2023-12-04 21:19:40","AP01SDTM":"2020-12-04 03:19:40","AP01EDTM":"2022-12-04 15:19:40","AP02SDTM":"2022-12-04 15:19:40","AP02EDTM":"2023-12-04 21:19:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-04","EOSDY":1096,"LSTALVDT":"2024-01-02","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2294,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.14002,"AVALU":"U/L","BASE2":31.14002,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-25 03:19:40","ADY":83,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-5-id-99","SUBJID":"id-99","SITEID":"NGA-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-5","INVNAM":"Dr. NGA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":5.48616,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-30","TRTSDTM":"2020-12-04 03:19:40","TRTEDTM":"2023-12-04 21:19:40","TRT01SDTM":"2020-12-04 03:19:40","TRT01EDTM":"2022-12-04 15:19:40","TRT02SDTM":"2022-12-04 15:19:40","TRT02EDTM":"2023-12-04 21:19:40","AP01SDTM":"2020-12-04 03:19:40","AP01EDTM":"2022-12-04 15:19:40","AP02SDTM":"2022-12-04 15:19:40","AP02EDTM":"2023-12-04 21:19:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-04","EOSDY":1096,"LSTALVDT":"2024-01-02","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":468,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.30603,"AVALU":"U/L","BASE2":31.14002,"BASE":15.30603,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-15.83399,"PCHG2":-50.84773,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-10 03:19:40","ADY":492,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-5-id-99","SUBJID":"id-99","SITEID":"NGA-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-5","INVNAM":"Dr. NGA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":5.48616,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-30","TRTSDTM":"2020-12-04 03:19:40","TRTEDTM":"2023-12-04 21:19:40","TRT01SDTM":"2020-12-04 03:19:40","TRT01EDTM":"2022-12-04 15:19:40","TRT02SDTM":"2022-12-04 15:19:40","TRT02EDTM":"2023-12-04 21:19:40","AP01SDTM":"2020-12-04 03:19:40","AP01EDTM":"2022-12-04 15:19:40","AP02SDTM":"2022-12-04 15:19:40","AP02EDTM":"2023-12-04 21:19:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-04","EOSDY":1096,"LSTALVDT":"2024-01-02","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":235,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.04406,"AVALU":"U/L","BASE2":31.14002,"BASE":15.30603,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.09596,"PCHG2":-45.26638,"CHG":1.73803,"PCHG":11.35523,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-26 03:19:40","ADY":964,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-5-id-99","SUBJID":"id-99","SITEID":"NGA-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-5","INVNAM":"Dr. NGA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":5.48616,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-30","TRTSDTM":"2020-12-04 03:19:40","TRTEDTM":"2023-12-04 21:19:40","TRT01SDTM":"2020-12-04 03:19:40","TRT01EDTM":"2022-12-04 15:19:40","TRT02SDTM":"2022-12-04 15:19:40","TRT02EDTM":"2023-12-04 21:19:40","AP01SDTM":"2020-12-04 03:19:40","AP01EDTM":"2022-12-04 15:19:40","AP02SDTM":"2022-12-04 15:19:40","AP02EDTM":"2023-12-04 21:19:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-04","EOSDY":1096,"LSTALVDT":"2024-01-02","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3257,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.38409,"AVALU":"U/L","BASE2":31.14002,"BASE":15.30603,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.75593,"PCHG2":-44.17445,"CHG":2.07806,"PCHG":13.57676,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-04 03:19:40","ADY":1004,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-5-id-99","SUBJID":"id-99","SITEID":"NGA-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-5","INVNAM":"Dr. NGA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":5.48616,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-30","TRTSDTM":"2020-12-04 03:19:40","TRTEDTM":"2023-12-04 21:19:40","TRT01SDTM":"2020-12-04 03:19:40","TRT01EDTM":"2022-12-04 15:19:40","TRT02SDTM":"2022-12-04 15:19:40","TRT02EDTM":"2023-12-04 21:19:40","AP01SDTM":"2020-12-04 03:19:40","AP01EDTM":"2022-12-04 15:19:40","AP02SDTM":"2022-12-04 15:19:40","AP02EDTM":"2023-12-04 21:19:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-04","EOSDY":1096,"LSTALVDT":"2024-01-02","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1325,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.08477,"AVALU":"U/L","BASE2":31.14002,"BASE":15.30603,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-22.05525,"PCHG2":-70.82607,"CHG":-6.22126,"PCHG":-40.64581,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-10-14 03:19:40","ADY":1044,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-5-id-99","SUBJID":"id-99","SITEID":"NGA-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-5","INVNAM":"Dr. NGA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":5.48616,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-30","TRTSDTM":"2020-12-04 03:19:40","TRTEDTM":"2023-12-04 21:19:40","TRT01SDTM":"2020-12-04 03:19:40","TRT01EDTM":"2022-12-04 15:19:40","TRT02SDTM":"2022-12-04 15:19:40","TRT02EDTM":"2023-12-04 21:19:40","AP01SDTM":"2020-12-04 03:19:40","AP01EDTM":"2022-12-04 15:19:40","AP02SDTM":"2022-12-04 15:19:40","AP02EDTM":"2023-12-04 21:19:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-04","EOSDY":1096,"LSTALVDT":"2024-01-02","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3030,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.8524,"AVALU":"U/L","BASE2":31.14002,"BASE":15.30603,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-21.28762,"PCHG2":-68.36097,"CHG":-5.45363,"PCHG":-35.63058,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-11-23 03:19:40","ADY":1084,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-5-id-99","SUBJID":"id-99","SITEID":"NGA-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-5","INVNAM":"Dr. NGA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":5.48616,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-30","TRTSDTM":"2020-12-04 03:19:40","TRTEDTM":"2023-12-04 21:19:40","TRT01SDTM":"2020-12-04 03:19:40","TRT01EDTM":"2022-12-04 15:19:40","TRT02SDTM":"2022-12-04 15:19:40","TRT02EDTM":"2023-12-04 21:19:40","AP01SDTM":"2020-12-04 03:19:40","AP01EDTM":"2022-12-04 15:19:40","AP02SDTM":"2022-12-04 15:19:40","AP02EDTM":"2023-12-04 21:19:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-04","EOSDY":1096,"LSTALVDT":"2024-01-02","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6663,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.95054,"AVALU":"U/L","BASE2":31.14002,"BASE":15.30603,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.18948,"PCHG2":-7.03108,"CHG":13.64452,"PCHG":89.14472,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-11-24 03:19:40","ADY":1085,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-5-id-99","SUBJID":"id-99","SITEID":"NGA-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-5","INVNAM":"Dr. NGA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":5.48616,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-30","TRTSDTM":"2020-12-04 03:19:40","TRTEDTM":"2023-12-04 21:19:40","TRT01SDTM":"2020-12-04 03:19:40","TRT01EDTM":"2022-12-04 15:19:40","TRT02SDTM":"2022-12-04 15:19:40","TRT02EDTM":"2023-12-04 21:19:40","AP01SDTM":"2020-12-04 03:19:40","AP01EDTM":"2022-12-04 15:19:40","AP02SDTM":"2022-12-04 15:19:40","AP02EDTM":"2023-12-04 21:19:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-04","EOSDY":1096,"LSTALVDT":"2024-01-02","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2929,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.52884,"AVALU":"mg/L","BASE2":8.52884,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-25 03:19:40","ADY":83,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-5-id-99","SUBJID":"id-99","SITEID":"NGA-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-5","INVNAM":"Dr. NGA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":5.48616,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-30","TRTSDTM":"2020-12-04 03:19:40","TRTEDTM":"2023-12-04 21:19:40","TRT01SDTM":"2020-12-04 03:19:40","TRT01EDTM":"2022-12-04 15:19:40","TRT02SDTM":"2022-12-04 15:19:40","TRT02EDTM":"2023-12-04 21:19:40","AP01SDTM":"2020-12-04 03:19:40","AP01EDTM":"2022-12-04 15:19:40","AP02SDTM":"2022-12-04 15:19:40","AP02EDTM":"2023-12-04 21:19:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-04","EOSDY":1096,"LSTALVDT":"2024-01-02","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4963,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.97132,"AVALU":"mg/L","BASE2":8.52884,"BASE":9.97132,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.44248,"PCHG2":16.91303,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-10 03:19:40","ADY":492,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-5-id-99","SUBJID":"id-99","SITEID":"NGA-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-5","INVNAM":"Dr. NGA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":5.48616,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-30","TRTSDTM":"2020-12-04 03:19:40","TRTEDTM":"2023-12-04 21:19:40","TRT01SDTM":"2020-12-04 03:19:40","TRT01EDTM":"2022-12-04 15:19:40","TRT02SDTM":"2022-12-04 15:19:40","TRT02EDTM":"2023-12-04 21:19:40","AP01SDTM":"2020-12-04 03:19:40","AP01EDTM":"2022-12-04 15:19:40","AP02SDTM":"2022-12-04 15:19:40","AP02EDTM":"2023-12-04 21:19:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-04","EOSDY":1096,"LSTALVDT":"2024-01-02","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6372,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.96432,"AVALU":"mg/L","BASE2":8.52884,"BASE":9.97132,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.43549,"PCHG2":5.10604,"CHG":-1.007,"PCHG":-10.09895,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-26 03:19:40","ADY":964,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-5-id-99","SUBJID":"id-99","SITEID":"NGA-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-5","INVNAM":"Dr. NGA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":5.48616,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-30","TRTSDTM":"2020-12-04 03:19:40","TRTEDTM":"2023-12-04 21:19:40","TRT01SDTM":"2020-12-04 03:19:40","TRT01EDTM":"2022-12-04 15:19:40","TRT02SDTM":"2022-12-04 15:19:40","TRT02EDTM":"2023-12-04 21:19:40","AP01SDTM":"2020-12-04 03:19:40","AP01EDTM":"2022-12-04 15:19:40","AP02SDTM":"2022-12-04 15:19:40","AP02EDTM":"2023-12-04 21:19:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-04","EOSDY":1096,"LSTALVDT":"2024-01-02","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2075,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.16238,"AVALU":"mg/L","BASE2":8.52884,"BASE":9.97132,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.63354,"PCHG2":19.15317,"CHG":0.19106,"PCHG":1.91607,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2023-09-04 03:19:40","ADY":1004,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-5-id-99","SUBJID":"id-99","SITEID":"NGA-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-5","INVNAM":"Dr. NGA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":5.48616,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-30","TRTSDTM":"2020-12-04 03:19:40","TRTEDTM":"2023-12-04 21:19:40","TRT01SDTM":"2020-12-04 03:19:40","TRT01EDTM":"2022-12-04 15:19:40","TRT02SDTM":"2022-12-04 15:19:40","TRT02EDTM":"2023-12-04 21:19:40","AP01SDTM":"2020-12-04 03:19:40","AP01EDTM":"2022-12-04 15:19:40","AP02SDTM":"2022-12-04 15:19:40","AP02EDTM":"2023-12-04 21:19:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-04","EOSDY":1096,"LSTALVDT":"2024-01-02","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1349,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.41192,"AVALU":"mg/L","BASE2":8.52884,"BASE":9.97132,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.88308,"PCHG2":10.35405,"CHG":-0.5594,"PCHG":-5.61013,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-10-14 03:19:40","ADY":1044,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-5-id-99","SUBJID":"id-99","SITEID":"NGA-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-5","INVNAM":"Dr. NGA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":5.48616,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-30","TRTSDTM":"2020-12-04 03:19:40","TRTEDTM":"2023-12-04 21:19:40","TRT01SDTM":"2020-12-04 03:19:40","TRT01EDTM":"2022-12-04 15:19:40","TRT02SDTM":"2022-12-04 15:19:40","TRT02EDTM":"2023-12-04 21:19:40","AP01SDTM":"2020-12-04 03:19:40","AP01EDTM":"2022-12-04 15:19:40","AP02SDTM":"2022-12-04 15:19:40","AP02EDTM":"2023-12-04 21:19:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-04","EOSDY":1096,"LSTALVDT":"2024-01-02","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6634,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.98679,"AVALU":"mg/L","BASE2":8.52884,"BASE":9.97132,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.45796,"PCHG2":28.81936,"CHG":1.01547,"PCHG":10.18393,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2023-11-23 03:19:40","ADY":1084,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-5-id-99","SUBJID":"id-99","SITEID":"NGA-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-5","INVNAM":"Dr. NGA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":5.48616,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-30","TRTSDTM":"2020-12-04 03:19:40","TRTEDTM":"2023-12-04 21:19:40","TRT01SDTM":"2020-12-04 03:19:40","TRT01EDTM":"2022-12-04 15:19:40","TRT02SDTM":"2022-12-04 15:19:40","TRT02EDTM":"2023-12-04 21:19:40","AP01SDTM":"2020-12-04 03:19:40","AP01EDTM":"2022-12-04 15:19:40","AP02SDTM":"2022-12-04 15:19:40","AP02EDTM":"2023-12-04 21:19:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-04","EOSDY":1096,"LSTALVDT":"2024-01-02","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4644,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.80509,"AVALU":"mg/L","BASE2":8.52884,"BASE":9.97132,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.72375,"PCHG2":-8.48586,"CHG":-2.16623,"PCHG":-21.7246,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2023-11-24 03:19:40","ADY":1085,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-5-id-99","SUBJID":"id-99","SITEID":"NGA-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-5","INVNAM":"Dr. NGA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":5.48616,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-30","TRTSDTM":"2020-12-04 03:19:40","TRTEDTM":"2023-12-04 21:19:40","TRT01SDTM":"2020-12-04 03:19:40","TRT01EDTM":"2022-12-04 15:19:40","TRT02SDTM":"2022-12-04 15:19:40","TRT02EDTM":"2023-12-04 21:19:40","AP01SDTM":"2020-12-04 03:19:40","AP01EDTM":"2022-12-04 15:19:40","AP02SDTM":"2022-12-04 15:19:40","AP02EDTM":"2023-12-04 21:19:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-04","EOSDY":1096,"LSTALVDT":"2024-01-02","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7806,"AVALU":"g/L","BASE2":2.7806,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-25 03:19:40","ADY":83,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-5-id-99","SUBJID":"id-99","SITEID":"NGA-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-5","INVNAM":"Dr. NGA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":5.48616,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-30","TRTSDTM":"2020-12-04 03:19:40","TRTEDTM":"2023-12-04 21:19:40","TRT01SDTM":"2020-12-04 03:19:40","TRT01EDTM":"2022-12-04 15:19:40","TRT02SDTM":"2022-12-04 15:19:40","TRT02EDTM":"2023-12-04 21:19:40","AP01SDTM":"2020-12-04 03:19:40","AP01EDTM":"2022-12-04 15:19:40","AP02SDTM":"2022-12-04 15:19:40","AP02EDTM":"2023-12-04 21:19:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-04","EOSDY":1096,"LSTALVDT":"2024-01-02","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":766,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96904,"AVALU":"g/L","BASE2":2.7806,"BASE":2.96904,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.18844,"PCHG2":6.77694,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-10 03:19:40","ADY":492,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-5-id-99","SUBJID":"id-99","SITEID":"NGA-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-5","INVNAM":"Dr. NGA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":5.48616,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-30","TRTSDTM":"2020-12-04 03:19:40","TRTEDTM":"2023-12-04 21:19:40","TRT01SDTM":"2020-12-04 03:19:40","TRT01EDTM":"2022-12-04 15:19:40","TRT02SDTM":"2022-12-04 15:19:40","TRT02EDTM":"2023-12-04 21:19:40","AP01SDTM":"2020-12-04 03:19:40","AP01EDTM":"2022-12-04 15:19:40","AP02SDTM":"2022-12-04 15:19:40","AP02EDTM":"2023-12-04 21:19:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-04","EOSDY":1096,"LSTALVDT":"2024-01-02","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3364,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84699,"AVALU":"g/L","BASE2":2.7806,"BASE":2.96904,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0664,"PCHG2":2.38789,"CHG":-0.12204,"PCHG":-4.11049,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-26 03:19:40","ADY":964,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-5-id-99","SUBJID":"id-99","SITEID":"NGA-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-5","INVNAM":"Dr. NGA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":5.48616,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-30","TRTSDTM":"2020-12-04 03:19:40","TRTEDTM":"2023-12-04 21:19:40","TRT01SDTM":"2020-12-04 03:19:40","TRT01EDTM":"2022-12-04 15:19:40","TRT02SDTM":"2022-12-04 15:19:40","TRT02EDTM":"2023-12-04 21:19:40","AP01SDTM":"2020-12-04 03:19:40","AP01EDTM":"2022-12-04 15:19:40","AP02SDTM":"2022-12-04 15:19:40","AP02EDTM":"2023-12-04 21:19:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-04","EOSDY":1096,"LSTALVDT":"2024-01-02","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7040,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89852,"AVALU":"g/L","BASE2":2.7806,"BASE":2.96904,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11792,"PCHG2":4.2409,"CHG":-0.07052,"PCHG":-2.37509,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-04 03:19:40","ADY":1004,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-5-id-99","SUBJID":"id-99","SITEID":"NGA-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-5","INVNAM":"Dr. NGA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":5.48616,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-30","TRTSDTM":"2020-12-04 03:19:40","TRTEDTM":"2023-12-04 21:19:40","TRT01SDTM":"2020-12-04 03:19:40","TRT01EDTM":"2022-12-04 15:19:40","TRT02SDTM":"2022-12-04 15:19:40","TRT02EDTM":"2023-12-04 21:19:40","AP01SDTM":"2020-12-04 03:19:40","AP01EDTM":"2022-12-04 15:19:40","AP02SDTM":"2022-12-04 15:19:40","AP02EDTM":"2023-12-04 21:19:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-04","EOSDY":1096,"LSTALVDT":"2024-01-02","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5809,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87835,"AVALU":"g/L","BASE2":2.7806,"BASE":2.96904,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09776,"PCHG2":3.51571,"CHG":-0.09068,"PCHG":-3.05424,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-10-14 03:19:40","ADY":1044,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-5-id-99","SUBJID":"id-99","SITEID":"NGA-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-5","INVNAM":"Dr. NGA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":5.48616,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-30","TRTSDTM":"2020-12-04 03:19:40","TRTEDTM":"2023-12-04 21:19:40","TRT01SDTM":"2020-12-04 03:19:40","TRT01EDTM":"2022-12-04 15:19:40","TRT02SDTM":"2022-12-04 15:19:40","TRT02EDTM":"2023-12-04 21:19:40","AP01SDTM":"2020-12-04 03:19:40","AP01EDTM":"2022-12-04 15:19:40","AP02SDTM":"2022-12-04 15:19:40","AP02EDTM":"2023-12-04 21:19:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-04","EOSDY":1096,"LSTALVDT":"2024-01-02","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7644,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04135,"AVALU":"g/L","BASE2":2.7806,"BASE":2.96904,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.26075,"PCHG2":9.37764,"CHG":0.07231,"PCHG":2.43564,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2023-11-23 03:19:40","ADY":1084,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-5-id-99","SUBJID":"id-99","SITEID":"NGA-5","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-5","INVNAM":"Dr. NGA-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Africa","STRATA1":"A","STRATA2":"S2","BMRKR1":5.48616,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-11-30","TRTSDTM":"2020-12-04 03:19:40","TRTEDTM":"2023-12-04 21:19:40","TRT01SDTM":"2020-12-04 03:19:40","TRT01EDTM":"2022-12-04 15:19:40","TRT02SDTM":"2022-12-04 15:19:40","TRT02EDTM":"2023-12-04 21:19:40","AP01SDTM":"2020-12-04 03:19:40","AP01EDTM":"2022-12-04 15:19:40","AP02SDTM":"2022-12-04 15:19:40","AP02EDTM":"2023-12-04 21:19:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-04","EOSDY":1096,"LSTALVDT":"2024-01-02","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2481,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89249,"AVALU":"g/L","BASE2":2.7806,"BASE":2.96904,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11189,"PCHG2":4.02395,"CHG":-0.07655,"PCHG":-2.57826,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-11-24 03:19:40","ADY":1085,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-6-id-363","SUBJID":"id-363","SITEID":"NGA-6","AGE":50,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-6","INVNAM":"Dr. NGA-6 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.17937,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-08 16:56:00","TRTEDTM":"2022-02-18 03:34:30","TRT01SDTM":"2020-04-08 16:56:00","TRT01EDTM":"2021-02-17 21:34:30","TRT02SDTM":"2021-02-17 21:34:30","TRT02EDTM":"2022-02-18 03:34:30","AP01SDTM":"2020-04-08 16:56:00","AP01EDTM":"2021-02-17 21:34:30","AP02SDTM":"2021-02-17 21:34:30","AP02EDTM":"2022-02-18 03:34:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":681,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7308,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.60821,"AVALU":"U/L","BASE2":23.60821,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-24 16:56:00","ADY":16,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-6-id-363","SUBJID":"id-363","SITEID":"NGA-6","AGE":50,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-6","INVNAM":"Dr. NGA-6 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.17937,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-08 16:56:00","TRTEDTM":"2022-02-18 03:34:30","TRT01SDTM":"2020-04-08 16:56:00","TRT01EDTM":"2021-02-17 21:34:30","TRT02SDTM":"2021-02-17 21:34:30","TRT02EDTM":"2022-02-18 03:34:30","AP01SDTM":"2020-04-08 16:56:00","AP01EDTM":"2021-02-17 21:34:30","AP02SDTM":"2021-02-17 21:34:30","AP02EDTM":"2022-02-18 03:34:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":681,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7230,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":39.80834,"AVALU":"U/L","BASE2":23.60821,"BASE":39.80834,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":16.20013,"PCHG2":68.62075,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-31 16:56:00","ADY":145,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-6-id-363","SUBJID":"id-363","SITEID":"NGA-6","AGE":50,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-6","INVNAM":"Dr. NGA-6 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.17937,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-08 16:56:00","TRTEDTM":"2022-02-18 03:34:30","TRT01SDTM":"2020-04-08 16:56:00","TRT01EDTM":"2021-02-17 21:34:30","TRT02SDTM":"2021-02-17 21:34:30","TRT02EDTM":"2022-02-18 03:34:30","AP01SDTM":"2020-04-08 16:56:00","AP01EDTM":"2021-02-17 21:34:30","AP02SDTM":"2021-02-17 21:34:30","AP02EDTM":"2022-02-18 03:34:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":681,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4351,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.28544,"AVALU":"U/L","BASE2":23.60821,"BASE":39.80834,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.67724,"PCHG2":24.04772,"CHG":-10.52289,"PCHG":-26.43389,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-26 16:56:00","ADY":171,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-6-id-363","SUBJID":"id-363","SITEID":"NGA-6","AGE":50,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-6","INVNAM":"Dr. NGA-6 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.17937,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-08 16:56:00","TRTEDTM":"2022-02-18 03:34:30","TRT01SDTM":"2020-04-08 16:56:00","TRT01EDTM":"2021-02-17 21:34:30","TRT02SDTM":"2021-02-17 21:34:30","TRT02EDTM":"2022-02-18 03:34:30","AP01SDTM":"2020-04-08 16:56:00","AP01EDTM":"2021-02-17 21:34:30","AP02SDTM":"2021-02-17 21:34:30","AP02EDTM":"2022-02-18 03:34:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":681,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4619,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.44771,"AVALU":"U/L","BASE2":23.60821,"BASE":39.80834,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.1605,"PCHG2":-51.50961,"CHG":-28.36063,"PCHG":-71.24293,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-30 16:56:00","ADY":175,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-6-id-363","SUBJID":"id-363","SITEID":"NGA-6","AGE":50,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-6","INVNAM":"Dr. NGA-6 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.17937,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-08 16:56:00","TRTEDTM":"2022-02-18 03:34:30","TRT01SDTM":"2020-04-08 16:56:00","TRT01EDTM":"2021-02-17 21:34:30","TRT02SDTM":"2021-02-17 21:34:30","TRT02EDTM":"2022-02-18 03:34:30","AP01SDTM":"2020-04-08 16:56:00","AP01EDTM":"2021-02-17 21:34:30","AP02SDTM":"2021-02-17 21:34:30","AP02EDTM":"2022-02-18 03:34:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":681,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5723,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.83913,"AVALU":"U/L","BASE2":23.60821,"BASE":39.80834,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.23092,"PCHG2":13.68559,"CHG":-12.96921,"PCHG":-32.57913,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-06 16:56:00","ADY":212,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-6-id-363","SUBJID":"id-363","SITEID":"NGA-6","AGE":50,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-6","INVNAM":"Dr. NGA-6 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.17937,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-08 16:56:00","TRTEDTM":"2022-02-18 03:34:30","TRT01SDTM":"2020-04-08 16:56:00","TRT01EDTM":"2021-02-17 21:34:30","TRT02SDTM":"2021-02-17 21:34:30","TRT02EDTM":"2022-02-18 03:34:30","AP01SDTM":"2020-04-08 16:56:00","AP01EDTM":"2021-02-17 21:34:30","AP02SDTM":"2021-02-17 21:34:30","AP02EDTM":"2022-02-18 03:34:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":681,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7061,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.41395,"AVALU":"U/L","BASE2":23.60821,"BASE":39.80834,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.80575,"PCHG2":3.41299,"CHG":-15.39438,"PCHG":-38.67125,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-29 16:56:00","ADY":661,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-6-id-363","SUBJID":"id-363","SITEID":"NGA-6","AGE":50,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-6","INVNAM":"Dr. NGA-6 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.17937,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-08 16:56:00","TRTEDTM":"2022-02-18 03:34:30","TRT01SDTM":"2020-04-08 16:56:00","TRT01EDTM":"2021-02-17 21:34:30","TRT02SDTM":"2021-02-17 21:34:30","TRT02EDTM":"2022-02-18 03:34:30","AP01SDTM":"2020-04-08 16:56:00","AP01EDTM":"2021-02-17 21:34:30","AP02SDTM":"2021-02-17 21:34:30","AP02EDTM":"2022-02-18 03:34:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":681,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1976,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.27725,"AVALU":"U/L","BASE2":23.60821,"BASE":39.80834,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.66904,"PCHG2":28.24882,"CHG":-9.53109,"PCHG":-23.94245,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-07 16:56:00","ADY":670,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-6-id-363","SUBJID":"id-363","SITEID":"NGA-6","AGE":50,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-6","INVNAM":"Dr. NGA-6 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.17937,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-08 16:56:00","TRTEDTM":"2022-02-18 03:34:30","TRT01SDTM":"2020-04-08 16:56:00","TRT01EDTM":"2021-02-17 21:34:30","TRT02SDTM":"2021-02-17 21:34:30","TRT02EDTM":"2022-02-18 03:34:30","AP01SDTM":"2020-04-08 16:56:00","AP01EDTM":"2021-02-17 21:34:30","AP02SDTM":"2021-02-17 21:34:30","AP02EDTM":"2022-02-18 03:34:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":681,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2431,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.59136,"AVALU":"mg/L","BASE2":8.59136,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-24 16:56:00","ADY":16,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-6-id-363","SUBJID":"id-363","SITEID":"NGA-6","AGE":50,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-6","INVNAM":"Dr. NGA-6 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.17937,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-08 16:56:00","TRTEDTM":"2022-02-18 03:34:30","TRT01SDTM":"2020-04-08 16:56:00","TRT01EDTM":"2021-02-17 21:34:30","TRT02SDTM":"2021-02-17 21:34:30","TRT02EDTM":"2022-02-18 03:34:30","AP01SDTM":"2020-04-08 16:56:00","AP01EDTM":"2021-02-17 21:34:30","AP02SDTM":"2021-02-17 21:34:30","AP02EDTM":"2022-02-18 03:34:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":681,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8215,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.96306,"AVALU":"mg/L","BASE2":8.59136,"BASE":8.96306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.3717,"PCHG2":4.32645,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-31 16:56:00","ADY":145,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-6-id-363","SUBJID":"id-363","SITEID":"NGA-6","AGE":50,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-6","INVNAM":"Dr. NGA-6 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.17937,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-08 16:56:00","TRTEDTM":"2022-02-18 03:34:30","TRT01SDTM":"2020-04-08 16:56:00","TRT01EDTM":"2021-02-17 21:34:30","TRT02SDTM":"2021-02-17 21:34:30","TRT02EDTM":"2022-02-18 03:34:30","AP01SDTM":"2020-04-08 16:56:00","AP01EDTM":"2021-02-17 21:34:30","AP02SDTM":"2021-02-17 21:34:30","AP02EDTM":"2022-02-18 03:34:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":681,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":284,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.18086,"AVALU":"mg/L","BASE2":8.59136,"BASE":8.96306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.5895,"PCHG2":6.86153,"CHG":0.2178,"PCHG":2.42995,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-26 16:56:00","ADY":171,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-6-id-363","SUBJID":"id-363","SITEID":"NGA-6","AGE":50,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-6","INVNAM":"Dr. NGA-6 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.17937,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-08 16:56:00","TRTEDTM":"2022-02-18 03:34:30","TRT01SDTM":"2020-04-08 16:56:00","TRT01EDTM":"2021-02-17 21:34:30","TRT02SDTM":"2021-02-17 21:34:30","TRT02EDTM":"2022-02-18 03:34:30","AP01SDTM":"2020-04-08 16:56:00","AP01EDTM":"2021-02-17 21:34:30","AP02SDTM":"2021-02-17 21:34:30","AP02EDTM":"2022-02-18 03:34:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":681,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1749,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.16477,"AVALU":"mg/L","BASE2":8.59136,"BASE":8.96306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.42659,"PCHG2":-16.60498,"CHG":-1.79829,"PCHG":-20.0634,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-09-30 16:56:00","ADY":175,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-6-id-363","SUBJID":"id-363","SITEID":"NGA-6","AGE":50,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-6","INVNAM":"Dr. NGA-6 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.17937,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-08 16:56:00","TRTEDTM":"2022-02-18 03:34:30","TRT01SDTM":"2020-04-08 16:56:00","TRT01EDTM":"2021-02-17 21:34:30","TRT02SDTM":"2021-02-17 21:34:30","TRT02EDTM":"2022-02-18 03:34:30","AP01SDTM":"2020-04-08 16:56:00","AP01EDTM":"2021-02-17 21:34:30","AP02SDTM":"2021-02-17 21:34:30","AP02EDTM":"2022-02-18 03:34:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":681,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2924,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.23673,"AVALU":"mg/L","BASE2":8.59136,"BASE":8.96306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.35463,"PCHG2":-4.1278,"CHG":-0.72634,"PCHG":-8.10365,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-06 16:56:00","ADY":212,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-6-id-363","SUBJID":"id-363","SITEID":"NGA-6","AGE":50,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-6","INVNAM":"Dr. NGA-6 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.17937,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-08 16:56:00","TRTEDTM":"2022-02-18 03:34:30","TRT01SDTM":"2020-04-08 16:56:00","TRT01EDTM":"2021-02-17 21:34:30","TRT02SDTM":"2021-02-17 21:34:30","TRT02EDTM":"2022-02-18 03:34:30","AP01SDTM":"2020-04-08 16:56:00","AP01EDTM":"2021-02-17 21:34:30","AP02SDTM":"2021-02-17 21:34:30","AP02EDTM":"2022-02-18 03:34:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":681,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2992,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.11843,"AVALU":"mg/L","BASE2":8.59136,"BASE":8.96306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.47293,"PCHG2":-5.5047,"CHG":-0.84463,"PCHG":-9.42345,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-29 16:56:00","ADY":661,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-6-id-363","SUBJID":"id-363","SITEID":"NGA-6","AGE":50,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-6","INVNAM":"Dr. NGA-6 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.17937,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-08 16:56:00","TRTEDTM":"2022-02-18 03:34:30","TRT01SDTM":"2020-04-08 16:56:00","TRT01EDTM":"2021-02-17 21:34:30","TRT02SDTM":"2021-02-17 21:34:30","TRT02EDTM":"2022-02-18 03:34:30","AP01SDTM":"2020-04-08 16:56:00","AP01EDTM":"2021-02-17 21:34:30","AP02SDTM":"2021-02-17 21:34:30","AP02EDTM":"2022-02-18 03:34:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":681,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7104,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.93137,"AVALU":"mg/L","BASE2":8.59136,"BASE":8.96306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.34001,"PCHG2":3.95759,"CHG":-0.03169,"PCHG":-0.35357,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-07 16:56:00","ADY":670,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-6-id-363","SUBJID":"id-363","SITEID":"NGA-6","AGE":50,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-6","INVNAM":"Dr. NGA-6 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.17937,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-08 16:56:00","TRTEDTM":"2022-02-18 03:34:30","TRT01SDTM":"2020-04-08 16:56:00","TRT01EDTM":"2021-02-17 21:34:30","TRT02SDTM":"2021-02-17 21:34:30","TRT02EDTM":"2022-02-18 03:34:30","AP01SDTM":"2020-04-08 16:56:00","AP01EDTM":"2021-02-17 21:34:30","AP02SDTM":"2021-02-17 21:34:30","AP02EDTM":"2022-02-18 03:34:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":681,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2368,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95126,"AVALU":"g/L","BASE2":2.95126,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-24 16:56:00","ADY":16,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-6-id-363","SUBJID":"id-363","SITEID":"NGA-6","AGE":50,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-6","INVNAM":"Dr. NGA-6 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.17937,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-08 16:56:00","TRTEDTM":"2022-02-18 03:34:30","TRT01SDTM":"2020-04-08 16:56:00","TRT01EDTM":"2021-02-17 21:34:30","TRT02SDTM":"2021-02-17 21:34:30","TRT02EDTM":"2022-02-18 03:34:30","AP01SDTM":"2020-04-08 16:56:00","AP01EDTM":"2021-02-17 21:34:30","AP02SDTM":"2021-02-17 21:34:30","AP02EDTM":"2022-02-18 03:34:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":681,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4982,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88525,"AVALU":"g/L","BASE2":2.95126,"BASE":2.88525,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.06602,"PCHG2":-2.23687,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-31 16:56:00","ADY":145,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-6-id-363","SUBJID":"id-363","SITEID":"NGA-6","AGE":50,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-6","INVNAM":"Dr. NGA-6 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.17937,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-08 16:56:00","TRTEDTM":"2022-02-18 03:34:30","TRT01SDTM":"2020-04-08 16:56:00","TRT01EDTM":"2021-02-17 21:34:30","TRT02SDTM":"2021-02-17 21:34:30","TRT02EDTM":"2022-02-18 03:34:30","AP01SDTM":"2020-04-08 16:56:00","AP01EDTM":"2021-02-17 21:34:30","AP02SDTM":"2021-02-17 21:34:30","AP02EDTM":"2022-02-18 03:34:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":681,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":89,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81938,"AVALU":"g/L","BASE2":2.95126,"BASE":2.88525,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13188,"PCHG2":-4.46875,"CHG":-0.06587,"PCHG":-2.28295,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-26 16:56:00","ADY":171,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-6-id-363","SUBJID":"id-363","SITEID":"NGA-6","AGE":50,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-6","INVNAM":"Dr. NGA-6 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.17937,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-08 16:56:00","TRTEDTM":"2022-02-18 03:34:30","TRT01SDTM":"2020-04-08 16:56:00","TRT01EDTM":"2021-02-17 21:34:30","TRT02SDTM":"2021-02-17 21:34:30","TRT02EDTM":"2022-02-18 03:34:30","AP01SDTM":"2020-04-08 16:56:00","AP01EDTM":"2021-02-17 21:34:30","AP02SDTM":"2021-02-17 21:34:30","AP02EDTM":"2022-02-18 03:34:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":681,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8118,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79079,"AVALU":"g/L","BASE2":2.95126,"BASE":2.88525,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16047,"PCHG2":-5.43747,"CHG":-0.09446,"PCHG":-3.27383,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-30 16:56:00","ADY":175,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-6-id-363","SUBJID":"id-363","SITEID":"NGA-6","AGE":50,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-6","INVNAM":"Dr. NGA-6 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.17937,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-08 16:56:00","TRTEDTM":"2022-02-18 03:34:30","TRT01SDTM":"2020-04-08 16:56:00","TRT01EDTM":"2021-02-17 21:34:30","TRT02SDTM":"2021-02-17 21:34:30","TRT02EDTM":"2022-02-18 03:34:30","AP01SDTM":"2020-04-08 16:56:00","AP01EDTM":"2021-02-17 21:34:30","AP02SDTM":"2021-02-17 21:34:30","AP02EDTM":"2022-02-18 03:34:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":681,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6593,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00359,"AVALU":"g/L","BASE2":2.95126,"BASE":2.88525,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05233,"PCHG2":1.77319,"CHG":0.11835,"PCHG":4.10182,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-11-06 16:56:00","ADY":212,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-6-id-363","SUBJID":"id-363","SITEID":"NGA-6","AGE":50,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-6","INVNAM":"Dr. NGA-6 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.17937,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-08 16:56:00","TRTEDTM":"2022-02-18 03:34:30","TRT01SDTM":"2020-04-08 16:56:00","TRT01EDTM":"2021-02-17 21:34:30","TRT02SDTM":"2021-02-17 21:34:30","TRT02EDTM":"2022-02-18 03:34:30","AP01SDTM":"2020-04-08 16:56:00","AP01EDTM":"2021-02-17 21:34:30","AP02SDTM":"2021-02-17 21:34:30","AP02EDTM":"2022-02-18 03:34:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":681,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2841,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89117,"AVALU":"g/L","BASE2":2.95126,"BASE":2.88525,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0601,"PCHG2":-2.03628,"CHG":0.00592,"PCHG":0.20518,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-29 16:56:00","ADY":661,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-NGA-6-id-363","SUBJID":"id-363","SITEID":"NGA-6","AGE":50,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"NGA","DTHFL":"N","INVID":"INV ID NGA-6","INVNAM":"Dr. NGA-6 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Africa","STRATA1":"C","STRATA2":"S2","BMRKR1":4.17937,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-08 16:56:00","TRTEDTM":"2022-02-18 03:34:30","TRT01SDTM":"2020-04-08 16:56:00","TRT01EDTM":"2021-02-17 21:34:30","TRT02SDTM":"2021-02-17 21:34:30","TRT02EDTM":"2022-02-18 03:34:30","AP01SDTM":"2020-04-08 16:56:00","AP01EDTM":"2021-02-17 21:34:30","AP02SDTM":"2021-02-17 21:34:30","AP02EDTM":"2022-02-18 03:34:30","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":681,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-16","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1599,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93693,"AVALU":"g/L","BASE2":2.95126,"BASE":2.88525,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01433,"PCHG2":-0.48551,"CHG":0.05169,"PCHG":1.79144,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-07 16:56:00","ADY":670,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-112","SUBJID":"id-112","SITEID":"PAK-1","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":14.23741,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-26 06:22:25","TRT01SDTM":"2019-12-26 06:22:25","AP01SDTM":"2019-12-26 06:22:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5800,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.61353,"AVALU":"U/L","BASE2":15.61353,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-07-01 06:22:25","ADY":188,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-112","SUBJID":"id-112","SITEID":"PAK-1","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":14.23741,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-26 06:22:25","TRT01SDTM":"2019-12-26 06:22:25","AP01SDTM":"2019-12-26 06:22:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4924,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.93832,"AVALU":"U/L","BASE2":15.61353,"BASE":4.93832,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-10.67521,"PCHG2":-68.37156,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2020-07-06 06:22:25","ADY":193,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-112","SUBJID":"id-112","SITEID":"PAK-1","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":14.23741,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-26 06:22:25","TRT01SDTM":"2019-12-26 06:22:25","AP01SDTM":"2019-12-26 06:22:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2202,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.10879,"AVALU":"U/L","BASE2":15.61353,"BASE":4.93832,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.49526,"PCHG2":35.19551,"CHG":16.17048,"PCHG":327.44922,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-08-24 06:22:25","ADY":242,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-112","SUBJID":"id-112","SITEID":"PAK-1","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":14.23741,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-26 06:22:25","TRT01SDTM":"2019-12-26 06:22:25","AP01SDTM":"2019-12-26 06:22:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1514,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.85622,"AVALU":"U/L","BASE2":15.61353,"BASE":4.93832,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.24269,"PCHG2":7.95905,"CHG":11.9179,"PCHG":241.33538,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-02-13 06:22:25","ADY":415,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-112","SUBJID":"id-112","SITEID":"PAK-1","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":14.23741,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-26 06:22:25","TRT01SDTM":"2019-12-26 06:22:25","AP01SDTM":"2019-12-26 06:22:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2062,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.32992,"AVALU":"U/L","BASE2":15.61353,"BASE":4.93832,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.71639,"PCHG2":68.63527,"CHG":21.3916,"PCHG":433.17609,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-02-23 06:22:25","ADY":425,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-112","SUBJID":"id-112","SITEID":"PAK-1","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":14.23741,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-26 06:22:25","TRT01SDTM":"2019-12-26 06:22:25","AP01SDTM":"2019-12-26 06:22:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8137,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.36835,"AVALU":"U/L","BASE2":15.61353,"BASE":4.93832,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.24518,"PCHG2":-27.18911,"CHG":6.43003,"PCHG":130.20704,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-03-19 06:22:25","ADY":449,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-112","SUBJID":"id-112","SITEID":"PAK-1","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":14.23741,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-26 06:22:25","TRT01SDTM":"2019-12-26 06:22:25","AP01SDTM":"2019-12-26 06:22:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1457,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.86313,"AVALU":"U/L","BASE2":15.61353,"BASE":4.93832,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.7504,"PCHG2":-30.42492,"CHG":5.92481,"PCHG":119.97634,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-09-18 06:22:25","ADY":632,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-112","SUBJID":"id-112","SITEID":"PAK-1","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":14.23741,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-26 06:22:25","TRT01SDTM":"2019-12-26 06:22:25","AP01SDTM":"2019-12-26 06:22:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":491,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.30774,"AVALU":"mg/L","BASE2":9.30774,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-01 06:22:25","ADY":188,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-112","SUBJID":"id-112","SITEID":"PAK-1","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":14.23741,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-26 06:22:25","TRT01SDTM":"2019-12-26 06:22:25","AP01SDTM":"2019-12-26 06:22:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1303,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.5019,"AVALU":"mg/L","BASE2":9.30774,"BASE":8.5019,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.80584,"PCHG2":-8.65778,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-06 06:22:25","ADY":193,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-112","SUBJID":"id-112","SITEID":"PAK-1","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":14.23741,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-26 06:22:25","TRT01SDTM":"2019-12-26 06:22:25","AP01SDTM":"2019-12-26 06:22:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3280,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.98146,"AVALU":"mg/L","BASE2":9.30774,"BASE":8.5019,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.32629,"PCHG2":-14.24927,"CHG":-0.52044,"PCHG":-6.12148,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-08-24 06:22:25","ADY":242,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-112","SUBJID":"id-112","SITEID":"PAK-1","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":14.23741,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-26 06:22:25","TRT01SDTM":"2019-12-26 06:22:25","AP01SDTM":"2019-12-26 06:22:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7072,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.55146,"AVALU":"mg/L","BASE2":9.30774,"BASE":8.5019,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.75628,"PCHG2":-8.12528,"CHG":0.04956,"PCHG":0.58297,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-13 06:22:25","ADY":415,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-112","SUBJID":"id-112","SITEID":"PAK-1","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":14.23741,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-26 06:22:25","TRT01SDTM":"2019-12-26 06:22:25","AP01SDTM":"2019-12-26 06:22:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":820,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.77436,"AVALU":"mg/L","BASE2":9.30774,"BASE":8.5019,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.46662,"PCHG2":5.01321,"CHG":1.27246,"PCHG":14.96677,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-23 06:22:25","ADY":425,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-112","SUBJID":"id-112","SITEID":"PAK-1","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":14.23741,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-26 06:22:25","TRT01SDTM":"2019-12-26 06:22:25","AP01SDTM":"2019-12-26 06:22:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2082,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.37435,"AVALU":"mg/L","BASE2":9.30774,"BASE":8.5019,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06661,"PCHG2":0.71559,"CHG":0.87245,"PCHG":10.26181,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-19 06:22:25","ADY":449,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-112","SUBJID":"id-112","SITEID":"PAK-1","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":14.23741,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-26 06:22:25","TRT01SDTM":"2019-12-26 06:22:25","AP01SDTM":"2019-12-26 06:22:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7348,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.65036,"AVALU":"mg/L","BASE2":9.30774,"BASE":8.5019,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.34262,"PCHG2":3.68103,"CHG":1.14846,"PCHG":13.50833,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-18 06:22:25","ADY":632,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-112","SUBJID":"id-112","SITEID":"PAK-1","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":14.23741,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-26 06:22:25","TRT01SDTM":"2019-12-26 06:22:25","AP01SDTM":"2019-12-26 06:22:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3793,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74775,"AVALU":"g/L","BASE2":2.74775,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-01 06:22:25","ADY":188,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-112","SUBJID":"id-112","SITEID":"PAK-1","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":14.23741,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-26 06:22:25","TRT01SDTM":"2019-12-26 06:22:25","AP01SDTM":"2019-12-26 06:22:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7568,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.68458,"AVALU":"g/L","BASE2":2.74775,"BASE":2.68458,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.06316,"PCHG2":-2.29874,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-06 06:22:25","ADY":193,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-112","SUBJID":"id-112","SITEID":"PAK-1","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":14.23741,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-26 06:22:25","TRT01SDTM":"2019-12-26 06:22:25","AP01SDTM":"2019-12-26 06:22:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5501,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93116,"AVALU":"g/L","BASE2":2.74775,"BASE":2.68458,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18341,"PCHG2":6.67502,"CHG":0.24658,"PCHG":9.18489,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-24 06:22:25","ADY":242,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-112","SUBJID":"id-112","SITEID":"PAK-1","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":14.23741,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-26 06:22:25","TRT01SDTM":"2019-12-26 06:22:25","AP01SDTM":"2019-12-26 06:22:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1532,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8824,"AVALU":"g/L","BASE2":2.74775,"BASE":2.68458,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13465,"PCHG2":4.90053,"CHG":0.19782,"PCHG":7.36865,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-13 06:22:25","ADY":415,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-112","SUBJID":"id-112","SITEID":"PAK-1","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":14.23741,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-26 06:22:25","TRT01SDTM":"2019-12-26 06:22:25","AP01SDTM":"2019-12-26 06:22:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1825,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90712,"AVALU":"g/L","BASE2":2.74775,"BASE":2.68458,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15937,"PCHG2":5.80003,"CHG":0.22253,"PCHG":8.28932,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-23 06:22:25","ADY":425,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-112","SUBJID":"id-112","SITEID":"PAK-1","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":14.23741,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-26 06:22:25","TRT01SDTM":"2019-12-26 06:22:25","AP01SDTM":"2019-12-26 06:22:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5071,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9294,"AVALU":"g/L","BASE2":2.74775,"BASE":2.68458,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18165,"PCHG2":6.61104,"CHG":0.24482,"PCHG":9.11941,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-19 06:22:25","ADY":449,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-112","SUBJID":"id-112","SITEID":"PAK-1","AGE":44,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":14.23741,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-26 06:22:25","TRT01SDTM":"2019-12-26 06:22:25","AP01SDTM":"2019-12-26 06:22:25","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4580,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0388,"AVALU":"g/L","BASE2":2.74775,"BASE":2.68458,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.29105,"PCHG2":10.5924,"CHG":0.35422,"PCHG":13.19444,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-09-18 06:22:25","ADY":632,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-125","SUBJID":"id-125","SITEID":"PAK-1","AGE":49,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.63963,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-09","TRTSDTM":"2020-11-11 10:40:21","TRTEDTM":"2023-11-12 04:40:21","TRT01SDTM":"2020-11-11 10:40:21","TRT01EDTM":"2022-11-11 22:40:21","TRT02SDTM":"2022-11-11 22:40:21","TRT02EDTM":"2023-11-12 04:40:21","AP01SDTM":"2020-11-11 10:40:21","AP01EDTM":"2022-11-11 22:40:21","AP02SDTM":"2022-11-11 22:40:21","AP02EDTM":"2023-11-12 04:40:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-12","EOSDY":1096,"LSTALVDT":"2023-12-04","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2363,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.9115,"AVALU":"U/L","BASE2":3.9115,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-09-23 10:40:21","ADY":316,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-125","SUBJID":"id-125","SITEID":"PAK-1","AGE":49,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.63963,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-09","TRTSDTM":"2020-11-11 10:40:21","TRTEDTM":"2023-11-12 04:40:21","TRT01SDTM":"2020-11-11 10:40:21","TRT01EDTM":"2022-11-11 22:40:21","TRT02SDTM":"2022-11-11 22:40:21","TRT02EDTM":"2023-11-12 04:40:21","AP01SDTM":"2020-11-11 10:40:21","AP01EDTM":"2022-11-11 22:40:21","AP02SDTM":"2022-11-11 22:40:21","AP02EDTM":"2023-11-12 04:40:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-12","EOSDY":1096,"LSTALVDT":"2023-12-04","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":795,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.775,"AVALU":"U/L","BASE2":3.9115,"BASE":17.775,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":13.8635,"PCHG2":354.42975,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-26 10:40:21","ADY":380,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-125","SUBJID":"id-125","SITEID":"PAK-1","AGE":49,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.63963,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-09","TRTSDTM":"2020-11-11 10:40:21","TRTEDTM":"2023-11-12 04:40:21","TRT01SDTM":"2020-11-11 10:40:21","TRT01EDTM":"2022-11-11 22:40:21","TRT02SDTM":"2022-11-11 22:40:21","TRT02EDTM":"2023-11-12 04:40:21","AP01SDTM":"2020-11-11 10:40:21","AP01EDTM":"2022-11-11 22:40:21","AP02SDTM":"2022-11-11 22:40:21","AP02EDTM":"2023-11-12 04:40:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-12","EOSDY":1096,"LSTALVDT":"2023-12-04","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1786,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.02938,"AVALU":"U/L","BASE2":3.9115,"BASE":17.775,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.11788,"PCHG2":258.67041,"CHG":-3.74562,"PCHG":-21.07242,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-06 10:40:21","ADY":602,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-125","SUBJID":"id-125","SITEID":"PAK-1","AGE":49,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.63963,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-09","TRTSDTM":"2020-11-11 10:40:21","TRTEDTM":"2023-11-12 04:40:21","TRT01SDTM":"2020-11-11 10:40:21","TRT01EDTM":"2022-11-11 22:40:21","TRT02SDTM":"2022-11-11 22:40:21","TRT02EDTM":"2023-11-12 04:40:21","AP01SDTM":"2020-11-11 10:40:21","AP01EDTM":"2022-11-11 22:40:21","AP02SDTM":"2022-11-11 22:40:21","AP02EDTM":"2023-11-12 04:40:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-12","EOSDY":1096,"LSTALVDT":"2023-12-04","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4509,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.06155,"AVALU":"U/L","BASE2":3.9115,"BASE":17.775,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.15005,"PCHG2":464.01823,"CHG":4.28655,"PCHG":24.1156,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-30 10:40:21","ADY":991,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-125","SUBJID":"id-125","SITEID":"PAK-1","AGE":49,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.63963,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-09","TRTSDTM":"2020-11-11 10:40:21","TRTEDTM":"2023-11-12 04:40:21","TRT01SDTM":"2020-11-11 10:40:21","TRT01EDTM":"2022-11-11 22:40:21","TRT02SDTM":"2022-11-11 22:40:21","TRT02EDTM":"2023-11-12 04:40:21","AP01SDTM":"2020-11-11 10:40:21","AP01EDTM":"2022-11-11 22:40:21","AP02SDTM":"2022-11-11 22:40:21","AP02EDTM":"2023-11-12 04:40:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-12","EOSDY":1096,"LSTALVDT":"2023-12-04","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2550,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.23512,"AVALU":"U/L","BASE2":3.9115,"BASE":17.775,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":17.32363,"PCHG2":442.89016,"CHG":3.46012,"PCHG":19.46624,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-12 10:40:21","ADY":1004,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-125","SUBJID":"id-125","SITEID":"PAK-1","AGE":49,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.63963,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-09","TRTSDTM":"2020-11-11 10:40:21","TRTEDTM":"2023-11-12 04:40:21","TRT01SDTM":"2020-11-11 10:40:21","TRT01EDTM":"2022-11-11 22:40:21","TRT02SDTM":"2022-11-11 22:40:21","TRT02EDTM":"2023-11-12 04:40:21","AP01SDTM":"2020-11-11 10:40:21","AP01EDTM":"2022-11-11 22:40:21","AP02SDTM":"2022-11-11 22:40:21","AP02EDTM":"2023-11-12 04:40:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-12","EOSDY":1096,"LSTALVDT":"2023-12-04","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8373,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.79426,"AVALU":"U/L","BASE2":3.9115,"BASE":17.775,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.88277,"PCHG2":201.52818,"CHG":-5.98074,"PCHG":-33.64691,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-16 10:40:21","ADY":1008,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-125","SUBJID":"id-125","SITEID":"PAK-1","AGE":49,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.63963,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-09","TRTSDTM":"2020-11-11 10:40:21","TRTEDTM":"2023-11-12 04:40:21","TRT01SDTM":"2020-11-11 10:40:21","TRT01EDTM":"2022-11-11 22:40:21","TRT02SDTM":"2022-11-11 22:40:21","TRT02EDTM":"2023-11-12 04:40:21","AP01SDTM":"2020-11-11 10:40:21","AP01EDTM":"2022-11-11 22:40:21","AP02SDTM":"2022-11-11 22:40:21","AP02EDTM":"2023-11-12 04:40:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-12","EOSDY":1096,"LSTALVDT":"2023-12-04","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3516,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":37.46246,"AVALU":"U/L","BASE2":3.9115,"BASE":17.775,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":33.55097,"PCHG2":857.75293,"CHG":19.68746,"PCHG":110.75929,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-27 10:40:21","ADY":1050,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-125","SUBJID":"id-125","SITEID":"PAK-1","AGE":49,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.63963,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-09","TRTSDTM":"2020-11-11 10:40:21","TRTEDTM":"2023-11-12 04:40:21","TRT01SDTM":"2020-11-11 10:40:21","TRT01EDTM":"2022-11-11 22:40:21","TRT02SDTM":"2022-11-11 22:40:21","TRT02EDTM":"2023-11-12 04:40:21","AP01SDTM":"2020-11-11 10:40:21","AP01EDTM":"2022-11-11 22:40:21","AP02SDTM":"2022-11-11 22:40:21","AP02EDTM":"2023-11-12 04:40:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-12","EOSDY":1096,"LSTALVDT":"2023-12-04","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7923,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.96479,"AVALU":"mg/L","BASE2":7.96479,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-09-23 10:40:21","ADY":316,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-125","SUBJID":"id-125","SITEID":"PAK-1","AGE":49,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.63963,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-09","TRTSDTM":"2020-11-11 10:40:21","TRTEDTM":"2023-11-12 04:40:21","TRT01SDTM":"2020-11-11 10:40:21","TRT01EDTM":"2022-11-11 22:40:21","TRT02SDTM":"2022-11-11 22:40:21","TRT02EDTM":"2023-11-12 04:40:21","AP01SDTM":"2020-11-11 10:40:21","AP01EDTM":"2022-11-11 22:40:21","AP02SDTM":"2022-11-11 22:40:21","AP02EDTM":"2023-11-12 04:40:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-12","EOSDY":1096,"LSTALVDT":"2023-12-04","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1307,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.77553,"AVALU":"mg/L","BASE2":7.96479,"BASE":8.77553,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.81074,"PCHG2":10.17909,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-26 10:40:21","ADY":380,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-125","SUBJID":"id-125","SITEID":"PAK-1","AGE":49,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.63963,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-09","TRTSDTM":"2020-11-11 10:40:21","TRTEDTM":"2023-11-12 04:40:21","TRT01SDTM":"2020-11-11 10:40:21","TRT01EDTM":"2022-11-11 22:40:21","TRT02SDTM":"2022-11-11 22:40:21","TRT02EDTM":"2023-11-12 04:40:21","AP01SDTM":"2020-11-11 10:40:21","AP01EDTM":"2022-11-11 22:40:21","AP02SDTM":"2022-11-11 22:40:21","AP02EDTM":"2023-11-12 04:40:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-12","EOSDY":1096,"LSTALVDT":"2023-12-04","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4895,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.63959,"AVALU":"mg/L","BASE2":7.96479,"BASE":8.77553,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.3252,"PCHG2":-4.08301,"CHG":-1.13595,"PCHG":-12.94447,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-07-06 10:40:21","ADY":602,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-125","SUBJID":"id-125","SITEID":"PAK-1","AGE":49,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.63963,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-09","TRTSDTM":"2020-11-11 10:40:21","TRTEDTM":"2023-11-12 04:40:21","TRT01SDTM":"2020-11-11 10:40:21","TRT01EDTM":"2022-11-11 22:40:21","TRT02SDTM":"2022-11-11 22:40:21","TRT02EDTM":"2023-11-12 04:40:21","AP01SDTM":"2020-11-11 10:40:21","AP01EDTM":"2022-11-11 22:40:21","AP02SDTM":"2022-11-11 22:40:21","AP02EDTM":"2023-11-12 04:40:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-12","EOSDY":1096,"LSTALVDT":"2023-12-04","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6051,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.30889,"AVALU":"mg/L","BASE2":7.96479,"BASE":8.77553,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.6559,"PCHG2":-8.235,"CHG":-1.46664,"PCHG":-16.71288,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2023-07-30 10:40:21","ADY":991,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-125","SUBJID":"id-125","SITEID":"PAK-1","AGE":49,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.63963,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-09","TRTSDTM":"2020-11-11 10:40:21","TRTEDTM":"2023-11-12 04:40:21","TRT01SDTM":"2020-11-11 10:40:21","TRT01EDTM":"2022-11-11 22:40:21","TRT02SDTM":"2022-11-11 22:40:21","TRT02EDTM":"2023-11-12 04:40:21","AP01SDTM":"2020-11-11 10:40:21","AP01EDTM":"2022-11-11 22:40:21","AP02SDTM":"2022-11-11 22:40:21","AP02EDTM":"2023-11-12 04:40:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-12","EOSDY":1096,"LSTALVDT":"2023-12-04","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2421,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.90233,"AVALU":"mg/L","BASE2":7.96479,"BASE":8.77553,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.93754,"PCHG2":11.77104,"CHG":0.12679,"PCHG":1.44487,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-12 10:40:21","ADY":1004,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-125","SUBJID":"id-125","SITEID":"PAK-1","AGE":49,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.63963,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-09","TRTSDTM":"2020-11-11 10:40:21","TRTEDTM":"2023-11-12 04:40:21","TRT01SDTM":"2020-11-11 10:40:21","TRT01EDTM":"2022-11-11 22:40:21","TRT02SDTM":"2022-11-11 22:40:21","TRT02EDTM":"2023-11-12 04:40:21","AP01SDTM":"2020-11-11 10:40:21","AP01EDTM":"2022-11-11 22:40:21","AP02SDTM":"2022-11-11 22:40:21","AP02EDTM":"2023-11-12 04:40:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-12","EOSDY":1096,"LSTALVDT":"2023-12-04","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2552,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.38426,"AVALU":"mg/L","BASE2":7.96479,"BASE":8.77553,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.41947,"PCHG2":30.37704,"CHG":1.60872,"PCHG":18.33193,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2023-08-16 10:40:21","ADY":1008,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-125","SUBJID":"id-125","SITEID":"PAK-1","AGE":49,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.63963,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-09","TRTSDTM":"2020-11-11 10:40:21","TRTEDTM":"2023-11-12 04:40:21","TRT01SDTM":"2020-11-11 10:40:21","TRT01EDTM":"2022-11-11 22:40:21","TRT02SDTM":"2022-11-11 22:40:21","TRT02EDTM":"2023-11-12 04:40:21","AP01SDTM":"2020-11-11 10:40:21","AP01EDTM":"2022-11-11 22:40:21","AP02SDTM":"2022-11-11 22:40:21","AP02EDTM":"2023-11-12 04:40:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-12","EOSDY":1096,"LSTALVDT":"2023-12-04","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7083,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.55682,"AVALU":"mg/L","BASE2":7.96479,"BASE":8.77553,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.59203,"PCHG2":45.09888,"CHG":2.78129,"PCHG":31.69366,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2023-09-27 10:40:21","ADY":1050,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-125","SUBJID":"id-125","SITEID":"PAK-1","AGE":49,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.63963,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-09","TRTSDTM":"2020-11-11 10:40:21","TRTEDTM":"2023-11-12 04:40:21","TRT01SDTM":"2020-11-11 10:40:21","TRT01EDTM":"2022-11-11 22:40:21","TRT02SDTM":"2022-11-11 22:40:21","TRT02EDTM":"2023-11-12 04:40:21","AP01SDTM":"2020-11-11 10:40:21","AP01EDTM":"2022-11-11 22:40:21","AP02SDTM":"2022-11-11 22:40:21","AP02EDTM":"2023-11-12 04:40:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-12","EOSDY":1096,"LSTALVDT":"2023-12-04","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1557,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87355,"AVALU":"g/L","BASE2":2.87355,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-23 10:40:21","ADY":316,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-125","SUBJID":"id-125","SITEID":"PAK-1","AGE":49,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.63963,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-09","TRTSDTM":"2020-11-11 10:40:21","TRTEDTM":"2023-11-12 04:40:21","TRT01SDTM":"2020-11-11 10:40:21","TRT01EDTM":"2022-11-11 22:40:21","TRT02SDTM":"2022-11-11 22:40:21","TRT02EDTM":"2023-11-12 04:40:21","AP01SDTM":"2020-11-11 10:40:21","AP01EDTM":"2022-11-11 22:40:21","AP02SDTM":"2022-11-11 22:40:21","AP02EDTM":"2023-11-12 04:40:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-12","EOSDY":1096,"LSTALVDT":"2023-12-04","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2001,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82056,"AVALU":"g/L","BASE2":2.87355,"BASE":2.82056,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.053,"PCHG2":-1.84429,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-26 10:40:21","ADY":380,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-125","SUBJID":"id-125","SITEID":"PAK-1","AGE":49,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.63963,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-09","TRTSDTM":"2020-11-11 10:40:21","TRTEDTM":"2023-11-12 04:40:21","TRT01SDTM":"2020-11-11 10:40:21","TRT01EDTM":"2022-11-11 22:40:21","TRT02SDTM":"2022-11-11 22:40:21","TRT02EDTM":"2023-11-12 04:40:21","AP01SDTM":"2020-11-11 10:40:21","AP01EDTM":"2022-11-11 22:40:21","AP02SDTM":"2022-11-11 22:40:21","AP02EDTM":"2023-11-12 04:40:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-12","EOSDY":1096,"LSTALVDT":"2023-12-04","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5974,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03718,"AVALU":"g/L","BASE2":2.87355,"BASE":2.82056,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16363,"PCHG2":5.69442,"CHG":0.21663,"PCHG":7.68036,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-07-06 10:40:21","ADY":602,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-125","SUBJID":"id-125","SITEID":"PAK-1","AGE":49,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.63963,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-09","TRTSDTM":"2020-11-11 10:40:21","TRTEDTM":"2023-11-12 04:40:21","TRT01SDTM":"2020-11-11 10:40:21","TRT01EDTM":"2022-11-11 22:40:21","TRT02SDTM":"2022-11-11 22:40:21","TRT02EDTM":"2023-11-12 04:40:21","AP01SDTM":"2020-11-11 10:40:21","AP01EDTM":"2022-11-11 22:40:21","AP02SDTM":"2022-11-11 22:40:21","AP02EDTM":"2023-11-12 04:40:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-12","EOSDY":1096,"LSTALVDT":"2023-12-04","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1224,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84006,"AVALU":"g/L","BASE2":2.87355,"BASE":2.82056,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03349,"PCHG2":-1.16558,"CHG":0.0195,"PCHG":0.69146,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-30 10:40:21","ADY":991,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-125","SUBJID":"id-125","SITEID":"PAK-1","AGE":49,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.63963,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-09","TRTSDTM":"2020-11-11 10:40:21","TRTEDTM":"2023-11-12 04:40:21","TRT01SDTM":"2020-11-11 10:40:21","TRT01EDTM":"2022-11-11 22:40:21","TRT02SDTM":"2022-11-11 22:40:21","TRT02EDTM":"2023-11-12 04:40:21","AP01SDTM":"2020-11-11 10:40:21","AP01EDTM":"2022-11-11 22:40:21","AP02SDTM":"2022-11-11 22:40:21","AP02EDTM":"2023-11-12 04:40:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-12","EOSDY":1096,"LSTALVDT":"2023-12-04","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1772,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84122,"AVALU":"g/L","BASE2":2.87355,"BASE":2.82056,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03233,"PCHG2":-1.12511,"CHG":0.02067,"PCHG":0.73269,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-12 10:40:21","ADY":1004,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-125","SUBJID":"id-125","SITEID":"PAK-1","AGE":49,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.63963,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-09","TRTSDTM":"2020-11-11 10:40:21","TRTEDTM":"2023-11-12 04:40:21","TRT01SDTM":"2020-11-11 10:40:21","TRT01EDTM":"2022-11-11 22:40:21","TRT02SDTM":"2022-11-11 22:40:21","TRT02EDTM":"2023-11-12 04:40:21","AP01SDTM":"2020-11-11 10:40:21","AP01EDTM":"2022-11-11 22:40:21","AP02SDTM":"2022-11-11 22:40:21","AP02EDTM":"2023-11-12 04:40:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-12","EOSDY":1096,"LSTALVDT":"2023-12-04","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1173,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87179,"AVALU":"g/L","BASE2":2.87355,"BASE":2.82056,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00176,"PCHG2":-0.06129,"CHG":0.05124,"PCHG":1.8165,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-16 10:40:21","ADY":1008,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-125","SUBJID":"id-125","SITEID":"PAK-1","AGE":49,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":6.63963,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-09","TRTSDTM":"2020-11-11 10:40:21","TRTEDTM":"2023-11-12 04:40:21","TRT01SDTM":"2020-11-11 10:40:21","TRT01EDTM":"2022-11-11 22:40:21","TRT02SDTM":"2022-11-11 22:40:21","TRT02EDTM":"2023-11-12 04:40:21","AP01SDTM":"2020-11-11 10:40:21","AP01EDTM":"2022-11-11 22:40:21","AP02SDTM":"2022-11-11 22:40:21","AP02EDTM":"2023-11-12 04:40:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-12","EOSDY":1096,"LSTALVDT":"2023-12-04","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5558,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99471,"AVALU":"g/L","BASE2":2.87355,"BASE":2.82056,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12116,"PCHG2":4.21637,"CHG":0.17416,"PCHG":6.17454,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-27 10:40:21","ADY":1050,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-148","SUBJID":"id-148","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.39563,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-16","TRTSDTM":"2019-06-17 13:39:24","TRTEDTM":"2022-06-17 07:39:24","TRT01SDTM":"2019-06-17 13:39:24","TRT01EDTM":"2021-06-17 01:39:24","TRT02SDTM":"2021-06-17 01:39:24","TRT02EDTM":"2022-06-17 07:39:24","AP01SDTM":"2019-06-17 13:39:24","AP01EDTM":"2021-06-17 01:39:24","AP02SDTM":"2021-06-17 01:39:24","AP02EDTM":"2022-06-17 07:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-17","EOSDY":1096,"LSTALVDT":"2022-07-01","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1292,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":37.804,"AVALU":"U/L","BASE2":37.804,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-04 13:39:24","ADY":140,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-148","SUBJID":"id-148","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.39563,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-16","TRTSDTM":"2019-06-17 13:39:24","TRTEDTM":"2022-06-17 07:39:24","TRT01SDTM":"2019-06-17 13:39:24","TRT01EDTM":"2021-06-17 01:39:24","TRT02SDTM":"2021-06-17 01:39:24","TRT02EDTM":"2022-06-17 07:39:24","AP01SDTM":"2019-06-17 13:39:24","AP01EDTM":"2021-06-17 01:39:24","AP02SDTM":"2021-06-17 01:39:24","AP02EDTM":"2022-06-17 07:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-17","EOSDY":1096,"LSTALVDT":"2022-07-01","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":661,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.9687,"AVALU":"U/L","BASE2":37.804,"BASE":12.9687,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-24.8353,"PCHG2":-65.6949,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-24 13:39:24","ADY":221,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-148","SUBJID":"id-148","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.39563,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-16","TRTSDTM":"2019-06-17 13:39:24","TRTEDTM":"2022-06-17 07:39:24","TRT01SDTM":"2019-06-17 13:39:24","TRT01EDTM":"2021-06-17 01:39:24","TRT02SDTM":"2021-06-17 01:39:24","TRT02EDTM":"2022-06-17 07:39:24","AP01SDTM":"2019-06-17 13:39:24","AP01EDTM":"2021-06-17 01:39:24","AP02SDTM":"2021-06-17 01:39:24","AP02EDTM":"2022-06-17 07:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-17","EOSDY":1096,"LSTALVDT":"2022-07-01","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6549,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.29009,"AVALU":"U/L","BASE2":37.804,"BASE":12.9687,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-30.51391,"PCHG2":-80.71608,"CHG":-5.67861,"PCHG":-43.78703,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-21 13:39:24","ADY":431,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-148","SUBJID":"id-148","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.39563,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-16","TRTSDTM":"2019-06-17 13:39:24","TRTEDTM":"2022-06-17 07:39:24","TRT01SDTM":"2019-06-17 13:39:24","TRT01EDTM":"2021-06-17 01:39:24","TRT02SDTM":"2021-06-17 01:39:24","TRT02EDTM":"2022-06-17 07:39:24","AP01SDTM":"2019-06-17 13:39:24","AP01EDTM":"2021-06-17 01:39:24","AP02SDTM":"2021-06-17 01:39:24","AP02EDTM":"2022-06-17 07:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-17","EOSDY":1096,"LSTALVDT":"2022-07-01","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4298,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.07316,"AVALU":"U/L","BASE2":37.804,"BASE":12.9687,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-30.73084,"PCHG2":-81.28993,"CHG":-5.89554,"PCHG":-45.45979,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-11 13:39:24","ADY":605,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-148","SUBJID":"id-148","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.39563,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-16","TRTSDTM":"2019-06-17 13:39:24","TRTEDTM":"2022-06-17 07:39:24","TRT01SDTM":"2019-06-17 13:39:24","TRT01EDTM":"2021-06-17 01:39:24","TRT02SDTM":"2021-06-17 01:39:24","TRT02EDTM":"2022-06-17 07:39:24","AP01SDTM":"2019-06-17 13:39:24","AP01EDTM":"2021-06-17 01:39:24","AP02SDTM":"2021-06-17 01:39:24","AP02EDTM":"2022-06-17 07:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-17","EOSDY":1096,"LSTALVDT":"2022-07-01","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7341,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.4615,"AVALU":"U/L","BASE2":37.804,"BASE":12.9687,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.3425,"PCHG2":-45.87478,"CHG":7.4928,"PCHG":57.77601,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-02 13:39:24","ADY":869,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-148","SUBJID":"id-148","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.39563,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-16","TRTSDTM":"2019-06-17 13:39:24","TRTEDTM":"2022-06-17 07:39:24","TRT01SDTM":"2019-06-17 13:39:24","TRT01EDTM":"2021-06-17 01:39:24","TRT02SDTM":"2021-06-17 01:39:24","TRT02EDTM":"2022-06-17 07:39:24","AP01SDTM":"2019-06-17 13:39:24","AP01EDTM":"2021-06-17 01:39:24","AP02SDTM":"2021-06-17 01:39:24","AP02EDTM":"2022-06-17 07:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-17","EOSDY":1096,"LSTALVDT":"2022-07-01","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":568,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.62985,"AVALU":"U/L","BASE2":37.804,"BASE":12.9687,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-26.17415,"PCHG2":-69.23645,"CHG":-1.33885,"PCHG":-10.32368,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-06 13:39:24","ADY":873,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-148","SUBJID":"id-148","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.39563,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-16","TRTSDTM":"2019-06-17 13:39:24","TRTEDTM":"2022-06-17 07:39:24","TRT01SDTM":"2019-06-17 13:39:24","TRT01EDTM":"2021-06-17 01:39:24","TRT02SDTM":"2021-06-17 01:39:24","TRT02EDTM":"2022-06-17 07:39:24","AP01SDTM":"2019-06-17 13:39:24","AP01EDTM":"2021-06-17 01:39:24","AP02SDTM":"2021-06-17 01:39:24","AP02EDTM":"2022-06-17 07:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-17","EOSDY":1096,"LSTALVDT":"2022-07-01","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5662,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.11743,"AVALU":"U/L","BASE2":37.804,"BASE":12.9687,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-22.68657,"PCHG2":-60.01102,"CHG":2.14873,"PCHG":16.56862,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-05 13:39:24","ADY":902,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-148","SUBJID":"id-148","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.39563,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-16","TRTSDTM":"2019-06-17 13:39:24","TRTEDTM":"2022-06-17 07:39:24","TRT01SDTM":"2019-06-17 13:39:24","TRT01EDTM":"2021-06-17 01:39:24","TRT02SDTM":"2021-06-17 01:39:24","TRT02EDTM":"2022-06-17 07:39:24","AP01SDTM":"2019-06-17 13:39:24","AP01EDTM":"2021-06-17 01:39:24","AP02SDTM":"2021-06-17 01:39:24","AP02EDTM":"2022-06-17 07:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-17","EOSDY":1096,"LSTALVDT":"2022-07-01","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7086,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.06779,"AVALU":"mg/L","BASE2":9.06779,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-04 13:39:24","ADY":140,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-148","SUBJID":"id-148","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.39563,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-16","TRTSDTM":"2019-06-17 13:39:24","TRTEDTM":"2022-06-17 07:39:24","TRT01SDTM":"2019-06-17 13:39:24","TRT01EDTM":"2021-06-17 01:39:24","TRT02SDTM":"2021-06-17 01:39:24","TRT02EDTM":"2022-06-17 07:39:24","AP01SDTM":"2019-06-17 13:39:24","AP01EDTM":"2021-06-17 01:39:24","AP02SDTM":"2021-06-17 01:39:24","AP02EDTM":"2022-06-17 07:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-17","EOSDY":1096,"LSTALVDT":"2022-07-01","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1759,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.11632,"AVALU":"mg/L","BASE2":9.06779,"BASE":9.11632,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.04853,"PCHG2":0.53522,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-24 13:39:24","ADY":221,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-148","SUBJID":"id-148","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.39563,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-16","TRTSDTM":"2019-06-17 13:39:24","TRTEDTM":"2022-06-17 07:39:24","TRT01SDTM":"2019-06-17 13:39:24","TRT01EDTM":"2021-06-17 01:39:24","TRT02SDTM":"2021-06-17 01:39:24","TRT02EDTM":"2022-06-17 07:39:24","AP01SDTM":"2019-06-17 13:39:24","AP01EDTM":"2021-06-17 01:39:24","AP02SDTM":"2021-06-17 01:39:24","AP02EDTM":"2022-06-17 07:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-17","EOSDY":1096,"LSTALVDT":"2022-07-01","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":412,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.31729,"AVALU":"mg/L","BASE2":9.06779,"BASE":9.11632,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.7505,"PCHG2":-8.2765,"CHG":-0.79903,"PCHG":-8.76481,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-21 13:39:24","ADY":431,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-148","SUBJID":"id-148","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.39563,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-16","TRTSDTM":"2019-06-17 13:39:24","TRTEDTM":"2022-06-17 07:39:24","TRT01SDTM":"2019-06-17 13:39:24","TRT01EDTM":"2021-06-17 01:39:24","TRT02SDTM":"2021-06-17 01:39:24","TRT02EDTM":"2022-06-17 07:39:24","AP01SDTM":"2019-06-17 13:39:24","AP01EDTM":"2021-06-17 01:39:24","AP02SDTM":"2021-06-17 01:39:24","AP02EDTM":"2022-06-17 07:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-17","EOSDY":1096,"LSTALVDT":"2022-07-01","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6451,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.52713,"AVALU":"mg/L","BASE2":9.06779,"BASE":9.11632,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.54066,"PCHG2":-5.96242,"CHG":-0.58919,"PCHG":-6.46305,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-11 13:39:24","ADY":605,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-148","SUBJID":"id-148","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.39563,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-16","TRTSDTM":"2019-06-17 13:39:24","TRTEDTM":"2022-06-17 07:39:24","TRT01SDTM":"2019-06-17 13:39:24","TRT01EDTM":"2021-06-17 01:39:24","TRT02SDTM":"2021-06-17 01:39:24","TRT02EDTM":"2022-06-17 07:39:24","AP01SDTM":"2019-06-17 13:39:24","AP01EDTM":"2021-06-17 01:39:24","AP02SDTM":"2021-06-17 01:39:24","AP02EDTM":"2022-06-17 07:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-17","EOSDY":1096,"LSTALVDT":"2022-07-01","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5028,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.01306,"AVALU":"mg/L","BASE2":9.06779,"BASE":9.11632,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.94527,"PCHG2":10.42452,"CHG":0.89674,"PCHG":9.83665,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-11-02 13:39:24","ADY":869,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-148","SUBJID":"id-148","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.39563,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-16","TRTSDTM":"2019-06-17 13:39:24","TRTEDTM":"2022-06-17 07:39:24","TRT01SDTM":"2019-06-17 13:39:24","TRT01EDTM":"2021-06-17 01:39:24","TRT02SDTM":"2021-06-17 01:39:24","TRT02EDTM":"2022-06-17 07:39:24","AP01SDTM":"2019-06-17 13:39:24","AP01EDTM":"2021-06-17 01:39:24","AP02SDTM":"2021-06-17 01:39:24","AP02EDTM":"2022-06-17 07:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-17","EOSDY":1096,"LSTALVDT":"2022-07-01","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6511,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.48404,"AVALU":"mg/L","BASE2":9.06779,"BASE":9.11632,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.58375,"PCHG2":-17.46565,"CHG":-1.63228,"PCHG":-17.90505,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-11-06 13:39:24","ADY":873,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-148","SUBJID":"id-148","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.39563,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-16","TRTSDTM":"2019-06-17 13:39:24","TRTEDTM":"2022-06-17 07:39:24","TRT01SDTM":"2019-06-17 13:39:24","TRT01EDTM":"2021-06-17 01:39:24","TRT02SDTM":"2021-06-17 01:39:24","TRT02EDTM":"2022-06-17 07:39:24","AP01SDTM":"2019-06-17 13:39:24","AP01EDTM":"2021-06-17 01:39:24","AP02SDTM":"2021-06-17 01:39:24","AP02EDTM":"2022-06-17 07:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-17","EOSDY":1096,"LSTALVDT":"2022-07-01","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":591,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.52249,"AVALU":"mg/L","BASE2":9.06779,"BASE":9.11632,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.5453,"PCHG2":-6.01359,"CHG":-0.59383,"PCHG":-6.51394,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-05 13:39:24","ADY":902,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-148","SUBJID":"id-148","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.39563,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-16","TRTSDTM":"2019-06-17 13:39:24","TRTEDTM":"2022-06-17 07:39:24","TRT01SDTM":"2019-06-17 13:39:24","TRT01EDTM":"2021-06-17 01:39:24","TRT02SDTM":"2021-06-17 01:39:24","TRT02EDTM":"2022-06-17 07:39:24","AP01SDTM":"2019-06-17 13:39:24","AP01EDTM":"2021-06-17 01:39:24","AP02SDTM":"2021-06-17 01:39:24","AP02EDTM":"2022-06-17 07:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-17","EOSDY":1096,"LSTALVDT":"2022-07-01","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4796,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82663,"AVALU":"g/L","BASE2":2.82663,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-04 13:39:24","ADY":140,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-148","SUBJID":"id-148","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.39563,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-16","TRTSDTM":"2019-06-17 13:39:24","TRTEDTM":"2022-06-17 07:39:24","TRT01SDTM":"2019-06-17 13:39:24","TRT01EDTM":"2021-06-17 01:39:24","TRT02SDTM":"2021-06-17 01:39:24","TRT02EDTM":"2022-06-17 07:39:24","AP01SDTM":"2019-06-17 13:39:24","AP01EDTM":"2021-06-17 01:39:24","AP02SDTM":"2021-06-17 01:39:24","AP02EDTM":"2022-06-17 07:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-17","EOSDY":1096,"LSTALVDT":"2022-07-01","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4952,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87327,"AVALU":"g/L","BASE2":2.82663,"BASE":2.87327,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.04664,"PCHG2":1.64988,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-24 13:39:24","ADY":221,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-148","SUBJID":"id-148","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.39563,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-16","TRTSDTM":"2019-06-17 13:39:24","TRTEDTM":"2022-06-17 07:39:24","TRT01SDTM":"2019-06-17 13:39:24","TRT01EDTM":"2021-06-17 01:39:24","TRT02SDTM":"2021-06-17 01:39:24","TRT02EDTM":"2022-06-17 07:39:24","AP01SDTM":"2019-06-17 13:39:24","AP01EDTM":"2021-06-17 01:39:24","AP02SDTM":"2021-06-17 01:39:24","AP02EDTM":"2022-06-17 07:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-17","EOSDY":1096,"LSTALVDT":"2022-07-01","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7948,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86434,"AVALU":"g/L","BASE2":2.82663,"BASE":2.87327,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03771,"PCHG2":1.33396,"CHG":-0.00893,"PCHG":-0.3108,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-21 13:39:24","ADY":431,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-148","SUBJID":"id-148","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.39563,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-16","TRTSDTM":"2019-06-17 13:39:24","TRTEDTM":"2022-06-17 07:39:24","TRT01SDTM":"2019-06-17 13:39:24","TRT01EDTM":"2021-06-17 01:39:24","TRT02SDTM":"2021-06-17 01:39:24","TRT02EDTM":"2022-06-17 07:39:24","AP01SDTM":"2019-06-17 13:39:24","AP01EDTM":"2021-06-17 01:39:24","AP02SDTM":"2021-06-17 01:39:24","AP02EDTM":"2022-06-17 07:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-17","EOSDY":1096,"LSTALVDT":"2022-07-01","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":701,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91526,"AVALU":"g/L","BASE2":2.82663,"BASE":2.87327,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08863,"PCHG2":3.13547,"CHG":0.04199,"PCHG":1.46147,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-11 13:39:24","ADY":605,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-148","SUBJID":"id-148","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.39563,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-16","TRTSDTM":"2019-06-17 13:39:24","TRTEDTM":"2022-06-17 07:39:24","TRT01SDTM":"2019-06-17 13:39:24","TRT01EDTM":"2021-06-17 01:39:24","TRT02SDTM":"2021-06-17 01:39:24","TRT02EDTM":"2022-06-17 07:39:24","AP01SDTM":"2019-06-17 13:39:24","AP01EDTM":"2021-06-17 01:39:24","AP02SDTM":"2021-06-17 01:39:24","AP02EDTM":"2022-06-17 07:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-17","EOSDY":1096,"LSTALVDT":"2022-07-01","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6793,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96341,"AVALU":"g/L","BASE2":2.82663,"BASE":2.87327,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13678,"PCHG2":4.83887,"CHG":0.09014,"PCHG":3.13723,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-02 13:39:24","ADY":869,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-148","SUBJID":"id-148","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.39563,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-16","TRTSDTM":"2019-06-17 13:39:24","TRTEDTM":"2022-06-17 07:39:24","TRT01SDTM":"2019-06-17 13:39:24","TRT01EDTM":"2021-06-17 01:39:24","TRT02SDTM":"2021-06-17 01:39:24","TRT02EDTM":"2022-06-17 07:39:24","AP01SDTM":"2019-06-17 13:39:24","AP01EDTM":"2021-06-17 01:39:24","AP02SDTM":"2021-06-17 01:39:24","AP02EDTM":"2022-06-17 07:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-17","EOSDY":1096,"LSTALVDT":"2022-07-01","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1055,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9191,"AVALU":"g/L","BASE2":2.82663,"BASE":2.87327,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09247,"PCHG2":3.2713,"CHG":0.04583,"PCHG":1.5951,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-06 13:39:24","ADY":873,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-148","SUBJID":"id-148","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.39563,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-06-16","TRTSDTM":"2019-06-17 13:39:24","TRTEDTM":"2022-06-17 07:39:24","TRT01SDTM":"2019-06-17 13:39:24","TRT01EDTM":"2021-06-17 01:39:24","TRT02SDTM":"2021-06-17 01:39:24","TRT02EDTM":"2022-06-17 07:39:24","AP01SDTM":"2019-06-17 13:39:24","AP01EDTM":"2021-06-17 01:39:24","AP02SDTM":"2021-06-17 01:39:24","AP02EDTM":"2022-06-17 07:39:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-17","EOSDY":1096,"LSTALVDT":"2022-07-01","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3969,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94902,"AVALU":"g/L","BASE2":2.82663,"BASE":2.87327,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12239,"PCHG2":4.32981,"CHG":0.07575,"PCHG":2.63642,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-05 13:39:24","ADY":902,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-169","SUBJID":"id-169","SITEID":"PAK-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.87444,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-12","TRTSDTM":"2019-11-15 13:39:58","TRT01SDTM":"2019-11-15 13:39:58","AP01SDTM":"2019-11-15 13:39:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4534,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.43103,"AVALU":"U/L","BASE2":17.43103,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-30 13:39:58","ADY":76,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-169","SUBJID":"id-169","SITEID":"PAK-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.87444,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-12","TRTSDTM":"2019-11-15 13:39:58","TRT01SDTM":"2019-11-15 13:39:58","AP01SDTM":"2019-11-15 13:39:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2602,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.61772,"AVALU":"U/L","BASE2":17.43103,"BASE":17.61772,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.18669,"PCHG2":1.07102,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-30 13:39:58","ADY":167,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-169","SUBJID":"id-169","SITEID":"PAK-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.87444,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-12","TRTSDTM":"2019-11-15 13:39:58","TRT01SDTM":"2019-11-15 13:39:58","AP01SDTM":"2019-11-15 13:39:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6375,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.36258,"AVALU":"U/L","BASE2":17.43103,"BASE":17.61772,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.93155,"PCHG2":34.02867,"CHG":5.74486,"PCHG":32.6084,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-14 13:39:58","ADY":242,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-169","SUBJID":"id-169","SITEID":"PAK-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.87444,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-12","TRTSDTM":"2019-11-15 13:39:58","TRT01SDTM":"2019-11-15 13:39:58","AP01SDTM":"2019-11-15 13:39:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5175,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.82003,"AVALU":"U/L","BASE2":17.43103,"BASE":17.61772,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.61101,"PCHG2":-55.13734,"CHG":-9.7977,"PCHG":-55.61273,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-10 13:39:58","ADY":269,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-169","SUBJID":"id-169","SITEID":"PAK-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.87444,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-12","TRTSDTM":"2019-11-15 13:39:58","TRT01SDTM":"2019-11-15 13:39:58","AP01SDTM":"2019-11-15 13:39:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":832,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.65977,"AVALU":"U/L","BASE2":17.43103,"BASE":17.61772,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.77126,"PCHG2":-4.42465,"CHG":-0.95795,"PCHG":-5.43743,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-15 13:39:58","ADY":547,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-169","SUBJID":"id-169","SITEID":"PAK-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.87444,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-12","TRTSDTM":"2019-11-15 13:39:58","TRT01SDTM":"2019-11-15 13:39:58","AP01SDTM":"2019-11-15 13:39:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5675,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.6265,"AVALU":"U/L","BASE2":17.43103,"BASE":17.61772,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.80453,"PCHG2":-96.40584,"CHG":-16.99122,"PCHG":-96.44393,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-07-12 13:39:58","ADY":605,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-169","SUBJID":"id-169","SITEID":"PAK-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.87444,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-12","TRTSDTM":"2019-11-15 13:39:58","TRT01SDTM":"2019-11-15 13:39:58","AP01SDTM":"2019-11-15 13:39:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6243,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.11232,"AVALU":"U/L","BASE2":17.43103,"BASE":17.61772,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.31871,"PCHG2":-99.35563,"CHG":-17.5054,"PCHG":-99.36246,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-11-06 13:39:58","ADY":722,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-169","SUBJID":"id-169","SITEID":"PAK-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.87444,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-12","TRTSDTM":"2019-11-15 13:39:58","TRT01SDTM":"2019-11-15 13:39:58","AP01SDTM":"2019-11-15 13:39:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6868,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.0412,"AVALU":"mg/L","BASE2":11.0412,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-01-30 13:39:58","ADY":76,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-169","SUBJID":"id-169","SITEID":"PAK-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.87444,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-12","TRTSDTM":"2019-11-15 13:39:58","TRT01SDTM":"2019-11-15 13:39:58","AP01SDTM":"2019-11-15 13:39:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1237,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.3503,"AVALU":"mg/L","BASE2":11.0412,"BASE":9.3503,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.69089,"PCHG2":-15.3144,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-30 13:39:58","ADY":167,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-169","SUBJID":"id-169","SITEID":"PAK-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.87444,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-12","TRTSDTM":"2019-11-15 13:39:58","TRT01SDTM":"2019-11-15 13:39:58","AP01SDTM":"2019-11-15 13:39:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1981,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.18392,"AVALU":"mg/L","BASE2":11.0412,"BASE":9.3503,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.85727,"PCHG2":-25.87828,"CHG":-1.16638,"PCHG":-12.47424,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-14 13:39:58","ADY":242,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-169","SUBJID":"id-169","SITEID":"PAK-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.87444,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-12","TRTSDTM":"2019-11-15 13:39:58","TRT01SDTM":"2019-11-15 13:39:58","AP01SDTM":"2019-11-15 13:39:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3149,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.72134,"AVALU":"mg/L","BASE2":11.0412,"BASE":9.3503,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.31986,"PCHG2":-39.12491,"CHG":-2.62897,"PCHG":-28.11637,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-08-10 13:39:58","ADY":269,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-169","SUBJID":"id-169","SITEID":"PAK-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.87444,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-12","TRTSDTM":"2019-11-15 13:39:58","TRT01SDTM":"2019-11-15 13:39:58","AP01SDTM":"2019-11-15 13:39:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5174,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.58355,"AVALU":"mg/L","BASE2":11.0412,"BASE":9.3503,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.45765,"PCHG2":-22.25891,"CHG":-0.76676,"PCHG":-8.20034,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-15 13:39:58","ADY":547,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-169","SUBJID":"id-169","SITEID":"PAK-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.87444,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-12","TRTSDTM":"2019-11-15 13:39:58","TRT01SDTM":"2019-11-15 13:39:58","AP01SDTM":"2019-11-15 13:39:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4779,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.29903,"AVALU":"mg/L","BASE2":11.0412,"BASE":9.3503,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.74216,"PCHG2":-15.77876,"CHG":-0.05127,"PCHG":-0.54833,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-12 13:39:58","ADY":605,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-169","SUBJID":"id-169","SITEID":"PAK-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.87444,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-12","TRTSDTM":"2019-11-15 13:39:58","TRT01SDTM":"2019-11-15 13:39:58","AP01SDTM":"2019-11-15 13:39:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":929,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.2546,"AVALU":"mg/L","BASE2":11.0412,"BASE":9.3503,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.7866,"PCHG2":-7.12422,"CHG":0.90429,"PCHG":9.67128,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-11-06 13:39:58","ADY":722,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-169","SUBJID":"id-169","SITEID":"PAK-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.87444,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-12","TRTSDTM":"2019-11-15 13:39:58","TRT01SDTM":"2019-11-15 13:39:58","AP01SDTM":"2019-11-15 13:39:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1120,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9206,"AVALU":"g/L","BASE2":2.9206,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-30 13:39:58","ADY":76,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-169","SUBJID":"id-169","SITEID":"PAK-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.87444,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-12","TRTSDTM":"2019-11-15 13:39:58","TRT01SDTM":"2019-11-15 13:39:58","AP01SDTM":"2019-11-15 13:39:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1624,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91609,"AVALU":"g/L","BASE2":2.9206,"BASE":2.91609,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.00451,"PCHG2":-0.1543,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-30 13:39:58","ADY":167,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-169","SUBJID":"id-169","SITEID":"PAK-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.87444,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-12","TRTSDTM":"2019-11-15 13:39:58","TRT01SDTM":"2019-11-15 13:39:58","AP01SDTM":"2019-11-15 13:39:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":729,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75835,"AVALU":"g/L","BASE2":2.9206,"BASE":2.91609,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16225,"PCHG2":-5.55528,"CHG":-0.15774,"PCHG":-5.40933,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-14 13:39:58","ADY":242,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-169","SUBJID":"id-169","SITEID":"PAK-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.87444,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-12","TRTSDTM":"2019-11-15 13:39:58","TRT01SDTM":"2019-11-15 13:39:58","AP01SDTM":"2019-11-15 13:39:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1425,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83701,"AVALU":"g/L","BASE2":2.9206,"BASE":2.91609,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08358,"PCHG2":-2.86187,"CHG":-0.07908,"PCHG":-2.71176,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-10 13:39:58","ADY":269,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-169","SUBJID":"id-169","SITEID":"PAK-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.87444,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-12","TRTSDTM":"2019-11-15 13:39:58","TRT01SDTM":"2019-11-15 13:39:58","AP01SDTM":"2019-11-15 13:39:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":234,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93282,"AVALU":"g/L","BASE2":2.9206,"BASE":2.91609,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01222,"PCHG2":0.41856,"CHG":0.01673,"PCHG":0.57374,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-15 13:39:58","ADY":547,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-169","SUBJID":"id-169","SITEID":"PAK-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.87444,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-12","TRTSDTM":"2019-11-15 13:39:58","TRT01SDTM":"2019-11-15 13:39:58","AP01SDTM":"2019-11-15 13:39:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6707,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89415,"AVALU":"g/L","BASE2":2.9206,"BASE":2.91609,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02644,"PCHG2":-0.90543,"CHG":-0.02194,"PCHG":-0.75229,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-12 13:39:58","ADY":605,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-169","SUBJID":"id-169","SITEID":"PAK-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.87444,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-12","TRTSDTM":"2019-11-15 13:39:58","TRT01SDTM":"2019-11-15 13:39:58","AP01SDTM":"2019-11-15 13:39:58","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1543,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79036,"AVALU":"g/L","BASE2":2.9206,"BASE":2.91609,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13024,"PCHG2":-4.45925,"CHG":-0.12573,"PCHG":-4.31161,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-06 13:39:58","ADY":722,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-17","SUBJID":"id-17","SITEID":"PAK-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.27195,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-08","TRTSDTM":"2019-07-12 01:03:24","TRTEDTM":"2022-07-11 19:03:24","TRT01SDTM":"2019-07-12 01:03:24","TRT01EDTM":"2021-07-11 13:03:24","TRT02SDTM":"2021-07-11 13:03:24","TRT02EDTM":"2022-07-11 19:03:24","AP01SDTM":"2019-07-12 01:03:24","AP01EDTM":"2021-07-11 13:03:24","AP02SDTM":"2021-07-11 13:03:24","AP02EDTM":"2022-07-11 19:03:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-11","EOSDY":1096,"LSTALVDT":"2022-07-30","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6993,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.89739,"AVALU":"U/L","BASE2":24.89739,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-31 01:03:24","ADY":50,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-17","SUBJID":"id-17","SITEID":"PAK-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.27195,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-08","TRTSDTM":"2019-07-12 01:03:24","TRTEDTM":"2022-07-11 19:03:24","TRT01SDTM":"2019-07-12 01:03:24","TRT01EDTM":"2021-07-11 13:03:24","TRT02SDTM":"2021-07-11 13:03:24","TRT02EDTM":"2022-07-11 19:03:24","AP01SDTM":"2019-07-12 01:03:24","AP01EDTM":"2021-07-11 13:03:24","AP02SDTM":"2021-07-11 13:03:24","AP02EDTM":"2022-07-11 19:03:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-11","EOSDY":1096,"LSTALVDT":"2022-07-30","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":312,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.71442,"AVALU":"U/L","BASE2":24.89739,"BASE":8.71442,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-16.18297,"PCHG2":-64.99866,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-09 01:03:24","ADY":241,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-17","SUBJID":"id-17","SITEID":"PAK-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.27195,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-08","TRTSDTM":"2019-07-12 01:03:24","TRTEDTM":"2022-07-11 19:03:24","TRT01SDTM":"2019-07-12 01:03:24","TRT01EDTM":"2021-07-11 13:03:24","TRT02SDTM":"2021-07-11 13:03:24","TRT02EDTM":"2022-07-11 19:03:24","AP01SDTM":"2019-07-12 01:03:24","AP01EDTM":"2021-07-11 13:03:24","AP02SDTM":"2021-07-11 13:03:24","AP02EDTM":"2022-07-11 19:03:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-11","EOSDY":1096,"LSTALVDT":"2022-07-30","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1270,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.14771,"AVALU":"U/L","BASE2":24.89739,"BASE":8.71442,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.25032,"PCHG2":5.02187,"CHG":17.43329,"PCHG":200.05102,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-24 01:03:24","ADY":835,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-17","SUBJID":"id-17","SITEID":"PAK-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.27195,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-08","TRTSDTM":"2019-07-12 01:03:24","TRTEDTM":"2022-07-11 19:03:24","TRT01SDTM":"2019-07-12 01:03:24","TRT01EDTM":"2021-07-11 13:03:24","TRT02SDTM":"2021-07-11 13:03:24","TRT02EDTM":"2022-07-11 19:03:24","AP01SDTM":"2019-07-12 01:03:24","AP01EDTM":"2021-07-11 13:03:24","AP02SDTM":"2021-07-11 13:03:24","AP02EDTM":"2022-07-11 19:03:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-11","EOSDY":1096,"LSTALVDT":"2022-07-30","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3242,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.66787,"AVALU":"U/L","BASE2":24.89739,"BASE":8.71442,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.22952,"PCHG2":-29.03728,"CHG":8.95345,"PCHG":102.74289,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-23 01:03:24","ADY":895,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-17","SUBJID":"id-17","SITEID":"PAK-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.27195,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-08","TRTSDTM":"2019-07-12 01:03:24","TRTEDTM":"2022-07-11 19:03:24","TRT01SDTM":"2019-07-12 01:03:24","TRT01EDTM":"2021-07-11 13:03:24","TRT02SDTM":"2021-07-11 13:03:24","TRT02EDTM":"2022-07-11 19:03:24","AP01SDTM":"2019-07-12 01:03:24","AP01EDTM":"2021-07-11 13:03:24","AP02SDTM":"2021-07-11 13:03:24","AP02EDTM":"2022-07-11 19:03:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-11","EOSDY":1096,"LSTALVDT":"2022-07-30","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1975,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.3057,"AVALU":"U/L","BASE2":24.89739,"BASE":8.71442,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.59169,"PCHG2":-66.64027,"CHG":-0.40872,"PCHG":-4.69013,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-17 01:03:24","ADY":951,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-17","SUBJID":"id-17","SITEID":"PAK-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.27195,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-08","TRTSDTM":"2019-07-12 01:03:24","TRTEDTM":"2022-07-11 19:03:24","TRT01SDTM":"2019-07-12 01:03:24","TRT01EDTM":"2021-07-11 13:03:24","TRT02SDTM":"2021-07-11 13:03:24","TRT02EDTM":"2022-07-11 19:03:24","AP01SDTM":"2019-07-12 01:03:24","AP01EDTM":"2021-07-11 13:03:24","AP02SDTM":"2021-07-11 13:03:24","AP02EDTM":"2022-07-11 19:03:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-11","EOSDY":1096,"LSTALVDT":"2022-07-30","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2914,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.77728,"AVALU":"U/L","BASE2":24.89739,"BASE":8.71442,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.12012,"PCHG2":-16.54838,"CHG":12.06286,"PCHG":138.42408,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-13 01:03:24","ADY":1006,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-17","SUBJID":"id-17","SITEID":"PAK-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.27195,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-08","TRTSDTM":"2019-07-12 01:03:24","TRTEDTM":"2022-07-11 19:03:24","TRT01SDTM":"2019-07-12 01:03:24","TRT01EDTM":"2021-07-11 13:03:24","TRT02SDTM":"2021-07-11 13:03:24","TRT02EDTM":"2022-07-11 19:03:24","AP01SDTM":"2019-07-12 01:03:24","AP01EDTM":"2021-07-11 13:03:24","AP02SDTM":"2021-07-11 13:03:24","AP02EDTM":"2022-07-11 19:03:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-11","EOSDY":1096,"LSTALVDT":"2022-07-30","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":43,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.85288,"AVALU":"U/L","BASE2":24.89739,"BASE":8.71442,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.04451,"PCHG2":-44.36012,"CHG":5.13846,"PCHG":58.96502,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-13 01:03:24","ADY":1036,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-17","SUBJID":"id-17","SITEID":"PAK-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.27195,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-08","TRTSDTM":"2019-07-12 01:03:24","TRTEDTM":"2022-07-11 19:03:24","TRT01SDTM":"2019-07-12 01:03:24","TRT01EDTM":"2021-07-11 13:03:24","TRT02SDTM":"2021-07-11 13:03:24","TRT02EDTM":"2022-07-11 19:03:24","AP01SDTM":"2019-07-12 01:03:24","AP01EDTM":"2021-07-11 13:03:24","AP02SDTM":"2021-07-11 13:03:24","AP02EDTM":"2022-07-11 19:03:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-11","EOSDY":1096,"LSTALVDT":"2022-07-30","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3236,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.27813,"AVALU":"mg/L","BASE2":9.27813,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-31 01:03:24","ADY":50,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-17","SUBJID":"id-17","SITEID":"PAK-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.27195,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-08","TRTSDTM":"2019-07-12 01:03:24","TRTEDTM":"2022-07-11 19:03:24","TRT01SDTM":"2019-07-12 01:03:24","TRT01EDTM":"2021-07-11 13:03:24","TRT02SDTM":"2021-07-11 13:03:24","TRT02EDTM":"2022-07-11 19:03:24","AP01SDTM":"2019-07-12 01:03:24","AP01EDTM":"2021-07-11 13:03:24","AP02SDTM":"2021-07-11 13:03:24","AP02EDTM":"2022-07-11 19:03:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-11","EOSDY":1096,"LSTALVDT":"2022-07-30","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4886,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.64635,"AVALU":"mg/L","BASE2":9.27813,"BASE":8.64635,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.63178,"PCHG2":-6.80931,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-09 01:03:24","ADY":241,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-17","SUBJID":"id-17","SITEID":"PAK-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.27195,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-08","TRTSDTM":"2019-07-12 01:03:24","TRTEDTM":"2022-07-11 19:03:24","TRT01SDTM":"2019-07-12 01:03:24","TRT01EDTM":"2021-07-11 13:03:24","TRT02SDTM":"2021-07-11 13:03:24","TRT02EDTM":"2022-07-11 19:03:24","AP01SDTM":"2019-07-12 01:03:24","AP01EDTM":"2021-07-11 13:03:24","AP02SDTM":"2021-07-11 13:03:24","AP02EDTM":"2022-07-11 19:03:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-11","EOSDY":1096,"LSTALVDT":"2022-07-30","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1267,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.60166,"AVALU":"mg/L","BASE2":9.27813,"BASE":8.64635,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.67647,"PCHG2":-7.29106,"CHG":-0.0447,"PCHG":-0.51694,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-24 01:03:24","ADY":835,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-17","SUBJID":"id-17","SITEID":"PAK-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.27195,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-08","TRTSDTM":"2019-07-12 01:03:24","TRTEDTM":"2022-07-11 19:03:24","TRT01SDTM":"2019-07-12 01:03:24","TRT01EDTM":"2021-07-11 13:03:24","TRT02SDTM":"2021-07-11 13:03:24","TRT02EDTM":"2022-07-11 19:03:24","AP01SDTM":"2019-07-12 01:03:24","AP01EDTM":"2021-07-11 13:03:24","AP02SDTM":"2021-07-11 13:03:24","AP02EDTM":"2022-07-11 19:03:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-11","EOSDY":1096,"LSTALVDT":"2022-07-30","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3703,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.56986,"AVALU":"mg/L","BASE2":9.27813,"BASE":8.64635,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.29172,"PCHG2":3.14422,"CHG":0.9235,"PCHG":10.68082,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-23 01:03:24","ADY":895,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-17","SUBJID":"id-17","SITEID":"PAK-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.27195,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-08","TRTSDTM":"2019-07-12 01:03:24","TRTEDTM":"2022-07-11 19:03:24","TRT01SDTM":"2019-07-12 01:03:24","TRT01EDTM":"2021-07-11 13:03:24","TRT02SDTM":"2021-07-11 13:03:24","TRT02EDTM":"2022-07-11 19:03:24","AP01SDTM":"2019-07-12 01:03:24","AP01EDTM":"2021-07-11 13:03:24","AP02SDTM":"2021-07-11 13:03:24","AP02EDTM":"2022-07-11 19:03:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-11","EOSDY":1096,"LSTALVDT":"2022-07-30","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8052,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.81194,"AVALU":"mg/L","BASE2":9.27813,"BASE":8.64635,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.46619,"PCHG2":-5.02458,"CHG":0.16559,"PCHG":1.91514,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-17 01:03:24","ADY":951,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-17","SUBJID":"id-17","SITEID":"PAK-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.27195,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-08","TRTSDTM":"2019-07-12 01:03:24","TRTEDTM":"2022-07-11 19:03:24","TRT01SDTM":"2019-07-12 01:03:24","TRT01EDTM":"2021-07-11 13:03:24","TRT02SDTM":"2021-07-11 13:03:24","TRT02EDTM":"2022-07-11 19:03:24","AP01SDTM":"2019-07-12 01:03:24","AP01EDTM":"2021-07-11 13:03:24","AP02SDTM":"2021-07-11 13:03:24","AP02EDTM":"2022-07-11 19:03:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-11","EOSDY":1096,"LSTALVDT":"2022-07-30","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7365,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.80035,"AVALU":"mg/L","BASE2":9.27813,"BASE":8.64635,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.52222,"PCHG2":5.62854,"CHG":1.154,"PCHG":13.34666,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-13 01:03:24","ADY":1006,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-17","SUBJID":"id-17","SITEID":"PAK-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.27195,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-08","TRTSDTM":"2019-07-12 01:03:24","TRTEDTM":"2022-07-11 19:03:24","TRT01SDTM":"2019-07-12 01:03:24","TRT01EDTM":"2021-07-11 13:03:24","TRT02SDTM":"2021-07-11 13:03:24","TRT02EDTM":"2022-07-11 19:03:24","AP01SDTM":"2019-07-12 01:03:24","AP01EDTM":"2021-07-11 13:03:24","AP02SDTM":"2021-07-11 13:03:24","AP02EDTM":"2022-07-11 19:03:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-11","EOSDY":1096,"LSTALVDT":"2022-07-30","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":262,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.32357,"AVALU":"mg/L","BASE2":9.27813,"BASE":8.64635,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.95456,"PCHG2":-21.06636,"CHG":-1.32279,"PCHG":-15.29879,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2022-05-13 01:03:24","ADY":1036,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-17","SUBJID":"id-17","SITEID":"PAK-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.27195,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-08","TRTSDTM":"2019-07-12 01:03:24","TRTEDTM":"2022-07-11 19:03:24","TRT01SDTM":"2019-07-12 01:03:24","TRT01EDTM":"2021-07-11 13:03:24","TRT02SDTM":"2021-07-11 13:03:24","TRT02EDTM":"2022-07-11 19:03:24","AP01SDTM":"2019-07-12 01:03:24","AP01EDTM":"2021-07-11 13:03:24","AP02SDTM":"2021-07-11 13:03:24","AP02EDTM":"2022-07-11 19:03:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-11","EOSDY":1096,"LSTALVDT":"2022-07-30","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":220,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87834,"AVALU":"g/L","BASE2":2.87834,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-31 01:03:24","ADY":50,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-17","SUBJID":"id-17","SITEID":"PAK-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.27195,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-08","TRTSDTM":"2019-07-12 01:03:24","TRTEDTM":"2022-07-11 19:03:24","TRT01SDTM":"2019-07-12 01:03:24","TRT01EDTM":"2021-07-11 13:03:24","TRT02SDTM":"2021-07-11 13:03:24","TRT02EDTM":"2022-07-11 19:03:24","AP01SDTM":"2019-07-12 01:03:24","AP01EDTM":"2021-07-11 13:03:24","AP02SDTM":"2021-07-11 13:03:24","AP02EDTM":"2022-07-11 19:03:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-11","EOSDY":1096,"LSTALVDT":"2022-07-30","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1053,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90156,"AVALU":"g/L","BASE2":2.87834,"BASE":2.90156,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.02322,"PCHG2":0.80667,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-09 01:03:24","ADY":241,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-17","SUBJID":"id-17","SITEID":"PAK-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.27195,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-08","TRTSDTM":"2019-07-12 01:03:24","TRTEDTM":"2022-07-11 19:03:24","TRT01SDTM":"2019-07-12 01:03:24","TRT01EDTM":"2021-07-11 13:03:24","TRT02SDTM":"2021-07-11 13:03:24","TRT02EDTM":"2022-07-11 19:03:24","AP01SDTM":"2019-07-12 01:03:24","AP01EDTM":"2021-07-11 13:03:24","AP02SDTM":"2021-07-11 13:03:24","AP02EDTM":"2022-07-11 19:03:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-11","EOSDY":1096,"LSTALVDT":"2022-07-30","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4772,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94593,"AVALU":"g/L","BASE2":2.87834,"BASE":2.90156,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06759,"PCHG2":2.34814,"CHG":0.04437,"PCHG":1.52914,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-24 01:03:24","ADY":835,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-17","SUBJID":"id-17","SITEID":"PAK-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.27195,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-08","TRTSDTM":"2019-07-12 01:03:24","TRTEDTM":"2022-07-11 19:03:24","TRT01SDTM":"2019-07-12 01:03:24","TRT01EDTM":"2021-07-11 13:03:24","TRT02SDTM":"2021-07-11 13:03:24","TRT02EDTM":"2022-07-11 19:03:24","AP01SDTM":"2019-07-12 01:03:24","AP01EDTM":"2021-07-11 13:03:24","AP02SDTM":"2021-07-11 13:03:24","AP02EDTM":"2022-07-11 19:03:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-11","EOSDY":1096,"LSTALVDT":"2022-07-30","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1469,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9115,"AVALU":"g/L","BASE2":2.87834,"BASE":2.90156,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03317,"PCHG2":1.15225,"CHG":0.00995,"PCHG":0.34282,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-23 01:03:24","ADY":895,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-17","SUBJID":"id-17","SITEID":"PAK-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.27195,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-08","TRTSDTM":"2019-07-12 01:03:24","TRTEDTM":"2022-07-11 19:03:24","TRT01SDTM":"2019-07-12 01:03:24","TRT01EDTM":"2021-07-11 13:03:24","TRT02SDTM":"2021-07-11 13:03:24","TRT02EDTM":"2022-07-11 19:03:24","AP01SDTM":"2019-07-12 01:03:24","AP01EDTM":"2021-07-11 13:03:24","AP02SDTM":"2021-07-11 13:03:24","AP02EDTM":"2022-07-11 19:03:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-11","EOSDY":1096,"LSTALVDT":"2022-07-30","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4445,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.06409,"AVALU":"g/L","BASE2":2.87834,"BASE":2.90156,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18576,"PCHG2":6.45356,"CHG":0.16254,"PCHG":5.60171,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-02-17 01:03:24","ADY":951,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-17","SUBJID":"id-17","SITEID":"PAK-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.27195,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-08","TRTSDTM":"2019-07-12 01:03:24","TRTEDTM":"2022-07-11 19:03:24","TRT01SDTM":"2019-07-12 01:03:24","TRT01EDTM":"2021-07-11 13:03:24","TRT02SDTM":"2021-07-11 13:03:24","TRT02EDTM":"2022-07-11 19:03:24","AP01SDTM":"2019-07-12 01:03:24","AP01EDTM":"2021-07-11 13:03:24","AP02SDTM":"2021-07-11 13:03:24","AP02EDTM":"2022-07-11 19:03:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-11","EOSDY":1096,"LSTALVDT":"2022-07-30","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1250,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95372,"AVALU":"g/L","BASE2":2.87834,"BASE":2.90156,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07538,"PCHG2":2.61881,"CHG":0.05216,"PCHG":1.79764,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-13 01:03:24","ADY":1006,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-17","SUBJID":"id-17","SITEID":"PAK-1","AGE":33,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":9.27195,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-08","TRTSDTM":"2019-07-12 01:03:24","TRTEDTM":"2022-07-11 19:03:24","TRT01SDTM":"2019-07-12 01:03:24","TRT01EDTM":"2021-07-11 13:03:24","TRT02SDTM":"2021-07-11 13:03:24","TRT02EDTM":"2022-07-11 19:03:24","AP01SDTM":"2019-07-12 01:03:24","AP01EDTM":"2021-07-11 13:03:24","AP02SDTM":"2021-07-11 13:03:24","AP02EDTM":"2022-07-11 19:03:24","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-11","EOSDY":1096,"LSTALVDT":"2022-07-30","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7172,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93108,"AVALU":"g/L","BASE2":2.87834,"BASE":2.90156,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05274,"PCHG2":1.83229,"CHG":0.02952,"PCHG":1.01742,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-13 01:03:24","ADY":1036,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-178","SUBJID":"id-178","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.32131,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-06","TRTSDTM":"2019-06-06 02:47:09","TRTEDTM":"2022-02-20 02:00:41","TRT01SDTM":"2019-06-06 02:47:09","TRT01EDTM":"2021-02-19 20:00:41","TRT02SDTM":"2021-02-19 20:00:41","TRT02EDTM":"2022-02-20 02:00:41","AP01SDTM":"2019-06-06 02:47:09","AP01EDTM":"2021-02-19 20:00:41","AP02SDTM":"2021-02-19 20:00:41","AP02EDTM":"2022-02-20 02:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":990,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1027,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3822,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.87974,"AVALU":"U/L","BASE2":11.87974,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-30 02:47:09","ADY":85,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-178","SUBJID":"id-178","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.32131,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-06","TRTSDTM":"2019-06-06 02:47:09","TRTEDTM":"2022-02-20 02:00:41","TRT01SDTM":"2019-06-06 02:47:09","TRT01EDTM":"2021-02-19 20:00:41","TRT02SDTM":"2021-02-19 20:00:41","TRT02EDTM":"2022-02-20 02:00:41","AP01SDTM":"2019-06-06 02:47:09","AP01EDTM":"2021-02-19 20:00:41","AP02SDTM":"2021-02-19 20:00:41","AP02EDTM":"2022-02-20 02:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":990,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1027,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4985,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.35326,"AVALU":"U/L","BASE2":11.87974,"BASE":28.35326,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":16.47353,"PCHG2":138.66914,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-28 02:47:09","ADY":144,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-178","SUBJID":"id-178","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.32131,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-06","TRTSDTM":"2019-06-06 02:47:09","TRTEDTM":"2022-02-20 02:00:41","TRT01SDTM":"2019-06-06 02:47:09","TRT01EDTM":"2021-02-19 20:00:41","TRT02SDTM":"2021-02-19 20:00:41","TRT02EDTM":"2022-02-20 02:00:41","AP01SDTM":"2019-06-06 02:47:09","AP01EDTM":"2021-02-19 20:00:41","AP02SDTM":"2021-02-19 20:00:41","AP02EDTM":"2022-02-20 02:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":990,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1027,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7609,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.73607,"AVALU":"U/L","BASE2":11.87974,"BASE":28.35326,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.85634,"PCHG2":167.14459,"CHG":3.38281,"PCHG":11.93093,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-10 02:47:09","ADY":431,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-178","SUBJID":"id-178","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.32131,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-06","TRTSDTM":"2019-06-06 02:47:09","TRTEDTM":"2022-02-20 02:00:41","TRT01SDTM":"2019-06-06 02:47:09","TRT01EDTM":"2021-02-19 20:00:41","TRT02SDTM":"2021-02-19 20:00:41","TRT02EDTM":"2022-02-20 02:00:41","AP01SDTM":"2019-06-06 02:47:09","AP01EDTM":"2021-02-19 20:00:41","AP02SDTM":"2021-02-19 20:00:41","AP02EDTM":"2022-02-20 02:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":990,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1027,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":516,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.82873,"AVALU":"U/L","BASE2":11.87974,"BASE":28.35326,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.949,"PCHG2":58.49453,"CHG":-9.52453,"PCHG":-33.59237,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-21 02:47:09","ADY":473,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-178","SUBJID":"id-178","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.32131,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-06","TRTSDTM":"2019-06-06 02:47:09","TRTEDTM":"2022-02-20 02:00:41","TRT01SDTM":"2019-06-06 02:47:09","TRT01EDTM":"2021-02-19 20:00:41","TRT02SDTM":"2021-02-19 20:00:41","TRT02EDTM":"2022-02-20 02:00:41","AP01SDTM":"2019-06-06 02:47:09","AP01EDTM":"2021-02-19 20:00:41","AP02SDTM":"2021-02-19 20:00:41","AP02EDTM":"2022-02-20 02:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":990,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1027,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":270,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.43587,"AVALU":"U/L","BASE2":11.87974,"BASE":28.35326,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.55613,"PCHG2":46.76982,"CHG":-10.9174,"PCHG":-38.5049,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-12 02:47:09","ADY":494,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-178","SUBJID":"id-178","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.32131,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-06","TRTSDTM":"2019-06-06 02:47:09","TRTEDTM":"2022-02-20 02:00:41","TRT01SDTM":"2019-06-06 02:47:09","TRT01EDTM":"2021-02-19 20:00:41","TRT02SDTM":"2021-02-19 20:00:41","TRT02EDTM":"2022-02-20 02:00:41","AP01SDTM":"2019-06-06 02:47:09","AP01EDTM":"2021-02-19 20:00:41","AP02SDTM":"2021-02-19 20:00:41","AP02EDTM":"2022-02-20 02:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":990,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1027,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6009,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.83467,"AVALU":"U/L","BASE2":11.87974,"BASE":28.35326,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.95493,"PCHG2":125.88605,"CHG":-1.5186,"PCHG":-5.35599,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-02 02:47:09","ADY":727,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-178","SUBJID":"id-178","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.32131,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-06","TRTSDTM":"2019-06-06 02:47:09","TRTEDTM":"2022-02-20 02:00:41","TRT01SDTM":"2019-06-06 02:47:09","TRT01EDTM":"2021-02-19 20:00:41","TRT02SDTM":"2021-02-19 20:00:41","TRT02EDTM":"2022-02-20 02:00:41","AP01SDTM":"2019-06-06 02:47:09","AP01EDTM":"2021-02-19 20:00:41","AP02SDTM":"2021-02-19 20:00:41","AP02EDTM":"2022-02-20 02:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":990,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1027,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2908,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.19259,"AVALU":"U/L","BASE2":11.87974,"BASE":28.35326,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.31285,"PCHG2":44.72199,"CHG":-11.16067,"PCHG":-39.36292,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-15 02:47:09","ADY":985,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-178","SUBJID":"id-178","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.32131,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-06","TRTSDTM":"2019-06-06 02:47:09","TRTEDTM":"2022-02-20 02:00:41","TRT01SDTM":"2019-06-06 02:47:09","TRT01EDTM":"2021-02-19 20:00:41","TRT02SDTM":"2021-02-19 20:00:41","TRT02EDTM":"2022-02-20 02:00:41","AP01SDTM":"2019-06-06 02:47:09","AP01EDTM":"2021-02-19 20:00:41","AP02SDTM":"2021-02-19 20:00:41","AP02EDTM":"2022-02-20 02:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":990,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1027,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5374,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.46376,"AVALU":"mg/L","BASE2":9.46376,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-30 02:47:09","ADY":85,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-178","SUBJID":"id-178","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.32131,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-06","TRTSDTM":"2019-06-06 02:47:09","TRTEDTM":"2022-02-20 02:00:41","TRT01SDTM":"2019-06-06 02:47:09","TRT01EDTM":"2021-02-19 20:00:41","TRT02SDTM":"2021-02-19 20:00:41","TRT02EDTM":"2022-02-20 02:00:41","AP01SDTM":"2019-06-06 02:47:09","AP01EDTM":"2021-02-19 20:00:41","AP02SDTM":"2021-02-19 20:00:41","AP02EDTM":"2022-02-20 02:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":990,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1027,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2024,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.44717,"AVALU":"mg/L","BASE2":9.46376,"BASE":9.44717,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.01659,"PCHG2":-0.1753,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-28 02:47:09","ADY":144,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-178","SUBJID":"id-178","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.32131,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-06","TRTSDTM":"2019-06-06 02:47:09","TRTEDTM":"2022-02-20 02:00:41","TRT01SDTM":"2019-06-06 02:47:09","TRT01EDTM":"2021-02-19 20:00:41","TRT02SDTM":"2021-02-19 20:00:41","TRT02EDTM":"2022-02-20 02:00:41","AP01SDTM":"2019-06-06 02:47:09","AP01EDTM":"2021-02-19 20:00:41","AP02SDTM":"2021-02-19 20:00:41","AP02EDTM":"2022-02-20 02:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":990,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1027,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6669,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.60826,"AVALU":"mg/L","BASE2":9.46376,"BASE":9.44717,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1445,"PCHG2":1.52686,"CHG":0.16109,"PCHG":1.70514,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-10 02:47:09","ADY":431,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-178","SUBJID":"id-178","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.32131,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-06","TRTSDTM":"2019-06-06 02:47:09","TRTEDTM":"2022-02-20 02:00:41","TRT01SDTM":"2019-06-06 02:47:09","TRT01EDTM":"2021-02-19 20:00:41","TRT02SDTM":"2021-02-19 20:00:41","TRT02EDTM":"2022-02-20 02:00:41","AP01SDTM":"2019-06-06 02:47:09","AP01EDTM":"2021-02-19 20:00:41","AP02SDTM":"2021-02-19 20:00:41","AP02EDTM":"2022-02-20 02:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":990,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1027,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2744,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.25993,"AVALU":"mg/L","BASE2":9.46376,"BASE":9.44717,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20383,"PCHG2":-2.15379,"CHG":-0.18724,"PCHG":-1.98196,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-21 02:47:09","ADY":473,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-178","SUBJID":"id-178","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.32131,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-06","TRTSDTM":"2019-06-06 02:47:09","TRTEDTM":"2022-02-20 02:00:41","TRT01SDTM":"2019-06-06 02:47:09","TRT01EDTM":"2021-02-19 20:00:41","TRT02SDTM":"2021-02-19 20:00:41","TRT02EDTM":"2022-02-20 02:00:41","AP01SDTM":"2019-06-06 02:47:09","AP01EDTM":"2021-02-19 20:00:41","AP02SDTM":"2021-02-19 20:00:41","AP02EDTM":"2022-02-20 02:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":990,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1027,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1779,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.32412,"AVALU":"mg/L","BASE2":9.46376,"BASE":9.44717,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13964,"PCHG2":-1.47553,"CHG":-0.12305,"PCHG":-1.30252,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-12 02:47:09","ADY":494,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-178","SUBJID":"id-178","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.32131,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-06","TRTSDTM":"2019-06-06 02:47:09","TRTEDTM":"2022-02-20 02:00:41","TRT01SDTM":"2019-06-06 02:47:09","TRT01EDTM":"2021-02-19 20:00:41","TRT02SDTM":"2021-02-19 20:00:41","TRT02EDTM":"2022-02-20 02:00:41","AP01SDTM":"2019-06-06 02:47:09","AP01EDTM":"2021-02-19 20:00:41","AP02SDTM":"2021-02-19 20:00:41","AP02EDTM":"2022-02-20 02:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":990,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1027,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6922,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.7524,"AVALU":"mg/L","BASE2":9.46376,"BASE":9.44717,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.71136,"PCHG2":-18.08334,"CHG":-1.69477,"PCHG":-17.93949,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-06-02 02:47:09","ADY":727,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-178","SUBJID":"id-178","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.32131,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-06","TRTSDTM":"2019-06-06 02:47:09","TRTEDTM":"2022-02-20 02:00:41","TRT01SDTM":"2019-06-06 02:47:09","TRT01EDTM":"2021-02-19 20:00:41","TRT02SDTM":"2021-02-19 20:00:41","TRT02EDTM":"2022-02-20 02:00:41","AP01SDTM":"2019-06-06 02:47:09","AP01EDTM":"2021-02-19 20:00:41","AP02SDTM":"2021-02-19 20:00:41","AP02EDTM":"2022-02-20 02:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":990,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1027,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2240,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.45401,"AVALU":"mg/L","BASE2":9.46376,"BASE":9.44717,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.00975,"PCHG2":-10.66966,"CHG":-0.99316,"PCHG":-10.51279,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-15 02:47:09","ADY":985,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-178","SUBJID":"id-178","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.32131,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-06","TRTSDTM":"2019-06-06 02:47:09","TRTEDTM":"2022-02-20 02:00:41","TRT01SDTM":"2019-06-06 02:47:09","TRT01EDTM":"2021-02-19 20:00:41","TRT02SDTM":"2021-02-19 20:00:41","TRT02EDTM":"2022-02-20 02:00:41","AP01SDTM":"2019-06-06 02:47:09","AP01EDTM":"2021-02-19 20:00:41","AP02SDTM":"2021-02-19 20:00:41","AP02EDTM":"2022-02-20 02:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":990,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1027,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2544,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92963,"AVALU":"g/L","BASE2":2.92963,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-30 02:47:09","ADY":85,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-178","SUBJID":"id-178","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.32131,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-06","TRTSDTM":"2019-06-06 02:47:09","TRTEDTM":"2022-02-20 02:00:41","TRT01SDTM":"2019-06-06 02:47:09","TRT01EDTM":"2021-02-19 20:00:41","TRT02SDTM":"2021-02-19 20:00:41","TRT02EDTM":"2022-02-20 02:00:41","AP01SDTM":"2019-06-06 02:47:09","AP01EDTM":"2021-02-19 20:00:41","AP02SDTM":"2021-02-19 20:00:41","AP02EDTM":"2022-02-20 02:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":990,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1027,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1428,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94753,"AVALU":"g/L","BASE2":2.92963,"BASE":2.94753,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.01791,"PCHG2":0.61119,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-28 02:47:09","ADY":144,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-178","SUBJID":"id-178","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.32131,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-06","TRTSDTM":"2019-06-06 02:47:09","TRTEDTM":"2022-02-20 02:00:41","TRT01SDTM":"2019-06-06 02:47:09","TRT01EDTM":"2021-02-19 20:00:41","TRT02SDTM":"2021-02-19 20:00:41","TRT02EDTM":"2022-02-20 02:00:41","AP01SDTM":"2019-06-06 02:47:09","AP01EDTM":"2021-02-19 20:00:41","AP02SDTM":"2021-02-19 20:00:41","AP02EDTM":"2022-02-20 02:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":990,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1027,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2818,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78452,"AVALU":"g/L","BASE2":2.92963,"BASE":2.94753,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14511,"PCHG2":-4.95312,"CHG":-0.16301,"PCHG":-5.53051,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-10 02:47:09","ADY":431,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-178","SUBJID":"id-178","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.32131,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-06","TRTSDTM":"2019-06-06 02:47:09","TRTEDTM":"2022-02-20 02:00:41","TRT01SDTM":"2019-06-06 02:47:09","TRT01EDTM":"2021-02-19 20:00:41","TRT02SDTM":"2021-02-19 20:00:41","TRT02EDTM":"2022-02-20 02:00:41","AP01SDTM":"2019-06-06 02:47:09","AP01EDTM":"2021-02-19 20:00:41","AP02SDTM":"2021-02-19 20:00:41","AP02EDTM":"2022-02-20 02:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":990,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1027,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3528,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87952,"AVALU":"g/L","BASE2":2.92963,"BASE":2.94753,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05011,"PCHG2":-1.71041,"CHG":-0.06801,"PCHG":-2.3075,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-21 02:47:09","ADY":473,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-178","SUBJID":"id-178","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.32131,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-06","TRTSDTM":"2019-06-06 02:47:09","TRTEDTM":"2022-02-20 02:00:41","TRT01SDTM":"2019-06-06 02:47:09","TRT01EDTM":"2021-02-19 20:00:41","TRT02SDTM":"2021-02-19 20:00:41","TRT02EDTM":"2022-02-20 02:00:41","AP01SDTM":"2019-06-06 02:47:09","AP01EDTM":"2021-02-19 20:00:41","AP02SDTM":"2021-02-19 20:00:41","AP02EDTM":"2022-02-20 02:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":990,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1027,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":742,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80549,"AVALU":"g/L","BASE2":2.92963,"BASE":2.94753,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12414,"PCHG2":-4.23746,"CHG":-0.14205,"PCHG":-4.81919,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-12 02:47:09","ADY":494,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-178","SUBJID":"id-178","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.32131,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-06","TRTSDTM":"2019-06-06 02:47:09","TRTEDTM":"2022-02-20 02:00:41","TRT01SDTM":"2019-06-06 02:47:09","TRT01EDTM":"2021-02-19 20:00:41","TRT02SDTM":"2021-02-19 20:00:41","TRT02EDTM":"2022-02-20 02:00:41","AP01SDTM":"2019-06-06 02:47:09","AP01EDTM":"2021-02-19 20:00:41","AP02SDTM":"2021-02-19 20:00:41","AP02EDTM":"2022-02-20 02:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":990,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1027,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4299,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04016,"AVALU":"g/L","BASE2":2.92963,"BASE":2.94753,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11053,"PCHG2":3.77285,"CHG":0.09262,"PCHG":3.14245,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-06-02 02:47:09","ADY":727,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-178","SUBJID":"id-178","SITEID":"PAK-1","AGE":46,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":5.32131,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-06","TRTSDTM":"2019-06-06 02:47:09","TRTEDTM":"2022-02-20 02:00:41","TRT01SDTM":"2019-06-06 02:47:09","TRT01EDTM":"2021-02-19 20:00:41","TRT02SDTM":"2021-02-19 20:00:41","TRT02EDTM":"2022-02-20 02:00:41","AP01SDTM":"2019-06-06 02:47:09","AP01EDTM":"2021-02-19 20:00:41","AP02SDTM":"2021-02-19 20:00:41","AP02EDTM":"2022-02-20 02:00:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":990,"DCSREAS":"DEATH","DTHDT":"2022-03-30","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":38,"LDDTHGR1":">30","LSTALVDT":"2022-03-30","DTHADY":1027,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7246,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88654,"AVALU":"g/L","BASE2":2.92963,"BASE":2.94753,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04309,"PCHG2":-1.47095,"CHG":-0.061,"PCHG":-2.0695,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-15 02:47:09","ADY":985,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-280","SUBJID":"id-280","SITEID":"PAK-1","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.96261,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-28 21:30:08","TRTEDTM":"2022-02-14 18:11:59","TRT01SDTM":"2019-05-28 21:30:08","TRT01EDTM":"2021-02-14 12:11:59","TRT02SDTM":"2021-02-14 12:11:59","TRT02EDTM":"2022-02-14 18:11:59","AP01SDTM":"2019-05-28 21:30:08","AP01EDTM":"2021-02-14 12:11:59","AP02SDTM":"2021-02-14 12:11:59","AP02EDTM":"2022-02-14 18:11:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":993,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-14","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4855,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.87654,"AVALU":"U/L","BASE2":16.87654,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-10 21:30:08","ADY":105,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-280","SUBJID":"id-280","SITEID":"PAK-1","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.96261,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-28 21:30:08","TRTEDTM":"2022-02-14 18:11:59","TRT01SDTM":"2019-05-28 21:30:08","TRT01EDTM":"2021-02-14 12:11:59","TRT02SDTM":"2021-02-14 12:11:59","TRT02EDTM":"2022-02-14 18:11:59","AP01SDTM":"2019-05-28 21:30:08","AP01EDTM":"2021-02-14 12:11:59","AP02SDTM":"2021-02-14 12:11:59","AP02EDTM":"2022-02-14 18:11:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":993,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-14","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5624,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.44428,"AVALU":"U/L","BASE2":16.87654,"BASE":15.44428,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.43225,"PCHG2":-8.48666,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-07 21:30:08","ADY":345,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-280","SUBJID":"id-280","SITEID":"PAK-1","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.96261,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-28 21:30:08","TRTEDTM":"2022-02-14 18:11:59","TRT01SDTM":"2019-05-28 21:30:08","TRT01EDTM":"2021-02-14 12:11:59","TRT02SDTM":"2021-02-14 12:11:59","TRT02EDTM":"2022-02-14 18:11:59","AP01SDTM":"2019-05-28 21:30:08","AP01EDTM":"2021-02-14 12:11:59","AP02SDTM":"2021-02-14 12:11:59","AP02EDTM":"2022-02-14 18:11:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":993,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-14","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2161,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.09141,"AVALU":"U/L","BASE2":16.87654,"BASE":15.44428,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.21487,"PCHG2":48.67629,"CHG":9.64713,"PCHG":62.46407,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-05 21:30:08","ADY":527,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-280","SUBJID":"id-280","SITEID":"PAK-1","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.96261,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-28 21:30:08","TRTEDTM":"2022-02-14 18:11:59","TRT01SDTM":"2019-05-28 21:30:08","TRT01EDTM":"2021-02-14 12:11:59","TRT02SDTM":"2021-02-14 12:11:59","TRT02EDTM":"2022-02-14 18:11:59","AP01SDTM":"2019-05-28 21:30:08","AP01EDTM":"2021-02-14 12:11:59","AP02SDTM":"2021-02-14 12:11:59","AP02EDTM":"2022-02-14 18:11:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":993,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-14","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4719,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.39426,"AVALU":"U/L","BASE2":16.87654,"BASE":15.44428,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.48228,"PCHG2":-14.70847,"CHG":-1.05003,"PCHG":-6.79881,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-29 21:30:08","ADY":551,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-280","SUBJID":"id-280","SITEID":"PAK-1","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.96261,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-28 21:30:08","TRTEDTM":"2022-02-14 18:11:59","TRT01SDTM":"2019-05-28 21:30:08","TRT01EDTM":"2021-02-14 12:11:59","TRT02SDTM":"2021-02-14 12:11:59","TRT02EDTM":"2022-02-14 18:11:59","AP01SDTM":"2019-05-28 21:30:08","AP01EDTM":"2021-02-14 12:11:59","AP02SDTM":"2021-02-14 12:11:59","AP02EDTM":"2022-02-14 18:11:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":993,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-14","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7052,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":38.50353,"AVALU":"U/L","BASE2":16.87654,"BASE":15.44428,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":21.62699,"PCHG2":128.14827,"CHG":23.05925,"PCHG":149.30602,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-12 21:30:08","ADY":564,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-280","SUBJID":"id-280","SITEID":"PAK-1","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.96261,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-28 21:30:08","TRTEDTM":"2022-02-14 18:11:59","TRT01SDTM":"2019-05-28 21:30:08","TRT01EDTM":"2021-02-14 12:11:59","TRT02SDTM":"2021-02-14 12:11:59","TRT02EDTM":"2022-02-14 18:11:59","AP01SDTM":"2019-05-28 21:30:08","AP01EDTM":"2021-02-14 12:11:59","AP02SDTM":"2021-02-14 12:11:59","AP02EDTM":"2022-02-14 18:11:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":993,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-14","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6341,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.85676,"AVALU":"U/L","BASE2":16.87654,"BASE":15.44428,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.01978,"PCHG2":-59.37104,"CHG":-8.58752,"PCHG":-55.60324,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-01-26 21:30:08","ADY":609,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-280","SUBJID":"id-280","SITEID":"PAK-1","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.96261,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-28 21:30:08","TRTEDTM":"2022-02-14 18:11:59","TRT01SDTM":"2019-05-28 21:30:08","TRT01EDTM":"2021-02-14 12:11:59","TRT02SDTM":"2021-02-14 12:11:59","TRT02EDTM":"2022-02-14 18:11:59","AP01SDTM":"2019-05-28 21:30:08","AP01EDTM":"2021-02-14 12:11:59","AP02SDTM":"2021-02-14 12:11:59","AP02EDTM":"2022-02-14 18:11:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":993,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-14","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1178,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.74994,"AVALU":"U/L","BASE2":16.87654,"BASE":15.44428,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.8734,"PCHG2":58.50369,"CHG":11.30565,"PCHG":73.20283,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-06 21:30:08","ADY":862,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-280","SUBJID":"id-280","SITEID":"PAK-1","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.96261,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-28 21:30:08","TRTEDTM":"2022-02-14 18:11:59","TRT01SDTM":"2019-05-28 21:30:08","TRT01EDTM":"2021-02-14 12:11:59","TRT02SDTM":"2021-02-14 12:11:59","TRT02EDTM":"2022-02-14 18:11:59","AP01SDTM":"2019-05-28 21:30:08","AP01EDTM":"2021-02-14 12:11:59","AP02SDTM":"2021-02-14 12:11:59","AP02EDTM":"2022-02-14 18:11:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":993,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-14","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2930,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.02701,"AVALU":"mg/L","BASE2":9.02701,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-10 21:30:08","ADY":105,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-280","SUBJID":"id-280","SITEID":"PAK-1","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.96261,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-28 21:30:08","TRTEDTM":"2022-02-14 18:11:59","TRT01SDTM":"2019-05-28 21:30:08","TRT01EDTM":"2021-02-14 12:11:59","TRT02SDTM":"2021-02-14 12:11:59","TRT02EDTM":"2022-02-14 18:11:59","AP01SDTM":"2019-05-28 21:30:08","AP01EDTM":"2021-02-14 12:11:59","AP02SDTM":"2021-02-14 12:11:59","AP02EDTM":"2022-02-14 18:11:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":993,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-14","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5341,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.08627,"AVALU":"mg/L","BASE2":9.02701,"BASE":9.08627,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.05926,"PCHG2":0.65643,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-07 21:30:08","ADY":345,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-280","SUBJID":"id-280","SITEID":"PAK-1","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.96261,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-28 21:30:08","TRTEDTM":"2022-02-14 18:11:59","TRT01SDTM":"2019-05-28 21:30:08","TRT01EDTM":"2021-02-14 12:11:59","TRT02SDTM":"2021-02-14 12:11:59","TRT02EDTM":"2022-02-14 18:11:59","AP01SDTM":"2019-05-28 21:30:08","AP01EDTM":"2021-02-14 12:11:59","AP02SDTM":"2021-02-14 12:11:59","AP02EDTM":"2022-02-14 18:11:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":993,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-14","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":943,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.64631,"AVALU":"mg/L","BASE2":9.02701,"BASE":9.08627,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.3807,"PCHG2":-15.29522,"CHG":-1.43996,"PCHG":-15.84762,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-11-05 21:30:08","ADY":527,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-280","SUBJID":"id-280","SITEID":"PAK-1","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.96261,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-28 21:30:08","TRTEDTM":"2022-02-14 18:11:59","TRT01SDTM":"2019-05-28 21:30:08","TRT01EDTM":"2021-02-14 12:11:59","TRT02SDTM":"2021-02-14 12:11:59","TRT02EDTM":"2022-02-14 18:11:59","AP01SDTM":"2019-05-28 21:30:08","AP01EDTM":"2021-02-14 12:11:59","AP02SDTM":"2021-02-14 12:11:59","AP02EDTM":"2022-02-14 18:11:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":993,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-14","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":723,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.59392,"AVALU":"mg/L","BASE2":9.02701,"BASE":9.08627,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.43308,"PCHG2":-4.79766,"CHG":-0.49234,"PCHG":-5.41852,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-29 21:30:08","ADY":551,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-280","SUBJID":"id-280","SITEID":"PAK-1","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.96261,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-28 21:30:08","TRTEDTM":"2022-02-14 18:11:59","TRT01SDTM":"2019-05-28 21:30:08","TRT01EDTM":"2021-02-14 12:11:59","TRT02SDTM":"2021-02-14 12:11:59","TRT02EDTM":"2022-02-14 18:11:59","AP01SDTM":"2019-05-28 21:30:08","AP01EDTM":"2021-02-14 12:11:59","AP02SDTM":"2021-02-14 12:11:59","AP02EDTM":"2022-02-14 18:11:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":993,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-14","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7196,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.27727,"AVALU":"mg/L","BASE2":9.02701,"BASE":9.08627,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.25026,"PCHG2":2.77232,"CHG":0.191,"PCHG":2.10209,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-12 21:30:08","ADY":564,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-280","SUBJID":"id-280","SITEID":"PAK-1","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.96261,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-28 21:30:08","TRTEDTM":"2022-02-14 18:11:59","TRT01SDTM":"2019-05-28 21:30:08","TRT01EDTM":"2021-02-14 12:11:59","TRT02SDTM":"2021-02-14 12:11:59","TRT02EDTM":"2022-02-14 18:11:59","AP01SDTM":"2019-05-28 21:30:08","AP01EDTM":"2021-02-14 12:11:59","AP02SDTM":"2021-02-14 12:11:59","AP02EDTM":"2022-02-14 18:11:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":993,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-14","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5043,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.01864,"AVALU":"mg/L","BASE2":9.02701,"BASE":9.08627,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.99163,"PCHG2":10.98512,"CHG":0.93237,"PCHG":10.26133,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-01-26 21:30:08","ADY":609,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-280","SUBJID":"id-280","SITEID":"PAK-1","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.96261,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-28 21:30:08","TRTEDTM":"2022-02-14 18:11:59","TRT01SDTM":"2019-05-28 21:30:08","TRT01EDTM":"2021-02-14 12:11:59","TRT02SDTM":"2021-02-14 12:11:59","TRT02EDTM":"2022-02-14 18:11:59","AP01SDTM":"2019-05-28 21:30:08","AP01EDTM":"2021-02-14 12:11:59","AP02SDTM":"2021-02-14 12:11:59","AP02EDTM":"2022-02-14 18:11:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":993,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-14","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8172,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.90945,"AVALU":"mg/L","BASE2":9.02701,"BASE":9.08627,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.88244,"PCHG2":9.77552,"CHG":0.82318,"PCHG":9.05962,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-06 21:30:08","ADY":862,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-280","SUBJID":"id-280","SITEID":"PAK-1","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.96261,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-28 21:30:08","TRTEDTM":"2022-02-14 18:11:59","TRT01SDTM":"2019-05-28 21:30:08","TRT01EDTM":"2021-02-14 12:11:59","TRT02SDTM":"2021-02-14 12:11:59","TRT02EDTM":"2022-02-14 18:11:59","AP01SDTM":"2019-05-28 21:30:08","AP01EDTM":"2021-02-14 12:11:59","AP02SDTM":"2021-02-14 12:11:59","AP02EDTM":"2022-02-14 18:11:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":993,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-14","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6359,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85917,"AVALU":"g/L","BASE2":2.85917,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2019-09-10 21:30:08","ADY":105,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-280","SUBJID":"id-280","SITEID":"PAK-1","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.96261,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-28 21:30:08","TRTEDTM":"2022-02-14 18:11:59","TRT01SDTM":"2019-05-28 21:30:08","TRT01EDTM":"2021-02-14 12:11:59","TRT02SDTM":"2021-02-14 12:11:59","TRT02EDTM":"2022-02-14 18:11:59","AP01SDTM":"2019-05-28 21:30:08","AP01EDTM":"2021-02-14 12:11:59","AP02SDTM":"2021-02-14 12:11:59","AP02EDTM":"2022-02-14 18:11:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":993,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-14","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3648,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.15335,"AVALU":"g/L","BASE2":2.85917,"BASE":3.15335,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.29418,"PCHG2":10.28887,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-05-07 21:30:08","ADY":345,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-280","SUBJID":"id-280","SITEID":"PAK-1","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.96261,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-28 21:30:08","TRTEDTM":"2022-02-14 18:11:59","TRT01SDTM":"2019-05-28 21:30:08","TRT01EDTM":"2021-02-14 12:11:59","TRT02SDTM":"2021-02-14 12:11:59","TRT02EDTM":"2022-02-14 18:11:59","AP01SDTM":"2019-05-28 21:30:08","AP01EDTM":"2021-02-14 12:11:59","AP02SDTM":"2021-02-14 12:11:59","AP02EDTM":"2022-02-14 18:11:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":993,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-14","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2264,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95808,"AVALU":"g/L","BASE2":2.85917,"BASE":3.15335,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09891,"PCHG2":3.45947,"CHG":-0.19526,"PCHG":-6.19228,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-11-05 21:30:08","ADY":527,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-280","SUBJID":"id-280","SITEID":"PAK-1","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.96261,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-28 21:30:08","TRTEDTM":"2022-02-14 18:11:59","TRT01SDTM":"2019-05-28 21:30:08","TRT01EDTM":"2021-02-14 12:11:59","TRT02SDTM":"2021-02-14 12:11:59","TRT02EDTM":"2022-02-14 18:11:59","AP01SDTM":"2019-05-28 21:30:08","AP01EDTM":"2021-02-14 12:11:59","AP02SDTM":"2021-02-14 12:11:59","AP02EDTM":"2022-02-14 18:11:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":993,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-14","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5398,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96413,"AVALU":"g/L","BASE2":2.85917,"BASE":3.15335,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10496,"PCHG2":3.67096,"CHG":-0.18922,"PCHG":-6.00052,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-11-29 21:30:08","ADY":551,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-280","SUBJID":"id-280","SITEID":"PAK-1","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.96261,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-28 21:30:08","TRTEDTM":"2022-02-14 18:11:59","TRT01SDTM":"2019-05-28 21:30:08","TRT01EDTM":"2021-02-14 12:11:59","TRT02SDTM":"2021-02-14 12:11:59","TRT02EDTM":"2022-02-14 18:11:59","AP01SDTM":"2019-05-28 21:30:08","AP01EDTM":"2021-02-14 12:11:59","AP02SDTM":"2021-02-14 12:11:59","AP02EDTM":"2022-02-14 18:11:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":993,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-14","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4544,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77626,"AVALU":"g/L","BASE2":2.85917,"BASE":3.15335,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08292,"PCHG2":-2.89997,"CHG":-0.37709,"PCHG":-11.95845,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-12-12 21:30:08","ADY":564,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-280","SUBJID":"id-280","SITEID":"PAK-1","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.96261,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-28 21:30:08","TRTEDTM":"2022-02-14 18:11:59","TRT01SDTM":"2019-05-28 21:30:08","TRT01EDTM":"2021-02-14 12:11:59","TRT02SDTM":"2021-02-14 12:11:59","TRT02EDTM":"2022-02-14 18:11:59","AP01SDTM":"2019-05-28 21:30:08","AP01EDTM":"2021-02-14 12:11:59","AP02SDTM":"2021-02-14 12:11:59","AP02EDTM":"2022-02-14 18:11:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":993,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-14","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1577,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87104,"AVALU":"g/L","BASE2":2.85917,"BASE":3.15335,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01187,"PCHG2":0.41529,"CHG":-0.2823,"PCHG":-8.95247,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-01-26 21:30:08","ADY":609,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-280","SUBJID":"id-280","SITEID":"PAK-1","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.96261,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-05-26","TRTSDTM":"2019-05-28 21:30:08","TRTEDTM":"2022-02-14 18:11:59","TRT01SDTM":"2019-05-28 21:30:08","TRT01EDTM":"2021-02-14 12:11:59","TRT02SDTM":"2021-02-14 12:11:59","TRT02EDTM":"2022-02-14 18:11:59","AP01SDTM":"2019-05-28 21:30:08","AP01EDTM":"2021-02-14 12:11:59","AP02SDTM":"2021-02-14 12:11:59","AP02EDTM":"2022-02-14 18:11:59","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":993,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-14","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2093,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96012,"AVALU":"g/L","BASE2":2.85917,"BASE":3.15335,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10095,"PCHG2":3.53086,"CHG":-0.19322,"PCHG":-6.12755,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-10-06 21:30:08","ADY":862,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-39","SUBJID":"id-39","SITEID":"PAK-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.56183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-01","TRTSDTM":"2020-08-05 06:55:43","TRTEDTM":"2023-08-06 00:55:43","TRT01SDTM":"2020-08-05 06:55:43","TRT01EDTM":"2022-08-05 18:55:43","TRT02SDTM":"2022-08-05 18:55:43","TRT02EDTM":"2023-08-06 00:55:43","AP01SDTM":"2020-08-05 06:55:43","AP01EDTM":"2022-08-05 18:55:43","AP02SDTM":"2022-08-05 18:55:43","AP02EDTM":"2023-08-06 00:55:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-08-28","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1441,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.7637,"AVALU":"U/L","BASE2":21.7637,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-12 06:55:43","ADY":7,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-39","SUBJID":"id-39","SITEID":"PAK-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.56183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-01","TRTSDTM":"2020-08-05 06:55:43","TRTEDTM":"2023-08-06 00:55:43","TRT01SDTM":"2020-08-05 06:55:43","TRT01EDTM":"2022-08-05 18:55:43","TRT02SDTM":"2022-08-05 18:55:43","TRT02EDTM":"2023-08-06 00:55:43","AP01SDTM":"2020-08-05 06:55:43","AP01EDTM":"2022-08-05 18:55:43","AP02SDTM":"2022-08-05 18:55:43","AP02EDTM":"2023-08-06 00:55:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-08-28","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5784,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.96386,"AVALU":"U/L","BASE2":21.7637,"BASE":13.96386,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-7.79984,"PCHG2":-35.83877,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-18 06:55:43","ADY":74,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-39","SUBJID":"id-39","SITEID":"PAK-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.56183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-01","TRTSDTM":"2020-08-05 06:55:43","TRTEDTM":"2023-08-06 00:55:43","TRT01SDTM":"2020-08-05 06:55:43","TRT01EDTM":"2022-08-05 18:55:43","TRT02SDTM":"2022-08-05 18:55:43","TRT02EDTM":"2023-08-06 00:55:43","AP01SDTM":"2020-08-05 06:55:43","AP01EDTM":"2022-08-05 18:55:43","AP02SDTM":"2022-08-05 18:55:43","AP02EDTM":"2023-08-06 00:55:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-08-28","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":59,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.66283,"AVALU":"U/L","BASE2":21.7637,"BASE":13.96386,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-21.10087,"PCHG2":-96.95442,"CHG":-13.30103,"PCHG":-95.25324,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-01-08 06:55:43","ADY":521,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-39","SUBJID":"id-39","SITEID":"PAK-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.56183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-01","TRTSDTM":"2020-08-05 06:55:43","TRTEDTM":"2023-08-06 00:55:43","TRT01SDTM":"2020-08-05 06:55:43","TRT01EDTM":"2022-08-05 18:55:43","TRT02SDTM":"2022-08-05 18:55:43","TRT02EDTM":"2023-08-06 00:55:43","AP01SDTM":"2020-08-05 06:55:43","AP01EDTM":"2022-08-05 18:55:43","AP02SDTM":"2022-08-05 18:55:43","AP02EDTM":"2023-08-06 00:55:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-08-28","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6232,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.91165,"AVALU":"U/L","BASE2":21.7637,"BASE":13.96386,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.85206,"PCHG2":-82.02674,"CHG":-10.05221,"PCHG":-71.98735,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-02-11 06:55:43","ADY":555,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-39","SUBJID":"id-39","SITEID":"PAK-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.56183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-01","TRTSDTM":"2020-08-05 06:55:43","TRTEDTM":"2023-08-06 00:55:43","TRT01SDTM":"2020-08-05 06:55:43","TRT01EDTM":"2022-08-05 18:55:43","TRT02SDTM":"2022-08-05 18:55:43","TRT02EDTM":"2023-08-06 00:55:43","AP01SDTM":"2020-08-05 06:55:43","AP01EDTM":"2022-08-05 18:55:43","AP02SDTM":"2022-08-05 18:55:43","AP02EDTM":"2023-08-06 00:55:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-08-28","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6226,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.66348,"AVALU":"U/L","BASE2":21.7637,"BASE":13.96386,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.10023,"PCHG2":-37.21898,"CHG":-0.30038,"PCHG":-2.15115,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-06 06:55:43","ADY":762,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-39","SUBJID":"id-39","SITEID":"PAK-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.56183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-01","TRTSDTM":"2020-08-05 06:55:43","TRTEDTM":"2023-08-06 00:55:43","TRT01SDTM":"2020-08-05 06:55:43","TRT01EDTM":"2022-08-05 18:55:43","TRT02SDTM":"2022-08-05 18:55:43","TRT02EDTM":"2023-08-06 00:55:43","AP01SDTM":"2020-08-05 06:55:43","AP01EDTM":"2022-08-05 18:55:43","AP02SDTM":"2022-08-05 18:55:43","AP02EDTM":"2023-08-06 00:55:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-08-28","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5347,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.36952,"AVALU":"U/L","BASE2":21.7637,"BASE":13.96386,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.39418,"PCHG2":-66.13849,"CHG":-6.59434,"PCHG":-47.22434,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-24 06:55:43","ADY":933,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-39","SUBJID":"id-39","SITEID":"PAK-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.56183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-01","TRTSDTM":"2020-08-05 06:55:43","TRTEDTM":"2023-08-06 00:55:43","TRT01SDTM":"2020-08-05 06:55:43","TRT01EDTM":"2022-08-05 18:55:43","TRT02SDTM":"2022-08-05 18:55:43","TRT02EDTM":"2023-08-06 00:55:43","AP01SDTM":"2020-08-05 06:55:43","AP01EDTM":"2022-08-05 18:55:43","AP02SDTM":"2022-08-05 18:55:43","AP02EDTM":"2023-08-06 00:55:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-08-28","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6952,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.63022,"AVALU":"U/L","BASE2":21.7637,"BASE":13.96386,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.86652,"PCHG2":54.52435,"CHG":19.66636,"PCHG":140.83757,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-18 06:55:43","ADY":986,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-39","SUBJID":"id-39","SITEID":"PAK-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.56183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-01","TRTSDTM":"2020-08-05 06:55:43","TRTEDTM":"2023-08-06 00:55:43","TRT01SDTM":"2020-08-05 06:55:43","TRT01EDTM":"2022-08-05 18:55:43","TRT02SDTM":"2022-08-05 18:55:43","TRT02EDTM":"2023-08-06 00:55:43","AP01SDTM":"2020-08-05 06:55:43","AP01EDTM":"2022-08-05 18:55:43","AP02SDTM":"2022-08-05 18:55:43","AP02EDTM":"2023-08-06 00:55:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-08-28","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6629,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.30771,"AVALU":"mg/L","BASE2":8.30771,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-12 06:55:43","ADY":7,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-39","SUBJID":"id-39","SITEID":"PAK-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.56183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-01","TRTSDTM":"2020-08-05 06:55:43","TRTEDTM":"2023-08-06 00:55:43","TRT01SDTM":"2020-08-05 06:55:43","TRT01EDTM":"2022-08-05 18:55:43","TRT02SDTM":"2022-08-05 18:55:43","TRT02EDTM":"2023-08-06 00:55:43","AP01SDTM":"2020-08-05 06:55:43","AP01EDTM":"2022-08-05 18:55:43","AP02SDTM":"2022-08-05 18:55:43","AP02EDTM":"2023-08-06 00:55:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-08-28","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3148,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.512,"AVALU":"mg/L","BASE2":8.30771,"BASE":9.512,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.20428,"PCHG2":14.49599,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-18 06:55:43","ADY":74,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-39","SUBJID":"id-39","SITEID":"PAK-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.56183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-01","TRTSDTM":"2020-08-05 06:55:43","TRTEDTM":"2023-08-06 00:55:43","TRT01SDTM":"2020-08-05 06:55:43","TRT01EDTM":"2022-08-05 18:55:43","TRT02SDTM":"2022-08-05 18:55:43","TRT02EDTM":"2023-08-06 00:55:43","AP01SDTM":"2020-08-05 06:55:43","AP01EDTM":"2022-08-05 18:55:43","AP02SDTM":"2022-08-05 18:55:43","AP02EDTM":"2023-08-06 00:55:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-08-28","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2379,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.47373,"AVALU":"mg/L","BASE2":8.30771,"BASE":9.512,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.16602,"PCHG2":14.03535,"CHG":-0.03827,"PCHG":-0.40232,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-08 06:55:43","ADY":521,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-39","SUBJID":"id-39","SITEID":"PAK-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.56183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-01","TRTSDTM":"2020-08-05 06:55:43","TRTEDTM":"2023-08-06 00:55:43","TRT01SDTM":"2020-08-05 06:55:43","TRT01EDTM":"2022-08-05 18:55:43","TRT02SDTM":"2022-08-05 18:55:43","TRT02EDTM":"2023-08-06 00:55:43","AP01SDTM":"2020-08-05 06:55:43","AP01EDTM":"2022-08-05 18:55:43","AP02SDTM":"2022-08-05 18:55:43","AP02EDTM":"2023-08-06 00:55:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-08-28","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5969,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.74885,"AVALU":"mg/L","BASE2":8.30771,"BASE":9.512,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.55887,"PCHG2":-6.72708,"CHG":-1.76315,"PCHG":-18.53608,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2022-02-11 06:55:43","ADY":555,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-39","SUBJID":"id-39","SITEID":"PAK-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.56183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-01","TRTSDTM":"2020-08-05 06:55:43","TRTEDTM":"2023-08-06 00:55:43","TRT01SDTM":"2020-08-05 06:55:43","TRT01EDTM":"2022-08-05 18:55:43","TRT02SDTM":"2022-08-05 18:55:43","TRT02EDTM":"2023-08-06 00:55:43","AP01SDTM":"2020-08-05 06:55:43","AP01EDTM":"2022-08-05 18:55:43","AP02SDTM":"2022-08-05 18:55:43","AP02EDTM":"2023-08-06 00:55:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-08-28","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5376,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.37229,"AVALU":"mg/L","BASE2":8.30771,"BASE":9.512,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.06458,"PCHG2":24.85136,"CHG":0.86029,"PCHG":9.04431,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-09-06 06:55:43","ADY":762,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-39","SUBJID":"id-39","SITEID":"PAK-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.56183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-01","TRTSDTM":"2020-08-05 06:55:43","TRTEDTM":"2023-08-06 00:55:43","TRT01SDTM":"2020-08-05 06:55:43","TRT01EDTM":"2022-08-05 18:55:43","TRT02SDTM":"2022-08-05 18:55:43","TRT02EDTM":"2023-08-06 00:55:43","AP01SDTM":"2020-08-05 06:55:43","AP01EDTM":"2022-08-05 18:55:43","AP02SDTM":"2022-08-05 18:55:43","AP02EDTM":"2023-08-06 00:55:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-08-28","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4333,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.73684,"AVALU":"mg/L","BASE2":8.30771,"BASE":9.512,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.42912,"PCHG2":17.20237,"CHG":0.22484,"PCHG":2.36373,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-24 06:55:43","ADY":933,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-39","SUBJID":"id-39","SITEID":"PAK-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.56183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-01","TRTSDTM":"2020-08-05 06:55:43","TRTEDTM":"2023-08-06 00:55:43","TRT01SDTM":"2020-08-05 06:55:43","TRT01EDTM":"2022-08-05 18:55:43","TRT02SDTM":"2022-08-05 18:55:43","TRT02EDTM":"2023-08-06 00:55:43","AP01SDTM":"2020-08-05 06:55:43","AP01EDTM":"2022-08-05 18:55:43","AP02SDTM":"2022-08-05 18:55:43","AP02EDTM":"2023-08-06 00:55:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-08-28","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":509,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.18674,"AVALU":"mg/L","BASE2":8.30771,"BASE":9.512,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.87903,"PCHG2":10.58091,"CHG":-0.32525,"PCHG":-3.4194,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-18 06:55:43","ADY":986,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-39","SUBJID":"id-39","SITEID":"PAK-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.56183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-01","TRTSDTM":"2020-08-05 06:55:43","TRTEDTM":"2023-08-06 00:55:43","TRT01SDTM":"2020-08-05 06:55:43","TRT01EDTM":"2022-08-05 18:55:43","TRT02SDTM":"2022-08-05 18:55:43","TRT02EDTM":"2023-08-06 00:55:43","AP01SDTM":"2020-08-05 06:55:43","AP01EDTM":"2022-08-05 18:55:43","AP02SDTM":"2022-08-05 18:55:43","AP02EDTM":"2023-08-06 00:55:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-08-28","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7702,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.06917,"AVALU":"g/L","BASE2":3.06917,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-08-12 06:55:43","ADY":7,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-39","SUBJID":"id-39","SITEID":"PAK-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.56183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-01","TRTSDTM":"2020-08-05 06:55:43","TRTEDTM":"2023-08-06 00:55:43","TRT01SDTM":"2020-08-05 06:55:43","TRT01EDTM":"2022-08-05 18:55:43","TRT02SDTM":"2022-08-05 18:55:43","TRT02EDTM":"2023-08-06 00:55:43","AP01SDTM":"2020-08-05 06:55:43","AP01EDTM":"2022-08-05 18:55:43","AP02SDTM":"2022-08-05 18:55:43","AP02EDTM":"2023-08-06 00:55:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-08-28","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":166,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97057,"AVALU":"g/L","BASE2":3.06917,"BASE":2.97057,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.09861,"PCHG2":-3.2128,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-18 06:55:43","ADY":74,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-39","SUBJID":"id-39","SITEID":"PAK-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.56183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-01","TRTSDTM":"2020-08-05 06:55:43","TRTEDTM":"2023-08-06 00:55:43","TRT01SDTM":"2020-08-05 06:55:43","TRT01EDTM":"2022-08-05 18:55:43","TRT02SDTM":"2022-08-05 18:55:43","TRT02EDTM":"2023-08-06 00:55:43","AP01SDTM":"2020-08-05 06:55:43","AP01EDTM":"2022-08-05 18:55:43","AP02SDTM":"2022-08-05 18:55:43","AP02EDTM":"2023-08-06 00:55:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-08-28","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":223,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85619,"AVALU":"g/L","BASE2":3.06917,"BASE":2.97057,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21299,"PCHG2":-6.9395,"CHG":-0.11438,"PCHG":-3.85041,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-08 06:55:43","ADY":521,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-39","SUBJID":"id-39","SITEID":"PAK-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.56183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-01","TRTSDTM":"2020-08-05 06:55:43","TRTEDTM":"2023-08-06 00:55:43","TRT01SDTM":"2020-08-05 06:55:43","TRT01EDTM":"2022-08-05 18:55:43","TRT02SDTM":"2022-08-05 18:55:43","TRT02EDTM":"2023-08-06 00:55:43","AP01SDTM":"2020-08-05 06:55:43","AP01EDTM":"2022-08-05 18:55:43","AP02SDTM":"2022-08-05 18:55:43","AP02EDTM":"2023-08-06 00:55:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-08-28","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2752,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89793,"AVALU":"g/L","BASE2":3.06917,"BASE":2.97057,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17124,"PCHG2":-5.57937,"CHG":-0.07263,"PCHG":-2.44513,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-11 06:55:43","ADY":555,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-39","SUBJID":"id-39","SITEID":"PAK-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.56183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-01","TRTSDTM":"2020-08-05 06:55:43","TRTEDTM":"2023-08-06 00:55:43","TRT01SDTM":"2020-08-05 06:55:43","TRT01EDTM":"2022-08-05 18:55:43","TRT02SDTM":"2022-08-05 18:55:43","TRT02EDTM":"2023-08-06 00:55:43","AP01SDTM":"2020-08-05 06:55:43","AP01EDTM":"2022-08-05 18:55:43","AP02SDTM":"2022-08-05 18:55:43","AP02EDTM":"2023-08-06 00:55:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-08-28","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3892,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89506,"AVALU":"g/L","BASE2":3.06917,"BASE":2.97057,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17412,"PCHG2":-5.67312,"CHG":-0.07551,"PCHG":-2.54199,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-06 06:55:43","ADY":762,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-39","SUBJID":"id-39","SITEID":"PAK-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.56183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-01","TRTSDTM":"2020-08-05 06:55:43","TRTEDTM":"2023-08-06 00:55:43","TRT01SDTM":"2020-08-05 06:55:43","TRT01EDTM":"2022-08-05 18:55:43","TRT02SDTM":"2022-08-05 18:55:43","TRT02EDTM":"2023-08-06 00:55:43","AP01SDTM":"2020-08-05 06:55:43","AP01EDTM":"2022-08-05 18:55:43","AP02SDTM":"2022-08-05 18:55:43","AP02EDTM":"2023-08-06 00:55:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-08-28","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6989,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82285,"AVALU":"g/L","BASE2":3.06917,"BASE":2.97057,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.24633,"PCHG2":-8.02586,"CHG":-0.14772,"PCHG":-4.97283,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-24 06:55:43","ADY":933,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-39","SUBJID":"id-39","SITEID":"PAK-1","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":4.56183,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-01","TRTSDTM":"2020-08-05 06:55:43","TRTEDTM":"2023-08-06 00:55:43","TRT01SDTM":"2020-08-05 06:55:43","TRT01EDTM":"2022-08-05 18:55:43","TRT02SDTM":"2022-08-05 18:55:43","TRT02EDTM":"2023-08-06 00:55:43","AP01SDTM":"2020-08-05 06:55:43","AP01EDTM":"2022-08-05 18:55:43","AP02SDTM":"2022-08-05 18:55:43","AP02EDTM":"2023-08-06 00:55:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-06","EOSDY":1096,"LSTALVDT":"2023-08-28","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":336,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93959,"AVALU":"g/L","BASE2":3.06917,"BASE":2.97057,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12958,"PCHG2":-4.222,"CHG":-0.03097,"PCHG":-1.0427,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-18 06:55:43","ADY":986,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-79","SUBJID":"id-79","SITEID":"PAK-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.7217,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-22 03:05:33","TRT01SDTM":"2019-11-22 03:05:33","AP01SDTM":"2019-11-22 03:05:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":215,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.8408,"AVALU":"U/L","BASE2":6.8408,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-05-18 03:05:33","ADY":178,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-79","SUBJID":"id-79","SITEID":"PAK-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.7217,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-22 03:05:33","TRT01SDTM":"2019-11-22 03:05:33","AP01SDTM":"2019-11-22 03:05:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1140,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.90821,"AVALU":"U/L","BASE2":6.8408,"BASE":31.90821,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":25.06741,"PCHG2":366.43974,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-20 03:05:33","ADY":180,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-79","SUBJID":"id-79","SITEID":"PAK-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.7217,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-22 03:05:33","TRT01SDTM":"2019-11-22 03:05:33","AP01SDTM":"2019-11-22 03:05:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2043,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.85719,"AVALU":"U/L","BASE2":6.8408,"BASE":31.90821,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.01639,"PCHG2":234.13039,"CHG":-9.05102,"PCHG":-28.3658,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-11 03:05:33","ADY":202,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-79","SUBJID":"id-79","SITEID":"PAK-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.7217,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-22 03:05:33","TRT01SDTM":"2019-11-22 03:05:33","AP01SDTM":"2019-11-22 03:05:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8113,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.42077,"AVALU":"U/L","BASE2":6.8408,"BASE":31.90821,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":25.57997,"PCHG2":373.93254,"CHG":0.51257,"PCHG":1.60638,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-30 03:05:33","ADY":251,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-79","SUBJID":"id-79","SITEID":"PAK-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.7217,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-22 03:05:33","TRT01SDTM":"2019-11-22 03:05:33","AP01SDTM":"2019-11-22 03:05:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6112,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.98961,"AVALU":"U/L","BASE2":6.8408,"BASE":31.90821,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.14881,"PCHG2":148.35706,"CHG":-14.9186,"PCHG":-46.75474,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-01 03:05:33","ADY":253,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-79","SUBJID":"id-79","SITEID":"PAK-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.7217,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-22 03:05:33","TRT01SDTM":"2019-11-22 03:05:33","AP01SDTM":"2019-11-22 03:05:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1766,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.4686,"AVALU":"U/L","BASE2":6.8408,"BASE":31.90821,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.3722,"PCHG2":-34.67719,"CHG":-27.4396,"PCHG":-85.99544,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-03-10 03:05:33","ADY":474,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-79","SUBJID":"id-79","SITEID":"PAK-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.7217,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-22 03:05:33","TRT01SDTM":"2019-11-22 03:05:33","AP01SDTM":"2019-11-22 03:05:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6623,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.36773,"AVALU":"U/L","BASE2":6.8408,"BASE":31.90821,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.52693,"PCHG2":212.3572,"CHG":-10.54048,"PCHG":-33.03375,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-30 03:05:33","ADY":647,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-79","SUBJID":"id-79","SITEID":"PAK-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.7217,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-22 03:05:33","TRT01SDTM":"2019-11-22 03:05:33","AP01SDTM":"2019-11-22 03:05:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6137,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.14374,"AVALU":"mg/L","BASE2":7.14374,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-05-18 03:05:33","ADY":178,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-79","SUBJID":"id-79","SITEID":"PAK-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.7217,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-22 03:05:33","TRT01SDTM":"2019-11-22 03:05:33","AP01SDTM":"2019-11-22 03:05:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4761,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.02023,"AVALU":"mg/L","BASE2":7.14374,"BASE":8.02023,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.87649,"PCHG2":12.26936,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-20 03:05:33","ADY":180,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-79","SUBJID":"id-79","SITEID":"PAK-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.7217,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-22 03:05:33","TRT01SDTM":"2019-11-22 03:05:33","AP01SDTM":"2019-11-22 03:05:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":599,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.72581,"AVALU":"mg/L","BASE2":7.14374,"BASE":8.02023,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.58207,"PCHG2":8.14801,"CHG":-0.29442,"PCHG":-3.67094,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-06-11 03:05:33","ADY":202,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-79","SUBJID":"id-79","SITEID":"PAK-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.7217,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-22 03:05:33","TRT01SDTM":"2019-11-22 03:05:33","AP01SDTM":"2019-11-22 03:05:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8145,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.93968,"AVALU":"mg/L","BASE2":7.14374,"BASE":8.02023,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.79595,"PCHG2":25.14018,"CHG":0.91946,"PCHG":11.46424,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-30 03:05:33","ADY":251,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-79","SUBJID":"id-79","SITEID":"PAK-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.7217,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-22 03:05:33","TRT01SDTM":"2019-11-22 03:05:33","AP01SDTM":"2019-11-22 03:05:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7139,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.15272,"AVALU":"mg/L","BASE2":7.14374,"BASE":8.02023,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.00899,"PCHG2":14.12407,"CHG":0.1325,"PCHG":1.65202,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-01 03:05:33","ADY":253,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-79","SUBJID":"id-79","SITEID":"PAK-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.7217,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-22 03:05:33","TRT01SDTM":"2019-11-22 03:05:33","AP01SDTM":"2019-11-22 03:05:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1124,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.35322,"AVALU":"mg/L","BASE2":7.14374,"BASE":8.02023,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.20949,"PCHG2":16.93073,"CHG":0.333,"PCHG":4.15195,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-10 03:05:33","ADY":474,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-79","SUBJID":"id-79","SITEID":"PAK-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.7217,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-22 03:05:33","TRT01SDTM":"2019-11-22 03:05:33","AP01SDTM":"2019-11-22 03:05:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2657,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.31437,"AVALU":"mg/L","BASE2":7.14374,"BASE":8.02023,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.17063,"PCHG2":30.3851,"CHG":1.29414,"PCHG":16.13596,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-30 03:05:33","ADY":647,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-79","SUBJID":"id-79","SITEID":"PAK-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.7217,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-22 03:05:33","TRT01SDTM":"2019-11-22 03:05:33","AP01SDTM":"2019-11-22 03:05:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2073,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02766,"AVALU":"g/L","BASE2":3.02766,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-05-18 03:05:33","ADY":178,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-79","SUBJID":"id-79","SITEID":"PAK-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.7217,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-22 03:05:33","TRT01SDTM":"2019-11-22 03:05:33","AP01SDTM":"2019-11-22 03:05:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1378,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88777,"AVALU":"g/L","BASE2":3.02766,"BASE":2.88777,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.13989,"PCHG2":-4.62026,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-20 03:05:33","ADY":180,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-79","SUBJID":"id-79","SITEID":"PAK-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.7217,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-22 03:05:33","TRT01SDTM":"2019-11-22 03:05:33","AP01SDTM":"2019-11-22 03:05:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2797,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87387,"AVALU":"g/L","BASE2":3.02766,"BASE":2.88777,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15378,"PCHG2":-5.07933,"CHG":-0.0139,"PCHG":-0.48132,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-11 03:05:33","ADY":202,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-79","SUBJID":"id-79","SITEID":"PAK-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.7217,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-22 03:05:33","TRT01SDTM":"2019-11-22 03:05:33","AP01SDTM":"2019-11-22 03:05:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5144,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88682,"AVALU":"g/L","BASE2":3.02766,"BASE":2.88777,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14083,"PCHG2":-4.6516,"CHG":-0.00095,"PCHG":-0.03286,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-30 03:05:33","ADY":251,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-79","SUBJID":"id-79","SITEID":"PAK-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.7217,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-22 03:05:33","TRT01SDTM":"2019-11-22 03:05:33","AP01SDTM":"2019-11-22 03:05:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2585,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00462,"AVALU":"g/L","BASE2":3.02766,"BASE":2.88777,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02304,"PCHG2":-0.76089,"CHG":0.11685,"PCHG":4.04631,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-08-01 03:05:33","ADY":253,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-79","SUBJID":"id-79","SITEID":"PAK-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.7217,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-22 03:05:33","TRT01SDTM":"2019-11-22 03:05:33","AP01SDTM":"2019-11-22 03:05:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4986,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77374,"AVALU":"g/L","BASE2":3.02766,"BASE":2.88777,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.25392,"PCHG2":-8.38654,"CHG":-0.11403,"PCHG":-3.94873,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-10 03:05:33","ADY":474,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-79","SUBJID":"id-79","SITEID":"PAK-1","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.7217,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-11-18","TRTSDTM":"2019-11-22 03:05:33","TRT01SDTM":"2019-11-22 03:05:33","AP01SDTM":"2019-11-22 03:05:33","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3620,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88082,"AVALU":"g/L","BASE2":3.02766,"BASE":2.88777,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14683,"PCHG2":-4.84968,"CHG":-0.00695,"PCHG":-0.24054,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-30 03:05:33","ADY":647,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-95","SUBJID":"id-95","SITEID":"PAK-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.88673,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-01 02:20:10","TRTEDTM":"2022-02-18 07:22:15","TRT01SDTM":"2019-05-01 02:20:10","TRT01EDTM":"2021-02-18 01:22:15","TRT02SDTM":"2021-02-18 01:22:15","TRT02EDTM":"2022-02-18 07:22:15","AP01SDTM":"2019-05-01 02:20:10","AP01EDTM":"2021-02-18 01:22:15","AP02SDTM":"2021-02-18 01:22:15","AP02EDTM":"2022-02-18 07:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":4,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1027,"ADTHAUT":"No","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":277,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.46195,"AVALU":"U/L","BASE2":17.46195,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-06-08 02:20:10","ADY":38,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-95","SUBJID":"id-95","SITEID":"PAK-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.88673,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-01 02:20:10","TRTEDTM":"2022-02-18 07:22:15","TRT01SDTM":"2019-05-01 02:20:10","TRT01EDTM":"2021-02-18 01:22:15","TRT02SDTM":"2021-02-18 01:22:15","TRT02EDTM":"2022-02-18 07:22:15","AP01SDTM":"2019-05-01 02:20:10","AP01EDTM":"2021-02-18 01:22:15","AP02SDTM":"2021-02-18 01:22:15","AP02EDTM":"2022-02-18 07:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":4,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1027,"ADTHAUT":"No","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6856,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.61699,"AVALU":"U/L","BASE2":17.46195,"BASE":12.61699,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-4.84496,"PCHG2":-27.74582,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-04 02:20:10","ADY":64,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-95","SUBJID":"id-95","SITEID":"PAK-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.88673,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-01 02:20:10","TRTEDTM":"2022-02-18 07:22:15","TRT01SDTM":"2019-05-01 02:20:10","TRT01EDTM":"2021-02-18 01:22:15","TRT02SDTM":"2021-02-18 01:22:15","TRT02EDTM":"2022-02-18 07:22:15","AP01SDTM":"2019-05-01 02:20:10","AP01EDTM":"2021-02-18 01:22:15","AP02SDTM":"2021-02-18 01:22:15","AP02EDTM":"2022-02-18 07:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":4,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1027,"ADTHAUT":"No","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8060,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.06175,"AVALU":"U/L","BASE2":17.46195,"BASE":12.61699,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.5998,"PCHG2":3.43487,"CHG":5.44476,"PCHG":43.15416,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-29 02:20:10","ADY":212,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-95","SUBJID":"id-95","SITEID":"PAK-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.88673,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-01 02:20:10","TRTEDTM":"2022-02-18 07:22:15","TRT01SDTM":"2019-05-01 02:20:10","TRT01EDTM":"2021-02-18 01:22:15","TRT02SDTM":"2021-02-18 01:22:15","TRT02EDTM":"2022-02-18 07:22:15","AP01SDTM":"2019-05-01 02:20:10","AP01EDTM":"2021-02-18 01:22:15","AP02SDTM":"2021-02-18 01:22:15","AP02EDTM":"2022-02-18 07:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":4,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1027,"ADTHAUT":"No","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5543,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.05903,"AVALU":"U/L","BASE2":17.46195,"BASE":12.61699,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.59708,"PCHG2":9.14606,"CHG":6.44204,"PCHG":51.05846,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-27 02:20:10","ADY":423,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-95","SUBJID":"id-95","SITEID":"PAK-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.88673,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-01 02:20:10","TRTEDTM":"2022-02-18 07:22:15","TRT01SDTM":"2019-05-01 02:20:10","TRT01EDTM":"2021-02-18 01:22:15","TRT02SDTM":"2021-02-18 01:22:15","TRT02EDTM":"2022-02-18 07:22:15","AP01SDTM":"2019-05-01 02:20:10","AP01EDTM":"2021-02-18 01:22:15","AP02SDTM":"2021-02-18 01:22:15","AP02EDTM":"2022-02-18 07:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":4,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1027,"ADTHAUT":"No","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8326,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.5747,"AVALU":"U/L","BASE2":17.46195,"BASE":12.61699,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.88725,"PCHG2":-85.25539,"CHG":-10.04229,"PCHG":-79.59342,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-01-30 02:20:10","ADY":640,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-95","SUBJID":"id-95","SITEID":"PAK-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.88673,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-01 02:20:10","TRTEDTM":"2022-02-18 07:22:15","TRT01SDTM":"2019-05-01 02:20:10","TRT01EDTM":"2021-02-18 01:22:15","TRT02SDTM":"2021-02-18 01:22:15","TRT02EDTM":"2022-02-18 07:22:15","AP01SDTM":"2019-05-01 02:20:10","AP01EDTM":"2021-02-18 01:22:15","AP02SDTM":"2021-02-18 01:22:15","AP02EDTM":"2022-02-18 07:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":4,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1027,"ADTHAUT":"No","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7515,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.5385,"AVALU":"U/L","BASE2":17.46195,"BASE":12.61699,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.92345,"PCHG2":-16.74181,"CHG":1.92151,"PCHG":15.22957,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-26 02:20:10","ADY":726,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-95","SUBJID":"id-95","SITEID":"PAK-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.88673,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-01 02:20:10","TRTEDTM":"2022-02-18 07:22:15","TRT01SDTM":"2019-05-01 02:20:10","TRT01EDTM":"2021-02-18 01:22:15","TRT02SDTM":"2021-02-18 01:22:15","TRT02EDTM":"2022-02-18 07:22:15","AP01SDTM":"2019-05-01 02:20:10","AP01EDTM":"2021-02-18 01:22:15","AP02SDTM":"2021-02-18 01:22:15","AP02EDTM":"2022-02-18 07:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":4,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1027,"ADTHAUT":"No","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2003,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.22601,"AVALU":"U/L","BASE2":17.46195,"BASE":12.61699,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.23594,"PCHG2":-1.35114,"CHG":4.60902,"PCHG":36.5303,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-23 02:20:10","ADY":906,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-95","SUBJID":"id-95","SITEID":"PAK-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.88673,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-01 02:20:10","TRTEDTM":"2022-02-18 07:22:15","TRT01SDTM":"2019-05-01 02:20:10","TRT01EDTM":"2021-02-18 01:22:15","TRT02SDTM":"2021-02-18 01:22:15","TRT02EDTM":"2022-02-18 07:22:15","AP01SDTM":"2019-05-01 02:20:10","AP01EDTM":"2021-02-18 01:22:15","AP02SDTM":"2021-02-18 01:22:15","AP02EDTM":"2022-02-18 07:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":4,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1027,"ADTHAUT":"No","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7164,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.28332,"AVALU":"mg/L","BASE2":9.28332,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-3","ADTM":"2019-06-08 02:20:10","ADY":38,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-95","SUBJID":"id-95","SITEID":"PAK-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.88673,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-01 02:20:10","TRTEDTM":"2022-02-18 07:22:15","TRT01SDTM":"2019-05-01 02:20:10","TRT01EDTM":"2021-02-18 01:22:15","TRT02SDTM":"2021-02-18 01:22:15","TRT02EDTM":"2022-02-18 07:22:15","AP01SDTM":"2019-05-01 02:20:10","AP01EDTM":"2021-02-18 01:22:15","AP02SDTM":"2021-02-18 01:22:15","AP02EDTM":"2022-02-18 07:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":4,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1027,"ADTHAUT":"No","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3796,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.40492,"AVALU":"mg/L","BASE2":9.28332,"BASE":7.40492,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.87841,"PCHG2":-20.23419,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2019-07-04 02:20:10","ADY":64,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-95","SUBJID":"id-95","SITEID":"PAK-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.88673,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-01 02:20:10","TRTEDTM":"2022-02-18 07:22:15","TRT01SDTM":"2019-05-01 02:20:10","TRT01EDTM":"2021-02-18 01:22:15","TRT02SDTM":"2021-02-18 01:22:15","TRT02EDTM":"2022-02-18 07:22:15","AP01SDTM":"2019-05-01 02:20:10","AP01EDTM":"2021-02-18 01:22:15","AP02SDTM":"2021-02-18 01:22:15","AP02EDTM":"2022-02-18 07:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":4,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1027,"ADTHAUT":"No","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1683,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.26538,"AVALU":"mg/L","BASE2":9.28332,"BASE":7.40492,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01795,"PCHG2":-0.19332,"CHG":1.86046,"PCHG":25.12464,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2019-11-29 02:20:10","ADY":212,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-95","SUBJID":"id-95","SITEID":"PAK-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.88673,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-01 02:20:10","TRTEDTM":"2022-02-18 07:22:15","TRT01SDTM":"2019-05-01 02:20:10","TRT01EDTM":"2021-02-18 01:22:15","TRT02SDTM":"2021-02-18 01:22:15","TRT02EDTM":"2022-02-18 07:22:15","AP01SDTM":"2019-05-01 02:20:10","AP01EDTM":"2021-02-18 01:22:15","AP02SDTM":"2021-02-18 01:22:15","AP02EDTM":"2022-02-18 07:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":4,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1027,"ADTHAUT":"No","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3134,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.42424,"AVALU":"mg/L","BASE2":9.28332,"BASE":7.40492,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14092,"PCHG2":1.51798,"CHG":2.01932,"PCHG":27.27004,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2020-06-27 02:20:10","ADY":423,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-95","SUBJID":"id-95","SITEID":"PAK-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.88673,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-01 02:20:10","TRTEDTM":"2022-02-18 07:22:15","TRT01SDTM":"2019-05-01 02:20:10","TRT01EDTM":"2021-02-18 01:22:15","TRT02SDTM":"2021-02-18 01:22:15","TRT02EDTM":"2022-02-18 07:22:15","AP01SDTM":"2019-05-01 02:20:10","AP01EDTM":"2021-02-18 01:22:15","AP02SDTM":"2021-02-18 01:22:15","AP02EDTM":"2022-02-18 07:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":4,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1027,"ADTHAUT":"No","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1894,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.05005,"AVALU":"mg/L","BASE2":9.28332,"BASE":7.40492,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.23327,"PCHG2":-2.51278,"CHG":1.64514,"PCHG":22.21679,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-01-30 02:20:10","ADY":640,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-95","SUBJID":"id-95","SITEID":"PAK-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.88673,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-01 02:20:10","TRTEDTM":"2022-02-18 07:22:15","TRT01SDTM":"2019-05-01 02:20:10","TRT01EDTM":"2021-02-18 01:22:15","TRT02SDTM":"2021-02-18 01:22:15","TRT02EDTM":"2022-02-18 07:22:15","AP01SDTM":"2019-05-01 02:20:10","AP01EDTM":"2021-02-18 01:22:15","AP02SDTM":"2021-02-18 01:22:15","AP02EDTM":"2022-02-18 07:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":4,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1027,"ADTHAUT":"No","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5603,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.49769,"AVALU":"mg/L","BASE2":9.28332,"BASE":7.40492,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.78564,"PCHG2":-8.46288,"CHG":1.09277,"PCHG":14.75734,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-04-26 02:20:10","ADY":726,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-95","SUBJID":"id-95","SITEID":"PAK-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.88673,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-01 02:20:10","TRTEDTM":"2022-02-18 07:22:15","TRT01SDTM":"2019-05-01 02:20:10","TRT01EDTM":"2021-02-18 01:22:15","TRT02SDTM":"2021-02-18 01:22:15","TRT02EDTM":"2022-02-18 07:22:15","AP01SDTM":"2019-05-01 02:20:10","AP01EDTM":"2021-02-18 01:22:15","AP02SDTM":"2021-02-18 01:22:15","AP02EDTM":"2022-02-18 07:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":4,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1027,"ADTHAUT":"No","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3721,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.7795,"AVALU":"mg/L","BASE2":9.28332,"BASE":7.40492,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.50383,"PCHG2":-5.42724,"CHG":1.37458,"PCHG":18.56302,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-10-23 02:20:10","ADY":906,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-95","SUBJID":"id-95","SITEID":"PAK-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.88673,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-01 02:20:10","TRTEDTM":"2022-02-18 07:22:15","TRT01SDTM":"2019-05-01 02:20:10","TRT01EDTM":"2021-02-18 01:22:15","TRT02SDTM":"2021-02-18 01:22:15","TRT02EDTM":"2022-02-18 07:22:15","AP01SDTM":"2019-05-01 02:20:10","AP01EDTM":"2021-02-18 01:22:15","AP02SDTM":"2021-02-18 01:22:15","AP02EDTM":"2022-02-18 07:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":4,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1027,"ADTHAUT":"No","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5299,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.13711,"AVALU":"g/L","BASE2":3.13711,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"2","BTOXGR":"0","ADTM":"2019-06-08 02:20:10","ADY":38,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-95","SUBJID":"id-95","SITEID":"PAK-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.88673,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-01 02:20:10","TRTEDTM":"2022-02-18 07:22:15","TRT01SDTM":"2019-05-01 02:20:10","TRT01EDTM":"2021-02-18 01:22:15","TRT02SDTM":"2021-02-18 01:22:15","TRT02EDTM":"2022-02-18 07:22:15","AP01SDTM":"2019-05-01 02:20:10","AP01EDTM":"2021-02-18 01:22:15","AP02SDTM":"2021-02-18 01:22:15","AP02EDTM":"2022-02-18 07:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":4,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1027,"ADTHAUT":"No","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6558,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84114,"AVALU":"g/L","BASE2":3.13711,"BASE":2.84114,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.29597,"PCHG2":-9.43438,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-04 02:20:10","ADY":64,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-95","SUBJID":"id-95","SITEID":"PAK-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.88673,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-01 02:20:10","TRTEDTM":"2022-02-18 07:22:15","TRT01SDTM":"2019-05-01 02:20:10","TRT01EDTM":"2021-02-18 01:22:15","TRT02SDTM":"2021-02-18 01:22:15","TRT02EDTM":"2022-02-18 07:22:15","AP01SDTM":"2019-05-01 02:20:10","AP01EDTM":"2021-02-18 01:22:15","AP02SDTM":"2021-02-18 01:22:15","AP02EDTM":"2022-02-18 07:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":4,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1027,"ADTHAUT":"No","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1029,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86096,"AVALU":"g/L","BASE2":3.13711,"BASE":2.84114,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.27614,"PCHG2":-8.80246,"CHG":0.01982,"PCHG":0.69774,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-29 02:20:10","ADY":212,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-95","SUBJID":"id-95","SITEID":"PAK-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.88673,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-01 02:20:10","TRTEDTM":"2022-02-18 07:22:15","TRT01SDTM":"2019-05-01 02:20:10","TRT01EDTM":"2021-02-18 01:22:15","TRT02SDTM":"2021-02-18 01:22:15","TRT02EDTM":"2022-02-18 07:22:15","AP01SDTM":"2019-05-01 02:20:10","AP01EDTM":"2021-02-18 01:22:15","AP02SDTM":"2021-02-18 01:22:15","AP02EDTM":"2022-02-18 07:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":4,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1027,"ADTHAUT":"No","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7249,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89634,"AVALU":"g/L","BASE2":3.13711,"BASE":2.84114,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.24076,"PCHG2":-7.67471,"CHG":0.0552,"PCHG":1.94298,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-27 02:20:10","ADY":423,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-95","SUBJID":"id-95","SITEID":"PAK-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.88673,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-01 02:20:10","TRTEDTM":"2022-02-18 07:22:15","TRT01SDTM":"2019-05-01 02:20:10","TRT01EDTM":"2021-02-18 01:22:15","TRT02SDTM":"2021-02-18 01:22:15","TRT02EDTM":"2022-02-18 07:22:15","AP01SDTM":"2019-05-01 02:20:10","AP01EDTM":"2021-02-18 01:22:15","AP02SDTM":"2021-02-18 01:22:15","AP02EDTM":"2022-02-18 07:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":4,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1027,"ADTHAUT":"No","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3713,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92306,"AVALU":"g/L","BASE2":3.13711,"BASE":2.84114,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21405,"PCHG2":-6.82302,"CHG":0.08192,"PCHG":2.88339,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-30 02:20:10","ADY":640,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-95","SUBJID":"id-95","SITEID":"PAK-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.88673,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-01 02:20:10","TRTEDTM":"2022-02-18 07:22:15","TRT01SDTM":"2019-05-01 02:20:10","TRT01EDTM":"2021-02-18 01:22:15","TRT02SDTM":"2021-02-18 01:22:15","TRT02EDTM":"2022-02-18 07:22:15","AP01SDTM":"2019-05-01 02:20:10","AP01EDTM":"2021-02-18 01:22:15","AP02SDTM":"2021-02-18 01:22:15","AP02EDTM":"2022-02-18 07:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":4,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1027,"ADTHAUT":"No","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5778,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9721,"AVALU":"g/L","BASE2":3.13711,"BASE":2.84114,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16501,"PCHG2":-5.25998,"CHG":0.13096,"PCHG":4.60926,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-26 02:20:10","ADY":726,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-1-id-95","SUBJID":"id-95","SITEID":"PAK-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-1","INVNAM":"Dr. PAK-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.88673,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-01 02:20:10","TRTEDTM":"2022-02-18 07:22:15","TRT01SDTM":"2019-05-01 02:20:10","TRT01EDTM":"2021-02-18 01:22:15","TRT02SDTM":"2021-02-18 01:22:15","TRT02EDTM":"2022-02-18 07:22:15","AP01SDTM":"2019-05-01 02:20:10","AP01EDTM":"2021-02-18 01:22:15","AP02SDTM":"2021-02-18 01:22:15","AP02EDTM":"2022-02-18 07:22:15","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-18","EOSDY":1025,"DCSREAS":"DEATH","DTHDT":"2022-02-22","DTHCAUS":"Post-study reporting of death","DTHCAT":"OTHER","LDDTHELD":4,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-22","DTHADY":1027,"ADTHAUT":"No","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3554,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93669,"AVALU":"g/L","BASE2":3.13711,"BASE":2.84114,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20042,"PCHG2":-6.3886,"CHG":0.09555,"PCHG":3.36306,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-23 02:20:10","ADY":906,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-145","SUBJID":"id-145","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.20279,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-17 15:15:16","TRT01SDTM":"2020-01-17 15:15:16","AP01SDTM":"2020-01-17 15:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2587,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.68677,"AVALU":"U/L","BASE2":5.68677,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-01-18 15:15:16","ADY":1,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-145","SUBJID":"id-145","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.20279,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-17 15:15:16","TRT01SDTM":"2020-01-17 15:15:16","AP01SDTM":"2020-01-17 15:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7486,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.1849,"AVALU":"U/L","BASE2":5.68677,"BASE":11.1849,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":5.49814,"PCHG2":96.68306,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-10 15:15:16","ADY":84,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-145","SUBJID":"id-145","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.20279,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-17 15:15:16","TRT01SDTM":"2020-01-17 15:15:16","AP01SDTM":"2020-01-17 15:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2686,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.70141,"AVALU":"U/L","BASE2":5.68677,"BASE":11.1849,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":27.01465,"PCHG2":475.04414,"CHG":21.51651,"PCHG":192.37096,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-13 15:15:16","ADY":87,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-145","SUBJID":"id-145","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.20279,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-17 15:15:16","TRT01SDTM":"2020-01-17 15:15:16","AP01SDTM":"2020-01-17 15:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6284,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.5583,"AVALU":"U/L","BASE2":5.68677,"BASE":11.1849,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.87153,"PCHG2":120.83371,"CHG":1.37339,"PCHG":12.27897,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-20 15:15:16","ADY":94,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-145","SUBJID":"id-145","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.20279,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-17 15:15:16","TRT01SDTM":"2020-01-17 15:15:16","AP01SDTM":"2020-01-17 15:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7462,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.30679,"AVALU":"U/L","BASE2":5.68677,"BASE":11.1849,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.62002,"PCHG2":28.48758,"CHG":-3.87812,"PCHG":-34.67278,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-12 15:15:16","ADY":300,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-145","SUBJID":"id-145","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.20279,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-17 15:15:16","TRT01SDTM":"2020-01-17 15:15:16","AP01SDTM":"2020-01-17 15:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8159,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.79717,"AVALU":"U/L","BASE2":5.68677,"BASE":11.1849,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.1104,"PCHG2":283.2964,"CHG":10.61226,"PCHG":94.88023,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-19 15:15:16","ADY":427,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-145","SUBJID":"id-145","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.20279,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-17 15:15:16","TRT01SDTM":"2020-01-17 15:15:16","AP01SDTM":"2020-01-17 15:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1805,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.7322,"AVALU":"U/L","BASE2":5.68677,"BASE":11.1849,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":28.04544,"PCHG2":493.17024,"CHG":22.5473,"PCHG":201.58685,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-02 15:15:16","ADY":655,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-145","SUBJID":"id-145","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.20279,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-17 15:15:16","TRT01SDTM":"2020-01-17 15:15:16","AP01SDTM":"2020-01-17 15:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4354,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.2155,"AVALU":"mg/L","BASE2":8.2155,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-18 15:15:16","ADY":1,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-145","SUBJID":"id-145","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.20279,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-17 15:15:16","TRT01SDTM":"2020-01-17 15:15:16","AP01SDTM":"2020-01-17 15:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7582,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.34734,"AVALU":"mg/L","BASE2":8.2155,"BASE":8.34734,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.13184,"PCHG2":1.60477,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-10 15:15:16","ADY":84,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-145","SUBJID":"id-145","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.20279,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-17 15:15:16","TRT01SDTM":"2020-01-17 15:15:16","AP01SDTM":"2020-01-17 15:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2997,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.72795,"AVALU":"mg/L","BASE2":8.2155,"BASE":8.34734,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.51245,"PCHG2":6.23763,"CHG":0.38061,"PCHG":4.55969,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-13 15:15:16","ADY":87,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-145","SUBJID":"id-145","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.20279,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-17 15:15:16","TRT01SDTM":"2020-01-17 15:15:16","AP01SDTM":"2020-01-17 15:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1286,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.25411,"AVALU":"mg/L","BASE2":8.2155,"BASE":8.34734,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.03861,"PCHG2":12.64212,"CHG":0.90677,"PCHG":10.86303,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-20 15:15:16","ADY":94,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-145","SUBJID":"id-145","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.20279,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-17 15:15:16","TRT01SDTM":"2020-01-17 15:15:16","AP01SDTM":"2020-01-17 15:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4889,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.83936,"AVALU":"mg/L","BASE2":8.2155,"BASE":8.34734,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.62386,"PCHG2":19.76583,"CHG":1.49202,"PCHG":17.87422,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-12 15:15:16","ADY":300,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-145","SUBJID":"id-145","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.20279,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-17 15:15:16","TRT01SDTM":"2020-01-17 15:15:16","AP01SDTM":"2020-01-17 15:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1417,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.86355,"AVALU":"mg/L","BASE2":8.2155,"BASE":8.34734,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.35195,"PCHG2":-4.28395,"CHG":-0.48379,"PCHG":-5.79571,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-03-19 15:15:16","ADY":427,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-145","SUBJID":"id-145","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.20279,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-17 15:15:16","TRT01SDTM":"2020-01-17 15:15:16","AP01SDTM":"2020-01-17 15:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":400,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.06738,"AVALU":"mg/L","BASE2":8.2155,"BASE":8.34734,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.85188,"PCHG2":34.71343,"CHG":2.72004,"PCHG":32.58574,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-11-02 15:15:16","ADY":655,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-145","SUBJID":"id-145","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.20279,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-17 15:15:16","TRT01SDTM":"2020-01-17 15:15:16","AP01SDTM":"2020-01-17 15:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8270,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87216,"AVALU":"g/L","BASE2":2.87216,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-18 15:15:16","ADY":1,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-145","SUBJID":"id-145","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.20279,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-17 15:15:16","TRT01SDTM":"2020-01-17 15:15:16","AP01SDTM":"2020-01-17 15:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1484,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76188,"AVALU":"g/L","BASE2":2.87216,"BASE":2.76188,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.11027,"PCHG2":-3.83941,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-10 15:15:16","ADY":84,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-145","SUBJID":"id-145","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.20279,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-17 15:15:16","TRT01SDTM":"2020-01-17 15:15:16","AP01SDTM":"2020-01-17 15:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3455,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90802,"AVALU":"g/L","BASE2":2.87216,"BASE":2.76188,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03587,"PCHG2":1.24873,"CHG":0.14614,"PCHG":5.2913,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-13 15:15:16","ADY":87,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-145","SUBJID":"id-145","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.20279,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-17 15:15:16","TRT01SDTM":"2020-01-17 15:15:16","AP01SDTM":"2020-01-17 15:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3091,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91814,"AVALU":"g/L","BASE2":2.87216,"BASE":2.76188,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04599,"PCHG2":1.60118,"CHG":0.15626,"PCHG":5.65782,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-20 15:15:16","ADY":94,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-145","SUBJID":"id-145","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.20279,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-17 15:15:16","TRT01SDTM":"2020-01-17 15:15:16","AP01SDTM":"2020-01-17 15:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5916,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93364,"AVALU":"g/L","BASE2":2.87216,"BASE":2.76188,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06148,"PCHG2":2.14068,"CHG":0.17176,"PCHG":6.21887,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-12 15:15:16","ADY":300,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-145","SUBJID":"id-145","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.20279,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-17 15:15:16","TRT01SDTM":"2020-01-17 15:15:16","AP01SDTM":"2020-01-17 15:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2199,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94092,"AVALU":"g/L","BASE2":2.87216,"BASE":2.76188,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06877,"PCHG2":2.39426,"CHG":0.17904,"PCHG":6.48257,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-19 15:15:16","ADY":427,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-145","SUBJID":"id-145","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":8.20279,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-17","TRTSDTM":"2020-01-17 15:15:16","TRT01SDTM":"2020-01-17 15:15:16","AP01SDTM":"2020-01-17 15:15:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7650,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86861,"AVALU":"g/L","BASE2":2.87216,"BASE":2.76188,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00354,"PCHG2":-0.12334,"CHG":0.10673,"PCHG":3.86445,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-02 15:15:16","ADY":655,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-187","SUBJID":"id-187","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.3773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-24 02:15:24","TRT01SDTM":"2019-12-24 02:15:24","AP01SDTM":"2019-12-24 02:15:24","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6110,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.78733,"AVALU":"U/L","BASE2":11.78733,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-27 02:15:24","ADY":34,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-187","SUBJID":"id-187","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.3773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-24 02:15:24","TRT01SDTM":"2019-12-24 02:15:24","AP01SDTM":"2019-12-24 02:15:24","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":384,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.70585,"AVALU":"U/L","BASE2":11.78733,"BASE":9.70585,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.08148,"PCHG2":-17.65862,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-10 02:15:24","ADY":77,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-187","SUBJID":"id-187","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.3773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-24 02:15:24","TRT01SDTM":"2019-12-24 02:15:24","AP01SDTM":"2019-12-24 02:15:24","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3659,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.66685,"AVALU":"U/L","BASE2":11.78733,"BASE":9.70585,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.87952,"PCHG2":92.29837,"CHG":12.961,"PCHG":133.53796,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-03 02:15:24","ADY":162,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-187","SUBJID":"id-187","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.3773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-24 02:15:24","TRT01SDTM":"2019-12-24 02:15:24","AP01SDTM":"2019-12-24 02:15:24","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1713,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.52804,"AVALU":"U/L","BASE2":11.78733,"BASE":9.70585,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.25929,"PCHG2":-2.19973,"CHG":1.82219,"PCHG":18.77415,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-02 02:15:24","ADY":253,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-187","SUBJID":"id-187","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.3773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-24 02:15:24","TRT01SDTM":"2019-12-24 02:15:24","AP01SDTM":"2019-12-24 02:15:24","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7797,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.69729,"AVALU":"U/L","BASE2":11.78733,"BASE":9.70585,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09004,"PCHG2":-0.76391,"CHG":1.99144,"PCHG":20.51789,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-14 02:15:24","ADY":356,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-187","SUBJID":"id-187","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.3773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-24 02:15:24","TRT01SDTM":"2019-12-24 02:15:24","AP01SDTM":"2019-12-24 02:15:24","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1611,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.37547,"AVALU":"U/L","BASE2":11.78733,"BASE":9.70585,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.58814,"PCHG2":140.72853,"CHG":18.66962,"PCHG":192.35427,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-21 02:15:24","ADY":394,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-187","SUBJID":"id-187","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.3773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-24 02:15:24","TRT01SDTM":"2019-12-24 02:15:24","AP01SDTM":"2019-12-24 02:15:24","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3416,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.80419,"AVALU":"U/L","BASE2":11.78733,"BASE":9.70585,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":20.01685,"PCHG2":169.81666,"CHG":22.09834,"PCHG":227.68052,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-28 02:15:24","ADY":705,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-187","SUBJID":"id-187","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.3773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-24 02:15:24","TRT01SDTM":"2019-12-24 02:15:24","AP01SDTM":"2019-12-24 02:15:24","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1294,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.10185,"AVALU":"mg/L","BASE2":9.10185,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-27 02:15:24","ADY":34,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-187","SUBJID":"id-187","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.3773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-24 02:15:24","TRT01SDTM":"2019-12-24 02:15:24","AP01SDTM":"2019-12-24 02:15:24","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2858,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.89303,"AVALU":"mg/L","BASE2":9.10185,"BASE":9.89303,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.79118,"PCHG2":8.69253,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-10 02:15:24","ADY":77,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-187","SUBJID":"id-187","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.3773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-24 02:15:24","TRT01SDTM":"2019-12-24 02:15:24","AP01SDTM":"2019-12-24 02:15:24","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6915,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.10861,"AVALU":"mg/L","BASE2":9.10185,"BASE":9.89303,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.00677,"PCHG2":11.06114,"CHG":0.21559,"PCHG":2.17919,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-06-03 02:15:24","ADY":162,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-187","SUBJID":"id-187","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.3773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-24 02:15:24","TRT01SDTM":"2019-12-24 02:15:24","AP01SDTM":"2019-12-24 02:15:24","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5706,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.47939,"AVALU":"mg/L","BASE2":9.10185,"BASE":9.89303,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.37755,"PCHG2":4.14804,"CHG":-0.41363,"PCHG":-4.18105,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-02 02:15:24","ADY":253,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-187","SUBJID":"id-187","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.3773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-24 02:15:24","TRT01SDTM":"2019-12-24 02:15:24","AP01SDTM":"2019-12-24 02:15:24","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8245,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.2218,"AVALU":"mg/L","BASE2":9.10185,"BASE":9.89303,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.11996,"PCHG2":23.29152,"CHG":1.32878,"PCHG":13.43145,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-12-14 02:15:24","ADY":356,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-187","SUBJID":"id-187","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.3773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-24 02:15:24","TRT01SDTM":"2019-12-24 02:15:24","AP01SDTM":"2019-12-24 02:15:24","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6661,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.98218,"AVALU":"mg/L","BASE2":9.10185,"BASE":9.89303,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.11966,"PCHG2":-12.3015,"CHG":-1.91084,"PCHG":-19.31506,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-01-21 02:15:24","ADY":394,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-187","SUBJID":"id-187","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.3773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-24 02:15:24","TRT01SDTM":"2019-12-24 02:15:24","AP01SDTM":"2019-12-24 02:15:24","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2844,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.29415,"AVALU":"mg/L","BASE2":9.10185,"BASE":9.89303,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.8077,"PCHG2":-19.86078,"CHG":-2.59888,"PCHG":-26.26979,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-11-28 02:15:24","ADY":705,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-187","SUBJID":"id-187","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.3773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-24 02:15:24","TRT01SDTM":"2019-12-24 02:15:24","AP01SDTM":"2019-12-24 02:15:24","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4737,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9069,"AVALU":"g/L","BASE2":2.9069,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"2","ADTM":"2020-01-27 02:15:24","ADY":34,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-187","SUBJID":"id-187","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.3773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-24 02:15:24","TRT01SDTM":"2019-12-24 02:15:24","AP01SDTM":"2019-12-24 02:15:24","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1650,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.06349,"AVALU":"g/L","BASE2":2.9069,"BASE":3.06349,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.15659,"PCHG2":5.38686,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2020-03-10 02:15:24","ADY":77,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-187","SUBJID":"id-187","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.3773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-24 02:15:24","TRT01SDTM":"2019-12-24 02:15:24","AP01SDTM":"2019-12-24 02:15:24","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8080,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7887,"AVALU":"g/L","BASE2":2.9069,"BASE":3.06349,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11819,"PCHG2":-4.06601,"CHG":-0.27479,"PCHG":-8.96969,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2020-06-03 02:15:24","ADY":162,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-187","SUBJID":"id-187","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.3773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-24 02:15:24","TRT01SDTM":"2019-12-24 02:15:24","AP01SDTM":"2019-12-24 02:15:24","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1163,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97093,"AVALU":"g/L","BASE2":2.9069,"BASE":3.06349,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06403,"PCHG2":2.20286,"CHG":-0.09256,"PCHG":-3.02125,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2020-09-02 02:15:24","ADY":253,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-187","SUBJID":"id-187","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.3773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-24 02:15:24","TRT01SDTM":"2019-12-24 02:15:24","AP01SDTM":"2019-12-24 02:15:24","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7094,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84654,"AVALU":"g/L","BASE2":2.9069,"BASE":3.06349,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06035,"PCHG2":-2.07624,"CHG":-0.21694,"PCHG":-7.08162,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2020-12-14 02:15:24","ADY":356,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-187","SUBJID":"id-187","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.3773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-24 02:15:24","TRT01SDTM":"2019-12-24 02:15:24","AP01SDTM":"2019-12-24 02:15:24","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":216,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96413,"AVALU":"g/L","BASE2":2.9069,"BASE":3.06349,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05723,"PCHG2":1.96877,"CHG":-0.09936,"PCHG":-3.24337,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-01-21 02:15:24","ADY":394,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-187","SUBJID":"id-187","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.3773,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-21","TRTSDTM":"2019-12-24 02:15:24","TRT01SDTM":"2019-12-24 02:15:24","AP01SDTM":"2019-12-24 02:15:24","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3723,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83859,"AVALU":"g/L","BASE2":2.9069,"BASE":3.06349,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0683,"PCHG2":-2.3497,"CHG":-0.22489,"PCHG":-7.3411,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-11-28 02:15:24","ADY":705,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-210","SUBJID":"id-210","SITEID":"PAK-11","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.6416,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:53:23","TRT01SDTM":"2019-09-25 15:53:23","AP01SDTM":"2019-09-25 15:53:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5752,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.16707,"AVALU":"U/L","BASE2":25.16707,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-01 15:53:23","ADY":67,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-210","SUBJID":"id-210","SITEID":"PAK-11","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.6416,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:53:23","TRT01SDTM":"2019-09-25 15:53:23","AP01SDTM":"2019-09-25 15:53:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7518,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.77589,"AVALU":"U/L","BASE2":25.16707,"BASE":8.77589,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-16.39118,"PCHG2":-65.12947,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-20 15:53:23","ADY":177,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-210","SUBJID":"id-210","SITEID":"PAK-11","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.6416,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:53:23","TRT01SDTM":"2019-09-25 15:53:23","AP01SDTM":"2019-09-25 15:53:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5831,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.66773,"AVALU":"U/L","BASE2":25.16707,"BASE":8.77589,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-20.49934,"PCHG2":-81.45302,"CHG":-4.10816,"PCHG":-46.8119,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-04-23 15:53:23","ADY":211,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-210","SUBJID":"id-210","SITEID":"PAK-11","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.6416,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:53:23","TRT01SDTM":"2019-09-25 15:53:23","AP01SDTM":"2019-09-25 15:53:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5259,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":37.87969,"AVALU":"U/L","BASE2":25.16707,"BASE":8.77589,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.71261,"PCHG2":50.51287,"CHG":29.10379,"PCHG":331.6334,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-02 15:53:23","ADY":220,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-210","SUBJID":"id-210","SITEID":"PAK-11","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.6416,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:53:23","TRT01SDTM":"2019-09-25 15:53:23","AP01SDTM":"2019-09-25 15:53:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1678,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.54884,"AVALU":"U/L","BASE2":25.16707,"BASE":8.77589,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.61824,"PCHG2":-50.13788,"CHG":3.77294,"PCHG":42.99212,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-26 15:53:23","ADY":244,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-210","SUBJID":"id-210","SITEID":"PAK-11","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.6416,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:53:23","TRT01SDTM":"2019-09-25 15:53:23","AP01SDTM":"2019-09-25 15:53:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8193,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.55436,"AVALU":"U/L","BASE2":25.16707,"BASE":8.77589,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.38729,"PCHG2":9.48575,"CHG":18.77847,"PCHG":213.97784,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-20 15:53:23","ADY":542,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-210","SUBJID":"id-210","SITEID":"PAK-11","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.6416,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:53:23","TRT01SDTM":"2019-09-25 15:53:23","AP01SDTM":"2019-09-25 15:53:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4083,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.66707,"AVALU":"U/L","BASE2":25.16707,"BASE":8.77589,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.5,"PCHG2":-49.66809,"CHG":3.89118,"PCHG":44.33938,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-10 15:53:23","ADY":624,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-210","SUBJID":"id-210","SITEID":"PAK-11","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.6416,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:53:23","TRT01SDTM":"2019-09-25 15:53:23","AP01SDTM":"2019-09-25 15:53:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2216,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.851,"AVALU":"mg/L","BASE2":9.851,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-01 15:53:23","ADY":67,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-210","SUBJID":"id-210","SITEID":"PAK-11","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.6416,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:53:23","TRT01SDTM":"2019-09-25 15:53:23","AP01SDTM":"2019-09-25 15:53:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2432,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.51054,"AVALU":"mg/L","BASE2":9.851,"BASE":8.51054,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.34045,"PCHG2":-13.60727,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-20 15:53:23","ADY":177,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-210","SUBJID":"id-210","SITEID":"PAK-11","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.6416,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:53:23","TRT01SDTM":"2019-09-25 15:53:23","AP01SDTM":"2019-09-25 15:53:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2458,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.42819,"AVALU":"mg/L","BASE2":9.851,"BASE":8.51054,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.42281,"PCHG2":-14.44328,"CHG":-0.08236,"PCHG":-0.96769,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-23 15:53:23","ADY":211,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-210","SUBJID":"id-210","SITEID":"PAK-11","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.6416,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:53:23","TRT01SDTM":"2019-09-25 15:53:23","AP01SDTM":"2019-09-25 15:53:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3623,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.62643,"AVALU":"mg/L","BASE2":9.851,"BASE":8.51054,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.22457,"PCHG2":-22.58216,"CHG":-0.88412,"PCHG":-10.38848,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-05-02 15:53:23","ADY":220,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-210","SUBJID":"id-210","SITEID":"PAK-11","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.6416,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:53:23","TRT01SDTM":"2019-09-25 15:53:23","AP01SDTM":"2019-09-25 15:53:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6241,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.05086,"AVALU":"mg/L","BASE2":9.851,"BASE":8.51054,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.80014,"PCHG2":-18.27364,"CHG":-0.45968,"PCHG":-5.40134,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-26 15:53:23","ADY":244,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-210","SUBJID":"id-210","SITEID":"PAK-11","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.6416,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:53:23","TRT01SDTM":"2019-09-25 15:53:23","AP01SDTM":"2019-09-25 15:53:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":11,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.58616,"AVALU":"mg/L","BASE2":9.851,"BASE":8.51054,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.26484,"PCHG2":-2.68844,"CHG":1.07561,"PCHG":12.63859,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-20 15:53:23","ADY":542,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-210","SUBJID":"id-210","SITEID":"PAK-11","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.6416,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:53:23","TRT01SDTM":"2019-09-25 15:53:23","AP01SDTM":"2019-09-25 15:53:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":266,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.65174,"AVALU":"mg/L","BASE2":9.851,"BASE":8.51054,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.19926,"PCHG2":-12.17397,"CHG":0.14119,"PCHG":1.65905,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-10 15:53:23","ADY":624,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-210","SUBJID":"id-210","SITEID":"PAK-11","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.6416,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:53:23","TRT01SDTM":"2019-09-25 15:53:23","AP01SDTM":"2019-09-25 15:53:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3446,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.12255,"AVALU":"g/L","BASE2":3.12255,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"2","BTOXGR":"0","ADTM":"2019-12-01 15:53:23","ADY":67,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-210","SUBJID":"id-210","SITEID":"PAK-11","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.6416,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:53:23","TRT01SDTM":"2019-09-25 15:53:23","AP01SDTM":"2019-09-25 15:53:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2745,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9081,"AVALU":"g/L","BASE2":3.12255,"BASE":2.9081,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.21445,"PCHG2":-6.86774,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-20 15:53:23","ADY":177,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-210","SUBJID":"id-210","SITEID":"PAK-11","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.6416,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:53:23","TRT01SDTM":"2019-09-25 15:53:23","AP01SDTM":"2019-09-25 15:53:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5981,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94771,"AVALU":"g/L","BASE2":3.12255,"BASE":2.9081,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17484,"PCHG2":-5.59918,"CHG":0.03961,"PCHG":1.3621,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-23 15:53:23","ADY":211,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-210","SUBJID":"id-210","SITEID":"PAK-11","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.6416,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:53:23","TRT01SDTM":"2019-09-25 15:53:23","AP01SDTM":"2019-09-25 15:53:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5894,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99174,"AVALU":"g/L","BASE2":3.12255,"BASE":2.9081,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13081,"PCHG2":-4.18916,"CHG":0.08364,"PCHG":2.8761,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-02 15:53:23","ADY":220,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-210","SUBJID":"id-210","SITEID":"PAK-11","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.6416,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:53:23","TRT01SDTM":"2019-09-25 15:53:23","AP01SDTM":"2019-09-25 15:53:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1798,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88889,"AVALU":"g/L","BASE2":3.12255,"BASE":2.9081,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.23366,"PCHG2":-7.48297,"CHG":-0.01921,"PCHG":-0.6606,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-26 15:53:23","ADY":244,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-210","SUBJID":"id-210","SITEID":"PAK-11","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.6416,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:53:23","TRT01SDTM":"2019-09-25 15:53:23","AP01SDTM":"2019-09-25 15:53:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5767,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80904,"AVALU":"g/L","BASE2":3.12255,"BASE":2.9081,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.3135,"PCHG2":-10.03996,"CHG":-0.09905,"PCHG":-3.40615,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-20 15:53:23","ADY":542,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-210","SUBJID":"id-210","SITEID":"PAK-11","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.6416,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-25","TRTSDTM":"2019-09-25 15:53:23","TRT01SDTM":"2019-09-25 15:53:23","AP01SDTM":"2019-09-25 15:53:23","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":953,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88551,"AVALU":"g/L","BASE2":3.12255,"BASE":2.9081,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.23704,"PCHG2":-7.59115,"CHG":-0.02259,"PCHG":-0.77676,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-10 15:53:23","ADY":624,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-268","SUBJID":"id-268","SITEID":"PAK-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82014,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-21","TRTSDTM":"2019-03-21 23:53:53","TRTEDTM":"2022-03-21 17:53:53","TRT01SDTM":"2019-03-21 23:53:53","TRT01EDTM":"2021-03-21 11:53:53","TRT02SDTM":"2021-03-21 11:53:53","TRT02EDTM":"2022-03-21 17:53:53","AP01SDTM":"2019-03-21 23:53:53","AP01EDTM":"2021-03-21 11:53:53","AP02SDTM":"2021-03-21 11:53:53","AP02EDTM":"2022-03-21 17:53:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-21","EOSDY":1096,"LSTALVDT":"2022-04-02","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8337,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.147,"AVALU":"U/L","BASE2":4.147,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-2","BTOXGR":"0","ADTM":"2019-07-22 23:53:53","ADY":123,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-268","SUBJID":"id-268","SITEID":"PAK-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82014,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-21","TRTSDTM":"2019-03-21 23:53:53","TRTEDTM":"2022-03-21 17:53:53","TRT01SDTM":"2019-03-21 23:53:53","TRT01EDTM":"2021-03-21 11:53:53","TRT02SDTM":"2021-03-21 11:53:53","TRT02EDTM":"2022-03-21 17:53:53","AP01SDTM":"2019-03-21 23:53:53","AP01EDTM":"2021-03-21 11:53:53","AP02SDTM":"2021-03-21 11:53:53","AP02EDTM":"2022-03-21 17:53:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-21","EOSDY":1096,"LSTALVDT":"2022-04-02","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1659,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.60657,"AVALU":"U/L","BASE2":4.147,"BASE":14.60657,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":10.45957,"PCHG2":252.22015,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-28 23:53:53","ADY":129,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-268","SUBJID":"id-268","SITEID":"PAK-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82014,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-21","TRTSDTM":"2019-03-21 23:53:53","TRTEDTM":"2022-03-21 17:53:53","TRT01SDTM":"2019-03-21 23:53:53","TRT01EDTM":"2021-03-21 11:53:53","TRT02SDTM":"2021-03-21 11:53:53","TRT02EDTM":"2022-03-21 17:53:53","AP01SDTM":"2019-03-21 23:53:53","AP01EDTM":"2021-03-21 11:53:53","AP02SDTM":"2021-03-21 11:53:53","AP02EDTM":"2022-03-21 17:53:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-21","EOSDY":1096,"LSTALVDT":"2022-04-02","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4229,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.77151,"AVALU":"U/L","BASE2":4.147,"BASE":14.60657,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.62451,"PCHG2":280.31146,"CHG":1.16495,"PCHG":7.9755,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-08 23:53:53","ADY":324,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-268","SUBJID":"id-268","SITEID":"PAK-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82014,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-21","TRTSDTM":"2019-03-21 23:53:53","TRTEDTM":"2022-03-21 17:53:53","TRT01SDTM":"2019-03-21 23:53:53","TRT01EDTM":"2021-03-21 11:53:53","TRT02SDTM":"2021-03-21 11:53:53","TRT02EDTM":"2022-03-21 17:53:53","AP01SDTM":"2019-03-21 23:53:53","AP01EDTM":"2021-03-21 11:53:53","AP02SDTM":"2021-03-21 11:53:53","AP02EDTM":"2022-03-21 17:53:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-21","EOSDY":1096,"LSTALVDT":"2022-04-02","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4201,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.23964,"AVALU":"U/L","BASE2":4.147,"BASE":14.60657,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.09264,"PCHG2":50.46162,"CHG":-8.36692,"PCHG":-57.28194,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-01-13 23:53:53","ADY":664,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-268","SUBJID":"id-268","SITEID":"PAK-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82014,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-21","TRTSDTM":"2019-03-21 23:53:53","TRTEDTM":"2022-03-21 17:53:53","TRT01SDTM":"2019-03-21 23:53:53","TRT01EDTM":"2021-03-21 11:53:53","TRT02SDTM":"2021-03-21 11:53:53","TRT02EDTM":"2022-03-21 17:53:53","AP01SDTM":"2019-03-21 23:53:53","AP01EDTM":"2021-03-21 11:53:53","AP02SDTM":"2021-03-21 11:53:53","AP02EDTM":"2022-03-21 17:53:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-21","EOSDY":1096,"LSTALVDT":"2022-04-02","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3627,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.18655,"AVALU":"U/L","BASE2":4.147,"BASE":14.60657,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":29.03955,"PCHG2":700.25463,"CHG":18.57998,"PCHG":127.20297,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-22 23:53:53","ADY":763,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-268","SUBJID":"id-268","SITEID":"PAK-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82014,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-21","TRTSDTM":"2019-03-21 23:53:53","TRTEDTM":"2022-03-21 17:53:53","TRT01SDTM":"2019-03-21 23:53:53","TRT01EDTM":"2021-03-21 11:53:53","TRT02SDTM":"2021-03-21 11:53:53","TRT02EDTM":"2022-03-21 17:53:53","AP01SDTM":"2019-03-21 23:53:53","AP01EDTM":"2021-03-21 11:53:53","AP02SDTM":"2021-03-21 11:53:53","AP02EDTM":"2022-03-21 17:53:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-21","EOSDY":1096,"LSTALVDT":"2022-04-02","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":780,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.64527,"AVALU":"U/L","BASE2":4.147,"BASE":14.60657,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.49827,"PCHG2":204.92588,"CHG":-1.96129,"PCHG":-13.42747,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-06 23:53:53","ADY":991,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-268","SUBJID":"id-268","SITEID":"PAK-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82014,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-21","TRTSDTM":"2019-03-21 23:53:53","TRTEDTM":"2022-03-21 17:53:53","TRT01SDTM":"2019-03-21 23:53:53","TRT01EDTM":"2021-03-21 11:53:53","TRT02SDTM":"2021-03-21 11:53:53","TRT02EDTM":"2022-03-21 17:53:53","AP01SDTM":"2019-03-21 23:53:53","AP01EDTM":"2021-03-21 11:53:53","AP02SDTM":"2021-03-21 11:53:53","AP02EDTM":"2022-03-21 17:53:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-21","EOSDY":1096,"LSTALVDT":"2022-04-02","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3918,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.71412,"AVALU":"U/L","BASE2":4.147,"BASE":14.60657,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.56712,"PCHG2":278.9275,"CHG":1.10755,"PCHG":7.58257,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-16 23:53:53","ADY":1063,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-268","SUBJID":"id-268","SITEID":"PAK-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82014,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-21","TRTSDTM":"2019-03-21 23:53:53","TRTEDTM":"2022-03-21 17:53:53","TRT01SDTM":"2019-03-21 23:53:53","TRT01EDTM":"2021-03-21 11:53:53","TRT02SDTM":"2021-03-21 11:53:53","TRT02EDTM":"2022-03-21 17:53:53","AP01SDTM":"2019-03-21 23:53:53","AP01EDTM":"2021-03-21 11:53:53","AP02SDTM":"2021-03-21 11:53:53","AP02EDTM":"2022-03-21 17:53:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-21","EOSDY":1096,"LSTALVDT":"2022-04-02","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3780,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.04292,"AVALU":"mg/L","BASE2":10.04292,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"","ATOXGR":"3","BTOXGR":"-3","ADTM":"2019-07-22 23:53:53","ADY":123,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-268","SUBJID":"id-268","SITEID":"PAK-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82014,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-21","TRTSDTM":"2019-03-21 23:53:53","TRTEDTM":"2022-03-21 17:53:53","TRT01SDTM":"2019-03-21 23:53:53","TRT01EDTM":"2021-03-21 11:53:53","TRT02SDTM":"2021-03-21 11:53:53","TRT02EDTM":"2022-03-21 17:53:53","AP01SDTM":"2019-03-21 23:53:53","AP01EDTM":"2021-03-21 11:53:53","AP02SDTM":"2021-03-21 11:53:53","AP02EDTM":"2022-03-21 17:53:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-21","EOSDY":1096,"LSTALVDT":"2022-04-02","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4520,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.81152,"AVALU":"mg/L","BASE2":10.04292,"BASE":7.81152,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.23139,"PCHG2":-22.21859,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2019-07-28 23:53:53","ADY":129,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-268","SUBJID":"id-268","SITEID":"PAK-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82014,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-21","TRTSDTM":"2019-03-21 23:53:53","TRTEDTM":"2022-03-21 17:53:53","TRT01SDTM":"2019-03-21 23:53:53","TRT01EDTM":"2021-03-21 11:53:53","TRT02SDTM":"2021-03-21 11:53:53","TRT02EDTM":"2022-03-21 17:53:53","AP01SDTM":"2019-03-21 23:53:53","AP01EDTM":"2021-03-21 11:53:53","AP02SDTM":"2021-03-21 11:53:53","AP02EDTM":"2022-03-21 17:53:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-21","EOSDY":1096,"LSTALVDT":"2022-04-02","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4650,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.0365,"AVALU":"mg/L","BASE2":10.04292,"BASE":7.81152,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.00641,"PCHG2":-19.97841,"CHG":0.22498,"PCHG":2.8801,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2020-02-08 23:53:53","ADY":324,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-268","SUBJID":"id-268","SITEID":"PAK-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82014,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-21","TRTSDTM":"2019-03-21 23:53:53","TRTEDTM":"2022-03-21 17:53:53","TRT01SDTM":"2019-03-21 23:53:53","TRT01EDTM":"2021-03-21 11:53:53","TRT02SDTM":"2021-03-21 11:53:53","TRT02EDTM":"2022-03-21 17:53:53","AP01SDTM":"2019-03-21 23:53:53","AP01EDTM":"2021-03-21 11:53:53","AP02SDTM":"2021-03-21 11:53:53","AP02EDTM":"2022-03-21 17:53:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-21","EOSDY":1096,"LSTALVDT":"2022-04-02","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1743,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.1228,"AVALU":"mg/L","BASE2":10.04292,"BASE":7.81152,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.92011,"PCHG2":-29.07635,"CHG":-0.68872,"PCHG":-8.8167,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-3","ADTM":"2021-01-13 23:53:53","ADY":664,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-268","SUBJID":"id-268","SITEID":"PAK-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82014,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-21","TRTSDTM":"2019-03-21 23:53:53","TRTEDTM":"2022-03-21 17:53:53","TRT01SDTM":"2019-03-21 23:53:53","TRT01EDTM":"2021-03-21 11:53:53","TRT02SDTM":"2021-03-21 11:53:53","TRT02EDTM":"2022-03-21 17:53:53","AP01SDTM":"2019-03-21 23:53:53","AP01EDTM":"2021-03-21 11:53:53","AP02SDTM":"2021-03-21 11:53:53","AP02EDTM":"2022-03-21 17:53:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-21","EOSDY":1096,"LSTALVDT":"2022-04-02","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1145,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.66971,"AVALU":"mg/L","BASE2":10.04292,"BASE":7.81152,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.3732,"PCHG2":-3.71605,"CHG":1.85819,"PCHG":23.78787,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-04-22 23:53:53","ADY":763,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-268","SUBJID":"id-268","SITEID":"PAK-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82014,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-21","TRTSDTM":"2019-03-21 23:53:53","TRTEDTM":"2022-03-21 17:53:53","TRT01SDTM":"2019-03-21 23:53:53","TRT01EDTM":"2021-03-21 11:53:53","TRT02SDTM":"2021-03-21 11:53:53","TRT02EDTM":"2022-03-21 17:53:53","AP01SDTM":"2019-03-21 23:53:53","AP01EDTM":"2021-03-21 11:53:53","AP02SDTM":"2021-03-21 11:53:53","AP02EDTM":"2022-03-21 17:53:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-21","EOSDY":1096,"LSTALVDT":"2022-04-02","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1853,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.3947,"AVALU":"mg/L","BASE2":10.04292,"BASE":7.81152,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.64821,"PCHG2":-16.41172,"CHG":0.58318,"PCHG":7.46563,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-12-06 23:53:53","ADY":991,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-268","SUBJID":"id-268","SITEID":"PAK-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82014,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-21","TRTSDTM":"2019-03-21 23:53:53","TRTEDTM":"2022-03-21 17:53:53","TRT01SDTM":"2019-03-21 23:53:53","TRT01EDTM":"2021-03-21 11:53:53","TRT02SDTM":"2021-03-21 11:53:53","TRT02EDTM":"2022-03-21 17:53:53","AP01SDTM":"2019-03-21 23:53:53","AP01EDTM":"2021-03-21 11:53:53","AP02SDTM":"2021-03-21 11:53:53","AP02EDTM":"2022-03-21 17:53:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-21","EOSDY":1096,"LSTALVDT":"2022-04-02","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2996,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.10431,"AVALU":"mg/L","BASE2":10.04292,"BASE":7.81152,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.93861,"PCHG2":-29.26051,"CHG":-0.70721,"PCHG":-9.05348,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2022-02-16 23:53:53","ADY":1063,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-268","SUBJID":"id-268","SITEID":"PAK-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82014,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-21","TRTSDTM":"2019-03-21 23:53:53","TRTEDTM":"2022-03-21 17:53:53","TRT01SDTM":"2019-03-21 23:53:53","TRT01EDTM":"2021-03-21 11:53:53","TRT02SDTM":"2021-03-21 11:53:53","TRT02EDTM":"2022-03-21 17:53:53","AP01SDTM":"2019-03-21 23:53:53","AP01EDTM":"2021-03-21 11:53:53","AP02SDTM":"2021-03-21 11:53:53","AP02EDTM":"2022-03-21 17:53:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-21","EOSDY":1096,"LSTALVDT":"2022-04-02","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5996,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95824,"AVALU":"g/L","BASE2":2.95824,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-22 23:53:53","ADY":123,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-268","SUBJID":"id-268","SITEID":"PAK-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82014,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-21","TRTSDTM":"2019-03-21 23:53:53","TRTEDTM":"2022-03-21 17:53:53","TRT01SDTM":"2019-03-21 23:53:53","TRT01EDTM":"2021-03-21 11:53:53","TRT02SDTM":"2021-03-21 11:53:53","TRT02EDTM":"2022-03-21 17:53:53","AP01SDTM":"2019-03-21 23:53:53","AP01EDTM":"2021-03-21 11:53:53","AP02SDTM":"2021-03-21 11:53:53","AP02EDTM":"2022-03-21 17:53:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-21","EOSDY":1096,"LSTALVDT":"2022-04-02","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7604,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79587,"AVALU":"g/L","BASE2":2.95824,"BASE":2.79587,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.16237,"PCHG2":-5.48868,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-28 23:53:53","ADY":129,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-268","SUBJID":"id-268","SITEID":"PAK-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82014,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-21","TRTSDTM":"2019-03-21 23:53:53","TRTEDTM":"2022-03-21 17:53:53","TRT01SDTM":"2019-03-21 23:53:53","TRT01EDTM":"2021-03-21 11:53:53","TRT02SDTM":"2021-03-21 11:53:53","TRT02EDTM":"2022-03-21 17:53:53","AP01SDTM":"2019-03-21 23:53:53","AP01EDTM":"2021-03-21 11:53:53","AP02SDTM":"2021-03-21 11:53:53","AP02EDTM":"2022-03-21 17:53:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-21","EOSDY":1096,"LSTALVDT":"2022-04-02","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3753,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83253,"AVALU":"g/L","BASE2":2.95824,"BASE":2.79587,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12571,"PCHG2":-4.24939,"CHG":0.03666,"PCHG":1.31126,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-08 23:53:53","ADY":324,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-268","SUBJID":"id-268","SITEID":"PAK-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82014,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-21","TRTSDTM":"2019-03-21 23:53:53","TRTEDTM":"2022-03-21 17:53:53","TRT01SDTM":"2019-03-21 23:53:53","TRT01EDTM":"2021-03-21 11:53:53","TRT02SDTM":"2021-03-21 11:53:53","TRT02EDTM":"2022-03-21 17:53:53","AP01SDTM":"2019-03-21 23:53:53","AP01EDTM":"2021-03-21 11:53:53","AP02SDTM":"2021-03-21 11:53:53","AP02EDTM":"2022-03-21 17:53:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-21","EOSDY":1096,"LSTALVDT":"2022-04-02","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7881,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87086,"AVALU":"g/L","BASE2":2.95824,"BASE":2.79587,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08738,"PCHG2":-2.95379,"CHG":0.07499,"PCHG":2.6821,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-13 23:53:53","ADY":664,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-268","SUBJID":"id-268","SITEID":"PAK-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82014,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-21","TRTSDTM":"2019-03-21 23:53:53","TRTEDTM":"2022-03-21 17:53:53","TRT01SDTM":"2019-03-21 23:53:53","TRT01EDTM":"2021-03-21 11:53:53","TRT02SDTM":"2021-03-21 11:53:53","TRT02EDTM":"2022-03-21 17:53:53","AP01SDTM":"2019-03-21 23:53:53","AP01EDTM":"2021-03-21 11:53:53","AP02SDTM":"2021-03-21 11:53:53","AP02EDTM":"2022-03-21 17:53:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-21","EOSDY":1096,"LSTALVDT":"2022-04-02","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5655,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85083,"AVALU":"g/L","BASE2":2.95824,"BASE":2.79587,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10741,"PCHG2":-3.63096,"CHG":0.05496,"PCHG":1.96561,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-22 23:53:53","ADY":763,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-268","SUBJID":"id-268","SITEID":"PAK-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82014,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-21","TRTSDTM":"2019-03-21 23:53:53","TRTEDTM":"2022-03-21 17:53:53","TRT01SDTM":"2019-03-21 23:53:53","TRT01EDTM":"2021-03-21 11:53:53","TRT02SDTM":"2021-03-21 11:53:53","TRT02EDTM":"2022-03-21 17:53:53","AP01SDTM":"2019-03-21 23:53:53","AP01EDTM":"2021-03-21 11:53:53","AP02SDTM":"2021-03-21 11:53:53","AP02EDTM":"2022-03-21 17:53:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-21","EOSDY":1096,"LSTALVDT":"2022-04-02","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1282,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8003,"AVALU":"g/L","BASE2":2.95824,"BASE":2.79587,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15794,"PCHG2":-5.33902,"CHG":0.00443,"PCHG":0.15834,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-06 23:53:53","ADY":991,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-268","SUBJID":"id-268","SITEID":"PAK-11","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":2.82014,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-21","TRTSDTM":"2019-03-21 23:53:53","TRTEDTM":"2022-03-21 17:53:53","TRT01SDTM":"2019-03-21 23:53:53","TRT01EDTM":"2021-03-21 11:53:53","TRT02SDTM":"2021-03-21 11:53:53","TRT02EDTM":"2022-03-21 17:53:53","AP01SDTM":"2019-03-21 23:53:53","AP01EDTM":"2021-03-21 11:53:53","AP02SDTM":"2021-03-21 11:53:53","AP02EDTM":"2022-03-21 17:53:53","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-21","EOSDY":1096,"LSTALVDT":"2022-04-02","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2548,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05257,"AVALU":"g/L","BASE2":2.95824,"BASE":2.79587,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09433,"PCHG2":3.18868,"CHG":0.2567,"PCHG":9.18129,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-02-16 23:53:53","ADY":1063,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-330","SUBJID":"id-330","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.69531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-15 09:04:51","TRT01SDTM":"2020-01-15 09:04:51","AP01SDTM":"2020-01-15 09:04:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2835,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.27392,"AVALU":"U/L","BASE2":28.27392,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-11 09:04:51","ADY":56,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-330","SUBJID":"id-330","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.69531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-15 09:04:51","TRT01SDTM":"2020-01-15 09:04:51","AP01SDTM":"2020-01-15 09:04:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8333,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.32925,"AVALU":"U/L","BASE2":28.27392,"BASE":27.32925,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.94467,"PCHG2":-3.34115,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-19 09:04:51","ADY":64,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-330","SUBJID":"id-330","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.69531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-15 09:04:51","TRT01SDTM":"2020-01-15 09:04:51","AP01SDTM":"2020-01-15 09:04:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7305,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.87752,"AVALU":"U/L","BASE2":28.27392,"BASE":27.32925,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.3964,"PCHG2":-15.54932,"CHG":-3.45173,"PCHG":-12.63016,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-03 09:04:51","ADY":79,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-330","SUBJID":"id-330","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.69531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-15 09:04:51","TRT01SDTM":"2020-01-15 09:04:51","AP01SDTM":"2020-01-15 09:04:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7697,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.40257,"AVALU":"U/L","BASE2":28.27392,"BASE":27.32925,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.87136,"PCHG2":-27.83964,"CHG":-6.92668,"PCHG":-25.34531,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-14 09:04:51","ADY":181,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-330","SUBJID":"id-330","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.69531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-15 09:04:51","TRT01SDTM":"2020-01-15 09:04:51","AP01SDTM":"2020-01-15 09:04:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":315,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.52709,"AVALU":"U/L","BASE2":28.27392,"BASE":27.32925,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.25317,"PCHG2":7.96908,"CHG":3.19784,"PCHG":11.70118,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-02 09:04:51","ADY":200,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-330","SUBJID":"id-330","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.69531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-15 09:04:51","TRT01SDTM":"2020-01-15 09:04:51","AP01SDTM":"2020-01-15 09:04:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6294,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.97312,"AVALU":"U/L","BASE2":28.27392,"BASE":27.32925,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.30081,"PCHG2":-11.67439,"CHG":-2.35614,"PCHG":-8.62129,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-09 09:04:51","ADY":299,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-330","SUBJID":"id-330","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.69531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-15 09:04:51","TRT01SDTM":"2020-01-15 09:04:51","AP01SDTM":"2020-01-15 09:04:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5324,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.80785,"AVALU":"U/L","BASE2":28.27392,"BASE":27.32925,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.46607,"PCHG2":-15.79573,"CHG":-3.5214,"PCHG":-12.88509,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-23 09:04:51","ADY":433,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-330","SUBJID":"id-330","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.69531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-15 09:04:51","TRT01SDTM":"2020-01-15 09:04:51","AP01SDTM":"2020-01-15 09:04:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2162,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.90403,"AVALU":"mg/L","BASE2":8.90403,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-11 09:04:51","ADY":56,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-330","SUBJID":"id-330","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.69531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-15 09:04:51","TRT01SDTM":"2020-01-15 09:04:51","AP01SDTM":"2020-01-15 09:04:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6556,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.28742,"AVALU":"mg/L","BASE2":8.90403,"BASE":9.28742,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.38339,"PCHG2":4.30576,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-19 09:04:51","ADY":64,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-330","SUBJID":"id-330","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.69531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-15 09:04:51","TRT01SDTM":"2020-01-15 09:04:51","AP01SDTM":"2020-01-15 09:04:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4981,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.60409,"AVALU":"mg/L","BASE2":8.90403,"BASE":9.28742,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.70005,"PCHG2":7.8622,"CHG":0.31667,"PCHG":3.40963,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-03 09:04:51","ADY":79,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-330","SUBJID":"id-330","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.69531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-15 09:04:51","TRT01SDTM":"2020-01-15 09:04:51","AP01SDTM":"2020-01-15 09:04:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2301,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.72788,"AVALU":"mg/L","BASE2":8.90403,"BASE":9.28742,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.17615,"PCHG2":-13.20919,"CHG":-1.55954,"PCHG":-16.79193,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-07-14 09:04:51","ADY":181,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-330","SUBJID":"id-330","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.69531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-15 09:04:51","TRT01SDTM":"2020-01-15 09:04:51","AP01SDTM":"2020-01-15 09:04:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1246,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.55706,"AVALU":"mg/L","BASE2":8.90403,"BASE":9.28742,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.34698,"PCHG2":-15.1277,"CHG":-1.73036,"PCHG":-18.63125,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-08-02 09:04:51","ADY":200,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-330","SUBJID":"id-330","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.69531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-15 09:04:51","TRT01SDTM":"2020-01-15 09:04:51","AP01SDTM":"2020-01-15 09:04:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4312,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.17848,"AVALU":"mg/L","BASE2":8.90403,"BASE":9.28742,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.27444,"PCHG2":3.08221,"CHG":-0.10894,"PCHG":-1.17304,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-09 09:04:51","ADY":299,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-330","SUBJID":"id-330","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.69531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-15 09:04:51","TRT01SDTM":"2020-01-15 09:04:51","AP01SDTM":"2020-01-15 09:04:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2645,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.79107,"AVALU":"mg/L","BASE2":8.90403,"BASE":9.28742,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11296,"PCHG2":-1.26867,"CHG":-0.49635,"PCHG":-5.34432,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-23 09:04:51","ADY":433,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-330","SUBJID":"id-330","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.69531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-15 09:04:51","TRT01SDTM":"2020-01-15 09:04:51","AP01SDTM":"2020-01-15 09:04:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5062,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95274,"AVALU":"g/L","BASE2":2.95274,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-11 09:04:51","ADY":56,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-330","SUBJID":"id-330","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.69531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-15 09:04:51","TRT01SDTM":"2020-01-15 09:04:51","AP01SDTM":"2020-01-15 09:04:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":607,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9689,"AVALU":"g/L","BASE2":2.95274,"BASE":2.9689,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.01616,"PCHG2":0.54733,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-19 09:04:51","ADY":64,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-330","SUBJID":"id-330","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.69531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-15 09:04:51","TRT01SDTM":"2020-01-15 09:04:51","AP01SDTM":"2020-01-15 09:04:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4384,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86994,"AVALU":"g/L","BASE2":2.95274,"BASE":2.9689,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0828,"PCHG2":-2.80406,"CHG":-0.09896,"PCHG":-3.33315,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-03 09:04:51","ADY":79,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-330","SUBJID":"id-330","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.69531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-15 09:04:51","TRT01SDTM":"2020-01-15 09:04:51","AP01SDTM":"2020-01-15 09:04:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5863,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91002,"AVALU":"g/L","BASE2":2.95274,"BASE":2.9689,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04271,"PCHG2":-1.44653,"CHG":-0.05887,"PCHG":-1.98301,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-14 09:04:51","ADY":181,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-330","SUBJID":"id-330","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.69531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-15 09:04:51","TRT01SDTM":"2020-01-15 09:04:51","AP01SDTM":"2020-01-15 09:04:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6931,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82717,"AVALU":"g/L","BASE2":2.95274,"BASE":2.9689,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12556,"PCHG2":-4.25241,"CHG":-0.14172,"PCHG":-4.77361,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-02 09:04:51","ADY":200,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-330","SUBJID":"id-330","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.69531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-15 09:04:51","TRT01SDTM":"2020-01-15 09:04:51","AP01SDTM":"2020-01-15 09:04:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7710,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02223,"AVALU":"g/L","BASE2":2.95274,"BASE":2.9689,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06949,"PCHG2":2.35355,"CHG":0.05333,"PCHG":1.79639,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-11-09 09:04:51","ADY":299,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-330","SUBJID":"id-330","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":6.69531,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-15 09:04:51","TRT01SDTM":"2020-01-15 09:04:51","AP01SDTM":"2020-01-15 09:04:51","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2576,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.73886,"AVALU":"g/L","BASE2":2.95274,"BASE":2.9689,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21387,"PCHG2":-7.24319,"CHG":-0.23003,"PCHG":-7.74811,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-23 09:04:51","ADY":433,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-49","SUBJID":"id-49","SITEID":"PAK-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.14573,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-25 10:00:18","TRT01SDTM":"2019-12-25 10:00:18","AP01SDTM":"2019-12-25 10:00:18","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2670,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.15573,"AVALU":"U/L","BASE2":4.15573,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-01-20 10:00:18","ADY":26,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-49","SUBJID":"id-49","SITEID":"PAK-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.14573,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-25 10:00:18","TRT01SDTM":"2019-12-25 10:00:18","AP01SDTM":"2019-12-25 10:00:18","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2684,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.29212,"AVALU":"U/L","BASE2":4.15573,"BASE":20.29212,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":16.13639,"PCHG2":388.29238,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-08 10:00:18","ADY":135,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-49","SUBJID":"id-49","SITEID":"PAK-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.14573,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-25 10:00:18","TRT01SDTM":"2019-12-25 10:00:18","AP01SDTM":"2019-12-25 10:00:18","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1404,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.93577,"AVALU":"U/L","BASE2":4.15573,"BASE":20.29212,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.78004,"PCHG2":66.89659,"CHG":-13.35635,"PCHG":-65.82036,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-09-14 10:00:18","ADY":264,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-49","SUBJID":"id-49","SITEID":"PAK-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.14573,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-25 10:00:18","TRT01SDTM":"2019-12-25 10:00:18","AP01SDTM":"2019-12-25 10:00:18","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7672,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.61006,"AVALU":"U/L","BASE2":4.15573,"BASE":20.29212,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":17.45433,"PCHG2":420.00608,"CHG":1.31794,"PCHG":6.49482,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-26 10:00:18","ADY":276,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-49","SUBJID":"id-49","SITEID":"PAK-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.14573,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-25 10:00:18","TRT01SDTM":"2019-12-25 10:00:18","AP01SDTM":"2019-12-25 10:00:18","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2784,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.23969,"AVALU":"U/L","BASE2":4.15573,"BASE":20.29212,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.08396,"PCHG2":242.65182,"CHG":-6.05243,"PCHG":-29.82651,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-11 10:00:18","ADY":322,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-49","SUBJID":"id-49","SITEID":"PAK-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.14573,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-25 10:00:18","TRT01SDTM":"2019-12-25 10:00:18","AP01SDTM":"2019-12-25 10:00:18","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2298,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.61716,"AVALU":"U/L","BASE2":4.15573,"BASE":20.29212,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.46143,"PCHG2":251.73494,"CHG":-5.67496,"PCHG":-27.96633,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-26 10:00:18","ADY":337,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-49","SUBJID":"id-49","SITEID":"PAK-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.14573,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-25 10:00:18","TRT01SDTM":"2019-12-25 10:00:18","AP01SDTM":"2019-12-25 10:00:18","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5550,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.02004,"AVALU":"U/L","BASE2":4.15573,"BASE":20.29212,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.86431,"PCHG2":357.68205,"CHG":-1.27208,"PCHG":-6.26885,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-14 10:00:18","ADY":476,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-49","SUBJID":"id-49","SITEID":"PAK-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.14573,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-25 10:00:18","TRT01SDTM":"2019-12-25 10:00:18","AP01SDTM":"2019-12-25 10:00:18","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7070,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.13341,"AVALU":"mg/L","BASE2":8.13341,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-20 10:00:18","ADY":26,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-49","SUBJID":"id-49","SITEID":"PAK-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.14573,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-25 10:00:18","TRT01SDTM":"2019-12-25 10:00:18","AP01SDTM":"2019-12-25 10:00:18","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8132,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.56871,"AVALU":"mg/L","BASE2":8.13341,"BASE":8.56871,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.4353,"PCHG2":5.35204,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-08 10:00:18","ADY":135,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-49","SUBJID":"id-49","SITEID":"PAK-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.14573,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-25 10:00:18","TRT01SDTM":"2019-12-25 10:00:18","AP01SDTM":"2019-12-25 10:00:18","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":996,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.87172,"AVALU":"mg/L","BASE2":8.13341,"BASE":8.56871,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.73832,"PCHG2":21.37259,"CHG":1.30302,"PCHG":15.20669,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-14 10:00:18","ADY":264,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-49","SUBJID":"id-49","SITEID":"PAK-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.14573,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-25 10:00:18","TRT01SDTM":"2019-12-25 10:00:18","AP01SDTM":"2019-12-25 10:00:18","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":706,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.68097,"AVALU":"mg/L","BASE2":8.13341,"BASE":8.56871,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.54756,"PCHG2":6.73227,"CHG":0.11226,"PCHG":1.31012,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-26 10:00:18","ADY":276,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-49","SUBJID":"id-49","SITEID":"PAK-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.14573,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-25 10:00:18","TRT01SDTM":"2019-12-25 10:00:18","AP01SDTM":"2019-12-25 10:00:18","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6486,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.98485,"AVALU":"mg/L","BASE2":8.13341,"BASE":8.56871,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.85145,"PCHG2":10.46853,"CHG":0.41615,"PCHG":4.85657,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-11 10:00:18","ADY":322,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-49","SUBJID":"id-49","SITEID":"PAK-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.14573,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-25 10:00:18","TRT01SDTM":"2019-12-25 10:00:18","AP01SDTM":"2019-12-25 10:00:18","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5993,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.1376,"AVALU":"mg/L","BASE2":8.13341,"BASE":8.56871,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0042,"PCHG2":0.0516,"CHG":-0.43111,"PCHG":-5.03116,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-26 10:00:18","ADY":337,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-49","SUBJID":"id-49","SITEID":"PAK-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.14573,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-25 10:00:18","TRT01SDTM":"2019-12-25 10:00:18","AP01SDTM":"2019-12-25 10:00:18","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4810,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.76632,"AVALU":"mg/L","BASE2":8.13341,"BASE":8.56871,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.36709,"PCHG2":-4.51333,"CHG":-0.80239,"PCHG":-9.3642,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-04-14 10:00:18","ADY":476,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-49","SUBJID":"id-49","SITEID":"PAK-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.14573,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-25 10:00:18","TRT01SDTM":"2019-12-25 10:00:18","AP01SDTM":"2019-12-25 10:00:18","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3864,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87097,"AVALU":"g/L","BASE2":2.87097,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-20 10:00:18","ADY":26,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-49","SUBJID":"id-49","SITEID":"PAK-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.14573,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-25 10:00:18","TRT01SDTM":"2019-12-25 10:00:18","AP01SDTM":"2019-12-25 10:00:18","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":231,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87799,"AVALU":"g/L","BASE2":2.87097,"BASE":2.87799,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.00702,"PCHG2":0.24445,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-08 10:00:18","ADY":135,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-49","SUBJID":"id-49","SITEID":"PAK-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.14573,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-25 10:00:18","TRT01SDTM":"2019-12-25 10:00:18","AP01SDTM":"2019-12-25 10:00:18","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":264,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77635,"AVALU":"g/L","BASE2":2.87097,"BASE":2.87799,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09462,"PCHG2":-3.2957,"CHG":-0.10164,"PCHG":-3.53151,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-14 10:00:18","ADY":264,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-49","SUBJID":"id-49","SITEID":"PAK-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.14573,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-25 10:00:18","TRT01SDTM":"2019-12-25 10:00:18","AP01SDTM":"2019-12-25 10:00:18","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4816,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93599,"AVALU":"g/L","BASE2":2.87097,"BASE":2.87799,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06502,"PCHG2":2.26472,"CHG":0.058,"PCHG":2.01535,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-26 10:00:18","ADY":276,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-49","SUBJID":"id-49","SITEID":"PAK-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.14573,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-25 10:00:18","TRT01SDTM":"2019-12-25 10:00:18","AP01SDTM":"2019-12-25 10:00:18","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7743,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00089,"AVALU":"g/L","BASE2":2.87097,"BASE":2.87799,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12992,"PCHG2":4.52538,"CHG":0.1229,"PCHG":4.2705,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-11-11 10:00:18","ADY":322,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-49","SUBJID":"id-49","SITEID":"PAK-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.14573,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-25 10:00:18","TRT01SDTM":"2019-12-25 10:00:18","AP01SDTM":"2019-12-25 10:00:18","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1517,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75308,"AVALU":"g/L","BASE2":2.87097,"BASE":2.87799,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11789,"PCHG2":-4.10626,"CHG":-0.12491,"PCHG":-4.34009,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-26 10:00:18","ADY":337,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-49","SUBJID":"id-49","SITEID":"PAK-11","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.14573,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-24","TRTSDTM":"2019-12-25 10:00:18","TRT01SDTM":"2019-12-25 10:00:18","AP01SDTM":"2019-12-25 10:00:18","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2781,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95147,"AVALU":"g/L","BASE2":2.87097,"BASE":2.87799,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0805,"PCHG2":2.80405,"CHG":0.07349,"PCHG":2.55337,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-14 10:00:18","ADY":476,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-68","SUBJID":"id-68","SITEID":"PAK-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.24086,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-02","TRTSDTM":"2019-06-03 16:33:00","TRTEDTM":"2022-06-03 10:33:00","TRT01SDTM":"2019-06-03 16:33:00","TRT01EDTM":"2021-06-03 04:33:00","TRT02SDTM":"2021-06-03 04:33:00","TRT02EDTM":"2022-06-03 10:33:00","AP01SDTM":"2019-06-03 16:33:00","AP01EDTM":"2021-06-03 04:33:00","AP02SDTM":"2021-06-03 04:33:00","AP02EDTM":"2022-06-03 10:33:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-03","EOSDY":1096,"LSTALVDT":"2022-06-19","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1338,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.98106,"AVALU":"U/L","BASE2":21.98106,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-15 16:33:00","ADY":195,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-68","SUBJID":"id-68","SITEID":"PAK-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.24086,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-02","TRTSDTM":"2019-06-03 16:33:00","TRTEDTM":"2022-06-03 10:33:00","TRT01SDTM":"2019-06-03 16:33:00","TRT01EDTM":"2021-06-03 04:33:00","TRT02SDTM":"2021-06-03 04:33:00","TRT02EDTM":"2022-06-03 10:33:00","AP01SDTM":"2019-06-03 16:33:00","AP01EDTM":"2021-06-03 04:33:00","AP02SDTM":"2021-06-03 04:33:00","AP02EDTM":"2022-06-03 10:33:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-03","EOSDY":1096,"LSTALVDT":"2022-06-19","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4634,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.65266,"AVALU":"U/L","BASE2":21.98106,"BASE":18.65266,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-3.32839,"PCHG2":-15.1421,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-28 16:33:00","ADY":452,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-68","SUBJID":"id-68","SITEID":"PAK-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.24086,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-02","TRTSDTM":"2019-06-03 16:33:00","TRTEDTM":"2022-06-03 10:33:00","TRT01SDTM":"2019-06-03 16:33:00","TRT01EDTM":"2021-06-03 04:33:00","TRT02SDTM":"2021-06-03 04:33:00","TRT02EDTM":"2022-06-03 10:33:00","AP01SDTM":"2019-06-03 16:33:00","AP01EDTM":"2021-06-03 04:33:00","AP02SDTM":"2021-06-03 04:33:00","AP02EDTM":"2022-06-03 10:33:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-03","EOSDY":1096,"LSTALVDT":"2022-06-19","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":61,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.67914,"AVALU":"U/L","BASE2":21.98106,"BASE":18.65266,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.30192,"PCHG2":-60.51536,"CHG":-9.97352,"PCHG":-53.46969,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-04 16:33:00","ADY":459,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-68","SUBJID":"id-68","SITEID":"PAK-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.24086,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-02","TRTSDTM":"2019-06-03 16:33:00","TRTEDTM":"2022-06-03 10:33:00","TRT01SDTM":"2019-06-03 16:33:00","TRT01EDTM":"2021-06-03 04:33:00","TRT02SDTM":"2021-06-03 04:33:00","TRT02EDTM":"2022-06-03 10:33:00","AP01SDTM":"2019-06-03 16:33:00","AP01EDTM":"2021-06-03 04:33:00","AP02SDTM":"2021-06-03 04:33:00","AP02EDTM":"2022-06-03 10:33:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-03","EOSDY":1096,"LSTALVDT":"2022-06-19","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3531,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":44.32844,"AVALU":"U/L","BASE2":21.98106,"BASE":18.65266,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":22.34738,"PCHG2":101.66654,"CHG":25.67578,"PCHG":137.65206,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-19 16:33:00","ADY":869,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-68","SUBJID":"id-68","SITEID":"PAK-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.24086,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-02","TRTSDTM":"2019-06-03 16:33:00","TRTEDTM":"2022-06-03 10:33:00","TRT01SDTM":"2019-06-03 16:33:00","TRT01EDTM":"2021-06-03 04:33:00","TRT02SDTM":"2021-06-03 04:33:00","TRT02EDTM":"2022-06-03 10:33:00","AP01SDTM":"2019-06-03 16:33:00","AP01EDTM":"2021-06-03 04:33:00","AP02SDTM":"2021-06-03 04:33:00","AP02EDTM":"2022-06-03 10:33:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-03","EOSDY":1096,"LSTALVDT":"2022-06-19","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1723,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.57624,"AVALU":"U/L","BASE2":21.98106,"BASE":18.65266,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.40482,"PCHG2":-65.53289,"CHG":-11.07643,"PCHG":-59.38256,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-05 16:33:00","ADY":978,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-68","SUBJID":"id-68","SITEID":"PAK-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.24086,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-02","TRTSDTM":"2019-06-03 16:33:00","TRTEDTM":"2022-06-03 10:33:00","TRT01SDTM":"2019-06-03 16:33:00","TRT01EDTM":"2021-06-03 04:33:00","TRT02SDTM":"2021-06-03 04:33:00","TRT02EDTM":"2022-06-03 10:33:00","AP01SDTM":"2019-06-03 16:33:00","AP01EDTM":"2021-06-03 04:33:00","AP02SDTM":"2021-06-03 04:33:00","AP02EDTM":"2022-06-03 10:33:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-03","EOSDY":1096,"LSTALVDT":"2022-06-19","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6888,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.01565,"AVALU":"U/L","BASE2":21.98106,"BASE":18.65266,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.96541,"PCHG2":-49.88574,"CHG":-7.63702,"PCHG":-40.94331,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-08 16:33:00","ADY":981,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-68","SUBJID":"id-68","SITEID":"PAK-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.24086,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-02","TRTSDTM":"2019-06-03 16:33:00","TRTEDTM":"2022-06-03 10:33:00","TRT01SDTM":"2019-06-03 16:33:00","TRT01EDTM":"2021-06-03 04:33:00","TRT02SDTM":"2021-06-03 04:33:00","TRT02EDTM":"2022-06-03 10:33:00","AP01SDTM":"2019-06-03 16:33:00","AP01EDTM":"2021-06-03 04:33:00","AP02SDTM":"2021-06-03 04:33:00","AP02EDTM":"2022-06-03 10:33:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-03","EOSDY":1096,"LSTALVDT":"2022-06-19","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3253,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.02866,"AVALU":"U/L","BASE2":21.98106,"BASE":18.65266,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.9524,"PCHG2":-31.62905,"CHG":-3.62401,"PCHG":-19.42889,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-25 16:33:00","ADY":1087,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-68","SUBJID":"id-68","SITEID":"PAK-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.24086,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-02","TRTSDTM":"2019-06-03 16:33:00","TRTEDTM":"2022-06-03 10:33:00","TRT01SDTM":"2019-06-03 16:33:00","TRT01EDTM":"2021-06-03 04:33:00","TRT02SDTM":"2021-06-03 04:33:00","TRT02EDTM":"2022-06-03 10:33:00","AP01SDTM":"2019-06-03 16:33:00","AP01EDTM":"2021-06-03 04:33:00","AP02SDTM":"2021-06-03 04:33:00","AP02EDTM":"2022-06-03 10:33:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-03","EOSDY":1096,"LSTALVDT":"2022-06-19","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5140,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.99764,"AVALU":"mg/L","BASE2":8.99764,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-15 16:33:00","ADY":195,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-68","SUBJID":"id-68","SITEID":"PAK-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.24086,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-02","TRTSDTM":"2019-06-03 16:33:00","TRTEDTM":"2022-06-03 10:33:00","TRT01SDTM":"2019-06-03 16:33:00","TRT01EDTM":"2021-06-03 04:33:00","TRT02SDTM":"2021-06-03 04:33:00","TRT02EDTM":"2022-06-03 10:33:00","AP01SDTM":"2019-06-03 16:33:00","AP01EDTM":"2021-06-03 04:33:00","AP02SDTM":"2021-06-03 04:33:00","AP02EDTM":"2022-06-03 10:33:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-03","EOSDY":1096,"LSTALVDT":"2022-06-19","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":433,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.56109,"AVALU":"mg/L","BASE2":8.99764,"BASE":9.56109,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.56345,"PCHG2":6.26216,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-28 16:33:00","ADY":452,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-68","SUBJID":"id-68","SITEID":"PAK-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.24086,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-02","TRTSDTM":"2019-06-03 16:33:00","TRTEDTM":"2022-06-03 10:33:00","TRT01SDTM":"2019-06-03 16:33:00","TRT01EDTM":"2021-06-03 04:33:00","TRT02SDTM":"2021-06-03 04:33:00","TRT02EDTM":"2022-06-03 10:33:00","AP01SDTM":"2019-06-03 16:33:00","AP01EDTM":"2021-06-03 04:33:00","AP02SDTM":"2021-06-03 04:33:00","AP02EDTM":"2022-06-03 10:33:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-03","EOSDY":1096,"LSTALVDT":"2022-06-19","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2461,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.38159,"AVALU":"mg/L","BASE2":8.99764,"BASE":9.56109,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.38395,"PCHG2":4.26721,"CHG":-0.1795,"PCHG":-1.87738,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-04 16:33:00","ADY":459,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-68","SUBJID":"id-68","SITEID":"PAK-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.24086,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-02","TRTSDTM":"2019-06-03 16:33:00","TRTEDTM":"2022-06-03 10:33:00","TRT01SDTM":"2019-06-03 16:33:00","TRT01EDTM":"2021-06-03 04:33:00","TRT02SDTM":"2021-06-03 04:33:00","TRT02EDTM":"2022-06-03 10:33:00","AP01SDTM":"2019-06-03 16:33:00","AP01EDTM":"2021-06-03 04:33:00","AP02SDTM":"2021-06-03 04:33:00","AP02EDTM":"2022-06-03 10:33:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-03","EOSDY":1096,"LSTALVDT":"2022-06-19","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7457,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.2504,"AVALU":"mg/L","BASE2":8.99764,"BASE":9.56109,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.74724,"PCHG2":-8.30485,"CHG":-1.31069,"PCHG":-13.70855,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-19 16:33:00","ADY":869,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-68","SUBJID":"id-68","SITEID":"PAK-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.24086,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-02","TRTSDTM":"2019-06-03 16:33:00","TRTEDTM":"2022-06-03 10:33:00","TRT01SDTM":"2019-06-03 16:33:00","TRT01EDTM":"2021-06-03 04:33:00","TRT02SDTM":"2021-06-03 04:33:00","TRT02EDTM":"2022-06-03 10:33:00","AP01SDTM":"2019-06-03 16:33:00","AP01EDTM":"2021-06-03 04:33:00","AP02SDTM":"2021-06-03 04:33:00","AP02EDTM":"2022-06-03 10:33:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-03","EOSDY":1096,"LSTALVDT":"2022-06-19","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1044,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.14792,"AVALU":"mg/L","BASE2":8.99764,"BASE":9.56109,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.15028,"PCHG2":12.78423,"CHG":0.58683,"PCHG":6.13772,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-02-05 16:33:00","ADY":978,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-68","SUBJID":"id-68","SITEID":"PAK-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.24086,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-02","TRTSDTM":"2019-06-03 16:33:00","TRTEDTM":"2022-06-03 10:33:00","TRT01SDTM":"2019-06-03 16:33:00","TRT01EDTM":"2021-06-03 04:33:00","TRT02SDTM":"2021-06-03 04:33:00","TRT02EDTM":"2022-06-03 10:33:00","AP01SDTM":"2019-06-03 16:33:00","AP01EDTM":"2021-06-03 04:33:00","AP02SDTM":"2021-06-03 04:33:00","AP02EDTM":"2022-06-03 10:33:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-03","EOSDY":1096,"LSTALVDT":"2022-06-19","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5214,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.81098,"AVALU":"mg/L","BASE2":8.99764,"BASE":9.56109,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.18667,"PCHG2":-13.18864,"CHG":-1.75011,"PCHG":-18.30454,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-02-08 16:33:00","ADY":981,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-68","SUBJID":"id-68","SITEID":"PAK-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.24086,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-02","TRTSDTM":"2019-06-03 16:33:00","TRTEDTM":"2022-06-03 10:33:00","TRT01SDTM":"2019-06-03 16:33:00","TRT01EDTM":"2021-06-03 04:33:00","TRT02SDTM":"2021-06-03 04:33:00","TRT02EDTM":"2022-06-03 10:33:00","AP01SDTM":"2019-06-03 16:33:00","AP01EDTM":"2021-06-03 04:33:00","AP02SDTM":"2021-06-03 04:33:00","AP02EDTM":"2022-06-03 10:33:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-03","EOSDY":1096,"LSTALVDT":"2022-06-19","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2705,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.41631,"AVALU":"mg/L","BASE2":8.99764,"BASE":9.56109,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.41867,"PCHG2":15.76715,"CHG":0.85523,"PCHG":8.94485,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-05-25 16:33:00","ADY":1087,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-68","SUBJID":"id-68","SITEID":"PAK-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.24086,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-02","TRTSDTM":"2019-06-03 16:33:00","TRTEDTM":"2022-06-03 10:33:00","TRT01SDTM":"2019-06-03 16:33:00","TRT01EDTM":"2021-06-03 04:33:00","TRT02SDTM":"2021-06-03 04:33:00","TRT02EDTM":"2022-06-03 10:33:00","AP01SDTM":"2019-06-03 16:33:00","AP01EDTM":"2021-06-03 04:33:00","AP02SDTM":"2021-06-03 04:33:00","AP02EDTM":"2022-06-03 10:33:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-03","EOSDY":1096,"LSTALVDT":"2022-06-19","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4393,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97433,"AVALU":"g/L","BASE2":2.97433,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-15 16:33:00","ADY":195,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-68","SUBJID":"id-68","SITEID":"PAK-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.24086,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-02","TRTSDTM":"2019-06-03 16:33:00","TRTEDTM":"2022-06-03 10:33:00","TRT01SDTM":"2019-06-03 16:33:00","TRT01EDTM":"2021-06-03 04:33:00","TRT02SDTM":"2021-06-03 04:33:00","TRT02EDTM":"2022-06-03 10:33:00","AP01SDTM":"2019-06-03 16:33:00","AP01EDTM":"2021-06-03 04:33:00","AP02SDTM":"2021-06-03 04:33:00","AP02EDTM":"2022-06-03 10:33:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-03","EOSDY":1096,"LSTALVDT":"2022-06-19","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1623,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88371,"AVALU":"g/L","BASE2":2.97433,"BASE":2.88371,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.09061,"PCHG2":-3.04654,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-28 16:33:00","ADY":452,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-68","SUBJID":"id-68","SITEID":"PAK-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.24086,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-02","TRTSDTM":"2019-06-03 16:33:00","TRTEDTM":"2022-06-03 10:33:00","TRT01SDTM":"2019-06-03 16:33:00","TRT01EDTM":"2021-06-03 04:33:00","TRT02SDTM":"2021-06-03 04:33:00","TRT02EDTM":"2022-06-03 10:33:00","AP01SDTM":"2019-06-03 16:33:00","AP01EDTM":"2021-06-03 04:33:00","AP02SDTM":"2021-06-03 04:33:00","AP02EDTM":"2022-06-03 10:33:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-03","EOSDY":1096,"LSTALVDT":"2022-06-19","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1112,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94199,"AVALU":"g/L","BASE2":2.97433,"BASE":2.88371,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03233,"PCHG2":-1.08712,"CHG":0.05828,"PCHG":2.02099,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-04 16:33:00","ADY":459,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-68","SUBJID":"id-68","SITEID":"PAK-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.24086,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-02","TRTSDTM":"2019-06-03 16:33:00","TRTEDTM":"2022-06-03 10:33:00","TRT01SDTM":"2019-06-03 16:33:00","TRT01EDTM":"2021-06-03 04:33:00","TRT02SDTM":"2021-06-03 04:33:00","TRT02EDTM":"2022-06-03 10:33:00","AP01SDTM":"2019-06-03 16:33:00","AP01EDTM":"2021-06-03 04:33:00","AP02SDTM":"2021-06-03 04:33:00","AP02EDTM":"2022-06-03 10:33:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-03","EOSDY":1096,"LSTALVDT":"2022-06-19","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6249,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01276,"AVALU":"g/L","BASE2":2.97433,"BASE":2.88371,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03844,"PCHG2":1.2923,"CHG":0.12905,"PCHG":4.47517,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-10-19 16:33:00","ADY":869,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-68","SUBJID":"id-68","SITEID":"PAK-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.24086,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-02","TRTSDTM":"2019-06-03 16:33:00","TRTEDTM":"2022-06-03 10:33:00","TRT01SDTM":"2019-06-03 16:33:00","TRT01EDTM":"2021-06-03 04:33:00","TRT02SDTM":"2021-06-03 04:33:00","TRT02EDTM":"2022-06-03 10:33:00","AP01SDTM":"2019-06-03 16:33:00","AP01EDTM":"2021-06-03 04:33:00","AP02SDTM":"2021-06-03 04:33:00","AP02EDTM":"2022-06-03 10:33:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-03","EOSDY":1096,"LSTALVDT":"2022-06-19","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3760,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76868,"AVALU":"g/L","BASE2":2.97433,"BASE":2.88371,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20565,"PCHG2":-6.91413,"CHG":-0.11503,"PCHG":-3.98913,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-05 16:33:00","ADY":978,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-68","SUBJID":"id-68","SITEID":"PAK-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.24086,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-02","TRTSDTM":"2019-06-03 16:33:00","TRTEDTM":"2022-06-03 10:33:00","TRT01SDTM":"2019-06-03 16:33:00","TRT01EDTM":"2021-06-03 04:33:00","TRT02SDTM":"2021-06-03 04:33:00","TRT02EDTM":"2022-06-03 10:33:00","AP01SDTM":"2019-06-03 16:33:00","AP01EDTM":"2021-06-03 04:33:00","AP02SDTM":"2021-06-03 04:33:00","AP02EDTM":"2022-06-03 10:33:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-03","EOSDY":1096,"LSTALVDT":"2022-06-19","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1657,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96363,"AVALU":"g/L","BASE2":2.97433,"BASE":2.88371,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01069,"PCHG2":-0.35948,"CHG":0.07992,"PCHG":2.77149,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-08 16:33:00","ADY":981,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-68","SUBJID":"id-68","SITEID":"PAK-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S1","BMRKR1":5.24086,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-02","TRTSDTM":"2019-06-03 16:33:00","TRTEDTM":"2022-06-03 10:33:00","TRT01SDTM":"2019-06-03 16:33:00","TRT01EDTM":"2021-06-03 04:33:00","TRT02SDTM":"2021-06-03 04:33:00","TRT02EDTM":"2022-06-03 10:33:00","AP01SDTM":"2019-06-03 16:33:00","AP01EDTM":"2021-06-03 04:33:00","AP02SDTM":"2021-06-03 04:33:00","AP02EDTM":"2022-06-03 10:33:00","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-03","EOSDY":1096,"LSTALVDT":"2022-06-19","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5643,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93841,"AVALU":"g/L","BASE2":2.97433,"BASE":2.88371,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03592,"PCHG2":-1.20763,"CHG":0.0547,"PCHG":1.89669,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-25 16:33:00","ADY":1087,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-82","SUBJID":"id-82","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.98363,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-18 15:55:14","TRTEDTM":"2023-10-19 09:55:14","TRT01SDTM":"2020-10-18 15:55:14","TRT01EDTM":"2022-10-19 03:55:14","TRT02SDTM":"2022-10-19 03:55:14","TRT02EDTM":"2023-10-19 09:55:14","AP01SDTM":"2020-10-18 15:55:14","AP01EDTM":"2022-10-19 03:55:14","AP02SDTM":"2022-10-19 03:55:14","AP02EDTM":"2023-10-19 09:55:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-19","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2591,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.32549,"AVALU":"U/L","BASE2":14.32549,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-10 15:55:14","ADY":23,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-82","SUBJID":"id-82","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.98363,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-18 15:55:14","TRTEDTM":"2023-10-19 09:55:14","TRT01SDTM":"2020-10-18 15:55:14","TRT01EDTM":"2022-10-19 03:55:14","TRT02SDTM":"2022-10-19 03:55:14","TRT02EDTM":"2023-10-19 09:55:14","AP01SDTM":"2020-10-18 15:55:14","AP01EDTM":"2022-10-19 03:55:14","AP02SDTM":"2022-10-19 03:55:14","AP02EDTM":"2023-10-19 09:55:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-19","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7550,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.72257,"AVALU":"U/L","BASE2":14.32549,"BASE":11.72257,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.60292,"PCHG2":-18.16983,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-10 15:55:14","ADY":174,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-82","SUBJID":"id-82","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.98363,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-18 15:55:14","TRTEDTM":"2023-10-19 09:55:14","TRT01SDTM":"2020-10-18 15:55:14","TRT01EDTM":"2022-10-19 03:55:14","TRT02SDTM":"2022-10-19 03:55:14","TRT02EDTM":"2023-10-19 09:55:14","AP01SDTM":"2020-10-18 15:55:14","AP01EDTM":"2022-10-19 03:55:14","AP02SDTM":"2022-10-19 03:55:14","AP02EDTM":"2023-10-19 09:55:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-19","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5369,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.7913,"AVALU":"U/L","BASE2":14.32549,"BASE":11.72257,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":17.4658,"PCHG2":121.92114,"CHG":20.06872,"PCHG":171.19721,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-28 15:55:14","ADY":345,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-82","SUBJID":"id-82","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.98363,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-18 15:55:14","TRTEDTM":"2023-10-19 09:55:14","TRT01SDTM":"2020-10-18 15:55:14","TRT01EDTM":"2022-10-19 03:55:14","TRT02SDTM":"2022-10-19 03:55:14","TRT02EDTM":"2023-10-19 09:55:14","AP01SDTM":"2020-10-18 15:55:14","AP01EDTM":"2022-10-19 03:55:14","AP02SDTM":"2022-10-19 03:55:14","AP02EDTM":"2023-10-19 09:55:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-19","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3958,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.45406,"AVALU":"U/L","BASE2":14.32549,"BASE":11.72257,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.12857,"PCHG2":14.85861,"CHG":4.73149,"PCHG":40.36217,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-11 15:55:14","ADY":358,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-82","SUBJID":"id-82","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.98363,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-18 15:55:14","TRTEDTM":"2023-10-19 09:55:14","TRT01SDTM":"2020-10-18 15:55:14","TRT01EDTM":"2022-10-19 03:55:14","TRT02SDTM":"2022-10-19 03:55:14","TRT02EDTM":"2023-10-19 09:55:14","AP01SDTM":"2020-10-18 15:55:14","AP01EDTM":"2022-10-19 03:55:14","AP02SDTM":"2022-10-19 03:55:14","AP02EDTM":"2023-10-19 09:55:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-19","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6331,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.17242,"AVALU":"U/L","BASE2":14.32549,"BASE":11.72257,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.15307,"PCHG2":-42.9519,"CHG":-3.55015,"PCHG":-30.28476,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-23 15:55:14","ADY":370,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-82","SUBJID":"id-82","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.98363,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-18 15:55:14","TRTEDTM":"2023-10-19 09:55:14","TRT01SDTM":"2020-10-18 15:55:14","TRT01EDTM":"2022-10-19 03:55:14","TRT02SDTM":"2022-10-19 03:55:14","TRT02EDTM":"2023-10-19 09:55:14","AP01SDTM":"2020-10-18 15:55:14","AP01EDTM":"2022-10-19 03:55:14","AP02SDTM":"2022-10-19 03:55:14","AP02EDTM":"2023-10-19 09:55:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-19","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3901,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.26858,"AVALU":"U/L","BASE2":14.32549,"BASE":11.72257,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.05691,"PCHG2":-35.30007,"CHG":-2.45399,"PCHG":-20.9339,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-21 15:55:14","ADY":580,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-82","SUBJID":"id-82","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.98363,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-18 15:55:14","TRTEDTM":"2023-10-19 09:55:14","TRT01SDTM":"2020-10-18 15:55:14","TRT01EDTM":"2022-10-19 03:55:14","TRT02SDTM":"2022-10-19 03:55:14","TRT02EDTM":"2023-10-19 09:55:14","AP01SDTM":"2020-10-18 15:55:14","AP01EDTM":"2022-10-19 03:55:14","AP02SDTM":"2022-10-19 03:55:14","AP02EDTM":"2023-10-19 09:55:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-19","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2426,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.86786,"AVALU":"U/L","BASE2":14.32549,"BASE":11.72257,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.54237,"PCHG2":38.68884,"CHG":8.14529,"PCHG":69.48375,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-21 15:55:14","ADY":611,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-82","SUBJID":"id-82","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.98363,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-18 15:55:14","TRTEDTM":"2023-10-19 09:55:14","TRT01SDTM":"2020-10-18 15:55:14","TRT01EDTM":"2022-10-19 03:55:14","TRT02SDTM":"2022-10-19 03:55:14","TRT02EDTM":"2023-10-19 09:55:14","AP01SDTM":"2020-10-18 15:55:14","AP01EDTM":"2022-10-19 03:55:14","AP02SDTM":"2022-10-19 03:55:14","AP02EDTM":"2023-10-19 09:55:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-19","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2927,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.24098,"AVALU":"mg/L","BASE2":9.24098,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-10 15:55:14","ADY":23,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-82","SUBJID":"id-82","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.98363,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-18 15:55:14","TRTEDTM":"2023-10-19 09:55:14","TRT01SDTM":"2020-10-18 15:55:14","TRT01EDTM":"2022-10-19 03:55:14","TRT02SDTM":"2022-10-19 03:55:14","TRT02EDTM":"2023-10-19 09:55:14","AP01SDTM":"2020-10-18 15:55:14","AP01EDTM":"2022-10-19 03:55:14","AP02SDTM":"2022-10-19 03:55:14","AP02EDTM":"2023-10-19 09:55:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-19","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4934,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.2377,"AVALU":"mg/L","BASE2":9.24098,"BASE":9.2377,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.00327,"PCHG2":-0.03543,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-10 15:55:14","ADY":174,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-82","SUBJID":"id-82","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.98363,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-18 15:55:14","TRTEDTM":"2023-10-19 09:55:14","TRT01SDTM":"2020-10-18 15:55:14","TRT01EDTM":"2022-10-19 03:55:14","TRT02SDTM":"2022-10-19 03:55:14","TRT02EDTM":"2023-10-19 09:55:14","AP01SDTM":"2020-10-18 15:55:14","AP01EDTM":"2022-10-19 03:55:14","AP02SDTM":"2022-10-19 03:55:14","AP02EDTM":"2023-10-19 09:55:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-19","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5961,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.73739,"AVALU":"mg/L","BASE2":9.24098,"BASE":9.2377,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.49642,"PCHG2":5.37191,"CHG":0.49969,"PCHG":5.40925,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-28 15:55:14","ADY":345,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-82","SUBJID":"id-82","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.98363,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-18 15:55:14","TRTEDTM":"2023-10-19 09:55:14","TRT01SDTM":"2020-10-18 15:55:14","TRT01EDTM":"2022-10-19 03:55:14","TRT02SDTM":"2022-10-19 03:55:14","TRT02EDTM":"2023-10-19 09:55:14","AP01SDTM":"2020-10-18 15:55:14","AP01EDTM":"2022-10-19 03:55:14","AP02SDTM":"2022-10-19 03:55:14","AP02EDTM":"2023-10-19 09:55:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-19","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3624,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.62027,"AVALU":"mg/L","BASE2":9.24098,"BASE":9.2377,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.62071,"PCHG2":-6.71692,"CHG":-0.61744,"PCHG":-6.68386,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-11 15:55:14","ADY":358,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-82","SUBJID":"id-82","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.98363,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-18 15:55:14","TRTEDTM":"2023-10-19 09:55:14","TRT01SDTM":"2020-10-18 15:55:14","TRT01EDTM":"2022-10-19 03:55:14","TRT02SDTM":"2022-10-19 03:55:14","TRT02EDTM":"2023-10-19 09:55:14","AP01SDTM":"2020-10-18 15:55:14","AP01EDTM":"2022-10-19 03:55:14","AP02SDTM":"2022-10-19 03:55:14","AP02EDTM":"2023-10-19 09:55:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-19","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1326,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.52278,"AVALU":"mg/L","BASE2":9.24098,"BASE":9.2377,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.71819,"PCHG2":-7.77182,"CHG":-0.71492,"PCHG":-7.73914,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-23 15:55:14","ADY":370,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-82","SUBJID":"id-82","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.98363,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-18 15:55:14","TRTEDTM":"2023-10-19 09:55:14","TRT01SDTM":"2020-10-18 15:55:14","TRT01EDTM":"2022-10-19 03:55:14","TRT02SDTM":"2022-10-19 03:55:14","TRT02EDTM":"2023-10-19 09:55:14","AP01SDTM":"2020-10-18 15:55:14","AP01EDTM":"2022-10-19 03:55:14","AP02SDTM":"2022-10-19 03:55:14","AP02EDTM":"2023-10-19 09:55:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-19","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":253,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.89146,"AVALU":"mg/L","BASE2":9.24098,"BASE":9.2377,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.34952,"PCHG2":-3.78228,"CHG":-0.34625,"PCHG":-3.74818,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-21 15:55:14","ADY":580,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-82","SUBJID":"id-82","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.98363,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-18 15:55:14","TRTEDTM":"2023-10-19 09:55:14","TRT01SDTM":"2020-10-18 15:55:14","TRT01EDTM":"2022-10-19 03:55:14","TRT02SDTM":"2022-10-19 03:55:14","TRT02EDTM":"2023-10-19 09:55:14","AP01SDTM":"2020-10-18 15:55:14","AP01EDTM":"2022-10-19 03:55:14","AP02SDTM":"2022-10-19 03:55:14","AP02EDTM":"2023-10-19 09:55:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-19","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":533,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.25871,"AVALU":"mg/L","BASE2":9.24098,"BASE":9.2377,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.98227,"PCHG2":-10.62949,"CHG":-0.979,"PCHG":-10.59782,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-21 15:55:14","ADY":611,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-82","SUBJID":"id-82","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.98363,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-18 15:55:14","TRTEDTM":"2023-10-19 09:55:14","TRT01SDTM":"2020-10-18 15:55:14","TRT01EDTM":"2022-10-19 03:55:14","TRT02SDTM":"2022-10-19 03:55:14","TRT02EDTM":"2023-10-19 09:55:14","AP01SDTM":"2020-10-18 15:55:14","AP01EDTM":"2022-10-19 03:55:14","AP02SDTM":"2022-10-19 03:55:14","AP02EDTM":"2023-10-19 09:55:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-19","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7265,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89214,"AVALU":"g/L","BASE2":2.89214,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-10 15:55:14","ADY":23,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-82","SUBJID":"id-82","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.98363,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-18 15:55:14","TRTEDTM":"2023-10-19 09:55:14","TRT01SDTM":"2020-10-18 15:55:14","TRT01EDTM":"2022-10-19 03:55:14","TRT02SDTM":"2022-10-19 03:55:14","TRT02EDTM":"2023-10-19 09:55:14","AP01SDTM":"2020-10-18 15:55:14","AP01EDTM":"2022-10-19 03:55:14","AP02SDTM":"2022-10-19 03:55:14","AP02EDTM":"2023-10-19 09:55:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-19","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2460,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74916,"AVALU":"g/L","BASE2":2.89214,"BASE":2.74916,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.14299,"PCHG2":-4.94396,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-10 15:55:14","ADY":174,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-82","SUBJID":"id-82","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.98363,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-18 15:55:14","TRTEDTM":"2023-10-19 09:55:14","TRT01SDTM":"2020-10-18 15:55:14","TRT01EDTM":"2022-10-19 03:55:14","TRT02SDTM":"2022-10-19 03:55:14","TRT02EDTM":"2023-10-19 09:55:14","AP01SDTM":"2020-10-18 15:55:14","AP01EDTM":"2022-10-19 03:55:14","AP02SDTM":"2022-10-19 03:55:14","AP02EDTM":"2023-10-19 09:55:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-19","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5383,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99007,"AVALU":"g/L","BASE2":2.89214,"BASE":2.74916,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09793,"PCHG2":3.38596,"CHG":0.24091,"PCHG":8.76317,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-28 15:55:14","ADY":345,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-82","SUBJID":"id-82","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.98363,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-18 15:55:14","TRTEDTM":"2023-10-19 09:55:14","TRT01SDTM":"2020-10-18 15:55:14","TRT01EDTM":"2022-10-19 03:55:14","TRT02SDTM":"2022-10-19 03:55:14","TRT02EDTM":"2023-10-19 09:55:14","AP01SDTM":"2020-10-18 15:55:14","AP01EDTM":"2022-10-19 03:55:14","AP02SDTM":"2022-10-19 03:55:14","AP02EDTM":"2023-10-19 09:55:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-19","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3666,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95728,"AVALU":"g/L","BASE2":2.89214,"BASE":2.74916,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06514,"PCHG2":2.25217,"CHG":0.20812,"PCHG":7.57041,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-11 15:55:14","ADY":358,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-82","SUBJID":"id-82","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.98363,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-18 15:55:14","TRTEDTM":"2023-10-19 09:55:14","TRT01SDTM":"2020-10-18 15:55:14","TRT01EDTM":"2022-10-19 03:55:14","TRT02SDTM":"2022-10-19 03:55:14","TRT02EDTM":"2023-10-19 09:55:14","AP01SDTM":"2020-10-18 15:55:14","AP01EDTM":"2022-10-19 03:55:14","AP02SDTM":"2022-10-19 03:55:14","AP02EDTM":"2023-10-19 09:55:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-19","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3375,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80696,"AVALU":"g/L","BASE2":2.89214,"BASE":2.74916,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08518,"PCHG2":-2.94538,"CHG":0.0578,"PCHG":2.10252,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-23 15:55:14","ADY":370,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-82","SUBJID":"id-82","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.98363,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-18 15:55:14","TRTEDTM":"2023-10-19 09:55:14","TRT01SDTM":"2020-10-18 15:55:14","TRT01EDTM":"2022-10-19 03:55:14","TRT02SDTM":"2022-10-19 03:55:14","TRT02EDTM":"2023-10-19 09:55:14","AP01SDTM":"2020-10-18 15:55:14","AP01EDTM":"2022-10-19 03:55:14","AP02SDTM":"2022-10-19 03:55:14","AP02EDTM":"2023-10-19 09:55:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-19","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6851,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93685,"AVALU":"g/L","BASE2":2.89214,"BASE":2.74916,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04471,"PCHG2":1.54574,"CHG":0.18769,"PCHG":6.82724,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-21 15:55:14","ADY":580,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-82","SUBJID":"id-82","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.98363,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-16","TRTSDTM":"2020-10-18 15:55:14","TRTEDTM":"2023-10-19 09:55:14","TRT01SDTM":"2020-10-18 15:55:14","TRT01EDTM":"2022-10-19 03:55:14","TRT02SDTM":"2022-10-19 03:55:14","TRT02EDTM":"2023-10-19 09:55:14","AP01SDTM":"2020-10-18 15:55:14","AP01EDTM":"2022-10-19 03:55:14","AP02SDTM":"2022-10-19 03:55:14","AP02EDTM":"2023-10-19 09:55:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-10-19","EOSDY":1096,"LSTALVDT":"2023-10-30","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4612,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82447,"AVALU":"g/L","BASE2":2.89214,"BASE":2.74916,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06768,"PCHG2":-2.34,"CHG":0.07531,"PCHG":2.73939,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-21 15:55:14","ADY":611,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-87","SUBJID":"id-87","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.47621,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-21 00:20:16","TRTEDTM":"2022-07-20 18:20:16","TRT01SDTM":"2019-07-21 00:20:16","TRT01EDTM":"2021-07-20 12:20:16","TRT02SDTM":"2021-07-20 12:20:16","TRT02EDTM":"2022-07-20 18:20:16","AP01SDTM":"2019-07-21 00:20:16","AP01EDTM":"2021-07-20 12:20:16","AP02SDTM":"2021-07-20 12:20:16","AP02EDTM":"2022-07-20 18:20:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4104,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.7551,"AVALU":"U/L","BASE2":22.7551,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-22 00:20:16","ADY":124,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-87","SUBJID":"id-87","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.47621,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-21 00:20:16","TRTEDTM":"2022-07-20 18:20:16","TRT01SDTM":"2019-07-21 00:20:16","TRT01EDTM":"2021-07-20 12:20:16","TRT02SDTM":"2021-07-20 12:20:16","TRT02EDTM":"2022-07-20 18:20:16","AP01SDTM":"2019-07-21 00:20:16","AP01EDTM":"2021-07-20 12:20:16","AP02SDTM":"2021-07-20 12:20:16","AP02EDTM":"2022-07-20 18:20:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3086,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.93866,"AVALU":"U/L","BASE2":22.7551,"BASE":27.93866,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":5.18357,"PCHG2":22.77982,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-14 00:20:16","ADY":146,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-87","SUBJID":"id-87","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.47621,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-21 00:20:16","TRTEDTM":"2022-07-20 18:20:16","TRT01SDTM":"2019-07-21 00:20:16","TRT01EDTM":"2021-07-20 12:20:16","TRT02SDTM":"2021-07-20 12:20:16","TRT02EDTM":"2022-07-20 18:20:16","AP01SDTM":"2019-07-21 00:20:16","AP01EDTM":"2021-07-20 12:20:16","AP02SDTM":"2021-07-20 12:20:16","AP02EDTM":"2022-07-20 18:20:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":350,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.28523,"AVALU":"U/L","BASE2":22.7551,"BASE":27.93866,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.46987,"PCHG2":-24.03798,"CHG":-10.65344,"PCHG":-38.13151,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-19 00:20:16","ADY":273,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-87","SUBJID":"id-87","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.47621,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-21 00:20:16","TRTEDTM":"2022-07-20 18:20:16","TRT01SDTM":"2019-07-21 00:20:16","TRT01EDTM":"2021-07-20 12:20:16","TRT02SDTM":"2021-07-20 12:20:16","TRT02EDTM":"2022-07-20 18:20:16","AP01SDTM":"2019-07-21 00:20:16","AP01EDTM":"2021-07-20 12:20:16","AP02SDTM":"2021-07-20 12:20:16","AP02EDTM":"2022-07-20 18:20:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6132,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.19103,"AVALU":"U/L","BASE2":22.7551,"BASE":27.93866,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.56407,"PCHG2":-55.21431,"CHG":-17.74764,"PCHG":-63.52358,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-02 00:20:16","ADY":562,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-87","SUBJID":"id-87","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.47621,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-21 00:20:16","TRTEDTM":"2022-07-20 18:20:16","TRT01SDTM":"2019-07-21 00:20:16","TRT01EDTM":"2021-07-20 12:20:16","TRT02SDTM":"2021-07-20 12:20:16","TRT02EDTM":"2022-07-20 18:20:16","AP01SDTM":"2019-07-21 00:20:16","AP01EDTM":"2021-07-20 12:20:16","AP02SDTM":"2021-07-20 12:20:16","AP02EDTM":"2022-07-20 18:20:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5466,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.66037,"AVALU":"U/L","BASE2":22.7551,"BASE":27.93866,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.09473,"PCHG2":-13.60016,"CHG":-8.2783,"PCHG":-29.63025,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-12 00:20:16","ADY":661,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-87","SUBJID":"id-87","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.47621,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-21 00:20:16","TRTEDTM":"2022-07-20 18:20:16","TRT01SDTM":"2019-07-21 00:20:16","TRT01EDTM":"2021-07-20 12:20:16","TRT02SDTM":"2021-07-20 12:20:16","TRT02EDTM":"2022-07-20 18:20:16","AP01SDTM":"2019-07-21 00:20:16","AP01EDTM":"2021-07-20 12:20:16","AP02SDTM":"2021-07-20 12:20:16","AP02EDTM":"2022-07-20 18:20:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2477,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.27434,"AVALU":"U/L","BASE2":22.7551,"BASE":27.93866,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.51924,"PCHG2":28.64958,"CHG":1.33567,"PCHG":4.78073,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-03 00:20:16","ADY":866,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-87","SUBJID":"id-87","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.47621,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-21 00:20:16","TRTEDTM":"2022-07-20 18:20:16","TRT01SDTM":"2019-07-21 00:20:16","TRT01EDTM":"2021-07-20 12:20:16","TRT02SDTM":"2021-07-20 12:20:16","TRT02EDTM":"2022-07-20 18:20:16","AP01SDTM":"2019-07-21 00:20:16","AP01EDTM":"2021-07-20 12:20:16","AP02SDTM":"2021-07-20 12:20:16","AP02EDTM":"2022-07-20 18:20:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3259,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.35103,"AVALU":"U/L","BASE2":22.7551,"BASE":27.93866,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.59594,"PCHG2":46.56511,"CHG":5.41237,"PCHG":19.37232,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-22 00:20:16","ADY":1036,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-87","SUBJID":"id-87","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.47621,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-21 00:20:16","TRTEDTM":"2022-07-20 18:20:16","TRT01SDTM":"2019-07-21 00:20:16","TRT01EDTM":"2021-07-20 12:20:16","TRT02SDTM":"2021-07-20 12:20:16","TRT02EDTM":"2022-07-20 18:20:16","AP01SDTM":"2019-07-21 00:20:16","AP01EDTM":"2021-07-20 12:20:16","AP02SDTM":"2021-07-20 12:20:16","AP02EDTM":"2022-07-20 18:20:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":563,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.22076,"AVALU":"mg/L","BASE2":9.22076,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2019-11-22 00:20:16","ADY":124,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-87","SUBJID":"id-87","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.47621,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-21 00:20:16","TRTEDTM":"2022-07-20 18:20:16","TRT01SDTM":"2019-07-21 00:20:16","TRT01EDTM":"2021-07-20 12:20:16","TRT02SDTM":"2021-07-20 12:20:16","TRT02EDTM":"2022-07-20 18:20:16","AP01SDTM":"2019-07-21 00:20:16","AP01EDTM":"2021-07-20 12:20:16","AP02SDTM":"2021-07-20 12:20:16","AP02EDTM":"2022-07-20 18:20:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2765,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.08204,"AVALU":"mg/L","BASE2":9.22076,"BASE":10.08204,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.86128,"PCHG2":9.34065,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2019-12-14 00:20:16","ADY":146,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-87","SUBJID":"id-87","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.47621,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-21 00:20:16","TRTEDTM":"2022-07-20 18:20:16","TRT01SDTM":"2019-07-21 00:20:16","TRT01EDTM":"2021-07-20 12:20:16","TRT02SDTM":"2021-07-20 12:20:16","TRT02EDTM":"2022-07-20 18:20:16","AP01SDTM":"2019-07-21 00:20:16","AP01EDTM":"2021-07-20 12:20:16","AP02SDTM":"2021-07-20 12:20:16","AP02EDTM":"2022-07-20 18:20:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6111,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.98893,"AVALU":"mg/L","BASE2":9.22076,"BASE":10.08204,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.23184,"PCHG2":-24.20447,"CHG":-3.09312,"PCHG":-30.67946,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-2","BTOXGR":"1","ADTM":"2020-04-19 00:20:16","ADY":273,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-87","SUBJID":"id-87","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.47621,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-21 00:20:16","TRTEDTM":"2022-07-20 18:20:16","TRT01SDTM":"2019-07-21 00:20:16","TRT01EDTM":"2021-07-20 12:20:16","TRT02SDTM":"2021-07-20 12:20:16","TRT02EDTM":"2022-07-20 18:20:16","AP01SDTM":"2019-07-21 00:20:16","AP01EDTM":"2021-07-20 12:20:16","AP02SDTM":"2021-07-20 12:20:16","AP02EDTM":"2022-07-20 18:20:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6378,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.55428,"AVALU":"mg/L","BASE2":9.22076,"BASE":10.08204,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.66649,"PCHG2":-28.9183,"CHG":-3.52777,"PCHG":-34.9906,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-1","BTOXGR":"1","ADTM":"2021-02-02 00:20:16","ADY":562,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-87","SUBJID":"id-87","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.47621,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-21 00:20:16","TRTEDTM":"2022-07-20 18:20:16","TRT01SDTM":"2019-07-21 00:20:16","TRT01EDTM":"2021-07-20 12:20:16","TRT02SDTM":"2021-07-20 12:20:16","TRT02EDTM":"2022-07-20 18:20:16","AP01SDTM":"2019-07-21 00:20:16","AP01EDTM":"2021-07-20 12:20:16","AP02SDTM":"2021-07-20 12:20:16","AP02EDTM":"2022-07-20 18:20:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5380,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.57521,"AVALU":"mg/L","BASE2":9.22076,"BASE":10.08204,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.64556,"PCHG2":-7.00113,"CHG":-1.50684,"PCHG":-14.94575,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-05-12 00:20:16","ADY":661,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-87","SUBJID":"id-87","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.47621,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-21 00:20:16","TRTEDTM":"2022-07-20 18:20:16","TRT01SDTM":"2019-07-21 00:20:16","TRT01EDTM":"2021-07-20 12:20:16","TRT02SDTM":"2021-07-20 12:20:16","TRT02EDTM":"2022-07-20 18:20:16","AP01SDTM":"2019-07-21 00:20:16","AP01EDTM":"2021-07-20 12:20:16","AP02SDTM":"2021-07-20 12:20:16","AP02EDTM":"2022-07-20 18:20:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5154,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.00452,"AVALU":"mg/L","BASE2":9.22076,"BASE":10.08204,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21625,"PCHG2":-2.34524,"CHG":-1.07753,"PCHG":-10.6876,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-12-03 00:20:16","ADY":866,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-87","SUBJID":"id-87","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.47621,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-21 00:20:16","TRTEDTM":"2022-07-20 18:20:16","TRT01SDTM":"2019-07-21 00:20:16","TRT01EDTM":"2021-07-20 12:20:16","TRT02SDTM":"2021-07-20 12:20:16","TRT02EDTM":"2022-07-20 18:20:16","AP01SDTM":"2019-07-21 00:20:16","AP01EDTM":"2021-07-20 12:20:16","AP02SDTM":"2021-07-20 12:20:16","AP02EDTM":"2022-07-20 18:20:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3228,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.35815,"AVALU":"mg/L","BASE2":9.22076,"BASE":10.08204,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13738,"PCHG2":1.48991,"CHG":-0.7239,"PCHG":-7.18008,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2022-05-22 00:20:16","ADY":1036,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-87","SUBJID":"id-87","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.47621,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-21 00:20:16","TRTEDTM":"2022-07-20 18:20:16","TRT01SDTM":"2019-07-21 00:20:16","TRT01EDTM":"2021-07-20 12:20:16","TRT02SDTM":"2021-07-20 12:20:16","TRT02EDTM":"2022-07-20 18:20:16","AP01SDTM":"2019-07-21 00:20:16","AP01EDTM":"2021-07-20 12:20:16","AP02SDTM":"2021-07-20 12:20:16","AP02EDTM":"2022-07-20 18:20:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":572,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87997,"AVALU":"g/L","BASE2":2.87997,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-22 00:20:16","ADY":124,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-87","SUBJID":"id-87","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.47621,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-21 00:20:16","TRTEDTM":"2022-07-20 18:20:16","TRT01SDTM":"2019-07-21 00:20:16","TRT01EDTM":"2021-07-20 12:20:16","TRT02SDTM":"2021-07-20 12:20:16","TRT02EDTM":"2022-07-20 18:20:16","AP01SDTM":"2019-07-21 00:20:16","AP01EDTM":"2021-07-20 12:20:16","AP02SDTM":"2021-07-20 12:20:16","AP02EDTM":"2022-07-20 18:20:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4696,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.6996,"AVALU":"g/L","BASE2":2.87997,"BASE":2.6996,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.18037,"PCHG2":-6.26283,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-14 00:20:16","ADY":146,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-87","SUBJID":"id-87","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.47621,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-21 00:20:16","TRTEDTM":"2022-07-20 18:20:16","TRT01SDTM":"2019-07-21 00:20:16","TRT01EDTM":"2021-07-20 12:20:16","TRT02SDTM":"2021-07-20 12:20:16","TRT02EDTM":"2022-07-20 18:20:16","AP01SDTM":"2019-07-21 00:20:16","AP01EDTM":"2021-07-20 12:20:16","AP02SDTM":"2021-07-20 12:20:16","AP02EDTM":"2022-07-20 18:20:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":805,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87186,"AVALU":"g/L","BASE2":2.87997,"BASE":2.6996,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00811,"PCHG2":-0.28174,"CHG":0.17225,"PCHG":6.3807,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-19 00:20:16","ADY":273,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-87","SUBJID":"id-87","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.47621,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-21 00:20:16","TRTEDTM":"2022-07-20 18:20:16","TRT01SDTM":"2019-07-21 00:20:16","TRT01EDTM":"2021-07-20 12:20:16","TRT02SDTM":"2021-07-20 12:20:16","TRT02EDTM":"2022-07-20 18:20:16","AP01SDTM":"2019-07-21 00:20:16","AP01EDTM":"2021-07-20 12:20:16","AP02SDTM":"2021-07-20 12:20:16","AP02EDTM":"2022-07-20 18:20:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2991,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82963,"AVALU":"g/L","BASE2":2.87997,"BASE":2.6996,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05034,"PCHG2":-1.74795,"CHG":0.13003,"PCHG":4.81653,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-02 00:20:16","ADY":562,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-87","SUBJID":"id-87","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.47621,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-21 00:20:16","TRTEDTM":"2022-07-20 18:20:16","TRT01SDTM":"2019-07-21 00:20:16","TRT01EDTM":"2021-07-20 12:20:16","TRT02SDTM":"2021-07-20 12:20:16","TRT02EDTM":"2022-07-20 18:20:16","AP01SDTM":"2019-07-21 00:20:16","AP01EDTM":"2021-07-20 12:20:16","AP02SDTM":"2021-07-20 12:20:16","AP02EDTM":"2022-07-20 18:20:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":279,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81276,"AVALU":"g/L","BASE2":2.87997,"BASE":2.6996,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06722,"PCHG2":-2.33396,"CHG":0.11315,"PCHG":4.19136,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-12 00:20:16","ADY":661,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-87","SUBJID":"id-87","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.47621,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-21 00:20:16","TRTEDTM":"2022-07-20 18:20:16","TRT01SDTM":"2019-07-21 00:20:16","TRT01EDTM":"2021-07-20 12:20:16","TRT02SDTM":"2021-07-20 12:20:16","TRT02EDTM":"2022-07-20 18:20:16","AP01SDTM":"2019-07-21 00:20:16","AP01EDTM":"2021-07-20 12:20:16","AP02SDTM":"2021-07-20 12:20:16","AP02EDTM":"2022-07-20 18:20:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5607,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94914,"AVALU":"g/L","BASE2":2.87997,"BASE":2.6996,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06917,"PCHG2":2.40181,"CHG":0.24954,"PCHG":9.24354,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-03 00:20:16","ADY":866,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-11-id-87","SUBJID":"id-87","SITEID":"PAK-11","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-11","INVNAM":"Dr. PAK-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":13.47621,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-21 00:20:16","TRTEDTM":"2022-07-20 18:20:16","TRT01SDTM":"2019-07-21 00:20:16","TRT01EDTM":"2021-07-20 12:20:16","TRT02SDTM":"2021-07-20 12:20:16","TRT02EDTM":"2022-07-20 18:20:16","AP01SDTM":"2019-07-21 00:20:16","AP01EDTM":"2021-07-20 12:20:16","AP02SDTM":"2021-07-20 12:20:16","AP02EDTM":"2022-07-20 18:20:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-20","EOSDY":1096,"LSTALVDT":"2022-08-12","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5171,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93041,"AVALU":"g/L","BASE2":2.87997,"BASE":2.6996,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05044,"PCHG2":1.7513,"CHG":0.2308,"PCHG":8.54957,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-22 00:20:16","ADY":1036,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-328","SUBJID":"id-328","SITEID":"PAK-12","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.04077,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-10","TRTSDTM":"2019-09-10 10:48:40","TRTEDTM":"2022-09-10 04:48:40","TRT01SDTM":"2019-09-10 10:48:40","TRT01EDTM":"2021-09-09 22:48:40","TRT02SDTM":"2021-09-09 22:48:40","TRT02EDTM":"2022-09-10 04:48:40","AP01SDTM":"2019-09-10 10:48:40","AP01EDTM":"2021-09-09 22:48:40","AP02SDTM":"2021-09-09 22:48:40","AP02EDTM":"2022-09-10 04:48:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-10","EOSDY":1096,"LSTALVDT":"2022-10-01","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":208,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.58486,"AVALU":"U/L","BASE2":23.58486,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-21 10:48:40","ADY":224,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-328","SUBJID":"id-328","SITEID":"PAK-12","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.04077,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-10","TRTSDTM":"2019-09-10 10:48:40","TRTEDTM":"2022-09-10 04:48:40","TRT01SDTM":"2019-09-10 10:48:40","TRT01EDTM":"2021-09-09 22:48:40","TRT02SDTM":"2021-09-09 22:48:40","TRT02EDTM":"2022-09-10 04:48:40","AP01SDTM":"2019-09-10 10:48:40","AP01EDTM":"2021-09-09 22:48:40","AP02SDTM":"2021-09-09 22:48:40","AP02EDTM":"2022-09-10 04:48:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-10","EOSDY":1096,"LSTALVDT":"2022-10-01","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":62,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.45997,"AVALU":"U/L","BASE2":23.58486,"BASE":17.45997,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-6.12489,"PCHG2":-25.96958,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-12 10:48:40","ADY":306,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-328","SUBJID":"id-328","SITEID":"PAK-12","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.04077,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-10","TRTSDTM":"2019-09-10 10:48:40","TRTEDTM":"2022-09-10 04:48:40","TRT01SDTM":"2019-09-10 10:48:40","TRT01EDTM":"2021-09-09 22:48:40","TRT02SDTM":"2021-09-09 22:48:40","TRT02EDTM":"2022-09-10 04:48:40","AP01SDTM":"2019-09-10 10:48:40","AP01EDTM":"2021-09-09 22:48:40","AP02SDTM":"2021-09-09 22:48:40","AP02EDTM":"2022-09-10 04:48:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-10","EOSDY":1096,"LSTALVDT":"2022-10-01","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3497,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.28165,"AVALU":"U/L","BASE2":23.58486,"BASE":17.45997,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.30322,"PCHG2":-30.9657,"CHG":-1.17833,"PCHG":-6.74873,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-09 10:48:40","ADY":395,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-328","SUBJID":"id-328","SITEID":"PAK-12","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.04077,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-10","TRTSDTM":"2019-09-10 10:48:40","TRTEDTM":"2022-09-10 04:48:40","TRT01SDTM":"2019-09-10 10:48:40","TRT01EDTM":"2021-09-09 22:48:40","TRT02SDTM":"2021-09-09 22:48:40","TRT02EDTM":"2022-09-10 04:48:40","AP01SDTM":"2019-09-10 10:48:40","AP01EDTM":"2021-09-09 22:48:40","AP02SDTM":"2021-09-09 22:48:40","AP02EDTM":"2022-09-10 04:48:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-10","EOSDY":1096,"LSTALVDT":"2022-10-01","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5325,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.94845,"AVALU":"U/L","BASE2":23.58486,"BASE":17.45997,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.63641,"PCHG2":-32.37845,"CHG":-1.51152,"PCHG":-8.65708,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-30 10:48:40","ADY":416,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-328","SUBJID":"id-328","SITEID":"PAK-12","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.04077,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-10","TRTSDTM":"2019-09-10 10:48:40","TRTEDTM":"2022-09-10 04:48:40","TRT01SDTM":"2019-09-10 10:48:40","TRT01EDTM":"2021-09-09 22:48:40","TRT02SDTM":"2021-09-09 22:48:40","TRT02EDTM":"2022-09-10 04:48:40","AP01SDTM":"2019-09-10 10:48:40","AP01EDTM":"2021-09-09 22:48:40","AP02SDTM":"2021-09-09 22:48:40","AP02EDTM":"2022-09-10 04:48:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-10","EOSDY":1096,"LSTALVDT":"2022-10-01","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4170,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.06798,"AVALU":"U/L","BASE2":23.58486,"BASE":17.45997,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.51689,"PCHG2":-2.19161,"CHG":5.608,"PCHG":32.11918,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-18 10:48:40","ADY":435,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-328","SUBJID":"id-328","SITEID":"PAK-12","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.04077,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-10","TRTSDTM":"2019-09-10 10:48:40","TRTEDTM":"2022-09-10 04:48:40","TRT01SDTM":"2019-09-10 10:48:40","TRT01EDTM":"2021-09-09 22:48:40","TRT02SDTM":"2021-09-09 22:48:40","TRT02EDTM":"2022-09-10 04:48:40","AP01SDTM":"2019-09-10 10:48:40","AP01EDTM":"2021-09-09 22:48:40","AP02SDTM":"2021-09-09 22:48:40","AP02EDTM":"2022-09-10 04:48:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-10","EOSDY":1096,"LSTALVDT":"2022-10-01","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2108,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.69563,"AVALU":"U/L","BASE2":23.58486,"BASE":17.45997,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-20.88923,"PCHG2":-88.57051,"CHG":-14.76434,"PCHG":-84.56109,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-04-02 10:48:40","ADY":570,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-328","SUBJID":"id-328","SITEID":"PAK-12","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.04077,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-10","TRTSDTM":"2019-09-10 10:48:40","TRTEDTM":"2022-09-10 04:48:40","TRT01SDTM":"2019-09-10 10:48:40","TRT01EDTM":"2021-09-09 22:48:40","TRT02SDTM":"2021-09-09 22:48:40","TRT02EDTM":"2022-09-10 04:48:40","AP01SDTM":"2019-09-10 10:48:40","AP01EDTM":"2021-09-09 22:48:40","AP02SDTM":"2021-09-09 22:48:40","AP02EDTM":"2022-09-10 04:48:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-10","EOSDY":1096,"LSTALVDT":"2022-10-01","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4286,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.05439,"AVALU":"U/L","BASE2":23.58486,"BASE":17.45997,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.46953,"PCHG2":6.23081,"CHG":7.59442,"PCHG":43.49616,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-22 10:48:40","ADY":620,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-328","SUBJID":"id-328","SITEID":"PAK-12","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.04077,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-10","TRTSDTM":"2019-09-10 10:48:40","TRTEDTM":"2022-09-10 04:48:40","TRT01SDTM":"2019-09-10 10:48:40","TRT01EDTM":"2021-09-09 22:48:40","TRT02SDTM":"2021-09-09 22:48:40","TRT02EDTM":"2022-09-10 04:48:40","AP01SDTM":"2019-09-10 10:48:40","AP01EDTM":"2021-09-09 22:48:40","AP02SDTM":"2021-09-09 22:48:40","AP02EDTM":"2022-09-10 04:48:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-10","EOSDY":1096,"LSTALVDT":"2022-10-01","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":787,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.7005,"AVALU":"mg/L","BASE2":10.7005,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-04-21 10:48:40","ADY":224,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-328","SUBJID":"id-328","SITEID":"PAK-12","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.04077,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-10","TRTSDTM":"2019-09-10 10:48:40","TRTEDTM":"2022-09-10 04:48:40","TRT01SDTM":"2019-09-10 10:48:40","TRT01EDTM":"2021-09-09 22:48:40","TRT02SDTM":"2021-09-09 22:48:40","TRT02EDTM":"2022-09-10 04:48:40","AP01SDTM":"2019-09-10 10:48:40","AP01EDTM":"2021-09-09 22:48:40","AP02SDTM":"2021-09-09 22:48:40","AP02EDTM":"2022-09-10 04:48:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-10","EOSDY":1096,"LSTALVDT":"2022-10-01","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1982,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.79058,"AVALU":"mg/L","BASE2":10.7005,"BASE":8.79058,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.90992,"PCHG2":-17.84885,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-12 10:48:40","ADY":306,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-328","SUBJID":"id-328","SITEID":"PAK-12","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.04077,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-10","TRTSDTM":"2019-09-10 10:48:40","TRTEDTM":"2022-09-10 04:48:40","TRT01SDTM":"2019-09-10 10:48:40","TRT01EDTM":"2021-09-09 22:48:40","TRT02SDTM":"2021-09-09 22:48:40","TRT02EDTM":"2022-09-10 04:48:40","AP01SDTM":"2019-09-10 10:48:40","AP01EDTM":"2021-09-09 22:48:40","AP02SDTM":"2021-09-09 22:48:40","AP02EDTM":"2022-09-10 04:48:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-10","EOSDY":1096,"LSTALVDT":"2022-10-01","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2144,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.87283,"AVALU":"mg/L","BASE2":10.7005,"BASE":8.79058,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.82766,"PCHG2":-7.73479,"CHG":1.08225,"PCHG":12.31153,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-09 10:48:40","ADY":395,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-328","SUBJID":"id-328","SITEID":"PAK-12","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.04077,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-10","TRTSDTM":"2019-09-10 10:48:40","TRTEDTM":"2022-09-10 04:48:40","TRT01SDTM":"2019-09-10 10:48:40","TRT01EDTM":"2021-09-09 22:48:40","TRT02SDTM":"2021-09-09 22:48:40","TRT02EDTM":"2022-09-10 04:48:40","AP01SDTM":"2019-09-10 10:48:40","AP01EDTM":"2021-09-09 22:48:40","AP02SDTM":"2021-09-09 22:48:40","AP02EDTM":"2022-09-10 04:48:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-10","EOSDY":1096,"LSTALVDT":"2022-10-01","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7914,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.07496,"AVALU":"mg/L","BASE2":10.7005,"BASE":8.79058,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.62553,"PCHG2":-5.84585,"CHG":1.28438,"PCHG":14.61088,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-10-30 10:48:40","ADY":416,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-328","SUBJID":"id-328","SITEID":"PAK-12","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.04077,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-10","TRTSDTM":"2019-09-10 10:48:40","TRTEDTM":"2022-09-10 04:48:40","TRT01SDTM":"2019-09-10 10:48:40","TRT01EDTM":"2021-09-09 22:48:40","TRT02SDTM":"2021-09-09 22:48:40","TRT02EDTM":"2022-09-10 04:48:40","AP01SDTM":"2019-09-10 10:48:40","AP01EDTM":"2021-09-09 22:48:40","AP02SDTM":"2021-09-09 22:48:40","AP02EDTM":"2022-09-10 04:48:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-10","EOSDY":1096,"LSTALVDT":"2022-10-01","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5470,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.51647,"AVALU":"mg/L","BASE2":10.7005,"BASE":8.79058,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.18402,"PCHG2":-20.4105,"CHG":-0.27411,"PCHG":-3.11822,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-18 10:48:40","ADY":435,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-328","SUBJID":"id-328","SITEID":"PAK-12","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.04077,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-10","TRTSDTM":"2019-09-10 10:48:40","TRTEDTM":"2022-09-10 04:48:40","TRT01SDTM":"2019-09-10 10:48:40","TRT01EDTM":"2021-09-09 22:48:40","TRT02SDTM":"2021-09-09 22:48:40","TRT02EDTM":"2022-09-10 04:48:40","AP01SDTM":"2019-09-10 10:48:40","AP01EDTM":"2021-09-09 22:48:40","AP02SDTM":"2021-09-09 22:48:40","AP02EDTM":"2022-09-10 04:48:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-10","EOSDY":1096,"LSTALVDT":"2022-10-01","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7630,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.16446,"AVALU":"mg/L","BASE2":10.7005,"BASE":8.79058,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.53604,"PCHG2":-23.70017,"CHG":-0.62612,"PCHG":-7.12263,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-02 10:48:40","ADY":570,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-328","SUBJID":"id-328","SITEID":"PAK-12","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.04077,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-10","TRTSDTM":"2019-09-10 10:48:40","TRTEDTM":"2022-09-10 04:48:40","TRT01SDTM":"2019-09-10 10:48:40","TRT01EDTM":"2021-09-09 22:48:40","TRT02SDTM":"2021-09-09 22:48:40","TRT02EDTM":"2022-09-10 04:48:40","AP01SDTM":"2019-09-10 10:48:40","AP01EDTM":"2021-09-09 22:48:40","AP02SDTM":"2021-09-09 22:48:40","AP02EDTM":"2022-09-10 04:48:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-10","EOSDY":1096,"LSTALVDT":"2022-10-01","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6816,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.24778,"AVALU":"mg/L","BASE2":10.7005,"BASE":8.79058,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.45272,"PCHG2":-32.26688,"CHG":-1.5428,"PCHG":-17.55061,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-05-22 10:48:40","ADY":620,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-328","SUBJID":"id-328","SITEID":"PAK-12","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.04077,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-10","TRTSDTM":"2019-09-10 10:48:40","TRTEDTM":"2022-09-10 04:48:40","TRT01SDTM":"2019-09-10 10:48:40","TRT01EDTM":"2021-09-09 22:48:40","TRT02SDTM":"2021-09-09 22:48:40","TRT02EDTM":"2022-09-10 04:48:40","AP01SDTM":"2019-09-10 10:48:40","AP01EDTM":"2021-09-09 22:48:40","AP02SDTM":"2021-09-09 22:48:40","AP02EDTM":"2022-09-10 04:48:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-10","EOSDY":1096,"LSTALVDT":"2022-10-01","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":919,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02058,"AVALU":"g/L","BASE2":3.02058,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-04-21 10:48:40","ADY":224,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-328","SUBJID":"id-328","SITEID":"PAK-12","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.04077,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-10","TRTSDTM":"2019-09-10 10:48:40","TRTEDTM":"2022-09-10 04:48:40","TRT01SDTM":"2019-09-10 10:48:40","TRT01EDTM":"2021-09-09 22:48:40","TRT02SDTM":"2021-09-09 22:48:40","TRT02EDTM":"2022-09-10 04:48:40","AP01SDTM":"2019-09-10 10:48:40","AP01EDTM":"2021-09-09 22:48:40","AP02SDTM":"2021-09-09 22:48:40","AP02EDTM":"2022-09-10 04:48:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-10","EOSDY":1096,"LSTALVDT":"2022-10-01","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4885,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8545,"AVALU":"g/L","BASE2":3.02058,"BASE":2.8545,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.16608,"PCHG2":-5.49841,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-12 10:48:40","ADY":306,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-328","SUBJID":"id-328","SITEID":"PAK-12","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.04077,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-10","TRTSDTM":"2019-09-10 10:48:40","TRTEDTM":"2022-09-10 04:48:40","TRT01SDTM":"2019-09-10 10:48:40","TRT01EDTM":"2021-09-09 22:48:40","TRT02SDTM":"2021-09-09 22:48:40","TRT02EDTM":"2022-09-10 04:48:40","AP01SDTM":"2019-09-10 10:48:40","AP01EDTM":"2021-09-09 22:48:40","AP02SDTM":"2021-09-09 22:48:40","AP02EDTM":"2022-09-10 04:48:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-10","EOSDY":1096,"LSTALVDT":"2022-10-01","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":823,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89375,"AVALU":"g/L","BASE2":3.02058,"BASE":2.8545,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12684,"PCHG2":-4.19908,"CHG":0.03925,"PCHG":1.37493,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-09 10:48:40","ADY":395,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-328","SUBJID":"id-328","SITEID":"PAK-12","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.04077,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-10","TRTSDTM":"2019-09-10 10:48:40","TRTEDTM":"2022-09-10 04:48:40","TRT01SDTM":"2019-09-10 10:48:40","TRT01EDTM":"2021-09-09 22:48:40","TRT02SDTM":"2021-09-09 22:48:40","TRT02EDTM":"2022-09-10 04:48:40","AP01SDTM":"2019-09-10 10:48:40","AP01EDTM":"2021-09-09 22:48:40","AP02SDTM":"2021-09-09 22:48:40","AP02EDTM":"2022-09-10 04:48:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-10","EOSDY":1096,"LSTALVDT":"2022-10-01","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3919,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99086,"AVALU":"g/L","BASE2":3.02058,"BASE":2.8545,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02972,"PCHG2":-0.98389,"CHG":0.13636,"PCHG":4.77719,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-30 10:48:40","ADY":416,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-328","SUBJID":"id-328","SITEID":"PAK-12","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.04077,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-10","TRTSDTM":"2019-09-10 10:48:40","TRTEDTM":"2022-09-10 04:48:40","TRT01SDTM":"2019-09-10 10:48:40","TRT01EDTM":"2021-09-09 22:48:40","TRT02SDTM":"2021-09-09 22:48:40","TRT02EDTM":"2022-09-10 04:48:40","AP01SDTM":"2019-09-10 10:48:40","AP01EDTM":"2021-09-09 22:48:40","AP02SDTM":"2021-09-09 22:48:40","AP02EDTM":"2022-09-10 04:48:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-10","EOSDY":1096,"LSTALVDT":"2022-10-01","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5955,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99112,"AVALU":"g/L","BASE2":3.02058,"BASE":2.8545,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02946,"PCHG2":-0.97538,"CHG":0.13662,"PCHG":4.7862,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-18 10:48:40","ADY":435,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-328","SUBJID":"id-328","SITEID":"PAK-12","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.04077,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-10","TRTSDTM":"2019-09-10 10:48:40","TRTEDTM":"2022-09-10 04:48:40","TRT01SDTM":"2019-09-10 10:48:40","TRT01EDTM":"2021-09-09 22:48:40","TRT02SDTM":"2021-09-09 22:48:40","TRT02EDTM":"2022-09-10 04:48:40","AP01SDTM":"2019-09-10 10:48:40","AP01EDTM":"2021-09-09 22:48:40","AP02SDTM":"2021-09-09 22:48:40","AP02EDTM":"2022-09-10 04:48:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-10","EOSDY":1096,"LSTALVDT":"2022-10-01","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5307,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92018,"AVALU":"g/L","BASE2":3.02058,"BASE":2.8545,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1004,"PCHG2":-3.32395,"CHG":0.06568,"PCHG":2.30098,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-02 10:48:40","ADY":570,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-328","SUBJID":"id-328","SITEID":"PAK-12","AGE":21,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":9.04077,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-09-10","TRTSDTM":"2019-09-10 10:48:40","TRTEDTM":"2022-09-10 04:48:40","TRT01SDTM":"2019-09-10 10:48:40","TRT01EDTM":"2021-09-09 22:48:40","TRT02SDTM":"2021-09-09 22:48:40","TRT02EDTM":"2022-09-10 04:48:40","AP01SDTM":"2019-09-10 10:48:40","AP01EDTM":"2021-09-09 22:48:40","AP02SDTM":"2021-09-09 22:48:40","AP02EDTM":"2022-09-10 04:48:40","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-09-10","EOSDY":1096,"LSTALVDT":"2022-10-01","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1309,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85372,"AVALU":"g/L","BASE2":3.02058,"BASE":2.8545,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16686,"PCHG2":-5.52411,"CHG":-0.00078,"PCHG":-0.02719,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-22 10:48:40","ADY":620,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-85","SUBJID":"id-85","SITEID":"PAK-12","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.6978,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-06","TRTSDTM":"2020-09-09 04:06:54","TRTEDTM":"2022-02-14 08:34:04","TRT01SDTM":"2020-09-09 04:06:54","TRT01EDTM":"2021-02-14 02:34:04","TRT02SDTM":"2021-02-14 02:34:04","TRT02EDTM":"2022-02-14 08:34:04","AP01SDTM":"2020-09-09 04:06:54","AP01EDTM":"2021-02-14 02:34:04","AP02SDTM":"2021-02-14 02:34:04","AP02EDTM":"2022-02-14 08:34:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":524,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-06","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4937,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.23007,"AVALU":"U/L","BASE2":21.23007,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-02 04:06:54","ADY":84,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-85","SUBJID":"id-85","SITEID":"PAK-12","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.6978,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-06","TRTSDTM":"2020-09-09 04:06:54","TRTEDTM":"2022-02-14 08:34:04","TRT01SDTM":"2020-09-09 04:06:54","TRT01EDTM":"2021-02-14 02:34:04","TRT02SDTM":"2021-02-14 02:34:04","TRT02EDTM":"2022-02-14 08:34:04","AP01SDTM":"2020-09-09 04:06:54","AP01EDTM":"2021-02-14 02:34:04","AP02SDTM":"2021-02-14 02:34:04","AP02EDTM":"2022-02-14 08:34:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":524,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-06","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7654,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.15065,"AVALU":"U/L","BASE2":21.23007,"BASE":24.15065,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.92058,"PCHG2":13.75682,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-05 04:06:54","ADY":87,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-85","SUBJID":"id-85","SITEID":"PAK-12","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.6978,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-06","TRTSDTM":"2020-09-09 04:06:54","TRTEDTM":"2022-02-14 08:34:04","TRT01SDTM":"2020-09-09 04:06:54","TRT01EDTM":"2021-02-14 02:34:04","TRT02SDTM":"2021-02-14 02:34:04","TRT02EDTM":"2022-02-14 08:34:04","AP01SDTM":"2020-09-09 04:06:54","AP01EDTM":"2021-02-14 02:34:04","AP02SDTM":"2021-02-14 02:34:04","AP02EDTM":"2022-02-14 08:34:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":524,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-06","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5900,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.79403,"AVALU":"U/L","BASE2":21.23007,"BASE":24.15065,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.43603,"PCHG2":-58.57746,"CHG":-15.35661,"PCHG":-63.58676,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-12 04:06:54","ADY":94,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-85","SUBJID":"id-85","SITEID":"PAK-12","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.6978,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-06","TRTSDTM":"2020-09-09 04:06:54","TRTEDTM":"2022-02-14 08:34:04","TRT01SDTM":"2020-09-09 04:06:54","TRT01EDTM":"2021-02-14 02:34:04","TRT02SDTM":"2021-02-14 02:34:04","TRT02EDTM":"2022-02-14 08:34:04","AP01SDTM":"2020-09-09 04:06:54","AP01EDTM":"2021-02-14 02:34:04","AP02SDTM":"2021-02-14 02:34:04","AP02EDTM":"2022-02-14 08:34:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":524,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-06","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3507,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.17465,"AVALU":"U/L","BASE2":21.23007,"BASE":24.15065,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.94459,"PCHG2":28.0008,"CHG":3.02401,"PCHG":12.52143,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-17 04:06:54","ADY":250,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-85","SUBJID":"id-85","SITEID":"PAK-12","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.6978,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-06","TRTSDTM":"2020-09-09 04:06:54","TRTEDTM":"2022-02-14 08:34:04","TRT01SDTM":"2020-09-09 04:06:54","TRT01EDTM":"2021-02-14 02:34:04","TRT02SDTM":"2021-02-14 02:34:04","TRT02EDTM":"2022-02-14 08:34:04","AP01SDTM":"2020-09-09 04:06:54","AP01EDTM":"2021-02-14 02:34:04","AP02SDTM":"2021-02-14 02:34:04","AP02EDTM":"2022-02-14 08:34:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":524,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-06","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3011,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.05554,"AVALU":"U/L","BASE2":21.23007,"BASE":24.15065,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.17452,"PCHG2":-43.21476,"CHG":-12.0951,"PCHG":-50.0819,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-22 04:06:54","ADY":347,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-85","SUBJID":"id-85","SITEID":"PAK-12","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.6978,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-06","TRTSDTM":"2020-09-09 04:06:54","TRTEDTM":"2022-02-14 08:34:04","TRT01SDTM":"2020-09-09 04:06:54","TRT01EDTM":"2021-02-14 02:34:04","TRT02SDTM":"2021-02-14 02:34:04","TRT02EDTM":"2022-02-14 08:34:04","AP01SDTM":"2020-09-09 04:06:54","AP01EDTM":"2021-02-14 02:34:04","AP02SDTM":"2021-02-14 02:34:04","AP02EDTM":"2022-02-14 08:34:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":524,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-06","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3001,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.25256,"AVALU":"U/L","BASE2":21.23007,"BASE":24.15065,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.9775,"PCHG2":-9.31464,"CHG":-4.89809,"PCHG":-20.28138,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-03 04:06:54","ADY":359,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-85","SUBJID":"id-85","SITEID":"PAK-12","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.6978,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-06","TRTSDTM":"2020-09-09 04:06:54","TRTEDTM":"2022-02-14 08:34:04","TRT01SDTM":"2020-09-09 04:06:54","TRT01EDTM":"2021-02-14 02:34:04","TRT02SDTM":"2021-02-14 02:34:04","TRT02EDTM":"2022-02-14 08:34:04","AP01SDTM":"2020-09-09 04:06:54","AP01EDTM":"2021-02-14 02:34:04","AP02SDTM":"2021-02-14 02:34:04","AP02EDTM":"2022-02-14 08:34:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":524,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-06","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4849,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.70395,"AVALU":"U/L","BASE2":21.23007,"BASE":24.15065,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.52611,"PCHG2":-77.84296,"CHG":-19.44669,"PCHG":-80.52245,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2022-01-19 04:06:54","ADY":497,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-85","SUBJID":"id-85","SITEID":"PAK-12","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.6978,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-06","TRTSDTM":"2020-09-09 04:06:54","TRTEDTM":"2022-02-14 08:34:04","TRT01SDTM":"2020-09-09 04:06:54","TRT01EDTM":"2021-02-14 02:34:04","TRT02SDTM":"2021-02-14 02:34:04","TRT02EDTM":"2022-02-14 08:34:04","AP01SDTM":"2020-09-09 04:06:54","AP01EDTM":"2021-02-14 02:34:04","AP02SDTM":"2021-02-14 02:34:04","AP02EDTM":"2022-02-14 08:34:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":524,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-06","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5881,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.60432,"AVALU":"mg/L","BASE2":8.60432,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-12-02 04:06:54","ADY":84,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-85","SUBJID":"id-85","SITEID":"PAK-12","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.6978,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-06","TRTSDTM":"2020-09-09 04:06:54","TRTEDTM":"2022-02-14 08:34:04","TRT01SDTM":"2020-09-09 04:06:54","TRT01EDTM":"2021-02-14 02:34:04","TRT02SDTM":"2021-02-14 02:34:04","TRT02EDTM":"2022-02-14 08:34:04","AP01SDTM":"2020-09-09 04:06:54","AP01EDTM":"2021-02-14 02:34:04","AP02SDTM":"2021-02-14 02:34:04","AP02EDTM":"2022-02-14 08:34:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":524,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-06","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7980,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.1227,"AVALU":"mg/L","BASE2":8.60432,"BASE":10.1227,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.51838,"PCHG2":17.64674,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-12-05 04:06:54","ADY":87,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-85","SUBJID":"id-85","SITEID":"PAK-12","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.6978,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-06","TRTSDTM":"2020-09-09 04:06:54","TRTEDTM":"2022-02-14 08:34:04","TRT01SDTM":"2020-09-09 04:06:54","TRT01EDTM":"2021-02-14 02:34:04","TRT02SDTM":"2021-02-14 02:34:04","TRT02EDTM":"2022-02-14 08:34:04","AP01SDTM":"2020-09-09 04:06:54","AP01EDTM":"2021-02-14 02:34:04","AP02SDTM":"2021-02-14 02:34:04","AP02EDTM":"2022-02-14 08:34:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":524,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-06","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1983,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.57499,"AVALU":"mg/L","BASE2":8.60432,"BASE":10.1227,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.02933,"PCHG2":-11.96292,"CHG":-2.54771,"PCHG":-25.16828,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-4","BTOXGR":"1","ADTM":"2020-12-12 04:06:54","ADY":94,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-85","SUBJID":"id-85","SITEID":"PAK-12","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.6978,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-06","TRTSDTM":"2020-09-09 04:06:54","TRTEDTM":"2022-02-14 08:34:04","TRT01SDTM":"2020-09-09 04:06:54","TRT01EDTM":"2021-02-14 02:34:04","TRT02SDTM":"2021-02-14 02:34:04","TRT02EDTM":"2022-02-14 08:34:04","AP01SDTM":"2020-09-09 04:06:54","AP01EDTM":"2021-02-14 02:34:04","AP02SDTM":"2021-02-14 02:34:04","AP02EDTM":"2022-02-14 08:34:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":524,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-06","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3012,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.06346,"AVALU":"mg/L","BASE2":8.60432,"BASE":10.1227,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.45913,"PCHG2":5.33609,"CHG":-1.05925,"PCHG":-10.46408,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-05-17 04:06:54","ADY":250,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-85","SUBJID":"id-85","SITEID":"PAK-12","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.6978,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-06","TRTSDTM":"2020-09-09 04:06:54","TRTEDTM":"2022-02-14 08:34:04","TRT01SDTM":"2020-09-09 04:06:54","TRT01EDTM":"2021-02-14 02:34:04","TRT02SDTM":"2021-02-14 02:34:04","TRT02EDTM":"2022-02-14 08:34:04","AP01SDTM":"2020-09-09 04:06:54","AP01EDTM":"2021-02-14 02:34:04","AP02SDTM":"2021-02-14 02:34:04","AP02EDTM":"2022-02-14 08:34:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":524,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-06","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3766,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.19684,"AVALU":"mg/L","BASE2":8.60432,"BASE":10.1227,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.59251,"PCHG2":6.88624,"CHG":-0.92587,"PCHG":-9.14646,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-08-22 04:06:54","ADY":347,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-85","SUBJID":"id-85","SITEID":"PAK-12","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.6978,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-06","TRTSDTM":"2020-09-09 04:06:54","TRTEDTM":"2022-02-14 08:34:04","TRT01SDTM":"2020-09-09 04:06:54","TRT01EDTM":"2021-02-14 02:34:04","TRT02SDTM":"2021-02-14 02:34:04","TRT02EDTM":"2022-02-14 08:34:04","AP01SDTM":"2020-09-09 04:06:54","AP01EDTM":"2021-02-14 02:34:04","AP02SDTM":"2021-02-14 02:34:04","AP02EDTM":"2022-02-14 08:34:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":524,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-06","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6081,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.02214,"AVALU":"mg/L","BASE2":8.60432,"BASE":10.1227,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.41782,"PCHG2":4.85596,"CHG":-1.10056,"PCHG":-10.87219,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-09-03 04:06:54","ADY":359,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-85","SUBJID":"id-85","SITEID":"PAK-12","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.6978,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-06","TRTSDTM":"2020-09-09 04:06:54","TRTEDTM":"2022-02-14 08:34:04","TRT01SDTM":"2020-09-09 04:06:54","TRT01EDTM":"2021-02-14 02:34:04","TRT02SDTM":"2021-02-14 02:34:04","TRT02EDTM":"2022-02-14 08:34:04","AP01SDTM":"2020-09-09 04:06:54","AP01EDTM":"2021-02-14 02:34:04","AP02SDTM":"2021-02-14 02:34:04","AP02EDTM":"2022-02-14 08:34:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":524,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-06","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5180,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.81325,"AVALU":"mg/L","BASE2":8.60432,"BASE":10.1227,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.79107,"PCHG2":-9.19385,"CHG":-2.30945,"PCHG":-22.81457,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-3","BTOXGR":"1","ADTM":"2022-01-19 04:06:54","ADY":497,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-85","SUBJID":"id-85","SITEID":"PAK-12","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.6978,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-06","TRTSDTM":"2020-09-09 04:06:54","TRTEDTM":"2022-02-14 08:34:04","TRT01SDTM":"2020-09-09 04:06:54","TRT01EDTM":"2021-02-14 02:34:04","TRT02SDTM":"2021-02-14 02:34:04","TRT02EDTM":"2022-02-14 08:34:04","AP01SDTM":"2020-09-09 04:06:54","AP01EDTM":"2021-02-14 02:34:04","AP02SDTM":"2021-02-14 02:34:04","AP02EDTM":"2022-02-14 08:34:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":524,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-06","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2600,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95648,"AVALU":"g/L","BASE2":2.95648,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-02 04:06:54","ADY":84,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-85","SUBJID":"id-85","SITEID":"PAK-12","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.6978,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-06","TRTSDTM":"2020-09-09 04:06:54","TRTEDTM":"2022-02-14 08:34:04","TRT01SDTM":"2020-09-09 04:06:54","TRT01EDTM":"2021-02-14 02:34:04","TRT02SDTM":"2021-02-14 02:34:04","TRT02EDTM":"2022-02-14 08:34:04","AP01SDTM":"2020-09-09 04:06:54","AP01EDTM":"2021-02-14 02:34:04","AP02SDTM":"2021-02-14 02:34:04","AP02EDTM":"2022-02-14 08:34:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":524,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-06","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6420,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89811,"AVALU":"g/L","BASE2":2.95648,"BASE":2.89811,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.05838,"PCHG2":-1.97451,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-05 04:06:54","ADY":87,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-85","SUBJID":"id-85","SITEID":"PAK-12","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.6978,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-06","TRTSDTM":"2020-09-09 04:06:54","TRTEDTM":"2022-02-14 08:34:04","TRT01SDTM":"2020-09-09 04:06:54","TRT01EDTM":"2021-02-14 02:34:04","TRT02SDTM":"2021-02-14 02:34:04","TRT02EDTM":"2022-02-14 08:34:04","AP01SDTM":"2020-09-09 04:06:54","AP01EDTM":"2021-02-14 02:34:04","AP02SDTM":"2021-02-14 02:34:04","AP02EDTM":"2022-02-14 08:34:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":524,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-06","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1997,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77964,"AVALU":"g/L","BASE2":2.95648,"BASE":2.89811,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17684,"PCHG2":-5.98159,"CHG":-0.11847,"PCHG":-4.0878,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-12 04:06:54","ADY":94,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-85","SUBJID":"id-85","SITEID":"PAK-12","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.6978,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-06","TRTSDTM":"2020-09-09 04:06:54","TRTEDTM":"2022-02-14 08:34:04","TRT01SDTM":"2020-09-09 04:06:54","TRT01EDTM":"2021-02-14 02:34:04","TRT02SDTM":"2021-02-14 02:34:04","TRT02EDTM":"2022-02-14 08:34:04","AP01SDTM":"2020-09-09 04:06:54","AP01EDTM":"2021-02-14 02:34:04","AP02SDTM":"2021-02-14 02:34:04","AP02EDTM":"2022-02-14 08:34:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":524,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-06","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4448,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93769,"AVALU":"g/L","BASE2":2.95648,"BASE":2.89811,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0188,"PCHG2":-0.63583,"CHG":0.03958,"PCHG":1.36564,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-17 04:06:54","ADY":250,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-85","SUBJID":"id-85","SITEID":"PAK-12","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.6978,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-06","TRTSDTM":"2020-09-09 04:06:54","TRTEDTM":"2022-02-14 08:34:04","TRT01SDTM":"2020-09-09 04:06:54","TRT01EDTM":"2021-02-14 02:34:04","TRT02SDTM":"2021-02-14 02:34:04","TRT02EDTM":"2022-02-14 08:34:04","AP01SDTM":"2020-09-09 04:06:54","AP01EDTM":"2021-02-14 02:34:04","AP02SDTM":"2021-02-14 02:34:04","AP02EDTM":"2022-02-14 08:34:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":524,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-06","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1622,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8757,"AVALU":"g/L","BASE2":2.95648,"BASE":2.89811,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08078,"PCHG2":-2.73241,"CHG":-0.02241,"PCHG":-0.77317,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-22 04:06:54","ADY":347,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-85","SUBJID":"id-85","SITEID":"PAK-12","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.6978,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-06","TRTSDTM":"2020-09-09 04:06:54","TRTEDTM":"2022-02-14 08:34:04","TRT01SDTM":"2020-09-09 04:06:54","TRT01EDTM":"2021-02-14 02:34:04","TRT02SDTM":"2021-02-14 02:34:04","TRT02EDTM":"2022-02-14 08:34:04","AP01SDTM":"2020-09-09 04:06:54","AP01EDTM":"2021-02-14 02:34:04","AP02SDTM":"2021-02-14 02:34:04","AP02EDTM":"2022-02-14 08:34:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":524,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-06","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7680,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88655,"AVALU":"g/L","BASE2":2.95648,"BASE":2.89811,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06993,"PCHG2":-2.36538,"CHG":-0.01156,"PCHG":-0.39874,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-03 04:06:54","ADY":359,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-12-id-85","SUBJID":"id-85","SITEID":"PAK-12","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-12","INVNAM":"Dr. PAK-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.6978,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-06","TRTSDTM":"2020-09-09 04:06:54","TRTEDTM":"2022-02-14 08:34:04","TRT01SDTM":"2020-09-09 04:06:54","TRT01EDTM":"2021-02-14 02:34:04","TRT02SDTM":"2021-02-14 02:34:04","TRT02EDTM":"2022-02-14 08:34:04","AP01SDTM":"2020-09-09 04:06:54","AP01EDTM":"2021-02-14 02:34:04","AP02SDTM":"2021-02-14 02:34:04","AP02EDTM":"2022-02-14 08:34:04","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":524,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-06","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6959,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83396,"AVALU":"g/L","BASE2":2.95648,"BASE":2.89811,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12253,"PCHG2":-4.14429,"CHG":-0.06415,"PCHG":-2.21349,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-19 04:06:54","ADY":497,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-251","SUBJID":"id-251","SITEID":"PAK-13","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.6604,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-18","TRTSDTM":"2020-03-19 10:52:36","TRTEDTM":"2023-03-20 04:52:36","TRT01SDTM":"2020-03-19 10:52:36","TRT01EDTM":"2022-03-19 22:52:36","TRT02SDTM":"2022-03-19 22:52:36","TRT02EDTM":"2023-03-20 04:52:36","AP01SDTM":"2020-03-19 10:52:36","AP01EDTM":"2022-03-19 22:52:36","AP02SDTM":"2022-03-19 22:52:36","AP02EDTM":"2023-03-20 04:52:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-20","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7323,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.68868,"AVALU":"U/L","BASE2":14.68868,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-22 10:52:36","ADY":248,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-251","SUBJID":"id-251","SITEID":"PAK-13","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.6604,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-18","TRTSDTM":"2020-03-19 10:52:36","TRTEDTM":"2023-03-20 04:52:36","TRT01SDTM":"2020-03-19 10:52:36","TRT01EDTM":"2022-03-19 22:52:36","TRT02SDTM":"2022-03-19 22:52:36","TRT02EDTM":"2023-03-20 04:52:36","AP01SDTM":"2020-03-19 10:52:36","AP01EDTM":"2022-03-19 22:52:36","AP02SDTM":"2022-03-19 22:52:36","AP02EDTM":"2023-03-20 04:52:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-20","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2137,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.59953,"AVALU":"U/L","BASE2":14.68868,"BASE":7.59953,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-7.08915,"PCHG2":-48.2627,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-09 10:52:36","ADY":296,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-251","SUBJID":"id-251","SITEID":"PAK-13","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.6604,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-18","TRTSDTM":"2020-03-19 10:52:36","TRTEDTM":"2023-03-20 04:52:36","TRT01SDTM":"2020-03-19 10:52:36","TRT01EDTM":"2022-03-19 22:52:36","TRT02SDTM":"2022-03-19 22:52:36","TRT02EDTM":"2023-03-20 04:52:36","AP01SDTM":"2020-03-19 10:52:36","AP01EDTM":"2022-03-19 22:52:36","AP02SDTM":"2022-03-19 22:52:36","AP02EDTM":"2023-03-20 04:52:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-20","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2224,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.09369,"AVALU":"U/L","BASE2":14.68868,"BASE":7.59953,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.40501,"PCHG2":23.18118,"CHG":10.49416,"PCHG":138.08971,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-22 10:52:36","ADY":309,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-251","SUBJID":"id-251","SITEID":"PAK-13","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.6604,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-18","TRTSDTM":"2020-03-19 10:52:36","TRTEDTM":"2023-03-20 04:52:36","TRT01SDTM":"2020-03-19 10:52:36","TRT01EDTM":"2022-03-19 22:52:36","TRT02SDTM":"2022-03-19 22:52:36","TRT02EDTM":"2023-03-20 04:52:36","AP01SDTM":"2020-03-19 10:52:36","AP01EDTM":"2022-03-19 22:52:36","AP02SDTM":"2022-03-19 22:52:36","AP02EDTM":"2023-03-20 04:52:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-20","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1754,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":37.88486,"AVALU":"U/L","BASE2":14.68868,"BASE":7.59953,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":23.19618,"PCHG2":157.91873,"CHG":30.28533,"PCHG":398.51606,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-31 10:52:36","ADY":318,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-251","SUBJID":"id-251","SITEID":"PAK-13","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.6604,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-18","TRTSDTM":"2020-03-19 10:52:36","TRTEDTM":"2023-03-20 04:52:36","TRT01SDTM":"2020-03-19 10:52:36","TRT01EDTM":"2022-03-19 22:52:36","TRT02SDTM":"2022-03-19 22:52:36","TRT02EDTM":"2023-03-20 04:52:36","AP01SDTM":"2020-03-19 10:52:36","AP01EDTM":"2022-03-19 22:52:36","AP02SDTM":"2022-03-19 22:52:36","AP02EDTM":"2023-03-20 04:52:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-20","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1135,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.16324,"AVALU":"U/L","BASE2":14.68868,"BASE":7.59953,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.52544,"PCHG2":-44.42495,"CHG":0.56372,"PCHG":7.41777,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-09 10:52:36","ADY":447,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-251","SUBJID":"id-251","SITEID":"PAK-13","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.6604,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-18","TRTSDTM":"2020-03-19 10:52:36","TRTEDTM":"2023-03-20 04:52:36","TRT01SDTM":"2020-03-19 10:52:36","TRT01EDTM":"2022-03-19 22:52:36","TRT02SDTM":"2022-03-19 22:52:36","TRT02EDTM":"2023-03-20 04:52:36","AP01SDTM":"2020-03-19 10:52:36","AP01EDTM":"2022-03-19 22:52:36","AP02SDTM":"2022-03-19 22:52:36","AP02EDTM":"2023-03-20 04:52:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-20","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4958,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.36751,"AVALU":"U/L","BASE2":14.68868,"BASE":7.59953,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.67883,"PCHG2":18.23736,"CHG":9.76798,"PCHG":128.53408,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-01 10:52:36","ADY":653,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-251","SUBJID":"id-251","SITEID":"PAK-13","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.6604,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-18","TRTSDTM":"2020-03-19 10:52:36","TRTEDTM":"2023-03-20 04:52:36","TRT01SDTM":"2020-03-19 10:52:36","TRT01EDTM":"2022-03-19 22:52:36","TRT02SDTM":"2022-03-19 22:52:36","TRT02EDTM":"2023-03-20 04:52:36","AP01SDTM":"2020-03-19 10:52:36","AP01EDTM":"2022-03-19 22:52:36","AP02SDTM":"2022-03-19 22:52:36","AP02EDTM":"2023-03-20 04:52:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-20","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2122,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.039,"AVALU":"U/L","BASE2":14.68868,"BASE":7.59953,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.35032,"PCHG2":111.31237,"CHG":23.43947,"PCHG":308.43334,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-12 10:52:36","ADY":815,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-251","SUBJID":"id-251","SITEID":"PAK-13","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.6604,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-18","TRTSDTM":"2020-03-19 10:52:36","TRTEDTM":"2023-03-20 04:52:36","TRT01SDTM":"2020-03-19 10:52:36","TRT01EDTM":"2022-03-19 22:52:36","TRT02SDTM":"2022-03-19 22:52:36","TRT02EDTM":"2023-03-20 04:52:36","AP01SDTM":"2020-03-19 10:52:36","AP01EDTM":"2022-03-19 22:52:36","AP02SDTM":"2022-03-19 22:52:36","AP02EDTM":"2023-03-20 04:52:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-20","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6864,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.2524,"AVALU":"mg/L","BASE2":8.2524,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-3","ADTM":"2020-11-22 10:52:36","ADY":248,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-251","SUBJID":"id-251","SITEID":"PAK-13","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.6604,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-18","TRTSDTM":"2020-03-19 10:52:36","TRTEDTM":"2023-03-20 04:52:36","TRT01SDTM":"2020-03-19 10:52:36","TRT01EDTM":"2022-03-19 22:52:36","TRT02SDTM":"2022-03-19 22:52:36","TRT02EDTM":"2023-03-20 04:52:36","AP01SDTM":"2020-03-19 10:52:36","AP01EDTM":"2022-03-19 22:52:36","AP02SDTM":"2022-03-19 22:52:36","AP02EDTM":"2023-03-20 04:52:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-20","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7440,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.8075,"AVALU":"mg/L","BASE2":8.2524,"BASE":7.8075,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.44491,"PCHG2":-5.39128,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2021-01-09 10:52:36","ADY":296,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-251","SUBJID":"id-251","SITEID":"PAK-13","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.6604,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-18","TRTSDTM":"2020-03-19 10:52:36","TRTEDTM":"2023-03-20 04:52:36","TRT01SDTM":"2020-03-19 10:52:36","TRT01EDTM":"2022-03-19 22:52:36","TRT02SDTM":"2022-03-19 22:52:36","TRT02EDTM":"2023-03-20 04:52:36","AP01SDTM":"2020-03-19 10:52:36","AP01EDTM":"2022-03-19 22:52:36","AP02SDTM":"2022-03-19 22:52:36","AP02EDTM":"2023-03-20 04:52:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-20","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4872,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.06552,"AVALU":"mg/L","BASE2":8.2524,"BASE":7.8075,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.81312,"PCHG2":9.85308,"CHG":1.25803,"PCHG":16.11306,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-01-22 10:52:36","ADY":309,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-251","SUBJID":"id-251","SITEID":"PAK-13","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.6604,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-18","TRTSDTM":"2020-03-19 10:52:36","TRTEDTM":"2023-03-20 04:52:36","TRT01SDTM":"2020-03-19 10:52:36","TRT01EDTM":"2022-03-19 22:52:36","TRT02SDTM":"2022-03-19 22:52:36","TRT02EDTM":"2023-03-20 04:52:36","AP01SDTM":"2020-03-19 10:52:36","AP01EDTM":"2022-03-19 22:52:36","AP02SDTM":"2022-03-19 22:52:36","AP02EDTM":"2023-03-20 04:52:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-20","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1098,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.76218,"AVALU":"mg/L","BASE2":8.2524,"BASE":7.8075,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.49022,"PCHG2":-5.94034,"CHG":-0.04531,"PCHG":-0.58035,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-3","ADTM":"2021-01-31 10:52:36","ADY":318,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-251","SUBJID":"id-251","SITEID":"PAK-13","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.6604,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-18","TRTSDTM":"2020-03-19 10:52:36","TRTEDTM":"2023-03-20 04:52:36","TRT01SDTM":"2020-03-19 10:52:36","TRT01EDTM":"2022-03-19 22:52:36","TRT02SDTM":"2022-03-19 22:52:36","TRT02EDTM":"2023-03-20 04:52:36","AP01SDTM":"2020-03-19 10:52:36","AP01EDTM":"2022-03-19 22:52:36","AP02SDTM":"2022-03-19 22:52:36","AP02EDTM":"2023-03-20 04:52:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-20","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5068,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.28541,"AVALU":"mg/L","BASE2":8.2524,"BASE":7.8075,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.03301,"PCHG2":24.63536,"CHG":2.47792,"PCHG":31.7377,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"4","BTOXGR":"-3","ADTM":"2021-06-09 10:52:36","ADY":447,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-251","SUBJID":"id-251","SITEID":"PAK-13","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.6604,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-18","TRTSDTM":"2020-03-19 10:52:36","TRTEDTM":"2023-03-20 04:52:36","TRT01SDTM":"2020-03-19 10:52:36","TRT01EDTM":"2022-03-19 22:52:36","TRT02SDTM":"2022-03-19 22:52:36","TRT02EDTM":"2023-03-20 04:52:36","AP01SDTM":"2020-03-19 10:52:36","AP01EDTM":"2022-03-19 22:52:36","AP02SDTM":"2022-03-19 22:52:36","AP02EDTM":"2023-03-20 04:52:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-20","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4028,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.55458,"AVALU":"mg/L","BASE2":8.2524,"BASE":7.8075,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.69782,"PCHG2":-8.456,"CHG":-0.25291,"PCHG":-3.23936,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2022-01-01 10:52:36","ADY":653,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-251","SUBJID":"id-251","SITEID":"PAK-13","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.6604,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-18","TRTSDTM":"2020-03-19 10:52:36","TRTEDTM":"2023-03-20 04:52:36","TRT01SDTM":"2020-03-19 10:52:36","TRT01EDTM":"2022-03-19 22:52:36","TRT02SDTM":"2022-03-19 22:52:36","TRT02EDTM":"2023-03-20 04:52:36","AP01SDTM":"2020-03-19 10:52:36","AP01EDTM":"2022-03-19 22:52:36","AP02SDTM":"2022-03-19 22:52:36","AP02EDTM":"2023-03-20 04:52:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-20","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":771,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.60496,"AVALU":"mg/L","BASE2":8.2524,"BASE":7.8075,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.35255,"PCHG2":28.50747,"CHG":2.79746,"PCHG":35.83047,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"1","BTOXGR":"-3","ADTM":"2022-06-12 10:52:36","ADY":815,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-251","SUBJID":"id-251","SITEID":"PAK-13","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.6604,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-18","TRTSDTM":"2020-03-19 10:52:36","TRTEDTM":"2023-03-20 04:52:36","TRT01SDTM":"2020-03-19 10:52:36","TRT01EDTM":"2022-03-19 22:52:36","TRT02SDTM":"2022-03-19 22:52:36","TRT02EDTM":"2023-03-20 04:52:36","AP01SDTM":"2020-03-19 10:52:36","AP01EDTM":"2022-03-19 22:52:36","AP02SDTM":"2022-03-19 22:52:36","AP02EDTM":"2023-03-20 04:52:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-20","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":814,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02473,"AVALU":"g/L","BASE2":3.02473,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-11-22 10:52:36","ADY":248,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-251","SUBJID":"id-251","SITEID":"PAK-13","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.6604,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-18","TRTSDTM":"2020-03-19 10:52:36","TRTEDTM":"2023-03-20 04:52:36","TRT01SDTM":"2020-03-19 10:52:36","TRT01EDTM":"2022-03-19 22:52:36","TRT02SDTM":"2022-03-19 22:52:36","TRT02EDTM":"2023-03-20 04:52:36","AP01SDTM":"2020-03-19 10:52:36","AP01EDTM":"2022-03-19 22:52:36","AP02SDTM":"2022-03-19 22:52:36","AP02EDTM":"2023-03-20 04:52:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-20","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4470,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76027,"AVALU":"g/L","BASE2":3.02473,"BASE":2.76027,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.26446,"PCHG2":-8.74317,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-09 10:52:36","ADY":296,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-251","SUBJID":"id-251","SITEID":"PAK-13","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.6604,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-18","TRTSDTM":"2020-03-19 10:52:36","TRTEDTM":"2023-03-20 04:52:36","TRT01SDTM":"2020-03-19 10:52:36","TRT01EDTM":"2022-03-19 22:52:36","TRT02SDTM":"2022-03-19 22:52:36","TRT02EDTM":"2023-03-20 04:52:36","AP01SDTM":"2020-03-19 10:52:36","AP01EDTM":"2022-03-19 22:52:36","AP02SDTM":"2022-03-19 22:52:36","AP02EDTM":"2023-03-20 04:52:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-20","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2592,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00636,"AVALU":"g/L","BASE2":3.02473,"BASE":2.76027,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01837,"PCHG2":-0.60741,"CHG":0.24608,"PCHG":8.91523,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-01-22 10:52:36","ADY":309,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-251","SUBJID":"id-251","SITEID":"PAK-13","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.6604,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-18","TRTSDTM":"2020-03-19 10:52:36","TRTEDTM":"2023-03-20 04:52:36","TRT01SDTM":"2020-03-19 10:52:36","TRT01EDTM":"2022-03-19 22:52:36","TRT02SDTM":"2022-03-19 22:52:36","TRT02EDTM":"2023-03-20 04:52:36","AP01SDTM":"2020-03-19 10:52:36","AP01EDTM":"2022-03-19 22:52:36","AP02SDTM":"2022-03-19 22:52:36","AP02EDTM":"2023-03-20 04:52:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-20","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6814,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.73855,"AVALU":"g/L","BASE2":3.02473,"BASE":2.76027,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.28618,"PCHG2":-9.46118,"CHG":-0.02172,"PCHG":-0.78681,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-31 10:52:36","ADY":318,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-251","SUBJID":"id-251","SITEID":"PAK-13","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.6604,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-18","TRTSDTM":"2020-03-19 10:52:36","TRTEDTM":"2023-03-20 04:52:36","TRT01SDTM":"2020-03-19 10:52:36","TRT01EDTM":"2022-03-19 22:52:36","TRT02SDTM":"2022-03-19 22:52:36","TRT02EDTM":"2023-03-20 04:52:36","AP01SDTM":"2020-03-19 10:52:36","AP01EDTM":"2022-03-19 22:52:36","AP02SDTM":"2022-03-19 22:52:36","AP02EDTM":"2023-03-20 04:52:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-20","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5574,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80962,"AVALU":"g/L","BASE2":3.02473,"BASE":2.76027,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.2151,"PCHG2":-7.11152,"CHG":0.04935,"PCHG":1.78798,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-09 10:52:36","ADY":447,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-251","SUBJID":"id-251","SITEID":"PAK-13","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.6604,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-18","TRTSDTM":"2020-03-19 10:52:36","TRTEDTM":"2023-03-20 04:52:36","TRT01SDTM":"2020-03-19 10:52:36","TRT01EDTM":"2022-03-19 22:52:36","TRT02SDTM":"2022-03-19 22:52:36","TRT02EDTM":"2023-03-20 04:52:36","AP01SDTM":"2020-03-19 10:52:36","AP01EDTM":"2022-03-19 22:52:36","AP02SDTM":"2022-03-19 22:52:36","AP02EDTM":"2023-03-20 04:52:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-20","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7735,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.12651,"AVALU":"g/L","BASE2":3.02473,"BASE":2.76027,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10178,"PCHG2":3.3649,"CHG":0.36624,"PCHG":13.26812,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-01-01 10:52:36","ADY":653,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-251","SUBJID":"id-251","SITEID":"PAK-13","AGE":32,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.6604,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-18","TRTSDTM":"2020-03-19 10:52:36","TRTEDTM":"2023-03-20 04:52:36","TRT01SDTM":"2020-03-19 10:52:36","TRT01EDTM":"2022-03-19 22:52:36","TRT02SDTM":"2022-03-19 22:52:36","TRT02EDTM":"2023-03-20 04:52:36","AP01SDTM":"2020-03-19 10:52:36","AP01EDTM":"2022-03-19 22:52:36","AP02SDTM":"2022-03-19 22:52:36","AP02EDTM":"2023-03-20 04:52:36","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-20","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6067,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75772,"AVALU":"g/L","BASE2":3.02473,"BASE":2.76027,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.26701,"PCHG2":-8.82765,"CHG":-0.00256,"PCHG":-0.09258,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-12 10:52:36","ADY":815,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-350","SUBJID":"id-350","SITEID":"PAK-13","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.71377,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-21","TRTSDTM":"2020-11-24 07:06:07","TRTEDTM":"2023-11-25 01:06:07","TRT01SDTM":"2020-11-24 07:06:07","TRT01EDTM":"2022-11-24 19:06:07","TRT02SDTM":"2022-11-24 19:06:07","TRT02EDTM":"2023-11-25 01:06:07","AP01SDTM":"2020-11-24 07:06:07","AP01EDTM":"2022-11-24 19:06:07","AP02SDTM":"2022-11-24 19:06:07","AP02EDTM":"2023-11-25 01:06:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-25","EOSDY":1096,"LSTALVDT":"2023-12-06","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5172,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.44357,"AVALU":"U/L","BASE2":16.44357,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-05 07:06:07","ADY":101,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-350","SUBJID":"id-350","SITEID":"PAK-13","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.71377,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-21","TRTSDTM":"2020-11-24 07:06:07","TRTEDTM":"2023-11-25 01:06:07","TRT01SDTM":"2020-11-24 07:06:07","TRT01EDTM":"2022-11-24 19:06:07","TRT02SDTM":"2022-11-24 19:06:07","TRT02EDTM":"2023-11-25 01:06:07","AP01SDTM":"2020-11-24 07:06:07","AP01EDTM":"2022-11-24 19:06:07","AP02SDTM":"2022-11-24 19:06:07","AP02EDTM":"2023-11-25 01:06:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-25","EOSDY":1096,"LSTALVDT":"2023-12-06","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4404,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.02433,"AVALU":"U/L","BASE2":16.44357,"BASE":19.02433,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.58075,"PCHG2":15.6946,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-05 07:06:07","ADY":223,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-350","SUBJID":"id-350","SITEID":"PAK-13","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.71377,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-21","TRTSDTM":"2020-11-24 07:06:07","TRTEDTM":"2023-11-25 01:06:07","TRT01SDTM":"2020-11-24 07:06:07","TRT01EDTM":"2022-11-24 19:06:07","TRT02SDTM":"2022-11-24 19:06:07","TRT02EDTM":"2023-11-25 01:06:07","AP01SDTM":"2020-11-24 07:06:07","AP01EDTM":"2022-11-24 19:06:07","AP02SDTM":"2022-11-24 19:06:07","AP02EDTM":"2023-11-25 01:06:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-25","EOSDY":1096,"LSTALVDT":"2023-12-06","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2663,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.03712,"AVALU":"U/L","BASE2":16.44357,"BASE":19.02433,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.40646,"PCHG2":-63.28587,"CHG":-12.98721,"PCHG":-68.26634,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-10-14 07:06:07","ADY":324,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-350","SUBJID":"id-350","SITEID":"PAK-13","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.71377,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-21","TRTSDTM":"2020-11-24 07:06:07","TRTEDTM":"2023-11-25 01:06:07","TRT01SDTM":"2020-11-24 07:06:07","TRT01EDTM":"2022-11-24 19:06:07","TRT02SDTM":"2022-11-24 19:06:07","TRT02EDTM":"2023-11-25 01:06:07","AP01SDTM":"2020-11-24 07:06:07","AP01EDTM":"2022-11-24 19:06:07","AP02SDTM":"2022-11-24 19:06:07","AP02EDTM":"2023-11-25 01:06:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-25","EOSDY":1096,"LSTALVDT":"2023-12-06","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3465,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.26169,"AVALU":"U/L","BASE2":16.44357,"BASE":19.02433,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.81811,"PCHG2":59.7079,"CHG":7.23736,"PCHG":38.04265,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-08 07:06:07","ADY":441,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-350","SUBJID":"id-350","SITEID":"PAK-13","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.71377,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-21","TRTSDTM":"2020-11-24 07:06:07","TRTEDTM":"2023-11-25 01:06:07","TRT01SDTM":"2020-11-24 07:06:07","TRT01EDTM":"2022-11-24 19:06:07","TRT02SDTM":"2022-11-24 19:06:07","TRT02EDTM":"2023-11-25 01:06:07","AP01SDTM":"2020-11-24 07:06:07","AP01EDTM":"2022-11-24 19:06:07","AP02SDTM":"2022-11-24 19:06:07","AP02EDTM":"2023-11-25 01:06:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-25","EOSDY":1096,"LSTALVDT":"2023-12-06","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7874,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.933,"AVALU":"U/L","BASE2":16.44357,"BASE":19.02433,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.48943,"PCHG2":69.87183,"CHG":8.90867,"PCHG":46.82779,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-14 07:06:07","ADY":506,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-350","SUBJID":"id-350","SITEID":"PAK-13","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.71377,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-21","TRTSDTM":"2020-11-24 07:06:07","TRTEDTM":"2023-11-25 01:06:07","TRT01SDTM":"2020-11-24 07:06:07","TRT01EDTM":"2022-11-24 19:06:07","TRT02SDTM":"2022-11-24 19:06:07","TRT02EDTM":"2023-11-25 01:06:07","AP01SDTM":"2020-11-24 07:06:07","AP01EDTM":"2022-11-24 19:06:07","AP02SDTM":"2022-11-24 19:06:07","AP02EDTM":"2023-11-25 01:06:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-25","EOSDY":1096,"LSTALVDT":"2023-12-06","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6620,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.03992,"AVALU":"U/L","BASE2":16.44357,"BASE":19.02433,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.40365,"PCHG2":-32.86178,"CHG":-7.9844,"PCHG":-41.96944,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-02 07:06:07","ADY":647,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-350","SUBJID":"id-350","SITEID":"PAK-13","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.71377,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-21","TRTSDTM":"2020-11-24 07:06:07","TRTEDTM":"2023-11-25 01:06:07","TRT01SDTM":"2020-11-24 07:06:07","TRT01EDTM":"2022-11-24 19:06:07","TRT02SDTM":"2022-11-24 19:06:07","TRT02EDTM":"2023-11-25 01:06:07","AP01SDTM":"2020-11-24 07:06:07","AP01EDTM":"2022-11-24 19:06:07","AP02SDTM":"2022-11-24 19:06:07","AP02EDTM":"2023-11-25 01:06:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-25","EOSDY":1096,"LSTALVDT":"2023-12-06","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1697,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.08508,"AVALU":"U/L","BASE2":16.44357,"BASE":19.02433,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.64151,"PCHG2":64.71529,"CHG":8.06075,"PCHG":42.37077,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-10-17 07:06:07","ADY":1057,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-350","SUBJID":"id-350","SITEID":"PAK-13","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.71377,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-21","TRTSDTM":"2020-11-24 07:06:07","TRTEDTM":"2023-11-25 01:06:07","TRT01SDTM":"2020-11-24 07:06:07","TRT01EDTM":"2022-11-24 19:06:07","TRT02SDTM":"2022-11-24 19:06:07","TRT02EDTM":"2023-11-25 01:06:07","AP01SDTM":"2020-11-24 07:06:07","AP01EDTM":"2022-11-24 19:06:07","AP02SDTM":"2022-11-24 19:06:07","AP02EDTM":"2023-11-25 01:06:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-25","EOSDY":1096,"LSTALVDT":"2023-12-06","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2516,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.40199,"AVALU":"mg/L","BASE2":9.40199,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-05 07:06:07","ADY":101,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-350","SUBJID":"id-350","SITEID":"PAK-13","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.71377,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-21","TRTSDTM":"2020-11-24 07:06:07","TRTEDTM":"2023-11-25 01:06:07","TRT01SDTM":"2020-11-24 07:06:07","TRT01EDTM":"2022-11-24 19:06:07","TRT02SDTM":"2022-11-24 19:06:07","TRT02EDTM":"2023-11-25 01:06:07","AP01SDTM":"2020-11-24 07:06:07","AP01EDTM":"2022-11-24 19:06:07","AP02SDTM":"2022-11-24 19:06:07","AP02EDTM":"2023-11-25 01:06:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-25","EOSDY":1096,"LSTALVDT":"2023-12-06","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6595,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.79259,"AVALU":"mg/L","BASE2":9.40199,"BASE":8.79259,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.6094,"PCHG2":-6.48162,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-05 07:06:07","ADY":223,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-350","SUBJID":"id-350","SITEID":"PAK-13","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.71377,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-21","TRTSDTM":"2020-11-24 07:06:07","TRTEDTM":"2023-11-25 01:06:07","TRT01SDTM":"2020-11-24 07:06:07","TRT01EDTM":"2022-11-24 19:06:07","TRT02SDTM":"2022-11-24 19:06:07","TRT02EDTM":"2023-11-25 01:06:07","AP01SDTM":"2020-11-24 07:06:07","AP01EDTM":"2022-11-24 19:06:07","AP02SDTM":"2022-11-24 19:06:07","AP02EDTM":"2023-11-25 01:06:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-25","EOSDY":1096,"LSTALVDT":"2023-12-06","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2033,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.76085,"AVALU":"mg/L","BASE2":9.40199,"BASE":8.79259,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.35886,"PCHG2":3.81686,"CHG":0.96826,"PCHG":11.01225,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-14 07:06:07","ADY":324,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-350","SUBJID":"id-350","SITEID":"PAK-13","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.71377,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-21","TRTSDTM":"2020-11-24 07:06:07","TRTEDTM":"2023-11-25 01:06:07","TRT01SDTM":"2020-11-24 07:06:07","TRT01EDTM":"2022-11-24 19:06:07","TRT02SDTM":"2022-11-24 19:06:07","TRT02EDTM":"2023-11-25 01:06:07","AP01SDTM":"2020-11-24 07:06:07","AP01EDTM":"2022-11-24 19:06:07","AP02SDTM":"2022-11-24 19:06:07","AP02EDTM":"2023-11-25 01:06:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-25","EOSDY":1096,"LSTALVDT":"2023-12-06","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5143,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.37223,"AVALU":"mg/L","BASE2":9.40199,"BASE":8.79259,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.02976,"PCHG2":-10.95256,"CHG":-0.42036,"PCHG":-4.78082,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-08 07:06:07","ADY":441,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-350","SUBJID":"id-350","SITEID":"PAK-13","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.71377,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-21","TRTSDTM":"2020-11-24 07:06:07","TRTEDTM":"2023-11-25 01:06:07","TRT01SDTM":"2020-11-24 07:06:07","TRT01EDTM":"2022-11-24 19:06:07","TRT02SDTM":"2022-11-24 19:06:07","TRT02EDTM":"2023-11-25 01:06:07","AP01SDTM":"2020-11-24 07:06:07","AP01EDTM":"2022-11-24 19:06:07","AP02SDTM":"2022-11-24 19:06:07","AP02EDTM":"2023-11-25 01:06:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-25","EOSDY":1096,"LSTALVDT":"2023-12-06","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1698,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.81048,"AVALU":"mg/L","BASE2":9.40199,"BASE":8.79259,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.59151,"PCHG2":-6.29137,"CHG":0.01789,"PCHG":0.20343,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-14 07:06:07","ADY":506,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-350","SUBJID":"id-350","SITEID":"PAK-13","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.71377,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-21","TRTSDTM":"2020-11-24 07:06:07","TRTEDTM":"2023-11-25 01:06:07","TRT01SDTM":"2020-11-24 07:06:07","TRT01EDTM":"2022-11-24 19:06:07","TRT02SDTM":"2022-11-24 19:06:07","TRT02EDTM":"2023-11-25 01:06:07","AP01SDTM":"2020-11-24 07:06:07","AP01EDTM":"2022-11-24 19:06:07","AP02SDTM":"2022-11-24 19:06:07","AP02EDTM":"2023-11-25 01:06:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-25","EOSDY":1096,"LSTALVDT":"2023-12-06","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4764,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.39651,"AVALU":"mg/L","BASE2":9.40199,"BASE":8.79259,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00548,"PCHG2":-0.05833,"CHG":0.60392,"PCHG":6.86848,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-02 07:06:07","ADY":647,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-350","SUBJID":"id-350","SITEID":"PAK-13","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.71377,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-21","TRTSDTM":"2020-11-24 07:06:07","TRTEDTM":"2023-11-25 01:06:07","TRT01SDTM":"2020-11-24 07:06:07","TRT01EDTM":"2022-11-24 19:06:07","TRT02SDTM":"2022-11-24 19:06:07","TRT02EDTM":"2023-11-25 01:06:07","AP01SDTM":"2020-11-24 07:06:07","AP01EDTM":"2022-11-24 19:06:07","AP02SDTM":"2022-11-24 19:06:07","AP02EDTM":"2023-11-25 01:06:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-25","EOSDY":1096,"LSTALVDT":"2023-12-06","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6025,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.01287,"AVALU":"mg/L","BASE2":9.40199,"BASE":8.79259,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.38913,"PCHG2":-4.13877,"CHG":0.22027,"PCHG":2.50522,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-10-17 07:06:07","ADY":1057,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-350","SUBJID":"id-350","SITEID":"PAK-13","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.71377,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-21","TRTSDTM":"2020-11-24 07:06:07","TRTEDTM":"2023-11-25 01:06:07","TRT01SDTM":"2020-11-24 07:06:07","TRT01EDTM":"2022-11-24 19:06:07","TRT02SDTM":"2022-11-24 19:06:07","TRT02EDTM":"2023-11-25 01:06:07","AP01SDTM":"2020-11-24 07:06:07","AP01EDTM":"2022-11-24 19:06:07","AP02SDTM":"2022-11-24 19:06:07","AP02EDTM":"2023-11-25 01:06:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-25","EOSDY":1096,"LSTALVDT":"2023-12-06","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5089,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00861,"AVALU":"g/L","BASE2":3.00861,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-03-05 07:06:07","ADY":101,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-350","SUBJID":"id-350","SITEID":"PAK-13","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.71377,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-21","TRTSDTM":"2020-11-24 07:06:07","TRTEDTM":"2023-11-25 01:06:07","TRT01SDTM":"2020-11-24 07:06:07","TRT01EDTM":"2022-11-24 19:06:07","TRT02SDTM":"2022-11-24 19:06:07","TRT02EDTM":"2023-11-25 01:06:07","AP01SDTM":"2020-11-24 07:06:07","AP01EDTM":"2022-11-24 19:06:07","AP02SDTM":"2022-11-24 19:06:07","AP02EDTM":"2023-11-25 01:06:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-25","EOSDY":1096,"LSTALVDT":"2023-12-06","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4838,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7891,"AVALU":"g/L","BASE2":3.00861,"BASE":2.7891,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.21951,"PCHG2":-7.29604,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-05 07:06:07","ADY":223,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-350","SUBJID":"id-350","SITEID":"PAK-13","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.71377,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-21","TRTSDTM":"2020-11-24 07:06:07","TRTEDTM":"2023-11-25 01:06:07","TRT01SDTM":"2020-11-24 07:06:07","TRT01EDTM":"2022-11-24 19:06:07","TRT02SDTM":"2022-11-24 19:06:07","TRT02EDTM":"2023-11-25 01:06:07","AP01SDTM":"2020-11-24 07:06:07","AP01EDTM":"2022-11-24 19:06:07","AP02SDTM":"2022-11-24 19:06:07","AP02EDTM":"2023-11-25 01:06:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-25","EOSDY":1096,"LSTALVDT":"2023-12-06","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4272,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99295,"AVALU":"g/L","BASE2":3.00861,"BASE":2.7891,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01566,"PCHG2":-0.52035,"CHG":0.20385,"PCHG":7.30895,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-14 07:06:07","ADY":324,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-350","SUBJID":"id-350","SITEID":"PAK-13","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.71377,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-21","TRTSDTM":"2020-11-24 07:06:07","TRTEDTM":"2023-11-25 01:06:07","TRT01SDTM":"2020-11-24 07:06:07","TRT01EDTM":"2022-11-24 19:06:07","TRT02SDTM":"2022-11-24 19:06:07","TRT02EDTM":"2023-11-25 01:06:07","AP01SDTM":"2020-11-24 07:06:07","AP01EDTM":"2022-11-24 19:06:07","AP02SDTM":"2022-11-24 19:06:07","AP02EDTM":"2023-11-25 01:06:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-25","EOSDY":1096,"LSTALVDT":"2023-12-06","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6264,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83938,"AVALU":"g/L","BASE2":3.00861,"BASE":2.7891,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16923,"PCHG2":-5.6249,"CHG":0.05028,"PCHG":1.80266,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-08 07:06:07","ADY":441,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-350","SUBJID":"id-350","SITEID":"PAK-13","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.71377,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-21","TRTSDTM":"2020-11-24 07:06:07","TRTEDTM":"2023-11-25 01:06:07","TRT01SDTM":"2020-11-24 07:06:07","TRT01EDTM":"2022-11-24 19:06:07","TRT02SDTM":"2022-11-24 19:06:07","TRT02EDTM":"2023-11-25 01:06:07","AP01SDTM":"2020-11-24 07:06:07","AP01EDTM":"2022-11-24 19:06:07","AP02SDTM":"2022-11-24 19:06:07","AP02EDTM":"2023-11-25 01:06:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-25","EOSDY":1096,"LSTALVDT":"2023-12-06","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6822,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93176,"AVALU":"g/L","BASE2":3.00861,"BASE":2.7891,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07685,"PCHG2":-2.5543,"CHG":0.14266,"PCHG":5.11493,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-14 07:06:07","ADY":506,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-350","SUBJID":"id-350","SITEID":"PAK-13","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.71377,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-21","TRTSDTM":"2020-11-24 07:06:07","TRTEDTM":"2023-11-25 01:06:07","TRT01SDTM":"2020-11-24 07:06:07","TRT01EDTM":"2022-11-24 19:06:07","TRT02SDTM":"2022-11-24 19:06:07","TRT02EDTM":"2023-11-25 01:06:07","AP01SDTM":"2020-11-24 07:06:07","AP01EDTM":"2022-11-24 19:06:07","AP02SDTM":"2022-11-24 19:06:07","AP02EDTM":"2023-11-25 01:06:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-25","EOSDY":1096,"LSTALVDT":"2023-12-06","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5496,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78364,"AVALU":"g/L","BASE2":3.00861,"BASE":2.7891,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.22497,"PCHG2":-7.47742,"CHG":-0.00546,"PCHG":-0.19566,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-02 07:06:07","ADY":647,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-13-id-350","SUBJID":"id-350","SITEID":"PAK-13","AGE":39,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-13","INVNAM":"Dr. PAK-13 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.71377,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-21","TRTSDTM":"2020-11-24 07:06:07","TRTEDTM":"2023-11-25 01:06:07","TRT01SDTM":"2020-11-24 07:06:07","TRT01EDTM":"2022-11-24 19:06:07","TRT02SDTM":"2022-11-24 19:06:07","TRT02EDTM":"2023-11-25 01:06:07","AP01SDTM":"2020-11-24 07:06:07","AP01EDTM":"2022-11-24 19:06:07","AP02SDTM":"2022-11-24 19:06:07","AP02EDTM":"2023-11-25 01:06:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-25","EOSDY":1096,"LSTALVDT":"2023-12-06","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2312,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93821,"AVALU":"g/L","BASE2":3.00861,"BASE":2.7891,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0704,"PCHG2":-2.34008,"CHG":0.14911,"PCHG":5.34601,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-10-17 07:06:07","ADY":1057,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-14-id-117","SUBJID":"id-117","SITEID":"PAK-14","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-14","INVNAM":"Dr. PAK-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.26523,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-15 04:23:49","TRTEDTM":"2022-02-20 01:27:23","TRT01SDTM":"2019-07-15 04:23:49","TRT01EDTM":"2021-02-19 19:27:23","TRT02SDTM":"2021-02-19 19:27:23","TRT02EDTM":"2022-02-20 01:27:23","AP01SDTM":"2019-07-15 04:23:49","AP01EDTM":"2021-02-19 19:27:23","AP02SDTM":"2021-02-19 19:27:23","AP02EDTM":"2022-02-20 01:27:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":951,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-21","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2398,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.88792,"AVALU":"U/L","BASE2":19.88792,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-20 04:23:49","ADY":97,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-14-id-117","SUBJID":"id-117","SITEID":"PAK-14","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-14","INVNAM":"Dr. PAK-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.26523,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-15 04:23:49","TRTEDTM":"2022-02-20 01:27:23","TRT01SDTM":"2019-07-15 04:23:49","TRT01EDTM":"2021-02-19 19:27:23","TRT02SDTM":"2021-02-19 19:27:23","TRT02EDTM":"2022-02-20 01:27:23","AP01SDTM":"2019-07-15 04:23:49","AP01EDTM":"2021-02-19 19:27:23","AP02SDTM":"2021-02-19 19:27:23","AP02EDTM":"2022-02-20 01:27:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":951,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-21","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7934,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.94332,"AVALU":"U/L","BASE2":19.88792,"BASE":17.94332,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.9446,"PCHG2":-9.7778,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-28 04:23:49","ADY":136,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-14-id-117","SUBJID":"id-117","SITEID":"PAK-14","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-14","INVNAM":"Dr. PAK-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.26523,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-15 04:23:49","TRTEDTM":"2022-02-20 01:27:23","TRT01SDTM":"2019-07-15 04:23:49","TRT01EDTM":"2021-02-19 19:27:23","TRT02SDTM":"2021-02-19 19:27:23","TRT02EDTM":"2022-02-20 01:27:23","AP01SDTM":"2019-07-15 04:23:49","AP01EDTM":"2021-02-19 19:27:23","AP02SDTM":"2021-02-19 19:27:23","AP02EDTM":"2022-02-20 01:27:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":951,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-21","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1937,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.89609,"AVALU":"U/L","BASE2":19.88792,"BASE":17.94332,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00817,"PCHG2":0.04107,"CHG":1.95277,"PCHG":10.88299,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-25 04:23:49","ADY":225,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-14-id-117","SUBJID":"id-117","SITEID":"PAK-14","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-14","INVNAM":"Dr. PAK-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.26523,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-15 04:23:49","TRTEDTM":"2022-02-20 01:27:23","TRT01SDTM":"2019-07-15 04:23:49","TRT01EDTM":"2021-02-19 19:27:23","TRT02SDTM":"2021-02-19 19:27:23","TRT02EDTM":"2022-02-20 01:27:23","AP01SDTM":"2019-07-15 04:23:49","AP01EDTM":"2021-02-19 19:27:23","AP02SDTM":"2021-02-19 19:27:23","AP02EDTM":"2022-02-20 01:27:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":951,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-21","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":892,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.08614,"AVALU":"U/L","BASE2":19.88792,"BASE":17.94332,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.19821,"PCHG2":36.19389,"CHG":9.14281,"PCHG":50.95386,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-08 04:23:49","ADY":329,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-14-id-117","SUBJID":"id-117","SITEID":"PAK-14","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-14","INVNAM":"Dr. PAK-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.26523,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-15 04:23:49","TRTEDTM":"2022-02-20 01:27:23","TRT01SDTM":"2019-07-15 04:23:49","TRT01EDTM":"2021-02-19 19:27:23","TRT02SDTM":"2021-02-19 19:27:23","TRT02EDTM":"2022-02-20 01:27:23","AP01SDTM":"2019-07-15 04:23:49","AP01EDTM":"2021-02-19 19:27:23","AP02SDTM":"2021-02-19 19:27:23","AP02EDTM":"2022-02-20 01:27:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":951,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-21","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7160,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.2069,"AVALU":"U/L","BASE2":19.88792,"BASE":17.94332,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.31898,"PCHG2":36.80113,"CHG":9.26358,"PCHG":51.62691,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-14 04:23:49","ADY":396,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-14-id-117","SUBJID":"id-117","SITEID":"PAK-14","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-14","INVNAM":"Dr. PAK-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.26523,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-15 04:23:49","TRTEDTM":"2022-02-20 01:27:23","TRT01SDTM":"2019-07-15 04:23:49","TRT01EDTM":"2021-02-19 19:27:23","TRT02SDTM":"2021-02-19 19:27:23","TRT02EDTM":"2022-02-20 01:27:23","AP01SDTM":"2019-07-15 04:23:49","AP01EDTM":"2021-02-19 19:27:23","AP02SDTM":"2021-02-19 19:27:23","AP02EDTM":"2022-02-20 01:27:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":951,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-21","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6527,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.80942,"AVALU":"U/L","BASE2":19.88792,"BASE":17.94332,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.0785,"PCHG2":-55.70466,"CHG":-9.1339,"PCHG":-50.90417,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-13 04:23:49","ADY":548,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-14-id-117","SUBJID":"id-117","SITEID":"PAK-14","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-14","INVNAM":"Dr. PAK-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.26523,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-15 04:23:49","TRTEDTM":"2022-02-20 01:27:23","TRT01SDTM":"2019-07-15 04:23:49","TRT01EDTM":"2021-02-19 19:27:23","TRT02SDTM":"2021-02-19 19:27:23","TRT02EDTM":"2022-02-20 01:27:23","AP01SDTM":"2019-07-15 04:23:49","AP01EDTM":"2021-02-19 19:27:23","AP02SDTM":"2021-02-19 19:27:23","AP02EDTM":"2022-02-20 01:27:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":951,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-21","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":473,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.1719,"AVALU":"U/L","BASE2":19.88792,"BASE":17.94332,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.28397,"PCHG2":26.56876,"CHG":7.22858,"PCHG":40.28561,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-14 04:23:49","ADY":914,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-14-id-117","SUBJID":"id-117","SITEID":"PAK-14","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-14","INVNAM":"Dr. PAK-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.26523,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-15 04:23:49","TRTEDTM":"2022-02-20 01:27:23","TRT01SDTM":"2019-07-15 04:23:49","TRT01EDTM":"2021-02-19 19:27:23","TRT02SDTM":"2021-02-19 19:27:23","TRT02EDTM":"2022-02-20 01:27:23","AP01SDTM":"2019-07-15 04:23:49","AP01EDTM":"2021-02-19 19:27:23","AP02SDTM":"2021-02-19 19:27:23","AP02EDTM":"2022-02-20 01:27:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":951,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-21","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4614,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.09539,"AVALU":"mg/L","BASE2":10.09539,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"4","BTOXGR":"0","ADTM":"2019-10-20 04:23:49","ADY":97,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-14-id-117","SUBJID":"id-117","SITEID":"PAK-14","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-14","INVNAM":"Dr. PAK-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.26523,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-15 04:23:49","TRTEDTM":"2022-02-20 01:27:23","TRT01SDTM":"2019-07-15 04:23:49","TRT01EDTM":"2021-02-19 19:27:23","TRT02SDTM":"2021-02-19 19:27:23","TRT02EDTM":"2022-02-20 01:27:23","AP01SDTM":"2019-07-15 04:23:49","AP01EDTM":"2021-02-19 19:27:23","AP02SDTM":"2021-02-19 19:27:23","AP02EDTM":"2022-02-20 01:27:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":951,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-21","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7182,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.09455,"AVALU":"mg/L","BASE2":10.09539,"BASE":8.09455,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.00084,"PCHG2":-19.81933,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-28 04:23:49","ADY":136,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-14-id-117","SUBJID":"id-117","SITEID":"PAK-14","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-14","INVNAM":"Dr. PAK-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.26523,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-15 04:23:49","TRTEDTM":"2022-02-20 01:27:23","TRT01SDTM":"2019-07-15 04:23:49","TRT01EDTM":"2021-02-19 19:27:23","TRT02SDTM":"2021-02-19 19:27:23","TRT02EDTM":"2022-02-20 01:27:23","AP01SDTM":"2019-07-15 04:23:49","AP01EDTM":"2021-02-19 19:27:23","AP02SDTM":"2021-02-19 19:27:23","AP02EDTM":"2022-02-20 01:27:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":951,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-21","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1568,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.95195,"AVALU":"mg/L","BASE2":10.09539,"BASE":8.09455,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14343,"PCHG2":-1.42079,"CHG":1.8574,"PCHG":22.94636,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-25 04:23:49","ADY":225,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-14-id-117","SUBJID":"id-117","SITEID":"PAK-14","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-14","INVNAM":"Dr. PAK-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.26523,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-15 04:23:49","TRTEDTM":"2022-02-20 01:27:23","TRT01SDTM":"2019-07-15 04:23:49","TRT01EDTM":"2021-02-19 19:27:23","TRT02SDTM":"2021-02-19 19:27:23","TRT02EDTM":"2022-02-20 01:27:23","AP01SDTM":"2019-07-15 04:23:49","AP01EDTM":"2021-02-19 19:27:23","AP02SDTM":"2021-02-19 19:27:23","AP02EDTM":"2022-02-20 01:27:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":951,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-21","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4082,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":12.54922,"AVALU":"mg/L","BASE2":10.09539,"BASE":8.09455,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.45384,"PCHG2":24.30651,"CHG":4.45467,"PCHG":55.03302,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-06-08 04:23:49","ADY":329,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-14-id-117","SUBJID":"id-117","SITEID":"PAK-14","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-14","INVNAM":"Dr. PAK-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.26523,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-15 04:23:49","TRTEDTM":"2022-02-20 01:27:23","TRT01SDTM":"2019-07-15 04:23:49","TRT01EDTM":"2021-02-19 19:27:23","TRT02SDTM":"2021-02-19 19:27:23","TRT02EDTM":"2022-02-20 01:27:23","AP01SDTM":"2019-07-15 04:23:49","AP01EDTM":"2021-02-19 19:27:23","AP02SDTM":"2021-02-19 19:27:23","AP02EDTM":"2022-02-20 01:27:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":951,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-21","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8147,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.42032,"AVALU":"mg/L","BASE2":10.09539,"BASE":8.09455,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.67507,"PCHG2":-6.68691,"CHG":1.32577,"PCHG":16.37855,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-14 04:23:49","ADY":396,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-14-id-117","SUBJID":"id-117","SITEID":"PAK-14","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-14","INVNAM":"Dr. PAK-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.26523,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-15 04:23:49","TRTEDTM":"2022-02-20 01:27:23","TRT01SDTM":"2019-07-15 04:23:49","TRT01EDTM":"2021-02-19 19:27:23","TRT02SDTM":"2021-02-19 19:27:23","TRT02EDTM":"2022-02-20 01:27:23","AP01SDTM":"2019-07-15 04:23:49","AP01EDTM":"2021-02-19 19:27:23","AP02SDTM":"2021-02-19 19:27:23","AP02EDTM":"2022-02-20 01:27:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":951,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-21","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3281,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.25132,"AVALU":"mg/L","BASE2":10.09539,"BASE":8.09455,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.84406,"PCHG2":-18.26639,"CHG":0.15678,"PCHG":1.93681,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-13 04:23:49","ADY":548,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-14-id-117","SUBJID":"id-117","SITEID":"PAK-14","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-14","INVNAM":"Dr. PAK-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.26523,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-15 04:23:49","TRTEDTM":"2022-02-20 01:27:23","TRT01SDTM":"2019-07-15 04:23:49","TRT01EDTM":"2021-02-19 19:27:23","TRT02SDTM":"2021-02-19 19:27:23","TRT02EDTM":"2022-02-20 01:27:23","AP01SDTM":"2019-07-15 04:23:49","AP01EDTM":"2021-02-19 19:27:23","AP02SDTM":"2021-02-19 19:27:23","AP02EDTM":"2022-02-20 01:27:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":951,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-21","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":600,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.46855,"AVALU":"mg/L","BASE2":10.09539,"BASE":8.09455,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.37317,"PCHG2":3.6964,"CHG":2.374,"PCHG":29.32844,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2022-01-14 04:23:49","ADY":914,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-14-id-117","SUBJID":"id-117","SITEID":"PAK-14","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-14","INVNAM":"Dr. PAK-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.26523,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-15 04:23:49","TRTEDTM":"2022-02-20 01:27:23","TRT01SDTM":"2019-07-15 04:23:49","TRT01EDTM":"2021-02-19 19:27:23","TRT02SDTM":"2021-02-19 19:27:23","TRT02EDTM":"2022-02-20 01:27:23","AP01SDTM":"2019-07-15 04:23:49","AP01EDTM":"2021-02-19 19:27:23","AP02SDTM":"2021-02-19 19:27:23","AP02EDTM":"2022-02-20 01:27:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":951,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-21","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8140,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.08774,"AVALU":"g/L","BASE2":3.08774,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"2","BTOXGR":"0","ADTM":"2019-10-20 04:23:49","ADY":97,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-14-id-117","SUBJID":"id-117","SITEID":"PAK-14","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-14","INVNAM":"Dr. PAK-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.26523,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-15 04:23:49","TRTEDTM":"2022-02-20 01:27:23","TRT01SDTM":"2019-07-15 04:23:49","TRT01EDTM":"2021-02-19 19:27:23","TRT02SDTM":"2021-02-19 19:27:23","TRT02EDTM":"2022-02-20 01:27:23","AP01SDTM":"2019-07-15 04:23:49","AP01EDTM":"2021-02-19 19:27:23","AP02SDTM":"2021-02-19 19:27:23","AP02EDTM":"2022-02-20 01:27:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":951,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-21","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":310,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88952,"AVALU":"g/L","BASE2":3.08774,"BASE":2.88952,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.19823,"PCHG2":-6.41981,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-28 04:23:49","ADY":136,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-14-id-117","SUBJID":"id-117","SITEID":"PAK-14","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-14","INVNAM":"Dr. PAK-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.26523,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-15 04:23:49","TRTEDTM":"2022-02-20 01:27:23","TRT01SDTM":"2019-07-15 04:23:49","TRT01EDTM":"2021-02-19 19:27:23","TRT02SDTM":"2021-02-19 19:27:23","TRT02EDTM":"2022-02-20 01:27:23","AP01SDTM":"2019-07-15 04:23:49","AP01EDTM":"2021-02-19 19:27:23","AP02SDTM":"2021-02-19 19:27:23","AP02EDTM":"2022-02-20 01:27:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":951,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-21","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5459,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89963,"AVALU":"g/L","BASE2":3.08774,"BASE":2.88952,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18811,"PCHG2":-6.09221,"CHG":0.01012,"PCHG":0.35008,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-25 04:23:49","ADY":225,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-14-id-117","SUBJID":"id-117","SITEID":"PAK-14","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-14","INVNAM":"Dr. PAK-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.26523,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-15 04:23:49","TRTEDTM":"2022-02-20 01:27:23","TRT01SDTM":"2019-07-15 04:23:49","TRT01EDTM":"2021-02-19 19:27:23","TRT02SDTM":"2021-02-19 19:27:23","TRT02EDTM":"2022-02-20 01:27:23","AP01SDTM":"2019-07-15 04:23:49","AP01EDTM":"2021-02-19 19:27:23","AP02SDTM":"2021-02-19 19:27:23","AP02EDTM":"2022-02-20 01:27:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":951,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-21","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7189,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91808,"AVALU":"g/L","BASE2":3.08774,"BASE":2.88952,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16967,"PCHG2":-5.49483,"CHG":0.02856,"PCHG":0.98844,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-08 04:23:49","ADY":329,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-14-id-117","SUBJID":"id-117","SITEID":"PAK-14","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-14","INVNAM":"Dr. PAK-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.26523,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-15 04:23:49","TRTEDTM":"2022-02-20 01:27:23","TRT01SDTM":"2019-07-15 04:23:49","TRT01EDTM":"2021-02-19 19:27:23","TRT02SDTM":"2021-02-19 19:27:23","TRT02EDTM":"2022-02-20 01:27:23","AP01SDTM":"2019-07-15 04:23:49","AP01EDTM":"2021-02-19 19:27:23","AP02SDTM":"2021-02-19 19:27:23","AP02EDTM":"2022-02-20 01:27:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":951,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-21","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6869,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9433,"AVALU":"g/L","BASE2":3.08774,"BASE":2.88952,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14444,"PCHG2":-4.67795,"CHG":0.05378,"PCHG":1.86136,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-14 04:23:49","ADY":396,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-14-id-117","SUBJID":"id-117","SITEID":"PAK-14","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-14","INVNAM":"Dr. PAK-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.26523,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-15 04:23:49","TRTEDTM":"2022-02-20 01:27:23","TRT01SDTM":"2019-07-15 04:23:49","TRT01EDTM":"2021-02-19 19:27:23","TRT02SDTM":"2021-02-19 19:27:23","TRT02EDTM":"2022-02-20 01:27:23","AP01SDTM":"2019-07-15 04:23:49","AP01EDTM":"2021-02-19 19:27:23","AP02SDTM":"2021-02-19 19:27:23","AP02EDTM":"2022-02-20 01:27:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":951,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-21","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4859,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91794,"AVALU":"g/L","BASE2":3.08774,"BASE":2.88952,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16981,"PCHG2":-5.49943,"CHG":0.02842,"PCHG":0.98352,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-13 04:23:49","ADY":548,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-14-id-117","SUBJID":"id-117","SITEID":"PAK-14","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-14","INVNAM":"Dr. PAK-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":6.26523,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-11","TRTSDTM":"2019-07-15 04:23:49","TRTEDTM":"2022-02-20 01:27:23","TRT01SDTM":"2019-07-15 04:23:49","TRT01EDTM":"2021-02-19 19:27:23","TRT02SDTM":"2021-02-19 19:27:23","TRT02EDTM":"2022-02-20 01:27:23","AP01SDTM":"2019-07-15 04:23:49","AP01EDTM":"2021-02-19 19:27:23","AP02SDTM":"2021-02-19 19:27:23","AP02EDTM":"2022-02-20 01:27:23","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-20","EOSDY":951,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-21","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4744,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.06083,"AVALU":"g/L","BASE2":3.08774,"BASE":2.88952,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02692,"PCHG2":-0.87172,"CHG":0.17131,"PCHG":5.9287,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2022-01-14 04:23:49","ADY":914,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-15-id-314","SUBJID":"id-314","SITEID":"PAK-15","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-15","INVNAM":"Dr. PAK-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.51131,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-17 23:08:16","TRT01SDTM":"2019-09-17 23:08:16","AP01SDTM":"2019-09-17 23:08:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6210,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.79633,"AVALU":"U/L","BASE2":11.79633,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-19 23:08:16","ADY":93,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-15-id-314","SUBJID":"id-314","SITEID":"PAK-15","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-15","INVNAM":"Dr. PAK-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.51131,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-17 23:08:16","TRT01SDTM":"2019-09-17 23:08:16","AP01SDTM":"2019-09-17 23:08:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3282,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.41248,"AVALU":"U/L","BASE2":11.79633,"BASE":21.41248,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":9.61615,"PCHG2":81.51813,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-18 23:08:16","ADY":214,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-15-id-314","SUBJID":"id-314","SITEID":"PAK-15","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-15","INVNAM":"Dr. PAK-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.51131,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-17 23:08:16","TRT01SDTM":"2019-09-17 23:08:16","AP01SDTM":"2019-09-17 23:08:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3851,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.05484,"AVALU":"U/L","BASE2":11.79633,"BASE":21.41248,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.7415,"PCHG2":-99.53515,"CHG":-21.35765,"PCHG":-99.74391,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-06-15 23:08:16","ADY":272,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-15-id-314","SUBJID":"id-314","SITEID":"PAK-15","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-15","INVNAM":"Dr. PAK-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.51131,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-17 23:08:16","TRT01SDTM":"2019-09-17 23:08:16","AP01SDTM":"2019-09-17 23:08:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7942,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.68165,"AVALU":"U/L","BASE2":11.79633,"BASE":21.41248,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.88532,"PCHG2":126.18596,"CHG":5.26917,"PCHG":24.60791,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-25 23:08:16","ADY":404,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-15-id-314","SUBJID":"id-314","SITEID":"PAK-15","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-15","INVNAM":"Dr. PAK-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.51131,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-17 23:08:16","TRT01SDTM":"2019-09-17 23:08:16","AP01SDTM":"2019-09-17 23:08:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4623,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.19884,"AVALU":"U/L","BASE2":11.79633,"BASE":21.41248,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.59749,"PCHG2":-72.88273,"CHG":-18.21364,"PCHG":-85.06085,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-07-23 23:08:16","ADY":675,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-15-id-314","SUBJID":"id-314","SITEID":"PAK-15","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-15","INVNAM":"Dr. PAK-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.51131,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-17 23:08:16","TRT01SDTM":"2019-09-17 23:08:16","AP01SDTM":"2019-09-17 23:08:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3606,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.68666,"AVALU":"U/L","BASE2":11.79633,"BASE":21.41248,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":17.89032,"PCHG2":151.66004,"CHG":8.27417,"PCHG":38.64181,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-28 23:08:16","ADY":680,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-15-id-314","SUBJID":"id-314","SITEID":"PAK-15","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-15","INVNAM":"Dr. PAK-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.51131,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-17 23:08:16","TRT01SDTM":"2019-09-17 23:08:16","AP01SDTM":"2019-09-17 23:08:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4400,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.35084,"AVALU":"U/L","BASE2":11.79633,"BASE":21.41248,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.55451,"PCHG2":157.29046,"CHG":8.93836,"PCHG":41.74367,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-19 23:08:16","ADY":702,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-15-id-314","SUBJID":"id-314","SITEID":"PAK-15","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-15","INVNAM":"Dr. PAK-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.51131,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-17 23:08:16","TRT01SDTM":"2019-09-17 23:08:16","AP01SDTM":"2019-09-17 23:08:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5642,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.87742,"AVALU":"mg/L","BASE2":7.87742,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2019-12-19 23:08:16","ADY":93,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-15-id-314","SUBJID":"id-314","SITEID":"PAK-15","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-15","INVNAM":"Dr. PAK-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.51131,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-17 23:08:16","TRT01SDTM":"2019-09-17 23:08:16","AP01SDTM":"2019-09-17 23:08:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2243,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.49549,"AVALU":"mg/L","BASE2":7.87742,"BASE":8.49549,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.61807,"PCHG2":7.84604,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-18 23:08:16","ADY":214,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-15-id-314","SUBJID":"id-314","SITEID":"PAK-15","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-15","INVNAM":"Dr. PAK-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.51131,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-17 23:08:16","TRT01SDTM":"2019-09-17 23:08:16","AP01SDTM":"2019-09-17 23:08:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7401,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.15113,"AVALU":"mg/L","BASE2":7.87742,"BASE":8.49549,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.27371,"PCHG2":28.8636,"CHG":1.65564,"PCHG":19.48849,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-06-15 23:08:16","ADY":272,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-15-id-314","SUBJID":"id-314","SITEID":"PAK-15","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-15","INVNAM":"Dr. PAK-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.51131,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-17 23:08:16","TRT01SDTM":"2019-09-17 23:08:16","AP01SDTM":"2019-09-17 23:08:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6875,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.16205,"AVALU":"mg/L","BASE2":7.87742,"BASE":8.49549,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.28462,"PCHG2":3.61315,"CHG":-0.33344,"PCHG":-3.92494,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-25 23:08:16","ADY":404,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-15-id-314","SUBJID":"id-314","SITEID":"PAK-15","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-15","INVNAM":"Dr. PAK-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.51131,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-17 23:08:16","TRT01SDTM":"2019-09-17 23:08:16","AP01SDTM":"2019-09-17 23:08:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8248,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.34691,"AVALU":"mg/L","BASE2":7.87742,"BASE":8.49549,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.46948,"PCHG2":5.95985,"CHG":-0.14858,"PCHG":-1.74896,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-23 23:08:16","ADY":675,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-15-id-314","SUBJID":"id-314","SITEID":"PAK-15","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-15","INVNAM":"Dr. PAK-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.51131,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-17 23:08:16","TRT01SDTM":"2019-09-17 23:08:16","AP01SDTM":"2019-09-17 23:08:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8271,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.25531,"AVALU":"mg/L","BASE2":7.87742,"BASE":8.49549,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.37788,"PCHG2":17.49155,"CHG":0.75982,"PCHG":8.94378,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-28 23:08:16","ADY":680,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-15-id-314","SUBJID":"id-314","SITEID":"PAK-15","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-15","INVNAM":"Dr. PAK-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.51131,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-17 23:08:16","TRT01SDTM":"2019-09-17 23:08:16","AP01SDTM":"2019-09-17 23:08:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3526,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.76713,"AVALU":"mg/L","BASE2":7.87742,"BASE":8.49549,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.88971,"PCHG2":11.29441,"CHG":0.27164,"PCHG":3.19749,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-19 23:08:16","ADY":702,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-15-id-314","SUBJID":"id-314","SITEID":"PAK-15","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-15","INVNAM":"Dr. PAK-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.51131,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-17 23:08:16","TRT01SDTM":"2019-09-17 23:08:16","AP01SDTM":"2019-09-17 23:08:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7263,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92278,"AVALU":"g/L","BASE2":2.92278,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-19 23:08:16","ADY":93,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-15-id-314","SUBJID":"id-314","SITEID":"PAK-15","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-15","INVNAM":"Dr. PAK-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.51131,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-17 23:08:16","TRT01SDTM":"2019-09-17 23:08:16","AP01SDTM":"2019-09-17 23:08:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7510,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80711,"AVALU":"g/L","BASE2":2.92278,"BASE":2.80711,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.11567,"PCHG2":-3.95756,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-18 23:08:16","ADY":214,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-15-id-314","SUBJID":"id-314","SITEID":"PAK-15","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-15","INVNAM":"Dr. PAK-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.51131,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-17 23:08:16","TRT01SDTM":"2019-09-17 23:08:16","AP01SDTM":"2019-09-17 23:08:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2788,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81523,"AVALU":"g/L","BASE2":2.92278,"BASE":2.80711,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10755,"PCHG2":-3.67977,"CHG":0.00812,"PCHG":0.28923,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-15 23:08:16","ADY":272,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-15-id-314","SUBJID":"id-314","SITEID":"PAK-15","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-15","INVNAM":"Dr. PAK-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.51131,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-17 23:08:16","TRT01SDTM":"2019-09-17 23:08:16","AP01SDTM":"2019-09-17 23:08:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":782,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96187,"AVALU":"g/L","BASE2":2.92278,"BASE":2.80711,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03909,"PCHG2":1.33738,"CHG":0.15476,"PCHG":5.51313,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-25 23:08:16","ADY":404,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-15-id-314","SUBJID":"id-314","SITEID":"PAK-15","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-15","INVNAM":"Dr. PAK-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.51131,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-17 23:08:16","TRT01SDTM":"2019-09-17 23:08:16","AP01SDTM":"2019-09-17 23:08:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6605,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0568,"AVALU":"g/L","BASE2":2.92278,"BASE":2.80711,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13402,"PCHG2":4.58532,"CHG":0.24969,"PCHG":8.8949,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-07-23 23:08:16","ADY":675,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-15-id-314","SUBJID":"id-314","SITEID":"PAK-15","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-15","INVNAM":"Dr. PAK-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.51131,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-17 23:08:16","TRT01SDTM":"2019-09-17 23:08:16","AP01SDTM":"2019-09-17 23:08:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1346,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85142,"AVALU":"g/L","BASE2":2.92278,"BASE":2.80711,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07136,"PCHG2":-2.44168,"CHG":0.04431,"PCHG":1.57835,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-28 23:08:16","ADY":680,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-15-id-314","SUBJID":"id-314","SITEID":"PAK-15","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-15","INVNAM":"Dr. PAK-15 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S1","BMRKR1":3.51131,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-13","TRTSDTM":"2019-09-17 23:08:16","TRT01SDTM":"2019-09-17 23:08:16","AP01SDTM":"2019-09-17 23:08:16","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1508,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8244,"AVALU":"g/L","BASE2":2.92278,"BASE":2.80711,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09838,"PCHG2":-3.36594,"CHG":0.01729,"PCHG":0.616,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-19 23:08:16","ADY":702,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-188","SUBJID":"id-188","SITEID":"PAK-2","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":16.48767,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-12 10:44:07","TRTEDTM":"2023-03-13 04:44:07","TRT01SDTM":"2020-03-12 10:44:07","TRT01EDTM":"2022-03-12 22:44:07","TRT02SDTM":"2022-03-12 22:44:07","TRT02EDTM":"2023-03-13 04:44:07","AP01SDTM":"2020-03-12 10:44:07","AP01EDTM":"2022-03-12 22:44:07","AP02SDTM":"2022-03-12 22:44:07","AP02EDTM":"2023-03-13 04:44:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-13","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":683,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.55291,"AVALU":"U/L","BASE2":17.55291,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-22 10:44:07","ADY":194,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-188","SUBJID":"id-188","SITEID":"PAK-2","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":16.48767,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-12 10:44:07","TRTEDTM":"2023-03-13 04:44:07","TRT01SDTM":"2020-03-12 10:44:07","TRT01EDTM":"2022-03-12 22:44:07","TRT02SDTM":"2022-03-12 22:44:07","TRT02EDTM":"2023-03-13 04:44:07","AP01SDTM":"2020-03-12 10:44:07","AP01EDTM":"2022-03-12 22:44:07","AP02SDTM":"2022-03-12 22:44:07","AP02EDTM":"2023-03-13 04:44:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-13","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8294,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.82511,"AVALU":"U/L","BASE2":17.55291,"BASE":30.82511,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":13.2722,"PCHG2":75.61256,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-30 10:44:07","ADY":232,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-188","SUBJID":"id-188","SITEID":"PAK-2","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":16.48767,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-12 10:44:07","TRTEDTM":"2023-03-13 04:44:07","TRT01SDTM":"2020-03-12 10:44:07","TRT01EDTM":"2022-03-12 22:44:07","TRT02SDTM":"2022-03-12 22:44:07","TRT02EDTM":"2023-03-13 04:44:07","AP01SDTM":"2020-03-12 10:44:07","AP01EDTM":"2022-03-12 22:44:07","AP02SDTM":"2022-03-12 22:44:07","AP02EDTM":"2023-03-13 04:44:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-13","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7812,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.54072,"AVALU":"U/L","BASE2":17.55291,"BASE":30.82511,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.98781,"PCHG2":96.7806,"CHG":3.71561,"PCHG":12.05383,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-08 10:44:07","ADY":241,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-188","SUBJID":"id-188","SITEID":"PAK-2","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":16.48767,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-12 10:44:07","TRTEDTM":"2023-03-13 04:44:07","TRT01SDTM":"2020-03-12 10:44:07","TRT01EDTM":"2022-03-12 22:44:07","TRT02SDTM":"2022-03-12 22:44:07","TRT02EDTM":"2023-03-13 04:44:07","AP01SDTM":"2020-03-12 10:44:07","AP01EDTM":"2022-03-12 22:44:07","AP02SDTM":"2022-03-12 22:44:07","AP02EDTM":"2023-03-13 04:44:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-13","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":963,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.75347,"AVALU":"U/L","BASE2":17.55291,"BASE":30.82511,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.20056,"PCHG2":6.83968,"CHG":-12.07164,"PCHG":-39.16171,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-23 10:44:07","ADY":590,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-188","SUBJID":"id-188","SITEID":"PAK-2","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":16.48767,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-12 10:44:07","TRTEDTM":"2023-03-13 04:44:07","TRT01SDTM":"2020-03-12 10:44:07","TRT01EDTM":"2022-03-12 22:44:07","TRT02SDTM":"2022-03-12 22:44:07","TRT02EDTM":"2023-03-13 04:44:07","AP01SDTM":"2020-03-12 10:44:07","AP01EDTM":"2022-03-12 22:44:07","AP02SDTM":"2022-03-12 22:44:07","AP02EDTM":"2023-03-13 04:44:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-13","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2061,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.56787,"AVALU":"U/L","BASE2":17.55291,"BASE":30.82511,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.98504,"PCHG2":-34.09715,"CHG":-19.25725,"PCHG":-62.47259,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-06 10:44:07","ADY":969,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-188","SUBJID":"id-188","SITEID":"PAK-2","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":16.48767,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-12 10:44:07","TRTEDTM":"2023-03-13 04:44:07","TRT01SDTM":"2020-03-12 10:44:07","TRT01EDTM":"2022-03-12 22:44:07","TRT02SDTM":"2022-03-12 22:44:07","TRT02EDTM":"2023-03-13 04:44:07","AP01SDTM":"2020-03-12 10:44:07","AP01EDTM":"2022-03-12 22:44:07","AP02SDTM":"2022-03-12 22:44:07","AP02EDTM":"2023-03-13 04:44:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-13","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":76,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.97586,"AVALU":"U/L","BASE2":17.55291,"BASE":30.82511,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.57704,"PCHG2":-8.98452,"CHG":-14.84925,"PCHG":-48.17257,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-26 10:44:07","ADY":1019,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-188","SUBJID":"id-188","SITEID":"PAK-2","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":16.48767,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-12 10:44:07","TRTEDTM":"2023-03-13 04:44:07","TRT01SDTM":"2020-03-12 10:44:07","TRT01EDTM":"2022-03-12 22:44:07","TRT02SDTM":"2022-03-12 22:44:07","TRT02EDTM":"2023-03-13 04:44:07","AP01SDTM":"2020-03-12 10:44:07","AP01EDTM":"2022-03-12 22:44:07","AP02SDTM":"2022-03-12 22:44:07","AP02EDTM":"2023-03-13 04:44:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-13","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1661,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.88738,"AVALU":"U/L","BASE2":17.55291,"BASE":30.82511,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.66553,"PCHG2":-37.97395,"CHG":-19.93774,"PCHG":-64.68018,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-14 10:44:07","ADY":1038,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-188","SUBJID":"id-188","SITEID":"PAK-2","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":16.48767,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-12 10:44:07","TRTEDTM":"2023-03-13 04:44:07","TRT01SDTM":"2020-03-12 10:44:07","TRT01EDTM":"2022-03-12 22:44:07","TRT02SDTM":"2022-03-12 22:44:07","TRT02EDTM":"2023-03-13 04:44:07","AP01SDTM":"2020-03-12 10:44:07","AP01EDTM":"2022-03-12 22:44:07","AP02SDTM":"2022-03-12 22:44:07","AP02EDTM":"2023-03-13 04:44:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-13","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6296,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.35695,"AVALU":"mg/L","BASE2":8.35695,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"2","ADTM":"2020-09-22 10:44:07","ADY":194,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-188","SUBJID":"id-188","SITEID":"PAK-2","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":16.48767,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-12 10:44:07","TRTEDTM":"2023-03-13 04:44:07","TRT01SDTM":"2020-03-12 10:44:07","TRT01EDTM":"2022-03-12 22:44:07","TRT02SDTM":"2022-03-12 22:44:07","TRT02EDTM":"2023-03-13 04:44:07","AP01SDTM":"2020-03-12 10:44:07","AP01EDTM":"2022-03-12 22:44:07","AP02SDTM":"2022-03-12 22:44:07","AP02EDTM":"2023-03-13 04:44:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-13","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7545,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.27015,"AVALU":"mg/L","BASE2":8.35695,"BASE":10.27015,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.9132,"PCHG2":22.89355,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2020-10-30 10:44:07","ADY":232,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-188","SUBJID":"id-188","SITEID":"PAK-2","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":16.48767,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-12 10:44:07","TRTEDTM":"2023-03-13 04:44:07","TRT01SDTM":"2020-03-12 10:44:07","TRT01EDTM":"2022-03-12 22:44:07","TRT02SDTM":"2022-03-12 22:44:07","TRT02EDTM":"2023-03-13 04:44:07","AP01SDTM":"2020-03-12 10:44:07","AP01EDTM":"2022-03-12 22:44:07","AP02SDTM":"2022-03-12 22:44:07","AP02EDTM":"2023-03-13 04:44:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-13","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":582,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.71984,"AVALU":"mg/L","BASE2":8.35695,"BASE":10.27015,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.3629,"PCHG2":4.34244,"CHG":-1.55031,"PCHG":-15.09526,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2020-11-08 10:44:07","ADY":241,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-188","SUBJID":"id-188","SITEID":"PAK-2","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":16.48767,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-12 10:44:07","TRTEDTM":"2023-03-13 04:44:07","TRT01SDTM":"2020-03-12 10:44:07","TRT01EDTM":"2022-03-12 22:44:07","TRT02SDTM":"2022-03-12 22:44:07","TRT02EDTM":"2023-03-13 04:44:07","AP01SDTM":"2020-03-12 10:44:07","AP01EDTM":"2022-03-12 22:44:07","AP02SDTM":"2022-03-12 22:44:07","AP02EDTM":"2023-03-13 04:44:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-13","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8302,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.25048,"AVALU":"mg/L","BASE2":8.35695,"BASE":10.27015,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.89353,"PCHG2":10.69212,"CHG":-1.01967,"PCHG":-9.92845,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-10-23 10:44:07","ADY":590,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-188","SUBJID":"id-188","SITEID":"PAK-2","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":16.48767,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-12 10:44:07","TRTEDTM":"2023-03-13 04:44:07","TRT01SDTM":"2020-03-12 10:44:07","TRT01EDTM":"2022-03-12 22:44:07","TRT02SDTM":"2022-03-12 22:44:07","TRT02EDTM":"2023-03-13 04:44:07","AP01SDTM":"2020-03-12 10:44:07","AP01EDTM":"2022-03-12 22:44:07","AP02SDTM":"2022-03-12 22:44:07","AP02EDTM":"2023-03-13 04:44:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-13","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":254,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.3207,"AVALU":"mg/L","BASE2":8.35695,"BASE":10.27015,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03625,"PCHG2":-0.43376,"CHG":-1.94945,"PCHG":-18.98172,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-11-06 10:44:07","ADY":969,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-188","SUBJID":"id-188","SITEID":"PAK-2","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":16.48767,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-12 10:44:07","TRTEDTM":"2023-03-13 04:44:07","TRT01SDTM":"2020-03-12 10:44:07","TRT01EDTM":"2022-03-12 22:44:07","TRT02SDTM":"2022-03-12 22:44:07","TRT02EDTM":"2023-03-13 04:44:07","AP01SDTM":"2020-03-12 10:44:07","AP01EDTM":"2022-03-12 22:44:07","AP02SDTM":"2022-03-12 22:44:07","AP02EDTM":"2023-03-13 04:44:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-13","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5712,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.56955,"AVALU":"mg/L","BASE2":8.35695,"BASE":10.27015,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.2126,"PCHG2":14.51013,"CHG":-0.7006,"PCHG":-6.82169,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-12-26 10:44:07","ADY":1019,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-188","SUBJID":"id-188","SITEID":"PAK-2","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":16.48767,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-12 10:44:07","TRTEDTM":"2023-03-13 04:44:07","TRT01SDTM":"2020-03-12 10:44:07","TRT01EDTM":"2022-03-12 22:44:07","TRT02SDTM":"2022-03-12 22:44:07","TRT02EDTM":"2023-03-13 04:44:07","AP01SDTM":"2020-03-12 10:44:07","AP01EDTM":"2022-03-12 22:44:07","AP02SDTM":"2022-03-12 22:44:07","AP02EDTM":"2023-03-13 04:44:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-13","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3474,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.6422,"AVALU":"mg/L","BASE2":8.35695,"BASE":10.27015,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.71475,"PCHG2":-20.5188,"CHG":-3.62795,"PCHG":-35.32517,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-1","BTOXGR":"2","ADTM":"2023-01-14 10:44:07","ADY":1038,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-188","SUBJID":"id-188","SITEID":"PAK-2","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":16.48767,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-12 10:44:07","TRTEDTM":"2023-03-13 04:44:07","TRT01SDTM":"2020-03-12 10:44:07","TRT01EDTM":"2022-03-12 22:44:07","TRT02SDTM":"2022-03-12 22:44:07","TRT02EDTM":"2023-03-13 04:44:07","AP01SDTM":"2020-03-12 10:44:07","AP01EDTM":"2022-03-12 22:44:07","AP02SDTM":"2022-03-12 22:44:07","AP02EDTM":"2023-03-13 04:44:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-13","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3784,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89016,"AVALU":"g/L","BASE2":2.89016,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-22 10:44:07","ADY":194,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-188","SUBJID":"id-188","SITEID":"PAK-2","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":16.48767,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-12 10:44:07","TRTEDTM":"2023-03-13 04:44:07","TRT01SDTM":"2020-03-12 10:44:07","TRT01EDTM":"2022-03-12 22:44:07","TRT02SDTM":"2022-03-12 22:44:07","TRT02EDTM":"2023-03-13 04:44:07","AP01SDTM":"2020-03-12 10:44:07","AP01EDTM":"2022-03-12 22:44:07","AP02SDTM":"2022-03-12 22:44:07","AP02EDTM":"2023-03-13 04:44:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-13","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4604,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94756,"AVALU":"g/L","BASE2":2.89016,"BASE":2.94756,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.0574,"PCHG2":1.98615,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-30 10:44:07","ADY":232,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-188","SUBJID":"id-188","SITEID":"PAK-2","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":16.48767,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-12 10:44:07","TRTEDTM":"2023-03-13 04:44:07","TRT01SDTM":"2020-03-12 10:44:07","TRT01EDTM":"2022-03-12 22:44:07","TRT02SDTM":"2022-03-12 22:44:07","TRT02EDTM":"2023-03-13 04:44:07","AP01SDTM":"2020-03-12 10:44:07","AP01EDTM":"2022-03-12 22:44:07","AP02SDTM":"2022-03-12 22:44:07","AP02EDTM":"2023-03-13 04:44:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-13","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7210,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94852,"AVALU":"g/L","BASE2":2.89016,"BASE":2.94756,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05836,"PCHG2":2.0192,"CHG":0.00096,"PCHG":0.03241,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-08 10:44:07","ADY":241,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-188","SUBJID":"id-188","SITEID":"PAK-2","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":16.48767,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-12 10:44:07","TRTEDTM":"2023-03-13 04:44:07","TRT01SDTM":"2020-03-12 10:44:07","TRT01EDTM":"2022-03-12 22:44:07","TRT02SDTM":"2022-03-12 22:44:07","TRT02EDTM":"2023-03-13 04:44:07","AP01SDTM":"2020-03-12 10:44:07","AP01EDTM":"2022-03-12 22:44:07","AP02SDTM":"2022-03-12 22:44:07","AP02EDTM":"2023-03-13 04:44:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-13","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4814,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81875,"AVALU":"g/L","BASE2":2.89016,"BASE":2.94756,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07141,"PCHG2":-2.47079,"CHG":-0.12881,"PCHG":-4.37015,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-23 10:44:07","ADY":590,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-188","SUBJID":"id-188","SITEID":"PAK-2","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":16.48767,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-12 10:44:07","TRTEDTM":"2023-03-13 04:44:07","TRT01SDTM":"2020-03-12 10:44:07","TRT01EDTM":"2022-03-12 22:44:07","TRT02SDTM":"2022-03-12 22:44:07","TRT02EDTM":"2023-03-13 04:44:07","AP01SDTM":"2020-03-12 10:44:07","AP01EDTM":"2022-03-12 22:44:07","AP02SDTM":"2022-03-12 22:44:07","AP02EDTM":"2023-03-13 04:44:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-13","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4444,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85616,"AVALU":"g/L","BASE2":2.89016,"BASE":2.94756,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.034,"PCHG2":-1.17655,"CHG":-0.09141,"PCHG":-3.10111,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-06 10:44:07","ADY":969,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-188","SUBJID":"id-188","SITEID":"PAK-2","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":16.48767,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-12 10:44:07","TRTEDTM":"2023-03-13 04:44:07","TRT01SDTM":"2020-03-12 10:44:07","TRT01EDTM":"2022-03-12 22:44:07","TRT02SDTM":"2022-03-12 22:44:07","TRT02EDTM":"2023-03-13 04:44:07","AP01SDTM":"2020-03-12 10:44:07","AP01EDTM":"2022-03-12 22:44:07","AP02SDTM":"2022-03-12 22:44:07","AP02EDTM":"2023-03-13 04:44:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-13","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2948,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88908,"AVALU":"g/L","BASE2":2.89016,"BASE":2.94756,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00108,"PCHG2":-0.03721,"CHG":-0.05848,"PCHG":-1.98395,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-12-26 10:44:07","ADY":1019,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-188","SUBJID":"id-188","SITEID":"PAK-2","AGE":23,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":16.48767,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-11","TRTSDTM":"2020-03-12 10:44:07","TRTEDTM":"2023-03-13 04:44:07","TRT01SDTM":"2020-03-12 10:44:07","TRT01EDTM":"2022-03-12 22:44:07","TRT02SDTM":"2022-03-12 22:44:07","TRT02EDTM":"2023-03-13 04:44:07","AP01SDTM":"2020-03-12 10:44:07","AP01EDTM":"2022-03-12 22:44:07","AP02SDTM":"2022-03-12 22:44:07","AP02EDTM":"2023-03-13 04:44:07","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-13","EOSDY":1096,"LSTALVDT":"2023-04-09","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5682,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00293,"AVALU":"g/L","BASE2":2.89016,"BASE":2.94756,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11277,"PCHG2":3.90191,"CHG":0.05537,"PCHG":1.87845,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2023-01-14 10:44:07","ADY":1038,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-191","SUBJID":"id-191","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.14369,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-07 17:15:55","TRTEDTM":"2022-04-07 11:15:55","TRT01SDTM":"2019-04-07 17:15:55","TRT01EDTM":"2021-04-07 05:15:55","TRT02SDTM":"2021-04-07 05:15:55","TRT02EDTM":"2022-04-07 11:15:55","AP01SDTM":"2019-04-07 17:15:55","AP01EDTM":"2021-04-07 05:15:55","AP02SDTM":"2021-04-07 05:15:55","AP02EDTM":"2022-04-07 11:15:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-07","EOSDY":1096,"LSTALVDT":"2022-04-27","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7149,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.74565,"AVALU":"U/L","BASE2":18.74565,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-09 17:15:55","ADY":246,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-191","SUBJID":"id-191","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.14369,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-07 17:15:55","TRTEDTM":"2022-04-07 11:15:55","TRT01SDTM":"2019-04-07 17:15:55","TRT01EDTM":"2021-04-07 05:15:55","TRT02SDTM":"2021-04-07 05:15:55","TRT02EDTM":"2022-04-07 11:15:55","AP01SDTM":"2019-04-07 17:15:55","AP01EDTM":"2021-04-07 05:15:55","AP02SDTM":"2021-04-07 05:15:55","AP02EDTM":"2022-04-07 11:15:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-07","EOSDY":1096,"LSTALVDT":"2022-04-27","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":570,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.61727,"AVALU":"U/L","BASE2":18.74565,"BASE":19.61727,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.87162,"PCHG2":4.64971,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-16 17:15:55","ADY":284,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-191","SUBJID":"id-191","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.14369,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-07 17:15:55","TRTEDTM":"2022-04-07 11:15:55","TRT01SDTM":"2019-04-07 17:15:55","TRT01EDTM":"2021-04-07 05:15:55","TRT02SDTM":"2021-04-07 05:15:55","TRT02EDTM":"2022-04-07 11:15:55","AP01SDTM":"2019-04-07 17:15:55","AP01EDTM":"2021-04-07 05:15:55","AP02SDTM":"2021-04-07 05:15:55","AP02EDTM":"2022-04-07 11:15:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-07","EOSDY":1096,"LSTALVDT":"2022-04-27","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8389,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.02612,"AVALU":"U/L","BASE2":18.74565,"BASE":19.61727,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.71953,"PCHG2":-94.52611,"CHG":-18.59115,"PCHG":-94.76932,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-01-26 17:15:55","ADY":294,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-191","SUBJID":"id-191","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.14369,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-07 17:15:55","TRTEDTM":"2022-04-07 11:15:55","TRT01SDTM":"2019-04-07 17:15:55","TRT01EDTM":"2021-04-07 05:15:55","TRT02SDTM":"2021-04-07 05:15:55","TRT02EDTM":"2022-04-07 11:15:55","AP01SDTM":"2019-04-07 17:15:55","AP01EDTM":"2021-04-07 05:15:55","AP02SDTM":"2021-04-07 05:15:55","AP02EDTM":"2022-04-07 11:15:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-07","EOSDY":1096,"LSTALVDT":"2022-04-27","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":19,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.86217,"AVALU":"U/L","BASE2":18.74565,"BASE":19.61727,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.88348,"PCHG2":-15.38212,"CHG":-3.7551,"PCHG":-19.14179,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-10 17:15:55","ADY":734,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-191","SUBJID":"id-191","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.14369,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-07 17:15:55","TRTEDTM":"2022-04-07 11:15:55","TRT01SDTM":"2019-04-07 17:15:55","TRT01EDTM":"2021-04-07 05:15:55","TRT02SDTM":"2021-04-07 05:15:55","TRT02EDTM":"2022-04-07 11:15:55","AP01SDTM":"2019-04-07 17:15:55","AP01EDTM":"2021-04-07 05:15:55","AP02SDTM":"2021-04-07 05:15:55","AP02EDTM":"2022-04-07 11:15:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-07","EOSDY":1096,"LSTALVDT":"2022-04-27","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2018,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.52437,"AVALU":"U/L","BASE2":18.74565,"BASE":19.61727,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.22128,"PCHG2":-43.85699,"CHG":-9.0929,"PCHG":-46.35149,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-28 17:15:55","ADY":752,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-191","SUBJID":"id-191","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.14369,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-07 17:15:55","TRTEDTM":"2022-04-07 11:15:55","TRT01SDTM":"2019-04-07 17:15:55","TRT01EDTM":"2021-04-07 05:15:55","TRT02SDTM":"2021-04-07 05:15:55","TRT02EDTM":"2022-04-07 11:15:55","AP01SDTM":"2019-04-07 17:15:55","AP01EDTM":"2021-04-07 05:15:55","AP02SDTM":"2021-04-07 05:15:55","AP02EDTM":"2022-04-07 11:15:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-07","EOSDY":1096,"LSTALVDT":"2022-04-27","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3553,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.42209,"AVALU":"U/L","BASE2":18.74565,"BASE":19.61727,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.32356,"PCHG2":-92.41375,"CHG":-18.19518,"PCHG":-92.75081,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-06-02 17:15:55","ADY":787,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-191","SUBJID":"id-191","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.14369,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-07 17:15:55","TRTEDTM":"2022-04-07 11:15:55","TRT01SDTM":"2019-04-07 17:15:55","TRT01EDTM":"2021-04-07 05:15:55","TRT02SDTM":"2021-04-07 05:15:55","TRT02EDTM":"2022-04-07 11:15:55","AP01SDTM":"2019-04-07 17:15:55","AP01EDTM":"2021-04-07 05:15:55","AP02SDTM":"2021-04-07 05:15:55","AP02EDTM":"2022-04-07 11:15:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-07","EOSDY":1096,"LSTALVDT":"2022-04-27","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1365,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.29567,"AVALU":"U/L","BASE2":18.74565,"BASE":19.61727,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.55002,"PCHG2":29.607,"CHG":4.67841,"PCHG":23.84841,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-23 17:15:55","ADY":900,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-191","SUBJID":"id-191","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.14369,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-07 17:15:55","TRTEDTM":"2022-04-07 11:15:55","TRT01SDTM":"2019-04-07 17:15:55","TRT01EDTM":"2021-04-07 05:15:55","TRT02SDTM":"2021-04-07 05:15:55","TRT02EDTM":"2022-04-07 11:15:55","AP01SDTM":"2019-04-07 17:15:55","AP01EDTM":"2021-04-07 05:15:55","AP02SDTM":"2021-04-07 05:15:55","AP02EDTM":"2022-04-07 11:15:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-07","EOSDY":1096,"LSTALVDT":"2022-04-27","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5520,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.85517,"AVALU":"mg/L","BASE2":8.85517,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-09 17:15:55","ADY":246,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-191","SUBJID":"id-191","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.14369,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-07 17:15:55","TRTEDTM":"2022-04-07 11:15:55","TRT01SDTM":"2019-04-07 17:15:55","TRT01EDTM":"2021-04-07 05:15:55","TRT02SDTM":"2021-04-07 05:15:55","TRT02EDTM":"2022-04-07 11:15:55","AP01SDTM":"2019-04-07 17:15:55","AP01EDTM":"2021-04-07 05:15:55","AP02SDTM":"2021-04-07 05:15:55","AP02EDTM":"2022-04-07 11:15:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-07","EOSDY":1096,"LSTALVDT":"2022-04-27","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3499,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.06306,"AVALU":"mg/L","BASE2":8.85517,"BASE":8.06306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.79211,"PCHG2":-8.94518,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-16 17:15:55","ADY":284,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-191","SUBJID":"id-191","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.14369,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-07 17:15:55","TRTEDTM":"2022-04-07 11:15:55","TRT01SDTM":"2019-04-07 17:15:55","TRT01EDTM":"2021-04-07 05:15:55","TRT02SDTM":"2021-04-07 05:15:55","TRT02EDTM":"2022-04-07 11:15:55","AP01SDTM":"2019-04-07 17:15:55","AP01EDTM":"2021-04-07 05:15:55","AP02SDTM":"2021-04-07 05:15:55","AP02EDTM":"2022-04-07 11:15:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-07","EOSDY":1096,"LSTALVDT":"2022-04-27","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1381,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.80901,"AVALU":"mg/L","BASE2":8.85517,"BASE":8.06306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.95384,"PCHG2":10.77158,"CHG":1.74595,"PCHG":21.65372,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-26 17:15:55","ADY":294,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-191","SUBJID":"id-191","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.14369,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-07 17:15:55","TRTEDTM":"2022-04-07 11:15:55","TRT01SDTM":"2019-04-07 17:15:55","TRT01EDTM":"2021-04-07 05:15:55","TRT02SDTM":"2021-04-07 05:15:55","TRT02EDTM":"2022-04-07 11:15:55","AP01SDTM":"2019-04-07 17:15:55","AP01EDTM":"2021-04-07 05:15:55","AP02SDTM":"2021-04-07 05:15:55","AP02EDTM":"2022-04-07 11:15:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-07","EOSDY":1096,"LSTALVDT":"2022-04-27","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4582,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.10913,"AVALU":"mg/L","BASE2":8.85517,"BASE":8.06306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.25396,"PCHG2":2.86797,"CHG":1.04607,"PCHG":12.97367,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-10 17:15:55","ADY":734,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-191","SUBJID":"id-191","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.14369,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-07 17:15:55","TRTEDTM":"2022-04-07 11:15:55","TRT01SDTM":"2019-04-07 17:15:55","TRT01EDTM":"2021-04-07 05:15:55","TRT02SDTM":"2021-04-07 05:15:55","TRT02EDTM":"2022-04-07 11:15:55","AP01SDTM":"2019-04-07 17:15:55","AP01EDTM":"2021-04-07 05:15:55","AP02SDTM":"2021-04-07 05:15:55","AP02EDTM":"2022-04-07 11:15:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-07","EOSDY":1096,"LSTALVDT":"2022-04-27","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8148,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.33141,"AVALU":"mg/L","BASE2":8.85517,"BASE":8.06306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.47625,"PCHG2":5.37817,"CHG":1.26836,"PCHG":15.73047,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-28 17:15:55","ADY":752,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-191","SUBJID":"id-191","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.14369,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-07 17:15:55","TRTEDTM":"2022-04-07 11:15:55","TRT01SDTM":"2019-04-07 17:15:55","TRT01EDTM":"2021-04-07 05:15:55","TRT02SDTM":"2021-04-07 05:15:55","TRT02EDTM":"2022-04-07 11:15:55","AP01SDTM":"2019-04-07 17:15:55","AP01EDTM":"2021-04-07 05:15:55","AP02SDTM":"2021-04-07 05:15:55","AP02EDTM":"2022-04-07 11:15:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-07","EOSDY":1096,"LSTALVDT":"2022-04-27","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8136,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.96233,"AVALU":"mg/L","BASE2":8.85517,"BASE":8.06306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.89283,"PCHG2":-10.08263,"CHG":-0.10072,"PCHG":-1.24919,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-06-02 17:15:55","ADY":787,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-191","SUBJID":"id-191","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.14369,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-07 17:15:55","TRTEDTM":"2022-04-07 11:15:55","TRT01SDTM":"2019-04-07 17:15:55","TRT01EDTM":"2021-04-07 05:15:55","TRT02SDTM":"2021-04-07 05:15:55","TRT02EDTM":"2022-04-07 11:15:55","AP01SDTM":"2019-04-07 17:15:55","AP01EDTM":"2021-04-07 05:15:55","AP02SDTM":"2021-04-07 05:15:55","AP02EDTM":"2022-04-07 11:15:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-07","EOSDY":1096,"LSTALVDT":"2022-04-27","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":983,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.73703,"AVALU":"mg/L","BASE2":8.85517,"BASE":8.06306,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11814,"PCHG2":-1.33411,"CHG":0.67397,"PCHG":8.35878,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-23 17:15:55","ADY":900,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-191","SUBJID":"id-191","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.14369,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-07 17:15:55","TRTEDTM":"2022-04-07 11:15:55","TRT01SDTM":"2019-04-07 17:15:55","TRT01EDTM":"2021-04-07 05:15:55","TRT02SDTM":"2021-04-07 05:15:55","TRT02EDTM":"2022-04-07 11:15:55","AP01SDTM":"2019-04-07 17:15:55","AP01EDTM":"2021-04-07 05:15:55","AP02SDTM":"2021-04-07 05:15:55","AP02EDTM":"2022-04-07 11:15:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-07","EOSDY":1096,"LSTALVDT":"2022-04-27","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2478,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78289,"AVALU":"g/L","BASE2":2.78289,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2019-12-09 17:15:55","ADY":246,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-191","SUBJID":"id-191","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.14369,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-07 17:15:55","TRTEDTM":"2022-04-07 11:15:55","TRT01SDTM":"2019-04-07 17:15:55","TRT01EDTM":"2021-04-07 05:15:55","TRT02SDTM":"2021-04-07 05:15:55","TRT02EDTM":"2022-04-07 11:15:55","AP01SDTM":"2019-04-07 17:15:55","AP01EDTM":"2021-04-07 05:15:55","AP02SDTM":"2021-04-07 05:15:55","AP02EDTM":"2022-04-07 11:15:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-07","EOSDY":1096,"LSTALVDT":"2022-04-27","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5744,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05325,"AVALU":"g/L","BASE2":2.78289,"BASE":3.05325,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.27036,"PCHG2":9.71495,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-01-16 17:15:55","ADY":284,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-191","SUBJID":"id-191","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.14369,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-07 17:15:55","TRTEDTM":"2022-04-07 11:15:55","TRT01SDTM":"2019-04-07 17:15:55","TRT01EDTM":"2021-04-07 05:15:55","TRT02SDTM":"2021-04-07 05:15:55","TRT02EDTM":"2022-04-07 11:15:55","AP01SDTM":"2019-04-07 17:15:55","AP01EDTM":"2021-04-07 05:15:55","AP02SDTM":"2021-04-07 05:15:55","AP02EDTM":"2022-04-07 11:15:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-07","EOSDY":1096,"LSTALVDT":"2022-04-27","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5768,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95982,"AVALU":"g/L","BASE2":2.78289,"BASE":3.05325,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17692,"PCHG2":6.35756,"CHG":-0.09343,"PCHG":-3.06011,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-01-26 17:15:55","ADY":294,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-191","SUBJID":"id-191","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.14369,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-07 17:15:55","TRTEDTM":"2022-04-07 11:15:55","TRT01SDTM":"2019-04-07 17:15:55","TRT01EDTM":"2021-04-07 05:15:55","TRT02SDTM":"2021-04-07 05:15:55","TRT02EDTM":"2022-04-07 11:15:55","AP01SDTM":"2019-04-07 17:15:55","AP01EDTM":"2021-04-07 05:15:55","AP02SDTM":"2021-04-07 05:15:55","AP02EDTM":"2022-04-07 11:15:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-07","EOSDY":1096,"LSTALVDT":"2022-04-27","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":987,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93994,"AVALU":"g/L","BASE2":2.78289,"BASE":3.05325,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15704,"PCHG2":5.64319,"CHG":-0.11331,"PCHG":-3.71122,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-04-10 17:15:55","ADY":734,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-191","SUBJID":"id-191","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.14369,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-07 17:15:55","TRTEDTM":"2022-04-07 11:15:55","TRT01SDTM":"2019-04-07 17:15:55","TRT01EDTM":"2021-04-07 05:15:55","TRT02SDTM":"2021-04-07 05:15:55","TRT02EDTM":"2022-04-07 11:15:55","AP01SDTM":"2019-04-07 17:15:55","AP01EDTM":"2021-04-07 05:15:55","AP02SDTM":"2021-04-07 05:15:55","AP02EDTM":"2022-04-07 11:15:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-07","EOSDY":1096,"LSTALVDT":"2022-04-27","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4380,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87847,"AVALU":"g/L","BASE2":2.78289,"BASE":3.05325,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09558,"PCHG2":3.43445,"CHG":-0.17478,"PCHG":-5.72438,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-04-28 17:15:55","ADY":752,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-191","SUBJID":"id-191","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.14369,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-07 17:15:55","TRTEDTM":"2022-04-07 11:15:55","TRT01SDTM":"2019-04-07 17:15:55","TRT01EDTM":"2021-04-07 05:15:55","TRT02SDTM":"2021-04-07 05:15:55","TRT02EDTM":"2022-04-07 11:15:55","AP01SDTM":"2019-04-07 17:15:55","AP01EDTM":"2021-04-07 05:15:55","AP02SDTM":"2021-04-07 05:15:55","AP02EDTM":"2022-04-07 11:15:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-07","EOSDY":1096,"LSTALVDT":"2022-04-27","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8228,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74393,"AVALU":"g/L","BASE2":2.78289,"BASE":3.05325,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03897,"PCHG2":-1.40018,"CHG":-0.30932,"PCHG":-10.13092,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-06-02 17:15:55","ADY":787,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-191","SUBJID":"id-191","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.14369,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-04-03","TRTSDTM":"2019-04-07 17:15:55","TRTEDTM":"2022-04-07 11:15:55","TRT01SDTM":"2019-04-07 17:15:55","TRT01EDTM":"2021-04-07 05:15:55","TRT02SDTM":"2021-04-07 05:15:55","TRT02EDTM":"2022-04-07 11:15:55","AP01SDTM":"2019-04-07 17:15:55","AP01EDTM":"2021-04-07 05:15:55","AP02SDTM":"2021-04-07 05:15:55","AP02EDTM":"2022-04-07 11:15:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-07","EOSDY":1096,"LSTALVDT":"2022-04-27","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1370,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77872,"AVALU":"g/L","BASE2":2.78289,"BASE":3.05325,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00417,"PCHG2":-0.15002,"CHG":-0.27453,"PCHG":-8.99146,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-09-23 17:15:55","ADY":900,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-213","SUBJID":"id-213","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.81794,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-16 13:35:03","TRT01SDTM":"2020-01-16 13:35:03","AP01SDTM":"2020-01-16 13:35:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":885,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.07908,"AVALU":"U/L","BASE2":30.07908,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-29 13:35:03","ADY":44,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-213","SUBJID":"id-213","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.81794,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-16 13:35:03","TRT01SDTM":"2020-01-16 13:35:03","AP01SDTM":"2020-01-16 13:35:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5302,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.42018,"AVALU":"U/L","BASE2":30.07908,"BASE":16.42018,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-13.6589,"PCHG2":-45.40996,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-29 13:35:03","ADY":73,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-213","SUBJID":"id-213","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.81794,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-16 13:35:03","TRT01SDTM":"2020-01-16 13:35:03","AP01SDTM":"2020-01-16 13:35:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6616,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.67877,"AVALU":"U/L","BASE2":30.07908,"BASE":16.42018,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.40032,"PCHG2":-57.84856,"CHG":-3.74142,"PCHG":-22.78548,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-15 13:35:03","ADY":334,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-213","SUBJID":"id-213","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.81794,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-16 13:35:03","TRT01SDTM":"2020-01-16 13:35:03","AP01SDTM":"2020-01-16 13:35:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5188,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.16423,"AVALU":"U/L","BASE2":30.07908,"BASE":16.42018,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.91486,"PCHG2":-29.63806,"CHG":4.74404,"PCHG":28.89155,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-20 13:35:03","ADY":401,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-213","SUBJID":"id-213","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.81794,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-16 13:35:03","TRT01SDTM":"2020-01-16 13:35:03","AP01SDTM":"2020-01-16 13:35:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6923,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.76022,"AVALU":"U/L","BASE2":30.07908,"BASE":16.42018,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.31887,"PCHG2":-40.95493,"CHG":1.34003,"PCHG":8.1609,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-04 13:35:03","ADY":474,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-213","SUBJID":"id-213","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.81794,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-16 13:35:03","TRT01SDTM":"2020-01-16 13:35:03","AP01SDTM":"2020-01-16 13:35:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3938,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.4695,"AVALU":"U/L","BASE2":30.07908,"BASE":16.42018,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.60958,"PCHG2":-45.24601,"CHG":0.04932,"PCHG":0.30034,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-01 13:35:03","ADY":716,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-213","SUBJID":"id-213","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.81794,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-16 13:35:03","TRT01SDTM":"2020-01-16 13:35:03","AP01SDTM":"2020-01-16 13:35:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2027,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.65089,"AVALU":"U/L","BASE2":30.07908,"BASE":16.42018,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.42819,"PCHG2":-28.02011,"CHG":5.23071,"PCHG":31.85537,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-06 13:35:03","ADY":721,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-213","SUBJID":"id-213","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.81794,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-16 13:35:03","TRT01SDTM":"2020-01-16 13:35:03","AP01SDTM":"2020-01-16 13:35:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4484,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.42084,"AVALU":"mg/L","BASE2":8.42084,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-02-29 13:35:03","ADY":44,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-213","SUBJID":"id-213","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.81794,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-16 13:35:03","TRT01SDTM":"2020-01-16 13:35:03","AP01SDTM":"2020-01-16 13:35:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3944,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.10617,"AVALU":"mg/L","BASE2":8.42084,"BASE":10.10617,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.68533,"PCHG2":20.01377,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-03-29 13:35:03","ADY":73,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-213","SUBJID":"id-213","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.81794,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-16 13:35:03","TRT01SDTM":"2020-01-16 13:35:03","AP01SDTM":"2020-01-16 13:35:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4834,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.02507,"AVALU":"mg/L","BASE2":8.42084,"BASE":10.10617,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.39578,"PCHG2":-4.69995,"CHG":-2.0811,"PCHG":-20.5924,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-12-15 13:35:03","ADY":334,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-213","SUBJID":"id-213","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.81794,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-16 13:35:03","TRT01SDTM":"2020-01-16 13:35:03","AP01SDTM":"2020-01-16 13:35:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3278,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.10419,"AVALU":"mg/L","BASE2":8.42084,"BASE":10.10617,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.31665,"PCHG2":-3.76033,"CHG":-2.00198,"PCHG":-19.80947,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-02-20 13:35:03","ADY":401,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-213","SUBJID":"id-213","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.81794,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-16 13:35:03","TRT01SDTM":"2020-01-16 13:35:03","AP01SDTM":"2020-01-16 13:35:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3504,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.40536,"AVALU":"mg/L","BASE2":8.42084,"BASE":10.10617,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.01548,"PCHG2":-12.05915,"CHG":-2.70081,"PCHG":-26.72436,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-1","BTOXGR":"1","ADTM":"2021-05-04 13:35:03","ADY":474,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-213","SUBJID":"id-213","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.81794,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-16 13:35:03","TRT01SDTM":"2020-01-16 13:35:03","AP01SDTM":"2020-01-16 13:35:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4890,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.70868,"AVALU":"mg/L","BASE2":8.42084,"BASE":10.10617,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.71217,"PCHG2":-8.45718,"CHG":-2.39749,"PCHG":-23.72307,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-2","BTOXGR":"1","ADTM":"2022-01-01 13:35:03","ADY":716,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-213","SUBJID":"id-213","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.81794,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-16 13:35:03","TRT01SDTM":"2020-01-16 13:35:03","AP01SDTM":"2020-01-16 13:35:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5991,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.94397,"AVALU":"mg/L","BASE2":8.42084,"BASE":10.10617,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.52313,"PCHG2":6.21229,"CHG":-1.1622,"PCHG":-11.49991,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2022-01-06 13:35:03","ADY":721,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-213","SUBJID":"id-213","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.81794,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-16 13:35:03","TRT01SDTM":"2020-01-16 13:35:03","AP01SDTM":"2020-01-16 13:35:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2958,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81645,"AVALU":"g/L","BASE2":2.81645,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-29 13:35:03","ADY":44,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-213","SUBJID":"id-213","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.81794,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-16 13:35:03","TRT01SDTM":"2020-01-16 13:35:03","AP01SDTM":"2020-01-16 13:35:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7441,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8573,"AVALU":"g/L","BASE2":2.81645,"BASE":2.8573,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.04085,"PCHG2":1.45058,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-29 13:35:03","ADY":73,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-213","SUBJID":"id-213","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.81794,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-16 13:35:03","TRT01SDTM":"2020-01-16 13:35:03","AP01SDTM":"2020-01-16 13:35:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6790,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8656,"AVALU":"g/L","BASE2":2.81645,"BASE":2.8573,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04915,"PCHG2":1.74527,"CHG":0.0083,"PCHG":0.29047,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-15 13:35:03","ADY":334,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-213","SUBJID":"id-213","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.81794,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-16 13:35:03","TRT01SDTM":"2020-01-16 13:35:03","AP01SDTM":"2020-01-16 13:35:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":511,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95327,"AVALU":"g/L","BASE2":2.81645,"BASE":2.8573,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13682,"PCHG2":4.85804,"CHG":0.09597,"PCHG":3.35873,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-20 13:35:03","ADY":401,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-213","SUBJID":"id-213","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.81794,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-16 13:35:03","TRT01SDTM":"2020-01-16 13:35:03","AP01SDTM":"2020-01-16 13:35:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5677,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.64882,"AVALU":"g/L","BASE2":2.81645,"BASE":2.8573,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16763,"PCHG2":-5.95167,"CHG":-0.20848,"PCHG":-7.29642,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-04 13:35:03","ADY":474,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-213","SUBJID":"id-213","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.81794,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-16 13:35:03","TRT01SDTM":"2020-01-16 13:35:03","AP01SDTM":"2020-01-16 13:35:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6387,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84736,"AVALU":"g/L","BASE2":2.81645,"BASE":2.8573,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03091,"PCHG2":1.09755,"CHG":-0.00994,"PCHG":-0.34799,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-01 13:35:03","ADY":716,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-2-id-213","SUBJID":"id-213","SITEID":"PAK-2","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-2","INVNAM":"Dr. PAK-2 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.81794,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-13","TRTSDTM":"2020-01-16 13:35:03","TRT01SDTM":"2020-01-16 13:35:03","AP01SDTM":"2020-01-16 13:35:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6561,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91889,"AVALU":"g/L","BASE2":2.81645,"BASE":2.8573,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10244,"PCHG2":3.63735,"CHG":0.06159,"PCHG":2.15549,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-06 13:35:03","ADY":721,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-15","SUBJID":"id-15","SITEID":"PAK-4","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.81159,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-27 05:43:17","TRTEDTM":"2022-02-14 10:25:12","TRT01SDTM":"2019-12-27 05:43:17","TRT01EDTM":"2021-02-14 04:25:12","TRT02SDTM":"2021-02-14 04:25:12","TRT02EDTM":"2022-02-14 10:25:12","AP01SDTM":"2019-12-27 05:43:17","AP01EDTM":"2021-02-14 04:25:12","AP02SDTM":"2021-02-14 04:25:12","AP02EDTM":"2022-02-14 10:25:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":781,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":811,"ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":330,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.86423,"AVALU":"U/L","BASE2":26.86423,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-11 05:43:17","ADY":289,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-15","SUBJID":"id-15","SITEID":"PAK-4","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.81159,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-27 05:43:17","TRTEDTM":"2022-02-14 10:25:12","TRT01SDTM":"2019-12-27 05:43:17","TRT01EDTM":"2021-02-14 04:25:12","TRT02SDTM":"2021-02-14 04:25:12","TRT02EDTM":"2022-02-14 10:25:12","AP01SDTM":"2019-12-27 05:43:17","AP01EDTM":"2021-02-14 04:25:12","AP02SDTM":"2021-02-14 04:25:12","AP02EDTM":"2022-02-14 10:25:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":781,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":811,"ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2932,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.37152,"AVALU":"U/L","BASE2":26.86423,"BASE":9.37152,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-17.49271,"PCHG2":-65.11524,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-29 05:43:17","ADY":307,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-15","SUBJID":"id-15","SITEID":"PAK-4","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.81159,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-27 05:43:17","TRTEDTM":"2022-02-14 10:25:12","TRT01SDTM":"2019-12-27 05:43:17","TRT01EDTM":"2021-02-14 04:25:12","TRT02SDTM":"2021-02-14 04:25:12","TRT02EDTM":"2022-02-14 10:25:12","AP01SDTM":"2019-12-27 05:43:17","AP01EDTM":"2021-02-14 04:25:12","AP02SDTM":"2021-02-14 04:25:12","AP02EDTM":"2022-02-14 10:25:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":781,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":811,"ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7565,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.40219,"AVALU":"U/L","BASE2":26.86423,"BASE":9.37152,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-19.46204,"PCHG2":-72.44592,"CHG":-1.96933,"PCHG":-21.014,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-27 05:43:17","ADY":456,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-15","SUBJID":"id-15","SITEID":"PAK-4","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.81159,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-27 05:43:17","TRTEDTM":"2022-02-14 10:25:12","TRT01SDTM":"2019-12-27 05:43:17","TRT01EDTM":"2021-02-14 04:25:12","TRT02SDTM":"2021-02-14 04:25:12","TRT02EDTM":"2022-02-14 10:25:12","AP01SDTM":"2019-12-27 05:43:17","AP01EDTM":"2021-02-14 04:25:12","AP02SDTM":"2021-02-14 04:25:12","AP02EDTM":"2022-02-14 10:25:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":781,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":811,"ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8101,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.1266,"AVALU":"U/L","BASE2":26.86423,"BASE":9.37152,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-18.73763,"PCHG2":-69.74937,"CHG":-1.24492,"PCHG":-13.28411,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-02 05:43:17","ADY":523,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-15","SUBJID":"id-15","SITEID":"PAK-4","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.81159,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-27 05:43:17","TRTEDTM":"2022-02-14 10:25:12","TRT01SDTM":"2019-12-27 05:43:17","TRT01EDTM":"2021-02-14 04:25:12","TRT02SDTM":"2021-02-14 04:25:12","TRT02EDTM":"2022-02-14 10:25:12","AP01SDTM":"2019-12-27 05:43:17","AP01EDTM":"2021-02-14 04:25:12","AP02SDTM":"2021-02-14 04:25:12","AP02EDTM":"2022-02-14 10:25:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":781,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":811,"ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5939,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.07128,"AVALU":"U/L","BASE2":26.86423,"BASE":9.37152,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.79295,"PCHG2":-43.89834,"CHG":5.69976,"PCHG":60.81997,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-25 05:43:17","ADY":546,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-15","SUBJID":"id-15","SITEID":"PAK-4","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.81159,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-27 05:43:17","TRTEDTM":"2022-02-14 10:25:12","TRT01SDTM":"2019-12-27 05:43:17","TRT01EDTM":"2021-02-14 04:25:12","TRT02SDTM":"2021-02-14 04:25:12","TRT02EDTM":"2022-02-14 10:25:12","AP01SDTM":"2019-12-27 05:43:17","AP01EDTM":"2021-02-14 04:25:12","AP02SDTM":"2021-02-14 04:25:12","AP02EDTM":"2022-02-14 10:25:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":781,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":811,"ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2364,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.35712,"AVALU":"U/L","BASE2":26.86423,"BASE":9.37152,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-19.50711,"PCHG2":-72.61369,"CHG":-2.0144,"PCHG":-21.49492,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-13 05:43:17","ADY":595,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-15","SUBJID":"id-15","SITEID":"PAK-4","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.81159,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-27 05:43:17","TRTEDTM":"2022-02-14 10:25:12","TRT01SDTM":"2019-12-27 05:43:17","TRT01EDTM":"2021-02-14 04:25:12","TRT02SDTM":"2021-02-14 04:25:12","TRT02EDTM":"2022-02-14 10:25:12","AP01SDTM":"2019-12-27 05:43:17","AP01EDTM":"2021-02-14 04:25:12","AP02SDTM":"2021-02-14 04:25:12","AP02EDTM":"2022-02-14 10:25:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":781,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":811,"ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7376,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.10233,"AVALU":"U/L","BASE2":26.86423,"BASE":9.37152,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.7619,"PCHG2":-6.55852,"CHG":15.73081,"PCHG":167.8576,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-29 05:43:17","ADY":672,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-15","SUBJID":"id-15","SITEID":"PAK-4","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.81159,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-27 05:43:17","TRTEDTM":"2022-02-14 10:25:12","TRT01SDTM":"2019-12-27 05:43:17","TRT01EDTM":"2021-02-14 04:25:12","TRT02SDTM":"2021-02-14 04:25:12","TRT02EDTM":"2022-02-14 10:25:12","AP01SDTM":"2019-12-27 05:43:17","AP01EDTM":"2021-02-14 04:25:12","AP02SDTM":"2021-02-14 04:25:12","AP02EDTM":"2022-02-14 10:25:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":781,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":811,"ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":831,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.30003,"AVALU":"mg/L","BASE2":8.30003,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-11 05:43:17","ADY":289,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-15","SUBJID":"id-15","SITEID":"PAK-4","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.81159,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-27 05:43:17","TRTEDTM":"2022-02-14 10:25:12","TRT01SDTM":"2019-12-27 05:43:17","TRT01EDTM":"2021-02-14 04:25:12","TRT02SDTM":"2021-02-14 04:25:12","TRT02EDTM":"2022-02-14 10:25:12","AP01SDTM":"2019-12-27 05:43:17","AP01EDTM":"2021-02-14 04:25:12","AP02SDTM":"2021-02-14 04:25:12","AP02EDTM":"2022-02-14 10:25:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":781,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":811,"ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6244,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.75004,"AVALU":"mg/L","BASE2":8.30003,"BASE":9.75004,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.45,"PCHG2":17.46983,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-29 05:43:17","ADY":307,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-15","SUBJID":"id-15","SITEID":"PAK-4","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.81159,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-27 05:43:17","TRTEDTM":"2022-02-14 10:25:12","TRT01SDTM":"2019-12-27 05:43:17","TRT01EDTM":"2021-02-14 04:25:12","TRT02SDTM":"2021-02-14 04:25:12","TRT02EDTM":"2022-02-14 10:25:12","AP01SDTM":"2019-12-27 05:43:17","AP01EDTM":"2021-02-14 04:25:12","AP02SDTM":"2021-02-14 04:25:12","AP02EDTM":"2022-02-14 10:25:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":781,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":811,"ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6487,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.82407,"AVALU":"mg/L","BASE2":8.30003,"BASE":9.75004,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.52404,"PCHG2":18.36181,"CHG":0.07403,"PCHG":0.75933,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-27 05:43:17","ADY":456,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-15","SUBJID":"id-15","SITEID":"PAK-4","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.81159,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-27 05:43:17","TRTEDTM":"2022-02-14 10:25:12","TRT01SDTM":"2019-12-27 05:43:17","TRT01EDTM":"2021-02-14 04:25:12","TRT02SDTM":"2021-02-14 04:25:12","TRT02EDTM":"2022-02-14 10:25:12","AP01SDTM":"2019-12-27 05:43:17","AP01EDTM":"2021-02-14 04:25:12","AP02SDTM":"2021-02-14 04:25:12","AP02EDTM":"2022-02-14 10:25:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":781,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":811,"ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1022,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.9283,"AVALU":"mg/L","BASE2":8.30003,"BASE":9.75004,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.62827,"PCHG2":19.61759,"CHG":0.17826,"PCHG":1.82835,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-02 05:43:17","ADY":523,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-15","SUBJID":"id-15","SITEID":"PAK-4","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.81159,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-27 05:43:17","TRTEDTM":"2022-02-14 10:25:12","TRT01SDTM":"2019-12-27 05:43:17","TRT01EDTM":"2021-02-14 04:25:12","TRT02SDTM":"2021-02-14 04:25:12","TRT02EDTM":"2022-02-14 10:25:12","AP01SDTM":"2019-12-27 05:43:17","AP01EDTM":"2021-02-14 04:25:12","AP02SDTM":"2021-02-14 04:25:12","AP02EDTM":"2022-02-14 10:25:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":781,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":811,"ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4061,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.62166,"AVALU":"mg/L","BASE2":8.30003,"BASE":9.75004,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.32163,"PCHG2":3.87502,"CHG":-1.12837,"PCHG":-11.57303,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-25 05:43:17","ADY":546,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-15","SUBJID":"id-15","SITEID":"PAK-4","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.81159,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-27 05:43:17","TRTEDTM":"2022-02-14 10:25:12","TRT01SDTM":"2019-12-27 05:43:17","TRT01EDTM":"2021-02-14 04:25:12","TRT02SDTM":"2021-02-14 04:25:12","TRT02EDTM":"2022-02-14 10:25:12","AP01SDTM":"2019-12-27 05:43:17","AP01EDTM":"2021-02-14 04:25:12","AP02SDTM":"2021-02-14 04:25:12","AP02EDTM":"2022-02-14 10:25:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":781,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":811,"ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5394,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.5191,"AVALU":"mg/L","BASE2":8.30003,"BASE":9.75004,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.78094,"PCHG2":-9.40885,"CHG":-2.23094,"PCHG":-22.88135,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-08-13 05:43:17","ADY":595,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-15","SUBJID":"id-15","SITEID":"PAK-4","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.81159,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-27 05:43:17","TRTEDTM":"2022-02-14 10:25:12","TRT01SDTM":"2019-12-27 05:43:17","TRT01EDTM":"2021-02-14 04:25:12","TRT02SDTM":"2021-02-14 04:25:12","TRT02EDTM":"2022-02-14 10:25:12","AP01SDTM":"2019-12-27 05:43:17","AP01EDTM":"2021-02-14 04:25:12","AP02SDTM":"2021-02-14 04:25:12","AP02EDTM":"2022-02-14 10:25:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":781,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":811,"ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6958,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.64857,"AVALU":"mg/L","BASE2":8.30003,"BASE":9.75004,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.34854,"PCHG2":4.19924,"CHG":-1.10146,"PCHG":-11.29702,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-29 05:43:17","ADY":672,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-15","SUBJID":"id-15","SITEID":"PAK-4","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.81159,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-27 05:43:17","TRTEDTM":"2022-02-14 10:25:12","TRT01SDTM":"2019-12-27 05:43:17","TRT01EDTM":"2021-02-14 04:25:12","TRT02SDTM":"2021-02-14 04:25:12","TRT02EDTM":"2022-02-14 10:25:12","AP01SDTM":"2019-12-27 05:43:17","AP01EDTM":"2021-02-14 04:25:12","AP02SDTM":"2021-02-14 04:25:12","AP02EDTM":"2022-02-14 10:25:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":781,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":811,"ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2200,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85061,"AVALU":"g/L","BASE2":2.85061,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-11 05:43:17","ADY":289,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-15","SUBJID":"id-15","SITEID":"PAK-4","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.81159,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-27 05:43:17","TRTEDTM":"2022-02-14 10:25:12","TRT01SDTM":"2019-12-27 05:43:17","TRT01EDTM":"2021-02-14 04:25:12","TRT02SDTM":"2021-02-14 04:25:12","TRT02EDTM":"2022-02-14 10:25:12","AP01SDTM":"2019-12-27 05:43:17","AP01EDTM":"2021-02-14 04:25:12","AP02SDTM":"2021-02-14 04:25:12","AP02EDTM":"2022-02-14 10:25:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":781,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":811,"ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2325,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85786,"AVALU":"g/L","BASE2":2.85061,"BASE":2.85786,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.00725,"PCHG2":0.25425,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-29 05:43:17","ADY":307,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-15","SUBJID":"id-15","SITEID":"PAK-4","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.81159,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-27 05:43:17","TRTEDTM":"2022-02-14 10:25:12","TRT01SDTM":"2019-12-27 05:43:17","TRT01EDTM":"2021-02-14 04:25:12","TRT02SDTM":"2021-02-14 04:25:12","TRT02EDTM":"2022-02-14 10:25:12","AP01SDTM":"2019-12-27 05:43:17","AP01EDTM":"2021-02-14 04:25:12","AP02SDTM":"2021-02-14 04:25:12","AP02EDTM":"2022-02-14 10:25:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":781,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":811,"ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3431,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92262,"AVALU":"g/L","BASE2":2.85061,"BASE":2.85786,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07201,"PCHG2":2.52616,"CHG":0.06476,"PCHG":2.26616,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-27 05:43:17","ADY":456,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-15","SUBJID":"id-15","SITEID":"PAK-4","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.81159,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-27 05:43:17","TRTEDTM":"2022-02-14 10:25:12","TRT01SDTM":"2019-12-27 05:43:17","TRT01EDTM":"2021-02-14 04:25:12","TRT02SDTM":"2021-02-14 04:25:12","TRT02EDTM":"2022-02-14 10:25:12","AP01SDTM":"2019-12-27 05:43:17","AP01EDTM":"2021-02-14 04:25:12","AP02SDTM":"2021-02-14 04:25:12","AP02EDTM":"2022-02-14 10:25:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":781,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":811,"ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5493,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93731,"AVALU":"g/L","BASE2":2.85061,"BASE":2.85786,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08669,"PCHG2":3.04119,"CHG":0.07944,"PCHG":2.77987,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-02 05:43:17","ADY":523,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-15","SUBJID":"id-15","SITEID":"PAK-4","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.81159,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-27 05:43:17","TRTEDTM":"2022-02-14 10:25:12","TRT01SDTM":"2019-12-27 05:43:17","TRT01EDTM":"2021-02-14 04:25:12","TRT02SDTM":"2021-02-14 04:25:12","TRT02EDTM":"2022-02-14 10:25:12","AP01SDTM":"2019-12-27 05:43:17","AP01EDTM":"2021-02-14 04:25:12","AP02SDTM":"2021-02-14 04:25:12","AP02EDTM":"2022-02-14 10:25:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":781,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":811,"ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1315,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7707,"AVALU":"g/L","BASE2":2.85061,"BASE":2.85786,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07991,"PCHG2":-2.80324,"CHG":-0.08716,"PCHG":-3.04973,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-25 05:43:17","ADY":546,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-15","SUBJID":"id-15","SITEID":"PAK-4","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.81159,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-27 05:43:17","TRTEDTM":"2022-02-14 10:25:12","TRT01SDTM":"2019-12-27 05:43:17","TRT01EDTM":"2021-02-14 04:25:12","TRT02SDTM":"2021-02-14 04:25:12","TRT02EDTM":"2022-02-14 10:25:12","AP01SDTM":"2019-12-27 05:43:17","AP01EDTM":"2021-02-14 04:25:12","AP02SDTM":"2021-02-14 04:25:12","AP02EDTM":"2022-02-14 10:25:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":781,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":811,"ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6696,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90345,"AVALU":"g/L","BASE2":2.85061,"BASE":2.85786,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05284,"PCHG2":1.85354,"CHG":0.04559,"PCHG":1.59524,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-13 05:43:17","ADY":595,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-15","SUBJID":"id-15","SITEID":"PAK-4","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"Y","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":8.81159,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-25","TRTSDTM":"2019-12-27 05:43:17","TRTEDTM":"2022-02-14 10:25:12","TRT01SDTM":"2019-12-27 05:43:17","TRT01EDTM":"2021-02-14 04:25:12","TRT02SDTM":"2021-02-14 04:25:12","TRT02EDTM":"2022-02-14 10:25:12","AP01SDTM":"2019-12-27 05:43:17","AP01EDTM":"2021-02-14 04:25:12","AP02SDTM":"2021-02-14 04:25:12","AP02EDTM":"2022-02-14 10:25:12","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":781,"DCSREAS":"DEATH","DTHDT":"2022-03-18","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":32,"LDDTHGR1":">30","LSTALVDT":"2022-03-18","DTHADY":811,"ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5539,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93866,"AVALU":"g/L","BASE2":2.85061,"BASE":2.85786,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08804,"PCHG2":3.08854,"CHG":0.08079,"PCHG":2.82711,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-29 05:43:17","ADY":672,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-164","SUBJID":"id-164","SITEID":"PAK-4","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.8305,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-27","TRTSDTM":"2019-11-30 22:27:22","TRT01SDTM":"2019-11-30 22:27:22","AP01SDTM":"2019-11-30 22:27:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7947,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.13699,"AVALU":"U/L","BASE2":5.13699,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-2","BTOXGR":"0","ADTM":"2019-12-10 22:27:22","ADY":10,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-164","SUBJID":"id-164","SITEID":"PAK-4","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.8305,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-27","TRTSDTM":"2019-11-30 22:27:22","TRT01SDTM":"2019-11-30 22:27:22","AP01SDTM":"2019-11-30 22:27:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4370,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.1048,"AVALU":"U/L","BASE2":5.13699,"BASE":17.1048,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":11.96781,"PCHG2":232.97292,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-28 22:27:22","ADY":28,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-164","SUBJID":"id-164","SITEID":"PAK-4","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.8305,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-27","TRTSDTM":"2019-11-30 22:27:22","TRT01SDTM":"2019-11-30 22:27:22","AP01SDTM":"2019-11-30 22:27:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5239,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.06776,"AVALU":"U/L","BASE2":5.13699,"BASE":17.1048,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.93076,"PCHG2":57.05209,"CHG":-9.03704,"PCHG":-52.83338,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-27 22:27:22","ADY":271,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-164","SUBJID":"id-164","SITEID":"PAK-4","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.8305,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-27","TRTSDTM":"2019-11-30 22:27:22","TRT01SDTM":"2019-11-30 22:27:22","AP01SDTM":"2019-11-30 22:27:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1244,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.35623,"AVALU":"U/L","BASE2":5.13699,"BASE":17.1048,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.21924,"PCHG2":140.53431,"CHG":-4.74857,"PCHG":-27.7616,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-11 22:27:22","ADY":377,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-164","SUBJID":"id-164","SITEID":"PAK-4","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.8305,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-27","TRTSDTM":"2019-11-30 22:27:22","TRT01SDTM":"2019-11-30 22:27:22","AP01SDTM":"2019-11-30 22:27:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3967,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.7762,"AVALU":"U/L","BASE2":5.13699,"BASE":17.1048,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.6392,"PCHG2":70.84299,"CHG":-8.32861,"PCHG":-48.69163,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-09 22:27:22","ADY":406,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-164","SUBJID":"id-164","SITEID":"PAK-4","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.8305,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-27","TRTSDTM":"2019-11-30 22:27:22","TRT01SDTM":"2019-11-30 22:27:22","AP01SDTM":"2019-11-30 22:27:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2390,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.22107,"AVALU":"U/L","BASE2":5.13699,"BASE":17.1048,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.08408,"PCHG2":352.03618,"CHG":6.11627,"PCHG":35.75764,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-02 22:27:22","ADY":430,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-164","SUBJID":"id-164","SITEID":"PAK-4","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.8305,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-27","TRTSDTM":"2019-11-30 22:27:22","TRT01SDTM":"2019-11-30 22:27:22","AP01SDTM":"2019-11-30 22:27:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5359,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.63385,"AVALU":"U/L","BASE2":5.13699,"BASE":17.1048,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":25.49685,"PCHG2":496.33795,"CHG":13.52905,"PCHG":79.09503,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-10 22:27:22","ADY":588,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-164","SUBJID":"id-164","SITEID":"PAK-4","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.8305,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-27","TRTSDTM":"2019-11-30 22:27:22","TRT01SDTM":"2019-11-30 22:27:22","AP01SDTM":"2019-11-30 22:27:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3752,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.40496,"AVALU":"mg/L","BASE2":8.40496,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-10 22:27:22","ADY":10,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-164","SUBJID":"id-164","SITEID":"PAK-4","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.8305,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-27","TRTSDTM":"2019-11-30 22:27:22","TRT01SDTM":"2019-11-30 22:27:22","AP01SDTM":"2019-11-30 22:27:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1005,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.49998,"AVALU":"mg/L","BASE2":8.40496,"BASE":8.49998,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.09502,"PCHG2":1.13052,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-28 22:27:22","ADY":28,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-164","SUBJID":"id-164","SITEID":"PAK-4","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.8305,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-27","TRTSDTM":"2019-11-30 22:27:22","TRT01SDTM":"2019-11-30 22:27:22","AP01SDTM":"2019-11-30 22:27:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2449,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.99387,"AVALU":"mg/L","BASE2":8.40496,"BASE":8.49998,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.58891,"PCHG2":7.00671,"CHG":0.49389,"PCHG":5.81051,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-27 22:27:22","ADY":271,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-164","SUBJID":"id-164","SITEID":"PAK-4","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.8305,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-27","TRTSDTM":"2019-11-30 22:27:22","TRT01SDTM":"2019-11-30 22:27:22","AP01SDTM":"2019-11-30 22:27:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1954,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.61797,"AVALU":"mg/L","BASE2":8.40496,"BASE":8.49998,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.21301,"PCHG2":2.53438,"CHG":0.11799,"PCHG":1.38817,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-11 22:27:22","ADY":377,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-164","SUBJID":"id-164","SITEID":"PAK-4","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.8305,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-27","TRTSDTM":"2019-11-30 22:27:22","TRT01SDTM":"2019-11-30 22:27:22","AP01SDTM":"2019-11-30 22:27:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8165,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.97047,"AVALU":"mg/L","BASE2":8.40496,"BASE":8.49998,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.43449,"PCHG2":-5.16939,"CHG":-0.5295,"PCHG":-6.22948,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-01-09 22:27:22","ADY":406,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-164","SUBJID":"id-164","SITEID":"PAK-4","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.8305,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-27","TRTSDTM":"2019-11-30 22:27:22","TRT01SDTM":"2019-11-30 22:27:22","AP01SDTM":"2019-11-30 22:27:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2946,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.57554,"AVALU":"mg/L","BASE2":8.40496,"BASE":8.49998,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17058,"PCHG2":2.02951,"CHG":0.07556,"PCHG":0.88894,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-02 22:27:22","ADY":430,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-164","SUBJID":"id-164","SITEID":"PAK-4","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.8305,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-27","TRTSDTM":"2019-11-30 22:27:22","TRT01SDTM":"2019-11-30 22:27:22","AP01SDTM":"2019-11-30 22:27:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7832,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.44987,"AVALU":"mg/L","BASE2":8.40496,"BASE":8.49998,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.95509,"PCHG2":-11.3634,"CHG":-1.05011,"PCHG":-12.35424,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-07-10 22:27:22","ADY":588,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-164","SUBJID":"id-164","SITEID":"PAK-4","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.8305,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-27","TRTSDTM":"2019-11-30 22:27:22","TRT01SDTM":"2019-11-30 22:27:22","AP01SDTM":"2019-11-30 22:27:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3340,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01038,"AVALU":"g/L","BASE2":3.01038,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"4","BTOXGR":"2","ADTM":"2019-12-10 22:27:22","ADY":10,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-164","SUBJID":"id-164","SITEID":"PAK-4","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.8305,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-27","TRTSDTM":"2019-11-30 22:27:22","TRT01SDTM":"2019-11-30 22:27:22","AP01SDTM":"2019-11-30 22:27:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1218,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02367,"AVALU":"g/L","BASE2":3.01038,"BASE":3.02367,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.01329,"PCHG2":0.44163,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2019-12-28 22:27:22","ADY":28,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-164","SUBJID":"id-164","SITEID":"PAK-4","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.8305,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-27","TRTSDTM":"2019-11-30 22:27:22","TRT01SDTM":"2019-11-30 22:27:22","AP01SDTM":"2019-11-30 22:27:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3643,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.74774,"AVALU":"g/L","BASE2":3.01038,"BASE":3.02367,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.26264,"PCHG2":-8.72437,"CHG":-0.27593,"PCHG":-9.12569,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2020-08-27 22:27:22","ADY":271,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-164","SUBJID":"id-164","SITEID":"PAK-4","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.8305,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-27","TRTSDTM":"2019-11-30 22:27:22","TRT01SDTM":"2019-11-30 22:27:22","AP01SDTM":"2019-11-30 22:27:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6748,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84629,"AVALU":"g/L","BASE2":3.01038,"BASE":3.02367,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.16408,"PCHG2":-5.45063,"CHG":-0.17738,"PCHG":-5.86635,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2020-12-11 22:27:22","ADY":377,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-164","SUBJID":"id-164","SITEID":"PAK-4","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.8305,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-27","TRTSDTM":"2019-11-30 22:27:22","TRT01SDTM":"2019-11-30 22:27:22","AP01SDTM":"2019-11-30 22:27:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3747,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85839,"AVALU":"g/L","BASE2":3.01038,"BASE":3.02367,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15199,"PCHG2":-5.04874,"CHG":-0.16528,"PCHG":-5.46623,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-01-09 22:27:22","ADY":406,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-164","SUBJID":"id-164","SITEID":"PAK-4","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.8305,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-27","TRTSDTM":"2019-11-30 22:27:22","TRT01SDTM":"2019-11-30 22:27:22","AP01SDTM":"2019-11-30 22:27:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3638,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.72224,"AVALU":"g/L","BASE2":3.01038,"BASE":3.02367,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.28814,"PCHG2":-9.57145,"CHG":-0.30143,"PCHG":-9.96905,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-02-02 22:27:22","ADY":430,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-4-id-164","SUBJID":"id-164","SITEID":"PAK-4","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-4","INVNAM":"Dr. PAK-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Asia","STRATA1":"B","STRATA2":"S1","BMRKR1":1.8305,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-11-27","TRTSDTM":"2019-11-30 22:27:22","TRT01SDTM":"2019-11-30 22:27:22","AP01SDTM":"2019-11-30 22:27:22","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6671,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89834,"AVALU":"g/L","BASE2":3.01038,"BASE":3.02367,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11204,"PCHG2":-3.72169,"CHG":-0.12533,"PCHG":-4.14501,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-07-10 22:27:22","ADY":588,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-5-id-20","SUBJID":"id-20","SITEID":"PAK-5","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-5","INVNAM":"Dr. PAK-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.84789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-20","TRTSDTM":"2020-09-21 06:37:27","TRTEDTM":"2023-09-22 00:37:27","TRT01SDTM":"2020-09-21 06:37:27","TRT01EDTM":"2022-09-21 18:37:27","TRT02SDTM":"2022-09-21 18:37:27","TRT02EDTM":"2023-09-22 00:37:27","AP01SDTM":"2020-09-21 06:37:27","AP01EDTM":"2022-09-21 18:37:27","AP02SDTM":"2022-09-21 18:37:27","AP02EDTM":"2023-09-22 00:37:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-22","EOSDY":1096,"LSTALVDT":"2023-10-11","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1819,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.0586,"AVALU":"U/L","BASE2":5.0586,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-10-20 06:37:27","ADY":29,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-5-id-20","SUBJID":"id-20","SITEID":"PAK-5","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-5","INVNAM":"Dr. PAK-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.84789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-20","TRTSDTM":"2020-09-21 06:37:27","TRTEDTM":"2023-09-22 00:37:27","TRT01SDTM":"2020-09-21 06:37:27","TRT01EDTM":"2022-09-21 18:37:27","TRT02SDTM":"2022-09-21 18:37:27","TRT02EDTM":"2023-09-22 00:37:27","AP01SDTM":"2020-09-21 06:37:27","AP01EDTM":"2022-09-21 18:37:27","AP02SDTM":"2022-09-21 18:37:27","AP02EDTM":"2023-09-22 00:37:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-22","EOSDY":1096,"LSTALVDT":"2023-10-11","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5018,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.45985,"AVALU":"U/L","BASE2":5.0586,"BASE":16.45985,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":11.40125,"PCHG2":225.38355,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-09 06:37:27","ADY":49,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-5-id-20","SUBJID":"id-20","SITEID":"PAK-5","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-5","INVNAM":"Dr. PAK-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.84789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-20","TRTSDTM":"2020-09-21 06:37:27","TRTEDTM":"2023-09-22 00:37:27","TRT01SDTM":"2020-09-21 06:37:27","TRT01EDTM":"2022-09-21 18:37:27","TRT02SDTM":"2022-09-21 18:37:27","TRT02EDTM":"2023-09-22 00:37:27","AP01SDTM":"2020-09-21 06:37:27","AP01EDTM":"2022-09-21 18:37:27","AP02SDTM":"2022-09-21 18:37:27","AP02EDTM":"2023-09-22 00:37:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-22","EOSDY":1096,"LSTALVDT":"2023-10-11","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2165,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.08605,"AVALU":"U/L","BASE2":5.0586,"BASE":16.45985,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02745,"PCHG2":0.54263,"CHG":-11.3738,"PCHG":-69.10027,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-12-20 06:37:27","ADY":90,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-5-id-20","SUBJID":"id-20","SITEID":"PAK-5","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-5","INVNAM":"Dr. PAK-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.84789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-20","TRTSDTM":"2020-09-21 06:37:27","TRTEDTM":"2023-09-22 00:37:27","TRT01SDTM":"2020-09-21 06:37:27","TRT01EDTM":"2022-09-21 18:37:27","TRT02SDTM":"2022-09-21 18:37:27","TRT02EDTM":"2023-09-22 00:37:27","AP01SDTM":"2020-09-21 06:37:27","AP01EDTM":"2022-09-21 18:37:27","AP02SDTM":"2022-09-21 18:37:27","AP02EDTM":"2023-09-22 00:37:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-22","EOSDY":1096,"LSTALVDT":"2023-10-11","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":798,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.9667,"AVALU":"U/L","BASE2":5.0586,"BASE":16.45985,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.9081,"PCHG2":235.403,"CHG":0.50684,"PCHG":3.07927,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-11 06:37:27","ADY":567,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-5-id-20","SUBJID":"id-20","SITEID":"PAK-5","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-5","INVNAM":"Dr. PAK-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.84789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-20","TRTSDTM":"2020-09-21 06:37:27","TRTEDTM":"2023-09-22 00:37:27","TRT01SDTM":"2020-09-21 06:37:27","TRT01EDTM":"2022-09-21 18:37:27","TRT02SDTM":"2022-09-21 18:37:27","TRT02EDTM":"2023-09-22 00:37:27","AP01SDTM":"2020-09-21 06:37:27","AP01EDTM":"2022-09-21 18:37:27","AP02SDTM":"2022-09-21 18:37:27","AP02EDTM":"2023-09-22 00:37:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-22","EOSDY":1096,"LSTALVDT":"2023-10-11","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":452,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.27813,"AVALU":"U/L","BASE2":5.0586,"BASE":16.45985,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.21953,"PCHG2":300.86457,"CHG":3.81828,"PCHG":23.19755,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-02 06:37:27","ADY":619,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-5-id-20","SUBJID":"id-20","SITEID":"PAK-5","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-5","INVNAM":"Dr. PAK-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.84789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-20","TRTSDTM":"2020-09-21 06:37:27","TRTEDTM":"2023-09-22 00:37:27","TRT01SDTM":"2020-09-21 06:37:27","TRT01EDTM":"2022-09-21 18:37:27","TRT02SDTM":"2022-09-21 18:37:27","TRT02EDTM":"2023-09-22 00:37:27","AP01SDTM":"2020-09-21 06:37:27","AP01EDTM":"2022-09-21 18:37:27","AP02SDTM":"2022-09-21 18:37:27","AP02EDTM":"2023-09-22 00:37:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-22","EOSDY":1096,"LSTALVDT":"2023-10-11","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2187,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.64739,"AVALU":"U/L","BASE2":5.0586,"BASE":16.45985,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":23.58879,"PCHG2":466.31069,"CHG":12.18754,"PCHG":74.04405,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-26 06:37:27","ADY":704,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-5-id-20","SUBJID":"id-20","SITEID":"PAK-5","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-5","INVNAM":"Dr. PAK-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.84789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-20","TRTSDTM":"2020-09-21 06:37:27","TRTEDTM":"2023-09-22 00:37:27","TRT01SDTM":"2020-09-21 06:37:27","TRT01EDTM":"2022-09-21 18:37:27","TRT02SDTM":"2022-09-21 18:37:27","TRT02EDTM":"2023-09-22 00:37:27","AP01SDTM":"2020-09-21 06:37:27","AP01EDTM":"2022-09-21 18:37:27","AP02SDTM":"2022-09-21 18:37:27","AP02EDTM":"2023-09-22 00:37:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-22","EOSDY":1096,"LSTALVDT":"2023-10-11","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":643,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.95002,"AVALU":"U/L","BASE2":5.0586,"BASE":16.45985,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":28.89142,"PCHG2":571.13479,"CHG":17.49017,"PCHG":106.25959,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-06 06:37:27","ADY":1080,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-5-id-20","SUBJID":"id-20","SITEID":"PAK-5","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-5","INVNAM":"Dr. PAK-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.84789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-20","TRTSDTM":"2020-09-21 06:37:27","TRTEDTM":"2023-09-22 00:37:27","TRT01SDTM":"2020-09-21 06:37:27","TRT01EDTM":"2022-09-21 18:37:27","TRT02SDTM":"2022-09-21 18:37:27","TRT02EDTM":"2023-09-22 00:37:27","AP01SDTM":"2020-09-21 06:37:27","AP01EDTM":"2022-09-21 18:37:27","AP02SDTM":"2022-09-21 18:37:27","AP02EDTM":"2023-09-22 00:37:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-22","EOSDY":1096,"LSTALVDT":"2023-10-11","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4193,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.90509,"AVALU":"mg/L","BASE2":8.90509,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-20 06:37:27","ADY":29,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-5-id-20","SUBJID":"id-20","SITEID":"PAK-5","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-5","INVNAM":"Dr. PAK-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.84789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-20","TRTSDTM":"2020-09-21 06:37:27","TRTEDTM":"2023-09-22 00:37:27","TRT01SDTM":"2020-09-21 06:37:27","TRT01EDTM":"2022-09-21 18:37:27","TRT02SDTM":"2022-09-21 18:37:27","TRT02EDTM":"2023-09-22 00:37:27","AP01SDTM":"2020-09-21 06:37:27","AP01EDTM":"2022-09-21 18:37:27","AP02SDTM":"2022-09-21 18:37:27","AP02EDTM":"2023-09-22 00:37:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-22","EOSDY":1096,"LSTALVDT":"2023-10-11","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8364,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.28699,"AVALU":"mg/L","BASE2":8.90509,"BASE":9.28699,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.3819,"PCHG2":4.28857,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-09 06:37:27","ADY":49,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-5-id-20","SUBJID":"id-20","SITEID":"PAK-5","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-5","INVNAM":"Dr. PAK-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.84789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-20","TRTSDTM":"2020-09-21 06:37:27","TRTEDTM":"2023-09-22 00:37:27","TRT01SDTM":"2020-09-21 06:37:27","TRT01EDTM":"2022-09-21 18:37:27","TRT02SDTM":"2022-09-21 18:37:27","TRT02EDTM":"2023-09-22 00:37:27","AP01SDTM":"2020-09-21 06:37:27","AP01EDTM":"2022-09-21 18:37:27","AP02SDTM":"2022-09-21 18:37:27","AP02EDTM":"2023-09-22 00:37:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-22","EOSDY":1096,"LSTALVDT":"2023-10-11","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7302,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.66617,"AVALU":"mg/L","BASE2":8.90509,"BASE":9.28699,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.23892,"PCHG2":-13.91251,"CHG":-1.62082,"PCHG":-17.45261,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-12-20 06:37:27","ADY":90,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-5-id-20","SUBJID":"id-20","SITEID":"PAK-5","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-5","INVNAM":"Dr. PAK-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.84789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-20","TRTSDTM":"2020-09-21 06:37:27","TRTEDTM":"2023-09-22 00:37:27","TRT01SDTM":"2020-09-21 06:37:27","TRT01EDTM":"2022-09-21 18:37:27","TRT02SDTM":"2022-09-21 18:37:27","TRT02EDTM":"2023-09-22 00:37:27","AP01SDTM":"2020-09-21 06:37:27","AP01EDTM":"2022-09-21 18:37:27","AP02SDTM":"2022-09-21 18:37:27","AP02EDTM":"2023-09-22 00:37:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-22","EOSDY":1096,"LSTALVDT":"2023-10-11","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3837,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.17843,"AVALU":"mg/L","BASE2":8.90509,"BASE":9.28699,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.72666,"PCHG2":-8.16004,"CHG":-1.10856,"PCHG":-11.9367,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-11 06:37:27","ADY":567,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-5-id-20","SUBJID":"id-20","SITEID":"PAK-5","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-5","INVNAM":"Dr. PAK-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.84789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-20","TRTSDTM":"2020-09-21 06:37:27","TRTEDTM":"2023-09-22 00:37:27","TRT01SDTM":"2020-09-21 06:37:27","TRT01EDTM":"2022-09-21 18:37:27","TRT02SDTM":"2022-09-21 18:37:27","TRT02EDTM":"2023-09-22 00:37:27","AP01SDTM":"2020-09-21 06:37:27","AP01EDTM":"2022-09-21 18:37:27","AP02SDTM":"2022-09-21 18:37:27","AP02EDTM":"2023-09-22 00:37:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-22","EOSDY":1096,"LSTALVDT":"2023-10-11","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4339,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.26746,"AVALU":"mg/L","BASE2":8.90509,"BASE":9.28699,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.36236,"PCHG2":4.06919,"CHG":-0.01954,"PCHG":-0.21036,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-02 06:37:27","ADY":619,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-5-id-20","SUBJID":"id-20","SITEID":"PAK-5","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-5","INVNAM":"Dr. PAK-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.84789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-20","TRTSDTM":"2020-09-21 06:37:27","TRTEDTM":"2023-09-22 00:37:27","TRT01SDTM":"2020-09-21 06:37:27","TRT01EDTM":"2022-09-21 18:37:27","TRT02SDTM":"2022-09-21 18:37:27","TRT02EDTM":"2023-09-22 00:37:27","AP01SDTM":"2020-09-21 06:37:27","AP01EDTM":"2022-09-21 18:37:27","AP02SDTM":"2022-09-21 18:37:27","AP02EDTM":"2023-09-22 00:37:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-22","EOSDY":1096,"LSTALVDT":"2023-10-11","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1364,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.33862,"AVALU":"mg/L","BASE2":8.90509,"BASE":9.28699,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.43353,"PCHG2":4.86835,"CHG":0.05163,"PCHG":0.55594,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-26 06:37:27","ADY":704,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-5-id-20","SUBJID":"id-20","SITEID":"PAK-5","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-5","INVNAM":"Dr. PAK-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.84789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-20","TRTSDTM":"2020-09-21 06:37:27","TRTEDTM":"2023-09-22 00:37:27","TRT01SDTM":"2020-09-21 06:37:27","TRT01EDTM":"2022-09-21 18:37:27","TRT02SDTM":"2022-09-21 18:37:27","TRT02EDTM":"2023-09-22 00:37:27","AP01SDTM":"2020-09-21 06:37:27","AP01EDTM":"2022-09-21 18:37:27","AP02SDTM":"2022-09-21 18:37:27","AP02EDTM":"2023-09-22 00:37:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-22","EOSDY":1096,"LSTALVDT":"2023-10-11","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3961,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.76052,"AVALU":"mg/L","BASE2":8.90509,"BASE":9.28699,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14457,"PCHG2":-1.62349,"CHG":-0.52647,"PCHG":-5.66894,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-06 06:37:27","ADY":1080,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-5-id-20","SUBJID":"id-20","SITEID":"PAK-5","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-5","INVNAM":"Dr. PAK-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.84789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-20","TRTSDTM":"2020-09-21 06:37:27","TRTEDTM":"2023-09-22 00:37:27","TRT01SDTM":"2020-09-21 06:37:27","TRT01EDTM":"2022-09-21 18:37:27","TRT02SDTM":"2022-09-21 18:37:27","TRT02EDTM":"2023-09-22 00:37:27","AP01SDTM":"2020-09-21 06:37:27","AP01EDTM":"2022-09-21 18:37:27","AP02SDTM":"2022-09-21 18:37:27","AP02EDTM":"2023-09-22 00:37:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-22","EOSDY":1096,"LSTALVDT":"2023-10-11","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2416,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01605,"AVALU":"g/L","BASE2":3.01605,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-10-20 06:37:27","ADY":29,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-5-id-20","SUBJID":"id-20","SITEID":"PAK-5","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-5","INVNAM":"Dr. PAK-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.84789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-20","TRTSDTM":"2020-09-21 06:37:27","TRTEDTM":"2023-09-22 00:37:27","TRT01SDTM":"2020-09-21 06:37:27","TRT01EDTM":"2022-09-21 18:37:27","TRT02SDTM":"2022-09-21 18:37:27","TRT02EDTM":"2023-09-22 00:37:27","AP01SDTM":"2020-09-21 06:37:27","AP01EDTM":"2022-09-21 18:37:27","AP02SDTM":"2022-09-21 18:37:27","AP02EDTM":"2023-09-22 00:37:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-22","EOSDY":1096,"LSTALVDT":"2023-10-11","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":398,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89173,"AVALU":"g/L","BASE2":3.01605,"BASE":2.89173,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.12432,"PCHG2":-4.12209,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-09 06:37:27","ADY":49,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-5-id-20","SUBJID":"id-20","SITEID":"PAK-5","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-5","INVNAM":"Dr. PAK-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.84789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-20","TRTSDTM":"2020-09-21 06:37:27","TRTEDTM":"2023-09-22 00:37:27","TRT01SDTM":"2020-09-21 06:37:27","TRT01EDTM":"2022-09-21 18:37:27","TRT02SDTM":"2022-09-21 18:37:27","TRT02EDTM":"2023-09-22 00:37:27","AP01SDTM":"2020-09-21 06:37:27","AP01EDTM":"2022-09-21 18:37:27","AP02SDTM":"2022-09-21 18:37:27","AP02EDTM":"2023-09-22 00:37:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-22","EOSDY":1096,"LSTALVDT":"2023-10-11","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2151,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95762,"AVALU":"g/L","BASE2":3.01605,"BASE":2.89173,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05844,"PCHG2":-1.93756,"CHG":0.06589,"PCHG":2.27845,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-20 06:37:27","ADY":90,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-5-id-20","SUBJID":"id-20","SITEID":"PAK-5","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-5","INVNAM":"Dr. PAK-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.84789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-20","TRTSDTM":"2020-09-21 06:37:27","TRTEDTM":"2023-09-22 00:37:27","TRT01SDTM":"2020-09-21 06:37:27","TRT01EDTM":"2022-09-21 18:37:27","TRT02SDTM":"2022-09-21 18:37:27","TRT02EDTM":"2023-09-22 00:37:27","AP01SDTM":"2020-09-21 06:37:27","AP01EDTM":"2022-09-21 18:37:27","AP02SDTM":"2022-09-21 18:37:27","AP02EDTM":"2023-09-22 00:37:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-22","EOSDY":1096,"LSTALVDT":"2023-10-11","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3150,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88566,"AVALU":"g/L","BASE2":3.01605,"BASE":2.89173,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13039,"PCHG2":-4.32336,"CHG":-0.00607,"PCHG":-0.20992,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-11 06:37:27","ADY":567,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-5-id-20","SUBJID":"id-20","SITEID":"PAK-5","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-5","INVNAM":"Dr. PAK-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.84789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-20","TRTSDTM":"2020-09-21 06:37:27","TRTEDTM":"2023-09-22 00:37:27","TRT01SDTM":"2020-09-21 06:37:27","TRT01EDTM":"2022-09-21 18:37:27","TRT02SDTM":"2022-09-21 18:37:27","TRT02EDTM":"2023-09-22 00:37:27","AP01SDTM":"2020-09-21 06:37:27","AP01EDTM":"2022-09-21 18:37:27","AP02SDTM":"2022-09-21 18:37:27","AP02EDTM":"2023-09-22 00:37:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-22","EOSDY":1096,"LSTALVDT":"2023-10-11","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6106,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89156,"AVALU":"g/L","BASE2":3.01605,"BASE":2.89173,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1245,"PCHG2":-4.1278,"CHG":-0.00017,"PCHG":-0.00595,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-02 06:37:27","ADY":619,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-5-id-20","SUBJID":"id-20","SITEID":"PAK-5","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-5","INVNAM":"Dr. PAK-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.84789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-20","TRTSDTM":"2020-09-21 06:37:27","TRTEDTM":"2023-09-22 00:37:27","TRT01SDTM":"2020-09-21 06:37:27","TRT01EDTM":"2022-09-21 18:37:27","TRT02SDTM":"2022-09-21 18:37:27","TRT02EDTM":"2023-09-22 00:37:27","AP01SDTM":"2020-09-21 06:37:27","AP01EDTM":"2022-09-21 18:37:27","AP02SDTM":"2022-09-21 18:37:27","AP02EDTM":"2023-09-22 00:37:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-22","EOSDY":1096,"LSTALVDT":"2023-10-11","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6308,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76975,"AVALU":"g/L","BASE2":3.01605,"BASE":2.89173,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.2463,"PCHG2":-8.16637,"CHG":-0.12198,"PCHG":-4.21816,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-26 06:37:27","ADY":704,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-PAK-5-id-20","SUBJID":"id-20","SITEID":"PAK-5","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"PAK","DTHFL":"N","INVID":"INV ID PAK-5","INVNAM":"Dr. PAK-5 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Asia","STRATA1":"A","STRATA2":"S2","BMRKR1":5.84789,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-20","TRTSDTM":"2020-09-21 06:37:27","TRTEDTM":"2023-09-22 00:37:27","TRT01SDTM":"2020-09-21 06:37:27","TRT01EDTM":"2022-09-21 18:37:27","TRT02SDTM":"2022-09-21 18:37:27","TRT02EDTM":"2023-09-22 00:37:27","AP01SDTM":"2020-09-21 06:37:27","AP01EDTM":"2022-09-21 18:37:27","AP02SDTM":"2022-09-21 18:37:27","AP02EDTM":"2023-09-22 00:37:27","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-22","EOSDY":1096,"LSTALVDT":"2023-10-11","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1560,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98731,"AVALU":"g/L","BASE2":3.01605,"BASE":2.89173,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02874,"PCHG2":-0.95294,"CHG":0.09558,"PCHG":3.3054,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-06 06:37:27","ADY":1080,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-1-id-52","SUBJID":"id-52","SITEID":"RUS-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-1","INVNAM":"Dr. RUS-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.20635,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-17","TRTSDTM":"2019-03-18 09:38:55","TRTEDTM":"2022-02-13 12:30:28","TRT01SDTM":"2019-03-18 09:38:55","TRT01EDTM":"2021-02-13 06:30:28","TRT02SDTM":"2021-02-13 06:30:28","TRT02EDTM":"2022-02-13 12:30:28","AP01SDTM":"2019-03-18 09:38:55","AP01EDTM":"2021-02-13 06:30:28","AP02SDTM":"2021-02-13 06:30:28","AP02EDTM":"2022-02-13 12:30:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1064,"DCSREAS":"DEATH","DTHDT":"2022-02-20","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-20","DTHADY":1069,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7745,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.78759,"AVALU":"U/L","BASE2":11.78759,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-08 09:38:55","ADY":265,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-1-id-52","SUBJID":"id-52","SITEID":"RUS-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-1","INVNAM":"Dr. RUS-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.20635,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-17","TRTSDTM":"2019-03-18 09:38:55","TRTEDTM":"2022-02-13 12:30:28","TRT01SDTM":"2019-03-18 09:38:55","TRT01EDTM":"2021-02-13 06:30:28","TRT02SDTM":"2021-02-13 06:30:28","TRT02EDTM":"2022-02-13 12:30:28","AP01SDTM":"2019-03-18 09:38:55","AP01EDTM":"2021-02-13 06:30:28","AP02SDTM":"2021-02-13 06:30:28","AP02EDTM":"2022-02-13 12:30:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1064,"DCSREAS":"DEATH","DTHDT":"2022-02-20","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-20","DTHADY":1069,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2809,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.96012,"AVALU":"U/L","BASE2":11.78759,"BASE":19.96012,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":8.17252,"PCHG2":69.33156,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-05 09:38:55","ADY":293,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-1-id-52","SUBJID":"id-52","SITEID":"RUS-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-1","INVNAM":"Dr. RUS-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.20635,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-17","TRTSDTM":"2019-03-18 09:38:55","TRTEDTM":"2022-02-13 12:30:28","TRT01SDTM":"2019-03-18 09:38:55","TRT01EDTM":"2021-02-13 06:30:28","TRT02SDTM":"2021-02-13 06:30:28","TRT02EDTM":"2022-02-13 12:30:28","AP01SDTM":"2019-03-18 09:38:55","AP01EDTM":"2021-02-13 06:30:28","AP02SDTM":"2021-02-13 06:30:28","AP02EDTM":"2022-02-13 12:30:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1064,"DCSREAS":"DEATH","DTHDT":"2022-02-20","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-20","DTHADY":1069,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4079,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.1817,"AVALU":"U/L","BASE2":11.78759,"BASE":19.96012,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.6059,"PCHG2":-56.04109,"CHG":-14.77842,"PCHG":-74.03974,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-01-16 09:38:55","ADY":304,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-1-id-52","SUBJID":"id-52","SITEID":"RUS-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-1","INVNAM":"Dr. RUS-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.20635,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-17","TRTSDTM":"2019-03-18 09:38:55","TRTEDTM":"2022-02-13 12:30:28","TRT01SDTM":"2019-03-18 09:38:55","TRT01EDTM":"2021-02-13 06:30:28","TRT02SDTM":"2021-02-13 06:30:28","TRT02EDTM":"2022-02-13 12:30:28","AP01SDTM":"2019-03-18 09:38:55","AP01EDTM":"2021-02-13 06:30:28","AP02SDTM":"2021-02-13 06:30:28","AP02EDTM":"2022-02-13 12:30:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1064,"DCSREAS":"DEATH","DTHDT":"2022-02-20","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-20","DTHADY":1069,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":369,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.32446,"AVALU":"U/L","BASE2":11.78759,"BASE":19.96012,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.53687,"PCHG2":97.87296,"CHG":3.36434,"PCHG":16.85533,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-04 09:38:55","ADY":597,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-1-id-52","SUBJID":"id-52","SITEID":"RUS-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-1","INVNAM":"Dr. RUS-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.20635,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-17","TRTSDTM":"2019-03-18 09:38:55","TRTEDTM":"2022-02-13 12:30:28","TRT01SDTM":"2019-03-18 09:38:55","TRT01EDTM":"2021-02-13 06:30:28","TRT02SDTM":"2021-02-13 06:30:28","TRT02EDTM":"2022-02-13 12:30:28","AP01SDTM":"2019-03-18 09:38:55","AP01EDTM":"2021-02-13 06:30:28","AP02SDTM":"2021-02-13 06:30:28","AP02EDTM":"2022-02-13 12:30:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1064,"DCSREAS":"DEATH","DTHDT":"2022-02-20","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-20","DTHADY":1069,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8303,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.54764,"AVALU":"U/L","BASE2":11.78759,"BASE":19.96012,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.76005,"PCHG2":82.79932,"CHG":1.58752,"PCHG":7.95348,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-08 09:38:55","ADY":782,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-1-id-52","SUBJID":"id-52","SITEID":"RUS-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-1","INVNAM":"Dr. RUS-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.20635,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-17","TRTSDTM":"2019-03-18 09:38:55","TRTEDTM":"2022-02-13 12:30:28","TRT01SDTM":"2019-03-18 09:38:55","TRT01EDTM":"2021-02-13 06:30:28","TRT02SDTM":"2021-02-13 06:30:28","TRT02EDTM":"2022-02-13 12:30:28","AP01SDTM":"2019-03-18 09:38:55","AP01EDTM":"2021-02-13 06:30:28","AP02SDTM":"2021-02-13 06:30:28","AP02EDTM":"2022-02-13 12:30:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1064,"DCSREAS":"DEATH","DTHDT":"2022-02-20","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-20","DTHADY":1069,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8222,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.23109,"AVALU":"U/L","BASE2":11.78759,"BASE":19.96012,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.5565,"PCHG2":-64.10553,"CHG":-15.72902,"PCHG":-78.80226,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-10-01 09:38:55","ADY":928,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-1-id-52","SUBJID":"id-52","SITEID":"RUS-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-1","INVNAM":"Dr. RUS-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.20635,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-17","TRTSDTM":"2019-03-18 09:38:55","TRTEDTM":"2022-02-13 12:30:28","TRT01SDTM":"2019-03-18 09:38:55","TRT01EDTM":"2021-02-13 06:30:28","TRT02SDTM":"2021-02-13 06:30:28","TRT02EDTM":"2022-02-13 12:30:28","AP01SDTM":"2019-03-18 09:38:55","AP01EDTM":"2021-02-13 06:30:28","AP02SDTM":"2021-02-13 06:30:28","AP02EDTM":"2022-02-13 12:30:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1064,"DCSREAS":"DEATH","DTHDT":"2022-02-20","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-20","DTHADY":1069,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4931,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.76194,"AVALU":"U/L","BASE2":11.78759,"BASE":19.96012,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.02565,"PCHG2":-51.11861,"CHG":-14.19818,"PCHG":-71.13274,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-12-02 09:38:55","ADY":990,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-1-id-52","SUBJID":"id-52","SITEID":"RUS-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-1","INVNAM":"Dr. RUS-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.20635,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-17","TRTSDTM":"2019-03-18 09:38:55","TRTEDTM":"2022-02-13 12:30:28","TRT01SDTM":"2019-03-18 09:38:55","TRT01EDTM":"2021-02-13 06:30:28","TRT02SDTM":"2021-02-13 06:30:28","TRT02EDTM":"2022-02-13 12:30:28","AP01SDTM":"2019-03-18 09:38:55","AP01EDTM":"2021-02-13 06:30:28","AP02SDTM":"2021-02-13 06:30:28","AP02EDTM":"2022-02-13 12:30:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1064,"DCSREAS":"DEATH","DTHDT":"2022-02-20","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-20","DTHADY":1069,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7857,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.17423,"AVALU":"mg/L","BASE2":8.17423,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-08 09:38:55","ADY":265,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-1-id-52","SUBJID":"id-52","SITEID":"RUS-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-1","INVNAM":"Dr. RUS-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.20635,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-17","TRTSDTM":"2019-03-18 09:38:55","TRTEDTM":"2022-02-13 12:30:28","TRT01SDTM":"2019-03-18 09:38:55","TRT01EDTM":"2021-02-13 06:30:28","TRT02SDTM":"2021-02-13 06:30:28","TRT02EDTM":"2022-02-13 12:30:28","AP01SDTM":"2019-03-18 09:38:55","AP01EDTM":"2021-02-13 06:30:28","AP02SDTM":"2021-02-13 06:30:28","AP02EDTM":"2022-02-13 12:30:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1064,"DCSREAS":"DEATH","DTHDT":"2022-02-20","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-20","DTHADY":1069,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6715,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.52109,"AVALU":"mg/L","BASE2":8.17423,"BASE":8.52109,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.34686,"PCHG2":4.24336,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-05 09:38:55","ADY":293,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-1-id-52","SUBJID":"id-52","SITEID":"RUS-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-1","INVNAM":"Dr. RUS-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.20635,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-17","TRTSDTM":"2019-03-18 09:38:55","TRTEDTM":"2022-02-13 12:30:28","TRT01SDTM":"2019-03-18 09:38:55","TRT01EDTM":"2021-02-13 06:30:28","TRT02SDTM":"2021-02-13 06:30:28","TRT02EDTM":"2022-02-13 12:30:28","AP01SDTM":"2019-03-18 09:38:55","AP01EDTM":"2021-02-13 06:30:28","AP02SDTM":"2021-02-13 06:30:28","AP02EDTM":"2022-02-13 12:30:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1064,"DCSREAS":"DEATH","DTHDT":"2022-02-20","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-20","DTHADY":1069,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7699,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.33159,"AVALU":"mg/L","BASE2":8.17423,"BASE":8.52109,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.15736,"PCHG2":38.62581,"CHG":2.8105,"PCHG":32.98287,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-01-16 09:38:55","ADY":304,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-1-id-52","SUBJID":"id-52","SITEID":"RUS-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-1","INVNAM":"Dr. RUS-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.20635,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-17","TRTSDTM":"2019-03-18 09:38:55","TRTEDTM":"2022-02-13 12:30:28","TRT01SDTM":"2019-03-18 09:38:55","TRT01EDTM":"2021-02-13 06:30:28","TRT02SDTM":"2021-02-13 06:30:28","TRT02EDTM":"2022-02-13 12:30:28","AP01SDTM":"2019-03-18 09:38:55","AP01EDTM":"2021-02-13 06:30:28","AP02SDTM":"2021-02-13 06:30:28","AP02EDTM":"2022-02-13 12:30:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1064,"DCSREAS":"DEATH","DTHDT":"2022-02-20","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-20","DTHADY":1069,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":650,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.59741,"AVALU":"mg/L","BASE2":8.17423,"BASE":8.52109,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.42318,"PCHG2":17.41061,"CHG":1.07632,"PCHG":12.63126,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-04 09:38:55","ADY":597,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-1-id-52","SUBJID":"id-52","SITEID":"RUS-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-1","INVNAM":"Dr. RUS-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.20635,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-17","TRTSDTM":"2019-03-18 09:38:55","TRTEDTM":"2022-02-13 12:30:28","TRT01SDTM":"2019-03-18 09:38:55","TRT01EDTM":"2021-02-13 06:30:28","TRT02SDTM":"2021-02-13 06:30:28","TRT02EDTM":"2022-02-13 12:30:28","AP01SDTM":"2019-03-18 09:38:55","AP01EDTM":"2021-02-13 06:30:28","AP02SDTM":"2021-02-13 06:30:28","AP02EDTM":"2022-02-13 12:30:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1064,"DCSREAS":"DEATH","DTHDT":"2022-02-20","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-20","DTHADY":1069,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1172,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.76135,"AVALU":"mg/L","BASE2":8.17423,"BASE":8.52109,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.58712,"PCHG2":19.41616,"CHG":1.24026,"PCHG":14.55517,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-08 09:38:55","ADY":782,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-1-id-52","SUBJID":"id-52","SITEID":"RUS-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-1","INVNAM":"Dr. RUS-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.20635,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-17","TRTSDTM":"2019-03-18 09:38:55","TRTEDTM":"2022-02-13 12:30:28","TRT01SDTM":"2019-03-18 09:38:55","TRT01EDTM":"2021-02-13 06:30:28","TRT02SDTM":"2021-02-13 06:30:28","TRT02EDTM":"2022-02-13 12:30:28","AP01SDTM":"2019-03-18 09:38:55","AP01EDTM":"2021-02-13 06:30:28","AP02SDTM":"2021-02-13 06:30:28","AP02EDTM":"2022-02-13 12:30:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1064,"DCSREAS":"DEATH","DTHDT":"2022-02-20","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-20","DTHADY":1069,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":722,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.61619,"AVALU":"mg/L","BASE2":8.17423,"BASE":8.52109,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.44196,"PCHG2":5.40676,"CHG":0.0951,"PCHG":1.11604,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-01 09:38:55","ADY":928,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-1-id-52","SUBJID":"id-52","SITEID":"RUS-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-1","INVNAM":"Dr. RUS-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.20635,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-17","TRTSDTM":"2019-03-18 09:38:55","TRTEDTM":"2022-02-13 12:30:28","TRT01SDTM":"2019-03-18 09:38:55","TRT01EDTM":"2021-02-13 06:30:28","TRT02SDTM":"2021-02-13 06:30:28","TRT02EDTM":"2022-02-13 12:30:28","AP01SDTM":"2019-03-18 09:38:55","AP01EDTM":"2021-02-13 06:30:28","AP02SDTM":"2021-02-13 06:30:28","AP02EDTM":"2022-02-13 12:30:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1064,"DCSREAS":"DEATH","DTHDT":"2022-02-20","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-20","DTHADY":1069,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5856,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.08671,"AVALU":"mg/L","BASE2":8.17423,"BASE":8.52109,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08751,"PCHG2":-1.07058,"CHG":-0.43437,"PCHG":-5.09763,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-02 09:38:55","ADY":990,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-1-id-52","SUBJID":"id-52","SITEID":"RUS-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-1","INVNAM":"Dr. RUS-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.20635,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-17","TRTSDTM":"2019-03-18 09:38:55","TRTEDTM":"2022-02-13 12:30:28","TRT01SDTM":"2019-03-18 09:38:55","TRT01EDTM":"2021-02-13 06:30:28","TRT02SDTM":"2021-02-13 06:30:28","TRT02EDTM":"2022-02-13 12:30:28","AP01SDTM":"2019-03-18 09:38:55","AP01EDTM":"2021-02-13 06:30:28","AP02SDTM":"2021-02-13 06:30:28","AP02EDTM":"2022-02-13 12:30:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1064,"DCSREAS":"DEATH","DTHDT":"2022-02-20","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-20","DTHADY":1069,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":334,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86306,"AVALU":"g/L","BASE2":2.86306,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2019-12-08 09:38:55","ADY":265,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-1-id-52","SUBJID":"id-52","SITEID":"RUS-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-1","INVNAM":"Dr. RUS-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.20635,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-17","TRTSDTM":"2019-03-18 09:38:55","TRTEDTM":"2022-02-13 12:30:28","TRT01SDTM":"2019-03-18 09:38:55","TRT01EDTM":"2021-02-13 06:30:28","TRT02SDTM":"2021-02-13 06:30:28","TRT02EDTM":"2022-02-13 12:30:28","AP01SDTM":"2019-03-18 09:38:55","AP01EDTM":"2021-02-13 06:30:28","AP02SDTM":"2021-02-13 06:30:28","AP02EDTM":"2022-02-13 12:30:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1064,"DCSREAS":"DEATH","DTHDT":"2022-02-20","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-20","DTHADY":1069,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2331,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01392,"AVALU":"g/L","BASE2":2.86306,"BASE":3.01392,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.15087,"PCHG2":5.26944,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-01-05 09:38:55","ADY":293,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-1-id-52","SUBJID":"id-52","SITEID":"RUS-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-1","INVNAM":"Dr. RUS-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.20635,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-17","TRTSDTM":"2019-03-18 09:38:55","TRTEDTM":"2022-02-13 12:30:28","TRT01SDTM":"2019-03-18 09:38:55","TRT01EDTM":"2021-02-13 06:30:28","TRT02SDTM":"2021-02-13 06:30:28","TRT02EDTM":"2022-02-13 12:30:28","AP01SDTM":"2019-03-18 09:38:55","AP01EDTM":"2021-02-13 06:30:28","AP02SDTM":"2021-02-13 06:30:28","AP02EDTM":"2022-02-13 12:30:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1064,"DCSREAS":"DEATH","DTHDT":"2022-02-20","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-20","DTHADY":1069,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4129,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87154,"AVALU":"g/L","BASE2":2.86306,"BASE":3.01392,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00849,"PCHG2":0.29638,"CHG":-0.14238,"PCHG":-4.72413,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-01-16 09:38:55","ADY":304,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-1-id-52","SUBJID":"id-52","SITEID":"RUS-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-1","INVNAM":"Dr. RUS-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.20635,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-17","TRTSDTM":"2019-03-18 09:38:55","TRTEDTM":"2022-02-13 12:30:28","TRT01SDTM":"2019-03-18 09:38:55","TRT01EDTM":"2021-02-13 06:30:28","TRT02SDTM":"2021-02-13 06:30:28","TRT02EDTM":"2022-02-13 12:30:28","AP01SDTM":"2019-03-18 09:38:55","AP01EDTM":"2021-02-13 06:30:28","AP02SDTM":"2021-02-13 06:30:28","AP02EDTM":"2022-02-13 12:30:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1064,"DCSREAS":"DEATH","DTHDT":"2022-02-20","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-20","DTHADY":1069,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7764,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78195,"AVALU":"g/L","BASE2":2.86306,"BASE":3.01392,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0811,"PCHG2":-2.83276,"CHG":-0.23197,"PCHG":-7.69664,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-11-04 09:38:55","ADY":597,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-1-id-52","SUBJID":"id-52","SITEID":"RUS-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-1","INVNAM":"Dr. RUS-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.20635,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-17","TRTSDTM":"2019-03-18 09:38:55","TRTEDTM":"2022-02-13 12:30:28","TRT01SDTM":"2019-03-18 09:38:55","TRT01EDTM":"2021-02-13 06:30:28","TRT02SDTM":"2021-02-13 06:30:28","TRT02EDTM":"2022-02-13 12:30:28","AP01SDTM":"2019-03-18 09:38:55","AP01EDTM":"2021-02-13 06:30:28","AP02SDTM":"2021-02-13 06:30:28","AP02EDTM":"2022-02-13 12:30:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1064,"DCSREAS":"DEATH","DTHDT":"2022-02-20","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-20","DTHADY":1069,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8308,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78736,"AVALU":"g/L","BASE2":2.86306,"BASE":3.01392,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0757,"PCHG2":-2.64393,"CHG":-0.22656,"PCHG":-7.51726,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-05-08 09:38:55","ADY":782,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-1-id-52","SUBJID":"id-52","SITEID":"RUS-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-1","INVNAM":"Dr. RUS-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.20635,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-17","TRTSDTM":"2019-03-18 09:38:55","TRTEDTM":"2022-02-13 12:30:28","TRT01SDTM":"2019-03-18 09:38:55","TRT01EDTM":"2021-02-13 06:30:28","TRT02SDTM":"2021-02-13 06:30:28","TRT02EDTM":"2022-02-13 12:30:28","AP01SDTM":"2019-03-18 09:38:55","AP01EDTM":"2021-02-13 06:30:28","AP02SDTM":"2021-02-13 06:30:28","AP02EDTM":"2022-02-13 12:30:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1064,"DCSREAS":"DEATH","DTHDT":"2022-02-20","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-20","DTHADY":1069,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1100,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.62834,"AVALU":"g/L","BASE2":2.86306,"BASE":3.01392,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.23471,"PCHG2":-8.19799,"CHG":-0.38558,"PCHG":-12.7933,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-10-01 09:38:55","ADY":928,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-1-id-52","SUBJID":"id-52","SITEID":"RUS-1","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-1","INVNAM":"Dr. RUS-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":7.20635,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-17","TRTSDTM":"2019-03-18 09:38:55","TRTEDTM":"2022-02-13 12:30:28","TRT01SDTM":"2019-03-18 09:38:55","TRT01EDTM":"2021-02-13 06:30:28","TRT02SDTM":"2021-02-13 06:30:28","TRT02EDTM":"2022-02-13 12:30:28","AP01SDTM":"2019-03-18 09:38:55","AP01EDTM":"2021-02-13 06:30:28","AP02SDTM":"2021-02-13 06:30:28","AP02EDTM":"2022-02-13 12:30:28","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":1064,"DCSREAS":"DEATH","DTHDT":"2022-02-20","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":7,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-20","DTHADY":1069,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6945,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84843,"AVALU":"g/L","BASE2":2.86306,"BASE":3.01392,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01463,"PCHG2":-0.51097,"CHG":-0.1655,"PCHG":-5.49106,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-12-02 09:38:55","ADY":990,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-162","SUBJID":"id-162","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":8.34705,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-30","TRTSDTM":"2020-03-30 21:19:53","TRTEDTM":"2022-02-13 14:07:21","TRT01SDTM":"2020-03-30 21:19:53","TRT01EDTM":"2021-02-13 08:07:21","TRT02SDTM":"2021-02-13 08:07:21","TRT02EDTM":"2022-02-13 14:07:21","AP01SDTM":"2020-03-30 21:19:53","AP01EDTM":"2021-02-13 08:07:21","AP02SDTM":"2021-02-13 08:07:21","AP02EDTM":"2022-02-13 14:07:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":685,"DCSREAS":"DEATH","DTHDT":"2022-03-29","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-03-29","DTHADY":728,"ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7766,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.59518,"AVALU":"U/L","BASE2":11.59518,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-24 21:19:53","ADY":178,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-162","SUBJID":"id-162","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":8.34705,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-30","TRTSDTM":"2020-03-30 21:19:53","TRTEDTM":"2022-02-13 14:07:21","TRT01SDTM":"2020-03-30 21:19:53","TRT01EDTM":"2021-02-13 08:07:21","TRT02SDTM":"2021-02-13 08:07:21","TRT02EDTM":"2022-02-13 14:07:21","AP01SDTM":"2020-03-30 21:19:53","AP01EDTM":"2021-02-13 08:07:21","AP02SDTM":"2021-02-13 08:07:21","AP02EDTM":"2022-02-13 14:07:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":685,"DCSREAS":"DEATH","DTHDT":"2022-03-29","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-03-29","DTHADY":728,"ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7663,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":39.89456,"AVALU":"U/L","BASE2":11.59518,"BASE":39.89456,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":28.29938,"PCHG2":244.0615,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-07 21:19:53","ADY":191,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-162","SUBJID":"id-162","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":8.34705,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-30","TRTSDTM":"2020-03-30 21:19:53","TRTEDTM":"2022-02-13 14:07:21","TRT01SDTM":"2020-03-30 21:19:53","TRT01EDTM":"2021-02-13 08:07:21","TRT02SDTM":"2021-02-13 08:07:21","TRT02EDTM":"2022-02-13 14:07:21","AP01SDTM":"2020-03-30 21:19:53","AP01EDTM":"2021-02-13 08:07:21","AP02SDTM":"2021-02-13 08:07:21","AP02EDTM":"2022-02-13 14:07:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":685,"DCSREAS":"DEATH","DTHDT":"2022-03-29","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-03-29","DTHADY":728,"ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2979,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.86891,"AVALU":"U/L","BASE2":11.59518,"BASE":39.89456,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.27373,"PCHG2":123.10049,"CHG":-14.02565,"PCHG":-35.1568,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-25 21:19:53","ADY":240,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-162","SUBJID":"id-162","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":8.34705,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-30","TRTSDTM":"2020-03-30 21:19:53","TRTEDTM":"2022-02-13 14:07:21","TRT01SDTM":"2020-03-30 21:19:53","TRT01EDTM":"2021-02-13 08:07:21","TRT02SDTM":"2021-02-13 08:07:21","TRT02EDTM":"2022-02-13 14:07:21","AP01SDTM":"2020-03-30 21:19:53","AP01EDTM":"2021-02-13 08:07:21","AP02SDTM":"2021-02-13 08:07:21","AP02EDTM":"2022-02-13 14:07:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":685,"DCSREAS":"DEATH","DTHDT":"2022-03-29","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-03-29","DTHADY":728,"ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1670,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.68999,"AVALU":"U/L","BASE2":11.59518,"BASE":39.89456,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":20.0948,"PCHG2":173.30304,"CHG":-8.20457,"PCHG":-20.56564,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-27 21:19:53","ADY":303,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-162","SUBJID":"id-162","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":8.34705,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-30","TRTSDTM":"2020-03-30 21:19:53","TRTEDTM":"2022-02-13 14:07:21","TRT01SDTM":"2020-03-30 21:19:53","TRT01EDTM":"2021-02-13 08:07:21","TRT02SDTM":"2021-02-13 08:07:21","TRT02EDTM":"2022-02-13 14:07:21","AP01SDTM":"2020-03-30 21:19:53","AP01EDTM":"2021-02-13 08:07:21","AP02SDTM":"2021-02-13 08:07:21","AP02EDTM":"2022-02-13 14:07:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":685,"DCSREAS":"DEATH","DTHDT":"2022-03-29","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-03-29","DTHADY":728,"ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2937,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.57374,"AVALU":"U/L","BASE2":11.59518,"BASE":39.89456,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.97856,"PCHG2":34.31217,"CHG":-24.32082,"PCHG":-60.96274,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-21 21:19:53","ADY":356,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-162","SUBJID":"id-162","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":8.34705,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-30","TRTSDTM":"2020-03-30 21:19:53","TRTEDTM":"2022-02-13 14:07:21","TRT01SDTM":"2020-03-30 21:19:53","TRT01EDTM":"2021-02-13 08:07:21","TRT02SDTM":"2021-02-13 08:07:21","TRT02EDTM":"2022-02-13 14:07:21","AP01SDTM":"2020-03-30 21:19:53","AP01EDTM":"2021-02-13 08:07:21","AP02SDTM":"2021-02-13 08:07:21","AP02EDTM":"2022-02-13 14:07:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":685,"DCSREAS":"DEATH","DTHDT":"2022-03-29","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-03-29","DTHADY":728,"ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1744,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.72389,"AVALU":"U/L","BASE2":11.59518,"BASE":39.89456,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.1287,"PCHG2":52.85559,"CHG":-22.17067,"PCHG":-55.57318,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-12 21:19:53","ADY":439,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-162","SUBJID":"id-162","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":8.34705,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-30","TRTSDTM":"2020-03-30 21:19:53","TRTEDTM":"2022-02-13 14:07:21","TRT01SDTM":"2020-03-30 21:19:53","TRT01EDTM":"2021-02-13 08:07:21","TRT02SDTM":"2021-02-13 08:07:21","TRT02EDTM":"2022-02-13 14:07:21","AP01SDTM":"2020-03-30 21:19:53","AP01EDTM":"2021-02-13 08:07:21","AP02SDTM":"2021-02-13 08:07:21","AP02EDTM":"2022-02-13 14:07:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":685,"DCSREAS":"DEATH","DTHDT":"2022-03-29","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-03-29","DTHADY":728,"ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1385,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.98218,"AVALU":"U/L","BASE2":11.59518,"BASE":39.89456,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.387,"PCHG2":132.70167,"CHG":-12.91238,"PCHG":-32.36626,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-07 21:19:53","ADY":495,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-162","SUBJID":"id-162","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":8.34705,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-30","TRTSDTM":"2020-03-30 21:19:53","TRTEDTM":"2022-02-13 14:07:21","TRT01SDTM":"2020-03-30 21:19:53","TRT01EDTM":"2021-02-13 08:07:21","TRT02SDTM":"2021-02-13 08:07:21","TRT02EDTM":"2022-02-13 14:07:21","AP01SDTM":"2020-03-30 21:19:53","AP01EDTM":"2021-02-13 08:07:21","AP02SDTM":"2021-02-13 08:07:21","AP02EDTM":"2022-02-13 14:07:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":685,"DCSREAS":"DEATH","DTHDT":"2022-03-29","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-03-29","DTHADY":728,"ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4435,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.4512,"AVALU":"mg/L","BASE2":7.4512,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-3","ADTM":"2020-09-24 21:19:53","ADY":178,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-162","SUBJID":"id-162","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":8.34705,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-30","TRTSDTM":"2020-03-30 21:19:53","TRTEDTM":"2022-02-13 14:07:21","TRT01SDTM":"2020-03-30 21:19:53","TRT01EDTM":"2021-02-13 08:07:21","TRT02SDTM":"2021-02-13 08:07:21","TRT02EDTM":"2022-02-13 14:07:21","AP01SDTM":"2020-03-30 21:19:53","AP01EDTM":"2021-02-13 08:07:21","AP02SDTM":"2021-02-13 08:07:21","AP02EDTM":"2022-02-13 14:07:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":685,"DCSREAS":"DEATH","DTHDT":"2022-03-29","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-03-29","DTHADY":728,"ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6879,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.6796,"AVALU":"mg/L","BASE2":7.4512,"BASE":7.6796,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.2284,"PCHG2":3.06522,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2020-10-07 21:19:53","ADY":191,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-162","SUBJID":"id-162","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":8.34705,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-30","TRTSDTM":"2020-03-30 21:19:53","TRTEDTM":"2022-02-13 14:07:21","TRT01SDTM":"2020-03-30 21:19:53","TRT01EDTM":"2021-02-13 08:07:21","TRT02SDTM":"2021-02-13 08:07:21","TRT02EDTM":"2022-02-13 14:07:21","AP01SDTM":"2020-03-30 21:19:53","AP01EDTM":"2021-02-13 08:07:21","AP02SDTM":"2021-02-13 08:07:21","AP02EDTM":"2022-02-13 14:07:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":685,"DCSREAS":"DEATH","DTHDT":"2022-03-29","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-03-29","DTHADY":728,"ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7434,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.92016,"AVALU":"mg/L","BASE2":7.4512,"BASE":7.6796,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.46895,"PCHG2":19.71432,"CHG":1.24056,"PCHG":16.15394,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2020-11-25 21:19:53","ADY":240,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-162","SUBJID":"id-162","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":8.34705,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-30","TRTSDTM":"2020-03-30 21:19:53","TRTEDTM":"2022-02-13 14:07:21","TRT01SDTM":"2020-03-30 21:19:53","TRT01EDTM":"2021-02-13 08:07:21","TRT02SDTM":"2021-02-13 08:07:21","TRT02EDTM":"2022-02-13 14:07:21","AP01SDTM":"2020-03-30 21:19:53","AP01EDTM":"2021-02-13 08:07:21","AP02SDTM":"2021-02-13 08:07:21","AP02EDTM":"2022-02-13 14:07:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":685,"DCSREAS":"DEATH","DTHDT":"2022-03-29","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-03-29","DTHADY":728,"ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2860,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.39483,"AVALU":"mg/L","BASE2":7.4512,"BASE":7.6796,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.94363,"PCHG2":26.08473,"CHG":1.71523,"PCHG":22.33489,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-01-27 21:19:53","ADY":303,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-162","SUBJID":"id-162","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":8.34705,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-30","TRTSDTM":"2020-03-30 21:19:53","TRTEDTM":"2022-02-13 14:07:21","TRT01SDTM":"2020-03-30 21:19:53","TRT01EDTM":"2021-02-13 08:07:21","TRT02SDTM":"2021-02-13 08:07:21","TRT02EDTM":"2022-02-13 14:07:21","AP01SDTM":"2020-03-30 21:19:53","AP01EDTM":"2021-02-13 08:07:21","AP02SDTM":"2021-02-13 08:07:21","AP02EDTM":"2022-02-13 14:07:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":685,"DCSREAS":"DEATH","DTHDT":"2022-03-29","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-03-29","DTHADY":728,"ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1810,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.17828,"AVALU":"mg/L","BASE2":7.4512,"BASE":7.6796,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.72707,"PCHG2":9.75776,"CHG":0.49867,"PCHG":6.4935,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-03-21 21:19:53","ADY":356,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-162","SUBJID":"id-162","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":8.34705,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-30","TRTSDTM":"2020-03-30 21:19:53","TRTEDTM":"2022-02-13 14:07:21","TRT01SDTM":"2020-03-30 21:19:53","TRT01EDTM":"2021-02-13 08:07:21","TRT02SDTM":"2021-02-13 08:07:21","TRT02EDTM":"2022-02-13 14:07:21","AP01SDTM":"2020-03-30 21:19:53","AP01EDTM":"2021-02-13 08:07:21","AP02SDTM":"2021-02-13 08:07:21","AP02EDTM":"2022-02-13 14:07:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":685,"DCSREAS":"DEATH","DTHDT":"2022-03-29","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-03-29","DTHADY":728,"ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2072,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.06439,"AVALU":"mg/L","BASE2":7.4512,"BASE":7.6796,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.61318,"PCHG2":8.2293,"CHG":0.38479,"PCHG":5.01049,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-06-12 21:19:53","ADY":439,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-162","SUBJID":"id-162","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":8.34705,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-30","TRTSDTM":"2020-03-30 21:19:53","TRTEDTM":"2022-02-13 14:07:21","TRT01SDTM":"2020-03-30 21:19:53","TRT01EDTM":"2021-02-13 08:07:21","TRT02SDTM":"2021-02-13 08:07:21","TRT02EDTM":"2022-02-13 14:07:21","AP01SDTM":"2020-03-30 21:19:53","AP01EDTM":"2021-02-13 08:07:21","AP02SDTM":"2021-02-13 08:07:21","AP02EDTM":"2022-02-13 14:07:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":685,"DCSREAS":"DEATH","DTHDT":"2022-03-29","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-03-29","DTHADY":728,"ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":263,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.07639,"AVALU":"mg/L","BASE2":7.4512,"BASE":7.6796,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.62519,"PCHG2":8.39043,"CHG":0.39679,"PCHG":5.16683,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-08-07 21:19:53","ADY":495,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-162","SUBJID":"id-162","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":8.34705,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-30","TRTSDTM":"2020-03-30 21:19:53","TRTEDTM":"2022-02-13 14:07:21","TRT01SDTM":"2020-03-30 21:19:53","TRT01EDTM":"2021-02-13 08:07:21","TRT02SDTM":"2021-02-13 08:07:21","TRT02EDTM":"2022-02-13 14:07:21","AP01SDTM":"2020-03-30 21:19:53","AP01EDTM":"2021-02-13 08:07:21","AP02SDTM":"2021-02-13 08:07:21","AP02EDTM":"2022-02-13 14:07:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":685,"DCSREAS":"DEATH","DTHDT":"2022-03-29","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-03-29","DTHADY":728,"ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4673,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86555,"AVALU":"g/L","BASE2":2.86555,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-24 21:19:53","ADY":178,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-162","SUBJID":"id-162","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":8.34705,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-30","TRTSDTM":"2020-03-30 21:19:53","TRTEDTM":"2022-02-13 14:07:21","TRT01SDTM":"2020-03-30 21:19:53","TRT01EDTM":"2021-02-13 08:07:21","TRT02SDTM":"2021-02-13 08:07:21","TRT02EDTM":"2022-02-13 14:07:21","AP01SDTM":"2020-03-30 21:19:53","AP01EDTM":"2021-02-13 08:07:21","AP02SDTM":"2021-02-13 08:07:21","AP02EDTM":"2022-02-13 14:07:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":685,"DCSREAS":"DEATH","DTHDT":"2022-03-29","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-03-29","DTHADY":728,"ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4611,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81831,"AVALU":"g/L","BASE2":2.86555,"BASE":2.81831,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.04724,"PCHG2":-1.64859,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-07 21:19:53","ADY":191,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-162","SUBJID":"id-162","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":8.34705,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-30","TRTSDTM":"2020-03-30 21:19:53","TRTEDTM":"2022-02-13 14:07:21","TRT01SDTM":"2020-03-30 21:19:53","TRT01EDTM":"2021-02-13 08:07:21","TRT02SDTM":"2021-02-13 08:07:21","TRT02EDTM":"2022-02-13 14:07:21","AP01SDTM":"2020-03-30 21:19:53","AP01EDTM":"2021-02-13 08:07:21","AP02SDTM":"2021-02-13 08:07:21","AP02EDTM":"2022-02-13 14:07:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":685,"DCSREAS":"DEATH","DTHDT":"2022-03-29","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-03-29","DTHADY":728,"ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7232,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95831,"AVALU":"g/L","BASE2":2.86555,"BASE":2.81831,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09275,"PCHG2":3.23681,"CHG":0.13999,"PCHG":4.96729,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-25 21:19:53","ADY":240,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-162","SUBJID":"id-162","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":8.34705,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-30","TRTSDTM":"2020-03-30 21:19:53","TRTEDTM":"2022-02-13 14:07:21","TRT01SDTM":"2020-03-30 21:19:53","TRT01EDTM":"2021-02-13 08:07:21","TRT02SDTM":"2021-02-13 08:07:21","TRT02EDTM":"2022-02-13 14:07:21","AP01SDTM":"2020-03-30 21:19:53","AP01EDTM":"2021-02-13 08:07:21","AP02SDTM":"2021-02-13 08:07:21","AP02EDTM":"2022-02-13 14:07:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":685,"DCSREAS":"DEATH","DTHDT":"2022-03-29","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-03-29","DTHADY":728,"ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":664,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93162,"AVALU":"g/L","BASE2":2.86555,"BASE":2.81831,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06607,"PCHG2":2.3055,"CHG":0.11331,"PCHG":4.02037,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-27 21:19:53","ADY":303,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-162","SUBJID":"id-162","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":8.34705,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-30","TRTSDTM":"2020-03-30 21:19:53","TRTEDTM":"2022-02-13 14:07:21","TRT01SDTM":"2020-03-30 21:19:53","TRT01EDTM":"2021-02-13 08:07:21","TRT02SDTM":"2021-02-13 08:07:21","TRT02EDTM":"2022-02-13 14:07:21","AP01SDTM":"2020-03-30 21:19:53","AP01EDTM":"2021-02-13 08:07:21","AP02SDTM":"2021-02-13 08:07:21","AP02EDTM":"2022-02-13 14:07:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":685,"DCSREAS":"DEATH","DTHDT":"2022-03-29","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-03-29","DTHADY":728,"ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":181,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00689,"AVALU":"g/L","BASE2":2.86555,"BASE":2.81831,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14134,"PCHG2":4.93242,"CHG":0.18858,"PCHG":6.69132,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-03-21 21:19:53","ADY":356,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-162","SUBJID":"id-162","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":8.34705,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-30","TRTSDTM":"2020-03-30 21:19:53","TRTEDTM":"2022-02-13 14:07:21","TRT01SDTM":"2020-03-30 21:19:53","TRT01EDTM":"2021-02-13 08:07:21","TRT02SDTM":"2021-02-13 08:07:21","TRT02EDTM":"2022-02-13 14:07:21","AP01SDTM":"2020-03-30 21:19:53","AP01EDTM":"2021-02-13 08:07:21","AP02SDTM":"2021-02-13 08:07:21","AP02EDTM":"2022-02-13 14:07:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":685,"DCSREAS":"DEATH","DTHDT":"2022-03-29","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-03-29","DTHADY":728,"ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5660,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77839,"AVALU":"g/L","BASE2":2.86555,"BASE":2.81831,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08717,"PCHG2":-3.04187,"CHG":-0.03993,"PCHG":-1.41664,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-12 21:19:53","ADY":439,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-162","SUBJID":"id-162","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":8.34705,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-30","TRTSDTM":"2020-03-30 21:19:53","TRTEDTM":"2022-02-13 14:07:21","TRT01SDTM":"2020-03-30 21:19:53","TRT01EDTM":"2021-02-13 08:07:21","TRT02SDTM":"2021-02-13 08:07:21","TRT02EDTM":"2022-02-13 14:07:21","AP01SDTM":"2020-03-30 21:19:53","AP01EDTM":"2021-02-13 08:07:21","AP02SDTM":"2021-02-13 08:07:21","AP02EDTM":"2022-02-13 14:07:21","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":685,"DCSREAS":"DEATH","DTHDT":"2022-03-29","DTHCAUS":"LOST TO FOLLOW UP","DTHCAT":"OTHER","LDDTHELD":44,"LDDTHGR1":">30","LSTALVDT":"2022-03-29","DTHADY":728,"ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7956,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89319,"AVALU":"g/L","BASE2":2.86555,"BASE":2.81831,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02764,"PCHG2":0.9644,"CHG":0.07488,"PCHG":2.65679,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-07 21:19:53","ADY":495,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-283","SUBJID":"id-283","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.78881,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-23 11:49:14","TRTEDTM":"2023-07-24 05:49:14","TRT01SDTM":"2020-07-23 11:49:14","TRT01EDTM":"2022-07-23 23:49:14","TRT02SDTM":"2022-07-23 23:49:14","TRT02EDTM":"2023-07-24 05:49:14","AP01SDTM":"2020-07-23 11:49:14","AP01EDTM":"2022-07-23 23:49:14","AP02SDTM":"2022-07-23 23:49:14","AP02EDTM":"2023-07-24 05:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":842,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.19386,"AVALU":"U/L","BASE2":12.19386,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-07 11:49:14","ADY":15,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-283","SUBJID":"id-283","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.78881,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-23 11:49:14","TRTEDTM":"2023-07-24 05:49:14","TRT01SDTM":"2020-07-23 11:49:14","TRT01EDTM":"2022-07-23 23:49:14","TRT02SDTM":"2022-07-23 23:49:14","TRT02EDTM":"2023-07-24 05:49:14","AP01SDTM":"2020-07-23 11:49:14","AP01EDTM":"2022-07-23 23:49:14","AP02SDTM":"2022-07-23 23:49:14","AP02EDTM":"2023-07-24 05:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7734,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.58398,"AVALU":"U/L","BASE2":12.19386,"BASE":25.58398,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":13.39012,"PCHG2":109.81036,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-23 11:49:14","ADY":153,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-283","SUBJID":"id-283","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.78881,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-23 11:49:14","TRTEDTM":"2023-07-24 05:49:14","TRT01SDTM":"2020-07-23 11:49:14","TRT01EDTM":"2022-07-23 23:49:14","TRT02SDTM":"2022-07-23 23:49:14","TRT02EDTM":"2023-07-24 05:49:14","AP01SDTM":"2020-07-23 11:49:14","AP01EDTM":"2022-07-23 23:49:14","AP02SDTM":"2022-07-23 23:49:14","AP02EDTM":"2023-07-24 05:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":418,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.40113,"AVALU":"U/L","BASE2":12.19386,"BASE":25.58398,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.20727,"PCHG2":1.69981,"CHG":-13.18285,"PCHG":-51.52775,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-14 11:49:14","ADY":509,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-283","SUBJID":"id-283","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.78881,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-23 11:49:14","TRTEDTM":"2023-07-24 05:49:14","TRT01SDTM":"2020-07-23 11:49:14","TRT01EDTM":"2022-07-23 23:49:14","TRT02SDTM":"2022-07-23 23:49:14","TRT02EDTM":"2023-07-24 05:49:14","AP01SDTM":"2020-07-23 11:49:14","AP01EDTM":"2022-07-23 23:49:14","AP02SDTM":"2022-07-23 23:49:14","AP02EDTM":"2023-07-24 05:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1673,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.51236,"AVALU":"U/L","BASE2":12.19386,"BASE":25.58398,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.6815,"PCHG2":-54.79394,"CHG":-20.07161,"PCHG":-78.45385,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-07-12 11:49:14","ADY":719,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-283","SUBJID":"id-283","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.78881,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-23 11:49:14","TRTEDTM":"2023-07-24 05:49:14","TRT01SDTM":"2020-07-23 11:49:14","TRT01EDTM":"2022-07-23 23:49:14","TRT02SDTM":"2022-07-23 23:49:14","TRT02EDTM":"2023-07-24 05:49:14","AP01SDTM":"2020-07-23 11:49:14","AP01EDTM":"2022-07-23 23:49:14","AP02SDTM":"2022-07-23 23:49:14","AP02EDTM":"2023-07-24 05:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":837,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.6961,"AVALU":"U/L","BASE2":12.19386,"BASE":25.58398,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.49775,"PCHG2":-36.88539,"CHG":-17.88787,"PCHG":-69.91826,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-30 11:49:14","ADY":860,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-283","SUBJID":"id-283","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.78881,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-23 11:49:14","TRTEDTM":"2023-07-24 05:49:14","TRT01SDTM":"2020-07-23 11:49:14","TRT01EDTM":"2022-07-23 23:49:14","TRT02SDTM":"2022-07-23 23:49:14","TRT02EDTM":"2023-07-24 05:49:14","AP01SDTM":"2020-07-23 11:49:14","AP01EDTM":"2022-07-23 23:49:14","AP02SDTM":"2022-07-23 23:49:14","AP02EDTM":"2023-07-24 05:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":971,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.13473,"AVALU":"U/L","BASE2":12.19386,"BASE":25.58398,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.05913,"PCHG2":-82.49338,"CHG":-23.44924,"PCHG":-91.65598,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2023-01-04 11:49:14","ADY":895,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-283","SUBJID":"id-283","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.78881,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-23 11:49:14","TRTEDTM":"2023-07-24 05:49:14","TRT01SDTM":"2020-07-23 11:49:14","TRT01EDTM":"2022-07-23 23:49:14","TRT02SDTM":"2022-07-23 23:49:14","TRT02EDTM":"2023-07-24 05:49:14","AP01SDTM":"2020-07-23 11:49:14","AP01EDTM":"2022-07-23 23:49:14","AP02SDTM":"2022-07-23 23:49:14","AP02EDTM":"2023-07-24 05:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1796,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.47046,"AVALU":"U/L","BASE2":12.19386,"BASE":25.58398,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.2766,"PCHG2":10.46922,"CHG":-12.11352,"PCHG":-47.34806,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-17 11:49:14","ADY":1059,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-283","SUBJID":"id-283","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.78881,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-23 11:49:14","TRTEDTM":"2023-07-24 05:49:14","TRT01SDTM":"2020-07-23 11:49:14","TRT01EDTM":"2022-07-23 23:49:14","TRT02SDTM":"2022-07-23 23:49:14","TRT02EDTM":"2023-07-24 05:49:14","AP01SDTM":"2020-07-23 11:49:14","AP01EDTM":"2022-07-23 23:49:14","AP02SDTM":"2022-07-23 23:49:14","AP02EDTM":"2023-07-24 05:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3097,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.26991,"AVALU":"mg/L","BASE2":7.26991,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-08-07 11:49:14","ADY":15,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-283","SUBJID":"id-283","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.78881,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-23 11:49:14","TRTEDTM":"2023-07-24 05:49:14","TRT01SDTM":"2020-07-23 11:49:14","TRT01EDTM":"2022-07-23 23:49:14","TRT02SDTM":"2022-07-23 23:49:14","TRT02EDTM":"2023-07-24 05:49:14","AP01SDTM":"2020-07-23 11:49:14","AP01EDTM":"2022-07-23 23:49:14","AP02SDTM":"2022-07-23 23:49:14","AP02EDTM":"2023-07-24 05:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1820,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.3065,"AVALU":"mg/L","BASE2":7.26991,"BASE":8.3065,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.03658,"PCHG2":14.25851,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-23 11:49:14","ADY":153,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-283","SUBJID":"id-283","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.78881,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-23 11:49:14","TRTEDTM":"2023-07-24 05:49:14","TRT01SDTM":"2020-07-23 11:49:14","TRT01EDTM":"2022-07-23 23:49:14","TRT02SDTM":"2022-07-23 23:49:14","TRT02EDTM":"2023-07-24 05:49:14","AP01SDTM":"2020-07-23 11:49:14","AP01EDTM":"2022-07-23 23:49:14","AP02SDTM":"2022-07-23 23:49:14","AP02EDTM":"2023-07-24 05:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":827,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.60569,"AVALU":"mg/L","BASE2":7.26991,"BASE":8.3065,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.33578,"PCHG2":32.12934,"CHG":1.29919,"PCHG":15.6407,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-14 11:49:14","ADY":509,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-283","SUBJID":"id-283","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.78881,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-23 11:49:14","TRTEDTM":"2023-07-24 05:49:14","TRT01SDTM":"2020-07-23 11:49:14","TRT01EDTM":"2022-07-23 23:49:14","TRT02SDTM":"2022-07-23 23:49:14","TRT02EDTM":"2023-07-24 05:49:14","AP01SDTM":"2020-07-23 11:49:14","AP01EDTM":"2022-07-23 23:49:14","AP02SDTM":"2022-07-23 23:49:14","AP02EDTM":"2023-07-24 05:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1412,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.58874,"AVALU":"mg/L","BASE2":7.26991,"BASE":8.3065,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.31883,"PCHG2":31.8962,"CHG":1.28225,"PCHG":15.43666,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-12 11:49:14","ADY":719,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-283","SUBJID":"id-283","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.78881,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-23 11:49:14","TRTEDTM":"2023-07-24 05:49:14","TRT01SDTM":"2020-07-23 11:49:14","TRT01EDTM":"2022-07-23 23:49:14","TRT02SDTM":"2022-07-23 23:49:14","TRT02EDTM":"2023-07-24 05:49:14","AP01SDTM":"2020-07-23 11:49:14","AP01EDTM":"2022-07-23 23:49:14","AP02SDTM":"2022-07-23 23:49:14","AP02EDTM":"2023-07-24 05:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7741,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.46827,"AVALU":"mg/L","BASE2":7.26991,"BASE":8.3065,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.19835,"PCHG2":43.99435,"CHG":2.16177,"PCHG":26.02506,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-11-30 11:49:14","ADY":860,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-283","SUBJID":"id-283","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.78881,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-23 11:49:14","TRTEDTM":"2023-07-24 05:49:14","TRT01SDTM":"2020-07-23 11:49:14","TRT01EDTM":"2022-07-23 23:49:14","TRT02SDTM":"2022-07-23 23:49:14","TRT02EDTM":"2023-07-24 05:49:14","AP01SDTM":"2020-07-23 11:49:14","AP01EDTM":"2022-07-23 23:49:14","AP02SDTM":"2022-07-23 23:49:14","AP02EDTM":"2023-07-24 05:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7455,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.19599,"AVALU":"mg/L","BASE2":7.26991,"BASE":8.3065,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.92607,"PCHG2":26.49374,"CHG":0.88949,"PCHG":10.70838,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-04 11:49:14","ADY":895,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-283","SUBJID":"id-283","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.78881,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-23 11:49:14","TRTEDTM":"2023-07-24 05:49:14","TRT01SDTM":"2020-07-23 11:49:14","TRT01EDTM":"2022-07-23 23:49:14","TRT02SDTM":"2022-07-23 23:49:14","TRT02EDTM":"2023-07-24 05:49:14","AP01SDTM":"2020-07-23 11:49:14","AP01EDTM":"2022-07-23 23:49:14","AP02SDTM":"2022-07-23 23:49:14","AP02EDTM":"2023-07-24 05:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1762,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.47247,"AVALU":"mg/L","BASE2":7.26991,"BASE":8.3065,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.20255,"PCHG2":16.54149,"CHG":0.16597,"PCHG":1.99809,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-17 11:49:14","ADY":1059,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-283","SUBJID":"id-283","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.78881,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-23 11:49:14","TRTEDTM":"2023-07-24 05:49:14","TRT01SDTM":"2020-07-23 11:49:14","TRT01EDTM":"2022-07-23 23:49:14","TRT02SDTM":"2022-07-23 23:49:14","TRT02EDTM":"2023-07-24 05:49:14","AP01SDTM":"2020-07-23 11:49:14","AP01EDTM":"2022-07-23 23:49:14","AP02SDTM":"2022-07-23 23:49:14","AP02EDTM":"2023-07-24 05:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4237,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95083,"AVALU":"g/L","BASE2":2.95083,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-08-07 11:49:14","ADY":15,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-283","SUBJID":"id-283","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.78881,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-23 11:49:14","TRTEDTM":"2023-07-24 05:49:14","TRT01SDTM":"2020-07-23 11:49:14","TRT01EDTM":"2022-07-23 23:49:14","TRT02SDTM":"2022-07-23 23:49:14","TRT02EDTM":"2023-07-24 05:49:14","AP01SDTM":"2020-07-23 11:49:14","AP01EDTM":"2022-07-23 23:49:14","AP02SDTM":"2022-07-23 23:49:14","AP02EDTM":"2023-07-24 05:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4133,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.11824,"AVALU":"g/L","BASE2":2.95083,"BASE":3.11824,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.16741,"PCHG2":5.67331,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2020-12-23 11:49:14","ADY":153,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-283","SUBJID":"id-283","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.78881,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-23 11:49:14","TRTEDTM":"2023-07-24 05:49:14","TRT01SDTM":"2020-07-23 11:49:14","TRT01EDTM":"2022-07-23 23:49:14","TRT02SDTM":"2022-07-23 23:49:14","TRT02EDTM":"2023-07-24 05:49:14","AP01SDTM":"2020-07-23 11:49:14","AP01EDTM":"2022-07-23 23:49:14","AP02SDTM":"2022-07-23 23:49:14","AP02EDTM":"2023-07-24 05:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":984,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86976,"AVALU":"g/L","BASE2":2.95083,"BASE":3.11824,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08107,"PCHG2":-2.7474,"CHG":-0.24848,"PCHG":-7.96862,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-12-14 11:49:14","ADY":509,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-283","SUBJID":"id-283","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.78881,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-23 11:49:14","TRTEDTM":"2023-07-24 05:49:14","TRT01SDTM":"2020-07-23 11:49:14","TRT01EDTM":"2022-07-23 23:49:14","TRT02SDTM":"2022-07-23 23:49:14","TRT02EDTM":"2023-07-24 05:49:14","AP01SDTM":"2020-07-23 11:49:14","AP01EDTM":"2022-07-23 23:49:14","AP02SDTM":"2022-07-23 23:49:14","AP02EDTM":"2023-07-24 05:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7888,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90664,"AVALU":"g/L","BASE2":2.95083,"BASE":3.11824,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04419,"PCHG2":-1.49738,"CHG":-0.21159,"PCHG":-6.78571,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-07-12 11:49:14","ADY":719,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-283","SUBJID":"id-283","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.78881,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-23 11:49:14","TRTEDTM":"2023-07-24 05:49:14","TRT01SDTM":"2020-07-23 11:49:14","TRT01EDTM":"2022-07-23 23:49:14","TRT02SDTM":"2022-07-23 23:49:14","TRT02EDTM":"2023-07-24 05:49:14","AP01SDTM":"2020-07-23 11:49:14","AP01EDTM":"2022-07-23 23:49:14","AP02SDTM":"2022-07-23 23:49:14","AP02EDTM":"2023-07-24 05:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2203,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95651,"AVALU":"g/L","BASE2":2.95083,"BASE":3.11824,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00568,"PCHG2":0.19236,"CHG":-0.16173,"PCHG":-5.18669,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-11-30 11:49:14","ADY":860,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-283","SUBJID":"id-283","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.78881,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-23 11:49:14","TRTEDTM":"2023-07-24 05:49:14","TRT01SDTM":"2020-07-23 11:49:14","TRT01EDTM":"2022-07-23 23:49:14","TRT02SDTM":"2022-07-23 23:49:14","TRT02EDTM":"2023-07-24 05:49:14","AP01SDTM":"2020-07-23 11:49:14","AP01EDTM":"2022-07-23 23:49:14","AP02SDTM":"2022-07-23 23:49:14","AP02EDTM":"2023-07-24 05:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3140,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99073,"AVALU":"g/L","BASE2":2.95083,"BASE":3.11824,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0399,"PCHG2":1.35207,"CHG":-0.12751,"PCHG":-4.08924,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2023-01-04 11:49:14","ADY":895,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-283","SUBJID":"id-283","SITEID":"RUS-11","AGE":37,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.78881,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-23 11:49:14","TRTEDTM":"2023-07-24 05:49:14","TRT01SDTM":"2020-07-23 11:49:14","TRT01EDTM":"2022-07-23 23:49:14","TRT02SDTM":"2022-07-23 23:49:14","TRT02EDTM":"2023-07-24 05:49:14","AP01SDTM":"2020-07-23 11:49:14","AP01EDTM":"2022-07-23 23:49:14","AP02SDTM":"2022-07-23 23:49:14","AP02EDTM":"2023-07-24 05:49:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-12","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4425,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99376,"AVALU":"g/L","BASE2":2.95083,"BASE":3.11824,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04293,"PCHG2":1.4549,"CHG":-0.12448,"PCHG":-3.99193,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2023-06-17 11:49:14","ADY":1059,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-76","SUBJID":"id-76","SITEID":"RUS-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.74484,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-11 14:39:28","TRTEDTM":"2022-08-11 08:39:28","TRT01SDTM":"2019-08-11 14:39:28","TRT01EDTM":"2021-08-11 02:39:28","TRT02SDTM":"2021-08-11 02:39:28","TRT02EDTM":"2022-08-11 08:39:28","AP01SDTM":"2019-08-11 14:39:28","AP01EDTM":"2021-08-11 02:39:28","AP02SDTM":"2021-08-11 02:39:28","AP02EDTM":"2022-08-11 08:39:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-11","EOSDY":1096,"LSTALVDT":"2022-08-21","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5375,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.78087,"AVALU":"U/L","BASE2":29.78087,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-26 14:39:28","ADY":15,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-76","SUBJID":"id-76","SITEID":"RUS-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.74484,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-11 14:39:28","TRTEDTM":"2022-08-11 08:39:28","TRT01SDTM":"2019-08-11 14:39:28","TRT01EDTM":"2021-08-11 02:39:28","TRT02SDTM":"2021-08-11 02:39:28","TRT02EDTM":"2022-08-11 08:39:28","AP01SDTM":"2019-08-11 14:39:28","AP01EDTM":"2021-08-11 02:39:28","AP02SDTM":"2021-08-11 02:39:28","AP02EDTM":"2022-08-11 08:39:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-11","EOSDY":1096,"LSTALVDT":"2022-08-21","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1832,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":39.42323,"AVALU":"U/L","BASE2":29.78087,"BASE":39.42323,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":9.64236,"PCHG2":32.37771,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-18 14:39:28","ADY":160,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-76","SUBJID":"id-76","SITEID":"RUS-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.74484,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-11 14:39:28","TRTEDTM":"2022-08-11 08:39:28","TRT01SDTM":"2019-08-11 14:39:28","TRT01EDTM":"2021-08-11 02:39:28","TRT02SDTM":"2021-08-11 02:39:28","TRT02EDTM":"2022-08-11 08:39:28","AP01SDTM":"2019-08-11 14:39:28","AP01EDTM":"2021-08-11 02:39:28","AP02SDTM":"2021-08-11 02:39:28","AP02EDTM":"2022-08-11 08:39:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-11","EOSDY":1096,"LSTALVDT":"2022-08-21","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":469,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.15827,"AVALU":"U/L","BASE2":29.78087,"BASE":39.42323,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.3774,"PCHG2":11.34084,"CHG":-6.26496,"PCHG":-15.89155,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-26 14:39:28","ADY":228,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-76","SUBJID":"id-76","SITEID":"RUS-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.74484,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-11 14:39:28","TRTEDTM":"2022-08-11 08:39:28","TRT01SDTM":"2019-08-11 14:39:28","TRT01EDTM":"2021-08-11 02:39:28","TRT02SDTM":"2021-08-11 02:39:28","TRT02EDTM":"2022-08-11 08:39:28","AP01SDTM":"2019-08-11 14:39:28","AP01EDTM":"2021-08-11 02:39:28","AP02SDTM":"2021-08-11 02:39:28","AP02EDTM":"2022-08-11 08:39:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-11","EOSDY":1096,"LSTALVDT":"2022-08-21","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":626,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.6504,"AVALU":"U/L","BASE2":29.78087,"BASE":39.42323,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.13047,"PCHG2":-40.73243,"CHG":-21.77284,"PCHG":-55.22844,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-11 14:39:28","ADY":397,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-76","SUBJID":"id-76","SITEID":"RUS-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.74484,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-11 14:39:28","TRTEDTM":"2022-08-11 08:39:28","TRT01SDTM":"2019-08-11 14:39:28","TRT01EDTM":"2021-08-11 02:39:28","TRT02SDTM":"2021-08-11 02:39:28","TRT02EDTM":"2022-08-11 08:39:28","AP01SDTM":"2019-08-11 14:39:28","AP01EDTM":"2021-08-11 02:39:28","AP02SDTM":"2021-08-11 02:39:28","AP02EDTM":"2022-08-11 08:39:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-11","EOSDY":1096,"LSTALVDT":"2022-08-21","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1243,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.65371,"AVALU":"U/L","BASE2":29.78087,"BASE":39.42323,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.12716,"PCHG2":-47.43702,"CHG":-23.76952,"PCHG":-60.29318,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-30 14:39:28","ADY":507,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-76","SUBJID":"id-76","SITEID":"RUS-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.74484,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-11 14:39:28","TRTEDTM":"2022-08-11 08:39:28","TRT01SDTM":"2019-08-11 14:39:28","TRT01EDTM":"2021-08-11 02:39:28","TRT02SDTM":"2021-08-11 02:39:28","TRT02EDTM":"2022-08-11 08:39:28","AP01SDTM":"2019-08-11 14:39:28","AP01EDTM":"2021-08-11 02:39:28","AP02SDTM":"2021-08-11 02:39:28","AP02EDTM":"2022-08-11 08:39:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-11","EOSDY":1096,"LSTALVDT":"2022-08-21","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7120,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.66638,"AVALU":"U/L","BASE2":29.78087,"BASE":39.42323,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.11449,"PCHG2":-40.67877,"CHG":-21.75686,"PCHG":-55.1879,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-20 14:39:28","ADY":771,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-76","SUBJID":"id-76","SITEID":"RUS-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.74484,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-11 14:39:28","TRTEDTM":"2022-08-11 08:39:28","TRT01SDTM":"2019-08-11 14:39:28","TRT01EDTM":"2021-08-11 02:39:28","TRT02SDTM":"2021-08-11 02:39:28","TRT02EDTM":"2022-08-11 08:39:28","AP01SDTM":"2019-08-11 14:39:28","AP01EDTM":"2021-08-11 02:39:28","AP02SDTM":"2021-08-11 02:39:28","AP02EDTM":"2022-08-11 08:39:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-11","EOSDY":1096,"LSTALVDT":"2022-08-21","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4501,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.82709,"AVALU":"U/L","BASE2":29.78087,"BASE":39.42323,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.95378,"PCHG2":-30.06553,"CHG":-18.59614,"PCHG":-47.17051,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-29 14:39:28","ADY":871,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-76","SUBJID":"id-76","SITEID":"RUS-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.74484,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-11 14:39:28","TRTEDTM":"2022-08-11 08:39:28","TRT01SDTM":"2019-08-11 14:39:28","TRT01EDTM":"2021-08-11 02:39:28","TRT02SDTM":"2021-08-11 02:39:28","TRT02EDTM":"2022-08-11 08:39:28","AP01SDTM":"2019-08-11 14:39:28","AP01EDTM":"2021-08-11 02:39:28","AP02SDTM":"2021-08-11 02:39:28","AP02EDTM":"2022-08-11 08:39:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-11","EOSDY":1096,"LSTALVDT":"2022-08-21","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2493,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.92319,"AVALU":"mg/L","BASE2":8.92319,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-26 14:39:28","ADY":15,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-76","SUBJID":"id-76","SITEID":"RUS-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.74484,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-11 14:39:28","TRTEDTM":"2022-08-11 08:39:28","TRT01SDTM":"2019-08-11 14:39:28","TRT01EDTM":"2021-08-11 02:39:28","TRT02SDTM":"2021-08-11 02:39:28","TRT02EDTM":"2022-08-11 08:39:28","AP01SDTM":"2019-08-11 14:39:28","AP01EDTM":"2021-08-11 02:39:28","AP02SDTM":"2021-08-11 02:39:28","AP02EDTM":"2022-08-11 08:39:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-11","EOSDY":1096,"LSTALVDT":"2022-08-21","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4347,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.17572,"AVALU":"mg/L","BASE2":8.92319,"BASE":9.17572,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.25253,"PCHG2":2.83002,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-18 14:39:28","ADY":160,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-76","SUBJID":"id-76","SITEID":"RUS-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.74484,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-11 14:39:28","TRTEDTM":"2022-08-11 08:39:28","TRT01SDTM":"2019-08-11 14:39:28","TRT01EDTM":"2021-08-11 02:39:28","TRT02SDTM":"2021-08-11 02:39:28","TRT02EDTM":"2022-08-11 08:39:28","AP01SDTM":"2019-08-11 14:39:28","AP01EDTM":"2021-08-11 02:39:28","AP02SDTM":"2021-08-11 02:39:28","AP02EDTM":"2022-08-11 08:39:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-11","EOSDY":1096,"LSTALVDT":"2022-08-21","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":774,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.17086,"AVALU":"mg/L","BASE2":8.92319,"BASE":9.17572,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.24767,"PCHG2":25.1891,"CHG":1.99514,"PCHG":21.74372,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-03-26 14:39:28","ADY":228,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-76","SUBJID":"id-76","SITEID":"RUS-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.74484,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-11 14:39:28","TRTEDTM":"2022-08-11 08:39:28","TRT01SDTM":"2019-08-11 14:39:28","TRT01EDTM":"2021-08-11 02:39:28","TRT02SDTM":"2021-08-11 02:39:28","TRT02EDTM":"2022-08-11 08:39:28","AP01SDTM":"2019-08-11 14:39:28","AP01EDTM":"2021-08-11 02:39:28","AP02SDTM":"2021-08-11 02:39:28","AP02EDTM":"2022-08-11 08:39:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-11","EOSDY":1096,"LSTALVDT":"2022-08-21","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6680,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.76382,"AVALU":"mg/L","BASE2":8.92319,"BASE":9.17572,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15937,"PCHG2":-1.78597,"CHG":-0.41189,"PCHG":-4.48895,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-11 14:39:28","ADY":397,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-76","SUBJID":"id-76","SITEID":"RUS-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.74484,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-11 14:39:28","TRTEDTM":"2022-08-11 08:39:28","TRT01SDTM":"2019-08-11 14:39:28","TRT01EDTM":"2021-08-11 02:39:28","TRT02SDTM":"2021-08-11 02:39:28","TRT02EDTM":"2022-08-11 08:39:28","AP01SDTM":"2019-08-11 14:39:28","AP01EDTM":"2021-08-11 02:39:28","AP02SDTM":"2021-08-11 02:39:28","AP02EDTM":"2022-08-11 08:39:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-11","EOSDY":1096,"LSTALVDT":"2022-08-21","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7724,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.98768,"AVALU":"mg/L","BASE2":8.92319,"BASE":9.17572,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.06449,"PCHG2":23.13628,"CHG":1.81197,"PCHG":19.7474,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-12-30 14:39:28","ADY":507,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-76","SUBJID":"id-76","SITEID":"RUS-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.74484,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-11 14:39:28","TRTEDTM":"2022-08-11 08:39:28","TRT01SDTM":"2019-08-11 14:39:28","TRT01EDTM":"2021-08-11 02:39:28","TRT02SDTM":"2021-08-11 02:39:28","TRT02EDTM":"2022-08-11 08:39:28","AP01SDTM":"2019-08-11 14:39:28","AP01EDTM":"2021-08-11 02:39:28","AP02SDTM":"2021-08-11 02:39:28","AP02EDTM":"2022-08-11 08:39:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-11","EOSDY":1096,"LSTALVDT":"2022-08-21","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2382,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.28917,"AVALU":"mg/L","BASE2":8.92319,"BASE":9.17572,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.36598,"PCHG2":4.1015,"CHG":0.11346,"PCHG":1.23648,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-20 14:39:28","ADY":771,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-76","SUBJID":"id-76","SITEID":"RUS-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.74484,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-11 14:39:28","TRTEDTM":"2022-08-11 08:39:28","TRT01SDTM":"2019-08-11 14:39:28","TRT01EDTM":"2021-08-11 02:39:28","TRT02SDTM":"2021-08-11 02:39:28","TRT02EDTM":"2022-08-11 08:39:28","AP01SDTM":"2019-08-11 14:39:28","AP01EDTM":"2021-08-11 02:39:28","AP02SDTM":"2021-08-11 02:39:28","AP02EDTM":"2022-08-11 08:39:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-11","EOSDY":1096,"LSTALVDT":"2022-08-21","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8160,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.32682,"AVALU":"mg/L","BASE2":8.92319,"BASE":9.17572,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.40363,"PCHG2":4.52339,"CHG":0.1511,"PCHG":1.64676,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-29 14:39:28","ADY":871,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-76","SUBJID":"id-76","SITEID":"RUS-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.74484,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-11 14:39:28","TRTEDTM":"2022-08-11 08:39:28","TRT01SDTM":"2019-08-11 14:39:28","TRT01EDTM":"2021-08-11 02:39:28","TRT02SDTM":"2021-08-11 02:39:28","TRT02EDTM":"2022-08-11 08:39:28","AP01SDTM":"2019-08-11 14:39:28","AP01EDTM":"2021-08-11 02:39:28","AP02SDTM":"2021-08-11 02:39:28","AP02EDTM":"2022-08-11 08:39:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-11","EOSDY":1096,"LSTALVDT":"2022-08-21","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5427,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97897,"AVALU":"g/L","BASE2":2.97897,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-26 14:39:28","ADY":15,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-76","SUBJID":"id-76","SITEID":"RUS-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.74484,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-11 14:39:28","TRTEDTM":"2022-08-11 08:39:28","TRT01SDTM":"2019-08-11 14:39:28","TRT01EDTM":"2021-08-11 02:39:28","TRT02SDTM":"2021-08-11 02:39:28","TRT02EDTM":"2022-08-11 08:39:28","AP01SDTM":"2019-08-11 14:39:28","AP01EDTM":"2021-08-11 02:39:28","AP02SDTM":"2021-08-11 02:39:28","AP02EDTM":"2022-08-11 08:39:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-11","EOSDY":1096,"LSTALVDT":"2022-08-21","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3668,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80627,"AVALU":"g/L","BASE2":2.97897,"BASE":2.80627,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.17269,"PCHG2":-5.79708,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-18 14:39:28","ADY":160,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-76","SUBJID":"id-76","SITEID":"RUS-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.74484,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-11 14:39:28","TRTEDTM":"2022-08-11 08:39:28","TRT01SDTM":"2019-08-11 14:39:28","TRT01EDTM":"2021-08-11 02:39:28","TRT02SDTM":"2021-08-11 02:39:28","TRT02EDTM":"2022-08-11 08:39:28","AP01SDTM":"2019-08-11 14:39:28","AP01EDTM":"2021-08-11 02:39:28","AP02SDTM":"2021-08-11 02:39:28","AP02EDTM":"2022-08-11 08:39:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-11","EOSDY":1096,"LSTALVDT":"2022-08-21","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4100,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84443,"AVALU":"g/L","BASE2":2.97897,"BASE":2.80627,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13453,"PCHG2":-4.5161,"CHG":0.03816,"PCHG":1.35981,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-26 14:39:28","ADY":228,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-76","SUBJID":"id-76","SITEID":"RUS-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.74484,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-11 14:39:28","TRTEDTM":"2022-08-11 08:39:28","TRT01SDTM":"2019-08-11 14:39:28","TRT01EDTM":"2021-08-11 02:39:28","TRT02SDTM":"2021-08-11 02:39:28","TRT02EDTM":"2022-08-11 08:39:28","AP01SDTM":"2019-08-11 14:39:28","AP01EDTM":"2021-08-11 02:39:28","AP02SDTM":"2021-08-11 02:39:28","AP02EDTM":"2022-08-11 08:39:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-11","EOSDY":1096,"LSTALVDT":"2022-08-21","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5092,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92358,"AVALU":"g/L","BASE2":2.97897,"BASE":2.80627,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05539,"PCHG2":-1.85921,"CHG":0.11731,"PCHG":4.1802,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-11 14:39:28","ADY":397,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-76","SUBJID":"id-76","SITEID":"RUS-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.74484,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-11 14:39:28","TRTEDTM":"2022-08-11 08:39:28","TRT01SDTM":"2019-08-11 14:39:28","TRT01EDTM":"2021-08-11 02:39:28","TRT02SDTM":"2021-08-11 02:39:28","TRT02EDTM":"2022-08-11 08:39:28","AP01SDTM":"2019-08-11 14:39:28","AP01EDTM":"2021-08-11 02:39:28","AP02SDTM":"2021-08-11 02:39:28","AP02EDTM":"2022-08-11 08:39:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-11","EOSDY":1096,"LSTALVDT":"2022-08-21","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1896,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98251,"AVALU":"g/L","BASE2":2.97897,"BASE":2.80627,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00354,"PCHG2":0.11883,"CHG":0.17623,"PCHG":6.27996,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-30 14:39:28","ADY":507,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-76","SUBJID":"id-76","SITEID":"RUS-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.74484,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-11 14:39:28","TRTEDTM":"2022-08-11 08:39:28","TRT01SDTM":"2019-08-11 14:39:28","TRT01EDTM":"2021-08-11 02:39:28","TRT02SDTM":"2021-08-11 02:39:28","TRT02EDTM":"2022-08-11 08:39:28","AP01SDTM":"2019-08-11 14:39:28","AP01EDTM":"2021-08-11 02:39:28","AP02SDTM":"2021-08-11 02:39:28","AP02EDTM":"2022-08-11 08:39:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-11","EOSDY":1096,"LSTALVDT":"2022-08-21","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8176,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.64977,"AVALU":"g/L","BASE2":2.97897,"BASE":2.80627,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.32919,"PCHG2":-11.05057,"CHG":-0.1565,"PCHG":-5.57678,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-20 14:39:28","ADY":771,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-76","SUBJID":"id-76","SITEID":"RUS-11","AGE":25,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.74484,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-11 14:39:28","TRTEDTM":"2022-08-11 08:39:28","TRT01SDTM":"2019-08-11 14:39:28","TRT01EDTM":"2021-08-11 02:39:28","TRT02SDTM":"2021-08-11 02:39:28","TRT02EDTM":"2022-08-11 08:39:28","AP01SDTM":"2019-08-11 14:39:28","AP01EDTM":"2021-08-11 02:39:28","AP02SDTM":"2021-08-11 02:39:28","AP02EDTM":"2022-08-11 08:39:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-11","EOSDY":1096,"LSTALVDT":"2022-08-21","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4566,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89563,"AVALU":"g/L","BASE2":2.97897,"BASE":2.80627,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08334,"PCHG2":-2.79759,"CHG":0.08935,"PCHG":3.18407,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-29 14:39:28","ADY":871,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-94","SUBJID":"id-94","SITEID":"RUS-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.31688,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-19","TRTSDTM":"2019-08-23 21:17:59","TRTEDTM":"2022-02-12 07:49:07","TRT01SDTM":"2019-08-23 21:17:59","TRT01EDTM":"2021-02-12 01:49:07","TRT02SDTM":"2021-02-12 01:49:07","TRT02EDTM":"2022-02-12 07:49:07","AP01SDTM":"2019-08-23 21:17:59","AP01EDTM":"2021-02-12 01:49:07","AP02SDTM":"2021-02-12 01:49:07","AP02EDTM":"2022-02-12 07:49:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":953,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1576,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.95816,"AVALU":"U/L","BASE2":14.95816,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-03 21:17:59","ADY":133,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-94","SUBJID":"id-94","SITEID":"RUS-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.31688,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-19","TRTSDTM":"2019-08-23 21:17:59","TRTEDTM":"2022-02-12 07:49:07","TRT01SDTM":"2019-08-23 21:17:59","TRT01EDTM":"2021-02-12 01:49:07","TRT02SDTM":"2021-02-12 01:49:07","TRT02EDTM":"2022-02-12 07:49:07","AP01SDTM":"2019-08-23 21:17:59","AP01EDTM":"2021-02-12 01:49:07","AP02SDTM":"2021-02-12 01:49:07","AP02EDTM":"2022-02-12 07:49:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":953,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":786,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.45928,"AVALU":"U/L","BASE2":14.95816,"BASE":29.45928,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":14.50112,"PCHG2":96.94455,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-09 21:17:59","ADY":139,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-94","SUBJID":"id-94","SITEID":"RUS-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.31688,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-19","TRTSDTM":"2019-08-23 21:17:59","TRTEDTM":"2022-02-12 07:49:07","TRT01SDTM":"2019-08-23 21:17:59","TRT01EDTM":"2021-02-12 01:49:07","TRT02SDTM":"2021-02-12 01:49:07","TRT02EDTM":"2022-02-12 07:49:07","AP01SDTM":"2019-08-23 21:17:59","AP01EDTM":"2021-02-12 01:49:07","AP02SDTM":"2021-02-12 01:49:07","AP02EDTM":"2022-02-12 07:49:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":953,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5133,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.27156,"AVALU":"U/L","BASE2":14.95816,"BASE":29.45928,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.3134,"PCHG2":55.57769,"CHG":-6.18772,"PCHG":-21.00431,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-26 21:17:59","ADY":187,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-94","SUBJID":"id-94","SITEID":"RUS-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.31688,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-19","TRTSDTM":"2019-08-23 21:17:59","TRTEDTM":"2022-02-12 07:49:07","TRT01SDTM":"2019-08-23 21:17:59","TRT01EDTM":"2021-02-12 01:49:07","TRT02SDTM":"2021-02-12 01:49:07","TRT02EDTM":"2022-02-12 07:49:07","AP01SDTM":"2019-08-23 21:17:59","AP01EDTM":"2021-02-12 01:49:07","AP02SDTM":"2021-02-12 01:49:07","AP02EDTM":"2022-02-12 07:49:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":953,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4807,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.63462,"AVALU":"U/L","BASE2":14.95816,"BASE":29.45928,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.67645,"PCHG2":31.26357,"CHG":-9.82467,"PCHG":-33.34999,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-22 21:17:59","ADY":273,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-94","SUBJID":"id-94","SITEID":"RUS-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.31688,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-19","TRTSDTM":"2019-08-23 21:17:59","TRTEDTM":"2022-02-12 07:49:07","TRT01SDTM":"2019-08-23 21:17:59","TRT01EDTM":"2021-02-12 01:49:07","TRT02SDTM":"2021-02-12 01:49:07","TRT02EDTM":"2022-02-12 07:49:07","AP01SDTM":"2019-08-23 21:17:59","AP01EDTM":"2021-02-12 01:49:07","AP02SDTM":"2021-02-12 01:49:07","AP02EDTM":"2022-02-12 07:49:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":953,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1755,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.79595,"AVALU":"U/L","BASE2":14.95816,"BASE":29.45928,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.16222,"PCHG2":-27.82571,"CHG":-18.66334,"PCHG":-63.35299,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-15 21:17:59","ADY":601,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-94","SUBJID":"id-94","SITEID":"RUS-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.31688,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-19","TRTSDTM":"2019-08-23 21:17:59","TRTEDTM":"2022-02-12 07:49:07","TRT01SDTM":"2019-08-23 21:17:59","TRT01EDTM":"2021-02-12 01:49:07","TRT02SDTM":"2021-02-12 01:49:07","TRT02EDTM":"2022-02-12 07:49:07","AP01SDTM":"2019-08-23 21:17:59","AP01EDTM":"2021-02-12 01:49:07","AP02SDTM":"2021-02-12 01:49:07","AP02EDTM":"2022-02-12 07:49:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":953,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2054,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.07053,"AVALU":"U/L","BASE2":14.95816,"BASE":29.45928,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.88763,"PCHG2":-86.15784,"CHG":-27.38875,"PCHG":-92.97154,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-05-22 21:17:59","ADY":638,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-94","SUBJID":"id-94","SITEID":"RUS-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.31688,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-19","TRTSDTM":"2019-08-23 21:17:59","TRTEDTM":"2022-02-12 07:49:07","TRT01SDTM":"2019-08-23 21:17:59","TRT01EDTM":"2021-02-12 01:49:07","TRT02SDTM":"2021-02-12 01:49:07","TRT02EDTM":"2022-02-12 07:49:07","AP01SDTM":"2019-08-23 21:17:59","AP01EDTM":"2021-02-12 01:49:07","AP02SDTM":"2021-02-12 01:49:07","AP02EDTM":"2022-02-12 07:49:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":953,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8198,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.82141,"AVALU":"U/L","BASE2":14.95816,"BASE":29.45928,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.13675,"PCHG2":-41.02612,"CHG":-20.63787,"PCHG":-70.05559,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-04 21:17:59","ADY":834,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-94","SUBJID":"id-94","SITEID":"RUS-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.31688,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-19","TRTSDTM":"2019-08-23 21:17:59","TRTEDTM":"2022-02-12 07:49:07","TRT01SDTM":"2019-08-23 21:17:59","TRT01EDTM":"2021-02-12 01:49:07","TRT02SDTM":"2021-02-12 01:49:07","TRT02EDTM":"2022-02-12 07:49:07","AP01SDTM":"2019-08-23 21:17:59","AP01EDTM":"2021-02-12 01:49:07","AP02SDTM":"2021-02-12 01:49:07","AP02EDTM":"2022-02-12 07:49:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":953,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6384,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.41746,"AVALU":"mg/L","BASE2":9.41746,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-03 21:17:59","ADY":133,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-94","SUBJID":"id-94","SITEID":"RUS-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.31688,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-19","TRTSDTM":"2019-08-23 21:17:59","TRTEDTM":"2022-02-12 07:49:07","TRT01SDTM":"2019-08-23 21:17:59","TRT01EDTM":"2021-02-12 01:49:07","TRT02SDTM":"2021-02-12 01:49:07","TRT02EDTM":"2022-02-12 07:49:07","AP01SDTM":"2019-08-23 21:17:59","AP01EDTM":"2021-02-12 01:49:07","AP02SDTM":"2021-02-12 01:49:07","AP02EDTM":"2022-02-12 07:49:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":953,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3915,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.25426,"AVALU":"mg/L","BASE2":9.41746,"BASE":8.25426,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.1632,"PCHG2":-12.35155,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-09 21:17:59","ADY":139,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-94","SUBJID":"id-94","SITEID":"RUS-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.31688,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-19","TRTSDTM":"2019-08-23 21:17:59","TRTEDTM":"2022-02-12 07:49:07","TRT01SDTM":"2019-08-23 21:17:59","TRT01EDTM":"2021-02-12 01:49:07","TRT02SDTM":"2021-02-12 01:49:07","TRT02EDTM":"2022-02-12 07:49:07","AP01SDTM":"2019-08-23 21:17:59","AP01EDTM":"2021-02-12 01:49:07","AP02SDTM":"2021-02-12 01:49:07","AP02EDTM":"2022-02-12 07:49:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":953,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3445,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.52373,"AVALU":"mg/L","BASE2":9.41746,"BASE":8.25426,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10627,"PCHG2":1.12839,"CHG":1.26947,"PCHG":15.37956,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-26 21:17:59","ADY":187,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-94","SUBJID":"id-94","SITEID":"RUS-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.31688,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-19","TRTSDTM":"2019-08-23 21:17:59","TRTEDTM":"2022-02-12 07:49:07","TRT01SDTM":"2019-08-23 21:17:59","TRT01EDTM":"2021-02-12 01:49:07","TRT02SDTM":"2021-02-12 01:49:07","TRT02EDTM":"2022-02-12 07:49:07","AP01SDTM":"2019-08-23 21:17:59","AP01EDTM":"2021-02-12 01:49:07","AP02SDTM":"2021-02-12 01:49:07","AP02EDTM":"2022-02-12 07:49:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":953,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":736,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.36062,"AVALU":"mg/L","BASE2":9.41746,"BASE":8.25426,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.94316,"PCHG2":10.01498,"CHG":2.10636,"PCHG":25.51846,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-05-22 21:17:59","ADY":273,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-94","SUBJID":"id-94","SITEID":"RUS-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.31688,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-19","TRTSDTM":"2019-08-23 21:17:59","TRTEDTM":"2022-02-12 07:49:07","TRT01SDTM":"2019-08-23 21:17:59","TRT01EDTM":"2021-02-12 01:49:07","TRT02SDTM":"2021-02-12 01:49:07","TRT02EDTM":"2022-02-12 07:49:07","AP01SDTM":"2019-08-23 21:17:59","AP01EDTM":"2021-02-12 01:49:07","AP02SDTM":"2021-02-12 01:49:07","AP02EDTM":"2022-02-12 07:49:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":953,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5131,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.8494,"AVALU":"mg/L","BASE2":9.41746,"BASE":8.25426,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.56806,"PCHG2":-6.03198,"CHG":0.59514,"PCHG":7.21013,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-15 21:17:59","ADY":601,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-94","SUBJID":"id-94","SITEID":"RUS-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.31688,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-19","TRTSDTM":"2019-08-23 21:17:59","TRTEDTM":"2022-02-12 07:49:07","TRT01SDTM":"2019-08-23 21:17:59","TRT01EDTM":"2021-02-12 01:49:07","TRT02SDTM":"2021-02-12 01:49:07","TRT02EDTM":"2022-02-12 07:49:07","AP01SDTM":"2019-08-23 21:17:59","AP01EDTM":"2021-02-12 01:49:07","AP02SDTM":"2021-02-12 01:49:07","AP02EDTM":"2022-02-12 07:49:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":953,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1539,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.71838,"AVALU":"mg/L","BASE2":9.41746,"BASE":8.25426,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.69908,"PCHG2":-7.42327,"CHG":0.46412,"PCHG":5.62278,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-22 21:17:59","ADY":638,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-94","SUBJID":"id-94","SITEID":"RUS-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.31688,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-19","TRTSDTM":"2019-08-23 21:17:59","TRTEDTM":"2022-02-12 07:49:07","TRT01SDTM":"2019-08-23 21:17:59","TRT01EDTM":"2021-02-12 01:49:07","TRT02SDTM":"2021-02-12 01:49:07","TRT02EDTM":"2022-02-12 07:49:07","AP01SDTM":"2019-08-23 21:17:59","AP01EDTM":"2021-02-12 01:49:07","AP02SDTM":"2021-02-12 01:49:07","AP02EDTM":"2022-02-12 07:49:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":953,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2898,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.86913,"AVALU":"mg/L","BASE2":9.41746,"BASE":8.25426,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.54833,"PCHG2":-5.82248,"CHG":0.61487,"PCHG":7.44915,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-04 21:17:59","ADY":834,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-94","SUBJID":"id-94","SITEID":"RUS-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.31688,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-19","TRTSDTM":"2019-08-23 21:17:59","TRTEDTM":"2022-02-12 07:49:07","TRT01SDTM":"2019-08-23 21:17:59","TRT01EDTM":"2021-02-12 01:49:07","TRT02SDTM":"2021-02-12 01:49:07","TRT02EDTM":"2022-02-12 07:49:07","AP01SDTM":"2019-08-23 21:17:59","AP01EDTM":"2021-02-12 01:49:07","AP02SDTM":"2021-02-12 01:49:07","AP02EDTM":"2022-02-12 07:49:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":953,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3470,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91269,"AVALU":"g/L","BASE2":2.91269,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-03 21:17:59","ADY":133,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-94","SUBJID":"id-94","SITEID":"RUS-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.31688,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-19","TRTSDTM":"2019-08-23 21:17:59","TRTEDTM":"2022-02-12 07:49:07","TRT01SDTM":"2019-08-23 21:17:59","TRT01EDTM":"2021-02-12 01:49:07","TRT02SDTM":"2021-02-12 01:49:07","TRT02EDTM":"2022-02-12 07:49:07","AP01SDTM":"2019-08-23 21:17:59","AP01EDTM":"2021-02-12 01:49:07","AP02SDTM":"2021-02-12 01:49:07","AP02EDTM":"2022-02-12 07:49:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":953,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5241,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91221,"AVALU":"g/L","BASE2":2.91269,"BASE":2.91221,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.00049,"PCHG2":-0.01671,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-09 21:17:59","ADY":139,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-94","SUBJID":"id-94","SITEID":"RUS-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.31688,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-19","TRTSDTM":"2019-08-23 21:17:59","TRTEDTM":"2022-02-12 07:49:07","TRT01SDTM":"2019-08-23 21:17:59","TRT01EDTM":"2021-02-12 01:49:07","TRT02SDTM":"2021-02-12 01:49:07","TRT02EDTM":"2022-02-12 07:49:07","AP01SDTM":"2019-08-23 21:17:59","AP01EDTM":"2021-02-12 01:49:07","AP02SDTM":"2021-02-12 01:49:07","AP02EDTM":"2022-02-12 07:49:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":953,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":237,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89706,"AVALU":"g/L","BASE2":2.91269,"BASE":2.91221,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01564,"PCHG2":-0.53684,"CHG":-0.01515,"PCHG":-0.52022,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-26 21:17:59","ADY":187,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-94","SUBJID":"id-94","SITEID":"RUS-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.31688,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-19","TRTSDTM":"2019-08-23 21:17:59","TRTEDTM":"2022-02-12 07:49:07","TRT01SDTM":"2019-08-23 21:17:59","TRT01EDTM":"2021-02-12 01:49:07","TRT02SDTM":"2021-02-12 01:49:07","TRT02EDTM":"2022-02-12 07:49:07","AP01SDTM":"2019-08-23 21:17:59","AP01EDTM":"2021-02-12 01:49:07","AP02SDTM":"2021-02-12 01:49:07","AP02EDTM":"2022-02-12 07:49:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":953,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1287,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85633,"AVALU":"g/L","BASE2":2.91269,"BASE":2.91221,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05637,"PCHG2":-1.93519,"CHG":-0.05588,"PCHG":-1.9188,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-22 21:17:59","ADY":273,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-94","SUBJID":"id-94","SITEID":"RUS-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.31688,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-19","TRTSDTM":"2019-08-23 21:17:59","TRTEDTM":"2022-02-12 07:49:07","TRT01SDTM":"2019-08-23 21:17:59","TRT01EDTM":"2021-02-12 01:49:07","TRT02SDTM":"2021-02-12 01:49:07","TRT02EDTM":"2022-02-12 07:49:07","AP01SDTM":"2019-08-23 21:17:59","AP01EDTM":"2021-02-12 01:49:07","AP02SDTM":"2021-02-12 01:49:07","AP02EDTM":"2022-02-12 07:49:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":953,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2857,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87321,"AVALU":"g/L","BASE2":2.91269,"BASE":2.91221,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03949,"PCHG2":-1.35565,"CHG":-0.039,"PCHG":-1.33917,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-15 21:17:59","ADY":601,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-94","SUBJID":"id-94","SITEID":"RUS-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.31688,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-19","TRTSDTM":"2019-08-23 21:17:59","TRTEDTM":"2022-02-12 07:49:07","TRT01SDTM":"2019-08-23 21:17:59","TRT01EDTM":"2021-02-12 01:49:07","TRT02SDTM":"2021-02-12 01:49:07","TRT02EDTM":"2022-02-12 07:49:07","AP01SDTM":"2019-08-23 21:17:59","AP01EDTM":"2021-02-12 01:49:07","AP02SDTM":"2021-02-12 01:49:07","AP02EDTM":"2022-02-12 07:49:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":953,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3928,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92373,"AVALU":"g/L","BASE2":2.91269,"BASE":2.91221,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01104,"PCHG2":0.37889,"CHG":0.01152,"PCHG":0.39567,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-22 21:17:59","ADY":638,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-11-id-94","SUBJID":"id-94","SITEID":"RUS-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-11","INVNAM":"Dr. RUS-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":9.31688,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-19","TRTSDTM":"2019-08-23 21:17:59","TRTEDTM":"2022-02-12 07:49:07","TRT01SDTM":"2019-08-23 21:17:59","TRT01EDTM":"2021-02-12 01:49:07","TRT02SDTM":"2021-02-12 01:49:07","TRT02EDTM":"2022-02-12 07:49:07","AP01SDTM":"2019-08-23 21:17:59","AP01EDTM":"2021-02-12 01:49:07","AP02SDTM":"2021-02-12 01:49:07","AP02EDTM":"2022-02-12 07:49:07","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":904,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":953,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5946,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75708,"AVALU":"g/L","BASE2":2.91269,"BASE":2.91221,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15561,"PCHG2":-5.34259,"CHG":-0.15513,"PCHG":-5.32677,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-04 21:17:59","ADY":834,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-12-id-185","SUBJID":"id-185","SITEID":"RUS-12","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-12","INVNAM":"Dr. RUS-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":7.67625,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-08 11:19:06","TRT01SDTM":"2019-12-08 11:19:06","AP01SDTM":"2019-12-08 11:19:06","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5970,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.8144,"AVALU":"U/L","BASE2":17.8144,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-12 11:19:06","ADY":35,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-12-id-185","SUBJID":"id-185","SITEID":"RUS-12","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-12","INVNAM":"Dr. RUS-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":7.67625,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-08 11:19:06","TRT01SDTM":"2019-12-08 11:19:06","AP01SDTM":"2019-12-08 11:19:06","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2451,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.91351,"AVALU":"U/L","BASE2":17.8144,"BASE":25.91351,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":8.0991,"PCHG2":45.46381,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-28 11:19:06","ADY":142,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-12-id-185","SUBJID":"id-185","SITEID":"RUS-12","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-12","INVNAM":"Dr. RUS-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":7.67625,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-08 11:19:06","TRT01SDTM":"2019-12-08 11:19:06","AP01SDTM":"2019-12-08 11:19:06","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3160,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.66892,"AVALU":"U/L","BASE2":17.8144,"BASE":25.91351,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.14548,"PCHG2":-12.04352,"CHG":-10.24459,"PCHG":-39.53377,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-18 11:19:06","ADY":162,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-12-id-185","SUBJID":"id-185","SITEID":"RUS-12","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-12","INVNAM":"Dr. RUS-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":7.67625,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-08 11:19:06","TRT01SDTM":"2019-12-08 11:19:06","AP01SDTM":"2019-12-08 11:19:06","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2718,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.85534,"AVALU":"U/L","BASE2":17.8144,"BASE":25.91351,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.95906,"PCHG2":-72.74487,"CHG":-21.05817,"PCHG":-81.26329,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-07-29 11:19:06","ADY":234,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-12-id-185","SUBJID":"id-185","SITEID":"RUS-12","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-12","INVNAM":"Dr. RUS-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":7.67625,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-08 11:19:06","TRT01SDTM":"2019-12-08 11:19:06","AP01SDTM":"2019-12-08 11:19:06","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4884,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.5441,"AVALU":"U/L","BASE2":17.8144,"BASE":25.91351,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.7297,"PCHG2":15.323,"CHG":-5.3694,"PCHG":-20.72048,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-26 11:19:06","ADY":293,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-12-id-185","SUBJID":"id-185","SITEID":"RUS-12","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-12","INVNAM":"Dr. RUS-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":7.67625,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-08 11:19:06","TRT01SDTM":"2019-12-08 11:19:06","AP01SDTM":"2019-12-08 11:19:06","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1692,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.78135,"AVALU":"U/L","BASE2":17.8144,"BASE":25.91351,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.03305,"PCHG2":-22.63927,"CHG":-12.13216,"PCHG":-46.81789,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-30 11:19:06","ADY":509,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-12-id-185","SUBJID":"id-185","SITEID":"RUS-12","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-12","INVNAM":"Dr. RUS-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":7.67625,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-08 11:19:06","TRT01SDTM":"2019-12-08 11:19:06","AP01SDTM":"2019-12-08 11:19:06","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4253,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":35.65309,"AVALU":"U/L","BASE2":17.8144,"BASE":25.91351,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":17.83869,"PCHG2":100.13632,"CHG":9.73958,"PCHG":37.58496,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-18 11:19:06","ADY":650,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-12-id-185","SUBJID":"id-185","SITEID":"RUS-12","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-12","INVNAM":"Dr. RUS-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":7.67625,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-08 11:19:06","TRT01SDTM":"2019-12-08 11:19:06","AP01SDTM":"2019-12-08 11:19:06","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1344,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.29618,"AVALU":"mg/L","BASE2":8.29618,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-12 11:19:06","ADY":35,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-12-id-185","SUBJID":"id-185","SITEID":"RUS-12","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-12","INVNAM":"Dr. RUS-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":7.67625,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-08 11:19:06","TRT01SDTM":"2019-12-08 11:19:06","AP01SDTM":"2019-12-08 11:19:06","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4661,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.49021,"AVALU":"mg/L","BASE2":8.29618,"BASE":8.49021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.19402,"PCHG2":2.33872,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-28 11:19:06","ADY":142,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-12-id-185","SUBJID":"id-185","SITEID":"RUS-12","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-12","INVNAM":"Dr. RUS-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":7.67625,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-08 11:19:06","TRT01SDTM":"2019-12-08 11:19:06","AP01SDTM":"2019-12-08 11:19:06","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5275,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.8487,"AVALU":"mg/L","BASE2":8.29618,"BASE":8.49021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.44749,"PCHG2":-5.39387,"CHG":-0.64151,"PCHG":-7.55588,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-05-18 11:19:06","ADY":162,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-12-id-185","SUBJID":"id-185","SITEID":"RUS-12","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-12","INVNAM":"Dr. RUS-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":7.67625,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-08 11:19:06","TRT01SDTM":"2019-12-08 11:19:06","AP01SDTM":"2019-12-08 11:19:06","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":374,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.25145,"AVALU":"mg/L","BASE2":8.29618,"BASE":8.49021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.95526,"PCHG2":11.5145,"CHG":0.76124,"PCHG":8.96609,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-29 11:19:06","ADY":234,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-12-id-185","SUBJID":"id-185","SITEID":"RUS-12","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-12","INVNAM":"Dr. RUS-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":7.67625,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-08 11:19:06","TRT01SDTM":"2019-12-08 11:19:06","AP01SDTM":"2019-12-08 11:19:06","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1107,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.28837,"AVALU":"mg/L","BASE2":8.29618,"BASE":8.49021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00782,"PCHG2":-0.09424,"CHG":-0.20184,"PCHG":-2.37736,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-26 11:19:06","ADY":293,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-12-id-185","SUBJID":"id-185","SITEID":"RUS-12","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-12","INVNAM":"Dr. RUS-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":7.67625,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-08 11:19:06","TRT01SDTM":"2019-12-08 11:19:06","AP01SDTM":"2019-12-08 11:19:06","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4533,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.3157,"AVALU":"mg/L","BASE2":8.29618,"BASE":8.49021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01952,"PCHG2":0.23529,"CHG":-0.1745,"PCHG":-2.05536,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-30 11:19:06","ADY":509,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-12-id-185","SUBJID":"id-185","SITEID":"RUS-12","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-12","INVNAM":"Dr. RUS-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":7.67625,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-08 11:19:06","TRT01SDTM":"2019-12-08 11:19:06","AP01SDTM":"2019-12-08 11:19:06","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5285,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.69492,"AVALU":"mg/L","BASE2":8.29618,"BASE":8.49021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.39874,"PCHG2":28.91379,"CHG":2.20472,"PCHG":25.96776,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-09-18 11:19:06","ADY":650,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-12-id-185","SUBJID":"id-185","SITEID":"RUS-12","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-12","INVNAM":"Dr. RUS-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":7.67625,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-08 11:19:06","TRT01SDTM":"2019-12-08 11:19:06","AP01SDTM":"2019-12-08 11:19:06","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1109,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8034,"AVALU":"g/L","BASE2":2.8034,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-01-12 11:19:06","ADY":35,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-12-id-185","SUBJID":"id-185","SITEID":"RUS-12","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-12","INVNAM":"Dr. RUS-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":7.67625,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-08 11:19:06","TRT01SDTM":"2019-12-08 11:19:06","AP01SDTM":"2019-12-08 11:19:06","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2420,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.10866,"AVALU":"g/L","BASE2":2.8034,"BASE":3.10866,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.30526,"PCHG2":10.88876,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-04-28 11:19:06","ADY":142,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-12-id-185","SUBJID":"id-185","SITEID":"RUS-12","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-12","INVNAM":"Dr. RUS-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":7.67625,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-08 11:19:06","TRT01SDTM":"2019-12-08 11:19:06","AP01SDTM":"2019-12-08 11:19:06","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5670,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.15979,"AVALU":"g/L","BASE2":2.8034,"BASE":3.10866,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.35638,"PCHG2":12.71252,"CHG":0.05113,"PCHG":1.64468,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"3","BTOXGR":"1","ADTM":"2020-05-18 11:19:06","ADY":162,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-12-id-185","SUBJID":"id-185","SITEID":"RUS-12","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-12","INVNAM":"Dr. RUS-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":7.67625,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-08 11:19:06","TRT01SDTM":"2019-12-08 11:19:06","AP01SDTM":"2019-12-08 11:19:06","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":345,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89469,"AVALU":"g/L","BASE2":2.8034,"BASE":3.10866,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09129,"PCHG2":3.25631,"CHG":-0.21397,"PCHG":-6.88298,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-07-29 11:19:06","ADY":234,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-12-id-185","SUBJID":"id-185","SITEID":"RUS-12","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-12","INVNAM":"Dr. RUS-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":7.67625,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-08 11:19:06","TRT01SDTM":"2019-12-08 11:19:06","AP01SDTM":"2019-12-08 11:19:06","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3161,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78003,"AVALU":"g/L","BASE2":2.8034,"BASE":3.10866,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02338,"PCHG2":-0.83388,"CHG":-0.32863,"PCHG":-10.57153,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-09-26 11:19:06","ADY":293,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-12-id-185","SUBJID":"id-185","SITEID":"RUS-12","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-12","INVNAM":"Dr. RUS-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":7.67625,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-08 11:19:06","TRT01SDTM":"2019-12-08 11:19:06","AP01SDTM":"2019-12-08 11:19:06","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1631,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.14715,"AVALU":"g/L","BASE2":2.8034,"BASE":3.10866,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.34374,"PCHG2":12.26166,"CHG":0.03849,"PCHG":1.23809,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"1","ADTM":"2021-04-30 11:19:06","ADY":509,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-12-id-185","SUBJID":"id-185","SITEID":"RUS-12","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-12","INVNAM":"Dr. RUS-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":7.67625,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-04","TRTSDTM":"2019-12-08 11:19:06","TRT01SDTM":"2019-12-08 11:19:06","AP01SDTM":"2019-12-08 11:19:06","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7717,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82551,"AVALU":"g/L","BASE2":2.8034,"BASE":3.10866,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02211,"PCHG2":0.78856,"CHG":-0.28315,"PCHG":-9.10841,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-09-18 11:19:06","ADY":650,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-13-id-70","SUBJID":"id-70","SITEID":"RUS-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-13","INVNAM":"Dr. RUS-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.48732,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-15","TRTSDTM":"2019-04-15 01:39:32","TRTEDTM":"2022-04-14 19:39:32","TRT01SDTM":"2019-04-15 01:39:32","TRT01EDTM":"2021-04-14 13:39:32","TRT02SDTM":"2021-04-14 13:39:32","TRT02EDTM":"2022-04-14 19:39:32","AP01SDTM":"2019-04-15 01:39:32","AP01EDTM":"2021-04-14 13:39:32","AP02SDTM":"2021-04-14 13:39:32","AP02EDTM":"2022-04-14 19:39:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-14","EOSDY":1096,"LSTALVDT":"2022-05-05","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6153,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.44204,"AVALU":"U/L","BASE2":16.44204,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-05-08 01:39:32","ADY":23,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-13-id-70","SUBJID":"id-70","SITEID":"RUS-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-13","INVNAM":"Dr. RUS-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.48732,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-15","TRTSDTM":"2019-04-15 01:39:32","TRTEDTM":"2022-04-14 19:39:32","TRT01SDTM":"2019-04-15 01:39:32","TRT01EDTM":"2021-04-14 13:39:32","TRT02SDTM":"2021-04-14 13:39:32","TRT02EDTM":"2022-04-14 19:39:32","AP01SDTM":"2019-04-15 01:39:32","AP01EDTM":"2021-04-14 13:39:32","AP02SDTM":"2021-04-14 13:39:32","AP02EDTM":"2022-04-14 19:39:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-14","EOSDY":1096,"LSTALVDT":"2022-05-05","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4731,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.94229,"AVALU":"U/L","BASE2":16.44204,"BASE":10.94229,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-5.49976,"PCHG2":-33.44936,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-12 01:39:32","ADY":241,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-13-id-70","SUBJID":"id-70","SITEID":"RUS-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-13","INVNAM":"Dr. RUS-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.48732,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-15","TRTSDTM":"2019-04-15 01:39:32","TRTEDTM":"2022-04-14 19:39:32","TRT01SDTM":"2019-04-15 01:39:32","TRT01EDTM":"2021-04-14 13:39:32","TRT02SDTM":"2021-04-14 13:39:32","TRT02EDTM":"2022-04-14 19:39:32","AP01SDTM":"2019-04-15 01:39:32","AP01EDTM":"2021-04-14 13:39:32","AP02SDTM":"2021-04-14 13:39:32","AP02EDTM":"2022-04-14 19:39:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-14","EOSDY":1096,"LSTALVDT":"2022-05-05","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3869,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.57301,"AVALU":"U/L","BASE2":16.44204,"BASE":10.94229,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.86903,"PCHG2":-66.1051,"CHG":-5.36927,"PCHG":-49.06901,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-01-01 01:39:32","ADY":261,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-13-id-70","SUBJID":"id-70","SITEID":"RUS-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-13","INVNAM":"Dr. RUS-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.48732,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-15","TRTSDTM":"2019-04-15 01:39:32","TRTEDTM":"2022-04-14 19:39:32","TRT01SDTM":"2019-04-15 01:39:32","TRT01EDTM":"2021-04-14 13:39:32","TRT02SDTM":"2021-04-14 13:39:32","TRT02EDTM":"2022-04-14 19:39:32","AP01SDTM":"2019-04-15 01:39:32","AP01EDTM":"2021-04-14 13:39:32","AP02SDTM":"2021-04-14 13:39:32","AP02EDTM":"2022-04-14 19:39:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-14","EOSDY":1096,"LSTALVDT":"2022-05-05","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6079,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.48696,"AVALU":"U/L","BASE2":16.44204,"BASE":10.94229,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.95508,"PCHG2":-90.95633,"CHG":-9.45532,"PCHG":-86.41084,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-02-29 01:39:32","ADY":320,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-13-id-70","SUBJID":"id-70","SITEID":"RUS-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-13","INVNAM":"Dr. RUS-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.48732,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-15","TRTSDTM":"2019-04-15 01:39:32","TRTEDTM":"2022-04-14 19:39:32","TRT01SDTM":"2019-04-15 01:39:32","TRT01EDTM":"2021-04-14 13:39:32","TRT02SDTM":"2021-04-14 13:39:32","TRT02EDTM":"2022-04-14 19:39:32","AP01SDTM":"2019-04-15 01:39:32","AP01EDTM":"2021-04-14 13:39:32","AP02SDTM":"2021-04-14 13:39:32","AP02EDTM":"2022-04-14 19:39:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-14","EOSDY":1096,"LSTALVDT":"2022-05-05","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3218,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.41466,"AVALU":"U/L","BASE2":16.44204,"BASE":10.94229,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.97261,"PCHG2":78.89903,"CHG":18.47237,"PCHG":168.81641,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-22 01:39:32","ADY":403,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-13-id-70","SUBJID":"id-70","SITEID":"RUS-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-13","INVNAM":"Dr. RUS-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.48732,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-15","TRTSDTM":"2019-04-15 01:39:32","TRTEDTM":"2022-04-14 19:39:32","TRT01SDTM":"2019-04-15 01:39:32","TRT01EDTM":"2021-04-14 13:39:32","TRT02SDTM":"2021-04-14 13:39:32","TRT02EDTM":"2022-04-14 19:39:32","AP01SDTM":"2019-04-15 01:39:32","AP01EDTM":"2021-04-14 13:39:32","AP02SDTM":"2021-04-14 13:39:32","AP02EDTM":"2022-04-14 19:39:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-14","EOSDY":1096,"LSTALVDT":"2022-05-05","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1519,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.32124,"AVALU":"U/L","BASE2":16.44204,"BASE":10.94229,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.8792,"PCHG2":60.08497,"CHG":15.37896,"PCHG":140.54611,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-29 01:39:32","ADY":836,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-13-id-70","SUBJID":"id-70","SITEID":"RUS-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-13","INVNAM":"Dr. RUS-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.48732,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-15","TRTSDTM":"2019-04-15 01:39:32","TRTEDTM":"2022-04-14 19:39:32","TRT01SDTM":"2019-04-15 01:39:32","TRT01EDTM":"2021-04-14 13:39:32","TRT02SDTM":"2021-04-14 13:39:32","TRT02EDTM":"2022-04-14 19:39:32","AP01SDTM":"2019-04-15 01:39:32","AP01EDTM":"2021-04-14 13:39:32","AP02SDTM":"2021-04-14 13:39:32","AP02EDTM":"2022-04-14 19:39:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-14","EOSDY":1096,"LSTALVDT":"2022-05-05","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4755,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.66036,"AVALU":"U/L","BASE2":16.44204,"BASE":10.94229,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.78168,"PCHG2":-41.24597,"CHG":-1.28192,"PCHG":-11.71529,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-22 01:39:32","ADY":952,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-13-id-70","SUBJID":"id-70","SITEID":"RUS-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-13","INVNAM":"Dr. RUS-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.48732,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-15","TRTSDTM":"2019-04-15 01:39:32","TRTEDTM":"2022-04-14 19:39:32","TRT01SDTM":"2019-04-15 01:39:32","TRT01EDTM":"2021-04-14 13:39:32","TRT02SDTM":"2021-04-14 13:39:32","TRT02EDTM":"2022-04-14 19:39:32","AP01SDTM":"2019-04-15 01:39:32","AP01EDTM":"2021-04-14 13:39:32","AP02SDTM":"2021-04-14 13:39:32","AP02EDTM":"2022-04-14 19:39:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-14","EOSDY":1096,"LSTALVDT":"2022-05-05","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6980,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.9749,"AVALU":"mg/L","BASE2":9.9749,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-05-08 01:39:32","ADY":23,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-13-id-70","SUBJID":"id-70","SITEID":"RUS-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-13","INVNAM":"Dr. RUS-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.48732,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-15","TRTSDTM":"2019-04-15 01:39:32","TRTEDTM":"2022-04-14 19:39:32","TRT01SDTM":"2019-04-15 01:39:32","TRT01EDTM":"2021-04-14 13:39:32","TRT02SDTM":"2021-04-14 13:39:32","TRT02EDTM":"2022-04-14 19:39:32","AP01SDTM":"2019-04-15 01:39:32","AP01EDTM":"2021-04-14 13:39:32","AP02SDTM":"2021-04-14 13:39:32","AP02EDTM":"2022-04-14 19:39:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-14","EOSDY":1096,"LSTALVDT":"2022-05-05","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4310,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.58024,"AVALU":"mg/L","BASE2":9.9749,"BASE":8.58024,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.39466,"PCHG2":-13.98173,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-12 01:39:32","ADY":241,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-13-id-70","SUBJID":"id-70","SITEID":"RUS-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-13","INVNAM":"Dr. RUS-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.48732,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-15","TRTSDTM":"2019-04-15 01:39:32","TRTEDTM":"2022-04-14 19:39:32","TRT01SDTM":"2019-04-15 01:39:32","TRT01EDTM":"2021-04-14 13:39:32","TRT02SDTM":"2021-04-14 13:39:32","TRT02EDTM":"2022-04-14 19:39:32","AP01SDTM":"2019-04-15 01:39:32","AP01EDTM":"2021-04-14 13:39:32","AP02SDTM":"2021-04-14 13:39:32","AP02EDTM":"2022-04-14 19:39:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-14","EOSDY":1096,"LSTALVDT":"2022-05-05","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":410,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.21034,"AVALU":"mg/L","BASE2":9.9749,"BASE":8.58024,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.76456,"PCHG2":-17.68997,"CHG":-0.36989,"PCHG":-4.311,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-01 01:39:32","ADY":261,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-13-id-70","SUBJID":"id-70","SITEID":"RUS-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-13","INVNAM":"Dr. RUS-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.48732,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-15","TRTSDTM":"2019-04-15 01:39:32","TRTEDTM":"2022-04-14 19:39:32","TRT01SDTM":"2019-04-15 01:39:32","TRT01EDTM":"2021-04-14 13:39:32","TRT02SDTM":"2021-04-14 13:39:32","TRT02EDTM":"2022-04-14 19:39:32","AP01SDTM":"2019-04-15 01:39:32","AP01EDTM":"2021-04-14 13:39:32","AP02SDTM":"2021-04-14 13:39:32","AP02EDTM":"2022-04-14 19:39:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-14","EOSDY":1096,"LSTALVDT":"2022-05-05","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":653,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.01354,"AVALU":"mg/L","BASE2":9.9749,"BASE":8.58024,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.96136,"PCHG2":-19.66297,"CHG":-0.5667,"PCHG":-6.60469,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-29 01:39:32","ADY":320,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-13-id-70","SUBJID":"id-70","SITEID":"RUS-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-13","INVNAM":"Dr. RUS-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.48732,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-15","TRTSDTM":"2019-04-15 01:39:32","TRTEDTM":"2022-04-14 19:39:32","TRT01SDTM":"2019-04-15 01:39:32","TRT01EDTM":"2021-04-14 13:39:32","TRT02SDTM":"2021-04-14 13:39:32","TRT02EDTM":"2022-04-14 19:39:32","AP01SDTM":"2019-04-15 01:39:32","AP01EDTM":"2021-04-14 13:39:32","AP02SDTM":"2021-04-14 13:39:32","AP02EDTM":"2022-04-14 19:39:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-14","EOSDY":1096,"LSTALVDT":"2022-05-05","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3055,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.62011,"AVALU":"mg/L","BASE2":9.9749,"BASE":8.58024,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.35479,"PCHG2":-3.55681,"CHG":1.03988,"PCHG":12.11942,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-22 01:39:32","ADY":403,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-13-id-70","SUBJID":"id-70","SITEID":"RUS-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-13","INVNAM":"Dr. RUS-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.48732,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-15","TRTSDTM":"2019-04-15 01:39:32","TRTEDTM":"2022-04-14 19:39:32","TRT01SDTM":"2019-04-15 01:39:32","TRT01EDTM":"2021-04-14 13:39:32","TRT02SDTM":"2021-04-14 13:39:32","TRT02EDTM":"2022-04-14 19:39:32","AP01SDTM":"2019-04-15 01:39:32","AP01EDTM":"2021-04-14 13:39:32","AP02SDTM":"2021-04-14 13:39:32","AP02EDTM":"2022-04-14 19:39:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-14","EOSDY":1096,"LSTALVDT":"2022-05-05","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1876,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.68105,"AVALU":"mg/L","BASE2":9.9749,"BASE":8.58024,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.29385,"PCHG2":-2.94589,"CHG":1.10081,"PCHG":12.82964,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-29 01:39:32","ADY":836,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-13-id-70","SUBJID":"id-70","SITEID":"RUS-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-13","INVNAM":"Dr. RUS-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.48732,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-15","TRTSDTM":"2019-04-15 01:39:32","TRTEDTM":"2022-04-14 19:39:32","TRT01SDTM":"2019-04-15 01:39:32","TRT01EDTM":"2021-04-14 13:39:32","TRT02SDTM":"2021-04-14 13:39:32","TRT02EDTM":"2022-04-14 19:39:32","AP01SDTM":"2019-04-15 01:39:32","AP01EDTM":"2021-04-14 13:39:32","AP02SDTM":"2021-04-14 13:39:32","AP02EDTM":"2022-04-14 19:39:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-14","EOSDY":1096,"LSTALVDT":"2022-05-05","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5150,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.95841,"AVALU":"mg/L","BASE2":9.9749,"BASE":8.58024,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.01649,"PCHG2":-10.19051,"CHG":0.37817,"PCHG":4.40745,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-22 01:39:32","ADY":952,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-13-id-70","SUBJID":"id-70","SITEID":"RUS-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-13","INVNAM":"Dr. RUS-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.48732,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-15","TRTSDTM":"2019-04-15 01:39:32","TRTEDTM":"2022-04-14 19:39:32","TRT01SDTM":"2019-04-15 01:39:32","TRT01EDTM":"2021-04-14 13:39:32","TRT02SDTM":"2021-04-14 13:39:32","TRT02EDTM":"2022-04-14 19:39:32","AP01SDTM":"2019-04-15 01:39:32","AP01EDTM":"2021-04-14 13:39:32","AP02SDTM":"2021-04-14 13:39:32","AP02EDTM":"2022-04-14 19:39:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-14","EOSDY":1096,"LSTALVDT":"2022-05-05","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6186,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94788,"AVALU":"g/L","BASE2":2.94788,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-05-08 01:39:32","ADY":23,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-13-id-70","SUBJID":"id-70","SITEID":"RUS-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-13","INVNAM":"Dr. RUS-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.48732,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-15","TRTSDTM":"2019-04-15 01:39:32","TRTEDTM":"2022-04-14 19:39:32","TRT01SDTM":"2019-04-15 01:39:32","TRT01EDTM":"2021-04-14 13:39:32","TRT02SDTM":"2021-04-14 13:39:32","TRT02EDTM":"2022-04-14 19:39:32","AP01SDTM":"2019-04-15 01:39:32","AP01EDTM":"2021-04-14 13:39:32","AP02SDTM":"2021-04-14 13:39:32","AP02EDTM":"2022-04-14 19:39:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-14","EOSDY":1096,"LSTALVDT":"2022-05-05","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7460,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8939,"AVALU":"g/L","BASE2":2.94788,"BASE":2.8939,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.05398,"PCHG2":-1.83129,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-12 01:39:32","ADY":241,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-13-id-70","SUBJID":"id-70","SITEID":"RUS-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-13","INVNAM":"Dr. RUS-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.48732,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-15","TRTSDTM":"2019-04-15 01:39:32","TRTEDTM":"2022-04-14 19:39:32","TRT01SDTM":"2019-04-15 01:39:32","TRT01EDTM":"2021-04-14 13:39:32","TRT02SDTM":"2021-04-14 13:39:32","TRT02EDTM":"2022-04-14 19:39:32","AP01SDTM":"2019-04-15 01:39:32","AP01EDTM":"2021-04-14 13:39:32","AP02SDTM":"2021-04-14 13:39:32","AP02EDTM":"2022-04-14 19:39:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-14","EOSDY":1096,"LSTALVDT":"2022-05-05","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6723,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90794,"AVALU":"g/L","BASE2":2.94788,"BASE":2.8939,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03995,"PCHG2":-1.35518,"CHG":0.01404,"PCHG":0.48499,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-01 01:39:32","ADY":261,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-13-id-70","SUBJID":"id-70","SITEID":"RUS-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-13","INVNAM":"Dr. RUS-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.48732,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-15","TRTSDTM":"2019-04-15 01:39:32","TRTEDTM":"2022-04-14 19:39:32","TRT01SDTM":"2019-04-15 01:39:32","TRT01EDTM":"2021-04-14 13:39:32","TRT02SDTM":"2021-04-14 13:39:32","TRT02EDTM":"2022-04-14 19:39:32","AP01SDTM":"2019-04-15 01:39:32","AP01EDTM":"2021-04-14 13:39:32","AP02SDTM":"2021-04-14 13:39:32","AP02EDTM":"2022-04-14 19:39:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-14","EOSDY":1096,"LSTALVDT":"2022-05-05","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5201,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.16462,"AVALU":"g/L","BASE2":2.94788,"BASE":2.8939,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.21674,"PCHG2":7.35226,"CHG":0.27072,"PCHG":9.35486,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-02-29 01:39:32","ADY":320,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-13-id-70","SUBJID":"id-70","SITEID":"RUS-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-13","INVNAM":"Dr. RUS-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.48732,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-15","TRTSDTM":"2019-04-15 01:39:32","TRTEDTM":"2022-04-14 19:39:32","TRT01SDTM":"2019-04-15 01:39:32","TRT01EDTM":"2021-04-14 13:39:32","TRT02SDTM":"2021-04-14 13:39:32","TRT02EDTM":"2022-04-14 19:39:32","AP01SDTM":"2019-04-15 01:39:32","AP01EDTM":"2021-04-14 13:39:32","AP02SDTM":"2021-04-14 13:39:32","AP02EDTM":"2022-04-14 19:39:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-14","EOSDY":1096,"LSTALVDT":"2022-05-05","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7539,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.73917,"AVALU":"g/L","BASE2":2.94788,"BASE":2.8939,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20872,"PCHG2":-7.08026,"CHG":-0.15473,"PCHG":-5.34688,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-22 01:39:32","ADY":403,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-13-id-70","SUBJID":"id-70","SITEID":"RUS-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-13","INVNAM":"Dr. RUS-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.48732,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-15","TRTSDTM":"2019-04-15 01:39:32","TRTEDTM":"2022-04-14 19:39:32","TRT01SDTM":"2019-04-15 01:39:32","TRT01EDTM":"2021-04-14 13:39:32","TRT02SDTM":"2021-04-14 13:39:32","TRT02EDTM":"2022-04-14 19:39:32","AP01SDTM":"2019-04-15 01:39:32","AP01EDTM":"2021-04-14 13:39:32","AP02SDTM":"2021-04-14 13:39:32","AP02EDTM":"2022-04-14 19:39:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-14","EOSDY":1096,"LSTALVDT":"2022-05-05","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3094,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97326,"AVALU":"g/L","BASE2":2.94788,"BASE":2.8939,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02537,"PCHG2":0.86064,"CHG":0.07936,"PCHG":2.74215,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-29 01:39:32","ADY":836,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-13-id-70","SUBJID":"id-70","SITEID":"RUS-13","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-13","INVNAM":"Dr. RUS-13 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.48732,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-15","TRTSDTM":"2019-04-15 01:39:32","TRTEDTM":"2022-04-14 19:39:32","TRT01SDTM":"2019-04-15 01:39:32","TRT01EDTM":"2021-04-14 13:39:32","TRT02SDTM":"2021-04-14 13:39:32","TRT02EDTM":"2022-04-14 19:39:32","AP01SDTM":"2019-04-15 01:39:32","AP01EDTM":"2021-04-14 13:39:32","AP02SDTM":"2021-04-14 13:39:32","AP02EDTM":"2022-04-14 19:39:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-14","EOSDY":1096,"LSTALVDT":"2022-05-05","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6514,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88557,"AVALU":"g/L","BASE2":2.94788,"BASE":2.8939,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06231,"PCHG2":-2.11389,"CHG":-0.00833,"PCHG":-0.28787,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-22 01:39:32","ADY":952,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-14-id-183","SUBJID":"id-183","SITEID":"RUS-14","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-14","INVNAM":"Dr. RUS-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19605,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-23","TRTSDTM":"2019-08-27 23:04:32","TRTEDTM":"2022-08-27 17:04:32","TRT01SDTM":"2019-08-27 23:04:32","TRT01EDTM":"2021-08-27 11:04:32","TRT02SDTM":"2021-08-27 11:04:32","TRT02EDTM":"2022-08-27 17:04:32","AP01SDTM":"2019-08-27 23:04:32","AP01EDTM":"2021-08-27 11:04:32","AP02SDTM":"2021-08-27 11:04:32","AP02EDTM":"2022-08-27 17:04:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-27","EOSDY":1096,"LSTALVDT":"2022-09-12","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4567,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.67099,"AVALU":"U/L","BASE2":20.67099,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-04 23:04:32","ADY":161,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-14-id-183","SUBJID":"id-183","SITEID":"RUS-14","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-14","INVNAM":"Dr. RUS-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19605,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-23","TRTSDTM":"2019-08-27 23:04:32","TRTEDTM":"2022-08-27 17:04:32","TRT01SDTM":"2019-08-27 23:04:32","TRT01EDTM":"2021-08-27 11:04:32","TRT02SDTM":"2021-08-27 11:04:32","TRT02EDTM":"2022-08-27 17:04:32","AP01SDTM":"2019-08-27 23:04:32","AP01EDTM":"2021-08-27 11:04:32","AP02SDTM":"2021-08-27 11:04:32","AP02EDTM":"2022-08-27 17:04:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-27","EOSDY":1096,"LSTALVDT":"2022-09-12","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1487,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.07944,"AVALU":"U/L","BASE2":20.67099,"BASE":22.07944,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.40845,"PCHG2":6.81367,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-28 23:04:32","ADY":306,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-14-id-183","SUBJID":"id-183","SITEID":"RUS-14","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-14","INVNAM":"Dr. RUS-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19605,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-23","TRTSDTM":"2019-08-27 23:04:32","TRTEDTM":"2022-08-27 17:04:32","TRT01SDTM":"2019-08-27 23:04:32","TRT01EDTM":"2021-08-27 11:04:32","TRT02SDTM":"2021-08-27 11:04:32","TRT02EDTM":"2022-08-27 17:04:32","AP01SDTM":"2019-08-27 23:04:32","AP01EDTM":"2021-08-27 11:04:32","AP02SDTM":"2021-08-27 11:04:32","AP02EDTM":"2022-08-27 17:04:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-27","EOSDY":1096,"LSTALVDT":"2022-09-12","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6756,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.8831,"AVALU":"U/L","BASE2":20.67099,"BASE":22.07944,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.21211,"PCHG2":20.37694,"CHG":2.80366,"PCHG":12.69806,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-03 23:04:32","ADY":403,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-14-id-183","SUBJID":"id-183","SITEID":"RUS-14","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-14","INVNAM":"Dr. RUS-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19605,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-23","TRTSDTM":"2019-08-27 23:04:32","TRTEDTM":"2022-08-27 17:04:32","TRT01SDTM":"2019-08-27 23:04:32","TRT01EDTM":"2021-08-27 11:04:32","TRT02SDTM":"2021-08-27 11:04:32","TRT02EDTM":"2022-08-27 17:04:32","AP01SDTM":"2019-08-27 23:04:32","AP01EDTM":"2021-08-27 11:04:32","AP02SDTM":"2021-08-27 11:04:32","AP02EDTM":"2022-08-27 17:04:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-27","EOSDY":1096,"LSTALVDT":"2022-09-12","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3311,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.23017,"AVALU":"U/L","BASE2":20.67099,"BASE":22.07944,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.55918,"PCHG2":7.54285,"CHG":0.15073,"PCHG":0.68266,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-20 23:04:32","ADY":481,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-14-id-183","SUBJID":"id-183","SITEID":"RUS-14","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-14","INVNAM":"Dr. RUS-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19605,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-23","TRTSDTM":"2019-08-27 23:04:32","TRTEDTM":"2022-08-27 17:04:32","TRT01SDTM":"2019-08-27 23:04:32","TRT01EDTM":"2021-08-27 11:04:32","TRT02SDTM":"2021-08-27 11:04:32","TRT02EDTM":"2022-08-27 17:04:32","AP01SDTM":"2019-08-27 23:04:32","AP01EDTM":"2021-08-27 11:04:32","AP02SDTM":"2021-08-27 11:04:32","AP02EDTM":"2022-08-27 17:04:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-27","EOSDY":1096,"LSTALVDT":"2022-09-12","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4727,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.04741,"AVALU":"U/L","BASE2":20.67099,"BASE":22.07944,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.37642,"PCHG2":1.82103,"CHG":-1.03203,"PCHG":-4.67416,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-08 23:04:32","ADY":590,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-14-id-183","SUBJID":"id-183","SITEID":"RUS-14","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-14","INVNAM":"Dr. RUS-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19605,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-23","TRTSDTM":"2019-08-27 23:04:32","TRTEDTM":"2022-08-27 17:04:32","TRT01SDTM":"2019-08-27 23:04:32","TRT01EDTM":"2021-08-27 11:04:32","TRT02SDTM":"2021-08-27 11:04:32","TRT02EDTM":"2022-08-27 17:04:32","AP01SDTM":"2019-08-27 23:04:32","AP01EDTM":"2021-08-27 11:04:32","AP02SDTM":"2021-08-27 11:04:32","AP02EDTM":"2022-08-27 17:04:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-27","EOSDY":1096,"LSTALVDT":"2022-09-12","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2630,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.24473,"AVALU":"U/L","BASE2":20.67099,"BASE":22.07944,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.57374,"PCHG2":41.47717,"CHG":7.16529,"PCHG":32.4523,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-09 23:04:32","ADY":925,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-14-id-183","SUBJID":"id-183","SITEID":"RUS-14","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-14","INVNAM":"Dr. RUS-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19605,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-23","TRTSDTM":"2019-08-27 23:04:32","TRTEDTM":"2022-08-27 17:04:32","TRT01SDTM":"2019-08-27 23:04:32","TRT01EDTM":"2021-08-27 11:04:32","TRT02SDTM":"2021-08-27 11:04:32","TRT02EDTM":"2022-08-27 17:04:32","AP01SDTM":"2019-08-27 23:04:32","AP01EDTM":"2021-08-27 11:04:32","AP02SDTM":"2021-08-27 11:04:32","AP02EDTM":"2022-08-27 17:04:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-27","EOSDY":1096,"LSTALVDT":"2022-09-12","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2673,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.37275,"AVALU":"U/L","BASE2":20.67099,"BASE":22.07944,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.29824,"PCHG2":-54.65748,"CHG":-12.70669,"PCHG":-57.54989,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-23 23:04:32","ADY":1031,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-14-id-183","SUBJID":"id-183","SITEID":"RUS-14","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-14","INVNAM":"Dr. RUS-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19605,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-23","TRTSDTM":"2019-08-27 23:04:32","TRTEDTM":"2022-08-27 17:04:32","TRT01SDTM":"2019-08-27 23:04:32","TRT01EDTM":"2021-08-27 11:04:32","TRT02SDTM":"2021-08-27 11:04:32","TRT02EDTM":"2022-08-27 17:04:32","AP01SDTM":"2019-08-27 23:04:32","AP01EDTM":"2021-08-27 11:04:32","AP02SDTM":"2021-08-27 11:04:32","AP02EDTM":"2022-08-27 17:04:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-27","EOSDY":1096,"LSTALVDT":"2022-09-12","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3056,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.11904,"AVALU":"mg/L","BASE2":9.11904,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-3","ADTM":"2020-02-04 23:04:32","ADY":161,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-14-id-183","SUBJID":"id-183","SITEID":"RUS-14","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-14","INVNAM":"Dr. RUS-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19605,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-23","TRTSDTM":"2019-08-27 23:04:32","TRTEDTM":"2022-08-27 17:04:32","TRT01SDTM":"2019-08-27 23:04:32","TRT01EDTM":"2021-08-27 11:04:32","TRT02SDTM":"2021-08-27 11:04:32","TRT02EDTM":"2022-08-27 17:04:32","AP01SDTM":"2019-08-27 23:04:32","AP01EDTM":"2021-08-27 11:04:32","AP02SDTM":"2021-08-27 11:04:32","AP02EDTM":"2022-08-27 17:04:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-27","EOSDY":1096,"LSTALVDT":"2022-09-12","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3090,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.55917,"AVALU":"mg/L","BASE2":9.11904,"BASE":7.55917,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.55987,"PCHG2":-17.10566,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2020-06-28 23:04:32","ADY":306,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-14-id-183","SUBJID":"id-183","SITEID":"RUS-14","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-14","INVNAM":"Dr. RUS-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19605,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-23","TRTSDTM":"2019-08-27 23:04:32","TRTEDTM":"2022-08-27 17:04:32","TRT01SDTM":"2019-08-27 23:04:32","TRT01EDTM":"2021-08-27 11:04:32","TRT02SDTM":"2021-08-27 11:04:32","TRT02EDTM":"2022-08-27 17:04:32","AP01SDTM":"2019-08-27 23:04:32","AP01EDTM":"2021-08-27 11:04:32","AP02SDTM":"2021-08-27 11:04:32","AP02EDTM":"2022-08-27 17:04:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-27","EOSDY":1096,"LSTALVDT":"2022-09-12","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4882,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.38016,"AVALU":"mg/L","BASE2":9.11904,"BASE":7.55917,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.26112,"PCHG2":2.86344,"CHG":1.82099,"PCHG":24.08983,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2020-10-03 23:04:32","ADY":403,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-14-id-183","SUBJID":"id-183","SITEID":"RUS-14","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-14","INVNAM":"Dr. RUS-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19605,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-23","TRTSDTM":"2019-08-27 23:04:32","TRTEDTM":"2022-08-27 17:04:32","TRT01SDTM":"2019-08-27 23:04:32","TRT01EDTM":"2021-08-27 11:04:32","TRT02SDTM":"2021-08-27 11:04:32","TRT02EDTM":"2022-08-27 17:04:32","AP01SDTM":"2019-08-27 23:04:32","AP01EDTM":"2021-08-27 11:04:32","AP02SDTM":"2021-08-27 11:04:32","AP02EDTM":"2022-08-27 17:04:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-27","EOSDY":1096,"LSTALVDT":"2022-09-12","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6846,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.48133,"AVALU":"mg/L","BASE2":9.11904,"BASE":7.55917,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.63771,"PCHG2":-6.99319,"CHG":0.92216,"PCHG":12.19922,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2020-12-20 23:04:32","ADY":481,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-14-id-183","SUBJID":"id-183","SITEID":"RUS-14","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-14","INVNAM":"Dr. RUS-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19605,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-23","TRTSDTM":"2019-08-27 23:04:32","TRTEDTM":"2022-08-27 17:04:32","TRT01SDTM":"2019-08-27 23:04:32","TRT01EDTM":"2021-08-27 11:04:32","TRT02SDTM":"2021-08-27 11:04:32","TRT02EDTM":"2022-08-27 17:04:32","AP01SDTM":"2019-08-27 23:04:32","AP01EDTM":"2021-08-27 11:04:32","AP02SDTM":"2021-08-27 11:04:32","AP02EDTM":"2022-08-27 17:04:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-27","EOSDY":1096,"LSTALVDT":"2022-09-12","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5810,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.56383,"AVALU":"mg/L","BASE2":9.11904,"BASE":7.55917,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.44479,"PCHG2":4.87758,"CHG":2.00466,"PCHG":26.51959,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-04-08 23:04:32","ADY":590,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-14-id-183","SUBJID":"id-183","SITEID":"RUS-14","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-14","INVNAM":"Dr. RUS-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19605,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-23","TRTSDTM":"2019-08-27 23:04:32","TRTEDTM":"2022-08-27 17:04:32","TRT01SDTM":"2019-08-27 23:04:32","TRT01EDTM":"2021-08-27 11:04:32","TRT02SDTM":"2021-08-27 11:04:32","TRT02EDTM":"2022-08-27 17:04:32","AP01SDTM":"2019-08-27 23:04:32","AP01EDTM":"2021-08-27 11:04:32","AP02SDTM":"2021-08-27 11:04:32","AP02EDTM":"2022-08-27 17:04:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-27","EOSDY":1096,"LSTALVDT":"2022-09-12","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4560,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.42185,"AVALU":"mg/L","BASE2":9.11904,"BASE":7.55917,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.30281,"PCHG2":14.28669,"CHG":2.86268,"PCHG":37.87032,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"1","BTOXGR":"-3","ADTM":"2022-03-09 23:04:32","ADY":925,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-14-id-183","SUBJID":"id-183","SITEID":"RUS-14","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-14","INVNAM":"Dr. RUS-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19605,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-23","TRTSDTM":"2019-08-27 23:04:32","TRTEDTM":"2022-08-27 17:04:32","TRT01SDTM":"2019-08-27 23:04:32","TRT01EDTM":"2021-08-27 11:04:32","TRT02SDTM":"2021-08-27 11:04:32","TRT02EDTM":"2022-08-27 17:04:32","AP01SDTM":"2019-08-27 23:04:32","AP01EDTM":"2021-08-27 11:04:32","AP02SDTM":"2021-08-27 11:04:32","AP02EDTM":"2022-08-27 17:04:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-27","EOSDY":1096,"LSTALVDT":"2022-09-12","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2450,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.82227,"AVALU":"mg/L","BASE2":9.11904,"BASE":7.55917,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.29677,"PCHG2":-3.25442,"CHG":1.2631,"PCHG":16.70951,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2022-06-23 23:04:32","ADY":1031,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-14-id-183","SUBJID":"id-183","SITEID":"RUS-14","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-14","INVNAM":"Dr. RUS-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19605,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-23","TRTSDTM":"2019-08-27 23:04:32","TRTEDTM":"2022-08-27 17:04:32","TRT01SDTM":"2019-08-27 23:04:32","TRT01EDTM":"2021-08-27 11:04:32","TRT02SDTM":"2021-08-27 11:04:32","TRT02EDTM":"2022-08-27 17:04:32","AP01SDTM":"2019-08-27 23:04:32","AP01EDTM":"2021-08-27 11:04:32","AP02SDTM":"2021-08-27 11:04:32","AP02EDTM":"2022-08-27 17:04:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-27","EOSDY":1096,"LSTALVDT":"2022-09-12","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6286,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87848,"AVALU":"g/L","BASE2":2.87848,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-04 23:04:32","ADY":161,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-14-id-183","SUBJID":"id-183","SITEID":"RUS-14","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-14","INVNAM":"Dr. RUS-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19605,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-23","TRTSDTM":"2019-08-27 23:04:32","TRTEDTM":"2022-08-27 17:04:32","TRT01SDTM":"2019-08-27 23:04:32","TRT01EDTM":"2021-08-27 11:04:32","TRT02SDTM":"2021-08-27 11:04:32","TRT02EDTM":"2022-08-27 17:04:32","AP01SDTM":"2019-08-27 23:04:32","AP01EDTM":"2021-08-27 11:04:32","AP02SDTM":"2021-08-27 11:04:32","AP02EDTM":"2022-08-27 17:04:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-27","EOSDY":1096,"LSTALVDT":"2022-09-12","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5719,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75255,"AVALU":"g/L","BASE2":2.87848,"BASE":2.75255,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.12593,"PCHG2":-4.37492,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-28 23:04:32","ADY":306,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-14-id-183","SUBJID":"id-183","SITEID":"RUS-14","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-14","INVNAM":"Dr. RUS-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19605,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-23","TRTSDTM":"2019-08-27 23:04:32","TRTEDTM":"2022-08-27 17:04:32","TRT01SDTM":"2019-08-27 23:04:32","TRT01EDTM":"2021-08-27 11:04:32","TRT02SDTM":"2021-08-27 11:04:32","TRT02EDTM":"2022-08-27 17:04:32","AP01SDTM":"2019-08-27 23:04:32","AP01EDTM":"2021-08-27 11:04:32","AP02SDTM":"2021-08-27 11:04:32","AP02EDTM":"2022-08-27 17:04:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-27","EOSDY":1096,"LSTALVDT":"2022-09-12","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":931,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.70786,"AVALU":"g/L","BASE2":2.87848,"BASE":2.75255,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17062,"PCHG2":-5.92734,"CHG":-0.04469,"PCHG":-1.62345,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-03 23:04:32","ADY":403,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-14-id-183","SUBJID":"id-183","SITEID":"RUS-14","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-14","INVNAM":"Dr. RUS-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19605,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-23","TRTSDTM":"2019-08-27 23:04:32","TRTEDTM":"2022-08-27 17:04:32","TRT01SDTM":"2019-08-27 23:04:32","TRT01EDTM":"2021-08-27 11:04:32","TRT02SDTM":"2021-08-27 11:04:32","TRT02EDTM":"2022-08-27 17:04:32","AP01SDTM":"2019-08-27 23:04:32","AP01EDTM":"2021-08-27 11:04:32","AP02SDTM":"2021-08-27 11:04:32","AP02EDTM":"2022-08-27 17:04:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-27","EOSDY":1096,"LSTALVDT":"2022-09-12","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7402,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83038,"AVALU":"g/L","BASE2":2.87848,"BASE":2.75255,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0481,"PCHG2":-1.67087,"CHG":0.07784,"PCHG":2.82776,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-20 23:04:32","ADY":481,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-14-id-183","SUBJID":"id-183","SITEID":"RUS-14","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-14","INVNAM":"Dr. RUS-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19605,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-23","TRTSDTM":"2019-08-27 23:04:32","TRTEDTM":"2022-08-27 17:04:32","TRT01SDTM":"2019-08-27 23:04:32","TRT01EDTM":"2021-08-27 11:04:32","TRT02SDTM":"2021-08-27 11:04:32","TRT02EDTM":"2022-08-27 17:04:32","AP01SDTM":"2019-08-27 23:04:32","AP01EDTM":"2021-08-27 11:04:32","AP02SDTM":"2021-08-27 11:04:32","AP02EDTM":"2022-08-27 17:04:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-27","EOSDY":1096,"LSTALVDT":"2022-09-12","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5079,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0222,"AVALU":"g/L","BASE2":2.87848,"BASE":2.75255,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14372,"PCHG2":4.99303,"CHG":0.26965,"PCHG":9.79654,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2021-04-08 23:04:32","ADY":590,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-14-id-183","SUBJID":"id-183","SITEID":"RUS-14","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-14","INVNAM":"Dr. RUS-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19605,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-23","TRTSDTM":"2019-08-27 23:04:32","TRTEDTM":"2022-08-27 17:04:32","TRT01SDTM":"2019-08-27 23:04:32","TRT01EDTM":"2021-08-27 11:04:32","TRT02SDTM":"2021-08-27 11:04:32","TRT02EDTM":"2022-08-27 17:04:32","AP01SDTM":"2019-08-27 23:04:32","AP01EDTM":"2021-08-27 11:04:32","AP02SDTM":"2021-08-27 11:04:32","AP02EDTM":"2022-08-27 17:04:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-27","EOSDY":1096,"LSTALVDT":"2022-09-12","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4080,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98743,"AVALU":"g/L","BASE2":2.87848,"BASE":2.75255,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10895,"PCHG2":3.78506,"CHG":0.23488,"PCHG":8.5333,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-09 23:04:32","ADY":925,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-14-id-183","SUBJID":"id-183","SITEID":"RUS-14","AGE":28,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-14","INVNAM":"Dr. RUS-14 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":4.19605,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-08-23","TRTSDTM":"2019-08-27 23:04:32","TRTEDTM":"2022-08-27 17:04:32","TRT01SDTM":"2019-08-27 23:04:32","TRT01EDTM":"2021-08-27 11:04:32","TRT02SDTM":"2021-08-27 11:04:32","TRT02EDTM":"2022-08-27 17:04:32","AP01SDTM":"2019-08-27 23:04:32","AP01EDTM":"2021-08-27 11:04:32","AP02SDTM":"2021-08-27 11:04:32","AP02EDTM":"2022-08-27 17:04:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-27","EOSDY":1096,"LSTALVDT":"2022-09-12","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4274,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.09304,"AVALU":"g/L","BASE2":2.87848,"BASE":2.75255,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.21457,"PCHG2":7.45418,"CHG":0.3405,"PCHG":12.37029,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-06-23 23:04:32","ADY":1031,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-165","SUBJID":"id-165","SITEID":"RUS-16","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.49284,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-04","TRTSDTM":"2020-07-06 15:51:46","TRTEDTM":"2023-07-07 09:51:46","TRT01SDTM":"2020-07-06 15:51:46","TRT01EDTM":"2022-07-07 03:51:46","TRT02SDTM":"2022-07-07 03:51:46","TRT02EDTM":"2023-07-07 09:51:46","AP01SDTM":"2020-07-06 15:51:46","AP01EDTM":"2022-07-07 03:51:46","AP02SDTM":"2022-07-07 03:51:46","AP02EDTM":"2023-07-07 09:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-07","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2621,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.89124,"AVALU":"U/L","BASE2":4.89124,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-10-20 15:51:46","ADY":106,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-165","SUBJID":"id-165","SITEID":"RUS-16","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.49284,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-04","TRTSDTM":"2020-07-06 15:51:46","TRTEDTM":"2023-07-07 09:51:46","TRT01SDTM":"2020-07-06 15:51:46","TRT01EDTM":"2022-07-07 03:51:46","TRT02SDTM":"2022-07-07 03:51:46","TRT02EDTM":"2023-07-07 09:51:46","AP01SDTM":"2020-07-06 15:51:46","AP01EDTM":"2022-07-07 03:51:46","AP02SDTM":"2022-07-07 03:51:46","AP02EDTM":"2023-07-07 09:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-07","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2730,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":35.36767,"AVALU":"U/L","BASE2":4.89124,"BASE":35.36767,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":30.47643,"PCHG2":623.08198,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-01 15:51:46","ADY":483,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-165","SUBJID":"id-165","SITEID":"RUS-16","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.49284,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-04","TRTSDTM":"2020-07-06 15:51:46","TRTEDTM":"2023-07-07 09:51:46","TRT01SDTM":"2020-07-06 15:51:46","TRT01EDTM":"2022-07-07 03:51:46","TRT02SDTM":"2022-07-07 03:51:46","TRT02EDTM":"2023-07-07 09:51:46","AP01SDTM":"2020-07-06 15:51:46","AP01EDTM":"2022-07-07 03:51:46","AP02SDTM":"2022-07-07 03:51:46","AP02EDTM":"2023-07-07 09:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-07","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1093,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.97777,"AVALU":"U/L","BASE2":4.89124,"BASE":35.36767,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.08653,"PCHG2":390.21858,"CHG":-11.38991,"PCHG":-32.20429,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-07 15:51:46","ADY":489,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-165","SUBJID":"id-165","SITEID":"RUS-16","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.49284,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-04","TRTSDTM":"2020-07-06 15:51:46","TRTEDTM":"2023-07-07 09:51:46","TRT01SDTM":"2020-07-06 15:51:46","TRT01EDTM":"2022-07-07 03:51:46","TRT02SDTM":"2022-07-07 03:51:46","TRT02EDTM":"2023-07-07 09:51:46","AP01SDTM":"2020-07-06 15:51:46","AP01EDTM":"2022-07-07 03:51:46","AP02SDTM":"2022-07-07 03:51:46","AP02EDTM":"2023-07-07 09:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-07","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4990,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.50636,"AVALU":"U/L","BASE2":4.89124,"BASE":35.36767,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.61512,"PCHG2":114.79953,"CHG":-24.86131,"PCHG":-70.29389,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-18 15:51:46","ADY":592,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-165","SUBJID":"id-165","SITEID":"RUS-16","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.49284,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-04","TRTSDTM":"2020-07-06 15:51:46","TRTEDTM":"2023-07-07 09:51:46","TRT01SDTM":"2020-07-06 15:51:46","TRT01EDTM":"2022-07-07 03:51:46","TRT02SDTM":"2022-07-07 03:51:46","TRT02EDTM":"2023-07-07 09:51:46","AP01SDTM":"2020-07-06 15:51:46","AP01EDTM":"2022-07-07 03:51:46","AP02SDTM":"2022-07-07 03:51:46","AP02EDTM":"2023-07-07 09:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-07","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8281,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.66224,"AVALU":"U/L","BASE2":4.89124,"BASE":35.36767,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.229,"PCHG2":-4.68187,"CHG":-30.70544,"PCHG":-86.8178,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-07-16 15:51:46","ADY":740,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-165","SUBJID":"id-165","SITEID":"RUS-16","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.49284,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-04","TRTSDTM":"2020-07-06 15:51:46","TRTEDTM":"2023-07-07 09:51:46","TRT01SDTM":"2020-07-06 15:51:46","TRT01EDTM":"2022-07-07 03:51:46","TRT02SDTM":"2022-07-07 03:51:46","TRT02EDTM":"2023-07-07 09:51:46","AP01SDTM":"2020-07-06 15:51:46","AP01EDTM":"2022-07-07 03:51:46","AP02SDTM":"2022-07-07 03:51:46","AP02EDTM":"2023-07-07 09:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-07","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7740,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.81613,"AVALU":"U/L","BASE2":4.89124,"BASE":35.36767,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.92489,"PCHG2":182.46686,"CHG":-21.55154,"PCHG":-60.93571,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-10 15:51:46","ADY":1038,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-165","SUBJID":"id-165","SITEID":"RUS-16","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.49284,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-04","TRTSDTM":"2020-07-06 15:51:46","TRTEDTM":"2023-07-07 09:51:46","TRT01SDTM":"2020-07-06 15:51:46","TRT01EDTM":"2022-07-07 03:51:46","TRT02SDTM":"2022-07-07 03:51:46","TRT02EDTM":"2023-07-07 09:51:46","AP01SDTM":"2020-07-06 15:51:46","AP01EDTM":"2022-07-07 03:51:46","AP02SDTM":"2022-07-07 03:51:46","AP02EDTM":"2023-07-07 09:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-07","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1534,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.0444,"AVALU":"U/L","BASE2":4.89124,"BASE":35.36767,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.15316,"PCHG2":105.35486,"CHG":-25.32328,"PCHG":-71.60006,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-27 15:51:46","ADY":1055,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-165","SUBJID":"id-165","SITEID":"RUS-16","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.49284,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-04","TRTSDTM":"2020-07-06 15:51:46","TRTEDTM":"2023-07-07 09:51:46","TRT01SDTM":"2020-07-06 15:51:46","TRT01EDTM":"2022-07-07 03:51:46","TRT02SDTM":"2022-07-07 03:51:46","TRT02EDTM":"2023-07-07 09:51:46","AP01SDTM":"2020-07-06 15:51:46","AP01EDTM":"2022-07-07 03:51:46","AP02SDTM":"2022-07-07 03:51:46","AP02EDTM":"2023-07-07 09:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-07","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7245,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.38743,"AVALU":"mg/L","BASE2":9.38743,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-20 15:51:46","ADY":106,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-165","SUBJID":"id-165","SITEID":"RUS-16","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.49284,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-04","TRTSDTM":"2020-07-06 15:51:46","TRTEDTM":"2023-07-07 09:51:46","TRT01SDTM":"2020-07-06 15:51:46","TRT01EDTM":"2022-07-07 03:51:46","TRT02SDTM":"2022-07-07 03:51:46","TRT02EDTM":"2023-07-07 09:51:46","AP01SDTM":"2020-07-06 15:51:46","AP01EDTM":"2022-07-07 03:51:46","AP02SDTM":"2022-07-07 03:51:46","AP02EDTM":"2023-07-07 09:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-07","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6041,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.36241,"AVALU":"mg/L","BASE2":9.38743,"BASE":8.36241,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.02503,"PCHG2":-10.91914,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-01 15:51:46","ADY":483,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-165","SUBJID":"id-165","SITEID":"RUS-16","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.49284,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-04","TRTSDTM":"2020-07-06 15:51:46","TRTEDTM":"2023-07-07 09:51:46","TRT01SDTM":"2020-07-06 15:51:46","TRT01EDTM":"2022-07-07 03:51:46","TRT02SDTM":"2022-07-07 03:51:46","TRT02EDTM":"2023-07-07 09:51:46","AP01SDTM":"2020-07-06 15:51:46","AP01EDTM":"2022-07-07 03:51:46","AP02SDTM":"2022-07-07 03:51:46","AP02EDTM":"2023-07-07 09:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-07","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5287,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.41803,"AVALU":"mg/L","BASE2":9.38743,"BASE":8.36241,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.96941,"PCHG2":-10.32665,"CHG":0.05562,"PCHG":0.66511,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-07 15:51:46","ADY":489,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-165","SUBJID":"id-165","SITEID":"RUS-16","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.49284,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-04","TRTSDTM":"2020-07-06 15:51:46","TRTEDTM":"2023-07-07 09:51:46","TRT01SDTM":"2020-07-06 15:51:46","TRT01EDTM":"2022-07-07 03:51:46","TRT02SDTM":"2022-07-07 03:51:46","TRT02EDTM":"2023-07-07 09:51:46","AP01SDTM":"2020-07-06 15:51:46","AP01EDTM":"2022-07-07 03:51:46","AP02SDTM":"2022-07-07 03:51:46","AP02EDTM":"2023-07-07 09:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-07","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4702,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.38953,"AVALU":"mg/L","BASE2":9.38743,"BASE":8.36241,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0021,"PCHG2":0.02233,"CHG":1.02712,"PCHG":12.28262,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-18 15:51:46","ADY":592,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-165","SUBJID":"id-165","SITEID":"RUS-16","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.49284,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-04","TRTSDTM":"2020-07-06 15:51:46","TRTEDTM":"2023-07-07 09:51:46","TRT01SDTM":"2020-07-06 15:51:46","TRT01EDTM":"2022-07-07 03:51:46","TRT02SDTM":"2022-07-07 03:51:46","TRT02EDTM":"2023-07-07 09:51:46","AP01SDTM":"2020-07-06 15:51:46","AP01EDTM":"2022-07-07 03:51:46","AP02SDTM":"2022-07-07 03:51:46","AP02EDTM":"2023-07-07 09:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-07","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5625,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.36573,"AVALU":"mg/L","BASE2":9.38743,"BASE":8.36241,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02171,"PCHG2":-0.23124,"CHG":1.00332,"PCHG":11.99798,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-16 15:51:46","ADY":740,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-165","SUBJID":"id-165","SITEID":"RUS-16","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.49284,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-04","TRTSDTM":"2020-07-06 15:51:46","TRTEDTM":"2023-07-07 09:51:46","TRT01SDTM":"2020-07-06 15:51:46","TRT01EDTM":"2022-07-07 03:51:46","TRT02SDTM":"2022-07-07 03:51:46","TRT02EDTM":"2023-07-07 09:51:46","AP01SDTM":"2020-07-06 15:51:46","AP01EDTM":"2022-07-07 03:51:46","AP02SDTM":"2022-07-07 03:51:46","AP02EDTM":"2023-07-07 09:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-07","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7503,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.95316,"AVALU":"mg/L","BASE2":9.38743,"BASE":8.36241,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.56573,"PCHG2":6.02646,"CHG":1.59076,"PCHG":19.02272,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-10 15:51:46","ADY":1038,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-165","SUBJID":"id-165","SITEID":"RUS-16","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.49284,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-04","TRTSDTM":"2020-07-06 15:51:46","TRTEDTM":"2023-07-07 09:51:46","TRT01SDTM":"2020-07-06 15:51:46","TRT01EDTM":"2022-07-07 03:51:46","TRT02SDTM":"2022-07-07 03:51:46","TRT02EDTM":"2023-07-07 09:51:46","AP01SDTM":"2020-07-06 15:51:46","AP01EDTM":"2022-07-07 03:51:46","AP02SDTM":"2022-07-07 03:51:46","AP02EDTM":"2023-07-07 09:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-07","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7193,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.83318,"AVALU":"mg/L","BASE2":9.38743,"BASE":8.36241,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.44574,"PCHG2":4.74831,"CHG":1.47077,"PCHG":17.5879,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-27 15:51:46","ADY":1055,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-165","SUBJID":"id-165","SITEID":"RUS-16","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.49284,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-04","TRTSDTM":"2020-07-06 15:51:46","TRTEDTM":"2023-07-07 09:51:46","TRT01SDTM":"2020-07-06 15:51:46","TRT01EDTM":"2022-07-07 03:51:46","TRT02SDTM":"2022-07-07 03:51:46","TRT02EDTM":"2023-07-07 09:51:46","AP01SDTM":"2020-07-06 15:51:46","AP01EDTM":"2022-07-07 03:51:46","AP02SDTM":"2022-07-07 03:51:46","AP02EDTM":"2023-07-07 09:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-07","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2947,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75012,"AVALU":"g/L","BASE2":2.75012,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-20 15:51:46","ADY":106,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-165","SUBJID":"id-165","SITEID":"RUS-16","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.49284,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-04","TRTSDTM":"2020-07-06 15:51:46","TRTEDTM":"2023-07-07 09:51:46","TRT01SDTM":"2020-07-06 15:51:46","TRT01EDTM":"2022-07-07 03:51:46","TRT02SDTM":"2022-07-07 03:51:46","TRT02EDTM":"2023-07-07 09:51:46","AP01SDTM":"2020-07-06 15:51:46","AP01EDTM":"2022-07-07 03:51:46","AP02SDTM":"2022-07-07 03:51:46","AP02EDTM":"2023-07-07 09:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-07","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4368,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94793,"AVALU":"g/L","BASE2":2.75012,"BASE":2.94793,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.19781,"PCHG2":7.1926,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-01 15:51:46","ADY":483,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-165","SUBJID":"id-165","SITEID":"RUS-16","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.49284,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-04","TRTSDTM":"2020-07-06 15:51:46","TRTEDTM":"2023-07-07 09:51:46","TRT01SDTM":"2020-07-06 15:51:46","TRT01EDTM":"2022-07-07 03:51:46","TRT02SDTM":"2022-07-07 03:51:46","TRT02EDTM":"2023-07-07 09:51:46","AP01SDTM":"2020-07-06 15:51:46","AP01EDTM":"2022-07-07 03:51:46","AP02SDTM":"2022-07-07 03:51:46","AP02EDTM":"2023-07-07 09:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-07","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7229,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95375,"AVALU":"g/L","BASE2":2.75012,"BASE":2.94793,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.20362,"PCHG2":7.40422,"CHG":0.00582,"PCHG":0.19742,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-07 15:51:46","ADY":489,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-165","SUBJID":"id-165","SITEID":"RUS-16","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.49284,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-04","TRTSDTM":"2020-07-06 15:51:46","TRTEDTM":"2023-07-07 09:51:46","TRT01SDTM":"2020-07-06 15:51:46","TRT01EDTM":"2022-07-07 03:51:46","TRT02SDTM":"2022-07-07 03:51:46","TRT02EDTM":"2023-07-07 09:51:46","AP01SDTM":"2020-07-06 15:51:46","AP01EDTM":"2022-07-07 03:51:46","AP02SDTM":"2022-07-07 03:51:46","AP02EDTM":"2023-07-07 09:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-07","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6043,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.06983,"AVALU":"g/L","BASE2":2.75012,"BASE":2.94793,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.31971,"PCHG2":11.62533,"CHG":0.12191,"PCHG":4.1353,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-02-18 15:51:46","ADY":592,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-165","SUBJID":"id-165","SITEID":"RUS-16","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.49284,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-04","TRTSDTM":"2020-07-06 15:51:46","TRTEDTM":"2023-07-07 09:51:46","TRT01SDTM":"2020-07-06 15:51:46","TRT01EDTM":"2022-07-07 03:51:46","TRT02SDTM":"2022-07-07 03:51:46","TRT02EDTM":"2023-07-07 09:51:46","AP01SDTM":"2020-07-06 15:51:46","AP01EDTM":"2022-07-07 03:51:46","AP02SDTM":"2022-07-07 03:51:46","AP02EDTM":"2023-07-07 09:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-07","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1119,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98957,"AVALU":"g/L","BASE2":2.75012,"BASE":2.94793,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.23945,"PCHG2":8.70689,"CHG":0.04164,"PCHG":1.41268,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-16 15:51:46","ADY":740,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-165","SUBJID":"id-165","SITEID":"RUS-16","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.49284,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-04","TRTSDTM":"2020-07-06 15:51:46","TRTEDTM":"2023-07-07 09:51:46","TRT01SDTM":"2020-07-06 15:51:46","TRT01EDTM":"2022-07-07 03:51:46","TRT02SDTM":"2022-07-07 03:51:46","TRT02EDTM":"2023-07-07 09:51:46","AP01SDTM":"2020-07-06 15:51:46","AP01EDTM":"2022-07-07 03:51:46","AP02SDTM":"2022-07-07 03:51:46","AP02EDTM":"2023-07-07 09:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-07","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":135,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00692,"AVALU":"g/L","BASE2":2.75012,"BASE":2.94793,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.2568,"PCHG2":9.33774,"CHG":0.05899,"PCHG":2.00121,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2023-05-10 15:51:46","ADY":1038,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-165","SUBJID":"id-165","SITEID":"RUS-16","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S2","BMRKR1":3.49284,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-04","TRTSDTM":"2020-07-06 15:51:46","TRTEDTM":"2023-07-07 09:51:46","TRT01SDTM":"2020-07-06 15:51:46","TRT01EDTM":"2022-07-07 03:51:46","TRT02SDTM":"2022-07-07 03:51:46","TRT02EDTM":"2023-07-07 09:51:46","AP01SDTM":"2020-07-06 15:51:46","AP01EDTM":"2022-07-07 03:51:46","AP02SDTM":"2022-07-07 03:51:46","AP02EDTM":"2023-07-07 09:51:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-07","EOSDY":1096,"LSTALVDT":"2023-07-21","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2004,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89066,"AVALU":"g/L","BASE2":2.75012,"BASE":2.94793,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14054,"PCHG2":5.11045,"CHG":-0.05726,"PCHG":-1.94244,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-27 15:51:46","ADY":1055,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-4","SUBJID":"id-4","SITEID":"RUS-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.7694,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-28 04:01:15","TRTEDTM":"2022-02-14 12:31:55","TRT01SDTM":"2020-03-28 04:01:15","TRT01EDTM":"2021-02-14 06:31:55","TRT02SDTM":"2021-02-14 06:31:55","TRT02EDTM":"2022-02-14 12:31:55","AP01SDTM":"2020-03-28 04:01:15","AP01EDTM":"2021-02-14 06:31:55","AP02SDTM":"2021-02-14 06:31:55","AP02EDTM":"2022-02-14 12:31:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":699,"ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8324,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.63176,"AVALU":"U/L","BASE2":20.63176,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-19 04:01:15","ADY":22,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-4","SUBJID":"id-4","SITEID":"RUS-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.7694,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-28 04:01:15","TRTEDTM":"2022-02-14 12:31:55","TRT01SDTM":"2020-03-28 04:01:15","TRT01EDTM":"2021-02-14 06:31:55","TRT02SDTM":"2021-02-14 06:31:55","TRT02EDTM":"2022-02-14 12:31:55","AP01SDTM":"2020-03-28 04:01:15","AP01EDTM":"2021-02-14 06:31:55","AP02SDTM":"2021-02-14 06:31:55","AP02EDTM":"2022-02-14 12:31:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":699,"ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1165,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.74991,"AVALU":"U/L","BASE2":20.63176,"BASE":20.74991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.11815,"PCHG2":0.57267,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-24 04:01:15","ADY":27,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-4","SUBJID":"id-4","SITEID":"RUS-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.7694,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-28 04:01:15","TRTEDTM":"2022-02-14 12:31:55","TRT01SDTM":"2020-03-28 04:01:15","TRT01EDTM":"2021-02-14 06:31:55","TRT02SDTM":"2021-02-14 06:31:55","TRT02EDTM":"2022-02-14 12:31:55","AP01SDTM":"2020-03-28 04:01:15","AP01EDTM":"2021-02-14 06:31:55","AP02SDTM":"2021-02-14 06:31:55","AP02EDTM":"2022-02-14 12:31:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":699,"ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7118,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.77452,"AVALU":"U/L","BASE2":20.63176,"BASE":20.74991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.85723,"PCHG2":-52.62389,"CHG":-10.97539,"PCHG":-52.89366,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-21 04:01:15","ADY":54,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-4","SUBJID":"id-4","SITEID":"RUS-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.7694,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-28 04:01:15","TRTEDTM":"2022-02-14 12:31:55","TRT01SDTM":"2020-03-28 04:01:15","TRT01EDTM":"2021-02-14 06:31:55","TRT02SDTM":"2021-02-14 06:31:55","TRT02EDTM":"2022-02-14 12:31:55","AP01SDTM":"2020-03-28 04:01:15","AP01EDTM":"2021-02-14 06:31:55","AP02SDTM":"2021-02-14 06:31:55","AP02EDTM":"2022-02-14 12:31:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":699,"ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8368,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.41522,"AVALU":"U/L","BASE2":20.63176,"BASE":20.74991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-19.21653,"PCHG2":-93.14055,"CHG":-19.33468,"PCHG":-93.17961,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-07-24 04:01:15","ADY":118,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-4","SUBJID":"id-4","SITEID":"RUS-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.7694,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-28 04:01:15","TRTEDTM":"2022-02-14 12:31:55","TRT01SDTM":"2020-03-28 04:01:15","TRT01EDTM":"2021-02-14 06:31:55","TRT02SDTM":"2021-02-14 06:31:55","TRT02EDTM":"2022-02-14 12:31:55","AP01SDTM":"2020-03-28 04:01:15","AP01EDTM":"2021-02-14 06:31:55","AP02SDTM":"2021-02-14 06:31:55","AP02EDTM":"2022-02-14 12:31:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":699,"ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7039,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":37.50023,"AVALU":"U/L","BASE2":20.63176,"BASE":20.74991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.86847,"PCHG2":81.75973,"CHG":16.75032,"PCHG":80.72477,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-10 04:01:15","ADY":288,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-4","SUBJID":"id-4","SITEID":"RUS-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.7694,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-28 04:01:15","TRTEDTM":"2022-02-14 12:31:55","TRT01SDTM":"2020-03-28 04:01:15","TRT01EDTM":"2021-02-14 06:31:55","TRT02SDTM":"2021-02-14 06:31:55","TRT02EDTM":"2022-02-14 12:31:55","AP01SDTM":"2020-03-28 04:01:15","AP01EDTM":"2021-02-14 06:31:55","AP02SDTM":"2021-02-14 06:31:55","AP02EDTM":"2022-02-14 12:31:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":699,"ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6135,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.62213,"AVALU":"U/L","BASE2":20.63176,"BASE":20.74991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.00963,"PCHG2":-63.05634,"CHG":-13.12778,"PCHG":-63.2667,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-31 04:01:15","ADY":674,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-4","SUBJID":"id-4","SITEID":"RUS-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.7694,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-28 04:01:15","TRTEDTM":"2022-02-14 12:31:55","TRT01SDTM":"2020-03-28 04:01:15","TRT01EDTM":"2021-02-14 06:31:55","TRT02SDTM":"2021-02-14 06:31:55","TRT02EDTM":"2022-02-14 12:31:55","AP01SDTM":"2020-03-28 04:01:15","AP01EDTM":"2021-02-14 06:31:55","AP02SDTM":"2021-02-14 06:31:55","AP02EDTM":"2022-02-14 12:31:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":699,"ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1337,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.53915,"AVALU":"U/L","BASE2":20.63176,"BASE":20.74991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.9074,"PCHG2":38.32634,"CHG":7.78925,"PCHG":37.5387,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-10 04:01:15","ADY":684,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-4","SUBJID":"id-4","SITEID":"RUS-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.7694,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-28 04:01:15","TRTEDTM":"2022-02-14 12:31:55","TRT01SDTM":"2020-03-28 04:01:15","TRT01EDTM":"2021-02-14 06:31:55","TRT02SDTM":"2021-02-14 06:31:55","TRT02EDTM":"2022-02-14 12:31:55","AP01SDTM":"2020-03-28 04:01:15","AP01EDTM":"2021-02-14 06:31:55","AP02SDTM":"2021-02-14 06:31:55","AP02EDTM":"2022-02-14 12:31:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":699,"ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":174,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.35819,"AVALU":"mg/L","BASE2":8.35819,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-19 04:01:15","ADY":22,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-4","SUBJID":"id-4","SITEID":"RUS-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.7694,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-28 04:01:15","TRTEDTM":"2022-02-14 12:31:55","TRT01SDTM":"2020-03-28 04:01:15","TRT01EDTM":"2021-02-14 06:31:55","TRT02SDTM":"2021-02-14 06:31:55","TRT02EDTM":"2022-02-14 12:31:55","AP01SDTM":"2020-03-28 04:01:15","AP01EDTM":"2021-02-14 06:31:55","AP02SDTM":"2021-02-14 06:31:55","AP02EDTM":"2022-02-14 12:31:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":699,"ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1607,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.70012,"AVALU":"mg/L","BASE2":8.35819,"BASE":8.70012,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.34193,"PCHG2":4.09097,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-24 04:01:15","ADY":27,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-4","SUBJID":"id-4","SITEID":"RUS-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.7694,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-28 04:01:15","TRTEDTM":"2022-02-14 12:31:55","TRT01SDTM":"2020-03-28 04:01:15","TRT01EDTM":"2021-02-14 06:31:55","TRT02SDTM":"2021-02-14 06:31:55","TRT02EDTM":"2022-02-14 12:31:55","AP01SDTM":"2020-03-28 04:01:15","AP01EDTM":"2021-02-14 06:31:55","AP02SDTM":"2021-02-14 06:31:55","AP02EDTM":"2022-02-14 12:31:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":699,"ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1413,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.14988,"AVALU":"mg/L","BASE2":8.35819,"BASE":8.70012,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.2083,"PCHG2":-2.49222,"CHG":-0.55024,"PCHG":-6.32446,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-21 04:01:15","ADY":54,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-4","SUBJID":"id-4","SITEID":"RUS-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.7694,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-28 04:01:15","TRTEDTM":"2022-02-14 12:31:55","TRT01SDTM":"2020-03-28 04:01:15","TRT01EDTM":"2021-02-14 06:31:55","TRT02SDTM":"2021-02-14 06:31:55","TRT02EDTM":"2022-02-14 12:31:55","AP01SDTM":"2020-03-28 04:01:15","AP01EDTM":"2021-02-14 06:31:55","AP02SDTM":"2021-02-14 06:31:55","AP02EDTM":"2022-02-14 12:31:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":699,"ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5014,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.63719,"AVALU":"mg/L","BASE2":8.35819,"BASE":8.70012,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.279,"PCHG2":3.33809,"CHG":-0.06293,"PCHG":-0.72329,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-24 04:01:15","ADY":118,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-4","SUBJID":"id-4","SITEID":"RUS-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.7694,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-28 04:01:15","TRTEDTM":"2022-02-14 12:31:55","TRT01SDTM":"2020-03-28 04:01:15","TRT01EDTM":"2021-02-14 06:31:55","TRT02SDTM":"2021-02-14 06:31:55","TRT02EDTM":"2022-02-14 12:31:55","AP01SDTM":"2020-03-28 04:01:15","AP01EDTM":"2021-02-14 06:31:55","AP02SDTM":"2021-02-14 06:31:55","AP02EDTM":"2022-02-14 12:31:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":699,"ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6102,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.28987,"AVALU":"mg/L","BASE2":8.35819,"BASE":8.70012,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.06832,"PCHG2":-24.74606,"CHG":-2.41025,"PCHG":-27.70368,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-01-10 04:01:15","ADY":288,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-4","SUBJID":"id-4","SITEID":"RUS-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.7694,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-28 04:01:15","TRTEDTM":"2022-02-14 12:31:55","TRT01SDTM":"2020-03-28 04:01:15","TRT01EDTM":"2021-02-14 06:31:55","TRT02SDTM":"2021-02-14 06:31:55","TRT02EDTM":"2022-02-14 12:31:55","AP01SDTM":"2020-03-28 04:01:15","AP01EDTM":"2021-02-14 06:31:55","AP02SDTM":"2021-02-14 06:31:55","AP02EDTM":"2022-02-14 12:31:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":699,"ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4262,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.13007,"AVALU":"mg/L","BASE2":8.35819,"BASE":8.70012,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.22812,"PCHG2":-14.69363,"CHG":-1.57005,"PCHG":-18.04633,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-01-31 04:01:15","ADY":674,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-4","SUBJID":"id-4","SITEID":"RUS-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.7694,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-28 04:01:15","TRTEDTM":"2022-02-14 12:31:55","TRT01SDTM":"2020-03-28 04:01:15","TRT01EDTM":"2021-02-14 06:31:55","TRT02SDTM":"2021-02-14 06:31:55","TRT02EDTM":"2022-02-14 12:31:55","AP01SDTM":"2020-03-28 04:01:15","AP01EDTM":"2021-02-14 06:31:55","AP02SDTM":"2021-02-14 06:31:55","AP02EDTM":"2022-02-14 12:31:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":699,"ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7768,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.52469,"AVALU":"mg/L","BASE2":8.35819,"BASE":8.70012,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.8335,"PCHG2":-9.97226,"CHG":-1.17543,"PCHG":-13.51052,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-02-10 04:01:15","ADY":684,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-4","SUBJID":"id-4","SITEID":"RUS-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.7694,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-28 04:01:15","TRTEDTM":"2022-02-14 12:31:55","TRT01SDTM":"2020-03-28 04:01:15","TRT01EDTM":"2021-02-14 06:31:55","TRT02SDTM":"2021-02-14 06:31:55","TRT02EDTM":"2022-02-14 12:31:55","AP01SDTM":"2020-03-28 04:01:15","AP01EDTM":"2021-02-14 06:31:55","AP02SDTM":"2021-02-14 06:31:55","AP02EDTM":"2022-02-14 12:31:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":699,"ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6559,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93531,"AVALU":"g/L","BASE2":2.93531,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-19 04:01:15","ADY":22,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-4","SUBJID":"id-4","SITEID":"RUS-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.7694,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-28 04:01:15","TRTEDTM":"2022-02-14 12:31:55","TRT01SDTM":"2020-03-28 04:01:15","TRT01EDTM":"2021-02-14 06:31:55","TRT02SDTM":"2021-02-14 06:31:55","TRT02EDTM":"2022-02-14 12:31:55","AP01SDTM":"2020-03-28 04:01:15","AP01EDTM":"2021-02-14 06:31:55","AP02SDTM":"2021-02-14 06:31:55","AP02EDTM":"2022-02-14 12:31:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":699,"ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7398,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95922,"AVALU":"g/L","BASE2":2.93531,"BASE":2.95922,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.02391,"PCHG2":0.81458,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-24 04:01:15","ADY":27,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-4","SUBJID":"id-4","SITEID":"RUS-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.7694,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-28 04:01:15","TRTEDTM":"2022-02-14 12:31:55","TRT01SDTM":"2020-03-28 04:01:15","TRT01EDTM":"2021-02-14 06:31:55","TRT02SDTM":"2021-02-14 06:31:55","TRT02EDTM":"2022-02-14 12:31:55","AP01SDTM":"2020-03-28 04:01:15","AP01EDTM":"2021-02-14 06:31:55","AP02SDTM":"2021-02-14 06:31:55","AP02EDTM":"2022-02-14 12:31:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":699,"ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8111,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86435,"AVALU":"g/L","BASE2":2.93531,"BASE":2.95922,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07096,"PCHG2":-2.41743,"CHG":-0.09487,"PCHG":-3.20589,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-21 04:01:15","ADY":54,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-4","SUBJID":"id-4","SITEID":"RUS-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.7694,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-28 04:01:15","TRTEDTM":"2022-02-14 12:31:55","TRT01SDTM":"2020-03-28 04:01:15","TRT01EDTM":"2021-02-14 06:31:55","TRT02SDTM":"2021-02-14 06:31:55","TRT02EDTM":"2022-02-14 12:31:55","AP01SDTM":"2020-03-28 04:01:15","AP01EDTM":"2021-02-14 06:31:55","AP02SDTM":"2021-02-14 06:31:55","AP02EDTM":"2022-02-14 12:31:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":699,"ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2447,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95259,"AVALU":"g/L","BASE2":2.93531,"BASE":2.95922,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01728,"PCHG2":0.58884,"CHG":-0.00663,"PCHG":-0.22392,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-24 04:01:15","ADY":118,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-4","SUBJID":"id-4","SITEID":"RUS-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.7694,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-28 04:01:15","TRTEDTM":"2022-02-14 12:31:55","TRT01SDTM":"2020-03-28 04:01:15","TRT01EDTM":"2021-02-14 06:31:55","TRT02SDTM":"2021-02-14 06:31:55","TRT02EDTM":"2022-02-14 12:31:55","AP01SDTM":"2020-03-28 04:01:15","AP01EDTM":"2021-02-14 06:31:55","AP02SDTM":"2021-02-14 06:31:55","AP02EDTM":"2022-02-14 12:31:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":699,"ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":625,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03142,"AVALU":"g/L","BASE2":2.93531,"BASE":2.95922,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09611,"PCHG2":3.27432,"CHG":0.0722,"PCHG":2.43986,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-01-10 04:01:15","ADY":288,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-4","SUBJID":"id-4","SITEID":"RUS-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.7694,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-28 04:01:15","TRTEDTM":"2022-02-14 12:31:55","TRT01SDTM":"2020-03-28 04:01:15","TRT01EDTM":"2021-02-14 06:31:55","TRT02SDTM":"2021-02-14 06:31:55","TRT02EDTM":"2022-02-14 12:31:55","AP01SDTM":"2020-03-28 04:01:15","AP01EDTM":"2021-02-14 06:31:55","AP02SDTM":"2021-02-14 06:31:55","AP02EDTM":"2022-02-14 12:31:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":699,"ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1034,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95541,"AVALU":"g/L","BASE2":2.93531,"BASE":2.95922,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0201,"PCHG2":0.68475,"CHG":-0.00381,"PCHG":-0.12879,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-31 04:01:15","ADY":674,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-16-id-4","SUBJID":"id-4","SITEID":"RUS-16","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-16","INVNAM":"Dr. RUS-16 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":12.7694,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-25","TRTSDTM":"2020-03-28 04:01:15","TRTEDTM":"2022-02-14 12:31:55","TRT01SDTM":"2020-03-28 04:01:15","TRT01EDTM":"2021-02-14 06:31:55","TRT02SDTM":"2021-02-14 06:31:55","TRT02EDTM":"2022-02-14 12:31:55","AP01SDTM":"2020-03-28 04:01:15","AP01EDTM":"2021-02-14 06:31:55","AP02SDTM":"2021-02-14 06:31:55","AP02EDTM":"2022-02-14 12:31:55","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":689,"DCSREAS":"DEATH","DTHDT":"2022-02-26","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-26","DTHADY":699,"ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1139,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89193,"AVALU":"g/L","BASE2":2.93531,"BASE":2.95922,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04338,"PCHG2":-1.4778,"CHG":-0.06729,"PCHG":-2.27386,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-10 04:01:15","ADY":684,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-18-id-359","SUBJID":"id-359","SITEID":"RUS-18","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-18","INVNAM":"Dr. RUS-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.42016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-06-06","TRTSDTM":"2019-06-08 15:04:44","TRTEDTM":"2022-06-08 09:04:44","TRT01SDTM":"2019-06-08 15:04:44","TRT01EDTM":"2021-06-08 03:04:44","TRT02SDTM":"2021-06-08 03:04:44","TRT02EDTM":"2022-06-08 09:04:44","AP01SDTM":"2019-06-08 15:04:44","AP01EDTM":"2021-06-08 03:04:44","AP02SDTM":"2021-06-08 03:04:44","AP02EDTM":"2022-06-08 09:04:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-08","EOSDY":1096,"LSTALVDT":"2022-06-25","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2875,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.4112,"AVALU":"U/L","BASE2":21.4112,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-12 15:04:44","ADY":187,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-18-id-359","SUBJID":"id-359","SITEID":"RUS-18","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-18","INVNAM":"Dr. RUS-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.42016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-06-06","TRTSDTM":"2019-06-08 15:04:44","TRTEDTM":"2022-06-08 09:04:44","TRT01SDTM":"2019-06-08 15:04:44","TRT01EDTM":"2021-06-08 03:04:44","TRT02SDTM":"2021-06-08 03:04:44","TRT02EDTM":"2022-06-08 09:04:44","AP01SDTM":"2019-06-08 15:04:44","AP01EDTM":"2021-06-08 03:04:44","AP02SDTM":"2021-06-08 03:04:44","AP02EDTM":"2022-06-08 09:04:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-08","EOSDY":1096,"LSTALVDT":"2022-06-25","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3102,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":40.60216,"AVALU":"U/L","BASE2":21.4112,"BASE":40.60216,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":19.19096,"PCHG2":89.63049,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-14 15:04:44","ADY":189,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-18-id-359","SUBJID":"id-359","SITEID":"RUS-18","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-18","INVNAM":"Dr. RUS-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.42016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-06-06","TRTSDTM":"2019-06-08 15:04:44","TRTEDTM":"2022-06-08 09:04:44","TRT01SDTM":"2019-06-08 15:04:44","TRT01EDTM":"2021-06-08 03:04:44","TRT02SDTM":"2021-06-08 03:04:44","TRT02EDTM":"2022-06-08 09:04:44","AP01SDTM":"2019-06-08 15:04:44","AP01EDTM":"2021-06-08 03:04:44","AP02SDTM":"2021-06-08 03:04:44","AP02EDTM":"2022-06-08 09:04:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-08","EOSDY":1096,"LSTALVDT":"2022-06-25","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4027,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.38947,"AVALU":"U/L","BASE2":21.4112,"BASE":40.60216,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.02173,"PCHG2":-37.4651,"CHG":-27.21269,"PCHG":-67.02276,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-20 15:04:44","ADY":195,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-18-id-359","SUBJID":"id-359","SITEID":"RUS-18","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-18","INVNAM":"Dr. RUS-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.42016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-06-06","TRTSDTM":"2019-06-08 15:04:44","TRTEDTM":"2022-06-08 09:04:44","TRT01SDTM":"2019-06-08 15:04:44","TRT01EDTM":"2021-06-08 03:04:44","TRT02SDTM":"2021-06-08 03:04:44","TRT02EDTM":"2022-06-08 09:04:44","AP01SDTM":"2019-06-08 15:04:44","AP01EDTM":"2021-06-08 03:04:44","AP02SDTM":"2021-06-08 03:04:44","AP02EDTM":"2022-06-08 09:04:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-08","EOSDY":1096,"LSTALVDT":"2022-06-25","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2910,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.06253,"AVALU":"U/L","BASE2":21.4112,"BASE":40.60216,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.34866,"PCHG2":-62.34431,"CHG":-32.53962,"PCHG":-80.1426,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-07 15:04:44","ADY":365,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-18-id-359","SUBJID":"id-359","SITEID":"RUS-18","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-18","INVNAM":"Dr. RUS-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.42016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-06-06","TRTSDTM":"2019-06-08 15:04:44","TRTEDTM":"2022-06-08 09:04:44","TRT01SDTM":"2019-06-08 15:04:44","TRT01EDTM":"2021-06-08 03:04:44","TRT02SDTM":"2021-06-08 03:04:44","TRT02EDTM":"2022-06-08 09:04:44","AP01SDTM":"2019-06-08 15:04:44","AP01EDTM":"2021-06-08 03:04:44","AP02SDTM":"2021-06-08 03:04:44","AP02EDTM":"2022-06-08 09:04:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-08","EOSDY":1096,"LSTALVDT":"2022-06-25","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6971,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.95745,"AVALU":"U/L","BASE2":21.4112,"BASE":40.60216,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.45375,"PCHG2":-62.8351,"CHG":-32.64471,"PCHG":-80.40141,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-13 15:04:44","ADY":736,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-18-id-359","SUBJID":"id-359","SITEID":"RUS-18","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-18","INVNAM":"Dr. RUS-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.42016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-06-06","TRTSDTM":"2019-06-08 15:04:44","TRTEDTM":"2022-06-08 09:04:44","TRT01SDTM":"2019-06-08 15:04:44","TRT01EDTM":"2021-06-08 03:04:44","TRT02SDTM":"2021-06-08 03:04:44","TRT02EDTM":"2022-06-08 09:04:44","AP01SDTM":"2019-06-08 15:04:44","AP01EDTM":"2021-06-08 03:04:44","AP02SDTM":"2021-06-08 03:04:44","AP02EDTM":"2022-06-08 09:04:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-08","EOSDY":1096,"LSTALVDT":"2022-06-25","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4694,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.06504,"AVALU":"U/L","BASE2":21.4112,"BASE":40.60216,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.65384,"PCHG2":21.73556,"CHG":-14.53712,"PCHG":-35.80381,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-27 15:04:44","ADY":933,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-18-id-359","SUBJID":"id-359","SITEID":"RUS-18","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-18","INVNAM":"Dr. RUS-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.42016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-06-06","TRTSDTM":"2019-06-08 15:04:44","TRTEDTM":"2022-06-08 09:04:44","TRT01SDTM":"2019-06-08 15:04:44","TRT01EDTM":"2021-06-08 03:04:44","TRT02SDTM":"2021-06-08 03:04:44","TRT02EDTM":"2022-06-08 09:04:44","AP01SDTM":"2019-06-08 15:04:44","AP01EDTM":"2021-06-08 03:04:44","AP02SDTM":"2021-06-08 03:04:44","AP02EDTM":"2022-06-08 09:04:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-08","EOSDY":1096,"LSTALVDT":"2022-06-25","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7727,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.59758,"AVALU":"U/L","BASE2":21.4112,"BASE":40.60216,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.18638,"PCHG2":10.21138,"CHG":-17.00458,"PCHG":-41.88098,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-13 15:04:44","ADY":1070,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-18-id-359","SUBJID":"id-359","SITEID":"RUS-18","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-18","INVNAM":"Dr. RUS-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.42016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-06-06","TRTSDTM":"2019-06-08 15:04:44","TRTEDTM":"2022-06-08 09:04:44","TRT01SDTM":"2019-06-08 15:04:44","TRT01EDTM":"2021-06-08 03:04:44","TRT02SDTM":"2021-06-08 03:04:44","TRT02EDTM":"2022-06-08 09:04:44","AP01SDTM":"2019-06-08 15:04:44","AP01EDTM":"2021-06-08 03:04:44","AP02SDTM":"2021-06-08 03:04:44","AP02EDTM":"2022-06-08 09:04:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-08","EOSDY":1096,"LSTALVDT":"2022-06-25","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5002,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.66088,"AVALU":"mg/L","BASE2":8.66088,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-12 15:04:44","ADY":187,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-18-id-359","SUBJID":"id-359","SITEID":"RUS-18","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-18","INVNAM":"Dr. RUS-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.42016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-06-06","TRTSDTM":"2019-06-08 15:04:44","TRTEDTM":"2022-06-08 09:04:44","TRT01SDTM":"2019-06-08 15:04:44","TRT01EDTM":"2021-06-08 03:04:44","TRT02SDTM":"2021-06-08 03:04:44","TRT02EDTM":"2022-06-08 09:04:44","AP01SDTM":"2019-06-08 15:04:44","AP01EDTM":"2021-06-08 03:04:44","AP02SDTM":"2021-06-08 03:04:44","AP02EDTM":"2022-06-08 09:04:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-08","EOSDY":1096,"LSTALVDT":"2022-06-25","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3115,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.73246,"AVALU":"mg/L","BASE2":8.66088,"BASE":8.73246,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.07157,"PCHG2":0.8264,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-14 15:04:44","ADY":189,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-18-id-359","SUBJID":"id-359","SITEID":"RUS-18","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-18","INVNAM":"Dr. RUS-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.42016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-06-06","TRTSDTM":"2019-06-08 15:04:44","TRTEDTM":"2022-06-08 09:04:44","TRT01SDTM":"2019-06-08 15:04:44","TRT01EDTM":"2021-06-08 03:04:44","TRT02SDTM":"2021-06-08 03:04:44","TRT02EDTM":"2022-06-08 09:04:44","AP01SDTM":"2019-06-08 15:04:44","AP01EDTM":"2021-06-08 03:04:44","AP02SDTM":"2021-06-08 03:04:44","AP02EDTM":"2022-06-08 09:04:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-08","EOSDY":1096,"LSTALVDT":"2022-06-25","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5943,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.84558,"AVALU":"mg/L","BASE2":8.66088,"BASE":8.73246,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.8153,"PCHG2":-9.41358,"CHG":-0.88687,"PCHG":-10.15605,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2019-12-20 15:04:44","ADY":195,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-18-id-359","SUBJID":"id-359","SITEID":"RUS-18","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-18","INVNAM":"Dr. RUS-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.42016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-06-06","TRTSDTM":"2019-06-08 15:04:44","TRTEDTM":"2022-06-08 09:04:44","TRT01SDTM":"2019-06-08 15:04:44","TRT01EDTM":"2021-06-08 03:04:44","TRT02SDTM":"2021-06-08 03:04:44","TRT02EDTM":"2022-06-08 09:04:44","AP01SDTM":"2019-06-08 15:04:44","AP01EDTM":"2021-06-08 03:04:44","AP02SDTM":"2021-06-08 03:04:44","AP02EDTM":"2022-06-08 09:04:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-08","EOSDY":1096,"LSTALVDT":"2022-06-25","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6932,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.31827,"AVALU":"mg/L","BASE2":8.66088,"BASE":8.73246,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.65738,"PCHG2":7.59025,"CHG":0.58581,"PCHG":6.70841,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-07 15:04:44","ADY":365,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-18-id-359","SUBJID":"id-359","SITEID":"RUS-18","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-18","INVNAM":"Dr. RUS-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.42016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-06-06","TRTSDTM":"2019-06-08 15:04:44","TRTEDTM":"2022-06-08 09:04:44","TRT01SDTM":"2019-06-08 15:04:44","TRT01EDTM":"2021-06-08 03:04:44","TRT02SDTM":"2021-06-08 03:04:44","TRT02EDTM":"2022-06-08 09:04:44","AP01SDTM":"2019-06-08 15:04:44","AP01EDTM":"2021-06-08 03:04:44","AP02SDTM":"2021-06-08 03:04:44","AP02EDTM":"2022-06-08 09:04:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-08","EOSDY":1096,"LSTALVDT":"2022-06-25","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7653,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.73538,"AVALU":"mg/L","BASE2":8.66088,"BASE":8.73246,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0745,"PCHG2":0.86018,"CHG":0.00293,"PCHG":0.0335,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-13 15:04:44","ADY":736,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-18-id-359","SUBJID":"id-359","SITEID":"RUS-18","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-18","INVNAM":"Dr. RUS-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.42016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-06-06","TRTSDTM":"2019-06-08 15:04:44","TRTEDTM":"2022-06-08 09:04:44","TRT01SDTM":"2019-06-08 15:04:44","TRT01EDTM":"2021-06-08 03:04:44","TRT02SDTM":"2021-06-08 03:04:44","TRT02EDTM":"2022-06-08 09:04:44","AP01SDTM":"2019-06-08 15:04:44","AP01EDTM":"2021-06-08 03:04:44","AP02SDTM":"2021-06-08 03:04:44","AP02EDTM":"2022-06-08 09:04:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-08","EOSDY":1096,"LSTALVDT":"2022-06-25","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":857,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.78471,"AVALU":"mg/L","BASE2":8.66088,"BASE":8.73246,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12383,"PCHG2":1.42971,"CHG":0.05225,"PCHG":0.59836,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-27 15:04:44","ADY":933,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-18-id-359","SUBJID":"id-359","SITEID":"RUS-18","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-18","INVNAM":"Dr. RUS-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.42016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-06-06","TRTSDTM":"2019-06-08 15:04:44","TRTEDTM":"2022-06-08 09:04:44","TRT01SDTM":"2019-06-08 15:04:44","TRT01EDTM":"2021-06-08 03:04:44","TRT02SDTM":"2021-06-08 03:04:44","TRT02EDTM":"2022-06-08 09:04:44","AP01SDTM":"2019-06-08 15:04:44","AP01EDTM":"2021-06-08 03:04:44","AP02SDTM":"2021-06-08 03:04:44","AP02EDTM":"2022-06-08 09:04:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-08","EOSDY":1096,"LSTALVDT":"2022-06-25","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":689,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.503,"AVALU":"mg/L","BASE2":8.66088,"BASE":8.73246,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.84212,"PCHG2":21.26945,"CHG":1.77055,"PCHG":20.27549,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-05-13 15:04:44","ADY":1070,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-18-id-359","SUBJID":"id-359","SITEID":"RUS-18","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-18","INVNAM":"Dr. RUS-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.42016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-06-06","TRTSDTM":"2019-06-08 15:04:44","TRTEDTM":"2022-06-08 09:04:44","TRT01SDTM":"2019-06-08 15:04:44","TRT01EDTM":"2021-06-08 03:04:44","TRT02SDTM":"2021-06-08 03:04:44","TRT02EDTM":"2022-06-08 09:04:44","AP01SDTM":"2019-06-08 15:04:44","AP01EDTM":"2021-06-08 03:04:44","AP02SDTM":"2021-06-08 03:04:44","AP02EDTM":"2022-06-08 09:04:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-08","EOSDY":1096,"LSTALVDT":"2022-06-25","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91481,"AVALU":"g/L","BASE2":2.91481,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-12 15:04:44","ADY":187,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-18-id-359","SUBJID":"id-359","SITEID":"RUS-18","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-18","INVNAM":"Dr. RUS-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.42016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-06-06","TRTSDTM":"2019-06-08 15:04:44","TRTEDTM":"2022-06-08 09:04:44","TRT01SDTM":"2019-06-08 15:04:44","TRT01EDTM":"2021-06-08 03:04:44","TRT02SDTM":"2021-06-08 03:04:44","TRT02EDTM":"2022-06-08 09:04:44","AP01SDTM":"2019-06-08 15:04:44","AP01EDTM":"2021-06-08 03:04:44","AP02SDTM":"2021-06-08 03:04:44","AP02EDTM":"2022-06-08 09:04:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-08","EOSDY":1096,"LSTALVDT":"2022-06-25","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":999,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8514,"AVALU":"g/L","BASE2":2.91481,"BASE":2.8514,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.0634,"PCHG2":-2.17523,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-14 15:04:44","ADY":189,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-18-id-359","SUBJID":"id-359","SITEID":"RUS-18","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-18","INVNAM":"Dr. RUS-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.42016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-06-06","TRTSDTM":"2019-06-08 15:04:44","TRTEDTM":"2022-06-08 09:04:44","TRT01SDTM":"2019-06-08 15:04:44","TRT01EDTM":"2021-06-08 03:04:44","TRT02SDTM":"2021-06-08 03:04:44","TRT02EDTM":"2022-06-08 09:04:44","AP01SDTM":"2019-06-08 15:04:44","AP01EDTM":"2021-06-08 03:04:44","AP02SDTM":"2021-06-08 03:04:44","AP02EDTM":"2022-06-08 09:04:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-08","EOSDY":1096,"LSTALVDT":"2022-06-25","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8128,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98837,"AVALU":"g/L","BASE2":2.91481,"BASE":2.8514,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07356,"PCHG2":2.5236,"CHG":0.13696,"PCHG":4.80331,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-20 15:04:44","ADY":195,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-18-id-359","SUBJID":"id-359","SITEID":"RUS-18","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-18","INVNAM":"Dr. RUS-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.42016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-06-06","TRTSDTM":"2019-06-08 15:04:44","TRTEDTM":"2022-06-08 09:04:44","TRT01SDTM":"2019-06-08 15:04:44","TRT01EDTM":"2021-06-08 03:04:44","TRT02SDTM":"2021-06-08 03:04:44","TRT02EDTM":"2022-06-08 09:04:44","AP01SDTM":"2019-06-08 15:04:44","AP01EDTM":"2021-06-08 03:04:44","AP02SDTM":"2021-06-08 03:04:44","AP02EDTM":"2022-06-08 09:04:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-08","EOSDY":1096,"LSTALVDT":"2022-06-25","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4515,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80705,"AVALU":"g/L","BASE2":2.91481,"BASE":2.8514,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10775,"PCHG2":-3.69677,"CHG":-0.04435,"PCHG":-1.55538,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-07 15:04:44","ADY":365,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-18-id-359","SUBJID":"id-359","SITEID":"RUS-18","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-18","INVNAM":"Dr. RUS-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.42016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-06-06","TRTSDTM":"2019-06-08 15:04:44","TRTEDTM":"2022-06-08 09:04:44","TRT01SDTM":"2019-06-08 15:04:44","TRT01EDTM":"2021-06-08 03:04:44","TRT02SDTM":"2021-06-08 03:04:44","TRT02EDTM":"2022-06-08 09:04:44","AP01SDTM":"2019-06-08 15:04:44","AP01EDTM":"2021-06-08 03:04:44","AP02SDTM":"2021-06-08 03:04:44","AP02EDTM":"2022-06-08 09:04:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-08","EOSDY":1096,"LSTALVDT":"2022-06-25","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4254,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92183,"AVALU":"g/L","BASE2":2.91481,"BASE":2.8514,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00702,"PCHG2":0.24087,"CHG":0.07042,"PCHG":2.46982,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-13 15:04:44","ADY":736,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-18-id-359","SUBJID":"id-359","SITEID":"RUS-18","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-18","INVNAM":"Dr. RUS-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.42016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-06-06","TRTSDTM":"2019-06-08 15:04:44","TRTEDTM":"2022-06-08 09:04:44","TRT01SDTM":"2019-06-08 15:04:44","TRT01EDTM":"2021-06-08 03:04:44","TRT02SDTM":"2021-06-08 03:04:44","TRT02EDTM":"2022-06-08 09:04:44","AP01SDTM":"2019-06-08 15:04:44","AP01EDTM":"2021-06-08 03:04:44","AP02SDTM":"2021-06-08 03:04:44","AP02EDTM":"2022-06-08 09:04:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-08","EOSDY":1096,"LSTALVDT":"2022-06-25","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1614,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9831,"AVALU":"g/L","BASE2":2.91481,"BASE":2.8514,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06829,"PCHG2":2.34303,"CHG":0.1317,"PCHG":4.61873,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-27 15:04:44","ADY":933,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-18-id-359","SUBJID":"id-359","SITEID":"RUS-18","AGE":47,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-18","INVNAM":"Dr. RUS-18 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S1","BMRKR1":4.42016,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2019-06-06","TRTSDTM":"2019-06-08 15:04:44","TRTEDTM":"2022-06-08 09:04:44","TRT01SDTM":"2019-06-08 15:04:44","TRT01EDTM":"2021-06-08 03:04:44","TRT02SDTM":"2021-06-08 03:04:44","TRT02EDTM":"2022-06-08 09:04:44","AP01SDTM":"2019-06-08 15:04:44","AP01EDTM":"2021-06-08 03:04:44","AP02SDTM":"2021-06-08 03:04:44","AP02EDTM":"2022-06-08 09:04:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-08","EOSDY":1096,"LSTALVDT":"2022-06-25","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1665,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95436,"AVALU":"g/L","BASE2":2.91481,"BASE":2.8514,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03955,"PCHG2":1.35678,"CHG":0.10295,"PCHG":3.61055,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-13 15:04:44","ADY":1070,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-2-id-176","SUBJID":"id-176","SITEID":"RUS-2","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-2","INVNAM":"Dr. RUS-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65962,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-12","TRTSDTM":"2020-04-12 13:48:53","TRTEDTM":"2022-02-15 10:07:51","TRT01SDTM":"2020-04-12 13:48:53","TRT01EDTM":"2021-02-15 04:07:51","TRT02SDTM":"2021-02-15 04:07:51","TRT02EDTM":"2022-02-15 10:07:51","AP01SDTM":"2020-04-12 13:48:53","AP01EDTM":"2021-02-15 04:07:51","AP02SDTM":"2021-02-15 04:07:51","AP02EDTM":"2022-02-15 10:07:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":674,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":685,"ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1529,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.07311,"AVALU":"U/L","BASE2":25.07311,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-24 13:48:53","ADY":12,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-2-id-176","SUBJID":"id-176","SITEID":"RUS-2","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-2","INVNAM":"Dr. RUS-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65962,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-12","TRTSDTM":"2020-04-12 13:48:53","TRTEDTM":"2022-02-15 10:07:51","TRT01SDTM":"2020-04-12 13:48:53","TRT01EDTM":"2021-02-15 04:07:51","TRT02SDTM":"2021-02-15 04:07:51","TRT02EDTM":"2022-02-15 10:07:51","AP01SDTM":"2020-04-12 13:48:53","AP01EDTM":"2021-02-15 04:07:51","AP02SDTM":"2021-02-15 04:07:51","AP02EDTM":"2022-02-15 10:07:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":674,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":685,"ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1151,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.60377,"AVALU":"U/L","BASE2":25.07311,"BASE":19.60377,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-5.46934,"PCHG2":-21.81356,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-18 13:48:53","ADY":67,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-2-id-176","SUBJID":"id-176","SITEID":"RUS-2","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-2","INVNAM":"Dr. RUS-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65962,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-12","TRTSDTM":"2020-04-12 13:48:53","TRTEDTM":"2022-02-15 10:07:51","TRT01SDTM":"2020-04-12 13:48:53","TRT01EDTM":"2021-02-15 04:07:51","TRT02SDTM":"2021-02-15 04:07:51","TRT02EDTM":"2022-02-15 10:07:51","AP01SDTM":"2020-04-12 13:48:53","AP01EDTM":"2021-02-15 04:07:51","AP02SDTM":"2021-02-15 04:07:51","AP02EDTM":"2022-02-15 10:07:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":674,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":685,"ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6637,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.17308,"AVALU":"U/L","BASE2":25.07311,"BASE":19.60377,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.90003,"PCHG2":-47.46133,"CHG":-6.43069,"PCHG":-32.80335,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-23 13:48:53","ADY":255,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-2-id-176","SUBJID":"id-176","SITEID":"RUS-2","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-2","INVNAM":"Dr. RUS-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65962,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-12","TRTSDTM":"2020-04-12 13:48:53","TRTEDTM":"2022-02-15 10:07:51","TRT01SDTM":"2020-04-12 13:48:53","TRT01EDTM":"2021-02-15 04:07:51","TRT02SDTM":"2021-02-15 04:07:51","TRT02EDTM":"2022-02-15 10:07:51","AP01SDTM":"2020-04-12 13:48:53","AP01EDTM":"2021-02-15 04:07:51","AP02SDTM":"2021-02-15 04:07:51","AP02EDTM":"2022-02-15 10:07:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":674,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":685,"ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4960,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.10791,"AVALU":"U/L","BASE2":25.07311,"BASE":19.60377,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.96519,"PCHG2":-55.6979,"CHG":-8.49586,"PCHG":-43.33788,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-25 13:48:53","ADY":288,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-2-id-176","SUBJID":"id-176","SITEID":"RUS-2","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-2","INVNAM":"Dr. RUS-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65962,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-12","TRTSDTM":"2020-04-12 13:48:53","TRTEDTM":"2022-02-15 10:07:51","TRT01SDTM":"2020-04-12 13:48:53","TRT01EDTM":"2021-02-15 04:07:51","TRT02SDTM":"2021-02-15 04:07:51","TRT02EDTM":"2022-02-15 10:07:51","AP01SDTM":"2020-04-12 13:48:53","AP01EDTM":"2021-02-15 04:07:51","AP02SDTM":"2021-02-15 04:07:51","AP02EDTM":"2022-02-15 10:07:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":674,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":685,"ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":304,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.115,"AVALU":"U/L","BASE2":25.07311,"BASE":19.60377,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.9581,"PCHG2":-23.76293,"CHG":-0.48877,"PCHG":-2.49323,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-05 13:48:53","ADY":358,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-2-id-176","SUBJID":"id-176","SITEID":"RUS-2","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-2","INVNAM":"Dr. RUS-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65962,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-12","TRTSDTM":"2020-04-12 13:48:53","TRTEDTM":"2022-02-15 10:07:51","TRT01SDTM":"2020-04-12 13:48:53","TRT01EDTM":"2021-02-15 04:07:51","TRT02SDTM":"2021-02-15 04:07:51","TRT02EDTM":"2022-02-15 10:07:51","AP01SDTM":"2020-04-12 13:48:53","AP01EDTM":"2021-02-15 04:07:51","AP02SDTM":"2021-02-15 04:07:51","AP02EDTM":"2022-02-15 10:07:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":674,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":685,"ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2863,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.77482,"AVALU":"U/L","BASE2":25.07311,"BASE":19.60377,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.29829,"PCHG2":-57.02639,"CHG":-8.82895,"PCHG":-45.037,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-19 13:48:53","ADY":402,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-2-id-176","SUBJID":"id-176","SITEID":"RUS-2","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-2","INVNAM":"Dr. RUS-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65962,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-12","TRTSDTM":"2020-04-12 13:48:53","TRTEDTM":"2022-02-15 10:07:51","TRT01SDTM":"2020-04-12 13:48:53","TRT01EDTM":"2021-02-15 04:07:51","TRT02SDTM":"2021-02-15 04:07:51","TRT02EDTM":"2022-02-15 10:07:51","AP01SDTM":"2020-04-12 13:48:53","AP01EDTM":"2021-02-15 04:07:51","AP02SDTM":"2021-02-15 04:07:51","AP02EDTM":"2022-02-15 10:07:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":674,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":685,"ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5085,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.6703,"AVALU":"U/L","BASE2":25.07311,"BASE":19.60377,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-24.40281,"PCHG2":-97.32663,"CHG":-18.93347,"PCHG":-96.58077,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-09-16 13:48:53","ADY":522,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-2-id-176","SUBJID":"id-176","SITEID":"RUS-2","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-2","INVNAM":"Dr. RUS-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65962,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-12","TRTSDTM":"2020-04-12 13:48:53","TRTEDTM":"2022-02-15 10:07:51","TRT01SDTM":"2020-04-12 13:48:53","TRT01EDTM":"2021-02-15 04:07:51","TRT02SDTM":"2021-02-15 04:07:51","TRT02EDTM":"2022-02-15 10:07:51","AP01SDTM":"2020-04-12 13:48:53","AP01EDTM":"2021-02-15 04:07:51","AP02SDTM":"2021-02-15 04:07:51","AP02EDTM":"2022-02-15 10:07:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":674,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":685,"ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7013,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.32186,"AVALU":"mg/L","BASE2":9.32186,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-24 13:48:53","ADY":12,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-2-id-176","SUBJID":"id-176","SITEID":"RUS-2","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-2","INVNAM":"Dr. RUS-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65962,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-12","TRTSDTM":"2020-04-12 13:48:53","TRTEDTM":"2022-02-15 10:07:51","TRT01SDTM":"2020-04-12 13:48:53","TRT01EDTM":"2021-02-15 04:07:51","TRT02SDTM":"2021-02-15 04:07:51","TRT02EDTM":"2022-02-15 10:07:51","AP01SDTM":"2020-04-12 13:48:53","AP01EDTM":"2021-02-15 04:07:51","AP02SDTM":"2021-02-15 04:07:51","AP02EDTM":"2022-02-15 10:07:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":674,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":685,"ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4588,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.16959,"AVALU":"mg/L","BASE2":9.32186,"BASE":8.16959,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.15227,"PCHG2":-12.36096,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-18 13:48:53","ADY":67,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-2-id-176","SUBJID":"id-176","SITEID":"RUS-2","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-2","INVNAM":"Dr. RUS-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65962,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-12","TRTSDTM":"2020-04-12 13:48:53","TRTEDTM":"2022-02-15 10:07:51","TRT01SDTM":"2020-04-12 13:48:53","TRT01EDTM":"2021-02-15 04:07:51","TRT02SDTM":"2021-02-15 04:07:51","TRT02EDTM":"2022-02-15 10:07:51","AP01SDTM":"2020-04-12 13:48:53","AP01EDTM":"2021-02-15 04:07:51","AP02SDTM":"2021-02-15 04:07:51","AP02EDTM":"2022-02-15 10:07:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":674,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":685,"ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6796,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.28387,"AVALU":"mg/L","BASE2":9.32186,"BASE":8.16959,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03798,"PCHG2":-0.40747,"CHG":1.11429,"PCHG":13.63945,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-23 13:48:53","ADY":255,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-2-id-176","SUBJID":"id-176","SITEID":"RUS-2","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-2","INVNAM":"Dr. RUS-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65962,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-12","TRTSDTM":"2020-04-12 13:48:53","TRTEDTM":"2022-02-15 10:07:51","TRT01SDTM":"2020-04-12 13:48:53","TRT01EDTM":"2021-02-15 04:07:51","TRT02SDTM":"2021-02-15 04:07:51","TRT02EDTM":"2022-02-15 10:07:51","AP01SDTM":"2020-04-12 13:48:53","AP01EDTM":"2021-02-15 04:07:51","AP02SDTM":"2021-02-15 04:07:51","AP02EDTM":"2022-02-15 10:07:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":674,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":685,"ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5540,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.39131,"AVALU":"mg/L","BASE2":9.32186,"BASE":8.16959,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06945,"PCHG2":0.74507,"CHG":1.22172,"PCHG":14.95455,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-25 13:48:53","ADY":288,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-2-id-176","SUBJID":"id-176","SITEID":"RUS-2","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-2","INVNAM":"Dr. RUS-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65962,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-12","TRTSDTM":"2020-04-12 13:48:53","TRTEDTM":"2022-02-15 10:07:51","TRT01SDTM":"2020-04-12 13:48:53","TRT01EDTM":"2021-02-15 04:07:51","TRT02SDTM":"2021-02-15 04:07:51","TRT02EDTM":"2022-02-15 10:07:51","AP01SDTM":"2020-04-12 13:48:53","AP01EDTM":"2021-02-15 04:07:51","AP02SDTM":"2021-02-15 04:07:51","AP02EDTM":"2022-02-15 10:07:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":674,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":685,"ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2574,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.64709,"AVALU":"mg/L","BASE2":9.32186,"BASE":8.16959,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.67477,"PCHG2":-17.96602,"CHG":-0.5225,"PCHG":-6.39563,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-04-05 13:48:53","ADY":358,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-2-id-176","SUBJID":"id-176","SITEID":"RUS-2","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-2","INVNAM":"Dr. RUS-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65962,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-12","TRTSDTM":"2020-04-12 13:48:53","TRTEDTM":"2022-02-15 10:07:51","TRT01SDTM":"2020-04-12 13:48:53","TRT01EDTM":"2021-02-15 04:07:51","TRT02SDTM":"2021-02-15 04:07:51","TRT02EDTM":"2022-02-15 10:07:51","AP01SDTM":"2020-04-12 13:48:53","AP01EDTM":"2021-02-15 04:07:51","AP02SDTM":"2021-02-15 04:07:51","AP02EDTM":"2022-02-15 10:07:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":674,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":685,"ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1579,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.45027,"AVALU":"mg/L","BASE2":9.32186,"BASE":8.16959,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.87159,"PCHG2":-20.07741,"CHG":-0.71932,"PCHG":-8.80482,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-05-19 13:48:53","ADY":402,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-2-id-176","SUBJID":"id-176","SITEID":"RUS-2","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-2","INVNAM":"Dr. RUS-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65962,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-12","TRTSDTM":"2020-04-12 13:48:53","TRTEDTM":"2022-02-15 10:07:51","TRT01SDTM":"2020-04-12 13:48:53","TRT01EDTM":"2021-02-15 04:07:51","TRT02SDTM":"2021-02-15 04:07:51","TRT02EDTM":"2022-02-15 10:07:51","AP01SDTM":"2020-04-12 13:48:53","AP01EDTM":"2021-02-15 04:07:51","AP02SDTM":"2021-02-15 04:07:51","AP02EDTM":"2022-02-15 10:07:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":674,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":685,"ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2933,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.12683,"AVALU":"mg/L","BASE2":9.32186,"BASE":8.16959,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19503,"PCHG2":-2.09219,"CHG":0.95724,"PCHG":11.71711,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-16 13:48:53","ADY":522,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-2-id-176","SUBJID":"id-176","SITEID":"RUS-2","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-2","INVNAM":"Dr. RUS-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65962,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-12","TRTSDTM":"2020-04-12 13:48:53","TRTEDTM":"2022-02-15 10:07:51","TRT01SDTM":"2020-04-12 13:48:53","TRT01EDTM":"2021-02-15 04:07:51","TRT02SDTM":"2021-02-15 04:07:51","TRT02EDTM":"2022-02-15 10:07:51","AP01SDTM":"2020-04-12 13:48:53","AP01EDTM":"2021-02-15 04:07:51","AP02SDTM":"2021-02-15 04:07:51","AP02EDTM":"2022-02-15 10:07:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":674,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":685,"ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2634,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93866,"AVALU":"g/L","BASE2":2.93866,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-24 13:48:53","ADY":12,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-2-id-176","SUBJID":"id-176","SITEID":"RUS-2","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-2","INVNAM":"Dr. RUS-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65962,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-12","TRTSDTM":"2020-04-12 13:48:53","TRTEDTM":"2022-02-15 10:07:51","TRT01SDTM":"2020-04-12 13:48:53","TRT01EDTM":"2021-02-15 04:07:51","TRT02SDTM":"2021-02-15 04:07:51","TRT02EDTM":"2022-02-15 10:07:51","AP01SDTM":"2020-04-12 13:48:53","AP01EDTM":"2021-02-15 04:07:51","AP02SDTM":"2021-02-15 04:07:51","AP02EDTM":"2022-02-15 10:07:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":674,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":685,"ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4464,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9097,"AVALU":"g/L","BASE2":2.93866,"BASE":2.9097,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.02895,"PCHG2":-0.98521,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-18 13:48:53","ADY":67,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-2-id-176","SUBJID":"id-176","SITEID":"RUS-2","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-2","INVNAM":"Dr. RUS-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65962,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-12","TRTSDTM":"2020-04-12 13:48:53","TRTEDTM":"2022-02-15 10:07:51","TRT01SDTM":"2020-04-12 13:48:53","TRT01EDTM":"2021-02-15 04:07:51","TRT02SDTM":"2021-02-15 04:07:51","TRT02EDTM":"2022-02-15 10:07:51","AP01SDTM":"2020-04-12 13:48:53","AP01EDTM":"2021-02-15 04:07:51","AP02SDTM":"2021-02-15 04:07:51","AP02EDTM":"2022-02-15 10:07:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":674,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":685,"ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4898,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92573,"AVALU":"g/L","BASE2":2.93866,"BASE":2.9097,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01292,"PCHG2":-0.43974,"CHG":0.01603,"PCHG":0.5509,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-23 13:48:53","ADY":255,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-2-id-176","SUBJID":"id-176","SITEID":"RUS-2","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-2","INVNAM":"Dr. RUS-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65962,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-12","TRTSDTM":"2020-04-12 13:48:53","TRTEDTM":"2022-02-15 10:07:51","TRT01SDTM":"2020-04-12 13:48:53","TRT01EDTM":"2021-02-15 04:07:51","TRT02SDTM":"2021-02-15 04:07:51","TRT02EDTM":"2022-02-15 10:07:51","AP01SDTM":"2020-04-12 13:48:53","AP01EDTM":"2021-02-15 04:07:51","AP02SDTM":"2021-02-15 04:07:51","AP02EDTM":"2022-02-15 10:07:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":674,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":685,"ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":794,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01962,"AVALU":"g/L","BASE2":2.93866,"BASE":2.9097,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08097,"PCHG2":2.75522,"CHG":0.10992,"PCHG":3.77764,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-01-25 13:48:53","ADY":288,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-2-id-176","SUBJID":"id-176","SITEID":"RUS-2","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-2","INVNAM":"Dr. RUS-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65962,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-12","TRTSDTM":"2020-04-12 13:48:53","TRTEDTM":"2022-02-15 10:07:51","TRT01SDTM":"2020-04-12 13:48:53","TRT01EDTM":"2021-02-15 04:07:51","TRT02SDTM":"2021-02-15 04:07:51","TRT02EDTM":"2022-02-15 10:07:51","AP01SDTM":"2020-04-12 13:48:53","AP01EDTM":"2021-02-15 04:07:51","AP02SDTM":"2021-02-15 04:07:51","AP02EDTM":"2022-02-15 10:07:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":674,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":685,"ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7374,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85103,"AVALU":"g/L","BASE2":2.93866,"BASE":2.9097,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08762,"PCHG2":-2.98171,"CHG":-0.05867,"PCHG":-2.01636,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-05 13:48:53","ADY":358,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-2-id-176","SUBJID":"id-176","SITEID":"RUS-2","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-2","INVNAM":"Dr. RUS-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65962,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-12","TRTSDTM":"2020-04-12 13:48:53","TRTEDTM":"2022-02-15 10:07:51","TRT01SDTM":"2020-04-12 13:48:53","TRT01EDTM":"2021-02-15 04:07:51","TRT02SDTM":"2021-02-15 04:07:51","TRT02EDTM":"2022-02-15 10:07:51","AP01SDTM":"2020-04-12 13:48:53","AP01EDTM":"2021-02-15 04:07:51","AP02SDTM":"2021-02-15 04:07:51","AP02EDTM":"2022-02-15 10:07:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":674,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":685,"ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8050,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92692,"AVALU":"g/L","BASE2":2.93866,"BASE":2.9097,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01174,"PCHG2":-0.39942,"CHG":0.01721,"PCHG":0.59162,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-19 13:48:53","ADY":402,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-2-id-176","SUBJID":"id-176","SITEID":"RUS-2","AGE":42,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-2","INVNAM":"Dr. RUS-2 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":5.65962,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-12","TRTSDTM":"2020-04-12 13:48:53","TRTEDTM":"2022-02-15 10:07:51","TRT01SDTM":"2020-04-12 13:48:53","TRT01EDTM":"2021-02-15 04:07:51","TRT02SDTM":"2021-02-15 04:07:51","TRT02EDTM":"2022-02-15 10:07:51","AP01SDTM":"2020-04-12 13:48:53","AP01EDTM":"2021-02-15 04:07:51","AP02SDTM":"2021-02-15 04:07:51","AP02EDTM":"2022-02-15 10:07:51","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":674,"DCSREAS":"DEATH","DTHDT":"2022-02-27","DTHCAUS":"MISSING","DTHCAT":"OTHER","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-02-27","DTHADY":685,"ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5419,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89716,"AVALU":"g/L","BASE2":2.93866,"BASE":2.9097,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0415,"PCHG2":-1.41208,"CHG":-0.01254,"PCHG":-0.43111,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-16 13:48:53","ADY":522,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-3-id-378","SUBJID":"id-378","SITEID":"RUS-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-3","INVNAM":"Dr. RUS-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.80324,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-02-24","TRTSDTM":"2019-02-28 03:19:22","TRTEDTM":"2022-02-27 21:19:22","TRT01SDTM":"2019-02-28 03:19:22","TRT01EDTM":"2021-02-27 15:19:22","TRT02SDTM":"2021-02-27 15:19:22","TRT02EDTM":"2022-02-27 21:19:22","AP01SDTM":"2019-02-28 03:19:22","AP01EDTM":"2021-02-27 15:19:22","AP02SDTM":"2021-02-27 15:19:22","AP02EDTM":"2022-02-27 21:19:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-27","EOSDY":1096,"LSTALVDT":"2022-03-11","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6767,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.64371,"AVALU":"U/L","BASE2":9.64371,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-3","ADTM":"2019-06-13 03:19:22","ADY":105,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-3-id-378","SUBJID":"id-378","SITEID":"RUS-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-3","INVNAM":"Dr. RUS-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.80324,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-02-24","TRTSDTM":"2019-02-28 03:19:22","TRTEDTM":"2022-02-27 21:19:22","TRT01SDTM":"2019-02-28 03:19:22","TRT01EDTM":"2021-02-27 15:19:22","TRT02SDTM":"2021-02-27 15:19:22","TRT02EDTM":"2022-02-27 21:19:22","AP01SDTM":"2019-02-28 03:19:22","AP01EDTM":"2021-02-27 15:19:22","AP02SDTM":"2021-02-27 15:19:22","AP02EDTM":"2022-02-27 21:19:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-27","EOSDY":1096,"LSTALVDT":"2022-03-11","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2487,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.5683,"AVALU":"U/L","BASE2":9.64371,"BASE":0.5683,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-9.07542,"PCHG2":-94.10708,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2019-12-29 03:19:22","ADY":304,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-3-id-378","SUBJID":"id-378","SITEID":"RUS-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-3","INVNAM":"Dr. RUS-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.80324,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-02-24","TRTSDTM":"2019-02-28 03:19:22","TRTEDTM":"2022-02-27 21:19:22","TRT01SDTM":"2019-02-28 03:19:22","TRT01EDTM":"2021-02-27 15:19:22","TRT02SDTM":"2021-02-27 15:19:22","TRT02EDTM":"2022-02-27 21:19:22","AP01SDTM":"2019-02-28 03:19:22","AP01EDTM":"2021-02-27 15:19:22","AP02SDTM":"2021-02-27 15:19:22","AP02EDTM":"2022-02-27 21:19:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-27","EOSDY":1096,"LSTALVDT":"2022-03-11","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7992,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.02144,"AVALU":"U/L","BASE2":9.64371,"BASE":0.5683,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.37772,"PCHG2":97.2418,"CHG":18.45314,"PCHG":3247.09827,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2020-08-16 03:19:22","ADY":535,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-3-id-378","SUBJID":"id-378","SITEID":"RUS-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-3","INVNAM":"Dr. RUS-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.80324,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-02-24","TRTSDTM":"2019-02-28 03:19:22","TRTEDTM":"2022-02-27 21:19:22","TRT01SDTM":"2019-02-28 03:19:22","TRT01EDTM":"2021-02-27 15:19:22","TRT02SDTM":"2021-02-27 15:19:22","TRT02EDTM":"2022-02-27 21:19:22","AP01SDTM":"2019-02-28 03:19:22","AP01EDTM":"2021-02-27 15:19:22","AP02SDTM":"2021-02-27 15:19:22","AP02EDTM":"2022-02-27 21:19:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-27","EOSDY":1096,"LSTALVDT":"2022-03-11","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":448,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.09767,"AVALU":"U/L","BASE2":9.64371,"BASE":0.5683,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.54604,"PCHG2":-88.61777,"CHG":0.52937,"PCHG":93.15104,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-3","ADTM":"2020-09-01 03:19:22","ADY":551,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-3-id-378","SUBJID":"id-378","SITEID":"RUS-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-3","INVNAM":"Dr. RUS-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.80324,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-02-24","TRTSDTM":"2019-02-28 03:19:22","TRTEDTM":"2022-02-27 21:19:22","TRT01SDTM":"2019-02-28 03:19:22","TRT01EDTM":"2021-02-27 15:19:22","TRT02SDTM":"2021-02-27 15:19:22","TRT02EDTM":"2022-02-27 21:19:22","AP01SDTM":"2019-02-28 03:19:22","AP01EDTM":"2021-02-27 15:19:22","AP02SDTM":"2021-02-27 15:19:22","AP02EDTM":"2022-02-27 21:19:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-27","EOSDY":1096,"LSTALVDT":"2022-03-11","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7572,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.25854,"AVALU":"U/L","BASE2":9.64371,"BASE":0.5683,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.61483,"PCHG2":37.48379,"CHG":12.69025,"PCHG":2233.03365,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-07-06 03:19:22","ADY":859,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-3-id-378","SUBJID":"id-378","SITEID":"RUS-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-3","INVNAM":"Dr. RUS-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.80324,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-02-24","TRTSDTM":"2019-02-28 03:19:22","TRTEDTM":"2022-02-27 21:19:22","TRT01SDTM":"2019-02-28 03:19:22","TRT01EDTM":"2021-02-27 15:19:22","TRT02SDTM":"2021-02-27 15:19:22","TRT02EDTM":"2022-02-27 21:19:22","AP01SDTM":"2019-02-28 03:19:22","AP01EDTM":"2021-02-27 15:19:22","AP02SDTM":"2021-02-27 15:19:22","AP02EDTM":"2022-02-27 21:19:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-27","EOSDY":1096,"LSTALVDT":"2022-03-11","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1716,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.70335,"AVALU":"U/L","BASE2":9.64371,"BASE":0.5683,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.94036,"PCHG2":-61.59828,"CHG":3.13506,"PCHG":551.65872,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2021-07-23 03:19:22","ADY":876,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-3-id-378","SUBJID":"id-378","SITEID":"RUS-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-3","INVNAM":"Dr. RUS-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.80324,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-02-24","TRTSDTM":"2019-02-28 03:19:22","TRTEDTM":"2022-02-27 21:19:22","TRT01SDTM":"2019-02-28 03:19:22","TRT01EDTM":"2021-02-27 15:19:22","TRT02SDTM":"2021-02-27 15:19:22","TRT02EDTM":"2022-02-27 21:19:22","AP01SDTM":"2019-02-28 03:19:22","AP01EDTM":"2021-02-27 15:19:22","AP02SDTM":"2021-02-27 15:19:22","AP02EDTM":"2022-02-27 21:19:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-27","EOSDY":1096,"LSTALVDT":"2022-03-11","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5360,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.39436,"AVALU":"U/L","BASE2":9.64371,"BASE":0.5683,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.75064,"PCHG2":70.00046,"CHG":15.82606,"PCHG":2784.8259,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2022-01-15 03:19:22","ADY":1052,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-3-id-378","SUBJID":"id-378","SITEID":"RUS-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-3","INVNAM":"Dr. RUS-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.80324,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-02-24","TRTSDTM":"2019-02-28 03:19:22","TRTEDTM":"2022-02-27 21:19:22","TRT01SDTM":"2019-02-28 03:19:22","TRT01EDTM":"2021-02-27 15:19:22","TRT02SDTM":"2021-02-27 15:19:22","TRT02EDTM":"2022-02-27 21:19:22","AP01SDTM":"2019-02-28 03:19:22","AP01EDTM":"2021-02-27 15:19:22","AP02SDTM":"2021-02-27 15:19:22","AP02EDTM":"2022-02-27 21:19:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-27","EOSDY":1096,"LSTALVDT":"2022-03-11","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4091,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.22138,"AVALU":"mg/L","BASE2":10.22138,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"","ATOXGR":"3","BTOXGR":"-1","ADTM":"2019-06-13 03:19:22","ADY":105,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-3-id-378","SUBJID":"id-378","SITEID":"RUS-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-3","INVNAM":"Dr. RUS-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.80324,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-02-24","TRTSDTM":"2019-02-28 03:19:22","TRTEDTM":"2022-02-27 21:19:22","TRT01SDTM":"2019-02-28 03:19:22","TRT01EDTM":"2021-02-27 15:19:22","TRT02SDTM":"2021-02-27 15:19:22","TRT02EDTM":"2022-02-27 21:19:22","AP01SDTM":"2019-02-28 03:19:22","AP01EDTM":"2021-02-27 15:19:22","AP02SDTM":"2021-02-27 15:19:22","AP02EDTM":"2022-02-27 21:19:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-27","EOSDY":1096,"LSTALVDT":"2022-03-11","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3889,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.9646,"AVALU":"mg/L","BASE2":10.22138,"BASE":7.9646,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.25677,"PCHG2":-22.07896,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2019-12-29 03:19:22","ADY":304,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-3-id-378","SUBJID":"id-378","SITEID":"RUS-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-3","INVNAM":"Dr. RUS-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.80324,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-02-24","TRTSDTM":"2019-02-28 03:19:22","TRTEDTM":"2022-02-27 21:19:22","TRT01SDTM":"2019-02-28 03:19:22","TRT01EDTM":"2021-02-27 15:19:22","TRT02SDTM":"2021-02-27 15:19:22","TRT02EDTM":"2022-02-27 21:19:22","AP01SDTM":"2019-02-28 03:19:22","AP01EDTM":"2021-02-27 15:19:22","AP02SDTM":"2021-02-27 15:19:22","AP02EDTM":"2022-02-27 21:19:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-27","EOSDY":1096,"LSTALVDT":"2022-03-11","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3317,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.45163,"AVALU":"mg/L","BASE2":10.22138,"BASE":7.9646,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.76975,"PCHG2":-7.53081,"CHG":1.48702,"PCHG":18.67038,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-08-16 03:19:22","ADY":535,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-3-id-378","SUBJID":"id-378","SITEID":"RUS-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-3","INVNAM":"Dr. RUS-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.80324,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-02-24","TRTSDTM":"2019-02-28 03:19:22","TRTEDTM":"2022-02-27 21:19:22","TRT01SDTM":"2019-02-28 03:19:22","TRT01EDTM":"2021-02-27 15:19:22","TRT02SDTM":"2021-02-27 15:19:22","TRT02EDTM":"2022-02-27 21:19:22","AP01SDTM":"2019-02-28 03:19:22","AP01EDTM":"2021-02-27 15:19:22","AP02SDTM":"2021-02-27 15:19:22","AP02EDTM":"2022-02-27 21:19:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-27","EOSDY":1096,"LSTALVDT":"2022-03-11","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7422,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.99434,"AVALU":"mg/L","BASE2":10.22138,"BASE":7.9646,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.22704,"PCHG2":-12.00468,"CHG":1.02973,"PCHG":12.92884,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-09-01 03:19:22","ADY":551,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-3-id-378","SUBJID":"id-378","SITEID":"RUS-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-3","INVNAM":"Dr. RUS-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.80324,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-02-24","TRTSDTM":"2019-02-28 03:19:22","TRTEDTM":"2022-02-27 21:19:22","TRT01SDTM":"2019-02-28 03:19:22","TRT01EDTM":"2021-02-27 15:19:22","TRT02SDTM":"2021-02-27 15:19:22","TRT02EDTM":"2022-02-27 21:19:22","AP01SDTM":"2019-02-28 03:19:22","AP01EDTM":"2021-02-27 15:19:22","AP02SDTM":"2021-02-27 15:19:22","AP02EDTM":"2022-02-27 21:19:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-27","EOSDY":1096,"LSTALVDT":"2022-03-11","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6892,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.00324,"AVALU":"mg/L","BASE2":10.22138,"BASE":7.9646,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.21814,"PCHG2":-11.91754,"CHG":1.03864,"PCHG":13.04067,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-07-06 03:19:22","ADY":859,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-3-id-378","SUBJID":"id-378","SITEID":"RUS-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-3","INVNAM":"Dr. RUS-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.80324,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-02-24","TRTSDTM":"2019-02-28 03:19:22","TRTEDTM":"2022-02-27 21:19:22","TRT01SDTM":"2019-02-28 03:19:22","TRT01EDTM":"2021-02-27 15:19:22","TRT02SDTM":"2021-02-27 15:19:22","TRT02EDTM":"2022-02-27 21:19:22","AP01SDTM":"2019-02-28 03:19:22","AP01EDTM":"2021-02-27 15:19:22","AP02SDTM":"2021-02-27 15:19:22","AP02EDTM":"2022-02-27 21:19:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-27","EOSDY":1096,"LSTALVDT":"2022-03-11","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8015,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.10799,"AVALU":"mg/L","BASE2":10.22138,"BASE":7.9646,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.11339,"PCHG2":-20.6762,"CHG":0.14338,"PCHG":1.80024,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-07-23 03:19:22","ADY":876,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-3-id-378","SUBJID":"id-378","SITEID":"RUS-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-3","INVNAM":"Dr. RUS-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.80324,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-02-24","TRTSDTM":"2019-02-28 03:19:22","TRTEDTM":"2022-02-27 21:19:22","TRT01SDTM":"2019-02-28 03:19:22","TRT01EDTM":"2021-02-27 15:19:22","TRT02SDTM":"2021-02-27 15:19:22","TRT02EDTM":"2022-02-27 21:19:22","AP01SDTM":"2019-02-28 03:19:22","AP01EDTM":"2021-02-27 15:19:22","AP02SDTM":"2021-02-27 15:19:22","AP02EDTM":"2022-02-27 21:19:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-27","EOSDY":1096,"LSTALVDT":"2022-03-11","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5173,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.76572,"AVALU":"mg/L","BASE2":10.22138,"BASE":7.9646,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.45566,"PCHG2":-14.2413,"CHG":0.80112,"PCHG":10.05847,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2022-01-15 03:19:22","ADY":1052,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-3-id-378","SUBJID":"id-378","SITEID":"RUS-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-3","INVNAM":"Dr. RUS-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.80324,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-02-24","TRTSDTM":"2019-02-28 03:19:22","TRTEDTM":"2022-02-27 21:19:22","TRT01SDTM":"2019-02-28 03:19:22","TRT01EDTM":"2021-02-27 15:19:22","TRT02SDTM":"2021-02-27 15:19:22","TRT02EDTM":"2022-02-27 21:19:22","AP01SDTM":"2019-02-28 03:19:22","AP01EDTM":"2021-02-27 15:19:22","AP02SDTM":"2021-02-27 15:19:22","AP02EDTM":"2022-02-27 21:19:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-27","EOSDY":1096,"LSTALVDT":"2022-03-11","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5408,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85718,"AVALU":"g/L","BASE2":2.85718,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-06-13 03:19:22","ADY":105,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-3-id-378","SUBJID":"id-378","SITEID":"RUS-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-3","INVNAM":"Dr. RUS-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.80324,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-02-24","TRTSDTM":"2019-02-28 03:19:22","TRTEDTM":"2022-02-27 21:19:22","TRT01SDTM":"2019-02-28 03:19:22","TRT01EDTM":"2021-02-27 15:19:22","TRT02SDTM":"2021-02-27 15:19:22","TRT02EDTM":"2022-02-27 21:19:22","AP01SDTM":"2019-02-28 03:19:22","AP01EDTM":"2021-02-27 15:19:22","AP02SDTM":"2021-02-27 15:19:22","AP02EDTM":"2022-02-27 21:19:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-27","EOSDY":1096,"LSTALVDT":"2022-03-11","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2746,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89555,"AVALU":"g/L","BASE2":2.85718,"BASE":2.89555,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.03837,"PCHG2":1.34298,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-29 03:19:22","ADY":304,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-3-id-378","SUBJID":"id-378","SITEID":"RUS-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-3","INVNAM":"Dr. RUS-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.80324,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-02-24","TRTSDTM":"2019-02-28 03:19:22","TRTEDTM":"2022-02-27 21:19:22","TRT01SDTM":"2019-02-28 03:19:22","TRT01EDTM":"2021-02-27 15:19:22","TRT02SDTM":"2021-02-27 15:19:22","TRT02EDTM":"2022-02-27 21:19:22","AP01SDTM":"2019-02-28 03:19:22","AP01EDTM":"2021-02-27 15:19:22","AP02SDTM":"2021-02-27 15:19:22","AP02EDTM":"2022-02-27 21:19:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-27","EOSDY":1096,"LSTALVDT":"2022-03-11","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6157,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83578,"AVALU":"g/L","BASE2":2.85718,"BASE":2.89555,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0214,"PCHG2":-0.74885,"CHG":-0.05977,"PCHG":-2.06412,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-16 03:19:22","ADY":535,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-3-id-378","SUBJID":"id-378","SITEID":"RUS-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-3","INVNAM":"Dr. RUS-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.80324,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-02-24","TRTSDTM":"2019-02-28 03:19:22","TRTEDTM":"2022-02-27 21:19:22","TRT01SDTM":"2019-02-28 03:19:22","TRT01EDTM":"2021-02-27 15:19:22","TRT02SDTM":"2021-02-27 15:19:22","TRT02EDTM":"2022-02-27 21:19:22","AP01SDTM":"2019-02-28 03:19:22","AP01EDTM":"2021-02-27 15:19:22","AP02SDTM":"2021-02-27 15:19:22","AP02EDTM":"2022-02-27 21:19:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-27","EOSDY":1096,"LSTALVDT":"2022-03-11","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6030,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.08713,"AVALU":"g/L","BASE2":2.85718,"BASE":2.89555,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.22995,"PCHG2":8.04816,"CHG":0.19158,"PCHG":6.61632,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-09-01 03:19:22","ADY":551,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-3-id-378","SUBJID":"id-378","SITEID":"RUS-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-3","INVNAM":"Dr. RUS-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.80324,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-02-24","TRTSDTM":"2019-02-28 03:19:22","TRTEDTM":"2022-02-27 21:19:22","TRT01SDTM":"2019-02-28 03:19:22","TRT01EDTM":"2021-02-27 15:19:22","TRT02SDTM":"2021-02-27 15:19:22","TRT02EDTM":"2022-02-27 21:19:22","AP01SDTM":"2019-02-28 03:19:22","AP01EDTM":"2021-02-27 15:19:22","AP02SDTM":"2021-02-27 15:19:22","AP02EDTM":"2022-02-27 21:19:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-27","EOSDY":1096,"LSTALVDT":"2022-03-11","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7195,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8388,"AVALU":"g/L","BASE2":2.85718,"BASE":2.89555,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01838,"PCHG2":-0.64328,"CHG":-0.05675,"PCHG":-1.95995,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-06 03:19:22","ADY":859,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-3-id-378","SUBJID":"id-378","SITEID":"RUS-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-3","INVNAM":"Dr. RUS-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.80324,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-02-24","TRTSDTM":"2019-02-28 03:19:22","TRTEDTM":"2022-02-27 21:19:22","TRT01SDTM":"2019-02-28 03:19:22","TRT01EDTM":"2021-02-27 15:19:22","TRT02SDTM":"2021-02-27 15:19:22","TRT02EDTM":"2022-02-27 21:19:22","AP01SDTM":"2019-02-28 03:19:22","AP01EDTM":"2021-02-27 15:19:22","AP02SDTM":"2021-02-27 15:19:22","AP02EDTM":"2022-02-27 21:19:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-27","EOSDY":1096,"LSTALVDT":"2022-03-11","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6141,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82758,"AVALU":"g/L","BASE2":2.85718,"BASE":2.89555,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02959,"PCHG2":-1.0358,"CHG":-0.06797,"PCHG":-2.34727,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-23 03:19:22","ADY":876,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-3-id-378","SUBJID":"id-378","SITEID":"RUS-3","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-3","INVNAM":"Dr. RUS-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":2.80324,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-02-24","TRTSDTM":"2019-02-28 03:19:22","TRTEDTM":"2022-02-27 21:19:22","TRT01SDTM":"2019-02-28 03:19:22","TRT01EDTM":"2021-02-27 15:19:22","TRT02SDTM":"2021-02-27 15:19:22","TRT02EDTM":"2022-02-27 21:19:22","AP01SDTM":"2019-02-28 03:19:22","AP01EDTM":"2021-02-27 15:19:22","AP02SDTM":"2021-02-27 15:19:22","AP02EDTM":"2022-02-27 21:19:22","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-02-27","EOSDY":1096,"LSTALVDT":"2022-03-11","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":758,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00548,"AVALU":"g/L","BASE2":2.85718,"BASE":2.89555,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14831,"PCHG2":5.19066,"CHG":0.10994,"PCHG":3.79669,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-01-15 03:19:22","ADY":1052,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-150","SUBJID":"id-150","SITEID":"RUS-4","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.31455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-09 04:49:56","TRTEDTM":"2023-03-09 22:49:56","TRT01SDTM":"2020-03-09 04:49:56","TRT01EDTM":"2022-03-09 16:49:56","TRT02SDTM":"2022-03-09 16:49:56","TRT02EDTM":"2023-03-09 22:49:56","AP01SDTM":"2020-03-09 04:49:56","AP01EDTM":"2022-03-09 16:49:56","AP02SDTM":"2022-03-09 16:49:56","AP02EDTM":"2023-03-09 22:49:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7392,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.87838,"AVALU":"U/L","BASE2":27.87838,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-01 04:49:56","ADY":176,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-150","SUBJID":"id-150","SITEID":"RUS-4","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.31455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-09 04:49:56","TRTEDTM":"2023-03-09 22:49:56","TRT01SDTM":"2020-03-09 04:49:56","TRT01EDTM":"2022-03-09 16:49:56","TRT02SDTM":"2022-03-09 16:49:56","TRT02EDTM":"2023-03-09 22:49:56","AP01SDTM":"2020-03-09 04:49:56","AP01EDTM":"2022-03-09 16:49:56","AP02SDTM":"2022-03-09 16:49:56","AP02EDTM":"2023-03-09 22:49:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":106,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.48521,"AVALU":"U/L","BASE2":27.87838,"BASE":14.48521,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-13.39317,"PCHG2":-48.04142,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-27 04:49:56","ADY":324,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-150","SUBJID":"id-150","SITEID":"RUS-4","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.31455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-09 04:49:56","TRTEDTM":"2023-03-09 22:49:56","TRT01SDTM":"2020-03-09 04:49:56","TRT01EDTM":"2022-03-09 16:49:56","TRT02SDTM":"2022-03-09 16:49:56","TRT02EDTM":"2023-03-09 22:49:56","AP01SDTM":"2020-03-09 04:49:56","AP01EDTM":"2022-03-09 16:49:56","AP02SDTM":"2022-03-09 16:49:56","AP02EDTM":"2023-03-09 22:49:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7919,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.89396,"AVALU":"U/L","BASE2":27.87838,"BASE":14.48521,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-20.98443,"PCHG2":-75.27132,"CHG":-7.59126,"PCHG":-52.40693,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-06-15 04:49:56","ADY":463,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-150","SUBJID":"id-150","SITEID":"RUS-4","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.31455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-09 04:49:56","TRTEDTM":"2023-03-09 22:49:56","TRT01SDTM":"2020-03-09 04:49:56","TRT01EDTM":"2022-03-09 16:49:56","TRT02SDTM":"2022-03-09 16:49:56","TRT02EDTM":"2023-03-09 22:49:56","AP01SDTM":"2020-03-09 04:49:56","AP01EDTM":"2022-03-09 16:49:56","AP02SDTM":"2022-03-09 16:49:56","AP02EDTM":"2023-03-09 22:49:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5879,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.74015,"AVALU":"U/L","BASE2":27.87838,"BASE":14.48521,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.13823,"PCHG2":-7.66986,"CHG":11.25494,"PCHG":77.69951,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-12 04:49:56","ADY":674,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-150","SUBJID":"id-150","SITEID":"RUS-4","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.31455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-09 04:49:56","TRTEDTM":"2023-03-09 22:49:56","TRT01SDTM":"2020-03-09 04:49:56","TRT01EDTM":"2022-03-09 16:49:56","TRT02SDTM":"2022-03-09 16:49:56","TRT02EDTM":"2023-03-09 22:49:56","AP01SDTM":"2020-03-09 04:49:56","AP01EDTM":"2022-03-09 16:49:56","AP02SDTM":"2022-03-09 16:49:56","AP02EDTM":"2023-03-09 22:49:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1395,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.9914,"AVALU":"U/L","BASE2":27.87838,"BASE":14.48521,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.11302,"PCHG2":11.16641,"CHG":16.50619,"PCHG":113.95199,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-29 04:49:56","ADY":750,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-150","SUBJID":"id-150","SITEID":"RUS-4","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.31455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-09 04:49:56","TRTEDTM":"2023-03-09 22:49:56","TRT01SDTM":"2020-03-09 04:49:56","TRT01EDTM":"2022-03-09 16:49:56","TRT02SDTM":"2022-03-09 16:49:56","TRT02EDTM":"2023-03-09 22:49:56","AP01SDTM":"2020-03-09 04:49:56","AP01EDTM":"2022-03-09 16:49:56","AP02SDTM":"2022-03-09 16:49:56","AP02EDTM":"2023-03-09 22:49:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5030,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.99531,"AVALU":"U/L","BASE2":27.87838,"BASE":14.48521,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-23.88307,"PCHG2":-85.66879,"CHG":-10.4899,"PCHG":-72.418,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2022-06-09 04:49:56","ADY":822,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-150","SUBJID":"id-150","SITEID":"RUS-4","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.31455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-09 04:49:56","TRTEDTM":"2023-03-09 22:49:56","TRT01SDTM":"2020-03-09 04:49:56","TRT01EDTM":"2022-03-09 16:49:56","TRT02SDTM":"2022-03-09 16:49:56","TRT02EDTM":"2023-03-09 22:49:56","AP01SDTM":"2020-03-09 04:49:56","AP01EDTM":"2022-03-09 16:49:56","AP02SDTM":"2022-03-09 16:49:56","AP02EDTM":"2023-03-09 22:49:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":191,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.13644,"AVALU":"U/L","BASE2":27.87838,"BASE":14.48521,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-25.74194,"PCHG2":-92.33655,"CHG":-12.34877,"PCHG":-85.25086,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-10-27 04:49:56","ADY":962,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-150","SUBJID":"id-150","SITEID":"RUS-4","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.31455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-09 04:49:56","TRTEDTM":"2023-03-09 22:49:56","TRT01SDTM":"2020-03-09 04:49:56","TRT01EDTM":"2022-03-09 16:49:56","TRT02SDTM":"2022-03-09 16:49:56","TRT02EDTM":"2023-03-09 22:49:56","AP01SDTM":"2020-03-09 04:49:56","AP01EDTM":"2022-03-09 16:49:56","AP02SDTM":"2022-03-09 16:49:56","AP02EDTM":"2023-03-09 22:49:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5884,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.20511,"AVALU":"mg/L","BASE2":10.20511,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-09-01 04:49:56","ADY":176,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-150","SUBJID":"id-150","SITEID":"RUS-4","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.31455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-09 04:49:56","TRTEDTM":"2023-03-09 22:49:56","TRT01SDTM":"2020-03-09 04:49:56","TRT01EDTM":"2022-03-09 16:49:56","TRT02SDTM":"2022-03-09 16:49:56","TRT02EDTM":"2023-03-09 22:49:56","AP01SDTM":"2020-03-09 04:49:56","AP01EDTM":"2022-03-09 16:49:56","AP02SDTM":"2022-03-09 16:49:56","AP02EDTM":"2023-03-09 22:49:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":388,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.7138,"AVALU":"mg/L","BASE2":10.20511,"BASE":8.7138,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.49131,"PCHG2":-14.61338,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-27 04:49:56","ADY":324,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-150","SUBJID":"id-150","SITEID":"RUS-4","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.31455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-09 04:49:56","TRTEDTM":"2023-03-09 22:49:56","TRT01SDTM":"2020-03-09 04:49:56","TRT01EDTM":"2022-03-09 16:49:56","TRT02SDTM":"2022-03-09 16:49:56","TRT02EDTM":"2023-03-09 22:49:56","AP01SDTM":"2020-03-09 04:49:56","AP01EDTM":"2022-03-09 16:49:56","AP02SDTM":"2022-03-09 16:49:56","AP02EDTM":"2023-03-09 22:49:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4837,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.18632,"AVALU":"mg/L","BASE2":10.20511,"BASE":8.7138,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.01879,"PCHG2":-9.98312,"CHG":0.47252,"PCHG":5.42271,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-15 04:49:56","ADY":463,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-150","SUBJID":"id-150","SITEID":"RUS-4","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.31455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-09 04:49:56","TRTEDTM":"2023-03-09 22:49:56","TRT01SDTM":"2020-03-09 04:49:56","TRT01EDTM":"2022-03-09 16:49:56","TRT02SDTM":"2022-03-09 16:49:56","TRT02EDTM":"2023-03-09 22:49:56","AP01SDTM":"2020-03-09 04:49:56","AP01EDTM":"2022-03-09 16:49:56","AP02SDTM":"2022-03-09 16:49:56","AP02EDTM":"2023-03-09 22:49:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1919,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.82683,"AVALU":"mg/L","BASE2":10.20511,"BASE":8.7138,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.37828,"PCHG2":-23.30478,"CHG":-0.88697,"PCHG":-10.17887,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2022-01-12 04:49:56","ADY":674,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-150","SUBJID":"id-150","SITEID":"RUS-4","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.31455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-09 04:49:56","TRTEDTM":"2023-03-09 22:49:56","TRT01SDTM":"2020-03-09 04:49:56","TRT01EDTM":"2022-03-09 16:49:56","TRT02SDTM":"2022-03-09 16:49:56","TRT02EDTM":"2023-03-09 22:49:56","AP01SDTM":"2020-03-09 04:49:56","AP01EDTM":"2022-03-09 16:49:56","AP02SDTM":"2022-03-09 16:49:56","AP02EDTM":"2023-03-09 22:49:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":143,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.01913,"AVALU":"mg/L","BASE2":10.20511,"BASE":8.7138,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.18598,"PCHG2":-11.62143,"CHG":0.30533,"PCHG":3.504,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-29 04:49:56","ADY":750,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-150","SUBJID":"id-150","SITEID":"RUS-4","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.31455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-09 04:49:56","TRTEDTM":"2023-03-09 22:49:56","TRT01SDTM":"2020-03-09 04:49:56","TRT01EDTM":"2022-03-09 16:49:56","TRT02SDTM":"2022-03-09 16:49:56","TRT02EDTM":"2023-03-09 22:49:56","AP01SDTM":"2020-03-09 04:49:56","AP01EDTM":"2022-03-09 16:49:56","AP02SDTM":"2022-03-09 16:49:56","AP02EDTM":"2023-03-09 22:49:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1478,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.13949,"AVALU":"mg/L","BASE2":10.20511,"BASE":8.7138,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.06563,"PCHG2":-20.24109,"CHG":-0.57431,"PCHG":-6.59085,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-09 04:49:56","ADY":822,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-150","SUBJID":"id-150","SITEID":"RUS-4","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.31455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-09 04:49:56","TRTEDTM":"2023-03-09 22:49:56","TRT01SDTM":"2020-03-09 04:49:56","TRT01EDTM":"2022-03-09 16:49:56","TRT02SDTM":"2022-03-09 16:49:56","TRT02EDTM":"2023-03-09 22:49:56","AP01SDTM":"2020-03-09 04:49:56","AP01EDTM":"2022-03-09 16:49:56","AP02SDTM":"2022-03-09 16:49:56","AP02EDTM":"2023-03-09 22:49:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1240,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.81398,"AVALU":"mg/L","BASE2":10.20511,"BASE":8.7138,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.39113,"PCHG2":-13.6317,"CHG":0.10018,"PCHG":1.14969,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-27 04:49:56","ADY":962,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-150","SUBJID":"id-150","SITEID":"RUS-4","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.31455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-09 04:49:56","TRTEDTM":"2023-03-09 22:49:56","TRT01SDTM":"2020-03-09 04:49:56","TRT01EDTM":"2022-03-09 16:49:56","TRT02SDTM":"2022-03-09 16:49:56","TRT02EDTM":"2023-03-09 22:49:56","AP01SDTM":"2020-03-09 04:49:56","AP01EDTM":"2022-03-09 16:49:56","AP02SDTM":"2022-03-09 16:49:56","AP02EDTM":"2023-03-09 22:49:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3245,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84355,"AVALU":"g/L","BASE2":2.84355,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-01 04:49:56","ADY":176,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-150","SUBJID":"id-150","SITEID":"RUS-4","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.31455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-09 04:49:56","TRTEDTM":"2023-03-09 22:49:56","TRT01SDTM":"2020-03-09 04:49:56","TRT01EDTM":"2022-03-09 16:49:56","TRT02SDTM":"2022-03-09 16:49:56","TRT02EDTM":"2023-03-09 22:49:56","AP01SDTM":"2020-03-09 04:49:56","AP01EDTM":"2022-03-09 16:49:56","AP02SDTM":"2022-03-09 16:49:56","AP02EDTM":"2023-03-09 22:49:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7114,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83027,"AVALU":"g/L","BASE2":2.84355,"BASE":2.83027,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.01328,"PCHG2":-0.46711,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-27 04:49:56","ADY":324,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-150","SUBJID":"id-150","SITEID":"RUS-4","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.31455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-09 04:49:56","TRTEDTM":"2023-03-09 22:49:56","TRT01SDTM":"2020-03-09 04:49:56","TRT01EDTM":"2022-03-09 16:49:56","TRT02SDTM":"2022-03-09 16:49:56","TRT02EDTM":"2023-03-09 22:49:56","AP01SDTM":"2020-03-09 04:49:56","AP01EDTM":"2022-03-09 16:49:56","AP02SDTM":"2022-03-09 16:49:56","AP02EDTM":"2023-03-09 22:49:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5564,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93028,"AVALU":"g/L","BASE2":2.84355,"BASE":2.83027,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08672,"PCHG2":3.04986,"CHG":0.10001,"PCHG":3.53347,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-15 04:49:56","ADY":463,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-150","SUBJID":"id-150","SITEID":"RUS-4","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.31455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-09 04:49:56","TRTEDTM":"2023-03-09 22:49:56","TRT01SDTM":"2020-03-09 04:49:56","TRT01EDTM":"2022-03-09 16:49:56","TRT02SDTM":"2022-03-09 16:49:56","TRT02EDTM":"2023-03-09 22:49:56","AP01SDTM":"2020-03-09 04:49:56","AP01EDTM":"2022-03-09 16:49:56","AP02SDTM":"2022-03-09 16:49:56","AP02EDTM":"2023-03-09 22:49:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4469,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91377,"AVALU":"g/L","BASE2":2.84355,"BASE":2.83027,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07022,"PCHG2":2.46936,"CHG":0.0835,"PCHG":2.95025,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-12 04:49:56","ADY":674,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-150","SUBJID":"id-150","SITEID":"RUS-4","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.31455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-09 04:49:56","TRTEDTM":"2023-03-09 22:49:56","TRT01SDTM":"2020-03-09 04:49:56","TRT01EDTM":"2022-03-09 16:49:56","TRT02SDTM":"2022-03-09 16:49:56","TRT02EDTM":"2023-03-09 22:49:56","AP01SDTM":"2020-03-09 04:49:56","AP01EDTM":"2022-03-09 16:49:56","AP02SDTM":"2022-03-09 16:49:56","AP02EDTM":"2023-03-09 22:49:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":291,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90424,"AVALU":"g/L","BASE2":2.84355,"BASE":2.83027,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06068,"PCHG2":2.13403,"CHG":0.07396,"PCHG":2.61334,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-29 04:49:56","ADY":750,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-150","SUBJID":"id-150","SITEID":"RUS-4","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.31455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-09 04:49:56","TRTEDTM":"2023-03-09 22:49:56","TRT01SDTM":"2020-03-09 04:49:56","TRT01EDTM":"2022-03-09 16:49:56","TRT02SDTM":"2022-03-09 16:49:56","TRT02EDTM":"2023-03-09 22:49:56","AP01SDTM":"2020-03-09 04:49:56","AP01EDTM":"2022-03-09 16:49:56","AP02SDTM":"2022-03-09 16:49:56","AP02EDTM":"2023-03-09 22:49:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7562,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.12257,"AVALU":"g/L","BASE2":2.84355,"BASE":2.83027,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.27901,"PCHG2":9.81216,"CHG":0.2923,"PCHG":10.32751,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2022-06-09 04:49:56","ADY":822,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-150","SUBJID":"id-150","SITEID":"RUS-4","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S1","BMRKR1":3.31455,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-09 04:49:56","TRTEDTM":"2023-03-09 22:49:56","TRT01SDTM":"2020-03-09 04:49:56","TRT01EDTM":"2022-03-09 16:49:56","TRT02SDTM":"2022-03-09 16:49:56","TRT02EDTM":"2023-03-09 22:49:56","AP01SDTM":"2020-03-09 04:49:56","AP01EDTM":"2022-03-09 16:49:56","AP02SDTM":"2022-03-09 16:49:56","AP02EDTM":"2023-03-09 22:49:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-09","EOSDY":1096,"LSTALVDT":"2023-03-31","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":471,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.66962,"AVALU":"g/L","BASE2":2.84355,"BASE":2.83027,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17393,"PCHG2":-6.11673,"CHG":-0.16065,"PCHG":-5.67614,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-27 04:49:56","ADY":962,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-180","SUBJID":"id-180","SITEID":"RUS-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.62272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-17","TRTSDTM":"2019-06-21 02:08:16","TRTEDTM":"2022-06-20 20:08:16","TRT01SDTM":"2019-06-21 02:08:16","TRT01EDTM":"2021-06-20 14:08:16","TRT02SDTM":"2021-06-20 14:08:16","TRT02EDTM":"2022-06-20 20:08:16","AP01SDTM":"2019-06-21 02:08:16","AP01EDTM":"2021-06-20 14:08:16","AP02SDTM":"2021-06-20 14:08:16","AP02EDTM":"2022-06-20 20:08:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-20","EOSDY":1096,"LSTALVDT":"2022-07-05","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7593,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.32779,"AVALU":"U/L","BASE2":14.32779,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-14 02:08:16","ADY":23,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-180","SUBJID":"id-180","SITEID":"RUS-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.62272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-17","TRTSDTM":"2019-06-21 02:08:16","TRTEDTM":"2022-06-20 20:08:16","TRT01SDTM":"2019-06-21 02:08:16","TRT01EDTM":"2021-06-20 14:08:16","TRT02SDTM":"2021-06-20 14:08:16","TRT02EDTM":"2022-06-20 20:08:16","AP01SDTM":"2019-06-21 02:08:16","AP01EDTM":"2021-06-20 14:08:16","AP02SDTM":"2021-06-20 14:08:16","AP02EDTM":"2022-06-20 20:08:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-20","EOSDY":1096,"LSTALVDT":"2022-07-05","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5849,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.07456,"AVALU":"U/L","BASE2":14.32779,"BASE":24.07456,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":9.74677,"PCHG2":68.02705,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-15 02:08:16","ADY":116,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-180","SUBJID":"id-180","SITEID":"RUS-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.62272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-17","TRTSDTM":"2019-06-21 02:08:16","TRTEDTM":"2022-06-20 20:08:16","TRT01SDTM":"2019-06-21 02:08:16","TRT01EDTM":"2021-06-20 14:08:16","TRT02SDTM":"2021-06-20 14:08:16","TRT02EDTM":"2022-06-20 20:08:16","AP01SDTM":"2019-06-21 02:08:16","AP01EDTM":"2021-06-20 14:08:16","AP02SDTM":"2021-06-20 14:08:16","AP02EDTM":"2022-06-20 20:08:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-20","EOSDY":1096,"LSTALVDT":"2022-07-05","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1177,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.61014,"AVALU":"U/L","BASE2":14.32779,"BASE":24.07456,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.71765,"PCHG2":-11.98824,"CHG":-11.46442,"PCHG":-47.62048,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-15 02:08:16","ADY":329,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-180","SUBJID":"id-180","SITEID":"RUS-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.62272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-17","TRTSDTM":"2019-06-21 02:08:16","TRTEDTM":"2022-06-20 20:08:16","TRT01SDTM":"2019-06-21 02:08:16","TRT01EDTM":"2021-06-20 14:08:16","TRT02SDTM":"2021-06-20 14:08:16","TRT02EDTM":"2022-06-20 20:08:16","AP01SDTM":"2019-06-21 02:08:16","AP01EDTM":"2021-06-20 14:08:16","AP02SDTM":"2021-06-20 14:08:16","AP02EDTM":"2022-06-20 20:08:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-20","EOSDY":1096,"LSTALVDT":"2022-07-05","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3175,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.28458,"AVALU":"U/L","BASE2":14.32779,"BASE":24.07456,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.95679,"PCHG2":48.55457,"CHG":-2.78998,"PCHG":-11.5889,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-30 02:08:16","ADY":558,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-180","SUBJID":"id-180","SITEID":"RUS-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.62272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-17","TRTSDTM":"2019-06-21 02:08:16","TRTEDTM":"2022-06-20 20:08:16","TRT01SDTM":"2019-06-21 02:08:16","TRT01EDTM":"2021-06-20 14:08:16","TRT02SDTM":"2021-06-20 14:08:16","TRT02EDTM":"2022-06-20 20:08:16","AP01SDTM":"2019-06-21 02:08:16","AP01EDTM":"2021-06-20 14:08:16","AP02SDTM":"2021-06-20 14:08:16","AP02EDTM":"2022-06-20 20:08:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-20","EOSDY":1096,"LSTALVDT":"2022-07-05","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2915,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.03665,"AVALU":"U/L","BASE2":14.32779,"BASE":24.07456,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.70887,"PCHG2":81.72141,"CHG":1.9621,"PCHG":8.15009,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-13 02:08:16","ADY":603,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-180","SUBJID":"id-180","SITEID":"RUS-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.62272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-17","TRTSDTM":"2019-06-21 02:08:16","TRTEDTM":"2022-06-20 20:08:16","TRT01SDTM":"2019-06-21 02:08:16","TRT01EDTM":"2021-06-20 14:08:16","TRT02SDTM":"2021-06-20 14:08:16","TRT02EDTM":"2022-06-20 20:08:16","AP01SDTM":"2019-06-21 02:08:16","AP01EDTM":"2021-06-20 14:08:16","AP02SDTM":"2021-06-20 14:08:16","AP02EDTM":"2022-06-20 20:08:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-20","EOSDY":1096,"LSTALVDT":"2022-07-05","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5500,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.98916,"AVALU":"U/L","BASE2":14.32779,"BASE":24.07456,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":17.66137,"PCHG2":123.26659,"CHG":7.9146,"PCHG":32.87538,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-16 02:08:16","ADY":1030,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-180","SUBJID":"id-180","SITEID":"RUS-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.62272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-17","TRTSDTM":"2019-06-21 02:08:16","TRTEDTM":"2022-06-20 20:08:16","TRT01SDTM":"2019-06-21 02:08:16","TRT01EDTM":"2021-06-20 14:08:16","TRT02SDTM":"2021-06-20 14:08:16","TRT02EDTM":"2022-06-20 20:08:16","AP01SDTM":"2019-06-21 02:08:16","AP01EDTM":"2021-06-20 14:08:16","AP02SDTM":"2021-06-20 14:08:16","AP02EDTM":"2022-06-20 20:08:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-20","EOSDY":1096,"LSTALVDT":"2022-07-05","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5919,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.32351,"AVALU":"U/L","BASE2":14.32779,"BASE":24.07456,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.00428,"PCHG2":-34.92707,"CHG":-14.75105,"PCHG":-61.27235,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-22 02:08:16","ADY":1036,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-180","SUBJID":"id-180","SITEID":"RUS-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.62272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-17","TRTSDTM":"2019-06-21 02:08:16","TRTEDTM":"2022-06-20 20:08:16","TRT01SDTM":"2019-06-21 02:08:16","TRT01EDTM":"2021-06-20 14:08:16","TRT02SDTM":"2021-06-20 14:08:16","TRT02EDTM":"2022-06-20 20:08:16","AP01SDTM":"2019-06-21 02:08:16","AP01EDTM":"2021-06-20 14:08:16","AP02SDTM":"2021-06-20 14:08:16","AP02EDTM":"2022-06-20 20:08:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-20","EOSDY":1096,"LSTALVDT":"2022-07-05","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1899,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.37558,"AVALU":"mg/L","BASE2":10.37558,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"3","BTOXGR":"0","ADTM":"2019-07-14 02:08:16","ADY":23,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-180","SUBJID":"id-180","SITEID":"RUS-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.62272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-17","TRTSDTM":"2019-06-21 02:08:16","TRTEDTM":"2022-06-20 20:08:16","TRT01SDTM":"2019-06-21 02:08:16","TRT01EDTM":"2021-06-20 14:08:16","TRT02SDTM":"2021-06-20 14:08:16","TRT02EDTM":"2022-06-20 20:08:16","AP01SDTM":"2019-06-21 02:08:16","AP01EDTM":"2021-06-20 14:08:16","AP02SDTM":"2021-06-20 14:08:16","AP02EDTM":"2022-06-20 20:08:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-20","EOSDY":1096,"LSTALVDT":"2022-07-05","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7640,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.19588,"AVALU":"mg/L","BASE2":10.37558,"BASE":8.19588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.1797,"PCHG2":-21.00795,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-15 02:08:16","ADY":116,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-180","SUBJID":"id-180","SITEID":"RUS-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.62272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-17","TRTSDTM":"2019-06-21 02:08:16","TRTEDTM":"2022-06-20 20:08:16","TRT01SDTM":"2019-06-21 02:08:16","TRT01EDTM":"2021-06-20 14:08:16","TRT02SDTM":"2021-06-20 14:08:16","TRT02EDTM":"2022-06-20 20:08:16","AP01SDTM":"2019-06-21 02:08:16","AP01EDTM":"2021-06-20 14:08:16","AP02SDTM":"2021-06-20 14:08:16","AP02EDTM":"2022-06-20 20:08:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-20","EOSDY":1096,"LSTALVDT":"2022-07-05","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6567,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.61643,"AVALU":"mg/L","BASE2":10.37558,"BASE":8.19588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.75915,"PCHG2":-16.95469,"CHG":0.42055,"PCHG":5.13123,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-15 02:08:16","ADY":329,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-180","SUBJID":"id-180","SITEID":"RUS-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.62272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-17","TRTSDTM":"2019-06-21 02:08:16","TRTEDTM":"2022-06-20 20:08:16","TRT01SDTM":"2019-06-21 02:08:16","TRT01EDTM":"2021-06-20 14:08:16","TRT02SDTM":"2021-06-20 14:08:16","TRT02EDTM":"2022-06-20 20:08:16","AP01SDTM":"2019-06-21 02:08:16","AP01EDTM":"2021-06-20 14:08:16","AP02SDTM":"2021-06-20 14:08:16","AP02EDTM":"2022-06-20 20:08:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-20","EOSDY":1096,"LSTALVDT":"2022-07-05","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7973,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.5112,"AVALU":"mg/L","BASE2":10.37558,"BASE":8.19588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.86438,"PCHG2":-17.96894,"CHG":0.31532,"PCHG":3.84724,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-30 02:08:16","ADY":558,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-180","SUBJID":"id-180","SITEID":"RUS-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.62272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-17","TRTSDTM":"2019-06-21 02:08:16","TRTEDTM":"2022-06-20 20:08:16","TRT01SDTM":"2019-06-21 02:08:16","TRT01EDTM":"2021-06-20 14:08:16","TRT02SDTM":"2021-06-20 14:08:16","TRT02EDTM":"2022-06-20 20:08:16","AP01SDTM":"2019-06-21 02:08:16","AP01EDTM":"2021-06-20 14:08:16","AP02SDTM":"2021-06-20 14:08:16","AP02EDTM":"2022-06-20 20:08:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-20","EOSDY":1096,"LSTALVDT":"2022-07-05","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3545,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.92793,"AVALU":"mg/L","BASE2":10.37558,"BASE":8.19588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.44765,"PCHG2":-13.95246,"CHG":0.73205,"PCHG":8.93191,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-13 02:08:16","ADY":603,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-180","SUBJID":"id-180","SITEID":"RUS-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.62272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-17","TRTSDTM":"2019-06-21 02:08:16","TRTEDTM":"2022-06-20 20:08:16","TRT01SDTM":"2019-06-21 02:08:16","TRT01EDTM":"2021-06-20 14:08:16","TRT02SDTM":"2021-06-20 14:08:16","TRT02EDTM":"2022-06-20 20:08:16","AP01SDTM":"2019-06-21 02:08:16","AP01EDTM":"2021-06-20 14:08:16","AP02SDTM":"2021-06-20 14:08:16","AP02EDTM":"2022-06-20 20:08:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-20","EOSDY":1096,"LSTALVDT":"2022-07-05","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3376,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.49628,"AVALU":"mg/L","BASE2":10.37558,"BASE":8.19588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.8793,"PCHG2":-18.11272,"CHG":0.3004,"PCHG":3.66521,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-16 02:08:16","ADY":1030,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-180","SUBJID":"id-180","SITEID":"RUS-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.62272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-17","TRTSDTM":"2019-06-21 02:08:16","TRTEDTM":"2022-06-20 20:08:16","TRT01SDTM":"2019-06-21 02:08:16","TRT01EDTM":"2021-06-20 14:08:16","TRT02SDTM":"2021-06-20 14:08:16","TRT02EDTM":"2022-06-20 20:08:16","AP01SDTM":"2019-06-21 02:08:16","AP01EDTM":"2021-06-20 14:08:16","AP02SDTM":"2021-06-20 14:08:16","AP02EDTM":"2022-06-20 20:08:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-20","EOSDY":1096,"LSTALVDT":"2022-07-05","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6252,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.67815,"AVALU":"mg/L","BASE2":10.37558,"BASE":8.19588,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.69744,"PCHG2":-16.35991,"CHG":0.48226,"PCHG":5.88419,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-22 02:08:16","ADY":1036,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-180","SUBJID":"id-180","SITEID":"RUS-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.62272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-17","TRTSDTM":"2019-06-21 02:08:16","TRTEDTM":"2022-06-20 20:08:16","TRT01SDTM":"2019-06-21 02:08:16","TRT01EDTM":"2021-06-20 14:08:16","TRT02SDTM":"2021-06-20 14:08:16","TRT02EDTM":"2022-06-20 20:08:16","AP01SDTM":"2019-06-21 02:08:16","AP01EDTM":"2021-06-20 14:08:16","AP02SDTM":"2021-06-20 14:08:16","AP02EDTM":"2022-06-20 20:08:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-20","EOSDY":1096,"LSTALVDT":"2022-07-05","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1354,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90996,"AVALU":"g/L","BASE2":2.90996,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-14 02:08:16","ADY":23,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-180","SUBJID":"id-180","SITEID":"RUS-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.62272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-17","TRTSDTM":"2019-06-21 02:08:16","TRTEDTM":"2022-06-20 20:08:16","TRT01SDTM":"2019-06-21 02:08:16","TRT01EDTM":"2021-06-20 14:08:16","TRT02SDTM":"2021-06-20 14:08:16","TRT02EDTM":"2022-06-20 20:08:16","AP01SDTM":"2019-06-21 02:08:16","AP01EDTM":"2021-06-20 14:08:16","AP02SDTM":"2021-06-20 14:08:16","AP02EDTM":"2022-06-20 20:08:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-20","EOSDY":1096,"LSTALVDT":"2022-07-05","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3016,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7842,"AVALU":"g/L","BASE2":2.90996,"BASE":2.7842,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.12576,"PCHG2":-4.32155,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-10-15 02:08:16","ADY":116,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-180","SUBJID":"id-180","SITEID":"RUS-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.62272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-17","TRTSDTM":"2019-06-21 02:08:16","TRTEDTM":"2022-06-20 20:08:16","TRT01SDTM":"2019-06-21 02:08:16","TRT01EDTM":"2021-06-20 14:08:16","TRT02SDTM":"2021-06-20 14:08:16","TRT02EDTM":"2022-06-20 20:08:16","AP01SDTM":"2019-06-21 02:08:16","AP01EDTM":"2021-06-20 14:08:16","AP02SDTM":"2021-06-20 14:08:16","AP02EDTM":"2022-06-20 20:08:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-20","EOSDY":1096,"LSTALVDT":"2022-07-05","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1746,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93617,"AVALU":"g/L","BASE2":2.90996,"BASE":2.7842,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02621,"PCHG2":0.90082,"CHG":0.15197,"PCHG":5.45825,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-15 02:08:16","ADY":329,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-180","SUBJID":"id-180","SITEID":"RUS-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.62272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-17","TRTSDTM":"2019-06-21 02:08:16","TRTEDTM":"2022-06-20 20:08:16","TRT01SDTM":"2019-06-21 02:08:16","TRT01EDTM":"2021-06-20 14:08:16","TRT02SDTM":"2021-06-20 14:08:16","TRT02EDTM":"2022-06-20 20:08:16","AP01SDTM":"2019-06-21 02:08:16","AP01EDTM":"2021-06-20 14:08:16","AP02SDTM":"2021-06-20 14:08:16","AP02EDTM":"2022-06-20 20:08:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-20","EOSDY":1096,"LSTALVDT":"2022-07-05","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4745,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91056,"AVALU":"g/L","BASE2":2.90996,"BASE":2.7842,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0006,"PCHG2":0.02049,"CHG":0.12635,"PCHG":4.53816,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-30 02:08:16","ADY":558,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-180","SUBJID":"id-180","SITEID":"RUS-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.62272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-17","TRTSDTM":"2019-06-21 02:08:16","TRTEDTM":"2022-06-20 20:08:16","TRT01SDTM":"2019-06-21 02:08:16","TRT01EDTM":"2021-06-20 14:08:16","TRT02SDTM":"2021-06-20 14:08:16","TRT02EDTM":"2022-06-20 20:08:16","AP01SDTM":"2019-06-21 02:08:16","AP01EDTM":"2021-06-20 14:08:16","AP02SDTM":"2021-06-20 14:08:16","AP02EDTM":"2022-06-20 20:08:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-20","EOSDY":1096,"LSTALVDT":"2022-07-05","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4124,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81409,"AVALU":"g/L","BASE2":2.90996,"BASE":2.7842,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09587,"PCHG2":-3.29457,"CHG":0.02988,"PCHG":1.07337,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-13 02:08:16","ADY":603,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-180","SUBJID":"id-180","SITEID":"RUS-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.62272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-17","TRTSDTM":"2019-06-21 02:08:16","TRTEDTM":"2022-06-20 20:08:16","TRT01SDTM":"2019-06-21 02:08:16","TRT01EDTM":"2021-06-20 14:08:16","TRT02SDTM":"2021-06-20 14:08:16","TRT02EDTM":"2022-06-20 20:08:16","AP01SDTM":"2019-06-21 02:08:16","AP01EDTM":"2021-06-20 14:08:16","AP02SDTM":"2021-06-20 14:08:16","AP02EDTM":"2022-06-20 20:08:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-20","EOSDY":1096,"LSTALVDT":"2022-07-05","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3255,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86095,"AVALU":"g/L","BASE2":2.90996,"BASE":2.7842,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04901,"PCHG2":-1.6841,"CHG":0.07675,"PCHG":2.75658,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-16 02:08:16","ADY":1030,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-180","SUBJID":"id-180","SITEID":"RUS-4","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"A","STRATA2":"S1","BMRKR1":1.62272,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-17","TRTSDTM":"2019-06-21 02:08:16","TRTEDTM":"2022-06-20 20:08:16","TRT01SDTM":"2019-06-21 02:08:16","TRT01EDTM":"2021-06-20 14:08:16","TRT02SDTM":"2021-06-20 14:08:16","TRT02EDTM":"2022-06-20 20:08:16","AP01SDTM":"2019-06-21 02:08:16","AP01EDTM":"2021-06-20 14:08:16","AP02SDTM":"2021-06-20 14:08:16","AP02EDTM":"2022-06-20 20:08:16","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-06-20","EOSDY":1096,"LSTALVDT":"2022-07-05","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1056,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79657,"AVALU":"g/L","BASE2":2.90996,"BASE":2.7842,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11339,"PCHG2":-3.89676,"CHG":0.01236,"PCHG":0.44398,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-22 02:08:16","ADY":1036,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-6","SUBJID":"id-6","SITEID":"RUS-4","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.9442,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-31","TRTSDTM":"2019-04-03 01:01:46","TRTEDTM":"2022-04-02 19:01:46","TRT01SDTM":"2019-04-03 01:01:46","TRT01EDTM":"2021-04-02 13:01:46","TRT02SDTM":"2021-04-02 13:01:46","TRT02EDTM":"2022-04-02 19:01:46","AP01SDTM":"2019-04-03 01:01:46","AP01EDTM":"2021-04-02 13:01:46","AP02SDTM":"2021-04-02 13:01:46","AP02EDTM":"2022-04-02 19:01:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-02","EOSDY":1096,"LSTALVDT":"2022-04-13","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4135,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.18977,"AVALU":"U/L","BASE2":27.18977,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-13 01:01:46","ADY":345,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-6","SUBJID":"id-6","SITEID":"RUS-4","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.9442,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-31","TRTSDTM":"2019-04-03 01:01:46","TRTEDTM":"2022-04-02 19:01:46","TRT01SDTM":"2019-04-03 01:01:46","TRT01EDTM":"2021-04-02 13:01:46","TRT02SDTM":"2021-04-02 13:01:46","TRT02EDTM":"2022-04-02 19:01:46","AP01SDTM":"2019-04-03 01:01:46","AP01EDTM":"2021-04-02 13:01:46","AP02SDTM":"2021-04-02 13:01:46","AP02EDTM":"2022-04-02 19:01:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-02","EOSDY":1096,"LSTALVDT":"2022-04-13","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5479,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.828,"AVALU":"U/L","BASE2":27.18977,"BASE":12.828,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-14.36177,"PCHG2":-52.82048,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-17 01:01:46","ADY":410,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-6","SUBJID":"id-6","SITEID":"RUS-4","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.9442,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-31","TRTSDTM":"2019-04-03 01:01:46","TRTEDTM":"2022-04-02 19:01:46","TRT01SDTM":"2019-04-03 01:01:46","TRT01EDTM":"2021-04-02 13:01:46","TRT02SDTM":"2021-04-02 13:01:46","TRT02EDTM":"2022-04-02 19:01:46","AP01SDTM":"2019-04-03 01:01:46","AP01EDTM":"2021-04-02 13:01:46","AP02SDTM":"2021-04-02 13:01:46","AP02EDTM":"2022-04-02 19:01:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-02","EOSDY":1096,"LSTALVDT":"2022-04-13","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1304,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.19806,"AVALU":"U/L","BASE2":27.18977,"BASE":12.828,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.99171,"PCHG2":-29.39233,"CHG":6.37006,"PCHG":49.65745,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-27 01:01:46","ADY":696,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-6","SUBJID":"id-6","SITEID":"RUS-4","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.9442,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-31","TRTSDTM":"2019-04-03 01:01:46","TRTEDTM":"2022-04-02 19:01:46","TRT01SDTM":"2019-04-03 01:01:46","TRT01EDTM":"2021-04-02 13:01:46","TRT02SDTM":"2021-04-02 13:01:46","TRT02EDTM":"2022-04-02 19:01:46","AP01SDTM":"2019-04-03 01:01:46","AP01EDTM":"2021-04-02 13:01:46","AP02SDTM":"2021-04-02 13:01:46","AP02EDTM":"2022-04-02 19:01:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-02","EOSDY":1096,"LSTALVDT":"2022-04-13","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5934,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.34635,"AVALU":"U/L","BASE2":27.18977,"BASE":12.828,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.84343,"PCHG2":-43.55839,"CHG":2.51834,"PCHG":19.6316,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-23 01:01:46","ADY":904,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-6","SUBJID":"id-6","SITEID":"RUS-4","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.9442,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-31","TRTSDTM":"2019-04-03 01:01:46","TRTEDTM":"2022-04-02 19:01:46","TRT01SDTM":"2019-04-03 01:01:46","TRT01EDTM":"2021-04-02 13:01:46","TRT02SDTM":"2021-04-02 13:01:46","TRT02EDTM":"2022-04-02 19:01:46","AP01SDTM":"2019-04-03 01:01:46","AP01EDTM":"2021-04-02 13:01:46","AP02SDTM":"2021-04-02 13:01:46","AP02EDTM":"2022-04-02 19:01:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-02","EOSDY":1096,"LSTALVDT":"2022-04-13","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2539,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.7367,"AVALU":"U/L","BASE2":27.18977,"BASE":12.828,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.45308,"PCHG2":-45.8006,"CHG":1.90869,"PCHG":14.8791,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-30 01:01:46","ADY":911,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-6","SUBJID":"id-6","SITEID":"RUS-4","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.9442,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-31","TRTSDTM":"2019-04-03 01:01:46","TRTEDTM":"2022-04-02 19:01:46","TRT01SDTM":"2019-04-03 01:01:46","TRT01EDTM":"2021-04-02 13:01:46","TRT02SDTM":"2021-04-02 13:01:46","TRT02EDTM":"2022-04-02 19:01:46","AP01SDTM":"2019-04-03 01:01:46","AP01EDTM":"2021-04-02 13:01:46","AP02SDTM":"2021-04-02 13:01:46","AP02EDTM":"2022-04-02 19:01:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-02","EOSDY":1096,"LSTALVDT":"2022-04-13","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6898,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.53191,"AVALU":"U/L","BASE2":27.18977,"BASE":12.828,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.65786,"PCHG2":-31.84234,"CHG":5.70391,"PCHG":44.4645,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-06 01:01:46","ADY":978,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-6","SUBJID":"id-6","SITEID":"RUS-4","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.9442,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-31","TRTSDTM":"2019-04-03 01:01:46","TRTEDTM":"2022-04-02 19:01:46","TRT01SDTM":"2019-04-03 01:01:46","TRT01EDTM":"2021-04-02 13:01:46","TRT02SDTM":"2021-04-02 13:01:46","TRT02EDTM":"2022-04-02 19:01:46","AP01SDTM":"2019-04-03 01:01:46","AP01EDTM":"2021-04-02 13:01:46","AP02SDTM":"2021-04-02 13:01:46","AP02EDTM":"2022-04-02 19:01:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-02","EOSDY":1096,"LSTALVDT":"2022-04-13","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1616,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.59887,"AVALU":"U/L","BASE2":27.18977,"BASE":12.828,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-25.59091,"PCHG2":-94.1196,"CHG":-11.22914,"PCHG":-87.53612,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2022-03-08 01:01:46","ADY":1070,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-6","SUBJID":"id-6","SITEID":"RUS-4","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.9442,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-31","TRTSDTM":"2019-04-03 01:01:46","TRTEDTM":"2022-04-02 19:01:46","TRT01SDTM":"2019-04-03 01:01:46","TRT01EDTM":"2021-04-02 13:01:46","TRT02SDTM":"2021-04-02 13:01:46","TRT02EDTM":"2022-04-02 19:01:46","AP01SDTM":"2019-04-03 01:01:46","AP01EDTM":"2021-04-02 13:01:46","AP02SDTM":"2021-04-02 13:01:46","AP02EDTM":"2022-04-02 19:01:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-02","EOSDY":1096,"LSTALVDT":"2022-04-13","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3457,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.82237,"AVALU":"mg/L","BASE2":8.82237,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-13 01:01:46","ADY":345,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-6","SUBJID":"id-6","SITEID":"RUS-4","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.9442,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-31","TRTSDTM":"2019-04-03 01:01:46","TRTEDTM":"2022-04-02 19:01:46","TRT01SDTM":"2019-04-03 01:01:46","TRT01EDTM":"2021-04-02 13:01:46","TRT02SDTM":"2021-04-02 13:01:46","TRT02EDTM":"2022-04-02 19:01:46","AP01SDTM":"2019-04-03 01:01:46","AP01EDTM":"2021-04-02 13:01:46","AP02SDTM":"2021-04-02 13:01:46","AP02EDTM":"2022-04-02 19:01:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-02","EOSDY":1096,"LSTALVDT":"2022-04-13","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5449,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.5016,"AVALU":"mg/L","BASE2":8.82237,"BASE":8.5016,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.32077,"PCHG2":-3.63582,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-17 01:01:46","ADY":410,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-6","SUBJID":"id-6","SITEID":"RUS-4","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.9442,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-31","TRTSDTM":"2019-04-03 01:01:46","TRTEDTM":"2022-04-02 19:01:46","TRT01SDTM":"2019-04-03 01:01:46","TRT01EDTM":"2021-04-02 13:01:46","TRT02SDTM":"2021-04-02 13:01:46","TRT02EDTM":"2022-04-02 19:01:46","AP01SDTM":"2019-04-03 01:01:46","AP01EDTM":"2021-04-02 13:01:46","AP02SDTM":"2021-04-02 13:01:46","AP02EDTM":"2022-04-02 19:01:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-02","EOSDY":1096,"LSTALVDT":"2022-04-13","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4487,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.75729,"AVALU":"mg/L","BASE2":8.82237,"BASE":8.5016,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.06508,"PCHG2":-12.07248,"CHG":-0.74431,"PCHG":-8.75497,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-02-27 01:01:46","ADY":696,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-6","SUBJID":"id-6","SITEID":"RUS-4","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.9442,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-31","TRTSDTM":"2019-04-03 01:01:46","TRTEDTM":"2022-04-02 19:01:46","TRT01SDTM":"2019-04-03 01:01:46","TRT01EDTM":"2021-04-02 13:01:46","TRT02SDTM":"2021-04-02 13:01:46","TRT02EDTM":"2022-04-02 19:01:46","AP01SDTM":"2019-04-03 01:01:46","AP01EDTM":"2021-04-02 13:01:46","AP02SDTM":"2021-04-02 13:01:46","AP02EDTM":"2022-04-02 19:01:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-02","EOSDY":1096,"LSTALVDT":"2022-04-13","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7228,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.3823,"AVALU":"mg/L","BASE2":8.82237,"BASE":8.5016,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.55993,"PCHG2":6.34672,"CHG":0.8807,"PCHG":10.35918,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-23 01:01:46","ADY":904,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-6","SUBJID":"id-6","SITEID":"RUS-4","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.9442,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-31","TRTSDTM":"2019-04-03 01:01:46","TRTEDTM":"2022-04-02 19:01:46","TRT01SDTM":"2019-04-03 01:01:46","TRT01EDTM":"2021-04-02 13:01:46","TRT02SDTM":"2021-04-02 13:01:46","TRT02EDTM":"2022-04-02 19:01:46","AP01SDTM":"2019-04-03 01:01:46","AP01EDTM":"2021-04-02 13:01:46","AP02SDTM":"2021-04-02 13:01:46","AP02EDTM":"2022-04-02 19:01:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-02","EOSDY":1096,"LSTALVDT":"2022-04-13","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1934,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.3158,"AVALU":"mg/L","BASE2":8.82237,"BASE":8.5016,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.49343,"PCHG2":5.59293,"CHG":0.81419,"PCHG":9.57695,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-30 01:01:46","ADY":911,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-6","SUBJID":"id-6","SITEID":"RUS-4","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.9442,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-31","TRTSDTM":"2019-04-03 01:01:46","TRTEDTM":"2022-04-02 19:01:46","TRT01SDTM":"2019-04-03 01:01:46","TRT01EDTM":"2021-04-02 13:01:46","TRT02SDTM":"2021-04-02 13:01:46","TRT02EDTM":"2022-04-02 19:01:46","AP01SDTM":"2019-04-03 01:01:46","AP01EDTM":"2021-04-02 13:01:46","AP02SDTM":"2021-04-02 13:01:46","AP02EDTM":"2022-04-02 19:01:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-02","EOSDY":1096,"LSTALVDT":"2022-04-13","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3358,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.74767,"AVALU":"mg/L","BASE2":8.82237,"BASE":8.5016,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.0747,"PCHG2":-12.18156,"CHG":-0.75394,"PCHG":-8.86817,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-12-06 01:01:46","ADY":978,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-6","SUBJID":"id-6","SITEID":"RUS-4","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.9442,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-31","TRTSDTM":"2019-04-03 01:01:46","TRTEDTM":"2022-04-02 19:01:46","TRT01SDTM":"2019-04-03 01:01:46","TRT01EDTM":"2021-04-02 13:01:46","TRT02SDTM":"2021-04-02 13:01:46","TRT02EDTM":"2022-04-02 19:01:46","AP01SDTM":"2019-04-03 01:01:46","AP01EDTM":"2021-04-02 13:01:46","AP02SDTM":"2021-04-02 13:01:46","AP02EDTM":"2022-04-02 19:01:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-02","EOSDY":1096,"LSTALVDT":"2022-04-13","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":721,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.60853,"AVALU":"mg/L","BASE2":8.82237,"BASE":8.5016,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.78616,"PCHG2":8.91098,"CHG":1.10693,"PCHG":13.02019,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-08 01:01:46","ADY":1070,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-6","SUBJID":"id-6","SITEID":"RUS-4","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.9442,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-31","TRTSDTM":"2019-04-03 01:01:46","TRTEDTM":"2022-04-02 19:01:46","TRT01SDTM":"2019-04-03 01:01:46","TRT01EDTM":"2021-04-02 13:01:46","TRT02SDTM":"2021-04-02 13:01:46","TRT02EDTM":"2022-04-02 19:01:46","AP01SDTM":"2019-04-03 01:01:46","AP01EDTM":"2021-04-02 13:01:46","AP02SDTM":"2021-04-02 13:01:46","AP02EDTM":"2022-04-02 19:01:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-02","EOSDY":1096,"LSTALVDT":"2022-04-13","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3823,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82855,"AVALU":"g/L","BASE2":2.82855,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-03-13 01:01:46","ADY":345,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-6","SUBJID":"id-6","SITEID":"RUS-4","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.9442,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-31","TRTSDTM":"2019-04-03 01:01:46","TRTEDTM":"2022-04-02 19:01:46","TRT01SDTM":"2019-04-03 01:01:46","TRT01EDTM":"2021-04-02 13:01:46","TRT02SDTM":"2021-04-02 13:01:46","TRT02EDTM":"2022-04-02 19:01:46","AP01SDTM":"2019-04-03 01:01:46","AP01EDTM":"2021-04-02 13:01:46","AP02SDTM":"2021-04-02 13:01:46","AP02EDTM":"2022-04-02 19:01:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-02","EOSDY":1096,"LSTALVDT":"2022-04-13","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":294,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90465,"AVALU":"g/L","BASE2":2.82855,"BASE":2.90465,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.07611,"PCHG2":2.69062,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-17 01:01:46","ADY":410,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-6","SUBJID":"id-6","SITEID":"RUS-4","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.9442,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-31","TRTSDTM":"2019-04-03 01:01:46","TRTEDTM":"2022-04-02 19:01:46","TRT01SDTM":"2019-04-03 01:01:46","TRT01EDTM":"2021-04-02 13:01:46","TRT02SDTM":"2021-04-02 13:01:46","TRT02EDTM":"2022-04-02 19:01:46","AP01SDTM":"2019-04-03 01:01:46","AP01EDTM":"2021-04-02 13:01:46","AP02SDTM":"2021-04-02 13:01:46","AP02EDTM":"2022-04-02 19:01:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-02","EOSDY":1096,"LSTALVDT":"2022-04-13","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6710,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93496,"AVALU":"g/L","BASE2":2.82855,"BASE":2.90465,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10641,"PCHG2":3.76213,"CHG":0.03031,"PCHG":1.04343,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-27 01:01:46","ADY":696,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-6","SUBJID":"id-6","SITEID":"RUS-4","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.9442,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-31","TRTSDTM":"2019-04-03 01:01:46","TRTEDTM":"2022-04-02 19:01:46","TRT01SDTM":"2019-04-03 01:01:46","TRT01EDTM":"2021-04-02 13:01:46","TRT02SDTM":"2021-04-02 13:01:46","TRT02EDTM":"2022-04-02 19:01:46","AP01SDTM":"2019-04-03 01:01:46","AP01EDTM":"2021-04-02 13:01:46","AP02SDTM":"2021-04-02 13:01:46","AP02EDTM":"2022-04-02 19:01:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-02","EOSDY":1096,"LSTALVDT":"2022-04-13","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4856,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89214,"AVALU":"g/L","BASE2":2.82855,"BASE":2.90465,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06359,"PCHG2":2.24831,"CHG":-0.01251,"PCHG":-0.43072,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-23 01:01:46","ADY":904,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-6","SUBJID":"id-6","SITEID":"RUS-4","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.9442,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-31","TRTSDTM":"2019-04-03 01:01:46","TRTEDTM":"2022-04-02 19:01:46","TRT01SDTM":"2019-04-03 01:01:46","TRT01EDTM":"2021-04-02 13:01:46","TRT02SDTM":"2021-04-02 13:01:46","TRT02EDTM":"2022-04-02 19:01:46","AP01SDTM":"2019-04-03 01:01:46","AP01EDTM":"2021-04-02 13:01:46","AP02SDTM":"2021-04-02 13:01:46","AP02EDTM":"2022-04-02 19:01:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-02","EOSDY":1096,"LSTALVDT":"2022-04-13","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2341,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9686,"AVALU":"g/L","BASE2":2.82855,"BASE":2.90465,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14005,"PCHG2":4.95136,"CHG":0.06395,"PCHG":2.20151,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-30 01:01:46","ADY":911,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-6","SUBJID":"id-6","SITEID":"RUS-4","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.9442,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-31","TRTSDTM":"2019-04-03 01:01:46","TRTEDTM":"2022-04-02 19:01:46","TRT01SDTM":"2019-04-03 01:01:46","TRT01EDTM":"2021-04-02 13:01:46","TRT02SDTM":"2021-04-02 13:01:46","TRT02EDTM":"2022-04-02 19:01:46","AP01SDTM":"2019-04-03 01:01:46","AP01EDTM":"2021-04-02 13:01:46","AP02SDTM":"2021-04-02 13:01:46","AP02EDTM":"2022-04-02 19:01:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-02","EOSDY":1096,"LSTALVDT":"2022-04-13","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4077,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.08476,"AVALU":"g/L","BASE2":2.82855,"BASE":2.90465,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.25621,"PCHG2":9.05809,"CHG":0.18011,"PCHG":6.20064,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-12-06 01:01:46","ADY":978,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-4-id-6","SUBJID":"id-6","SITEID":"RUS-4","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-4","INVNAM":"Dr. RUS-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":4.9442,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-31","TRTSDTM":"2019-04-03 01:01:46","TRTEDTM":"2022-04-02 19:01:46","TRT01SDTM":"2019-04-03 01:01:46","TRT01EDTM":"2021-04-02 13:01:46","TRT02SDTM":"2021-04-02 13:01:46","TRT02EDTM":"2022-04-02 19:01:46","AP01SDTM":"2019-04-03 01:01:46","AP01EDTM":"2021-04-02 13:01:46","AP02SDTM":"2021-04-02 13:01:46","AP02EDTM":"2022-04-02 19:01:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-02","EOSDY":1096,"LSTALVDT":"2022-04-13","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1812,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84345,"AVALU":"g/L","BASE2":2.82855,"BASE":2.90465,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0149,"PCHG2":0.52671,"CHG":-0.06121,"PCHG":-2.10721,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-08 01:01:46","ADY":1070,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-5-id-29","SUBJID":"id-29","SITEID":"RUS-5","AGE":58,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-5","INVNAM":"Dr. RUS-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.11508,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-05","TRTSDTM":"2020-12-08 01:10:31","TRTEDTM":"2023-12-08 19:10:31","TRT01SDTM":"2020-12-08 01:10:31","TRT01EDTM":"2022-12-08 13:10:31","TRT02SDTM":"2022-12-08 13:10:31","TRT02EDTM":"2023-12-08 19:10:31","AP01SDTM":"2020-12-08 01:10:31","AP01EDTM":"2022-12-08 13:10:31","AP02SDTM":"2022-12-08 13:10:31","AP02EDTM":"2023-12-08 19:10:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-08","EOSDY":1096,"LSTALVDT":"2023-12-25","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1862,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.70021,"AVALU":"U/L","BASE2":13.70021,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-13 01:10:31","ADY":187,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-5-id-29","SUBJID":"id-29","SITEID":"RUS-5","AGE":58,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-5","INVNAM":"Dr. RUS-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.11508,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-05","TRTSDTM":"2020-12-08 01:10:31","TRTEDTM":"2023-12-08 19:10:31","TRT01SDTM":"2020-12-08 01:10:31","TRT01EDTM":"2022-12-08 13:10:31","TRT02SDTM":"2022-12-08 13:10:31","TRT02EDTM":"2023-12-08 19:10:31","AP01SDTM":"2020-12-08 01:10:31","AP01EDTM":"2022-12-08 13:10:31","AP02SDTM":"2022-12-08 13:10:31","AP02EDTM":"2023-12-08 19:10:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-08","EOSDY":1096,"LSTALVDT":"2023-12-25","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2173,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.64869,"AVALU":"U/L","BASE2":13.70021,"BASE":24.64869,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":10.94848,"PCHG2":79.91466,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-31 01:10:31","ADY":235,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-5-id-29","SUBJID":"id-29","SITEID":"RUS-5","AGE":58,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-5","INVNAM":"Dr. RUS-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.11508,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-05","TRTSDTM":"2020-12-08 01:10:31","TRTEDTM":"2023-12-08 19:10:31","TRT01SDTM":"2020-12-08 01:10:31","TRT01EDTM":"2022-12-08 13:10:31","TRT02SDTM":"2022-12-08 13:10:31","TRT02EDTM":"2023-12-08 19:10:31","AP01SDTM":"2020-12-08 01:10:31","AP01EDTM":"2022-12-08 13:10:31","AP02SDTM":"2022-12-08 13:10:31","AP02EDTM":"2023-12-08 19:10:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-08","EOSDY":1096,"LSTALVDT":"2023-12-25","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7447,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.09356,"AVALU":"U/L","BASE2":13.70021,"BASE":24.64869,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.60665,"PCHG2":-70.12047,"CHG":-20.55513,"PCHG":-83.39239,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2022-06-29 01:10:31","ADY":568,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-5-id-29","SUBJID":"id-29","SITEID":"RUS-5","AGE":58,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-5","INVNAM":"Dr. RUS-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.11508,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-05","TRTSDTM":"2020-12-08 01:10:31","TRTEDTM":"2023-12-08 19:10:31","TRT01SDTM":"2020-12-08 01:10:31","TRT01EDTM":"2022-12-08 13:10:31","TRT02SDTM":"2022-12-08 13:10:31","TRT02EDTM":"2023-12-08 19:10:31","AP01SDTM":"2020-12-08 01:10:31","AP01EDTM":"2022-12-08 13:10:31","AP02SDTM":"2022-12-08 13:10:31","AP02EDTM":"2023-12-08 19:10:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-08","EOSDY":1096,"LSTALVDT":"2023-12-25","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6695,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.91771,"AVALU":"U/L","BASE2":13.70021,"BASE":24.64869,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.7825,"PCHG2":-56.80572,"CHG":-18.73098,"PCHG":-75.99179,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2022-08-18 01:10:31","ADY":618,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-5-id-29","SUBJID":"id-29","SITEID":"RUS-5","AGE":58,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-5","INVNAM":"Dr. RUS-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.11508,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-05","TRTSDTM":"2020-12-08 01:10:31","TRTEDTM":"2023-12-08 19:10:31","TRT01SDTM":"2020-12-08 01:10:31","TRT01EDTM":"2022-12-08 13:10:31","TRT02SDTM":"2022-12-08 13:10:31","TRT02EDTM":"2023-12-08 19:10:31","AP01SDTM":"2020-12-08 01:10:31","AP01EDTM":"2022-12-08 13:10:31","AP02SDTM":"2022-12-08 13:10:31","AP02EDTM":"2023-12-08 19:10:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-08","EOSDY":1096,"LSTALVDT":"2023-12-25","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":173,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.13208,"AVALU":"U/L","BASE2":13.70021,"BASE":24.64869,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.56814,"PCHG2":-18.74523,"CHG":-13.51661,"PCHG":-54.83705,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-03 01:10:31","ADY":695,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-5-id-29","SUBJID":"id-29","SITEID":"RUS-5","AGE":58,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-5","INVNAM":"Dr. RUS-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.11508,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-05","TRTSDTM":"2020-12-08 01:10:31","TRTEDTM":"2023-12-08 19:10:31","TRT01SDTM":"2020-12-08 01:10:31","TRT01EDTM":"2022-12-08 13:10:31","TRT02SDTM":"2022-12-08 13:10:31","TRT02EDTM":"2023-12-08 19:10:31","AP01SDTM":"2020-12-08 01:10:31","AP01EDTM":"2022-12-08 13:10:31","AP02SDTM":"2022-12-08 13:10:31","AP02EDTM":"2023-12-08 19:10:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-08","EOSDY":1096,"LSTALVDT":"2023-12-25","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2170,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":36.87484,"AVALU":"U/L","BASE2":13.70021,"BASE":24.64869,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":23.17463,"PCHG2":169.15527,"CHG":12.22615,"PCHG":49.60163,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-06 01:10:31","ADY":971,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-5-id-29","SUBJID":"id-29","SITEID":"RUS-5","AGE":58,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-5","INVNAM":"Dr. RUS-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.11508,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-05","TRTSDTM":"2020-12-08 01:10:31","TRTEDTM":"2023-12-08 19:10:31","TRT01SDTM":"2020-12-08 01:10:31","TRT01EDTM":"2022-12-08 13:10:31","TRT02SDTM":"2022-12-08 13:10:31","TRT02EDTM":"2023-12-08 19:10:31","AP01SDTM":"2020-12-08 01:10:31","AP01EDTM":"2022-12-08 13:10:31","AP02SDTM":"2022-12-08 13:10:31","AP02EDTM":"2023-12-08 19:10:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-08","EOSDY":1096,"LSTALVDT":"2023-12-25","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1800,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.16504,"AVALU":"U/L","BASE2":13.70021,"BASE":24.64869,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.53518,"PCHG2":-55.00044,"CHG":-18.48365,"PCHG":-74.98839,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2023-10-26 01:10:31","ADY":1052,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-5-id-29","SUBJID":"id-29","SITEID":"RUS-5","AGE":58,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-5","INVNAM":"Dr. RUS-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.11508,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-05","TRTSDTM":"2020-12-08 01:10:31","TRTEDTM":"2023-12-08 19:10:31","TRT01SDTM":"2020-12-08 01:10:31","TRT01EDTM":"2022-12-08 13:10:31","TRT02SDTM":"2022-12-08 13:10:31","TRT02EDTM":"2023-12-08 19:10:31","AP01SDTM":"2020-12-08 01:10:31","AP01EDTM":"2022-12-08 13:10:31","AP02SDTM":"2022-12-08 13:10:31","AP02EDTM":"2023-12-08 19:10:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-08","EOSDY":1096,"LSTALVDT":"2023-12-25","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2637,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.21994,"AVALU":"mg/L","BASE2":10.21994,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-06-13 01:10:31","ADY":187,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-5-id-29","SUBJID":"id-29","SITEID":"RUS-5","AGE":58,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-5","INVNAM":"Dr. RUS-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.11508,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-05","TRTSDTM":"2020-12-08 01:10:31","TRTEDTM":"2023-12-08 19:10:31","TRT01SDTM":"2020-12-08 01:10:31","TRT01EDTM":"2022-12-08 13:10:31","TRT02SDTM":"2022-12-08 13:10:31","TRT02EDTM":"2023-12-08 19:10:31","AP01SDTM":"2020-12-08 01:10:31","AP01EDTM":"2022-12-08 13:10:31","AP02SDTM":"2022-12-08 13:10:31","AP02EDTM":"2023-12-08 19:10:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-08","EOSDY":1096,"LSTALVDT":"2023-12-25","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7856,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.39346,"AVALU":"mg/L","BASE2":10.21994,"BASE":8.39346,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.82649,"PCHG2":-17.8718,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-31 01:10:31","ADY":235,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-5-id-29","SUBJID":"id-29","SITEID":"RUS-5","AGE":58,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-5","INVNAM":"Dr. RUS-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.11508,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-05","TRTSDTM":"2020-12-08 01:10:31","TRTEDTM":"2023-12-08 19:10:31","TRT01SDTM":"2020-12-08 01:10:31","TRT01EDTM":"2022-12-08 13:10:31","TRT02SDTM":"2022-12-08 13:10:31","TRT02EDTM":"2023-12-08 19:10:31","AP01SDTM":"2020-12-08 01:10:31","AP01EDTM":"2022-12-08 13:10:31","AP02SDTM":"2022-12-08 13:10:31","AP02EDTM":"2023-12-08 19:10:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-08","EOSDY":1096,"LSTALVDT":"2023-12-25","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":802,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.32132,"AVALU":"mg/L","BASE2":10.21994,"BASE":8.39346,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.89862,"PCHG2":-28.3624,"CHG":-1.07213,"PCHG":-12.77345,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-06-29 01:10:31","ADY":568,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-5-id-29","SUBJID":"id-29","SITEID":"RUS-5","AGE":58,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-5","INVNAM":"Dr. RUS-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.11508,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-05","TRTSDTM":"2020-12-08 01:10:31","TRTEDTM":"2023-12-08 19:10:31","TRT01SDTM":"2020-12-08 01:10:31","TRT01EDTM":"2022-12-08 13:10:31","TRT02SDTM":"2022-12-08 13:10:31","TRT02EDTM":"2023-12-08 19:10:31","AP01SDTM":"2020-12-08 01:10:31","AP01EDTM":"2022-12-08 13:10:31","AP02SDTM":"2022-12-08 13:10:31","AP02EDTM":"2023-12-08 19:10:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-08","EOSDY":1096,"LSTALVDT":"2023-12-25","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":969,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.16359,"AVALU":"mg/L","BASE2":10.21994,"BASE":8.39346,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.05636,"PCHG2":-10.33624,"CHG":0.77013,"PCHG":9.17536,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-18 01:10:31","ADY":618,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-5-id-29","SUBJID":"id-29","SITEID":"RUS-5","AGE":58,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-5","INVNAM":"Dr. RUS-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.11508,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-05","TRTSDTM":"2020-12-08 01:10:31","TRTEDTM":"2023-12-08 19:10:31","TRT01SDTM":"2020-12-08 01:10:31","TRT01EDTM":"2022-12-08 13:10:31","TRT02SDTM":"2022-12-08 13:10:31","TRT02EDTM":"2023-12-08 19:10:31","AP01SDTM":"2020-12-08 01:10:31","AP01EDTM":"2022-12-08 13:10:31","AP02SDTM":"2022-12-08 13:10:31","AP02EDTM":"2023-12-08 19:10:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-08","EOSDY":1096,"LSTALVDT":"2023-12-25","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6001,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.98834,"AVALU":"mg/L","BASE2":10.21994,"BASE":8.39346,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.2316,"PCHG2":-2.26618,"CHG":1.59489,"PCHG":19.00153,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-03 01:10:31","ADY":695,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-5-id-29","SUBJID":"id-29","SITEID":"RUS-5","AGE":58,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-5","INVNAM":"Dr. RUS-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.11508,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-05","TRTSDTM":"2020-12-08 01:10:31","TRTEDTM":"2023-12-08 19:10:31","TRT01SDTM":"2020-12-08 01:10:31","TRT01EDTM":"2022-12-08 13:10:31","TRT02SDTM":"2022-12-08 13:10:31","TRT02EDTM":"2023-12-08 19:10:31","AP01SDTM":"2020-12-08 01:10:31","AP01EDTM":"2022-12-08 13:10:31","AP02SDTM":"2022-12-08 13:10:31","AP02EDTM":"2023-12-08 19:10:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-08","EOSDY":1096,"LSTALVDT":"2023-12-25","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3844,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.69373,"AVALU":"mg/L","BASE2":10.21994,"BASE":8.39346,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.52621,"PCHG2":-14.93369,"CHG":0.30027,"PCHG":3.57747,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-06 01:10:31","ADY":971,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-5-id-29","SUBJID":"id-29","SITEID":"RUS-5","AGE":58,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-5","INVNAM":"Dr. RUS-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.11508,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-05","TRTSDTM":"2020-12-08 01:10:31","TRTEDTM":"2023-12-08 19:10:31","TRT01SDTM":"2020-12-08 01:10:31","TRT01EDTM":"2022-12-08 13:10:31","TRT02SDTM":"2022-12-08 13:10:31","TRT02EDTM":"2023-12-08 19:10:31","AP01SDTM":"2020-12-08 01:10:31","AP01EDTM":"2022-12-08 13:10:31","AP02SDTM":"2022-12-08 13:10:31","AP02EDTM":"2023-12-08 19:10:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-08","EOSDY":1096,"LSTALVDT":"2023-12-25","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3814,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.62923,"AVALU":"mg/L","BASE2":10.21994,"BASE":8.39346,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.59072,"PCHG2":-15.56482,"CHG":0.23577,"PCHG":2.809,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-10-26 01:10:31","ADY":1052,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-5-id-29","SUBJID":"id-29","SITEID":"RUS-5","AGE":58,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-5","INVNAM":"Dr. RUS-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.11508,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-05","TRTSDTM":"2020-12-08 01:10:31","TRTEDTM":"2023-12-08 19:10:31","TRT01SDTM":"2020-12-08 01:10:31","TRT01EDTM":"2022-12-08 13:10:31","TRT02SDTM":"2022-12-08 13:10:31","TRT02EDTM":"2023-12-08 19:10:31","AP01SDTM":"2020-12-08 01:10:31","AP01EDTM":"2022-12-08 13:10:31","AP02SDTM":"2022-12-08 13:10:31","AP02EDTM":"2023-12-08 19:10:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-08","EOSDY":1096,"LSTALVDT":"2023-12-25","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1407,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90092,"AVALU":"g/L","BASE2":2.90092,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-06-13 01:10:31","ADY":187,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-5-id-29","SUBJID":"id-29","SITEID":"RUS-5","AGE":58,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-5","INVNAM":"Dr. RUS-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.11508,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-05","TRTSDTM":"2020-12-08 01:10:31","TRTEDTM":"2023-12-08 19:10:31","TRT01SDTM":"2020-12-08 01:10:31","TRT01EDTM":"2022-12-08 13:10:31","TRT02SDTM":"2022-12-08 13:10:31","TRT02EDTM":"2023-12-08 19:10:31","AP01SDTM":"2020-12-08 01:10:31","AP01EDTM":"2022-12-08 13:10:31","AP02SDTM":"2022-12-08 13:10:31","AP02EDTM":"2023-12-08 19:10:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-08","EOSDY":1096,"LSTALVDT":"2023-12-25","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1761,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.14085,"AVALU":"g/L","BASE2":2.90092,"BASE":3.14085,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.23993,"PCHG2":8.27076,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2021-07-31 01:10:31","ADY":235,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-5-id-29","SUBJID":"id-29","SITEID":"RUS-5","AGE":58,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-5","INVNAM":"Dr. RUS-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.11508,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-05","TRTSDTM":"2020-12-08 01:10:31","TRTEDTM":"2023-12-08 19:10:31","TRT01SDTM":"2020-12-08 01:10:31","TRT01EDTM":"2022-12-08 13:10:31","TRT02SDTM":"2022-12-08 13:10:31","TRT02EDTM":"2023-12-08 19:10:31","AP01SDTM":"2020-12-08 01:10:31","AP01EDTM":"2022-12-08 13:10:31","AP02SDTM":"2022-12-08 13:10:31","AP02EDTM":"2023-12-08 19:10:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-08","EOSDY":1096,"LSTALVDT":"2023-12-25","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4763,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.0108,"AVALU":"g/L","BASE2":2.90092,"BASE":3.14085,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10988,"PCHG2":3.7877,"CHG":-0.13005,"PCHG":-4.1406,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"3","BTOXGR":"3","ADTM":"2022-06-29 01:10:31","ADY":568,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-5-id-29","SUBJID":"id-29","SITEID":"RUS-5","AGE":58,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-5","INVNAM":"Dr. RUS-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.11508,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-05","TRTSDTM":"2020-12-08 01:10:31","TRTEDTM":"2023-12-08 19:10:31","TRT01SDTM":"2020-12-08 01:10:31","TRT01EDTM":"2022-12-08 13:10:31","TRT02SDTM":"2022-12-08 13:10:31","TRT02EDTM":"2023-12-08 19:10:31","AP01SDTM":"2020-12-08 01:10:31","AP01EDTM":"2022-12-08 13:10:31","AP02SDTM":"2022-12-08 13:10:31","AP02EDTM":"2023-12-08 19:10:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-08","EOSDY":1096,"LSTALVDT":"2023-12-25","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1389,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78304,"AVALU":"g/L","BASE2":2.90092,"BASE":3.14085,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11788,"PCHG2":-4.06349,"CHG":-0.35781,"PCHG":-11.39205,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-08-18 01:10:31","ADY":618,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-5-id-29","SUBJID":"id-29","SITEID":"RUS-5","AGE":58,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-5","INVNAM":"Dr. RUS-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.11508,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-05","TRTSDTM":"2020-12-08 01:10:31","TRTEDTM":"2023-12-08 19:10:31","TRT01SDTM":"2020-12-08 01:10:31","TRT01EDTM":"2022-12-08 13:10:31","TRT02SDTM":"2022-12-08 13:10:31","TRT02EDTM":"2023-12-08 19:10:31","AP01SDTM":"2020-12-08 01:10:31","AP01EDTM":"2022-12-08 13:10:31","AP02SDTM":"2022-12-08 13:10:31","AP02EDTM":"2023-12-08 19:10:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-08","EOSDY":1096,"LSTALVDT":"2023-12-25","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1060,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.68485,"AVALU":"g/L","BASE2":2.90092,"BASE":3.14085,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21607,"PCHG2":-7.4484,"CHG":-0.456,"PCHG":-14.51838,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-11-03 01:10:31","ADY":695,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-5-id-29","SUBJID":"id-29","SITEID":"RUS-5","AGE":58,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-5","INVNAM":"Dr. RUS-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.11508,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-05","TRTSDTM":"2020-12-08 01:10:31","TRTEDTM":"2023-12-08 19:10:31","TRT01SDTM":"2020-12-08 01:10:31","TRT01EDTM":"2022-12-08 13:10:31","TRT02SDTM":"2022-12-08 13:10:31","TRT02EDTM":"2023-12-08 19:10:31","AP01SDTM":"2020-12-08 01:10:31","AP01EDTM":"2022-12-08 13:10:31","AP02SDTM":"2022-12-08 13:10:31","AP02EDTM":"2023-12-08 19:10:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-08","EOSDY":1096,"LSTALVDT":"2023-12-25","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7439,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8807,"AVALU":"g/L","BASE2":2.90092,"BASE":3.14085,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02022,"PCHG2":-0.69689,"CHG":-0.26014,"PCHG":-8.28261,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2023-08-06 01:10:31","ADY":971,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-5-id-29","SUBJID":"id-29","SITEID":"RUS-5","AGE":58,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-5","INVNAM":"Dr. RUS-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":2.11508,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-12-05","TRTSDTM":"2020-12-08 01:10:31","TRTEDTM":"2023-12-08 19:10:31","TRT01SDTM":"2020-12-08 01:10:31","TRT01EDTM":"2022-12-08 13:10:31","TRT02SDTM":"2022-12-08 13:10:31","TRT02EDTM":"2023-12-08 19:10:31","AP01SDTM":"2020-12-08 01:10:31","AP01EDTM":"2022-12-08 13:10:31","AP02SDTM":"2022-12-08 13:10:31","AP02EDTM":"2023-12-08 19:10:31","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-12-08","EOSDY":1096,"LSTALVDT":"2023-12-25","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":120,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8618,"AVALU":"g/L","BASE2":2.90092,"BASE":3.14085,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03911,"PCHG2":-1.34833,"CHG":-0.27904,"PCHG":-8.88429,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2023-10-26 01:10:31","ADY":1052,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-6-id-77","SUBJID":"id-77","SITEID":"RUS-6","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-6","INVNAM":"Dr. RUS-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.81259,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-23","TRTSDTM":"2020-11-24 21:11:00","TRTEDTM":"2022-02-14 15:19:45","TRT01SDTM":"2020-11-24 21:11:00","TRT01EDTM":"2021-02-14 09:19:45","TRT02SDTM":"2021-02-14 09:19:45","TRT02EDTM":"2022-02-14 15:19:45","AP01SDTM":"2020-11-24 21:11:00","AP01EDTM":"2021-02-14 09:19:45","AP02SDTM":"2021-02-14 09:19:45","AP02EDTM":"2022-02-14 15:19:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":447,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":495,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7385,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.1891,"AVALU":"U/L","BASE2":1.1891,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-01-11 21:11:00","ADY":48,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-6-id-77","SUBJID":"id-77","SITEID":"RUS-6","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-6","INVNAM":"Dr. RUS-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.81259,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-23","TRTSDTM":"2020-11-24 21:11:00","TRTEDTM":"2022-02-14 15:19:45","TRT01SDTM":"2020-11-24 21:11:00","TRT01EDTM":"2021-02-14 09:19:45","TRT02SDTM":"2021-02-14 09:19:45","TRT02EDTM":"2022-02-14 15:19:45","AP01SDTM":"2020-11-24 21:11:00","AP01EDTM":"2021-02-14 09:19:45","AP02SDTM":"2021-02-14 09:19:45","AP02EDTM":"2022-02-14 15:19:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":447,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":495,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3509,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.10163,"AVALU":"U/L","BASE2":1.1891,"BASE":8.10163,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":6.91253,"PCHG2":581.3255,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-11 21:11:00","ADY":229,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-6-id-77","SUBJID":"id-77","SITEID":"RUS-6","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-6","INVNAM":"Dr. RUS-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.81259,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-23","TRTSDTM":"2020-11-24 21:11:00","TRTEDTM":"2022-02-14 15:19:45","TRT01SDTM":"2020-11-24 21:11:00","TRT01EDTM":"2021-02-14 09:19:45","TRT02SDTM":"2021-02-14 09:19:45","TRT02EDTM":"2022-02-14 15:19:45","AP01SDTM":"2020-11-24 21:11:00","AP01EDTM":"2021-02-14 09:19:45","AP02SDTM":"2021-02-14 09:19:45","AP02EDTM":"2022-02-14 15:19:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":447,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":495,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7926,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.22607,"AVALU":"U/L","BASE2":1.1891,"BASE":8.10163,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":30.03697,"PCHG2":2526.02972,"CHG":23.12444,"PCHG":285.42954,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-03 21:11:00","ADY":283,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-6-id-77","SUBJID":"id-77","SITEID":"RUS-6","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-6","INVNAM":"Dr. RUS-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.81259,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-23","TRTSDTM":"2020-11-24 21:11:00","TRTEDTM":"2022-02-14 15:19:45","TRT01SDTM":"2020-11-24 21:11:00","TRT01EDTM":"2021-02-14 09:19:45","TRT02SDTM":"2021-02-14 09:19:45","TRT02EDTM":"2022-02-14 15:19:45","AP01SDTM":"2020-11-24 21:11:00","AP01EDTM":"2021-02-14 09:19:45","AP02SDTM":"2021-02-14 09:19:45","AP02EDTM":"2022-02-14 15:19:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":447,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":495,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":894,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.94416,"AVALU":"U/L","BASE2":1.1891,"BASE":8.10163,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":20.75506,"PCHG2":1745.4453,"CHG":13.84253,"PCHG":170.86104,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-05 21:11:00","ADY":285,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-6-id-77","SUBJID":"id-77","SITEID":"RUS-6","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-6","INVNAM":"Dr. RUS-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.81259,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-23","TRTSDTM":"2020-11-24 21:11:00","TRTEDTM":"2022-02-14 15:19:45","TRT01SDTM":"2020-11-24 21:11:00","TRT01EDTM":"2021-02-14 09:19:45","TRT02SDTM":"2021-02-14 09:19:45","TRT02EDTM":"2022-02-14 15:19:45","AP01SDTM":"2020-11-24 21:11:00","AP01EDTM":"2021-02-14 09:19:45","AP02SDTM":"2021-02-14 09:19:45","AP02EDTM":"2022-02-14 15:19:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":447,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":495,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1451,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.40091,"AVALU":"U/L","BASE2":1.1891,"BASE":8.10163,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":25.21181,"PCHG2":2120.24653,"CHG":18.29928,"PCHG":225.87163,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-18 21:11:00","ADY":298,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-6-id-77","SUBJID":"id-77","SITEID":"RUS-6","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-6","INVNAM":"Dr. RUS-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.81259,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-23","TRTSDTM":"2020-11-24 21:11:00","TRTEDTM":"2022-02-14 15:19:45","TRT01SDTM":"2020-11-24 21:11:00","TRT01EDTM":"2021-02-14 09:19:45","TRT02SDTM":"2021-02-14 09:19:45","TRT02EDTM":"2022-02-14 15:19:45","AP01SDTM":"2020-11-24 21:11:00","AP01EDTM":"2021-02-14 09:19:45","AP02SDTM":"2021-02-14 09:19:45","AP02EDTM":"2022-02-14 15:19:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":447,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":495,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1122,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.67119,"AVALU":"U/L","BASE2":1.1891,"BASE":8.10163,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.48209,"PCHG2":1133.80811,"CHG":6.56956,"PCHG":81.08938,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-23 21:11:00","ADY":333,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-6-id-77","SUBJID":"id-77","SITEID":"RUS-6","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-6","INVNAM":"Dr. RUS-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.81259,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-23","TRTSDTM":"2020-11-24 21:11:00","TRTEDTM":"2022-02-14 15:19:45","TRT01SDTM":"2020-11-24 21:11:00","TRT01EDTM":"2021-02-14 09:19:45","TRT02SDTM":"2021-02-14 09:19:45","TRT02EDTM":"2022-02-14 15:19:45","AP01SDTM":"2020-11-24 21:11:00","AP01EDTM":"2021-02-14 09:19:45","AP02SDTM":"2021-02-14 09:19:45","AP02EDTM":"2022-02-14 15:19:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":447,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":495,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3990,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.06594,"AVALU":"U/L","BASE2":1.1891,"BASE":8.10163,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":18.87684,"PCHG2":1587.4924,"CHG":11.96431,"PCHG":147.67786,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-17 21:11:00","ADY":419,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-6-id-77","SUBJID":"id-77","SITEID":"RUS-6","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-6","INVNAM":"Dr. RUS-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.81259,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-23","TRTSDTM":"2020-11-24 21:11:00","TRTEDTM":"2022-02-14 15:19:45","TRT01SDTM":"2020-11-24 21:11:00","TRT01EDTM":"2021-02-14 09:19:45","TRT02SDTM":"2021-02-14 09:19:45","TRT02EDTM":"2022-02-14 15:19:45","AP01SDTM":"2020-11-24 21:11:00","AP01EDTM":"2021-02-14 09:19:45","AP02SDTM":"2021-02-14 09:19:45","AP02EDTM":"2022-02-14 15:19:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":447,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":495,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":989,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.09197,"AVALU":"mg/L","BASE2":10.09197,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-01-11 21:11:00","ADY":48,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-6-id-77","SUBJID":"id-77","SITEID":"RUS-6","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-6","INVNAM":"Dr. RUS-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.81259,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-23","TRTSDTM":"2020-11-24 21:11:00","TRTEDTM":"2022-02-14 15:19:45","TRT01SDTM":"2020-11-24 21:11:00","TRT01EDTM":"2021-02-14 09:19:45","TRT02SDTM":"2021-02-14 09:19:45","TRT02EDTM":"2022-02-14 15:19:45","AP01SDTM":"2020-11-24 21:11:00","AP01EDTM":"2021-02-14 09:19:45","AP02SDTM":"2021-02-14 09:19:45","AP02EDTM":"2022-02-14 15:19:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":447,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":495,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6392,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.06257,"AVALU":"mg/L","BASE2":10.09197,"BASE":8.06257,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.0294,"PCHG2":-20.10909,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-11 21:11:00","ADY":229,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-6-id-77","SUBJID":"id-77","SITEID":"RUS-6","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-6","INVNAM":"Dr. RUS-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.81259,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-23","TRTSDTM":"2020-11-24 21:11:00","TRTEDTM":"2022-02-14 15:19:45","TRT01SDTM":"2020-11-24 21:11:00","TRT01EDTM":"2021-02-14 09:19:45","TRT02SDTM":"2021-02-14 09:19:45","TRT02EDTM":"2022-02-14 15:19:45","AP01SDTM":"2020-11-24 21:11:00","AP01EDTM":"2021-02-14 09:19:45","AP02SDTM":"2021-02-14 09:19:45","AP02EDTM":"2022-02-14 15:19:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":447,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":495,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7029,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.10278,"AVALU":"mg/L","BASE2":10.09197,"BASE":8.06257,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01081,"PCHG2":0.1071,"CHG":2.04021,"PCHG":25.30474,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-09-03 21:11:00","ADY":283,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-6-id-77","SUBJID":"id-77","SITEID":"RUS-6","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-6","INVNAM":"Dr. RUS-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.81259,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-23","TRTSDTM":"2020-11-24 21:11:00","TRTEDTM":"2022-02-14 15:19:45","TRT01SDTM":"2020-11-24 21:11:00","TRT01EDTM":"2021-02-14 09:19:45","TRT02SDTM":"2021-02-14 09:19:45","TRT02EDTM":"2022-02-14 15:19:45","AP01SDTM":"2020-11-24 21:11:00","AP01EDTM":"2021-02-14 09:19:45","AP02SDTM":"2021-02-14 09:19:45","AP02EDTM":"2022-02-14 15:19:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":447,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":495,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6530,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.48825,"AVALU":"mg/L","BASE2":10.09197,"BASE":8.06257,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.60372,"PCHG2":-15.89107,"CHG":0.42568,"PCHG":5.27972,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-05 21:11:00","ADY":285,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-6-id-77","SUBJID":"id-77","SITEID":"RUS-6","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-6","INVNAM":"Dr. RUS-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.81259,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-23","TRTSDTM":"2020-11-24 21:11:00","TRTEDTM":"2022-02-14 15:19:45","TRT01SDTM":"2020-11-24 21:11:00","TRT01EDTM":"2021-02-14 09:19:45","TRT02SDTM":"2021-02-14 09:19:45","TRT02EDTM":"2022-02-14 15:19:45","AP01SDTM":"2020-11-24 21:11:00","AP01EDTM":"2021-02-14 09:19:45","AP02SDTM":"2021-02-14 09:19:45","AP02EDTM":"2022-02-14 15:19:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":447,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":495,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3421,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.87535,"AVALU":"mg/L","BASE2":10.09197,"BASE":8.06257,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.21663,"PCHG2":-12.05538,"CHG":0.81278,"PCHG":10.08089,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-18 21:11:00","ADY":298,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-6-id-77","SUBJID":"id-77","SITEID":"RUS-6","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-6","INVNAM":"Dr. RUS-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.81259,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-23","TRTSDTM":"2020-11-24 21:11:00","TRTEDTM":"2022-02-14 15:19:45","TRT01SDTM":"2020-11-24 21:11:00","TRT01EDTM":"2021-02-14 09:19:45","TRT02SDTM":"2021-02-14 09:19:45","TRT02EDTM":"2022-02-14 15:19:45","AP01SDTM":"2020-11-24 21:11:00","AP01EDTM":"2021-02-14 09:19:45","AP02SDTM":"2021-02-14 09:19:45","AP02EDTM":"2022-02-14 15:19:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":447,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":495,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7080,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.29003,"AVALU":"mg/L","BASE2":10.09197,"BASE":8.06257,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.80194,"PCHG2":-17.85517,"CHG":0.22746,"PCHG":2.82124,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-23 21:11:00","ADY":333,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-6-id-77","SUBJID":"id-77","SITEID":"RUS-6","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-6","INVNAM":"Dr. RUS-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.81259,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-23","TRTSDTM":"2020-11-24 21:11:00","TRTEDTM":"2022-02-14 15:19:45","TRT01SDTM":"2020-11-24 21:11:00","TRT01EDTM":"2021-02-14 09:19:45","TRT02SDTM":"2021-02-14 09:19:45","TRT02EDTM":"2022-02-14 15:19:45","AP01SDTM":"2020-11-24 21:11:00","AP01EDTM":"2021-02-14 09:19:45","AP02SDTM":"2021-02-14 09:19:45","AP02EDTM":"2022-02-14 15:19:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":447,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":495,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":875,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.14431,"AVALU":"mg/L","BASE2":10.09197,"BASE":8.06257,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.94766,"PCHG2":-9.39026,"CHG":1.08174,"PCHG":13.41683,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-17 21:11:00","ADY":419,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-6-id-77","SUBJID":"id-77","SITEID":"RUS-6","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-6","INVNAM":"Dr. RUS-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.81259,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-23","TRTSDTM":"2020-11-24 21:11:00","TRTEDTM":"2022-02-14 15:19:45","TRT01SDTM":"2020-11-24 21:11:00","TRT01EDTM":"2021-02-14 09:19:45","TRT02SDTM":"2021-02-14 09:19:45","TRT02EDTM":"2022-02-14 15:19:45","AP01SDTM":"2020-11-24 21:11:00","AP01EDTM":"2021-02-14 09:19:45","AP02SDTM":"2021-02-14 09:19:45","AP02EDTM":"2022-02-14 15:19:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":447,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":495,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5485,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97121,"AVALU":"g/L","BASE2":2.97121,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-11 21:11:00","ADY":48,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-6-id-77","SUBJID":"id-77","SITEID":"RUS-6","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-6","INVNAM":"Dr. RUS-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.81259,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-23","TRTSDTM":"2020-11-24 21:11:00","TRTEDTM":"2022-02-14 15:19:45","TRT01SDTM":"2020-11-24 21:11:00","TRT01EDTM":"2021-02-14 09:19:45","TRT02SDTM":"2021-02-14 09:19:45","TRT02EDTM":"2022-02-14 15:19:45","AP01SDTM":"2020-11-24 21:11:00","AP01EDTM":"2021-02-14 09:19:45","AP02SDTM":"2021-02-14 09:19:45","AP02EDTM":"2022-02-14 15:19:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":447,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":495,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2533,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88602,"AVALU":"g/L","BASE2":2.97121,"BASE":2.88602,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.08519,"PCHG2":-2.8673,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-11 21:11:00","ADY":229,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-6-id-77","SUBJID":"id-77","SITEID":"RUS-6","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-6","INVNAM":"Dr. RUS-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.81259,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-23","TRTSDTM":"2020-11-24 21:11:00","TRTEDTM":"2022-02-14 15:19:45","TRT01SDTM":"2020-11-24 21:11:00","TRT01EDTM":"2021-02-14 09:19:45","TRT02SDTM":"2021-02-14 09:19:45","TRT02EDTM":"2022-02-14 15:19:45","AP01SDTM":"2020-11-24 21:11:00","AP01EDTM":"2021-02-14 09:19:45","AP02SDTM":"2021-02-14 09:19:45","AP02EDTM":"2022-02-14 15:19:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":447,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":495,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4602,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96202,"AVALU":"g/L","BASE2":2.97121,"BASE":2.88602,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0092,"PCHG2":-0.3095,"CHG":0.076,"PCHG":2.6333,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-03 21:11:00","ADY":283,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-6-id-77","SUBJID":"id-77","SITEID":"RUS-6","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-6","INVNAM":"Dr. RUS-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.81259,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-23","TRTSDTM":"2020-11-24 21:11:00","TRTEDTM":"2022-02-14 15:19:45","TRT01SDTM":"2020-11-24 21:11:00","TRT01EDTM":"2021-02-14 09:19:45","TRT02SDTM":"2021-02-14 09:19:45","TRT02EDTM":"2022-02-14 15:19:45","AP01SDTM":"2020-11-24 21:11:00","AP01EDTM":"2021-02-14 09:19:45","AP02SDTM":"2021-02-14 09:19:45","AP02EDTM":"2022-02-14 15:19:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":447,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":495,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4096,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87157,"AVALU":"g/L","BASE2":2.97121,"BASE":2.88602,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09964,"PCHG2":-3.35362,"CHG":-0.01445,"PCHG":-0.50068,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-05 21:11:00","ADY":285,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-6-id-77","SUBJID":"id-77","SITEID":"RUS-6","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-6","INVNAM":"Dr. RUS-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.81259,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-23","TRTSDTM":"2020-11-24 21:11:00","TRTEDTM":"2022-02-14 15:19:45","TRT01SDTM":"2020-11-24 21:11:00","TRT01EDTM":"2021-02-14 09:19:45","TRT02SDTM":"2021-02-14 09:19:45","TRT02EDTM":"2022-02-14 15:19:45","AP01SDTM":"2020-11-24 21:11:00","AP01EDTM":"2021-02-14 09:19:45","AP02SDTM":"2021-02-14 09:19:45","AP02EDTM":"2022-02-14 15:19:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":447,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":495,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5647,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95935,"AVALU":"g/L","BASE2":2.97121,"BASE":2.88602,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01186,"PCHG2":-0.39913,"CHG":0.07333,"PCHG":2.54102,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-18 21:11:00","ADY":298,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-6-id-77","SUBJID":"id-77","SITEID":"RUS-6","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-6","INVNAM":"Dr. RUS-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.81259,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-23","TRTSDTM":"2020-11-24 21:11:00","TRTEDTM":"2022-02-14 15:19:45","TRT01SDTM":"2020-11-24 21:11:00","TRT01EDTM":"2021-02-14 09:19:45","TRT02SDTM":"2021-02-14 09:19:45","TRT02EDTM":"2022-02-14 15:19:45","AP01SDTM":"2020-11-24 21:11:00","AP01EDTM":"2021-02-14 09:19:45","AP02SDTM":"2021-02-14 09:19:45","AP02EDTM":"2022-02-14 15:19:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":447,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":495,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2288,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75833,"AVALU":"g/L","BASE2":2.97121,"BASE":2.88602,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21288,"PCHG2":-7.16478,"CHG":-0.12769,"PCHG":-4.42434,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-23 21:11:00","ADY":333,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-6-id-77","SUBJID":"id-77","SITEID":"RUS-6","AGE":26,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"Y","INVID":"INV ID RUS-6","INVNAM":"Dr. RUS-6 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"Eurasia","STRATA1":"B","STRATA2":"S2","BMRKR1":5.81259,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-23","TRTSDTM":"2020-11-24 21:11:00","TRTEDTM":"2022-02-14 15:19:45","TRT01SDTM":"2020-11-24 21:11:00","TRT01EDTM":"2021-02-14 09:19:45","TRT02SDTM":"2021-02-14 09:19:45","TRT02EDTM":"2022-02-14 15:19:45","AP01SDTM":"2020-11-24 21:11:00","AP01EDTM":"2021-02-14 09:19:45","AP02SDTM":"2021-02-14 09:19:45","AP02EDTM":"2022-02-14 15:19:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":447,"DCSREAS":"DEATH","DTHDT":"2022-04-04","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":49,"LDDTHGR1":">30","LSTALVDT":"2022-04-04","DTHADY":495,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4317,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97368,"AVALU":"g/L","BASE2":2.97121,"BASE":2.88602,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00246,"PCHG2":0.08288,"CHG":0.08766,"PCHG":3.03726,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-17 21:11:00","ADY":419,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-7-id-243","SUBJID":"id-243","SITEID":"RUS-7","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-7","INVNAM":"Dr. RUS-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.0318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-22","TRTSDTM":"2021-01-23 08:04:50","TRTEDTM":"2022-02-13 14:12:56","TRT01SDTM":"2021-01-23 08:04:50","TRT01EDTM":"2021-02-13 08:12:56","TRT02SDTM":"2021-02-13 08:12:56","TRT02EDTM":"2022-02-13 14:12:56","AP01SDTM":"2021-01-23 08:04:50","AP01EDTM":"2021-02-13 08:12:56","AP02SDTM":"2021-02-13 08:12:56","AP02EDTM":"2022-02-13 14:12:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":387,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-24","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2386,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.24004,"AVALU":"U/L","BASE2":31.24004,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-31 08:04:50","ADY":8,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-7-id-243","SUBJID":"id-243","SITEID":"RUS-7","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-7","INVNAM":"Dr. RUS-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.0318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-22","TRTSDTM":"2021-01-23 08:04:50","TRTEDTM":"2022-02-13 14:12:56","TRT01SDTM":"2021-01-23 08:04:50","TRT01EDTM":"2021-02-13 08:12:56","TRT02SDTM":"2021-02-13 08:12:56","TRT02EDTM":"2022-02-13 14:12:56","AP01SDTM":"2021-01-23 08:04:50","AP01EDTM":"2021-02-13 08:12:56","AP02SDTM":"2021-02-13 08:12:56","AP02EDTM":"2022-02-13 14:12:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":387,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-24","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6385,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.73835,"AVALU":"U/L","BASE2":31.24004,"BASE":11.73835,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-19.50169,"PCHG2":-62.42531,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-06 08:04:50","ADY":14,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-7-id-243","SUBJID":"id-243","SITEID":"RUS-7","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-7","INVNAM":"Dr. RUS-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.0318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-22","TRTSDTM":"2021-01-23 08:04:50","TRTEDTM":"2022-02-13 14:12:56","TRT01SDTM":"2021-01-23 08:04:50","TRT01EDTM":"2021-02-13 08:12:56","TRT02SDTM":"2021-02-13 08:12:56","TRT02EDTM":"2022-02-13 14:12:56","AP01SDTM":"2021-01-23 08:04:50","AP01EDTM":"2021-02-13 08:12:56","AP02SDTM":"2021-02-13 08:12:56","AP02EDTM":"2022-02-13 14:12:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":387,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-24","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":507,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.43373,"AVALU":"U/L","BASE2":31.24004,"BASE":11.73835,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-24.80632,"PCHG2":-79.40551,"CHG":-5.30462,"PCHG":-45.19053,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-03-09 08:04:50","ADY":45,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-7-id-243","SUBJID":"id-243","SITEID":"RUS-7","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-7","INVNAM":"Dr. RUS-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.0318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-22","TRTSDTM":"2021-01-23 08:04:50","TRTEDTM":"2022-02-13 14:12:56","TRT01SDTM":"2021-01-23 08:04:50","TRT01EDTM":"2021-02-13 08:12:56","TRT02SDTM":"2021-02-13 08:12:56","TRT02EDTM":"2022-02-13 14:12:56","AP01SDTM":"2021-01-23 08:04:50","AP01EDTM":"2021-02-13 08:12:56","AP02SDTM":"2021-02-13 08:12:56","AP02EDTM":"2022-02-13 14:12:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":387,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-24","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4428,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.24878,"AVALU":"U/L","BASE2":31.24004,"BASE":11.73835,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.99126,"PCHG2":-15.97712,"CHG":14.51044,"PCHG":123.61563,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-04 08:04:50","ADY":224,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-7-id-243","SUBJID":"id-243","SITEID":"RUS-7","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-7","INVNAM":"Dr. RUS-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.0318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-22","TRTSDTM":"2021-01-23 08:04:50","TRTEDTM":"2022-02-13 14:12:56","TRT01SDTM":"2021-01-23 08:04:50","TRT01EDTM":"2021-02-13 08:12:56","TRT02SDTM":"2021-02-13 08:12:56","TRT02EDTM":"2022-02-13 14:12:56","AP01SDTM":"2021-01-23 08:04:50","AP01EDTM":"2021-02-13 08:12:56","AP02SDTM":"2021-02-13 08:12:56","AP02EDTM":"2022-02-13 14:12:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":387,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-24","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5639,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.7628,"AVALU":"U/L","BASE2":31.24004,"BASE":11.73835,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.47725,"PCHG2":-17.53278,"CHG":14.02445,"PCHG":119.47544,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-06 08:04:50","ADY":226,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-7-id-243","SUBJID":"id-243","SITEID":"RUS-7","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-7","INVNAM":"Dr. RUS-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.0318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-22","TRTSDTM":"2021-01-23 08:04:50","TRTEDTM":"2022-02-13 14:12:56","TRT01SDTM":"2021-01-23 08:04:50","TRT01EDTM":"2021-02-13 08:12:56","TRT02SDTM":"2021-02-13 08:12:56","TRT02EDTM":"2022-02-13 14:12:56","AP01SDTM":"2021-01-23 08:04:50","AP01EDTM":"2021-02-13 08:12:56","AP02SDTM":"2021-02-13 08:12:56","AP02EDTM":"2022-02-13 14:12:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":387,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-24","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2642,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.04048,"AVALU":"U/L","BASE2":31.24004,"BASE":11.73835,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.19956,"PCHG2":-35.85002,"CHG":8.30213,"PCHG":70.72657,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-06 08:04:50","ADY":317,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-7-id-243","SUBJID":"id-243","SITEID":"RUS-7","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-7","INVNAM":"Dr. RUS-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.0318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-22","TRTSDTM":"2021-01-23 08:04:50","TRTEDTM":"2022-02-13 14:12:56","TRT01SDTM":"2021-01-23 08:04:50","TRT01EDTM":"2021-02-13 08:12:56","TRT02SDTM":"2021-02-13 08:12:56","TRT02EDTM":"2022-02-13 14:12:56","AP01SDTM":"2021-01-23 08:04:50","AP01EDTM":"2021-02-13 08:12:56","AP02SDTM":"2021-02-13 08:12:56","AP02EDTM":"2022-02-13 14:12:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":387,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-24","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5867,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.04378,"AVALU":"U/L","BASE2":31.24004,"BASE":11.73835,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.19626,"PCHG2":-32.63844,"CHG":9.30543,"PCHG":79.27375,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-27 08:04:50","ADY":338,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-7-id-243","SUBJID":"id-243","SITEID":"RUS-7","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-7","INVNAM":"Dr. RUS-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.0318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-22","TRTSDTM":"2021-01-23 08:04:50","TRTEDTM":"2022-02-13 14:12:56","TRT01SDTM":"2021-01-23 08:04:50","TRT01EDTM":"2021-02-13 08:12:56","TRT02SDTM":"2021-02-13 08:12:56","TRT02EDTM":"2022-02-13 14:12:56","AP01SDTM":"2021-01-23 08:04:50","AP01EDTM":"2021-02-13 08:12:56","AP02SDTM":"2021-02-13 08:12:56","AP02EDTM":"2022-02-13 14:12:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":387,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-24","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7472,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.96018,"AVALU":"mg/L","BASE2":9.96018,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-31 08:04:50","ADY":8,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-7-id-243","SUBJID":"id-243","SITEID":"RUS-7","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-7","INVNAM":"Dr. RUS-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.0318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-22","TRTSDTM":"2021-01-23 08:04:50","TRTEDTM":"2022-02-13 14:12:56","TRT01SDTM":"2021-01-23 08:04:50","TRT01EDTM":"2021-02-13 08:12:56","TRT02SDTM":"2021-02-13 08:12:56","TRT02EDTM":"2022-02-13 14:12:56","AP01SDTM":"2021-01-23 08:04:50","AP01EDTM":"2021-02-13 08:12:56","AP02SDTM":"2021-02-13 08:12:56","AP02EDTM":"2022-02-13 14:12:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":387,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-24","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4798,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.00951,"AVALU":"mg/L","BASE2":9.96018,"BASE":8.00951,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.95067,"PCHG2":-19.58469,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-06 08:04:50","ADY":14,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-7-id-243","SUBJID":"id-243","SITEID":"RUS-7","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-7","INVNAM":"Dr. RUS-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.0318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-22","TRTSDTM":"2021-01-23 08:04:50","TRTEDTM":"2022-02-13 14:12:56","TRT01SDTM":"2021-01-23 08:04:50","TRT01EDTM":"2021-02-13 08:12:56","TRT02SDTM":"2021-02-13 08:12:56","TRT02EDTM":"2022-02-13 14:12:56","AP01SDTM":"2021-01-23 08:04:50","AP01EDTM":"2021-02-13 08:12:56","AP02SDTM":"2021-02-13 08:12:56","AP02EDTM":"2022-02-13 14:12:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":387,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-24","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3897,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.39412,"AVALU":"mg/L","BASE2":9.96018,"BASE":8.00951,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.56606,"PCHG2":-25.76322,"CHG":-0.61539,"PCHG":-7.68328,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-03-09 08:04:50","ADY":45,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-7-id-243","SUBJID":"id-243","SITEID":"RUS-7","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-7","INVNAM":"Dr. RUS-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.0318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-22","TRTSDTM":"2021-01-23 08:04:50","TRTEDTM":"2022-02-13 14:12:56","TRT01SDTM":"2021-01-23 08:04:50","TRT01EDTM":"2021-02-13 08:12:56","TRT02SDTM":"2021-02-13 08:12:56","TRT02EDTM":"2022-02-13 14:12:56","AP01SDTM":"2021-01-23 08:04:50","AP01EDTM":"2021-02-13 08:12:56","AP02SDTM":"2021-02-13 08:12:56","AP02EDTM":"2022-02-13 14:12:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":387,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-24","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2664,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.39569,"AVALU":"mg/L","BASE2":9.96018,"BASE":8.00951,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.5645,"PCHG2":-5.66756,"CHG":1.38617,"PCHG":17.30657,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-04 08:04:50","ADY":224,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-7-id-243","SUBJID":"id-243","SITEID":"RUS-7","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-7","INVNAM":"Dr. RUS-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.0318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-22","TRTSDTM":"2021-01-23 08:04:50","TRTEDTM":"2022-02-13 14:12:56","TRT01SDTM":"2021-01-23 08:04:50","TRT01EDTM":"2021-02-13 08:12:56","TRT02SDTM":"2021-02-13 08:12:56","TRT02EDTM":"2022-02-13 14:12:56","AP01SDTM":"2021-01-23 08:04:50","AP01EDTM":"2021-02-13 08:12:56","AP02SDTM":"2021-02-13 08:12:56","AP02EDTM":"2022-02-13 14:12:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":387,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-24","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":977,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.31665,"AVALU":"mg/L","BASE2":9.96018,"BASE":8.00951,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.64353,"PCHG2":-6.46104,"CHG":1.30714,"PCHG":16.31984,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-06 08:04:50","ADY":226,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-7-id-243","SUBJID":"id-243","SITEID":"RUS-7","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-7","INVNAM":"Dr. RUS-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.0318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-22","TRTSDTM":"2021-01-23 08:04:50","TRTEDTM":"2022-02-13 14:12:56","TRT01SDTM":"2021-01-23 08:04:50","TRT01EDTM":"2021-02-13 08:12:56","TRT02SDTM":"2021-02-13 08:12:56","TRT02EDTM":"2022-02-13 14:12:56","AP01SDTM":"2021-01-23 08:04:50","AP01EDTM":"2021-02-13 08:12:56","AP02SDTM":"2021-02-13 08:12:56","AP02EDTM":"2022-02-13 14:12:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":387,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-24","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7693,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.50697,"AVALU":"mg/L","BASE2":9.96018,"BASE":8.00951,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.45321,"PCHG2":-14.59019,"CHG":0.49746,"PCHG":6.21088,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-06 08:04:50","ADY":317,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-7-id-243","SUBJID":"id-243","SITEID":"RUS-7","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-7","INVNAM":"Dr. RUS-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.0318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-22","TRTSDTM":"2021-01-23 08:04:50","TRTEDTM":"2022-02-13 14:12:56","TRT01SDTM":"2021-01-23 08:04:50","TRT01EDTM":"2021-02-13 08:12:56","TRT02SDTM":"2021-02-13 08:12:56","TRT02EDTM":"2022-02-13 14:12:56","AP01SDTM":"2021-01-23 08:04:50","AP01EDTM":"2021-02-13 08:12:56","AP02SDTM":"2021-02-13 08:12:56","AP02EDTM":"2022-02-13 14:12:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":387,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-24","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":56,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.43485,"AVALU":"mg/L","BASE2":9.96018,"BASE":8.00951,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.52533,"PCHG2":-5.27435,"CHG":1.42534,"PCHG":17.79554,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-27 08:04:50","ADY":338,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-7-id-243","SUBJID":"id-243","SITEID":"RUS-7","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-7","INVNAM":"Dr. RUS-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.0318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-22","TRTSDTM":"2021-01-23 08:04:50","TRTEDTM":"2022-02-13 14:12:56","TRT01SDTM":"2021-01-23 08:04:50","TRT01EDTM":"2021-02-13 08:12:56","TRT02SDTM":"2021-02-13 08:12:56","TRT02EDTM":"2022-02-13 14:12:56","AP01SDTM":"2021-01-23 08:04:50","AP01EDTM":"2021-02-13 08:12:56","AP02SDTM":"2021-02-13 08:12:56","AP02EDTM":"2022-02-13 14:12:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":387,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-24","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3906,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83117,"AVALU":"g/L","BASE2":2.83117,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-31 08:04:50","ADY":8,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-7-id-243","SUBJID":"id-243","SITEID":"RUS-7","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-7","INVNAM":"Dr. RUS-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.0318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-22","TRTSDTM":"2021-01-23 08:04:50","TRTEDTM":"2022-02-13 14:12:56","TRT01SDTM":"2021-01-23 08:04:50","TRT01EDTM":"2021-02-13 08:12:56","TRT02SDTM":"2021-02-13 08:12:56","TRT02EDTM":"2022-02-13 14:12:56","AP01SDTM":"2021-01-23 08:04:50","AP01EDTM":"2021-02-13 08:12:56","AP02SDTM":"2021-02-13 08:12:56","AP02EDTM":"2022-02-13 14:12:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":387,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-24","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7055,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80818,"AVALU":"g/L","BASE2":2.83117,"BASE":2.80818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.02298,"PCHG2":-0.81172,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-06 08:04:50","ADY":14,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-7-id-243","SUBJID":"id-243","SITEID":"RUS-7","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-7","INVNAM":"Dr. RUS-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.0318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-22","TRTSDTM":"2021-01-23 08:04:50","TRTEDTM":"2022-02-13 14:12:56","TRT01SDTM":"2021-01-23 08:04:50","TRT01EDTM":"2021-02-13 08:12:56","TRT02SDTM":"2021-02-13 08:12:56","TRT02EDTM":"2022-02-13 14:12:56","AP01SDTM":"2021-01-23 08:04:50","AP01EDTM":"2021-02-13 08:12:56","AP02SDTM":"2021-02-13 08:12:56","AP02EDTM":"2022-02-13 14:12:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":387,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-24","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4081,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00369,"AVALU":"g/L","BASE2":2.83117,"BASE":2.80818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17252,"PCHG2":6.09368,"CHG":0.1955,"PCHG":6.96191,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2021-03-09 08:04:50","ADY":45,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-7-id-243","SUBJID":"id-243","SITEID":"RUS-7","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-7","INVNAM":"Dr. RUS-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.0318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-22","TRTSDTM":"2021-01-23 08:04:50","TRTEDTM":"2022-02-13 14:12:56","TRT01SDTM":"2021-01-23 08:04:50","TRT01EDTM":"2021-02-13 08:12:56","TRT02SDTM":"2021-02-13 08:12:56","TRT02EDTM":"2022-02-13 14:12:56","AP01SDTM":"2021-01-23 08:04:50","AP01EDTM":"2021-02-13 08:12:56","AP02SDTM":"2021-02-13 08:12:56","AP02EDTM":"2022-02-13 14:12:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":387,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-24","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5317,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98309,"AVALU":"g/L","BASE2":2.83117,"BASE":2.80818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15192,"PCHG2":5.36609,"CHG":0.1749,"PCHG":6.22837,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-04 08:04:50","ADY":224,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-7-id-243","SUBJID":"id-243","SITEID":"RUS-7","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-7","INVNAM":"Dr. RUS-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.0318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-22","TRTSDTM":"2021-01-23 08:04:50","TRTEDTM":"2022-02-13 14:12:56","TRT01SDTM":"2021-01-23 08:04:50","TRT01EDTM":"2021-02-13 08:12:56","TRT02SDTM":"2021-02-13 08:12:56","TRT02EDTM":"2022-02-13 14:12:56","AP01SDTM":"2021-01-23 08:04:50","AP01EDTM":"2021-02-13 08:12:56","AP02SDTM":"2021-02-13 08:12:56","AP02EDTM":"2022-02-13 14:12:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":387,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-24","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6337,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87199,"AVALU":"g/L","BASE2":2.83117,"BASE":2.80818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04082,"PCHG2":1.4418,"CHG":0.0638,"PCHG":2.27197,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-06 08:04:50","ADY":226,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-7-id-243","SUBJID":"id-243","SITEID":"RUS-7","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-7","INVNAM":"Dr. RUS-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.0318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-22","TRTSDTM":"2021-01-23 08:04:50","TRTEDTM":"2022-02-13 14:12:56","TRT01SDTM":"2021-01-23 08:04:50","TRT01EDTM":"2021-02-13 08:12:56","TRT02SDTM":"2021-02-13 08:12:56","TRT02EDTM":"2022-02-13 14:12:56","AP01SDTM":"2021-01-23 08:04:50","AP01EDTM":"2021-02-13 08:12:56","AP02SDTM":"2021-02-13 08:12:56","AP02EDTM":"2022-02-13 14:12:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":387,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-24","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3443,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94271,"AVALU":"g/L","BASE2":2.83117,"BASE":2.80818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11155,"PCHG2":3.93991,"CHG":0.13453,"PCHG":4.79052,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-06 08:04:50","ADY":317,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-RUS-7-id-243","SUBJID":"id-243","SITEID":"RUS-7","AGE":27,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"RUS","DTHFL":"N","INVID":"INV ID RUS-7","INVNAM":"Dr. RUS-7 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"Eurasia","STRATA1":"C","STRATA2":"S2","BMRKR1":3.0318,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2021-01-22","TRTSDTM":"2021-01-23 08:04:50","TRTEDTM":"2022-02-13 14:12:56","TRT01SDTM":"2021-01-23 08:04:50","TRT01EDTM":"2021-02-13 08:12:56","TRT02SDTM":"2021-02-13 08:12:56","TRT02EDTM":"2022-02-13 14:12:56","AP01SDTM":"2021-01-23 08:04:50","AP01EDTM":"2021-02-13 08:12:56","AP02SDTM":"2021-02-13 08:12:56","AP02EDTM":"2022-02-13 14:12:56","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":387,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-02-24","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4832,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.06747,"AVALU":"g/L","BASE2":2.83117,"BASE":2.80818,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.2363,"PCHG2":8.3465,"CHG":0.25928,"PCHG":9.23317,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2021-12-27 08:04:50","ADY":338,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-137","SUBJID":"id-137","SITEID":"USA-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":3.40697,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-03 19:18:43","TRTEDTM":"2022-05-03 13:18:43","TRT01SDTM":"2019-05-03 19:18:43","TRT01EDTM":"2021-05-03 07:18:43","TRT02SDTM":"2021-05-03 07:18:43","TRT02EDTM":"2022-05-03 13:18:43","AP01SDTM":"2019-05-03 19:18:43","AP01EDTM":"2021-05-03 07:18:43","AP02SDTM":"2021-05-03 07:18:43","AP02EDTM":"2022-05-03 13:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-19","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":879,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.0571,"AVALU":"U/L","BASE2":14.0571,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-06-03 19:18:43","ADY":31,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-137","SUBJID":"id-137","SITEID":"USA-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":3.40697,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-03 19:18:43","TRTEDTM":"2022-05-03 13:18:43","TRT01SDTM":"2019-05-03 19:18:43","TRT01EDTM":"2021-05-03 07:18:43","TRT02SDTM":"2021-05-03 07:18:43","TRT02EDTM":"2022-05-03 13:18:43","AP01SDTM":"2019-05-03 19:18:43","AP01EDTM":"2021-05-03 07:18:43","AP02SDTM":"2021-05-03 07:18:43","AP02EDTM":"2022-05-03 13:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-19","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4402,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.18845,"AVALU":"U/L","BASE2":14.0571,"BASE":19.18845,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":5.13135,"PCHG2":36.50361,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-02 19:18:43","ADY":91,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-137","SUBJID":"id-137","SITEID":"USA-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":3.40697,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-03 19:18:43","TRTEDTM":"2022-05-03 13:18:43","TRT01SDTM":"2019-05-03 19:18:43","TRT01EDTM":"2021-05-03 07:18:43","TRT02SDTM":"2021-05-03 07:18:43","TRT02EDTM":"2022-05-03 13:18:43","AP01SDTM":"2019-05-03 19:18:43","AP01EDTM":"2021-05-03 07:18:43","AP02SDTM":"2021-05-03 07:18:43","AP02EDTM":"2022-05-03 13:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-19","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8010,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.54982,"AVALU":"U/L","BASE2":14.0571,"BASE":19.18845,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.49272,"PCHG2":10.61898,"CHG":-3.63863,"PCHG":-18.9626,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-20 19:18:43","ADY":140,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-137","SUBJID":"id-137","SITEID":"USA-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":3.40697,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-03 19:18:43","TRTEDTM":"2022-05-03 13:18:43","TRT01SDTM":"2019-05-03 19:18:43","TRT01EDTM":"2021-05-03 07:18:43","TRT02SDTM":"2021-05-03 07:18:43","TRT02EDTM":"2022-05-03 13:18:43","AP01SDTM":"2019-05-03 19:18:43","AP01EDTM":"2021-05-03 07:18:43","AP02SDTM":"2021-05-03 07:18:43","AP02EDTM":"2022-05-03 13:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-19","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5664,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.45185,"AVALU":"U/L","BASE2":14.0571,"BASE":19.18845,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.60525,"PCHG2":-18.53331,"CHG":-7.7366,"PCHG":-40.31903,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-01 19:18:43","ADY":395,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-137","SUBJID":"id-137","SITEID":"USA-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":3.40697,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-03 19:18:43","TRTEDTM":"2022-05-03 13:18:43","TRT01SDTM":"2019-05-03 19:18:43","TRT01EDTM":"2021-05-03 07:18:43","TRT02SDTM":"2021-05-03 07:18:43","TRT02EDTM":"2022-05-03 13:18:43","AP01SDTM":"2019-05-03 19:18:43","AP01EDTM":"2021-05-03 07:18:43","AP02SDTM":"2021-05-03 07:18:43","AP02EDTM":"2022-05-03 13:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-19","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1329,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.51137,"AVALU":"U/L","BASE2":14.0571,"BASE":19.18845,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.45427,"PCHG2":17.4593,"CHG":-2.67708,"PCHG":-13.95151,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-18 19:18:43","ADY":777,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-137","SUBJID":"id-137","SITEID":"USA-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":3.40697,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-03 19:18:43","TRTEDTM":"2022-05-03 13:18:43","TRT01SDTM":"2019-05-03 19:18:43","TRT01EDTM":"2021-05-03 07:18:43","TRT02SDTM":"2021-05-03 07:18:43","TRT02EDTM":"2022-05-03 13:18:43","AP01SDTM":"2019-05-03 19:18:43","AP01EDTM":"2021-05-03 07:18:43","AP02SDTM":"2021-05-03 07:18:43","AP02EDTM":"2022-05-03 13:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-19","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4360,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.16985,"AVALU":"U/L","BASE2":14.0571,"BASE":19.18845,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.11275,"PCHG2":71.94052,"CHG":4.9814,"PCHG":25.96042,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-01 19:18:43","ADY":1033,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-137","SUBJID":"id-137","SITEID":"USA-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":3.40697,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-03 19:18:43","TRTEDTM":"2022-05-03 13:18:43","TRT01SDTM":"2019-05-03 19:18:43","TRT01EDTM":"2021-05-03 07:18:43","TRT02SDTM":"2021-05-03 07:18:43","TRT02EDTM":"2022-05-03 13:18:43","AP01SDTM":"2019-05-03 19:18:43","AP01EDTM":"2021-05-03 07:18:43","AP02SDTM":"2021-05-03 07:18:43","AP02EDTM":"2022-05-03 13:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-19","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5740,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.84728,"AVALU":"U/L","BASE2":14.0571,"BASE":19.18845,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.20983,"PCHG2":-37.06188,"CHG":-10.34118,"PCHG":-53.89271,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-03 19:18:43","ADY":1035,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-137","SUBJID":"id-137","SITEID":"USA-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":3.40697,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-03 19:18:43","TRTEDTM":"2022-05-03 13:18:43","TRT01SDTM":"2019-05-03 19:18:43","TRT01EDTM":"2021-05-03 07:18:43","TRT02SDTM":"2021-05-03 07:18:43","TRT02EDTM":"2022-05-03 13:18:43","AP01SDTM":"2019-05-03 19:18:43","AP01EDTM":"2021-05-03 07:18:43","AP02SDTM":"2021-05-03 07:18:43","AP02EDTM":"2022-05-03 13:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-19","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4046,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.51252,"AVALU":"mg/L","BASE2":6.51252,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2019-06-03 19:18:43","ADY":31,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-137","SUBJID":"id-137","SITEID":"USA-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":3.40697,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-03 19:18:43","TRTEDTM":"2022-05-03 13:18:43","TRT01SDTM":"2019-05-03 19:18:43","TRT01EDTM":"2021-05-03 07:18:43","TRT02SDTM":"2021-05-03 07:18:43","TRT02EDTM":"2022-05-03 13:18:43","AP01SDTM":"2019-05-03 19:18:43","AP01EDTM":"2021-05-03 07:18:43","AP02SDTM":"2021-05-03 07:18:43","AP02EDTM":"2022-05-03 13:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-19","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1885,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.36761,"AVALU":"mg/L","BASE2":6.51252,"BASE":9.36761,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.8551,"PCHG2":43.84016,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-02 19:18:43","ADY":91,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-137","SUBJID":"id-137","SITEID":"USA-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":3.40697,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-03 19:18:43","TRTEDTM":"2022-05-03 13:18:43","TRT01SDTM":"2019-05-03 19:18:43","TRT01EDTM":"2021-05-03 07:18:43","TRT02SDTM":"2021-05-03 07:18:43","TRT02EDTM":"2022-05-03 13:18:43","AP01SDTM":"2019-05-03 19:18:43","AP01EDTM":"2021-05-03 07:18:43","AP02SDTM":"2021-05-03 07:18:43","AP02EDTM":"2022-05-03 13:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-19","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2317,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.30455,"AVALU":"mg/L","BASE2":6.51252,"BASE":9.36761,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.79203,"PCHG2":27.51672,"CHG":-1.06307,"PCHG":-11.34832,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-20 19:18:43","ADY":140,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-137","SUBJID":"id-137","SITEID":"USA-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":3.40697,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-03 19:18:43","TRTEDTM":"2022-05-03 13:18:43","TRT01SDTM":"2019-05-03 19:18:43","TRT01EDTM":"2021-05-03 07:18:43","TRT02SDTM":"2021-05-03 07:18:43","TRT02EDTM":"2022-05-03 13:18:43","AP01SDTM":"2019-05-03 19:18:43","AP01EDTM":"2021-05-03 07:18:43","AP02SDTM":"2021-05-03 07:18:43","AP02EDTM":"2022-05-03 13:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-19","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6635,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.02661,"AVALU":"mg/L","BASE2":6.51252,"BASE":9.36761,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.51409,"PCHG2":23.24891,"CHG":-1.34101,"PCHG":-14.31537,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-01 19:18:43","ADY":395,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-137","SUBJID":"id-137","SITEID":"USA-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":3.40697,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-03 19:18:43","TRTEDTM":"2022-05-03 13:18:43","TRT01SDTM":"2019-05-03 19:18:43","TRT01EDTM":"2021-05-03 07:18:43","TRT02SDTM":"2021-05-03 07:18:43","TRT02EDTM":"2022-05-03 13:18:43","AP01SDTM":"2019-05-03 19:18:43","AP01EDTM":"2021-05-03 07:18:43","AP02SDTM":"2021-05-03 07:18:43","AP02EDTM":"2022-05-03 13:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-19","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3904,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.62666,"AVALU":"mg/L","BASE2":6.51252,"BASE":9.36761,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.11414,"PCHG2":32.46273,"CHG":-0.74096,"PCHG":-7.90977,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-18 19:18:43","ADY":777,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-137","SUBJID":"id-137","SITEID":"USA-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":3.40697,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-03 19:18:43","TRTEDTM":"2022-05-03 13:18:43","TRT01SDTM":"2019-05-03 19:18:43","TRT01EDTM":"2021-05-03 07:18:43","TRT02SDTM":"2021-05-03 07:18:43","TRT02EDTM":"2022-05-03 13:18:43","AP01SDTM":"2019-05-03 19:18:43","AP01EDTM":"2021-05-03 07:18:43","AP02SDTM":"2021-05-03 07:18:43","AP02EDTM":"2022-05-03 13:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-19","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3414,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.1471,"AVALU":"mg/L","BASE2":6.51252,"BASE":9.36761,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.63459,"PCHG2":71.1643,"CHG":1.77949,"PCHG":18.99618,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-03-01 19:18:43","ADY":1033,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-137","SUBJID":"id-137","SITEID":"USA-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":3.40697,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-03 19:18:43","TRTEDTM":"2022-05-03 13:18:43","TRT01SDTM":"2019-05-03 19:18:43","TRT01EDTM":"2021-05-03 07:18:43","TRT02SDTM":"2021-05-03 07:18:43","TRT02EDTM":"2022-05-03 13:18:43","AP01SDTM":"2019-05-03 19:18:43","AP01EDTM":"2021-05-03 07:18:43","AP02SDTM":"2021-05-03 07:18:43","AP02EDTM":"2022-05-03 13:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-19","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6446,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.89967,"AVALU":"mg/L","BASE2":6.51252,"BASE":9.36761,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.38715,"PCHG2":52.00992,"CHG":0.53206,"PCHG":5.67975,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-03 19:18:43","ADY":1035,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-137","SUBJID":"id-137","SITEID":"USA-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":3.40697,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-03 19:18:43","TRTEDTM":"2022-05-03 13:18:43","TRT01SDTM":"2019-05-03 19:18:43","TRT01EDTM":"2021-05-03 07:18:43","TRT02SDTM":"2021-05-03 07:18:43","TRT02EDTM":"2022-05-03 13:18:43","AP01SDTM":"2019-05-03 19:18:43","AP01EDTM":"2021-05-03 07:18:43","AP02SDTM":"2021-05-03 07:18:43","AP02EDTM":"2022-05-03 13:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-19","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4539,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94086,"AVALU":"g/L","BASE2":2.94086,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-06-03 19:18:43","ADY":31,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-137","SUBJID":"id-137","SITEID":"USA-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":3.40697,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-03 19:18:43","TRTEDTM":"2022-05-03 13:18:43","TRT01SDTM":"2019-05-03 19:18:43","TRT01EDTM":"2021-05-03 07:18:43","TRT02SDTM":"2021-05-03 07:18:43","TRT02EDTM":"2022-05-03 13:18:43","AP01SDTM":"2019-05-03 19:18:43","AP01EDTM":"2021-05-03 07:18:43","AP02SDTM":"2021-05-03 07:18:43","AP02EDTM":"2022-05-03 13:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-19","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4936,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96894,"AVALU":"g/L","BASE2":2.94086,"BASE":2.96894,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.02808,"PCHG2":0.95491,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-08-02 19:18:43","ADY":91,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-137","SUBJID":"id-137","SITEID":"USA-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":3.40697,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-03 19:18:43","TRTEDTM":"2022-05-03 13:18:43","TRT01SDTM":"2019-05-03 19:18:43","TRT01EDTM":"2021-05-03 07:18:43","TRT02SDTM":"2021-05-03 07:18:43","TRT02EDTM":"2022-05-03 13:18:43","AP01SDTM":"2019-05-03 19:18:43","AP01EDTM":"2021-05-03 07:18:43","AP02SDTM":"2021-05-03 07:18:43","AP02EDTM":"2022-05-03 13:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-19","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4980,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92231,"AVALU":"g/L","BASE2":2.94086,"BASE":2.96894,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01855,"PCHG2":-0.63067,"CHG":-0.04663,"PCHG":-1.57058,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-20 19:18:43","ADY":140,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-137","SUBJID":"id-137","SITEID":"USA-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":3.40697,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-03 19:18:43","TRTEDTM":"2022-05-03 13:18:43","TRT01SDTM":"2019-05-03 19:18:43","TRT01EDTM":"2021-05-03 07:18:43","TRT02SDTM":"2021-05-03 07:18:43","TRT02EDTM":"2022-05-03 13:18:43","AP01SDTM":"2019-05-03 19:18:43","AP01EDTM":"2021-05-03 07:18:43","AP02SDTM":"2021-05-03 07:18:43","AP02EDTM":"2022-05-03 13:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-19","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7099,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92008,"AVALU":"g/L","BASE2":2.94086,"BASE":2.96894,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02078,"PCHG2":-0.70652,"CHG":-0.04886,"PCHG":-1.64571,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-01 19:18:43","ADY":395,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-137","SUBJID":"id-137","SITEID":"USA-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":3.40697,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-03 19:18:43","TRTEDTM":"2022-05-03 13:18:43","TRT01SDTM":"2019-05-03 19:18:43","TRT01EDTM":"2021-05-03 07:18:43","TRT02SDTM":"2021-05-03 07:18:43","TRT02EDTM":"2022-05-03 13:18:43","AP01SDTM":"2019-05-03 19:18:43","AP01EDTM":"2021-05-03 07:18:43","AP02SDTM":"2021-05-03 07:18:43","AP02EDTM":"2022-05-03 13:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-19","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5948,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.71967,"AVALU":"g/L","BASE2":2.94086,"BASE":2.96894,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.22119,"PCHG2":-7.52127,"CHG":-0.24927,"PCHG":-8.396,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-18 19:18:43","ADY":777,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-137","SUBJID":"id-137","SITEID":"USA-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":3.40697,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-03 19:18:43","TRTEDTM":"2022-05-03 13:18:43","TRT01SDTM":"2019-05-03 19:18:43","TRT01EDTM":"2021-05-03 07:18:43","TRT02SDTM":"2021-05-03 07:18:43","TRT02EDTM":"2022-05-03 13:18:43","AP01SDTM":"2019-05-03 19:18:43","AP01EDTM":"2021-05-03 07:18:43","AP02SDTM":"2021-05-03 07:18:43","AP02EDTM":"2022-05-03 13:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-19","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5354,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86579,"AVALU":"g/L","BASE2":2.94086,"BASE":2.96894,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07507,"PCHG2":-2.55258,"CHG":-0.10315,"PCHG":-3.47431,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-01 19:18:43","ADY":1033,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-137","SUBJID":"id-137","SITEID":"USA-1","AGE":29,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":3.40697,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-01","TRTSDTM":"2019-05-03 19:18:43","TRTEDTM":"2022-05-03 13:18:43","TRT01SDTM":"2019-05-03 19:18:43","TRT01EDTM":"2021-05-03 07:18:43","TRT02SDTM":"2021-05-03 07:18:43","TRT02EDTM":"2022-05-03 13:18:43","AP01SDTM":"2019-05-03 19:18:43","AP01EDTM":"2021-05-03 07:18:43","AP02SDTM":"2021-05-03 07:18:43","AP02EDTM":"2022-05-03 13:18:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-03","EOSDY":1096,"LSTALVDT":"2022-05-19","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":517,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.09418,"AVALU":"g/L","BASE2":2.94086,"BASE":2.96894,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.15332,"PCHG2":5.21357,"CHG":0.12524,"PCHG":4.21838,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-03-03 19:18:43","ADY":1035,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-138","SUBJID":"id-138","SITEID":"USA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.96586,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-15 03:09:56","TRTEDTM":"2023-08-15 21:09:56","TRT01SDTM":"2020-08-15 03:09:56","TRT01EDTM":"2022-08-15 15:09:56","TRT02SDTM":"2022-08-15 15:09:56","TRT02EDTM":"2023-08-15 21:09:56","AP01SDTM":"2020-08-15 03:09:56","AP01EDTM":"2022-08-15 15:09:56","AP02SDTM":"2022-08-15 15:09:56","AP02EDTM":"2023-08-15 21:09:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-15","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5885,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.55137,"AVALU":"U/L","BASE2":27.55137,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-26 03:09:56","ADY":376,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-138","SUBJID":"id-138","SITEID":"USA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.96586,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-15 03:09:56","TRTEDTM":"2023-08-15 21:09:56","TRT01SDTM":"2020-08-15 03:09:56","TRT01EDTM":"2022-08-15 15:09:56","TRT02SDTM":"2022-08-15 15:09:56","TRT02EDTM":"2023-08-15 21:09:56","AP01SDTM":"2020-08-15 03:09:56","AP01EDTM":"2022-08-15 15:09:56","AP02SDTM":"2022-08-15 15:09:56","AP02EDTM":"2023-08-15 21:09:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-15","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3409,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.52358,"AVALU":"U/L","BASE2":27.55137,"BASE":34.52358,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":6.97221,"PCHG2":25.30623,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-15 03:09:56","ADY":457,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-138","SUBJID":"id-138","SITEID":"USA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.96586,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-15 03:09:56","TRTEDTM":"2023-08-15 21:09:56","TRT01SDTM":"2020-08-15 03:09:56","TRT01EDTM":"2022-08-15 15:09:56","TRT02SDTM":"2022-08-15 15:09:56","TRT02EDTM":"2023-08-15 21:09:56","AP01SDTM":"2020-08-15 03:09:56","AP01EDTM":"2022-08-15 15:09:56","AP02SDTM":"2022-08-15 15:09:56","AP02EDTM":"2023-08-15 21:09:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-15","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4675,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.09796,"AVALU":"U/L","BASE2":27.55137,"BASE":34.52358,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.4534,"PCHG2":-5.27525,"CHG":-8.42561,"PCHG":-24.40539,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-21 03:09:56","ADY":583,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-138","SUBJID":"id-138","SITEID":"USA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.96586,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-15 03:09:56","TRTEDTM":"2023-08-15 21:09:56","TRT01SDTM":"2020-08-15 03:09:56","TRT01EDTM":"2022-08-15 15:09:56","TRT02SDTM":"2022-08-15 15:09:56","TRT02EDTM":"2023-08-15 21:09:56","AP01SDTM":"2020-08-15 03:09:56","AP01EDTM":"2022-08-15 15:09:56","AP02SDTM":"2022-08-15 15:09:56","AP02EDTM":"2023-08-15 21:09:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-15","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4481,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.6342,"AVALU":"U/L","BASE2":27.55137,"BASE":34.52358,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.91717,"PCHG2":-25.10645,"CHG":-13.88938,"PCHG":-40.23158,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-05 03:09:56","ADY":628,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-138","SUBJID":"id-138","SITEID":"USA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.96586,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-15 03:09:56","TRTEDTM":"2023-08-15 21:09:56","TRT01SDTM":"2020-08-15 03:09:56","TRT01EDTM":"2022-08-15 15:09:56","TRT02SDTM":"2022-08-15 15:09:56","TRT02EDTM":"2023-08-15 21:09:56","AP01SDTM":"2020-08-15 03:09:56","AP01EDTM":"2022-08-15 15:09:56","AP02SDTM":"2022-08-15 15:09:56","AP02EDTM":"2023-08-15 21:09:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-15","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4049,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.11462,"AVALU":"U/L","BASE2":27.55137,"BASE":34.52358,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.43675,"PCHG2":-34.25146,"CHG":-16.40896,"PCHG":-47.52971,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-26 03:09:56","ADY":680,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-138","SUBJID":"id-138","SITEID":"USA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.96586,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-15 03:09:56","TRTEDTM":"2023-08-15 21:09:56","TRT01SDTM":"2020-08-15 03:09:56","TRT01EDTM":"2022-08-15 15:09:56","TRT02SDTM":"2022-08-15 15:09:56","TRT02EDTM":"2023-08-15 21:09:56","AP01SDTM":"2020-08-15 03:09:56","AP01EDTM":"2022-08-15 15:09:56","AP02SDTM":"2022-08-15 15:09:56","AP02EDTM":"2023-08-15 21:09:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-15","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5050,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.72007,"AVALU":"U/L","BASE2":27.55137,"BASE":34.52358,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-26.8313,"PCHG2":-97.38644,"CHG":-33.80351,"PCHG":-97.91426,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-10-08 03:09:56","ADY":784,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-138","SUBJID":"id-138","SITEID":"USA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.96586,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-15 03:09:56","TRTEDTM":"2023-08-15 21:09:56","TRT01SDTM":"2020-08-15 03:09:56","TRT01EDTM":"2022-08-15 15:09:56","TRT02SDTM":"2022-08-15 15:09:56","TRT02EDTM":"2023-08-15 21:09:56","AP01SDTM":"2020-08-15 03:09:56","AP01EDTM":"2022-08-15 15:09:56","AP02SDTM":"2022-08-15 15:09:56","AP02EDTM":"2023-08-15 21:09:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-15","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6300,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.7813,"AVALU":"U/L","BASE2":27.55137,"BASE":34.52358,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.77007,"PCHG2":-20.94295,"CHG":-12.74228,"PCHG":-36.90892,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-27 03:09:56","ADY":926,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-138","SUBJID":"id-138","SITEID":"USA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.96586,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-15 03:09:56","TRTEDTM":"2023-08-15 21:09:56","TRT01SDTM":"2020-08-15 03:09:56","TRT01EDTM":"2022-08-15 15:09:56","TRT02SDTM":"2022-08-15 15:09:56","TRT02EDTM":"2023-08-15 21:09:56","AP01SDTM":"2020-08-15 03:09:56","AP01EDTM":"2022-08-15 15:09:56","AP02SDTM":"2022-08-15 15:09:56","AP02EDTM":"2023-08-15 21:09:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-15","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":331,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.60124,"AVALU":"mg/L","BASE2":8.60124,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-08-26 03:09:56","ADY":376,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-138","SUBJID":"id-138","SITEID":"USA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.96586,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-15 03:09:56","TRTEDTM":"2023-08-15 21:09:56","TRT01SDTM":"2020-08-15 03:09:56","TRT01EDTM":"2022-08-15 15:09:56","TRT02SDTM":"2022-08-15 15:09:56","TRT02EDTM":"2023-08-15 21:09:56","AP01SDTM":"2020-08-15 03:09:56","AP01EDTM":"2022-08-15 15:09:56","AP02SDTM":"2022-08-15 15:09:56","AP02EDTM":"2023-08-15 21:09:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-15","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4069,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.12129,"AVALU":"mg/L","BASE2":8.60124,"BASE":10.12129,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.52004,"PCHG2":17.67237,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2021-11-15 03:09:56","ADY":457,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-138","SUBJID":"id-138","SITEID":"USA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.96586,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-15 03:09:56","TRTEDTM":"2023-08-15 21:09:56","TRT01SDTM":"2020-08-15 03:09:56","TRT01EDTM":"2022-08-15 15:09:56","TRT02SDTM":"2022-08-15 15:09:56","TRT02EDTM":"2023-08-15 21:09:56","AP01SDTM":"2020-08-15 03:09:56","AP01EDTM":"2022-08-15 15:09:56","AP02SDTM":"2022-08-15 15:09:56","AP02EDTM":"2023-08-15 21:09:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-15","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7774,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.3311,"AVALU":"mg/L","BASE2":8.60124,"BASE":10.12129,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.72985,"PCHG2":8.48545,"CHG":-0.79019,"PCHG":-7.8072,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-03-21 03:09:56","ADY":583,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-138","SUBJID":"id-138","SITEID":"USA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.96586,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-15 03:09:56","TRTEDTM":"2023-08-15 21:09:56","TRT01SDTM":"2020-08-15 03:09:56","TRT01EDTM":"2022-08-15 15:09:56","TRT02SDTM":"2022-08-15 15:09:56","TRT02EDTM":"2023-08-15 21:09:56","AP01SDTM":"2020-08-15 03:09:56","AP01EDTM":"2022-08-15 15:09:56","AP02SDTM":"2022-08-15 15:09:56","AP02EDTM":"2023-08-15 21:09:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-15","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3142,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.19058,"AVALU":"mg/L","BASE2":8.60124,"BASE":10.12129,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.58934,"PCHG2":6.85182,"CHG":-0.9307,"PCHG":-9.19549,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-05-05 03:09:56","ADY":628,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-138","SUBJID":"id-138","SITEID":"USA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.96586,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-15 03:09:56","TRTEDTM":"2023-08-15 21:09:56","TRT01SDTM":"2020-08-15 03:09:56","TRT01EDTM":"2022-08-15 15:09:56","TRT02SDTM":"2022-08-15 15:09:56","TRT02EDTM":"2023-08-15 21:09:56","AP01SDTM":"2020-08-15 03:09:56","AP01EDTM":"2022-08-15 15:09:56","AP02SDTM":"2022-08-15 15:09:56","AP02EDTM":"2023-08-15 21:09:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-15","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1146,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.50459,"AVALU":"mg/L","BASE2":8.60124,"BASE":10.12129,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.90335,"PCHG2":10.5025,"CHG":-0.6167,"PCHG":-6.09307,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-06-26 03:09:56","ADY":680,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-138","SUBJID":"id-138","SITEID":"USA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.96586,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-15 03:09:56","TRTEDTM":"2023-08-15 21:09:56","TRT01SDTM":"2020-08-15 03:09:56","TRT01EDTM":"2022-08-15 15:09:56","TRT02SDTM":"2022-08-15 15:09:56","TRT02EDTM":"2023-08-15 21:09:56","AP01SDTM":"2020-08-15 03:09:56","AP01EDTM":"2022-08-15 15:09:56","AP02SDTM":"2022-08-15 15:09:56","AP02EDTM":"2023-08-15 21:09:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-15","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1960,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.24599,"AVALU":"mg/L","BASE2":8.60124,"BASE":10.12129,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.64475,"PCHG2":7.49596,"CHG":-0.8753,"PCHG":-8.64809,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-10-08 03:09:56","ADY":784,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-138","SUBJID":"id-138","SITEID":"USA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.96586,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-15 03:09:56","TRTEDTM":"2023-08-15 21:09:56","TRT01SDTM":"2020-08-15 03:09:56","TRT01EDTM":"2022-08-15 15:09:56","TRT02SDTM":"2022-08-15 15:09:56","TRT02EDTM":"2023-08-15 21:09:56","AP01SDTM":"2020-08-15 03:09:56","AP01EDTM":"2022-08-15 15:09:56","AP02SDTM":"2022-08-15 15:09:56","AP02EDTM":"2023-08-15 21:09:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-15","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":92,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.84099,"AVALU":"mg/L","BASE2":8.60124,"BASE":10.12129,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.23974,"PCHG2":14.41354,"CHG":-0.2803,"PCHG":-2.76941,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2023-02-27 03:09:56","ADY":926,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-138","SUBJID":"id-138","SITEID":"USA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.96586,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-15 03:09:56","TRTEDTM":"2023-08-15 21:09:56","TRT01SDTM":"2020-08-15 03:09:56","TRT01EDTM":"2022-08-15 15:09:56","TRT02SDTM":"2022-08-15 15:09:56","TRT02EDTM":"2023-08-15 21:09:56","AP01SDTM":"2020-08-15 03:09:56","AP01EDTM":"2022-08-15 15:09:56","AP02SDTM":"2022-08-15 15:09:56","AP02EDTM":"2023-08-15 21:09:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-15","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6485,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93906,"AVALU":"g/L","BASE2":2.93906,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-08-26 03:09:56","ADY":376,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-138","SUBJID":"id-138","SITEID":"USA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.96586,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-15 03:09:56","TRTEDTM":"2023-08-15 21:09:56","TRT01SDTM":"2020-08-15 03:09:56","TRT01EDTM":"2022-08-15 15:09:56","TRT02SDTM":"2022-08-15 15:09:56","TRT02EDTM":"2023-08-15 21:09:56","AP01SDTM":"2020-08-15 03:09:56","AP01EDTM":"2022-08-15 15:09:56","AP02SDTM":"2022-08-15 15:09:56","AP02EDTM":"2023-08-15 21:09:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-15","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6176,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00593,"AVALU":"g/L","BASE2":2.93906,"BASE":3.00593,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.06687,"PCHG2":2.27534,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2021-11-15 03:09:56","ADY":457,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-138","SUBJID":"id-138","SITEID":"USA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.96586,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-15 03:09:56","TRTEDTM":"2023-08-15 21:09:56","TRT01SDTM":"2020-08-15 03:09:56","TRT01EDTM":"2022-08-15 15:09:56","TRT02SDTM":"2022-08-15 15:09:56","TRT02EDTM":"2023-08-15 21:09:56","AP01SDTM":"2020-08-15 03:09:56","AP01EDTM":"2022-08-15 15:09:56","AP02SDTM":"2022-08-15 15:09:56","AP02EDTM":"2023-08-15 21:09:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-15","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6562,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02402,"AVALU":"g/L","BASE2":2.93906,"BASE":3.00593,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08496,"PCHG2":2.89089,"CHG":0.01809,"PCHG":0.60186,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"1","BTOXGR":"3","ADTM":"2022-03-21 03:09:56","ADY":583,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-138","SUBJID":"id-138","SITEID":"USA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.96586,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-15 03:09:56","TRTEDTM":"2023-08-15 21:09:56","TRT01SDTM":"2020-08-15 03:09:56","TRT01EDTM":"2022-08-15 15:09:56","TRT02SDTM":"2022-08-15 15:09:56","TRT02EDTM":"2023-08-15 21:09:56","AP01SDTM":"2020-08-15 03:09:56","AP01EDTM":"2022-08-15 15:09:56","AP02SDTM":"2022-08-15 15:09:56","AP02EDTM":"2023-08-15 21:09:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-15","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1070,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89921,"AVALU":"g/L","BASE2":2.93906,"BASE":3.00593,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03985,"PCHG2":-1.35587,"CHG":-0.10672,"PCHG":-3.55043,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-05-05 03:09:56","ADY":628,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-138","SUBJID":"id-138","SITEID":"USA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.96586,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-15 03:09:56","TRTEDTM":"2023-08-15 21:09:56","TRT01SDTM":"2020-08-15 03:09:56","TRT01EDTM":"2022-08-15 15:09:56","TRT02SDTM":"2022-08-15 15:09:56","TRT02EDTM":"2023-08-15 21:09:56","AP01SDTM":"2020-08-15 03:09:56","AP01EDTM":"2022-08-15 15:09:56","AP02SDTM":"2022-08-15 15:09:56","AP02EDTM":"2023-08-15 21:09:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-15","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2968,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86968,"AVALU":"g/L","BASE2":2.93906,"BASE":3.00593,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06938,"PCHG2":-2.36051,"CHG":-0.13625,"PCHG":-4.53271,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-06-26 03:09:56","ADY":680,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-138","SUBJID":"id-138","SITEID":"USA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.96586,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-15 03:09:56","TRTEDTM":"2023-08-15 21:09:56","TRT01SDTM":"2020-08-15 03:09:56","TRT01EDTM":"2022-08-15 15:09:56","TRT02SDTM":"2022-08-15 15:09:56","TRT02EDTM":"2023-08-15 21:09:56","AP01SDTM":"2020-08-15 03:09:56","AP01EDTM":"2022-08-15 15:09:56","AP02SDTM":"2022-08-15 15:09:56","AP02EDTM":"2023-08-15 21:09:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-15","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1738,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.06179,"AVALU":"g/L","BASE2":2.93906,"BASE":3.00593,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12274,"PCHG2":4.17614,"CHG":0.05587,"PCHG":1.85851,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"3","BTOXGR":"3","ADTM":"2022-10-08 03:09:56","ADY":784,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-138","SUBJID":"id-138","SITEID":"USA-1","AGE":36,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.96586,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-15 03:09:56","TRTEDTM":"2023-08-15 21:09:56","TRT01SDTM":"2020-08-15 03:09:56","TRT01EDTM":"2022-08-15 15:09:56","TRT02SDTM":"2022-08-15 15:09:56","TRT02EDTM":"2023-08-15 21:09:56","AP01SDTM":"2020-08-15 03:09:56","AP01EDTM":"2022-08-15 15:09:56","AP02SDTM":"2022-08-15 15:09:56","AP02EDTM":"2023-08-15 21:09:56","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-15","EOSDY":1096,"LSTALVDT":"2023-09-04","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7765,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01072,"AVALU":"g/L","BASE2":2.93906,"BASE":3.00593,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07166,"PCHG2":2.43828,"CHG":0.00479,"PCHG":0.15932,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"3","BTOXGR":"3","ADTM":"2023-02-27 03:09:56","ADY":926,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-207","SUBJID":"id-207","SITEID":"USA-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":5.30656,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 21:27:58","TRTEDTM":"2022-02-17 23:02:32","TRT01SDTM":"2021-01-14 21:27:58","TRT01EDTM":"2021-02-17 17:02:32","TRT02SDTM":"2021-02-17 17:02:32","TRT02EDTM":"2022-02-17 23:02:32","AP01SDTM":"2021-01-14 21:27:58","AP01EDTM":"2021-02-17 17:02:32","AP02SDTM":"2021-02-17 17:02:32","AP02EDTM":"2022-02-17 23:02:32","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":400,"DCSREAS":"DEATH","DTHDT":"2022-03-04","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-04","DTHADY":413,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6687,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.64342,"AVALU":"U/L","BASE2":19.64342,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-15 21:27:58","ADY":1,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-207","SUBJID":"id-207","SITEID":"USA-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":5.30656,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 21:27:58","TRTEDTM":"2022-02-17 23:02:32","TRT01SDTM":"2021-01-14 21:27:58","TRT01EDTM":"2021-02-17 17:02:32","TRT02SDTM":"2021-02-17 17:02:32","TRT02EDTM":"2022-02-17 23:02:32","AP01SDTM":"2021-01-14 21:27:58","AP01EDTM":"2021-02-17 17:02:32","AP02SDTM":"2021-02-17 17:02:32","AP02EDTM":"2022-02-17 23:02:32","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":400,"DCSREAS":"DEATH","DTHDT":"2022-03-04","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-04","DTHADY":413,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4474,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.95609,"AVALU":"U/L","BASE2":19.64342,"BASE":7.95609,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-11.68733,"PCHG2":-59.49742,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-28 21:27:58","ADY":14,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-207","SUBJID":"id-207","SITEID":"USA-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":5.30656,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 21:27:58","TRTEDTM":"2022-02-17 23:02:32","TRT01SDTM":"2021-01-14 21:27:58","TRT01EDTM":"2021-02-17 17:02:32","TRT02SDTM":"2021-02-17 17:02:32","TRT02EDTM":"2022-02-17 23:02:32","AP01SDTM":"2021-01-14 21:27:58","AP01EDTM":"2021-02-17 17:02:32","AP02SDTM":"2021-02-17 17:02:32","AP02EDTM":"2022-02-17 23:02:32","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":400,"DCSREAS":"DEATH","DTHDT":"2022-03-04","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-04","DTHADY":413,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6044,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":40.23044,"AVALU":"U/L","BASE2":19.64342,"BASE":7.95609,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":20.58703,"PCHG2":104.80368,"CHG":32.27435,"PCHG":405.65586,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-30 21:27:58","ADY":75,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-207","SUBJID":"id-207","SITEID":"USA-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":5.30656,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 21:27:58","TRTEDTM":"2022-02-17 23:02:32","TRT01SDTM":"2021-01-14 21:27:58","TRT01EDTM":"2021-02-17 17:02:32","TRT02SDTM":"2021-02-17 17:02:32","TRT02EDTM":"2022-02-17 23:02:32","AP01SDTM":"2021-01-14 21:27:58","AP01EDTM":"2021-02-17 17:02:32","AP02SDTM":"2021-02-17 17:02:32","AP02EDTM":"2022-02-17 23:02:32","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":400,"DCSREAS":"DEATH","DTHDT":"2022-03-04","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-04","DTHADY":413,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":646,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.41317,"AVALU":"U/L","BASE2":19.64342,"BASE":7.95609,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.23025,"PCHG2":-6.26292,"CHG":10.45707,"PCHG":131.43481,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-28 21:27:58","ADY":165,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-207","SUBJID":"id-207","SITEID":"USA-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":5.30656,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 21:27:58","TRTEDTM":"2022-02-17 23:02:32","TRT01SDTM":"2021-01-14 21:27:58","TRT01EDTM":"2021-02-17 17:02:32","TRT02SDTM":"2021-02-17 17:02:32","TRT02EDTM":"2022-02-17 23:02:32","AP01SDTM":"2021-01-14 21:27:58","AP01EDTM":"2021-02-17 17:02:32","AP02SDTM":"2021-02-17 17:02:32","AP02EDTM":"2022-02-17 23:02:32","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":400,"DCSREAS":"DEATH","DTHDT":"2022-03-04","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-04","DTHADY":413,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2286,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.65823,"AVALU":"U/L","BASE2":19.64342,"BASE":7.95609,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.98519,"PCHG2":-35.55996,"CHG":4.70213,"PCHG":59.10106,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-18 21:27:58","ADY":216,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-207","SUBJID":"id-207","SITEID":"USA-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":5.30656,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 21:27:58","TRTEDTM":"2022-02-17 23:02:32","TRT01SDTM":"2021-01-14 21:27:58","TRT01EDTM":"2021-02-17 17:02:32","TRT02SDTM":"2021-02-17 17:02:32","TRT02EDTM":"2022-02-17 23:02:32","AP01SDTM":"2021-01-14 21:27:58","AP01EDTM":"2021-02-17 17:02:32","AP02SDTM":"2021-02-17 17:02:32","AP02EDTM":"2022-02-17 23:02:32","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":400,"DCSREAS":"DEATH","DTHDT":"2022-03-04","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-04","DTHADY":413,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2190,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.75276,"AVALU":"U/L","BASE2":19.64342,"BASE":7.95609,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.89065,"PCHG2":-9.62488,"CHG":9.79667,"PCHG":123.13422,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-31 21:27:58","ADY":290,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-207","SUBJID":"id-207","SITEID":"USA-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":5.30656,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 21:27:58","TRTEDTM":"2022-02-17 23:02:32","TRT01SDTM":"2021-01-14 21:27:58","TRT01EDTM":"2021-02-17 17:02:32","TRT02SDTM":"2021-02-17 17:02:32","TRT02EDTM":"2022-02-17 23:02:32","AP01SDTM":"2021-01-14 21:27:58","AP01EDTM":"2021-02-17 17:02:32","AP02SDTM":"2021-02-17 17:02:32","AP02EDTM":"2022-02-17 23:02:32","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":400,"DCSREAS":"DEATH","DTHDT":"2022-03-04","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-04","DTHADY":413,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4352,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.79365,"AVALU":"U/L","BASE2":19.64342,"BASE":7.95609,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.15023,"PCHG2":16.03708,"CHG":14.83756,"PCHG":186.49305,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-10 21:27:58","ADY":330,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-207","SUBJID":"id-207","SITEID":"USA-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":5.30656,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 21:27:58","TRTEDTM":"2022-02-17 23:02:32","TRT01SDTM":"2021-01-14 21:27:58","TRT01EDTM":"2021-02-17 17:02:32","TRT02SDTM":"2021-02-17 17:02:32","TRT02EDTM":"2022-02-17 23:02:32","AP01SDTM":"2021-01-14 21:27:58","AP01EDTM":"2021-02-17 17:02:32","AP02SDTM":"2021-02-17 17:02:32","AP02EDTM":"2022-02-17 23:02:32","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":400,"DCSREAS":"DEATH","DTHDT":"2022-03-04","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-04","DTHADY":413,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":952,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.3953,"AVALU":"mg/L","BASE2":8.3953,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-15 21:27:58","ADY":1,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-207","SUBJID":"id-207","SITEID":"USA-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":5.30656,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 21:27:58","TRTEDTM":"2022-02-17 23:02:32","TRT01SDTM":"2021-01-14 21:27:58","TRT01EDTM":"2021-02-17 17:02:32","TRT02SDTM":"2021-02-17 17:02:32","TRT02EDTM":"2022-02-17 23:02:32","AP01SDTM":"2021-01-14 21:27:58","AP01EDTM":"2021-02-17 17:02:32","AP02SDTM":"2021-02-17 17:02:32","AP02EDTM":"2022-02-17 23:02:32","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":400,"DCSREAS":"DEATH","DTHDT":"2022-03-04","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-04","DTHADY":413,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1131,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.25601,"AVALU":"mg/L","BASE2":8.3953,"BASE":8.25601,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.13929,"PCHG2":-1.65911,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-28 21:27:58","ADY":14,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-207","SUBJID":"id-207","SITEID":"USA-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":5.30656,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 21:27:58","TRTEDTM":"2022-02-17 23:02:32","TRT01SDTM":"2021-01-14 21:27:58","TRT01EDTM":"2021-02-17 17:02:32","TRT02SDTM":"2021-02-17 17:02:32","TRT02EDTM":"2022-02-17 23:02:32","AP01SDTM":"2021-01-14 21:27:58","AP01EDTM":"2021-02-17 17:02:32","AP02SDTM":"2021-02-17 17:02:32","AP02EDTM":"2022-02-17 23:02:32","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":400,"DCSREAS":"DEATH","DTHDT":"2022-03-04","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-04","DTHADY":413,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2391,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.81538,"AVALU":"mg/L","BASE2":8.3953,"BASE":8.25601,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.42008,"PCHG2":5.00375,"CHG":0.55937,"PCHG":6.77527,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-30 21:27:58","ADY":75,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-207","SUBJID":"id-207","SITEID":"USA-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":5.30656,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 21:27:58","TRTEDTM":"2022-02-17 23:02:32","TRT01SDTM":"2021-01-14 21:27:58","TRT01EDTM":"2021-02-17 17:02:32","TRT02SDTM":"2021-02-17 17:02:32","TRT02EDTM":"2022-02-17 23:02:32","AP01SDTM":"2021-01-14 21:27:58","AP01EDTM":"2021-02-17 17:02:32","AP02SDTM":"2021-02-17 17:02:32","AP02EDTM":"2022-02-17 23:02:32","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":400,"DCSREAS":"DEATH","DTHDT":"2022-03-04","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-04","DTHADY":413,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7803,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.63377,"AVALU":"mg/L","BASE2":8.3953,"BASE":8.25601,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.23848,"PCHG2":2.84059,"CHG":0.37776,"PCHG":4.57561,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-28 21:27:58","ADY":165,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-207","SUBJID":"id-207","SITEID":"USA-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":5.30656,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 21:27:58","TRTEDTM":"2022-02-17 23:02:32","TRT01SDTM":"2021-01-14 21:27:58","TRT01EDTM":"2021-02-17 17:02:32","TRT02SDTM":"2021-02-17 17:02:32","TRT02EDTM":"2022-02-17 23:02:32","AP01SDTM":"2021-01-14 21:27:58","AP01EDTM":"2021-02-17 17:02:32","AP02SDTM":"2021-02-17 17:02:32","AP02EDTM":"2022-02-17 23:02:32","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":400,"DCSREAS":"DEATH","DTHDT":"2022-03-04","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-04","DTHADY":413,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":495,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.32996,"AVALU":"mg/L","BASE2":8.3953,"BASE":8.25601,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.93467,"PCHG2":34.95608,"CHG":3.07395,"PCHG":37.23293,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-08-18 21:27:58","ADY":216,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-207","SUBJID":"id-207","SITEID":"USA-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":5.30656,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 21:27:58","TRTEDTM":"2022-02-17 23:02:32","TRT01SDTM":"2021-01-14 21:27:58","TRT01EDTM":"2021-02-17 17:02:32","TRT02SDTM":"2021-02-17 17:02:32","TRT02EDTM":"2022-02-17 23:02:32","AP01SDTM":"2021-01-14 21:27:58","AP01EDTM":"2021-02-17 17:02:32","AP02SDTM":"2021-02-17 17:02:32","AP02EDTM":"2022-02-17 23:02:32","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":400,"DCSREAS":"DEATH","DTHDT":"2022-03-04","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-04","DTHADY":413,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3147,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.39735,"AVALU":"mg/L","BASE2":8.3953,"BASE":8.25601,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.00205,"PCHG2":11.93587,"CHG":1.14134,"PCHG":13.82434,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-31 21:27:58","ADY":290,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-207","SUBJID":"id-207","SITEID":"USA-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":5.30656,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 21:27:58","TRTEDTM":"2022-02-17 23:02:32","TRT01SDTM":"2021-01-14 21:27:58","TRT01EDTM":"2021-02-17 17:02:32","TRT02SDTM":"2021-02-17 17:02:32","TRT02EDTM":"2022-02-17 23:02:32","AP01SDTM":"2021-01-14 21:27:58","AP01EDTM":"2021-02-17 17:02:32","AP02SDTM":"2021-02-17 17:02:32","AP02EDTM":"2022-02-17 23:02:32","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":400,"DCSREAS":"DEATH","DTHDT":"2022-03-04","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-04","DTHADY":413,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2795,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.38631,"AVALU":"mg/L","BASE2":8.3953,"BASE":8.25601,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00899,"PCHG2":-0.10703,"CHG":0.1303,"PCHG":1.57827,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-10 21:27:58","ADY":330,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-207","SUBJID":"id-207","SITEID":"USA-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":5.30656,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 21:27:58","TRTEDTM":"2022-02-17 23:02:32","TRT01SDTM":"2021-01-14 21:27:58","TRT01EDTM":"2021-02-17 17:02:32","TRT02SDTM":"2021-02-17 17:02:32","TRT02EDTM":"2022-02-17 23:02:32","AP01SDTM":"2021-01-14 21:27:58","AP01EDTM":"2021-02-17 17:02:32","AP02SDTM":"2021-02-17 17:02:32","AP02EDTM":"2022-02-17 23:02:32","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":400,"DCSREAS":"DEATH","DTHDT":"2022-03-04","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-04","DTHADY":413,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4703,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82552,"AVALU":"g/L","BASE2":2.82552,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-15 21:27:58","ADY":1,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-207","SUBJID":"id-207","SITEID":"USA-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":5.30656,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 21:27:58","TRTEDTM":"2022-02-17 23:02:32","TRT01SDTM":"2021-01-14 21:27:58","TRT01EDTM":"2021-02-17 17:02:32","TRT02SDTM":"2021-02-17 17:02:32","TRT02EDTM":"2022-02-17 23:02:32","AP01SDTM":"2021-01-14 21:27:58","AP01EDTM":"2021-02-17 17:02:32","AP02SDTM":"2021-02-17 17:02:32","AP02EDTM":"2022-02-17 23:02:32","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":400,"DCSREAS":"DEATH","DTHDT":"2022-03-04","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-04","DTHADY":413,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3015,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94611,"AVALU":"g/L","BASE2":2.82552,"BASE":2.94611,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.12059,"PCHG2":4.26801,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-28 21:27:58","ADY":14,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-207","SUBJID":"id-207","SITEID":"USA-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":5.30656,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 21:27:58","TRTEDTM":"2022-02-17 23:02:32","TRT01SDTM":"2021-01-14 21:27:58","TRT01EDTM":"2021-02-17 17:02:32","TRT02SDTM":"2021-02-17 17:02:32","TRT02EDTM":"2022-02-17 23:02:32","AP01SDTM":"2021-01-14 21:27:58","AP01EDTM":"2021-02-17 17:02:32","AP02SDTM":"2021-02-17 17:02:32","AP02EDTM":"2022-02-17 23:02:32","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":400,"DCSREAS":"DEATH","DTHDT":"2022-03-04","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-04","DTHADY":413,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3247,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94511,"AVALU":"g/L","BASE2":2.82552,"BASE":2.94611,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11959,"PCHG2":4.23245,"CHG":-0.001,"PCHG":-0.0341,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-30 21:27:58","ADY":75,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-207","SUBJID":"id-207","SITEID":"USA-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":5.30656,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 21:27:58","TRTEDTM":"2022-02-17 23:02:32","TRT01SDTM":"2021-01-14 21:27:58","TRT01EDTM":"2021-02-17 17:02:32","TRT02SDTM":"2021-02-17 17:02:32","TRT02EDTM":"2022-02-17 23:02:32","AP01SDTM":"2021-01-14 21:27:58","AP01EDTM":"2021-02-17 17:02:32","AP02SDTM":"2021-02-17 17:02:32","AP02EDTM":"2022-02-17 23:02:32","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":400,"DCSREAS":"DEATH","DTHDT":"2022-03-04","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-04","DTHADY":413,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1276,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97662,"AVALU":"g/L","BASE2":2.82552,"BASE":2.94611,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1511,"PCHG2":5.34767,"CHG":0.03051,"PCHG":1.03547,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-28 21:27:58","ADY":165,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-207","SUBJID":"id-207","SITEID":"USA-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":5.30656,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 21:27:58","TRTEDTM":"2022-02-17 23:02:32","TRT01SDTM":"2021-01-14 21:27:58","TRT01EDTM":"2021-02-17 17:02:32","TRT02SDTM":"2021-02-17 17:02:32","TRT02EDTM":"2022-02-17 23:02:32","AP01SDTM":"2021-01-14 21:27:58","AP01EDTM":"2021-02-17 17:02:32","AP02SDTM":"2021-02-17 17:02:32","AP02EDTM":"2022-02-17 23:02:32","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":400,"DCSREAS":"DEATH","DTHDT":"2022-03-04","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-04","DTHADY":413,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1054,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92876,"AVALU":"g/L","BASE2":2.82552,"BASE":2.94611,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10324,"PCHG2":3.65384,"CHG":-0.01735,"PCHG":-0.58903,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-18 21:27:58","ADY":216,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-207","SUBJID":"id-207","SITEID":"USA-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":5.30656,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 21:27:58","TRTEDTM":"2022-02-17 23:02:32","TRT01SDTM":"2021-01-14 21:27:58","TRT01EDTM":"2021-02-17 17:02:32","TRT02SDTM":"2021-02-17 17:02:32","TRT02EDTM":"2022-02-17 23:02:32","AP01SDTM":"2021-01-14 21:27:58","AP01EDTM":"2021-02-17 17:02:32","AP02SDTM":"2021-02-17 17:02:32","AP02EDTM":"2022-02-17 23:02:32","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":400,"DCSREAS":"DEATH","DTHDT":"2022-03-04","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-04","DTHADY":413,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2099,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81407,"AVALU":"g/L","BASE2":2.82552,"BASE":2.94611,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01145,"PCHG2":-0.40507,"CHG":-0.13204,"PCHG":-4.48179,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-31 21:27:58","ADY":290,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-207","SUBJID":"id-207","SITEID":"USA-1","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":5.30656,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-01-13","TRTSDTM":"2021-01-14 21:27:58","TRTEDTM":"2022-02-17 23:02:32","TRT01SDTM":"2021-01-14 21:27:58","TRT01EDTM":"2021-02-17 17:02:32","TRT02SDTM":"2021-02-17 17:02:32","TRT02EDTM":"2022-02-17 23:02:32","AP01SDTM":"2021-01-14 21:27:58","AP01EDTM":"2021-02-17 17:02:32","AP02SDTM":"2021-02-17 17:02:32","AP02EDTM":"2022-02-17 23:02:32","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":400,"DCSREAS":"DEATH","DTHDT":"2022-03-04","DTHCAUS":"DISEASE PROGRESSION","DTHCAT":"PROGRESSIVE DISEASE","LDDTHELD":15,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-04","DTHADY":413,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4511,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95096,"AVALU":"g/L","BASE2":2.82552,"BASE":2.94611,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12544,"PCHG2":4.43969,"CHG":0.00485,"PCHG":0.16465,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-10 21:27:58","ADY":330,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-242","SUBJID":"id-242","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":13.87859,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 19:55:31","TRTEDTM":"2022-02-15 01:01:53","TRT01SDTM":"2019-04-27 19:55:31","TRT01EDTM":"2021-02-14 19:01:53","TRT02SDTM":"2021-02-14 19:01:53","TRT02EDTM":"2022-02-15 01:01:53","AP01SDTM":"2019-04-27 19:55:31","AP01EDTM":"2021-02-14 19:01:53","AP02SDTM":"2021-02-14 19:01:53","AP02EDTM":"2022-02-15 01:01:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1025,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-01","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":432,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.17942,"AVALU":"U/L","BASE2":22.17942,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-05-25 19:55:31","ADY":28,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-242","SUBJID":"id-242","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":13.87859,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 19:55:31","TRTEDTM":"2022-02-15 01:01:53","TRT01SDTM":"2019-04-27 19:55:31","TRT01EDTM":"2021-02-14 19:01:53","TRT02SDTM":"2021-02-14 19:01:53","TRT02EDTM":"2022-02-15 01:01:53","AP01SDTM":"2019-04-27 19:55:31","AP01EDTM":"2021-02-14 19:01:53","AP02SDTM":"2021-02-14 19:01:53","AP02EDTM":"2022-02-15 01:01:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1025,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-01","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3244,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.27407,"AVALU":"U/L","BASE2":22.17942,"BASE":17.27407,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-4.90535,"PCHG2":-22.11666,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-11 19:55:31","ADY":350,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-242","SUBJID":"id-242","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":13.87859,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 19:55:31","TRTEDTM":"2022-02-15 01:01:53","TRT01SDTM":"2019-04-27 19:55:31","TRT01EDTM":"2021-02-14 19:01:53","TRT02SDTM":"2021-02-14 19:01:53","TRT02EDTM":"2022-02-15 01:01:53","AP01SDTM":"2019-04-27 19:55:31","AP01EDTM":"2021-02-14 19:01:53","AP02SDTM":"2021-02-14 19:01:53","AP02EDTM":"2022-02-15 01:01:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1025,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-01","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4488,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.25804,"AVALU":"U/L","BASE2":22.17942,"BASE":17.27407,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.07863,"PCHG2":18.38924,"CHG":8.98397,"PCHG":52.00843,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-23 19:55:31","ADY":484,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-242","SUBJID":"id-242","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":13.87859,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 19:55:31","TRTEDTM":"2022-02-15 01:01:53","TRT01SDTM":"2019-04-27 19:55:31","TRT01EDTM":"2021-02-14 19:01:53","TRT02SDTM":"2021-02-14 19:01:53","TRT02EDTM":"2022-02-15 01:01:53","AP01SDTM":"2019-04-27 19:55:31","AP01EDTM":"2021-02-14 19:01:53","AP02SDTM":"2021-02-14 19:01:53","AP02EDTM":"2022-02-15 01:01:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1025,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-01","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4930,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.63485,"AVALU":"U/L","BASE2":22.17942,"BASE":17.27407,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.54456,"PCHG2":-61.06817,"CHG":-8.63922,"PCHG":-50.01263,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-28 19:55:31","ADY":732,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-242","SUBJID":"id-242","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":13.87859,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 19:55:31","TRTEDTM":"2022-02-15 01:01:53","TRT01SDTM":"2019-04-27 19:55:31","TRT01EDTM":"2021-02-14 19:01:53","TRT02SDTM":"2021-02-14 19:01:53","TRT02EDTM":"2022-02-15 01:01:53","AP01SDTM":"2019-04-27 19:55:31","AP01EDTM":"2021-02-14 19:01:53","AP02SDTM":"2021-02-14 19:01:53","AP02EDTM":"2022-02-15 01:01:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1025,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-01","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6757,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.40596,"AVALU":"U/L","BASE2":22.17942,"BASE":17.27407,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.77346,"PCHG2":-53.08282,"CHG":-6.86811,"PCHG":-39.75967,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-03 19:55:31","ADY":860,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-242","SUBJID":"id-242","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":13.87859,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 19:55:31","TRTEDTM":"2022-02-15 01:01:53","TRT01SDTM":"2019-04-27 19:55:31","TRT01EDTM":"2021-02-14 19:01:53","TRT02SDTM":"2021-02-14 19:01:53","TRT02EDTM":"2022-02-15 01:01:53","AP01SDTM":"2019-04-27 19:55:31","AP01EDTM":"2021-02-14 19:01:53","AP02SDTM":"2021-02-14 19:01:53","AP02EDTM":"2022-02-15 01:01:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1025,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-01","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7940,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.84643,"AVALU":"U/L","BASE2":22.17942,"BASE":17.27407,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.33298,"PCHG2":-19.53605,"CHG":0.57236,"PCHG":3.31343,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-11 19:55:31","ADY":990,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-242","SUBJID":"id-242","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":13.87859,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 19:55:31","TRTEDTM":"2022-02-15 01:01:53","TRT01SDTM":"2019-04-27 19:55:31","TRT01EDTM":"2021-02-14 19:01:53","TRT02SDTM":"2021-02-14 19:01:53","TRT02EDTM":"2022-02-15 01:01:53","AP01SDTM":"2019-04-27 19:55:31","AP01EDTM":"2021-02-14 19:01:53","AP02SDTM":"2021-02-14 19:01:53","AP02EDTM":"2022-02-15 01:01:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1025,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-01","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2313,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.53661,"AVALU":"U/L","BASE2":22.17942,"BASE":17.27407,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.3572,"PCHG2":1.61048,"CHG":5.26254,"PCHG":30.46498,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-19 19:55:31","ADY":998,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-242","SUBJID":"id-242","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":13.87859,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 19:55:31","TRTEDTM":"2022-02-15 01:01:53","TRT01SDTM":"2019-04-27 19:55:31","TRT01EDTM":"2021-02-14 19:01:53","TRT02SDTM":"2021-02-14 19:01:53","TRT02EDTM":"2022-02-15 01:01:53","AP01SDTM":"2019-04-27 19:55:31","AP01EDTM":"2021-02-14 19:01:53","AP02SDTM":"2021-02-14 19:01:53","AP02EDTM":"2022-02-15 01:01:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1025,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-01","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2148,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.83426,"AVALU":"mg/L","BASE2":9.83426,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-05-25 19:55:31","ADY":28,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-242","SUBJID":"id-242","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":13.87859,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 19:55:31","TRTEDTM":"2022-02-15 01:01:53","TRT01SDTM":"2019-04-27 19:55:31","TRT01EDTM":"2021-02-14 19:01:53","TRT02SDTM":"2021-02-14 19:01:53","TRT02EDTM":"2022-02-15 01:01:53","AP01SDTM":"2019-04-27 19:55:31","AP01EDTM":"2021-02-14 19:01:53","AP02SDTM":"2021-02-14 19:01:53","AP02EDTM":"2022-02-15 01:01:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1025,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-01","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3569,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.24608,"AVALU":"mg/L","BASE2":9.83426,"BASE":8.24608,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.58818,"PCHG2":-16.14947,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-11 19:55:31","ADY":350,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-242","SUBJID":"id-242","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":13.87859,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 19:55:31","TRTEDTM":"2022-02-15 01:01:53","TRT01SDTM":"2019-04-27 19:55:31","TRT01EDTM":"2021-02-14 19:01:53","TRT02SDTM":"2021-02-14 19:01:53","TRT02EDTM":"2022-02-15 01:01:53","AP01SDTM":"2019-04-27 19:55:31","AP01EDTM":"2021-02-14 19:01:53","AP02SDTM":"2021-02-14 19:01:53","AP02EDTM":"2022-02-15 01:01:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1025,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-01","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":21,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.29658,"AVALU":"mg/L","BASE2":9.83426,"BASE":8.24608,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.46231,"PCHG2":4.70105,"CHG":2.0505,"PCHG":24.8663,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-08-23 19:55:31","ADY":484,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-242","SUBJID":"id-242","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":13.87859,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 19:55:31","TRTEDTM":"2022-02-15 01:01:53","TRT01SDTM":"2019-04-27 19:55:31","TRT01EDTM":"2021-02-14 19:01:53","TRT02SDTM":"2021-02-14 19:01:53","TRT02EDTM":"2022-02-15 01:01:53","AP01SDTM":"2019-04-27 19:55:31","AP01EDTM":"2021-02-14 19:01:53","AP02SDTM":"2021-02-14 19:01:53","AP02EDTM":"2022-02-15 01:01:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1025,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-01","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3831,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.63452,"AVALU":"mg/L","BASE2":9.83426,"BASE":8.24608,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.19974,"PCHG2":-12.19958,"CHG":0.38844,"PCHG":4.71063,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-28 19:55:31","ADY":732,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-242","SUBJID":"id-242","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":13.87859,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 19:55:31","TRTEDTM":"2022-02-15 01:01:53","TRT01SDTM":"2019-04-27 19:55:31","TRT01EDTM":"2021-02-14 19:01:53","TRT02SDTM":"2021-02-14 19:01:53","TRT02EDTM":"2022-02-15 01:01:53","AP01SDTM":"2019-04-27 19:55:31","AP01EDTM":"2021-02-14 19:01:53","AP02SDTM":"2021-02-14 19:01:53","AP02EDTM":"2022-02-15 01:01:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1025,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-01","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7585,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.71983,"AVALU":"mg/L","BASE2":9.83426,"BASE":8.24608,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.11443,"PCHG2":-21.50066,"CHG":-0.52625,"PCHG":-6.38182,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-09-03 19:55:31","ADY":860,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-242","SUBJID":"id-242","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":13.87859,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 19:55:31","TRTEDTM":"2022-02-15 01:01:53","TRT01SDTM":"2019-04-27 19:55:31","TRT01EDTM":"2021-02-14 19:01:53","TRT02SDTM":"2021-02-14 19:01:53","TRT02EDTM":"2022-02-15 01:01:53","AP01SDTM":"2019-04-27 19:55:31","AP01EDTM":"2021-02-14 19:01:53","AP02SDTM":"2021-02-14 19:01:53","AP02EDTM":"2022-02-15 01:01:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1025,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-01","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":342,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.4441,"AVALU":"mg/L","BASE2":9.83426,"BASE":8.24608,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.39016,"PCHG2":-3.96737,"CHG":1.19802,"PCHG":14.52835,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-11 19:55:31","ADY":990,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-242","SUBJID":"id-242","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":13.87859,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 19:55:31","TRTEDTM":"2022-02-15 01:01:53","TRT01SDTM":"2019-04-27 19:55:31","TRT01EDTM":"2021-02-14 19:01:53","TRT02SDTM":"2021-02-14 19:01:53","TRT02EDTM":"2022-02-15 01:01:53","AP01SDTM":"2019-04-27 19:55:31","AP01EDTM":"2021-02-14 19:01:53","AP02SDTM":"2021-02-14 19:01:53","AP02EDTM":"2022-02-15 01:01:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1025,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-01","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4667,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.91976,"AVALU":"mg/L","BASE2":9.83426,"BASE":8.24608,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0855,"PCHG2":0.86942,"CHG":1.67368,"PCHG":20.2967,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-19 19:55:31","ADY":998,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-242","SUBJID":"id-242","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":13.87859,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 19:55:31","TRTEDTM":"2022-02-15 01:01:53","TRT01SDTM":"2019-04-27 19:55:31","TRT01EDTM":"2021-02-14 19:01:53","TRT02SDTM":"2021-02-14 19:01:53","TRT02EDTM":"2022-02-15 01:01:53","AP01SDTM":"2019-04-27 19:55:31","AP01EDTM":"2021-02-14 19:01:53","AP02SDTM":"2021-02-14 19:01:53","AP02EDTM":"2022-02-15 01:01:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1025,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-01","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3235,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98613,"AVALU":"g/L","BASE2":2.98613,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-05-25 19:55:31","ADY":28,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-242","SUBJID":"id-242","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":13.87859,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 19:55:31","TRTEDTM":"2022-02-15 01:01:53","TRT01SDTM":"2019-04-27 19:55:31","TRT01EDTM":"2021-02-14 19:01:53","TRT02SDTM":"2021-02-14 19:01:53","TRT02EDTM":"2022-02-15 01:01:53","AP01SDTM":"2019-04-27 19:55:31","AP01EDTM":"2021-02-14 19:01:53","AP02SDTM":"2021-02-14 19:01:53","AP02EDTM":"2022-02-15 01:01:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1025,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-01","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4478,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82317,"AVALU":"g/L","BASE2":2.98613,"BASE":2.82317,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.16296,"PCHG2":-5.4571,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-11 19:55:31","ADY":350,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-242","SUBJID":"id-242","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":13.87859,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 19:55:31","TRTEDTM":"2022-02-15 01:01:53","TRT01SDTM":"2019-04-27 19:55:31","TRT01EDTM":"2021-02-14 19:01:53","TRT02SDTM":"2021-02-14 19:01:53","TRT02EDTM":"2022-02-15 01:01:53","AP01SDTM":"2019-04-27 19:55:31","AP01EDTM":"2021-02-14 19:01:53","AP02SDTM":"2021-02-14 19:01:53","AP02EDTM":"2022-02-15 01:01:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1025,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-01","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2034,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95518,"AVALU":"g/L","BASE2":2.98613,"BASE":2.82317,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03095,"PCHG2":-1.03631,"CHG":0.13201,"PCHG":4.67596,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-23 19:55:31","ADY":484,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-242","SUBJID":"id-242","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":13.87859,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 19:55:31","TRTEDTM":"2022-02-15 01:01:53","TRT01SDTM":"2019-04-27 19:55:31","TRT01EDTM":"2021-02-14 19:01:53","TRT02SDTM":"2021-02-14 19:01:53","TRT02EDTM":"2022-02-15 01:01:53","AP01SDTM":"2019-04-27 19:55:31","AP01EDTM":"2021-02-14 19:01:53","AP02SDTM":"2021-02-14 19:01:53","AP02EDTM":"2022-02-15 01:01:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1025,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-01","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5704,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89033,"AVALU":"g/L","BASE2":2.98613,"BASE":2.82317,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0958,"PCHG2":-3.20808,"CHG":0.06716,"PCHG":2.37883,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-28 19:55:31","ADY":732,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-242","SUBJID":"id-242","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":13.87859,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 19:55:31","TRTEDTM":"2022-02-15 01:01:53","TRT01SDTM":"2019-04-27 19:55:31","TRT01EDTM":"2021-02-14 19:01:53","TRT02SDTM":"2021-02-14 19:01:53","TRT02EDTM":"2022-02-15 01:01:53","AP01SDTM":"2019-04-27 19:55:31","AP01EDTM":"2021-02-14 19:01:53","AP02SDTM":"2021-02-14 19:01:53","AP02EDTM":"2022-02-15 01:01:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1025,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-01","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2345,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83648,"AVALU":"g/L","BASE2":2.98613,"BASE":2.82317,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14965,"PCHG2":-5.01155,"CHG":0.0133,"PCHG":0.47127,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-03 19:55:31","ADY":860,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-242","SUBJID":"id-242","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":13.87859,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 19:55:31","TRTEDTM":"2022-02-15 01:01:53","TRT01SDTM":"2019-04-27 19:55:31","TRT01EDTM":"2021-02-14 19:01:53","TRT02SDTM":"2021-02-14 19:01:53","TRT02EDTM":"2022-02-15 01:01:53","AP01SDTM":"2019-04-27 19:55:31","AP01EDTM":"2021-02-14 19:01:53","AP02SDTM":"2021-02-14 19:01:53","AP02EDTM":"2022-02-15 01:01:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1025,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-01","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":825,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88061,"AVALU":"g/L","BASE2":2.98613,"BASE":2.82317,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10552,"PCHG2":-3.53377,"CHG":0.05743,"PCHG":2.03435,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-11 19:55:31","ADY":990,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-242","SUBJID":"id-242","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":13.87859,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-25","TRTSDTM":"2019-04-27 19:55:31","TRTEDTM":"2022-02-15 01:01:53","TRT01SDTM":"2019-04-27 19:55:31","TRT01EDTM":"2021-02-14 19:01:53","TRT02SDTM":"2021-02-14 19:01:53","TRT02EDTM":"2022-02-15 01:01:53","AP01SDTM":"2019-04-27 19:55:31","AP01EDTM":"2021-02-14 19:01:53","AP02SDTM":"2021-02-14 19:01:53","AP02EDTM":"2022-02-15 01:01:53","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":1025,"DCSREAS":"ADVERSE EVENT","LSTALVDT":"2022-03-01","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2903,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77686,"AVALU":"g/L","BASE2":2.98613,"BASE":2.82317,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20927,"PCHG2":-7.00791,"CHG":-0.04631,"PCHG":-1.64032,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-19 19:55:31","ADY":998,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-254","SUBJID":"id-254","SITEID":"USA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":2.65998,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-15 15:02:29","TRTEDTM":"2023-09-16 09:02:29","TRT01SDTM":"2020-09-15 15:02:29","TRT01EDTM":"2022-09-16 03:02:29","TRT02SDTM":"2022-09-16 03:02:29","TRT02EDTM":"2023-09-16 09:02:29","AP01SDTM":"2020-09-15 15:02:29","AP01EDTM":"2022-09-16 03:02:29","AP02SDTM":"2022-09-16 03:02:29","AP02EDTM":"2023-09-16 09:02:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5415,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.16025,"AVALU":"U/L","BASE2":13.16025,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-31 15:02:29","ADY":107,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-254","SUBJID":"id-254","SITEID":"USA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":2.65998,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-15 15:02:29","TRTEDTM":"2023-09-16 09:02:29","TRT01SDTM":"2020-09-15 15:02:29","TRT01EDTM":"2022-09-16 03:02:29","TRT02SDTM":"2022-09-16 03:02:29","TRT02EDTM":"2023-09-16 09:02:29","AP01SDTM":"2020-09-15 15:02:29","AP01EDTM":"2022-09-16 03:02:29","AP02SDTM":"2022-09-16 03:02:29","AP02EDTM":"2023-09-16 09:02:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7432,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.11681,"AVALU":"U/L","BASE2":13.16025,"BASE":16.11681,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.95656,"PCHG2":22.46585,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-09 15:02:29","ADY":267,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-254","SUBJID":"id-254","SITEID":"USA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":2.65998,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-15 15:02:29","TRTEDTM":"2023-09-16 09:02:29","TRT01SDTM":"2020-09-15 15:02:29","TRT01EDTM":"2022-09-16 03:02:29","TRT02SDTM":"2022-09-16 03:02:29","TRT02EDTM":"2023-09-16 09:02:29","AP01SDTM":"2020-09-15 15:02:29","AP01EDTM":"2022-09-16 03:02:29","AP02SDTM":"2022-09-16 03:02:29","AP02EDTM":"2023-09-16 09:02:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":669,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.33687,"AVALU":"U/L","BASE2":13.16025,"BASE":16.11681,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17662,"PCHG2":1.34206,"CHG":-2.77994,"PCHG":-17.24872,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-08 15:02:29","ADY":327,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-254","SUBJID":"id-254","SITEID":"USA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":2.65998,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-15 15:02:29","TRTEDTM":"2023-09-16 09:02:29","TRT01SDTM":"2020-09-15 15:02:29","TRT01EDTM":"2022-09-16 03:02:29","TRT02SDTM":"2022-09-16 03:02:29","TRT02EDTM":"2023-09-16 09:02:29","AP01SDTM":"2020-09-15 15:02:29","AP01EDTM":"2022-09-16 03:02:29","AP02SDTM":"2022-09-16 03:02:29","AP02EDTM":"2023-09-16 09:02:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":883,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.45287,"AVALU":"U/L","BASE2":13.16025,"BASE":16.11681,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.70738,"PCHG2":-5.37515,"CHG":-3.66395,"PCHG":-22.73369,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-18 15:02:29","ADY":368,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-254","SUBJID":"id-254","SITEID":"USA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":2.65998,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-15 15:02:29","TRTEDTM":"2023-09-16 09:02:29","TRT01SDTM":"2020-09-15 15:02:29","TRT01EDTM":"2022-09-16 03:02:29","TRT02SDTM":"2022-09-16 03:02:29","TRT02EDTM":"2023-09-16 09:02:29","AP01SDTM":"2020-09-15 15:02:29","AP01EDTM":"2022-09-16 03:02:29","AP02SDTM":"2022-09-16 03:02:29","AP02EDTM":"2023-09-16 09:02:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4196,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.12017,"AVALU":"U/L","BASE2":13.16025,"BASE":16.11681,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.95992,"PCHG2":14.89272,"CHG":-0.99664,"PCHG":-6.18387,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-18 15:02:29","ADY":429,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-254","SUBJID":"id-254","SITEID":"USA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":2.65998,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-15 15:02:29","TRTEDTM":"2023-09-16 09:02:29","TRT01SDTM":"2020-09-15 15:02:29","TRT01EDTM":"2022-09-16 03:02:29","TRT02SDTM":"2022-09-16 03:02:29","TRT02EDTM":"2023-09-16 09:02:29","AP01SDTM":"2020-09-15 15:02:29","AP01EDTM":"2022-09-16 03:02:29","AP02SDTM":"2022-09-16 03:02:29","AP02EDTM":"2023-09-16 09:02:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4414,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.66666,"AVALU":"U/L","BASE2":13.16025,"BASE":16.11681,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.4936,"PCHG2":-56.94113,"CHG":-10.45016,"PCHG":-64.8401,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-12-23 15:02:29","ADY":464,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-254","SUBJID":"id-254","SITEID":"USA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":2.65998,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-15 15:02:29","TRTEDTM":"2023-09-16 09:02:29","TRT01SDTM":"2020-09-15 15:02:29","TRT01EDTM":"2022-09-16 03:02:29","TRT02SDTM":"2022-09-16 03:02:29","TRT02EDTM":"2023-09-16 09:02:29","AP01SDTM":"2020-09-15 15:02:29","AP01EDTM":"2022-09-16 03:02:29","AP02SDTM":"2022-09-16 03:02:29","AP02EDTM":"2023-09-16 09:02:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2720,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.0141,"AVALU":"U/L","BASE2":13.16025,"BASE":16.11681,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.85385,"PCHG2":90.07313,"CHG":8.89729,"PCHG":55.205,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-18 15:02:29","ADY":580,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-254","SUBJID":"id-254","SITEID":"USA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":2.65998,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-15 15:02:29","TRTEDTM":"2023-09-16 09:02:29","TRT01SDTM":"2020-09-15 15:02:29","TRT01EDTM":"2022-09-16 03:02:29","TRT02SDTM":"2022-09-16 03:02:29","TRT02EDTM":"2023-09-16 09:02:29","AP01SDTM":"2020-09-15 15:02:29","AP01EDTM":"2022-09-16 03:02:29","AP02SDTM":"2022-09-16 03:02:29","AP02EDTM":"2023-09-16 09:02:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3319,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.40772,"AVALU":"mg/L","BASE2":8.40772,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-31 15:02:29","ADY":107,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-254","SUBJID":"id-254","SITEID":"USA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":2.65998,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-15 15:02:29","TRTEDTM":"2023-09-16 09:02:29","TRT01SDTM":"2020-09-15 15:02:29","TRT01EDTM":"2022-09-16 03:02:29","TRT02SDTM":"2022-09-16 03:02:29","TRT02EDTM":"2023-09-16 09:02:29","AP01SDTM":"2020-09-15 15:02:29","AP01EDTM":"2022-09-16 03:02:29","AP02SDTM":"2022-09-16 03:02:29","AP02EDTM":"2023-09-16 09:02:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4955,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.11717,"AVALU":"mg/L","BASE2":8.40772,"BASE":9.11717,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.70945,"PCHG2":8.43804,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-09 15:02:29","ADY":267,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-254","SUBJID":"id-254","SITEID":"USA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":2.65998,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-15 15:02:29","TRTEDTM":"2023-09-16 09:02:29","TRT01SDTM":"2020-09-15 15:02:29","TRT01EDTM":"2022-09-16 03:02:29","TRT02SDTM":"2022-09-16 03:02:29","TRT02EDTM":"2023-09-16 09:02:29","AP01SDTM":"2020-09-15 15:02:29","AP01EDTM":"2022-09-16 03:02:29","AP02SDTM":"2022-09-16 03:02:29","AP02EDTM":"2023-09-16 09:02:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":673,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.58268,"AVALU":"mg/L","BASE2":8.40772,"BASE":9.11717,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17495,"PCHG2":2.08088,"CHG":-0.53449,"PCHG":-5.86248,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-08 15:02:29","ADY":327,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-254","SUBJID":"id-254","SITEID":"USA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":2.65998,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-15 15:02:29","TRTEDTM":"2023-09-16 09:02:29","TRT01SDTM":"2020-09-15 15:02:29","TRT01EDTM":"2022-09-16 03:02:29","TRT02SDTM":"2022-09-16 03:02:29","TRT02EDTM":"2023-09-16 09:02:29","AP01SDTM":"2020-09-15 15:02:29","AP01EDTM":"2022-09-16 03:02:29","AP02SDTM":"2022-09-16 03:02:29","AP02EDTM":"2023-09-16 09:02:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2291,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.35524,"AVALU":"mg/L","BASE2":8.40772,"BASE":9.11717,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05248,"PCHG2":-0.6242,"CHG":-0.76193,"PCHG":-8.35707,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-18 15:02:29","ADY":368,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-254","SUBJID":"id-254","SITEID":"USA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":2.65998,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-15 15:02:29","TRTEDTM":"2023-09-16 09:02:29","TRT01SDTM":"2020-09-15 15:02:29","TRT01EDTM":"2022-09-16 03:02:29","TRT02SDTM":"2022-09-16 03:02:29","TRT02EDTM":"2023-09-16 09:02:29","AP01SDTM":"2020-09-15 15:02:29","AP01EDTM":"2022-09-16 03:02:29","AP02SDTM":"2022-09-16 03:02:29","AP02EDTM":"2023-09-16 09:02:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2423,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.66618,"AVALU":"mg/L","BASE2":8.40772,"BASE":9.11717,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.25846,"PCHG2":3.07404,"CHG":-0.45099,"PCHG":-4.94661,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-18 15:02:29","ADY":429,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-254","SUBJID":"id-254","SITEID":"USA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":2.65998,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-15 15:02:29","TRTEDTM":"2023-09-16 09:02:29","TRT01SDTM":"2020-09-15 15:02:29","TRT01EDTM":"2022-09-16 03:02:29","TRT02SDTM":"2022-09-16 03:02:29","TRT02EDTM":"2023-09-16 09:02:29","AP01SDTM":"2020-09-15 15:02:29","AP01EDTM":"2022-09-16 03:02:29","AP02SDTM":"2022-09-16 03:02:29","AP02EDTM":"2023-09-16 09:02:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":40,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.21547,"AVALU":"mg/L","BASE2":8.40772,"BASE":9.11717,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19225,"PCHG2":-2.28658,"CHG":-0.9017,"PCHG":-9.89009,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-23 15:02:29","ADY":464,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-254","SUBJID":"id-254","SITEID":"USA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":2.65998,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-15 15:02:29","TRTEDTM":"2023-09-16 09:02:29","TRT01SDTM":"2020-09-15 15:02:29","TRT01EDTM":"2022-09-16 03:02:29","TRT02SDTM":"2022-09-16 03:02:29","TRT02EDTM":"2023-09-16 09:02:29","AP01SDTM":"2020-09-15 15:02:29","AP01EDTM":"2022-09-16 03:02:29","AP02SDTM":"2022-09-16 03:02:29","AP02EDTM":"2023-09-16 09:02:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3692,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.80538,"AVALU":"mg/L","BASE2":8.40772,"BASE":9.11717,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.39765,"PCHG2":4.72963,"CHG":-0.31179,"PCHG":-3.41984,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-18 15:02:29","ADY":580,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-254","SUBJID":"id-254","SITEID":"USA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":2.65998,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-15 15:02:29","TRTEDTM":"2023-09-16 09:02:29","TRT01SDTM":"2020-09-15 15:02:29","TRT01EDTM":"2022-09-16 03:02:29","TRT02SDTM":"2022-09-16 03:02:29","TRT02EDTM":"2023-09-16 09:02:29","AP01SDTM":"2020-09-15 15:02:29","AP01EDTM":"2022-09-16 03:02:29","AP02SDTM":"2022-09-16 03:02:29","AP02EDTM":"2023-09-16 09:02:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4899,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98983,"AVALU":"g/L","BASE2":2.98983,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-31 15:02:29","ADY":107,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-254","SUBJID":"id-254","SITEID":"USA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":2.65998,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-15 15:02:29","TRTEDTM":"2023-09-16 09:02:29","TRT01SDTM":"2020-09-15 15:02:29","TRT01EDTM":"2022-09-16 03:02:29","TRT02SDTM":"2022-09-16 03:02:29","TRT02EDTM":"2023-09-16 09:02:29","AP01SDTM":"2020-09-15 15:02:29","AP01EDTM":"2022-09-16 03:02:29","AP02SDTM":"2022-09-16 03:02:29","AP02EDTM":"2023-09-16 09:02:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4666,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97661,"AVALU":"g/L","BASE2":2.98983,"BASE":2.97661,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.01322,"PCHG2":-0.44214,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-09 15:02:29","ADY":267,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-254","SUBJID":"id-254","SITEID":"USA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":2.65998,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-15 15:02:29","TRTEDTM":"2023-09-16 09:02:29","TRT01SDTM":"2020-09-15 15:02:29","TRT01EDTM":"2022-09-16 03:02:29","TRT02SDTM":"2022-09-16 03:02:29","TRT02EDTM":"2023-09-16 09:02:29","AP01SDTM":"2020-09-15 15:02:29","AP01EDTM":"2022-09-16 03:02:29","AP02SDTM":"2022-09-16 03:02:29","AP02EDTM":"2023-09-16 09:02:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7637,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94398,"AVALU":"g/L","BASE2":2.98983,"BASE":2.97661,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04585,"PCHG2":-1.53345,"CHG":-0.03263,"PCHG":-1.09615,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-08 15:02:29","ADY":327,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-254","SUBJID":"id-254","SITEID":"USA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":2.65998,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-15 15:02:29","TRTEDTM":"2023-09-16 09:02:29","TRT01SDTM":"2020-09-15 15:02:29","TRT01EDTM":"2022-09-16 03:02:29","TRT02SDTM":"2022-09-16 03:02:29","TRT02EDTM":"2023-09-16 09:02:29","AP01SDTM":"2020-09-15 15:02:29","AP01EDTM":"2022-09-16 03:02:29","AP02SDTM":"2022-09-16 03:02:29","AP02EDTM":"2023-09-16 09:02:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7789,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81275,"AVALU":"g/L","BASE2":2.98983,"BASE":2.97661,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17707,"PCHG2":-5.92252,"CHG":-0.16385,"PCHG":-5.50473,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-18 15:02:29","ADY":368,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-254","SUBJID":"id-254","SITEID":"USA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":2.65998,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-15 15:02:29","TRTEDTM":"2023-09-16 09:02:29","TRT01SDTM":"2020-09-15 15:02:29","TRT01EDTM":"2022-09-16 03:02:29","TRT02SDTM":"2022-09-16 03:02:29","TRT02EDTM":"2023-09-16 09:02:29","AP01SDTM":"2020-09-15 15:02:29","AP01EDTM":"2022-09-16 03:02:29","AP02SDTM":"2022-09-16 03:02:29","AP02EDTM":"2023-09-16 09:02:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1202,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9303,"AVALU":"g/L","BASE2":2.98983,"BASE":2.97661,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05952,"PCHG2":-1.99092,"CHG":-0.04631,"PCHG":-1.55566,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-18 15:02:29","ADY":429,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-254","SUBJID":"id-254","SITEID":"USA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":2.65998,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-15 15:02:29","TRTEDTM":"2023-09-16 09:02:29","TRT01SDTM":"2020-09-15 15:02:29","TRT01EDTM":"2022-09-16 03:02:29","TRT02SDTM":"2022-09-16 03:02:29","TRT02EDTM":"2023-09-16 09:02:29","AP01SDTM":"2020-09-15 15:02:29","AP01EDTM":"2022-09-16 03:02:29","AP02SDTM":"2022-09-16 03:02:29","AP02EDTM":"2023-09-16 09:02:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6666,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79994,"AVALU":"g/L","BASE2":2.98983,"BASE":2.97661,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18988,"PCHG2":-6.35092,"CHG":-0.17666,"PCHG":-5.93502,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-23 15:02:29","ADY":464,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-254","SUBJID":"id-254","SITEID":"USA-1","AGE":28,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":2.65998,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-13","TRTSDTM":"2020-09-15 15:02:29","TRTEDTM":"2023-09-16 09:02:29","TRT01SDTM":"2020-09-15 15:02:29","TRT01EDTM":"2022-09-16 03:02:29","TRT02SDTM":"2022-09-16 03:02:29","TRT02EDTM":"2023-09-16 09:02:29","AP01SDTM":"2020-09-15 15:02:29","AP01EDTM":"2022-09-16 03:02:29","AP02SDTM":"2022-09-16 03:02:29","AP02EDTM":"2023-09-16 09:02:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-09-16","EOSDY":1096,"LSTALVDT":"2023-10-14","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3572,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92349,"AVALU":"g/L","BASE2":2.98983,"BASE":2.97661,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06634,"PCHG2":-2.21875,"CHG":-0.05312,"PCHG":-1.7845,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-18 15:02:29","ADY":580,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-261","SUBJID":"id-261","SITEID":"USA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.85516,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-02","TRTSDTM":"2019-03-06 17:21:21","TRTEDTM":"2022-03-06 11:21:21","TRT01SDTM":"2019-03-06 17:21:21","TRT01EDTM":"2021-03-06 05:21:21","TRT02SDTM":"2021-03-06 05:21:21","TRT02EDTM":"2022-03-06 11:21:21","AP01SDTM":"2019-03-06 17:21:21","AP01EDTM":"2021-03-06 05:21:21","AP02SDTM":"2021-03-06 05:21:21","AP02EDTM":"2022-03-06 11:21:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1526,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.38325,"AVALU":"U/L","BASE2":25.38325,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-01 17:21:21","ADY":270,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-261","SUBJID":"id-261","SITEID":"USA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.85516,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-02","TRTSDTM":"2019-03-06 17:21:21","TRTEDTM":"2022-03-06 11:21:21","TRT01SDTM":"2019-03-06 17:21:21","TRT01EDTM":"2021-03-06 05:21:21","TRT02SDTM":"2021-03-06 05:21:21","TRT02EDTM":"2022-03-06 11:21:21","AP01SDTM":"2019-03-06 17:21:21","AP01EDTM":"2021-03-06 05:21:21","AP02SDTM":"2021-03-06 05:21:21","AP02EDTM":"2022-03-06 11:21:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1461,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.9318,"AVALU":"U/L","BASE2":25.38325,"BASE":15.9318,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-9.45145,"PCHG2":-37.235,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-22 17:21:21","ADY":322,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-261","SUBJID":"id-261","SITEID":"USA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.85516,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-02","TRTSDTM":"2019-03-06 17:21:21","TRTEDTM":"2022-03-06 11:21:21","TRT01SDTM":"2019-03-06 17:21:21","TRT01EDTM":"2021-03-06 05:21:21","TRT02SDTM":"2021-03-06 05:21:21","TRT02EDTM":"2022-03-06 11:21:21","AP01SDTM":"2019-03-06 17:21:21","AP01EDTM":"2021-03-06 05:21:21","AP02SDTM":"2021-03-06 05:21:21","AP02EDTM":"2022-03-06 11:21:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3644,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.18398,"AVALU":"U/L","BASE2":25.38325,"BASE":15.9318,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.19927,"PCHG2":-8.66425,"CHG":7.25218,"PCHG":45.52019,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-17 17:21:21","ADY":683,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-261","SUBJID":"id-261","SITEID":"USA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.85516,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-02","TRTSDTM":"2019-03-06 17:21:21","TRTEDTM":"2022-03-06 11:21:21","TRT01SDTM":"2019-03-06 17:21:21","TRT01EDTM":"2021-03-06 05:21:21","TRT02SDTM":"2021-03-06 05:21:21","TRT02EDTM":"2022-03-06 11:21:21","AP01SDTM":"2019-03-06 17:21:21","AP01EDTM":"2021-03-06 05:21:21","AP02SDTM":"2021-03-06 05:21:21","AP02EDTM":"2022-03-06 11:21:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8254,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.99123,"AVALU":"U/L","BASE2":25.38325,"BASE":15.9318,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.39202,"PCHG2":-29.12165,"CHG":2.05943,"PCHG":12.92654,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-19 17:21:21","ADY":716,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-261","SUBJID":"id-261","SITEID":"USA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.85516,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-02","TRTSDTM":"2019-03-06 17:21:21","TRTEDTM":"2022-03-06 11:21:21","TRT01SDTM":"2019-03-06 17:21:21","TRT01EDTM":"2021-03-06 05:21:21","TRT02SDTM":"2021-03-06 05:21:21","TRT02EDTM":"2022-03-06 11:21:21","AP01SDTM":"2019-03-06 17:21:21","AP01EDTM":"2021-03-06 05:21:21","AP02SDTM":"2021-03-06 05:21:21","AP02EDTM":"2022-03-06 11:21:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4720,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.29277,"AVALU":"U/L","BASE2":25.38325,"BASE":15.9318,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.90952,"PCHG2":7.52276,"CHG":11.36097,"PCHG":71.31006,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-17 17:21:21","ADY":773,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-261","SUBJID":"id-261","SITEID":"USA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.85516,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-02","TRTSDTM":"2019-03-06 17:21:21","TRTEDTM":"2022-03-06 11:21:21","TRT01SDTM":"2019-03-06 17:21:21","TRT01EDTM":"2021-03-06 05:21:21","TRT02SDTM":"2021-03-06 05:21:21","TRT02EDTM":"2022-03-06 11:21:21","AP01SDTM":"2019-03-06 17:21:21","AP01EDTM":"2021-03-06 05:21:21","AP02SDTM":"2021-03-06 05:21:21","AP02EDTM":"2022-03-06 11:21:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7646,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.0837,"AVALU":"U/L","BASE2":25.38325,"BASE":15.9318,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.70045,"PCHG2":34.27637,"CHG":18.15191,"PCHG":113.9351,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-14 17:21:21","ADY":923,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-261","SUBJID":"id-261","SITEID":"USA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.85516,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-02","TRTSDTM":"2019-03-06 17:21:21","TRTEDTM":"2022-03-06 11:21:21","TRT01SDTM":"2019-03-06 17:21:21","TRT01EDTM":"2021-03-06 05:21:21","TRT02SDTM":"2021-03-06 05:21:21","TRT02EDTM":"2022-03-06 11:21:21","AP01SDTM":"2019-03-06 17:21:21","AP01EDTM":"2021-03-06 05:21:21","AP02SDTM":"2021-03-06 05:21:21","AP02EDTM":"2022-03-06 11:21:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5382,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.68111,"AVALU":"U/L","BASE2":25.38325,"BASE":15.9318,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.70214,"PCHG2":-6.70575,"CHG":7.74932,"PCHG":48.64057,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-23 17:21:21","ADY":1085,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-261","SUBJID":"id-261","SITEID":"USA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.85516,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-02","TRTSDTM":"2019-03-06 17:21:21","TRTEDTM":"2022-03-06 11:21:21","TRT01SDTM":"2019-03-06 17:21:21","TRT01EDTM":"2021-03-06 05:21:21","TRT02SDTM":"2021-03-06 05:21:21","TRT02EDTM":"2022-03-06 11:21:21","AP01SDTM":"2019-03-06 17:21:21","AP01EDTM":"2021-03-06 05:21:21","AP02SDTM":"2021-03-06 05:21:21","AP02EDTM":"2022-03-06 11:21:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8121,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.97874,"AVALU":"mg/L","BASE2":8.97874,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-01 17:21:21","ADY":270,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-261","SUBJID":"id-261","SITEID":"USA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.85516,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-02","TRTSDTM":"2019-03-06 17:21:21","TRTEDTM":"2022-03-06 11:21:21","TRT01SDTM":"2019-03-06 17:21:21","TRT01EDTM":"2021-03-06 05:21:21","TRT02SDTM":"2021-03-06 05:21:21","TRT02EDTM":"2022-03-06 11:21:21","AP01SDTM":"2019-03-06 17:21:21","AP01EDTM":"2021-03-06 05:21:21","AP02SDTM":"2021-03-06 05:21:21","AP02EDTM":"2022-03-06 11:21:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7725,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.47197,"AVALU":"mg/L","BASE2":8.97874,"BASE":9.47197,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.49323,"PCHG2":5.49327,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-22 17:21:21","ADY":322,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-261","SUBJID":"id-261","SITEID":"USA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.85516,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-02","TRTSDTM":"2019-03-06 17:21:21","TRTEDTM":"2022-03-06 11:21:21","TRT01SDTM":"2019-03-06 17:21:21","TRT01EDTM":"2021-03-06 05:21:21","TRT02SDTM":"2021-03-06 05:21:21","TRT02EDTM":"2022-03-06 11:21:21","AP01SDTM":"2019-03-06 17:21:21","AP01EDTM":"2021-03-06 05:21:21","AP02SDTM":"2021-03-06 05:21:21","AP02EDTM":"2022-03-06 11:21:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4596,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.39767,"AVALU":"mg/L","BASE2":8.97874,"BASE":9.47197,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.41893,"PCHG2":4.66577,"CHG":-0.0743,"PCHG":-0.78441,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-17 17:21:21","ADY":683,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-261","SUBJID":"id-261","SITEID":"USA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.85516,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-02","TRTSDTM":"2019-03-06 17:21:21","TRTEDTM":"2022-03-06 11:21:21","TRT01SDTM":"2019-03-06 17:21:21","TRT01EDTM":"2021-03-06 05:21:21","TRT02SDTM":"2021-03-06 05:21:21","TRT02EDTM":"2022-03-06 11:21:21","AP01SDTM":"2019-03-06 17:21:21","AP01EDTM":"2021-03-06 05:21:21","AP02SDTM":"2021-03-06 05:21:21","AP02EDTM":"2022-03-06 11:21:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5549,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.44696,"AVALU":"mg/L","BASE2":8.97874,"BASE":9.47197,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.53178,"PCHG2":-5.92267,"CHG":-1.02501,"PCHG":-10.82149,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-19 17:21:21","ADY":716,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-261","SUBJID":"id-261","SITEID":"USA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.85516,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-02","TRTSDTM":"2019-03-06 17:21:21","TRTEDTM":"2022-03-06 11:21:21","TRT01SDTM":"2019-03-06 17:21:21","TRT01EDTM":"2021-03-06 05:21:21","TRT02SDTM":"2021-03-06 05:21:21","TRT02EDTM":"2022-03-06 11:21:21","AP01SDTM":"2019-03-06 17:21:21","AP01EDTM":"2021-03-06 05:21:21","AP02SDTM":"2021-03-06 05:21:21","AP02EDTM":"2022-03-06 11:21:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6361,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.68841,"AVALU":"mg/L","BASE2":8.97874,"BASE":9.47197,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.29033,"PCHG2":-3.23354,"CHG":-0.78356,"PCHG":-8.27239,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-17 17:21:21","ADY":773,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-261","SUBJID":"id-261","SITEID":"USA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.85516,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-02","TRTSDTM":"2019-03-06 17:21:21","TRTEDTM":"2022-03-06 11:21:21","TRT01SDTM":"2019-03-06 17:21:21","TRT01EDTM":"2021-03-06 05:21:21","TRT02SDTM":"2021-03-06 05:21:21","TRT02EDTM":"2022-03-06 11:21:21","AP01SDTM":"2019-03-06 17:21:21","AP01EDTM":"2021-03-06 05:21:21","AP02SDTM":"2021-03-06 05:21:21","AP02EDTM":"2022-03-06 11:21:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2842,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.88145,"AVALU":"mg/L","BASE2":8.97874,"BASE":9.47197,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.09729,"PCHG2":-12.22098,"CHG":-1.59052,"PCHG":-16.79183,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-09-14 17:21:21","ADY":923,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-261","SUBJID":"id-261","SITEID":"USA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.85516,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-02","TRTSDTM":"2019-03-06 17:21:21","TRTEDTM":"2022-03-06 11:21:21","TRT01SDTM":"2019-03-06 17:21:21","TRT01EDTM":"2021-03-06 05:21:21","TRT02SDTM":"2021-03-06 05:21:21","TRT02EDTM":"2022-03-06 11:21:21","AP01SDTM":"2019-03-06 17:21:21","AP01EDTM":"2021-03-06 05:21:21","AP02SDTM":"2021-03-06 05:21:21","AP02EDTM":"2022-03-06 11:21:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":347,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.53324,"AVALU":"mg/L","BASE2":8.97874,"BASE":9.47197,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.4455,"PCHG2":-4.96176,"CHG":-0.93873,"PCHG":-9.91061,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-23 17:21:21","ADY":1085,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-261","SUBJID":"id-261","SITEID":"USA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.85516,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-02","TRTSDTM":"2019-03-06 17:21:21","TRTEDTM":"2022-03-06 11:21:21","TRT01SDTM":"2019-03-06 17:21:21","TRT01EDTM":"2021-03-06 05:21:21","TRT02SDTM":"2021-03-06 05:21:21","TRT02EDTM":"2022-03-06 11:21:21","AP01SDTM":"2019-03-06 17:21:21","AP01EDTM":"2021-03-06 05:21:21","AP02SDTM":"2021-03-06 05:21:21","AP02EDTM":"2022-03-06 11:21:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8107,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96005,"AVALU":"g/L","BASE2":2.96005,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-01 17:21:21","ADY":270,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-261","SUBJID":"id-261","SITEID":"USA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.85516,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-02","TRTSDTM":"2019-03-06 17:21:21","TRTEDTM":"2022-03-06 11:21:21","TRT01SDTM":"2019-03-06 17:21:21","TRT01EDTM":"2021-03-06 05:21:21","TRT02SDTM":"2021-03-06 05:21:21","TRT02EDTM":"2022-03-06 11:21:21","AP01SDTM":"2019-03-06 17:21:21","AP01EDTM":"2021-03-06 05:21:21","AP02SDTM":"2021-03-06 05:21:21","AP02EDTM":"2022-03-06 11:21:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6101,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.77644,"AVALU":"g/L","BASE2":2.96005,"BASE":2.77644,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.18361,"PCHG2":-6.20292,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-22 17:21:21","ADY":322,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-261","SUBJID":"id-261","SITEID":"USA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.85516,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-02","TRTSDTM":"2019-03-06 17:21:21","TRTEDTM":"2022-03-06 11:21:21","TRT01SDTM":"2019-03-06 17:21:21","TRT01EDTM":"2021-03-06 05:21:21","TRT02SDTM":"2021-03-06 05:21:21","TRT02EDTM":"2022-03-06 11:21:21","AP01SDTM":"2019-03-06 17:21:21","AP01EDTM":"2021-03-06 05:21:21","AP02SDTM":"2021-03-06 05:21:21","AP02EDTM":"2022-03-06 11:21:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3192,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97232,"AVALU":"g/L","BASE2":2.96005,"BASE":2.77644,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01227,"PCHG2":0.41454,"CHG":0.19588,"PCHG":7.05508,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-17 17:21:21","ADY":683,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-261","SUBJID":"id-261","SITEID":"USA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.85516,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-02","TRTSDTM":"2019-03-06 17:21:21","TRTEDTM":"2022-03-06 11:21:21","TRT01SDTM":"2019-03-06 17:21:21","TRT01EDTM":"2021-03-06 05:21:21","TRT02SDTM":"2021-03-06 05:21:21","TRT02EDTM":"2022-03-06 11:21:21","AP01SDTM":"2019-03-06 17:21:21","AP01EDTM":"2021-03-06 05:21:21","AP02SDTM":"2021-03-06 05:21:21","AP02EDTM":"2022-03-06 11:21:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7684,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93305,"AVALU":"g/L","BASE2":2.96005,"BASE":2.77644,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02699,"PCHG2":-0.91196,"CHG":0.15661,"PCHG":5.64086,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-19 17:21:21","ADY":716,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-261","SUBJID":"id-261","SITEID":"USA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.85516,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-02","TRTSDTM":"2019-03-06 17:21:21","TRTEDTM":"2022-03-06 11:21:21","TRT01SDTM":"2019-03-06 17:21:21","TRT01EDTM":"2021-03-06 05:21:21","TRT02SDTM":"2021-03-06 05:21:21","TRT02EDTM":"2022-03-06 11:21:21","AP01SDTM":"2019-03-06 17:21:21","AP01EDTM":"2021-03-06 05:21:21","AP02SDTM":"2021-03-06 05:21:21","AP02EDTM":"2022-03-06 11:21:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":113,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91032,"AVALU":"g/L","BASE2":2.96005,"BASE":2.77644,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04973,"PCHG2":-1.68013,"CHG":0.13388,"PCHG":4.82189,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-17 17:21:21","ADY":773,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-261","SUBJID":"id-261","SITEID":"USA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.85516,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-02","TRTSDTM":"2019-03-06 17:21:21","TRTEDTM":"2022-03-06 11:21:21","TRT01SDTM":"2019-03-06 17:21:21","TRT01EDTM":"2021-03-06 05:21:21","TRT02SDTM":"2021-03-06 05:21:21","TRT02EDTM":"2022-03-06 11:21:21","AP01SDTM":"2019-03-06 17:21:21","AP01EDTM":"2021-03-06 05:21:21","AP02SDTM":"2021-03-06 05:21:21","AP02EDTM":"2022-03-06 11:21:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1168,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96097,"AVALU":"g/L","BASE2":2.96005,"BASE":2.77644,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00092,"PCHG2":0.03122,"CHG":0.18453,"PCHG":6.64641,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-14 17:21:21","ADY":923,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-261","SUBJID":"id-261","SITEID":"USA-1","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":2.85516,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-02","TRTSDTM":"2019-03-06 17:21:21","TRTEDTM":"2022-03-06 11:21:21","TRT01SDTM":"2019-03-06 17:21:21","TRT01EDTM":"2021-03-06 05:21:21","TRT02SDTM":"2021-03-06 05:21:21","TRT02EDTM":"2022-03-06 11:21:21","AP01SDTM":"2019-03-06 17:21:21","AP01EDTM":"2021-03-06 05:21:21","AP02SDTM":"2021-03-06 05:21:21","AP02EDTM":"2022-03-06 11:21:21","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1491,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87181,"AVALU":"g/L","BASE2":2.96005,"BASE":2.77644,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08824,"PCHG2":-2.98103,"CHG":0.09537,"PCHG":3.43496,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-23 17:21:21","ADY":1085,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-269","SUBJID":"id-269","SITEID":"USA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54767,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-17 11:14:23","TRTEDTM":"2022-05-17 05:14:23","TRT01SDTM":"2019-05-17 11:14:23","TRT01EDTM":"2021-05-16 23:14:23","TRT02SDTM":"2021-05-16 23:14:23","TRT02EDTM":"2022-05-17 05:14:23","AP01SDTM":"2019-05-17 11:14:23","AP01EDTM":"2021-05-16 23:14:23","AP02SDTM":"2021-05-16 23:14:23","AP02EDTM":"2022-05-17 05:14:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-17","EOSDY":1096,"LSTALVDT":"2022-06-09","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3813,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.56663,"AVALU":"U/L","BASE2":23.56663,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-09 11:14:23","ADY":53,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-269","SUBJID":"id-269","SITEID":"USA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54767,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-17 11:14:23","TRTEDTM":"2022-05-17 05:14:23","TRT01SDTM":"2019-05-17 11:14:23","TRT01EDTM":"2021-05-16 23:14:23","TRT02SDTM":"2021-05-16 23:14:23","TRT02EDTM":"2022-05-17 05:14:23","AP01SDTM":"2019-05-17 11:14:23","AP01EDTM":"2021-05-16 23:14:23","AP02SDTM":"2021-05-16 23:14:23","AP02EDTM":"2022-05-17 05:14:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-17","EOSDY":1096,"LSTALVDT":"2022-06-09","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":813,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.15194,"AVALU":"U/L","BASE2":23.56663,"BASE":8.15194,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-15.41469,"PCHG2":-65.40899,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-10 11:14:23","ADY":54,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-269","SUBJID":"id-269","SITEID":"USA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54767,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-17 11:14:23","TRTEDTM":"2022-05-17 05:14:23","TRT01SDTM":"2019-05-17 11:14:23","TRT01EDTM":"2021-05-16 23:14:23","TRT02SDTM":"2021-05-16 23:14:23","TRT02EDTM":"2022-05-17 05:14:23","AP01SDTM":"2019-05-17 11:14:23","AP01EDTM":"2021-05-16 23:14:23","AP02SDTM":"2021-05-16 23:14:23","AP02EDTM":"2022-05-17 05:14:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-17","EOSDY":1096,"LSTALVDT":"2022-06-09","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1495,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.20948,"AVALU":"U/L","BASE2":23.56663,"BASE":8.15194,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.64285,"PCHG2":32.43081,"CHG":23.05754,"PCHG":282.84743,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-26 11:14:23","ADY":436,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-269","SUBJID":"id-269","SITEID":"USA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54767,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-17 11:14:23","TRTEDTM":"2022-05-17 05:14:23","TRT01SDTM":"2019-05-17 11:14:23","TRT01EDTM":"2021-05-16 23:14:23","TRT02SDTM":"2021-05-16 23:14:23","TRT02EDTM":"2022-05-17 05:14:23","AP01SDTM":"2019-05-17 11:14:23","AP01EDTM":"2021-05-16 23:14:23","AP02SDTM":"2021-05-16 23:14:23","AP02EDTM":"2022-05-17 05:14:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-17","EOSDY":1096,"LSTALVDT":"2022-06-09","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4607,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.39998,"AVALU":"U/L","BASE2":23.56663,"BASE":8.15194,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.16666,"PCHG2":-38.89676,"CHG":6.24804,"PCHG":76.64483,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-28 11:14:23","ADY":530,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-269","SUBJID":"id-269","SITEID":"USA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54767,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-17 11:14:23","TRTEDTM":"2022-05-17 05:14:23","TRT01SDTM":"2019-05-17 11:14:23","TRT01EDTM":"2021-05-16 23:14:23","TRT02SDTM":"2021-05-16 23:14:23","TRT02EDTM":"2022-05-17 05:14:23","AP01SDTM":"2019-05-17 11:14:23","AP01EDTM":"2021-05-16 23:14:23","AP02SDTM":"2021-05-16 23:14:23","AP02EDTM":"2022-05-17 05:14:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-17","EOSDY":1096,"LSTALVDT":"2022-06-09","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2688,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.43381,"AVALU":"U/L","BASE2":23.56663,"BASE":8.15194,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.86718,"PCHG2":3.67967,"CHG":16.28187,"PCHG":199.73008,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-19 11:14:23","ADY":794,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-269","SUBJID":"id-269","SITEID":"USA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54767,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-17 11:14:23","TRTEDTM":"2022-05-17 05:14:23","TRT01SDTM":"2019-05-17 11:14:23","TRT01EDTM":"2021-05-16 23:14:23","TRT02SDTM":"2021-05-16 23:14:23","TRT02EDTM":"2022-05-17 05:14:23","AP01SDTM":"2019-05-17 11:14:23","AP01EDTM":"2021-05-16 23:14:23","AP02SDTM":"2021-05-16 23:14:23","AP02EDTM":"2022-05-17 05:14:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-17","EOSDY":1096,"LSTALVDT":"2022-06-09","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":427,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.89577,"AVALU":"U/L","BASE2":23.56663,"BASE":8.15194,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-21.67086,"PCHG2":-91.95571,"CHG":-6.25617,"PCHG":-76.74457,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-08-22 11:14:23","ADY":828,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-269","SUBJID":"id-269","SITEID":"USA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54767,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-17 11:14:23","TRTEDTM":"2022-05-17 05:14:23","TRT01SDTM":"2019-05-17 11:14:23","TRT01EDTM":"2021-05-16 23:14:23","TRT02SDTM":"2021-05-16 23:14:23","TRT02EDTM":"2022-05-17 05:14:23","AP01SDTM":"2019-05-17 11:14:23","AP01EDTM":"2021-05-16 23:14:23","AP02SDTM":"2021-05-16 23:14:23","AP02EDTM":"2022-05-17 05:14:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-17","EOSDY":1096,"LSTALVDT":"2022-06-09","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5988,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.0605,"AVALU":"U/L","BASE2":23.56663,"BASE":8.15194,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.50613,"PCHG2":-40.33725,"CHG":5.90856,"PCHG":72.4805,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-02 11:14:23","ADY":992,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-269","SUBJID":"id-269","SITEID":"USA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54767,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-17 11:14:23","TRTEDTM":"2022-05-17 05:14:23","TRT01SDTM":"2019-05-17 11:14:23","TRT01EDTM":"2021-05-16 23:14:23","TRT02SDTM":"2021-05-16 23:14:23","TRT02EDTM":"2022-05-17 05:14:23","AP01SDTM":"2019-05-17 11:14:23","AP01EDTM":"2021-05-16 23:14:23","AP02SDTM":"2021-05-16 23:14:23","AP02EDTM":"2022-05-17 05:14:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-17","EOSDY":1096,"LSTALVDT":"2022-06-09","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5889,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.98105,"AVALU":"mg/L","BASE2":7.98105,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2019-07-09 11:14:23","ADY":53,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-269","SUBJID":"id-269","SITEID":"USA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54767,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-17 11:14:23","TRTEDTM":"2022-05-17 05:14:23","TRT01SDTM":"2019-05-17 11:14:23","TRT01EDTM":"2021-05-16 23:14:23","TRT02SDTM":"2021-05-16 23:14:23","TRT02EDTM":"2022-05-17 05:14:23","AP01SDTM":"2019-05-17 11:14:23","AP01EDTM":"2021-05-16 23:14:23","AP02SDTM":"2021-05-16 23:14:23","AP02EDTM":"2022-05-17 05:14:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-17","EOSDY":1096,"LSTALVDT":"2022-06-09","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8019,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.75552,"AVALU":"mg/L","BASE2":7.98105,"BASE":9.75552,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.77447,"PCHG2":22.23356,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-10 11:14:23","ADY":54,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-269","SUBJID":"id-269","SITEID":"USA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54767,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-17 11:14:23","TRTEDTM":"2022-05-17 05:14:23","TRT01SDTM":"2019-05-17 11:14:23","TRT01EDTM":"2021-05-16 23:14:23","TRT02SDTM":"2021-05-16 23:14:23","TRT02EDTM":"2022-05-17 05:14:23","AP01SDTM":"2019-05-17 11:14:23","AP01EDTM":"2021-05-16 23:14:23","AP02SDTM":"2021-05-16 23:14:23","AP02EDTM":"2022-05-17 05:14:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-17","EOSDY":1096,"LSTALVDT":"2022-06-09","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3535,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.00289,"AVALU":"mg/L","BASE2":7.98105,"BASE":9.75552,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.02184,"PCHG2":12.80333,"CHG":-0.75263,"PCHG":-7.71493,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-26 11:14:23","ADY":436,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-269","SUBJID":"id-269","SITEID":"USA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54767,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-17 11:14:23","TRTEDTM":"2022-05-17 05:14:23","TRT01SDTM":"2019-05-17 11:14:23","TRT01EDTM":"2021-05-16 23:14:23","TRT02SDTM":"2021-05-16 23:14:23","TRT02EDTM":"2022-05-17 05:14:23","AP01SDTM":"2019-05-17 11:14:23","AP01EDTM":"2021-05-16 23:14:23","AP02SDTM":"2021-05-16 23:14:23","AP02EDTM":"2022-05-17 05:14:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-17","EOSDY":1096,"LSTALVDT":"2022-06-09","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6857,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.01024,"AVALU":"mg/L","BASE2":7.98105,"BASE":9.75552,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.02919,"PCHG2":12.89539,"CHG":-0.74528,"PCHG":-7.63961,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-28 11:14:23","ADY":530,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-269","SUBJID":"id-269","SITEID":"USA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54767,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-17 11:14:23","TRTEDTM":"2022-05-17 05:14:23","TRT01SDTM":"2019-05-17 11:14:23","TRT01EDTM":"2021-05-16 23:14:23","TRT02SDTM":"2021-05-16 23:14:23","TRT02EDTM":"2022-05-17 05:14:23","AP01SDTM":"2019-05-17 11:14:23","AP01EDTM":"2021-05-16 23:14:23","AP02SDTM":"2021-05-16 23:14:23","AP02EDTM":"2022-05-17 05:14:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-17","EOSDY":1096,"LSTALVDT":"2022-06-09","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3492,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.48666,"AVALU":"mg/L","BASE2":7.98105,"BASE":9.75552,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.50561,"PCHG2":31.39448,"CHG":0.73114,"PCHG":7.49461,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-07-19 11:14:23","ADY":794,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-269","SUBJID":"id-269","SITEID":"USA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54767,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-17 11:14:23","TRTEDTM":"2022-05-17 05:14:23","TRT01SDTM":"2019-05-17 11:14:23","TRT01EDTM":"2021-05-16 23:14:23","TRT02SDTM":"2021-05-16 23:14:23","TRT02EDTM":"2022-05-17 05:14:23","AP01SDTM":"2019-05-17 11:14:23","AP01EDTM":"2021-05-16 23:14:23","AP02SDTM":"2021-05-16 23:14:23","AP02EDTM":"2022-05-17 05:14:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-17","EOSDY":1096,"LSTALVDT":"2022-06-09","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6177,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.02626,"AVALU":"mg/L","BASE2":7.98105,"BASE":9.75552,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.04521,"PCHG2":13.09618,"CHG":-0.72926,"PCHG":-7.47535,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-22 11:14:23","ADY":828,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-269","SUBJID":"id-269","SITEID":"USA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54767,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-17 11:14:23","TRTEDTM":"2022-05-17 05:14:23","TRT01SDTM":"2019-05-17 11:14:23","TRT01EDTM":"2021-05-16 23:14:23","TRT02SDTM":"2021-05-16 23:14:23","TRT02EDTM":"2022-05-17 05:14:23","AP01SDTM":"2019-05-17 11:14:23","AP01EDTM":"2021-05-16 23:14:23","AP02SDTM":"2021-05-16 23:14:23","AP02EDTM":"2022-05-17 05:14:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-17","EOSDY":1096,"LSTALVDT":"2022-06-09","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7560,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.93785,"AVALU":"mg/L","BASE2":7.98105,"BASE":9.75552,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.9568,"PCHG2":11.98841,"CHG":-0.81767,"PCHG":-8.38162,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-02 11:14:23","ADY":992,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-269","SUBJID":"id-269","SITEID":"USA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54767,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-17 11:14:23","TRTEDTM":"2022-05-17 05:14:23","TRT01SDTM":"2019-05-17 11:14:23","TRT01EDTM":"2021-05-16 23:14:23","TRT02SDTM":"2021-05-16 23:14:23","TRT02EDTM":"2022-05-17 05:14:23","AP01SDTM":"2019-05-17 11:14:23","AP01EDTM":"2021-05-16 23:14:23","AP02SDTM":"2021-05-16 23:14:23","AP02EDTM":"2022-05-17 05:14:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-17","EOSDY":1096,"LSTALVDT":"2022-06-09","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5615,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94218,"AVALU":"g/L","BASE2":2.94218,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-09 11:14:23","ADY":53,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-269","SUBJID":"id-269","SITEID":"USA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54767,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-17 11:14:23","TRTEDTM":"2022-05-17 05:14:23","TRT01SDTM":"2019-05-17 11:14:23","TRT01EDTM":"2021-05-16 23:14:23","TRT02SDTM":"2021-05-16 23:14:23","TRT02EDTM":"2022-05-17 05:14:23","AP01SDTM":"2019-05-17 11:14:23","AP01EDTM":"2021-05-16 23:14:23","AP02SDTM":"2021-05-16 23:14:23","AP02EDTM":"2022-05-17 05:14:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-17","EOSDY":1096,"LSTALVDT":"2022-06-09","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":835,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86231,"AVALU":"g/L","BASE2":2.94218,"BASE":2.86231,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.07987,"PCHG2":-2.71461,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-10 11:14:23","ADY":54,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-269","SUBJID":"id-269","SITEID":"USA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54767,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-17 11:14:23","TRTEDTM":"2022-05-17 05:14:23","TRT01SDTM":"2019-05-17 11:14:23","TRT01EDTM":"2021-05-16 23:14:23","TRT02SDTM":"2021-05-16 23:14:23","TRT02EDTM":"2022-05-17 05:14:23","AP01SDTM":"2019-05-17 11:14:23","AP01EDTM":"2021-05-16 23:14:23","AP02SDTM":"2021-05-16 23:14:23","AP02EDTM":"2022-05-17 05:14:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-17","EOSDY":1096,"LSTALVDT":"2022-06-09","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4552,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.10386,"AVALU":"g/L","BASE2":2.94218,"BASE":2.86231,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16168,"PCHG2":5.49509,"CHG":0.24154,"PCHG":8.43878,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-07-26 11:14:23","ADY":436,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-269","SUBJID":"id-269","SITEID":"USA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54767,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-17 11:14:23","TRTEDTM":"2022-05-17 05:14:23","TRT01SDTM":"2019-05-17 11:14:23","TRT01EDTM":"2021-05-16 23:14:23","TRT02SDTM":"2021-05-16 23:14:23","TRT02EDTM":"2022-05-17 05:14:23","AP01SDTM":"2019-05-17 11:14:23","AP01EDTM":"2021-05-16 23:14:23","AP02SDTM":"2021-05-16 23:14:23","AP02EDTM":"2022-05-17 05:14:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-17","EOSDY":1096,"LSTALVDT":"2022-06-09","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8219,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94622,"AVALU":"g/L","BASE2":2.94218,"BASE":2.86231,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00404,"PCHG2":0.1373,"CHG":0.08391,"PCHG":2.93149,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-28 11:14:23","ADY":530,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-269","SUBJID":"id-269","SITEID":"USA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54767,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-17 11:14:23","TRTEDTM":"2022-05-17 05:14:23","TRT01SDTM":"2019-05-17 11:14:23","TRT01EDTM":"2021-05-16 23:14:23","TRT02SDTM":"2021-05-16 23:14:23","TRT02EDTM":"2022-05-17 05:14:23","AP01SDTM":"2019-05-17 11:14:23","AP01EDTM":"2021-05-16 23:14:23","AP02SDTM":"2021-05-16 23:14:23","AP02EDTM":"2022-05-17 05:14:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-17","EOSDY":1096,"LSTALVDT":"2022-06-09","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4844,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93842,"AVALU":"g/L","BASE2":2.94218,"BASE":2.86231,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00376,"PCHG2":-0.12796,"CHG":0.0761,"PCHG":2.65883,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-19 11:14:23","ADY":794,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-269","SUBJID":"id-269","SITEID":"USA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54767,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-17 11:14:23","TRTEDTM":"2022-05-17 05:14:23","TRT01SDTM":"2019-05-17 11:14:23","TRT01EDTM":"2021-05-16 23:14:23","TRT02SDTM":"2021-05-16 23:14:23","TRT02EDTM":"2022-05-17 05:14:23","AP01SDTM":"2019-05-17 11:14:23","AP01EDTM":"2021-05-16 23:14:23","AP02SDTM":"2021-05-16 23:14:23","AP02EDTM":"2022-05-17 05:14:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-17","EOSDY":1096,"LSTALVDT":"2022-06-09","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6105,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.57833,"AVALU":"g/L","BASE2":2.94218,"BASE":2.86231,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.36385,"PCHG2":-12.36662,"CHG":-0.28398,"PCHG":-9.92134,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-22 11:14:23","ADY":828,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-269","SUBJID":"id-269","SITEID":"USA-1","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.54767,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-16","TRTSDTM":"2019-05-17 11:14:23","TRTEDTM":"2022-05-17 05:14:23","TRT01SDTM":"2019-05-17 11:14:23","TRT01EDTM":"2021-05-16 23:14:23","TRT02SDTM":"2021-05-16 23:14:23","TRT02EDTM":"2022-05-17 05:14:23","AP01SDTM":"2019-05-17 11:14:23","AP01EDTM":"2021-05-16 23:14:23","AP02SDTM":"2021-05-16 23:14:23","AP02EDTM":"2022-05-17 05:14:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-17","EOSDY":1096,"LSTALVDT":"2022-06-09","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5989,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88509,"AVALU":"g/L","BASE2":2.94218,"BASE":2.86231,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05709,"PCHG2":-1.94025,"CHG":0.02278,"PCHG":0.79596,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-02 11:14:23","ADY":992,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-295","SUBJID":"id-295","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.68619,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-09 23:49:26","TRTEDTM":"2022-08-09 17:49:26","TRT01SDTM":"2019-08-09 23:49:26","TRT01EDTM":"2021-08-09 11:49:26","TRT02SDTM":"2021-08-09 11:49:26","TRT02EDTM":"2022-08-09 17:49:26","AP01SDTM":"2019-08-09 23:49:26","AP01EDTM":"2021-08-09 11:49:26","AP02SDTM":"2021-08-09 11:49:26","AP02EDTM":"2022-08-09 17:49:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-09","EOSDY":1096,"LSTALVDT":"2022-08-28","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4842,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.64821,"AVALU":"U/L","BASE2":16.64821,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-10 23:49:26","ADY":185,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-295","SUBJID":"id-295","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.68619,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-09 23:49:26","TRTEDTM":"2022-08-09 17:49:26","TRT01SDTM":"2019-08-09 23:49:26","TRT01EDTM":"2021-08-09 11:49:26","TRT02SDTM":"2021-08-09 11:49:26","TRT02EDTM":"2022-08-09 17:49:26","AP01SDTM":"2019-08-09 23:49:26","AP01EDTM":"2021-08-09 11:49:26","AP02SDTM":"2021-08-09 11:49:26","AP02EDTM":"2022-08-09 17:49:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-09","EOSDY":1096,"LSTALVDT":"2022-08-28","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5456,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.4259,"AVALU":"U/L","BASE2":16.64821,"BASE":25.4259,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":8.77768,"PCHG2":52.72448,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-17 23:49:26","ADY":405,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-295","SUBJID":"id-295","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.68619,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-09 23:49:26","TRTEDTM":"2022-08-09 17:49:26","TRT01SDTM":"2019-08-09 23:49:26","TRT01EDTM":"2021-08-09 11:49:26","TRT02SDTM":"2021-08-09 11:49:26","TRT02EDTM":"2022-08-09 17:49:26","AP01SDTM":"2019-08-09 23:49:26","AP01EDTM":"2021-08-09 11:49:26","AP02SDTM":"2021-08-09 11:49:26","AP02EDTM":"2022-08-09 17:49:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-09","EOSDY":1096,"LSTALVDT":"2022-08-28","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4247,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.82919,"AVALU":"U/L","BASE2":16.64821,"BASE":25.4259,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.81903,"PCHG2":-22.93956,"CHG":-12.59671,"PCHG":-49.54284,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-29 23:49:26","ADY":690,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-295","SUBJID":"id-295","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.68619,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-09 23:49:26","TRTEDTM":"2022-08-09 17:49:26","TRT01SDTM":"2019-08-09 23:49:26","TRT01EDTM":"2021-08-09 11:49:26","TRT02SDTM":"2021-08-09 11:49:26","TRT02EDTM":"2022-08-09 17:49:26","AP01SDTM":"2019-08-09 23:49:26","AP01EDTM":"2021-08-09 11:49:26","AP02SDTM":"2021-08-09 11:49:26","AP02EDTM":"2022-08-09 17:49:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-09","EOSDY":1096,"LSTALVDT":"2022-08-28","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5169,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.86749,"AVALU":"U/L","BASE2":16.64821,"BASE":25.4259,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-4.78072,"PCHG2":-28.71614,"CHG":-13.55841,"PCHG":-53.32519,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-03 23:49:26","ADY":694,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-295","SUBJID":"id-295","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.68619,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-09 23:49:26","TRTEDTM":"2022-08-09 17:49:26","TRT01SDTM":"2019-08-09 23:49:26","TRT01EDTM":"2021-08-09 11:49:26","TRT02SDTM":"2021-08-09 11:49:26","TRT02EDTM":"2022-08-09 17:49:26","AP01SDTM":"2019-08-09 23:49:26","AP01EDTM":"2021-08-09 11:49:26","AP02SDTM":"2021-08-09 11:49:26","AP02EDTM":"2022-08-09 17:49:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-09","EOSDY":1096,"LSTALVDT":"2022-08-28","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4053,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.8757,"AVALU":"U/L","BASE2":16.64821,"BASE":25.4259,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.77252,"PCHG2":-4.64023,"CHG":-9.5502,"PCHG":-37.56092,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-17 23:49:26","ADY":923,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-295","SUBJID":"id-295","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.68619,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-09 23:49:26","TRTEDTM":"2022-08-09 17:49:26","TRT01SDTM":"2019-08-09 23:49:26","TRT01EDTM":"2021-08-09 11:49:26","TRT02SDTM":"2021-08-09 11:49:26","TRT02EDTM":"2022-08-09 17:49:26","AP01SDTM":"2019-08-09 23:49:26","AP01EDTM":"2021-08-09 11:49:26","AP02SDTM":"2021-08-09 11:49:26","AP02EDTM":"2022-08-09 17:49:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-09","EOSDY":1096,"LSTALVDT":"2022-08-28","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4353,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.59169,"AVALU":"U/L","BASE2":16.64821,"BASE":25.4259,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.94347,"PCHG2":5.6671,"CHG":-7.83421,"PCHG":-30.81194,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-02 23:49:26","ADY":1058,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-295","SUBJID":"id-295","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.68619,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-09 23:49:26","TRTEDTM":"2022-08-09 17:49:26","TRT01SDTM":"2019-08-09 23:49:26","TRT01EDTM":"2021-08-09 11:49:26","TRT02SDTM":"2021-08-09 11:49:26","TRT02EDTM":"2022-08-09 17:49:26","AP01SDTM":"2019-08-09 23:49:26","AP01EDTM":"2021-08-09 11:49:26","AP02SDTM":"2021-08-09 11:49:26","AP02EDTM":"2022-08-09 17:49:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-09","EOSDY":1096,"LSTALVDT":"2022-08-28","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6496,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.11076,"AVALU":"U/L","BASE2":16.64821,"BASE":25.4259,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.46254,"PCHG2":44.82488,"CHG":-1.31514,"PCHG":-5.17245,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-08 23:49:26","ADY":1095,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-295","SUBJID":"id-295","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.68619,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-09 23:49:26","TRTEDTM":"2022-08-09 17:49:26","TRT01SDTM":"2019-08-09 23:49:26","TRT01EDTM":"2021-08-09 11:49:26","TRT02SDTM":"2021-08-09 11:49:26","TRT02EDTM":"2022-08-09 17:49:26","AP01SDTM":"2019-08-09 23:49:26","AP01EDTM":"2021-08-09 11:49:26","AP02SDTM":"2021-08-09 11:49:26","AP02EDTM":"2022-08-09 17:49:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-09","EOSDY":1096,"LSTALVDT":"2022-08-28","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":793,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.65347,"AVALU":"mg/L","BASE2":10.65347,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-02-10 23:49:26","ADY":185,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-295","SUBJID":"id-295","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.68619,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-09 23:49:26","TRTEDTM":"2022-08-09 17:49:26","TRT01SDTM":"2019-08-09 23:49:26","TRT01EDTM":"2021-08-09 11:49:26","TRT02SDTM":"2021-08-09 11:49:26","TRT02EDTM":"2022-08-09 17:49:26","AP01SDTM":"2019-08-09 23:49:26","AP01EDTM":"2021-08-09 11:49:26","AP02SDTM":"2021-08-09 11:49:26","AP02EDTM":"2022-08-09 17:49:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-09","EOSDY":1096,"LSTALVDT":"2022-08-28","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3363,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.94415,"AVALU":"mg/L","BASE2":10.65347,"BASE":8.94415,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.70931,"PCHG2":-16.04466,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-17 23:49:26","ADY":405,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-295","SUBJID":"id-295","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.68619,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-09 23:49:26","TRTEDTM":"2022-08-09 17:49:26","TRT01SDTM":"2019-08-09 23:49:26","TRT01EDTM":"2021-08-09 11:49:26","TRT02SDTM":"2021-08-09 11:49:26","TRT02EDTM":"2022-08-09 17:49:26","AP01SDTM":"2019-08-09 23:49:26","AP01EDTM":"2021-08-09 11:49:26","AP02SDTM":"2021-08-09 11:49:26","AP02EDTM":"2022-08-09 17:49:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-09","EOSDY":1096,"LSTALVDT":"2022-08-28","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6726,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.50217,"AVALU":"mg/L","BASE2":10.65347,"BASE":8.94415,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.1513,"PCHG2":-10.80678,"CHG":0.55802,"PCHG":6.23889,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-29 23:49:26","ADY":690,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-295","SUBJID":"id-295","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.68619,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-09 23:49:26","TRTEDTM":"2022-08-09 17:49:26","TRT01SDTM":"2019-08-09 23:49:26","TRT01EDTM":"2021-08-09 11:49:26","TRT02SDTM":"2021-08-09 11:49:26","TRT02EDTM":"2022-08-09 17:49:26","AP01SDTM":"2019-08-09 23:49:26","AP01EDTM":"2021-08-09 11:49:26","AP02SDTM":"2021-08-09 11:49:26","AP02EDTM":"2022-08-09 17:49:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-09","EOSDY":1096,"LSTALVDT":"2022-08-28","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1285,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.57746,"AVALU":"mg/L","BASE2":10.65347,"BASE":8.94415,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07601,"PCHG2":-0.71346,"CHG":1.6333,"PCHG":18.26115,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-07-03 23:49:26","ADY":694,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-295","SUBJID":"id-295","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.68619,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-09 23:49:26","TRTEDTM":"2022-08-09 17:49:26","TRT01SDTM":"2019-08-09 23:49:26","TRT01EDTM":"2021-08-09 11:49:26","TRT02SDTM":"2021-08-09 11:49:26","TRT02EDTM":"2022-08-09 17:49:26","AP01SDTM":"2019-08-09 23:49:26","AP01EDTM":"2021-08-09 11:49:26","AP02SDTM":"2021-08-09 11:49:26","AP02EDTM":"2022-08-09 17:49:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-09","EOSDY":1096,"LSTALVDT":"2022-08-28","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5513,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.35175,"AVALU":"mg/L","BASE2":10.65347,"BASE":8.94415,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.30172,"PCHG2":-30.99194,"CHG":-1.5924,"PCHG":-17.80384,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-02-17 23:49:26","ADY":923,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-295","SUBJID":"id-295","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.68619,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-09 23:49:26","TRTEDTM":"2022-08-09 17:49:26","TRT01SDTM":"2019-08-09 23:49:26","TRT01EDTM":"2021-08-09 11:49:26","TRT02SDTM":"2021-08-09 11:49:26","TRT02EDTM":"2022-08-09 17:49:26","AP01SDTM":"2019-08-09 23:49:26","AP01EDTM":"2021-08-09 11:49:26","AP02SDTM":"2021-08-09 11:49:26","AP02EDTM":"2022-08-09 17:49:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-09","EOSDY":1096,"LSTALVDT":"2022-08-28","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1644,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.39896,"AVALU":"mg/L","BASE2":10.65347,"BASE":8.94415,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.2545,"PCHG2":-21.16214,"CHG":-0.54519,"PCHG":-6.09548,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-02 23:49:26","ADY":1058,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-295","SUBJID":"id-295","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.68619,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-09 23:49:26","TRTEDTM":"2022-08-09 17:49:26","TRT01SDTM":"2019-08-09 23:49:26","TRT01EDTM":"2021-08-09 11:49:26","TRT02SDTM":"2021-08-09 11:49:26","TRT02EDTM":"2022-08-09 17:49:26","AP01SDTM":"2019-08-09 23:49:26","AP01EDTM":"2021-08-09 11:49:26","AP02SDTM":"2021-08-09 11:49:26","AP02EDTM":"2022-08-09 17:49:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-09","EOSDY":1096,"LSTALVDT":"2022-08-28","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":259,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.91938,"AVALU":"mg/L","BASE2":10.65347,"BASE":8.94415,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.73408,"PCHG2":-25.66379,"CHG":-1.02477,"PCHG":-11.45743,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-08-08 23:49:26","ADY":1095,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-295","SUBJID":"id-295","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.68619,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-09 23:49:26","TRTEDTM":"2022-08-09 17:49:26","TRT01SDTM":"2019-08-09 23:49:26","TRT01EDTM":"2021-08-09 11:49:26","TRT02SDTM":"2021-08-09 11:49:26","TRT02EDTM":"2022-08-09 17:49:26","AP01SDTM":"2019-08-09 23:49:26","AP01EDTM":"2021-08-09 11:49:26","AP02SDTM":"2021-08-09 11:49:26","AP02EDTM":"2022-08-09 17:49:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-09","EOSDY":1096,"LSTALVDT":"2022-08-28","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8372,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85516,"AVALU":"g/L","BASE2":2.85516,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-02-10 23:49:26","ADY":185,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-295","SUBJID":"id-295","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.68619,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-09 23:49:26","TRTEDTM":"2022-08-09 17:49:26","TRT01SDTM":"2019-08-09 23:49:26","TRT01EDTM":"2021-08-09 11:49:26","TRT02SDTM":"2021-08-09 11:49:26","TRT02EDTM":"2022-08-09 17:49:26","AP01SDTM":"2019-08-09 23:49:26","AP01EDTM":"2021-08-09 11:49:26","AP02SDTM":"2021-08-09 11:49:26","AP02EDTM":"2022-08-09 17:49:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-09","EOSDY":1096,"LSTALVDT":"2022-08-28","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":454,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.09007,"AVALU":"g/L","BASE2":2.85516,"BASE":3.09007,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.23492,"PCHG2":8.22782,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2020-09-17 23:49:26","ADY":405,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-295","SUBJID":"id-295","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.68619,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-09 23:49:26","TRTEDTM":"2022-08-09 17:49:26","TRT01SDTM":"2019-08-09 23:49:26","TRT01EDTM":"2021-08-09 11:49:26","TRT02SDTM":"2021-08-09 11:49:26","TRT02EDTM":"2022-08-09 17:49:26","AP01SDTM":"2019-08-09 23:49:26","AP01EDTM":"2021-08-09 11:49:26","AP02SDTM":"2021-08-09 11:49:26","AP02EDTM":"2022-08-09 17:49:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-09","EOSDY":1096,"LSTALVDT":"2022-08-28","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5301,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87761,"AVALU":"g/L","BASE2":2.85516,"BASE":3.09007,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02246,"PCHG2":0.78656,"CHG":-0.21246,"PCHG":-6.87555,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-06-29 23:49:26","ADY":690,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-295","SUBJID":"id-295","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.68619,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-09 23:49:26","TRTEDTM":"2022-08-09 17:49:26","TRT01SDTM":"2019-08-09 23:49:26","TRT01EDTM":"2021-08-09 11:49:26","TRT02SDTM":"2021-08-09 11:49:26","TRT02EDTM":"2022-08-09 17:49:26","AP01SDTM":"2019-08-09 23:49:26","AP01EDTM":"2021-08-09 11:49:26","AP02SDTM":"2021-08-09 11:49:26","AP02EDTM":"2022-08-09 17:49:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-09","EOSDY":1096,"LSTALVDT":"2022-08-28","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1941,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76977,"AVALU":"g/L","BASE2":2.85516,"BASE":3.09007,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08539,"PCHG2":-2.9907,"CHG":-0.32031,"PCHG":-10.36565,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-07-03 23:49:26","ADY":694,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-295","SUBJID":"id-295","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.68619,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-09 23:49:26","TRTEDTM":"2022-08-09 17:49:26","TRT01SDTM":"2019-08-09 23:49:26","TRT01EDTM":"2021-08-09 11:49:26","TRT02SDTM":"2021-08-09 11:49:26","TRT02EDTM":"2022-08-09 17:49:26","AP01SDTM":"2019-08-09 23:49:26","AP01EDTM":"2021-08-09 11:49:26","AP02SDTM":"2021-08-09 11:49:26","AP02EDTM":"2022-08-09 17:49:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-09","EOSDY":1096,"LSTALVDT":"2022-08-28","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8299,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02088,"AVALU":"g/L","BASE2":2.85516,"BASE":3.09007,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16573,"PCHG2":5.80453,"CHG":-0.06919,"PCHG":-2.23906,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"3","BTOXGR":"3","ADTM":"2022-02-17 23:49:26","ADY":923,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-295","SUBJID":"id-295","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.68619,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-09 23:49:26","TRTEDTM":"2022-08-09 17:49:26","TRT01SDTM":"2019-08-09 23:49:26","TRT01EDTM":"2021-08-09 11:49:26","TRT02SDTM":"2021-08-09 11:49:26","TRT02EDTM":"2022-08-09 17:49:26","AP01SDTM":"2019-08-09 23:49:26","AP01EDTM":"2021-08-09 11:49:26","AP02SDTM":"2021-08-09 11:49:26","AP02EDTM":"2022-08-09 17:49:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-09","EOSDY":1096,"LSTALVDT":"2022-08-28","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1358,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96103,"AVALU":"g/L","BASE2":2.85516,"BASE":3.09007,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10588,"PCHG2":3.70826,"CHG":-0.12904,"PCHG":-4.17597,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-07-02 23:49:26","ADY":1058,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-295","SUBJID":"id-295","SITEID":"USA-1","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.68619,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-08-07","TRTSDTM":"2019-08-09 23:49:26","TRTEDTM":"2022-08-09 17:49:26","TRT01SDTM":"2019-08-09 23:49:26","TRT01EDTM":"2021-08-09 11:49:26","TRT02SDTM":"2021-08-09 11:49:26","TRT02EDTM":"2022-08-09 17:49:26","AP01SDTM":"2019-08-09 23:49:26","AP01EDTM":"2021-08-09 11:49:26","AP02SDTM":"2021-08-09 11:49:26","AP02EDTM":"2022-08-09 17:49:26","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-08-09","EOSDY":1096,"LSTALVDT":"2022-08-28","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6557,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95974,"AVALU":"g/L","BASE2":2.85516,"BASE":3.09007,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10458,"PCHG2":3.66288,"CHG":-0.13034,"PCHG":-4.2179,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2022-08-08 23:49:26","ADY":1095,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-394","SUBJID":"id-394","SITEID":"USA-1","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":6.14556,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-14","TRTSDTM":"2019-12-18 19:22:55","TRT01SDTM":"2019-12-18 19:22:55","AP01SDTM":"2019-12-18 19:22:55","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7311,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.24808,"AVALU":"U/L","BASE2":7.24808,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-16 19:22:55","ADY":60,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-394","SUBJID":"id-394","SITEID":"USA-1","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":6.14556,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-14","TRTSDTM":"2019-12-18 19:22:55","TRT01SDTM":"2019-12-18 19:22:55","AP01SDTM":"2019-12-18 19:22:55","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6950,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.59545,"AVALU":"U/L","BASE2":7.24808,"BASE":14.59545,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":7.34737,"PCHG2":101.36999,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-18 19:22:55","ADY":213,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-394","SUBJID":"id-394","SITEID":"USA-1","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":6.14556,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-14","TRTSDTM":"2019-12-18 19:22:55","TRT01SDTM":"2019-12-18 19:22:55","AP01SDTM":"2019-12-18 19:22:55","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2918,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.34812,"AVALU":"U/L","BASE2":7.24808,"BASE":14.59545,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.10004,"PCHG2":166.9414,"CHG":4.75267,"PCHG":32.56266,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-21 19:22:55","ADY":216,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-394","SUBJID":"id-394","SITEID":"USA-1","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":6.14556,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-14","TRTSDTM":"2019-12-18 19:22:55","TRT01SDTM":"2019-12-18 19:22:55","AP01SDTM":"2019-12-18 19:22:55","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2821,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.69343,"AVALU":"U/L","BASE2":7.24808,"BASE":14.59545,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.44535,"PCHG2":88.92498,"CHG":-0.90202,"PCHG":-6.18017,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-13 19:22:55","ADY":239,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-394","SUBJID":"id-394","SITEID":"USA-1","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":6.14556,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-14","TRTSDTM":"2019-12-18 19:22:55","TRT01SDTM":"2019-12-18 19:22:55","AP01SDTM":"2019-12-18 19:22:55","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6579,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.54277,"AVALU":"U/L","BASE2":7.24808,"BASE":14.59545,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.29469,"PCHG2":142.03343,"CHG":2.94732,"PCHG":20.1934,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-17 19:22:55","ADY":304,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-394","SUBJID":"id-394","SITEID":"USA-1","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":6.14556,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-14","TRTSDTM":"2019-12-18 19:22:55","TRT01SDTM":"2019-12-18 19:22:55","AP01SDTM":"2019-12-18 19:22:55","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8251,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.9322,"AVALU":"U/L","BASE2":7.24808,"BASE":14.59545,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.68412,"PCHG2":37.0322,"CHG":-4.66325,"PCHG":-31.95003,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-08 19:22:55","ADY":630,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-394","SUBJID":"id-394","SITEID":"USA-1","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":6.14556,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-14","TRTSDTM":"2019-12-18 19:22:55","TRT01SDTM":"2019-12-18 19:22:55","AP01SDTM":"2019-12-18 19:22:55","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3294,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":40.63941,"AVALU":"U/L","BASE2":7.24808,"BASE":14.59545,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":33.39133,"PCHG2":460.69231,"CHG":26.04396,"PCHG":178.43887,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-28 19:22:55","ADY":680,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-394","SUBJID":"id-394","SITEID":"USA-1","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":6.14556,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-14","TRTSDTM":"2019-12-18 19:22:55","TRT01SDTM":"2019-12-18 19:22:55","AP01SDTM":"2019-12-18 19:22:55","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":588,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.29342,"AVALU":"mg/L","BASE2":9.29342,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-16 19:22:55","ADY":60,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-394","SUBJID":"id-394","SITEID":"USA-1","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":6.14556,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-14","TRTSDTM":"2019-12-18 19:22:55","TRT01SDTM":"2019-12-18 19:22:55","AP01SDTM":"2019-12-18 19:22:55","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3616,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.01388,"AVALU":"mg/L","BASE2":9.29342,"BASE":9.01388,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.27954,"PCHG2":-3.00793,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-18 19:22:55","ADY":213,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-394","SUBJID":"id-394","SITEID":"USA-1","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":6.14556,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-14","TRTSDTM":"2019-12-18 19:22:55","TRT01SDTM":"2019-12-18 19:22:55","AP01SDTM":"2019-12-18 19:22:55","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4638,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.1473,"AVALU":"mg/L","BASE2":9.29342,"BASE":9.01388,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.85388,"PCHG2":9.18805,"CHG":1.13342,"PCHG":12.5742,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-07-21 19:22:55","ADY":216,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-394","SUBJID":"id-394","SITEID":"USA-1","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":6.14556,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-14","TRTSDTM":"2019-12-18 19:22:55","TRT01SDTM":"2019-12-18 19:22:55","AP01SDTM":"2019-12-18 19:22:55","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1897,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.84034,"AVALU":"mg/L","BASE2":9.29342,"BASE":9.01388,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.45307,"PCHG2":-4.87522,"CHG":-0.17354,"PCHG":-1.9252,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-13 19:22:55","ADY":239,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-394","SUBJID":"id-394","SITEID":"USA-1","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":6.14556,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-14","TRTSDTM":"2019-12-18 19:22:55","TRT01SDTM":"2019-12-18 19:22:55","AP01SDTM":"2019-12-18 19:22:55","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3296,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.35379,"AVALU":"mg/L","BASE2":9.29342,"BASE":9.01388,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.06037,"PCHG2":11.40994,"CHG":1.33991,"PCHG":14.865,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-10-17 19:22:55","ADY":304,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-394","SUBJID":"id-394","SITEID":"USA-1","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":6.14556,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-14","TRTSDTM":"2019-12-18 19:22:55","TRT01SDTM":"2019-12-18 19:22:55","AP01SDTM":"2019-12-18 19:22:55","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5874,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.2289,"AVALU":"mg/L","BASE2":9.29342,"BASE":9.01388,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.06452,"PCHG2":-11.45458,"CHG":-0.78498,"PCHG":-8.7086,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-08 19:22:55","ADY":630,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-394","SUBJID":"id-394","SITEID":"USA-1","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":6.14556,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-14","TRTSDTM":"2019-12-18 19:22:55","TRT01SDTM":"2019-12-18 19:22:55","AP01SDTM":"2019-12-18 19:22:55","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7028,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.81317,"AVALU":"mg/L","BASE2":9.29342,"BASE":9.01388,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.48025,"PCHG2":-5.1676,"CHG":-0.20071,"PCHG":-2.22664,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-28 19:22:55","ADY":680,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-394","SUBJID":"id-394","SITEID":"USA-1","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":6.14556,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-14","TRTSDTM":"2019-12-18 19:22:55","TRT01SDTM":"2019-12-18 19:22:55","AP01SDTM":"2019-12-18 19:22:55","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5852,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87983,"AVALU":"g/L","BASE2":2.87983,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-16 19:22:55","ADY":60,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-394","SUBJID":"id-394","SITEID":"USA-1","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":6.14556,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-14","TRTSDTM":"2019-12-18 19:22:55","TRT01SDTM":"2019-12-18 19:22:55","AP01SDTM":"2019-12-18 19:22:55","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2509,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.73931,"AVALU":"g/L","BASE2":2.87983,"BASE":2.73931,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.14052,"PCHG2":-4.87962,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-18 19:22:55","ADY":213,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-394","SUBJID":"id-394","SITEID":"USA-1","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":6.14556,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-14","TRTSDTM":"2019-12-18 19:22:55","TRT01SDTM":"2019-12-18 19:22:55","AP01SDTM":"2019-12-18 19:22:55","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1481,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05987,"AVALU":"g/L","BASE2":2.87983,"BASE":2.73931,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18003,"PCHG2":6.25157,"CHG":0.32056,"PCHG":11.70222,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-07-21 19:22:55","ADY":216,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-394","SUBJID":"id-394","SITEID":"USA-1","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":6.14556,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-14","TRTSDTM":"2019-12-18 19:22:55","TRT01SDTM":"2019-12-18 19:22:55","AP01SDTM":"2019-12-18 19:22:55","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3654,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98244,"AVALU":"g/L","BASE2":2.87983,"BASE":2.73931,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10261,"PCHG2":3.56298,"CHG":0.24313,"PCHG":8.8757,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-13 19:22:55","ADY":239,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-394","SUBJID":"id-394","SITEID":"USA-1","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":6.14556,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-14","TRTSDTM":"2019-12-18 19:22:55","TRT01SDTM":"2019-12-18 19:22:55","AP01SDTM":"2019-12-18 19:22:55","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1148,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95094,"AVALU":"g/L","BASE2":2.87983,"BASE":2.73931,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0711,"PCHG2":2.46898,"CHG":0.21163,"PCHG":7.72558,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-17 19:22:55","ADY":304,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-394","SUBJID":"id-394","SITEID":"USA-1","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":6.14556,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-14","TRTSDTM":"2019-12-18 19:22:55","TRT01SDTM":"2019-12-18 19:22:55","AP01SDTM":"2019-12-18 19:22:55","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2066,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88654,"AVALU":"g/L","BASE2":2.87983,"BASE":2.73931,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0067,"PCHG2":0.23273,"CHG":0.14723,"PCHG":5.37462,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-08 19:22:55","ADY":630,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-394","SUBJID":"id-394","SITEID":"USA-1","AGE":46,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":6.14556,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-14","TRTSDTM":"2019-12-18 19:22:55","TRT01SDTM":"2019-12-18 19:22:55","AP01SDTM":"2019-12-18 19:22:55","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1297,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.868,"AVALU":"g/L","BASE2":2.87983,"BASE":2.73931,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01183,"PCHG2":-0.41092,"CHG":0.12869,"PCHG":4.69794,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-28 19:22:55","ADY":680,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-45","SUBJID":"id-45","SITEID":"USA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":0.46356,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-04","TRTSDTM":"2019-03-06 06:32:29","TRTEDTM":"2022-03-06 00:32:29","TRT01SDTM":"2019-03-06 06:32:29","TRT01EDTM":"2021-03-05 18:32:29","TRT02SDTM":"2021-03-05 18:32:29","TRT02EDTM":"2022-03-06 00:32:29","AP01SDTM":"2019-03-06 06:32:29","AP01EDTM":"2021-03-05 18:32:29","AP02SDTM":"2021-03-05 18:32:29","AP02EDTM":"2022-03-06 00:32:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3098,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.87429,"AVALU":"U/L","BASE2":22.87429,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-15 06:32:29","ADY":131,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-45","SUBJID":"id-45","SITEID":"USA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":0.46356,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-04","TRTSDTM":"2019-03-06 06:32:29","TRTEDTM":"2022-03-06 00:32:29","TRT01SDTM":"2019-03-06 06:32:29","TRT01EDTM":"2021-03-05 18:32:29","TRT02SDTM":"2021-03-05 18:32:29","TRT02EDTM":"2022-03-06 00:32:29","AP01SDTM":"2019-03-06 06:32:29","AP01EDTM":"2021-03-05 18:32:29","AP02SDTM":"2021-03-05 18:32:29","AP02EDTM":"2022-03-06 00:32:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7700,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.04012,"AVALU":"U/L","BASE2":22.87429,"BASE":16.04012,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-6.83417,"PCHG2":-29.87709,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-25 06:32:29","ADY":203,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-45","SUBJID":"id-45","SITEID":"USA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":0.46356,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-04","TRTSDTM":"2019-03-06 06:32:29","TRTEDTM":"2022-03-06 00:32:29","TRT01SDTM":"2019-03-06 06:32:29","TRT01EDTM":"2021-03-05 18:32:29","TRT02SDTM":"2021-03-05 18:32:29","TRT02EDTM":"2022-03-06 00:32:29","AP01SDTM":"2019-03-06 06:32:29","AP01EDTM":"2021-03-05 18:32:29","AP02SDTM":"2021-03-05 18:32:29","AP02EDTM":"2022-03-06 00:32:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3309,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":36.29672,"AVALU":"U/L","BASE2":22.87429,"BASE":16.04012,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.42243,"PCHG2":58.6791,"CHG":20.2566,"PCHG":126.2871,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-10 06:32:29","ADY":462,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-45","SUBJID":"id-45","SITEID":"USA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":0.46356,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-04","TRTSDTM":"2019-03-06 06:32:29","TRTEDTM":"2022-03-06 00:32:29","TRT01SDTM":"2019-03-06 06:32:29","TRT01EDTM":"2021-03-05 18:32:29","TRT02SDTM":"2021-03-05 18:32:29","TRT02EDTM":"2022-03-06 00:32:29","AP01SDTM":"2019-03-06 06:32:29","AP01EDTM":"2021-03-05 18:32:29","AP02SDTM":"2021-03-05 18:32:29","AP02EDTM":"2022-03-06 00:32:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":642,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.02463,"AVALU":"U/L","BASE2":22.87429,"BASE":16.04012,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.84966,"PCHG2":-73.662,"CHG":-10.01549,"PCHG":-62.44024,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-06-17 06:32:29","ADY":469,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-45","SUBJID":"id-45","SITEID":"USA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":0.46356,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-04","TRTSDTM":"2019-03-06 06:32:29","TRTEDTM":"2022-03-06 00:32:29","TRT01SDTM":"2019-03-06 06:32:29","TRT01EDTM":"2021-03-05 18:32:29","TRT02SDTM":"2021-03-05 18:32:29","TRT02EDTM":"2022-03-06 00:32:29","AP01SDTM":"2019-03-06 06:32:29","AP01EDTM":"2021-03-05 18:32:29","AP02SDTM":"2021-03-05 18:32:29","AP02EDTM":"2022-03-06 00:32:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5732,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.55027,"AVALU":"U/L","BASE2":22.87429,"BASE":16.04012,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.67598,"PCHG2":11.69865,"CHG":9.51016,"PCHG":59.28981,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-27 06:32:29","ADY":540,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-45","SUBJID":"id-45","SITEID":"USA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":0.46356,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-04","TRTSDTM":"2019-03-06 06:32:29","TRTEDTM":"2022-03-06 00:32:29","TRT01SDTM":"2019-03-06 06:32:29","TRT01EDTM":"2021-03-05 18:32:29","TRT02SDTM":"2021-03-05 18:32:29","TRT02EDTM":"2022-03-06 00:32:29","AP01SDTM":"2019-03-06 06:32:29","AP01EDTM":"2021-03-05 18:32:29","AP02SDTM":"2021-03-05 18:32:29","AP02EDTM":"2022-03-06 00:32:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2372,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.40561,"AVALU":"U/L","BASE2":22.87429,"BASE":16.04012,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.46868,"PCHG2":-45.76616,"CHG":-3.63451,"PCHG":-22.65888,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-08 06:32:29","ADY":978,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-45","SUBJID":"id-45","SITEID":"USA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":0.46356,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-04","TRTSDTM":"2019-03-06 06:32:29","TRTEDTM":"2022-03-06 00:32:29","TRT01SDTM":"2019-03-06 06:32:29","TRT01EDTM":"2021-03-05 18:32:29","TRT02SDTM":"2021-03-05 18:32:29","TRT02EDTM":"2022-03-06 00:32:29","AP01SDTM":"2019-03-06 06:32:29","AP01EDTM":"2021-03-05 18:32:29","AP02SDTM":"2021-03-05 18:32:29","AP02EDTM":"2022-03-06 00:32:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3273,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.54576,"AVALU":"U/L","BASE2":22.87429,"BASE":16.04012,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.32853,"PCHG2":-27.66657,"CHG":0.50564,"PCHG":3.15235,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-25 06:32:29","ADY":1056,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-45","SUBJID":"id-45","SITEID":"USA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":0.46356,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-04","TRTSDTM":"2019-03-06 06:32:29","TRTEDTM":"2022-03-06 00:32:29","TRT01SDTM":"2019-03-06 06:32:29","TRT01EDTM":"2021-03-05 18:32:29","TRT02SDTM":"2021-03-05 18:32:29","TRT02EDTM":"2022-03-06 00:32:29","AP01SDTM":"2019-03-06 06:32:29","AP01EDTM":"2021-03-05 18:32:29","AP02SDTM":"2021-03-05 18:32:29","AP02EDTM":"2022-03-06 00:32:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5904,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.36947,"AVALU":"mg/L","BASE2":9.36947,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-15 06:32:29","ADY":131,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-45","SUBJID":"id-45","SITEID":"USA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":0.46356,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-04","TRTSDTM":"2019-03-06 06:32:29","TRTEDTM":"2022-03-06 00:32:29","TRT01SDTM":"2019-03-06 06:32:29","TRT01EDTM":"2021-03-05 18:32:29","TRT02SDTM":"2021-03-05 18:32:29","TRT02EDTM":"2022-03-06 00:32:29","AP01SDTM":"2019-03-06 06:32:29","AP01EDTM":"2021-03-05 18:32:29","AP02SDTM":"2021-03-05 18:32:29","AP02EDTM":"2022-03-06 00:32:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":998,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.69757,"AVALU":"mg/L","BASE2":9.36947,"BASE":8.69757,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.6719,"PCHG2":-7.17121,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-25 06:32:29","ADY":203,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-45","SUBJID":"id-45","SITEID":"USA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":0.46356,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-04","TRTSDTM":"2019-03-06 06:32:29","TRTEDTM":"2022-03-06 00:32:29","TRT01SDTM":"2019-03-06 06:32:29","TRT01EDTM":"2021-03-05 18:32:29","TRT02SDTM":"2021-03-05 18:32:29","TRT02EDTM":"2022-03-06 00:32:29","AP01SDTM":"2019-03-06 06:32:29","AP01EDTM":"2021-03-05 18:32:29","AP02SDTM":"2021-03-05 18:32:29","AP02EDTM":"2022-03-06 00:32:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4996,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.86501,"AVALU":"mg/L","BASE2":9.36947,"BASE":8.69757,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.50446,"PCHG2":-26.72999,"CHG":-1.83255,"PCHG":-21.06973,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2020-06-10 06:32:29","ADY":462,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-45","SUBJID":"id-45","SITEID":"USA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":0.46356,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-04","TRTSDTM":"2019-03-06 06:32:29","TRTEDTM":"2022-03-06 00:32:29","TRT01SDTM":"2019-03-06 06:32:29","TRT01EDTM":"2021-03-05 18:32:29","TRT02SDTM":"2021-03-05 18:32:29","TRT02EDTM":"2022-03-06 00:32:29","AP01SDTM":"2019-03-06 06:32:29","AP01EDTM":"2021-03-05 18:32:29","AP02SDTM":"2021-03-05 18:32:29","AP02EDTM":"2022-03-06 00:32:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2442,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.68988,"AVALU":"mg/L","BASE2":9.36947,"BASE":8.69757,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.67959,"PCHG2":-7.25327,"CHG":-0.00769,"PCHG":-0.0884,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-17 06:32:29","ADY":469,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-45","SUBJID":"id-45","SITEID":"USA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":0.46356,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-04","TRTSDTM":"2019-03-06 06:32:29","TRTEDTM":"2022-03-06 00:32:29","TRT01SDTM":"2019-03-06 06:32:29","TRT01EDTM":"2021-03-05 18:32:29","TRT02SDTM":"2021-03-05 18:32:29","TRT02EDTM":"2022-03-06 00:32:29","AP01SDTM":"2019-03-06 06:32:29","AP01EDTM":"2021-03-05 18:32:29","AP02SDTM":"2021-03-05 18:32:29","AP02EDTM":"2022-03-06 00:32:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6217,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.78802,"AVALU":"mg/L","BASE2":9.36947,"BASE":8.69757,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.58145,"PCHG2":-6.20583,"CHG":0.09045,"PCHG":1.03995,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-27 06:32:29","ADY":540,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-45","SUBJID":"id-45","SITEID":"USA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":0.46356,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-04","TRTSDTM":"2019-03-06 06:32:29","TRTEDTM":"2022-03-06 00:32:29","TRT01SDTM":"2019-03-06 06:32:29","TRT01EDTM":"2021-03-05 18:32:29","TRT02SDTM":"2021-03-05 18:32:29","TRT02EDTM":"2022-03-06 00:32:29","AP01SDTM":"2019-03-06 06:32:29","AP01EDTM":"2021-03-05 18:32:29","AP02SDTM":"2021-03-05 18:32:29","AP02EDTM":"2022-03-06 00:32:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":847,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.7313,"AVALU":"mg/L","BASE2":9.36947,"BASE":8.69757,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.63818,"PCHG2":-6.81122,"CHG":0.03373,"PCHG":0.3878,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-08 06:32:29","ADY":978,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-45","SUBJID":"id-45","SITEID":"USA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":0.46356,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-04","TRTSDTM":"2019-03-06 06:32:29","TRTEDTM":"2022-03-06 00:32:29","TRT01SDTM":"2019-03-06 06:32:29","TRT01EDTM":"2021-03-05 18:32:29","TRT02SDTM":"2021-03-05 18:32:29","TRT02EDTM":"2022-03-06 00:32:29","AP01SDTM":"2019-03-06 06:32:29","AP01EDTM":"2021-03-05 18:32:29","AP02SDTM":"2021-03-05 18:32:29","AP02EDTM":"2022-03-06 00:32:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4485,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.24511,"AVALU":"mg/L","BASE2":9.36947,"BASE":8.69757,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.12436,"PCHG2":-12.00029,"CHG":-0.45246,"PCHG":-5.20213,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-25 06:32:29","ADY":1056,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-45","SUBJID":"id-45","SITEID":"USA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":0.46356,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-04","TRTSDTM":"2019-03-06 06:32:29","TRTEDTM":"2022-03-06 00:32:29","TRT01SDTM":"2019-03-06 06:32:29","TRT01EDTM":"2021-03-05 18:32:29","TRT02SDTM":"2021-03-05 18:32:29","TRT02EDTM":"2022-03-06 00:32:29","AP01SDTM":"2019-03-06 06:32:29","AP01EDTM":"2021-03-05 18:32:29","AP02SDTM":"2021-03-05 18:32:29","AP02EDTM":"2022-03-06 00:32:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6227,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96751,"AVALU":"g/L","BASE2":2.96751,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-15 06:32:29","ADY":131,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-45","SUBJID":"id-45","SITEID":"USA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":0.46356,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-04","TRTSDTM":"2019-03-06 06:32:29","TRTEDTM":"2022-03-06 00:32:29","TRT01SDTM":"2019-03-06 06:32:29","TRT01EDTM":"2021-03-05 18:32:29","TRT02SDTM":"2021-03-05 18:32:29","TRT02EDTM":"2022-03-06 00:32:29","AP01SDTM":"2019-03-06 06:32:29","AP01EDTM":"2021-03-05 18:32:29","AP02SDTM":"2021-03-05 18:32:29","AP02EDTM":"2022-03-06 00:32:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4493,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9069,"AVALU":"g/L","BASE2":2.96751,"BASE":2.9069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.06061,"PCHG2":-2.04247,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-25 06:32:29","ADY":203,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-45","SUBJID":"id-45","SITEID":"USA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":0.46356,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-04","TRTSDTM":"2019-03-06 06:32:29","TRTEDTM":"2022-03-06 00:32:29","TRT01SDTM":"2019-03-06 06:32:29","TRT01EDTM":"2021-03-05 18:32:29","TRT02SDTM":"2021-03-05 18:32:29","TRT02EDTM":"2022-03-06 00:32:29","AP01SDTM":"2019-03-06 06:32:29","AP01EDTM":"2021-03-05 18:32:29","AP02SDTM":"2021-03-05 18:32:29","AP02EDTM":"2022-03-06 00:32:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1021,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75903,"AVALU":"g/L","BASE2":2.96751,"BASE":2.9069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20849,"PCHG2":-7.02562,"CHG":-0.14788,"PCHG":-5.08705,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-10 06:32:29","ADY":462,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-45","SUBJID":"id-45","SITEID":"USA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":0.46356,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-04","TRTSDTM":"2019-03-06 06:32:29","TRTEDTM":"2022-03-06 00:32:29","TRT01SDTM":"2019-03-06 06:32:29","TRT01EDTM":"2021-03-05 18:32:29","TRT02SDTM":"2021-03-05 18:32:29","TRT02EDTM":"2022-03-06 00:32:29","AP01SDTM":"2019-03-06 06:32:29","AP01EDTM":"2021-03-05 18:32:29","AP02SDTM":"2021-03-05 18:32:29","AP02EDTM":"2022-03-06 00:32:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5109,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93673,"AVALU":"g/L","BASE2":2.96751,"BASE":2.9069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03078,"PCHG2":-1.03729,"CHG":0.02983,"PCHG":1.02614,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-17 06:32:29","ADY":469,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-45","SUBJID":"id-45","SITEID":"USA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":0.46356,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-04","TRTSDTM":"2019-03-06 06:32:29","TRTEDTM":"2022-03-06 00:32:29","TRT01SDTM":"2019-03-06 06:32:29","TRT01EDTM":"2021-03-05 18:32:29","TRT02SDTM":"2021-03-05 18:32:29","TRT02EDTM":"2022-03-06 00:32:29","AP01SDTM":"2019-03-06 06:32:29","AP01EDTM":"2021-03-05 18:32:29","AP02SDTM":"2021-03-05 18:32:29","AP02EDTM":"2022-03-06 00:32:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1581,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86064,"AVALU":"g/L","BASE2":2.96751,"BASE":2.9069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10688,"PCHG2":-3.60158,"CHG":-0.04627,"PCHG":-1.59162,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-27 06:32:29","ADY":540,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-45","SUBJID":"id-45","SITEID":"USA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":0.46356,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-04","TRTSDTM":"2019-03-06 06:32:29","TRTEDTM":"2022-03-06 00:32:29","TRT01SDTM":"2019-03-06 06:32:29","TRT01EDTM":"2021-03-05 18:32:29","TRT02SDTM":"2021-03-05 18:32:29","TRT02EDTM":"2022-03-06 00:32:29","AP01SDTM":"2019-03-06 06:32:29","AP01EDTM":"2021-03-05 18:32:29","AP02SDTM":"2021-03-05 18:32:29","AP02EDTM":"2022-03-06 00:32:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7556,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97635,"AVALU":"g/L","BASE2":2.96751,"BASE":2.9069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00884,"PCHG2":0.29788,"CHG":0.06945,"PCHG":2.38914,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-08 06:32:29","ADY":978,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-1-id-45","SUBJID":"id-45","SITEID":"USA-1","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-1","INVNAM":"Dr. USA-1 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":0.46356,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-03-04","TRTSDTM":"2019-03-06 06:32:29","TRTEDTM":"2022-03-06 00:32:29","TRT01SDTM":"2019-03-06 06:32:29","TRT01EDTM":"2021-03-05 18:32:29","TRT02SDTM":"2021-03-05 18:32:29","TRT02EDTM":"2022-03-06 00:32:29","AP01SDTM":"2019-03-06 06:32:29","AP01EDTM":"2021-03-05 18:32:29","AP02SDTM":"2021-03-05 18:32:29","AP02EDTM":"2022-03-06 00:32:29","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-03-06","EOSDY":1096,"LSTALVDT":"2022-03-30","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6975,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93766,"AVALU":"g/L","BASE2":2.96751,"BASE":2.9069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02986,"PCHG2":-1.00609,"CHG":0.03075,"PCHG":1.05798,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-25 06:32:29","ADY":1056,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-100","SUBJID":"id-100","SITEID":"USA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":6.64371,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-08","TRTSDTM":"2020-03-10 18:02:56","TRTEDTM":"2022-02-13 11:12:36","TRT01SDTM":"2020-03-10 18:02:56","TRT01EDTM":"2021-02-13 05:12:36","TRT02SDTM":"2021-02-13 05:12:36","TRT02EDTM":"2022-02-13 11:12:36","AP01SDTM":"2020-03-10 18:02:56","AP01EDTM":"2021-02-13 05:12:36","AP02SDTM":"2021-02-13 05:12:36","AP02EDTM":"2022-02-13 11:12:36","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":705,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-10","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6459,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.4671,"AVALU":"U/L","BASE2":5.4671,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-1","BTOXGR":"0","ADTM":"2020-06-11 18:02:56","ADY":93,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-100","SUBJID":"id-100","SITEID":"USA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":6.64371,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-08","TRTSDTM":"2020-03-10 18:02:56","TRTEDTM":"2022-02-13 11:12:36","TRT01SDTM":"2020-03-10 18:02:56","TRT01EDTM":"2021-02-13 05:12:36","TRT02SDTM":"2021-02-13 05:12:36","TRT02EDTM":"2022-02-13 11:12:36","AP01SDTM":"2020-03-10 18:02:56","AP01EDTM":"2021-02-13 05:12:36","AP02SDTM":"2021-02-13 05:12:36","AP02EDTM":"2022-02-13 11:12:36","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":705,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-10","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1655,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.88775,"AVALU":"U/L","BASE2":5.4671,"BASE":28.88775,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":23.42064,"PCHG2":428.39226,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-10 18:02:56","ADY":153,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-100","SUBJID":"id-100","SITEID":"USA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":6.64371,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-08","TRTSDTM":"2020-03-10 18:02:56","TRTEDTM":"2022-02-13 11:12:36","TRT01SDTM":"2020-03-10 18:02:56","TRT01EDTM":"2021-02-13 05:12:36","TRT02SDTM":"2021-02-13 05:12:36","TRT02EDTM":"2022-02-13 11:12:36","AP01SDTM":"2020-03-10 18:02:56","AP01EDTM":"2021-02-13 05:12:36","AP02SDTM":"2021-02-13 05:12:36","AP02EDTM":"2022-02-13 11:12:36","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":705,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-10","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5912,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.07811,"AVALU":"U/L","BASE2":5.4671,"BASE":28.88775,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.61101,"PCHG2":11.17609,"CHG":-22.80964,"PCHG":-78.95955,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-02-01 18:02:56","ADY":328,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-100","SUBJID":"id-100","SITEID":"USA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":6.64371,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-08","TRTSDTM":"2020-03-10 18:02:56","TRTEDTM":"2022-02-13 11:12:36","TRT01SDTM":"2020-03-10 18:02:56","TRT01EDTM":"2021-02-13 05:12:36","TRT02SDTM":"2021-02-13 05:12:36","TRT02EDTM":"2022-02-13 11:12:36","AP01SDTM":"2020-03-10 18:02:56","AP01EDTM":"2021-02-13 05:12:36","AP02SDTM":"2021-02-13 05:12:36","AP02EDTM":"2022-02-13 11:12:36","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":705,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-10","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5657,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.31826,"AVALU":"U/L","BASE2":5.4671,"BASE":28.88775,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.85116,"PCHG2":161.89854,"CHG":-14.56948,"PCHG":-50.43483,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-16 18:02:56","ADY":402,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-100","SUBJID":"id-100","SITEID":"USA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":6.64371,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-08","TRTSDTM":"2020-03-10 18:02:56","TRTEDTM":"2022-02-13 11:12:36","TRT01SDTM":"2020-03-10 18:02:56","TRT01EDTM":"2021-02-13 05:12:36","TRT02SDTM":"2021-02-13 05:12:36","TRT02EDTM":"2022-02-13 11:12:36","AP01SDTM":"2020-03-10 18:02:56","AP01EDTM":"2021-02-13 05:12:36","AP02SDTM":"2021-02-13 05:12:36","AP02EDTM":"2022-02-13 11:12:36","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":705,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-10","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1860,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.77649,"AVALU":"U/L","BASE2":5.4671,"BASE":28.88775,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.30938,"PCHG2":133.69757,"CHG":-16.11126,"PCHG":-55.77196,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-16 18:02:56","ADY":463,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-100","SUBJID":"id-100","SITEID":"USA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":6.64371,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-08","TRTSDTM":"2020-03-10 18:02:56","TRTEDTM":"2022-02-13 11:12:36","TRT01SDTM":"2020-03-10 18:02:56","TRT01EDTM":"2021-02-13 05:12:36","TRT02SDTM":"2021-02-13 05:12:36","TRT02EDTM":"2022-02-13 11:12:36","AP01SDTM":"2020-03-10 18:02:56","AP01EDTM":"2021-02-13 05:12:36","AP02SDTM":"2021-02-13 05:12:36","AP02EDTM":"2022-02-13 11:12:36","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":705,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-10","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5148,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.95583,"AVALU":"U/L","BASE2":5.4671,"BASE":28.88775,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.48873,"PCHG2":118.68675,"CHG":-16.93192,"PCHG":-58.6128,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-02 18:02:56","ADY":694,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-100","SUBJID":"id-100","SITEID":"USA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":6.64371,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-08","TRTSDTM":"2020-03-10 18:02:56","TRTEDTM":"2022-02-13 11:12:36","TRT01SDTM":"2020-03-10 18:02:56","TRT01EDTM":"2021-02-13 05:12:36","TRT02SDTM":"2021-02-13 05:12:36","TRT02EDTM":"2022-02-13 11:12:36","AP01SDTM":"2020-03-10 18:02:56","AP01EDTM":"2021-02-13 05:12:36","AP02SDTM":"2021-02-13 05:12:36","AP02EDTM":"2022-02-13 11:12:36","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":705,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-10","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6500,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.99716,"AVALU":"U/L","BASE2":5.4671,"BASE":28.88775,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.53006,"PCHG2":192.6077,"CHG":-12.89058,"PCHG":-44.62302,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-12 18:02:56","ADY":704,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-100","SUBJID":"id-100","SITEID":"USA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":6.64371,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-08","TRTSDTM":"2020-03-10 18:02:56","TRTEDTM":"2022-02-13 11:12:36","TRT01SDTM":"2020-03-10 18:02:56","TRT01EDTM":"2021-02-13 05:12:36","TRT02SDTM":"2021-02-13 05:12:36","TRT02EDTM":"2022-02-13 11:12:36","AP01SDTM":"2020-03-10 18:02:56","AP01EDTM":"2021-02-13 05:12:36","AP02SDTM":"2021-02-13 05:12:36","AP02EDTM":"2022-02-13 11:12:36","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":705,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-10","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":632,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.3286,"AVALU":"mg/L","BASE2":10.3286,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"3","BTOXGR":"0","ADTM":"2020-06-11 18:02:56","ADY":93,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-100","SUBJID":"id-100","SITEID":"USA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":6.64371,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-08","TRTSDTM":"2020-03-10 18:02:56","TRTEDTM":"2022-02-13 11:12:36","TRT01SDTM":"2020-03-10 18:02:56","TRT01EDTM":"2021-02-13 05:12:36","TRT02SDTM":"2021-02-13 05:12:36","TRT02EDTM":"2022-02-13 11:12:36","AP01SDTM":"2020-03-10 18:02:56","AP01EDTM":"2021-02-13 05:12:36","AP02SDTM":"2021-02-13 05:12:36","AP02EDTM":"2022-02-13 11:12:36","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":705,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-10","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1829,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.83888,"AVALU":"mg/L","BASE2":10.3286,"BASE":8.83888,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.48972,"PCHG2":-14.42327,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-10 18:02:56","ADY":153,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-100","SUBJID":"id-100","SITEID":"USA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":6.64371,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-08","TRTSDTM":"2020-03-10 18:02:56","TRTEDTM":"2022-02-13 11:12:36","TRT01SDTM":"2020-03-10 18:02:56","TRT01EDTM":"2021-02-13 05:12:36","TRT02SDTM":"2021-02-13 05:12:36","TRT02EDTM":"2022-02-13 11:12:36","AP01SDTM":"2020-03-10 18:02:56","AP01EDTM":"2021-02-13 05:12:36","AP02SDTM":"2021-02-13 05:12:36","AP02EDTM":"2022-02-13 11:12:36","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":705,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-10","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3564,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.99231,"AVALU":"mg/L","BASE2":10.3286,"BASE":8.83888,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.33629,"PCHG2":-3.25595,"CHG":1.15343,"PCHG":13.04949,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-01 18:02:56","ADY":328,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-100","SUBJID":"id-100","SITEID":"USA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":6.64371,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-08","TRTSDTM":"2020-03-10 18:02:56","TRTEDTM":"2022-02-13 11:12:36","TRT01SDTM":"2020-03-10 18:02:56","TRT01EDTM":"2021-02-13 05:12:36","TRT02SDTM":"2021-02-13 05:12:36","TRT02EDTM":"2022-02-13 11:12:36","AP01SDTM":"2020-03-10 18:02:56","AP01EDTM":"2021-02-13 05:12:36","AP02SDTM":"2021-02-13 05:12:36","AP02EDTM":"2022-02-13 11:12:36","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":705,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-10","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8042,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.01915,"AVALU":"mg/L","BASE2":10.3286,"BASE":8.83888,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.30945,"PCHG2":-12.67795,"CHG":0.18027,"PCHG":2.03949,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-16 18:02:56","ADY":402,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-100","SUBJID":"id-100","SITEID":"USA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":6.64371,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-08","TRTSDTM":"2020-03-10 18:02:56","TRTEDTM":"2022-02-13 11:12:36","TRT01SDTM":"2020-03-10 18:02:56","TRT01EDTM":"2021-02-13 05:12:36","TRT02SDTM":"2021-02-13 05:12:36","TRT02EDTM":"2022-02-13 11:12:36","AP01SDTM":"2020-03-10 18:02:56","AP01EDTM":"2021-02-13 05:12:36","AP02SDTM":"2021-02-13 05:12:36","AP02EDTM":"2022-02-13 11:12:36","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":705,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-10","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6443,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.177,"AVALU":"mg/L","BASE2":10.3286,"BASE":8.83888,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.1516,"PCHG2":-11.14965,"CHG":0.33812,"PCHG":3.82537,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-16 18:02:56","ADY":463,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-100","SUBJID":"id-100","SITEID":"USA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":6.64371,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-08","TRTSDTM":"2020-03-10 18:02:56","TRTEDTM":"2022-02-13 11:12:36","TRT01SDTM":"2020-03-10 18:02:56","TRT01EDTM":"2021-02-13 05:12:36","TRT02SDTM":"2021-02-13 05:12:36","TRT02EDTM":"2022-02-13 11:12:36","AP01SDTM":"2020-03-10 18:02:56","AP01EDTM":"2021-02-13 05:12:36","AP02SDTM":"2021-02-13 05:12:36","AP02EDTM":"2022-02-13 11:12:36","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":705,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-10","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7436,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.94332,"AVALU":"mg/L","BASE2":10.3286,"BASE":8.83888,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.38528,"PCHG2":-13.41207,"CHG":0.10444,"PCHG":1.18163,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-02 18:02:56","ADY":694,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-100","SUBJID":"id-100","SITEID":"USA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":6.64371,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-08","TRTSDTM":"2020-03-10 18:02:56","TRTEDTM":"2022-02-13 11:12:36","TRT01SDTM":"2020-03-10 18:02:56","TRT01EDTM":"2021-02-13 05:12:36","TRT02SDTM":"2021-02-13 05:12:36","TRT02EDTM":"2022-02-13 11:12:36","AP01SDTM":"2020-03-10 18:02:56","AP01EDTM":"2021-02-13 05:12:36","AP02SDTM":"2021-02-13 05:12:36","AP02EDTM":"2022-02-13 11:12:36","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":705,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-10","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3663,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.26041,"AVALU":"mg/L","BASE2":10.3286,"BASE":8.83888,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.0682,"PCHG2":-20.02396,"CHG":-0.57847,"PCHG":-6.54464,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-12 18:02:56","ADY":704,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-100","SUBJID":"id-100","SITEID":"USA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":6.64371,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-08","TRTSDTM":"2020-03-10 18:02:56","TRTEDTM":"2022-02-13 11:12:36","TRT01SDTM":"2020-03-10 18:02:56","TRT01EDTM":"2021-02-13 05:12:36","TRT02SDTM":"2021-02-13 05:12:36","TRT02EDTM":"2022-02-13 11:12:36","AP01SDTM":"2020-03-10 18:02:56","AP01EDTM":"2021-02-13 05:12:36","AP02SDTM":"2021-02-13 05:12:36","AP02EDTM":"2022-02-13 11:12:36","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":705,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-10","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1950,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.14887,"AVALU":"g/L","BASE2":3.14887,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-06-11 18:02:56","ADY":93,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-100","SUBJID":"id-100","SITEID":"USA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":6.64371,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-08","TRTSDTM":"2020-03-10 18:02:56","TRTEDTM":"2022-02-13 11:12:36","TRT01SDTM":"2020-03-10 18:02:56","TRT01EDTM":"2021-02-13 05:12:36","TRT02SDTM":"2021-02-13 05:12:36","TRT02EDTM":"2022-02-13 11:12:36","AP01SDTM":"2020-03-10 18:02:56","AP01EDTM":"2021-02-13 05:12:36","AP02SDTM":"2021-02-13 05:12:36","AP02EDTM":"2022-02-13 11:12:36","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":705,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-10","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7201,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83535,"AVALU":"g/L","BASE2":3.14887,"BASE":2.83535,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.31352,"PCHG2":-9.95647,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-10 18:02:56","ADY":153,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-100","SUBJID":"id-100","SITEID":"USA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":6.64371,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-08","TRTSDTM":"2020-03-10 18:02:56","TRTEDTM":"2022-02-13 11:12:36","TRT01SDTM":"2020-03-10 18:02:56","TRT01EDTM":"2021-02-13 05:12:36","TRT02SDTM":"2021-02-13 05:12:36","TRT02EDTM":"2022-02-13 11:12:36","AP01SDTM":"2020-03-10 18:02:56","AP01EDTM":"2021-02-13 05:12:36","AP02SDTM":"2021-02-13 05:12:36","AP02EDTM":"2022-02-13 11:12:36","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":705,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-10","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3973,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92162,"AVALU":"g/L","BASE2":3.14887,"BASE":2.83535,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.22724,"PCHG2":-7.21663,"CHG":0.08627,"PCHG":3.0428,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-01 18:02:56","ADY":328,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-100","SUBJID":"id-100","SITEID":"USA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":6.64371,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-08","TRTSDTM":"2020-03-10 18:02:56","TRTEDTM":"2022-02-13 11:12:36","TRT01SDTM":"2020-03-10 18:02:56","TRT01EDTM":"2021-02-13 05:12:36","TRT02SDTM":"2021-02-13 05:12:36","TRT02EDTM":"2022-02-13 11:12:36","AP01SDTM":"2020-03-10 18:02:56","AP01EDTM":"2021-02-13 05:12:36","AP02SDTM":"2021-02-13 05:12:36","AP02EDTM":"2022-02-13 11:12:36","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":705,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-10","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8133,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96381,"AVALU":"g/L","BASE2":3.14887,"BASE":2.83535,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18505,"PCHG2":-5.87679,"CHG":0.12846,"PCHG":4.53079,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-16 18:02:56","ADY":402,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-100","SUBJID":"id-100","SITEID":"USA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":6.64371,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-08","TRTSDTM":"2020-03-10 18:02:56","TRTEDTM":"2022-02-13 11:12:36","TRT01SDTM":"2020-03-10 18:02:56","TRT01EDTM":"2021-02-13 05:12:36","TRT02SDTM":"2021-02-13 05:12:36","TRT02EDTM":"2022-02-13 11:12:36","AP01SDTM":"2020-03-10 18:02:56","AP01EDTM":"2021-02-13 05:12:36","AP02SDTM":"2021-02-13 05:12:36","AP02EDTM":"2022-02-13 11:12:36","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":705,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-10","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5032,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87103,"AVALU":"g/L","BASE2":3.14887,"BASE":2.83535,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.27783,"PCHG2":-8.82332,"CHG":0.03568,"PCHG":1.25845,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-16 18:02:56","ADY":463,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-100","SUBJID":"id-100","SITEID":"USA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":6.64371,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-08","TRTSDTM":"2020-03-10 18:02:56","TRTEDTM":"2022-02-13 11:12:36","TRT01SDTM":"2020-03-10 18:02:56","TRT01EDTM":"2021-02-13 05:12:36","TRT02SDTM":"2021-02-13 05:12:36","TRT02EDTM":"2022-02-13 11:12:36","AP01SDTM":"2020-03-10 18:02:56","AP01EDTM":"2021-02-13 05:12:36","AP02SDTM":"2021-02-13 05:12:36","AP02EDTM":"2022-02-13 11:12:36","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":705,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-10","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7516,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89404,"AVALU":"g/L","BASE2":3.14887,"BASE":2.83535,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.25482,"PCHG2":-8.0925,"CHG":0.05869,"PCHG":2.07008,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-02 18:02:56","ADY":694,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-100","SUBJID":"id-100","SITEID":"USA-11","AGE":40,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":6.64371,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-03-08","TRTSDTM":"2020-03-10 18:02:56","TRTEDTM":"2022-02-13 11:12:36","TRT01SDTM":"2020-03-10 18:02:56","TRT01EDTM":"2021-02-13 05:12:36","TRT02SDTM":"2021-02-13 05:12:36","TRT02EDTM":"2022-02-13 11:12:36","AP01SDTM":"2020-03-10 18:02:56","AP01EDTM":"2021-02-13 05:12:36","AP02SDTM":"2021-02-13 05:12:36","AP02EDTM":"2022-02-13 11:12:36","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-13","EOSDY":705,"DCSREAS":"LACK OF EFFICACY","LSTALVDT":"2022-03-10","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7417,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94362,"AVALU":"g/L","BASE2":3.14887,"BASE":2.83535,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20525,"PCHG2":-6.51807,"CHG":0.10827,"PCHG":3.8186,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-12 18:02:56","ADY":704,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-136","SUBJID":"id-136","SITEID":"USA-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.57955,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-09-28","TRTSDTM":"2019-10-02 05:04:53","TRTEDTM":"2022-02-12 11:48:41","TRT01SDTM":"2019-10-02 05:04:53","TRT01EDTM":"2021-02-12 05:48:41","TRT02SDTM":"2021-02-12 05:48:41","TRT02EDTM":"2022-02-12 11:48:41","AP01SDTM":"2019-10-02 05:04:53","AP01EDTM":"2021-02-12 05:48:41","AP02SDTM":"2021-02-12 05:48:41","AP02EDTM":"2022-02-12 11:48:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":865,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":913,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1558,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.38355,"AVALU":"U/L","BASE2":13.38355,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-27 05:04:53","ADY":86,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-136","SUBJID":"id-136","SITEID":"USA-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.57955,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-09-28","TRTSDTM":"2019-10-02 05:04:53","TRTEDTM":"2022-02-12 11:48:41","TRT01SDTM":"2019-10-02 05:04:53","TRT01EDTM":"2021-02-12 05:48:41","TRT02SDTM":"2021-02-12 05:48:41","TRT02EDTM":"2022-02-12 11:48:41","AP01SDTM":"2019-10-02 05:04:53","AP01EDTM":"2021-02-12 05:48:41","AP02SDTM":"2021-02-12 05:48:41","AP02EDTM":"2022-02-12 11:48:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":865,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":913,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":830,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.41846,"AVALU":"U/L","BASE2":13.38355,"BASE":31.41846,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":18.03491,"PCHG2":134.75427,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-29 05:04:53","ADY":150,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-136","SUBJID":"id-136","SITEID":"USA-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.57955,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-09-28","TRTSDTM":"2019-10-02 05:04:53","TRTEDTM":"2022-02-12 11:48:41","TRT01SDTM":"2019-10-02 05:04:53","TRT01EDTM":"2021-02-12 05:48:41","TRT02SDTM":"2021-02-12 05:48:41","TRT02EDTM":"2022-02-12 11:48:41","AP01SDTM":"2019-10-02 05:04:53","AP01EDTM":"2021-02-12 05:48:41","AP02SDTM":"2021-02-12 05:48:41","AP02EDTM":"2022-02-12 11:48:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":865,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":913,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3412,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.84616,"AVALU":"U/L","BASE2":13.38355,"BASE":31.41846,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.4626,"PCHG2":25.87209,"CHG":-14.5723,"PCHG":-46.38134,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-01 05:04:53","ADY":426,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-136","SUBJID":"id-136","SITEID":"USA-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.57955,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-09-28","TRTSDTM":"2019-10-02 05:04:53","TRTEDTM":"2022-02-12 11:48:41","TRT01SDTM":"2019-10-02 05:04:53","TRT01EDTM":"2021-02-12 05:48:41","TRT02SDTM":"2021-02-12 05:48:41","TRT02EDTM":"2022-02-12 11:48:41","AP01SDTM":"2019-10-02 05:04:53","AP01EDTM":"2021-02-12 05:48:41","AP02SDTM":"2021-02-12 05:48:41","AP02EDTM":"2022-02-12 11:48:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":865,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":913,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":772,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.07313,"AVALU":"U/L","BASE2":13.38355,"BASE":31.41846,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.68958,"PCHG2":27.568,"CHG":-14.34533,"PCHG":-45.65892,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-16 05:04:53","ADY":472,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-136","SUBJID":"id-136","SITEID":"USA-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.57955,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-09-28","TRTSDTM":"2019-10-02 05:04:53","TRTEDTM":"2022-02-12 11:48:41","TRT01SDTM":"2019-10-02 05:04:53","TRT01EDTM":"2021-02-12 05:48:41","TRT02SDTM":"2021-02-12 05:48:41","TRT02EDTM":"2022-02-12 11:48:41","AP01SDTM":"2019-10-02 05:04:53","AP01EDTM":"2021-02-12 05:48:41","AP02SDTM":"2021-02-12 05:48:41","AP02EDTM":"2022-02-12 11:48:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":865,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":913,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1465,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.22836,"AVALU":"U/L","BASE2":13.38355,"BASE":31.41846,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.15519,"PCHG2":-8.63142,"CHG":-19.1901,"PCHG":-61.07905,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-02 05:04:53","ADY":489,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-136","SUBJID":"id-136","SITEID":"USA-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.57955,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-09-28","TRTSDTM":"2019-10-02 05:04:53","TRTEDTM":"2022-02-12 11:48:41","TRT01SDTM":"2019-10-02 05:04:53","TRT01EDTM":"2021-02-12 05:48:41","TRT02SDTM":"2021-02-12 05:48:41","TRT02EDTM":"2022-02-12 11:48:41","AP01SDTM":"2019-10-02 05:04:53","AP01EDTM":"2021-02-12 05:48:41","AP02SDTM":"2021-02-12 05:48:41","AP02EDTM":"2022-02-12 11:48:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":865,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":913,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6162,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.78584,"AVALU":"U/L","BASE2":13.38355,"BASE":31.41846,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.59771,"PCHG2":-11.93787,"CHG":-19.63262,"PCHG":-62.48753,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-24 05:04:53","ADY":631,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-136","SUBJID":"id-136","SITEID":"USA-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.57955,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-09-28","TRTSDTM":"2019-10-02 05:04:53","TRTEDTM":"2022-02-12 11:48:41","TRT01SDTM":"2019-10-02 05:04:53","TRT01EDTM":"2021-02-12 05:48:41","TRT02SDTM":"2021-02-12 05:48:41","TRT02EDTM":"2022-02-12 11:48:41","AP01SDTM":"2019-10-02 05:04:53","AP01EDTM":"2021-02-12 05:48:41","AP02SDTM":"2021-02-12 05:48:41","AP02EDTM":"2022-02-12 11:48:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":865,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":913,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3076,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.13002,"AVALU":"U/L","BASE2":13.38355,"BASE":31.41846,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.74647,"PCHG2":42.93677,"CHG":-12.28844,"PCHG":-39.11217,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-01 05:04:53","ADY":638,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-136","SUBJID":"id-136","SITEID":"USA-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.57955,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-09-28","TRTSDTM":"2019-10-02 05:04:53","TRTEDTM":"2022-02-12 11:48:41","TRT01SDTM":"2019-10-02 05:04:53","TRT01EDTM":"2021-02-12 05:48:41","TRT02SDTM":"2021-02-12 05:48:41","TRT02EDTM":"2022-02-12 11:48:41","AP01SDTM":"2019-10-02 05:04:53","AP01EDTM":"2021-02-12 05:48:41","AP02SDTM":"2021-02-12 05:48:41","AP02EDTM":"2022-02-12 11:48:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":865,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":913,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1459,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.98646,"AVALU":"mg/L","BASE2":9.98646,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-27 05:04:53","ADY":86,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-136","SUBJID":"id-136","SITEID":"USA-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.57955,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-09-28","TRTSDTM":"2019-10-02 05:04:53","TRTEDTM":"2022-02-12 11:48:41","TRT01SDTM":"2019-10-02 05:04:53","TRT01EDTM":"2021-02-12 05:48:41","TRT02SDTM":"2021-02-12 05:48:41","TRT02EDTM":"2022-02-12 11:48:41","AP01SDTM":"2019-10-02 05:04:53","AP01EDTM":"2021-02-12 05:48:41","AP02SDTM":"2021-02-12 05:48:41","AP02EDTM":"2022-02-12 11:48:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":865,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":913,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":833,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.39608,"AVALU":"mg/L","BASE2":9.98646,"BASE":9.39608,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.59037,"PCHG2":-5.91173,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-29 05:04:53","ADY":150,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-136","SUBJID":"id-136","SITEID":"USA-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.57955,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-09-28","TRTSDTM":"2019-10-02 05:04:53","TRTEDTM":"2022-02-12 11:48:41","TRT01SDTM":"2019-10-02 05:04:53","TRT01EDTM":"2021-02-12 05:48:41","TRT02SDTM":"2021-02-12 05:48:41","TRT02EDTM":"2022-02-12 11:48:41","AP01SDTM":"2019-10-02 05:04:53","AP01EDTM":"2021-02-12 05:48:41","AP02SDTM":"2021-02-12 05:48:41","AP02EDTM":"2022-02-12 11:48:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":865,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":913,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8092,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.31535,"AVALU":"mg/L","BASE2":9.98646,"BASE":9.39608,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.67111,"PCHG2":-6.72017,"CHG":-0.08073,"PCHG":-0.85923,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-01 05:04:53","ADY":426,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-136","SUBJID":"id-136","SITEID":"USA-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.57955,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-09-28","TRTSDTM":"2019-10-02 05:04:53","TRTEDTM":"2022-02-12 11:48:41","TRT01SDTM":"2019-10-02 05:04:53","TRT01EDTM":"2021-02-12 05:48:41","TRT02SDTM":"2021-02-12 05:48:41","TRT02EDTM":"2022-02-12 11:48:41","AP01SDTM":"2019-10-02 05:04:53","AP01EDTM":"2021-02-12 05:48:41","AP02SDTM":"2021-02-12 05:48:41","AP02EDTM":"2022-02-12 11:48:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":865,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":913,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4045,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.029,"AVALU":"mg/L","BASE2":9.98646,"BASE":9.39608,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.95745,"PCHG2":-9.58753,"CHG":-0.36708,"PCHG":-3.90676,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-16 05:04:53","ADY":472,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-136","SUBJID":"id-136","SITEID":"USA-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.57955,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-09-28","TRTSDTM":"2019-10-02 05:04:53","TRTEDTM":"2022-02-12 11:48:41","TRT01SDTM":"2019-10-02 05:04:53","TRT01EDTM":"2021-02-12 05:48:41","TRT02SDTM":"2021-02-12 05:48:41","TRT02EDTM":"2022-02-12 11:48:41","AP01SDTM":"2019-10-02 05:04:53","AP01EDTM":"2021-02-12 05:48:41","AP02SDTM":"2021-02-12 05:48:41","AP02EDTM":"2022-02-12 11:48:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":865,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":913,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7065,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.90675,"AVALU":"mg/L","BASE2":9.98646,"BASE":9.39608,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0797,"PCHG2":-0.79811,"CHG":0.51067,"PCHG":5.43491,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-02 05:04:53","ADY":489,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-136","SUBJID":"id-136","SITEID":"USA-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.57955,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-09-28","TRTSDTM":"2019-10-02 05:04:53","TRTEDTM":"2022-02-12 11:48:41","TRT01SDTM":"2019-10-02 05:04:53","TRT01EDTM":"2021-02-12 05:48:41","TRT02SDTM":"2021-02-12 05:48:41","TRT02EDTM":"2022-02-12 11:48:41","AP01SDTM":"2019-10-02 05:04:53","AP01EDTM":"2021-02-12 05:48:41","AP02SDTM":"2021-02-12 05:48:41","AP02EDTM":"2022-02-12 11:48:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":865,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":913,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4324,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.06407,"AVALU":"mg/L","BASE2":9.98646,"BASE":9.39608,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.92239,"PCHG2":-19.24993,"CHG":-1.33201,"PCHG":-14.17626,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-24 05:04:53","ADY":631,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-136","SUBJID":"id-136","SITEID":"USA-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.57955,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-09-28","TRTSDTM":"2019-10-02 05:04:53","TRTEDTM":"2022-02-12 11:48:41","TRT01SDTM":"2019-10-02 05:04:53","TRT01EDTM":"2021-02-12 05:48:41","TRT02SDTM":"2021-02-12 05:48:41","TRT02EDTM":"2022-02-12 11:48:41","AP01SDTM":"2019-10-02 05:04:53","AP01EDTM":"2021-02-12 05:48:41","AP02SDTM":"2021-02-12 05:48:41","AP02EDTM":"2022-02-12 11:48:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":865,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":913,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":73,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.47432,"AVALU":"mg/L","BASE2":9.98646,"BASE":9.39608,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.51214,"PCHG2":-5.12831,"CHG":0.07824,"PCHG":0.83264,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-01 05:04:53","ADY":638,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-136","SUBJID":"id-136","SITEID":"USA-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.57955,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-09-28","TRTSDTM":"2019-10-02 05:04:53","TRTEDTM":"2022-02-12 11:48:41","TRT01SDTM":"2019-10-02 05:04:53","TRT01EDTM":"2021-02-12 05:48:41","TRT02SDTM":"2021-02-12 05:48:41","TRT02EDTM":"2022-02-12 11:48:41","AP01SDTM":"2019-10-02 05:04:53","AP01EDTM":"2021-02-12 05:48:41","AP02SDTM":"2021-02-12 05:48:41","AP02EDTM":"2022-02-12 11:48:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":865,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":913,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3751,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89317,"AVALU":"g/L","BASE2":2.89317,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-27 05:04:53","ADY":86,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-136","SUBJID":"id-136","SITEID":"USA-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.57955,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-09-28","TRTSDTM":"2019-10-02 05:04:53","TRTEDTM":"2022-02-12 11:48:41","TRT01SDTM":"2019-10-02 05:04:53","TRT01EDTM":"2021-02-12 05:48:41","TRT02SDTM":"2021-02-12 05:48:41","TRT02EDTM":"2022-02-12 11:48:41","AP01SDTM":"2019-10-02 05:04:53","AP01EDTM":"2021-02-12 05:48:41","AP02SDTM":"2021-02-12 05:48:41","AP02EDTM":"2022-02-12 11:48:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":865,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":913,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4112,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89399,"AVALU":"g/L","BASE2":2.89317,"BASE":2.89399,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.00082,"PCHG2":0.02851,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-29 05:04:53","ADY":150,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-136","SUBJID":"id-136","SITEID":"USA-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.57955,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-09-28","TRTSDTM":"2019-10-02 05:04:53","TRTEDTM":"2022-02-12 11:48:41","TRT01SDTM":"2019-10-02 05:04:53","TRT01EDTM":"2021-02-12 05:48:41","TRT02SDTM":"2021-02-12 05:48:41","TRT02EDTM":"2022-02-12 11:48:41","AP01SDTM":"2019-10-02 05:04:53","AP01EDTM":"2021-02-12 05:48:41","AP02SDTM":"2021-02-12 05:48:41","AP02EDTM":"2022-02-12 11:48:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":865,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":913,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1499,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88875,"AVALU":"g/L","BASE2":2.89317,"BASE":2.89399,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00441,"PCHG2":-0.15249,"CHG":-0.00524,"PCHG":-0.18094,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-01 05:04:53","ADY":426,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-136","SUBJID":"id-136","SITEID":"USA-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.57955,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-09-28","TRTSDTM":"2019-10-02 05:04:53","TRTEDTM":"2022-02-12 11:48:41","TRT01SDTM":"2019-10-02 05:04:53","TRT01EDTM":"2021-02-12 05:48:41","TRT02SDTM":"2021-02-12 05:48:41","TRT02EDTM":"2022-02-12 11:48:41","AP01SDTM":"2019-10-02 05:04:53","AP01EDTM":"2021-02-12 05:48:41","AP02SDTM":"2021-02-12 05:48:41","AP02EDTM":"2022-02-12 11:48:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":865,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":913,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3348,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78837,"AVALU":"g/L","BASE2":2.89317,"BASE":2.89399,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1048,"PCHG2":-3.62221,"CHG":-0.10562,"PCHG":-3.64968,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-16 05:04:53","ADY":472,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-136","SUBJID":"id-136","SITEID":"USA-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.57955,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-09-28","TRTSDTM":"2019-10-02 05:04:53","TRTEDTM":"2022-02-12 11:48:41","TRT01SDTM":"2019-10-02 05:04:53","TRT01EDTM":"2021-02-12 05:48:41","TRT02SDTM":"2021-02-12 05:48:41","TRT02EDTM":"2022-02-12 11:48:41","AP01SDTM":"2019-10-02 05:04:53","AP01EDTM":"2021-02-12 05:48:41","AP02SDTM":"2021-02-12 05:48:41","AP02EDTM":"2022-02-12 11:48:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":865,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":913,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4136,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.02394,"AVALU":"g/L","BASE2":2.89317,"BASE":2.89399,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13078,"PCHG2":4.52016,"CHG":0.12995,"PCHG":4.49038,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-02-02 05:04:53","ADY":489,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-136","SUBJID":"id-136","SITEID":"USA-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.57955,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-09-28","TRTSDTM":"2019-10-02 05:04:53","TRTEDTM":"2022-02-12 11:48:41","TRT01SDTM":"2019-10-02 05:04:53","TRT01EDTM":"2021-02-12 05:48:41","TRT02SDTM":"2021-02-12 05:48:41","TRT02EDTM":"2022-02-12 11:48:41","AP01SDTM":"2019-10-02 05:04:53","AP01EDTM":"2021-02-12 05:48:41","AP02SDTM":"2021-02-12 05:48:41","AP02EDTM":"2022-02-12 11:48:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":865,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":913,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7239,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88842,"AVALU":"g/L","BASE2":2.89317,"BASE":2.89399,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00474,"PCHG2":-0.16399,"CHG":-0.00557,"PCHG":-0.19245,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-24 05:04:53","ADY":631,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-136","SUBJID":"id-136","SITEID":"USA-11","AGE":38,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.57955,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2019-09-28","TRTSDTM":"2019-10-02 05:04:53","TRTEDTM":"2022-02-12 11:48:41","TRT01SDTM":"2019-10-02 05:04:53","TRT01EDTM":"2021-02-12 05:48:41","TRT02SDTM":"2021-02-12 05:48:41","TRT02EDTM":"2022-02-12 11:48:41","AP01SDTM":"2019-10-02 05:04:53","AP01EDTM":"2021-02-12 05:48:41","AP02SDTM":"2021-02-12 05:48:41","AP02EDTM":"2022-02-12 11:48:41","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-12","EOSDY":865,"DCSREAS":"DEATH","DTHDT":"2022-04-03","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":50,"LDDTHGR1":">30","LSTALVDT":"2022-04-03","DTHADY":913,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2280,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88873,"AVALU":"g/L","BASE2":2.89317,"BASE":2.89399,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00444,"PCHG2":-0.1534,"CHG":-0.00526,"PCHG":-0.18186,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-01 05:04:53","ADY":638,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-157","SUBJID":"id-157","SITEID":"USA-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":6.18035,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-06-14","TRTSDTM":"2020-06-14 21:16:44","TRTEDTM":"2023-06-15 15:16:44","TRT01SDTM":"2020-06-14 21:16:44","TRT01EDTM":"2022-06-15 09:16:44","TRT02SDTM":"2022-06-15 09:16:44","TRT02EDTM":"2023-06-15 15:16:44","AP01SDTM":"2020-06-14 21:16:44","AP01EDTM":"2022-06-15 09:16:44","AP02SDTM":"2022-06-15 09:16:44","AP02EDTM":"2023-06-15 15:16:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-15","EOSDY":1096,"LSTALVDT":"2023-07-14","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5601,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.10887,"AVALU":"U/L","BASE2":6.10887,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-02-16 21:16:44","ADY":247,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-157","SUBJID":"id-157","SITEID":"USA-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":6.18035,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-06-14","TRTSDTM":"2020-06-14 21:16:44","TRTEDTM":"2023-06-15 15:16:44","TRT01SDTM":"2020-06-14 21:16:44","TRT01EDTM":"2022-06-15 09:16:44","TRT02SDTM":"2022-06-15 09:16:44","TRT02EDTM":"2023-06-15 15:16:44","AP01SDTM":"2020-06-14 21:16:44","AP01EDTM":"2022-06-15 09:16:44","AP02SDTM":"2022-06-15 09:16:44","AP02EDTM":"2023-06-15 15:16:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-15","EOSDY":1096,"LSTALVDT":"2023-07-14","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6316,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.50713,"AVALU":"U/L","BASE2":6.10887,"BASE":27.50713,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":21.39826,"PCHG2":350.28197,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-29 21:16:44","ADY":319,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-157","SUBJID":"id-157","SITEID":"USA-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":6.18035,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-06-14","TRTSDTM":"2020-06-14 21:16:44","TRTEDTM":"2023-06-15 15:16:44","TRT01SDTM":"2020-06-14 21:16:44","TRT01EDTM":"2022-06-15 09:16:44","TRT02SDTM":"2022-06-15 09:16:44","TRT02EDTM":"2023-06-15 15:16:44","AP01SDTM":"2020-06-14 21:16:44","AP01EDTM":"2022-06-15 09:16:44","AP02SDTM":"2022-06-15 09:16:44","AP02EDTM":"2023-06-15 15:16:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-15","EOSDY":1096,"LSTALVDT":"2023-07-14","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3354,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.85895,"AVALU":"U/L","BASE2":6.10887,"BASE":27.50713,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.75009,"PCHG2":175.97513,"CHG":-10.64817,"PCHG":-38.7106,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-07 21:16:44","ADY":327,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-157","SUBJID":"id-157","SITEID":"USA-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":6.18035,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-06-14","TRTSDTM":"2020-06-14 21:16:44","TRTEDTM":"2023-06-15 15:16:44","TRT01SDTM":"2020-06-14 21:16:44","TRT01EDTM":"2022-06-15 09:16:44","TRT02SDTM":"2022-06-15 09:16:44","TRT02EDTM":"2023-06-15 15:16:44","AP01SDTM":"2020-06-14 21:16:44","AP01EDTM":"2022-06-15 09:16:44","AP02SDTM":"2022-06-15 09:16:44","AP02EDTM":"2023-06-15 15:16:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-15","EOSDY":1096,"LSTALVDT":"2023-07-14","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3333,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":36.62195,"AVALU":"U/L","BASE2":6.10887,"BASE":27.50713,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":30.51308,"PCHG2":499.48842,"CHG":9.11482,"PCHG":33.13623,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-02 21:16:44","ADY":353,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-157","SUBJID":"id-157","SITEID":"USA-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":6.18035,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-06-14","TRTSDTM":"2020-06-14 21:16:44","TRTEDTM":"2023-06-15 15:16:44","TRT01SDTM":"2020-06-14 21:16:44","TRT01EDTM":"2022-06-15 09:16:44","TRT02SDTM":"2022-06-15 09:16:44","TRT02EDTM":"2023-06-15 15:16:44","AP01SDTM":"2020-06-14 21:16:44","AP01EDTM":"2022-06-15 09:16:44","AP02SDTM":"2022-06-15 09:16:44","AP02EDTM":"2023-06-15 15:16:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-15","EOSDY":1096,"LSTALVDT":"2023-07-14","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4535,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.54804,"AVALU":"U/L","BASE2":6.10887,"BASE":27.50713,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":24.43917,"PCHG2":400.06063,"CHG":3.04091,"PCHG":11.055,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-12 21:16:44","ADY":577,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-157","SUBJID":"id-157","SITEID":"USA-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":6.18035,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-06-14","TRTSDTM":"2020-06-14 21:16:44","TRTEDTM":"2023-06-15 15:16:44","TRT01SDTM":"2020-06-14 21:16:44","TRT01EDTM":"2022-06-15 09:16:44","TRT02SDTM":"2022-06-15 09:16:44","TRT02EDTM":"2023-06-15 15:16:44","AP01SDTM":"2020-06-14 21:16:44","AP01EDTM":"2022-06-15 09:16:44","AP02SDTM":"2022-06-15 09:16:44","AP02EDTM":"2023-06-15 15:16:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-15","EOSDY":1096,"LSTALVDT":"2023-07-14","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7555,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.52104,"AVALU":"U/L","BASE2":6.10887,"BASE":27.50713,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.41217,"PCHG2":23.11679,"CHG":-19.98609,"PCHG":-72.65785,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-13 21:16:44","ADY":974,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-157","SUBJID":"id-157","SITEID":"USA-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":6.18035,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-06-14","TRTSDTM":"2020-06-14 21:16:44","TRTEDTM":"2023-06-15 15:16:44","TRT01SDTM":"2020-06-14 21:16:44","TRT01EDTM":"2022-06-15 09:16:44","TRT02SDTM":"2022-06-15 09:16:44","TRT02EDTM":"2023-06-15 15:16:44","AP01SDTM":"2020-06-14 21:16:44","AP01EDTM":"2022-06-15 09:16:44","AP02SDTM":"2022-06-15 09:16:44","AP02EDTM":"2023-06-15 15:16:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-15","EOSDY":1096,"LSTALVDT":"2023-07-14","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5803,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.9762,"AVALU":"U/L","BASE2":6.10887,"BASE":27.50713,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.86733,"PCHG2":227.00332,"CHG":-7.53093,"PCHG":-27.3781,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-24 21:16:44","ADY":1074,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-157","SUBJID":"id-157","SITEID":"USA-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":6.18035,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-06-14","TRTSDTM":"2020-06-14 21:16:44","TRTEDTM":"2023-06-15 15:16:44","TRT01SDTM":"2020-06-14 21:16:44","TRT01EDTM":"2022-06-15 09:16:44","TRT02SDTM":"2022-06-15 09:16:44","TRT02EDTM":"2023-06-15 15:16:44","AP01SDTM":"2020-06-14 21:16:44","AP01EDTM":"2022-06-15 09:16:44","AP02SDTM":"2022-06-15 09:16:44","AP02EDTM":"2023-06-15 15:16:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-15","EOSDY":1096,"LSTALVDT":"2023-07-14","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5783,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.53632,"AVALU":"mg/L","BASE2":8.53632,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-16 21:16:44","ADY":247,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-157","SUBJID":"id-157","SITEID":"USA-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":6.18035,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-06-14","TRTSDTM":"2020-06-14 21:16:44","TRTEDTM":"2023-06-15 15:16:44","TRT01SDTM":"2020-06-14 21:16:44","TRT01EDTM":"2022-06-15 09:16:44","TRT02SDTM":"2022-06-15 09:16:44","TRT02EDTM":"2023-06-15 15:16:44","AP01SDTM":"2020-06-14 21:16:44","AP01EDTM":"2022-06-15 09:16:44","AP02SDTM":"2022-06-15 09:16:44","AP02EDTM":"2023-06-15 15:16:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-15","EOSDY":1096,"LSTALVDT":"2023-07-14","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6297,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.5843,"AVALU":"mg/L","BASE2":8.53632,"BASE":8.5843,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.04798,"PCHG2":0.56208,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-29 21:16:44","ADY":319,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-157","SUBJID":"id-157","SITEID":"USA-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":6.18035,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-06-14","TRTSDTM":"2020-06-14 21:16:44","TRTEDTM":"2023-06-15 15:16:44","TRT01SDTM":"2020-06-14 21:16:44","TRT01EDTM":"2022-06-15 09:16:44","TRT02SDTM":"2022-06-15 09:16:44","TRT02EDTM":"2023-06-15 15:16:44","AP01SDTM":"2020-06-14 21:16:44","AP01EDTM":"2022-06-15 09:16:44","AP02SDTM":"2022-06-15 09:16:44","AP02EDTM":"2023-06-15 15:16:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-15","EOSDY":1096,"LSTALVDT":"2023-07-14","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3809,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.18732,"AVALU":"mg/L","BASE2":8.53632,"BASE":8.5843,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.651,"PCHG2":7.62624,"CHG":0.60302,"PCHG":7.02468,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-07 21:16:44","ADY":327,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-157","SUBJID":"id-157","SITEID":"USA-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":6.18035,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-06-14","TRTSDTM":"2020-06-14 21:16:44","TRTEDTM":"2023-06-15 15:16:44","TRT01SDTM":"2020-06-14 21:16:44","TRT01EDTM":"2022-06-15 09:16:44","TRT02SDTM":"2022-06-15 09:16:44","TRT02EDTM":"2023-06-15 15:16:44","AP01SDTM":"2020-06-14 21:16:44","AP01EDTM":"2022-06-15 09:16:44","AP02SDTM":"2022-06-15 09:16:44","AP02EDTM":"2023-06-15 15:16:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-15","EOSDY":1096,"LSTALVDT":"2023-07-14","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2177,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.76703,"AVALU":"mg/L","BASE2":8.53632,"BASE":8.5843,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.23072,"PCHG2":14.41742,"CHG":1.18274,"PCHG":13.77789,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-02 21:16:44","ADY":353,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-157","SUBJID":"id-157","SITEID":"USA-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":6.18035,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-06-14","TRTSDTM":"2020-06-14 21:16:44","TRTEDTM":"2023-06-15 15:16:44","TRT01SDTM":"2020-06-14 21:16:44","TRT01EDTM":"2022-06-15 09:16:44","TRT02SDTM":"2022-06-15 09:16:44","TRT02EDTM":"2023-06-15 15:16:44","AP01SDTM":"2020-06-14 21:16:44","AP01EDTM":"2022-06-15 09:16:44","AP02SDTM":"2022-06-15 09:16:44","AP02EDTM":"2023-06-15 15:16:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-15","EOSDY":1096,"LSTALVDT":"2023-07-14","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6603,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.13768,"AVALU":"mg/L","BASE2":8.53632,"BASE":8.5843,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.60137,"PCHG2":18.75946,"CHG":1.55339,"PCHG":18.09566,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-01-12 21:16:44","ADY":577,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-157","SUBJID":"id-157","SITEID":"USA-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":6.18035,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-06-14","TRTSDTM":"2020-06-14 21:16:44","TRTEDTM":"2023-06-15 15:16:44","TRT01SDTM":"2020-06-14 21:16:44","TRT01EDTM":"2022-06-15 09:16:44","TRT02SDTM":"2022-06-15 09:16:44","TRT02EDTM":"2023-06-15 15:16:44","AP01SDTM":"2020-06-14 21:16:44","AP01EDTM":"2022-06-15 09:16:44","AP02SDTM":"2022-06-15 09:16:44","AP02EDTM":"2023-06-15 15:16:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-15","EOSDY":1096,"LSTALVDT":"2023-07-14","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1839,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.1883,"AVALU":"mg/L","BASE2":8.53632,"BASE":8.5843,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.65199,"PCHG2":19.35244,"CHG":1.604,"PCHG":18.68533,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2023-02-13 21:16:44","ADY":974,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-157","SUBJID":"id-157","SITEID":"USA-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":6.18035,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-06-14","TRTSDTM":"2020-06-14 21:16:44","TRTEDTM":"2023-06-15 15:16:44","TRT01SDTM":"2020-06-14 21:16:44","TRT01EDTM":"2022-06-15 09:16:44","TRT02SDTM":"2022-06-15 09:16:44","TRT02EDTM":"2023-06-15 15:16:44","AP01SDTM":"2020-06-14 21:16:44","AP01EDTM":"2022-06-15 09:16:44","AP02SDTM":"2022-06-15 09:16:44","AP02EDTM":"2023-06-15 15:16:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-15","EOSDY":1096,"LSTALVDT":"2023-07-14","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7488,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.38337,"AVALU":"mg/L","BASE2":8.53632,"BASE":8.5843,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.84705,"PCHG2":9.92288,"CHG":0.79907,"PCHG":9.30848,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-24 21:16:44","ADY":1074,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-157","SUBJID":"id-157","SITEID":"USA-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":6.18035,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-06-14","TRTSDTM":"2020-06-14 21:16:44","TRTEDTM":"2023-06-15 15:16:44","TRT01SDTM":"2020-06-14 21:16:44","TRT01EDTM":"2022-06-15 09:16:44","TRT02SDTM":"2022-06-15 09:16:44","TRT02EDTM":"2023-06-15 15:16:44","AP01SDTM":"2020-06-14 21:16:44","AP01EDTM":"2022-06-15 09:16:44","AP02SDTM":"2022-06-15 09:16:44","AP02EDTM":"2023-06-15 15:16:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-15","EOSDY":1096,"LSTALVDT":"2023-07-14","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8046,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92666,"AVALU":"g/L","BASE2":2.92666,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-16 21:16:44","ADY":247,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-157","SUBJID":"id-157","SITEID":"USA-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":6.18035,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-06-14","TRTSDTM":"2020-06-14 21:16:44","TRTEDTM":"2023-06-15 15:16:44","TRT01SDTM":"2020-06-14 21:16:44","TRT01EDTM":"2022-06-15 09:16:44","TRT02SDTM":"2022-06-15 09:16:44","TRT02EDTM":"2023-06-15 15:16:44","AP01SDTM":"2020-06-14 21:16:44","AP01EDTM":"2022-06-15 09:16:44","AP02SDTM":"2022-06-15 09:16:44","AP02EDTM":"2023-06-15 15:16:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-15","EOSDY":1096,"LSTALVDT":"2023-07-14","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":801,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9145,"AVALU":"g/L","BASE2":2.92666,"BASE":2.9145,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.01216,"PCHG2":-0.41536,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-29 21:16:44","ADY":319,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-157","SUBJID":"id-157","SITEID":"USA-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":6.18035,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-06-14","TRTSDTM":"2020-06-14 21:16:44","TRTEDTM":"2023-06-15 15:16:44","TRT01SDTM":"2020-06-14 21:16:44","TRT01EDTM":"2022-06-15 09:16:44","TRT02SDTM":"2022-06-15 09:16:44","TRT02EDTM":"2023-06-15 15:16:44","AP01SDTM":"2020-06-14 21:16:44","AP01EDTM":"2022-06-15 09:16:44","AP02SDTM":"2022-06-15 09:16:44","AP02EDTM":"2023-06-15 15:16:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-15","EOSDY":1096,"LSTALVDT":"2023-07-14","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5656,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96383,"AVALU":"g/L","BASE2":2.92666,"BASE":2.9145,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03717,"PCHG2":1.27022,"CHG":0.04933,"PCHG":1.69261,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-07 21:16:44","ADY":327,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-157","SUBJID":"id-157","SITEID":"USA-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":6.18035,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-06-14","TRTSDTM":"2020-06-14 21:16:44","TRTEDTM":"2023-06-15 15:16:44","TRT01SDTM":"2020-06-14 21:16:44","TRT01EDTM":"2022-06-15 09:16:44","TRT02SDTM":"2022-06-15 09:16:44","TRT02EDTM":"2023-06-15 15:16:44","AP01SDTM":"2020-06-14 21:16:44","AP01EDTM":"2022-06-15 09:16:44","AP02SDTM":"2022-06-15 09:16:44","AP02EDTM":"2023-06-15 15:16:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-15","EOSDY":1096,"LSTALVDT":"2023-07-14","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4466,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84181,"AVALU":"g/L","BASE2":2.92666,"BASE":2.9145,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08485,"PCHG2":-2.89921,"CHG":-0.07269,"PCHG":-2.49421,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-02 21:16:44","ADY":353,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-157","SUBJID":"id-157","SITEID":"USA-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":6.18035,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-06-14","TRTSDTM":"2020-06-14 21:16:44","TRTEDTM":"2023-06-15 15:16:44","TRT01SDTM":"2020-06-14 21:16:44","TRT01EDTM":"2022-06-15 09:16:44","TRT02SDTM":"2022-06-15 09:16:44","TRT02EDTM":"2023-06-15 15:16:44","AP01SDTM":"2020-06-14 21:16:44","AP01EDTM":"2022-06-15 09:16:44","AP02SDTM":"2022-06-15 09:16:44","AP02EDTM":"2023-06-15 15:16:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-15","EOSDY":1096,"LSTALVDT":"2023-07-14","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2707,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05614,"AVALU":"g/L","BASE2":2.92666,"BASE":2.9145,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12948,"PCHG2":4.42423,"CHG":0.14164,"PCHG":4.85977,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-01-12 21:16:44","ADY":577,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-157","SUBJID":"id-157","SITEID":"USA-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":6.18035,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-06-14","TRTSDTM":"2020-06-14 21:16:44","TRTEDTM":"2023-06-15 15:16:44","TRT01SDTM":"2020-06-14 21:16:44","TRT01EDTM":"2022-06-15 09:16:44","TRT02SDTM":"2022-06-15 09:16:44","TRT02EDTM":"2023-06-15 15:16:44","AP01SDTM":"2020-06-14 21:16:44","AP01EDTM":"2022-06-15 09:16:44","AP02SDTM":"2022-06-15 09:16:44","AP02EDTM":"2023-06-15 15:16:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-15","EOSDY":1096,"LSTALVDT":"2023-07-14","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3923,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.78143,"AVALU":"g/L","BASE2":2.92666,"BASE":2.9145,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14523,"PCHG2":-4.96219,"CHG":-0.13307,"PCHG":-4.5658,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-13 21:16:44","ADY":974,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-157","SUBJID":"id-157","SITEID":"USA-11","AGE":50,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":6.18035,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"Y","RANDDT":"2020-06-14","TRTSDTM":"2020-06-14 21:16:44","TRTEDTM":"2023-06-15 15:16:44","TRT01SDTM":"2020-06-14 21:16:44","TRT01EDTM":"2022-06-15 09:16:44","TRT02SDTM":"2022-06-15 09:16:44","TRT02EDTM":"2023-06-15 15:16:44","AP01SDTM":"2020-06-14 21:16:44","AP01EDTM":"2022-06-15 09:16:44","AP02SDTM":"2022-06-15 09:16:44","AP02EDTM":"2023-06-15 15:16:44","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-06-15","EOSDY":1096,"LSTALVDT":"2023-07-14","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5157,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01821,"AVALU":"g/L","BASE2":2.92666,"BASE":2.9145,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09155,"PCHG2":3.12824,"CHG":0.10371,"PCHG":3.55838,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2023-05-24 21:16:44","ADY":1074,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-203","SUBJID":"id-203","SITEID":"USA-11","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.60082,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-29 09:35:30","TRTEDTM":"2022-02-15 22:34:47","TRT01SDTM":"2019-12-29 09:35:30","TRT01EDTM":"2021-02-15 16:34:47","TRT02SDTM":"2021-02-15 16:34:47","TRT02EDTM":"2022-02-15 22:34:47","AP01SDTM":"2019-12-29 09:35:30","AP01EDTM":"2021-02-15 16:34:47","AP02SDTM":"2021-02-15 16:34:47","AP02EDTM":"2022-02-15 22:34:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-10","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3459,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.80757,"AVALU":"U/L","BASE2":11.80757,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-20 09:35:30","ADY":22,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-203","SUBJID":"id-203","SITEID":"USA-11","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.60082,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-29 09:35:30","TRTEDTM":"2022-02-15 22:34:47","TRT01SDTM":"2019-12-29 09:35:30","TRT01EDTM":"2021-02-15 16:34:47","TRT02SDTM":"2021-02-15 16:34:47","TRT02EDTM":"2022-02-15 22:34:47","AP01SDTM":"2019-12-29 09:35:30","AP01EDTM":"2021-02-15 16:34:47","AP02SDTM":"2021-02-15 16:34:47","AP02EDTM":"2022-02-15 22:34:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-10","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8037,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":35.03799,"AVALU":"U/L","BASE2":11.80757,"BASE":35.03799,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":23.23042,"PCHG2":196.74178,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-10 09:35:30","ADY":43,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-203","SUBJID":"id-203","SITEID":"USA-11","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.60082,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-29 09:35:30","TRTEDTM":"2022-02-15 22:34:47","TRT01SDTM":"2019-12-29 09:35:30","TRT01EDTM":"2021-02-15 16:34:47","TRT02SDTM":"2021-02-15 16:34:47","TRT02EDTM":"2022-02-15 22:34:47","AP01SDTM":"2019-12-29 09:35:30","AP01EDTM":"2021-02-15 16:34:47","AP02SDTM":"2021-02-15 16:34:47","AP02EDTM":"2022-02-15 22:34:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-10","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4499,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.26365,"AVALU":"U/L","BASE2":11.80757,"BASE":35.03799,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.54391,"PCHG2":-30.01392,"CHG":-26.77434,"PCHG":-76.41516,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-08 09:35:30","ADY":131,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-203","SUBJID":"id-203","SITEID":"USA-11","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.60082,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-29 09:35:30","TRTEDTM":"2022-02-15 22:34:47","TRT01SDTM":"2019-12-29 09:35:30","TRT01EDTM":"2021-02-15 16:34:47","TRT02SDTM":"2021-02-15 16:34:47","TRT02EDTM":"2022-02-15 22:34:47","AP01SDTM":"2019-12-29 09:35:30","AP01EDTM":"2021-02-15 16:34:47","AP02SDTM":"2021-02-15 16:34:47","AP02EDTM":"2022-02-15 22:34:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-10","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2040,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.18204,"AVALU":"U/L","BASE2":11.80757,"BASE":35.03799,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.62553,"PCHG2":-98.45824,"CHG":-34.85595,"PCHG":-99.48044,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-02-10 09:35:30","ADY":409,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-203","SUBJID":"id-203","SITEID":"USA-11","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.60082,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-29 09:35:30","TRTEDTM":"2022-02-15 22:34:47","TRT01SDTM":"2019-12-29 09:35:30","TRT01EDTM":"2021-02-15 16:34:47","TRT02SDTM":"2021-02-15 16:34:47","TRT02EDTM":"2022-02-15 22:34:47","AP01SDTM":"2019-12-29 09:35:30","AP01EDTM":"2021-02-15 16:34:47","AP02SDTM":"2021-02-15 16:34:47","AP02EDTM":"2022-02-15 22:34:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-10","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3051,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.79493,"AVALU":"U/L","BASE2":11.80757,"BASE":35.03799,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.98736,"PCHG2":25.30036,"CHG":-20.24307,"PCHG":-57.77462,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-30 09:35:30","ADY":457,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-203","SUBJID":"id-203","SITEID":"USA-11","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.60082,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-29 09:35:30","TRTEDTM":"2022-02-15 22:34:47","TRT01SDTM":"2019-12-29 09:35:30","TRT01EDTM":"2021-02-15 16:34:47","TRT02SDTM":"2021-02-15 16:34:47","TRT02EDTM":"2022-02-15 22:34:47","AP01SDTM":"2019-12-29 09:35:30","AP01EDTM":"2021-02-15 16:34:47","AP02SDTM":"2021-02-15 16:34:47","AP02EDTM":"2022-02-15 22:34:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-10","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5059,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.97345,"AVALU":"U/L","BASE2":11.80757,"BASE":35.03799,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.16588,"PCHG2":69.15799,"CHG":-15.06454,"PCHG":-42.99488,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-13 09:35:30","ADY":624,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-203","SUBJID":"id-203","SITEID":"USA-11","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.60082,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-29 09:35:30","TRTEDTM":"2022-02-15 22:34:47","TRT01SDTM":"2019-12-29 09:35:30","TRT01EDTM":"2021-02-15 16:34:47","TRT02SDTM":"2021-02-15 16:34:47","TRT02EDTM":"2022-02-15 22:34:47","AP01SDTM":"2019-12-29 09:35:30","AP01EDTM":"2021-02-15 16:34:47","AP02SDTM":"2021-02-15 16:34:47","AP02EDTM":"2022-02-15 22:34:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-10","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6608,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.19871,"AVALU":"U/L","BASE2":11.80757,"BASE":35.03799,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.60886,"PCHG2":-22.09479,"CHG":-25.83928,"PCHG":-73.74646,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-29 09:35:30","ADY":640,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-203","SUBJID":"id-203","SITEID":"USA-11","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.60082,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-29 09:35:30","TRTEDTM":"2022-02-15 22:34:47","TRT01SDTM":"2019-12-29 09:35:30","TRT01EDTM":"2021-02-15 16:34:47","TRT02SDTM":"2021-02-15 16:34:47","TRT02EDTM":"2022-02-15 22:34:47","AP01SDTM":"2019-12-29 09:35:30","AP01EDTM":"2021-02-15 16:34:47","AP02SDTM":"2021-02-15 16:34:47","AP02EDTM":"2022-02-15 22:34:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-10","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":355,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.70404,"AVALU":"mg/L","BASE2":9.70404,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-20 09:35:30","ADY":22,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-203","SUBJID":"id-203","SITEID":"USA-11","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.60082,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-29 09:35:30","TRTEDTM":"2022-02-15 22:34:47","TRT01SDTM":"2019-12-29 09:35:30","TRT01EDTM":"2021-02-15 16:34:47","TRT02SDTM":"2021-02-15 16:34:47","TRT02EDTM":"2022-02-15 22:34:47","AP01SDTM":"2019-12-29 09:35:30","AP01EDTM":"2021-02-15 16:34:47","AP02SDTM":"2021-02-15 16:34:47","AP02EDTM":"2022-02-15 22:34:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-10","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6553,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.4112,"AVALU":"mg/L","BASE2":9.70404,"BASE":8.4112,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.29284,"PCHG2":-13.32269,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-10 09:35:30","ADY":43,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-203","SUBJID":"id-203","SITEID":"USA-11","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.60082,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-29 09:35:30","TRTEDTM":"2022-02-15 22:34:47","TRT01SDTM":"2019-12-29 09:35:30","TRT01EDTM":"2021-02-15 16:34:47","TRT02SDTM":"2021-02-15 16:34:47","TRT02EDTM":"2022-02-15 22:34:47","AP01SDTM":"2019-12-29 09:35:30","AP01EDTM":"2021-02-15 16:34:47","AP02SDTM":"2021-02-15 16:34:47","AP02EDTM":"2022-02-15 22:34:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-10","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2767,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.78632,"AVALU":"mg/L","BASE2":9.70404,"BASE":8.4112,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08228,"PCHG2":0.84789,"CHG":1.37512,"PCHG":16.34866,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-08 09:35:30","ADY":131,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-203","SUBJID":"id-203","SITEID":"USA-11","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.60082,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-29 09:35:30","TRTEDTM":"2022-02-15 22:34:47","TRT01SDTM":"2019-12-29 09:35:30","TRT01EDTM":"2021-02-15 16:34:47","TRT02SDTM":"2021-02-15 16:34:47","TRT02EDTM":"2022-02-15 22:34:47","AP01SDTM":"2019-12-29 09:35:30","AP01EDTM":"2021-02-15 16:34:47","AP02SDTM":"2021-02-15 16:34:47","AP02EDTM":"2022-02-15 22:34:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-10","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7415,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.26889,"AVALU":"mg/L","BASE2":9.70404,"BASE":8.4112,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.43515,"PCHG2":-25.09416,"CHG":-1.14231,"PCHG":-13.58081,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-02-10 09:35:30","ADY":409,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-203","SUBJID":"id-203","SITEID":"USA-11","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.60082,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-29 09:35:30","TRTEDTM":"2022-02-15 22:34:47","TRT01SDTM":"2019-12-29 09:35:30","TRT01EDTM":"2021-02-15 16:34:47","TRT02SDTM":"2021-02-15 16:34:47","TRT02EDTM":"2022-02-15 22:34:47","AP01SDTM":"2019-12-29 09:35:30","AP01EDTM":"2021-02-15 16:34:47","AP02SDTM":"2021-02-15 16:34:47","AP02EDTM":"2022-02-15 22:34:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-10","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1916,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.37174,"AVALU":"mg/L","BASE2":9.70404,"BASE":8.4112,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.3323,"PCHG2":-13.72932,"CHG":-0.03946,"PCHG":-0.46913,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-30 09:35:30","ADY":457,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-203","SUBJID":"id-203","SITEID":"USA-11","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.60082,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-29 09:35:30","TRTEDTM":"2022-02-15 22:34:47","TRT01SDTM":"2019-12-29 09:35:30","TRT01EDTM":"2021-02-15 16:34:47","TRT02SDTM":"2021-02-15 16:34:47","TRT02EDTM":"2022-02-15 22:34:47","AP01SDTM":"2019-12-29 09:35:30","AP01EDTM":"2021-02-15 16:34:47","AP02SDTM":"2021-02-15 16:34:47","AP02EDTM":"2022-02-15 22:34:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-10","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7815,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.2094,"AVALU":"mg/L","BASE2":9.70404,"BASE":8.4112,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.49465,"PCHG2":-5.09731,"CHG":0.79819,"PCHG":9.48965,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-13 09:35:30","ADY":624,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-203","SUBJID":"id-203","SITEID":"USA-11","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.60082,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-29 09:35:30","TRTEDTM":"2022-02-15 22:34:47","TRT01SDTM":"2019-12-29 09:35:30","TRT01EDTM":"2021-02-15 16:34:47","TRT02SDTM":"2021-02-15 16:34:47","TRT02EDTM":"2022-02-15 22:34:47","AP01SDTM":"2019-12-29 09:35:30","AP01EDTM":"2021-02-15 16:34:47","AP02SDTM":"2021-02-15 16:34:47","AP02EDTM":"2022-02-15 22:34:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-10","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":453,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.54808,"AVALU":"mg/L","BASE2":9.70404,"BASE":8.4112,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15596,"PCHG2":-1.60718,"CHG":1.13688,"PCHG":13.51624,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-29 09:35:30","ADY":640,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-203","SUBJID":"id-203","SITEID":"USA-11","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.60082,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-29 09:35:30","TRTEDTM":"2022-02-15 22:34:47","TRT01SDTM":"2019-12-29 09:35:30","TRT01EDTM":"2021-02-15 16:34:47","TRT02SDTM":"2021-02-15 16:34:47","TRT02EDTM":"2022-02-15 22:34:47","AP01SDTM":"2019-12-29 09:35:30","AP01EDTM":"2021-02-15 16:34:47","AP02SDTM":"2021-02-15 16:34:47","AP02EDTM":"2022-02-15 22:34:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-10","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3799,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86484,"AVALU":"g/L","BASE2":2.86484,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-20 09:35:30","ADY":22,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-203","SUBJID":"id-203","SITEID":"USA-11","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.60082,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-29 09:35:30","TRTEDTM":"2022-02-15 22:34:47","TRT01SDTM":"2019-12-29 09:35:30","TRT01EDTM":"2021-02-15 16:34:47","TRT02SDTM":"2021-02-15 16:34:47","TRT02EDTM":"2022-02-15 22:34:47","AP01SDTM":"2019-12-29 09:35:30","AP01EDTM":"2021-02-15 16:34:47","AP02SDTM":"2021-02-15 16:34:47","AP02EDTM":"2022-02-15 22:34:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-10","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1552,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.6775,"AVALU":"g/L","BASE2":2.86484,"BASE":2.6775,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.18734,"PCHG2":-6.53941,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-10 09:35:30","ADY":43,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-203","SUBJID":"id-203","SITEID":"USA-11","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.60082,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-29 09:35:30","TRTEDTM":"2022-02-15 22:34:47","TRT01SDTM":"2019-12-29 09:35:30","TRT01EDTM":"2021-02-15 16:34:47","TRT02SDTM":"2021-02-15 16:34:47","TRT02EDTM":"2022-02-15 22:34:47","AP01SDTM":"2019-12-29 09:35:30","AP01EDTM":"2021-02-15 16:34:47","AP02SDTM":"2021-02-15 16:34:47","AP02EDTM":"2022-02-15 22:34:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-10","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8344,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96128,"AVALU":"g/L","BASE2":2.86484,"BASE":2.6775,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09644,"PCHG2":3.36638,"CHG":0.28379,"PCHG":10.5989,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-08 09:35:30","ADY":131,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-203","SUBJID":"id-203","SITEID":"USA-11","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.60082,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-29 09:35:30","TRTEDTM":"2022-02-15 22:34:47","TRT01SDTM":"2019-12-29 09:35:30","TRT01EDTM":"2021-02-15 16:34:47","TRT02SDTM":"2021-02-15 16:34:47","TRT02EDTM":"2022-02-15 22:34:47","AP01SDTM":"2019-12-29 09:35:30","AP01EDTM":"2021-02-15 16:34:47","AP02SDTM":"2021-02-15 16:34:47","AP02EDTM":"2022-02-15 22:34:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-10","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":750,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95005,"AVALU":"g/L","BASE2":2.86484,"BASE":2.6775,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0852,"PCHG2":2.9741,"CHG":0.27255,"PCHG":10.17916,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-10 09:35:30","ADY":409,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-203","SUBJID":"id-203","SITEID":"USA-11","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.60082,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-29 09:35:30","TRTEDTM":"2022-02-15 22:34:47","TRT01SDTM":"2019-12-29 09:35:30","TRT01EDTM":"2021-02-15 16:34:47","TRT02SDTM":"2021-02-15 16:34:47","TRT02EDTM":"2022-02-15 22:34:47","AP01SDTM":"2019-12-29 09:35:30","AP01EDTM":"2021-02-15 16:34:47","AP02SDTM":"2021-02-15 16:34:47","AP02EDTM":"2022-02-15 22:34:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-10","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1050,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76236,"AVALU":"g/L","BASE2":2.86484,"BASE":2.6775,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10248,"PCHG2":-3.57722,"CHG":0.08486,"PCHG":3.16944,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-30 09:35:30","ADY":457,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-203","SUBJID":"id-203","SITEID":"USA-11","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.60082,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-29 09:35:30","TRTEDTM":"2022-02-15 22:34:47","TRT01SDTM":"2019-12-29 09:35:30","TRT01EDTM":"2021-02-15 16:34:47","TRT02SDTM":"2021-02-15 16:34:47","TRT02EDTM":"2022-02-15 22:34:47","AP01SDTM":"2019-12-29 09:35:30","AP01EDTM":"2021-02-15 16:34:47","AP02SDTM":"2021-02-15 16:34:47","AP02EDTM":"2022-02-15 22:34:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-10","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":755,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.10035,"AVALU":"g/L","BASE2":2.86484,"BASE":2.6775,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.23551,"PCHG2":8.22055,"CHG":0.42285,"PCHG":15.7927,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-09-13 09:35:30","ADY":624,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-203","SUBJID":"id-203","SITEID":"USA-11","AGE":41,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":5.60082,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-12-26","TRTSDTM":"2019-12-29 09:35:30","TRTEDTM":"2022-02-15 22:34:47","TRT01SDTM":"2019-12-29 09:35:30","TRT01EDTM":"2021-02-15 16:34:47","TRT02SDTM":"2021-02-15 16:34:47","TRT02EDTM":"2022-02-15 22:34:47","AP01SDTM":"2019-12-29 09:35:30","AP01EDTM":"2021-02-15 16:34:47","AP02SDTM":"2021-02-15 16:34:47","AP02EDTM":"2022-02-15 22:34:47","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-15","EOSDY":780,"DCSREAS":"WITHDRAWAL BY PARENT/GUARDIAN","LSTALVDT":"2022-03-10","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7547,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92327,"AVALU":"g/L","BASE2":2.86484,"BASE":2.6775,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05843,"PCHG2":2.03944,"CHG":0.24577,"PCHG":9.1791,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-29 09:35:30","ADY":640,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-224","SUBJID":"id-224","SITEID":"USA-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.42717,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 21:27:55","TRTEDTM":"2023-11-18 15:27:55","TRT01SDTM":"2020-11-17 21:27:55","TRT01EDTM":"2022-11-18 09:27:55","TRT02SDTM":"2022-11-18 09:27:55","TRT02EDTM":"2023-11-18 15:27:55","AP01SDTM":"2020-11-17 21:27:55","AP01EDTM":"2022-11-18 09:27:55","AP02SDTM":"2022-11-18 09:27:55","AP02EDTM":"2023-11-18 15:27:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-14","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2354,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.79963,"AVALU":"U/L","BASE2":21.79963,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-21 21:27:55","ADY":550,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-224","SUBJID":"id-224","SITEID":"USA-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.42717,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 21:27:55","TRTEDTM":"2023-11-18 15:27:55","TRT01SDTM":"2020-11-17 21:27:55","TRT01EDTM":"2022-11-18 09:27:55","TRT02SDTM":"2022-11-18 09:27:55","TRT02EDTM":"2023-11-18 15:27:55","AP01SDTM":"2020-11-17 21:27:55","AP01EDTM":"2022-11-18 09:27:55","AP02SDTM":"2022-11-18 09:27:55","AP02EDTM":"2023-11-18 15:27:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-14","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1203,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.95263,"AVALU":"U/L","BASE2":21.79963,"BASE":30.95263,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":9.15301,"PCHG2":41.98698,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-24 21:27:55","ADY":584,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-224","SUBJID":"id-224","SITEID":"USA-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.42717,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 21:27:55","TRTEDTM":"2023-11-18 15:27:55","TRT01SDTM":"2020-11-17 21:27:55","TRT01EDTM":"2022-11-18 09:27:55","TRT02SDTM":"2022-11-18 09:27:55","TRT02EDTM":"2023-11-18 15:27:55","AP01SDTM":"2020-11-17 21:27:55","AP01EDTM":"2022-11-18 09:27:55","AP02SDTM":"2022-11-18 09:27:55","AP02EDTM":"2023-11-18 15:27:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-14","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8028,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.36873,"AVALU":"U/L","BASE2":21.79963,"BASE":30.95263,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.4309,"PCHG2":-34.08729,"CHG":-16.58391,"PCHG":-53.57834,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-19 21:27:55","ADY":609,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-224","SUBJID":"id-224","SITEID":"USA-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.42717,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 21:27:55","TRTEDTM":"2023-11-18 15:27:55","TRT01SDTM":"2020-11-17 21:27:55","TRT01EDTM":"2022-11-18 09:27:55","TRT02SDTM":"2022-11-18 09:27:55","TRT02EDTM":"2023-11-18 15:27:55","AP01SDTM":"2020-11-17 21:27:55","AP01EDTM":"2022-11-18 09:27:55","AP02SDTM":"2022-11-18 09:27:55","AP02EDTM":"2023-11-18 15:27:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-14","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1419,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.04949,"AVALU":"U/L","BASE2":21.79963,"BASE":30.95263,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.75014,"PCHG2":-35.55169,"CHG":-16.90314,"PCHG":-54.6097,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-19 21:27:55","ADY":671,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-224","SUBJID":"id-224","SITEID":"USA-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.42717,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 21:27:55","TRTEDTM":"2023-11-18 15:27:55","TRT01SDTM":"2020-11-17 21:27:55","TRT01EDTM":"2022-11-18 09:27:55","TRT02SDTM":"2022-11-18 09:27:55","TRT02EDTM":"2023-11-18 15:27:55","AP01SDTM":"2020-11-17 21:27:55","AP01EDTM":"2022-11-18 09:27:55","AP02SDTM":"2022-11-18 09:27:55","AP02EDTM":"2023-11-18 15:27:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-14","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6060,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.00452,"AVALU":"U/L","BASE2":21.79963,"BASE":30.95263,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.79511,"PCHG2":-44.93246,"CHG":-18.94811,"PCHG":-61.21649,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-15 21:27:55","ADY":789,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-224","SUBJID":"id-224","SITEID":"USA-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.42717,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 21:27:55","TRTEDTM":"2023-11-18 15:27:55","TRT01SDTM":"2020-11-17 21:27:55","TRT01EDTM":"2022-11-18 09:27:55","TRT02SDTM":"2022-11-18 09:27:55","TRT02EDTM":"2023-11-18 15:27:55","AP01SDTM":"2020-11-17 21:27:55","AP01EDTM":"2022-11-18 09:27:55","AP02SDTM":"2022-11-18 09:27:55","AP02EDTM":"2023-11-18 15:27:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-14","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7520,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.57984,"AVALU":"U/L","BASE2":21.79963,"BASE":30.95263,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.78022,"PCHG2":21.92798,"CHG":-4.37279,"PCHG":-14.12735,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-15 21:27:55","ADY":879,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-224","SUBJID":"id-224","SITEID":"USA-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.42717,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 21:27:55","TRTEDTM":"2023-11-18 15:27:55","TRT01SDTM":"2020-11-17 21:27:55","TRT01EDTM":"2022-11-18 09:27:55","TRT02SDTM":"2022-11-18 09:27:55","TRT02EDTM":"2023-11-18 15:27:55","AP01SDTM":"2020-11-17 21:27:55","AP01EDTM":"2022-11-18 09:27:55","AP02SDTM":"2022-11-18 09:27:55","AP02EDTM":"2023-11-18 15:27:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-14","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1589,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.7429,"AVALU":"U/L","BASE2":21.79963,"BASE":30.95263,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05673,"PCHG2":-0.26024,"CHG":-9.20974,"PCHG":-29.75429,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-10-07 21:27:55","ADY":1054,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-224","SUBJID":"id-224","SITEID":"USA-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.42717,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 21:27:55","TRTEDTM":"2023-11-18 15:27:55","TRT01SDTM":"2020-11-17 21:27:55","TRT01EDTM":"2022-11-18 09:27:55","TRT02SDTM":"2022-11-18 09:27:55","TRT02EDTM":"2023-11-18 15:27:55","AP01SDTM":"2020-11-17 21:27:55","AP01EDTM":"2022-11-18 09:27:55","AP02SDTM":"2022-11-18 09:27:55","AP02EDTM":"2023-11-18 15:27:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-14","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1051,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.2275,"AVALU":"mg/L","BASE2":9.2275,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-21 21:27:55","ADY":550,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-224","SUBJID":"id-224","SITEID":"USA-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.42717,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 21:27:55","TRTEDTM":"2023-11-18 15:27:55","TRT01SDTM":"2020-11-17 21:27:55","TRT01EDTM":"2022-11-18 09:27:55","TRT02SDTM":"2022-11-18 09:27:55","TRT02EDTM":"2023-11-18 15:27:55","AP01SDTM":"2020-11-17 21:27:55","AP01EDTM":"2022-11-18 09:27:55","AP02SDTM":"2022-11-18 09:27:55","AP02EDTM":"2023-11-18 15:27:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-14","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5923,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.82261,"AVALU":"mg/L","BASE2":9.2275,"BASE":8.82261,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.40489,"PCHG2":-4.38784,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-24 21:27:55","ADY":584,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-224","SUBJID":"id-224","SITEID":"USA-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.42717,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 21:27:55","TRTEDTM":"2023-11-18 15:27:55","TRT01SDTM":"2020-11-17 21:27:55","TRT01EDTM":"2022-11-18 09:27:55","TRT02SDTM":"2022-11-18 09:27:55","TRT02EDTM":"2023-11-18 15:27:55","AP01SDTM":"2020-11-17 21:27:55","AP01EDTM":"2022-11-18 09:27:55","AP02SDTM":"2022-11-18 09:27:55","AP02EDTM":"2023-11-18 15:27:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-14","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":961,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.65115,"AVALU":"mg/L","BASE2":9.2275,"BASE":8.82261,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.42365,"PCHG2":4.5912,"CHG":0.82854,"PCHG":9.39111,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-07-19 21:27:55","ADY":609,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-224","SUBJID":"id-224","SITEID":"USA-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.42717,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 21:27:55","TRTEDTM":"2023-11-18 15:27:55","TRT01SDTM":"2020-11-17 21:27:55","TRT01EDTM":"2022-11-18 09:27:55","TRT02SDTM":"2022-11-18 09:27:55","TRT02EDTM":"2023-11-18 15:27:55","AP01SDTM":"2020-11-17 21:27:55","AP01EDTM":"2022-11-18 09:27:55","AP02SDTM":"2022-11-18 09:27:55","AP02EDTM":"2023-11-18 15:27:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-14","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4975,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.78508,"AVALU":"mg/L","BASE2":9.2275,"BASE":8.82261,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.55758,"PCHG2":6.04263,"CHG":0.96247,"PCHG":10.90914,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-19 21:27:55","ADY":671,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-224","SUBJID":"id-224","SITEID":"USA-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.42717,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 21:27:55","TRTEDTM":"2023-11-18 15:27:55","TRT01SDTM":"2020-11-17 21:27:55","TRT01EDTM":"2022-11-18 09:27:55","TRT02SDTM":"2022-11-18 09:27:55","TRT02EDTM":"2023-11-18 15:27:55","AP01SDTM":"2020-11-17 21:27:55","AP01EDTM":"2022-11-18 09:27:55","AP02SDTM":"2022-11-18 09:27:55","AP02EDTM":"2023-11-18 15:27:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-14","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4163,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.43147,"AVALU":"mg/L","BASE2":9.2275,"BASE":8.82261,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.20397,"PCHG2":2.21045,"CHG":0.60886,"PCHG":6.9011,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-15 21:27:55","ADY":789,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-224","SUBJID":"id-224","SITEID":"USA-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.42717,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 21:27:55","TRTEDTM":"2023-11-18 15:27:55","TRT01SDTM":"2020-11-17 21:27:55","TRT01EDTM":"2022-11-18 09:27:55","TRT02SDTM":"2022-11-18 09:27:55","TRT02EDTM":"2023-11-18 15:27:55","AP01SDTM":"2020-11-17 21:27:55","AP01EDTM":"2022-11-18 09:27:55","AP02SDTM":"2022-11-18 09:27:55","AP02EDTM":"2023-11-18 15:27:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-14","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8253,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.92039,"AVALU":"mg/L","BASE2":9.2275,"BASE":8.82261,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.69289,"PCHG2":7.50897,"CHG":1.09778,"PCHG":12.44277,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-15 21:27:55","ADY":879,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-224","SUBJID":"id-224","SITEID":"USA-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.42717,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 21:27:55","TRTEDTM":"2023-11-18 15:27:55","TRT01SDTM":"2020-11-17 21:27:55","TRT01EDTM":"2022-11-18 09:27:55","TRT02SDTM":"2022-11-18 09:27:55","TRT02EDTM":"2023-11-18 15:27:55","AP01SDTM":"2020-11-17 21:27:55","AP01EDTM":"2022-11-18 09:27:55","AP02SDTM":"2022-11-18 09:27:55","AP02EDTM":"2023-11-18 15:27:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-14","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1064,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.73318,"AVALU":"mg/L","BASE2":9.2275,"BASE":8.82261,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.50568,"PCHG2":27.15454,"CHG":2.91057,"PCHG":32.98992,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2023-10-07 21:27:55","ADY":1054,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-224","SUBJID":"id-224","SITEID":"USA-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.42717,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 21:27:55","TRTEDTM":"2023-11-18 15:27:55","TRT01SDTM":"2020-11-17 21:27:55","TRT01EDTM":"2022-11-18 09:27:55","TRT02SDTM":"2022-11-18 09:27:55","TRT02EDTM":"2023-11-18 15:27:55","AP01SDTM":"2020-11-17 21:27:55","AP01EDTM":"2022-11-18 09:27:55","AP02SDTM":"2022-11-18 09:27:55","AP02EDTM":"2023-11-18 15:27:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-14","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8029,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00255,"AVALU":"g/L","BASE2":3.00255,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-05-21 21:27:55","ADY":550,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-224","SUBJID":"id-224","SITEID":"USA-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.42717,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 21:27:55","TRTEDTM":"2023-11-18 15:27:55","TRT01SDTM":"2020-11-17 21:27:55","TRT01EDTM":"2022-11-18 09:27:55","TRT02SDTM":"2022-11-18 09:27:55","TRT02EDTM":"2023-11-18 15:27:55","AP01SDTM":"2020-11-17 21:27:55","AP01EDTM":"2022-11-18 09:27:55","AP02SDTM":"2022-11-18 09:27:55","AP02EDTM":"2023-11-18 15:27:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-14","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2616,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86095,"AVALU":"g/L","BASE2":3.00255,"BASE":2.86095,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.1416,"PCHG2":-4.71608,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-24 21:27:55","ADY":584,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-224","SUBJID":"id-224","SITEID":"USA-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.42717,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 21:27:55","TRTEDTM":"2023-11-18 15:27:55","TRT01SDTM":"2020-11-17 21:27:55","TRT01EDTM":"2022-11-18 09:27:55","TRT02SDTM":"2022-11-18 09:27:55","TRT02EDTM":"2023-11-18 15:27:55","AP01SDTM":"2020-11-17 21:27:55","AP01EDTM":"2022-11-18 09:27:55","AP02SDTM":"2022-11-18 09:27:55","AP02EDTM":"2023-11-18 15:27:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-14","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2107,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.15165,"AVALU":"g/L","BASE2":3.00255,"BASE":2.86095,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1491,"PCHG2":4.96571,"CHG":0.2907,"PCHG":10.16099,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-07-19 21:27:55","ADY":609,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-224","SUBJID":"id-224","SITEID":"USA-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.42717,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 21:27:55","TRTEDTM":"2023-11-18 15:27:55","TRT01SDTM":"2020-11-17 21:27:55","TRT01EDTM":"2022-11-18 09:27:55","TRT02SDTM":"2022-11-18 09:27:55","TRT02EDTM":"2023-11-18 15:27:55","AP01SDTM":"2020-11-17 21:27:55","AP01EDTM":"2022-11-18 09:27:55","AP02SDTM":"2022-11-18 09:27:55","AP02EDTM":"2023-11-18 15:27:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-14","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5631,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84401,"AVALU":"g/L","BASE2":3.00255,"BASE":2.86095,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15855,"PCHG2":-5.28034,"CHG":-0.01694,"PCHG":-0.59219,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-19 21:27:55","ADY":671,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-224","SUBJID":"id-224","SITEID":"USA-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.42717,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 21:27:55","TRTEDTM":"2023-11-18 15:27:55","TRT01SDTM":"2020-11-17 21:27:55","TRT01EDTM":"2022-11-18 09:27:55","TRT02SDTM":"2022-11-18 09:27:55","TRT02EDTM":"2023-11-18 15:27:55","AP01SDTM":"2020-11-17 21:27:55","AP01EDTM":"2022-11-18 09:27:55","AP02SDTM":"2022-11-18 09:27:55","AP02EDTM":"2023-11-18 15:27:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-14","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2983,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84629,"AVALU":"g/L","BASE2":3.00255,"BASE":2.86095,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.15626,"PCHG2":-5.20416,"CHG":-0.01465,"PCHG":-0.51223,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-15 21:27:55","ADY":789,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-224","SUBJID":"id-224","SITEID":"USA-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.42717,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 21:27:55","TRTEDTM":"2023-11-18 15:27:55","TRT01SDTM":"2020-11-17 21:27:55","TRT01EDTM":"2022-11-18 09:27:55","TRT02SDTM":"2022-11-18 09:27:55","TRT02EDTM":"2023-11-18 15:27:55","AP01SDTM":"2020-11-17 21:27:55","AP01EDTM":"2022-11-18 09:27:55","AP02SDTM":"2022-11-18 09:27:55","AP02EDTM":"2023-11-18 15:27:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-14","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7889,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82309,"AVALU":"g/L","BASE2":3.00255,"BASE":2.86095,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.17947,"PCHG2":-5.97714,"CHG":-0.03786,"PCHG":-1.32347,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-15 21:27:55","ADY":879,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-224","SUBJID":"id-224","SITEID":"USA-11","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":6.42717,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-11-13","TRTSDTM":"2020-11-17 21:27:55","TRTEDTM":"2023-11-18 15:27:55","TRT01SDTM":"2020-11-17 21:27:55","TRT01EDTM":"2022-11-18 09:27:55","TRT02SDTM":"2022-11-18 09:27:55","TRT02EDTM":"2023-11-18 15:27:55","AP01SDTM":"2020-11-17 21:27:55","AP01EDTM":"2022-11-18 09:27:55","AP02SDTM":"2022-11-18 09:27:55","AP02EDTM":"2023-11-18 15:27:55","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-18","EOSDY":1096,"LSTALVDT":"2023-12-14","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2589,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.72444,"AVALU":"g/L","BASE2":3.00255,"BASE":2.86095,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.27811,"PCHG2":-9.26251,"CHG":-0.13651,"PCHG":-4.77146,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-10-07 21:27:55","ADY":1054,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-238","SUBJID":"id-238","SITEID":"USA-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.0392,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-15","TRTSDTM":"2019-12-17 16:17:31","TRT01SDTM":"2019-12-17 16:17:31","AP01SDTM":"2019-12-17 16:17:31","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1265,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.1254,"AVALU":"U/L","BASE2":3.1254,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-4","ADTM":"2020-04-04 16:17:31","ADY":109,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-238","SUBJID":"id-238","SITEID":"USA-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.0392,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-15","TRTSDTM":"2019-12-17 16:17:31","TRT01SDTM":"2019-12-17 16:17:31","AP01SDTM":"2019-12-17 16:17:31","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":651,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.96932,"AVALU":"U/L","BASE2":3.1254,"BASE":5.96932,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.84393,"PCHG2":90.99406,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-4","BTOXGR":"-4","ADTM":"2020-11-04 16:17:31","ADY":323,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-238","SUBJID":"id-238","SITEID":"USA-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.0392,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-15","TRTSDTM":"2019-12-17 16:17:31","TRT01SDTM":"2019-12-17 16:17:31","AP01SDTM":"2019-12-17 16:17:31","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1640,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.64841,"AVALU":"U/L","BASE2":3.1254,"BASE":5.96932,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.52301,"PCHG2":208.70989,"CHG":3.67909,"PCHG":61.63324,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2020-11-21 16:17:31","ADY":340,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-238","SUBJID":"id-238","SITEID":"USA-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.0392,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-15","TRTSDTM":"2019-12-17 16:17:31","TRT01SDTM":"2019-12-17 16:17:31","AP01SDTM":"2019-12-17 16:17:31","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2546,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.21012,"AVALU":"U/L","BASE2":3.1254,"BASE":5.96932,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.08472,"PCHG2":162.6905,"CHG":2.2408,"PCHG":37.53857,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2020-12-22 16:17:31","ADY":371,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-238","SUBJID":"id-238","SITEID":"USA-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.0392,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-15","TRTSDTM":"2019-12-17 16:17:31","TRT01SDTM":"2019-12-17 16:17:31","AP01SDTM":"2019-12-17 16:17:31","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5528,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.64829,"AVALU":"U/L","BASE2":3.1254,"BASE":5.96932,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.52289,"PCHG2":176.70999,"CHG":2.67896,"PCHG":44.87885,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-01-31 16:17:31","ADY":411,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-238","SUBJID":"id-238","SITEID":"USA-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.0392,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-15","TRTSDTM":"2019-12-17 16:17:31","TRT01SDTM":"2019-12-17 16:17:31","AP01SDTM":"2019-12-17 16:17:31","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5475,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.44752,"AVALU":"U/L","BASE2":3.1254,"BASE":5.96932,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":25.32213,"PCHG2":810.20518,"CHG":22.4782,"PCHG":376.56203,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-05-21 16:17:31","ADY":521,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-238","SUBJID":"id-238","SITEID":"USA-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.0392,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-15","TRTSDTM":"2019-12-17 16:17:31","TRT01SDTM":"2019-12-17 16:17:31","AP01SDTM":"2019-12-17 16:17:31","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5679,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.45078,"AVALU":"U/L","BASE2":3.1254,"BASE":5.96932,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.32538,"PCHG2":170.39065,"CHG":2.48146,"PCHG":41.57019,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-4","ADTM":"2021-08-23 16:17:31","ADY":615,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"4","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-238","SUBJID":"id-238","SITEID":"USA-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.0392,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-15","TRTSDTM":"2019-12-17 16:17:31","TRT01SDTM":"2019-12-17 16:17:31","AP01SDTM":"2019-12-17 16:17:31","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4568,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.37097,"AVALU":"mg/L","BASE2":10.37097,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-04-04 16:17:31","ADY":109,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-238","SUBJID":"id-238","SITEID":"USA-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.0392,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-15","TRTSDTM":"2019-12-17 16:17:31","TRT01SDTM":"2019-12-17 16:17:31","AP01SDTM":"2019-12-17 16:17:31","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2166,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.3574,"AVALU":"mg/L","BASE2":10.37097,"BASE":10.3574,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.01356,"PCHG2":-0.13077,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-11-04 16:17:31","ADY":323,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-238","SUBJID":"id-238","SITEID":"USA-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.0392,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-15","TRTSDTM":"2019-12-17 16:17:31","TRT01SDTM":"2019-12-17 16:17:31","AP01SDTM":"2019-12-17 16:17:31","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6171,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.90145,"AVALU":"mg/L","BASE2":10.37097,"BASE":10.3574,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.46951,"PCHG2":-14.16947,"CHG":-1.45595,"PCHG":-14.05709,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-11-21 16:17:31","ADY":340,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-238","SUBJID":"id-238","SITEID":"USA-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.0392,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-15","TRTSDTM":"2019-12-17 16:17:31","TRT01SDTM":"2019-12-17 16:17:31","AP01SDTM":"2019-12-17 16:17:31","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":595,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.60677,"AVALU":"mg/L","BASE2":10.37097,"BASE":10.3574,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.7642,"PCHG2":-7.36862,"CHG":-0.75063,"PCHG":-7.24733,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-12-22 16:17:31","ADY":371,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-238","SUBJID":"id-238","SITEID":"USA-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.0392,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-15","TRTSDTM":"2019-12-17 16:17:31","TRT01SDTM":"2019-12-17 16:17:31","AP01SDTM":"2019-12-17 16:17:31","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7738,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.32097,"AVALU":"mg/L","BASE2":10.37097,"BASE":10.3574,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.05,"PCHG2":-19.76669,"CHG":-2.03643,"PCHG":-19.66163,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-01-31 16:17:31","ADY":411,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-238","SUBJID":"id-238","SITEID":"USA-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.0392,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-15","TRTSDTM":"2019-12-17 16:17:31","TRT01SDTM":"2019-12-17 16:17:31","AP01SDTM":"2019-12-17 16:17:31","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6319,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.91598,"AVALU":"mg/L","BASE2":10.37097,"BASE":10.3574,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.45499,"PCHG2":-14.02946,"CHG":-1.44143,"PCHG":-13.91689,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-05-21 16:17:31","ADY":521,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-238","SUBJID":"id-238","SITEID":"USA-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.0392,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-15","TRTSDTM":"2019-12-17 16:17:31","TRT01SDTM":"2019-12-17 16:17:31","AP01SDTM":"2019-12-17 16:17:31","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6916,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.65768,"AVALU":"mg/L","BASE2":10.37097,"BASE":10.3574,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.71329,"PCHG2":-16.52007,"CHG":-1.69973,"PCHG":-16.41076,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-08-23 16:17:31","ADY":615,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-238","SUBJID":"id-238","SITEID":"USA-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.0392,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-15","TRTSDTM":"2019-12-17 16:17:31","TRT01SDTM":"2019-12-17 16:17:31","AP01SDTM":"2019-12-17 16:17:31","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7418,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76081,"AVALU":"g/L","BASE2":2.76081,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-04 16:17:31","ADY":109,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-238","SUBJID":"id-238","SITEID":"USA-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.0392,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-15","TRTSDTM":"2019-12-17 16:17:31","TRT01SDTM":"2019-12-17 16:17:31","AP01SDTM":"2019-12-17 16:17:31","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4109,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8482,"AVALU":"g/L","BASE2":2.76081,"BASE":2.8482,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.08739,"PCHG2":3.16555,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-04 16:17:31","ADY":323,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-238","SUBJID":"id-238","SITEID":"USA-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.0392,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-15","TRTSDTM":"2019-12-17 16:17:31","TRT01SDTM":"2019-12-17 16:17:31","AP01SDTM":"2019-12-17 16:17:31","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1136,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98677,"AVALU":"g/L","BASE2":2.76081,"BASE":2.8482,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.22596,"PCHG2":8.18471,"CHG":0.13857,"PCHG":4.86515,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-21 16:17:31","ADY":340,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-238","SUBJID":"id-238","SITEID":"USA-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.0392,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-15","TRTSDTM":"2019-12-17 16:17:31","TRT01SDTM":"2019-12-17 16:17:31","AP01SDTM":"2019-12-17 16:17:31","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7304,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86671,"AVALU":"g/L","BASE2":2.76081,"BASE":2.8482,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.1059,"PCHG2":3.83589,"CHG":0.01851,"PCHG":0.64977,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-22 16:17:31","ADY":371,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-238","SUBJID":"id-238","SITEID":"USA-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.0392,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-15","TRTSDTM":"2019-12-17 16:17:31","TRT01SDTM":"2019-12-17 16:17:31","AP01SDTM":"2019-12-17 16:17:31","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4593,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93209,"AVALU":"g/L","BASE2":2.76081,"BASE":2.8482,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.17129,"PCHG2":6.20419,"CHG":0.08389,"PCHG":2.94541,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-31 16:17:31","ADY":411,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-238","SUBJID":"id-238","SITEID":"USA-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.0392,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-15","TRTSDTM":"2019-12-17 16:17:31","TRT01SDTM":"2019-12-17 16:17:31","AP01SDTM":"2019-12-17 16:17:31","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2238,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99019,"AVALU":"g/L","BASE2":2.76081,"BASE":2.8482,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.22938,"PCHG2":8.30837,"CHG":0.14198,"PCHG":4.98502,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-21 16:17:31","ADY":521,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-238","SUBJID":"id-238","SITEID":"USA-11","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"UNKNOWN","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.0392,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-12-15","TRTSDTM":"2019-12-17 16:17:31","TRT01SDTM":"2019-12-17 16:17:31","AP01SDTM":"2019-12-17 16:17:31","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5045,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97902,"AVALU":"g/L","BASE2":2.76081,"BASE":2.8482,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.21821,"PCHG2":7.90379,"CHG":0.13081,"PCHG":4.59285,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-23 16:17:31","ADY":615,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-32","SUBJID":"id-32","SITEID":"USA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.45456,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-13 22:38:04","TRTEDTM":"2023-03-14 16:38:04","TRT01SDTM":"2020-03-13 22:38:04","TRT01EDTM":"2022-03-14 10:38:04","TRT02SDTM":"2022-03-14 10:38:04","TRT02EDTM":"2023-03-14 16:38:04","AP01SDTM":"2020-03-13 22:38:04","AP01EDTM":"2022-03-14 10:38:04","AP02SDTM":"2022-03-14 10:38:04","AP02EDTM":"2023-03-14 16:38:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-14","EOSDY":1096,"LSTALVDT":"2023-04-05","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4097,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.02132,"AVALU":"U/L","BASE2":18.02132,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-03 22:38:04","ADY":112,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-32","SUBJID":"id-32","SITEID":"USA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.45456,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-13 22:38:04","TRTEDTM":"2023-03-14 16:38:04","TRT01SDTM":"2020-03-13 22:38:04","TRT01EDTM":"2022-03-14 10:38:04","TRT02SDTM":"2022-03-14 10:38:04","TRT02EDTM":"2023-03-14 16:38:04","AP01SDTM":"2020-03-13 22:38:04","AP01EDTM":"2022-03-14 10:38:04","AP02SDTM":"2022-03-14 10:38:04","AP02EDTM":"2023-03-14 16:38:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-14","EOSDY":1096,"LSTALVDT":"2023-04-05","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3316,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.2947,"AVALU":"U/L","BASE2":18.02132,"BASE":21.2947,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":3.27338,"PCHG2":18.16393,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-25 22:38:04","ADY":196,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-32","SUBJID":"id-32","SITEID":"USA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.45456,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-13 22:38:04","TRTEDTM":"2023-03-14 16:38:04","TRT01SDTM":"2020-03-13 22:38:04","TRT01EDTM":"2022-03-14 10:38:04","TRT02SDTM":"2022-03-14 10:38:04","TRT02EDTM":"2023-03-14 16:38:04","AP01SDTM":"2020-03-13 22:38:04","AP01EDTM":"2022-03-14 10:38:04","AP02SDTM":"2022-03-14 10:38:04","AP02EDTM":"2023-03-14 16:38:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-14","EOSDY":1096,"LSTALVDT":"2023-04-05","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4514,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.10053,"AVALU":"U/L","BASE2":18.02132,"BASE":21.2947,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":9.07922,"PCHG2":50.38041,"CHG":5.80584,"PCHG":27.26423,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-04 22:38:04","ADY":236,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-32","SUBJID":"id-32","SITEID":"USA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.45456,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-13 22:38:04","TRTEDTM":"2023-03-14 16:38:04","TRT01SDTM":"2020-03-13 22:38:04","TRT01EDTM":"2022-03-14 10:38:04","TRT02SDTM":"2022-03-14 10:38:04","TRT02EDTM":"2023-03-14 16:38:04","AP01SDTM":"2020-03-13 22:38:04","AP01EDTM":"2022-03-14 10:38:04","AP02SDTM":"2022-03-14 10:38:04","AP02EDTM":"2023-03-14 16:38:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-14","EOSDY":1096,"LSTALVDT":"2023-04-05","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4350,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.54705,"AVALU":"U/L","BASE2":18.02132,"BASE":21.2947,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.52573,"PCHG2":58.40712,"CHG":7.25235,"PCHG":34.05709,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-20 22:38:04","ADY":433,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-32","SUBJID":"id-32","SITEID":"USA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.45456,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-13 22:38:04","TRTEDTM":"2023-03-14 16:38:04","TRT01SDTM":"2020-03-13 22:38:04","TRT01EDTM":"2022-03-14 10:38:04","TRT02SDTM":"2022-03-14 10:38:04","TRT02EDTM":"2023-03-14 16:38:04","AP01SDTM":"2020-03-13 22:38:04","AP01EDTM":"2022-03-14 10:38:04","AP02SDTM":"2022-03-14 10:38:04","AP02EDTM":"2023-03-14 16:38:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-14","EOSDY":1096,"LSTALVDT":"2023-04-05","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3707,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.48106,"AVALU":"U/L","BASE2":18.02132,"BASE":21.2947,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.45974,"PCHG2":80.23685,"CHG":11.18636,"PCHG":52.53119,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-25 22:38:04","ADY":895,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-32","SUBJID":"id-32","SITEID":"USA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.45456,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-13 22:38:04","TRTEDTM":"2023-03-14 16:38:04","TRT01SDTM":"2020-03-13 22:38:04","TRT01EDTM":"2022-03-14 10:38:04","TRT02SDTM":"2022-03-14 10:38:04","TRT02EDTM":"2023-03-14 16:38:04","AP01SDTM":"2020-03-13 22:38:04","AP01EDTM":"2022-03-14 10:38:04","AP02SDTM":"2022-03-14 10:38:04","AP02EDTM":"2023-03-14 16:38:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-14","EOSDY":1096,"LSTALVDT":"2023-04-05","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6936,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.73284,"AVALU":"U/L","BASE2":18.02132,"BASE":21.2947,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-16.28848,"PCHG2":-90.38449,"CHG":-19.56186,"PCHG":-91.86257,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2022-09-21 22:38:04","ADY":922,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-32","SUBJID":"id-32","SITEID":"USA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.45456,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-13 22:38:04","TRTEDTM":"2023-03-14 16:38:04","TRT01SDTM":"2020-03-13 22:38:04","TRT01EDTM":"2022-03-14 10:38:04","TRT02SDTM":"2022-03-14 10:38:04","TRT02EDTM":"2023-03-14 16:38:04","AP01SDTM":"2020-03-13 22:38:04","AP01EDTM":"2022-03-14 10:38:04","AP02SDTM":"2022-03-14 10:38:04","AP02EDTM":"2023-03-14 16:38:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-14","EOSDY":1096,"LSTALVDT":"2023-04-05","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3529,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.57093,"AVALU":"U/L","BASE2":18.02132,"BASE":21.2947,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.45038,"PCHG2":-46.89104,"CHG":-11.72376,"PCHG":-55.05485,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-10 22:38:04","ADY":1033,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-32","SUBJID":"id-32","SITEID":"USA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.45456,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-13 22:38:04","TRTEDTM":"2023-03-14 16:38:04","TRT01SDTM":"2020-03-13 22:38:04","TRT01EDTM":"2022-03-14 10:38:04","TRT02SDTM":"2022-03-14 10:38:04","TRT02EDTM":"2023-03-14 16:38:04","AP01SDTM":"2020-03-13 22:38:04","AP01EDTM":"2022-03-14 10:38:04","AP02SDTM":"2022-03-14 10:38:04","AP02EDTM":"2023-03-14 16:38:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-14","EOSDY":1096,"LSTALVDT":"2023-04-05","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3460,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.37781,"AVALU":"mg/L","BASE2":10.37781,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-07-03 22:38:04","ADY":112,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-32","SUBJID":"id-32","SITEID":"USA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.45456,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-13 22:38:04","TRTEDTM":"2023-03-14 16:38:04","TRT01SDTM":"2020-03-13 22:38:04","TRT01EDTM":"2022-03-14 10:38:04","TRT02SDTM":"2022-03-14 10:38:04","TRT02EDTM":"2023-03-14 16:38:04","AP01SDTM":"2020-03-13 22:38:04","AP01EDTM":"2022-03-14 10:38:04","AP02SDTM":"2022-03-14 10:38:04","AP02EDTM":"2023-03-14 16:38:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-14","EOSDY":1096,"LSTALVDT":"2023-04-05","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8078,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.03455,"AVALU":"mg/L","BASE2":10.37781,"BASE":8.03455,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.34327,"PCHG2":-22.57957,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-25 22:38:04","ADY":196,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-32","SUBJID":"id-32","SITEID":"USA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.45456,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-13 22:38:04","TRTEDTM":"2023-03-14 16:38:04","TRT01SDTM":"2020-03-13 22:38:04","TRT01EDTM":"2022-03-14 10:38:04","TRT02SDTM":"2022-03-14 10:38:04","TRT02EDTM":"2023-03-14 16:38:04","AP01SDTM":"2020-03-13 22:38:04","AP01EDTM":"2022-03-14 10:38:04","AP02SDTM":"2022-03-14 10:38:04","AP02EDTM":"2023-03-14 16:38:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-14","EOSDY":1096,"LSTALVDT":"2023-04-05","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3741,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.69346,"AVALU":"mg/L","BASE2":10.37781,"BASE":8.03455,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.68435,"PCHG2":-6.59436,"CHG":1.65892,"PCHG":20.64729,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-04 22:38:04","ADY":236,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-32","SUBJID":"id-32","SITEID":"USA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.45456,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-13 22:38:04","TRTEDTM":"2023-03-14 16:38:04","TRT01SDTM":"2020-03-13 22:38:04","TRT01EDTM":"2022-03-14 10:38:04","TRT02SDTM":"2022-03-14 10:38:04","TRT02EDTM":"2023-03-14 16:38:04","AP01SDTM":"2020-03-13 22:38:04","AP01EDTM":"2022-03-14 10:38:04","AP02SDTM":"2022-03-14 10:38:04","AP02EDTM":"2023-03-14 16:38:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-14","EOSDY":1096,"LSTALVDT":"2023-04-05","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2674,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.68931,"AVALU":"mg/L","BASE2":10.37781,"BASE":8.03455,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.31149,"PCHG2":3.00153,"CHG":2.65476,"PCHG":33.0418,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-05-20 22:38:04","ADY":433,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-32","SUBJID":"id-32","SITEID":"USA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.45456,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-13 22:38:04","TRTEDTM":"2023-03-14 16:38:04","TRT01SDTM":"2020-03-13 22:38:04","TRT01EDTM":"2022-03-14 10:38:04","TRT02SDTM":"2022-03-14 10:38:04","TRT02EDTM":"2023-03-14 16:38:04","AP01SDTM":"2020-03-13 22:38:04","AP01EDTM":"2022-03-14 10:38:04","AP02SDTM":"2022-03-14 10:38:04","AP02EDTM":"2023-03-14 16:38:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-14","EOSDY":1096,"LSTALVDT":"2023-04-05","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3952,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.8299,"AVALU":"mg/L","BASE2":10.37781,"BASE":8.03455,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.54792,"PCHG2":-14.91563,"CHG":0.79535,"PCHG":9.89913,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-25 22:38:04","ADY":895,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-32","SUBJID":"id-32","SITEID":"USA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.45456,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-13 22:38:04","TRTEDTM":"2023-03-14 16:38:04","TRT01SDTM":"2020-03-13 22:38:04","TRT01EDTM":"2022-03-14 10:38:04","TRT02SDTM":"2022-03-14 10:38:04","TRT02EDTM":"2023-03-14 16:38:04","AP01SDTM":"2020-03-13 22:38:04","AP01EDTM":"2022-03-14 10:38:04","AP02SDTM":"2022-03-14 10:38:04","AP02EDTM":"2023-03-14 16:38:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-14","EOSDY":1096,"LSTALVDT":"2023-04-05","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2404,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.40168,"AVALU":"mg/L","BASE2":10.37781,"BASE":8.03455,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02386,"PCHG2":0.22995,"CHG":2.36713,"PCHG":29.46189,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-09-21 22:38:04","ADY":922,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-32","SUBJID":"id-32","SITEID":"USA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.45456,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-13 22:38:04","TRTEDTM":"2023-03-14 16:38:04","TRT01SDTM":"2020-03-13 22:38:04","TRT01EDTM":"2022-03-14 10:38:04","TRT02SDTM":"2022-03-14 10:38:04","TRT02EDTM":"2023-03-14 16:38:04","AP01SDTM":"2020-03-13 22:38:04","AP01EDTM":"2022-03-14 10:38:04","AP02SDTM":"2022-03-14 10:38:04","AP02EDTM":"2023-03-14 16:38:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-14","EOSDY":1096,"LSTALVDT":"2023-04-05","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6913,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.54816,"AVALU":"mg/L","BASE2":10.37781,"BASE":8.03455,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.82965,"PCHG2":-27.26637,"CHG":-0.48639,"PCHG":-6.05369,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2023-01-10 22:38:04","ADY":1033,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-32","SUBJID":"id-32","SITEID":"USA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.45456,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-13 22:38:04","TRTEDTM":"2023-03-14 16:38:04","TRT01SDTM":"2020-03-13 22:38:04","TRT01EDTM":"2022-03-14 10:38:04","TRT02SDTM":"2022-03-14 10:38:04","TRT02EDTM":"2023-03-14 16:38:04","AP01SDTM":"2020-03-13 22:38:04","AP01EDTM":"2022-03-14 10:38:04","AP02SDTM":"2022-03-14 10:38:04","AP02EDTM":"2023-03-14 16:38:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-14","EOSDY":1096,"LSTALVDT":"2023-04-05","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5847,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88906,"AVALU":"g/L","BASE2":2.88906,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-03 22:38:04","ADY":112,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-32","SUBJID":"id-32","SITEID":"USA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.45456,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-13 22:38:04","TRTEDTM":"2023-03-14 16:38:04","TRT01SDTM":"2020-03-13 22:38:04","TRT01EDTM":"2022-03-14 10:38:04","TRT02SDTM":"2022-03-14 10:38:04","TRT02EDTM":"2023-03-14 16:38:04","AP01SDTM":"2020-03-13 22:38:04","AP01EDTM":"2022-03-14 10:38:04","AP02SDTM":"2022-03-14 10:38:04","AP02EDTM":"2023-03-14 16:38:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-14","EOSDY":1096,"LSTALVDT":"2023-04-05","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5666,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89727,"AVALU":"g/L","BASE2":2.88906,"BASE":2.89727,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.00821,"PCHG2":0.28422,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-25 22:38:04","ADY":196,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-32","SUBJID":"id-32","SITEID":"USA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.45456,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-13 22:38:04","TRTEDTM":"2023-03-14 16:38:04","TRT01SDTM":"2020-03-13 22:38:04","TRT01EDTM":"2022-03-14 10:38:04","TRT02SDTM":"2022-03-14 10:38:04","TRT02EDTM":"2023-03-14 16:38:04","AP01SDTM":"2020-03-13 22:38:04","AP01EDTM":"2022-03-14 10:38:04","AP02SDTM":"2022-03-14 10:38:04","AP02EDTM":"2023-03-14 16:38:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-14","EOSDY":1096,"LSTALVDT":"2023-04-05","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7960,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87427,"AVALU":"g/L","BASE2":2.88906,"BASE":2.89727,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01479,"PCHG2":-0.51188,"CHG":-0.023,"PCHG":-0.79384,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-04 22:38:04","ADY":236,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-32","SUBJID":"id-32","SITEID":"USA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.45456,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-13 22:38:04","TRTEDTM":"2023-03-14 16:38:04","TRT01SDTM":"2020-03-13 22:38:04","TRT01EDTM":"2022-03-14 10:38:04","TRT02SDTM":"2022-03-14 10:38:04","TRT02EDTM":"2023-03-14 16:38:04","AP01SDTM":"2020-03-13 22:38:04","AP01EDTM":"2022-03-14 10:38:04","AP02SDTM":"2022-03-14 10:38:04","AP02EDTM":"2023-03-14 16:38:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-14","EOSDY":1096,"LSTALVDT":"2023-04-05","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3027,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88064,"AVALU":"g/L","BASE2":2.88906,"BASE":2.89727,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00842,"PCHG2":-0.29147,"CHG":-0.01663,"PCHG":-0.57406,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-20 22:38:04","ADY":433,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-32","SUBJID":"id-32","SITEID":"USA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.45456,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-13 22:38:04","TRTEDTM":"2023-03-14 16:38:04","TRT01SDTM":"2020-03-13 22:38:04","TRT01EDTM":"2022-03-14 10:38:04","TRT02SDTM":"2022-03-14 10:38:04","TRT02EDTM":"2023-03-14 16:38:04","AP01SDTM":"2020-03-13 22:38:04","AP01EDTM":"2022-03-14 10:38:04","AP02SDTM":"2022-03-14 10:38:04","AP02EDTM":"2023-03-14 16:38:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-14","EOSDY":1096,"LSTALVDT":"2023-04-05","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4171,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91047,"AVALU":"g/L","BASE2":2.88906,"BASE":2.89727,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02141,"PCHG2":0.74091,"CHG":0.01319,"PCHG":0.4554,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-25 22:38:04","ADY":895,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-32","SUBJID":"id-32","SITEID":"USA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.45456,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-13 22:38:04","TRTEDTM":"2023-03-14 16:38:04","TRT01SDTM":"2020-03-13 22:38:04","TRT01EDTM":"2022-03-14 10:38:04","TRT02SDTM":"2022-03-14 10:38:04","TRT02EDTM":"2023-03-14 16:38:04","AP01SDTM":"2020-03-13 22:38:04","AP01EDTM":"2022-03-14 10:38:04","AP02SDTM":"2022-03-14 10:38:04","AP02EDTM":"2023-03-14 16:38:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-14","EOSDY":1096,"LSTALVDT":"2023-04-05","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7787,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93727,"AVALU":"g/L","BASE2":2.88906,"BASE":2.89727,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04821,"PCHG2":1.6687,"CHG":0.04,"PCHG":1.38056,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-21 22:38:04","ADY":922,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-32","SUBJID":"id-32","SITEID":"USA-11","AGE":24,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":8.45456,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-03-09","TRTSDTM":"2020-03-13 22:38:04","TRTEDTM":"2023-03-14 16:38:04","TRT01SDTM":"2020-03-13 22:38:04","TRT01EDTM":"2022-03-14 10:38:04","TRT02SDTM":"2022-03-14 10:38:04","TRT02EDTM":"2023-03-14 16:38:04","AP01SDTM":"2020-03-13 22:38:04","AP01EDTM":"2022-03-14 10:38:04","AP02SDTM":"2022-03-14 10:38:04","AP02EDTM":"2023-03-14 16:38:04","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-14","EOSDY":1096,"LSTALVDT":"2023-04-05","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2435,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99504,"AVALU":"g/L","BASE2":2.88906,"BASE":2.89727,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10598,"PCHG2":3.66839,"CHG":0.09777,"PCHG":3.37459,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-10 22:38:04","ADY":1033,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-339","SUBJID":"id-339","SITEID":"USA-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":17.21213,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-17","TRTSDTM":"2019-10-19 19:45:27","TRTEDTM":"2022-02-19 12:30:11","TRT01SDTM":"2019-10-19 19:45:27","TRT01EDTM":"2021-02-19 06:30:11","TRT02SDTM":"2021-02-19 06:30:11","TRT02EDTM":"2022-02-19 12:30:11","AP01SDTM":"2019-10-19 19:45:27","AP01EDTM":"2021-02-19 06:30:11","AP02SDTM":"2021-02-19 06:30:11","AP02EDTM":"2022-02-19 12:30:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":854,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":878,"ADTHAUT":"No","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6970,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.62366,"AVALU":"U/L","BASE2":17.62366,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-13 19:45:27","ADY":268,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-339","SUBJID":"id-339","SITEID":"USA-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":17.21213,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-17","TRTSDTM":"2019-10-19 19:45:27","TRTEDTM":"2022-02-19 12:30:11","TRT01SDTM":"2019-10-19 19:45:27","TRT01EDTM":"2021-02-19 06:30:11","TRT02SDTM":"2021-02-19 06:30:11","TRT02EDTM":"2022-02-19 12:30:11","AP01SDTM":"2019-10-19 19:45:27","AP01EDTM":"2021-02-19 06:30:11","AP02SDTM":"2021-02-19 06:30:11","AP02EDTM":"2022-02-19 12:30:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":854,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":878,"ADTHAUT":"No","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1977,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.72267,"AVALU":"U/L","BASE2":17.62366,"BASE":9.72267,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-7.90099,"PCHG2":-44.83172,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-03 19:45:27","ADY":289,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-339","SUBJID":"id-339","SITEID":"USA-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":17.21213,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-17","TRTSDTM":"2019-10-19 19:45:27","TRTEDTM":"2022-02-19 12:30:11","TRT01SDTM":"2019-10-19 19:45:27","TRT01EDTM":"2021-02-19 06:30:11","TRT02SDTM":"2021-02-19 06:30:11","TRT02EDTM":"2022-02-19 12:30:11","AP01SDTM":"2019-10-19 19:45:27","AP01EDTM":"2021-02-19 06:30:11","AP02SDTM":"2021-02-19 06:30:11","AP02EDTM":"2022-02-19 12:30:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":854,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":878,"ADTHAUT":"No","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2443,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.98654,"AVALU":"U/L","BASE2":17.62366,"BASE":9.72267,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.36288,"PCHG2":75.82356,"CHG":21.26387,"PCHG":218.70406,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-20 19:45:27","ADY":306,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-339","SUBJID":"id-339","SITEID":"USA-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":17.21213,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-17","TRTSDTM":"2019-10-19 19:45:27","TRTEDTM":"2022-02-19 12:30:11","TRT01SDTM":"2019-10-19 19:45:27","TRT01EDTM":"2021-02-19 06:30:11","TRT02SDTM":"2021-02-19 06:30:11","TRT02EDTM":"2022-02-19 12:30:11","AP01SDTM":"2019-10-19 19:45:27","AP01EDTM":"2021-02-19 06:30:11","AP02SDTM":"2021-02-19 06:30:11","AP02EDTM":"2022-02-19 12:30:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":854,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":878,"ADTHAUT":"No","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7450,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.19669,"AVALU":"U/L","BASE2":17.62366,"BASE":9.72267,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.57303,"PCHG2":77.01597,"CHG":21.47402,"PCHG":220.86547,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-18 19:45:27","ADY":365,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-339","SUBJID":"id-339","SITEID":"USA-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":17.21213,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-17","TRTSDTM":"2019-10-19 19:45:27","TRTEDTM":"2022-02-19 12:30:11","TRT01SDTM":"2019-10-19 19:45:27","TRT01EDTM":"2021-02-19 06:30:11","TRT02SDTM":"2021-02-19 06:30:11","TRT02EDTM":"2022-02-19 12:30:11","AP01SDTM":"2019-10-19 19:45:27","AP01EDTM":"2021-02-19 06:30:11","AP02SDTM":"2021-02-19 06:30:11","AP02EDTM":"2022-02-19 12:30:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":854,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":878,"ADTHAUT":"No","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2117,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.55349,"AVALU":"U/L","BASE2":17.62366,"BASE":9.72267,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.07017,"PCHG2":-68.48845,"CHG":-4.16918,"PCHG":-42.88103,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-04-06 19:45:27","ADY":535,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-339","SUBJID":"id-339","SITEID":"USA-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":17.21213,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-17","TRTSDTM":"2019-10-19 19:45:27","TRTEDTM":"2022-02-19 12:30:11","TRT01SDTM":"2019-10-19 19:45:27","TRT01EDTM":"2021-02-19 06:30:11","TRT02SDTM":"2021-02-19 06:30:11","TRT02EDTM":"2022-02-19 12:30:11","AP01SDTM":"2019-10-19 19:45:27","AP01EDTM":"2021-02-19 06:30:11","AP02SDTM":"2021-02-19 06:30:11","AP02EDTM":"2022-02-19 12:30:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":854,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":878,"ADTHAUT":"No","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7293,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":41.30358,"AVALU":"U/L","BASE2":17.62366,"BASE":9.72267,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":23.67993,"PCHG2":134.36442,"CHG":31.58091,"PCHG":324.81732,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-06 19:45:27","ADY":565,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-339","SUBJID":"id-339","SITEID":"USA-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":17.21213,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-17","TRTSDTM":"2019-10-19 19:45:27","TRTEDTM":"2022-02-19 12:30:11","TRT01SDTM":"2019-10-19 19:45:27","TRT01EDTM":"2021-02-19 06:30:11","TRT02SDTM":"2021-02-19 06:30:11","TRT02EDTM":"2022-02-19 12:30:11","AP01SDTM":"2019-10-19 19:45:27","AP01EDTM":"2021-02-19 06:30:11","AP02SDTM":"2021-02-19 06:30:11","AP02EDTM":"2022-02-19 12:30:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":854,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":878,"ADTHAUT":"No","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6047,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.42738,"AVALU":"U/L","BASE2":17.62366,"BASE":9.72267,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.80372,"PCHG2":27.25725,"CHG":12.70471,"PCHG":130.67104,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-22 19:45:27","ADY":581,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-339","SUBJID":"id-339","SITEID":"USA-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":17.21213,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-17","TRTSDTM":"2019-10-19 19:45:27","TRTEDTM":"2022-02-19 12:30:11","TRT01SDTM":"2019-10-19 19:45:27","TRT01EDTM":"2021-02-19 06:30:11","TRT02SDTM":"2021-02-19 06:30:11","TRT02EDTM":"2022-02-19 12:30:11","AP01SDTM":"2019-10-19 19:45:27","AP01EDTM":"2021-02-19 06:30:11","AP02SDTM":"2021-02-19 06:30:11","AP02EDTM":"2022-02-19 12:30:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":854,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":878,"ADTHAUT":"No","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6828,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.88379,"AVALU":"mg/L","BASE2":8.88379,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-13 19:45:27","ADY":268,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-339","SUBJID":"id-339","SITEID":"USA-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":17.21213,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-17","TRTSDTM":"2019-10-19 19:45:27","TRTEDTM":"2022-02-19 12:30:11","TRT01SDTM":"2019-10-19 19:45:27","TRT01EDTM":"2021-02-19 06:30:11","TRT02SDTM":"2021-02-19 06:30:11","TRT02EDTM":"2022-02-19 12:30:11","AP01SDTM":"2019-10-19 19:45:27","AP01EDTM":"2021-02-19 06:30:11","AP02SDTM":"2021-02-19 06:30:11","AP02EDTM":"2022-02-19 12:30:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":854,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":878,"ADTHAUT":"No","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6998,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.61457,"AVALU":"mg/L","BASE2":8.88379,"BASE":8.61457,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.26922,"PCHG2":-3.03042,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-03 19:45:27","ADY":289,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-339","SUBJID":"id-339","SITEID":"USA-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":17.21213,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-17","TRTSDTM":"2019-10-19 19:45:27","TRTEDTM":"2022-02-19 12:30:11","TRT01SDTM":"2019-10-19 19:45:27","TRT01EDTM":"2021-02-19 06:30:11","TRT02SDTM":"2021-02-19 06:30:11","TRT02EDTM":"2022-02-19 12:30:11","AP01SDTM":"2019-10-19 19:45:27","AP01EDTM":"2021-02-19 06:30:11","AP02SDTM":"2021-02-19 06:30:11","AP02EDTM":"2022-02-19 12:30:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":854,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":878,"ADTHAUT":"No","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3698,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.92754,"AVALU":"mg/L","BASE2":8.88379,"BASE":8.61457,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.04375,"PCHG2":11.74898,"CHG":1.31297,"PCHG":15.24127,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-20 19:45:27","ADY":306,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-339","SUBJID":"id-339","SITEID":"USA-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":17.21213,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-17","TRTSDTM":"2019-10-19 19:45:27","TRTEDTM":"2022-02-19 12:30:11","TRT01SDTM":"2019-10-19 19:45:27","TRT01EDTM":"2021-02-19 06:30:11","TRT02SDTM":"2021-02-19 06:30:11","TRT02EDTM":"2022-02-19 12:30:11","AP01SDTM":"2019-10-19 19:45:27","AP01EDTM":"2021-02-19 06:30:11","AP02SDTM":"2021-02-19 06:30:11","AP02EDTM":"2022-02-19 12:30:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":854,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":878,"ADTHAUT":"No","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5128,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.87103,"AVALU":"mg/L","BASE2":8.88379,"BASE":8.61457,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.98724,"PCHG2":11.11283,"CHG":1.25646,"PCHG":14.58524,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-18 19:45:27","ADY":365,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-339","SUBJID":"id-339","SITEID":"USA-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":17.21213,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-17","TRTSDTM":"2019-10-19 19:45:27","TRTEDTM":"2022-02-19 12:30:11","TRT01SDTM":"2019-10-19 19:45:27","TRT01EDTM":"2021-02-19 06:30:11","TRT02SDTM":"2021-02-19 06:30:11","TRT02EDTM":"2022-02-19 12:30:11","AP01SDTM":"2019-10-19 19:45:27","AP01EDTM":"2021-02-19 06:30:11","AP02SDTM":"2021-02-19 06:30:11","AP02EDTM":"2022-02-19 12:30:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":854,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":878,"ADTHAUT":"No","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2731,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.36194,"AVALU":"mg/L","BASE2":8.88379,"BASE":8.61457,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.47815,"PCHG2":5.38231,"CHG":0.74737,"PCHG":8.67563,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-06 19:45:27","ADY":535,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-339","SUBJID":"id-339","SITEID":"USA-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":17.21213,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-17","TRTSDTM":"2019-10-19 19:45:27","TRTEDTM":"2022-02-19 12:30:11","TRT01SDTM":"2019-10-19 19:45:27","TRT01EDTM":"2021-02-19 06:30:11","TRT02SDTM":"2021-02-19 06:30:11","TRT02EDTM":"2022-02-19 12:30:11","AP01SDTM":"2019-10-19 19:45:27","AP01EDTM":"2021-02-19 06:30:11","AP02SDTM":"2021-02-19 06:30:11","AP02EDTM":"2022-02-19 12:30:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":854,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":878,"ADTHAUT":"No","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7995,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.83289,"AVALU":"mg/L","BASE2":8.88379,"BASE":8.61457,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.9491,"PCHG2":21.93997,"CHG":2.21832,"PCHG":25.75074,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-05-06 19:45:27","ADY":565,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-339","SUBJID":"id-339","SITEID":"USA-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":17.21213,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-17","TRTSDTM":"2019-10-19 19:45:27","TRTEDTM":"2022-02-19 12:30:11","TRT01SDTM":"2019-10-19 19:45:27","TRT01EDTM":"2021-02-19 06:30:11","TRT02SDTM":"2021-02-19 06:30:11","TRT02EDTM":"2022-02-19 12:30:11","AP01SDTM":"2019-10-19 19:45:27","AP01EDTM":"2021-02-19 06:30:11","AP02SDTM":"2021-02-19 06:30:11","AP02EDTM":"2022-02-19 12:30:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":854,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":878,"ADTHAUT":"No","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":161,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.38754,"AVALU":"mg/L","BASE2":8.88379,"BASE":8.61457,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.50375,"PCHG2":5.67045,"CHG":0.77297,"PCHG":8.97278,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-22 19:45:27","ADY":581,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-339","SUBJID":"id-339","SITEID":"USA-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":17.21213,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-17","TRTSDTM":"2019-10-19 19:45:27","TRTEDTM":"2022-02-19 12:30:11","TRT01SDTM":"2019-10-19 19:45:27","TRT01EDTM":"2021-02-19 06:30:11","TRT02SDTM":"2021-02-19 06:30:11","TRT02EDTM":"2022-02-19 12:30:11","AP01SDTM":"2019-10-19 19:45:27","AP01EDTM":"2021-02-19 06:30:11","AP02SDTM":"2021-02-19 06:30:11","AP02EDTM":"2022-02-19 12:30:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":854,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":878,"ADTHAUT":"No","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8094,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.13946,"AVALU":"g/L","BASE2":3.13946,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-07-13 19:45:27","ADY":268,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-339","SUBJID":"id-339","SITEID":"USA-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":17.21213,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-17","TRTSDTM":"2019-10-19 19:45:27","TRTEDTM":"2022-02-19 12:30:11","TRT01SDTM":"2019-10-19 19:45:27","TRT01EDTM":"2021-02-19 06:30:11","TRT02SDTM":"2021-02-19 06:30:11","TRT02EDTM":"2022-02-19 12:30:11","AP01SDTM":"2019-10-19 19:45:27","AP01EDTM":"2021-02-19 06:30:11","AP02SDTM":"2021-02-19 06:30:11","AP02EDTM":"2022-02-19 12:30:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":854,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":878,"ADTHAUT":"No","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5207,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89228,"AVALU":"g/L","BASE2":3.13946,"BASE":2.89228,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.24719,"PCHG2":-7.87351,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-03 19:45:27","ADY":289,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-339","SUBJID":"id-339","SITEID":"USA-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":17.21213,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-17","TRTSDTM":"2019-10-19 19:45:27","TRTEDTM":"2022-02-19 12:30:11","TRT01SDTM":"2019-10-19 19:45:27","TRT01EDTM":"2021-02-19 06:30:11","TRT02SDTM":"2021-02-19 06:30:11","TRT02EDTM":"2022-02-19 12:30:11","AP01SDTM":"2019-10-19 19:45:27","AP01EDTM":"2021-02-19 06:30:11","AP02SDTM":"2021-02-19 06:30:11","AP02EDTM":"2022-02-19 12:30:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":854,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":878,"ADTHAUT":"No","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3677,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95589,"AVALU":"g/L","BASE2":3.13946,"BASE":2.89228,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18357,"PCHG2":-5.84726,"CHG":0.06361,"PCHG":2.19941,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-20 19:45:27","ADY":306,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-339","SUBJID":"id-339","SITEID":"USA-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":17.21213,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-17","TRTSDTM":"2019-10-19 19:45:27","TRTEDTM":"2022-02-19 12:30:11","TRT01SDTM":"2019-10-19 19:45:27","TRT01EDTM":"2021-02-19 06:30:11","TRT02SDTM":"2021-02-19 06:30:11","TRT02EDTM":"2022-02-19 12:30:11","AP01SDTM":"2019-10-19 19:45:27","AP01EDTM":"2021-02-19 06:30:11","AP02SDTM":"2021-02-19 06:30:11","AP02EDTM":"2022-02-19 12:30:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":854,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":878,"ADTHAUT":"No","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3293,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95567,"AVALU":"g/L","BASE2":3.13946,"BASE":2.89228,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.18379,"PCHG2":-5.85424,"CHG":0.06339,"PCHG":2.19184,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-18 19:45:27","ADY":365,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-339","SUBJID":"id-339","SITEID":"USA-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":17.21213,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-17","TRTSDTM":"2019-10-19 19:45:27","TRTEDTM":"2022-02-19 12:30:11","TRT01SDTM":"2019-10-19 19:45:27","TRT01EDTM":"2021-02-19 06:30:11","TRT02SDTM":"2021-02-19 06:30:11","TRT02EDTM":"2022-02-19 12:30:11","AP01SDTM":"2019-10-19 19:45:27","AP01EDTM":"2021-02-19 06:30:11","AP02SDTM":"2021-02-19 06:30:11","AP02EDTM":"2022-02-19 12:30:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":854,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":878,"ADTHAUT":"No","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8081,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89754,"AVALU":"g/L","BASE2":3.13946,"BASE":2.89228,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.24192,"PCHG2":-7.70587,"CHG":0.00526,"PCHG":0.18196,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-06 19:45:27","ADY":535,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-339","SUBJID":"id-339","SITEID":"USA-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":17.21213,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-17","TRTSDTM":"2019-10-19 19:45:27","TRTEDTM":"2022-02-19 12:30:11","TRT01SDTM":"2019-10-19 19:45:27","TRT01EDTM":"2021-02-19 06:30:11","TRT02SDTM":"2021-02-19 06:30:11","TRT02EDTM":"2022-02-19 12:30:11","AP01SDTM":"2019-10-19 19:45:27","AP01EDTM":"2021-02-19 06:30:11","AP02SDTM":"2021-02-19 06:30:11","AP02EDTM":"2022-02-19 12:30:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":854,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":878,"ADTHAUT":"No","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3026,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75053,"AVALU":"g/L","BASE2":3.13946,"BASE":2.89228,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.38893,"PCHG2":-12.38843,"CHG":-0.14174,"PCHG":-4.90079,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-06 19:45:27","ADY":565,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-339","SUBJID":"id-339","SITEID":"USA-11","AGE":39,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":17.21213,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-17","TRTSDTM":"2019-10-19 19:45:27","TRTEDTM":"2022-02-19 12:30:11","TRT01SDTM":"2019-10-19 19:45:27","TRT01EDTM":"2021-02-19 06:30:11","TRT02SDTM":"2021-02-19 06:30:11","TRT02EDTM":"2022-02-19 12:30:11","AP01SDTM":"2019-10-19 19:45:27","AP01EDTM":"2021-02-19 06:30:11","AP02SDTM":"2021-02-19 06:30:11","AP02EDTM":"2022-02-19 12:30:11","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-19","EOSDY":854,"DCSREAS":"DEATH","DTHDT":"2022-03-16","DTHCAUS":"UNKNOWN","DTHCAT":"OTHER","LDDTHELD":25,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-16","DTHADY":878,"ADTHAUT":"No","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4564,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90663,"AVALU":"g/L","BASE2":3.13946,"BASE":2.89228,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.23283,"PCHG2":-7.41613,"CHG":0.01436,"PCHG":0.49646,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-22 19:45:27","ADY":581,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-365","SUBJID":"id-365","SITEID":"USA-11","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90915,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-09","TRTSDTM":"2019-06-09 18:23:33","TRTEDTM":"2022-02-14 01:28:19","TRT01SDTM":"2019-06-09 18:23:33","TRT01EDTM":"2021-02-13 19:28:19","TRT02SDTM":"2021-02-13 19:28:19","TRT02EDTM":"2022-02-14 01:28:19","AP01SDTM":"2019-06-09 18:23:33","AP01EDTM":"2021-02-13 19:28:19","AP02SDTM":"2021-02-13 19:28:19","AP02EDTM":"2022-02-14 01:28:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":981,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":1002,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5562,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.70637,"AVALU":"U/L","BASE2":6.70637,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-2","BTOXGR":"0","ADTM":"2019-07-12 18:23:33","ADY":33,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-365","SUBJID":"id-365","SITEID":"USA-11","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90915,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-09","TRTSDTM":"2019-06-09 18:23:33","TRTEDTM":"2022-02-14 01:28:19","TRT01SDTM":"2019-06-09 18:23:33","TRT01EDTM":"2021-02-13 19:28:19","TRT02SDTM":"2021-02-13 19:28:19","TRT02EDTM":"2022-02-14 01:28:19","AP01SDTM":"2019-06-09 18:23:33","AP01EDTM":"2021-02-13 19:28:19","AP02SDTM":"2021-02-13 19:28:19","AP02EDTM":"2022-02-14 01:28:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":981,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":1002,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4896,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.14696,"AVALU":"U/L","BASE2":6.70637,"BASE":31.14696,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":24.44059,"PCHG2":364.43854,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-20 18:23:33","ADY":41,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-365","SUBJID":"id-365","SITEID":"USA-11","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90915,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-09","TRTSDTM":"2019-06-09 18:23:33","TRTEDTM":"2022-02-14 01:28:19","TRT01SDTM":"2019-06-09 18:23:33","TRT01EDTM":"2021-02-13 19:28:19","TRT02SDTM":"2021-02-13 19:28:19","TRT02EDTM":"2022-02-14 01:28:19","AP01SDTM":"2019-06-09 18:23:33","AP01EDTM":"2021-02-13 19:28:19","AP02SDTM":"2021-02-13 19:28:19","AP02EDTM":"2022-02-14 01:28:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":981,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":1002,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1737,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.15696,"AVALU":"U/L","BASE2":6.70637,"BASE":31.14696,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":24.45059,"PCHG2":364.58763,"CHG":0.01,"PCHG":0.0321,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-20 18:23:33","ADY":225,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-365","SUBJID":"id-365","SITEID":"USA-11","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90915,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-09","TRTSDTM":"2019-06-09 18:23:33","TRTEDTM":"2022-02-14 01:28:19","TRT01SDTM":"2019-06-09 18:23:33","TRT01EDTM":"2021-02-13 19:28:19","TRT02SDTM":"2021-02-13 19:28:19","TRT02EDTM":"2022-02-14 01:28:19","AP01SDTM":"2019-06-09 18:23:33","AP01EDTM":"2021-02-13 19:28:19","AP02SDTM":"2021-02-13 19:28:19","AP02EDTM":"2022-02-14 01:28:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":981,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":1002,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5537,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.43609,"AVALU":"U/L","BASE2":6.70637,"BASE":31.14696,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.72972,"PCHG2":219.63782,"CHG":-9.71087,"PCHG":-31.17759,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-19 18:23:33","ADY":345,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-365","SUBJID":"id-365","SITEID":"USA-11","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90915,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-09","TRTSDTM":"2019-06-09 18:23:33","TRTEDTM":"2022-02-14 01:28:19","TRT01SDTM":"2019-06-09 18:23:33","TRT01EDTM":"2021-02-13 19:28:19","TRT02SDTM":"2021-02-13 19:28:19","TRT02EDTM":"2022-02-14 01:28:19","AP01SDTM":"2019-06-09 18:23:33","AP01EDTM":"2021-02-13 19:28:19","AP02SDTM":"2021-02-13 19:28:19","AP02EDTM":"2022-02-14 01:28:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":981,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":1002,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3010,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.34368,"AVALU":"U/L","BASE2":6.70637,"BASE":31.14696,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.36268,"PCHG2":-35.23045,"CHG":-26.80328,"PCHG":-86.05423,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-08-20 18:23:33","ADY":438,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-365","SUBJID":"id-365","SITEID":"USA-11","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90915,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-09","TRTSDTM":"2019-06-09 18:23:33","TRTEDTM":"2022-02-14 01:28:19","TRT01SDTM":"2019-06-09 18:23:33","TRT01EDTM":"2021-02-13 19:28:19","TRT02SDTM":"2021-02-13 19:28:19","TRT02EDTM":"2022-02-14 01:28:19","AP01SDTM":"2019-06-09 18:23:33","AP01EDTM":"2021-02-13 19:28:19","AP02SDTM":"2021-02-13 19:28:19","AP02EDTM":"2022-02-14 01:28:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":981,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":1002,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5882,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.48262,"AVALU":"U/L","BASE2":6.70637,"BASE":31.14696,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":14.77625,"PCHG2":220.33157,"CHG":-9.66435,"PCHG":-31.02821,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-21 18:23:33","ADY":592,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-365","SUBJID":"id-365","SITEID":"USA-11","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90915,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-09","TRTSDTM":"2019-06-09 18:23:33","TRTEDTM":"2022-02-14 01:28:19","TRT01SDTM":"2019-06-09 18:23:33","TRT01EDTM":"2021-02-13 19:28:19","TRT02SDTM":"2021-02-13 19:28:19","TRT02EDTM":"2022-02-14 01:28:19","AP01SDTM":"2019-06-09 18:23:33","AP01EDTM":"2021-02-13 19:28:19","AP02SDTM":"2021-02-13 19:28:19","AP02EDTM":"2022-02-14 01:28:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":981,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":1002,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3686,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.9852,"AVALU":"U/L","BASE2":6.70637,"BASE":31.14696,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.27883,"PCHG2":242.73681,"CHG":-8.16177,"PCHG":-26.20405,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-07 18:23:33","ADY":882,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-365","SUBJID":"id-365","SITEID":"USA-11","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90915,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-09","TRTSDTM":"2019-06-09 18:23:33","TRTEDTM":"2022-02-14 01:28:19","TRT01SDTM":"2019-06-09 18:23:33","TRT01EDTM":"2021-02-13 19:28:19","TRT02SDTM":"2021-02-13 19:28:19","TRT02EDTM":"2022-02-14 01:28:19","AP01SDTM":"2019-06-09 18:23:33","AP01EDTM":"2021-02-13 19:28:19","AP02SDTM":"2021-02-13 19:28:19","AP02EDTM":"2022-02-14 01:28:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":981,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":1002,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3170,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":11.13662,"AVALU":"mg/L","BASE2":11.13662,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"2","BTOXGR":"0","ADTM":"2019-07-12 18:23:33","ADY":33,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-365","SUBJID":"id-365","SITEID":"USA-11","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90915,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-09","TRTSDTM":"2019-06-09 18:23:33","TRTEDTM":"2022-02-14 01:28:19","TRT01SDTM":"2019-06-09 18:23:33","TRT01EDTM":"2021-02-13 19:28:19","TRT02SDTM":"2021-02-13 19:28:19","TRT02EDTM":"2022-02-14 01:28:19","AP01SDTM":"2019-06-09 18:23:33","AP01EDTM":"2021-02-13 19:28:19","AP02SDTM":"2021-02-13 19:28:19","AP02EDTM":"2022-02-14 01:28:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":981,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":1002,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1074,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.68612,"AVALU":"mg/L","BASE2":11.13662,"BASE":8.68612,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.45051,"PCHG2":-22.00403,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-20 18:23:33","ADY":41,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-365","SUBJID":"id-365","SITEID":"USA-11","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90915,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-09","TRTSDTM":"2019-06-09 18:23:33","TRTEDTM":"2022-02-14 01:28:19","TRT01SDTM":"2019-06-09 18:23:33","TRT01EDTM":"2021-02-13 19:28:19","TRT02SDTM":"2021-02-13 19:28:19","TRT02EDTM":"2022-02-14 01:28:19","AP01SDTM":"2019-06-09 18:23:33","AP01EDTM":"2021-02-13 19:28:19","AP02SDTM":"2021-02-13 19:28:19","AP02EDTM":"2022-02-14 01:28:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":981,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":1002,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7878,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.06102,"AVALU":"mg/L","BASE2":11.13662,"BASE":8.68612,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.0756,"PCHG2":-9.65821,"CHG":1.37491,"PCHG":15.8288,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2020-01-20 18:23:33","ADY":225,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-365","SUBJID":"id-365","SITEID":"USA-11","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90915,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-09","TRTSDTM":"2019-06-09 18:23:33","TRTEDTM":"2022-02-14 01:28:19","TRT01SDTM":"2019-06-09 18:23:33","TRT01EDTM":"2021-02-13 19:28:19","TRT02SDTM":"2021-02-13 19:28:19","TRT02EDTM":"2022-02-14 01:28:19","AP01SDTM":"2019-06-09 18:23:33","AP01EDTM":"2021-02-13 19:28:19","AP02SDTM":"2021-02-13 19:28:19","AP02EDTM":"2022-02-14 01:28:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":981,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":1002,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7648,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.31796,"AVALU":"mg/L","BASE2":11.13662,"BASE":8.68612,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.81866,"PCHG2":-16.33045,"CHG":0.63185,"PCHG":7.2742,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-19 18:23:33","ADY":345,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-365","SUBJID":"id-365","SITEID":"USA-11","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90915,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-09","TRTSDTM":"2019-06-09 18:23:33","TRTEDTM":"2022-02-14 01:28:19","TRT01SDTM":"2019-06-09 18:23:33","TRT01EDTM":"2021-02-13 19:28:19","TRT02SDTM":"2021-02-13 19:28:19","TRT02EDTM":"2022-02-14 01:28:19","AP01SDTM":"2019-06-09 18:23:33","AP01EDTM":"2021-02-13 19:28:19","AP02SDTM":"2021-02-13 19:28:19","AP02EDTM":"2022-02-14 01:28:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":981,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":1002,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7629,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.09817,"AVALU":"mg/L","BASE2":11.13662,"BASE":8.68612,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.03846,"PCHG2":-18.30409,"CHG":0.41205,"PCHG":4.74377,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-20 18:23:33","ADY":438,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-365","SUBJID":"id-365","SITEID":"USA-11","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90915,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-09","TRTSDTM":"2019-06-09 18:23:33","TRTEDTM":"2022-02-14 01:28:19","TRT01SDTM":"2019-06-09 18:23:33","TRT01EDTM":"2021-02-13 19:28:19","TRT02SDTM":"2021-02-13 19:28:19","TRT02EDTM":"2022-02-14 01:28:19","AP01SDTM":"2019-06-09 18:23:33","AP01EDTM":"2021-02-13 19:28:19","AP02SDTM":"2021-02-13 19:28:19","AP02EDTM":"2022-02-14 01:28:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":981,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":1002,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3511,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.94197,"AVALU":"mg/L","BASE2":11.13662,"BASE":8.68612,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.19465,"PCHG2":-19.70658,"CHG":0.25586,"PCHG":2.9456,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-21 18:23:33","ADY":592,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-365","SUBJID":"id-365","SITEID":"USA-11","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90915,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-09","TRTSDTM":"2019-06-09 18:23:33","TRTEDTM":"2022-02-14 01:28:19","TRT01SDTM":"2019-06-09 18:23:33","TRT01EDTM":"2021-02-13 19:28:19","TRT02SDTM":"2021-02-13 19:28:19","TRT02EDTM":"2022-02-14 01:28:19","AP01SDTM":"2019-06-09 18:23:33","AP01EDTM":"2021-02-13 19:28:19","AP02SDTM":"2021-02-13 19:28:19","AP02EDTM":"2022-02-14 01:28:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":981,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":1002,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4524,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.467,"AVALU":"mg/L","BASE2":11.13662,"BASE":8.68612,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.66962,"PCHG2":-23.97153,"CHG":-0.21911,"PCHG":-2.52257,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-07 18:23:33","ADY":882,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-365","SUBJID":"id-365","SITEID":"USA-11","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90915,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-09","TRTSDTM":"2019-06-09 18:23:33","TRTEDTM":"2022-02-14 01:28:19","TRT01SDTM":"2019-06-09 18:23:33","TRT01EDTM":"2021-02-13 19:28:19","TRT02SDTM":"2021-02-13 19:28:19","TRT02EDTM":"2022-02-14 01:28:19","AP01SDTM":"2019-06-09 18:23:33","AP01EDTM":"2021-02-13 19:28:19","AP02SDTM":"2021-02-13 19:28:19","AP02EDTM":"2022-02-14 01:28:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":981,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":1002,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6377,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81492,"AVALU":"g/L","BASE2":2.81492,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-12 18:23:33","ADY":33,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-365","SUBJID":"id-365","SITEID":"USA-11","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90915,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-09","TRTSDTM":"2019-06-09 18:23:33","TRTEDTM":"2022-02-14 01:28:19","TRT01SDTM":"2019-06-09 18:23:33","TRT01EDTM":"2021-02-13 19:28:19","TRT02SDTM":"2021-02-13 19:28:19","TRT02EDTM":"2022-02-14 01:28:19","AP01SDTM":"2019-06-09 18:23:33","AP01EDTM":"2021-02-13 19:28:19","AP02SDTM":"2021-02-13 19:28:19","AP02EDTM":"2022-02-14 01:28:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":981,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":1002,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4528,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96211,"AVALU":"g/L","BASE2":2.81492,"BASE":2.96211,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.14719,"PCHG2":5.22874,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-07-20 18:23:33","ADY":41,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-365","SUBJID":"id-365","SITEID":"USA-11","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90915,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-09","TRTSDTM":"2019-06-09 18:23:33","TRTEDTM":"2022-02-14 01:28:19","TRT01SDTM":"2019-06-09 18:23:33","TRT01EDTM":"2021-02-13 19:28:19","TRT02SDTM":"2021-02-13 19:28:19","TRT02EDTM":"2022-02-14 01:28:19","AP01SDTM":"2019-06-09 18:23:33","AP01EDTM":"2021-02-13 19:28:19","AP02SDTM":"2021-02-13 19:28:19","AP02EDTM":"2022-02-14 01:28:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":981,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":1002,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6808,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75688,"AVALU":"g/L","BASE2":2.81492,"BASE":2.96211,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05805,"PCHG2":-2.06209,"CHG":-0.20523,"PCHG":-6.92855,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-01-20 18:23:33","ADY":225,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-365","SUBJID":"id-365","SITEID":"USA-11","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90915,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-09","TRTSDTM":"2019-06-09 18:23:33","TRTEDTM":"2022-02-14 01:28:19","TRT01SDTM":"2019-06-09 18:23:33","TRT01EDTM":"2021-02-13 19:28:19","TRT02SDTM":"2021-02-13 19:28:19","TRT02EDTM":"2022-02-14 01:28:19","AP01SDTM":"2019-06-09 18:23:33","AP01EDTM":"2021-02-13 19:28:19","AP02SDTM":"2021-02-13 19:28:19","AP02EDTM":"2022-02-14 01:28:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":981,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":1002,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2584,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96098,"AVALU":"g/L","BASE2":2.81492,"BASE":2.96211,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14605,"PCHG2":5.18856,"CHG":-0.00113,"PCHG":-0.03819,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-19 18:23:33","ADY":345,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-365","SUBJID":"id-365","SITEID":"USA-11","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90915,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-09","TRTSDTM":"2019-06-09 18:23:33","TRTEDTM":"2022-02-14 01:28:19","TRT01SDTM":"2019-06-09 18:23:33","TRT01EDTM":"2021-02-13 19:28:19","TRT02SDTM":"2021-02-13 19:28:19","TRT02EDTM":"2022-02-14 01:28:19","AP01SDTM":"2019-06-09 18:23:33","AP01EDTM":"2021-02-13 19:28:19","AP02SDTM":"2021-02-13 19:28:19","AP02EDTM":"2022-02-14 01:28:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":981,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":1002,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7584,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75446,"AVALU":"g/L","BASE2":2.81492,"BASE":2.96211,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06047,"PCHG2":-2.14812,"CHG":-0.20765,"PCHG":-7.01031,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-20 18:23:33","ADY":438,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-365","SUBJID":"id-365","SITEID":"USA-11","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90915,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-09","TRTSDTM":"2019-06-09 18:23:33","TRTEDTM":"2022-02-14 01:28:19","TRT01SDTM":"2019-06-09 18:23:33","TRT01EDTM":"2021-02-13 19:28:19","TRT02SDTM":"2021-02-13 19:28:19","TRT02EDTM":"2022-02-14 01:28:19","AP01SDTM":"2019-06-09 18:23:33","AP01EDTM":"2021-02-13 19:28:19","AP02SDTM":"2021-02-13 19:28:19","AP02EDTM":"2022-02-14 01:28:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":981,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":1002,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3488,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.58592,"AVALU":"g/L","BASE2":2.81492,"BASE":2.96211,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.229,"PCHG2":-8.13526,"CHG":-0.37619,"PCHG":-12.69995,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-21 18:23:33","ADY":592,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-11-id-365","SUBJID":"id-365","SITEID":"USA-11","AGE":34,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-11","INVNAM":"Dr. USA-11 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":1.90915,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-06-09","TRTSDTM":"2019-06-09 18:23:33","TRTEDTM":"2022-02-14 01:28:19","TRT01SDTM":"2019-06-09 18:23:33","TRT01EDTM":"2021-02-13 19:28:19","TRT02SDTM":"2021-02-13 19:28:19","TRT02EDTM":"2022-02-14 01:28:19","AP01SDTM":"2019-06-09 18:23:33","AP01EDTM":"2021-02-13 19:28:19","AP02SDTM":"2021-02-13 19:28:19","AP02EDTM":"2022-02-14 01:28:19","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":981,"DCSREAS":"DEATH","DTHDT":"2022-03-08","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":22,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-08","DTHADY":1002,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":420,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93928,"AVALU":"g/L","BASE2":2.81492,"BASE":2.96211,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.12436,"PCHG2":4.41788,"CHG":-0.02283,"PCHG":-0.77057,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-07 18:23:33","ADY":882,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-131","SUBJID":"id-131","SITEID":"USA-12","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.72694,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-02-14","TRTSDTM":"2021-02-17 15:03:58","TRTEDTM":"2024-02-18 09:03:58","TRT01SDTM":"2021-02-17 15:03:58","TRT01EDTM":"2023-02-18 03:03:58","TRT02SDTM":"2023-02-18 03:03:58","TRT02EDTM":"2024-02-18 09:03:58","AP01SDTM":"2021-02-17 15:03:58","AP01EDTM":"2023-02-18 03:03:58","AP02SDTM":"2023-02-18 03:03:58","AP02EDTM":"2024-02-18 09:03:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-18","EOSDY":1096,"LSTALVDT":"2024-03-07","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7772,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.65223,"AVALU":"U/L","BASE2":26.65223,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-08 15:03:58","ADY":233,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-131","SUBJID":"id-131","SITEID":"USA-12","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.72694,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-02-14","TRTSDTM":"2021-02-17 15:03:58","TRTEDTM":"2024-02-18 09:03:58","TRT01SDTM":"2021-02-17 15:03:58","TRT01EDTM":"2023-02-18 03:03:58","TRT02SDTM":"2023-02-18 03:03:58","TRT02EDTM":"2024-02-18 09:03:58","AP01SDTM":"2021-02-17 15:03:58","AP01EDTM":"2023-02-18 03:03:58","AP02SDTM":"2023-02-18 03:03:58","AP02EDTM":"2024-02-18 09:03:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-18","EOSDY":1096,"LSTALVDT":"2024-03-07","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8397,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.17463,"AVALU":"U/L","BASE2":26.65223,"BASE":18.17463,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-8.4776,"PCHG2":-31.80821,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-26 15:03:58","ADY":251,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-131","SUBJID":"id-131","SITEID":"USA-12","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.72694,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-02-14","TRTSDTM":"2021-02-17 15:03:58","TRTEDTM":"2024-02-18 09:03:58","TRT01SDTM":"2021-02-17 15:03:58","TRT01EDTM":"2023-02-18 03:03:58","TRT02SDTM":"2023-02-18 03:03:58","TRT02EDTM":"2024-02-18 09:03:58","AP01SDTM":"2021-02-17 15:03:58","AP01EDTM":"2023-02-18 03:03:58","AP02SDTM":"2023-02-18 03:03:58","AP02EDTM":"2024-02-18 09:03:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-18","EOSDY":1096,"LSTALVDT":"2024-03-07","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4218,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.6183,"AVALU":"U/L","BASE2":26.65223,"BASE":18.17463,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-21.03393,"PCHG2":-78.91998,"CHG":-12.55634,"PCHG":-69.08715,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2022-04-30 15:03:58","ADY":437,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-131","SUBJID":"id-131","SITEID":"USA-12","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.72694,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-02-14","TRTSDTM":"2021-02-17 15:03:58","TRTEDTM":"2024-02-18 09:03:58","TRT01SDTM":"2021-02-17 15:03:58","TRT01EDTM":"2023-02-18 03:03:58","TRT02SDTM":"2023-02-18 03:03:58","TRT02EDTM":"2024-02-18 09:03:58","AP01SDTM":"2021-02-17 15:03:58","AP01EDTM":"2023-02-18 03:03:58","AP02SDTM":"2023-02-18 03:03:58","AP02EDTM":"2024-02-18 09:03:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-18","EOSDY":1096,"LSTALVDT":"2024-03-07","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8366,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.86687,"AVALU":"U/L","BASE2":26.65223,"BASE":18.17463,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-17.78536,"PCHG2":-66.73123,"CHG":-9.30776,"PCHG":-51.21294,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-30 15:03:58","ADY":498,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-131","SUBJID":"id-131","SITEID":"USA-12","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.72694,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-02-14","TRTSDTM":"2021-02-17 15:03:58","TRTEDTM":"2024-02-18 09:03:58","TRT01SDTM":"2021-02-17 15:03:58","TRT01EDTM":"2023-02-18 03:03:58","TRT02SDTM":"2023-02-18 03:03:58","TRT02EDTM":"2024-02-18 09:03:58","AP01SDTM":"2021-02-17 15:03:58","AP01EDTM":"2023-02-18 03:03:58","AP02SDTM":"2023-02-18 03:03:58","AP02EDTM":"2024-02-18 09:03:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-18","EOSDY":1096,"LSTALVDT":"2024-03-07","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6020,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.10196,"AVALU":"U/L","BASE2":26.65223,"BASE":18.17463,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.55027,"PCHG2":-54.59307,"CHG":-6.07267,"PCHG":-33.4129,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-14 15:03:58","ADY":604,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-131","SUBJID":"id-131","SITEID":"USA-12","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.72694,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-02-14","TRTSDTM":"2021-02-17 15:03:58","TRTEDTM":"2024-02-18 09:03:58","TRT01SDTM":"2021-02-17 15:03:58","TRT01EDTM":"2023-02-18 03:03:58","TRT02SDTM":"2023-02-18 03:03:58","TRT02EDTM":"2024-02-18 09:03:58","AP01SDTM":"2021-02-17 15:03:58","AP01EDTM":"2023-02-18 03:03:58","AP02SDTM":"2023-02-18 03:03:58","AP02EDTM":"2024-02-18 09:03:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-18","EOSDY":1096,"LSTALVDT":"2024-03-07","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":258,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":35.23023,"AVALU":"U/L","BASE2":26.65223,"BASE":18.17463,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.578,"PCHG2":32.18493,"CHG":17.0556,"PCHG":93.84288,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-15 15:03:58","ADY":636,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-131","SUBJID":"id-131","SITEID":"USA-12","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.72694,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-02-14","TRTSDTM":"2021-02-17 15:03:58","TRTEDTM":"2024-02-18 09:03:58","TRT01SDTM":"2021-02-17 15:03:58","TRT01EDTM":"2023-02-18 03:03:58","TRT02SDTM":"2023-02-18 03:03:58","TRT02EDTM":"2024-02-18 09:03:58","AP01SDTM":"2021-02-17 15:03:58","AP01EDTM":"2023-02-18 03:03:58","AP02SDTM":"2023-02-18 03:03:58","AP02EDTM":"2024-02-18 09:03:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-18","EOSDY":1096,"LSTALVDT":"2024-03-07","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3406,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":43.42392,"AVALU":"U/L","BASE2":26.65223,"BASE":18.17463,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.77169,"PCHG2":62.92789,"CHG":25.24928,"PCHG":138.92597,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-08 15:03:58","ADY":902,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-131","SUBJID":"id-131","SITEID":"USA-12","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.72694,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-02-14","TRTSDTM":"2021-02-17 15:03:58","TRTEDTM":"2024-02-18 09:03:58","TRT01SDTM":"2021-02-17 15:03:58","TRT01EDTM":"2023-02-18 03:03:58","TRT02SDTM":"2023-02-18 03:03:58","TRT02EDTM":"2024-02-18 09:03:58","AP01SDTM":"2021-02-17 15:03:58","AP01EDTM":"2023-02-18 03:03:58","AP02SDTM":"2023-02-18 03:03:58","AP02EDTM":"2024-02-18 09:03:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-18","EOSDY":1096,"LSTALVDT":"2024-03-07","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1052,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.14521,"AVALU":"mg/L","BASE2":7.14521,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-10-08 15:03:58","ADY":233,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-131","SUBJID":"id-131","SITEID":"USA-12","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.72694,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-02-14","TRTSDTM":"2021-02-17 15:03:58","TRTEDTM":"2024-02-18 09:03:58","TRT01SDTM":"2021-02-17 15:03:58","TRT01EDTM":"2023-02-18 03:03:58","TRT02SDTM":"2023-02-18 03:03:58","TRT02EDTM":"2024-02-18 09:03:58","AP01SDTM":"2021-02-17 15:03:58","AP01EDTM":"2023-02-18 03:03:58","AP02SDTM":"2023-02-18 03:03:58","AP02EDTM":"2024-02-18 09:03:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-18","EOSDY":1096,"LSTALVDT":"2024-03-07","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4308,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.47611,"AVALU":"mg/L","BASE2":7.14521,"BASE":8.47611,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.3309,"PCHG2":18.62646,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-26 15:03:58","ADY":251,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-131","SUBJID":"id-131","SITEID":"USA-12","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.72694,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-02-14","TRTSDTM":"2021-02-17 15:03:58","TRTEDTM":"2024-02-18 09:03:58","TRT01SDTM":"2021-02-17 15:03:58","TRT01EDTM":"2023-02-18 03:03:58","TRT02SDTM":"2023-02-18 03:03:58","TRT02EDTM":"2024-02-18 09:03:58","AP01SDTM":"2021-02-17 15:03:58","AP01EDTM":"2023-02-18 03:03:58","AP02SDTM":"2023-02-18 03:03:58","AP02EDTM":"2024-02-18 09:03:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-18","EOSDY":1096,"LSTALVDT":"2024-03-07","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7728,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.73297,"AVALU":"mg/L","BASE2":7.14521,"BASE":8.47611,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.58776,"PCHG2":22.22137,"CHG":0.25686,"PCHG":3.03044,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-30 15:03:58","ADY":437,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-131","SUBJID":"id-131","SITEID":"USA-12","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.72694,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-02-14","TRTSDTM":"2021-02-17 15:03:58","TRTEDTM":"2024-02-18 09:03:58","TRT01SDTM":"2021-02-17 15:03:58","TRT01EDTM":"2023-02-18 03:03:58","TRT02SDTM":"2023-02-18 03:03:58","TRT02EDTM":"2024-02-18 09:03:58","AP01SDTM":"2021-02-17 15:03:58","AP01EDTM":"2023-02-18 03:03:58","AP02SDTM":"2023-02-18 03:03:58","AP02EDTM":"2024-02-18 09:03:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-18","EOSDY":1096,"LSTALVDT":"2024-03-07","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2614,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.13639,"AVALU":"mg/L","BASE2":7.14521,"BASE":8.47611,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00882,"PCHG2":-0.12347,"CHG":-1.33972,"PCHG":-15.80586,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-06-30 15:03:58","ADY":498,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-131","SUBJID":"id-131","SITEID":"USA-12","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.72694,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-02-14","TRTSDTM":"2021-02-17 15:03:58","TRTEDTM":"2024-02-18 09:03:58","TRT01SDTM":"2021-02-17 15:03:58","TRT01EDTM":"2023-02-18 03:03:58","TRT02SDTM":"2023-02-18 03:03:58","TRT02EDTM":"2024-02-18 09:03:58","AP01SDTM":"2021-02-17 15:03:58","AP01EDTM":"2023-02-18 03:03:58","AP02SDTM":"2023-02-18 03:03:58","AP02EDTM":"2024-02-18 09:03:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-18","EOSDY":1096,"LSTALVDT":"2024-03-07","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7938,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.63641,"AVALU":"mg/L","BASE2":7.14521,"BASE":8.47611,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.49121,"PCHG2":20.87002,"CHG":0.16031,"PCHG":1.89128,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-14 15:03:58","ADY":604,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-131","SUBJID":"id-131","SITEID":"USA-12","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.72694,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-02-14","TRTSDTM":"2021-02-17 15:03:58","TRTEDTM":"2024-02-18 09:03:58","TRT01SDTM":"2021-02-17 15:03:58","TRT01EDTM":"2023-02-18 03:03:58","TRT02SDTM":"2023-02-18 03:03:58","TRT02EDTM":"2024-02-18 09:03:58","AP01SDTM":"2021-02-17 15:03:58","AP01EDTM":"2023-02-18 03:03:58","AP02SDTM":"2023-02-18 03:03:58","AP02EDTM":"2024-02-18 09:03:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-18","EOSDY":1096,"LSTALVDT":"2024-03-07","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6587,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.81492,"AVALU":"mg/L","BASE2":7.14521,"BASE":8.47611,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.66971,"PCHG2":9.37286,"CHG":-0.66119,"PCHG":-7.80062,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-11-15 15:03:58","ADY":636,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-131","SUBJID":"id-131","SITEID":"USA-12","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.72694,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-02-14","TRTSDTM":"2021-02-17 15:03:58","TRTEDTM":"2024-02-18 09:03:58","TRT01SDTM":"2021-02-17 15:03:58","TRT01EDTM":"2023-02-18 03:03:58","TRT02SDTM":"2023-02-18 03:03:58","TRT02EDTM":"2024-02-18 09:03:58","AP01SDTM":"2021-02-17 15:03:58","AP01EDTM":"2023-02-18 03:03:58","AP02SDTM":"2023-02-18 03:03:58","AP02EDTM":"2024-02-18 09:03:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-18","EOSDY":1096,"LSTALVDT":"2024-03-07","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5450,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.45707,"AVALU":"mg/L","BASE2":7.14521,"BASE":8.47611,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.31186,"PCHG2":32.35543,"CHG":0.98096,"PCHG":11.57328,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-08 15:03:58","ADY":902,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-131","SUBJID":"id-131","SITEID":"USA-12","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.72694,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-02-14","TRTSDTM":"2021-02-17 15:03:58","TRTEDTM":"2024-02-18 09:03:58","TRT01SDTM":"2021-02-17 15:03:58","TRT01EDTM":"2023-02-18 03:03:58","TRT02SDTM":"2023-02-18 03:03:58","TRT02EDTM":"2024-02-18 09:03:58","AP01SDTM":"2021-02-17 15:03:58","AP01EDTM":"2023-02-18 03:03:58","AP02SDTM":"2023-02-18 03:03:58","AP02EDTM":"2024-02-18 09:03:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-18","EOSDY":1096,"LSTALVDT":"2024-03-07","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4270,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93468,"AVALU":"g/L","BASE2":2.93468,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-08 15:03:58","ADY":233,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-131","SUBJID":"id-131","SITEID":"USA-12","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.72694,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-02-14","TRTSDTM":"2021-02-17 15:03:58","TRTEDTM":"2024-02-18 09:03:58","TRT01SDTM":"2021-02-17 15:03:58","TRT01EDTM":"2023-02-18 03:03:58","TRT02SDTM":"2023-02-18 03:03:58","TRT02EDTM":"2024-02-18 09:03:58","AP01SDTM":"2021-02-17 15:03:58","AP01EDTM":"2023-02-18 03:03:58","AP02SDTM":"2023-02-18 03:03:58","AP02EDTM":"2024-02-18 09:03:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-18","EOSDY":1096,"LSTALVDT":"2024-03-07","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4977,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9167,"AVALU":"g/L","BASE2":2.93468,"BASE":2.9167,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.01797,"PCHG2":-0.61249,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-26 15:03:58","ADY":251,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-131","SUBJID":"id-131","SITEID":"USA-12","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.72694,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-02-14","TRTSDTM":"2021-02-17 15:03:58","TRTEDTM":"2024-02-18 09:03:58","TRT01SDTM":"2021-02-17 15:03:58","TRT01EDTM":"2023-02-18 03:03:58","TRT02SDTM":"2023-02-18 03:03:58","TRT02EDTM":"2024-02-18 09:03:58","AP01SDTM":"2021-02-17 15:03:58","AP01EDTM":"2023-02-18 03:03:58","AP02SDTM":"2023-02-18 03:03:58","AP02EDTM":"2024-02-18 09:03:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-18","EOSDY":1096,"LSTALVDT":"2024-03-07","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1305,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81555,"AVALU":"g/L","BASE2":2.93468,"BASE":2.9167,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.11913,"PCHG2":-4.05925,"CHG":-0.10115,"PCHG":-3.468,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-04-30 15:03:58","ADY":437,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-131","SUBJID":"id-131","SITEID":"USA-12","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.72694,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-02-14","TRTSDTM":"2021-02-17 15:03:58","TRTEDTM":"2024-02-18 09:03:58","TRT01SDTM":"2021-02-17 15:03:58","TRT01EDTM":"2023-02-18 03:03:58","TRT02SDTM":"2023-02-18 03:03:58","TRT02EDTM":"2024-02-18 09:03:58","AP01SDTM":"2021-02-17 15:03:58","AP01EDTM":"2023-02-18 03:03:58","AP02SDTM":"2023-02-18 03:03:58","AP02EDTM":"2024-02-18 09:03:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-18","EOSDY":1096,"LSTALVDT":"2024-03-07","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":705,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83796,"AVALU":"g/L","BASE2":2.93468,"BASE":2.9167,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09671,"PCHG2":-3.29551,"CHG":-0.07874,"PCHG":-2.69956,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-06-30 15:03:58","ADY":498,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-131","SUBJID":"id-131","SITEID":"USA-12","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.72694,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-02-14","TRTSDTM":"2021-02-17 15:03:58","TRTEDTM":"2024-02-18 09:03:58","TRT01SDTM":"2021-02-17 15:03:58","TRT01EDTM":"2023-02-18 03:03:58","TRT02SDTM":"2023-02-18 03:03:58","TRT02EDTM":"2024-02-18 09:03:58","AP01SDTM":"2021-02-17 15:03:58","AP01EDTM":"2023-02-18 03:03:58","AP02SDTM":"2023-02-18 03:03:58","AP02EDTM":"2024-02-18 09:03:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-18","EOSDY":1096,"LSTALVDT":"2024-03-07","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8340,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85196,"AVALU":"g/L","BASE2":2.93468,"BASE":2.9167,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08272,"PCHG2":-2.8187,"CHG":-0.06475,"PCHG":-2.21981,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-14 15:03:58","ADY":604,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-131","SUBJID":"id-131","SITEID":"USA-12","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.72694,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-02-14","TRTSDTM":"2021-02-17 15:03:58","TRTEDTM":"2024-02-18 09:03:58","TRT01SDTM":"2021-02-17 15:03:58","TRT01EDTM":"2023-02-18 03:03:58","TRT02SDTM":"2023-02-18 03:03:58","TRT02EDTM":"2024-02-18 09:03:58","AP01SDTM":"2021-02-17 15:03:58","AP01EDTM":"2023-02-18 03:03:58","AP02SDTM":"2023-02-18 03:03:58","AP02EDTM":"2024-02-18 09:03:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-18","EOSDY":1096,"LSTALVDT":"2024-03-07","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5928,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94199,"AVALU":"g/L","BASE2":2.93468,"BASE":2.9167,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00731,"PCHG2":0.24921,"CHG":0.02529,"PCHG":0.867,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-15 15:03:58","ADY":636,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-131","SUBJID":"id-131","SITEID":"USA-12","AGE":44,"AGEU":"YEARS","SEX":"F","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.72694,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2021-02-14","TRTSDTM":"2021-02-17 15:03:58","TRTEDTM":"2024-02-18 09:03:58","TRT01SDTM":"2021-02-17 15:03:58","TRT01EDTM":"2023-02-18 03:03:58","TRT02SDTM":"2023-02-18 03:03:58","TRT02EDTM":"2024-02-18 09:03:58","AP01SDTM":"2021-02-17 15:03:58","AP01EDTM":"2023-02-18 03:03:58","AP02SDTM":"2023-02-18 03:03:58","AP02EDTM":"2024-02-18 09:03:58","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2024-02-18","EOSDY":1096,"LSTALVDT":"2024-03-07","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5364,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89024,"AVALU":"g/L","BASE2":2.93468,"BASE":2.9167,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04444,"PCHG2":-1.5142,"CHG":-0.02646,"PCHG":-0.90727,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-08-08 15:03:58","ADY":902,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-140","SUBJID":"id-140","SITEID":"USA-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":14.22993,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-03","TRTSDTM":"2020-07-05 21:31:45","TRTEDTM":"2022-02-16 15:46:45","TRT01SDTM":"2020-07-05 21:31:45","TRT01EDTM":"2021-02-16 09:46:45","TRT02SDTM":"2021-02-16 09:46:45","TRT02EDTM":"2022-02-16 15:46:45","AP01SDTM":"2020-07-05 21:31:45","AP01EDTM":"2021-02-16 09:46:45","AP02SDTM":"2021-02-16 09:46:45","AP02EDTM":"2022-02-16 15:46:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":591,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-05","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7177,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.30207,"AVALU":"U/L","BASE2":29.30207,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-12 21:31:45","ADY":38,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-140","SUBJID":"id-140","SITEID":"USA-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":14.22993,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-03","TRTSDTM":"2020-07-05 21:31:45","TRTEDTM":"2022-02-16 15:46:45","TRT01SDTM":"2020-07-05 21:31:45","TRT01EDTM":"2021-02-16 09:46:45","TRT02SDTM":"2021-02-16 09:46:45","TRT02EDTM":"2022-02-16 15:46:45","AP01SDTM":"2020-07-05 21:31:45","AP01EDTM":"2021-02-16 09:46:45","AP02SDTM":"2021-02-16 09:46:45","AP02EDTM":"2022-02-16 15:46:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":591,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-05","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8200,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.19029,"AVALU":"U/L","BASE2":29.30207,"BASE":12.19029,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-17.11179,"PCHG2":-58.39787,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-13 21:31:45","ADY":70,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-140","SUBJID":"id-140","SITEID":"USA-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":14.22993,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-03","TRTSDTM":"2020-07-05 21:31:45","TRTEDTM":"2022-02-16 15:46:45","TRT01SDTM":"2020-07-05 21:31:45","TRT01EDTM":"2021-02-16 09:46:45","TRT02SDTM":"2021-02-16 09:46:45","TRT02EDTM":"2022-02-16 15:46:45","AP01SDTM":"2020-07-05 21:31:45","AP01EDTM":"2021-02-16 09:46:45","AP02SDTM":"2021-02-16 09:46:45","AP02EDTM":"2022-02-16 15:46:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":591,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-05","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8061,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":36.17723,"AVALU":"U/L","BASE2":29.30207,"BASE":12.19029,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.87516,"PCHG2":23.46304,"CHG":23.98694,"PCHG":196.77094,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-07 21:31:45","ADY":186,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-140","SUBJID":"id-140","SITEID":"USA-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":14.22993,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-03","TRTSDTM":"2020-07-05 21:31:45","TRTEDTM":"2022-02-16 15:46:45","TRT01SDTM":"2020-07-05 21:31:45","TRT01EDTM":"2021-02-16 09:46:45","TRT02SDTM":"2021-02-16 09:46:45","TRT02EDTM":"2022-02-16 15:46:45","AP01SDTM":"2020-07-05 21:31:45","AP01EDTM":"2021-02-16 09:46:45","AP02SDTM":"2021-02-16 09:46:45","AP02EDTM":"2022-02-16 15:46:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":591,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-05","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4821,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.26651,"AVALU":"U/L","BASE2":29.30207,"BASE":12.19029,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-18.03557,"PCHG2":-61.55048,"CHG":-0.92378,"PCHG":-7.578,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-29 21:31:45","ADY":328,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-140","SUBJID":"id-140","SITEID":"USA-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":14.22993,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-03","TRTSDTM":"2020-07-05 21:31:45","TRTEDTM":"2022-02-16 15:46:45","TRT01SDTM":"2020-07-05 21:31:45","TRT01EDTM":"2021-02-16 09:46:45","TRT02SDTM":"2021-02-16 09:46:45","TRT02EDTM":"2022-02-16 15:46:45","AP01SDTM":"2020-07-05 21:31:45","AP01EDTM":"2021-02-16 09:46:45","AP02SDTM":"2021-02-16 09:46:45","AP02EDTM":"2022-02-16 15:46:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":591,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-05","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":845,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":37.64922,"AVALU":"U/L","BASE2":29.30207,"BASE":12.19029,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.34715,"PCHG2":28.48656,"CHG":25.45894,"PCHG":208.84609,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-04 21:31:45","ADY":334,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-140","SUBJID":"id-140","SITEID":"USA-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":14.22993,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-03","TRTSDTM":"2020-07-05 21:31:45","TRTEDTM":"2022-02-16 15:46:45","TRT01SDTM":"2020-07-05 21:31:45","TRT01EDTM":"2021-02-16 09:46:45","TRT02SDTM":"2021-02-16 09:46:45","TRT02EDTM":"2022-02-16 15:46:45","AP01SDTM":"2020-07-05 21:31:45","AP01EDTM":"2021-02-16 09:46:45","AP02SDTM":"2021-02-16 09:46:45","AP02EDTM":"2022-02-16 15:46:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":591,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-05","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6409,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.34918,"AVALU":"U/L","BASE2":29.30207,"BASE":12.19029,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.95289,"PCHG2":-13.49015,"CHG":13.15889,"PCHG":107.94572,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-14 21:31:45","ADY":436,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-140","SUBJID":"id-140","SITEID":"USA-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":14.22993,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-03","TRTSDTM":"2020-07-05 21:31:45","TRTEDTM":"2022-02-16 15:46:45","TRT01SDTM":"2020-07-05 21:31:45","TRT01EDTM":"2021-02-16 09:46:45","TRT02SDTM":"2021-02-16 09:46:45","TRT02EDTM":"2022-02-16 15:46:45","AP01SDTM":"2020-07-05 21:31:45","AP01EDTM":"2021-02-16 09:46:45","AP02SDTM":"2021-02-16 09:46:45","AP02EDTM":"2022-02-16 15:46:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":591,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-05","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":535,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.51597,"AVALU":"U/L","BASE2":29.30207,"BASE":12.19029,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.78611,"PCHG2":-33.39732,"CHG":7.32568,"PCHG":60.09439,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-16 21:31:45","ADY":499,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-140","SUBJID":"id-140","SITEID":"USA-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":14.22993,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-03","TRTSDTM":"2020-07-05 21:31:45","TRTEDTM":"2022-02-16 15:46:45","TRT01SDTM":"2020-07-05 21:31:45","TRT01EDTM":"2021-02-16 09:46:45","TRT02SDTM":"2021-02-16 09:46:45","TRT02EDTM":"2022-02-16 15:46:45","AP01SDTM":"2020-07-05 21:31:45","AP01EDTM":"2021-02-16 09:46:45","AP02SDTM":"2021-02-16 09:46:45","AP02EDTM":"2022-02-16 15:46:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":591,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-05","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7830,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.68261,"AVALU":"mg/L","BASE2":8.68261,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-12 21:31:45","ADY":38,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-140","SUBJID":"id-140","SITEID":"USA-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":14.22993,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-03","TRTSDTM":"2020-07-05 21:31:45","TRTEDTM":"2022-02-16 15:46:45","TRT01SDTM":"2020-07-05 21:31:45","TRT01EDTM":"2021-02-16 09:46:45","TRT02SDTM":"2021-02-16 09:46:45","TRT02EDTM":"2022-02-16 15:46:45","AP01SDTM":"2020-07-05 21:31:45","AP01EDTM":"2021-02-16 09:46:45","AP02SDTM":"2021-02-16 09:46:45","AP02EDTM":"2022-02-16 15:46:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":591,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-05","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2397,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.26964,"AVALU":"mg/L","BASE2":8.68261,"BASE":9.26964,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.58704,"PCHG2":6.76107,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-13 21:31:45","ADY":70,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-140","SUBJID":"id-140","SITEID":"USA-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":14.22993,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-03","TRTSDTM":"2020-07-05 21:31:45","TRTEDTM":"2022-02-16 15:46:45","TRT01SDTM":"2020-07-05 21:31:45","TRT01EDTM":"2021-02-16 09:46:45","TRT02SDTM":"2021-02-16 09:46:45","TRT02EDTM":"2022-02-16 15:46:45","AP01SDTM":"2020-07-05 21:31:45","AP01EDTM":"2021-02-16 09:46:45","AP02SDTM":"2021-02-16 09:46:45","AP02EDTM":"2022-02-16 15:46:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":591,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-05","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3100,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.2068,"AVALU":"mg/L","BASE2":8.68261,"BASE":9.26964,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.4758,"PCHG2":-5.47997,"CHG":-1.06284,"PCHG":-11.46583,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-07 21:31:45","ADY":186,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-140","SUBJID":"id-140","SITEID":"USA-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":14.22993,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-03","TRTSDTM":"2020-07-05 21:31:45","TRTEDTM":"2022-02-16 15:46:45","TRT01SDTM":"2020-07-05 21:31:45","TRT01EDTM":"2021-02-16 09:46:45","TRT02SDTM":"2021-02-16 09:46:45","TRT02EDTM":"2022-02-16 15:46:45","AP01SDTM":"2020-07-05 21:31:45","AP01EDTM":"2021-02-16 09:46:45","AP02SDTM":"2021-02-16 09:46:45","AP02EDTM":"2022-02-16 15:46:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":591,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-05","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8171,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.38242,"AVALU":"mg/L","BASE2":8.68261,"BASE":9.26964,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.30019,"PCHG2":-3.45739,"CHG":-0.88723,"PCHG":-9.57133,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-29 21:31:45","ADY":328,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-140","SUBJID":"id-140","SITEID":"USA-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":14.22993,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-03","TRTSDTM":"2020-07-05 21:31:45","TRTEDTM":"2022-02-16 15:46:45","TRT01SDTM":"2020-07-05 21:31:45","TRT01EDTM":"2021-02-16 09:46:45","TRT02SDTM":"2021-02-16 09:46:45","TRT02EDTM":"2022-02-16 15:46:45","AP01SDTM":"2020-07-05 21:31:45","AP01EDTM":"2021-02-16 09:46:45","AP02SDTM":"2021-02-16 09:46:45","AP02EDTM":"2022-02-16 15:46:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":591,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-05","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4670,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.0549,"AVALU":"mg/L","BASE2":8.68261,"BASE":9.26964,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.3723,"PCHG2":15.80513,"CHG":0.78526,"PCHG":8.47131,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-06-04 21:31:45","ADY":334,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-140","SUBJID":"id-140","SITEID":"USA-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":14.22993,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-03","TRTSDTM":"2020-07-05 21:31:45","TRTEDTM":"2022-02-16 15:46:45","TRT01SDTM":"2020-07-05 21:31:45","TRT01EDTM":"2021-02-16 09:46:45","TRT02SDTM":"2021-02-16 09:46:45","TRT02EDTM":"2022-02-16 15:46:45","AP01SDTM":"2020-07-05 21:31:45","AP01EDTM":"2021-02-16 09:46:45","AP02SDTM":"2021-02-16 09:46:45","AP02EDTM":"2022-02-16 15:46:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":591,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-05","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5480,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.99027,"AVALU":"mg/L","BASE2":8.68261,"BASE":9.26964,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.69233,"PCHG2":-7.97379,"CHG":-1.27937,"PCHG":-13.80171,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-09-14 21:31:45","ADY":436,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-140","SUBJID":"id-140","SITEID":"USA-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":14.22993,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-03","TRTSDTM":"2020-07-05 21:31:45","TRTEDTM":"2022-02-16 15:46:45","TRT01SDTM":"2020-07-05 21:31:45","TRT01EDTM":"2021-02-16 09:46:45","TRT02SDTM":"2021-02-16 09:46:45","TRT02EDTM":"2022-02-16 15:46:45","AP01SDTM":"2020-07-05 21:31:45","AP01EDTM":"2021-02-16 09:46:45","AP02SDTM":"2021-02-16 09:46:45","AP02EDTM":"2022-02-16 15:46:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":591,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-05","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2986,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.49199,"AVALU":"mg/L","BASE2":8.68261,"BASE":9.26964,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.19062,"PCHG2":-13.71268,"CHG":-1.77766,"PCHG":-19.17717,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-11-16 21:31:45","ADY":499,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-140","SUBJID":"id-140","SITEID":"USA-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":14.22993,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-03","TRTSDTM":"2020-07-05 21:31:45","TRTEDTM":"2022-02-16 15:46:45","TRT01SDTM":"2020-07-05 21:31:45","TRT01EDTM":"2021-02-16 09:46:45","TRT02SDTM":"2021-02-16 09:46:45","TRT02EDTM":"2022-02-16 15:46:45","AP01SDTM":"2020-07-05 21:31:45","AP01EDTM":"2021-02-16 09:46:45","AP02SDTM":"2021-02-16 09:46:45","AP02EDTM":"2022-02-16 15:46:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":591,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-05","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3575,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82416,"AVALU":"g/L","BASE2":2.82416,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-12 21:31:45","ADY":38,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-140","SUBJID":"id-140","SITEID":"USA-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":14.22993,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-03","TRTSDTM":"2020-07-05 21:31:45","TRTEDTM":"2022-02-16 15:46:45","TRT01SDTM":"2020-07-05 21:31:45","TRT01EDTM":"2021-02-16 09:46:45","TRT02SDTM":"2021-02-16 09:46:45","TRT02EDTM":"2022-02-16 15:46:45","AP01SDTM":"2020-07-05 21:31:45","AP01EDTM":"2021-02-16 09:46:45","AP02SDTM":"2021-02-16 09:46:45","AP02EDTM":"2022-02-16 15:46:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":591,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-05","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":149,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97626,"AVALU":"g/L","BASE2":2.82416,"BASE":2.97626,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.1521,"PCHG2":5.38561,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-13 21:31:45","ADY":70,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-140","SUBJID":"id-140","SITEID":"USA-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":14.22993,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-03","TRTSDTM":"2020-07-05 21:31:45","TRTEDTM":"2022-02-16 15:46:45","TRT01SDTM":"2020-07-05 21:31:45","TRT01EDTM":"2021-02-16 09:46:45","TRT02SDTM":"2021-02-16 09:46:45","TRT02EDTM":"2022-02-16 15:46:45","AP01SDTM":"2020-07-05 21:31:45","AP01EDTM":"2021-02-16 09:46:45","AP02SDTM":"2021-02-16 09:46:45","AP02EDTM":"2022-02-16 15:46:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":591,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-05","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3521,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82569,"AVALU":"g/L","BASE2":2.82416,"BASE":2.97626,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00152,"PCHG2":0.05388,"CHG":-0.15058,"PCHG":-5.05926,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-07 21:31:45","ADY":186,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-140","SUBJID":"id-140","SITEID":"USA-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":14.22993,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-03","TRTSDTM":"2020-07-05 21:31:45","TRTEDTM":"2022-02-16 15:46:45","TRT01SDTM":"2020-07-05 21:31:45","TRT01EDTM":"2021-02-16 09:46:45","TRT02SDTM":"2021-02-16 09:46:45","TRT02EDTM":"2022-02-16 15:46:45","AP01SDTM":"2020-07-05 21:31:45","AP01EDTM":"2021-02-16 09:46:45","AP02SDTM":"2021-02-16 09:46:45","AP02EDTM":"2022-02-16 15:46:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":591,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-05","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":157,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75507,"AVALU":"g/L","BASE2":2.82416,"BASE":2.97626,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0691,"PCHG2":-2.44663,"CHG":-0.2212,"PCHG":-7.43198,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-29 21:31:45","ADY":328,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-140","SUBJID":"id-140","SITEID":"USA-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":14.22993,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-03","TRTSDTM":"2020-07-05 21:31:45","TRTEDTM":"2022-02-16 15:46:45","TRT01SDTM":"2020-07-05 21:31:45","TRT01EDTM":"2021-02-16 09:46:45","TRT02SDTM":"2021-02-16 09:46:45","TRT02EDTM":"2022-02-16 15:46:45","AP01SDTM":"2020-07-05 21:31:45","AP01EDTM":"2021-02-16 09:46:45","AP02SDTM":"2021-02-16 09:46:45","AP02EDTM":"2022-02-16 15:46:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":591,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-05","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6050,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80658,"AVALU":"g/L","BASE2":2.82416,"BASE":2.97626,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01759,"PCHG2":-0.62273,"CHG":-0.16969,"PCHG":-5.70129,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-04 21:31:45","ADY":334,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-140","SUBJID":"id-140","SITEID":"USA-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":14.22993,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-03","TRTSDTM":"2020-07-05 21:31:45","TRTEDTM":"2022-02-16 15:46:45","TRT01SDTM":"2020-07-05 21:31:45","TRT01EDTM":"2021-02-16 09:46:45","TRT02SDTM":"2021-02-16 09:46:45","TRT02EDTM":"2022-02-16 15:46:45","AP01SDTM":"2020-07-05 21:31:45","AP01EDTM":"2021-02-16 09:46:45","AP02SDTM":"2021-02-16 09:46:45","AP02EDTM":"2022-02-16 15:46:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":591,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-05","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5272,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93701,"AVALU":"g/L","BASE2":2.82416,"BASE":2.97626,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.11284,"PCHG2":3.99559,"CHG":-0.03926,"PCHG":-1.31899,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-14 21:31:45","ADY":436,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-140","SUBJID":"id-140","SITEID":"USA-12","AGE":32,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":14.22993,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-03","TRTSDTM":"2020-07-05 21:31:45","TRTEDTM":"2022-02-16 15:46:45","TRT01SDTM":"2020-07-05 21:31:45","TRT01EDTM":"2021-02-16 09:46:45","TRT02SDTM":"2021-02-16 09:46:45","TRT02EDTM":"2022-02-16 15:46:45","AP01SDTM":"2020-07-05 21:31:45","AP01EDTM":"2021-02-16 09:46:45","AP02SDTM":"2021-02-16 09:46:45","AP02EDTM":"2022-02-16 15:46:45","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-16","EOSDY":591,"DCSREAS":"PROTOCOL VIOLATION","LSTALVDT":"2022-03-05","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5057,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87554,"AVALU":"g/L","BASE2":2.82416,"BASE":2.97626,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05137,"PCHG2":1.81909,"CHG":-0.10072,"PCHG":-3.38426,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-16 21:31:45","ADY":499,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-152","SUBJID":"id-152","SITEID":"USA-12","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.7299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 08:35:43","TRTEDTM":"2023-08-18 02:35:43","TRT01SDTM":"2020-08-17 08:35:43","TRT01EDTM":"2022-08-17 20:35:43","TRT02SDTM":"2022-08-17 20:35:43","TRT02EDTM":"2023-08-18 02:35:43","AP01SDTM":"2020-08-17 08:35:43","AP01EDTM":"2022-08-17 20:35:43","AP02SDTM":"2022-08-17 20:35:43","AP02EDTM":"2023-08-18 02:35:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-14","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3929,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.49434,"AVALU":"U/L","BASE2":17.49434,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-12-19 08:35:43","ADY":124,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-152","SUBJID":"id-152","SITEID":"USA-12","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.7299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 08:35:43","TRTEDTM":"2023-08-18 02:35:43","TRT01SDTM":"2020-08-17 08:35:43","TRT01EDTM":"2022-08-17 20:35:43","TRT02SDTM":"2022-08-17 20:35:43","TRT02EDTM":"2023-08-18 02:35:43","AP01SDTM":"2020-08-17 08:35:43","AP01EDTM":"2022-08-17 20:35:43","AP02SDTM":"2022-08-17 20:35:43","AP02EDTM":"2023-08-18 02:35:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-14","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5835,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.56302,"AVALU":"U/L","BASE2":17.49434,"BASE":5.56302,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-11.93132,"PCHG2":-68.20101,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2021-01-21 08:35:43","ADY":157,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-152","SUBJID":"id-152","SITEID":"USA-12","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.7299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 08:35:43","TRTEDTM":"2023-08-18 02:35:43","TRT01SDTM":"2020-08-17 08:35:43","TRT01EDTM":"2022-08-17 20:35:43","TRT02SDTM":"2022-08-17 20:35:43","TRT02EDTM":"2023-08-18 02:35:43","AP01SDTM":"2020-08-17 08:35:43","AP01EDTM":"2022-08-17 20:35:43","AP02SDTM":"2022-08-17 20:35:43","AP02EDTM":"2023-08-18 02:35:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-14","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1375,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.59657,"AVALU":"U/L","BASE2":17.49434,"BASE":5.56302,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":15.10223,"PCHG2":86.32634,"CHG":27.03354,"PCHG":485.95053,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-03-09 08:35:43","ADY":204,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-152","SUBJID":"id-152","SITEID":"USA-12","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.7299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 08:35:43","TRTEDTM":"2023-08-18 02:35:43","TRT01SDTM":"2020-08-17 08:35:43","TRT01EDTM":"2022-08-17 20:35:43","TRT02SDTM":"2022-08-17 20:35:43","TRT02EDTM":"2023-08-18 02:35:43","AP01SDTM":"2020-08-17 08:35:43","AP01EDTM":"2022-08-17 20:35:43","AP02SDTM":"2022-08-17 20:35:43","AP02EDTM":"2023-08-18 02:35:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-14","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5765,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.97478,"AVALU":"U/L","BASE2":17.49434,"BASE":5.56302,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.51956,"PCHG2":-8.686,"CHG":10.41176,"PCHG":187.16007,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-07-19 08:35:43","ADY":336,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-152","SUBJID":"id-152","SITEID":"USA-12","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.7299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 08:35:43","TRTEDTM":"2023-08-18 02:35:43","TRT01SDTM":"2020-08-17 08:35:43","TRT01EDTM":"2022-08-17 20:35:43","TRT02SDTM":"2022-08-17 20:35:43","TRT02EDTM":"2023-08-18 02:35:43","AP01SDTM":"2020-08-17 08:35:43","AP01EDTM":"2022-08-17 20:35:43","AP02SDTM":"2022-08-17 20:35:43","AP02EDTM":"2023-08-18 02:35:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-14","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6976,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.36585,"AVALU":"U/L","BASE2":17.49434,"BASE":5.56302,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.87151,"PCHG2":67.85914,"CHG":23.80283,"PCHG":427.87573,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-09-15 08:35:43","ADY":394,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-152","SUBJID":"id-152","SITEID":"USA-12","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.7299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 08:35:43","TRTEDTM":"2023-08-18 02:35:43","TRT01SDTM":"2020-08-17 08:35:43","TRT01EDTM":"2022-08-17 20:35:43","TRT02SDTM":"2022-08-17 20:35:43","TRT02EDTM":"2023-08-18 02:35:43","AP01SDTM":"2020-08-17 08:35:43","AP01EDTM":"2022-08-17 20:35:43","AP02SDTM":"2022-08-17 20:35:43","AP02EDTM":"2023-08-18 02:35:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-14","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5590,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.62145,"AVALU":"U/L","BASE2":17.49434,"BASE":5.56302,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.12711,"PCHG2":63.60405,"CHG":23.05843,"PCHG":414.49454,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2023-05-26 08:35:43","ADY":1012,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-152","SUBJID":"id-152","SITEID":"USA-12","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.7299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 08:35:43","TRTEDTM":"2023-08-18 02:35:43","TRT01SDTM":"2020-08-17 08:35:43","TRT01EDTM":"2022-08-17 20:35:43","TRT02SDTM":"2022-08-17 20:35:43","TRT02EDTM":"2023-08-18 02:35:43","AP01SDTM":"2020-08-17 08:35:43","AP01EDTM":"2022-08-17 20:35:43","AP02SDTM":"2022-08-17 20:35:43","AP02EDTM":"2023-08-18 02:35:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-14","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1961,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.95632,"AVALU":"U/L","BASE2":17.49434,"BASE":5.56302,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.46198,"PCHG2":25.50525,"CHG":16.39329,"PCHG":294.68315,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2023-07-02 08:35:43","ADY":1049,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-152","SUBJID":"id-152","SITEID":"USA-12","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.7299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 08:35:43","TRTEDTM":"2023-08-18 02:35:43","TRT01SDTM":"2020-08-17 08:35:43","TRT01EDTM":"2022-08-17 20:35:43","TRT02SDTM":"2022-08-17 20:35:43","TRT02EDTM":"2023-08-18 02:35:43","AP01SDTM":"2020-08-17 08:35:43","AP01EDTM":"2022-08-17 20:35:43","AP02SDTM":"2022-08-17 20:35:43","AP02EDTM":"2023-08-18 02:35:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-14","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4388,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.30279,"AVALU":"mg/L","BASE2":9.30279,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-19 08:35:43","ADY":124,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-152","SUBJID":"id-152","SITEID":"USA-12","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.7299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 08:35:43","TRTEDTM":"2023-08-18 02:35:43","TRT01SDTM":"2020-08-17 08:35:43","TRT01EDTM":"2022-08-17 20:35:43","TRT02SDTM":"2022-08-17 20:35:43","TRT02EDTM":"2023-08-18 02:35:43","AP01SDTM":"2020-08-17 08:35:43","AP01EDTM":"2022-08-17 20:35:43","AP02SDTM":"2022-08-17 20:35:43","AP02EDTM":"2023-08-18 02:35:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-14","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5795,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.82421,"AVALU":"mg/L","BASE2":9.30279,"BASE":9.82421,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.52143,"PCHG2":5.60506,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-21 08:35:43","ADY":157,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-152","SUBJID":"id-152","SITEID":"USA-12","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.7299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 08:35:43","TRTEDTM":"2023-08-18 02:35:43","TRT01SDTM":"2020-08-17 08:35:43","TRT01EDTM":"2022-08-17 20:35:43","TRT02SDTM":"2022-08-17 20:35:43","TRT02EDTM":"2023-08-18 02:35:43","AP01SDTM":"2020-08-17 08:35:43","AP01EDTM":"2022-08-17 20:35:43","AP02SDTM":"2022-08-17 20:35:43","AP02EDTM":"2023-08-18 02:35:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-14","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6494,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.37738,"AVALU":"mg/L","BASE2":9.30279,"BASE":9.82421,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07459,"PCHG2":0.8018,"CHG":-0.44684,"PCHG":-4.54832,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-09 08:35:43","ADY":204,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-152","SUBJID":"id-152","SITEID":"USA-12","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.7299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 08:35:43","TRTEDTM":"2023-08-18 02:35:43","TRT01SDTM":"2020-08-17 08:35:43","TRT01EDTM":"2022-08-17 20:35:43","TRT02SDTM":"2022-08-17 20:35:43","TRT02EDTM":"2023-08-18 02:35:43","AP01SDTM":"2020-08-17 08:35:43","AP01EDTM":"2022-08-17 20:35:43","AP02SDTM":"2022-08-17 20:35:43","AP02EDTM":"2023-08-18 02:35:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-14","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":906,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.13721,"AVALU":"mg/L","BASE2":9.30279,"BASE":9.82421,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.83443,"PCHG2":8.96965,"CHG":0.313,"PCHG":3.18602,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-07-19 08:35:43","ADY":336,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-152","SUBJID":"id-152","SITEID":"USA-12","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.7299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 08:35:43","TRTEDTM":"2023-08-18 02:35:43","TRT01SDTM":"2020-08-17 08:35:43","TRT01EDTM":"2022-08-17 20:35:43","TRT02SDTM":"2022-08-17 20:35:43","TRT02EDTM":"2023-08-18 02:35:43","AP01SDTM":"2020-08-17 08:35:43","AP01EDTM":"2022-08-17 20:35:43","AP02SDTM":"2022-08-17 20:35:43","AP02EDTM":"2023-08-18 02:35:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-14","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":148,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.08,"AVALU":"mg/L","BASE2":9.30279,"BASE":9.82421,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.22279,"PCHG2":-13.14431,"CHG":-1.74421,"PCHG":-17.75423,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-15 08:35:43","ADY":394,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-152","SUBJID":"id-152","SITEID":"USA-12","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.7299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 08:35:43","TRTEDTM":"2023-08-18 02:35:43","TRT01SDTM":"2020-08-17 08:35:43","TRT01EDTM":"2022-08-17 20:35:43","TRT02SDTM":"2022-08-17 20:35:43","TRT02EDTM":"2023-08-18 02:35:43","AP01SDTM":"2020-08-17 08:35:43","AP01EDTM":"2022-08-17 20:35:43","AP02SDTM":"2022-08-17 20:35:43","AP02EDTM":"2023-08-18 02:35:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-14","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3771,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.42199,"AVALU":"mg/L","BASE2":9.30279,"BASE":9.82421,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.11921,"PCHG2":12.03089,"CHG":0.59778,"PCHG":6.08478,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2023-05-26 08:35:43","ADY":1012,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-152","SUBJID":"id-152","SITEID":"USA-12","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.7299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 08:35:43","TRTEDTM":"2023-08-18 02:35:43","TRT01SDTM":"2020-08-17 08:35:43","TRT01EDTM":"2022-08-17 20:35:43","TRT02SDTM":"2022-08-17 20:35:43","TRT02EDTM":"2023-08-18 02:35:43","AP01SDTM":"2020-08-17 08:35:43","AP01EDTM":"2022-08-17 20:35:43","AP02SDTM":"2022-08-17 20:35:43","AP02EDTM":"2023-08-18 02:35:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-14","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2448,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.6613,"AVALU":"mg/L","BASE2":9.30279,"BASE":9.82421,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.35851,"PCHG2":3.85381,"CHG":-0.16291,"PCHG":-1.65829,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-02 08:35:43","ADY":1049,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-152","SUBJID":"id-152","SITEID":"USA-12","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.7299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 08:35:43","TRTEDTM":"2023-08-18 02:35:43","TRT01SDTM":"2020-08-17 08:35:43","TRT01EDTM":"2022-08-17 20:35:43","TRT02SDTM":"2022-08-17 20:35:43","TRT02EDTM":"2023-08-18 02:35:43","AP01SDTM":"2020-08-17 08:35:43","AP01EDTM":"2022-08-17 20:35:43","AP02SDTM":"2022-08-17 20:35:43","AP02EDTM":"2023-08-18 02:35:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-14","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":375,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.04576,"AVALU":"g/L","BASE2":3.04576,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-12-19 08:35:43","ADY":124,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-152","SUBJID":"id-152","SITEID":"USA-12","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.7299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 08:35:43","TRTEDTM":"2023-08-18 02:35:43","TRT01SDTM":"2020-08-17 08:35:43","TRT01EDTM":"2022-08-17 20:35:43","TRT02SDTM":"2022-08-17 20:35:43","TRT02EDTM":"2023-08-18 02:35:43","AP01SDTM":"2020-08-17 08:35:43","AP01EDTM":"2022-08-17 20:35:43","AP02SDTM":"2022-08-17 20:35:43","AP02EDTM":"2023-08-18 02:35:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-14","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8237,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86535,"AVALU":"g/L","BASE2":3.04576,"BASE":2.86535,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.18041,"PCHG2":-5.92329,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-21 08:35:43","ADY":157,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-152","SUBJID":"id-152","SITEID":"USA-12","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.7299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 08:35:43","TRTEDTM":"2023-08-18 02:35:43","TRT01SDTM":"2020-08-17 08:35:43","TRT01EDTM":"2022-08-17 20:35:43","TRT02SDTM":"2022-08-17 20:35:43","TRT02EDTM":"2023-08-18 02:35:43","AP01SDTM":"2020-08-17 08:35:43","AP01EDTM":"2022-08-17 20:35:43","AP02SDTM":"2022-08-17 20:35:43","AP02EDTM":"2023-08-18 02:35:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-14","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8190,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.6924,"AVALU":"g/L","BASE2":3.04576,"BASE":2.86535,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.35336,"PCHG2":-11.60181,"CHG":-0.17295,"PCHG":-6.03604,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-09 08:35:43","ADY":204,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-152","SUBJID":"id-152","SITEID":"USA-12","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.7299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 08:35:43","TRTEDTM":"2023-08-18 02:35:43","TRT01SDTM":"2020-08-17 08:35:43","TRT01EDTM":"2022-08-17 20:35:43","TRT02SDTM":"2022-08-17 20:35:43","TRT02EDTM":"2023-08-18 02:35:43","AP01SDTM":"2020-08-17 08:35:43","AP01EDTM":"2022-08-17 20:35:43","AP02SDTM":"2022-08-17 20:35:43","AP02EDTM":"2023-08-18 02:35:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-14","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3847,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92075,"AVALU":"g/L","BASE2":3.04576,"BASE":2.86535,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.12501,"PCHG2":-4.10437,"CHG":0.0554,"PCHG":1.93345,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-19 08:35:43","ADY":336,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-152","SUBJID":"id-152","SITEID":"USA-12","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.7299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 08:35:43","TRTEDTM":"2023-08-18 02:35:43","TRT01SDTM":"2020-08-17 08:35:43","TRT01EDTM":"2022-08-17 20:35:43","TRT02SDTM":"2022-08-17 20:35:43","TRT02EDTM":"2023-08-18 02:35:43","AP01SDTM":"2020-08-17 08:35:43","AP01EDTM":"2022-08-17 20:35:43","AP02SDTM":"2022-08-17 20:35:43","AP02EDTM":"2023-08-18 02:35:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-14","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4058,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9442,"AVALU":"g/L","BASE2":3.04576,"BASE":2.86535,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10156,"PCHG2":-3.33447,"CHG":0.07885,"PCHG":2.75182,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-15 08:35:43","ADY":394,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-152","SUBJID":"id-152","SITEID":"USA-12","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.7299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 08:35:43","TRTEDTM":"2023-08-18 02:35:43","TRT01SDTM":"2020-08-17 08:35:43","TRT01EDTM":"2022-08-17 20:35:43","TRT02SDTM":"2022-08-17 20:35:43","TRT02EDTM":"2023-08-18 02:35:43","AP01SDTM":"2020-08-17 08:35:43","AP01EDTM":"2022-08-17 20:35:43","AP02SDTM":"2022-08-17 20:35:43","AP02EDTM":"2023-08-18 02:35:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-14","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":268,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95269,"AVALU":"g/L","BASE2":3.04576,"BASE":2.86535,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09307,"PCHG2":-3.05571,"CHG":0.08734,"PCHG":3.04813,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-05-26 08:35:43","ADY":1012,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-152","SUBJID":"id-152","SITEID":"USA-12","AGE":29,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":6.7299,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-08-14","TRTSDTM":"2020-08-17 08:35:43","TRTEDTM":"2023-08-18 02:35:43","TRT01SDTM":"2020-08-17 08:35:43","TRT01EDTM":"2022-08-17 20:35:43","TRT02SDTM":"2022-08-17 20:35:43","TRT02EDTM":"2023-08-18 02:35:43","AP01SDTM":"2020-08-17 08:35:43","AP01EDTM":"2022-08-17 20:35:43","AP02SDTM":"2022-08-17 20:35:43","AP02EDTM":"2023-08-18 02:35:43","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-08-18","EOSDY":1096,"LSTALVDT":"2023-09-14","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5761,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98632,"AVALU":"g/L","BASE2":3.04576,"BASE":2.86535,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05944,"PCHG2":-1.95167,"CHG":0.12097,"PCHG":4.22169,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-07-02 08:35:43","ADY":1049,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-226","SUBJID":"id-226","SITEID":"USA-12","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":4.21439,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-25","TRTSDTM":"2020-01-29 18:22:03","TRT01SDTM":"2020-01-29 18:22:03","AP01SDTM":"2020-01-29 18:22:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3727,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.30373,"AVALU":"U/L","BASE2":26.30373,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-17 18:22:03","ADY":79,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-226","SUBJID":"id-226","SITEID":"USA-12","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":4.21439,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-25","TRTSDTM":"2020-01-29 18:22:03","TRT01SDTM":"2020-01-29 18:22:03","AP01SDTM":"2020-01-29 18:22:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4687,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.33041,"AVALU":"U/L","BASE2":26.30373,"BASE":26.33041,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.02668,"PCHG2":0.10143,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-04 18:22:03","ADY":96,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-226","SUBJID":"id-226","SITEID":"USA-12","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":4.21439,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-25","TRTSDTM":"2020-01-29 18:22:03","TRT01SDTM":"2020-01-29 18:22:03","AP01SDTM":"2020-01-29 18:22:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3083,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.74934,"AVALU":"U/L","BASE2":26.30373,"BASE":26.33041,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.55439,"PCHG2":-40.12507,"CHG":-10.58107,"PCHG":-40.18574,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-08 18:22:03","ADY":314,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-226","SUBJID":"id-226","SITEID":"USA-12","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":4.21439,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-25","TRTSDTM":"2020-01-29 18:22:03","TRT01SDTM":"2020-01-29 18:22:03","AP01SDTM":"2020-01-29 18:22:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3179,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.1701,"AVALU":"U/L","BASE2":26.30373,"BASE":26.33041,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.13363,"PCHG2":-8.11151,"CHG":-2.16031,"PCHG":-8.20462,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-16 18:22:03","ADY":322,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-226","SUBJID":"id-226","SITEID":"USA-12","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":4.21439,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-25","TRTSDTM":"2020-01-29 18:22:03","TRT01SDTM":"2020-01-29 18:22:03","AP01SDTM":"2020-01-29 18:22:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7369,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.02358,"AVALU":"U/L","BASE2":26.30373,"BASE":26.33041,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-26.28015,"PCHG2":-99.91036,"CHG":-26.30683,"PCHG":-99.91045,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-08-09 18:22:03","ADY":558,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-226","SUBJID":"id-226","SITEID":"USA-12","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":4.21439,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-25","TRTSDTM":"2020-01-29 18:22:03","TRT01SDTM":"2020-01-29 18:22:03","AP01SDTM":"2020-01-29 18:22:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3477,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.10661,"AVALU":"U/L","BASE2":26.30373,"BASE":26.33041,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-8.19712,"PCHG2":-31.16332,"CHG":-8.2238,"PCHG":-31.23307,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-24 18:22:03","ADY":573,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-226","SUBJID":"id-226","SITEID":"USA-12","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":4.21439,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-25","TRTSDTM":"2020-01-29 18:22:03","TRT01SDTM":"2020-01-29 18:22:03","AP01SDTM":"2020-01-29 18:22:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6917,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.35782,"AVALU":"U/L","BASE2":26.30373,"BASE":26.33041,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.94591,"PCHG2":-30.20831,"CHG":-7.97259,"PCHG":-30.27903,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-22 18:22:03","ADY":602,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-226","SUBJID":"id-226","SITEID":"USA-12","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":4.21439,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-25","TRTSDTM":"2020-01-29 18:22:03","TRT01SDTM":"2020-01-29 18:22:03","AP01SDTM":"2020-01-29 18:22:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":151,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.14548,"AVALU":"mg/L","BASE2":9.14548,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-17 18:22:03","ADY":79,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-226","SUBJID":"id-226","SITEID":"USA-12","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":4.21439,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-25","TRTSDTM":"2020-01-29 18:22:03","TRT01SDTM":"2020-01-29 18:22:03","AP01SDTM":"2020-01-29 18:22:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4609,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.75357,"AVALU":"mg/L","BASE2":9.14548,"BASE":8.75357,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.39191,"PCHG2":-4.28525,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-04 18:22:03","ADY":96,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-226","SUBJID":"id-226","SITEID":"USA-12","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":4.21439,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-25","TRTSDTM":"2020-01-29 18:22:03","TRT01SDTM":"2020-01-29 18:22:03","AP01SDTM":"2020-01-29 18:22:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6421,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.26704,"AVALU":"mg/L","BASE2":9.14548,"BASE":8.75357,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.87844,"PCHG2":-9.60515,"CHG":-0.48653,"PCHG":-5.55808,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-08 18:22:03","ADY":314,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-226","SUBJID":"id-226","SITEID":"USA-12","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":4.21439,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-25","TRTSDTM":"2020-01-29 18:22:03","TRT01SDTM":"2020-01-29 18:22:03","AP01SDTM":"2020-01-29 18:22:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2025,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.18551,"AVALU":"mg/L","BASE2":9.14548,"BASE":8.75357,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.95997,"PCHG2":-10.49665,"CHG":-0.56806,"PCHG":-6.48949,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-16 18:22:03","ADY":322,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-226","SUBJID":"id-226","SITEID":"USA-12","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":4.21439,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-25","TRTSDTM":"2020-01-29 18:22:03","TRT01SDTM":"2020-01-29 18:22:03","AP01SDTM":"2020-01-29 18:22:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5529,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.31519,"AVALU":"mg/L","BASE2":9.14548,"BASE":8.75357,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.16972,"PCHG2":1.85574,"CHG":0.56162,"PCHG":6.41593,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-09 18:22:03","ADY":558,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-226","SUBJID":"id-226","SITEID":"USA-12","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":4.21439,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-25","TRTSDTM":"2020-01-29 18:22:03","TRT01SDTM":"2020-01-29 18:22:03","AP01SDTM":"2020-01-29 18:22:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":139,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.61957,"AVALU":"mg/L","BASE2":9.14548,"BASE":8.75357,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.47409,"PCHG2":16.11823,"CHG":1.866,"PCHG":21.31697,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-08-24 18:22:03","ADY":573,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-226","SUBJID":"id-226","SITEID":"USA-12","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":4.21439,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-25","TRTSDTM":"2020-01-29 18:22:03","TRT01SDTM":"2020-01-29 18:22:03","AP01SDTM":"2020-01-29 18:22:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3886,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.53008,"AVALU":"mg/L","BASE2":9.14548,"BASE":8.75357,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.6154,"PCHG2":-17.66335,"CHG":-1.22349,"PCHG":-13.97706,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-09-22 18:22:03","ADY":602,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-226","SUBJID":"id-226","SITEID":"USA-12","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":4.21439,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-25","TRTSDTM":"2020-01-29 18:22:03","TRT01SDTM":"2020-01-29 18:22:03","AP01SDTM":"2020-01-29 18:22:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3307,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88089,"AVALU":"g/L","BASE2":2.88089,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-04-17 18:22:03","ADY":79,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-226","SUBJID":"id-226","SITEID":"USA-12","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":4.21439,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-25","TRTSDTM":"2020-01-29 18:22:03","TRT01SDTM":"2020-01-29 18:22:03","AP01SDTM":"2020-01-29 18:22:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6245,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.01226,"AVALU":"g/L","BASE2":2.88089,"BASE":3.01226,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.13137,"PCHG2":4.56001,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2020-05-04 18:22:03","ADY":96,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-226","SUBJID":"id-226","SITEID":"USA-12","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":4.21439,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-25","TRTSDTM":"2020-01-29 18:22:03","TRT01SDTM":"2020-01-29 18:22:03","AP01SDTM":"2020-01-29 18:22:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4786,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87932,"AVALU":"g/L","BASE2":2.88089,"BASE":3.01226,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00157,"PCHG2":-0.05458,"CHG":-0.13294,"PCHG":-4.41334,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-12-08 18:22:03","ADY":314,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-226","SUBJID":"id-226","SITEID":"USA-12","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":4.21439,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-25","TRTSDTM":"2020-01-29 18:22:03","TRT01SDTM":"2020-01-29 18:22:03","AP01SDTM":"2020-01-29 18:22:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2897,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79319,"AVALU":"g/L","BASE2":2.88089,"BASE":3.01226,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08771,"PCHG2":-3.04437,"CHG":-0.21907,"PCHG":-7.27275,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-12-16 18:22:03","ADY":322,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-226","SUBJID":"id-226","SITEID":"USA-12","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":4.21439,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-25","TRTSDTM":"2020-01-29 18:22:03","TRT01SDTM":"2020-01-29 18:22:03","AP01SDTM":"2020-01-29 18:22:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2636,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80371,"AVALU":"g/L","BASE2":2.88089,"BASE":3.01226,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07719,"PCHG2":-2.67924,"CHG":-0.20856,"PCHG":-6.92354,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-08-09 18:22:03","ADY":558,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-226","SUBJID":"id-226","SITEID":"USA-12","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":4.21439,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-25","TRTSDTM":"2020-01-29 18:22:03","TRT01SDTM":"2020-01-29 18:22:03","AP01SDTM":"2020-01-29 18:22:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5710,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.14229,"AVALU":"g/L","BASE2":2.88089,"BASE":3.01226,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.26139,"PCHG2":9.07336,"CHG":0.13002,"PCHG":4.31651,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"2","BTOXGR":"1","ADTM":"2021-08-24 18:22:03","ADY":573,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-226","SUBJID":"id-226","SITEID":"USA-12","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":4.21439,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"Y","RANDDT":"2020-01-25","TRTSDTM":"2020-01-29 18:22:03","TRT01SDTM":"2020-01-29 18:22:03","AP01SDTM":"2020-01-29 18:22:03","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5231,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97833,"AVALU":"g/L","BASE2":2.88089,"BASE":3.01226,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.09744,"PCHG2":3.38229,"CHG":-0.03393,"PCHG":-1.12636,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-09-22 18:22:03","ADY":602,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-343","SUBJID":"id-343","SITEID":"USA-12","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.75539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-15","TRTSDTM":"2020-03-18 17:13:25","TRTEDTM":"2023-03-19 11:13:25","TRT01SDTM":"2020-03-18 17:13:25","TRT01EDTM":"2022-03-19 05:13:25","TRT02SDTM":"2022-03-19 05:13:25","TRT02EDTM":"2023-03-19 11:13:25","AP01SDTM":"2020-03-18 17:13:25","AP01EDTM":"2022-03-19 05:13:25","AP02SDTM":"2022-03-19 05:13:25","AP02EDTM":"2023-03-19 11:13:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-19","EOSDY":1096,"LSTALVDT":"2023-04-17","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4209,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":36.03142,"AVALU":"U/L","BASE2":36.03142,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-30 17:13:25","ADY":73,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-343","SUBJID":"id-343","SITEID":"USA-12","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.75539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-15","TRTSDTM":"2020-03-18 17:13:25","TRTEDTM":"2023-03-19 11:13:25","TRT01SDTM":"2020-03-18 17:13:25","TRT01EDTM":"2022-03-19 05:13:25","TRT02SDTM":"2022-03-19 05:13:25","TRT02EDTM":"2023-03-19 11:13:25","AP01SDTM":"2020-03-18 17:13:25","AP01EDTM":"2022-03-19 05:13:25","AP02SDTM":"2022-03-19 05:13:25","AP02EDTM":"2023-03-19 11:13:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-19","EOSDY":1096,"LSTALVDT":"2023-04-17","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1778,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.80331,"AVALU":"U/L","BASE2":36.03142,"BASE":15.80331,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-20.22811,"PCHG2":-56.14019,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-09 17:13:25","ADY":144,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-343","SUBJID":"id-343","SITEID":"USA-12","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.75539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-15","TRTSDTM":"2020-03-18 17:13:25","TRTEDTM":"2023-03-19 11:13:25","TRT01SDTM":"2020-03-18 17:13:25","TRT01EDTM":"2022-03-19 05:13:25","TRT02SDTM":"2022-03-19 05:13:25","TRT02EDTM":"2023-03-19 11:13:25","AP01SDTM":"2020-03-18 17:13:25","AP01EDTM":"2022-03-19 05:13:25","AP02SDTM":"2022-03-19 05:13:25","AP02EDTM":"2023-03-19 11:13:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-19","EOSDY":1096,"LSTALVDT":"2023-04-17","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3495,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.80038,"AVALU":"U/L","BASE2":36.03142,"BASE":15.80331,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.23104,"PCHG2":-20.0687,"CHG":12.99707,"PCHG":82.24268,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-07 17:13:25","ADY":234,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-343","SUBJID":"id-343","SITEID":"USA-12","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.75539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-15","TRTSDTM":"2020-03-18 17:13:25","TRTEDTM":"2023-03-19 11:13:25","TRT01SDTM":"2020-03-18 17:13:25","TRT01EDTM":"2022-03-19 05:13:25","TRT02SDTM":"2022-03-19 05:13:25","TRT02EDTM":"2023-03-19 11:13:25","AP01SDTM":"2020-03-18 17:13:25","AP01EDTM":"2022-03-19 05:13:25","AP02SDTM":"2022-03-19 05:13:25","AP02EDTM":"2023-03-19 11:13:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-19","EOSDY":1096,"LSTALVDT":"2023-04-17","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8098,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.90585,"AVALU":"U/L","BASE2":36.03142,"BASE":15.80331,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.12557,"PCHG2":-14.22528,"CHG":15.10254,"PCHG":95.56563,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-05 17:13:25","ADY":566,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-343","SUBJID":"id-343","SITEID":"USA-12","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.75539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-15","TRTSDTM":"2020-03-18 17:13:25","TRTEDTM":"2023-03-19 11:13:25","TRT01SDTM":"2020-03-18 17:13:25","TRT01EDTM":"2022-03-19 05:13:25","TRT02SDTM":"2022-03-19 05:13:25","TRT02EDTM":"2023-03-19 11:13:25","AP01SDTM":"2020-03-18 17:13:25","AP01EDTM":"2022-03-19 05:13:25","AP02SDTM":"2022-03-19 05:13:25","AP02EDTM":"2023-03-19 11:13:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-19","EOSDY":1096,"LSTALVDT":"2023-04-17","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4615,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.56316,"AVALU":"U/L","BASE2":36.03142,"BASE":15.80331,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-32.46826,"PCHG2":-90.11096,"CHG":-12.24015,"PCHG":-77.45308,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-10-06 17:13:25","ADY":567,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-343","SUBJID":"id-343","SITEID":"USA-12","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.75539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-15","TRTSDTM":"2020-03-18 17:13:25","TRTEDTM":"2023-03-19 11:13:25","TRT01SDTM":"2020-03-18 17:13:25","TRT01EDTM":"2022-03-19 05:13:25","TRT02SDTM":"2022-03-19 05:13:25","TRT02EDTM":"2023-03-19 11:13:25","AP01SDTM":"2020-03-18 17:13:25","AP01EDTM":"2022-03-19 05:13:25","AP02SDTM":"2022-03-19 05:13:25","AP02EDTM":"2023-03-19 11:13:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-19","EOSDY":1096,"LSTALVDT":"2023-04-17","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5097,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.79107,"AVALU":"U/L","BASE2":36.03142,"BASE":15.80331,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-15.24035,"PCHG2":-42.29739,"CHG":4.98776,"PCHG":31.56146,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-26 17:13:25","ADY":922,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-343","SUBJID":"id-343","SITEID":"USA-12","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.75539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-15","TRTSDTM":"2020-03-18 17:13:25","TRTEDTM":"2023-03-19 11:13:25","TRT01SDTM":"2020-03-18 17:13:25","TRT01EDTM":"2022-03-19 05:13:25","TRT02SDTM":"2022-03-19 05:13:25","TRT02EDTM":"2023-03-19 11:13:25","AP01SDTM":"2020-03-18 17:13:25","AP01EDTM":"2022-03-19 05:13:25","AP02SDTM":"2022-03-19 05:13:25","AP02EDTM":"2023-03-19 11:13:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-19","EOSDY":1096,"LSTALVDT":"2023-04-17","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5124,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.5806,"AVALU":"U/L","BASE2":36.03142,"BASE":15.80331,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-30.45082,"PCHG2":-84.51186,"CHG":-10.22272,"PCHG":-64.68717,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2023-02-28 17:13:25","ADY":1077,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-343","SUBJID":"id-343","SITEID":"USA-12","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.75539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-15","TRTSDTM":"2020-03-18 17:13:25","TRTEDTM":"2023-03-19 11:13:25","TRT01SDTM":"2020-03-18 17:13:25","TRT01EDTM":"2022-03-19 05:13:25","TRT02SDTM":"2022-03-19 05:13:25","TRT02EDTM":"2023-03-19 11:13:25","AP01SDTM":"2020-03-18 17:13:25","AP01EDTM":"2022-03-19 05:13:25","AP02SDTM":"2022-03-19 05:13:25","AP02EDTM":"2023-03-19 11:13:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-19","EOSDY":1096,"LSTALVDT":"2023-04-17","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6151,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.05658,"AVALU":"mg/L","BASE2":9.05658,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-30 17:13:25","ADY":73,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-343","SUBJID":"id-343","SITEID":"USA-12","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.75539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-15","TRTSDTM":"2020-03-18 17:13:25","TRTEDTM":"2023-03-19 11:13:25","TRT01SDTM":"2020-03-18 17:13:25","TRT01EDTM":"2022-03-19 05:13:25","TRT02SDTM":"2022-03-19 05:13:25","TRT02EDTM":"2023-03-19 11:13:25","AP01SDTM":"2020-03-18 17:13:25","AP01EDTM":"2022-03-19 05:13:25","AP02SDTM":"2022-03-19 05:13:25","AP02EDTM":"2023-03-19 11:13:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-19","EOSDY":1096,"LSTALVDT":"2023-04-17","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1442,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.83261,"AVALU":"mg/L","BASE2":9.05658,"BASE":8.83261,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.22397,"PCHG2":-2.47305,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-09 17:13:25","ADY":144,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-343","SUBJID":"id-343","SITEID":"USA-12","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.75539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-15","TRTSDTM":"2020-03-18 17:13:25","TRTEDTM":"2023-03-19 11:13:25","TRT01SDTM":"2020-03-18 17:13:25","TRT01EDTM":"2022-03-19 05:13:25","TRT02SDTM":"2022-03-19 05:13:25","TRT02EDTM":"2023-03-19 11:13:25","AP01SDTM":"2020-03-18 17:13:25","AP01EDTM":"2022-03-19 05:13:25","AP02SDTM":"2022-03-19 05:13:25","AP02EDTM":"2023-03-19 11:13:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-19","EOSDY":1096,"LSTALVDT":"2023-04-17","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5282,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.8373,"AVALU":"mg/L","BASE2":9.05658,"BASE":8.83261,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21928,"PCHG2":-2.42126,"CHG":0.00469,"PCHG":0.05311,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-07 17:13:25","ADY":234,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-343","SUBJID":"id-343","SITEID":"USA-12","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.75539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-15","TRTSDTM":"2020-03-18 17:13:25","TRTEDTM":"2023-03-19 11:13:25","TRT01SDTM":"2020-03-18 17:13:25","TRT01EDTM":"2022-03-19 05:13:25","TRT02SDTM":"2022-03-19 05:13:25","TRT02EDTM":"2023-03-19 11:13:25","AP01SDTM":"2020-03-18 17:13:25","AP01EDTM":"2022-03-19 05:13:25","AP02SDTM":"2022-03-19 05:13:25","AP02EDTM":"2023-03-19 11:13:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-19","EOSDY":1096,"LSTALVDT":"2023-04-17","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4327,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.07424,"AVALU":"mg/L","BASE2":9.05658,"BASE":8.83261,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01765,"PCHG2":0.19493,"CHG":0.24163,"PCHG":2.73564,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-05 17:13:25","ADY":566,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-343","SUBJID":"id-343","SITEID":"USA-12","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.75539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-15","TRTSDTM":"2020-03-18 17:13:25","TRTEDTM":"2023-03-19 11:13:25","TRT01SDTM":"2020-03-18 17:13:25","TRT01EDTM":"2022-03-19 05:13:25","TRT02SDTM":"2022-03-19 05:13:25","TRT02EDTM":"2023-03-19 11:13:25","AP01SDTM":"2020-03-18 17:13:25","AP01EDTM":"2022-03-19 05:13:25","AP02SDTM":"2022-03-19 05:13:25","AP02EDTM":"2023-03-19 11:13:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-19","EOSDY":1096,"LSTALVDT":"2023-04-17","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2427,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.2993,"AVALU":"mg/L","BASE2":9.05658,"BASE":8.83261,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.75729,"PCHG2":-30.44513,"CHG":-2.53331,"PCHG":-28.68139,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-10-06 17:13:25","ADY":567,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-343","SUBJID":"id-343","SITEID":"USA-12","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.75539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-15","TRTSDTM":"2020-03-18 17:13:25","TRTEDTM":"2023-03-19 11:13:25","TRT01SDTM":"2020-03-18 17:13:25","TRT01EDTM":"2022-03-19 05:13:25","TRT02SDTM":"2022-03-19 05:13:25","TRT02EDTM":"2023-03-19 11:13:25","AP01SDTM":"2020-03-18 17:13:25","AP01EDTM":"2022-03-19 05:13:25","AP02SDTM":"2022-03-19 05:13:25","AP02EDTM":"2023-03-19 11:13:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-19","EOSDY":1096,"LSTALVDT":"2023-04-17","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7431,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.92029,"AVALU":"mg/L","BASE2":9.05658,"BASE":8.83261,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.13629,"PCHG2":-12.54658,"CHG":-0.91232,"PCHG":-10.32897,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-09-26 17:13:25","ADY":922,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-343","SUBJID":"id-343","SITEID":"USA-12","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.75539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-15","TRTSDTM":"2020-03-18 17:13:25","TRTEDTM":"2023-03-19 11:13:25","TRT01SDTM":"2020-03-18 17:13:25","TRT01EDTM":"2022-03-19 05:13:25","TRT02SDTM":"2022-03-19 05:13:25","TRT02EDTM":"2023-03-19 11:13:25","AP01SDTM":"2020-03-18 17:13:25","AP01EDTM":"2022-03-19 05:13:25","AP02SDTM":"2022-03-19 05:13:25","AP02EDTM":"2023-03-19 11:13:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-19","EOSDY":1096,"LSTALVDT":"2023-04-17","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7695,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.91979,"AVALU":"mg/L","BASE2":9.05658,"BASE":8.83261,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.1368,"PCHG2":-1.51046,"CHG":0.08718,"PCHG":0.987,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-28 17:13:25","ADY":1077,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-343","SUBJID":"id-343","SITEID":"USA-12","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.75539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-15","TRTSDTM":"2020-03-18 17:13:25","TRTEDTM":"2023-03-19 11:13:25","TRT01SDTM":"2020-03-18 17:13:25","TRT01EDTM":"2022-03-19 05:13:25","TRT02SDTM":"2022-03-19 05:13:25","TRT02EDTM":"2023-03-19 11:13:25","AP01SDTM":"2020-03-18 17:13:25","AP01EDTM":"2022-03-19 05:13:25","AP02SDTM":"2022-03-19 05:13:25","AP02EDTM":"2023-03-19 11:13:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-19","EOSDY":1096,"LSTALVDT":"2023-04-17","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":32,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.91847,"AVALU":"g/L","BASE2":2.91847,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-30 17:13:25","ADY":73,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-343","SUBJID":"id-343","SITEID":"USA-12","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.75539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-15","TRTSDTM":"2020-03-18 17:13:25","TRTEDTM":"2023-03-19 11:13:25","TRT01SDTM":"2020-03-18 17:13:25","TRT01EDTM":"2022-03-19 05:13:25","TRT02SDTM":"2022-03-19 05:13:25","TRT02EDTM":"2023-03-19 11:13:25","AP01SDTM":"2020-03-18 17:13:25","AP01EDTM":"2022-03-19 05:13:25","AP02SDTM":"2022-03-19 05:13:25","AP02EDTM":"2023-03-19 11:13:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-19","EOSDY":1096,"LSTALVDT":"2023-04-17","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4968,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8044,"AVALU":"g/L","BASE2":2.91847,"BASE":2.8044,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.11407,"PCHG2":-3.90854,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-09 17:13:25","ADY":144,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-343","SUBJID":"id-343","SITEID":"USA-12","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.75539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-15","TRTSDTM":"2020-03-18 17:13:25","TRTEDTM":"2023-03-19 11:13:25","TRT01SDTM":"2020-03-18 17:13:25","TRT01EDTM":"2022-03-19 05:13:25","TRT02SDTM":"2022-03-19 05:13:25","TRT02EDTM":"2023-03-19 11:13:25","AP01SDTM":"2020-03-18 17:13:25","AP01EDTM":"2022-03-19 05:13:25","AP02SDTM":"2022-03-19 05:13:25","AP02EDTM":"2023-03-19 11:13:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-19","EOSDY":1096,"LSTALVDT":"2023-04-17","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8380,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93791,"AVALU":"g/L","BASE2":2.91847,"BASE":2.8044,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01943,"PCHG2":0.66589,"CHG":0.1335,"PCHG":4.76049,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-07 17:13:25","ADY":234,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-343","SUBJID":"id-343","SITEID":"USA-12","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.75539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-15","TRTSDTM":"2020-03-18 17:13:25","TRTEDTM":"2023-03-19 11:13:25","TRT01SDTM":"2020-03-18 17:13:25","TRT01EDTM":"2022-03-19 05:13:25","TRT02SDTM":"2022-03-19 05:13:25","TRT02EDTM":"2023-03-19 11:13:25","AP01SDTM":"2020-03-18 17:13:25","AP01EDTM":"2022-03-19 05:13:25","AP02SDTM":"2022-03-19 05:13:25","AP02EDTM":"2023-03-19 11:13:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-19","EOSDY":1096,"LSTALVDT":"2023-04-17","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2631,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93255,"AVALU":"g/L","BASE2":2.91847,"BASE":2.8044,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01407,"PCHG2":0.48221,"CHG":0.12814,"PCHG":4.56934,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-05 17:13:25","ADY":566,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-343","SUBJID":"id-343","SITEID":"USA-12","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.75539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-15","TRTSDTM":"2020-03-18 17:13:25","TRTEDTM":"2023-03-19 11:13:25","TRT01SDTM":"2020-03-18 17:13:25","TRT01EDTM":"2022-03-19 05:13:25","TRT02SDTM":"2022-03-19 05:13:25","TRT02EDTM":"2023-03-19 11:13:25","AP01SDTM":"2020-03-18 17:13:25","AP01EDTM":"2022-03-19 05:13:25","AP02SDTM":"2022-03-19 05:13:25","AP02EDTM":"2023-03-19 11:13:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-19","EOSDY":1096,"LSTALVDT":"2023-04-17","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1386,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86358,"AVALU":"g/L","BASE2":2.91847,"BASE":2.8044,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.05489,"PCHG2":-1.88081,"CHG":0.05918,"PCHG":2.11021,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-06 17:13:25","ADY":567,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-343","SUBJID":"id-343","SITEID":"USA-12","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.75539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-15","TRTSDTM":"2020-03-18 17:13:25","TRTEDTM":"2023-03-19 11:13:25","TRT01SDTM":"2020-03-18 17:13:25","TRT01EDTM":"2022-03-19 05:13:25","TRT02SDTM":"2022-03-19 05:13:25","TRT02EDTM":"2023-03-19 11:13:25","AP01SDTM":"2020-03-18 17:13:25","AP01EDTM":"2022-03-19 05:13:25","AP02SDTM":"2022-03-19 05:13:25","AP02EDTM":"2023-03-19 11:13:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-19","EOSDY":1096,"LSTALVDT":"2023-04-17","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4862,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88579,"AVALU":"g/L","BASE2":2.91847,"BASE":2.8044,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03268,"PCHG2":-1.11979,"CHG":0.08139,"PCHG":2.90218,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-09-26 17:13:25","ADY":922,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-343","SUBJID":"id-343","SITEID":"USA-12","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.75539,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-03-15","TRTSDTM":"2020-03-18 17:13:25","TRTEDTM":"2023-03-19 11:13:25","TRT01SDTM":"2020-03-18 17:13:25","TRT01EDTM":"2022-03-19 05:13:25","TRT02SDTM":"2022-03-19 05:13:25","TRT02EDTM":"2023-03-19 11:13:25","AP01SDTM":"2020-03-18 17:13:25","AP01EDTM":"2022-03-19 05:13:25","AP02SDTM":"2022-03-19 05:13:25","AP02EDTM":"2023-03-19 11:13:25","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-03-19","EOSDY":1096,"LSTALVDT":"2023-04-17","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1341,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97122,"AVALU":"g/L","BASE2":2.91847,"BASE":2.8044,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.05275,"PCHG2":1.80742,"CHG":0.16682,"PCHG":5.94845,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-02-28 17:13:25","ADY":1077,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-44","SUBJID":"id-44","SITEID":"USA-12","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.53653,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 00:35:06","TRTEDTM":"2022-04-27 18:35:06","TRT01SDTM":"2019-04-28 00:35:06","TRT01EDTM":"2021-04-27 12:35:06","TRT02SDTM":"2021-04-27 12:35:06","TRT02EDTM":"2022-04-27 18:35:06","AP01SDTM":"2019-04-28 00:35:06","AP01EDTM":"2021-04-27 12:35:06","AP02SDTM":"2021-04-27 12:35:06","AP02EDTM":"2022-04-27 18:35:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1340,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":31.5868,"AVALU":"U/L","BASE2":31.5868,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-05-09 00:35:06","ADY":11,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-44","SUBJID":"id-44","SITEID":"USA-12","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.53653,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 00:35:06","TRTEDTM":"2022-04-27 18:35:06","TRT01SDTM":"2019-04-28 00:35:06","TRT01EDTM":"2021-04-27 12:35:06","TRT02SDTM":"2021-04-27 12:35:06","TRT02EDTM":"2022-04-27 18:35:06","AP01SDTM":"2019-04-28 00:35:06","AP01EDTM":"2021-04-27 12:35:06","AP02SDTM":"2021-04-27 12:35:06","AP02EDTM":"2022-04-27 18:35:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2789,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.03728,"AVALU":"U/L","BASE2":31.5868,"BASE":15.03728,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-16.54951,"PCHG2":-52.39377,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-05-19 00:35:06","ADY":21,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-44","SUBJID":"id-44","SITEID":"USA-12","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.53653,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 00:35:06","TRTEDTM":"2022-04-27 18:35:06","TRT01SDTM":"2019-04-28 00:35:06","TRT01EDTM":"2021-04-27 12:35:06","TRT02SDTM":"2021-04-27 12:35:06","TRT02EDTM":"2022-04-27 18:35:06","AP01SDTM":"2019-04-28 00:35:06","AP01EDTM":"2021-04-27 12:35:06","AP02SDTM":"2021-04-27 12:35:06","AP02EDTM":"2022-04-27 18:35:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":649,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.38441,"AVALU":"U/L","BASE2":31.5868,"BASE":15.03728,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-19.20238,"PCHG2":-60.79244,"CHG":-2.65287,"PCHG":-17.64194,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-07 00:35:06","ADY":375,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-44","SUBJID":"id-44","SITEID":"USA-12","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.53653,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 00:35:06","TRTEDTM":"2022-04-27 18:35:06","TRT01SDTM":"2019-04-28 00:35:06","TRT01EDTM":"2021-04-27 12:35:06","TRT02SDTM":"2021-04-27 12:35:06","TRT02EDTM":"2022-04-27 18:35:06","AP01SDTM":"2019-04-28 00:35:06","AP01EDTM":"2021-04-27 12:35:06","AP02SDTM":"2021-04-27 12:35:06","AP02EDTM":"2022-04-27 18:35:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2219,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.3476,"AVALU":"U/L","BASE2":31.5868,"BASE":15.03728,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-31.2392,"PCHG2":-98.89955,"CHG":-14.68969,"PCHG":-97.68844,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-04-01 00:35:06","ADY":704,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-44","SUBJID":"id-44","SITEID":"USA-12","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.53653,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 00:35:06","TRTEDTM":"2022-04-27 18:35:06","TRT01SDTM":"2019-04-28 00:35:06","TRT01EDTM":"2021-04-27 12:35:06","TRT02SDTM":"2021-04-27 12:35:06","TRT02EDTM":"2022-04-27 18:35:06","AP01SDTM":"2019-04-28 00:35:06","AP01EDTM":"2021-04-27 12:35:06","AP02SDTM":"2021-04-27 12:35:06","AP02EDTM":"2022-04-27 18:35:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1158,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.3398,"AVALU":"U/L","BASE2":31.5868,"BASE":15.03728,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.753,"PCHG2":2.38392,"CHG":17.30252,"PCHG":115.06414,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-08 00:35:06","ADY":925,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-44","SUBJID":"id-44","SITEID":"USA-12","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.53653,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 00:35:06","TRTEDTM":"2022-04-27 18:35:06","TRT01SDTM":"2019-04-28 00:35:06","TRT01EDTM":"2021-04-27 12:35:06","TRT02SDTM":"2021-04-27 12:35:06","TRT02EDTM":"2022-04-27 18:35:06","AP01SDTM":"2019-04-28 00:35:06","AP01EDTM":"2021-04-27 12:35:06","AP02SDTM":"2021-04-27 12:35:06","AP02EDTM":"2022-04-27 18:35:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1077,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":9.44658,"AVALU":"U/L","BASE2":31.5868,"BASE":15.03728,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-22.14021,"PCHG2":-70.09325,"CHG":-5.5907,"PCHG":-37.17891,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-29 00:35:06","ADY":1007,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-44","SUBJID":"id-44","SITEID":"USA-12","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.53653,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 00:35:06","TRTEDTM":"2022-04-27 18:35:06","TRT01SDTM":"2019-04-28 00:35:06","TRT01EDTM":"2021-04-27 12:35:06","TRT02SDTM":"2021-04-27 12:35:06","TRT02EDTM":"2022-04-27 18:35:06","AP01SDTM":"2019-04-28 00:35:06","AP01EDTM":"2021-04-27 12:35:06","AP02SDTM":"2021-04-27 12:35:06","AP02EDTM":"2022-04-27 18:35:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4867,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.30699,"AVALU":"U/L","BASE2":31.5868,"BASE":15.03728,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-24.2798,"PCHG2":-76.86693,"CHG":-7.73029,"PCHG":-51.40747,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-06 00:35:06","ADY":1015,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-44","SUBJID":"id-44","SITEID":"USA-12","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.53653,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 00:35:06","TRTEDTM":"2022-04-27 18:35:06","TRT01SDTM":"2019-04-28 00:35:06","TRT01EDTM":"2021-04-27 12:35:06","TRT02SDTM":"2021-04-27 12:35:06","TRT02EDTM":"2022-04-27 18:35:06","AP01SDTM":"2019-04-28 00:35:06","AP01EDTM":"2021-04-27 12:35:06","AP02SDTM":"2021-04-27 12:35:06","AP02EDTM":"2022-04-27 18:35:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7122,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.3138,"AVALU":"mg/L","BASE2":10.3138,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2019-05-09 00:35:06","ADY":11,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-44","SUBJID":"id-44","SITEID":"USA-12","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.53653,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 00:35:06","TRTEDTM":"2022-04-27 18:35:06","TRT01SDTM":"2019-04-28 00:35:06","TRT01EDTM":"2021-04-27 12:35:06","TRT02SDTM":"2021-04-27 12:35:06","TRT02EDTM":"2022-04-27 18:35:06","AP01SDTM":"2019-04-28 00:35:06","AP01EDTM":"2021-04-27 12:35:06","AP02SDTM":"2021-04-27 12:35:06","AP02EDTM":"2022-04-27 18:35:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8257,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.17777,"AVALU":"mg/L","BASE2":10.3138,"BASE":9.17777,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.13602,"PCHG2":-11.0146,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-05-19 00:35:06","ADY":21,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-44","SUBJID":"id-44","SITEID":"USA-12","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.53653,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 00:35:06","TRTEDTM":"2022-04-27 18:35:06","TRT01SDTM":"2019-04-28 00:35:06","TRT01EDTM":"2021-04-27 12:35:06","TRT02SDTM":"2021-04-27 12:35:06","TRT02EDTM":"2022-04-27 18:35:06","AP01SDTM":"2019-04-28 00:35:06","AP01EDTM":"2021-04-27 12:35:06","AP02SDTM":"2021-04-27 12:35:06","AP02EDTM":"2022-04-27 18:35:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4043,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.28521,"AVALU":"mg/L","BASE2":10.3138,"BASE":9.17777,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02858,"PCHG2":-0.27714,"CHG":1.10744,"PCHG":12.06654,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-05-07 00:35:06","ADY":375,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-44","SUBJID":"id-44","SITEID":"USA-12","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.53653,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 00:35:06","TRTEDTM":"2022-04-27 18:35:06","TRT01SDTM":"2019-04-28 00:35:06","TRT01EDTM":"2021-04-27 12:35:06","TRT02SDTM":"2021-04-27 12:35:06","TRT02EDTM":"2022-04-27 18:35:06","AP01SDTM":"2019-04-28 00:35:06","AP01EDTM":"2021-04-27 12:35:06","AP02SDTM":"2021-04-27 12:35:06","AP02EDTM":"2022-04-27 18:35:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6572,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.67642,"AVALU":"mg/L","BASE2":10.3138,"BASE":9.17777,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.63738,"PCHG2":-35.26714,"CHG":-2.50136,"PCHG":-27.25451,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-04-01 00:35:06","ADY":704,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-44","SUBJID":"id-44","SITEID":"USA-12","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.53653,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 00:35:06","TRTEDTM":"2022-04-27 18:35:06","TRT01SDTM":"2019-04-28 00:35:06","TRT01EDTM":"2021-04-27 12:35:06","TRT02SDTM":"2021-04-27 12:35:06","TRT02EDTM":"2022-04-27 18:35:06","AP01SDTM":"2019-04-28 00:35:06","AP01EDTM":"2021-04-27 12:35:06","AP02SDTM":"2021-04-27 12:35:06","AP02EDTM":"2022-04-27 18:35:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7668,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.83082,"AVALU":"mg/L","BASE2":10.3138,"BASE":9.17777,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.51702,"PCHG2":5.01286,"CHG":1.65304,"PCHG":18.01134,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-11-08 00:35:06","ADY":925,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-44","SUBJID":"id-44","SITEID":"USA-12","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.53653,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 00:35:06","TRTEDTM":"2022-04-27 18:35:06","TRT01SDTM":"2019-04-28 00:35:06","TRT01EDTM":"2021-04-27 12:35:06","TRT02SDTM":"2021-04-27 12:35:06","TRT02EDTM":"2022-04-27 18:35:06","AP01SDTM":"2019-04-28 00:35:06","AP01EDTM":"2021-04-27 12:35:06","AP02SDTM":"2021-04-27 12:35:06","AP02EDTM":"2022-04-27 18:35:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8335,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.7181,"AVALU":"mg/L","BASE2":10.3138,"BASE":9.17777,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.5957,"PCHG2":-15.47154,"CHG":-0.45968,"PCHG":-5.00862,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-29 00:35:06","ADY":1007,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-44","SUBJID":"id-44","SITEID":"USA-12","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.53653,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 00:35:06","TRTEDTM":"2022-04-27 18:35:06","TRT01SDTM":"2019-04-28 00:35:06","TRT01EDTM":"2021-04-27 12:35:06","TRT02SDTM":"2021-04-27 12:35:06","TRT02EDTM":"2022-04-27 18:35:06","AP01SDTM":"2019-04-28 00:35:06","AP01EDTM":"2021-04-27 12:35:06","AP02SDTM":"2021-04-27 12:35:06","AP02EDTM":"2022-04-27 18:35:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":740,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.00484,"AVALU":"mg/L","BASE2":10.3138,"BASE":9.17777,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.30896,"PCHG2":-12.69132,"CHG":-0.17293,"PCHG":-1.88426,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-06 00:35:06","ADY":1015,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-44","SUBJID":"id-44","SITEID":"USA-12","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.53653,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 00:35:06","TRTEDTM":"2022-04-27 18:35:06","TRT01SDTM":"2019-04-28 00:35:06","TRT01EDTM":"2021-04-27 12:35:06","TRT02SDTM":"2021-04-27 12:35:06","TRT02EDTM":"2022-04-27 18:35:06","AP01SDTM":"2019-04-28 00:35:06","AP01EDTM":"2021-04-27 12:35:06","AP02SDTM":"2021-04-27 12:35:06","AP02EDTM":"2022-04-27 18:35:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2852,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85843,"AVALU":"g/L","BASE2":2.85843,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-05-09 00:35:06","ADY":11,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-44","SUBJID":"id-44","SITEID":"USA-12","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.53653,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 00:35:06","TRTEDTM":"2022-04-27 18:35:06","TRT01SDTM":"2019-04-28 00:35:06","TRT01EDTM":"2021-04-27 12:35:06","TRT02SDTM":"2021-04-27 12:35:06","TRT02EDTM":"2022-04-27 18:35:06","AP01SDTM":"2019-04-28 00:35:06","AP01EDTM":"2021-04-27 12:35:06","AP02SDTM":"2021-04-27 12:35:06","AP02EDTM":"2022-04-27 18:35:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1795,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83804,"AVALU":"g/L","BASE2":2.85843,"BASE":2.83804,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.02039,"PCHG2":-0.71334,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-05-19 00:35:06","ADY":21,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-44","SUBJID":"id-44","SITEID":"USA-12","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.53653,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 00:35:06","TRTEDTM":"2022-04-27 18:35:06","TRT01SDTM":"2019-04-28 00:35:06","TRT01EDTM":"2021-04-27 12:35:06","TRT02SDTM":"2021-04-27 12:35:06","TRT02EDTM":"2022-04-27 18:35:06","AP01SDTM":"2019-04-28 00:35:06","AP01EDTM":"2021-04-27 12:35:06","AP02SDTM":"2021-04-27 12:35:06","AP02EDTM":"2022-04-27 18:35:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2998,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87592,"AVALU":"g/L","BASE2":2.85843,"BASE":2.83804,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01749,"PCHG2":0.61196,"CHG":0.03788,"PCHG":1.33482,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-07 00:35:06","ADY":375,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-44","SUBJID":"id-44","SITEID":"USA-12","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.53653,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 00:35:06","TRTEDTM":"2022-04-27 18:35:06","TRT01SDTM":"2019-04-28 00:35:06","TRT01EDTM":"2021-04-27 12:35:06","TRT02SDTM":"2021-04-27 12:35:06","TRT02EDTM":"2022-04-27 18:35:06","AP01SDTM":"2019-04-28 00:35:06","AP01EDTM":"2021-04-27 12:35:06","AP02SDTM":"2021-04-27 12:35:06","AP02EDTM":"2022-04-27 18:35:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":927,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9301,"AVALU":"g/L","BASE2":2.85843,"BASE":2.83804,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07167,"PCHG2":2.50747,"CHG":0.09206,"PCHG":3.24396,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-01 00:35:06","ADY":704,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-44","SUBJID":"id-44","SITEID":"USA-12","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.53653,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 00:35:06","TRTEDTM":"2022-04-27 18:35:06","TRT01SDTM":"2019-04-28 00:35:06","TRT01EDTM":"2021-04-27 12:35:06","TRT02SDTM":"2021-04-27 12:35:06","TRT02EDTM":"2022-04-27 18:35:06","AP01SDTM":"2019-04-28 00:35:06","AP01EDTM":"2021-04-27 12:35:06","AP02SDTM":"2021-04-27 12:35:06","AP02EDTM":"2022-04-27 18:35:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":515,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93178,"AVALU":"g/L","BASE2":2.85843,"BASE":2.83804,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.07335,"PCHG2":2.56627,"CHG":0.09375,"PCHG":3.30317,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-08 00:35:06","ADY":925,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-44","SUBJID":"id-44","SITEID":"USA-12","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.53653,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 00:35:06","TRTEDTM":"2022-04-27 18:35:06","TRT01SDTM":"2019-04-28 00:35:06","TRT01EDTM":"2021-04-27 12:35:06","TRT02SDTM":"2021-04-27 12:35:06","TRT02EDTM":"2022-04-27 18:35:06","AP01SDTM":"2019-04-28 00:35:06","AP01EDTM":"2021-04-27 12:35:06","AP02SDTM":"2021-04-27 12:35:06","AP02EDTM":"2022-04-27 18:35:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2939,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89966,"AVALU":"g/L","BASE2":2.85843,"BASE":2.83804,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04123,"PCHG2":1.44243,"CHG":0.06162,"PCHG":2.17126,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-29 00:35:06","ADY":1007,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-12-id-44","SUBJID":"id-44","SITEID":"USA-12","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-12","INVNAM":"Dr. USA-12 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":8.53653,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-04-28","TRTSDTM":"2019-04-28 00:35:06","TRTEDTM":"2022-04-27 18:35:06","TRT01SDTM":"2019-04-28 00:35:06","TRT01EDTM":"2021-04-27 12:35:06","TRT02SDTM":"2021-04-27 12:35:06","TRT02EDTM":"2022-04-27 18:35:06","AP01SDTM":"2019-04-28 00:35:06","AP01EDTM":"2021-04-27 12:35:06","AP02SDTM":"2021-04-27 12:35:06","AP02EDTM":"2022-04-27 18:35:06","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-04-27","EOSDY":1096,"LSTALVDT":"2022-05-20","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6463,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93682,"AVALU":"g/L","BASE2":2.85843,"BASE":2.83804,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.0784,"PCHG2":2.74269,"CHG":0.09879,"PCHG":3.48086,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-06 00:35:06","ADY":1015,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-14-id-196","SUBJID":"id-196","SITEID":"USA-14","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-14","INVNAM":"Dr. USA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.92637,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-22","TRTSDTM":"2020-01-25 11:41:32","TRT01SDTM":"2020-01-25 11:41:32","AP01SDTM":"2020-01-25 11:41:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2827,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.22896,"AVALU":"U/L","BASE2":16.22896,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-04-01 11:41:32","ADY":67,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-14-id-196","SUBJID":"id-196","SITEID":"USA-14","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-14","INVNAM":"Dr. USA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.92637,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-22","TRTSDTM":"2020-01-25 11:41:32","TRT01SDTM":"2020-01-25 11:41:32","AP01SDTM":"2020-01-25 11:41:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":93,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.51197,"AVALU":"U/L","BASE2":16.22896,"BASE":5.51197,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-10.71699,"PCHG2":-66.03624,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2020-06-03 11:41:32","ADY":130,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-14-id-196","SUBJID":"id-196","SITEID":"USA-14","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-14","INVNAM":"Dr. USA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.92637,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-22","TRTSDTM":"2020-01-25 11:41:32","TRT01SDTM":"2020-01-25 11:41:32","AP01SDTM":"2020-01-25 11:41:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1289,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.13342,"AVALU":"U/L","BASE2":16.22896,"BASE":5.51197,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.90446,"PCHG2":11.73493,"CHG":12.62145,"PCHG":228.98277,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2020-07-09 11:41:32","ADY":166,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-14-id-196","SUBJID":"id-196","SITEID":"USA-14","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-14","INVNAM":"Dr. USA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.92637,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-22","TRTSDTM":"2020-01-25 11:41:32","TRT01SDTM":"2020-01-25 11:41:32","AP01SDTM":"2020-01-25 11:41:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8122,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.9737,"AVALU":"U/L","BASE2":16.22896,"BASE":5.51197,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-10.25526,"PCHG2":-63.19113,"CHG":0.46173,"PCHG":8.37689,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2020-09-03 11:41:32","ADY":222,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-14-id-196","SUBJID":"id-196","SITEID":"USA-14","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-14","INVNAM":"Dr. USA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.92637,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-22","TRTSDTM":"2020-01-25 11:41:32","TRT01SDTM":"2020-01-25 11:41:32","AP01SDTM":"2020-01-25 11:41:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1336,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.22625,"AVALU":"U/L","BASE2":16.22896,"BASE":5.51197,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-5.00271,"PCHG2":-30.82584,"CHG":5.71428,"PCHG":103.67047,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-04-28 11:41:32","ADY":459,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-14-id-196","SUBJID":"id-196","SITEID":"USA-14","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-14","INVNAM":"Dr. USA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.92637,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-22","TRTSDTM":"2020-01-25 11:41:32","TRT01SDTM":"2020-01-25 11:41:32","AP01SDTM":"2020-01-25 11:41:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1207,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.44743,"AVALU":"U/L","BASE2":16.22896,"BASE":5.51197,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.21847,"PCHG2":7.50801,"CHG":11.93547,"PCHG":216.53738,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-07-26 11:41:32","ADY":548,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-14-id-196","SUBJID":"id-196","SITEID":"USA-14","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-14","INVNAM":"Dr. USA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.92637,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-22","TRTSDTM":"2020-01-25 11:41:32","TRT01SDTM":"2020-01-25 11:41:32","AP01SDTM":"2020-01-25 11:41:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":309,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.60358,"AVALU":"U/L","BASE2":16.22896,"BASE":5.51197,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.37462,"PCHG2":45.44114,"CHG":18.09162,"PCHG":328.22443,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2021-08-22 11:41:32","ADY":575,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-14-id-196","SUBJID":"id-196","SITEID":"USA-14","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-14","INVNAM":"Dr. USA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.92637,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-22","TRTSDTM":"2020-01-25 11:41:32","TRT01SDTM":"2020-01-25 11:41:32","AP01SDTM":"2020-01-25 11:41:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1102,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.12125,"AVALU":"mg/L","BASE2":8.12125,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-01 11:41:32","ADY":67,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-14-id-196","SUBJID":"id-196","SITEID":"USA-14","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-14","INVNAM":"Dr. USA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.92637,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-22","TRTSDTM":"2020-01-25 11:41:32","TRT01SDTM":"2020-01-25 11:41:32","AP01SDTM":"2020-01-25 11:41:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5940,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.76255,"AVALU":"mg/L","BASE2":8.12125,"BASE":8.76255,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.6413,"PCHG2":7.89651,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-03 11:41:32","ADY":130,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-14-id-196","SUBJID":"id-196","SITEID":"USA-14","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-14","INVNAM":"Dr. USA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.92637,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-22","TRTSDTM":"2020-01-25 11:41:32","TRT01SDTM":"2020-01-25 11:41:32","AP01SDTM":"2020-01-25 11:41:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4463,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.68969,"AVALU":"mg/L","BASE2":8.12125,"BASE":8.76255,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.56844,"PCHG2":6.99943,"CHG":-0.07285,"PCHG":-0.83143,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-09 11:41:32","ADY":166,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-14-id-196","SUBJID":"id-196","SITEID":"USA-14","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-14","INVNAM":"Dr. USA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.92637,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-22","TRTSDTM":"2020-01-25 11:41:32","TRT01SDTM":"2020-01-25 11:41:32","AP01SDTM":"2020-01-25 11:41:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5392,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.5217,"AVALU":"mg/L","BASE2":8.12125,"BASE":8.76255,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.40045,"PCHG2":17.24421,"CHG":0.75915,"PCHG":8.66358,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-03 11:41:32","ADY":222,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-14-id-196","SUBJID":"id-196","SITEID":"USA-14","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-14","INVNAM":"Dr. USA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.92637,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-22","TRTSDTM":"2020-01-25 11:41:32","TRT01SDTM":"2020-01-25 11:41:32","AP01SDTM":"2020-01-25 11:41:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":887,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.67321,"AVALU":"mg/L","BASE2":8.12125,"BASE":8.76255,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.44804,"PCHG2":-5.51689,"CHG":-1.08934,"PCHG":-12.43173,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-04-28 11:41:32","ADY":459,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-14-id-196","SUBJID":"id-196","SITEID":"USA-14","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-14","INVNAM":"Dr. USA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.92637,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-22","TRTSDTM":"2020-01-25 11:41:32","TRT01SDTM":"2020-01-25 11:41:32","AP01SDTM":"2020-01-25 11:41:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7102,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.92465,"AVALU":"mg/L","BASE2":8.12125,"BASE":8.76255,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.1966,"PCHG2":-14.73422,"CHG":-1.8379,"PCHG":-20.97448,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-07-26 11:41:32","ADY":548,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-14-id-196","SUBJID":"id-196","SITEID":"USA-14","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-14","INVNAM":"Dr. USA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.92637,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-22","TRTSDTM":"2020-01-25 11:41:32","TRT01SDTM":"2020-01-25 11:41:32","AP01SDTM":"2020-01-25 11:41:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":30,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.34757,"AVALU":"mg/L","BASE2":8.12125,"BASE":8.76255,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.22632,"PCHG2":15.10012,"CHG":0.58502,"PCHG":6.67641,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-22 11:41:32","ADY":575,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-14-id-196","SUBJID":"id-196","SITEID":"USA-14","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-14","INVNAM":"Dr. USA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.92637,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-22","TRTSDTM":"2020-01-25 11:41:32","TRT01SDTM":"2020-01-25 11:41:32","AP01SDTM":"2020-01-25 11:41:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":702,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9565,"AVALU":"g/L","BASE2":2.9565,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-01 11:41:32","ADY":67,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-14-id-196","SUBJID":"id-196","SITEID":"USA-14","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-14","INVNAM":"Dr. USA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.92637,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-22","TRTSDTM":"2020-01-25 11:41:32","TRT01SDTM":"2020-01-25 11:41:32","AP01SDTM":"2020-01-25 11:41:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5400,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94021,"AVALU":"g/L","BASE2":2.9565,"BASE":2.94021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.01628,"PCHG2":-0.55079,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-03 11:41:32","ADY":130,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-14-id-196","SUBJID":"id-196","SITEID":"USA-14","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-14","INVNAM":"Dr. USA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.92637,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-22","TRTSDTM":"2020-01-25 11:41:32","TRT01SDTM":"2020-01-25 11:41:32","AP01SDTM":"2020-01-25 11:41:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":759,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92373,"AVALU":"g/L","BASE2":2.9565,"BASE":2.94021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03276,"PCHG2":-1.10823,"CHG":-0.01648,"PCHG":-0.56053,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-09 11:41:32","ADY":166,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-14-id-196","SUBJID":"id-196","SITEID":"USA-14","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-14","INVNAM":"Dr. USA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.92637,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-22","TRTSDTM":"2020-01-25 11:41:32","TRT01SDTM":"2020-01-25 11:41:32","AP01SDTM":"2020-01-25 11:41:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8062,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98303,"AVALU":"g/L","BASE2":2.9565,"BASE":2.94021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02653,"PCHG2":0.89751,"CHG":0.04282,"PCHG":1.45632,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-03 11:41:32","ADY":222,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-14-id-196","SUBJID":"id-196","SITEID":"USA-14","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-14","INVNAM":"Dr. USA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.92637,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-22","TRTSDTM":"2020-01-25 11:41:32","TRT01SDTM":"2020-01-25 11:41:32","AP01SDTM":"2020-01-25 11:41:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5215,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76645,"AVALU":"g/L","BASE2":2.9565,"BASE":2.94021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19004,"PCHG2":-6.42802,"CHG":-0.17376,"PCHG":-5.90978,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-28 11:41:32","ADY":459,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-14-id-196","SUBJID":"id-196","SITEID":"USA-14","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-14","INVNAM":"Dr. USA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.92637,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-22","TRTSDTM":"2020-01-25 11:41:32","TRT01SDTM":"2020-01-25 11:41:32","AP01SDTM":"2020-01-25 11:41:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1751,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.905,"AVALU":"g/L","BASE2":2.9565,"BASE":2.94021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0515,"PCHG2":-1.74177,"CHG":-0.03521,"PCHG":-1.19757,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-26 11:41:32","ADY":548,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-14-id-196","SUBJID":"id-196","SITEID":"USA-14","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-14","INVNAM":"Dr. USA-14 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":3.92637,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-01-22","TRTSDTM":"2020-01-25 11:41:32","TRT01SDTM":"2020-01-25 11:41:32","AP01SDTM":"2020-01-25 11:41:32","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4714,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94457,"AVALU":"g/L","BASE2":2.9565,"BASE":2.94021,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01193,"PCHG2":-0.40345,"CHG":0.00436,"PCHG":0.14815,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-22 11:41:32","ADY":575,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-127","SUBJID":"id-127","SITEID":"USA-15","AGE":57,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.37225,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 00:32:46","TRTEDTM":"2022-05-11 18:32:46","TRT01SDTM":"2019-05-12 00:32:46","TRT01EDTM":"2021-05-11 12:32:46","TRT02SDTM":"2021-05-11 12:32:46","TRT02EDTM":"2022-05-11 18:32:46","AP01SDTM":"2019-05-12 00:32:46","AP01EDTM":"2021-05-11 12:32:46","AP02SDTM":"2021-05-11 12:32:46","AP02EDTM":"2022-05-11 18:32:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-11","EOSDY":1096,"LSTALVDT":"2022-05-25","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6093,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.63176,"AVALU":"U/L","BASE2":25.63176,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"","ATOXGR":"0","BTOXGR":"-2","ADTM":"2020-06-09 00:32:46","ADY":394,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-127","SUBJID":"id-127","SITEID":"USA-15","AGE":57,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.37225,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 00:32:46","TRTEDTM":"2022-05-11 18:32:46","TRT01SDTM":"2019-05-12 00:32:46","TRT01EDTM":"2021-05-11 12:32:46","TRT02SDTM":"2021-05-11 12:32:46","TRT02EDTM":"2022-05-11 18:32:46","AP01SDTM":"2019-05-12 00:32:46","AP01EDTM":"2021-05-11 12:32:46","AP02SDTM":"2021-05-11 12:32:46","AP02EDTM":"2022-05-11 18:32:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-11","EOSDY":1096,"LSTALVDT":"2022-05-25","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2142,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.4789,"AVALU":"U/L","BASE2":25.63176,"BASE":1.4789,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-24.15286,"PCHG2":-94.23022,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-2","BTOXGR":"-2","ADTM":"2020-12-24 00:32:46","ADY":592,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-127","SUBJID":"id-127","SITEID":"USA-15","AGE":57,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.37225,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 00:32:46","TRTEDTM":"2022-05-11 18:32:46","TRT01SDTM":"2019-05-12 00:32:46","TRT01EDTM":"2021-05-11 12:32:46","TRT02SDTM":"2021-05-11 12:32:46","TRT02EDTM":"2022-05-11 18:32:46","AP01SDTM":"2019-05-12 00:32:46","AP01EDTM":"2021-05-11 12:32:46","AP02SDTM":"2021-05-11 12:32:46","AP02EDTM":"2022-05-11 18:32:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-11","EOSDY":1096,"LSTALVDT":"2022-05-25","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3352,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.8075,"AVALU":"U/L","BASE2":25.63176,"BASE":1.4789,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.17575,"PCHG2":31.89694,"CHG":32.32861,"PCHG":2185.99403,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-01-30 00:32:46","ADY":629,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-127","SUBJID":"id-127","SITEID":"USA-15","AGE":57,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.37225,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 00:32:46","TRTEDTM":"2022-05-11 18:32:46","TRT01SDTM":"2019-05-12 00:32:46","TRT01EDTM":"2021-05-11 12:32:46","TRT02SDTM":"2021-05-11 12:32:46","TRT02EDTM":"2022-05-11 18:32:46","AP01SDTM":"2019-05-12 00:32:46","AP01EDTM":"2021-05-11 12:32:46","AP02SDTM":"2021-05-11 12:32:46","AP02EDTM":"2022-05-11 18:32:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-11","EOSDY":1096,"LSTALVDT":"2022-05-25","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3263,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.42398,"AVALU":"U/L","BASE2":25.63176,"BASE":1.4789,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.20777,"PCHG2":-24.21907,"CHG":17.94509,"PCHG":1213.40993,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-04-27 00:32:46","ADY":716,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-127","SUBJID":"id-127","SITEID":"USA-15","AGE":57,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.37225,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 00:32:46","TRTEDTM":"2022-05-11 18:32:46","TRT01SDTM":"2019-05-12 00:32:46","TRT01EDTM":"2021-05-11 12:32:46","TRT02SDTM":"2021-05-11 12:32:46","TRT02EDTM":"2022-05-11 18:32:46","AP01SDTM":"2019-05-12 00:32:46","AP01EDTM":"2021-05-11 12:32:46","AP02SDTM":"2021-05-11 12:32:46","AP02EDTM":"2022-05-11 18:32:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-11","EOSDY":1096,"LSTALVDT":"2022-05-25","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3407,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.98588,"AVALU":"U/L","BASE2":25.63176,"BASE":1.4789,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.64588,"PCHG2":-14.22406,"CHG":20.50698,"PCHG":1386.64013,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2021-10-10 00:32:46","ADY":882,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-127","SUBJID":"id-127","SITEID":"USA-15","AGE":57,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.37225,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 00:32:46","TRTEDTM":"2022-05-11 18:32:46","TRT01SDTM":"2019-05-12 00:32:46","TRT01EDTM":"2021-05-11 12:32:46","TRT02SDTM":"2021-05-11 12:32:46","TRT02EDTM":"2022-05-11 18:32:46","AP01SDTM":"2019-05-12 00:32:46","AP01EDTM":"2021-05-11 12:32:46","AP02SDTM":"2021-05-11 12:32:46","AP02EDTM":"2022-05-11 18:32:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-11","EOSDY":1096,"LSTALVDT":"2022-05-25","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4037,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.50149,"AVALU":"U/L","BASE2":25.63176,"BASE":1.4789,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-9.13027,"PCHG2":-35.62094,"CHG":15.02259,"PCHG":1015.79658,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-01-01 00:32:46","ADY":965,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-127","SUBJID":"id-127","SITEID":"USA-15","AGE":57,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.37225,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 00:32:46","TRTEDTM":"2022-05-11 18:32:46","TRT01SDTM":"2019-05-12 00:32:46","TRT01EDTM":"2021-05-11 12:32:46","TRT02SDTM":"2021-05-11 12:32:46","TRT02EDTM":"2022-05-11 18:32:46","AP01SDTM":"2019-05-12 00:32:46","AP01EDTM":"2021-05-11 12:32:46","AP02SDTM":"2021-05-11 12:32:46","AP02EDTM":"2022-05-11 18:32:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-11","EOSDY":1096,"LSTALVDT":"2022-05-25","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1905,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.55969,"AVALU":"U/L","BASE2":25.63176,"BASE":1.4789,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.07207,"PCHG2":-47.09811,"CHG":12.08079,"PCHG":816.87808,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-2","ADTM":"2022-02-14 00:32:46","ADY":1009,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"2","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-127","SUBJID":"id-127","SITEID":"USA-15","AGE":57,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.37225,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 00:32:46","TRTEDTM":"2022-05-11 18:32:46","TRT01SDTM":"2019-05-12 00:32:46","TRT01EDTM":"2021-05-11 12:32:46","TRT02SDTM":"2021-05-11 12:32:46","TRT02EDTM":"2022-05-11 18:32:46","AP01SDTM":"2019-05-12 00:32:46","AP01EDTM":"2021-05-11 12:32:46","AP02SDTM":"2021-05-11 12:32:46","AP02EDTM":"2022-05-11 18:32:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-11","EOSDY":1096,"LSTALVDT":"2022-05-25","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7410,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.6952,"AVALU":"mg/L","BASE2":7.6952,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"-3","BTOXGR":"0","ADTM":"2020-06-09 00:32:46","ADY":394,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-127","SUBJID":"id-127","SITEID":"USA-15","AGE":57,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.37225,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 00:32:46","TRTEDTM":"2022-05-11 18:32:46","TRT01SDTM":"2019-05-12 00:32:46","TRT01EDTM":"2021-05-11 12:32:46","TRT02SDTM":"2021-05-11 12:32:46","TRT02EDTM":"2022-05-11 18:32:46","AP01SDTM":"2019-05-12 00:32:46","AP01EDTM":"2021-05-11 12:32:46","AP02SDTM":"2021-05-11 12:32:46","AP02EDTM":"2022-05-11 18:32:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-11","EOSDY":1096,"LSTALVDT":"2022-05-25","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2595,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.86452,"AVALU":"mg/L","BASE2":7.6952,"BASE":9.86452,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":2.16931,"PCHG2":28.19044,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-24 00:32:46","ADY":592,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-127","SUBJID":"id-127","SITEID":"USA-15","AGE":57,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.37225,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 00:32:46","TRTEDTM":"2022-05-11 18:32:46","TRT01SDTM":"2019-05-12 00:32:46","TRT01EDTM":"2021-05-11 12:32:46","TRT02SDTM":"2021-05-11 12:32:46","TRT02EDTM":"2022-05-11 18:32:46","AP01SDTM":"2019-05-12 00:32:46","AP01EDTM":"2021-05-11 12:32:46","AP02SDTM":"2021-05-11 12:32:46","AP02EDTM":"2022-05-11 18:32:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-11","EOSDY":1096,"LSTALVDT":"2022-05-25","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4399,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":6.84071,"AVALU":"mg/L","BASE2":7.6952,"BASE":9.86452,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.85449,"PCHG2":-11.10425,"CHG":-3.02381,"PCHG":-30.65337,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-01-30 00:32:46","ADY":629,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-127","SUBJID":"id-127","SITEID":"USA-15","AGE":57,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.37225,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 00:32:46","TRTEDTM":"2022-05-11 18:32:46","TRT01SDTM":"2019-05-12 00:32:46","TRT01EDTM":"2021-05-11 12:32:46","TRT02SDTM":"2021-05-11 12:32:46","TRT02EDTM":"2022-05-11 18:32:46","AP01SDTM":"2019-05-12 00:32:46","AP01EDTM":"2021-05-11 12:32:46","AP02SDTM":"2021-05-11 12:32:46","AP02EDTM":"2022-05-11 18:32:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-11","EOSDY":1096,"LSTALVDT":"2022-05-25","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7848,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.84389,"AVALU":"mg/L","BASE2":7.6952,"BASE":9.86452,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.14869,"PCHG2":40.9175,"CHG":0.97937,"PCHG":9.92824,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-04-27 00:32:46","ADY":716,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-127","SUBJID":"id-127","SITEID":"USA-15","AGE":57,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.37225,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 00:32:46","TRTEDTM":"2022-05-11 18:32:46","TRT01SDTM":"2019-05-12 00:32:46","TRT01EDTM":"2021-05-11 12:32:46","TRT02SDTM":"2021-05-11 12:32:46","TRT02EDTM":"2022-05-11 18:32:46","AP01SDTM":"2019-05-12 00:32:46","AP01EDTM":"2021-05-11 12:32:46","AP02SDTM":"2021-05-11 12:32:46","AP02EDTM":"2022-05-11 18:32:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-11","EOSDY":1096,"LSTALVDT":"2022-05-25","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7671,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.00831,"AVALU":"mg/L","BASE2":7.6952,"BASE":9.86452,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.3131,"PCHG2":17.06392,"CHG":-0.85621,"PCHG":-8.67968,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-10 00:32:46","ADY":882,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-127","SUBJID":"id-127","SITEID":"USA-15","AGE":57,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.37225,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 00:32:46","TRTEDTM":"2022-05-11 18:32:46","TRT01SDTM":"2019-05-12 00:32:46","TRT01EDTM":"2021-05-11 12:32:46","TRT02SDTM":"2021-05-11 12:32:46","TRT02EDTM":"2022-05-11 18:32:46","AP01SDTM":"2019-05-12 00:32:46","AP01EDTM":"2021-05-11 12:32:46","AP02SDTM":"2021-05-11 12:32:46","AP02EDTM":"2022-05-11 18:32:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-11","EOSDY":1096,"LSTALVDT":"2022-05-25","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":463,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.5909,"AVALU":"mg/L","BASE2":7.6952,"BASE":9.86452,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.89569,"PCHG2":11.63964,"CHG":-1.27362,"PCHG":-12.91111,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-01 00:32:46","ADY":965,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-127","SUBJID":"id-127","SITEID":"USA-15","AGE":57,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.37225,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 00:32:46","TRTEDTM":"2022-05-11 18:32:46","TRT01SDTM":"2019-05-12 00:32:46","TRT01EDTM":"2021-05-11 12:32:46","TRT02SDTM":"2021-05-11 12:32:46","TRT02EDTM":"2022-05-11 18:32:46","AP01SDTM":"2019-05-12 00:32:46","AP01EDTM":"2021-05-11 12:32:46","AP02SDTM":"2021-05-11 12:32:46","AP02EDTM":"2022-05-11 18:32:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-11","EOSDY":1096,"LSTALVDT":"2022-05-25","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8282,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.2823,"AVALU":"mg/L","BASE2":7.6952,"BASE":9.86452,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.5871,"PCHG2":7.62943,"CHG":-1.58221,"PCHG":-16.03943,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-14 00:32:46","ADY":1009,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-127","SUBJID":"id-127","SITEID":"USA-15","AGE":57,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.37225,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 00:32:46","TRTEDTM":"2022-05-11 18:32:46","TRT01SDTM":"2019-05-12 00:32:46","TRT01EDTM":"2021-05-11 12:32:46","TRT02SDTM":"2021-05-11 12:32:46","TRT02EDTM":"2022-05-11 18:32:46","AP01SDTM":"2019-05-12 00:32:46","AP01EDTM":"2021-05-11 12:32:46","AP02SDTM":"2021-05-11 12:32:46","AP02EDTM":"2022-05-11 18:32:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-11","EOSDY":1096,"LSTALVDT":"2022-05-25","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3042,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95972,"AVALU":"g/L","BASE2":2.95972,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-09 00:32:46","ADY":394,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-127","SUBJID":"id-127","SITEID":"USA-15","AGE":57,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.37225,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 00:32:46","TRTEDTM":"2022-05-11 18:32:46","TRT01SDTM":"2019-05-12 00:32:46","TRT01EDTM":"2021-05-11 12:32:46","TRT02SDTM":"2021-05-11 12:32:46","TRT02EDTM":"2022-05-11 18:32:46","AP01SDTM":"2019-05-12 00:32:46","AP01EDTM":"2021-05-11 12:32:46","AP02SDTM":"2021-05-11 12:32:46","AP02EDTM":"2022-05-11 18:32:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-11","EOSDY":1096,"LSTALVDT":"2022-05-25","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7190,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75503,"AVALU":"g/L","BASE2":2.95972,"BASE":2.75503,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.20469,"PCHG2":-6.91599,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-24 00:32:46","ADY":592,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-127","SUBJID":"id-127","SITEID":"USA-15","AGE":57,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.37225,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 00:32:46","TRTEDTM":"2022-05-11 18:32:46","TRT01SDTM":"2019-05-12 00:32:46","TRT01EDTM":"2021-05-11 12:32:46","TRT02SDTM":"2021-05-11 12:32:46","TRT02EDTM":"2022-05-11 18:32:46","AP01SDTM":"2019-05-12 00:32:46","AP01EDTM":"2021-05-11 12:32:46","AP02SDTM":"2021-05-11 12:32:46","AP02EDTM":"2022-05-11 18:32:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-11","EOSDY":1096,"LSTALVDT":"2022-05-25","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1463,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.68911,"AVALU":"g/L","BASE2":2.95972,"BASE":2.75503,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.27061,"PCHG2":-9.14309,"CHG":-0.06592,"PCHG":-2.39257,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-30 00:32:46","ADY":629,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-127","SUBJID":"id-127","SITEID":"USA-15","AGE":57,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.37225,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 00:32:46","TRTEDTM":"2022-05-11 18:32:46","TRT01SDTM":"2019-05-12 00:32:46","TRT01EDTM":"2021-05-11 12:32:46","TRT02SDTM":"2021-05-11 12:32:46","TRT02EDTM":"2022-05-11 18:32:46","AP01SDTM":"2019-05-12 00:32:46","AP01EDTM":"2021-05-11 12:32:46","AP02SDTM":"2021-05-11 12:32:46","AP02EDTM":"2022-05-11 18:32:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-11","EOSDY":1096,"LSTALVDT":"2022-05-25","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3734,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97336,"AVALU":"g/L","BASE2":2.95972,"BASE":2.75503,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01364,"PCHG2":0.46086,"CHG":0.21833,"PCHG":7.92494,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-27 00:32:46","ADY":716,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-127","SUBJID":"id-127","SITEID":"USA-15","AGE":57,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.37225,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 00:32:46","TRTEDTM":"2022-05-11 18:32:46","TRT01SDTM":"2019-05-12 00:32:46","TRT01EDTM":"2021-05-11 12:32:46","TRT02SDTM":"2021-05-11 12:32:46","TRT02EDTM":"2022-05-11 18:32:46","AP01SDTM":"2019-05-12 00:32:46","AP01EDTM":"2021-05-11 12:32:46","AP02SDTM":"2021-05-11 12:32:46","AP02EDTM":"2022-05-11 18:32:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-11","EOSDY":1096,"LSTALVDT":"2022-05-25","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6011,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.962,"AVALU":"g/L","BASE2":2.95972,"BASE":2.75503,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00228,"PCHG2":0.07698,"CHG":0.20697,"PCHG":7.51254,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-10 00:32:46","ADY":882,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-127","SUBJID":"id-127","SITEID":"USA-15","AGE":57,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.37225,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 00:32:46","TRTEDTM":"2022-05-11 18:32:46","TRT01SDTM":"2019-05-12 00:32:46","TRT01EDTM":"2021-05-11 12:32:46","TRT02SDTM":"2021-05-11 12:32:46","TRT02EDTM":"2022-05-11 18:32:46","AP01SDTM":"2019-05-12 00:32:46","AP01EDTM":"2021-05-11 12:32:46","AP02SDTM":"2021-05-11 12:32:46","AP02EDTM":"2022-05-11 18:32:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-11","EOSDY":1096,"LSTALVDT":"2022-05-25","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4159,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95999,"AVALU":"g/L","BASE2":2.95972,"BASE":2.75503,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.00027,"PCHG2":0.00919,"CHG":0.20497,"PCHG":7.43971,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-01-01 00:32:46","ADY":965,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-127","SUBJID":"id-127","SITEID":"USA-15","AGE":57,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"A: Drug X","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.37225,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-09","TRTSDTM":"2019-05-12 00:32:46","TRTEDTM":"2022-05-11 18:32:46","TRT01SDTM":"2019-05-12 00:32:46","TRT01EDTM":"2021-05-11 12:32:46","TRT02SDTM":"2021-05-11 12:32:46","TRT02EDTM":"2022-05-11 18:32:46","AP01SDTM":"2019-05-12 00:32:46","AP01EDTM":"2021-05-11 12:32:46","AP02SDTM":"2021-05-11 12:32:46","AP02EDTM":"2022-05-11 18:32:46","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-11","EOSDY":1096,"LSTALVDT":"2022-05-25","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7272,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85045,"AVALU":"g/L","BASE2":2.95972,"BASE":2.75503,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10927,"PCHG2":-3.69193,"CHG":0.09542,"PCHG":3.4636,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-02-14 00:32:46","ADY":1009,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-372","SUBJID":"id-372","SITEID":"USA-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.4481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-22 12:25:28","TRT01SDTM":"2020-01-22 12:25:28","AP01SDTM":"2020-01-22 12:25:28","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3198,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.73891,"AVALU":"U/L","BASE2":8.73891,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-14 12:25:28","ADY":23,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-372","SUBJID":"id-372","SITEID":"USA-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.4481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-22 12:25:28","TRT01SDTM":"2020-01-22 12:25:28","AP01SDTM":"2020-01-22 12:25:28","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6727,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.63251,"AVALU":"U/L","BASE2":8.73891,"BASE":15.63251,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":6.8936,"PCHG2":78.88405,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-20 12:25:28","ADY":150,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-372","SUBJID":"id-372","SITEID":"USA-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.4481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-22 12:25:28","TRT01SDTM":"2020-01-22 12:25:28","AP01SDTM":"2020-01-22 12:25:28","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3084,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.60078,"AVALU":"U/L","BASE2":8.73891,"BASE":15.63251,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.86188,"PCHG2":135.73644,"CHG":4.96828,"PCHG":31.7817,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-20 12:25:28","ADY":395,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-372","SUBJID":"id-372","SITEID":"USA-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.4481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-22 12:25:28","TRT01SDTM":"2020-01-22 12:25:28","AP01SDTM":"2020-01-22 12:25:28","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1164,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.75486,"AVALU":"U/L","BASE2":8.73891,"BASE":15.63251,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.01595,"PCHG2":114.61336,"CHG":3.12235,"PCHG":19.97345,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-04 12:25:28","ADY":407,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-372","SUBJID":"id-372","SITEID":"USA-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.4481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-22 12:25:28","TRT01SDTM":"2020-01-22 12:25:28","AP01SDTM":"2020-01-22 12:25:28","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5125,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.43795,"AVALU":"U/L","BASE2":8.73891,"BASE":15.63251,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.69904,"PCHG2":30.88538,"CHG":-4.19456,"PCHG":-26.83228,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-29 12:25:28","ADY":463,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-372","SUBJID":"id-372","SITEID":"USA-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.4481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-22 12:25:28","TRT01SDTM":"2020-01-22 12:25:28","AP01SDTM":"2020-01-22 12:25:28","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2407,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.00441,"AVALU":"U/L","BASE2":8.73891,"BASE":15.63251,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":21.2655,"PCHG2":243.34285,"CHG":14.3719,"PCHG":91.93598,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-26 12:25:28","ADY":613,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-372","SUBJID":"id-372","SITEID":"USA-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.4481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-22 12:25:28","TRT01SDTM":"2020-01-22 12:25:28","AP01SDTM":"2020-01-22 12:25:28","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8258,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.42494,"AVALU":"U/L","BASE2":8.73891,"BASE":15.63251,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":21.68603,"PCHG2":248.15504,"CHG":14.79243,"PCHG":94.6261,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-29 12:25:28","ADY":677,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-372","SUBJID":"id-372","SITEID":"USA-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.4481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-22 12:25:28","TRT01SDTM":"2020-01-22 12:25:28","AP01SDTM":"2020-01-22 12:25:28","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3336,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.29964,"AVALU":"mg/L","BASE2":10.29964,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"","ATOXGR":"2","BTOXGR":"-3","ADTM":"2020-02-14 12:25:28","ADY":23,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-372","SUBJID":"id-372","SITEID":"USA-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.4481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-22 12:25:28","TRT01SDTM":"2020-01-22 12:25:28","AP01SDTM":"2020-01-22 12:25:28","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6262,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.9069,"AVALU":"mg/L","BASE2":10.29964,"BASE":7.9069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.39274,"PCHG2":-23.23131,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-3","BTOXGR":"-3","ADTM":"2020-06-20 12:25:28","ADY":150,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-372","SUBJID":"id-372","SITEID":"USA-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.4481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-22 12:25:28","TRT01SDTM":"2020-01-22 12:25:28","AP01SDTM":"2020-01-22 12:25:28","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7220,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.25787,"AVALU":"mg/L","BASE2":10.29964,"BASE":7.9069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.04177,"PCHG2":-10.11465,"CHG":1.35097,"PCHG":17.08595,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-02-20 12:25:28","ADY":395,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-372","SUBJID":"id-372","SITEID":"USA-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.4481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-22 12:25:28","TRT01SDTM":"2020-01-22 12:25:28","AP01SDTM":"2020-01-22 12:25:28","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5872,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.78032,"AVALU":"mg/L","BASE2":10.29964,"BASE":7.9069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.51932,"PCHG2":-14.75119,"CHG":0.87342,"PCHG":11.04633,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-03-04 12:25:28","ADY":407,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-372","SUBJID":"id-372","SITEID":"USA-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.4481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-22 12:25:28","TRT01SDTM":"2020-01-22 12:25:28","AP01SDTM":"2020-01-22 12:25:28","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8146,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.47391,"AVALU":"mg/L","BASE2":10.29964,"BASE":7.9069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.82573,"PCHG2":-17.72614,"CHG":0.56701,"PCHG":7.17112,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-04-29 12:25:28","ADY":463,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-372","SUBJID":"id-372","SITEID":"USA-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.4481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-22 12:25:28","TRT01SDTM":"2020-01-22 12:25:28","AP01SDTM":"2020-01-22 12:25:28","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3303,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.79245,"AVALU":"mg/L","BASE2":10.29964,"BASE":7.9069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.50719,"PCHG2":-24.34253,"CHG":-0.11445,"PCHG":-1.44748,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"LOW to LOW","ATOXGR":"-4","BTOXGR":"-3","ADTM":"2021-09-26 12:25:28","ADY":613,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-372","SUBJID":"id-372","SITEID":"USA-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.4481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-22 12:25:28","TRT01SDTM":"2020-01-22 12:25:28","AP01SDTM":"2020-01-22 12:25:28","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3679,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.88063,"AVALU":"mg/L","BASE2":10.29964,"BASE":7.9069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.41901,"PCHG2":-13.7773,"CHG":0.97373,"PCHG":12.31494,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-3","ADTM":"2021-11-29 12:25:28","ADY":677,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"3","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-372","SUBJID":"id-372","SITEID":"USA-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.4481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-22 12:25:28","TRT01SDTM":"2020-01-22 12:25:28","AP01SDTM":"2020-01-22 12:25:28","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1598,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83209,"AVALU":"g/L","BASE2":2.83209,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-14 12:25:28","ADY":23,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-372","SUBJID":"id-372","SITEID":"USA-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.4481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-22 12:25:28","TRT01SDTM":"2020-01-22 12:25:28","AP01SDTM":"2020-01-22 12:25:28","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5378,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90086,"AVALU":"g/L","BASE2":2.83209,"BASE":2.90086,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.06877,"PCHG2":2.42835,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-20 12:25:28","ADY":150,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-372","SUBJID":"id-372","SITEID":"USA-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.4481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-22 12:25:28","TRT01SDTM":"2020-01-22 12:25:28","AP01SDTM":"2020-01-22 12:25:28","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6524,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89718,"AVALU":"g/L","BASE2":2.83209,"BASE":2.90086,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06509,"PCHG2":2.29827,"CHG":-0.00368,"PCHG":-0.127,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-20 12:25:28","ADY":395,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-372","SUBJID":"id-372","SITEID":"USA-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.4481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-22 12:25:28","TRT01SDTM":"2020-01-22 12:25:28","AP01SDTM":"2020-01-22 12:25:28","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4188,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8946,"AVALU":"g/L","BASE2":2.83209,"BASE":2.90086,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06252,"PCHG2":2.20744,"CHG":-0.00626,"PCHG":-0.21567,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-04 12:25:28","ADY":407,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-372","SUBJID":"id-372","SITEID":"USA-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.4481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-22 12:25:28","TRT01SDTM":"2020-01-22 12:25:28","AP01SDTM":"2020-01-22 12:25:28","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7639,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03965,"AVALU":"g/L","BASE2":2.83209,"BASE":2.90086,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.20756,"PCHG2":7.32883,"CHG":0.13879,"PCHG":4.7843,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"3","BTOXGR":"0","ADTM":"2021-04-29 12:25:28","ADY":463,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-372","SUBJID":"id-372","SITEID":"USA-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.4481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-22 12:25:28","TRT01SDTM":"2020-01-22 12:25:28","AP01SDTM":"2020-01-22 12:25:28","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5827,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85163,"AVALU":"g/L","BASE2":2.83209,"BASE":2.90086,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01954,"PCHG2":0.68985,"CHG":-0.04924,"PCHG":-1.69728,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-26 12:25:28","ADY":613,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-15-id-372","SUBJID":"id-372","SITEID":"USA-15","AGE":27,"AGEU":"YEARS","SEX":"M","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-15","INVNAM":"Dr. USA-15 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"C: Combination","TRT02A":"A: Drug X","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":3.4481,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-20","TRTSDTM":"2020-01-22 12:25:28","TRT01SDTM":"2020-01-22 12:25:28","AP01SDTM":"2020-01-22 12:25:28","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1201,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79961,"AVALU":"g/L","BASE2":2.83209,"BASE":2.90086,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03247,"PCHG2":-1.14662,"CHG":-0.10125,"PCHG":-3.49022,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-29 12:25:28","ADY":677,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-142","SUBJID":"id-142","SITEID":"USA-17","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":8.8187,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-13","TRTSDTM":"2019-05-14 12:56:10","TRTEDTM":"2022-05-14 06:56:10","TRT01SDTM":"2019-05-14 12:56:10","TRT01EDTM":"2021-05-14 00:56:10","TRT02SDTM":"2021-05-14 00:56:10","TRT02EDTM":"2022-05-14 06:56:10","AP01SDTM":"2019-05-14 12:56:10","AP01EDTM":"2021-05-14 00:56:10","AP02SDTM":"2021-05-14 00:56:10","AP02EDTM":"2022-05-14 06:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-14","EOSDY":1096,"LSTALVDT":"2022-06-12","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8246,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.46638,"AVALU":"U/L","BASE2":15.46638,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-31 12:56:10","ADY":231,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-142","SUBJID":"id-142","SITEID":"USA-17","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":8.8187,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-13","TRTSDTM":"2019-05-14 12:56:10","TRTEDTM":"2022-05-14 06:56:10","TRT01SDTM":"2019-05-14 12:56:10","TRT01EDTM":"2021-05-14 00:56:10","TRT02SDTM":"2021-05-14 00:56:10","TRT02EDTM":"2022-05-14 06:56:10","AP01SDTM":"2019-05-14 12:56:10","AP01EDTM":"2021-05-14 00:56:10","AP02SDTM":"2021-05-14 00:56:10","AP02EDTM":"2022-05-14 06:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-14","EOSDY":1096,"LSTALVDT":"2022-06-12","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3833,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":41.90577,"AVALU":"U/L","BASE2":15.46638,"BASE":41.90577,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":26.43938,"PCHG2":170.94742,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-07 12:56:10","ADY":420,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-142","SUBJID":"id-142","SITEID":"USA-17","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":8.8187,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-13","TRTSDTM":"2019-05-14 12:56:10","TRTEDTM":"2022-05-14 06:56:10","TRT01SDTM":"2019-05-14 12:56:10","TRT01EDTM":"2021-05-14 00:56:10","TRT02SDTM":"2021-05-14 00:56:10","TRT02EDTM":"2022-05-14 06:56:10","AP01SDTM":"2019-05-14 12:56:10","AP01EDTM":"2021-05-14 00:56:10","AP02SDTM":"2021-05-14 00:56:10","AP02EDTM":"2022-05-14 06:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-14","EOSDY":1096,"LSTALVDT":"2022-06-12","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2065,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.91212,"AVALU":"U/L","BASE2":15.46638,"BASE":41.90577,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.44573,"PCHG2":48.1414,"CHG":-18.99365,"PCHG":-45.32467,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-29 12:56:10","ADY":504,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-142","SUBJID":"id-142","SITEID":"USA-17","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":8.8187,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-13","TRTSDTM":"2019-05-14 12:56:10","TRTEDTM":"2022-05-14 06:56:10","TRT01SDTM":"2019-05-14 12:56:10","TRT01EDTM":"2021-05-14 00:56:10","TRT02SDTM":"2021-05-14 00:56:10","TRT02EDTM":"2022-05-14 06:56:10","AP01SDTM":"2019-05-14 12:56:10","AP01EDTM":"2021-05-14 00:56:10","AP02SDTM":"2021-05-14 00:56:10","AP02EDTM":"2022-05-14 06:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-14","EOSDY":1096,"LSTALVDT":"2022-06-12","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5978,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":32.19589,"AVALU":"U/L","BASE2":15.46638,"BASE":41.90577,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.72951,"PCHG2":108.1669,"CHG":-9.70988,"PCHG":-23.17074,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-11 12:56:10","ADY":547,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-142","SUBJID":"id-142","SITEID":"USA-17","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":8.8187,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-13","TRTSDTM":"2019-05-14 12:56:10","TRTEDTM":"2022-05-14 06:56:10","TRT01SDTM":"2019-05-14 12:56:10","TRT01EDTM":"2021-05-14 00:56:10","TRT02SDTM":"2021-05-14 00:56:10","TRT02EDTM":"2022-05-14 06:56:10","AP01SDTM":"2019-05-14 12:56:10","AP01EDTM":"2021-05-14 00:56:10","AP02SDTM":"2021-05-14 00:56:10","AP02EDTM":"2022-05-14 06:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-14","EOSDY":1096,"LSTALVDT":"2022-06-12","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1886,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.879,"AVALU":"U/L","BASE2":15.46638,"BASE":41.90577,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.41262,"PCHG2":34.99603,"CHG":-21.02676,"PCHG":-50.1763,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-25 12:56:10","ADY":653,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-142","SUBJID":"id-142","SITEID":"USA-17","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":8.8187,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-13","TRTSDTM":"2019-05-14 12:56:10","TRTEDTM":"2022-05-14 06:56:10","TRT01SDTM":"2019-05-14 12:56:10","TRT01EDTM":"2021-05-14 00:56:10","TRT02SDTM":"2021-05-14 00:56:10","TRT02EDTM":"2022-05-14 06:56:10","AP01SDTM":"2019-05-14 12:56:10","AP01EDTM":"2021-05-14 00:56:10","AP02SDTM":"2021-05-14 00:56:10","AP02EDTM":"2022-05-14 06:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-14","EOSDY":1096,"LSTALVDT":"2022-06-12","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5567,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.15172,"AVALU":"U/L","BASE2":15.46638,"BASE":41.90577,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":6.68534,"PCHG2":43.22498,"CHG":-19.75404,"PCHG":-47.1392,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-08 12:56:10","ADY":939,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-142","SUBJID":"id-142","SITEID":"USA-17","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":8.8187,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-13","TRTSDTM":"2019-05-14 12:56:10","TRTEDTM":"2022-05-14 06:56:10","TRT01SDTM":"2019-05-14 12:56:10","TRT01EDTM":"2021-05-14 00:56:10","TRT02SDTM":"2021-05-14 00:56:10","TRT02EDTM":"2022-05-14 06:56:10","AP01SDTM":"2019-05-14 12:56:10","AP01EDTM":"2021-05-14 00:56:10","AP02SDTM":"2021-05-14 00:56:10","AP02EDTM":"2022-05-14 06:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-14","EOSDY":1096,"LSTALVDT":"2022-06-12","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3591,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.77741,"AVALU":"U/L","BASE2":15.46638,"BASE":41.90577,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.31103,"PCHG2":53.73609,"CHG":-18.12835,"PCHG":-43.25981,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-04 12:56:10","ADY":1025,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-142","SUBJID":"id-142","SITEID":"USA-17","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":8.8187,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-13","TRTSDTM":"2019-05-14 12:56:10","TRTEDTM":"2022-05-14 06:56:10","TRT01SDTM":"2019-05-14 12:56:10","TRT01EDTM":"2021-05-14 00:56:10","TRT02SDTM":"2021-05-14 00:56:10","TRT02EDTM":"2022-05-14 06:56:10","AP01SDTM":"2019-05-14 12:56:10","AP01EDTM":"2021-05-14 00:56:10","AP02SDTM":"2021-05-14 00:56:10","AP02EDTM":"2022-05-14 06:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-14","EOSDY":1096,"LSTALVDT":"2022-06-12","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3510,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.25371,"AVALU":"mg/L","BASE2":9.25371,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-31 12:56:10","ADY":231,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-142","SUBJID":"id-142","SITEID":"USA-17","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":8.8187,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-13","TRTSDTM":"2019-05-14 12:56:10","TRTEDTM":"2022-05-14 06:56:10","TRT01SDTM":"2019-05-14 12:56:10","TRT01EDTM":"2021-05-14 00:56:10","TRT02SDTM":"2021-05-14 00:56:10","TRT02EDTM":"2022-05-14 06:56:10","AP01SDTM":"2019-05-14 12:56:10","AP01EDTM":"2021-05-14 00:56:10","AP02SDTM":"2021-05-14 00:56:10","AP02EDTM":"2022-05-14 06:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-14","EOSDY":1096,"LSTALVDT":"2022-06-12","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4820,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.27127,"AVALU":"mg/L","BASE2":9.25371,"BASE":9.27127,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.01755,"PCHG2":0.18969,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-07 12:56:10","ADY":420,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-142","SUBJID":"id-142","SITEID":"USA-17","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":8.8187,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-13","TRTSDTM":"2019-05-14 12:56:10","TRTEDTM":"2022-05-14 06:56:10","TRT01SDTM":"2019-05-14 12:56:10","TRT01EDTM":"2021-05-14 00:56:10","TRT02SDTM":"2021-05-14 00:56:10","TRT02EDTM":"2022-05-14 06:56:10","AP01SDTM":"2019-05-14 12:56:10","AP01EDTM":"2021-05-14 00:56:10","AP02SDTM":"2021-05-14 00:56:10","AP02EDTM":"2022-05-14 06:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-14","EOSDY":1096,"LSTALVDT":"2022-06-12","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4289,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.75377,"AVALU":"mg/L","BASE2":9.25371,"BASE":9.27127,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.50006,"PCHG2":16.21031,"CHG":1.4825,"PCHG":15.99028,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2020-09-29 12:56:10","ADY":504,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-142","SUBJID":"id-142","SITEID":"USA-17","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":8.8187,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-13","TRTSDTM":"2019-05-14 12:56:10","TRTEDTM":"2022-05-14 06:56:10","TRT01SDTM":"2019-05-14 12:56:10","TRT01EDTM":"2021-05-14 00:56:10","TRT02SDTM":"2021-05-14 00:56:10","TRT02EDTM":"2022-05-14 06:56:10","AP01SDTM":"2019-05-14 12:56:10","AP01EDTM":"2021-05-14 00:56:10","AP02SDTM":"2021-05-14 00:56:10","AP02EDTM":"2022-05-14 06:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-14","EOSDY":1096,"LSTALVDT":"2022-06-12","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7617,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.28847,"AVALU":"mg/L","BASE2":9.25371,"BASE":9.27127,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03476,"PCHG2":0.37559,"CHG":0.0172,"PCHG":0.18554,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-11 12:56:10","ADY":547,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-142","SUBJID":"id-142","SITEID":"USA-17","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":8.8187,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-13","TRTSDTM":"2019-05-14 12:56:10","TRTEDTM":"2022-05-14 06:56:10","TRT01SDTM":"2019-05-14 12:56:10","TRT01EDTM":"2021-05-14 00:56:10","TRT02SDTM":"2021-05-14 00:56:10","TRT02EDTM":"2022-05-14 06:56:10","AP01SDTM":"2019-05-14 12:56:10","AP01EDTM":"2021-05-14 00:56:10","AP02SDTM":"2021-05-14 00:56:10","AP02EDTM":"2022-05-14 06:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-14","EOSDY":1096,"LSTALVDT":"2022-06-12","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5291,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.99951,"AVALU":"mg/L","BASE2":9.25371,"BASE":9.27127,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.7458,"PCHG2":18.86595,"CHG":1.72825,"PCHG":18.6409,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-02-25 12:56:10","ADY":653,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-142","SUBJID":"id-142","SITEID":"USA-17","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":8.8187,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-13","TRTSDTM":"2019-05-14 12:56:10","TRTEDTM":"2022-05-14 06:56:10","TRT01SDTM":"2019-05-14 12:56:10","TRT01EDTM":"2021-05-14 00:56:10","TRT02SDTM":"2021-05-14 00:56:10","TRT02EDTM":"2022-05-14 06:56:10","AP01SDTM":"2019-05-14 12:56:10","AP01EDTM":"2021-05-14 00:56:10","AP02SDTM":"2021-05-14 00:56:10","AP02EDTM":"2022-05-14 06:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-14","EOSDY":1096,"LSTALVDT":"2022-06-12","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2021,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.70432,"AVALU":"mg/L","BASE2":9.25371,"BASE":9.27127,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.54939,"PCHG2":-5.93699,"CHG":-0.56695,"PCHG":-6.11508,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-08 12:56:10","ADY":939,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-142","SUBJID":"id-142","SITEID":"USA-17","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":8.8187,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-13","TRTSDTM":"2019-05-14 12:56:10","TRTEDTM":"2022-05-14 06:56:10","TRT01SDTM":"2019-05-14 12:56:10","TRT01EDTM":"2021-05-14 00:56:10","TRT02SDTM":"2021-05-14 00:56:10","TRT02EDTM":"2022-05-14 06:56:10","AP01SDTM":"2019-05-14 12:56:10","AP01EDTM":"2021-05-14 00:56:10","AP02SDTM":"2021-05-14 00:56:10","AP02EDTM":"2022-05-14 06:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-14","EOSDY":1096,"LSTALVDT":"2022-06-12","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5021,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.6015,"AVALU":"mg/L","BASE2":9.25371,"BASE":9.27127,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.65222,"PCHG2":-7.04815,"CHG":-0.66977,"PCHG":-7.22414,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-04 12:56:10","ADY":1025,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-142","SUBJID":"id-142","SITEID":"USA-17","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":8.8187,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-13","TRTSDTM":"2019-05-14 12:56:10","TRTEDTM":"2022-05-14 06:56:10","TRT01SDTM":"2019-05-14 12:56:10","TRT01EDTM":"2021-05-14 00:56:10","TRT02SDTM":"2021-05-14 00:56:10","TRT02EDTM":"2022-05-14 06:56:10","AP01SDTM":"2019-05-14 12:56:10","AP01EDTM":"2021-05-14 00:56:10","AP02SDTM":"2021-05-14 00:56:10","AP02EDTM":"2022-05-14 06:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-14","EOSDY":1096,"LSTALVDT":"2022-06-12","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7345,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.972,"AVALU":"g/L","BASE2":2.972,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-31 12:56:10","ADY":231,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-142","SUBJID":"id-142","SITEID":"USA-17","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":8.8187,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-13","TRTSDTM":"2019-05-14 12:56:10","TRTEDTM":"2022-05-14 06:56:10","TRT01SDTM":"2019-05-14 12:56:10","TRT01EDTM":"2021-05-14 00:56:10","TRT02SDTM":"2021-05-14 00:56:10","TRT02EDTM":"2022-05-14 06:56:10","AP01SDTM":"2019-05-14 12:56:10","AP01EDTM":"2021-05-14 00:56:10","AP02SDTM":"2021-05-14 00:56:10","AP02EDTM":"2022-05-14 06:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-14","EOSDY":1096,"LSTALVDT":"2022-06-12","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2519,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89363,"AVALU":"g/L","BASE2":2.972,"BASE":2.89363,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.07837,"PCHG2":-2.63711,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-07 12:56:10","ADY":420,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-142","SUBJID":"id-142","SITEID":"USA-17","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":8.8187,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-13","TRTSDTM":"2019-05-14 12:56:10","TRTEDTM":"2022-05-14 06:56:10","TRT01SDTM":"2019-05-14 12:56:10","TRT01EDTM":"2021-05-14 00:56:10","TRT02SDTM":"2021-05-14 00:56:10","TRT02EDTM":"2022-05-14 06:56:10","AP01SDTM":"2019-05-14 12:56:10","AP01EDTM":"2021-05-14 00:56:10","AP02SDTM":"2021-05-14 00:56:10","AP02EDTM":"2022-05-14 06:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-14","EOSDY":1096,"LSTALVDT":"2022-06-12","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6023,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88376,"AVALU":"g/L","BASE2":2.972,"BASE":2.89363,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08824,"PCHG2":-2.969,"CHG":-0.00986,"PCHG":-0.34088,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-29 12:56:10","ADY":504,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-142","SUBJID":"id-142","SITEID":"USA-17","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":8.8187,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-13","TRTSDTM":"2019-05-14 12:56:10","TRTEDTM":"2022-05-14 06:56:10","TRT01SDTM":"2019-05-14 12:56:10","TRT01EDTM":"2021-05-14 00:56:10","TRT02SDTM":"2021-05-14 00:56:10","TRT02EDTM":"2022-05-14 06:56:10","AP01SDTM":"2019-05-14 12:56:10","AP01EDTM":"2021-05-14 00:56:10","AP02SDTM":"2021-05-14 00:56:10","AP02EDTM":"2022-05-14 06:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-14","EOSDY":1096,"LSTALVDT":"2022-06-12","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":125,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86779,"AVALU":"g/L","BASE2":2.972,"BASE":2.89363,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10421,"PCHG2":-3.50646,"CHG":-0.02584,"PCHG":-0.8929,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-11 12:56:10","ADY":547,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-142","SUBJID":"id-142","SITEID":"USA-17","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":8.8187,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-13","TRTSDTM":"2019-05-14 12:56:10","TRTEDTM":"2022-05-14 06:56:10","TRT01SDTM":"2019-05-14 12:56:10","TRT01EDTM":"2021-05-14 00:56:10","TRT02SDTM":"2021-05-14 00:56:10","TRT02EDTM":"2022-05-14 06:56:10","AP01SDTM":"2019-05-14 12:56:10","AP01EDTM":"2021-05-14 00:56:10","AP02SDTM":"2021-05-14 00:56:10","AP02EDTM":"2022-05-14 06:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-14","EOSDY":1096,"LSTALVDT":"2022-06-12","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1547,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87736,"AVALU":"g/L","BASE2":2.972,"BASE":2.89363,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.09465,"PCHG2":-3.18456,"CHG":-0.01627,"PCHG":-0.56228,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-25 12:56:10","ADY":653,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-142","SUBJID":"id-142","SITEID":"USA-17","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":8.8187,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-13","TRTSDTM":"2019-05-14 12:56:10","TRTEDTM":"2022-05-14 06:56:10","TRT01SDTM":"2019-05-14 12:56:10","TRT01EDTM":"2021-05-14 00:56:10","TRT02SDTM":"2021-05-14 00:56:10","TRT02EDTM":"2022-05-14 06:56:10","AP01SDTM":"2019-05-14 12:56:10","AP01EDTM":"2021-05-14 00:56:10","AP02SDTM":"2021-05-14 00:56:10","AP02EDTM":"2022-05-14 06:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-14","EOSDY":1096,"LSTALVDT":"2022-06-12","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7437,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9169,"AVALU":"g/L","BASE2":2.972,"BASE":2.89363,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0551,"PCHG2":-1.85398,"CHG":0.02327,"PCHG":0.80434,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-08 12:56:10","ADY":939,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-142","SUBJID":"id-142","SITEID":"USA-17","AGE":31,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":8.8187,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-05-13","TRTSDTM":"2019-05-14 12:56:10","TRTEDTM":"2022-05-14 06:56:10","TRT01SDTM":"2019-05-14 12:56:10","TRT01EDTM":"2021-05-14 00:56:10","TRT02SDTM":"2021-05-14 00:56:10","TRT02EDTM":"2022-05-14 06:56:10","AP01SDTM":"2019-05-14 12:56:10","AP01EDTM":"2021-05-14 00:56:10","AP02SDTM":"2021-05-14 00:56:10","AP02EDTM":"2022-05-14 06:56:10","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-05-14","EOSDY":1096,"LSTALVDT":"2022-06-12","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2770,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89626,"AVALU":"g/L","BASE2":2.972,"BASE":2.89363,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07574,"PCHG2":-2.5484,"CHG":0.00264,"PCHG":0.09111,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-04 12:56:10","ADY":1025,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-3","SUBJID":"id-3","SITEID":"USA-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":5.39748,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-25","TRTSDTM":"2020-01-26 15:30:59","TRT01SDTM":"2020-01-26 15:30:59","AP01SDTM":"2020-01-26 15:30:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8328,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.02012,"AVALU":"U/L","BASE2":22.02012,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-01 15:30:59","ADY":66,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-3","SUBJID":"id-3","SITEID":"USA-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":5.39748,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-25","TRTSDTM":"2020-01-26 15:30:59","TRT01SDTM":"2020-01-26 15:30:59","AP01SDTM":"2020-01-26 15:30:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7753,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.69991,"AVALU":"U/L","BASE2":22.02012,"BASE":13.69991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-8.32021,"PCHG2":-37.78459,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-24 15:30:59","ADY":150,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-3","SUBJID":"id-3","SITEID":"USA-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":5.39748,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-25","TRTSDTM":"2020-01-26 15:30:59","TRT01SDTM":"2020-01-26 15:30:59","AP01SDTM":"2020-01-26 15:30:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1152,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.36115,"AVALU":"U/L","BASE2":22.02012,"BASE":13.69991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.65896,"PCHG2":-62.02947,"CHG":-5.33875,"PCHG":-38.96926,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-09 15:30:59","ADY":227,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-3","SUBJID":"id-3","SITEID":"USA-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":5.39748,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-25","TRTSDTM":"2020-01-26 15:30:59","TRT01SDTM":"2020-01-26 15:30:59","AP01SDTM":"2020-01-26 15:30:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5972,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.27615,"AVALU":"U/L","BASE2":22.02012,"BASE":13.69991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.74396,"PCHG2":-35.16768,"CHG":0.57625,"PCHG":4.20621,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-21 15:30:59","ADY":269,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-3","SUBJID":"id-3","SITEID":"USA-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":5.39748,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-25","TRTSDTM":"2020-01-26 15:30:59","TRT01SDTM":"2020-01-26 15:30:59","AP01SDTM":"2020-01-26 15:30:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7458,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.20545,"AVALU":"U/L","BASE2":22.02012,"BASE":13.69991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":3.18533,"PCHG2":14.46554,"CHG":11.50554,"PCHG":83.98262,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-15 15:30:59","ADY":294,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-3","SUBJID":"id-3","SITEID":"USA-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":5.39748,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-25","TRTSDTM":"2020-01-26 15:30:59","TRT01SDTM":"2020-01-26 15:30:59","AP01SDTM":"2020-01-26 15:30:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2856,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.32386,"AVALU":"U/L","BASE2":22.02012,"BASE":13.69991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.69625,"PCHG2":-7.7032,"CHG":6.62396,"PCHG":48.35039,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-28 15:30:59","ADY":399,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-3","SUBJID":"id-3","SITEID":"USA-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":5.39748,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-25","TRTSDTM":"2020-01-26 15:30:59","TRT01SDTM":"2020-01-26 15:30:59","AP01SDTM":"2020-01-26 15:30:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7936,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.37707,"AVALU":"U/L","BASE2":22.02012,"BASE":13.69991,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.35695,"PCHG2":1.62102,"CHG":8.67716,"PCHG":63.33738,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-05 15:30:59","ADY":465,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-3","SUBJID":"id-3","SITEID":"USA-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":5.39748,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-25","TRTSDTM":"2020-01-26 15:30:59","TRT01SDTM":"2020-01-26 15:30:59","AP01SDTM":"2020-01-26 15:30:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5289,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.65324,"AVALU":"mg/L","BASE2":9.65324,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-01 15:30:59","ADY":66,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-3","SUBJID":"id-3","SITEID":"USA-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":5.39748,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-25","TRTSDTM":"2020-01-26 15:30:59","TRT01SDTM":"2020-01-26 15:30:59","AP01SDTM":"2020-01-26 15:30:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2211,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.50836,"AVALU":"mg/L","BASE2":9.65324,"BASE":8.50836,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.14488,"PCHG2":-11.86007,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-24 15:30:59","ADY":150,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-3","SUBJID":"id-3","SITEID":"USA-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":5.39748,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-25","TRTSDTM":"2020-01-26 15:30:59","TRT01SDTM":"2020-01-26 15:30:59","AP01SDTM":"2020-01-26 15:30:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":761,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.10124,"AVALU":"mg/L","BASE2":9.65324,"BASE":8.50836,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.552,"PCHG2":-16.07748,"CHG":-0.40712,"PCHG":-4.7849,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-09 15:30:59","ADY":227,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-3","SUBJID":"id-3","SITEID":"USA-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":5.39748,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-25","TRTSDTM":"2020-01-26 15:30:59","TRT01SDTM":"2020-01-26 15:30:59","AP01SDTM":"2020-01-26 15:30:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4023,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.35461,"AVALU":"mg/L","BASE2":9.65324,"BASE":8.50836,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.29864,"PCHG2":-13.45285,"CHG":-0.15375,"PCHG":-1.8071,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-21 15:30:59","ADY":269,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-3","SUBJID":"id-3","SITEID":"USA-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":5.39748,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-25","TRTSDTM":"2020-01-26 15:30:59","TRT01SDTM":"2020-01-26 15:30:59","AP01SDTM":"2020-01-26 15:30:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5793,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.61319,"AVALU":"mg/L","BASE2":9.65324,"BASE":8.50836,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04005,"PCHG2":-0.41487,"CHG":1.10483,"PCHG":12.98526,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-15 15:30:59","ADY":294,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-3","SUBJID":"id-3","SITEID":"USA-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":5.39748,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-25","TRTSDTM":"2020-01-26 15:30:59","TRT01SDTM":"2020-01-26 15:30:59","AP01SDTM":"2020-01-26 15:30:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7016,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.06846,"AVALU":"mg/L","BASE2":9.65324,"BASE":8.50836,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.58479,"PCHG2":-26.77634,"CHG":-1.4399,"PCHG":-16.9234,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-02-28 15:30:59","ADY":399,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-3","SUBJID":"id-3","SITEID":"USA-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":5.39748,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-25","TRTSDTM":"2020-01-26 15:30:59","TRT01SDTM":"2020-01-26 15:30:59","AP01SDTM":"2020-01-26 15:30:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6250,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.29178,"AVALU":"mg/L","BASE2":9.65324,"BASE":8.50836,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.36147,"PCHG2":-3.7445,"CHG":0.78342,"PCHG":9.20759,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-05 15:30:59","ADY":465,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-3","SUBJID":"id-3","SITEID":"USA-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":5.39748,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-25","TRTSDTM":"2020-01-26 15:30:59","TRT01SDTM":"2020-01-26 15:30:59","AP01SDTM":"2020-01-26 15:30:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4868,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80848,"AVALU":"g/L","BASE2":2.80848,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-01 15:30:59","ADY":66,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-3","SUBJID":"id-3","SITEID":"USA-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":5.39748,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-25","TRTSDTM":"2020-01-26 15:30:59","TRT01SDTM":"2020-01-26 15:30:59","AP01SDTM":"2020-01-26 15:30:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":521,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96184,"AVALU":"g/L","BASE2":2.80848,"BASE":2.96184,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.15336,"PCHG2":5.46064,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-24 15:30:59","ADY":150,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-3","SUBJID":"id-3","SITEID":"USA-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":5.39748,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-25","TRTSDTM":"2020-01-26 15:30:59","TRT01SDTM":"2020-01-26 15:30:59","AP01SDTM":"2020-01-26 15:30:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4062,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81915,"AVALU":"g/L","BASE2":2.80848,"BASE":2.96184,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01067,"PCHG2":0.37997,"CHG":-0.14269,"PCHG":-4.8176,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-09 15:30:59","ADY":227,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-3","SUBJID":"id-3","SITEID":"USA-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":5.39748,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-25","TRTSDTM":"2020-01-26 15:30:59","TRT01SDTM":"2020-01-26 15:30:59","AP01SDTM":"2020-01-26 15:30:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":714,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94247,"AVALU":"g/L","BASE2":2.80848,"BASE":2.96184,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.13399,"PCHG2":4.77091,"CHG":-0.01937,"PCHG":-0.65401,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-10-21 15:30:59","ADY":269,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-3","SUBJID":"id-3","SITEID":"USA-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":5.39748,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-25","TRTSDTM":"2020-01-26 15:30:59","TRT01SDTM":"2020-01-26 15:30:59","AP01SDTM":"2020-01-26 15:30:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7351,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.99684,"AVALU":"g/L","BASE2":2.80848,"BASE":2.96184,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.18836,"PCHG2":6.70682,"CHG":0.035,"PCHG":1.18165,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-11-15 15:30:59","ADY":294,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-3","SUBJID":"id-3","SITEID":"USA-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":5.39748,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-25","TRTSDTM":"2020-01-26 15:30:59","TRT01SDTM":"2020-01-26 15:30:59","AP01SDTM":"2020-01-26 15:30:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3567,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.67511,"AVALU":"g/L","BASE2":2.80848,"BASE":2.96184,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.13338,"PCHG2":-4.74903,"CHG":-0.28674,"PCHG":-9.68102,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-28 15:30:59","ADY":399,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-17-id-3","SUBJID":"id-3","SITEID":"USA-17","AGE":36,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":" NOT REPORTED","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-17","INVNAM":"Dr. USA-17 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":5.39748,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-01-25","TRTSDTM":"2020-01-26 15:30:59","TRT01SDTM":"2020-01-26 15:30:59","AP01SDTM":"2020-01-26 15:30:59","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3392,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.03509,"AVALU":"g/L","BASE2":2.80848,"BASE":2.96184,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.22661,"PCHG2":8.06876,"CHG":0.07325,"PCHG":2.47307,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-05-05 15:30:59","ADY":465,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-19-id-58","SUBJID":"id-58","SITEID":"USA-19","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-19","INVNAM":"Dr. USA-19 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.54605,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 20:26:34","TRTEDTM":"2023-11-01 14:26:34","TRT01SDTM":"2020-10-31 20:26:34","TRT01EDTM":"2022-11-01 08:26:34","TRT02SDTM":"2022-11-01 08:26:34","TRT02EDTM":"2023-11-01 14:26:34","AP01SDTM":"2020-10-31 20:26:34","AP01EDTM":"2022-11-01 08:26:34","AP02SDTM":"2022-11-01 08:26:34","AP02EDTM":"2023-11-01 14:26:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-17","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1583,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.70304,"AVALU":"U/L","BASE2":12.70304,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-23 20:26:34","ADY":265,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-19-id-58","SUBJID":"id-58","SITEID":"USA-19","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-19","INVNAM":"Dr. USA-19 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.54605,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 20:26:34","TRTEDTM":"2023-11-01 14:26:34","TRT01SDTM":"2020-10-31 20:26:34","TRT01EDTM":"2022-11-01 08:26:34","TRT02SDTM":"2022-11-01 08:26:34","TRT02EDTM":"2023-11-01 14:26:34","AP01SDTM":"2020-10-31 20:26:34","AP01EDTM":"2022-11-01 08:26:34","AP02SDTM":"2022-11-01 08:26:34","AP02EDTM":"2023-11-01 14:26:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-17","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4659,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":28.38175,"AVALU":"U/L","BASE2":12.70304,"BASE":28.38175,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":15.6787,"PCHG2":123.42477,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-14 20:26:34","ADY":287,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-19-id-58","SUBJID":"id-58","SITEID":"USA-19","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-19","INVNAM":"Dr. USA-19 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.54605,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 20:26:34","TRTEDTM":"2023-11-01 14:26:34","TRT01SDTM":"2020-10-31 20:26:34","TRT01EDTM":"2022-11-01 08:26:34","TRT02SDTM":"2022-11-01 08:26:34","TRT02EDTM":"2023-11-01 14:26:34","AP01SDTM":"2020-10-31 20:26:34","AP01EDTM":"2022-11-01 08:26:34","AP02SDTM":"2022-11-01 08:26:34","AP02EDTM":"2023-11-01 14:26:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-17","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":361,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":11.99279,"AVALU":"U/L","BASE2":12.70304,"BASE":28.38175,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.71025,"PCHG2":-5.59122,"CHG":-16.38896,"PCHG":-57.74471,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-15 20:26:34","ADY":288,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-19-id-58","SUBJID":"id-58","SITEID":"USA-19","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-19","INVNAM":"Dr. USA-19 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.54605,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 20:26:34","TRTEDTM":"2023-11-01 14:26:34","TRT01SDTM":"2020-10-31 20:26:34","TRT01EDTM":"2022-11-01 08:26:34","TRT02SDTM":"2022-11-01 08:26:34","TRT02EDTM":"2023-11-01 14:26:34","AP01SDTM":"2020-10-31 20:26:34","AP01EDTM":"2022-11-01 08:26:34","AP02SDTM":"2022-11-01 08:26:34","AP02EDTM":"2023-11-01 14:26:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-17","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1636,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.70585,"AVALU":"U/L","BASE2":12.70304,"BASE":28.38175,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.0028,"PCHG2":31.51059,"CHG":-11.6759,"PCHG":-41.13876,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-29 20:26:34","ADY":424,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-19-id-58","SUBJID":"id-58","SITEID":"USA-19","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-19","INVNAM":"Dr. USA-19 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.54605,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 20:26:34","TRTEDTM":"2023-11-01 14:26:34","TRT01SDTM":"2020-10-31 20:26:34","TRT01EDTM":"2022-11-01 08:26:34","TRT02SDTM":"2022-11-01 08:26:34","TRT02EDTM":"2023-11-01 14:26:34","AP01SDTM":"2020-10-31 20:26:34","AP01EDTM":"2022-11-01 08:26:34","AP02SDTM":"2022-11-01 08:26:34","AP02EDTM":"2023-11-01 14:26:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-17","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":8283,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":20.78338,"AVALU":"U/L","BASE2":12.70304,"BASE":28.38175,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.08033,"PCHG2":63.6094,"CHG":-7.59837,"PCHG":-26.77204,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-30 20:26:34","ADY":729,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-19-id-58","SUBJID":"id-58","SITEID":"USA-19","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-19","INVNAM":"Dr. USA-19 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.54605,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 20:26:34","TRTEDTM":"2023-11-01 14:26:34","TRT01SDTM":"2020-10-31 20:26:34","TRT01EDTM":"2022-11-01 08:26:34","TRT02SDTM":"2022-11-01 08:26:34","TRT02EDTM":"2023-11-01 14:26:34","AP01SDTM":"2020-10-31 20:26:34","AP01EDTM":"2022-11-01 08:26:34","AP02SDTM":"2022-11-01 08:26:34","AP02EDTM":"2023-11-01 14:26:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-17","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":841,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.09608,"AVALU":"U/L","BASE2":12.70304,"BASE":28.38175,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.39303,"PCHG2":81.81529,"CHG":-5.28567,"PCHG":-18.62348,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-30 20:26:34","ADY":972,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-19-id-58","SUBJID":"id-58","SITEID":"USA-19","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-19","INVNAM":"Dr. USA-19 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.54605,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 20:26:34","TRTEDTM":"2023-11-01 14:26:34","TRT01SDTM":"2020-10-31 20:26:34","TRT01EDTM":"2022-11-01 08:26:34","TRT02SDTM":"2022-11-01 08:26:34","TRT02EDTM":"2023-11-01 14:26:34","AP01SDTM":"2020-10-31 20:26:34","AP01EDTM":"2022-11-01 08:26:34","AP02SDTM":"2022-11-01 08:26:34","AP02EDTM":"2023-11-01 14:26:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-17","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1604,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.92099,"AVALU":"U/L","BASE2":12.70304,"BASE":28.38175,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":13.21794,"PCHG2":104.05334,"CHG":-2.46076,"PCHG":-8.67022,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-23 20:26:34","ADY":1057,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-19-id-58","SUBJID":"id-58","SITEID":"USA-19","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-19","INVNAM":"Dr. USA-19 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.54605,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 20:26:34","TRTEDTM":"2023-11-01 14:26:34","TRT01SDTM":"2020-10-31 20:26:34","TRT01EDTM":"2022-11-01 08:26:34","TRT02SDTM":"2022-11-01 08:26:34","TRT02EDTM":"2023-11-01 14:26:34","AP01SDTM":"2020-10-31 20:26:34","AP01EDTM":"2022-11-01 08:26:34","AP02SDTM":"2022-11-01 08:26:34","AP02EDTM":"2023-11-01 14:26:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-17","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4132,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.32781,"AVALU":"mg/L","BASE2":9.32781,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-23 20:26:34","ADY":265,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-19-id-58","SUBJID":"id-58","SITEID":"USA-19","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-19","INVNAM":"Dr. USA-19 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.54605,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 20:26:34","TRTEDTM":"2023-11-01 14:26:34","TRT01SDTM":"2020-10-31 20:26:34","TRT01EDTM":"2022-11-01 08:26:34","TRT02SDTM":"2022-11-01 08:26:34","TRT02EDTM":"2023-11-01 14:26:34","AP01SDTM":"2020-10-31 20:26:34","AP01EDTM":"2022-11-01 08:26:34","AP02SDTM":"2022-11-01 08:26:34","AP02EDTM":"2023-11-01 14:26:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-17","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3088,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.52869,"AVALU":"mg/L","BASE2":9.32781,"BASE":8.52869,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.79912,"PCHG2":-8.56707,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-14 20:26:34","ADY":287,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-19-id-58","SUBJID":"id-58","SITEID":"USA-19","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-19","INVNAM":"Dr. USA-19 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.54605,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 20:26:34","TRTEDTM":"2023-11-01 14:26:34","TRT01SDTM":"2020-10-31 20:26:34","TRT01EDTM":"2022-11-01 08:26:34","TRT02SDTM":"2022-11-01 08:26:34","TRT02EDTM":"2023-11-01 14:26:34","AP01SDTM":"2020-10-31 20:26:34","AP01EDTM":"2022-11-01 08:26:34","AP02SDTM":"2022-11-01 08:26:34","AP02EDTM":"2023-11-01 14:26:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-17","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1903,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.87953,"AVALU":"mg/L","BASE2":9.32781,"BASE":8.52869,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.44828,"PCHG2":-15.52644,"CHG":-0.64916,"PCHG":-7.61144,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-08-15 20:26:34","ADY":288,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-19-id-58","SUBJID":"id-58","SITEID":"USA-19","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-19","INVNAM":"Dr. USA-19 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.54605,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 20:26:34","TRTEDTM":"2023-11-01 14:26:34","TRT01SDTM":"2020-10-31 20:26:34","TRT01EDTM":"2022-11-01 08:26:34","TRT02SDTM":"2022-11-01 08:26:34","TRT02EDTM":"2023-11-01 14:26:34","AP01SDTM":"2020-10-31 20:26:34","AP01EDTM":"2022-11-01 08:26:34","AP02SDTM":"2022-11-01 08:26:34","AP02EDTM":"2023-11-01 14:26:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-17","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3874,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.52584,"AVALU":"mg/L","BASE2":9.32781,"BASE":8.52869,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.19803,"PCHG2":2.123,"CHG":0.99715,"PCHG":11.69171,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-29 20:26:34","ADY":424,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-19-id-58","SUBJID":"id-58","SITEID":"USA-19","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-19","INVNAM":"Dr. USA-19 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.54605,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 20:26:34","TRTEDTM":"2023-11-01 14:26:34","TRT01SDTM":"2020-10-31 20:26:34","TRT01EDTM":"2022-11-01 08:26:34","TRT02SDTM":"2022-11-01 08:26:34","TRT02EDTM":"2023-11-01 14:26:34","AP01SDTM":"2020-10-31 20:26:34","AP01EDTM":"2022-11-01 08:26:34","AP02SDTM":"2022-11-01 08:26:34","AP02EDTM":"2023-11-01 14:26:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-17","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4498,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.71409,"AVALU":"mg/L","BASE2":9.32781,"BASE":8.52869,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.38629,"PCHG2":4.14124,"CHG":1.18541,"PCHG":13.89906,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-30 20:26:34","ADY":729,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-19-id-58","SUBJID":"id-58","SITEID":"USA-19","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-19","INVNAM":"Dr. USA-19 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.54605,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 20:26:34","TRTEDTM":"2023-11-01 14:26:34","TRT01SDTM":"2020-10-31 20:26:34","TRT01EDTM":"2022-11-01 08:26:34","TRT02SDTM":"2022-11-01 08:26:34","TRT02EDTM":"2023-11-01 14:26:34","AP01SDTM":"2020-10-31 20:26:34","AP01EDTM":"2022-11-01 08:26:34","AP02SDTM":"2022-11-01 08:26:34","AP02EDTM":"2023-11-01 14:26:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-17","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7393,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.19047,"AVALU":"mg/L","BASE2":9.32781,"BASE":8.52869,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.13734,"PCHG2":-12.19301,"CHG":-0.33822,"PCHG":-3.96568,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-30 20:26:34","ADY":972,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-19-id-58","SUBJID":"id-58","SITEID":"USA-19","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-19","INVNAM":"Dr. USA-19 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.54605,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 20:26:34","TRTEDTM":"2023-11-01 14:26:34","TRT01SDTM":"2020-10-31 20:26:34","TRT01EDTM":"2022-11-01 08:26:34","TRT02SDTM":"2022-11-01 08:26:34","TRT02EDTM":"2023-11-01 14:26:34","AP01SDTM":"2020-10-31 20:26:34","AP01EDTM":"2022-11-01 08:26:34","AP02SDTM":"2022-11-01 08:26:34","AP02EDTM":"2023-11-01 14:26:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-17","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1191,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.86063,"AVALU":"mg/L","BASE2":9.32781,"BASE":8.52869,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.46718,"PCHG2":-15.72906,"CHG":-0.66806,"PCHG":-7.83305,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2023-09-23 20:26:34","ADY":1057,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-19-id-58","SUBJID":"id-58","SITEID":"USA-19","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-19","INVNAM":"Dr. USA-19 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.54605,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 20:26:34","TRTEDTM":"2023-11-01 14:26:34","TRT01SDTM":"2020-10-31 20:26:34","TRT01EDTM":"2022-11-01 08:26:34","TRT02SDTM":"2022-11-01 08:26:34","TRT02EDTM":"2023-11-01 14:26:34","AP01SDTM":"2020-10-31 20:26:34","AP01EDTM":"2022-11-01 08:26:34","AP02SDTM":"2022-11-01 08:26:34","AP02EDTM":"2023-11-01 14:26:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-17","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5718,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.00012,"AVALU":"g/L","BASE2":3.00012,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"2","BTOXGR":"0","ADTM":"2021-07-23 20:26:34","ADY":265,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-19-id-58","SUBJID":"id-58","SITEID":"USA-19","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-19","INVNAM":"Dr. USA-19 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.54605,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 20:26:34","TRTEDTM":"2023-11-01 14:26:34","TRT01SDTM":"2020-10-31 20:26:34","TRT01EDTM":"2022-11-01 08:26:34","TRT02SDTM":"2022-11-01 08:26:34","TRT02EDTM":"2023-11-01 14:26:34","AP01SDTM":"2020-10-31 20:26:34","AP01EDTM":"2022-11-01 08:26:34","AP02SDTM":"2022-11-01 08:26:34","AP02EDTM":"2023-11-01 14:26:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-17","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2609,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.97001,"AVALU":"g/L","BASE2":3.00012,"BASE":2.97001,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.03011,"PCHG2":-1.00357,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-14 20:26:34","ADY":287,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-19-id-58","SUBJID":"id-58","SITEID":"USA-19","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-19","INVNAM":"Dr. USA-19 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.54605,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 20:26:34","TRTEDTM":"2023-11-01 14:26:34","TRT01SDTM":"2020-10-31 20:26:34","TRT01EDTM":"2022-11-01 08:26:34","TRT02SDTM":"2022-11-01 08:26:34","TRT02EDTM":"2023-11-01 14:26:34","AP01SDTM":"2020-10-31 20:26:34","AP01EDTM":"2022-11-01 08:26:34","AP02SDTM":"2022-11-01 08:26:34","AP02EDTM":"2023-11-01 14:26:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-17","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3165,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85888,"AVALU":"g/L","BASE2":3.00012,"BASE":2.97001,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14123,"PCHG2":-4.70762,"CHG":-0.11113,"PCHG":-3.7416,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-15 20:26:34","ADY":288,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-19-id-58","SUBJID":"id-58","SITEID":"USA-19","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-19","INVNAM":"Dr. USA-19 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.54605,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 20:26:34","TRTEDTM":"2023-11-01 14:26:34","TRT01SDTM":"2020-10-31 20:26:34","TRT01EDTM":"2022-11-01 08:26:34","TRT02SDTM":"2022-11-01 08:26:34","TRT02EDTM":"2023-11-01 14:26:34","AP01SDTM":"2020-10-31 20:26:34","AP01EDTM":"2022-11-01 08:26:34","AP02SDTM":"2022-11-01 08:26:34","AP02EDTM":"2023-11-01 14:26:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-17","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4295,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96716,"AVALU":"g/L","BASE2":3.00012,"BASE":2.97001,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.03296,"PCHG2":-1.09852,"CHG":-0.00285,"PCHG":-0.09591,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-29 20:26:34","ADY":424,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-19-id-58","SUBJID":"id-58","SITEID":"USA-19","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-19","INVNAM":"Dr. USA-19 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.54605,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 20:26:34","TRTEDTM":"2023-11-01 14:26:34","TRT01SDTM":"2020-10-31 20:26:34","TRT01EDTM":"2022-11-01 08:26:34","TRT02SDTM":"2022-11-01 08:26:34","TRT02EDTM":"2023-11-01 14:26:34","AP01SDTM":"2020-10-31 20:26:34","AP01EDTM":"2022-11-01 08:26:34","AP02SDTM":"2022-11-01 08:26:34","AP02EDTM":"2023-11-01 14:26:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-17","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6570,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79489,"AVALU":"g/L","BASE2":3.00012,"BASE":2.97001,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.20523,"PCHG2":-6.84065,"CHG":-0.17512,"PCHG":-5.89625,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-10-30 20:26:34","ADY":729,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-19-id-58","SUBJID":"id-58","SITEID":"USA-19","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-19","INVNAM":"Dr. USA-19 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.54605,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 20:26:34","TRTEDTM":"2023-11-01 14:26:34","TRT01SDTM":"2020-10-31 20:26:34","TRT01EDTM":"2022-11-01 08:26:34","TRT02SDTM":"2022-11-01 08:26:34","TRT02EDTM":"2023-11-01 14:26:34","AP01SDTM":"2020-10-31 20:26:34","AP01EDTM":"2022-11-01 08:26:34","AP02SDTM":"2022-11-01 08:26:34","AP02EDTM":"2023-11-01 14:26:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-17","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5265,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96661,"AVALU":"g/L","BASE2":3.00012,"BASE":2.97001,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.0335,"PCHG2":-1.11668,"CHG":-0.00339,"PCHG":-0.11425,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-30 20:26:34","ADY":972,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-19-id-58","SUBJID":"id-58","SITEID":"USA-19","AGE":47,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-19","INVNAM":"Dr. USA-19 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":2.54605,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-10-29","TRTSDTM":"2020-10-31 20:26:34","TRTEDTM":"2023-11-01 14:26:34","TRT01SDTM":"2020-10-31 20:26:34","TRT01EDTM":"2022-11-01 08:26:34","TRT02SDTM":"2022-11-01 08:26:34","TRT02EDTM":"2023-11-01 14:26:34","AP01SDTM":"2020-10-31 20:26:34","AP01EDTM":"2022-11-01 08:26:34","AP02SDTM":"2022-11-01 08:26:34","AP02EDTM":"2023-11-01 14:26:34","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-11-01","EOSDY":1096,"LSTALVDT":"2023-11-17","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4841,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85798,"AVALU":"g/L","BASE2":3.00012,"BASE":2.97001,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14214,"PCHG2":-4.73769,"CHG":-0.11203,"PCHG":-3.77197,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-09-23 20:26:34","ADY":1057,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-2-id-110","SUBJID":"id-110","SITEID":"USA-2","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-2","INVNAM":"Dr. USA-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":9.67482,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-23","TRTSDTM":"2020-07-23 14:26:14","TRTEDTM":"2023-07-24 08:26:14","TRT01SDTM":"2020-07-23 14:26:14","TRT01EDTM":"2022-07-24 02:26:14","TRT02SDTM":"2022-07-24 02:26:14","TRT02EDTM":"2023-07-24 08:26:14","AP01SDTM":"2020-07-23 14:26:14","AP01EDTM":"2022-07-24 02:26:14","AP02SDTM":"2022-07-24 02:26:14","AP02EDTM":"2023-07-24 08:26:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-04","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2500,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.98928,"AVALU":"U/L","BASE2":7.98928,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-15 14:26:14","ADY":327,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-2-id-110","SUBJID":"id-110","SITEID":"USA-2","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-2","INVNAM":"Dr. USA-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":9.67482,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-23","TRTSDTM":"2020-07-23 14:26:14","TRTEDTM":"2023-07-24 08:26:14","TRT01SDTM":"2020-07-23 14:26:14","TRT01EDTM":"2022-07-24 02:26:14","TRT02SDTM":"2022-07-24 02:26:14","TRT02EDTM":"2023-07-24 08:26:14","AP01SDTM":"2020-07-23 14:26:14","AP01EDTM":"2022-07-24 02:26:14","AP02SDTM":"2022-07-24 02:26:14","AP02EDTM":"2023-07-24 08:26:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-04","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":111,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.39663,"AVALU":"U/L","BASE2":7.98928,"BASE":23.39663,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":15.40735,"PCHG2":192.85036,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-16 14:26:14","ADY":328,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-2-id-110","SUBJID":"id-110","SITEID":"USA-2","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-2","INVNAM":"Dr. USA-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":9.67482,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-23","TRTSDTM":"2020-07-23 14:26:14","TRTEDTM":"2023-07-24 08:26:14","TRT01SDTM":"2020-07-23 14:26:14","TRT01EDTM":"2022-07-24 02:26:14","TRT02SDTM":"2022-07-24 02:26:14","TRT02EDTM":"2023-07-24 08:26:14","AP01SDTM":"2020-07-23 14:26:14","AP01EDTM":"2022-07-24 02:26:14","AP02SDTM":"2022-07-24 02:26:14","AP02EDTM":"2023-07-24 08:26:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-04","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5298,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.17356,"AVALU":"U/L","BASE2":7.98928,"BASE":23.39663,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.18429,"PCHG2":64.89054,"CHG":-10.22307,"PCHG":-43.69461,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-27 14:26:14","ADY":369,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-2-id-110","SUBJID":"id-110","SITEID":"USA-2","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-2","INVNAM":"Dr. USA-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":9.67482,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-23","TRTSDTM":"2020-07-23 14:26:14","TRTEDTM":"2023-07-24 08:26:14","TRT01SDTM":"2020-07-23 14:26:14","TRT01EDTM":"2022-07-24 02:26:14","TRT02SDTM":"2022-07-24 02:26:14","TRT02EDTM":"2023-07-24 08:26:14","AP01SDTM":"2020-07-23 14:26:14","AP01EDTM":"2022-07-24 02:26:14","AP02SDTM":"2022-07-24 02:26:14","AP02EDTM":"2023-07-24 08:26:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-04","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5153,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.96889,"AVALU":"U/L","BASE2":7.98928,"BASE":23.39663,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.97962,"PCHG2":112.39584,"CHG":-6.42774,"PCHG":-27.47291,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-02 14:26:14","ADY":467,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-2-id-110","SUBJID":"id-110","SITEID":"USA-2","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-2","INVNAM":"Dr. USA-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":9.67482,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-23","TRTSDTM":"2020-07-23 14:26:14","TRTEDTM":"2023-07-24 08:26:14","TRT01SDTM":"2020-07-23 14:26:14","TRT01EDTM":"2022-07-24 02:26:14","TRT02SDTM":"2022-07-24 02:26:14","TRT02EDTM":"2023-07-24 08:26:14","AP01SDTM":"2020-07-23 14:26:14","AP01EDTM":"2022-07-24 02:26:14","AP02SDTM":"2022-07-24 02:26:14","AP02EDTM":"2023-07-24 08:26:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-04","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6458,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":27.36443,"AVALU":"U/L","BASE2":7.98928,"BASE":23.39663,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":19.37515,"PCHG2":242.51439,"CHG":3.9678,"PCHG":16.95884,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-16 14:26:14","ADY":754,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-2-id-110","SUBJID":"id-110","SITEID":"USA-2","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-2","INVNAM":"Dr. USA-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":9.67482,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-23","TRTSDTM":"2020-07-23 14:26:14","TRTEDTM":"2023-07-24 08:26:14","TRT01SDTM":"2020-07-23 14:26:14","TRT01EDTM":"2022-07-24 02:26:14","TRT02SDTM":"2022-07-24 02:26:14","TRT02EDTM":"2023-07-24 08:26:14","AP01SDTM":"2020-07-23 14:26:14","AP01EDTM":"2022-07-24 02:26:14","AP02SDTM":"2022-07-24 02:26:14","AP02EDTM":"2023-07-24 08:26:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-04","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4648,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":40.32362,"AVALU":"U/L","BASE2":7.98928,"BASE":23.39663,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":32.33434,"PCHG2":404.72165,"CHG":16.92699,"PCHG":72.34797,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-06 14:26:14","ADY":836,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-2-id-110","SUBJID":"id-110","SITEID":"USA-2","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-2","INVNAM":"Dr. USA-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":9.67482,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-23","TRTSDTM":"2020-07-23 14:26:14","TRTEDTM":"2023-07-24 08:26:14","TRT01SDTM":"2020-07-23 14:26:14","TRT01EDTM":"2022-07-24 02:26:14","TRT02SDTM":"2022-07-24 02:26:14","TRT02EDTM":"2023-07-24 08:26:14","AP01SDTM":"2020-07-23 14:26:14","AP01EDTM":"2022-07-24 02:26:14","AP02SDTM":"2022-07-24 02:26:14","AP02EDTM":"2023-07-24 08:26:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-04","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2873,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.26677,"AVALU":"U/L","BASE2":7.98928,"BASE":23.39663,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.27749,"PCHG2":128.64103,"CHG":-5.12986,"PCHG":-21.92564,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-17 14:26:14","ADY":998,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-2-id-110","SUBJID":"id-110","SITEID":"USA-2","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-2","INVNAM":"Dr. USA-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":9.67482,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-23","TRTSDTM":"2020-07-23 14:26:14","TRTEDTM":"2023-07-24 08:26:14","TRT01SDTM":"2020-07-23 14:26:14","TRT01EDTM":"2022-07-24 02:26:14","TRT02SDTM":"2022-07-24 02:26:14","TRT02EDTM":"2023-07-24 08:26:14","AP01SDTM":"2020-07-23 14:26:14","AP01EDTM":"2022-07-24 02:26:14","AP02SDTM":"2022-07-24 02:26:14","AP02EDTM":"2023-07-24 08:26:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-04","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3655,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.81617,"AVALU":"mg/L","BASE2":10.81617,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"1","BTOXGR":"0","ADTM":"2021-06-15 14:26:14","ADY":327,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-2-id-110","SUBJID":"id-110","SITEID":"USA-2","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-2","INVNAM":"Dr. USA-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":9.67482,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-23","TRTSDTM":"2020-07-23 14:26:14","TRTEDTM":"2023-07-24 08:26:14","TRT01SDTM":"2020-07-23 14:26:14","TRT01EDTM":"2022-07-24 02:26:14","TRT02SDTM":"2022-07-24 02:26:14","TRT02EDTM":"2023-07-24 08:26:14","AP01SDTM":"2020-07-23 14:26:14","AP01EDTM":"2022-07-24 02:26:14","AP02SDTM":"2022-07-24 02:26:14","AP02EDTM":"2023-07-24 08:26:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-04","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6007,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.69461,"AVALU":"mg/L","BASE2":10.81617,"BASE":9.69461,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-1.12156,"PCHG2":-10.36928,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-16 14:26:14","ADY":328,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-2-id-110","SUBJID":"id-110","SITEID":"USA-2","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-2","INVNAM":"Dr. USA-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":9.67482,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-23","TRTSDTM":"2020-07-23 14:26:14","TRTEDTM":"2023-07-24 08:26:14","TRT01SDTM":"2020-07-23 14:26:14","TRT01EDTM":"2022-07-24 02:26:14","TRT02SDTM":"2022-07-24 02:26:14","TRT02EDTM":"2023-07-24 08:26:14","AP01SDTM":"2020-07-23 14:26:14","AP01EDTM":"2022-07-24 02:26:14","AP02SDTM":"2022-07-24 02:26:14","AP02EDTM":"2023-07-24 08:26:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-04","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4933,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.11101,"AVALU":"mg/L","BASE2":10.81617,"BASE":9.69461,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.70516,"PCHG2":-6.51949,"CHG":0.4164,"PCHG":4.29516,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"4","BTOXGR":"0","ADTM":"2021-07-27 14:26:14","ADY":369,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-2-id-110","SUBJID":"id-110","SITEID":"USA-2","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-2","INVNAM":"Dr. USA-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":9.67482,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-23","TRTSDTM":"2020-07-23 14:26:14","TRTEDTM":"2023-07-24 08:26:14","TRT01SDTM":"2020-07-23 14:26:14","TRT01EDTM":"2022-07-24 02:26:14","TRT02SDTM":"2022-07-24 02:26:14","TRT02EDTM":"2023-07-24 08:26:14","AP01SDTM":"2020-07-23 14:26:14","AP01EDTM":"2022-07-24 02:26:14","AP02SDTM":"2022-07-24 02:26:14","AP02EDTM":"2023-07-24 08:26:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-04","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4102,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.76923,"AVALU":"mg/L","BASE2":10.81617,"BASE":9.69461,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.04694,"PCHG2":-28.17024,"CHG":-1.92538,"PCHG":-19.86034,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-11-02 14:26:14","ADY":467,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-2-id-110","SUBJID":"id-110","SITEID":"USA-2","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-2","INVNAM":"Dr. USA-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":9.67482,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-23","TRTSDTM":"2020-07-23 14:26:14","TRTEDTM":"2023-07-24 08:26:14","TRT01SDTM":"2020-07-23 14:26:14","TRT01EDTM":"2022-07-24 02:26:14","TRT02SDTM":"2022-07-24 02:26:14","TRT02EDTM":"2023-07-24 08:26:14","AP01SDTM":"2020-07-23 14:26:14","AP01EDTM":"2022-07-24 02:26:14","AP02SDTM":"2022-07-24 02:26:14","AP02EDTM":"2023-07-24 08:26:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-04","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2395,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.65728,"AVALU":"mg/L","BASE2":10.81617,"BASE":9.69461,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-3.15888,"PCHG2":-29.2052,"CHG":-2.03732,"PCHG":-21.01503,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2022-08-16 14:26:14","ADY":754,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-2-id-110","SUBJID":"id-110","SITEID":"USA-2","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-2","INVNAM":"Dr. USA-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":9.67482,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-23","TRTSDTM":"2020-07-23 14:26:14","TRTEDTM":"2023-07-24 08:26:14","TRT01SDTM":"2020-07-23 14:26:14","TRT01EDTM":"2022-07-24 02:26:14","TRT02SDTM":"2022-07-24 02:26:14","TRT02EDTM":"2023-07-24 08:26:14","AP01SDTM":"2020-07-23 14:26:14","AP01EDTM":"2022-07-24 02:26:14","AP02SDTM":"2022-07-24 02:26:14","AP02EDTM":"2023-07-24 08:26:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-04","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2468,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.1001,"AVALU":"mg/L","BASE2":10.81617,"BASE":9.69461,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.71606,"PCHG2":-15.86572,"CHG":-0.5945,"PCHG":-6.13232,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-06 14:26:14","ADY":836,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-2-id-110","SUBJID":"id-110","SITEID":"USA-2","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-2","INVNAM":"Dr. USA-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":9.67482,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-23","TRTSDTM":"2020-07-23 14:26:14","TRTEDTM":"2023-07-24 08:26:14","TRT01SDTM":"2020-07-23 14:26:14","TRT01EDTM":"2022-07-24 02:26:14","TRT02SDTM":"2022-07-24 02:26:14","TRT02EDTM":"2023-07-24 08:26:14","AP01SDTM":"2020-07-23 14:26:14","AP01EDTM":"2022-07-24 02:26:14","AP02SDTM":"2022-07-24 02:26:14","AP02EDTM":"2023-07-24 08:26:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-04","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7180,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.59511,"AVALU":"mg/L","BASE2":10.81617,"BASE":9.69461,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.22105,"PCHG2":-11.28915,"CHG":-0.09949,"PCHG":-1.02629,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-17 14:26:14","ADY":998,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-2-id-110","SUBJID":"id-110","SITEID":"USA-2","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-2","INVNAM":"Dr. USA-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":9.67482,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-23","TRTSDTM":"2020-07-23 14:26:14","TRTEDTM":"2023-07-24 08:26:14","TRT01SDTM":"2020-07-23 14:26:14","TRT01EDTM":"2022-07-24 02:26:14","TRT02SDTM":"2022-07-24 02:26:14","TRT02EDTM":"2023-07-24 08:26:14","AP01SDTM":"2020-07-23 14:26:14","AP01EDTM":"2022-07-24 02:26:14","AP02SDTM":"2022-07-24 02:26:14","AP02EDTM":"2023-07-24 08:26:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-04","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1989,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86463,"AVALU":"g/L","BASE2":2.86463,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-15 14:26:14","ADY":327,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-2-id-110","SUBJID":"id-110","SITEID":"USA-2","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-2","INVNAM":"Dr. USA-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":9.67482,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-23","TRTSDTM":"2020-07-23 14:26:14","TRTEDTM":"2023-07-24 08:26:14","TRT01SDTM":"2020-07-23 14:26:14","TRT01EDTM":"2022-07-24 02:26:14","TRT02SDTM":"2022-07-24 02:26:14","TRT02EDTM":"2023-07-24 08:26:14","AP01SDTM":"2020-07-23 14:26:14","AP01EDTM":"2022-07-24 02:26:14","AP02SDTM":"2022-07-24 02:26:14","AP02EDTM":"2023-07-24 08:26:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-04","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5776,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79245,"AVALU":"g/L","BASE2":2.86463,"BASE":2.79245,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.07219,"PCHG2":-2.5199,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-06-16 14:26:14","ADY":328,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-2-id-110","SUBJID":"id-110","SITEID":"USA-2","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-2","INVNAM":"Dr. USA-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":9.67482,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-23","TRTSDTM":"2020-07-23 14:26:14","TRTEDTM":"2023-07-24 08:26:14","TRT01SDTM":"2020-07-23 14:26:14","TRT01EDTM":"2022-07-24 02:26:14","TRT02SDTM":"2022-07-24 02:26:14","TRT02EDTM":"2023-07-24 08:26:14","AP01SDTM":"2020-07-23 14:26:14","AP01EDTM":"2022-07-24 02:26:14","AP02SDTM":"2022-07-24 02:26:14","AP02EDTM":"2023-07-24 08:26:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-04","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3939,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88192,"AVALU":"g/L","BASE2":2.86463,"BASE":2.79245,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01728,"PCHG2":0.60332,"CHG":0.08947,"PCHG":3.20396,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-27 14:26:14","ADY":369,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-2-id-110","SUBJID":"id-110","SITEID":"USA-2","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-2","INVNAM":"Dr. USA-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":9.67482,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-23","TRTSDTM":"2020-07-23 14:26:14","TRTEDTM":"2023-07-24 08:26:14","TRT01SDTM":"2020-07-23 14:26:14","TRT01EDTM":"2022-07-24 02:26:14","TRT02SDTM":"2022-07-24 02:26:14","TRT02EDTM":"2023-07-24 08:26:14","AP01SDTM":"2020-07-23 14:26:14","AP01EDTM":"2022-07-24 02:26:14","AP02SDTM":"2022-07-24 02:26:14","AP02EDTM":"2023-07-24 08:26:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-04","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3657,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84907,"AVALU":"g/L","BASE2":2.86463,"BASE":2.79245,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01557,"PCHG2":-0.54347,"CHG":0.05662,"PCHG":2.02753,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-02 14:26:14","ADY":467,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-2-id-110","SUBJID":"id-110","SITEID":"USA-2","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-2","INVNAM":"Dr. USA-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":9.67482,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-23","TRTSDTM":"2020-07-23 14:26:14","TRTEDTM":"2023-07-24 08:26:14","TRT01SDTM":"2020-07-23 14:26:14","TRT01EDTM":"2022-07-24 02:26:14","TRT02SDTM":"2022-07-24 02:26:14","TRT02EDTM":"2023-07-24 08:26:14","AP01SDTM":"2020-07-23 14:26:14","AP01EDTM":"2022-07-24 02:26:14","AP02SDTM":"2022-07-24 02:26:14","AP02EDTM":"2023-07-24 08:26:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-04","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3950,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85094,"AVALU":"g/L","BASE2":2.86463,"BASE":2.79245,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01369,"PCHG2":-0.478,"CHG":0.05849,"PCHG":2.09468,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-08-16 14:26:14","ADY":754,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-2-id-110","SUBJID":"id-110","SITEID":"USA-2","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-2","INVNAM":"Dr. USA-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":9.67482,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-23","TRTSDTM":"2020-07-23 14:26:14","TRTEDTM":"2023-07-24 08:26:14","TRT01SDTM":"2020-07-23 14:26:14","TRT01EDTM":"2022-07-24 02:26:14","TRT02SDTM":"2022-07-24 02:26:14","TRT02EDTM":"2023-07-24 08:26:14","AP01SDTM":"2020-07-23 14:26:14","AP01EDTM":"2022-07-24 02:26:14","AP02SDTM":"2022-07-24 02:26:14","AP02EDTM":"2023-07-24 08:26:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-04","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2888,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9034,"AVALU":"g/L","BASE2":2.86463,"BASE":2.79245,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03877,"PCHG2":1.35337,"CHG":0.11095,"PCHG":3.97339,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-06 14:26:14","ADY":836,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-2-id-110","SUBJID":"id-110","SITEID":"USA-2","AGE":35,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-2","INVNAM":"Dr. USA-2 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S2","BMRKR1":9.67482,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-23","TRTSDTM":"2020-07-23 14:26:14","TRTEDTM":"2023-07-24 08:26:14","TRT01SDTM":"2020-07-23 14:26:14","TRT01EDTM":"2022-07-24 02:26:14","TRT02SDTM":"2022-07-24 02:26:14","TRT02EDTM":"2023-07-24 08:26:14","AP01SDTM":"2020-07-23 14:26:14","AP01EDTM":"2022-07-24 02:26:14","AP02SDTM":"2022-07-24 02:26:14","AP02EDTM":"2023-07-24 08:26:14","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-24","EOSDY":1096,"LSTALVDT":"2023-08-04","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7963,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94585,"AVALU":"g/L","BASE2":2.86463,"BASE":2.79245,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08122,"PCHG2":2.83525,"CHG":0.15341,"PCHG":5.49358,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-17 14:26:14","ADY":998,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-282","SUBJID":"id-282","SITEID":"USA-3","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.35944,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-20 03:57:30","TRTEDTM":"2023-07-20 21:57:30","TRT01SDTM":"2020-07-20 03:57:30","TRT01EDTM":"2022-07-20 15:57:30","TRT02SDTM":"2022-07-20 15:57:30","TRT02EDTM":"2023-07-20 21:57:30","AP01SDTM":"2020-07-20 03:57:30","AP01EDTM":"2022-07-20 15:57:30","AP02SDTM":"2022-07-20 15:57:30","AP02EDTM":"2023-07-20 21:57:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6858,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.98768,"AVALU":"U/L","BASE2":10.98768,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-20 03:57:30","ADY":184,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-282","SUBJID":"id-282","SITEID":"USA-3","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.35944,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-20 03:57:30","TRTEDTM":"2023-07-20 21:57:30","TRT01SDTM":"2020-07-20 03:57:30","TRT01EDTM":"2022-07-20 15:57:30","TRT02SDTM":"2022-07-20 15:57:30","TRT02EDTM":"2023-07-20 21:57:30","AP01SDTM":"2020-07-20 03:57:30","AP01EDTM":"2022-07-20 15:57:30","AP02SDTM":"2022-07-20 15:57:30","AP02EDTM":"2023-07-20 21:57:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":165,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.82233,"AVALU":"U/L","BASE2":10.98768,"BASE":18.82233,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":7.83465,"PCHG2":71.3039,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-30 03:57:30","ADY":194,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-282","SUBJID":"id-282","SITEID":"USA-3","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.35944,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-20 03:57:30","TRTEDTM":"2023-07-20 21:57:30","TRT01SDTM":"2020-07-20 03:57:30","TRT01EDTM":"2022-07-20 15:57:30","TRT02SDTM":"2022-07-20 15:57:30","TRT02EDTM":"2023-07-20 21:57:30","AP01SDTM":"2020-07-20 03:57:30","AP01EDTM":"2022-07-20 15:57:30","AP02SDTM":"2022-07-20 15:57:30","AP02EDTM":"2023-07-20 21:57:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2791,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.11406,"AVALU":"U/L","BASE2":10.98768,"BASE":18.82233,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":12.12637,"PCHG2":110.36334,"CHG":4.29173,"PCHG":22.80126,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-07 03:57:30","ADY":383,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-282","SUBJID":"id-282","SITEID":"USA-3","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.35944,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-20 03:57:30","TRTEDTM":"2023-07-20 21:57:30","TRT01SDTM":"2020-07-20 03:57:30","TRT01EDTM":"2022-07-20 15:57:30","TRT02SDTM":"2022-07-20 15:57:30","TRT02EDTM":"2023-07-20 21:57:30","AP01SDTM":"2020-07-20 03:57:30","AP01EDTM":"2022-07-20 15:57:30","AP02SDTM":"2022-07-20 15:57:30","AP02EDTM":"2023-07-20 21:57:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5212,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.41644,"AVALU":"U/L","BASE2":10.98768,"BASE":18.82233,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":4.42876,"PCHG2":40.30658,"CHG":-3.40589,"PCHG":-18.09493,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-10 03:57:30","ADY":478,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-282","SUBJID":"id-282","SITEID":"USA-3","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.35944,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-20 03:57:30","TRTEDTM":"2023-07-20 21:57:30","TRT01SDTM":"2020-07-20 03:57:30","TRT01EDTM":"2022-07-20 15:57:30","TRT02SDTM":"2022-07-20 15:57:30","TRT02EDTM":"2023-07-20 21:57:30","AP01SDTM":"2020-07-20 03:57:30","AP01EDTM":"2022-07-20 15:57:30","AP02SDTM":"2022-07-20 15:57:30","AP02EDTM":"2023-07-20 21:57:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2356,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.33176,"AVALU":"U/L","BASE2":10.98768,"BASE":18.82233,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":7.34408,"PCHG2":66.83918,"CHG":-0.49057,"PCHG":-2.60631,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-15 03:57:30","ADY":909,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-282","SUBJID":"id-282","SITEID":"USA-3","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.35944,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-20 03:57:30","TRTEDTM":"2023-07-20 21:57:30","TRT01SDTM":"2020-07-20 03:57:30","TRT01EDTM":"2022-07-20 15:57:30","TRT02SDTM":"2022-07-20 15:57:30","TRT02EDTM":"2023-07-20 21:57:30","AP01SDTM":"2020-07-20 03:57:30","AP01EDTM":"2022-07-20 15:57:30","AP02SDTM":"2022-07-20 15:57:30","AP02EDTM":"2023-07-20 21:57:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2698,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":8.32997,"AVALU":"U/L","BASE2":10.98768,"BASE":18.82233,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.65771,"PCHG2":-24.18808,"CHG":-10.49236,"PCHG":-55.74419,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-04 03:57:30","ADY":988,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-282","SUBJID":"id-282","SITEID":"USA-3","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.35944,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-20 03:57:30","TRTEDTM":"2023-07-20 21:57:30","TRT01SDTM":"2020-07-20 03:57:30","TRT01EDTM":"2022-07-20 15:57:30","TRT02SDTM":"2022-07-20 15:57:30","TRT02EDTM":"2023-07-20 21:57:30","AP01SDTM":"2020-07-20 03:57:30","AP01EDTM":"2022-07-20 15:57:30","AP02SDTM":"2022-07-20 15:57:30","AP02EDTM":"2023-07-20 21:57:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3647,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.73245,"AVALU":"U/L","BASE2":10.98768,"BASE":18.82233,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.74477,"PCHG2":79.587,"CHG":0.91012,"PCHG":4.83533,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-23 03:57:30","ADY":1068,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-282","SUBJID":"id-282","SITEID":"USA-3","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.35944,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-20 03:57:30","TRTEDTM":"2023-07-20 21:57:30","TRT01SDTM":"2020-07-20 03:57:30","TRT01EDTM":"2022-07-20 15:57:30","TRT02SDTM":"2022-07-20 15:57:30","TRT02EDTM":"2023-07-20 21:57:30","AP01SDTM":"2020-07-20 03:57:30","AP01EDTM":"2022-07-20 15:57:30","AP02SDTM":"2022-07-20 15:57:30","AP02EDTM":"2023-07-20 21:57:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8005,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.54326,"AVALU":"mg/L","BASE2":10.54326,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"","ATOXGR":"3","BTOXGR":"-1","ADTM":"2021-01-20 03:57:30","ADY":184,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-282","SUBJID":"id-282","SITEID":"USA-3","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.35944,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-20 03:57:30","TRTEDTM":"2023-07-20 21:57:30","TRT01SDTM":"2020-07-20 03:57:30","TRT01EDTM":"2022-07-20 15:57:30","TRT02SDTM":"2022-07-20 15:57:30","TRT02EDTM":"2023-07-20 21:57:30","AP01SDTM":"2020-07-20 03:57:30","AP01EDTM":"2022-07-20 15:57:30","AP02SDTM":"2022-07-20 15:57:30","AP02EDTM":"2023-07-20 21:57:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7872,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.64705,"AVALU":"mg/L","BASE2":10.54326,"BASE":7.64705,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-2.89621,"PCHG2":-27.46977,"CHG":0,"PCHG":0,"ANRIND":"LOW","BNRIND":"LOW","SHIFT1":"","ATOXGR":"-1","BTOXGR":"-1","ADTM":"2021-01-30 03:57:30","ADY":194,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-282","SUBJID":"id-282","SITEID":"USA-3","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.35944,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-20 03:57:30","TRTEDTM":"2023-07-20 21:57:30","TRT01SDTM":"2020-07-20 03:57:30","TRT01EDTM":"2022-07-20 15:57:30","TRT02SDTM":"2022-07-20 15:57:30","TRT02EDTM":"2023-07-20 21:57:30","AP01SDTM":"2020-07-20 03:57:30","AP01EDTM":"2022-07-20 15:57:30","AP02SDTM":"2022-07-20 15:57:30","AP02EDTM":"2023-07-20 21:57:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3379,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.25038,"AVALU":"mg/L","BASE2":10.54326,"BASE":7.64705,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.29288,"PCHG2":-2.77789,"CHG":2.60333,"PCHG":34.04357,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"2","BTOXGR":"-1","ADTM":"2021-08-07 03:57:30","ADY":383,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-282","SUBJID":"id-282","SITEID":"USA-3","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.35944,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-20 03:57:30","TRTEDTM":"2023-07-20 21:57:30","TRT01SDTM":"2020-07-20 03:57:30","TRT01EDTM":"2022-07-20 15:57:30","TRT02SDTM":"2022-07-20 15:57:30","TRT02EDTM":"2023-07-20 21:57:30","AP01SDTM":"2020-07-20 03:57:30","AP01EDTM":"2022-07-20 15:57:30","AP02SDTM":"2022-07-20 15:57:30","AP02EDTM":"2023-07-20 21:57:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2042,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.33252,"AVALU":"mg/L","BASE2":10.54326,"BASE":7.64705,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21074,"PCHG2":-1.99883,"CHG":2.68547,"PCHG":35.11769,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"3","BTOXGR":"-1","ADTM":"2021-11-10 03:57:30","ADY":478,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-282","SUBJID":"id-282","SITEID":"USA-3","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.35944,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-20 03:57:30","TRTEDTM":"2023-07-20 21:57:30","TRT01SDTM":"2020-07-20 03:57:30","TRT01EDTM":"2022-07-20 15:57:30","TRT02SDTM":"2022-07-20 15:57:30","TRT02EDTM":"2023-07-20 21:57:30","AP01SDTM":"2020-07-20 03:57:30","AP01EDTM":"2022-07-20 15:57:30","AP02SDTM":"2022-07-20 15:57:30","AP02EDTM":"2023-07-20 21:57:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1284,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.19612,"AVALU":"mg/L","BASE2":10.54326,"BASE":7.64705,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.34715,"PCHG2":-3.29259,"CHG":2.54906,"PCHG":33.33394,"ANRIND":"HIGH","BNRIND":"LOW","SHIFT1":"LOW to HIGH","ATOXGR":"1","BTOXGR":"-1","ADTM":"2023-01-15 03:57:30","ADY":909,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-282","SUBJID":"id-282","SITEID":"USA-3","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.35944,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-20 03:57:30","TRTEDTM":"2023-07-20 21:57:30","TRT01SDTM":"2020-07-20 03:57:30","TRT01EDTM":"2022-07-20 15:57:30","TRT02SDTM":"2022-07-20 15:57:30","TRT02EDTM":"2023-07-20 21:57:30","AP01SDTM":"2020-07-20 03:57:30","AP01EDTM":"2022-07-20 15:57:30","AP02SDTM":"2022-07-20 15:57:30","AP02EDTM":"2023-07-20 21:57:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5202,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.39784,"AVALU":"mg/L","BASE2":10.54326,"BASE":7.64705,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.14542,"PCHG2":-20.3487,"CHG":0.75079,"PCHG":9.81807,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2023-04-04 03:57:30","ADY":988,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-282","SUBJID":"id-282","SITEID":"USA-3","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.35944,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-20 03:57:30","TRTEDTM":"2023-07-20 21:57:30","TRT01SDTM":"2020-07-20 03:57:30","TRT01EDTM":"2022-07-20 15:57:30","TRT02SDTM":"2022-07-20 15:57:30","TRT02EDTM":"2023-07-20 21:57:30","AP01SDTM":"2020-07-20 03:57:30","AP01EDTM":"2022-07-20 15:57:30","AP02SDTM":"2022-07-20 15:57:30","AP02EDTM":"2023-07-20 21:57:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1948,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.37859,"AVALU":"mg/L","BASE2":10.54326,"BASE":7.64705,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.16467,"PCHG2":-20.53131,"CHG":0.73154,"PCHG":9.56631,"ANRIND":"NORMAL","BNRIND":"LOW","SHIFT1":"LOW to NORMAL","ATOXGR":"0","BTOXGR":"-1","ADTM":"2023-06-23 03:57:30","ADY":1068,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"1","BTOXGRH":"","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-282","SUBJID":"id-282","SITEID":"USA-3","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.35944,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-20 03:57:30","TRTEDTM":"2023-07-20 21:57:30","TRT01SDTM":"2020-07-20 03:57:30","TRT01EDTM":"2022-07-20 15:57:30","TRT02SDTM":"2022-07-20 15:57:30","TRT02EDTM":"2023-07-20 21:57:30","AP01SDTM":"2020-07-20 03:57:30","AP01EDTM":"2022-07-20 15:57:30","AP02SDTM":"2022-07-20 15:57:30","AP02EDTM":"2023-07-20 21:57:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7169,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92651,"AVALU":"g/L","BASE2":2.92651,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-20 03:57:30","ADY":184,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-282","SUBJID":"id-282","SITEID":"USA-3","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.35944,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-20 03:57:30","TRTEDTM":"2023-07-20 21:57:30","TRT01SDTM":"2020-07-20 03:57:30","TRT01EDTM":"2022-07-20 15:57:30","TRT02SDTM":"2022-07-20 15:57:30","TRT02EDTM":"2023-07-20 21:57:30","AP01SDTM":"2020-07-20 03:57:30","AP01EDTM":"2022-07-20 15:57:30","AP02SDTM":"2022-07-20 15:57:30","AP02EDTM":"2023-07-20 21:57:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":318,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81327,"AVALU":"g/L","BASE2":2.92651,"BASE":2.81327,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.11324,"PCHG2":-3.8695,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-30 03:57:30","ADY":194,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-282","SUBJID":"id-282","SITEID":"USA-3","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.35944,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-20 03:57:30","TRTEDTM":"2023-07-20 21:57:30","TRT01SDTM":"2020-07-20 03:57:30","TRT01EDTM":"2022-07-20 15:57:30","TRT02SDTM":"2022-07-20 15:57:30","TRT02EDTM":"2023-07-20 21:57:30","AP01SDTM":"2020-07-20 03:57:30","AP01EDTM":"2022-07-20 15:57:30","AP02SDTM":"2022-07-20 15:57:30","AP02EDTM":"2023-07-20 21:57:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7863,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98684,"AVALU":"g/L","BASE2":2.92651,"BASE":2.81327,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06034,"PCHG2":2.06174,"CHG":0.17358,"PCHG":6.16999,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-08-07 03:57:30","ADY":383,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-282","SUBJID":"id-282","SITEID":"USA-3","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.35944,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-20 03:57:30","TRTEDTM":"2023-07-20 21:57:30","TRT01SDTM":"2020-07-20 03:57:30","TRT01EDTM":"2022-07-20 15:57:30","TRT02SDTM":"2022-07-20 15:57:30","TRT02EDTM":"2023-07-20 21:57:30","AP01SDTM":"2020-07-20 03:57:30","AP01EDTM":"2022-07-20 15:57:30","AP02SDTM":"2022-07-20 15:57:30","AP02EDTM":"2023-07-20 21:57:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1007,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85387,"AVALU":"g/L","BASE2":2.92651,"BASE":2.81327,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.07263,"PCHG2":-2.48188,"CHG":0.04061,"PCHG":1.44347,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-11-10 03:57:30","ADY":478,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-282","SUBJID":"id-282","SITEID":"USA-3","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.35944,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-20 03:57:30","TRTEDTM":"2023-07-20 21:57:30","TRT01SDTM":"2020-07-20 03:57:30","TRT01EDTM":"2022-07-20 15:57:30","TRT02SDTM":"2022-07-20 15:57:30","TRT02EDTM":"2023-07-20 21:57:30","AP01SDTM":"2020-07-20 03:57:30","AP01EDTM":"2022-07-20 15:57:30","AP02SDTM":"2022-07-20 15:57:30","AP02EDTM":"2023-07-20 21:57:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7322,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90036,"AVALU":"g/L","BASE2":2.92651,"BASE":2.81327,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.02615,"PCHG2":-0.89358,"CHG":0.08709,"PCHG":3.09571,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-01-15 03:57:30","ADY":909,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-282","SUBJID":"id-282","SITEID":"USA-3","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.35944,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-20 03:57:30","TRTEDTM":"2023-07-20 21:57:30","TRT01SDTM":"2020-07-20 03:57:30","TRT01EDTM":"2022-07-20 15:57:30","TRT02SDTM":"2022-07-20 15:57:30","TRT02EDTM":"2023-07-20 21:57:30","AP01SDTM":"2020-07-20 03:57:30","AP01EDTM":"2022-07-20 15:57:30","AP02SDTM":"2022-07-20 15:57:30","AP02EDTM":"2023-07-20 21:57:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5205,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.98988,"AVALU":"g/L","BASE2":2.92651,"BASE":2.81327,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06338,"PCHG2":2.16558,"CHG":0.17662,"PCHG":6.278,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-04-04 03:57:30","ADY":988,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-282","SUBJID":"id-282","SITEID":"USA-3","AGE":38,"AGEU":"YEARS","SEX":"M","RACE":"AMERICAN INDIAN OR ALASKA NATIVE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"A: Drug X","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":3.35944,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2020-07-19","TRTSDTM":"2020-07-20 03:57:30","TRTEDTM":"2023-07-20 21:57:30","TRT01SDTM":"2020-07-20 03:57:30","TRT01EDTM":"2022-07-20 15:57:30","TRT02SDTM":"2022-07-20 15:57:30","TRT02EDTM":"2023-07-20 21:57:30","AP01SDTM":"2020-07-20 03:57:30","AP01EDTM":"2022-07-20 15:57:30","AP02SDTM":"2022-07-20 15:57:30","AP02EDTM":"2023-07-20 21:57:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-20","EOSDY":1096,"LSTALVDT":"2023-08-13","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4411,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.90958,"AVALU":"g/L","BASE2":2.92651,"BASE":2.81327,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01692,"PCHG2":-0.57828,"CHG":0.09632,"PCHG":3.4237,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2023-06-23 03:57:30","ADY":1068,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-320","SUBJID":"id-320","SITEID":"USA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.73445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 11:44:23","TRTEDTM":"2022-07-29 05:44:23","TRT01SDTM":"2019-07-29 11:44:23","TRT01EDTM":"2021-07-28 23:44:23","TRT02SDTM":"2021-07-28 23:44:23","TRT02EDTM":"2022-07-29 05:44:23","AP01SDTM":"2019-07-29 11:44:23","AP01EDTM":"2021-07-28 23:44:23","AP02SDTM":"2021-07-28 23:44:23","AP02EDTM":"2022-07-29 05:44:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-26","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":227,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.56708,"AVALU":"U/L","BASE2":13.56708,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-01 11:44:23","ADY":125,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-320","SUBJID":"id-320","SITEID":"USA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.73445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 11:44:23","TRTEDTM":"2022-07-29 05:44:23","TRT01SDTM":"2019-07-29 11:44:23","TRT01EDTM":"2021-07-28 23:44:23","TRT02SDTM":"2021-07-28 23:44:23","TRT02EDTM":"2022-07-29 05:44:23","AP01SDTM":"2019-07-29 11:44:23","AP01EDTM":"2021-07-28 23:44:23","AP02SDTM":"2021-07-28 23:44:23","AP02EDTM":"2022-07-29 05:44:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-26","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1595,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.07023,"AVALU":"U/L","BASE2":13.56708,"BASE":21.07023,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":7.50315,"PCHG2":55.30408,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-28 11:44:23","ADY":335,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-320","SUBJID":"id-320","SITEID":"USA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.73445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 11:44:23","TRTEDTM":"2022-07-29 05:44:23","TRT01SDTM":"2019-07-29 11:44:23","TRT01EDTM":"2021-07-28 23:44:23","TRT02SDTM":"2021-07-28 23:44:23","TRT02EDTM":"2022-07-29 05:44:23","AP01SDTM":"2019-07-29 11:44:23","AP01EDTM":"2021-07-28 23:44:23","AP02SDTM":"2021-07-28 23:44:23","AP02EDTM":"2022-07-29 05:44:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-26","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5773,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.25395,"AVALU":"U/L","BASE2":13.56708,"BASE":21.07023,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.68687,"PCHG2":41.91665,"CHG":-1.81628,"PCHG":-8.62014,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-10 11:44:23","ADY":651,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-320","SUBJID":"id-320","SITEID":"USA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.73445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 11:44:23","TRTEDTM":"2022-07-29 05:44:23","TRT01SDTM":"2019-07-29 11:44:23","TRT01EDTM":"2021-07-28 23:44:23","TRT02SDTM":"2021-07-28 23:44:23","TRT02EDTM":"2022-07-29 05:44:23","AP01SDTM":"2019-07-29 11:44:23","AP01EDTM":"2021-07-28 23:44:23","AP02SDTM":"2021-07-28 23:44:23","AP02EDTM":"2022-07-29 05:44:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-26","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6847,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.13379,"AVALU":"U/L","BASE2":13.56708,"BASE":21.07023,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":11.56671,"PCHG2":85.25571,"CHG":4.06356,"PCHG":19.2858,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-23 11:44:23","ADY":878,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-320","SUBJID":"id-320","SITEID":"USA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.73445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 11:44:23","TRTEDTM":"2022-07-29 05:44:23","TRT01SDTM":"2019-07-29 11:44:23","TRT01EDTM":"2021-07-28 23:44:23","TRT02SDTM":"2021-07-28 23:44:23","TRT02EDTM":"2022-07-29 05:44:23","AP01SDTM":"2019-07-29 11:44:23","AP01EDTM":"2021-07-28 23:44:23","AP02SDTM":"2021-07-28 23:44:23","AP02EDTM":"2022-07-29 05:44:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-26","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":634,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.50645,"AVALU":"U/L","BASE2":13.56708,"BASE":21.07023,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":10.93937,"PCHG2":80.63169,"CHG":3.43622,"PCHG":16.3084,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-27 11:44:23","ADY":882,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-320","SUBJID":"id-320","SITEID":"USA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.73445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 11:44:23","TRTEDTM":"2022-07-29 05:44:23","TRT01SDTM":"2019-07-29 11:44:23","TRT01EDTM":"2021-07-28 23:44:23","TRT02SDTM":"2021-07-28 23:44:23","TRT02EDTM":"2022-07-29 05:44:23","AP01SDTM":"2019-07-29 11:44:23","AP01EDTM":"2021-07-28 23:44:23","AP02SDTM":"2021-07-28 23:44:23","AP02EDTM":"2022-07-29 05:44:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-26","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6653,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.50601,"AVALU":"U/L","BASE2":13.56708,"BASE":21.07023,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.06107,"PCHG2":-0.45016,"CHG":-7.56422,"PCHG":-35.90004,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-24 11:44:23","ADY":969,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-320","SUBJID":"id-320","SITEID":"USA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.73445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 11:44:23","TRTEDTM":"2022-07-29 05:44:23","TRT01SDTM":"2019-07-29 11:44:23","TRT01EDTM":"2021-07-28 23:44:23","TRT02SDTM":"2021-07-28 23:44:23","TRT02EDTM":"2022-07-29 05:44:23","AP01SDTM":"2019-07-29 11:44:23","AP01EDTM":"2021-07-28 23:44:23","AP02SDTM":"2021-07-28 23:44:23","AP02EDTM":"2022-07-29 05:44:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-26","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":35,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.62775,"AVALU":"U/L","BASE2":13.56708,"BASE":21.07023,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.06066,"PCHG2":0.44714,"CHG":-7.44248,"PCHG":-35.32228,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-22 11:44:23","ADY":1028,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-320","SUBJID":"id-320","SITEID":"USA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.73445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 11:44:23","TRTEDTM":"2022-07-29 05:44:23","TRT01SDTM":"2019-07-29 11:44:23","TRT01EDTM":"2021-07-28 23:44:23","TRT02SDTM":"2021-07-28 23:44:23","TRT02EDTM":"2022-07-29 05:44:23","AP01SDTM":"2019-07-29 11:44:23","AP01EDTM":"2021-07-28 23:44:23","AP02SDTM":"2021-07-28 23:44:23","AP02EDTM":"2022-07-29 05:44:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-26","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5623,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.78824,"AVALU":"mg/L","BASE2":7.78824,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"-4","BTOXGR":"2","ADTM":"2019-12-01 11:44:23","ADY":125,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-320","SUBJID":"id-320","SITEID":"USA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.73445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 11:44:23","TRTEDTM":"2022-07-29 05:44:23","TRT01SDTM":"2019-07-29 11:44:23","TRT01EDTM":"2021-07-28 23:44:23","TRT02SDTM":"2021-07-28 23:44:23","TRT02EDTM":"2022-07-29 05:44:23","AP01SDTM":"2019-07-29 11:44:23","AP01EDTM":"2021-07-28 23:44:23","AP02SDTM":"2021-07-28 23:44:23","AP02EDTM":"2022-07-29 05:44:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-26","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7058,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.9331,"AVALU":"mg/L","BASE2":7.78824,"BASE":10.9331,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":3.14486,"PCHG2":40.37958,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"2","BTOXGR":"2","ADTM":"2020-06-28 11:44:23","ADY":335,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-320","SUBJID":"id-320","SITEID":"USA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.73445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 11:44:23","TRTEDTM":"2022-07-29 05:44:23","TRT01SDTM":"2019-07-29 11:44:23","TRT01EDTM":"2021-07-28 23:44:23","TRT02SDTM":"2021-07-28 23:44:23","TRT02EDTM":"2022-07-29 05:44:23","AP01SDTM":"2019-07-29 11:44:23","AP01EDTM":"2021-07-28 23:44:23","AP02SDTM":"2021-07-28 23:44:23","AP02EDTM":"2022-07-29 05:44:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-26","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1706,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.25123,"AVALU":"mg/L","BASE2":7.78824,"BASE":10.9331,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.46299,"PCHG2":18.7846,"CHG":-1.68187,"PCHG":-15.38328,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-05-10 11:44:23","ADY":651,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-320","SUBJID":"id-320","SITEID":"USA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.73445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 11:44:23","TRTEDTM":"2022-07-29 05:44:23","TRT01SDTM":"2019-07-29 11:44:23","TRT01EDTM":"2021-07-28 23:44:23","TRT02SDTM":"2021-07-28 23:44:23","TRT02EDTM":"2022-07-29 05:44:23","AP01SDTM":"2019-07-29 11:44:23","AP01EDTM":"2021-07-28 23:44:23","AP02SDTM":"2021-07-28 23:44:23","AP02EDTM":"2022-07-29 05:44:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-26","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3697,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.36745,"AVALU":"mg/L","BASE2":7.78824,"BASE":10.9331,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.57921,"PCHG2":20.27685,"CHG":-1.56565,"PCHG":-14.32026,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-12-23 11:44:23","ADY":878,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-320","SUBJID":"id-320","SITEID":"USA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.73445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 11:44:23","TRTEDTM":"2022-07-29 05:44:23","TRT01SDTM":"2019-07-29 11:44:23","TRT01EDTM":"2021-07-28 23:44:23","TRT02SDTM":"2021-07-28 23:44:23","TRT02EDTM":"2022-07-29 05:44:23","AP01SDTM":"2019-07-29 11:44:23","AP01EDTM":"2021-07-28 23:44:23","AP02SDTM":"2021-07-28 23:44:23","AP02EDTM":"2022-07-29 05:44:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-26","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":895,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.95457,"AVALU":"mg/L","BASE2":7.78824,"BASE":10.9331,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.16633,"PCHG2":14.97546,"CHG":-1.97853,"PCHG":-18.09673,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2021-12-27 11:44:23","ADY":882,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-320","SUBJID":"id-320","SITEID":"USA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.73445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 11:44:23","TRTEDTM":"2022-07-29 05:44:23","TRT01SDTM":"2019-07-29 11:44:23","TRT01EDTM":"2021-07-28 23:44:23","TRT02SDTM":"2021-07-28 23:44:23","TRT02EDTM":"2022-07-29 05:44:23","AP01SDTM":"2019-07-29 11:44:23","AP01EDTM":"2021-07-28 23:44:23","AP02SDTM":"2021-07-28 23:44:23","AP02EDTM":"2022-07-29 05:44:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-26","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6119,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.41013,"AVALU":"mg/L","BASE2":7.78824,"BASE":10.9331,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.62188,"PCHG2":20.82478,"CHG":-1.52298,"PCHG":-13.92995,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"2","ADTM":"2022-03-24 11:44:23","ADY":969,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-320","SUBJID":"id-320","SITEID":"USA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.73445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 11:44:23","TRTEDTM":"2022-07-29 05:44:23","TRT01SDTM":"2019-07-29 11:44:23","TRT01EDTM":"2021-07-28 23:44:23","TRT02SDTM":"2021-07-28 23:44:23","TRT02EDTM":"2022-07-29 05:44:23","AP01SDTM":"2019-07-29 11:44:23","AP01EDTM":"2021-07-28 23:44:23","AP02SDTM":"2021-07-28 23:44:23","AP02EDTM":"2022-07-29 05:44:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-26","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5312,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.03291,"AVALU":"mg/L","BASE2":7.78824,"BASE":10.9331,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.24467,"PCHG2":28.82124,"CHG":-0.90019,"PCHG":-8.23363,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"1","BTOXGR":"2","ADTM":"2022-05-22 11:44:23","ADY":1028,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"2","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-320","SUBJID":"id-320","SITEID":"USA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.73445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 11:44:23","TRTEDTM":"2022-07-29 05:44:23","TRT01SDTM":"2019-07-29 11:44:23","TRT01EDTM":"2021-07-28 23:44:23","TRT02SDTM":"2021-07-28 23:44:23","TRT02EDTM":"2022-07-29 05:44:23","AP01SDTM":"2019-07-29 11:44:23","AP01EDTM":"2021-07-28 23:44:23","AP02SDTM":"2021-07-28 23:44:23","AP02EDTM":"2022-07-29 05:44:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-26","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4415,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.05702,"AVALU":"g/L","BASE2":3.05702,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"3","BTOXGR":"0","ADTM":"2019-12-01 11:44:23","ADY":125,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-320","SUBJID":"id-320","SITEID":"USA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.73445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 11:44:23","TRTEDTM":"2022-07-29 05:44:23","TRT01SDTM":"2019-07-29 11:44:23","TRT01EDTM":"2021-07-28 23:44:23","TRT02SDTM":"2021-07-28 23:44:23","TRT02EDTM":"2022-07-29 05:44:23","AP01SDTM":"2019-07-29 11:44:23","AP01EDTM":"2021-07-28 23:44:23","AP02SDTM":"2021-07-28 23:44:23","AP02EDTM":"2022-07-29 05:44:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-26","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3176,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9765,"AVALU":"g/L","BASE2":3.05702,"BASE":2.9765,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.08052,"PCHG2":-2.63399,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-06-28 11:44:23","ADY":335,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-320","SUBJID":"id-320","SITEID":"USA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.73445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 11:44:23","TRTEDTM":"2022-07-29 05:44:23","TRT01SDTM":"2019-07-29 11:44:23","TRT01EDTM":"2021-07-28 23:44:23","TRT02SDTM":"2021-07-28 23:44:23","TRT02EDTM":"2022-07-29 05:44:23","AP01SDTM":"2019-07-29 11:44:23","AP01EDTM":"2021-07-28 23:44:23","AP02SDTM":"2021-07-28 23:44:23","AP02EDTM":"2022-07-29 05:44:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-26","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1938,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9751,"AVALU":"g/L","BASE2":3.05702,"BASE":2.9765,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08193,"PCHG2":-2.67997,"CHG":-0.00141,"PCHG":-0.04723,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-10 11:44:23","ADY":651,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-320","SUBJID":"id-320","SITEID":"USA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.73445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 11:44:23","TRTEDTM":"2022-07-29 05:44:23","TRT01SDTM":"2019-07-29 11:44:23","TRT01EDTM":"2021-07-28 23:44:23","TRT02SDTM":"2021-07-28 23:44:23","TRT02EDTM":"2022-07-29 05:44:23","AP01SDTM":"2019-07-29 11:44:23","AP01EDTM":"2021-07-28 23:44:23","AP02SDTM":"2021-07-28 23:44:23","AP02EDTM":"2022-07-29 05:44:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-26","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4364,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.76177,"AVALU":"g/L","BASE2":3.05702,"BASE":2.9765,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.29525,"PCHG2":-9.65805,"CHG":-0.21473,"PCHG":-7.21408,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-23 11:44:23","ADY":878,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-320","SUBJID":"id-320","SITEID":"USA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.73445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 11:44:23","TRTEDTM":"2022-07-29 05:44:23","TRT01SDTM":"2019-07-29 11:44:23","TRT01EDTM":"2021-07-28 23:44:23","TRT02SDTM":"2021-07-28 23:44:23","TRT02EDTM":"2022-07-29 05:44:23","AP01SDTM":"2019-07-29 11:44:23","AP01EDTM":"2021-07-28 23:44:23","AP02SDTM":"2021-07-28 23:44:23","AP02EDTM":"2022-07-29 05:44:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-26","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7227,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96804,"AVALU":"g/L","BASE2":3.05702,"BASE":2.9765,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08898,"PCHG2":-2.9106,"CHG":-0.00846,"PCHG":-0.2841,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-27 11:44:23","ADY":882,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-320","SUBJID":"id-320","SITEID":"USA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.73445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 11:44:23","TRTEDTM":"2022-07-29 05:44:23","TRT01SDTM":"2019-07-29 11:44:23","TRT01EDTM":"2021-07-28 23:44:23","TRT02SDTM":"2021-07-28 23:44:23","TRT02EDTM":"2022-07-29 05:44:23","AP01SDTM":"2019-07-29 11:44:23","AP01EDTM":"2021-07-28 23:44:23","AP02SDTM":"2021-07-28 23:44:23","AP02EDTM":"2022-07-29 05:44:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-26","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2762,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79206,"AVALU":"g/L","BASE2":3.05702,"BASE":2.9765,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.26497,"PCHG2":-8.66743,"CHG":-0.18444,"PCHG":-6.19666,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-03-24 11:44:23","ADY":969,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-3-id-320","SUBJID":"id-320","SITEID":"USA-3","AGE":42,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-3","INVNAM":"Dr. USA-3 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":4.73445,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-07-26","TRTSDTM":"2019-07-29 11:44:23","TRTEDTM":"2022-07-29 05:44:23","TRT01SDTM":"2019-07-29 11:44:23","TRT01EDTM":"2021-07-28 23:44:23","TRT02SDTM":"2021-07-28 23:44:23","TRT02EDTM":"2022-07-29 05:44:23","AP01SDTM":"2019-07-29 11:44:23","AP01EDTM":"2021-07-28 23:44:23","AP02SDTM":"2021-07-28 23:44:23","AP02EDTM":"2022-07-29 05:44:23","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-29","EOSDY":1096,"LSTALVDT":"2022-08-26","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5742,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95086,"AVALU":"g/L","BASE2":3.05702,"BASE":2.9765,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.10616,"PCHG2":-3.47273,"CHG":-0.02564,"PCHG":-0.86143,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-22 11:44:23","ADY":1028,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-190","SUBJID":"id-190","SITEID":"USA-4","AGE":53,"AGEU":"YEARS","SEX":"M","RACE":"MULTIPLE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":1.14956,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-29","TRTSDTM":"2019-10-29 14:54:10","TRT01SDTM":"2019-10-29 14:54:10","AP01SDTM":"2019-10-29 14:54:10","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4616,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.6016,"AVALU":"U/L","BASE2":18.6016,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-03 14:54:10","ADY":35,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-190","SUBJID":"id-190","SITEID":"USA-4","AGE":53,"AGEU":"YEARS","SEX":"M","RACE":"MULTIPLE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":1.14956,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-29","TRTSDTM":"2019-10-29 14:54:10","TRT01SDTM":"2019-10-29 14:54:10","AP01SDTM":"2019-10-29 14:54:10","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6575,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":12.27977,"AVALU":"U/L","BASE2":18.6016,"BASE":12.27977,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-6.32183,"PCHG2":-33.98541,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-08 14:54:10","ADY":192,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-190","SUBJID":"id-190","SITEID":"USA-4","AGE":53,"AGEU":"YEARS","SEX":"M","RACE":"MULTIPLE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":1.14956,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-29","TRTSDTM":"2019-10-29 14:54:10","TRT01SDTM":"2019-10-29 14:54:10","AP01SDTM":"2019-10-29 14:54:10","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4945,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.05057,"AVALU":"U/L","BASE2":18.6016,"BASE":12.27977,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.55104,"PCHG2":-13.71408,"CHG":3.77079,"PCHG":30.70735,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-29 14:54:10","ADY":274,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-190","SUBJID":"id-190","SITEID":"USA-4","AGE":53,"AGEU":"YEARS","SEX":"M","RACE":"MULTIPLE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":1.14956,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-29","TRTSDTM":"2019-10-29 14:54:10","TRT01SDTM":"2019-10-29 14:54:10","AP01SDTM":"2019-10-29 14:54:10","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7252,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":19.42137,"AVALU":"U/L","BASE2":18.6016,"BASE":12.27977,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.81976,"PCHG2":4.40695,"CHG":7.1416,"PCHG":58.15739,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-25 14:54:10","ADY":301,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-190","SUBJID":"id-190","SITEID":"USA-4","AGE":53,"AGEU":"YEARS","SEX":"M","RACE":"MULTIPLE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":1.14956,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-29","TRTSDTM":"2019-10-29 14:54:10","TRT01SDTM":"2019-10-29 14:54:10","AP01SDTM":"2019-10-29 14:54:10","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4477,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.80085,"AVALU":"U/L","BASE2":18.6016,"BASE":12.27977,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.80075,"PCHG2":-79.56707,"CHG":-8.47892,"PCHG":-69.04786,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-09-21 14:54:10","ADY":328,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-190","SUBJID":"id-190","SITEID":"USA-4","AGE":53,"AGEU":"YEARS","SEX":"M","RACE":"MULTIPLE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":1.14956,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-29","TRTSDTM":"2019-10-29 14:54:10","TRT01SDTM":"2019-10-29 14:54:10","AP01SDTM":"2019-10-29 14:54:10","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2610,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":40.83016,"AVALU":"U/L","BASE2":18.6016,"BASE":12.27977,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":22.22856,"PCHG2":119.49806,"CHG":28.55039,"PCHG":232.49931,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-19 14:54:10","ADY":448,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-190","SUBJID":"id-190","SITEID":"USA-4","AGE":53,"AGEU":"YEARS","SEX":"M","RACE":"MULTIPLE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":1.14956,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-29","TRTSDTM":"2019-10-29 14:54:10","TRT01SDTM":"2019-10-29 14:54:10","AP01SDTM":"2019-10-29 14:54:10","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6664,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.42141,"AVALU":"U/L","BASE2":18.6016,"BASE":12.27977,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.1802,"PCHG2":-76.23105,"CHG":-7.85837,"PCHG":-63.9944,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-04-29 14:54:10","ADY":548,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-190","SUBJID":"id-190","SITEID":"USA-4","AGE":53,"AGEU":"YEARS","SEX":"M","RACE":"MULTIPLE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":1.14956,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-29","TRTSDTM":"2019-10-29 14:54:10","TRT01SDTM":"2019-10-29 14:54:10","AP01SDTM":"2019-10-29 14:54:10","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2369,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.00969,"AVALU":"mg/L","BASE2":10.00969,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"3","BTOXGR":"0","ADTM":"2019-12-03 14:54:10","ADY":35,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-190","SUBJID":"id-190","SITEID":"USA-4","AGE":53,"AGEU":"YEARS","SEX":"M","RACE":"MULTIPLE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":1.14956,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-29","TRTSDTM":"2019-10-29 14:54:10","TRT01SDTM":"2019-10-29 14:54:10","AP01SDTM":"2019-10-29 14:54:10","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6014,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.55731,"AVALU":"mg/L","BASE2":10.00969,"BASE":9.55731,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.45237,"PCHG2":-4.51935,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-08 14:54:10","ADY":192,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-190","SUBJID":"id-190","SITEID":"USA-4","AGE":53,"AGEU":"YEARS","SEX":"M","RACE":"MULTIPLE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":1.14956,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-29","TRTSDTM":"2019-10-29 14:54:10","TRT01SDTM":"2019-10-29 14:54:10","AP01SDTM":"2019-10-29 14:54:10","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1318,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.03306,"AVALU":"mg/L","BASE2":10.00969,"BASE":9.55731,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.97662,"PCHG2":-19.74711,"CHG":-1.52425,"PCHG":-15.94853,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-29 14:54:10","ADY":274,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-190","SUBJID":"id-190","SITEID":"USA-4","AGE":53,"AGEU":"YEARS","SEX":"M","RACE":"MULTIPLE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":1.14956,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-29","TRTSDTM":"2019-10-29 14:54:10","TRT01SDTM":"2019-10-29 14:54:10","AP01SDTM":"2019-10-29 14:54:10","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7781,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.35217,"AVALU":"mg/L","BASE2":10.00969,"BASE":9.55731,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.65752,"PCHG2":-6.56881,"CHG":-0.20514,"PCHG":-2.14647,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-25 14:54:10","ADY":301,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-190","SUBJID":"id-190","SITEID":"USA-4","AGE":53,"AGEU":"YEARS","SEX":"M","RACE":"MULTIPLE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":1.14956,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-29","TRTSDTM":"2019-10-29 14:54:10","TRT01SDTM":"2019-10-29 14:54:10","AP01SDTM":"2019-10-29 14:54:10","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5947,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.5228,"AVALU":"mg/L","BASE2":10.00969,"BASE":9.55731,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.48689,"PCHG2":-4.86418,"CHG":-0.03452,"PCHG":-0.36115,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-21 14:54:10","ADY":328,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-190","SUBJID":"id-190","SITEID":"USA-4","AGE":53,"AGEU":"YEARS","SEX":"M","RACE":"MULTIPLE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":1.14956,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-29","TRTSDTM":"2019-10-29 14:54:10","TRT01SDTM":"2019-10-29 14:54:10","AP01SDTM":"2019-10-29 14:54:10","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4878,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.65714,"AVALU":"mg/L","BASE2":10.00969,"BASE":9.55731,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.35254,"PCHG2":-3.52203,"CHG":0.09983,"PCHG":1.04453,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-19 14:54:10","ADY":448,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-190","SUBJID":"id-190","SITEID":"USA-4","AGE":53,"AGEU":"YEARS","SEX":"M","RACE":"MULTIPLE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":1.14956,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-29","TRTSDTM":"2019-10-29 14:54:10","TRT01SDTM":"2019-10-29 14:54:10","AP01SDTM":"2019-10-29 14:54:10","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8378,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.97331,"AVALU":"mg/L","BASE2":10.00969,"BASE":9.55731,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.03637,"PCHG2":-20.34404,"CHG":-1.584,"PCHG":-16.57372,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-04-29 14:54:10","ADY":548,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-190","SUBJID":"id-190","SITEID":"USA-4","AGE":53,"AGEU":"YEARS","SEX":"M","RACE":"MULTIPLE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":1.14956,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-29","TRTSDTM":"2019-10-29 14:54:10","TRT01SDTM":"2019-10-29 14:54:10","AP01SDTM":"2019-10-29 14:54:10","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6376,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.8194,"AVALU":"g/L","BASE2":2.8194,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-12-03 14:54:10","ADY":35,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-190","SUBJID":"id-190","SITEID":"USA-4","AGE":53,"AGEU":"YEARS","SEX":"M","RACE":"MULTIPLE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":1.14956,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-29","TRTSDTM":"2019-10-29 14:54:10","TRT01SDTM":"2019-10-29 14:54:10","AP01SDTM":"2019-10-29 14:54:10","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2949,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88339,"AVALU":"g/L","BASE2":2.8194,"BASE":2.88339,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.06399,"PCHG2":2.26964,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-05-08 14:54:10","ADY":192,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-190","SUBJID":"id-190","SITEID":"USA-4","AGE":53,"AGEU":"YEARS","SEX":"M","RACE":"MULTIPLE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":1.14956,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-29","TRTSDTM":"2019-10-29 14:54:10","TRT01SDTM":"2019-10-29 14:54:10","AP01SDTM":"2019-10-29 14:54:10","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5758,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96441,"AVALU":"g/L","BASE2":2.8194,"BASE":2.88339,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.145,"PCHG2":5.14306,"CHG":0.08101,"PCHG":2.80965,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-07-29 14:54:10","ADY":274,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-190","SUBJID":"id-190","SITEID":"USA-4","AGE":53,"AGEU":"YEARS","SEX":"M","RACE":"MULTIPLE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":1.14956,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-29","TRTSDTM":"2019-10-29 14:54:10","TRT01SDTM":"2019-10-29 14:54:10","AP01SDTM":"2019-10-29 14:54:10","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6070,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92668,"AVALU":"g/L","BASE2":2.8194,"BASE":2.88339,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10728,"PCHG2":3.80498,"CHG":0.04329,"PCHG":1.50126,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-25 14:54:10","ADY":301,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-190","SUBJID":"id-190","SITEID":"USA-4","AGE":53,"AGEU":"YEARS","SEX":"M","RACE":"MULTIPLE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":1.14956,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-29","TRTSDTM":"2019-10-29 14:54:10","TRT01SDTM":"2019-10-29 14:54:10","AP01SDTM":"2019-10-29 14:54:10","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7144,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81635,"AVALU":"g/L","BASE2":2.8194,"BASE":2.88339,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00305,"PCHG2":-0.10814,"CHG":-0.06704,"PCHG":-2.32501,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-21 14:54:10","ADY":328,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-190","SUBJID":"id-190","SITEID":"USA-4","AGE":53,"AGEU":"YEARS","SEX":"M","RACE":"MULTIPLE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":1.14956,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-29","TRTSDTM":"2019-10-29 14:54:10","TRT01SDTM":"2019-10-29 14:54:10","AP01SDTM":"2019-10-29 14:54:10","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3786,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.84886,"AVALU":"g/L","BASE2":2.8194,"BASE":2.88339,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02945,"PCHG2":1.04463,"CHG":-0.03454,"PCHG":-1.19783,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-19 14:54:10","ADY":448,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-190","SUBJID":"id-190","SITEID":"USA-4","AGE":53,"AGEU":"YEARS","SEX":"M","RACE":"MULTIPLE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S2","BMRKR1":1.14956,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-10-29","TRTSDTM":"2019-10-29 14:54:10","TRT01SDTM":"2019-10-29 14:54:10","AP01SDTM":"2019-10-29 14:54:10","EOSSTT":"ONGOING","EOTSTT":"ONGOING","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1559,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92868,"AVALU":"g/L","BASE2":2.8194,"BASE":2.88339,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10927,"PCHG2":3.87581,"CHG":0.04528,"PCHG":1.57052,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-29 14:54:10","ADY":548,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-382","SUBJID":"id-382","SITEID":"USA-4","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":7.94871,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-01","TRTSDTM":"2019-09-03 10:47:51","TRTEDTM":"2022-02-17 18:00:34","TRT01SDTM":"2019-09-03 10:47:51","TRT01EDTM":"2021-02-17 12:00:34","TRT02SDTM":"2021-02-17 12:00:34","TRT02EDTM":"2022-02-17 18:00:34","AP01SDTM":"2019-09-03 10:47:51","AP01EDTM":"2021-02-17 12:00:34","AP02SDTM":"2021-02-17 12:00:34","AP02EDTM":"2022-02-17 18:00:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":899,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":909,"ADTHAUT":"Yes","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4653,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":29.60403,"AVALU":"U/L","BASE2":29.60403,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-29 10:47:51","ADY":179,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-382","SUBJID":"id-382","SITEID":"USA-4","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":7.94871,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-01","TRTSDTM":"2019-09-03 10:47:51","TRTEDTM":"2022-02-17 18:00:34","TRT01SDTM":"2019-09-03 10:47:51","TRT01EDTM":"2021-02-17 12:00:34","TRT02SDTM":"2021-02-17 12:00:34","TRT02EDTM":"2022-02-17 18:00:34","AP01SDTM":"2019-09-03 10:47:51","AP01EDTM":"2021-02-17 12:00:34","AP02SDTM":"2021-02-17 12:00:34","AP02EDTM":"2022-02-17 18:00:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":899,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":909,"ADTHAUT":"Yes","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1601,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":22.97722,"AVALU":"U/L","BASE2":29.60403,"BASE":22.97722,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-6.6268,"PCHG2":-22.38481,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-25 10:47:51","ADY":479,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-382","SUBJID":"id-382","SITEID":"USA-4","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":7.94871,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-01","TRTSDTM":"2019-09-03 10:47:51","TRTEDTM":"2022-02-17 18:00:34","TRT01SDTM":"2019-09-03 10:47:51","TRT01EDTM":"2021-02-17 12:00:34","TRT02SDTM":"2021-02-17 12:00:34","TRT02EDTM":"2022-02-17 18:00:34","AP01SDTM":"2019-09-03 10:47:51","AP01EDTM":"2021-02-17 12:00:34","AP02SDTM":"2021-02-17 12:00:34","AP02EDTM":"2022-02-17 18:00:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":899,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":909,"ADTHAUT":"Yes","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1968,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.49813,"AVALU":"U/L","BASE2":29.60403,"BASE":22.97722,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.1059,"PCHG2":-44.27066,"CHG":-6.47909,"PCHG":-28.19789,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-25 10:47:51","ADY":510,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-382","SUBJID":"id-382","SITEID":"USA-4","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":7.94871,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-01","TRTSDTM":"2019-09-03 10:47:51","TRTEDTM":"2022-02-17 18:00:34","TRT01SDTM":"2019-09-03 10:47:51","TRT01EDTM":"2021-02-17 12:00:34","TRT02SDTM":"2021-02-17 12:00:34","TRT02EDTM":"2022-02-17 18:00:34","AP01SDTM":"2019-09-03 10:47:51","AP01EDTM":"2021-02-17 12:00:34","AP02SDTM":"2021-02-17 12:00:34","AP02EDTM":"2022-02-17 18:00:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":899,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":909,"ADTHAUT":"Yes","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3429,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.53099,"AVALU":"U/L","BASE2":29.60403,"BASE":22.97722,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-11.07303,"PCHG2":-37.40381,"CHG":-4.44623,"PCHG":-19.3506,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-23 10:47:51","ADY":539,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-382","SUBJID":"id-382","SITEID":"USA-4","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":7.94871,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-01","TRTSDTM":"2019-09-03 10:47:51","TRTEDTM":"2022-02-17 18:00:34","TRT01SDTM":"2019-09-03 10:47:51","TRT01EDTM":"2021-02-17 12:00:34","TRT02SDTM":"2021-02-17 12:00:34","TRT02EDTM":"2022-02-17 18:00:34","AP01SDTM":"2019-09-03 10:47:51","AP01EDTM":"2021-02-17 12:00:34","AP02SDTM":"2021-02-17 12:00:34","AP02EDTM":"2022-02-17 18:00:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":899,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":909,"ADTHAUT":"Yes","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2583,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.49163,"AVALU":"U/L","BASE2":29.60403,"BASE":22.97722,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-27.1124,"PCHG2":-91.58349,"CHG":-20.4856,"PCHG":-89.1561,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-05-06 10:47:51","ADY":611,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-382","SUBJID":"id-382","SITEID":"USA-4","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":7.94871,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-01","TRTSDTM":"2019-09-03 10:47:51","TRTEDTM":"2022-02-17 18:00:34","TRT01SDTM":"2019-09-03 10:47:51","TRT01EDTM":"2021-02-17 12:00:34","TRT02SDTM":"2021-02-17 12:00:34","TRT02EDTM":"2022-02-17 18:00:34","AP01SDTM":"2019-09-03 10:47:51","AP01EDTM":"2021-02-17 12:00:34","AP02SDTM":"2021-02-17 12:00:34","AP02EDTM":"2022-02-17 18:00:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":899,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":909,"ADTHAUT":"Yes","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4154,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.53024,"AVALU":"U/L","BASE2":29.60403,"BASE":22.97722,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-29.07378,"PCHG2":-98.20888,"CHG":-22.44698,"PCHG":-97.69231,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-07-30 10:47:51","ADY":696,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-382","SUBJID":"id-382","SITEID":"USA-4","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":7.94871,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-01","TRTSDTM":"2019-09-03 10:47:51","TRTEDTM":"2022-02-17 18:00:34","TRT01SDTM":"2019-09-03 10:47:51","TRT01EDTM":"2021-02-17 12:00:34","TRT02SDTM":"2021-02-17 12:00:34","TRT02EDTM":"2022-02-17 18:00:34","AP01SDTM":"2019-09-03 10:47:51","AP01EDTM":"2021-02-17 12:00:34","AP02SDTM":"2021-02-17 12:00:34","AP02EDTM":"2022-02-17 18:00:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":899,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":909,"ADTHAUT":"Yes","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4389,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":0.51713,"AVALU":"U/L","BASE2":29.60403,"BASE":22.97722,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-29.0869,"PCHG2":-98.25319,"CHG":-22.4601,"PCHG":-97.7494,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2022-01-08 10:47:51","ADY":858,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-382","SUBJID":"id-382","SITEID":"USA-4","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":7.94871,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-01","TRTSDTM":"2019-09-03 10:47:51","TRTEDTM":"2022-02-17 18:00:34","TRT01SDTM":"2019-09-03 10:47:51","TRT01EDTM":"2021-02-17 12:00:34","TRT02SDTM":"2021-02-17 12:00:34","TRT02EDTM":"2022-02-17 18:00:34","AP01SDTM":"2019-09-03 10:47:51","AP01EDTM":"2021-02-17 12:00:34","AP02SDTM":"2021-02-17 12:00:34","AP02EDTM":"2022-02-17 18:00:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":899,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":909,"ADTHAUT":"Yes","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":834,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.4863,"AVALU":"mg/L","BASE2":9.4863,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-29 10:47:51","ADY":179,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-382","SUBJID":"id-382","SITEID":"USA-4","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":7.94871,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-01","TRTSDTM":"2019-09-03 10:47:51","TRTEDTM":"2022-02-17 18:00:34","TRT01SDTM":"2019-09-03 10:47:51","TRT01EDTM":"2021-02-17 12:00:34","TRT02SDTM":"2021-02-17 12:00:34","TRT02EDTM":"2022-02-17 18:00:34","AP01SDTM":"2019-09-03 10:47:51","AP01EDTM":"2021-02-17 12:00:34","AP02SDTM":"2021-02-17 12:00:34","AP02EDTM":"2022-02-17 18:00:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":899,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":909,"ADTHAUT":"Yes","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1418,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.98365,"AVALU":"mg/L","BASE2":9.4863,"BASE":8.98365,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.50266,"PCHG2":-5.29876,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-25 10:47:51","ADY":479,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-382","SUBJID":"id-382","SITEID":"USA-4","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":7.94871,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-01","TRTSDTM":"2019-09-03 10:47:51","TRTEDTM":"2022-02-17 18:00:34","TRT01SDTM":"2019-09-03 10:47:51","TRT01EDTM":"2021-02-17 12:00:34","TRT02SDTM":"2021-02-17 12:00:34","TRT02EDTM":"2022-02-17 18:00:34","AP01SDTM":"2019-09-03 10:47:51","AP01EDTM":"2021-02-17 12:00:34","AP02SDTM":"2021-02-17 12:00:34","AP02EDTM":"2022-02-17 18:00:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":899,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":909,"ADTHAUT":"Yes","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1310,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.74497,"AVALU":"mg/L","BASE2":9.4863,"BASE":8.98365,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.74134,"PCHG2":-18.35634,"CHG":-1.23868,"PCHG":-13.78818,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-01-25 10:47:51","ADY":510,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-382","SUBJID":"id-382","SITEID":"USA-4","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":7.94871,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-01","TRTSDTM":"2019-09-03 10:47:51","TRTEDTM":"2022-02-17 18:00:34","TRT01SDTM":"2019-09-03 10:47:51","TRT01EDTM":"2021-02-17 12:00:34","TRT02SDTM":"2021-02-17 12:00:34","TRT02EDTM":"2022-02-17 18:00:34","AP01SDTM":"2019-09-03 10:47:51","AP01EDTM":"2021-02-17 12:00:34","AP02SDTM":"2021-02-17 12:00:34","AP02EDTM":"2022-02-17 18:00:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":899,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":909,"ADTHAUT":"Yes","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5066,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.69408,"AVALU":"mg/L","BASE2":9.4863,"BASE":8.98365,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.79223,"PCHG2":-8.35129,"CHG":-0.28957,"PCHG":-3.22332,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-23 10:47:51","ADY":539,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-382","SUBJID":"id-382","SITEID":"USA-4","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":7.94871,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-01","TRTSDTM":"2019-09-03 10:47:51","TRTEDTM":"2022-02-17 18:00:34","TRT01SDTM":"2019-09-03 10:47:51","TRT01EDTM":"2021-02-17 12:00:34","TRT02SDTM":"2021-02-17 12:00:34","TRT02EDTM":"2022-02-17 18:00:34","AP01SDTM":"2019-09-03 10:47:51","AP01EDTM":"2021-02-17 12:00:34","AP02SDTM":"2021-02-17 12:00:34","AP02EDTM":"2022-02-17 18:00:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":899,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":909,"ADTHAUT":"Yes","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7344,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.82802,"AVALU":"mg/L","BASE2":9.4863,"BASE":8.98365,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.34172,"PCHG2":3.60221,"CHG":0.84437,"PCHG":9.399,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-06 10:47:51","ADY":611,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-382","SUBJID":"id-382","SITEID":"USA-4","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":7.94871,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-01","TRTSDTM":"2019-09-03 10:47:51","TRTEDTM":"2022-02-17 18:00:34","TRT01SDTM":"2019-09-03 10:47:51","TRT01EDTM":"2021-02-17 12:00:34","TRT02SDTM":"2021-02-17 12:00:34","TRT02EDTM":"2022-02-17 18:00:34","AP01SDTM":"2019-09-03 10:47:51","AP01EDTM":"2021-02-17 12:00:34","AP02SDTM":"2021-02-17 12:00:34","AP02EDTM":"2022-02-17 18:00:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":899,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":909,"ADTHAUT":"Yes","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1864,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.40276,"AVALU":"mg/L","BASE2":9.4863,"BASE":8.98365,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08354,"PCHG2":-0.88067,"CHG":0.41911,"PCHG":4.6653,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-30 10:47:51","ADY":696,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-382","SUBJID":"id-382","SITEID":"USA-4","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":7.94871,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-01","TRTSDTM":"2019-09-03 10:47:51","TRTEDTM":"2022-02-17 18:00:34","TRT01SDTM":"2019-09-03 10:47:51","TRT01EDTM":"2021-02-17 12:00:34","TRT02SDTM":"2021-02-17 12:00:34","TRT02EDTM":"2022-02-17 18:00:34","AP01SDTM":"2019-09-03 10:47:51","AP01EDTM":"2021-02-17 12:00:34","AP02SDTM":"2021-02-17 12:00:34","AP02EDTM":"2022-02-17 18:00:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":899,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":909,"ADTHAUT":"Yes","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1831,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.23669,"AVALU":"mg/L","BASE2":9.4863,"BASE":8.98365,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.75038,"PCHG2":7.91017,"CHG":1.25304,"PCHG":13.948,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"1","BTOXGR":"0","ADTM":"2022-01-08 10:47:51","ADY":858,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-382","SUBJID":"id-382","SITEID":"USA-4","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":7.94871,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-01","TRTSDTM":"2019-09-03 10:47:51","TRTEDTM":"2022-02-17 18:00:34","TRT01SDTM":"2019-09-03 10:47:51","TRT01EDTM":"2021-02-17 12:00:34","TRT02SDTM":"2021-02-17 12:00:34","TRT02EDTM":"2022-02-17 18:00:34","AP01SDTM":"2019-09-03 10:47:51","AP01EDTM":"2021-02-17 12:00:34","AP02SDTM":"2021-02-17 12:00:34","AP02EDTM":"2022-02-17 18:00:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":899,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":909,"ADTHAUT":"Yes","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8394,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82536,"AVALU":"g/L","BASE2":2.82536,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-29 10:47:51","ADY":179,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-382","SUBJID":"id-382","SITEID":"USA-4","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":7.94871,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-01","TRTSDTM":"2019-09-03 10:47:51","TRTEDTM":"2022-02-17 18:00:34","TRT01SDTM":"2019-09-03 10:47:51","TRT01EDTM":"2021-02-17 12:00:34","TRT02SDTM":"2021-02-17 12:00:34","TRT02EDTM":"2022-02-17 18:00:34","AP01SDTM":"2019-09-03 10:47:51","AP01EDTM":"2021-02-17 12:00:34","AP02SDTM":"2021-02-17 12:00:34","AP02EDTM":"2022-02-17 18:00:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":899,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":909,"ADTHAUT":"Yes","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6908,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95256,"AVALU":"g/L","BASE2":2.82536,"BASE":2.95256,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.1272,"PCHG2":4.50212,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-25 10:47:51","ADY":479,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-382","SUBJID":"id-382","SITEID":"USA-4","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":7.94871,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-01","TRTSDTM":"2019-09-03 10:47:51","TRTEDTM":"2022-02-17 18:00:34","TRT01SDTM":"2019-09-03 10:47:51","TRT01EDTM":"2021-02-17 12:00:34","TRT02SDTM":"2021-02-17 12:00:34","TRT02EDTM":"2022-02-17 18:00:34","AP01SDTM":"2019-09-03 10:47:51","AP01EDTM":"2021-02-17 12:00:34","AP02SDTM":"2021-02-17 12:00:34","AP02EDTM":"2022-02-17 18:00:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":899,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":909,"ADTHAUT":"Yes","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6413,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9101,"AVALU":"g/L","BASE2":2.82536,"BASE":2.95256,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.08474,"PCHG2":2.99938,"CHG":-0.04246,"PCHG":-1.438,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-25 10:47:51","ADY":510,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-382","SUBJID":"id-382","SITEID":"USA-4","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":7.94871,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-01","TRTSDTM":"2019-09-03 10:47:51","TRTEDTM":"2022-02-17 18:00:34","TRT01SDTM":"2019-09-03 10:47:51","TRT01EDTM":"2021-02-17 12:00:34","TRT02SDTM":"2021-02-17 12:00:34","TRT02EDTM":"2022-02-17 18:00:34","AP01SDTM":"2019-09-03 10:47:51","AP01EDTM":"2021-02-17 12:00:34","AP02SDTM":"2021-02-17 12:00:34","AP02EDTM":"2022-02-17 18:00:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":899,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":909,"ADTHAUT":"Yes","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7843,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96696,"AVALU":"g/L","BASE2":2.82536,"BASE":2.95256,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.14161,"PCHG2":5.01202,"CHG":0.01441,"PCHG":0.48793,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-23 10:47:51","ADY":539,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-382","SUBJID":"id-382","SITEID":"USA-4","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":7.94871,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-01","TRTSDTM":"2019-09-03 10:47:51","TRTEDTM":"2022-02-17 18:00:34","TRT01SDTM":"2019-09-03 10:47:51","TRT01EDTM":"2021-02-17 12:00:34","TRT02SDTM":"2021-02-17 12:00:34","TRT02EDTM":"2022-02-17 18:00:34","AP01SDTM":"2019-09-03 10:47:51","AP01EDTM":"2021-02-17 12:00:34","AP02SDTM":"2021-02-17 12:00:34","AP02EDTM":"2022-02-17 18:00:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":899,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":909,"ADTHAUT":"Yes","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1846,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80981,"AVALU":"g/L","BASE2":2.82536,"BASE":2.95256,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01554,"PCHG2":-0.55009,"CHG":-0.14274,"PCHG":-4.83455,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-06 10:47:51","ADY":611,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-382","SUBJID":"id-382","SITEID":"USA-4","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":7.94871,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-01","TRTSDTM":"2019-09-03 10:47:51","TRTEDTM":"2022-02-17 18:00:34","TRT01SDTM":"2019-09-03 10:47:51","TRT01EDTM":"2021-02-17 12:00:34","TRT02SDTM":"2021-02-17 12:00:34","TRT02EDTM":"2022-02-17 18:00:34","AP01SDTM":"2019-09-03 10:47:51","AP01EDTM":"2021-02-17 12:00:34","AP02SDTM":"2021-02-17 12:00:34","AP02EDTM":"2022-02-17 18:00:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":899,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":909,"ADTHAUT":"Yes","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6056,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.93146,"AVALU":"g/L","BASE2":2.82536,"BASE":2.95256,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.10611,"PCHG2":3.75556,"CHG":-0.02109,"PCHG":-0.71439,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-30 10:47:51","ADY":696,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-4-id-382","SUBJID":"id-382","SITEID":"USA-4","AGE":31,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"Y","INVID":"INV ID USA-4","INVNAM":"Dr. USA-4 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"A: Drug X","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":7.94871,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2019-09-01","TRTSDTM":"2019-09-03 10:47:51","TRTEDTM":"2022-02-17 18:00:34","TRT01SDTM":"2019-09-03 10:47:51","TRT01EDTM":"2021-02-17 12:00:34","TRT02SDTM":"2021-02-17 12:00:34","TRT02EDTM":"2022-02-17 18:00:34","AP01SDTM":"2019-09-03 10:47:51","AP01EDTM":"2021-02-17 12:00:34","AP02SDTM":"2021-02-17 12:00:34","AP02EDTM":"2022-02-17 18:00:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-17","EOSDY":899,"DCSREAS":"DEATH","DTHDT":"2022-03-01","DTHCAUS":"ADVERSE EVENT","DTHCAT":"ADVERSE EVENT","LDDTHELD":12,"LDDTHGR1":"<=30","LSTALVDT":"2022-03-01","DTHADY":909,"ADTHAUT":"Yes","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3749,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.06355,"AVALU":"g/L","BASE2":2.82536,"BASE":2.95256,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.23819,"PCHG2":8.4305,"CHG":0.11099,"PCHG":3.75915,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"NORMAL to HIGH","ATOXGR":"2","BTOXGR":"0","ADTM":"2022-01-08 10:47:51","ADY":858,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-5-id-179","SUBJID":"id-179","SITEID":"USA-5","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-5","INVNAM":"Dr. USA-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":4.67743,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-08 02:16:02","TRTEDTM":"2022-02-14 08:20:34","TRT01SDTM":"2020-09-08 02:16:02","TRT01EDTM":"2021-02-14 02:20:34","TRT02SDTM":"2021-02-14 02:20:34","TRT02EDTM":"2022-02-14 08:20:34","AP01SDTM":"2020-09-08 02:16:02","AP01EDTM":"2021-02-14 02:20:34","AP02SDTM":"2021-02-14 02:20:34","AP02EDTM":"2022-02-14 08:20:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":525,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-02-25","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4165,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.75452,"AVALU":"U/L","BASE2":7.75452,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-29 02:16:02","ADY":143,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-5-id-179","SUBJID":"id-179","SITEID":"USA-5","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-5","INVNAM":"Dr. USA-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":4.67743,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-08 02:16:02","TRTEDTM":"2022-02-14 08:20:34","TRT01SDTM":"2020-09-08 02:16:02","TRT01EDTM":"2021-02-14 02:20:34","TRT02SDTM":"2021-02-14 02:20:34","TRT02EDTM":"2022-02-14 08:20:34","AP01SDTM":"2020-09-08 02:16:02","AP01EDTM":"2021-02-14 02:20:34","AP02SDTM":"2021-02-14 02:20:34","AP02EDTM":"2022-02-14 08:20:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":525,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-02-25","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":6038,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.96534,"AVALU":"U/L","BASE2":7.75452,"BASE":16.96534,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":9.21082,"PCHG2":118.78013,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-20 02:16:02","ADY":165,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-5-id-179","SUBJID":"id-179","SITEID":"USA-5","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-5","INVNAM":"Dr. USA-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":4.67743,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-08 02:16:02","TRTEDTM":"2022-02-14 08:20:34","TRT01SDTM":"2020-09-08 02:16:02","TRT01EDTM":"2021-02-14 02:20:34","TRT02SDTM":"2021-02-14 02:20:34","TRT02EDTM":"2022-02-14 08:20:34","AP01SDTM":"2020-09-08 02:16:02","AP01EDTM":"2021-02-14 02:20:34","AP02SDTM":"2021-02-14 02:20:34","AP02EDTM":"2022-02-14 08:20:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":525,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-02-25","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2503,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.45264,"AVALU":"U/L","BASE2":7.75452,"BASE":16.96534,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.69812,"PCHG2":73.48135,"CHG":-3.5127,"PCHG":-20.70516,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-26 02:16:02","ADY":230,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-5-id-179","SUBJID":"id-179","SITEID":"USA-5","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-5","INVNAM":"Dr. USA-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":4.67743,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-08 02:16:02","TRTEDTM":"2022-02-14 08:20:34","TRT01SDTM":"2020-09-08 02:16:02","TRT01EDTM":"2021-02-14 02:20:34","TRT02SDTM":"2021-02-14 02:20:34","TRT02EDTM":"2022-02-14 08:20:34","AP01SDTM":"2020-09-08 02:16:02","AP01EDTM":"2021-02-14 02:20:34","AP02SDTM":"2021-02-14 02:20:34","AP02EDTM":"2022-02-14 08:20:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":525,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-02-25","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7282,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.4193,"AVALU":"U/L","BASE2":7.75452,"BASE":16.96534,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":5.66479,"PCHG2":73.05146,"CHG":-3.54604,"PCHG":-20.90166,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-15 02:16:02","ADY":249,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-5-id-179","SUBJID":"id-179","SITEID":"USA-5","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-5","INVNAM":"Dr. USA-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":4.67743,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-08 02:16:02","TRTEDTM":"2022-02-14 08:20:34","TRT01SDTM":"2020-09-08 02:16:02","TRT01EDTM":"2021-02-14 02:20:34","TRT02SDTM":"2021-02-14 02:20:34","TRT02EDTM":"2022-02-14 08:20:34","AP01SDTM":"2020-09-08 02:16:02","AP01EDTM":"2021-02-14 02:20:34","AP02SDTM":"2021-02-14 02:20:34","AP02EDTM":"2022-02-14 08:20:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":525,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-02-25","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7712,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.22076,"AVALU":"U/L","BASE2":7.75452,"BASE":16.96534,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":17.46625,"PCHG2":225.23971,"CHG":8.25542,"PCHG":48.66053,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-06 02:16:02","ADY":363,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-5-id-179","SUBJID":"id-179","SITEID":"USA-5","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-5","INVNAM":"Dr. USA-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":4.67743,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-08 02:16:02","TRTEDTM":"2022-02-14 08:20:34","TRT01SDTM":"2020-09-08 02:16:02","TRT01EDTM":"2021-02-14 02:20:34","TRT02SDTM":"2021-02-14 02:20:34","TRT02EDTM":"2022-02-14 08:20:34","AP01SDTM":"2020-09-08 02:16:02","AP01EDTM":"2021-02-14 02:20:34","AP02SDTM":"2021-02-14 02:20:34","AP02EDTM":"2022-02-14 08:20:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":525,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-02-25","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4227,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":30.25064,"AVALU":"U/L","BASE2":7.75452,"BASE":16.96534,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":22.49612,"PCHG2":290.10353,"CHG":13.2853,"PCHG":78.30848,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-01 02:16:02","ADY":449,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-5-id-179","SUBJID":"id-179","SITEID":"USA-5","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-5","INVNAM":"Dr. USA-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":4.67743,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-08 02:16:02","TRTEDTM":"2022-02-14 08:20:34","TRT01SDTM":"2020-09-08 02:16:02","TRT01EDTM":"2021-02-14 02:20:34","TRT02SDTM":"2021-02-14 02:20:34","TRT02EDTM":"2022-02-14 08:20:34","AP01SDTM":"2020-09-08 02:16:02","AP01EDTM":"2021-02-14 02:20:34","AP02SDTM":"2021-02-14 02:20:34","AP02EDTM":"2022-02-14 08:20:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":525,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-02-25","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4167,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":23.96899,"AVALU":"U/L","BASE2":7.75452,"BASE":16.96534,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":16.21447,"PCHG2":209.09719,"CHG":7.00365,"PCHG":41.28211,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-10 02:16:02","ADY":458,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-5-id-179","SUBJID":"id-179","SITEID":"USA-5","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-5","INVNAM":"Dr. USA-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":4.67743,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-08 02:16:02","TRTEDTM":"2022-02-14 08:20:34","TRT01SDTM":"2020-09-08 02:16:02","TRT01EDTM":"2021-02-14 02:20:34","TRT02SDTM":"2021-02-14 02:20:34","TRT02EDTM":"2022-02-14 08:20:34","AP01SDTM":"2020-09-08 02:16:02","AP01EDTM":"2021-02-14 02:20:34","AP02SDTM":"2021-02-14 02:20:34","AP02EDTM":"2022-02-14 08:20:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":525,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-02-25","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":363,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.32837,"AVALU":"mg/L","BASE2":9.32837,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-29 02:16:02","ADY":143,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-5-id-179","SUBJID":"id-179","SITEID":"USA-5","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-5","INVNAM":"Dr. USA-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":4.67743,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-08 02:16:02","TRTEDTM":"2022-02-14 08:20:34","TRT01SDTM":"2020-09-08 02:16:02","TRT01EDTM":"2021-02-14 02:20:34","TRT02SDTM":"2021-02-14 02:20:34","TRT02EDTM":"2022-02-14 08:20:34","AP01SDTM":"2020-09-08 02:16:02","AP01EDTM":"2021-02-14 02:20:34","AP02SDTM":"2021-02-14 02:20:34","AP02EDTM":"2022-02-14 08:20:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":525,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-02-25","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":6439,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.68927,"AVALU":"mg/L","BASE2":9.32837,"BASE":8.68927,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.6391,"PCHG2":-6.85117,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-20 02:16:02","ADY":165,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-5-id-179","SUBJID":"id-179","SITEID":"USA-5","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-5","INVNAM":"Dr. USA-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":4.67743,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-08 02:16:02","TRTEDTM":"2022-02-14 08:20:34","TRT01SDTM":"2020-09-08 02:16:02","TRT01EDTM":"2021-02-14 02:20:34","TRT02SDTM":"2021-02-14 02:20:34","TRT02EDTM":"2022-02-14 08:20:34","AP01SDTM":"2020-09-08 02:16:02","AP01EDTM":"2021-02-14 02:20:34","AP02SDTM":"2021-02-14 02:20:34","AP02EDTM":"2022-02-14 08:20:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":525,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-02-25","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4578,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.7317,"AVALU":"mg/L","BASE2":9.32837,"BASE":8.68927,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.59668,"PCHG2":-17.11635,"CHG":-0.95757,"PCHG":-11.02019,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-04-26 02:16:02","ADY":230,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-5-id-179","SUBJID":"id-179","SITEID":"USA-5","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-5","INVNAM":"Dr. USA-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":4.67743,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-08 02:16:02","TRTEDTM":"2022-02-14 08:20:34","TRT01SDTM":"2020-09-08 02:16:02","TRT01EDTM":"2021-02-14 02:20:34","TRT02SDTM":"2021-02-14 02:20:34","TRT02EDTM":"2022-02-14 08:20:34","AP01SDTM":"2020-09-08 02:16:02","AP01EDTM":"2021-02-14 02:20:34","AP02SDTM":"2021-02-14 02:20:34","AP02EDTM":"2022-02-14 08:20:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":525,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-02-25","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4030,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.06974,"AVALU":"mg/L","BASE2":9.32837,"BASE":8.68927,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.25864,"PCHG2":-2.77257,"CHG":0.38047,"PCHG":4.37858,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-15 02:16:02","ADY":249,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-5-id-179","SUBJID":"id-179","SITEID":"USA-5","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-5","INVNAM":"Dr. USA-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":4.67743,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-08 02:16:02","TRTEDTM":"2022-02-14 08:20:34","TRT01SDTM":"2020-09-08 02:16:02","TRT01EDTM":"2021-02-14 02:20:34","TRT02SDTM":"2021-02-14 02:20:34","TRT02EDTM":"2022-02-14 08:20:34","AP01SDTM":"2020-09-08 02:16:02","AP01EDTM":"2021-02-14 02:20:34","AP02SDTM":"2021-02-14 02:20:34","AP02EDTM":"2022-02-14 08:20:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":525,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-02-25","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1466,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.12177,"AVALU":"mg/L","BASE2":9.32837,"BASE":8.68927,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.2066,"PCHG2":-2.21474,"CHG":0.4325,"PCHG":4.97743,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-06 02:16:02","ADY":363,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-5-id-179","SUBJID":"id-179","SITEID":"USA-5","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-5","INVNAM":"Dr. USA-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":4.67743,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-08 02:16:02","TRTEDTM":"2022-02-14 08:20:34","TRT01SDTM":"2020-09-08 02:16:02","TRT01EDTM":"2021-02-14 02:20:34","TRT02SDTM":"2021-02-14 02:20:34","TRT02EDTM":"2022-02-14 08:20:34","AP01SDTM":"2020-09-08 02:16:02","AP01EDTM":"2021-02-14 02:20:34","AP02SDTM":"2021-02-14 02:20:34","AP02EDTM":"2022-02-14 08:20:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":525,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-02-25","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8209,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.87055,"AVALU":"mg/L","BASE2":9.32837,"BASE":8.68927,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.45782,"PCHG2":-15.62786,"CHG":-0.81872,"PCHG":-9.42222,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2021-12-01 02:16:02","ADY":449,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-5-id-179","SUBJID":"id-179","SITEID":"USA-5","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-5","INVNAM":"Dr. USA-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":4.67743,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-08 02:16:02","TRTEDTM":"2022-02-14 08:20:34","TRT01SDTM":"2020-09-08 02:16:02","TRT01EDTM":"2021-02-14 02:20:34","TRT02SDTM":"2021-02-14 02:20:34","TRT02EDTM":"2022-02-14 08:20:34","AP01SDTM":"2020-09-08 02:16:02","AP01EDTM":"2021-02-14 02:20:34","AP02SDTM":"2021-02-14 02:20:34","AP02EDTM":"2022-02-14 08:20:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":525,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-02-25","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5093,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.07154,"AVALU":"mg/L","BASE2":9.32837,"BASE":8.68927,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.25683,"PCHG2":-2.75326,"CHG":0.38227,"PCHG":4.3993,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-10 02:16:02","ADY":458,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-5-id-179","SUBJID":"id-179","SITEID":"USA-5","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-5","INVNAM":"Dr. USA-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":4.67743,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-08 02:16:02","TRTEDTM":"2022-02-14 08:20:34","TRT01SDTM":"2020-09-08 02:16:02","TRT01EDTM":"2021-02-14 02:20:34","TRT02SDTM":"2021-02-14 02:20:34","TRT02EDTM":"2022-02-14 08:20:34","AP01SDTM":"2020-09-08 02:16:02","AP01EDTM":"2021-02-14 02:20:34","AP02SDTM":"2021-02-14 02:20:34","AP02EDTM":"2022-02-14 08:20:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":525,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-02-25","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7704,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89394,"AVALU":"g/L","BASE2":2.89394,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-01-29 02:16:02","ADY":143,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-5-id-179","SUBJID":"id-179","SITEID":"USA-5","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-5","INVNAM":"Dr. USA-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":4.67743,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-08 02:16:02","TRTEDTM":"2022-02-14 08:20:34","TRT01SDTM":"2020-09-08 02:16:02","TRT01EDTM":"2021-02-14 02:20:34","TRT02SDTM":"2021-02-14 02:20:34","TRT02EDTM":"2022-02-14 08:20:34","AP01SDTM":"2020-09-08 02:16:02","AP01EDTM":"2021-02-14 02:20:34","AP02SDTM":"2021-02-14 02:20:34","AP02EDTM":"2022-02-14 08:20:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":525,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-02-25","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":141,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.82827,"AVALU":"g/L","BASE2":2.89394,"BASE":2.82827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.06567,"PCHG2":-2.26915,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-20 02:16:02","ADY":165,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-5-id-179","SUBJID":"id-179","SITEID":"USA-5","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-5","INVNAM":"Dr. USA-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":4.67743,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-08 02:16:02","TRTEDTM":"2022-02-14 08:20:34","TRT01SDTM":"2020-09-08 02:16:02","TRT01EDTM":"2021-02-14 02:20:34","TRT02SDTM":"2021-02-14 02:20:34","TRT02EDTM":"2022-02-14 08:20:34","AP01SDTM":"2020-09-08 02:16:02","AP01EDTM":"2021-02-14 02:20:34","AP02SDTM":"2021-02-14 02:20:34","AP02EDTM":"2022-02-14 08:20:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":525,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-02-25","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4047,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.85238,"AVALU":"g/L","BASE2":2.89394,"BASE":2.82827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04156,"PCHG2":-1.43608,"CHG":0.02411,"PCHG":0.85242,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-04-26 02:16:02","ADY":230,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-5-id-179","SUBJID":"id-179","SITEID":"USA-5","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-5","INVNAM":"Dr. USA-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":4.67743,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-08 02:16:02","TRTEDTM":"2022-02-14 08:20:34","TRT01SDTM":"2020-09-08 02:16:02","TRT01EDTM":"2021-02-14 02:20:34","TRT02SDTM":"2021-02-14 02:20:34","TRT02EDTM":"2022-02-14 08:20:34","AP01SDTM":"2020-09-08 02:16:02","AP01EDTM":"2021-02-14 02:20:34","AP02SDTM":"2021-02-14 02:20:34","AP02EDTM":"2022-02-14 08:20:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":525,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-02-25","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6795,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.92983,"AVALU":"g/L","BASE2":2.89394,"BASE":2.82827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03589,"PCHG2":1.24002,"CHG":0.10155,"PCHG":3.59065,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-05-15 02:16:02","ADY":249,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-5-id-179","SUBJID":"id-179","SITEID":"USA-5","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-5","INVNAM":"Dr. USA-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":4.67743,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-08 02:16:02","TRTEDTM":"2022-02-14 08:20:34","TRT01SDTM":"2020-09-08 02:16:02","TRT01EDTM":"2021-02-14 02:20:34","TRT02SDTM":"2021-02-14 02:20:34","TRT02EDTM":"2022-02-14 08:20:34","AP01SDTM":"2020-09-08 02:16:02","AP01EDTM":"2021-02-14 02:20:34","AP02SDTM":"2021-02-14 02:20:34","AP02EDTM":"2022-02-14 08:20:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":525,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-02-25","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1637,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9204,"AVALU":"g/L","BASE2":2.89394,"BASE":2.82827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.02646,"PCHG2":0.9143,"CHG":0.09213,"PCHG":3.25737,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-09-06 02:16:02","ADY":363,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-5-id-179","SUBJID":"id-179","SITEID":"USA-5","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-5","INVNAM":"Dr. USA-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":4.67743,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-08 02:16:02","TRTEDTM":"2022-02-14 08:20:34","TRT01SDTM":"2020-09-08 02:16:02","TRT01EDTM":"2021-02-14 02:20:34","TRT02SDTM":"2021-02-14 02:20:34","TRT02EDTM":"2022-02-14 08:20:34","AP01SDTM":"2020-09-08 02:16:02","AP01EDTM":"2021-02-14 02:20:34","AP02SDTM":"2021-02-14 02:20:34","AP02EDTM":"2022-02-14 08:20:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":525,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-02-25","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7091,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9383,"AVALU":"g/L","BASE2":2.89394,"BASE":2.82827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.04436,"PCHG2":1.53286,"CHG":0.11003,"PCHG":3.89029,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-01 02:16:02","ADY":449,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-5-id-179","SUBJID":"id-179","SITEID":"USA-5","AGE":30,"AGEU":"YEARS","SEX":"M","RACE":"BLACK OR AFRICAN AMERICAN","ETHNIC":"HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-5","INVNAM":"Dr. USA-5 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"C","STRATA2":"S1","BMRKR1":4.67743,"BMRKR2":"LOW","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-09-07","TRTSDTM":"2020-09-08 02:16:02","TRTEDTM":"2022-02-14 08:20:34","TRT01SDTM":"2020-09-08 02:16:02","TRT01EDTM":"2021-02-14 02:20:34","TRT02SDTM":"2021-02-14 02:20:34","TRT02EDTM":"2022-02-14 08:20:34","AP01SDTM":"2020-09-08 02:16:02","AP01EDTM":"2021-02-14 02:20:34","AP02SDTM":"2021-02-14 02:20:34","AP02EDTM":"2022-02-14 08:20:34","EOSSTT":"DISCONTINUED","EOTSTT":"DISCONTINUED","EOSDT":"2022-02-14","EOSDY":525,"DCSREAS":"PHYSICIAN DECISION","LSTALVDT":"2022-02-25","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6073,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.80818,"AVALU":"g/L","BASE2":2.89394,"BASE":2.82827,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08576,"PCHG2":-2.96337,"CHG":-0.02009,"PCHG":-0.71034,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-10 02:16:02","ADY":458,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-6-id-151","SUBJID":"id-151","SITEID":"USA-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-6","INVNAM":"Dr. USA-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":2.04531,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-11 21:05:28","TRTEDTM":"2023-04-12 15:05:28","TRT01SDTM":"2020-04-11 21:05:28","TRT01EDTM":"2022-04-12 09:05:28","TRT02SDTM":"2022-04-12 09:05:28","TRT02EDTM":"2023-04-12 15:05:28","AP01SDTM":"2020-04-11 21:05:28","AP01EDTM":"2022-04-12 09:05:28","AP02SDTM":"2022-04-12 09:05:28","AP02EDTM":"2023-04-12 15:05:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-12","EOSDY":1096,"LSTALVDT":"2023-04-26","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":976,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":17.94656,"AVALU":"U/L","BASE2":17.94656,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-28 21:05:28","ADY":17,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-6-id-151","SUBJID":"id-151","SITEID":"USA-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-6","INVNAM":"Dr. USA-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":2.04531,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-11 21:05:28","TRTEDTM":"2023-04-12 15:05:28","TRT01SDTM":"2020-04-11 21:05:28","TRT01EDTM":"2022-04-12 09:05:28","TRT02SDTM":"2022-04-12 09:05:28","TRT02EDTM":"2023-04-12 15:05:28","AP01SDTM":"2020-04-11 21:05:28","AP01EDTM":"2022-04-12 09:05:28","AP02SDTM":"2022-04-12 09:05:28","AP02EDTM":"2023-04-12 15:05:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-12","EOSDY":1096,"LSTALVDT":"2023-04-26","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1769,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":33.75317,"AVALU":"U/L","BASE2":17.94656,"BASE":33.75317,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":15.80661,"PCHG2":88.07597,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-01 21:05:28","ADY":112,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-6-id-151","SUBJID":"id-151","SITEID":"USA-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-6","INVNAM":"Dr. USA-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":2.04531,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-11 21:05:28","TRTEDTM":"2023-04-12 15:05:28","TRT01SDTM":"2020-04-11 21:05:28","TRT01EDTM":"2022-04-12 09:05:28","TRT02SDTM":"2022-04-12 09:05:28","TRT02EDTM":"2023-04-12 15:05:28","AP01SDTM":"2020-04-11 21:05:28","AP01EDTM":"2022-04-12 09:05:28","AP02SDTM":"2022-04-12 09:05:28","AP02EDTM":"2023-04-12 15:05:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-12","EOSDY":1096,"LSTALVDT":"2023-04-26","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5578,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":16.74974,"AVALU":"U/L","BASE2":17.94656,"BASE":33.75317,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.19682,"PCHG2":-6.66879,"CHG":-17.00343,"PCHG":-50.37579,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-14 21:05:28","ADY":337,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-6-id-151","SUBJID":"id-151","SITEID":"USA-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-6","INVNAM":"Dr. USA-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":2.04531,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-11 21:05:28","TRTEDTM":"2023-04-12 15:05:28","TRT01SDTM":"2020-04-11 21:05:28","TRT01EDTM":"2022-04-12 09:05:28","TRT02SDTM":"2022-04-12 09:05:28","TRT02EDTM":"2023-04-12 15:05:28","AP01SDTM":"2020-04-11 21:05:28","AP01EDTM":"2022-04-12 09:05:28","AP02SDTM":"2022-04-12 09:05:28","AP02EDTM":"2023-04-12 15:05:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-12","EOSDY":1096,"LSTALVDT":"2023-04-26","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":899,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":18.98493,"AVALU":"U/L","BASE2":17.94656,"BASE":33.75317,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.03837,"PCHG2":5.78591,"CHG":-14.76823,"PCHG":-43.75363,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-14 21:05:28","ADY":459,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-6-id-151","SUBJID":"id-151","SITEID":"USA-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-6","INVNAM":"Dr. USA-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":2.04531,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-11 21:05:28","TRTEDTM":"2023-04-12 15:05:28","TRT01SDTM":"2020-04-11 21:05:28","TRT01EDTM":"2022-04-12 09:05:28","TRT02SDTM":"2022-04-12 09:05:28","TRT02EDTM":"2023-04-12 15:05:28","AP01SDTM":"2020-04-11 21:05:28","AP01EDTM":"2022-04-12 09:05:28","AP02SDTM":"2022-04-12 09:05:28","AP02EDTM":"2023-04-12 15:05:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-12","EOSDY":1096,"LSTALVDT":"2023-04-26","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2070,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":15.04877,"AVALU":"U/L","BASE2":17.94656,"BASE":33.75317,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.89779,"PCHG2":-16.14677,"CHG":-18.7044,"PCHG":-55.41524,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-17 21:05:28","ADY":766,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-6-id-151","SUBJID":"id-151","SITEID":"USA-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-6","INVNAM":"Dr. USA-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":2.04531,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-11 21:05:28","TRTEDTM":"2023-04-12 15:05:28","TRT01SDTM":"2020-04-11 21:05:28","TRT01EDTM":"2022-04-12 09:05:28","TRT02SDTM":"2022-04-12 09:05:28","TRT02EDTM":"2023-04-12 15:05:28","AP01SDTM":"2020-04-11 21:05:28","AP01EDTM":"2022-04-12 09:05:28","AP02SDTM":"2022-04-12 09:05:28","AP02EDTM":"2023-04-12 15:05:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-12","EOSDY":1096,"LSTALVDT":"2023-04-26","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3093,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":4.51607,"AVALU":"U/L","BASE2":17.94656,"BASE":33.75317,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.43049,"PCHG2":-74.83601,"CHG":-29.2371,"PCHG":-86.62031,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-2","BTOXGR":"0","ADTM":"2022-11-02 21:05:28","ADY":935,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-6-id-151","SUBJID":"id-151","SITEID":"USA-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-6","INVNAM":"Dr. USA-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":2.04531,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-11 21:05:28","TRTEDTM":"2023-04-12 15:05:28","TRT01SDTM":"2020-04-11 21:05:28","TRT01EDTM":"2022-04-12 09:05:28","TRT02SDTM":"2022-04-12 09:05:28","TRT02EDTM":"2023-04-12 15:05:28","AP01SDTM":"2020-04-11 21:05:28","AP01EDTM":"2022-04-12 09:05:28","AP02SDTM":"2022-04-12 09:05:28","AP02EDTM":"2023-04-12 15:05:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-12","EOSDY":1096,"LSTALVDT":"2023-04-26","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1911,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":3.31163,"AVALU":"U/L","BASE2":17.94656,"BASE":33.75317,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-14.63493,"PCHG2":-81.54728,"CHG":-30.44154,"PCHG":-90.18869,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2022-11-24 21:05:28","ADY":957,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-6-id-151","SUBJID":"id-151","SITEID":"USA-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-6","INVNAM":"Dr. USA-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":2.04531,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-11 21:05:28","TRTEDTM":"2023-04-12 15:05:28","TRT01SDTM":"2020-04-11 21:05:28","TRT01EDTM":"2022-04-12 09:05:28","TRT02SDTM":"2022-04-12 09:05:28","TRT02EDTM":"2023-04-12 15:05:28","AP01SDTM":"2020-04-11 21:05:28","AP01EDTM":"2022-04-12 09:05:28","AP02SDTM":"2022-04-12 09:05:28","AP02EDTM":"2023-04-12 15:05:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-12","EOSDY":1096,"LSTALVDT":"2023-04-26","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3761,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.4966,"AVALU":"mg/L","BASE2":8.4966,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-04-28 21:05:28","ADY":17,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-6-id-151","SUBJID":"id-151","SITEID":"USA-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-6","INVNAM":"Dr. USA-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":2.04531,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-11 21:05:28","TRTEDTM":"2023-04-12 15:05:28","TRT01SDTM":"2020-04-11 21:05:28","TRT01EDTM":"2022-04-12 09:05:28","TRT02SDTM":"2022-04-12 09:05:28","TRT02EDTM":"2023-04-12 15:05:28","AP01SDTM":"2020-04-11 21:05:28","AP01EDTM":"2022-04-12 09:05:28","AP02SDTM":"2022-04-12 09:05:28","AP02EDTM":"2023-04-12 15:05:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-12","EOSDY":1096,"LSTALVDT":"2023-04-26","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4066,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.62237,"AVALU":"mg/L","BASE2":8.4966,"BASE":9.62237,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":1.12577,"PCHG2":13.24968,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-01 21:05:28","ADY":112,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-6-id-151","SUBJID":"id-151","SITEID":"USA-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-6","INVNAM":"Dr. USA-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":2.04531,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-11 21:05:28","TRTEDTM":"2023-04-12 15:05:28","TRT01SDTM":"2020-04-11 21:05:28","TRT01EDTM":"2022-04-12 09:05:28","TRT02SDTM":"2022-04-12 09:05:28","TRT02EDTM":"2023-04-12 15:05:28","AP01SDTM":"2020-04-11 21:05:28","AP01EDTM":"2022-04-12 09:05:28","AP02SDTM":"2022-04-12 09:05:28","AP02EDTM":"2023-04-12 15:05:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-12","EOSDY":1096,"LSTALVDT":"2023-04-26","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4074,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.8955,"AVALU":"mg/L","BASE2":8.4966,"BASE":9.62237,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.60111,"PCHG2":-7.07467,"CHG":-1.72688,"PCHG":-17.94649,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-03-14 21:05:28","ADY":337,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-6-id-151","SUBJID":"id-151","SITEID":"USA-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-6","INVNAM":"Dr. USA-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":2.04531,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-11 21:05:28","TRTEDTM":"2023-04-12 15:05:28","TRT01SDTM":"2020-04-11 21:05:28","TRT01EDTM":"2022-04-12 09:05:28","TRT02SDTM":"2022-04-12 09:05:28","TRT02EDTM":"2023-04-12 15:05:28","AP01SDTM":"2020-04-11 21:05:28","AP01EDTM":"2022-04-12 09:05:28","AP02SDTM":"2022-04-12 09:05:28","AP02EDTM":"2023-04-12 15:05:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-12","EOSDY":1096,"LSTALVDT":"2023-04-26","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8204,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.73423,"AVALU":"mg/L","BASE2":8.4966,"BASE":9.62237,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.23763,"PCHG2":14.56613,"CHG":0.11185,"PCHG":1.16243,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-14 21:05:28","ADY":459,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-6-id-151","SUBJID":"id-151","SITEID":"USA-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-6","INVNAM":"Dr. USA-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":2.04531,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-11 21:05:28","TRTEDTM":"2023-04-12 15:05:28","TRT01SDTM":"2020-04-11 21:05:28","TRT01EDTM":"2022-04-12 09:05:28","TRT02SDTM":"2022-04-12 09:05:28","TRT02EDTM":"2023-04-12 15:05:28","AP01SDTM":"2020-04-11 21:05:28","AP01EDTM":"2022-04-12 09:05:28","AP02SDTM":"2022-04-12 09:05:28","AP02EDTM":"2023-04-12 15:05:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-12","EOSDY":1096,"LSTALVDT":"2023-04-26","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":321,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.41025,"AVALU":"mg/L","BASE2":8.4966,"BASE":9.62237,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.08635,"PCHG2":-1.01633,"CHG":-1.21213,"PCHG":-12.59695,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-17 21:05:28","ADY":766,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-6-id-151","SUBJID":"id-151","SITEID":"USA-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-6","INVNAM":"Dr. USA-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":2.04531,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-11 21:05:28","TRTEDTM":"2023-04-12 15:05:28","TRT01SDTM":"2020-04-11 21:05:28","TRT01EDTM":"2022-04-12 09:05:28","TRT02SDTM":"2022-04-12 09:05:28","TRT02EDTM":"2023-04-12 15:05:28","AP01SDTM":"2020-04-11 21:05:28","AP01EDTM":"2022-04-12 09:05:28","AP02SDTM":"2022-04-12 09:05:28","AP02EDTM":"2023-04-12 15:05:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-12","EOSDY":1096,"LSTALVDT":"2023-04-26","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":7338,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.69332,"AVALU":"mg/L","BASE2":8.4966,"BASE":9.62237,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.19672,"PCHG2":2.31527,"CHG":-0.92905,"PCHG":-9.65513,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-02 21:05:28","ADY":935,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-6-id-151","SUBJID":"id-151","SITEID":"USA-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-6","INVNAM":"Dr. USA-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":2.04531,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-11 21:05:28","TRTEDTM":"2023-04-12 15:05:28","TRT01SDTM":"2020-04-11 21:05:28","TRT01EDTM":"2022-04-12 09:05:28","TRT02SDTM":"2022-04-12 09:05:28","TRT02EDTM":"2023-04-12 15:05:28","AP01SDTM":"2020-04-11 21:05:28","AP01EDTM":"2022-04-12 09:05:28","AP02SDTM":"2022-04-12 09:05:28","AP02EDTM":"2023-04-12 15:05:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-12","EOSDY":1096,"LSTALVDT":"2023-04-26","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2459,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.24432,"AVALU":"mg/L","BASE2":8.4966,"BASE":9.62237,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.25228,"PCHG2":-2.96921,"CHG":-1.37805,"PCHG":-14.32136,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-24 21:05:28","ADY":957,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-6-id-151","SUBJID":"id-151","SITEID":"USA-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-6","INVNAM":"Dr. USA-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":2.04531,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-11 21:05:28","TRTEDTM":"2023-04-12 15:05:28","TRT01SDTM":"2020-04-11 21:05:28","TRT01EDTM":"2022-04-12 09:05:28","TRT02SDTM":"2022-04-12 09:05:28","TRT02EDTM":"2023-04-12 15:05:28","AP01SDTM":"2020-04-11 21:05:28","AP01EDTM":"2022-04-12 09:05:28","AP02SDTM":"2022-04-12 09:05:28","AP02EDTM":"2023-04-12 15:05:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-12","EOSDY":1096,"LSTALVDT":"2023-04-26","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5297,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.1055,"AVALU":"g/L","BASE2":3.1055,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"HIGH","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"2","BTOXGR":"0","ADTM":"2020-04-28 21:05:28","ADY":17,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"","ATOXGRH":"2","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-6-id-151","SUBJID":"id-151","SITEID":"USA-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-6","INVNAM":"Dr. USA-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":2.04531,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-11 21:05:28","TRTEDTM":"2023-04-12 15:05:28","TRT01SDTM":"2020-04-11 21:05:28","TRT01EDTM":"2022-04-12 09:05:28","TRT02SDTM":"2022-04-12 09:05:28","TRT02EDTM":"2023-04-12 15:05:28","AP01SDTM":"2020-04-11 21:05:28","AP01EDTM":"2022-04-12 09:05:28","AP02SDTM":"2022-04-12 09:05:28","AP02EDTM":"2023-04-12 15:05:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-12","EOSDY":1096,"LSTALVDT":"2023-04-26","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4337,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.72075,"AVALU":"g/L","BASE2":3.1055,"BASE":2.72075,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.38475,"PCHG2":-12.38932,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-01 21:05:28","ADY":112,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-6-id-151","SUBJID":"id-151","SITEID":"USA-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-6","INVNAM":"Dr. USA-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":2.04531,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-11 21:05:28","TRTEDTM":"2023-04-12 15:05:28","TRT01SDTM":"2020-04-11 21:05:28","TRT01EDTM":"2022-04-12 09:05:28","TRT02SDTM":"2022-04-12 09:05:28","TRT02EDTM":"2023-04-12 15:05:28","AP01SDTM":"2020-04-11 21:05:28","AP01EDTM":"2022-04-12 09:05:28","AP02SDTM":"2022-04-12 09:05:28","AP02EDTM":"2023-04-12 15:05:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-12","EOSDY":1096,"LSTALVDT":"2023-04-26","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7312,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.79087,"AVALU":"g/L","BASE2":3.1055,"BASE":2.72075,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.31463,"PCHG2":-10.13127,"CHG":0.07012,"PCHG":2.57736,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-14 21:05:28","ADY":337,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-6-id-151","SUBJID":"id-151","SITEID":"USA-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-6","INVNAM":"Dr. USA-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":2.04531,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-11 21:05:28","TRTEDTM":"2023-04-12 15:05:28","TRT01SDTM":"2020-04-11 21:05:28","TRT01EDTM":"2022-04-12 09:05:28","TRT02SDTM":"2022-04-12 09:05:28","TRT02EDTM":"2023-04-12 15:05:28","AP01SDTM":"2020-04-11 21:05:28","AP01EDTM":"2022-04-12 09:05:28","AP02SDTM":"2022-04-12 09:05:28","AP02EDTM":"2023-04-12 15:05:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-12","EOSDY":1096,"LSTALVDT":"2023-04-26","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6373,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.71534,"AVALU":"g/L","BASE2":3.1055,"BASE":2.72075,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.39016,"PCHG2":-12.56367,"CHG":-0.00541,"PCHG":-0.199,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-14 21:05:28","ADY":459,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-6-id-151","SUBJID":"id-151","SITEID":"USA-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-6","INVNAM":"Dr. USA-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":2.04531,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-11 21:05:28","TRTEDTM":"2023-04-12 15:05:28","TRT01SDTM":"2020-04-11 21:05:28","TRT01EDTM":"2022-04-12 09:05:28","TRT02SDTM":"2022-04-12 09:05:28","TRT02EDTM":"2023-04-12 15:05:28","AP01SDTM":"2020-04-11 21:05:28","AP01EDTM":"2022-04-12 09:05:28","AP02SDTM":"2022-04-12 09:05:28","AP02EDTM":"2023-04-12 15:05:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-12","EOSDY":1096,"LSTALVDT":"2023-04-26","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6651,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.89029,"AVALU":"g/L","BASE2":3.1055,"BASE":2.72075,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21521,"PCHG2":-6.92986,"CHG":0.16954,"PCHG":6.23149,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-05-17 21:05:28","ADY":766,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-6-id-151","SUBJID":"id-151","SITEID":"USA-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-6","INVNAM":"Dr. USA-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":2.04531,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-11 21:05:28","TRTEDTM":"2023-04-12 15:05:28","TRT01SDTM":"2020-04-11 21:05:28","TRT01EDTM":"2022-04-12 09:05:28","TRT02SDTM":"2022-04-12 09:05:28","TRT02EDTM":"2023-04-12 15:05:28","AP01SDTM":"2020-04-11 21:05:28","AP01EDTM":"2022-04-12 09:05:28","AP02SDTM":"2022-04-12 09:05:28","AP02EDTM":"2023-04-12 15:05:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-12","EOSDY":1096,"LSTALVDT":"2023-04-26","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":1483,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.96071,"AVALU":"g/L","BASE2":3.1055,"BASE":2.72075,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.14479,"PCHG2":-4.66243,"CHG":0.23996,"PCHG":8.81957,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-02 21:05:28","ADY":935,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-6-id-151","SUBJID":"id-151","SITEID":"USA-6","AGE":30,"AGEU":"YEARS","SEX":"F","RACE":"WHITE","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-6","INVNAM":"Dr. USA-6 Doe","ARM":"B: Placebo","ARMCD":"ARM B","ACTARM":"B: Placebo","ACTARMCD":"ARM B","TRT01P":"B: Placebo","TRT01A":"B: Placebo","TRT02P":"B: Placebo","TRT02A":"B: Placebo","REGION1":"North America","STRATA1":"C","STRATA2":"S2","BMRKR1":2.04531,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-04-07","TRTSDTM":"2020-04-11 21:05:28","TRTEDTM":"2023-04-12 15:05:28","TRT01SDTM":"2020-04-11 21:05:28","TRT01EDTM":"2022-04-12 09:05:28","TRT02SDTM":"2022-04-12 09:05:28","TRT02EDTM":"2023-04-12 15:05:28","AP01SDTM":"2020-04-11 21:05:28","AP01EDTM":"2022-04-12 09:05:28","AP02SDTM":"2022-04-12 09:05:28","AP02EDTM":"2023-04-12 15:05:28","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-04-12","EOSDY":1096,"LSTALVDT":"2023-04-26","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5146,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81238,"AVALU":"g/L","BASE2":3.1055,"BASE":2.72075,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.29312,"PCHG2":-9.43875,"CHG":0.09163,"PCHG":3.36782,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2022-11-24 21:05:28","ADY":957,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-8-id-206","SUBJID":"id-206","SITEID":"USA-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-8","INVNAM":"Dr. USA-8 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":14.47806,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-22 10:23:30","TRTEDTM":"2022-07-22 04:23:30","TRT01SDTM":"2019-07-22 10:23:30","TRT01EDTM":"2021-07-21 22:23:30","TRT02SDTM":"2021-07-21 22:23:30","TRT02EDTM":"2022-07-22 04:23:30","AP01SDTM":"2019-07-22 10:23:30","AP01EDTM":"2021-07-21 22:23:30","AP02SDTM":"2021-07-21 22:23:30","AP02EDTM":"2022-07-22 04:23:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-22","EOSDY":1096,"LSTALVDT":"2022-08-07","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4222,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":24.10726,"AVALU":"U/L","BASE2":24.10726,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-09-29 10:23:30","ADY":69,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-8-id-206","SUBJID":"id-206","SITEID":"USA-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-8","INVNAM":"Dr. USA-8 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":14.47806,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-22 10:23:30","TRTEDTM":"2022-07-22 04:23:30","TRT01SDTM":"2019-07-22 10:23:30","TRT01EDTM":"2021-07-21 22:23:30","TRT02SDTM":"2021-07-21 22:23:30","TRT02EDTM":"2022-07-22 04:23:30","AP01SDTM":"2019-07-22 10:23:30","AP01EDTM":"2021-07-21 22:23:30","AP02SDTM":"2021-07-21 22:23:30","AP02EDTM":"2022-07-22 04:23:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-22","EOSDY":1096,"LSTALVDT":"2022-08-07","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3907,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":34.99971,"AVALU":"U/L","BASE2":24.10726,"BASE":34.99971,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":10.89244,"PCHG2":45.18324,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2019-11-21 10:23:30","ADY":122,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-8-id-206","SUBJID":"id-206","SITEID":"USA-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-8","INVNAM":"Dr. USA-8 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":14.47806,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-22 10:23:30","TRTEDTM":"2022-07-22 04:23:30","TRT01SDTM":"2019-07-22 10:23:30","TRT01EDTM":"2021-07-21 22:23:30","TRT02SDTM":"2021-07-21 22:23:30","TRT02EDTM":"2022-07-22 04:23:30","AP01SDTM":"2019-07-22 10:23:30","AP01EDTM":"2021-07-21 22:23:30","AP02SDTM":"2021-07-21 22:23:30","AP02EDTM":"2022-07-22 04:23:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-22","EOSDY":1096,"LSTALVDT":"2022-08-07","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2981,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":2.54561,"AVALU":"U/L","BASE2":24.10726,"BASE":34.99971,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-21.56166,"PCHG2":-89.44051,"CHG":-32.4541,"PCHG":-92.72678,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2020-01-30 10:23:30","ADY":192,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-8-id-206","SUBJID":"id-206","SITEID":"USA-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-8","INVNAM":"Dr. USA-8 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":14.47806,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-22 10:23:30","TRTEDTM":"2022-07-22 04:23:30","TRT01SDTM":"2019-07-22 10:23:30","TRT01EDTM":"2021-07-21 22:23:30","TRT02SDTM":"2021-07-21 22:23:30","TRT02EDTM":"2022-07-22 04:23:30","AP01SDTM":"2019-07-22 10:23:30","AP01EDTM":"2021-07-21 22:23:30","AP02SDTM":"2021-07-21 22:23:30","AP02EDTM":"2022-07-22 04:23:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-22","EOSDY":1096,"LSTALVDT":"2022-08-07","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1928,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":26.706,"AVALU":"U/L","BASE2":24.10726,"BASE":34.99971,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":2.59873,"PCHG2":10.77987,"CHG":-8.29371,"PCHG":-23.69652,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-02-26 10:23:30","ADY":219,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-8-id-206","SUBJID":"id-206","SITEID":"USA-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-8","INVNAM":"Dr. USA-8 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":14.47806,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-22 10:23:30","TRTEDTM":"2022-07-22 04:23:30","TRT01SDTM":"2019-07-22 10:23:30","TRT01EDTM":"2021-07-21 22:23:30","TRT02SDTM":"2021-07-21 22:23:30","TRT02EDTM":"2022-07-22 04:23:30","AP01SDTM":"2019-07-22 10:23:30","AP01EDTM":"2021-07-21 22:23:30","AP02SDTM":"2021-07-21 22:23:30","AP02EDTM":"2022-07-22 04:23:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-22","EOSDY":1096,"LSTALVDT":"2022-08-07","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":886,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":10.15406,"AVALU":"U/L","BASE2":24.10726,"BASE":34.99971,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-13.9532,"PCHG2":-57.87966,"CHG":-24.84565,"PCHG":-70.98815,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-09-24 10:23:30","ADY":430,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-8-id-206","SUBJID":"id-206","SITEID":"USA-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-8","INVNAM":"Dr. USA-8 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":14.47806,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-22 10:23:30","TRTEDTM":"2022-07-22 04:23:30","TRT01SDTM":"2019-07-22 10:23:30","TRT01EDTM":"2021-07-21 22:23:30","TRT02SDTM":"2021-07-21 22:23:30","TRT02EDTM":"2022-07-22 04:23:30","AP01SDTM":"2019-07-22 10:23:30","AP01EDTM":"2021-07-21 22:23:30","AP02SDTM":"2021-07-21 22:23:30","AP02EDTM":"2022-07-22 04:23:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-22","EOSDY":1096,"LSTALVDT":"2022-08-07","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":2527,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":25.11668,"AVALU":"U/L","BASE2":24.10726,"BASE":34.99971,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":1.00942,"PCHG2":4.1872,"CHG":-9.88302,"PCHG":-28.23744,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-07-29 10:23:30","ADY":738,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-8-id-206","SUBJID":"id-206","SITEID":"USA-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-8","INVNAM":"Dr. USA-8 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":14.47806,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-22 10:23:30","TRTEDTM":"2022-07-22 04:23:30","TRT01SDTM":"2019-07-22 10:23:30","TRT01EDTM":"2021-07-21 22:23:30","TRT02SDTM":"2021-07-21 22:23:30","TRT02EDTM":"2022-07-22 04:23:30","AP01SDTM":"2019-07-22 10:23:30","AP01EDTM":"2021-07-21 22:23:30","AP02SDTM":"2021-07-21 22:23:30","AP02EDTM":"2022-07-22 04:23:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-22","EOSDY":1096,"LSTALVDT":"2022-08-07","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":7262,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":5.21643,"AVALU":"U/L","BASE2":24.10726,"BASE":34.99971,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-18.89084,"PCHG2":-78.3616,"CHG":-29.78328,"PCHG":-85.0958,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-4","BTOXGR":"0","ADTM":"2021-10-29 10:23:30","ADY":830,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-8-id-206","SUBJID":"id-206","SITEID":"USA-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-8","INVNAM":"Dr. USA-8 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":14.47806,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-22 10:23:30","TRTEDTM":"2022-07-22 04:23:30","TRT01SDTM":"2019-07-22 10:23:30","TRT01EDTM":"2021-07-21 22:23:30","TRT02SDTM":"2021-07-21 22:23:30","TRT02EDTM":"2022-07-22 04:23:30","AP01SDTM":"2019-07-22 10:23:30","AP01EDTM":"2021-07-21 22:23:30","AP02SDTM":"2021-07-21 22:23:30","AP02EDTM":"2022-07-22 04:23:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-22","EOSDY":1096,"LSTALVDT":"2022-08-07","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":657,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.39165,"AVALU":"mg/L","BASE2":9.39165,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"1","ADTM":"2019-09-29 10:23:30","ADY":69,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-8-id-206","SUBJID":"id-206","SITEID":"USA-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-8","INVNAM":"Dr. USA-8 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":14.47806,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-22 10:23:30","TRTEDTM":"2022-07-22 04:23:30","TRT01SDTM":"2019-07-22 10:23:30","TRT01EDTM":"2021-07-21 22:23:30","TRT02SDTM":"2021-07-21 22:23:30","TRT02EDTM":"2022-07-22 04:23:30","AP01SDTM":"2019-07-22 10:23:30","AP01EDTM":"2021-07-21 22:23:30","AP02SDTM":"2021-07-21 22:23:30","AP02EDTM":"2022-07-22 04:23:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-22","EOSDY":1096,"LSTALVDT":"2022-08-07","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3029,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.25492,"AVALU":"mg/L","BASE2":9.39165,"BASE":10.25492,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.86327,"PCHG2":9.19187,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"1","BTOXGR":"1","ADTM":"2019-11-21 10:23:30","ADY":122,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"1","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-8-id-206","SUBJID":"id-206","SITEID":"USA-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-8","INVNAM":"Dr. USA-8 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":14.47806,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-22 10:23:30","TRTEDTM":"2022-07-22 04:23:30","TRT01SDTM":"2019-07-22 10:23:30","TRT01EDTM":"2021-07-21 22:23:30","TRT02SDTM":"2021-07-21 22:23:30","TRT02EDTM":"2022-07-22 04:23:30","AP01SDTM":"2019-07-22 10:23:30","AP01EDTM":"2021-07-21 22:23:30","AP02SDTM":"2021-07-21 22:23:30","AP02EDTM":"2022-07-22 04:23:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-22","EOSDY":1096,"LSTALVDT":"2022-08-07","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":136,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.36513,"AVALU":"mg/L","BASE2":9.39165,"BASE":10.25492,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-2.02652,"PCHG2":-21.57793,"CHG":-2.88979,"PCHG":-28.17957,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-2","BTOXGR":"1","ADTM":"2020-01-30 10:23:30","ADY":192,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"2","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-8-id-206","SUBJID":"id-206","SITEID":"USA-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-8","INVNAM":"Dr. USA-8 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":14.47806,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-22 10:23:30","TRTEDTM":"2022-07-22 04:23:30","TRT01SDTM":"2019-07-22 10:23:30","TRT01EDTM":"2021-07-21 22:23:30","TRT02SDTM":"2021-07-21 22:23:30","TRT02EDTM":"2022-07-22 04:23:30","AP01SDTM":"2019-07-22 10:23:30","AP01EDTM":"2021-07-21 22:23:30","AP02SDTM":"2021-07-21 22:23:30","AP02EDTM":"2022-07-22 04:23:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-22","EOSDY":1096,"LSTALVDT":"2022-08-07","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5798,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.51225,"AVALU":"mg/L","BASE2":9.39165,"BASE":10.25492,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.8794,"PCHG2":-9.36369,"CHG":-1.74267,"PCHG":-16.99353,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2020-02-26 10:23:30","ADY":219,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-8-id-206","SUBJID":"id-206","SITEID":"USA-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-8","INVNAM":"Dr. USA-8 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":14.47806,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-22 10:23:30","TRTEDTM":"2022-07-22 04:23:30","TRT01SDTM":"2019-07-22 10:23:30","TRT01EDTM":"2021-07-21 22:23:30","TRT02SDTM":"2021-07-21 22:23:30","TRT02EDTM":"2022-07-22 04:23:30","AP01SDTM":"2019-07-22 10:23:30","AP01EDTM":"2021-07-21 22:23:30","AP02SDTM":"2021-07-21 22:23:30","AP02EDTM":"2022-07-22 04:23:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-22","EOSDY":1096,"LSTALVDT":"2022-08-07","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":4346,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.50289,"AVALU":"mg/L","BASE2":9.39165,"BASE":10.25492,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.88876,"PCHG2":-20.11105,"CHG":-2.75203,"PCHG":-26.83617,"ANRIND":"LOW","BNRIND":"HIGH","SHIFT1":"HIGH to LOW","ATOXGR":"-4","BTOXGR":"1","ADTM":"2020-09-24 10:23:30","ADY":430,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"4","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-8-id-206","SUBJID":"id-206","SITEID":"USA-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-8","INVNAM":"Dr. USA-8 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":14.47806,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-22 10:23:30","TRTEDTM":"2022-07-22 04:23:30","TRT01SDTM":"2019-07-22 10:23:30","TRT01EDTM":"2021-07-21 22:23:30","TRT02SDTM":"2021-07-21 22:23:30","TRT02EDTM":"2022-07-22 04:23:30","AP01SDTM":"2019-07-22 10:23:30","AP01EDTM":"2021-07-21 22:23:30","AP02SDTM":"2021-07-21 22:23:30","AP02EDTM":"2022-07-22 04:23:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-22","EOSDY":1096,"LSTALVDT":"2022-08-07","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1729,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":10.14482,"AVALU":"mg/L","BASE2":9.39165,"BASE":10.25492,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.75317,"PCHG2":8.01955,"CHG":-0.1101,"PCHG":-1.07364,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"HIGH to HIGH","ATOXGR":"4","BTOXGR":"1","ADTM":"2021-07-29 10:23:30","ADY":738,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"","ATOXGRH":"4","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-8-id-206","SUBJID":"id-206","SITEID":"USA-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-8","INVNAM":"Dr. USA-8 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":14.47806,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-22 10:23:30","TRTEDTM":"2022-07-22 04:23:30","TRT01SDTM":"2019-07-22 10:23:30","TRT01EDTM":"2021-07-21 22:23:30","TRT02SDTM":"2021-07-21 22:23:30","TRT02EDTM":"2022-07-22 04:23:30","AP01SDTM":"2019-07-22 10:23:30","AP01EDTM":"2021-07-21 22:23:30","AP02SDTM":"2021-07-21 22:23:30","AP02EDTM":"2022-07-22 04:23:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-22","EOSDY":1096,"LSTALVDT":"2022-08-07","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":8386,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.61333,"AVALU":"mg/L","BASE2":9.39165,"BASE":10.25492,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.77832,"PCHG2":-8.28739,"CHG":-1.64159,"PCHG":-16.00784,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"1","ADTM":"2021-10-29 10:23:30","ADY":830,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"","BTOXGRH":"1","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-8-id-206","SUBJID":"id-206","SITEID":"USA-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-8","INVNAM":"Dr. USA-8 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":14.47806,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-22 10:23:30","TRTEDTM":"2022-07-22 04:23:30","TRT01SDTM":"2019-07-22 10:23:30","TRT01EDTM":"2021-07-21 22:23:30","TRT02SDTM":"2021-07-21 22:23:30","TRT02EDTM":"2022-07-22 04:23:30","AP01SDTM":"2019-07-22 10:23:30","AP01EDTM":"2021-07-21 22:23:30","AP02SDTM":"2021-07-21 22:23:30","AP02EDTM":"2022-07-22 04:23:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-22","EOSDY":1096,"LSTALVDT":"2022-08-07","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2828,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.95581,"AVALU":"g/L","BASE2":2.95581,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"0","BTOXGR":"3","ADTM":"2019-09-29 10:23:30","ADY":69,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-8-id-206","SUBJID":"id-206","SITEID":"USA-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-8","INVNAM":"Dr. USA-8 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":14.47806,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-22 10:23:30","TRTEDTM":"2022-07-22 04:23:30","TRT01SDTM":"2019-07-22 10:23:30","TRT01EDTM":"2021-07-21 22:23:30","TRT02SDTM":"2021-07-21 22:23:30","TRT02EDTM":"2022-07-22 04:23:30","AP01SDTM":"2019-07-22 10:23:30","AP01EDTM":"2021-07-21 22:23:30","AP02SDTM":"2021-07-21 22:23:30","AP02EDTM":"2022-07-22 04:23:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-22","EOSDY":1096,"LSTALVDT":"2022-08-07","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":8179,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":3.07695,"AVALU":"g/L","BASE2":2.95581,"BASE":3.07695,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.12113,"PCHG2":4.09819,"CHG":0,"PCHG":0,"ANRIND":"HIGH","BNRIND":"HIGH","SHIFT1":"","ATOXGR":"3","BTOXGR":"3","ADTM":"2019-11-21 10:23:30","ADY":122,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"Y","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"","ATOXGRH":"3","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-8-id-206","SUBJID":"id-206","SITEID":"USA-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-8","INVNAM":"Dr. USA-8 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":14.47806,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-22 10:23:30","TRTEDTM":"2022-07-22 04:23:30","TRT01SDTM":"2019-07-22 10:23:30","TRT01EDTM":"2021-07-21 22:23:30","TRT02SDTM":"2021-07-21 22:23:30","TRT02EDTM":"2022-07-22 04:23:30","AP01SDTM":"2019-07-22 10:23:30","AP01EDTM":"2021-07-21 22:23:30","AP02SDTM":"2021-07-21 22:23:30","AP02EDTM":"2022-07-22 04:23:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-22","EOSDY":1096,"LSTALVDT":"2022-08-07","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2272,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.75846,"AVALU":"g/L","BASE2":2.95581,"BASE":3.07695,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.19735,"PCHG2":-6.67682,"CHG":-0.31849,"PCHG":-10.35082,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-01-30 10:23:30","ADY":192,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-8-id-206","SUBJID":"id-206","SITEID":"USA-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-8","INVNAM":"Dr. USA-8 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":14.47806,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-22 10:23:30","TRTEDTM":"2022-07-22 04:23:30","TRT01SDTM":"2019-07-22 10:23:30","TRT01EDTM":"2021-07-21 22:23:30","TRT02SDTM":"2021-07-21 22:23:30","TRT02EDTM":"2022-07-22 04:23:30","AP01SDTM":"2019-07-22 10:23:30","AP01EDTM":"2021-07-21 22:23:30","AP02SDTM":"2021-07-21 22:23:30","AP02EDTM":"2022-07-22 04:23:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-22","EOSDY":1096,"LSTALVDT":"2022-08-07","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7143,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.73959,"AVALU":"g/L","BASE2":2.95581,"BASE":3.07695,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.21623,"PCHG2":-7.31536,"CHG":-0.33736,"PCHG":-10.96422,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-02-26 10:23:30","ADY":219,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-8-id-206","SUBJID":"id-206","SITEID":"USA-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-8","INVNAM":"Dr. USA-8 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":14.47806,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-22 10:23:30","TRTEDTM":"2022-07-22 04:23:30","TRT01SDTM":"2019-07-22 10:23:30","TRT01EDTM":"2021-07-21 22:23:30","TRT02SDTM":"2021-07-21 22:23:30","TRT02EDTM":"2022-07-22 04:23:30","AP01SDTM":"2019-07-22 10:23:30","AP01EDTM":"2021-07-21 22:23:30","AP02SDTM":"2021-07-21 22:23:30","AP02EDTM":"2022-07-22 04:23:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-22","EOSDY":1096,"LSTALVDT":"2022-08-07","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4733,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.94632,"AVALU":"g/L","BASE2":2.95581,"BASE":3.07695,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.00949,"PCHG2":-0.3211,"CHG":-0.13063,"PCHG":-4.24531,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2020-09-24 10:23:30","ADY":430,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-8-id-206","SUBJID":"id-206","SITEID":"USA-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-8","INVNAM":"Dr. USA-8 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":14.47806,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-22 10:23:30","TRTEDTM":"2022-07-22 04:23:30","TRT01SDTM":"2019-07-22 10:23:30","TRT01EDTM":"2021-07-21 22:23:30","TRT02SDTM":"2021-07-21 22:23:30","TRT02EDTM":"2022-07-22 04:23:30","AP01SDTM":"2019-07-22 10:23:30","AP01EDTM":"2021-07-21 22:23:30","AP02SDTM":"2021-07-21 22:23:30","AP02EDTM":"2022-07-22 04:23:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-22","EOSDY":1096,"LSTALVDT":"2022-08-07","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2104,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.966,"AVALU":"g/L","BASE2":2.95581,"BASE":3.07695,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.01019,"PCHG2":0.34467,"CHG":-0.11095,"PCHG":-3.60575,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-07-29 10:23:30","ADY":738,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-8-id-206","SUBJID":"id-206","SITEID":"USA-8","AGE":34,"AGEU":"YEARS","SEX":"F","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-8","INVNAM":"Dr. USA-8 Doe","ARM":"C: Combination","ARMCD":"ARM C","ACTARM":"C: Combination","ACTARMCD":"ARM C","TRT01P":"C: Combination","TRT01A":"C: Combination","TRT02P":"B: Placebo","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"B","STRATA2":"S1","BMRKR1":14.47806,"BMRKR2":"HIGH","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"Y","BEP01FL":"Y","AEWITHFL":"N","RANDDT":"2019-07-19","TRTSDTM":"2019-07-22 10:23:30","TRTEDTM":"2022-07-22 04:23:30","TRT01SDTM":"2019-07-22 10:23:30","TRT01EDTM":"2021-07-21 22:23:30","TRT02SDTM":"2021-07-21 22:23:30","TRT02EDTM":"2022-07-22 04:23:30","AP01SDTM":"2019-07-22 10:23:30","AP01EDTM":"2021-07-21 22:23:30","AP02SDTM":"2021-07-21 22:23:30","AP02EDTM":"2022-07-22 04:23:30","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2022-07-22","EOSDY":1096,"LSTALVDT":"2022-08-07","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6942,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.7104,"AVALU":"g/L","BASE2":2.95581,"BASE":3.07695,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.24542,"PCHG2":-8.30289,"CHG":-0.36655,"PCHG":-11.91287,"ANRIND":"NORMAL","BNRIND":"HIGH","SHIFT1":"HIGH to NORMAL","ATOXGR":"0","BTOXGR":"3","ADTM":"2021-10-29 10:23:30","ADY":830,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"","BTOXGRH":"3","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-9-id-130","SUBJID":"id-130","SITEID":"USA-9","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-9","INVNAM":"Dr. USA-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":1.28053,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-18 19:43:32","TRTEDTM":"2023-07-19 13:43:32","TRT01SDTM":"2020-07-18 19:43:32","TRT01EDTM":"2022-07-19 07:43:32","TRT02SDTM":"2022-07-19 07:43:32","TRT02EDTM":"2023-07-19 13:43:32","AP01SDTM":"2020-07-18 19:43:32","AP01EDTM":"2022-07-19 07:43:32","AP02SDTM":"2022-07-19 07:43:32","AP02EDTM":"2023-07-19 13:43:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-19","EOSDY":1096,"LSTALVDT":"2023-08-09","ASEQ":1,"LBSEQ":1,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3463,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.92471,"AVALU":"U/L","BASE2":13.92471,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-09 19:43:32","ADY":22,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-9-id-130","SUBJID":"id-130","SITEID":"USA-9","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-9","INVNAM":"Dr. USA-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":1.28053,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-18 19:43:32","TRTEDTM":"2023-07-19 13:43:32","TRT01SDTM":"2020-07-18 19:43:32","TRT01EDTM":"2022-07-19 07:43:32","TRT02SDTM":"2022-07-19 07:43:32","TRT02EDTM":"2023-07-19 13:43:32","AP01SDTM":"2020-07-18 19:43:32","AP01EDTM":"2022-07-19 07:43:32","AP02SDTM":"2022-07-19 07:43:32","AP02EDTM":"2023-07-19 13:43:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-19","EOSDY":1096,"LSTALVDT":"2023-08-09","ASEQ":4,"LBSEQ":4,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":3770,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":13.56069,"AVALU":"U/L","BASE2":13.92471,"BASE":13.56069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.36403,"PCHG2":-2.61426,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-06 19:43:32","ADY":141,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-9-id-130","SUBJID":"id-130","SITEID":"USA-9","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-9","INVNAM":"Dr. USA-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":1.28053,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-18 19:43:32","TRTEDTM":"2023-07-19 13:43:32","TRT01SDTM":"2020-07-18 19:43:32","TRT01EDTM":"2022-07-19 07:43:32","TRT02SDTM":"2022-07-19 07:43:32","TRT02EDTM":"2023-07-19 13:43:32","AP01SDTM":"2020-07-18 19:43:32","AP01EDTM":"2022-07-19 07:43:32","AP02SDTM":"2022-07-19 07:43:32","AP02EDTM":"2023-07-19 13:43:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-19","EOSDY":1096,"LSTALVDT":"2023-08-09","ASEQ":7,"LBSEQ":7,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":4173,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":7.87644,"AVALU":"U/L","BASE2":13.92471,"BASE":13.56069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-6.04828,"PCHG2":-43.43556,"CHG":-5.68425,"PCHG":-41.91712,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-02 19:43:32","ADY":199,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-9-id-130","SUBJID":"id-130","SITEID":"USA-9","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-9","INVNAM":"Dr. USA-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":1.28053,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-18 19:43:32","TRTEDTM":"2023-07-19 13:43:32","TRT01SDTM":"2020-07-18 19:43:32","TRT01EDTM":"2022-07-19 07:43:32","TRT02SDTM":"2022-07-19 07:43:32","TRT02EDTM":"2023-07-19 13:43:32","AP01SDTM":"2020-07-18 19:43:32","AP01EDTM":"2022-07-19 07:43:32","AP02SDTM":"2022-07-19 07:43:32","AP02EDTM":"2023-07-19 13:43:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-19","EOSDY":1096,"LSTALVDT":"2023-08-09","ASEQ":10,"LBSEQ":10,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5178,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":6.66033,"AVALU":"U/L","BASE2":13.92471,"BASE":13.56069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-7.26438,"PCHG2":-52.16899,"CHG":-6.90035,"PCHG":-50.88499,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-03-20 19:43:32","ADY":245,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-9-id-130","SUBJID":"id-130","SITEID":"USA-9","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-9","INVNAM":"Dr. USA-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":1.28053,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-18 19:43:32","TRTEDTM":"2023-07-19 13:43:32","TRT01SDTM":"2020-07-18 19:43:32","TRT01EDTM":"2022-07-19 07:43:32","TRT02SDTM":"2022-07-19 07:43:32","TRT02EDTM":"2023-07-19 13:43:32","AP01SDTM":"2020-07-18 19:43:32","AP01EDTM":"2022-07-19 07:43:32","AP02SDTM":"2022-07-19 07:43:32","AP02EDTM":"2023-07-19 13:43:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-19","EOSDY":1096,"LSTALVDT":"2023-08-09","ASEQ":13,"LBSEQ":13,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":1492,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":21.94229,"AVALU":"U/L","BASE2":13.92471,"BASE":13.56069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":8.01758,"PCHG2":57.57804,"CHG":8.38161,"PCHG":61.80813,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-27 19:43:32","ADY":252,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-9-id-130","SUBJID":"id-130","SITEID":"USA-9","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-9","INVNAM":"Dr. USA-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":1.28053,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-18 19:43:32","TRTEDTM":"2023-07-19 13:43:32","TRT01SDTM":"2020-07-18 19:43:32","TRT01EDTM":"2022-07-19 07:43:32","TRT02SDTM":"2022-07-19 07:43:32","TRT02EDTM":"2023-07-19 13:43:32","AP01SDTM":"2020-07-18 19:43:32","AP01EDTM":"2022-07-19 07:43:32","AP02SDTM":"2022-07-19 07:43:32","AP02EDTM":"2023-07-19 13:43:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-19","EOSDY":1096,"LSTALVDT":"2023-08-09","ASEQ":16,"LBSEQ":16,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":5001,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":14.39541,"AVALU":"U/L","BASE2":13.92471,"BASE":13.56069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.4707,"PCHG2":3.38031,"CHG":0.83473,"PCHG":6.15549,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-19 19:43:32","ADY":458,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-9-id-130","SUBJID":"id-130","SITEID":"USA-9","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-9","INVNAM":"Dr. USA-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":1.28053,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-18 19:43:32","TRTEDTM":"2023-07-19 13:43:32","TRT01SDTM":"2020-07-18 19:43:32","TRT01EDTM":"2022-07-19 07:43:32","TRT02SDTM":"2022-07-19 07:43:32","TRT02EDTM":"2023-07-19 13:43:32","AP01SDTM":"2020-07-18 19:43:32","AP01EDTM":"2022-07-19 07:43:32","AP02SDTM":"2022-07-19 07:43:32","AP02EDTM":"2023-07-19 13:43:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-19","EOSDY":1096,"LSTALVDT":"2023-08-09","ASEQ":19,"LBSEQ":19,"LBTESTCD":"ALT","LBTEST":"Alanine Aminotransferase Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<7","ASPID":788,"PARAM":"Alanine Aminotransferase Measurement","PARAMCD":"ALT","AVAL":1.22245,"AVALU":"U/L","BASE2":13.92471,"BASE":13.56069,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-12.70227,"PCHG2":-91.22102,"CHG":-12.33824,"PCHG":-90.98536,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-3","BTOXGR":"0","ADTM":"2021-12-14 19:43:32","ADY":514,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":7,"ANRHI":55,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"3","ATOXGRH":"","ATOXDSCH":"Alanine aminotransferase increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-9-id-130","SUBJID":"id-130","SITEID":"USA-9","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-9","INVNAM":"Dr. USA-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":1.28053,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-18 19:43:32","TRTEDTM":"2023-07-19 13:43:32","TRT01SDTM":"2020-07-18 19:43:32","TRT01EDTM":"2022-07-19 07:43:32","TRT02SDTM":"2022-07-19 07:43:32","TRT02EDTM":"2023-07-19 13:43:32","AP01SDTM":"2020-07-18 19:43:32","AP01EDTM":"2022-07-19 07:43:32","AP02SDTM":"2022-07-19 07:43:32","AP02EDTM":"2023-07-19 13:43:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-19","EOSDY":1096,"LSTALVDT":"2023-08-09","ASEQ":2,"LBSEQ":2,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3258,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.59418,"AVALU":"mg/L","BASE2":8.59418,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-09 19:43:32","ADY":22,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-9-id-130","SUBJID":"id-130","SITEID":"USA-9","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-9","INVNAM":"Dr. USA-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":1.28053,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-18 19:43:32","TRTEDTM":"2023-07-19 13:43:32","TRT01SDTM":"2020-07-18 19:43:32","TRT01EDTM":"2022-07-19 07:43:32","TRT02SDTM":"2022-07-19 07:43:32","TRT02EDTM":"2023-07-19 13:43:32","AP01SDTM":"2020-07-18 19:43:32","AP01EDTM":"2022-07-19 07:43:32","AP02SDTM":"2022-07-19 07:43:32","AP02EDTM":"2023-07-19 13:43:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-19","EOSDY":1096,"LSTALVDT":"2023-08-09","ASEQ":5,"LBSEQ":5,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1220,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.51071,"AVALU":"mg/L","BASE2":8.59418,"BASE":9.51071,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":0.91653,"PCHG2":10.66454,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-06 19:43:32","ADY":141,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-9-id-130","SUBJID":"id-130","SITEID":"USA-9","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-9","INVNAM":"Dr. USA-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":1.28053,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-18 19:43:32","TRTEDTM":"2023-07-19 13:43:32","TRT01SDTM":"2020-07-18 19:43:32","TRT01EDTM":"2022-07-19 07:43:32","TRT02SDTM":"2022-07-19 07:43:32","TRT02EDTM":"2023-07-19 13:43:32","AP01SDTM":"2020-07-18 19:43:32","AP01EDTM":"2022-07-19 07:43:32","AP02SDTM":"2022-07-19 07:43:32","AP02EDTM":"2023-07-19 13:43:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-19","EOSDY":1096,"LSTALVDT":"2023-08-09","ASEQ":8,"LBSEQ":8,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1226,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":8.88297,"AVALU":"mg/L","BASE2":8.59418,"BASE":9.51071,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.28879,"PCHG2":3.36027,"CHG":-0.62774,"PCHG":-6.60038,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-02 19:43:32","ADY":199,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-9-id-130","SUBJID":"id-130","SITEID":"USA-9","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-9","INVNAM":"Dr. USA-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":1.28053,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-18 19:43:32","TRTEDTM":"2023-07-19 13:43:32","TRT01SDTM":"2020-07-18 19:43:32","TRT01EDTM":"2022-07-19 07:43:32","TRT02SDTM":"2022-07-19 07:43:32","TRT02EDTM":"2023-07-19 13:43:32","AP01SDTM":"2020-07-18 19:43:32","AP01EDTM":"2022-07-19 07:43:32","AP02SDTM":"2022-07-19 07:43:32","AP02EDTM":"2023-07-19 13:43:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-19","EOSDY":1096,"LSTALVDT":"2023-08-09","ASEQ":11,"LBSEQ":11,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":3925,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.87898,"AVALU":"mg/L","BASE2":8.59418,"BASE":9.51071,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.71519,"PCHG2":-8.32185,"CHG":-1.63172,"PCHG":-17.15671,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-03-20 19:43:32","ADY":245,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-9-id-130","SUBJID":"id-130","SITEID":"USA-9","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-9","INVNAM":"Dr. USA-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":1.28053,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-18 19:43:32","TRTEDTM":"2023-07-19 13:43:32","TRT01SDTM":"2020-07-18 19:43:32","TRT01EDTM":"2022-07-19 07:43:32","TRT02SDTM":"2022-07-19 07:43:32","TRT02EDTM":"2023-07-19 13:43:32","AP01SDTM":"2020-07-18 19:43:32","AP01EDTM":"2022-07-19 07:43:32","AP02SDTM":"2022-07-19 07:43:32","AP02EDTM":"2023-07-19 13:43:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-19","EOSDY":1096,"LSTALVDT":"2023-08-09","ASEQ":14,"LBSEQ":14,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":2829,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":7.45019,"AVALU":"mg/L","BASE2":8.59418,"BASE":9.51071,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-1.14399,"PCHG2":-13.31121,"CHG":-2.06052,"PCHG":-21.66526,"ANRIND":"LOW","BNRIND":"NORMAL","SHIFT1":"NORMAL to LOW","ATOXGR":"-1","BTOXGR":"0","ADTM":"2021-03-27 19:43:32","ADY":252,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"Y","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"1","ATOXGRH":"","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-9-id-130","SUBJID":"id-130","SITEID":"USA-9","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-9","INVNAM":"Dr. USA-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":1.28053,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-18 19:43:32","TRTEDTM":"2023-07-19 13:43:32","TRT01SDTM":"2020-07-18 19:43:32","TRT01EDTM":"2022-07-19 07:43:32","TRT02SDTM":"2022-07-19 07:43:32","TRT02EDTM":"2023-07-19 13:43:32","AP01SDTM":"2020-07-18 19:43:32","AP01EDTM":"2022-07-19 07:43:32","AP02SDTM":"2022-07-19 07:43:32","AP02EDTM":"2023-07-19 13:43:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-19","EOSDY":1096,"LSTALVDT":"2023-08-09","ASEQ":17,"LBSEQ":17,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":5694,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.37167,"AVALU":"mg/L","BASE2":8.59418,"BASE":9.51071,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.77749,"PCHG2":9.04669,"CHG":-0.13904,"PCHG":-1.46195,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-19 19:43:32","ADY":458,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-9-id-130","SUBJID":"id-130","SITEID":"USA-9","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-9","INVNAM":"Dr. USA-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":1.28053,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-18 19:43:32","TRTEDTM":"2023-07-19 13:43:32","TRT01SDTM":"2020-07-18 19:43:32","TRT01EDTM":"2022-07-19 07:43:32","TRT02SDTM":"2022-07-19 07:43:32","TRT02EDTM":"2023-07-19 13:43:32","AP01SDTM":"2020-07-18 19:43:32","AP01EDTM":"2022-07-19 07:43:32","AP02SDTM":"2022-07-19 07:43:32","AP02EDTM":"2023-07-19 13:43:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-19","EOSDY":1096,"LSTALVDT":"2023-08-09","ASEQ":20,"LBSEQ":20,"LBTESTCD":"CRP","LBTEST":"C-Reactive Protein Measurement","LBCAT":"CHEMISTRY","LBSTRESC":"<8","ASPID":1645,"PARAM":"C-Reactive Protein Measurement","PARAMCD":"CRP","AVAL":9.36741,"AVALU":"mg/L","BASE2":8.59418,"BASE":9.51071,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.77323,"PCHG2":8.99712,"CHG":-0.1433,"PCHG":-1.50674,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-14 19:43:32","ADY":514,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":8,"ANRHI":10,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"C reactive protein increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-9-id-130","SUBJID":"id-130","SITEID":"USA-9","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-9","INVNAM":"Dr. USA-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":1.28053,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-18 19:43:32","TRTEDTM":"2023-07-19 13:43:32","TRT01SDTM":"2020-07-18 19:43:32","TRT01EDTM":"2022-07-19 07:43:32","TRT02SDTM":"2022-07-19 07:43:32","TRT02EDTM":"2023-07-19 13:43:32","AP01SDTM":"2020-07-18 19:43:32","AP01EDTM":"2022-07-19 07:43:32","AP02SDTM":"2022-07-19 07:43:32","AP02EDTM":"2023-07-19 13:43:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-19","EOSDY":1096,"LSTALVDT":"2023-08-09","ASEQ":3,"LBSEQ":3,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":2028,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.88602,"AVALU":"g/L","BASE2":2.88602,"BASETYPE":"LAST","ABLFL2":"Y","ABLFL":"","CHG2":0,"PCHG2":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-08-09 19:43:32","ADY":22,"ATPTN":1,"AVISIT":"SCREENING","AVISITN":-1,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-9-id-130","SUBJID":"id-130","SITEID":"USA-9","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-9","INVNAM":"Dr. USA-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":1.28053,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-18 19:43:32","TRTEDTM":"2023-07-19 13:43:32","TRT01SDTM":"2020-07-18 19:43:32","TRT01EDTM":"2022-07-19 07:43:32","TRT02SDTM":"2022-07-19 07:43:32","TRT02EDTM":"2023-07-19 13:43:32","AP01SDTM":"2020-07-18 19:43:32","AP01EDTM":"2022-07-19 07:43:32","AP02SDTM":"2022-07-19 07:43:32","AP02EDTM":"2023-07-19 13:43:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-19","EOSDY":1096,"LSTALVDT":"2023-08-09","ASEQ":6,"LBSEQ":6,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6238,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.81303,"AVALU":"g/L","BASE2":2.88602,"BASE":2.81303,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"Y","CHG2":-0.07299,"PCHG2":-2.52892,"CHG":0,"PCHG":0,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"","ATOXGR":"0","BTOXGR":"0","ADTM":"2020-12-06 19:43:32","ADY":141,"ATPTN":1,"AVISIT":"BASELINE","AVISITN":0,"LOQFL":"N","ONTRTFL":"","WORS01FL":"","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"","WGRLOVFL":"","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-9-id-130","SUBJID":"id-130","SITEID":"USA-9","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-9","INVNAM":"Dr. USA-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":1.28053,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-18 19:43:32","TRTEDTM":"2023-07-19 13:43:32","TRT01SDTM":"2020-07-18 19:43:32","TRT01EDTM":"2022-07-19 07:43:32","TRT02SDTM":"2022-07-19 07:43:32","TRT02EDTM":"2023-07-19 13:43:32","AP01SDTM":"2020-07-18 19:43:32","AP01EDTM":"2022-07-19 07:43:32","AP02SDTM":"2022-07-19 07:43:32","AP02EDTM":"2023-07-19 13:43:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-19","EOSDY":1096,"LSTALVDT":"2023-08-09","ASEQ":9,"LBSEQ":9,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":3849,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86628,"AVALU":"g/L","BASE2":2.88602,"BASE":2.81303,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01973,"PCHG2":-0.68373,"CHG":0.05325,"PCHG":1.89307,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-02-02 19:43:32","ADY":199,"ATPTN":1,"AVISIT":"WEEK 1 DAY 8","AVISITN":1,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"Y","WGRLOFL":"Y","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-9-id-130","SUBJID":"id-130","SITEID":"USA-9","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-9","INVNAM":"Dr. USA-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":1.28053,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-18 19:43:32","TRTEDTM":"2023-07-19 13:43:32","TRT01SDTM":"2020-07-18 19:43:32","TRT01EDTM":"2022-07-19 07:43:32","TRT02SDTM":"2022-07-19 07:43:32","TRT02EDTM":"2023-07-19 13:43:32","AP01SDTM":"2020-07-18 19:43:32","AP01EDTM":"2022-07-19 07:43:32","AP02SDTM":"2022-07-19 07:43:32","AP02EDTM":"2023-07-19 13:43:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-19","EOSDY":1096,"LSTALVDT":"2023-08-09","ASEQ":12,"LBSEQ":12,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":6400,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.87354,"AVALU":"g/L","BASE2":2.88602,"BASE":2.81303,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01247,"PCHG2":-0.43222,"CHG":0.06051,"PCHG":2.1511,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-20 19:43:32","ADY":245,"ATPTN":1,"AVISIT":"WEEK 2 DAY 15","AVISITN":2,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-9-id-130","SUBJID":"id-130","SITEID":"USA-9","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-9","INVNAM":"Dr. USA-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":1.28053,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-18 19:43:32","TRTEDTM":"2023-07-19 13:43:32","TRT01SDTM":"2020-07-18 19:43:32","TRT01EDTM":"2022-07-19 07:43:32","TRT02SDTM":"2022-07-19 07:43:32","TRT02EDTM":"2023-07-19 13:43:32","AP01SDTM":"2020-07-18 19:43:32","AP01EDTM":"2022-07-19 07:43:32","AP02SDTM":"2022-07-19 07:43:32","AP02EDTM":"2023-07-19 13:43:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-19","EOSDY":1096,"LSTALVDT":"2023-08-09","ASEQ":15,"LBSEQ":15,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":5142,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.86603,"AVALU":"g/L","BASE2":2.88602,"BASE":2.81303,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.01999,"PCHG2":-0.69249,"CHG":0.053,"PCHG":1.88407,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-03-27 19:43:32","ADY":252,"ATPTN":1,"AVISIT":"WEEK 3 DAY 22","AVISITN":3,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-9-id-130","SUBJID":"id-130","SITEID":"USA-9","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-9","INVNAM":"Dr. USA-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":1.28053,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-18 19:43:32","TRTEDTM":"2023-07-19 13:43:32","TRT01SDTM":"2020-07-18 19:43:32","TRT01EDTM":"2022-07-19 07:43:32","TRT02SDTM":"2022-07-19 07:43:32","TRT02EDTM":"2023-07-19 13:43:32","AP01SDTM":"2020-07-18 19:43:32","AP01EDTM":"2022-07-19 07:43:32","AP02SDTM":"2022-07-19 07:43:32","AP02EDTM":"2023-07-19 13:43:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-19","EOSDY":1096,"LSTALVDT":"2023-08-09","ASEQ":18,"LBSEQ":18,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":7014,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.9177,"AVALU":"g/L","BASE2":2.88602,"BASE":2.81303,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":0.03168,"PCHG2":1.09786,"CHG":0.10467,"PCHG":3.72087,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-10-19 19:43:32","ADY":458,"ATPTN":1,"AVISIT":"WEEK 4 DAY 29","AVISITN":4,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"} {"STUDYID":"AB12345","USUBJID":"AB12345-USA-9-id-130","SUBJID":"id-130","SITEID":"USA-9","AGE":40,"AGEU":"YEARS","SEX":"M","RACE":"ASIAN","ETHNIC":"NOT HISPANIC OR LATINO","COUNTRY":"USA","DTHFL":"N","INVID":"INV ID USA-9","INVNAM":"Dr. USA-9 Doe","ARM":"A: Drug X","ARMCD":"ARM A","ACTARM":"A: Drug X","ACTARMCD":"ARM A","TRT01P":"A: Drug X","TRT01A":"A: Drug X","TRT02P":"C: Combination","TRT02A":"C: Combination","REGION1":"North America","STRATA1":"A","STRATA2":"S1","BMRKR1":1.28053,"BMRKR2":"MEDIUM","ITTFL":"Y","SAFFL":"Y","BMEASIFL":"N","BEP01FL":"N","AEWITHFL":"N","RANDDT":"2020-07-17","TRTSDTM":"2020-07-18 19:43:32","TRTEDTM":"2023-07-19 13:43:32","TRT01SDTM":"2020-07-18 19:43:32","TRT01EDTM":"2022-07-19 07:43:32","TRT02SDTM":"2022-07-19 07:43:32","TRT02EDTM":"2023-07-19 13:43:32","AP01SDTM":"2020-07-18 19:43:32","AP01EDTM":"2022-07-19 07:43:32","AP02SDTM":"2022-07-19 07:43:32","AP02EDTM":"2023-07-19 13:43:32","EOSSTT":"COMPLETED","EOTSTT":"COMPLETED","EOSDT":"2023-07-19","EOSDY":1096,"LSTALVDT":"2023-08-09","ASEQ":21,"LBSEQ":21,"LBTESTCD":"IGA","LBTEST":"Immunoglobulin A Measurement","LBCAT":"IMMUNOLOGY","LBSTRESC":">3","ASPID":4743,"PARAM":"Immunoglobulin A Measurement","PARAMCD":"IGA","AVAL":2.83658,"AVALU":"g/L","BASE2":2.88602,"BASE":2.81303,"BASETYPE":"LAST","ABLFL2":"","ABLFL":"","CHG2":-0.04944,"PCHG2":-1.71305,"CHG":0.02355,"PCHG":0.83704,"ANRIND":"NORMAL","BNRIND":"NORMAL","SHIFT1":"NORMAL to NORMAL","ATOXGR":"0","BTOXGR":"0","ADTM":"2021-12-14 19:43:32","ADY":514,"ATPTN":1,"AVISIT":"WEEK 5 DAY 36","AVISITN":5,"LOQFL":"N","ONTRTFL":"Y","WORS01FL":"Y","WGRHIFL":"","WGRLOFL":"","WGRHIVFL":"Y","WGRLOVFL":"Y","ANL01FL":"Y","ANRLO":0.8,"ANRHI":3,"BTOXGRL":"0","BTOXGRH":"0","ATOXGRL":"0","ATOXGRH":"0","ATOXDSCH":"Immunoglobulin A increased"}